Studies in Natural Products Chemistry Volume 31 Indices (Part A)
Studies in Natural Products Chemistry edited by Atta-ur-Rahman
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Stereoselective Synthesis (Part A) Structure Elucidation (PartA) Stereoselective Synthesis (Part B) Stereoselective Synthesis (Part C) Structure Elucidation (Part B) Stereoselective Synthesis (Part D) Structure and Chemistry (PartA) Stereoselective Synthesis (Part E) Structure and Chemistry (Part B) Stereoselective Synthesis (Part F) Stereoselective Synthesis (Part G) Stereoselective Synthesis (Part H) Bioactive Natural Products (Part A) Stereoselective Synthesis (Part I) Structure and Chemistry (Part C) Stereoselective Synthesis (Part J) Structure and Chemistry (Part D) Stereoselective Synthesis (Part K) Structure and Chemistry (Part E) Structure and Chemistry (Part F) Bioactive Natural Products (Part B) Bioactive Natural Products (Part C) Bioactive Natural Products (Part D) Bioactive Natural Products (Part E) Bioactive Natural Products (Part F) Bioactive Natural Products (Part G) Bioactive Natural Products (Part H) Bioactive Natural Products (Part I) Bioactive Natural Products (Part J) Bioactive Natural Products (Part K) Indices (Part A)
Studies in Natural Products Chemistry Volume 31 Indices (Part A)
Edited by
Atta-ur-Rahman
H.E.J. Research Institute of Chemistry, University of Karachi, Karachi 75270, Pakistan
2005
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FOREWORD The present index volume comprises the contents of previous 30 volumes published in this series. I hope that it will allow the readers to readily extract the required information from any of these volumes. The volume comprises 4 separate indices, which are: ~
.
,
.
Cumulative General Subject Index Cumulative Organic Synthesis Index Cumulative Pharmacological Activity Index Cumulative Biological Source Index
This separation into different indices should also facilitate the readers in respect of obtaining the information required. I would like to express my thanks to Mr. Liaquat Raza and Ms Qurat-ul-Ain Fatima for their assistance in the preparation of the index. I am also grateful to Mr. Waseem Ahmad for the typing work and to Mr. Mahmood Alam for secretarial assistance.
Atta-ur-Rahman
Ph.D. (Cantab.), Sc.D. (Cantab.) Director, H.E.J. Research Institute of Chemistry, Chairman (Federal Minister), Higher Education Commission
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oo
VII
CONTENTS
Foreword
V
Cumulative General Subject Index Cumulative Organic Synthesis Index
871
Cumulative Pharmacological Activity Index
1007
Cumulative Biological Source Index
1225
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Indices
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CUMULATIVE GENERAL SUBJECT INDEX VOLUMES 1-30
AI adenosine agonists 25:265 somatostain as 25:265 opiates as 25:265 A1 and AzA-adenosine 25:895 A2-agonists 25:265 A-549 (human lung adenocarcinoma) 30:588 activity of (-)-deoxypodophyllotoxin against 30:588 activity of (-)-yatein against 30:588 1AA oxidation 25:657 inhibitor of 25:657 AADC 30:380 activity of 30:380 deficiency of 30:380 in abnormal sleeping 30:380 in eye movement abnormalities 30:380 in feeding difficulties with esophagea reflux 30:380 C-Aalkylation 10:412 AAPM [(2,2'-azobis (2-amidino propane) dihydrochloride)] 26:763 Aargesin 26:241 Aaronsohnia sp. 29:683 AB-1006 A9 21:411 ABA 27:341,354 of l'-methyl ether 27:341 photoisomerization of 27:354 [3',5,7-2H6] ABA 27:353 Abamectin (avermectin B) 12:9 ABC-transporter family 21:158 Abdominal constriction test 30:207 activity of (-)-menthol in 30:207 Abdominal pain 30:203,205 use of ginseng root in 30:203 use of Psycotria colorata in 30:205 1 l(15~l)Abeataxan 20:80,100,101 (3~20)Abeataxan 20:80,106 25-(10~9)Abeo-26(8~ 15) abeo913,1413,15Gt-olean-5-ene-313,29-diol 5:744,748,750
19(4-->3)-Abeo-8 ct, 13(S)-epoxylabda4(18), 14-diene 29:102 activity in EBV bioassay system 29:102 9( 10--~19)Abeo-diene steroidal alkaloids 2:205,206 Abernaemontana penduliflora 28:234 Aberrant crypt foci (ACF) 25:65 Abies amabnilis 22:391 Abies balsamea 22:384 from balsam 22:384 Abies grandis 22:391 Abies koreana 20:619 Abies mariestii 20:619 Abies marocana 29:99 Abiesen 20:283 Abiesenonic acid 25:60 methyl ester 25:60 19-nor-Abieta-4(18),8,11,13-tetraen-7one 29:100 activity in EBV assay system 29:100 Ent-Abieta-8(14), 13(15)-dien- 16,12olide (jolkiolide E) 9:283,284,290 Abieta-8,11,13-trien-7-one 29:99 activity in EBV assay system 29:99 18-nor-Abieta-8,11,13-triene-4c~,7c~, 15triol 29:99 activity in EBV assay system 29:99 Abieta-8,11,13-triene-7cz, 15,18-triol 29:99 activity in EBV assay system 29:99 Abieta-8,11,13-triene-7c~,l 5,18-triol 7acetate 29:99 activity in EBV assay system 29:99 Abietane 9:297 Abietane diterpenoids 20:660-680; 23:682 Abietatriene 2:402,403
Abietatriene-6-one 14:669,670,673, 674,676 Abietic acid 29:99,188 activity in TPA assay system 29:99 activity in CRG assay system 29:99 pisiferic acid synthesis from 29:188 Abiotic stress 23:741 Abisapogenol 25:95 Abnormal Beckmann rearrangement 16:133 4-AboA 27:193,203,204,225 formation of 27:204 Abramov reaction 6:353 Abri Herba 25:99 antihepatotoxic effect of Ogs from 25:99 Abrisapogenol A 25:96 Abrisapogenol B 25:96 Abrisapogenol C 25:96 Abrisapogenol D 25:96 Abrisapogenol F 25:97 Abrisapogenol I 25:97 Abrisapogenol L 25:96 Abrisaponin 25:97 Abrisaponin A 25:96 Abrisaponin C 25:96 Abrisaponin D2 25:96 Abrisaponin D3 25:96 Abrisaponin D~ 25:96 Abrisaponin I 25:97 Abrisaponin L 25:96 Abrisaponin SB 25:95 Abrisaponin SO~ 25:95 Abrus contaniensis 25:93 Abrus fruticulosus 15:26;27:15 abrusoside A from 27:15 abrusoside B from 27:15 abrusoside C from 27:15 abrusoside D from 27:15 Abrus precatorius 7:152,15:25; 21:674 ;22:510;25:93 ;27:15,27 abrusoside A from 27:15,27 abrusoside B from 27:15,27 abrusoside C from 27:15,27 abrusoside D from 27:15,27 abrusoside E from 27:15,27
cycloartane from 21:674 for epilepsy 22:510 Abrus sp. 25:180 Abrusgenic acid 7:152 Abrusoside A 27:15,27,28 structure of 27:28 Abrusoside B 27:15,27,28 structure of 27:28 Abrusoside C 27:15,27,28 structure of 27:28 Abrusoside D 27:15,27,28 structure of 27:28 Abrusoside E 27:15,27,28 structure of 27:28 Abscisic acid 25:367;27:330,331,322, 335,337,352,388 activity of 27:331 biological activity of 27:332 conformations of 27:335 IH-NMR spectra of 27:339 metabolic inactivation of 27:322 NOE experiment of 27:338 structure of 27:321 utility of 27:331 (-)-Abscisic acid 27:346 formation of 27:346 (+)-Abscisic acid 27:346 formation of 27:346 Abscisic acid analogs 27:321,323-329 activity of 27:483 Abscisic acid ring 27:336,338 interconversion of 27:336 Abscisic acid-GE 27:354 hydrolysis of 27:354 Abscisic aldehyde 27:321 in biosynthesis 27:321 Absidia sp. 25:160 Absinthin (guaine sesquiterpene dimer) 29:574 effects on HIV- 1 protease 29:574 Absintholide (guaine sesquiterpene dimer) 29:574 effects on HIV-1 protease 29:574 Absolute configuration 9:27 by CD procedure 9:27 by Horeau procedure 9:25,26 by Nakanishi's method 2:89
in 24-(13-hydorxyethyl)-in 24(carboxy-methyl) steroids 15:79-81 in 24-ethyl-26-hydroxysteroids 15:84 in 24-hydroxymethyl steroids 15:79 in 24-hydroxysteroids 15:76,77 in 24-methyl-25,26-dihydroxysteroids 15:84-86 in 24-methyl-26-hydroxy and 24-methyl-26-oic steroidal sidechains 15:81-84 in 26-hydroxysteroids 15:77,78 of (+)-aristoserratine 11:296 of (+)-monomoriwei 6:449,450 of (-)-hobartine 11:290 of (-)-peduncularine 11:284 of 3c~,13-dihydroxy- 11epiapotrichothecenes 13:520 of amphotericin B 6:231 ofaureol 9:31 ofbenzo [a] pyrene oxide 7:8,14 ofcarotenoids 7:321 of decaprenoxanthin 7:355 of liverwort sesquiterpenoids 18:607-646 of Mosher's esters 13:77 of penems 4:435 ofphoracantholide I,J 6:546 of quinocarcin 10:126 of R, S-4-hydroxycyclopentenones 6:315 of sclerosporin 6:549-551 of sigmosceptrellins A-C 9:16 of solenopsin B 6:430 of sugars saponins 15:190 of taxol 11:3,7 of thienamycin 4:433,436 of urdamycin A 11:134 Absolute stereostructure 28:11 ofbroussonetine C 28:11 ofbroussonetine L 28:12 AB TS (2,2'-azino-bis-( 3-ethylthiazoline6-sulfonic acid) 26:1014,1015,1020 oxidation of 26:1016 Abyssinian tea 23:653 (2S)-Abyssinone II 28:17 as aromatase inhibitor 28:17
Acacetin (5,7-dihydroxy-4'-methoxyflavone) 29:571 inhibition of HIV- 1 protease 29:571 Acacia astringens 7:427 Acacia auriculiformis 21:674;23:487, 498;26:467 triterpenoid saponin from 21:674 Acacia catechu 29:678,680 Acacia confusa 29:603 Acacia honey 28:386 aroma of 28:386 Acacia melanoxylon 27:838 Acacia nilotica 7:427;26:358 Acacia spp. 29:582 Acacia tomentosa 7:427 Acaciamine 23:498 Acaciaside A 21:674;23:497 Acaciaside AB 26:467 Acaciaside B 21:674;23:497 Acaciaside C 23:497 Acalycigorigia inermis 5:370 Acalycigorigia sp. 5:368,369 Acalyphafruticosa sk. 22:510 for epilepsy 22:510 Acalyphafruticosa Forsk. 22:510 for epilepsy 22:510 Acanthacerebroside A 18:481 Acanthaster planci 7:288 acanthaglycosides A-D,F from 7:288 marthasteroside A from 7:288 thomasteroside A from 7:288 Acanthella acuta 21:329;25:848, 852,853 Acanthella aurantica 21:270 Acanthella cavernosa 21:351,353,355, 356,359,361,365-367 ;25:689,858; 26:465;28:663 10-epi-isokalihinol H from 28:663 15-isothiocyanato- 1-epikalihinene from 28:663 Acanthella klethra 20:525;25:848, 852;26:810;28:662 isothiocyanates from 28:662 Acanthella pukherrina 25:853;28:660 isothiocyanates from 28:660 sesquiterpenes from 28:660
Acanthella pulcherrima 25:852 Acanthella sp. 21:334;25:852,853; 28:663 kalihinol G of 28:663 kalihinol H of 28:663 Acanthenes A-C 21:334 Acanthicifoline 7:191 Acanthifolicin 5:384;28:710;25:832 episulfide group of 28:710 Acanthodendrilla sp. 25:704;28:702 acanthosterol sulfate A of 28:702 acanthosterol sulfate B of 28:702 acanthosterol sulfate C of 28:702 acanthosterol sulfate D of 28:702 acanthosterol sulfate F of 28:702 acanthosterol sulfate G of 28:702 acanthosterol sulfate H of 28:702 acanthosterol sulfate I of 28:702 acanthosterol sulfate J of 28:702 antifungal activity of 28:702 A canthodris nanaimoensis 19:139 Acanthoic acid 29:103 activity in TNFc~ bioassay system 29:103 Acantholippia seriphioides 21:618 Acanthomyops claviger 6:454 Acanthopanax koreanum 29:103 Acanthophyllum gypsophiloides 26:3 Acanthophyllum squarrosum 24:149; 26:31,50,55 squarroside A from 26:31 Acanthophyllum squarrosum 26:55 immunomodulatory effect of 26:55 Acanthoscelides obtectus 10:160 Acanthosterol sulfate A-J 25:704 Acanthus ebracteatus 7:176 Acanthus illicifolius 7:176,179,181,182, 189-191,193 Acanthus mollis 27:188,191 Acarapis woodi 28:387,390 in honey bees' tracheal tubes 28:387 infestations in Minnesota 28:390 Acarbose 13:3 as or-amylase inhibitor 13:3 as ot-glucosidase inhibitors 7:47 as antihyperglycemic drug
10:505 as antihyperlipoproteinaemic drug 10:505 Acaria saxatilis 22:634 Acaricidal activities 24:799;28:403,406, 412,422 against Dermatophagoides pteronyssinus 28:422 against Psoroptes cuniculi 28:412 against Rhipicephalus appendiculatus 28:406 for killing adult ticks 28:403 of caffeine 28:422 ofCuminum cyminum 28:427 of essential oils 28:412,427 of Eucalyptus camaldulensis 28:427 of eugenol 28:403 of extract prepared by microwave assisted process (MAP) 28:427 of Lavandula angustifolia 28:412 oflinalool 28:412 of Margaritaria discoidea 28:406 of Origanum syriacum var. bevanii 28:427 of phenylpropanoid derivatives 28:403 of Pimenta dioica 28:403 ofPimpinella anisum 28:427 of Tanacetum vulgare extracts 28:427 of 13-thujone 28:427 Acaricidal properties 28:400,406 of benzaldehyde 28:406 of carvacrol 28:406 of cedrene 28:406 of c~-cyclocitral 28:406 of [3-cyclocitral 28:406 of Euphorbia obovalifolia latex 28:400 of Ficus brachypoda latex 28:400 of geraniol 28:406 of (E)-geranylacetone 28:406 of c~-ionone 28:406
of linalool 28:406 of m-cymene 28:406 of methyl salicylate 28:406 of nerol 28:406 of nerolidol 28:406 of nonanal 28:406 of 13-ocimene 28:406 ofphenylacetaldehyde 28:406 of phenylacetonitrile 28:406 of c~-terpineol 28:406 Acaricide 28:381,429,435 cross-resistance of 28:429 Acarnus bergquistae 25:724 Acarus siro 28:382,423 as mite sp. 28:382 Acarviosin 22:177 Acarviosine 10:503,504,506 Accedine 5:125 Accedinine 5:125 Accedinisine 5:125 Acer nikoense 26:889,895,899 Acer saccharumn 25:666 Acer sp. 21:502;26:905 Acernicoense 17:358,367-368,375 Acerogenin A 17:367,375;20:276 Acerogenin A-L 26:899 Acerogenine-E 17:368 Acerolide 23:175 Aceroside I 17:367 Aceroside IV 17:367 Aceroside V 17:367 Aceroside VII 17:358 Aceroside XI 17:368;26:895 Acerosterol 23:177 Acesulfame-K 15:4 Acetal 6:336 Acetaldehyde dependent aldolase (DERA) 30:428 Acetalization 1:584 trans-Acetalization 4:325,326,331, 338,339,495 6-Acetamido-2,3,4-tri-O-allyl-6-deoxya-glucoheptopyranosiduronic acid 11:434,435 2-Acetamido-2-deoxy-D-glucopyranose 6:351 2-Acetamido-2-deoxy-D-glucopyranosides 6:389
2-Acetamido-2-deoxyglucomannans 5:286,287 5-Acetamido-3,5-dideoxy-D-glycero-Dgalacto-2-nonulosonic acid 30:420 2-Acetamidofluorene 26:1003 p-Acetamidophenyl- 1,4,4'-dithiocellotrioside 8:351 p-Acetamidophenyl- 1,4-dithiocellobioside 8:350,351 14-Acetamidosantonin 24:124,125 Acetaminophen 26:257;30:192 as analgesic/antipyretic 30:192 Acetaminophenone 25:219,614 Acetate/mevalonate pathway 25:130 Acetobacter suboxydans 17:636-637 Acetobromoglucose 10:366,367 [3-Acetochloromannose 8:321,322 Acetogenic cyclic peroxides 9:18 Acetogenins 9:385,391,392,395,397399,403;18:193-227;19:81 Acetolysis 30:489 (-)-Acetomycin 10:443 antimicrobial activity of 10:443 antitumor activity of 10:444,447 (+)-5-epi-Acetomycin 10:447 antitumor activity of 10:447 Acetonide 14:160;19:489 Acetonitrile 22:205 Acetonylbutanolides 17:273 Acetophenone 2:169,170;25:666 Acetophenone phenylhydroazone 9:581 3-Acetoxy monomethyl phthalates 14:5 19-Acetoxy- 11-methoxytabersonine 2:375 3 [3-Acetoxy-11-ursen- 13~,30-olide 654,656 IR spectrum of 30:654 NMR spectroscopic data of 30:654 structure of 30:656 16-Acetoxy- 12-O-acetyl-horminone 15:169,170,173 2c~-Acetoxy- 14-hydroxy- 15-iso-valeroyloxy-9-oxo-costunolide 29:89 activity in NFkB assay system 29:89 activity in TNFc~ assay system 29:89
( 15R)- 15-Acetoxy- 15,20-dihydrocatharanthine 14:815 20-Acetoxy- 15,20-dihydrocatharanthine 4:32 (15'S)- 15'-(Acetoxy-20'-deoxyvinblastine 14:815,816 from (15R)-I 5-acetoxy-15,20dihydro catharanthine 14:815,816 1ot-Acetoxy-20Ctv-hydroxy-24tx,25c~epoxywitha-5-ene-22,26-olide-413-0glucopyranoside 20:191 22-Acetoxy-23,24-dinorchola- 1,4,6trien-3-one 11:398 (+)- 1-Acetoxy-2-epipinoresinol 5:538-540 1ct-Acetoxy-2ct,6[3,9[3-trifuroyloxy-4[3hydroxy-dihydro-[3-agarofuran 29:87 4-Acetoxy-3 [ 1'-tert-butyldimethylsilyloxy) ethyl]-2-azetidinone 4:448 20S-Acetoxy-3 [3-16-dihydroxylanost-7en-18-oic acid-18,16-1actone 7:~269 3-Acetoxy-4-hydroxybenzaldehyde 8:166,167 9ot-Acetoxy-4 [3,15-epoxymiller- 1( 10)-Zenolide 29:89 activity in NFkB assay system 29:89 2R, 3R-(+)-3-Acetoxy-5,7,4'-trihydroxyflavanone 27:34,35 structure of 27:35 Ac etoxy-5,7- dihydroxy-4 '- metho xy flavanone 27:34,35 structure of 27:35 (+)- 1-Acetoxy- 6- epipinoresinol 5:538-540
8ot-Acetoxy-6-epi-tannunolide A 27:583 1-Acetoxy-6cx-hydroxy-germacran1(10), 3(4)-dien-8,12-olide 27:561 16-Acetoxy-7,8-epoxy-3,12dolabelladien-13-one 20:491 2-Acetoxy-8,13-dihydroxy- 11-epi APO 13:522 12-Acetoxy-8,13-dihydroxy- 11-epiapotrichothec-9-ene 9:20
7fl-Acetoxy-8,13-epoxy- 1a,6/3,9 atrihydroxylabd- 14-en-11-one 25:256 1[3-Acetoxy- 8 [3-hydroxyeudesm-4(15), 7-diene-8-12-olide 20:660 3 [3-Ac etoxy- 8 [3-i sobutyrylo xy-re ynos in 29:87 activity in Mam-2 assay system 29:87 activity in DIF assay system 29:87 15-Acetoxy-9ct-hydroxy-8 [3-methacryloyloxy- 14-oxo-acanthospermolide 29:89 activity in NFkB assay system 29:89 15-Acetoxy-9cz-methacryloyloxy-8 f3hydroxy- 14-oxo-acantho-spermolide 29:89 activity in NFkB assay system 29:89 5-Acetoxyarctigenin monoacetate 18:601 6'-Acetoxyavarol 15:301 1-Acetoxybutadiene 1:571 l'-Acetoxychavicol acetate 23:800 25-Acetoxycholesta- 1,4,6-trien-3-one 11:385 2tx-Acetoxycholestanone 18:888 2[3-Acetoxycholestanone 18:888 3-Acetoxycostunolide 29:89 activity in NFkB assay system 29:89 (+)-Acetoxycrenulide 18:22-28 15-Acetoxy-eremantholideB 29:89 activity in NFkB assay system 29:89 activity in TNFet assay system 29:89 l'-Acetoxyeugenol 23:800 12-Acetoxyfamesol acetate 27:586 3-Acetoxyflavanones 30:729 structure of 30:729 tx-Acetoxyfuranone 12:14 3-Acetoxyguaiazulene 14:321 23S-Acetoxyholost-7-en-3 [3-ol 7:273 613-Acetoxyho lo sta-7,24-dien- 3 [3-ol 7:275
23S-Ace to x yho losta- 7,25 -dien- 313-o1 7:273 16otAcetoxy-holosta-7-en-3b-ol 7:2771-Acetoxyisocomene 3:6,60 6-Acetoxyldihydrochelerythrine 27:168 313-Acetoxymalabarican- 14(26), 17E,21 triene 27:591 ent- 13-epi- 12a-Acetoxymanoyl oxide 25:273 10-Acetoxymenthol 25:160 6-Acetoxymethyl-2,6-dimethyl-9methoxy tricyclo [5.3.01'5] undec-9en-8,11-dione 8:163 5-Acetoxymethyltrachelogenin 18:602 5-Acetoxymethyltrachelogenin monoacetate 18:602 9a-Acetoxy-miller- 1(10)-Z-enolide 29:89 activity in NFkB assay system 29:89 13-Acetoxymodhephene 3:6,61 18-Acetoxy-Na-deacetylisoretuline 1:38-39 18-Acetoxynorfluorocurarine 1:38-39 (+)- 1-AcetoxypinoresinoI-[3-D-glu 26:200 (+)- 1-Acetoxypinoresinol 5:523,533, 538,544;26:200 (+)-Acetoxypinoresinol dimethyl ether 26:241 as PAF-induced inhibitor 26:241 (+)- 1-Acetoxypinoresinol-4"-O-methyl ether 5:523,533-535 (+)- 1-Acetoxypinoresinol-4"-O-methyl ether-4'-[3-D-glucoside 5:523 (+)- 1-Acetoxypinoresinol-4'- 13-Dglucoside 5:523 6[~-Acetoxy-pseudotropanol 21:751 3-Acetoxypyrrol-2(5H] -one 13:117, 118 (+)- 16c~-Acetoxytabersonine 2:186 8cc-Acetoxy-tannunolide E 27:585 5-Acetoxytrachelogenin diacetate 18:601 6[3-Acetoxy-tropanone 21:751 6ot-Acetoxyvouacapan- 17,7 [3-1actone 29:103
activity in AOS bioassay system 29:103 13-Acetoxy-cx-diazoesters 30:447 reaction of 30:447 15-Acetylcardiopetamine 26:869 N-Acetyl cysteamine 13:496 Acetyl pyrazine 13:320 ~-Acetyl alcohol 14:462 Acetyl CoA carboxylase 25:525 3-Acetyl deoxynivalenol 13:520,521, 536 N-Acetyl glucosamine 7:31,47,49 ~3-(1-3)-N-Acetyl glucosaminyltransferase 10:484 N-Acetyl isomuramic acid 6:386,387 O-Acetyl isophotosantonic lactone 14:357 Acetyl kaikasaponin 25:95 N-Acetyl muramic acid 7:31,47,49 N-Acetyl neuraminic acid (NANA) 13:207-210 O-Acetyl normacusine B 13:386 O-Acetyl preperakine 13:387 O-Acetyl villamine 13:396 2-O-Acetyl-(S)-(+)mandelic acid 13:468,469 Na-Acetyl- 11,12-dihydroxyaspidospermatiine 1:40 Na-Acetyl- 11-hydroxyaspidospermatidine 1:40 Acetyl-11-keto-13-boswellic acid (triterpene) 29:585 effects on LELA 29:585 6-O-Acetyl-2,3,4-tri-O-benzyl-Dglucono- 1,5-1actone 12:335 3-Acetyl-2,6-dimethylpyridin-4-one 13:545 7'-Acetyl-2-methoxypicropodophyllin 30:586 2-Acetyl-3,5-dihydroxy- 1-geranoxy-6methyl-4-(2-methyl)butyryl-benzene 30:615 structure of 30:615 3-Acetyl-4,6-dimethylpyridin-2-one 13:545 1-O-Acetyl-4-methoxylycorine 26:100, 615
10
acetylation of secologanin 26:100,615 (7R, 8S,7 'R,8' R)-(+)-7 '-Ac etyl- 5 'methoxypicropodophyllin 30:586 ~3CNMR comparison of 30:586 circular dichroism (CD) spectrum of 30:586 ~H NMR comparison of 30:586 HREIMS of 30:586 molecular formula of 30:586 ROESY correlation of 30:586 ROESY NMR of 30:586 stereochemistry of 30:586 4-Acetyl-6,8-dihydroxy-5-methyl-3,4dihydroisocoumarin 15:409 17-O-Acetylajmaline 9:183-185 Acetylamino- 1,2-dihydroacronycine 20:800 2-Acetylamino-3H-phenoxazin-3-one 27:219 structure of 27:219 5-Acetylamino-6- formyl amino-3methyluracil 22:5 Acetylaminonaphthoquinone 9:437 Acetylandromedol 20:27 Acetylannulatophenonoside 30:624 N,,-Acetylaspidospermatidine 1:40 Acetylastrogaloside I 25:193 3-Acetylated flavanones 798 Acetylation 19:480 ofsyn alcohol 19:480 [3-Acetylation procedure 10:447 for acetomycin synthesis 10:447 stereoselective 10:447 Acetylation reaction 23:172 oftobagolide 23:172 2-Acetylbutyrolactone 8:284,285 Acetylcholine 22:15,29;25:516,519, 520,527,530,547 nicotinic receptor for 25:519 vasodilator effect of 25:595 Acetylcholine esterase 22:16 Acetylcholine receptor 18:863 Acetylcholine-gated Na+/K+channels 25:527 Acetylcholinesterase 7:18 Acetylcholinesterase inhibitors 21:585 Acetyl-coenzyme A 7:112
(+)-N-Acetylcolchinol 29:376 allocolchicinoids total synthesis of 29:376 19-Acetylcorrin 9:600,601 3-Acetylcoumarins 368 2-O-Acetyl-D-glucal tetraacetate 10:414 (+)-Acetyldomesticine 16:519 Acetylenation 1:611,612 of acetals diastereoselective 1:611,612 Acetylene-C-glycosides 10:359 Acetylenes 23:341 ct,[~-Acetylenic alcohols 4:493 Acetylenic compounds 30:706 C-Acetylenic hexopyranose 10:374 Acetylenic oxy-Cope rearrangement 8:250 3-O-Acetylerythrodiol 25:59 2'-Acetylglaucarubinone 7:379,380 N-Acetylglucosamine 1:417 Acetylglucosamine 30:95 molecular weight of 30:95 [3-N-Acetyl-glucosaminidases 12:346 [3-(1-6)-N-Acetylglucosaminyltransferase 10:486 in biosynthesis of I-antigens 10:486 3-Acetylgoniotriol 9:394 (+)- 8-Acetylgonoiotril 19:463 8-Acetylharpagide 29:83 activity in EBV, liver-l, lung-2, skin-1, skin-4 assay systems 29:83 Acetyl-histamines 15:328 Acetyl-horminone 20:670 N-Acetylisocodonocarpine 9:73-75,77 O-Acetyl-isopseudolycorine 26:614 O-Acetylisoretuline 1:38,39 N-Acetyllactosamine (2-acetamido-2deoxy-4-O-[3-D-galactopyranosyl-c~D-glucose) 10:459,461-467 3-Acetylleptophylline-A 20:486,487 1-O-Acetyllycorine 26:615 Acetylmelodorenol 9:400,152 N-Acetyl-muramyl-(L)-alanyl-(D)isoglutamine(MPD) 13:210-212
11 N-Acetyl-muramyl-L-alanyl-D-isoglutaminyl -S-tert-butyl-c ysteamine 18:927 Nb-Acetyl-Nb-methyltryptamine 9:178 7-Acetylneotrichilenone 9:297 Acetylneuraminate pyruvate lyase 11:466,467 N-Acetylneuraminic acid 10:550; 30:420,425 synthesis of 30:425 5-N-Acetylneuraminic acid 27:104 3-19-Acetyloleanane 25:59 Acetyloleanolic acid 25:59 Na-Acetyl-O-methyl strechnosplendine 9:188 (+)-Acetylphomalactone 19:479 antifungal activity of 19:479 antitumor activity of 19:479 insect antifeedant activity of 19:479 plant growth inhibitory effect of 19:479 (7R,8S,7'R,8 'R)-(+)-7'-Acetylpicropodophyllin 30:568,593 use of soft agar transformation assay 30:593 Acetylpipitzol 5:778 O-Acetylpolyneuridine 5:128 4~-O-Acetyl-pseudoguain-6~-olide 29:90 activity in TPA assay system 29:90 3-Acetyl-pyrrolidine-2,4-diones 14:100 O-Acetylretuline 1:38,39 Acetylsalicylic acid 26:162;30:192 from willow-derived salicylic acid 30:192 synthetic derivatives of 26:162 O-Acetylsolasodine 20:489;22:28 N-Acetylsolasodine 20:490 Acetylsoyasaponin 25:95 Acetylstrychnovoline 6:523,524 3-Acetylteumicropin 23:617 13C-NMR data of 23:617 IH-NMR data of 23:617 (+)-Acetylthaliporphine 16:519 2-Acetylthiazole (2-ATT) 11:443,444 Acetyltrimethylammonium bromide 27:509
O-Acetylvallesamine 9:167,168,171 Acetylvismione D 7:418-420,424 3-Acetyl- [3-D-digitoxose 15:362 N-Acetyl-[3-D-hexosainidase 7:416,417 3-Acetyl-[3-1actam 12:152,161 Ach receptor 21:92,98 Achantaster planci 15:45 AChE activity 21:748 AChE inhibitor 21:749 Acheta domesticus 22:387;29:6 Achillea arten 21:378 tetradecadienoylpyrrolidine from 21:378 Achillea millefolium 10:151;21:378; 24:686,688-690 Achillea nana 10:151;21:378 Achillea nobelikii 24:687-689 Achillea pannonica 29:88 Achillea ptormica 24:691 Achillea setacea 29:89 Achillea sp. 24:684,687;29:683 Achillea sudetica 24:687 Achillin 7:234 Achiral heptanal 12:55 Achyranthes aspera L. 22:510 for hysteria 22:510 Achyranthes fauriei 29:10 Achyrocline flaccida 22:347 7,4-dihydroxy-5-methoxy flavone from 22:347 Achyrocline satureioides 22:346 as antispasmodic 22:346 as choleretic 22:346 as hepatoprotective 22:346 quercetin from 22:346 Acicerone 27:498 Aciclovir (9-[2-hydroxyethoxy methyl] guanine) 10:585 antiviral activity of 10:585 Aciculites orientalis 26:1214 Aciculites sp. 26:1175 Aciculitins A-C 26:1214 Acid-catalysed aldol condensation 30:217 of phenylacetone 30:217 Acid-catalysed cyclization 30:217 of 1-benzyl- 1,2,3,4-tetrahydro isoquinolines 30:217
12 Acid-catalysed methanolysis 30:44 Acid-catalysed rearrangement 6:115; 23:487,515 of aglycones 23:487,515 of (+)-endo-3-bromocamphore 16:147 of spiro cyclic lactone 16:225 Acid-induced abdominal contraction test 30:205 activity of (+)-allomatrine in 30:205 activity of (+)-matrine in 30:205 Acid-labile protecting groups 30:441 Acifluorfen 25:669 Acilius sulcatus 5:700 Acinetobacter calcoaceticus 12:103; 27:218 Acinos suaveolens 30:276 apigenin from 30:276 Acinosolic acids A,B 7:144,145 Aclacinomycine A 4:317,318 Acnistus arborescens 20:247 Acnistus breviflorus 20:234 Acomycota 22:246 basidiomycetes from 22:246 Aconin 20:22 Aconite 24:898-899 neuromuscular blocking effect of 24:898-899 trans-Aconitic acid 26:793,794 Aconitine 20:22;21:98,109;22:17; 24:898-900;26:868,869,870,871 as anti-inflammatory agent 24:898 as cardiotonic agent 24:898 for relieving muscle pain 24:898 Aconitum 26:868 Aconitumjaponicum. 22:510 for convulsions 22:510 Aconitum napellus 20:19 [3-Acoradiene 15:261,262 ot-Acoradiene 15:262 Acoradienes 5:734 c~-Acorene 15:260 (-)-Acorenone 16:222 Acorenone B 21:231 Acorospora gobiensis 25:802
Acorus calamus L. 21:595;22:510; 28:401 in hysteria, convulsions and epilepsy 22:510 Acorus caninum 26:471 Acorus graminous 26:362,470 Acosmium panamense 27:269 (cis-ACPC) 22:273,275 Acquired immunodeficiency syndrome (AIDS) 23:3;25:734,941,948;30:412 Acrasiomycetes 9:220 Acremonium sp. 27:805 Acridine 25:542 based PKA inhibitor 25:542 Acridone alkaloids 13:347-382 Acrolein 21:308 Acromelic acid 21:70 Acronychia baueri 13:347,349;20:789 Acronychia oigophylebeia 13:348,350 oligophylidine from 13:348,350 Acronycine 13:365-375 antitumor activity of 13:365-375 Acronycine azine 20:791 Acronym SNAP 21:16 Acroscyphus sphaerophoides 5:310 Acrostalagmus genus 21:221 ;28:454 Acrostalamus fungi 28:455 acrostalidic acid from 28:455 acrostalic acid from 28:455 isoacrostalidic acid from 28:455 Acrylamide reagents 4:45,18:320 Acrylonitrile 14:551 Acrylonitrile reagents 18:318 Ac-SAMM 2 23:29,37 ~3C-NMR assignments of 23:31 IH-NMR assignments of 23:29 structure elucidation of 23:37 ACT1-VII 22:265 Actaea 25:180 Actamycin 9:248,250 Acteoside 5:507;25:468,543 (ACTH) 25:265 [3-Actin 30:779 cytokine mRNA expression of 30:779 Actinase E 25:438 Actinidia deliciosa 26:1145,1158 Actinidia polygama Miq. 16:290,291 Actinobacter calcoaceticus 30:421
13 (+)-Actinobolin 16:3 antineoplastic activity of 16:3 as microbial antitumor antibiotics 16:3 dental cariostatic activity of 16:3 immunosuppressive activity of 16:3 Actinocin 26:1009 Actinodaphne lancifolia 28:419 Actinoerythrol 30:526 structure of 30:526 Actinogyra muelenbergii 5:311-313 Actinomadura 26:451 Actinomadura hibisca 23:343 Actinomadura melliaura 12:366,368 AT 2433-A1 and A2 from 12:366, 368 AT 2433-Bland B2from 12:366, 368 Actinomadura sp. SF-2370 5:55;12:366 K-252a (SF-2370) from 368 Actinomadura spiralis 25:776 Actinomyces naeslundii 21:607 Actinomyces viscosus 21:613;23:536 Actinomycetales 19:559 Actinomycete strain (LIA-0788) 21:414 altamycin A from 21:414 Actinomycetes 21:186,263,265;22:80; 29:230 Actinomycin 26:1009 Actinomycin D 21:608;24:547;25:58, 461,479;26:1009 antiviral microbial-derived compound 24:547 Actinomycin synthetase I, II and III 26:1010 Actinoplanes coloradoensis 17:283 Actinoplanes sp. 25:777;28:147 effect on K-cells-IL2-activated killer cells 25:273 K-cells-IL2-activated killer cells 25:273 Actinoplanic acids 24:428-429 activity against VSV, HSV-1, poliovirus SV, FMDV 24:524 structure of 24:428,429 Actinopyga agassizi 7:267,269;21:315 holothurins from 7:267,269
Actinopyga echinites 7:269 echinoside A&B from 7:269 Actinopyga mauritiana 7:281 Actinorhodin 22:265 Actinostemma lobatum 21:634 Action potential 21:8 Activators 27:833 from Daphne cannabina 27:833 from Daphne mezereum 27:833 from Thymelaceous plants 27:833 from Wikstroemia indica 27:833 5-Active peptide analogues 30:801 synthesis of 30:801 Activities 22:354;25:257;27:323,331, 333,504,513 for Astragalus spp. 27:483 from Phyllanthus amarus 27:840 of Astragali radix 27:513 of abscisic acid 27:331,352 of abscisic acid analogs 27:323-329 of diarylheptanoids 27:852 of enzymes 27:378 of flavonoids 27:504 of fluorinated probes 27:333 ofhydrolysable tannins 27:840 of labdane 25:257 of monoterpenes 27:384 ofodour substances 27:378 ofphosphorylase kinase 27:852 of protein kinases 27:826 of serine 27:850 of threonine 27:850 of tyrosine 27:850 of xanthine oxidase 22:354 activity in AOS bioassay system 29:103 activity in DIF assay system 29:90 activity of 17:378;25:257 activity against A549 (human lung adenocarcinoma) 30:588 activity against HT-29 (human colon carcinoma) 30:588 activity against KB-16 (human oral epidermal carcinoma) 30:588 activity against P-388 (murine
14 lymphocytic leukemia) 30:588 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:589 platelet aggregation inhibitor 30:594 macrolide as 17:16 sesquiterpene dialdehydes 17:233 epothiolones as 24:406 Actomysin ATPase-activating activity 23:193 of penaresidin A 23:193 ofpenaresidin B 23:193 Aculeanic acid 23:343 Acuminatin 26:199 Acuminatopyrone 13:544,545 Acumycin 5:613 Acute diarrhoeal disease 30:747 Acute gastritis 30:153 Helicobacter pylori as causative agent of 30:153 Acute hepatitis 30:406 chemotherapy of 30:406 Acute leukemia 14:805 in children 14:805 vinblastine for 14:805 vincristine for 14:805 Acute myocardial infarction (AMI) 30:839,844 use of fibrinolytic agent 30:839 Acute pain 30:799 analgesic alkaloid in 30:799 Acute phase proteins 25:461 Acute rheumatism 26:398,400 Acute toxicity 27:307 of stevioside 27:307 of steviol 27:307 Acyclic 11-carboxy- 12-nor-transnerolidol 29:87 activity in EBV assay system 29:87 Acyclic cis-nerolidol 29:87 activity in EBV assay system 29:87
Acyclic trans-nerolidol 29:87 activity in EBV assay system 29:87 Acyclovir 21:694,698;24:474,486; 25:116;26:226 as anti-viral agent 24:474,486 Acyl carrier protein (ACP) 22:265; 25:501,509 Acyl group 23:403 in oligomers 23:403 3-Acyl tetramic acid 28:111,112,114 tautomeric forms of 28:112 Adenichrome 28:647 Fe(III)-containing pigment as 28:647 11c~-Acyl turkesterone 29:19 as synthetic ecdysteroid analogues 29:19 6ot-Acylamino radical 12:44 Acylase group 6:551 Acylated amidines 5:574 Acylated carotenoid glucosides 30:523 salimixanthin 30:523 thermozeaxanthin 30:523 Acylated flavonol-glycosides 17:142 Acylated guanidines 5:574 Acylated polyhydroxy-oleanene-3-Omonodesmosides 21:675 N-Acylated tetramic acid 21:415 N-Acylation 16:22 with Cbz-L-alanine 16:22 Acylation 30:627 of hexaenal 6:264,267 selective 6:283,284 with N,N-diisopropylcarbamoyl chloride 10:15 intramolecular 16:18 with Cbz-L-alanine 16:18 with ethylchloroformate 16:19 N-Acylaziridines 13:150 Acylfulvenes 26:713 Acylglycerol 12:392 O-Acylglycosyl bromides 14:172 Acyliminium ion cyclization 1:244; 12:305,320,335 N-Acyliminium ion cyclization 11:290 intramolecular 11:284,285 N-Acyliminium ion-polyene cyclization 12:464
15
N-Acyliminium ion-vinylsilane cyclization 12:453 3-C-nitromethylene derivative 10:412 C-nucleosides 10:337,338,355, 358,388-394 of arylethanals 30:215 ofbioflavours 25:125 ofchlorogenic acid 25:919,930, 935 of furanone 12:13 of glucopyranoside 6:388 of N-substituted amides 10:215 of phosphocombretastatin (disodium salt) A-4 24:406 of potassium kojate 12:261 of silyl enol ether/acetone 11:296,297 of syringaresinol 24:741 of yangambin 24:741 of w-haloalcohol 8:195 of (x-D-glucopyranoside 6:385 parts of 30:707 p-hydroxyacetophenones from 30:731 propiophenone derivative 30:731 pipecolic acid 12:280 D-pyranosides 10:340 Csynthesis of 10:340 reaction with aldehydes 1:584 reaction with ketones 1:584 ribofuranoside 10:376 [3-Cribofuranosyl cyanide 10:356 13-D-ribose 10:337 role of nitric oxide in 26:921-923 sesquiterpenes from 30:706 stannic chloride catalysed 4:328, 329 C-sucrose 11:469,470 synthesis of 11:469,470 synthesis of 24:755-762 testing of 26:376 D-threo-hex-2-enone- 1,4-1actone 20:859 2-Acylindoles 1:51 1-Acylindoles photoisomerisation 1:51 [1,3]-Acylmigration 1:51
N-Acylmuramoyl-peptides 6:393 Acylneuraminic acids 27:104 Acylnitroso Diels-Alder reaction 1:386, 4:606 Acylnitrosocycloaddition 19:355 N-Acylnorreticuline 18:74 Acylovir-resistant HSV-1 25:940 N-Acylpyrrol-2(5H)-ones 13:110,111 3-Acylpyrrol-2(5H)-ones 13:112,113, 141 3-Acylpyrrolidinone 13:121,122,133, 139 3-Acylpyrrolin -2,5-diones 13:114, 125,129 3-O-Acylquinic acids 25:921 5-O-Acylquinic acids 25:921 N-Acylsphingosines 18:714 Acyltetramic acid 21:410 3-Acyltetramic acids 14:97 Acyltransferase (AT) 22:265 Adamantane 9:116 Adaptation 27:529 of plants to selenium 27:529 Addiction 30:799 by analgesic alkaloid 799 1,4-Addition 24:6 of hydride 24:6 syn Addition 8:296-298,304 Addition reaction 12:35-62 of chiral vinyllithium compounds 12:35-62 to c~-methyl-substituted aldehyde 12:35-62 1,4-Addition reaction 14:696,697 Addition-elimination mechanism 11:185,187 for 5-enolpyruvylshikimate 3phosphate synthase 11:185,187 anti-Adduct 30:447 from 3-bromopropyne 30:447 of carrageenans 30:410 of cationic polysaccharide (PS) 30:402 of dextran sulphate 30:410 of fucoidan 30:410 of mannans 30:402 of pentosan polysulphate 30:410 of polyphenols 30:224 of polysaccharides 30:393,395
16 of quinones 30:324-326 of sulphated galactan 30:402 of sulphated polysaccharide (PS) 30:403 of xylogalactans 30:402 of yeast mannans 30:412 on infected vero cells 30:410 Adenanthera pavonina 29:603 Adenine-thymine 22:27 Adenocarcinoma 1:276;26:712 of colon 1:276 Adenocorticorophic hormone(ACTH) 25:265 Adenohypophysical hormones 25:265 Adenosine 22:21;27:394;30:384 conversion of 30:384 from glucose 27:394 from red ginseng roots 27:394 structure of 27:396 Adenosine A1 receptors 25:532 Adenosine A2A 25:532 Adenosine receptors 22:25,20 Adenosine-5'-triphosphate (ATP) 25:948 ;27:820;30:369,384 Adenosine-5 '-diphosphate (ADP) 27:405 5-Adenosyl-L-methionine (SAM) 25:506 Adenosylmethinonine 25:828 S-Adenosyl-L-homocysteine (SAH) 25:509 S-Adenosyl-L-methionine (SAM) 25:509 S-Adenosylmethionin-decarboxylase inhibitor 26:830 S-Adenosyl-methionine 1:408 S-Adenosylmethionine (SAM) methylation 9:42,599,21:316 S-Adenosylmetionine: caffeate 3-0metyl transferase 5:468 Adenylate cyclase activator 25:488 Adenylate cyclase system 25:493 Adenylyl cyclase 25:532 inhibition of 25:532 Aderostenedione 25:419 Adhyperforin 22:645,653;30:612 structure of 30:612 ADI (acceptable daily intake) 27:308 for stevioside 27:308
Adiantum spp. 29:573,580 Adipokinetic hormones 9:487,489 Adipose tissue 30:81 Adipose tissue distribution 26:1130 as syndrome type-lA 26:1130 Adiposin-1 and 2 10:514 inhibitory activity against c~amylases 10:514 Adiposin-D 10:513 Adiposins 10:514 antibacterial activity of 10:514 et-glucosidase inhibitors of 10:513 Adjuvant activity 21:646,650;22:119; 26:55 of Gypsophila 26:55 of Quillaia 26:55 of Saponaria 26:55 Adjuvant induced polyarthritis 25:46 inhibition of 25:46 Adocia sp. 25:695,723,861 ;28:674 adociaquinone A from 28:678 adociasulfate from 28:674 from Great Barrier Reef 28:674 Adociaquinone A 25:862 Adociaquinone B 25:862 Adociaquinones 25:861 Adociasulfates 25:695 Adociidae family 28:664 10-isothiocyanatobiflora-4,15diene of 28:664 spectral analysis of 28:664 ADP-ribosylcyclase 25:535 Adrenaline 22:308;30:58 intravenous infusion of 30:58 a2-Adrenergic 25:530 type G-protein-linked receptor 25:530 Adrenergic activity 23:356 of coumarin 23:335,353,356, 357,368,376,393,550,553 Adrenergic agonists 21:109 Adrenergic alkaloids 21:68 Adrenergic antagonists 21:57;25:530 Adrenergic blocker 22:19 [3-Adrenergic blocking agents 14:473 synthesis of 14:473 c~-Adrenergic neurons 21:18
17 [~-Adrenergic neurons 21:18 ~x-Adrenergic receptor 21:18 [32-Adrenergic receptor 21:51 [3-Adrenergic receptor kinase 21:264 Adrenergic receptors 21:57;22:19; 25:271,530 c~i-Adrenergic receptors 21:90 c~2-Adrenergic receptors 21:90 [32-Adrenergic receptors 27:825 (x-Adrenoceptors 25:30 [3-Adrenoceptors 22:667 Adriamycin 14:474 4-demethoxy analogs of 14:474 synthesis of 14:474,475 Adriamycin-resistant P-333 cell 21:264 Aedes aegypti 9:299;26:439 Aegiceras comiculatium 7:176-178,180, 185,195 Aegiceras floridium 7:176-178 Aegilops ovata 26:187 A egle marmelos 21:599 Aegopodium podagraria 27:687 Aeolanthus suaveolens 22:509,511 in convulsions 22:511 Aeridoteres tristis 5:837 hemoglobin components of 5:837 Aerobacter aerogenes 11:183 Aerobacter ganera 29:311 Aeromenas salmonicida 4:197;23:238; 25:259 A eromonas hydrophila 4:197 Aeroplysinin 21:307;25:718 Aeroplysinin- 1 21:259,260 Aeropyruin pernix 25:720 Aerugidiol 29:90 activity in HPT assay system 29:90 (+)-Aerugin 19:821 Aeruginosin 25:205,799 Aeschynomene indica 25:93 [3-Aescin 21:657 Aesculetin 7:224 Aesculin 7:224;23:357 Aesculus chinensis 29:574,575 Aesculus glabrus 15:191 Aesculus hippocastanum 7:142,143; 21:657,666
escins from 21:666 escins Ia,Ib,IIa and IIb from 21:657 A esculus indica 7:142,143 aesculosides A,B from 7:142 triterpenes of 7:142,143 Aesculus saponins 15:191 Aethiopinone 29:100 activity in CRG assay system 29:100 Aethoxyamericanolide E 23:161 Aferoside A 824 Affinisine 5:123,126;9:179;13:386,429 ~t-Affinity 30:807 in guinea pig brain membranes 30:807 in rat brain synaptosomes 30:807 Affinity chromatography 30:825 8-Affinity 30:807 with deltorphins 30:807 Aflastatin A 28:127,128 as aflatoxin inhibitor 28:128 structure of 28:128 Aflastatin B 28:127,128 as aflatoxin inhibitor 28:128 Aflatoxin B-1 22:266;26:271,304 Aflatoxin B2 23:363 Aflatoxin inhibitor 28:128 aflastatin A as 28:127,128 aflastatin B as 28:127 Aflatoxin M2 14:651-657 Norrish type II reaction 14:651-657 Afraegle paniculata 22:511 as anticonvulsant 22:511 Aframomum aulacocarpos 25:259,266 Aframomum danielli 25:257,260 Aframomum hanburyi K. Schum. 27:17,34 3-acetoxy-5,7-dihydroxy-4 'methoxyflavnone from 27:17, 34 Aframomum pruinosum 27:34 African swine fever virus (ASFV) 30:410,412 effect of marine microalgae on 30:410 in vitro 30:410 transmission of 30:410
18
African trypanosomiasis (HAT, sleeping sickness) 26:784 African trypanosomiasis (HAT, sleeping sickness) 26:784 (+)-Africanol Claisen rearrangement 6:51 Afrocurarine 1:126 Afrormosin isoflavones 27:498,499 Afzelia bipendensis 9:256 bipendensis from 9:256 Agaricales 9:203 Agaricus blazei 28:569 isolation of 28:569 Agarofurans 23:811 ;30:695 Agastache foeniculum 29:571 Agastache rugosa 29:574 Agastanol (diterpene) 29:574 effects on HIV- 1 protease 29:574 Agastaquinone (diterpene) 29:574 effects on HIV- 1 protease 29:574 Agathis robusta 25:252 Agatophyllum aromaticum 21:616 Agavaceae 7:427;21:673 Agave cantala 7:427 Agel-489 13:650 Agelas clathordes 25:860 Agelas dendromorpha 25:792 Agelas dispar 25:706,710,722,777; 28:692 pyridine betaine B of 28:692 Agelas mauritiana 25:688,722,784, 870;28:689 Agelas mauritianus 18:460,467 agelasphins from 18:460,467 Agelas nakamurai 6:28;25:688,712, 780,860;28:670 antispasmodic activity of 28:670 agelasin-B from 6:28 agelasidine A from 28:670 agelasidine B from 28:670 antispasmodic activity of 28:670 Na+/K+-transporting adenosine triphosphate (ATP)ase inhibitor from 28:670 Agelas novacaledoniae 25:710 Agelas oroides 21:270;25:703;26:819; 28:690
Agelas sceptrum 21:270 sceptrin from 21:270
Agelas sp. 6:28;25:709,712,722,779 agelasins from 6:28
Agelas sponge 25:688 Agelas wiedenmayeri 25:712 Agelasidine A 28:670 synthesis of 28:670 Agelasidine B 25:861 ;28:670 synthesis of 28:670 Agelasidines A-D 25:860,861 (+)-Agelasidines B and C 25:860,861 Agelasimine A 25:688,792,793 Agelasimine B 25:688 Agelasimines 25:687 Agelasine 21:79 Agelasphins 25:722 Agelenopsis aperta 19:675 Ageliferin 25:779,780 Ageratina adenophora 5:28 Ageratoriparin 20:282 Ageratum fastigiatum 5:728 Ageratum houstonianum 22:395,396 Age-related mascular degeneration 30:525 role oflutein in 30:525 role ofzeaxanthin in 30:525 Agglutination 30:204 inhibition by hederagenin monodesmosides 30.204 Agglutination inhibitors 2:308,309 Aggregation 25:358,360 ofheme into hemozoin 25:360 of porphyrin and metalloporphyrin systems 25:358 Aggregation pheromone 1:692 of Gnathotrichus 1:692 Aggreticin 5:597 platelet aggregating inhibitor 5:597 Aging 30:224 role of free radicals in 30:224 Aglaia elliptica 26:218 aglaiastatin from 26:220 4'-demethoxy-3',4'-methylenedioxy-methyl rocaglate from 26:218 1-oxo-4'-demethoxy-3',4'-methylenedioxyrocaglaol from
19 26:218 4 '-demethoxy-3 ',4 '-methylenedioxyrocaglaol from 26:218 1-O-formyl-4'-methylenedioxymethylrocaglaol from 26:218 Aglaia odorata 22:511 ;26:220 in convulsions 22:511 pyrimidinone from 26:220 rocaglaol from 26:220 Aglaiastatin 26:220 Aglaonema treubii 24:917 Aglaophenia pluma 5:353 Aglycone 15:362;23:487,515;27:667, 929 anomeric configurations in 27:667 acid-catalysed rearrangement of 23:515 Aglycone-indolocarbazole 21:263 AGM-1470 (TNP-470) 22:262 Agmatine 22:724 Agmatine (1-amino-4-guanidino-butane) 530 Agmenellum quadruplicatum 26:358 Agnuside 29:84 activity in COX assay system 29:84 g-Agonist 30:799,801 dermorphins as 30:799 inhibitory effects of 30:801 8-Agonist 30:799,807 deltorphins as 30:799 [LeuS]enkephalin as 30:807 8-Agonist (D-Ala2) deltorphin II 30:801 evaluation of 30:802 Agonist effect 25:533 of oripainine 25:533 la-Agonist tetrapeptide 30:813 k-Agonist U-50 30:807 activity in GPI assay 30:807 Agonistic activity 21:68,95 Agonists 21:51 Otz-Agonists 8:396-298 Agratis ipsilon 7:397 Agricultural application 27:321 of abscisic acid 27:321 Agricultural pests 28:423 of forage crops 28:423
of fruits 28:423 of ornamentals 28:423 of timber 28:423 of vegetables 28:423 Agrimonia eupatoria 29:581 Agrimonia pilosa 23:396 Agrimonic acid A 23:3963Agrimonic acid B 23:397 Agroastragalaoside IV 25:197 Agroastragalaside I 25:197 Agroastragaloside II 25:197 Agrobacterium aurantiacum 21:299 Agrobacterium radiobacter 21:185 Agrobacterium rhizogenes 15:376,377; 17:395,421; 22:740;26:640,641 Agrobacterium sp. 7:76;25:395,659, 711,878 Agrobacterium tumefaciens 9:386,388; 21:185;22:740;23:267,268;25:395, 399 Agrochelin 25:711,878 Agrocin 21:84 21:185 Agrocinopine 21:185 Agroclavine 11:199,200;21:68 Agrocybe cylindracea 23:139 Agrofoglio 29:461 carbafuranose synthesis by 29:461 Agropyron repens L. 26:696;27:191, 216 allelopathic interaction of 27:21 Agrostemma githago var. githago 26:49 Agyl glycosides 7:53-58 AH-b-X model 27:10 AI-77-A to G 15:390 AI-77-B 15:393,396,397,402,404, 412-418 AI-77-G 15:392 AIBM 21:746 AIBN (2,2'-azobisisobutyronitrile) 6:353;19:340;481 AIDS 2:421-426;21:297,616,661,665; 22:248;30:226,396 mechanism of action of 30:226 AIDS virus 12:245 AIDS-associated lymphoma 21:138 Ailanthinone 7:379,380,398;26:815,816 Ailanthone 7:394,398 Ailanthus altissima 7:392,394;23:296
20
Ailanthus grandis 7:369,381 Ailantinol A 23:317 cytotoxicity of 23:317 Ailantinol-B 23:314,315 Ailantinol-C 23:314,315 Ailantinol-D 23:315 Ajmalicine 21:57,96 Ajmaline 9:183-185;13:403,404,424426;15:469 ;21:73,96,97,102,108 Ajmalinimine 9:183-186 Ajoene 28:432 acaricidal activity of 28:432 against Tetranyehus urticae 28:432 anticoagulant properties of 28:432 E-Ajoene 459,468 Z-Aj oene 468 Ajoenes 26:795,796,797 Ajuga decumbens 29:83,111 Ajuga reptans 29:24 Ajugalactones 20:248 Ajugol 7:455 Akaterpin 28:673 as phosphatidylinositol phospholipase C inhibitor 28:673 stereochemistry of 28:673 Akebia quinata 22:97 Akendo 29:100 activity in TPA bioassay system 29:100 activity in CRG bioassay system 29:100 Akicenin 5:722,723 Akiferidin 5:722,723 Akiferin 5:722,723 Aklavinone 4:317,327-329,333,341, 342;11:121-123 Akuammicine 1:35:1:45;5:123;9:190, 192;14:751 (Z)-Akuammidine 15:466,467 Akuammidine 5:24,123,127;9:171 (E)-Akuammidine (rhazine) 13:403 Akuammigine 9:171 ;25:31 Akuammiline 5:80,126,9:194,195 Akuammine 21:68,72
A1-Abed and Seepersaud 29:460 carbaketofuranose synthesis by 29:460 Alachlor 25:669 Alacocarpines A & B 25:266 ALA-dehydrase 9:604 Alamethicin 21:224 Alane 1:455 Alanine 21:738;22:21 ;25:264,400 Alanine derivatives 30:216 Alanine transaminase (ALT) 25:475 [3-Alaninookadaic acid 5:385,388 Alantolactone 26:463 Alaria sp. 26:1121 Alarm pheromone 6:453,454 n-undecane in 6:453,454 Alaternin 30:321 as antioxidant 30:321 Alatol 18:745 9-epi-Alatol 18:746 Albanin D 28:229 biological activity of 28:229 Albanin F 28:230 biological activity of 28:230 Albanin F and G 4:618 Albanol A 28:17,230 as aromatase inhibitor 28:17 biological activity of 28:230 Albanol B 28:229 biological activity of 28:229 Albartin 7:224 Albati 17:198 Albazoin 17:19 Albicanol 17:14 Albicanyl acetate 17:14;21:318 Albifloranine 9:171 Albiflorin 22:508,528,540 Albioside I 25:95 Albioside II 25:95 Albizzia harveyi 22:511 for epilepsy 22:511 Albizziajulibrissin 25:208;29:603 Albizzia lebbeck L. 22:511 Albizzia sp. 26:1157 Alboinon 23:257 Albomycin 9:555 Alcaligenes eutrophus 1:690;4:39;8:299 Alcaligenes faecalis 23:116;25:718
21
A lcaligenes faecalis var. myxogenes 5:314 (+)-Alchorneine 16:439 [3-Alcohol 19:248 Alcohol and D. Gal N models 25:463 Alcohol consumption 30:374 autistic features in 30:374 Alcohol dehydrogenase 17:479 Alcohol dependence 30:799 Alcohol inversion 1:456,457,459 Alcohol protection 1:558 as MEM ether 1:558 Alcohols 30:442 diastereomeric mixture of 30:442 Alconil 22:171 Alcyonacea 21:272,279 Alcyonidium gelatinosum sp. 18:695; 28:619,716 (2-hydroxyethyl) dimethylsulfoxonium ion from 28:619 Dogger Bank itch by 28:619 Aldehyde oxidase 22:5 Aldehydes 30:431 Aldimine 18:680 Alditols 9:499 Aldobiuronic acid 26:1157 1-Aldo-C-glycosides 10:350,351,389 Aldoheptofuranoses asymmetric quaternization 10:428-432 Johnson-Claisen rearrangement in 10:432-436 Aldohexoses 10:414,415 Aldol condensation 13:448,468;24:728, 729;30:213,215,423,433,472 acid-catalyzed 16:216,220 anti-Aldol condensation 30:435 Aldol condensation-intramolecular cyclization 30:217 Aldol coupling reactions 11:435-439 Aldol cyclization 6:49,50;24:201 2-amino alcohol by 12:411,414 asymmetric 4:327 chiral acetals in 4:329 chiral synthons for 4:491 of c~-sulfinylesters 4:491-494 of aldehyde 12:174,411,414 ofascorbic acid 4:699-705 in (+)-spatol synthesis 6:40,41
stereoselective 12:154 with enolsilyl ether 12:174 with isonitrile 12:411,414 with N-acylimine 12:160 Aldol reactions 13:206;30:438 from alditols 30:438-445 intramolecular McMurry approach 13:602 Aldol stereoselectivity 12:72 Aldol syntheses 30:434 from acyclic aldoses 30:434-438 Aldol type addition 16:656 Aldol type condensation 8:426,427 of aldehydes 8:426,427 with 2-trimethylsiloxy-3methylfuran 8:426,427 Aldolase-catalyzed stereocontrolled 30:423 Aldolases 30:423 in metabolism of 30:423 Aldolization 6:7,9,10,17 Aldol-type cyclization reaction 29:436 in alkaloids synthesis 29:436 Aldol-type reaction 12:36 stereocontrolled 12:36 stereoselective 12:166 Aldose aldehydes 30:446 elongation of 30:446 Aldose reductase 25:263,264;30:697 Aldose reductase inhibition 6:20;21:593 alkaloids in 21:3,20,109 as medicine 21:109 biorational plant protectants 21:109 by (+)-dysideapalaunic acid 6:20 by ion channels 21:3,20 Aldose reductase inhibitor 22:166; 28:691 from Dictyodendrilla sp. 28:691 (1--~ 1)-Aldosyl aldoside 1-thiodisaccharides 8:317-322 (1 ~2)-Aldosyl ketoside 1-thiodisaccharides 8:322-326 Alectoria sarmentosa 5:310,311 Alectoria sulcata 5:310,311 Alexa leiopetala 11:267;12:332,342; 27:255 (+)-castanospermine from 11:267;12:332
22 (+)-6-epi-castanosperime from
12:342 (1S,6S,7R,8R,8aR)-tetrahydroxyindolizidine from 12:332 Alexandrium fundyense 18:703 Alexandrium ostenfeldii 18:703 Alexandrium tamarebnsuis 7:703 Alexandrium tamarensis 17:4;18:703 Alexandroside I 25:214,198 Alexine 7:13,14,10:567,568 Alfalfa 23:343 Alfentanil 30:200 as morphine analogue 30:200 Algae 9:321 ;30:521 Algal and cyanobacterial toxicity 26:376 testing of 26:376 Algicidal activity 26:358 Alginasic 24:995-998 enzymatic activity of 24:995-998 Alginic acid 26:1150,1151,1152 Algoane 25:804 Alianthus malabarica 21:273 Alicyclic amino acid 22:293 Aliphatic pentaene phytofluene 30:518 Alizarin 25:543,544;26:635-640,642, 649,656-658,670-673,875 ;30:336 1-methylether of 26:658,673 2-methylether of 26:659 synthesis of 26:635-637,642 use for dyeing 30:336 S-Alk(en)ylcysteine sulfoxides 457 Alkaline hydrolysis 27:671 Alkaline phosphatase 21:160 Alkaline phosphatase activity 26:378, 382 Alkaloid 23:241;24:527-533;30:563, 596,799 as analgesic 30:799 as antiviral compound 24:527-533 in vivo antimalarial assay 30:596 in vivo intrinsic activity of 30:596 molluscicidal activity of 7:427 Alkaloid 223A 29:439 2,3,5,6-tetrasubstituted piperidine moiety of 29:440 as trialkyl-substituted
indolizidine class member 29:439 C-6 epimer synthesis in 29:442 conjugate addition reaction in 29:441 homologs of 29:439 of dart-poison frog alkaloid 2071 29:444 stereochemistry of 29:444 stereoelectronically favored axial attach in 29:443 stereoselectivity of 29:443 structure of 29:439 Alkaloid AG- 1 1:127 Alkaloid glycoside 24:123,132,133 Alkanoic acid 21:612 Alkanol 7:231 asymmetric hydration of alkene 13:451 asymmetric hydroboration of alkene 13:451,452 oxyamination of alkene 12:411, 413 photochemical additions to alkene 1:642 Alkenals 2:10 A3'4Alkene 12:22 Alkenols 2:10 o-Alkenyl dehydroglycosides 3:245 Alkenyl phenols 7:427 molluscicidal activity of 7:427 6-Alkenyl-4-oxapyran-2-ones 10:340 by enolate Claisen rearrangement 10:340 Claisen rearrangement of 3:245 hydroboration of cis-alkenes 8:471,472 thermolytic cyclization of 6:429 Alkenylcopper-phosphine complex 8:189 Alkenylhydroquinones 9:321,329 (Z)-N-Alkenylinitrone 19:29 N-Alkenylurethanes 19:29 Alkhanin 7:231 [3-Alkoxy diazo ketones 12:27,28 3-[(c~-Alkoxy)-Gt-methoxy]-2thioxopyrrolidines 26:1097
23 3-[(oc-Alkoxy)-~x-methylthio]-methyl-2thioxopyrrolidines 26:1097 1-Alkoxyalkyl-cz-glucosides 7:51 Alkoxyalkyl-[3-glucosides 7:51 (~,-Alkoxyallyl) stannanes 11:442,443 Alkyl 1-thioglycoside 8:347 Alkyl 1-thioxylosides 8:315 Alkyl 4-thiodisaccharide 8:332,333 sec-Alkyl boronic ester 11:409,411,412 Alkyl citrates 24:433 structure of 24:433,434 Alkyl esters 27:334 of Abscisic acid 27:334 Alkyl ketones 14:645 Alkyl maltotrioside 8:346,347 Alkyl phenols 21:591 Alkyl quinones 5:821 c~-Alkyl c~-amino acids 10:411 Alkyl [3-D-galactoside 8:316 2-Alkyl- 1,4-naphthoquinones 5:823,824 4-Alkyl-2-buten-4-olides 3:166,167 3-Alkyl-5-arylimidazolidinediones 30:198 as CB~ cannabinoid receptor 30:198 as pharmacophore 30:198 tra ns-2-Alkyl-5-h ydro x yp iperi dines 13:486 3-Alkyl-8-hydroxy-3,4-dihydroisocoumarins 15:386 Alkylated p-terphenyls 29:291 xylerythrin group of 29:291 Alkylation 10:408,409;14:491-499; 24:2,10,11,14,22,23,25,201,210,749; 30:627 N-Alkylation 16:99,104 reductive 16:99,104 with D-glyceraldehyde 16:99,104 with L-glyceraldehyde 16:99 O-Alkylation 6:385 ~,-Alkylation 6:76,77 in (+)-sinularene synthesis 6:76,77 S-Alkylation 8:214;13: 145 intramolecular 13:145 Alkylcysteine sulfoxides 23:458 1-N-Alkyl-deoxynoj irimycins 7:46
3-C-Alkyl-enitols 10:344,345 30-Alkylphenol 21:592 3-Alkylphenols 9:323,329,338,346 3-Alkylpiperidine alkaloids 24:575-579, 581-584,588-605,611-670 monomers of 24:575-579, 594-605 N M R of 24:581-584 polycyclic diamine alkaloids 24:611-662 structures and properties of 24:575-605 Alkylresorcinol 30:159,167 as drug 30:159 Alkylresorcinol molecules 30:163 interaction of 30:163 5-Alkylresorcinols 21:592 Alkylresorcinols 9:328,338 6-Alkylsalicylic acids 21:592 (S)-4- Alkylthiazolidin-2- thio ne derivative 12:164-168 Alkyl-type phosphoramides 14:286 Alkylxanthates 8:316 Alkyl-13-D-glucopyranosides 7:52 Alkyl-[3-D-glucosides 7:50,51,104,105 o~-Alkyl-[3-hydroxyproline moiety 28:367 construction of 28:367 Alkynols 2:14-16 Alkynyl alcohol 12:2413Alkynyl Grignard reagents 6:448 reaction with 1-methoxycarbonyl pyridinium chloride 6:448 reaction with 2-methylpyridinium salts 6:429 Allamandicin 16:299 antifungal activity of 16:299 antileukemic activity of 16:299 antimicrobial activity of 16:299 cytotoxic activity of 16:299 Allamdin 16:299 antifungal activity of 16:299 antileukemic activity of 16:299 cytotoxic activity of 16:299 Allele 30:376 Allelochemical 9:387,21:107 Allelochemical alkaloids 21:103
24 Allelopathic activities 20:391 ;21:109; 24:845;28:483 of natural podolactones 28:484 of synthetic podolactones 28:484 Allelopathic activity 21:109;28:483 of natural podolactones 28:484 of synthetic podolactones 28:484 Allelopathic agent 26:187 Allelopathic interactions 27:214-218 of Agropyron repens L. 27:216 ofAvenafatua L. 27:215 ofAvena sativa 27:216 of Avena strigosa L. 27:215 of Lactuca sativa L. 27:215 of Secale cereale L. 27:125,216 of Taraxacum officinale Wigg. 27:215 of Triticum aestivum L. 27:215 of Zea mays 27:215 Allelopathy 24:867;25:658 bioassay of 24:867 Allene 5:370 Allene epoxide 8:36 rearrangement of 8:36 [3-Allenic amides 21:386 Allenylindium 30:19 Allenyltin 12:170,172 Allenylzinc reagents 30:19 Allergenic dermatitis 2:277,280-281 Allergenic property 30:157 of anacardic acid 30:157 Allergenicity problems 27:315 of Stevia 27:315 of stevioside 27:315 Allergen-specifc IgE 30:773 Allergen-specific Th2 response 30:776 Allergic encephalomyelitis 21:135 Allergic inflammation 30:55 role of natural products in 30:55 Allergic inflammatory disease 30:69 use of Scutellaria baicalensis in 30:69 Allergic reactions 30:773 Allergy inhibitors 5:759 Allergy processes 30:225 role of leukotrienes in 30:225 Allescheria boydii 26:227 Allicin 26:493
Alliin 23:341,457,458,461 formation of 23:461 from S-allyl 7-glutamylcysteine 23:461 Alliinlyase 23:457 Allium ascalonicum L. 22:511 Allium cepa L. 22:511 ;29:341,578, 580,589 for epilepsy 22:511 for epilepsy and infantile convulsions 22:511 Allium macrostemon 21:670 furostanolglycoside from 21:670 Allium sativum L. 22:511,29:684; 23:341,455,481;26:493,796,1135; 28:415 for convulsive affections 22:511 Allium ursinum 29:595,684 (+)-alloaromadendrane-4,10-diol from 14:379 Alliums 23:469 Allocolchicine analogues 29:378 allocolchicinoids total synthesis of 29:378 Allocolchicinoid synthesis 29:364 for biological screening 29:366 from colchicine 29:364 role of colchicine tropolone ring in 29:3 <4 Schmidt ,earrangement in 29:365 to prodrug of N-acetylcolchinol 29:366 Allocolchicinoids 29:356 allocolchiceine as 29:365 (-)-androbiphenyline as 29:358 colchibiphenyline as 29:358 dibenzocycloheptylamines as 29:358 N-acetylcolchinol as 29:365 effects on tumour vasculature 29:366 in clinical trials 29:366 SAR studies of 29:359,365 semi-synthetic analogues of 29:359 synthetic analogues of 29:359 X-ray analysis of 29:359
25 Allocolchicinoids total synthesis 29:373,379 by Banwell 29:377,378 by Boy~ and Brossi 29:378 by Cook 29:375 by Rapoport 29:374 by Wulff 29:379 intramolecular oxidative biaryl coupling in 29:376 of (-)-N-acetylcolchinol methyl ether 29:375 of (+)-colchinol methyl ether 29:374 of (+)-jerusalemine 29:377 of (+)-N-acetylcolchinol 29:376 of allocolchicine analogues 29:378 ofcolchinol analogue 29:378 of positional isomers 29:378 phenanthrene ring enlargement in 29:374 stereocontrolled approach to 29:379 (+)-Allokainic acid 26:478 Allolobophora sp. 30:828 from Lumbricidae family 30:828 (+)-Allomatrine 30:205 activation of kappa-opioid receptors by 30:205 activity in acid-induced abdominal contraction test 30:205 antinociceptive effect of 30:205 SAR of 30:205 Allomelanin 9:231 D-Allomethylpyranose 15:190 Allomones 8:219,220 Allomyces macrogynus 5:276,6:544 Allomyces sp. 5:276 Alloporin 30:533 (+)-Allopumiliotoxins 19:60,61-63,65 Allopumiliotoxin 267 A N-oxide 12:294 from Dendrobates speciosus 12:294 Allopurinol 26:793 Allopylus africanus 22:511 for convulsions 22:511 Allosecurinine 14:657 Allosedamine 10:677
(+)-Allosedamine 13:474 (-)-Allosedamine 13:475,477 Allosorelline 11:320 Alloxan 26:759 (3R,3R')-Alloxanthin 6:153 Alloxanthin 6:154,155 (-)-Alloyohimban 10:155;18:384 Alloyohimbane 25:5,20 All-trans procyanidin dimer B3 21:522 Allyl 2,3-O-benzyl-4-O-tert-butyldimethylsilyl-c~-L-rhamnopyranoside 8:368 Allyl 3,5-O-isopropylidene-2-O-triflyl[3-D-lyxofuranoside 8:330 Allyl acetates 4:21,49 isomerization of 4:49 allylation of 4:21 ~-Allyl complexes 4:398 S-Allyl cysteine sulfoxide 23:461 Allyl ether 1:453 isomerization to vinyl ether 1:453 Allyl formate-induced liver injury 25:466 Allyl glycidyl ether 10:588,589 cyclization of 10:588,589 oxetane ring formation by 10:588,589 ct-Allyl glycosides 10:348 by anti S N 2 displacement 10:348 from D-glucal triacetate 10:419 Allyl isocyanide 12:113 from allyl iodide 12:113 from silver cyanide 12:113 Allyl manganese reagent 4:34,344 S-Allyl mercaptocysteine (SAMC) 23:463,468,472 Allyl methanethiosulfinate 23:467 ~-Allyl palladium complex 4:500; 10:214,215 ~l-Allyl Pd alkylation 10:10-13 intramolecular 10:10-13 Allyl sulfones 3:23 addition to enones 3:23 Allyl sulfoxide anions 3:21,22,435 addition to enones 3:21,22 synthesis of 3:435
26
Allyl thiosulfinate 23:459 Allyl trans-1-propenyl thiosulfinate 23:459 Allyl tributylstannane 12:425,426 S-Allyl-T-glutamylcysteine 23:461 N,N-Allyl,c~-methyl benzylamine 8:403-404 (E)-Allyl- 1-propenyl thiosulfinate 23:467 (-)-5-Allyl-4-methoxy-2-oxazolidinone 12:419 (4R,5R)-5-Allyl-4-methoxy-2oxazolidinone 12:431,432 (4S,5S)-5-Allyl-4-metho xy-2oxazolidinone 12:432,433 (3S,4S)-cyclohexylstatine from 12:432,433 (3S,4S)-statine from 12:432,433 Allyl-9-BBN 14:482 Allylamines 12:411,414;22:58,60,63 2-amino alcohol by 12:411,414 cyclocarbamations 12:411,414 Allylamines Allylation 1:604-610;24:198 diastereoselective 1:604-610 of 2-acetylcyclohexanone 10:412 of FAMSO 6:315,316 with allyl acetate 10:412 Allylation reaction 12:484,14:474; 30:452 stereochemical outcome of 30:452 O-Allylation-Claisen rearrangement 12:269 Allylboration 8:477,478 Allylboronate 1:311,312 stereoselective addition to glyceraldehyde 1:311,312 zt-Allylcation complex 3:82,83 Allylcerium 8:24 Allylchromium reagent 30:24 Allylchromium species 3:81 coupling with carbonyls 3:81 medium ring compounds from 3:81 [3-Allyldiisopinocamphenylborane 19:14 C-Allylfuranoside 3:215
ot-Allylglucosides 3:214,215 synthesis of 3:214,215 (S)-Allylglycine 13:512 Allylic acetoxylation 16:420 Allylic alcohol 12:46,47 allylic aldehyde from 12:46,47 amides from 14:722,723 asymmetric cyclopropanation of 14:490,491 biomimetic cyclization of 14:717-720 by Claisen rearrangement 14:722,723 epoxidation of 10:39,40 2,3-epoxy alcohol from 14:570 from (R,R)-2,3-butanediol 14:490 from acetylenic ketone 11:424 from D-glucose 10:428-438 from dimethyl -tartrate 11:267,268 Johnson-Claisen rearrangement of 10:428-438 mesylation of 4:172,173 one-carbon homologation 3:238 oxidation of 12:46,47,16:594 preparation of 11:424 Sharpless epoxidation of 14:570 transformation of 30:20 with MnO2 12:46,47 with VO (acac)2-TBHP 10:39,40 Z-Allylic alcohols 4:203 cis-hydroxylation of 4:203 Allylic bromination 6:207 Allylic carbocation 4:172-174 asymmetric epoxidation of 4:172-174 Allylic carboxyl group 3:487 phytochemical removal of 3:487 Allylic C-O bond cleavage 1:557,558 with dissolving lithium/amine reduction 1:557,558 Allylic displacement reactions 16:397 palladium catalyzed 16:397 Allylic ethers 4:116 hydroboration of 4:116 Allylic glycolate esters 10:437 Ireland-Claisen rearrangement of 10:437
27 Allylic hydroxylation 1:535;6:200,201 with SeO2/tert-butylhydroperoxide 1:535 Allylic oxidation 3:448;6:126,159,162; 8:197,198;11:11,40,41;12:311; 16:420,669;24:36,37,56-58, 72-74,79,89,90,179,180,186,187 of perezinone 5:722 with Collins reagent 11:83,84 with manganese dioxide 11:356, 357 with SeO2 1:549,550 Allylic polyprenols 8:66,67,72 synthesis of 8:66,67,72 Allylic radicals 4:525 reductive elimination of 4:525 Allylic rearrangement 4:556;6:159; 14:191 ;16:305,617,669 Allylic strain 6:122;14:553 Allylic sulfoxide rearrangement 1:560, 564 Allylic [~-hydroxysulfoxides 4:503,504 stereoselective hydroxylation 4:503,504 Z-Allylic [3-ketosulfoxides 4:509,510 synthesis of 4:509,510 S-Allyl-L-cysteine (SAC) 23:469 Allylmetal additions 8:16 a-Allyloxy anions 3:248-250 [2,3 ]-Wittig rearrangement of 3:248-250 Allylsilane 14:482 Allylstannane 1:247,256,312,313; 10:17-25 Allylsulfenic acid 23:463 Allyltin derivatives 11:442,443 nucleophilic addition by 11:442, 443 Allyltitanium phosphorus reagent 30:17 Allysilane 1:314 Alnus firma 17:359,364 Alnus glutinosa 19:246 Alnus hirsuta 17:360-361 Alnusjaponica 17:360,368 Alnus maximoviczii 26:883 Alnus rubra 17:359,26:596 Alnus serrulatoides 17:359-360 Alnus sp. 17:358-359,368,375
Alnusdiol 17:368;26:895 Alnusone 17:368;26:895 Alnusonal 26:895 Alnusonol 17:368 Alnusoxide 17:368,371 Alocasia macrorrhiza 29:603 Aloe arborescens 30:309 against colon carcinogenesis 30:309 Aloe barbadensis 30:341,412 against coxsackie virus 30:412 Aloe sp. 22:580;30:338 in acute liver injury 30:338 Aloe vera L. 22:511 for epilepsy and convulsions 22:511 Aloe-emodin 30:306 structure of 30:306 Alopecia 21:158 Aloperine 14:754 ent-8-Alpha-hydroxy-lamba- 13,14-dien 25:263 Alpha mannosidase II 22:30 Alpha-bungarotoxin 22:17 Alpha-chaconine 22:36 Alpha-solanine 22:35 Alpha-tomatine 22:32 Alphidium pliciferan 25:895 Alphinia speciosa 21:599 Alphitolic acid 28:62 antimicrobial activity of 28:62 Alpinenone 814 Alpinetin 23:802,808 (+)-Alpinetin 23:821 Alpinia blepharocalyx 26:886,887,902 Alpinia conchigera 26:883 Alpinia galanga 23:800,24:302, 25:257,260 Alpinia katsumadai 17:362,375 Alpinia officinarum 17:362-363,375, 26:883 Alpinia oxyphylla 17:362,375,379, 24:273 Alpinia sieboldiana 17:362 Alpinia sp. 17:358;26:905 Alpiniol 23:812 Alpinmetin 23:808 Alpinolide 23:813 synthesis of 23:813
28 Alpinone 22:473 Alrestatin 22:166,171 Alsidium corallinum 26:479 Alsidium helminthocorton 26:478 Alstocraline 13:395 Alstonia augustifolia 13:422 Alstonia boonei 22:512,29:574,583, 585,587 Alstonia constricta 1:125,214-217,219, 2:369 Alstonia macrophylla 5:135,154-157 Alstonia scholaris R. Br. 5:135,137, 138,13:383 ;22:512 for epilepsy 22:512 Alstonia venenata R. Br. 1:125;22:512, 519 for epilepsy 22:512 Alstonine 1:125;26:1060 Alstopicralamine 9:185,186 Alstovine 1:36 Altenaria kikuchiana 22:273 Altermaria mali 12:400 Alternaria alternata 21:217;22:263; 24:936;25:305,307,672;26:451; 27:793;28:114 diketopiperazines from 24:936 Alternaria cinerariae 11:194 dehydrocurvularin by 11:194 Alternaria helianthi 26:1091 Alternaria kikuchiana tanaka 5:598; 15:385 Alternaria longipes 28:114 Alternaria solani 15:346;25:302,303, 307,316 Alternaria sp. 9:203 Alternaria tenuis 9:300;28:114 Alternatamide A 25:774 Alternatamide B 25:774 Alternatamide C 25:774 Alternosides I-V 27:41,44,45 as sweetness inhibitors 27:41 structures of 27:41,45 Alteromonas luteoviolaceus 21:298 Alteromonas rawa 25:820 Alteromonas sp. 21:411,259;25:717,719 alteramide A from 21:411 Altertogorgia sp. 25:695 (+)-Altholactone 19:468
Altholactone 19:498 biological activity of 19:498 Altholactone (goniothalenol) 9:393 Altohyrtin 25:761 Altohyrtin A 25:727 Aluminium hydride 3:474 selective reduction with 3:474 Alutera scripta 5:390 Alvaxanthone 28:229 biological activity of 28:229 Alycoprotein-rich substance (CVS) 30:776 against experimental metastasis 30:776 antitumor effect of 30:776 Alysine B 634 Alysine C 23:634 Alysine D 23:634 Alzheimer dementia progression 21:585 Alzheimer's diseases 14:637;21:748, 749;22:343 ;30:504 (-)-physostigmine for 14:637 Alzheimer's disease therapy 25:530, 536,710 Amadori rearrangement 18:680 Amalan 26:140 Amalgam procedure 14:746 Amalhia alternata 25:776 Amaloride acetate 23:31511Amanatdine 24:489 dmanita agaricus 9:203 Amanita muscaria 22:737;23:115,118, 134;29:292 Amanita phalloides 5:496;21:96 Amantadine 27:108 for treatment of influenza A 27:108 Amaranthus caudatus L. 27:217;29:607 dmaranthus hypochondrionacus 29:607 Amaranthus retroflexus L. 27:217 Amarathine 26:305 Amariin (hydrolysable tannin) 29:572 effects on HIV- 1 protease 29:572 Amarillidaceae alkaloid 25:536 galanthamine (galantamine) 25:536 Amarogentin 7:490;26:806,807 Amaroswerin 7:490
29 Amarouciaxanthin A 6:136,142 Amarouciaxanthin B 6:151,152 Amaryllidaceae 22:29 Amaryllidaceae alkaloids 22:5; 26:608-613,615-620 Amastatin [(2S,3R)-3-amino-2-hydroxy5-methylhexanoyl-L-valyl-L-valylL-aspartic acid)] 12:434 leucine aminopeptidase inhibitor of 12:434 Amata sp. 5:225,252 Amathamides C,D,E and F 18:715 Amathaspiramide E 25:782 Amathia alternata 17:85 Amathia convoluta 17:75,18:715; 25:786 Amathia genus 17:82 Amathia wilsoni 17:92,95,97,101; 18:693;25:782 Amaurornis phoenicurus 5:83 hemoglobin components of 5:83 Amberlite IR-45 15:460 Amberlite IRA-400 12:317 Ambigol A 25:792 Ambigol B 23:342;25:792 Ambliofturan 25:688 Amblyomma americanum 25:795 Amblyomma hebraeum 28:396 Amblyomma sp. 28:394,397 Amblyomma variegatum 28:395 repellent properties of 28:395 Ambrosanolide 16:140;29:90 activity in EPP assay system 29:90 Ambrosia maritima 7:427 Ambrosia peruviana 14:379 Ambrosia sp. 25:138;26:437 Ambrox 25:253;26:394 Amenanthus retroflexus 7:398 Amentoflavone 22:429;25:545 Amentoflavone (3',8"-biapigenin) (biflavone) 29:578 effects on ACE 29:578 American trypanosomiasis (Chagas disease) 26:784,798 Americanol A 26:270 Americanolide A 23:161 Americanolide B 23:160 Americanolide C 23:161
Americanolide D 23:161 Americanolide E 23:161 Americanolide F 23:161 Amerlyst A-21 19:131 Ames test 22:682;27:303,304 AMI calculations 30:542 AMI molecular orbital 22:599 AMI molecular orbital calculations 30:541 Amicetin 4:234,240,242 Amicoumacin A, B and C 15:388 Amide cyclisation 4:546 Amidiol (taraxast-20(30)-ene-3 [3,16[3diol) (triterpene) 29:585 against bacterial diseases of rice plants 29:480 as neuraminidase inhibitors 29:464 biological profile of 29:480 effects on CHY 29:585 effects on glycosidase enzyme 29:480 in structure-based drug discovery 29:464 Amidoalkylation 10:108 intramolecular 10:108 Amidoalkylation reagents (Nacyliminium ions) 13:473-518 Amidocarbonylation 16:408 Amidocyclization 1:382 Amiloride-binding proteins 26:1268 Amination 6:429;16:438 intramolecular 6:429;16:438 Amines 6:429 formation from ketones 6:429 photosensitized oxidation of 16:604 reductive animation of 6:429 D-allo-~-Amino acid 11:460,461 synthesis of 11:460,461 L-allo-c~-Amino acid 11:460,461 synthesis of 11:460,461 (x-Amino acid 12:115,435-438 as chiral building blocks 1:678-684 by hetero Diels-Alder adducts 12:435,436 conversion to amino sugars
30 4:111-156. synthesis of 12:435-438 Amino acid 16:395-414,604;23:234; 24:799 as chiral synthons 4:625 by a-halo boronic ester 11:417-420 non-protein 24:779 photooxidation of 16:604 simple derivatives of 23:234 synthesis of 11:417-420, 13:507-516,16:395-414 Amino acid decarboxylase (AADC) 30:384 Amino acid pathway 21:213 metabolites derived from 21:213 D-Amino acids 12:158,159 by hetero-Diels Alder reaction 12:158,159 cyclization by UGl-reaction 12:116 cyclization of 12:115,116 D-lactams from 12:115 synthesis of 12:155,158,159 (x-Amino acids/esters 1:331-338 conversion to azomethine ylides 1:331-338 decarboxylation of 1:331-336, 337 imines from 1:331 Amino acrylic acid 23:463 Amino acylase 1:678-680 for synthesis of c~-amino acids 1:678-680 Amino alcohol 11:298,299 benzyl-protected 11:298,299 with aldehyde 11:298,299 2-Amino alcohols 12:411,414 by aldol reaction 12:411,414 by cyclocarbamation 12:411,413 by electrophilic addition 12:411, 414 by Michael reaction 12:411,413 by nucleophilic addition 12:411, 413,414 by oxyaminations 12:411,414 by reduction 12:411,414 by ring-opening of oxirane
12:411,413 from 2-oxazolone 12:411-444 synthesis of 12:411-444 a-Amino aldehydes 12:411,414 2-amino alcohol by 12:411,414 in [4+2] cycloaddition 4:111 in Diels-Alder reaction 4:120 metalloorganic addition to 4:124 N,N-diprotected 4:124 nucleophilic addition of 12:411, 414 preparation of 4:113,114 N, O-protected 4:130 ?'-Amino butyric acid 25:548 y-Amino butyric acid (GABA) 25:517, 519,520 e-Amino caproic acid (e-ACA) 30:836, 844 Amino carbonylation 14:568 intramolecular 14:568 palladium (2+) catalyzed 14:568 a-Amino ketones 12:411,414 2-amino alcohol by 12:411,414 reduction of 12:411,414 steroid-pyrazine dimers via 18:885-887 Amino sugars 4:115-118 synthesis from glycine 4:115-118 synthesis of 13:190-207 4-Amino- 1",6"-anhydro-2",3 ",2',3', 6', 2,3-hept-O-benzyl-4,6- dideoxy-[3maltotriose 10:508,509 2-Amino- 1,3-azulenedicarboxylate 14:339 2-Amino- 1,4-benzoquinone-3carboxylic acid 26:995 2-Amino-2,3-di-deoxyhexoses 14:145 5'-([(Z)-4-Amino-2-butenyl]-methylamino)-5'deoxyadennosine 26:830 2-Amino-2-deoxy-D-galacto-Dgalactans 5:298 2-Amino-2-deoxy-D-glucose 1:512 2-Amino-3,6-dihydroxy-benzoic acid 26:979 2-Amino- 3- [5-deoxy- 5-(dimethylassinoy)-/3-D-[ribofuranosyloxy]-2-
31
hydroxy-propene- 1-sulfonic acid 25:867 1 -(4'-Amino-3 '-bulte nal- 2 '- yl)- [3carboline 26:1087 3-Amino-3-deoxy-D-mannose 12:314 3-Amino-3-deoxynucleosides 4:240 synthesis of 4:240 3-Amino-3-deoxysugars 4:150 synthesis of 4:150 a-Amino-3-hydroxy-5-methyl-4isoxazole prionic acid (AMPA) 25:529 2-Amino-3-hydroxy-benzoic acid 26:972 2-Amino-3-hydroxycyclopenten-2-one 21:398,405,409 20-Amino-3-hydroxycyclopenten-2-one 21:405 2-Amino-3-phenoxazionone 26:986 2-Amino-4,4-a-dihydro-4 a, 7-dime thyl3H-phenoxazin-3-one 26:986 4-Amino-4-deoxy-D-mannose 12:314 1-Amino-4-methylpiperazine 23:59 2-Amino-5-[(2'-carboxy-6'-hydroxy phenyl)-amino]- 1,4-benzoquinone-3carboxylic acid 26:977 2-Amino- 5a -deoxy-a-D L-glucopyranose 13:203 Amino-5-hydroxybenzioc acid (AHBA) 23:79 Amino-5-hydroxybenzoic acid 21:42133-Amino-5-hydroxyl-coenzyme A 23:89 2-Amino-5-nitrotoluene 13:442 6-Amino-6-deoxysugars 4:111,127 from a-amino acids 4:111,127 6-Amino-6-deoxyuloses 4:124 synthesis of 4:124 2-Amino-6-hydoxy-4-methyl-8-oxodecanoic acid 21:225 5-Amino-7-methoxy-2,2-dimethylchroman 13:358,359 synthesis of 13:358,359 Aminoacyl-tRNA 21:98 (L-a-Aminoadipoly)-L-cysteinyl-Dvaline 8-(LLD ACV) 11:211-213
cephalosporin C from 11:211-213 penicillins from 11:211-213 5'-Aminoalkyl oligonucleotides 4:294, 295 synthesis of 4:294,295 Aminoalkylated oligonucleotides 4:306 Aminoalkylindoles 30:196,197,198 as cannabinoid receptors ligands 30:197 Aminoalkylindoles 30:196,197,198 structure of 30:197 4[3-Aminoaniline 26:162 synthetic derivatives of 26:162 (+)-9-Aminoaporphine 16:516-517 m-Aminobenzoic acid 21:401 p-Aminobenzoic acid 21:401 2-Aminobenzothiazole 26:162 synthetic derivatives of 26:162 p-Aminobenzyl alcohol 21:162 O-Aminobenzylalcohol 18:164 p-Aminobenzylcarbamate 21:169 2-Aminobenzyltetrahydroisoquinoline 18:73 Aminobisabolene 26:1201 a-Aminobutyrate 21:226 ~,-Aminobutyric acid (GABA) 30:782, 784 as inhibitory neurotransmitter 30:782 effects on blood pressure 30:784 effects of 30:784 y-Aminobutyric acid (GABA) 30:782, 784 accumulation of 30:782 9-Aminocamptothecin 13:655 Aminocarbafuranoses 29:462 as building blocks 29:462 diversity-oriented synthesis of 29:463 in structure-based drug discovery 29:464 starting materials for 29:464 Aminocarbapyranoses 29:480 as carbasugars 29:480 as validamine 29:480 naturally occurring 29:480 valienamine-type carbaglycosyl
32 amine as 29:480 valiolamine as 29:480 Aminocholine 24:913 contraction by 24:914 primary structures of 24:913 Aminocoumarins 18:978 Aminocyclitol 13:212,14:147 Aminocyclitol fortamine 4:118 Aminocyclitol inhibitors 10:517-524 (IR, 2S)-2-Aminocyclopentanecarboxylic acid (cis pentacin) 22:273,274 2-Aminocyclopentanecarboxylic acid 22:299 1-Aminocyclopropane- 1-carboxylate (ACC) 25:372 1-Aminocyclopropane- 1-carboxylic acid oxidase 26:935,950 Aminodeoxyhexosyl-purines 4:238-248 synthesis of 4:238-248 Aminodeoxyhexosyl-pyrimidines 4:238-248 synthesis of 4:238-248 9-Aminoellipticine 22:27 Amino-epoxides 12:351 Aminoepoxycyclohexanone 21:399 2-Aminoethanethiol 8:317 2-Aminoethyl phosphonic acid 2:304-309 3-Aminoflavones 27:926 for cytotoxicity 27:926 2-Aminofluorene 8:377,388 Aminoglycopyranoses 7:47 [3-glactosidase inhibition with 7:47 Aminoglycoside antibiotics 22:58 Aminohexose derivatives 1:25-27 synthesis of 1:25-27 Aminoimidazole 21:270;23:257 2-Aminoindan-2-phosphonic acid (AIP) 25:674 5-Aminolevulinic acid 21:398 5-Aminolevulinic acid (ALA) 9:591, 593,601,603,606 Aminolysis 12:279 intramolecular 12:279 of disaccharide lactone 6:407 of MurNAc 8-1actones 6:393 Aminomethyl bilane (AMB) 9:597
a-Aminonitriles 14:716-718 formation of 14:716-718 via Polonovski reaction 14:716-718 2-Aminonucleosides 4:238 fusion reactions for 4:238 synthesis of 4:238,239 6-Aminonucleosides 4:248 4-Aminooctanal diethyl acetal 6:445,447 condensation of 6:445,447 with diethyl-3-oxo-glutarate 6:445,447 with ethanal 6:445,447 5-Aminooligonucleotides 4:294-292 synthesis of 4:294-292 2-Aminooxetanocin A 10:619,620 antiviral activity of 10:619,620 Aminopentanal 14:739 5-Aminopentanol 21:107 Aminopeptidase B 10:629,646,652 p-Aminophenyl- 1,4,4'-trithiocellotrioside 8:344,346 p-Aminophenyl- 1,4-dithiocellobioside 8:351 20c~-Aminopregn-5-en-3 [3-yl- [3-Dglucoside 5:128 2- [3-Aminopropylidene]- 1,3-dithiane 12:335 4-Aminoquinoline compounds 25:343, 345 quinolinemethanol derivatives 25:343 Aminoquinone 5:437 immunosuppressive effect of 5:437 Aminoresorcinol 26:1272,1273 Cu(II)-Aminoresorcinol 26:1273 4-Aminosampangine 23:6 Aminosidine (paromomycin) 26:831 Amino-substituted morphan analogue 30:199 structure of 30:199 7-Amino-substituted Neu5Ac derivatives 30:426 synthesis of 30:426 via azido derivative 30:426 Aminotransferase activity 19:650 Aminotriazole oxidation 4:548
33 4-Aminouncleosides 4:241-247 D-ct-Aminouronic acid 11:459,460 synthesis of 11:459,460 L-c~-Aminouronic acid 11:459,460 synthesis of 11:459,460 6-Aminovalerookadaic acid 5:385,388 o~-Amino-[3-carboxymuconic-~-semialdehyde 26:970 (3 R)-?-Amino-f3-hydroxybutyric acid 12:434 biological activity of 12:434 as central inhibitory transmitter 12:434 4-Aminoquinoline (chloroquine) 26:781 Aminyl radical heterocyclization 1:292 of chloramines 1:292 Amipurimycin 1:398,404-410,4:246, 11:430,433 Amipurimycin 22:273 Amisine 20:234 Amistar 22:250 Amitermes evuncifer 14:452,463 evuncifer ether from 14:452,463 Amitermes excellens 14:450-452 amiteol from 14:450-452 A mitermes messinae 14:452 evuncifer ether from 14:452 Ammania baccifera 9:65 sesquiterpenes from 9:65 Ammanol 9:65 Ammi majus 23:337 Ammi sp. 29:579 Ammi visnaga 23:352;29:571 (+)-Ammodendrine 15:520 Ammodendrine 21:97 Ammonium D- 10-camphor-sulfonate 15:425 Ammonium glycyrrhizin 15:5 Ammonium nitrate 2:412,413 Ammonolysis 16:97,98 with ammoniacal methanol 16:97,98 Ammophila fernaldi 5:224,232,253 Ammophila nigricans 5:224,232,252 Ammophila procera 5:225,232,252 Ammophila urnaria 5:223,224,232,252 Amodiaquin 22:148 Amodiaquine 25:344,348
Amoebicidal activity 6:485;26:458 of emetine 6:485 of 1,2-secoemetine derivatives 6:485 Amoebicides 7:398 Amomum 23:817 Amomum cardomon 24:272 Amomum compactum 24:274 Amomum xanthiodes 24:272 Amoora 21:124 Amopyroquine 25:344 Amorpha fruticosa 24:225,227 Amorphane 15:247;25:848,849 AMOX 28:224 anti-microbial activity of 28:224 Amoxicillin 25:617;26:366 c-AMP phosphodiesterasc inhibitory activity 26:38 of dianchinenoside E and F 26:38 (+)-Ampelopsin A&B 26:551,566 Ampelopsin C&D 26:558,566 cis-Ampelopsin E 26:558,566 trans-Ampelopsin E 26:566 Ampelopsin E-H 26:558,567 Ampelopsis brevipedunculata 26:551 Ampelopsisjaponica 22:512 as anticonvulsive agent 22:512 Ampelosin 25:470 Amphetamine 25:537 as immunosuppressive drug 25:537 Amphetamine 25:537,538 Amphibia 21:3 Amphibian alkaloids 29:433 2,5-disubstituted decahydroquinolines as 29:433 from ants 29:433 from dart poison frogs 29:433 pharmacological activity of 29:433 strutural diversity of 29:433 synthesis of 29:433 Amphicarpa meridiana 23:273,275 Amphicarpeae edgeworthii 25:93 Amphidinium sp. 5:396,19:559 Amphidinolide M 19:566 cytotoxicity of 19:566
34 Amphidinolide Q 19:560 cytotoxicity of 19:560 Amphidinolides 5:396 Amphilectane-type diterpenoids 25:690 Amphimedon complanata 26:90 Amphimedon compressa 21:308 Amphimedon sp. 21:260;25:709,710; 26:454 Amphimedon sponge 26:74,88 Amphimedon terpenensis 21:350-352, 363,367 Amphimic acid A 26:88,89 Amphiphilic triterpenoids 25:541 Amphiscolops sp. 5:396 Amphotericin B 2:421,422,446; 4:513-520;6:261-306;10:150; 17:245 ;21:758;22:58,60,64,248; 26:794,795 Amphotericin B (AmB) 23:343,347,380 Amphoteronolide 10:153,166 Amphoteronolide B 4:573;6:261-276 Amphoteronolide B methyl ester 6:264, 265 Ampicillin 25:258 AMPK phosphorylates 25:525 Ampulliferine thunbergii 21:417 (-)-ampullicin from 21:417 (+)-isoampullicin from 21:417 Amsonia elliptica 1:125 Amti 23:657 Amycolatopsin sp. 28:150 Amygdala 30:375,376,379 effect on dorsal raphe serotonin (5-HT) neurons 30:376 Amylase 6:551,7:32-36,39;10:496-498; 8:343 ;24:995-998;25:719 enzymatic activity of 24:995-998 a-Amylase 7:32-35,10:242,243, 504-507,514,13:195;16:8622:622; 27:330,331 in aleurone protoplasts 27:331 13-Amylase 7:33,58,59,10:497;16:86 ~-Amylase inhibitor 13:189 acarbose as 13:189 Amyloglucosidase 7:13,10:567,357, 14:150 [3-Amyloid 30:837
Amylopectin 7:6,10:496-498 in starch 7:6 Amylose 5:288,291,292,7:6,10:496,497 Amylostatins GXGGG 10:509 inhibitory activity of 10:509 Amylostatins GXG 10:509 inhibitory activity of 10:509 Amylostatins GXGG 10:509 inhibitory activity of 10:509 Amylostatins XG 10:509 inhibitory activity of 10:509 synthesis of 10:507-511 Amylostatins XGG 10:509 inhibitory activity of 10:509 Amylostatins XGGG 10:509 inhibitory activity of 10:509 (x-Amyrenol 29:585 effect on CHY 29:585 effects on HIV- 1 protease 29:574 effects on collagenase 29:583 ~x-Amyrin (ot-amyrenol; viminalol) (ursane triterpene) 21:690;22:108, 119,121,129;23:824;27:589;29:574, 583,585 effects on collagenase 29:583 effect on CHY 29:585 effects on HIV- 1 protease 29:574 ~-Amyrin (ursene triterpene) 23:535, 546,824 ;25:58 ;29:574 ;30:719 effects on HIV- 1 protease 29:574 structure of 30:719 Amyrin 30:206 use in inflammatory skin conditions 30:206 (x-Amyrin acetate 27:589 c~-Amyrin linoleate 29:583 effects on collagenase 29:583 ~-Amyrin linoleate 9:461 (x-Amyrin linoleate ((x-amyrin cis-9.cis12-octadecadienoic acid ester) 29:583,585 effects on CHY 29:585 synthesized from c~-amyrin 29:583 [3-Amyrin palmitate 9:461
35 ot-Amyrin palmitate 29:583 effects on collagenase 29:583 synthesis from c~-amyrin 29:583 Amyris balsamifera 21:583 Anabaena circinalis 26:367 Anabaena cylindrica 25:717 Anabaena doliolum 26:366 Anabaena genera 27:879 Anabaena sp. 25:794;26:352,354,358, 359,364,365,378,379 Anabaena variabilis 26:366 Anabasine 21:51,97,110 Anabsin (guaine sesquiterpene dimer) 7:239;29:574 effects on HIV- 1 protease 29:574 Anabsinthin 7:239 Anabsinthin (guaine sesquiterpene dimer) 7:239;29:574 effects on HIV-1 protease 29:574 (15:0)-Anacardic acid (2-hydroxy-6pentadecyl benzoic acid) 9:314,316, 345,346,356 Anacardic acid 11 (Z)-diene 30:144 synthesis of 30:144 Anacardic acid 8(E)-monoene 30:143 by trans elimination reaction 30:143 Anacardic acid 8(Z)-diene 30:144 synthesis of 30:144 Anacardic acids 5:824-831 ;9:313,315, 316,328,330,331,333-341,346,349, 355,358,361-368,370,371 ;21:590, 591,592 ;24:297,298;30:147-148 synthesis of 30:147-148 Anacardic aldehyde 9:341 Anacardium giganteum 9:316 Anacardium occidentale 7:427,17:645; 9:75,316,318,323,329,332,335,337, 338,340,347;21:591 Anacardium semecarpus 9:318 Anacyclus 29:683 Anacyclus pyrethrum 10:162;21:378, 379;24:686,690,705,708, 710,712 anacyclin from 21:378 pellitorine from 10:162;21:378 Anaerobiosis 9:565,572 Anaesthetic activity 21:378
Anagallis arvensis L. 22:512 for epilepsy 22:512 Anagallis arvensis L. 22:512 for epilepsy and hysteria 22:512 Anagasta kueniella 9:322 Anagyrine 21:97 (-)-Anagyrine 26:487 Anagyrine 27:276 structure of 27:276 Anagyris foetida 27:278 Analeptic 30:72 Angelica keiskei use as 30:72 Analgesia 30:200,799,800,801 by 8-opioid receptor activation 30:801 by opioid 30:799 in mice 30:800 role of delta opioid receptor in 30:799 role of mu-opioid receptors in 30:799 Analgesic 17:633;30:193,194,204,799 alkaloid 30:799 use of Cannabis sativa L. as 30:194 use of Dispsacus asper as 30:204 use of Papaver somniferum as 30:193 Analgesic action 30:193 of olvanil 30:193 of ricinoleiic acid 30:193 of triphenyl phenol scutigeral 30:193 analgesic activites of 29:420 anesthetic activities of 29:420 antibiotic activities of 29:420 Analgesic activity 21:595,673 ;23:153, 180;26:32,56;30:195,198-201,817 ofbarbatosides A and B 26:56 of cembranes 23:180 ofdianosides A-1 26:32 of DPDPE 30:817 of enkephalyn 30:817 of kallilolides 23:180 of opioids 30:198-201 of pseudopterolides 23:180 ofpseudopterosins 23:153, 158,180
36 of secopseudopterosins 23:180 structure-activity relationships (SAR) 30:198 Analgesic alkaloid 30:799 addiction due to 30:799 for acute pain 30:799 gastrointestinal depression due to 30:799 respiratory depression due to 30:799 side effects of 30:799 tolerance due to 30:799 Analgesic characteristics 30:817 Analgesic drug 30:191,192,203 development of 30:192,203 use of 30:191 Analgesic effects 26:401,403,404,406, 416,418;30:205,208 by K + channel modulations 30:208 in thermal models of nociception 30:205 of furosin 30:208 of gallic acid 30:208 of geraniin 30:208 of Phyllanthus genus 30:208 of quercetin 30:208 of rutin 30:208 of stigmasterol 30:208 Analgesic mechanism 30:193 Analgesic potencies 30:800,813 ofopioid analogues 30:800,813 Analgesic properties 30:207 of menthol 30:207 Analgesics 30:191 in pain treatment 30:191 natural products as 30:191 Analgesics/antipyretics 30:192 acetaminophen as 30:192 dipyrone as 30:192 Analogs 27:336-337 conformational property of 27:337 Ananas comosus 27:872;29:600 Anandamide 30:195,196 as endogenous cannabinoid 30:195 effects on tetrahydrocannabinol 30:195
fluorine analogue of 30:196 pharmacological properties of 30:195 SAR of 30:196 Anandamide analogues 30:196 molecular field analysis of 30:196 Anandamide endocannabinoids 30:196198 structure of 30:197 Anaplastic carcinoma 26:712 Anas platyrhynchos 5:836 hemoglobin components of 5:836 Anaxagorea luzonensis 28:234 Anchinoe tenacior 25:862;28:715 Anchusa officinalis 17:126 Anchusa strigosa 29:571 Ancistrocerus antilope 5:223,232,253 Ancistrocerus campestris 5:224,252 Ancistrocerus sp. 5:251 Ancistrocladidine 20:408,433,434,437 Ancistrocladine 20,408,419,420,422, 423,431 Ancistrocladus abbreviatus 20:447 ancistrobrevin B from 20:447 Ancistrocladus alkaloids 20:408,437 Ancistrocladus heyneanus 26:813 Ancistrocladus korupensis 20:442,447; 26:822;27:865 korupensamines A and B 20:442 korupensamines C 20:447 michellamines from 20:442 Ancistrocline 20:408,424,425 Ancistrocongine 20:276 Ancorina sp. 28:120 Ancylostoma 26:481 Ancylostoma duodenale 26:425,429 Andalusol 25:249,250;29:102 activity in ACM bioassay system 29:102 activity in CRG bioassay system 29:102 activity in NFkB bioassay system 29:102 activity in NO bioassay system 29:102 activity in TPA bioassay system 29:102
37 Anderson & Bridgeman study 27:511 of proteinaceous polysaccharides 27:511 trans Anethole 27:16,33 structure of 27:33 Andrastins 24:452,453 FPTase inhibition by 24:403-464 Andrena haemorrhoa 19:129,131-132 Andrena ocreata 19:129 Andrena ovatula 19:129 Andrena wilkella 1:692;19:129 mandibular gland secretion 1:692 Andrimid 21:296 Androctonin 23:341 Androctonus australis 23:341 Androcymbium palaestinum 29:358 Andrographis paniculata 5:678,7:117, 17:472;24:275;25:251,270;29:102, 586-588 Andrographolide 29:102 activity in AOS bioassay system 29:102 activity in iNOS bioassay system 29:102 activity in NO bioassay system 29:102 Andropogon zizanioides 24:274 Androsace saxifragifolia 15:200 saxifragifolins A and B from 15:200 Androsaemum 30:609,610 Androst-l,4-diene-3,17-dione 9:411 Androst-4-ene-3,17-dione 9:15-17 Androstanolone 18:885 6,(5o0-Androstene-3,17-dione 8:188 Aneilema scapiflorum 22:512 for infantile convulsions 22:512 Anemarrhena asphodeloides 21:668, 670;24:919-922;26:237 ;28:234 in diabetic treatment 24:919 pseudoprototimosaponin AIII from 21:668 prototimosaponin AIII from 21:665 steroidal saponin from 21:670 Anemia mexicana 6:195,202,208 antheridiogens from 6:195,202, 208
Anemia phyllitidis 6:194,202 antheridiogen from 6:194,202 Anencephaly 23:571 Anethofuran 29:83 activity in GST assay system 29:83 Anethol 13:334-337 Anethole 21:599 trans-Anethole 5:473,13:332,15:29 Anethum graveolens L. 7:108,109; 27:379;29:83 Anethum sp. 29:581,582 Aneuploidogen diethylstilbestrol 26:271 ANF-activated membrane bound guanylate cyclase 25:523 Angelaud and Landais 29:467 carbaaldopyranoses synthesis by 29:467 Angelica archangelica 23:350 Angelica decursiva 23:352;27:835 Angelica furcijuga 25:471,476 Angelica gigas 27:835 Angelica keiskei 22:432,29:578,775; 30:55,56 from 22:4-hydroxyderricin chalcones from 30:56 inhibition of catecholamineinduced vasoconstriction by 30:55 use as analeptic 30:72 use as diuretic 30:72 use as lactagogue 30:72 use as laxative 30:72 use in catecholamine-induced vasoconstriction 30:72 use in coronary heart diseases 30:72 use in hypertension 30:72 xanthcangelel from 30:55 Angelica pubescens 26:436 Angelica shikokiana 27:429 Angelicin 22:539,522;23:337,338 Angeloyl oxyestafiatin 27:5778aAngeloylajadin 27:575 Angeloylcumambrin 27:577 Angeloylgomisin H 26:197,247 8c~-Angeloyloxy- 1[3-peroxy costunolide 27:560
38 8cx-Angeloyloxy-cosmnolide 20:471; 27:559 Angiogenesis 26:757;30:56,61-64 by fibroblast growth factor 30:56 by matrigel 30:56 effect of matrigel/VEGF/heparin mixture 30:61 effect of triterpenoids on 30:61, 62 in vivo 30:61 inhibition by carp oil 30:69 Angiogenesis inhibition 24:888-890 by magnosalin 24:888-890 Angiogenesis inhibitor 22:262 Angiogenesis inhibitory activity 24:406 Angiogenic response 30:61 role of heparin 30:61 Angiosperms 9:265 Angiostatic activity 21:435 AngiostrongTlus 26:484 Angiotensin II-induced hypertension 25:595 Angiotensin-II 26:267 Anguibactin 25:877 Anguillosporal 22:72 Anguillula aceti 26:450,452,459,464, 482 Anguina tritici 26:456 Angularly fused tricyclic framework 29:129 stTucmres with 29:128 Angulatin A 23:667 Angulatueoid G 23:667 Angusticraline 13:394 Angustiicine 1:36 Angustine 3:405,5:85,126 Angustone B 28:228 biological activity of 28:228 (-)-Anhalonine 2:163 2,7-Anhydro sugar analogue 30:463 14,15-Anhydro- 1,2-dihydrocapuronidine 5:125 1,6-Anhydro-2,4-di-O-benzyl-3-O(tertbutyl-di-methyl silyl)-[3-Dglucose 14:255 1,6-Anhydro-2-O-b enzoyl-3,4-di- Obenzyl-[3-D-galactopyranose 14:256
1,2-Anhydro-3,4:5,6-di- O-isopropylidene-D-mannitol 30:439 reaction of 30:439 2,3-Anhydro-4,6-O-benzylidene-~-Dtalopyranoside 14:167 1,6-Anhydro-4-deoxy-L-ribopyranose 14:255 2,3-Anhydro-allo-hexopyranoside 14:149 Anhydroalstonatine 1:125,126 Anhydroamarouciaxanthin B 6:151,152 Anhydroascorbic acid 4:718 Anhydroaustricin 7:236 14,15-Anhydrocapuronidine 5:125 2',3'-Anhydrocyclitol glycoside 14:147 Anhydrodeacyltautomycin 18:271,284 Anhydrodihydroartemisinin 22:154 Anhydrodimers 7:136,137 Anhydroerythromycin A 13:158 1,5-Anhydro-galactitol 7:65 1,6-Anhydro-galactose 7:65 Anhydrogrossmisin 7:236 Anhydromacrosalhine-methine 13:396, 397 l',6'-Anhydromaltose 10:507,510,511 l",6"-Anhydromaltotriose 10:507 Anhydroperoxisomicine-quinone-A ~ (T510) 22:570 Anhydrophlegamacine-9,10-quinone A2 22:580 Anhydrophlegamacine-9,10-quinone B2 22:580 E-Anhydropodorhizol 5:486 Anhydropodorhizol (nemorosin) 5:484488 Anhydroschumannificine 21:145 1,4-Anhydrosorbitol 12:29,30 16,17-Anhydrotacamine 5:126,9:179 Anhydrotaxininol 12:216 15(28)-Anhydrothyrisiferyl diacetate 5:363 Anhydroverlotorin-4c~,5 ~-epoxide 27:572 c~-3',4'-Anhydrovinblastine 27:780-783 c~-Anhydrovinblastine 27:782 Anhydrovinblastine Nb-oxide 14:812, 813
39 15'c~-hydroxyleurosidine from 14:812,813 15'-hydroxy-3'-oxoleurosidine from 14:812,813 5'-nor and 5',6'-seco derivatives of 14:872 3'-oxoanhydrovinblastime from 14:812,813 Polonovski reaction of 14:872 Anhydrovincristine 14:818,819 from anhydrovinblastine 14:818,819 Anhydrovobasindiol 5:123,9:171, 15:469 19(Z)-Anhydrovobasinediol 15:466, 467,491 3,4-Anhydro-cx-D-altropyranoside 14:170 1,6-Anhydro- [3,D-glucopyranose 6:287, 288 3,4-Anhydro-[3-D-galactopyranoside 14:170 1,6-Anhydro-[3-D-glucose 10:425 Aniba sp. 8:159 neolignans from 8:159 Aniba canellila 19:117 Aniba neolignans 8:159-163 Anigopreissin A 26:566 Anigozanthos sp. 17:372 Anilido 4:286 as protecting group 4:286 Anilidopiperidines 30:200 in central analgesic activity 30:200 8-Anilino- 1-naphthalenesulphonic acid 9:453 4-Anilinosampangine 23:6 Animal models with osteoporosis 30:499 effect of 1c~,25(OH)2D4 on 30:499 Animal product 24:904-916 effect on cardiovascular arrythmia 24:904 Animals 26:221 ;26:943 metastatic secondary tumor in 26:221
NO-mediated apoptosis in 26:943 Anion exchange 4:282,283 for oligonucleotide purification 4:283 in HPLC 4:282,283 Anion mediated alkylation 8:229 of difunctional acyclic terpenoids 8:229 Anion radicals 30:549 dimerisation of 30:549 [3,3]Anion radicals 30:549 dimerisation of 30:549 Anionic oxy-Claisen 12:93 Anionic oxy-Cope rearrangement 3:77, 78 eight-membered rings by 3:77,78 Anionic pinacol rearrangement 14:360 Anionic polysaccharide (PS) 30:401 Anisakis sp. 26:475 larvae of 26:457,474,475 Anisodine 21:56 Anisomycin 14:568 Di-p-Anisylmethylamine 12:152 Ankinomycin 11:136 Ankyrin 25:496 Annelation 19:227;24:203 ofresorcinol 19:227 of substituted phenol 19:227 regiospecific 19:227 Annelation reaction 14:694,695 Annelid worm 30:832 serine protease from 30:832 Annoba montana 26:212,243 syringaresinol from 26:212 (-)-syringaresinol from 26:243 Annona bullata 9:396,397;18:221 Annona densicoma 9:395 annonacin from 9:395 Annona glabra seeds 28:430 acetogenins from 28:430 against Dermatophagoides pteronyssinus 28:430 against Typhlodromus urticae 28:430 Annona muricata L. 17:277;18:213 22:512 for epilepsy convulsive seizures 22:512
40 Annona squamosa 9:398;28:404,415 extract of 28:415 Annonaceae 21:611;25:249 Annonaceous acetogenins 17:251-286; 28:437 as complex I inhibitor 28:436, 437 Annonacin 9:395,396;17:266,272,279; 26:441 tetraacetate of 26:441 Annonacin A 17:267 Annonacin- 10-one 17:272 Annonacinone 26:441 Annonaine 25:53 Annonidium monni 22:512 for epilepsy 22:512 Annonin 26:441 Annonin I 17:252 Annotinine 18:341 13,16-Annulated oxathiaphospholane 8:126,127 2[3,313-Annulated oxathiaphospholane 8:126,127 [4+ 1]-Annulation 3:40-45 triquinane synthesis by 3:40-45 [2+3]-Annulation 3:7 annulation methods 3:7 for five-membered rings 3:7 of aldehydes 3:5-58 triquinane synthesis by 3:47,48 [4+4]-Annulation 3:78 Danheiser version 3:78 for 8-membered ring synthesis 3:78-79 intermolecular 3:78 nickel catalysed intramolecular 3:78 Annulation 6:5 by Simmons-Smith reaction 6:5 intramolecular 10:407 of 1 methyl-2-tetralone 14:670,671 of c~-diazo-[3-keto ester 10:407 of cyclohexane ring system 6:5,6,29,30 of cyclopentane ring system 6:6-8,30,31 of enolate 10:414,415 of methylenecyclohexane 6:21,
22,53,54 ofpiperidone derivative 14:734 Rh (II)-mediated 10:407 Robinson annulation 6:17-21, 29,30 with 3-methylsilyl-3-butene-2one 10:414,415 Annulatophenonoside 30:624 Anochertus sedilloti 5:223-225,238,254 Anodic methoxylation 13:485,494 Anodic oxidation 7:161,163;8:159172;13:474,475,479 of c~-N-acetyl-~-N-tosy-L-lysine methyl ester 12:309,310 Anogeissinin 23:420 Anogeissus acuminata var. lanceolata 26:224 anolignan A & B from 26:224 Anogeissus latifolius 26:1157 Anogeissus sp. 26:1157 Anolignan A&B 26:224 HIV-1 RT inhibition by 26:224 Anolignan B 26:228,231 Anomalin 25:471,476 Anomalous metabolism 7:117 Anomalous ORD 2:160 Anomeric configurations 27:469,667 in aglycone 27:667 Anomeric deprotection 6:413-416 of disaccharide dipeptides 6:413-416 Anona spp. 28:392 Anonaine 21:84 (-)-Anonaine 24:857 hypotensive effect of 24:857 Anopheles 26:781,782 Anorexia 22:588;30:369 effect of circadian activity on 369 C15Ansa chain 23:54 C17Ansa chain 23:54 C23Ansa chain 23:54 CgAnsa chain 23:54 Ansa compounds 23:52 Ansachain 5:592 "Ansa-Chain" compounds 12:39 rifamycin S 12:37 rifamycin W 12:39 Ansamitocin 9:435;23:54 (P-3)-Ansamitocin 9:433,434
41 Ansamitocin P-0 23:71 P-3-Ansamitocins 23:71 P-4-Ansamitocins 23:71 Ansamycin 2:424,9:431-445,10:153; 23:51 ;24:545-546 antiviral microbial-derived compound 24:545-546 classification of 23:53,54 discovery of 23:53 Ansamycin antibiotics 23:51-106 antitumor activities of 23:96 biological properties of 23:93 cytotoxic activities of 23:96 Ansamycin lactams 10:149,150 Ansamycins 21:374,420,435,436,437; 23:79 biosynthesis of 23:79 Ansathiazin 23:54,61 Ansatrienin 23:54 Ansatrienin A 9:434 Ant repellant 6:142 neoxanthin as 6:142 Antagonism 21:601 ;26:240-245 of platelet activating factor (PAF) 26:240-245 6-Antagonist activity 30:810,811,817 against DEL antinociception 30:811 in vitro 30:818 of DTAOH 30:810,811 of DTOH 30:810,811 of 6-opioid receptor 30:818 Antagonist cannabinoid receptors 25:532 Antagonist effect 25:533;26:756 of dioxin 26:756 of oripainine 25:533 Antagonistic activity 20:515;21:233; 23:187;26:460,1065 Antagonistic alkaloids 21:4 Antagonists 21:52;22:16 ~c-Antagonists 30:807 Antedematose activities 21:633 Antemisin 25:349 Antharufin 25:543 Anthelmintic activity 1:408,5:552; 23:356;26:425,446,450,451,456,466, 476,478,481,482,487,491
ofpsoralen 23:356 Anthelmintic agents 12:3 Anthelmintics 26:426,431,444,465,478, 479,493;28:331,332 broad spectrum activity of 28:332 diminished activity of 28:331 Anthelvencins 5:552,553 Anthemidin 7:233 Anthemis nobilis 22:679 Anthemis saguramica 10:153,162 Antheraea polyphemus 22:387 (+)-Anthocerotonic acid 26:185 Anthocidaris crassispina 25:868 ganglioside GM5 from 18:486 Anthocyanidin 21:497;26:743,744,747, 748,770,771 Anthocyanidins 7:112,114,72322:421, 631-633;27:89328:275 cyanidin as 28:275 delphinidin as 28:275 malvidin as 28:275 pelargonidin as 28:275 structure of as 28:275 Anthocyanin pigments 23:773 Anthocyanins 5:646,647,658,7:192,723, 731,735;22:167,631,633;23:742; 25:513;26:305;28:275,276,277,292 cyanidin-3-glucoside as 28:275 delphinidin-3-glucoside as 28:275 for coronary heart disease 28:292 from black grapes 28:276 an blackberry 28:277 in blueberry 28:277 m cabbage, red 28:277 m cherry 28:277 in chokeberry 28:277 in cranberry 28:277 in currant (black) 28:277 m food plants 28:276 m grape (red) 28:277 m onion 28:277 in organe, blood (juice) 28:277 m raspberry, red 28:277 in strawberry 28:277 an wines, porto 28:277 in wines, red 28:277
42 malvidin-3-glucoside as 28:275 pelargonidin-3-glucoside as 28:275 Anthocyridin idB 25:616 Anthonomus grandis 1:693,7:187,190 Anthopleura elegantissima 2:306,9:493495 ;25:873 ;28:647 mycosporine-taurine from 28:647 Anthostoma avocetta 21:229 Anthoxanthum sp. 29:584 Anthozoa 23:153 Anthracenes 11:113,277 Anthracenone abscisic acid analog 27:331 Anthracnose fungi 9:228,230,240 Anthracophyllum archer 29:272 Anthracophyllum discolor 29:279 Anthracophyllum sp. 29:283 Anthracycline antibiotics 14:492; 21:157 antitumor activity of 14:492 Anthracycline prodrug 21:175 Anthracyclines 21:157,158,168 Anthracyclinone 4:318;21:162 biological activity of 4:318 cardiotoxicity of 4:318 Anthraflavic acid 25:543,544,541 Anthragallol 3-methylether 26:659 Anthragallol 26:657,659 2,3-dimethylether of 26:659 Anthramycin 23:256 Anthranilic acid 23:341 ;26:966,967, 969,970-972,1005,1008 Anthraquinone (alizarin) 26:629 Anthraquinone mitoxanthrone 14:21 Anthraquinone sulphonates 20:867 Anthraquinone-2,6-disulphonate 20:857 Anthraquinone-based PKA inhibitors 25:544 Anthraquinones 3:433,434;7:418-420, 427; 13:662,663 ;20:277 ;21:203,212; 22:557,572,575,597,617;25:509,513, 541 ;27:849;30:304,307 alizarin 25:541 anthrarufin 25:541 chrysazine 25:541 chrysophanic acid 25:541 emodin 25:541
from leguminoseae 30:304 from rubiaceae 30:304 purpurin 25:541 quinalizarin 25:541 quinizarin 25:541 structure-activity relationship (SAR) of 30:307 Anthraserpine 9:174 Anthricus sylvestris 18:555;26:215 anthricin from 18:555 deoxypodophyllotoxin from 26:215 (-)-deoxypodorhizone from 26:215 (-)-hinokinin from 26:215 nemerosin from 26:215 morelensin from 26:215 Anthrobacter citreus 20:234 Anthrobacter sialophilus 27:115 Anthrobacter simplex 20:234 Anthrobacter ureafaciens 16:87 Anthrotaxis spp. 3:456 Anti TNF-c~ antibody 25:461 Anti-addictive activity 21:95 Antiadrenergic alkaloids 21:102 Anti-AIDS activity 23:705 ofbetulinic acid 23:705 Anti-AIDS agent 11:267 (+)-castanospermine 11:267 Antiallergenic drug 26:759 Antiallergenic effects 12:398;26:264, 265 of K-252a 12:398 of staurosporine 12:398 Anti-allergic 30:71,72 baicalein as 30:71,72 Antiallergic activities 18:674;21:656, 657,659,594 ;23:364 ;26:759 of coumarin 23:335,356,357, 353,368,376,393,550,553 Antiallergic drugs 29:300 synthesis of 29:300 Antiallergic properties 21:660 Anti-angiogenesis 24:875 as biological action 24:875 Anti-angiogenesis action 24:875-925 of Kampo medicines 24:875-926 Antiangiogenic activity 21:437 Antiangiogenic agents 26:757
43 Antiangiogenic effects 30:63 ofganoderic acid F 30:63 Antianoxic activity 21:585 Anti-anxiety agent 26:413 Anti-apoptotic effects 28:175 Anti-arabic antibodies 29:543 Antiaris toxicaria 28:203,220 antiarone A from 28:203 antiarone B from 28:203 antiarone E from 28:204 antiarone J from 28:203 antiarone K from 28:203 ficusins A from 28:204 uses for arrow poison 28:203 Antiarone B 28:229 biological activity of 28:229 Antiarone F 28:229 biological activity of 28:229 Antiarone G 28:229 biological activity of 28:229 Antiarone H 28:229 biological activity of 28:229 Antiarone I 28:226,229 anti-human immunodeficiency virus (HIV) activity of 28:226 biological activity of 28:229 Antiarone J 28:229 biological activity of 28:229 Antiarrhythmic activity 23:356;30:200 of coumarin 23:335,356,357, 353,368,376,393,550,553 of loreainide 30:200 Anti-ARS2 antibody 25:435 Anti-arthritic agents 22:116 Anti-asthmatic activity 24:852 Antiatherosclerotic activity 23:355,468; 28:257,293 of organosulfar compounds 23:355,455-485 ofpolyphenols 28:257,293 Anti-bacterial 24:25 biological activity of 24:25 Antibacterial activities 5:512,747;10:78, 117;11:134;12:398;14:145;20:245, 712;21:21,108,109,190,207,213,214, 230,237,262,266,267,275,284,601, 615 ;23:41,126,164,235,258,355,468, 375,472,473,531,534,800;24:573,
856,857 ;26:226,1002;28:140,688; 30:328,738 of 1,2,3-trithiane 23:235 of 3',4'-dideoxykanamycin 14:145 of 5-methoxydehydrodiisoeugenol 26:226 of acteoside 5:512 of allicin 23:473 of allicin 23:473 of anonaine 24:856,857 ofbenz [a] anthracene antibiotics 11:134 of bicyclic phloeodictine B 28:688 of caryophyllene 23:535 of celastrol 5:747 ofcopalliferol A 23:534 ofcopalliferol B 23:534 of coumarin 23:335,353,356, 357,368,376,393,550,553 of curcmene derivatives 23:164 of curcumene derivatives 23:164 ofcurcumenes 23:180 ofcurcumenes 23:180 of dicoumarol 23:354,375 of dicoumarol 23:375 of dihydrodiisoeugenol 26:226 of distichol 23:535 of forsythiaside 5:512 of HA 26:1002 of Hypericum perforatum 30:628 of ikarugamycin 28:140 of ircenals 24:573 of isoeugenol 26:227 of kaempferol 23:535 of myricetin 23:535 of organosulfar compounds 23:355,455-485 of organosulfur compounds 23:355,468 ofphenylpropanoids 5:512 of resorcinols 30:158 ofresveratrol 23:531 ofresveratrol 23:74,531,534,746 of rhein 30:328 of saframycins 10:78 of SAM 23:41 of SAM MM1 23:41"
44 of sampangine metabolites 23:40 of sennosides 30:328 of sesquiterpenes 23:180 of sesquiterpenes 23:180 of staurosporine 12:398 of streptomycin 23:41 of streptormycin 23:41 of suspensaside 5:512 of teraxasterol 23:535 of tetrazomine 10:117 of thiosulfinates 23:472 of thiosulfinates 23:472 of toralactone 30:328 of trithiane 23:235 of urochordamine A 23:258 of urochordamine B 23:258 of (x-gurjunene 23:535 of ~-hydroxyacteoside 5:512 Antibacterial agent 5:377 aplasmomycin as 5:377 aurantinins as 5:601 chimeramycin as 5:613 Antibacterial effect 23:135 of [3-glucans 23:107,111,115,135 Antibacterial flavone 30:740 structure of 30:740 Antibacterial macrolide 5:613,747 Antibacterial metabolite 23:165 Antibacterial properties 30:628 against Staphylococcus aureus 30:628 Antibacteriophage activity 21:408 Antibiotic 24:799 biological activity of 24:799 Antibiotic activity 11:130;12:192; 17:283 ;21:188,202,223,239,364,437; 23:649;24:953-954;28:121 of 2-isocephems 12:192 of 2-iso-oxacephems 12:192 of celastroloids 23:649 of equisetin 28:121 of HIRE 24:951-954 ofmacrolide 17:283 of semivioxanthin 11:130 of thienamycin 12:188 Antibiotic potency 4:432 of imipenem 4:432
of 1-[3-methylthienamycin analogue 4:432 Antibiotic T-1384 5:549 Antibiotics 30:738 ansamycin 9:431-445 bio-organic chemistry of 9:431-445 biosynthesis of 11:207-213 from microorganisms 5:589 isoquinolinequinones 10: 77-145 mitomycin 9:431-445 relative configuration of 6:261 shikimic acid derived 11:182-191 sugar components of 11:213-222 Antibiotics A 26771 B 11:194 by Penicillium turbatum 11:194 Anti-bleeding activity 26:56 of Dianthus superbus var. longicalycinus 26:56 Antibodies 2:345-348;7:29;29:521, 529-532 active sites of 29:529 activity of 29:531 against carbohydrate containing antigens 29:521,536 against Streptomyces pyogenes 29:537 anti-BSA 29:532 anti-gum arabic 29:532 anti-lactose 29:532 antigen complex of 29:531 as vaccines 29:521 immunoglobulin classes of 29:521 in medicine 29:521 inhibition of 29:521,531 inhibition patterns of 29:536 inhibition via agar diffusion data 29:531 role in immunization 29:524 secretion of 29:525 Antibody dependent cell mediated cytotoxicity (ADCC) 25:273 Antibody dependent cellular cytotoxicity (ADCC) 27:803 Antibody directed enzyme prodrug therapy 21:157 natural anthracyclines for 21:157
45 Anti-CAM IgG 25:491,492 Anticancer activity 14:805;21:135,136; 23:335,356,357,353,368,376,393, 550,553;26:741,760,1060;27:807 Anticancer agent 14:805;19:511; 22:234;30:291 Scutellaria indica use as 30:291 Anticancer compounds 13:347-382; 14:805 Anti-cancer effects 23:475 ofallyl sufides 23:475 Anticancer peptide 27:799 Arg-D-Trp-NmetPhe-D-Trp-MetNH2 as 27:799 Anticancer treatment 14:805;26:162, 163 Anticandidal activity 20:485 Anti-carcinogenic activity 21:585; 22:345 ;28:257,293 ofpolyphenols 28:257,293 Anticaries activity 18:673 Anti-catarrhal activity 26:398 Anti-ChE activity 21:748 Anticholinergic 21:102 Anticholinergic agents 17:395 Anticholinesterase activity 22:30 Anticholinesterase alkaloid 21:744 Antichromonal action 22:625 Anti-CMV activity 30:404,405 ofSargassum horneri 30:405 of seaweeds 30:404 of sulphated polysaccharide (PS) 30:405 Anticoagulant activity 30:395,399,403 of coumarin 23:335,353,356, 357,3 68,376,393,550,553 ofheparin derivatives 30:399 ofpolysaccharide (PS) 30:395 of sulphated polysaccharides (PS) 30:403 Anticoagulation 30:838 mechanism of 30:838 Anti-coagulative principles 23:835 Anticoccidial activity 21:401 Anticoccidium agent 4:591 Anti-complement activity 22:136; 25:46;26:340 of serotonin agonists 25:46 of cyclic AMP-dependent protein
kinase 25:46 ofserotonin agonists 25:46 Anti-complementary 22:307 Anti-complementary activity of OG 25:17 Anticonvulsant 22:511,524,534 Afraegle paniculata as 22:511 Arisaema amurense var. serratum as 22:512 Asparagus recemosus as 22:513 Jatropha gossypifolia L. as 22:524 Jatropha multifida L. as 22:524 Lantana camara L. as 22:524 Tetrapleura tetraptera as 22:534 Anti-convulsant activity 24:858;28:176 of bilobalide 28:176 Anticonvulsant agent 22:511,512, 515-517,519,524,532,534 ;26:413 Afraegle paniculata as 22:511 Ampelopsisjaponica as 22:511 Boerhavia diffusa L. as 22:514 Clausena anisata as 22:517 Calliandra portoricensis as 22:515 Cinnamomum camphora as 22:516 Carum carvi L. as 22:515 Arisaema amurense var. serratum as 22:512 Calliandra portoricensis as 22:515 Carum carvi L. as 22:515 Cinnamomum camphora as 22:516 Clausena anista as 22:517 Daucus carota w. as 22:517 Jatropha gossypifolia L. as 22:524 Jatropha multifida L. as 22:524 Lantana camara L. as 22:524 Solanum dasyphyllum as 22:532 Solanum nigrum as 22:532 Tetrapleura tetraptera as 22:534 Anticonvulsive action 26:399 Anticonvulsive agent 22:512 Ampelopsisjaponica as 22:512 Anti-crocin mAb 25:957
46
Antidepressant 30:603,624,627 activity of hyperforin 30:627 activity of Hypericum perforatum as 30:624 use of hypericin as 30:624 use of Hypericum perforatum 30:627 Antidepressant drugs 21:101 Anti-depressant effects 28:177 of Ginkgo biloba L. 28:177 Antidepressant efficacy 30:335,626,627 chemical modification of 30:627 of Hyperici herb 30:335 of hypericin 30:626 Antidepressant-like effect 30:204,334 in forced swimming test 30:334 in mice 30:204 of Hyperici herb 30:334 of Siphocampylus verticillatus extract 30:204 Antidesmin A 406 Anti-dextran antibodies 29:538 of the IgG class 29:538 Anti-diabetic agents 7:47;30:340 quinonic derivatives as 30:340 Amidiarrheal activity 30:200 of loperamide 30:200 Anti-digoxin antibodies 15:374 Antidote 5:751 for scorpion sting 5:751 for snake bite 5:751 Antidote activity 22:460,462-482 Antidysenteric agent 5:758 Antiedema activity 12:384;22:443 of staurosporine 12:384 Antiemetic agent 24:900 gingerol as 24:900 Antiepileptic 22:516 Celastrus paniculta as 22:516 Withania somnifera L. as 22:535 Antiepileptic activity 22:516,517,532, 535 of Celastrus paniculata as 22:516 of Citrullus colocynthis as 22:517 of Solanum sodomaeum L. as 22:532
of Withania somnifera L. as 22:335 Antiepileptic agent 22:517,532 Citrullus colocynthis as 22:517 Solanum sodomaeum L. as 22:532 Antiepileptic drugs (AED) 22:507 Antiestrogenic activity 26:221 Antiestrogenic effects 26:209 Anti-exudative activity 22:97 Anti-fatty liver 30:94 action of Platycodi radix 30:94 Antifeedant 17:153,234,23724:845,866 bioassay of 24:866 biological activity 24:845 Antifeedant activity 2:277;10:425; 21:254,273,611,770;23:319,321, 341-344,348,666,670,671 ;24:101; 26:461,851 ;28:480;30:696 against insects 23:666 against mammals 28:480 of (-)-specionin 10:425 of 1-deoxy-2 [3,3[3-epoxynagilactone A 28:480 of allicin 23:341 ofamphotericin B 23:343 ofbombinins 23:341 ofbruceantin 23:321 of Celastrus angulatus 23:666 of chlorodimeform 23:319 of chlorodimeform 23:319 of cispentacin 23:344 of culmorin 23:344 of drosomysin 23:341 of griseofulvin 23:343 ofjaspamide 23:341 ofjuglone 23:342 ofleukotoxin 23:341,345 of majusculamide 23:344 ofnagilactone A 28:480 ofnagilactone C 28:480 of neoquassin 23:319 of nigakilactone E 23:319 ofPachyrrhizus erosus 24:779, 822-826 ofperoxyplakoric acid 23:341 ofpicrasin B 23:319,321 ofpradimicin A 23:343 of pristimerin 30:696
47 of quassin 23:319,321 of sesquiterpenes 23:670,671 of sinharine 23:343,348 of tannic acid 23:341 of tingenone 30:696 of tomatin 23:342 of xanthylletin 23:342 ofyadanziolide A 23:321 ofyurendide 23:341 Antifeedant assays 18:771-774 Antifeedant effect 26:853,861,863,871, 874,876 Antifeedant properties 22:234 Antifeedant sequiterpenes 23:668,669 from Elaeodendron buchananii 23:669 from Euonymusfortunei 23:668 from Euonymus bungeanus 23:668 of SAM 23:41 Antifeedants 7:395-397;29:129 polygodial as 29:129 warburganal as 29:129 Anti-fertility action 2:229-231 ofplumbagin 2:229-231 of Plumbago zeylanica 2:229, 231 ofisoshinanolone 2:229-231 Anti-fertility activity 5:754 antifertility activity of 21:759 antifungal activity of 21:758 ofpseudolaric acid B 21:759 Antifouling 17:93,98 Anti-fouling assay 21:36 Anti-fungal 24:25,799 biological activity of 24:25,799 Antifungal activities 21:186,192,197, 203,206,213,214,218,221,226,227, 233-235,223,238,240,389,391,399, 404,405,435,599-662 ;22:626;23:3,4, 271,341,344,348,468,473,798,801, 354,368 ;26:227,228,553,1098 ;28:4; 66,473,475,686;30:327,738,629 against Candida albicans 30:327,629 from Hypericum roeperanum 30:629 of (E)-8(17), 12-1abdadiene15,16-dial 23:798
of (E)-8b, 17-epoxylabd- 12-ene15,16-deol 23:798 of (E)-813,17-epoxylabol- 12-ene15,16-dial 23:798 of 2-hydroxynagilactone F 28:475 of 2-thioxopyrrolidines 26:1098 of 3,4,3 ',4'-tetramethoxylignan7-ol 26:228 of 3,5'-diallyl-2'-hydroxy-4methoxybiphenyl 24:861 of 3,5-Diiodetyramine 23:235 of 3-methoxysampangine 23:4 of 3-methylsampangine 23:9 of 4'-O-demethldehdropodophyllotoxin 26:227 of alga 5:342 of allicin 23:341,473 ofambigol A 23:342 ofamphotericin B 23:343 of aumulone 23:342 of Batzella sponge 28:685 of biphenyl ether,4,4'-diallyl-2,3'dihydroxybiphenyl ether 24:861 ofbombinins 23:341 ofbroussoflavonol G 28:4 ofbroussonin A 28:16 ofbroussonin B 28:16 of canaliculatol 23:534 of cardigone 23:342 of cispentacin 23:344 of coelenterate 5:342,368 of cordigol 7:408 of cordigone 7:408 of coumarin 23:335,356,357, 353,368,376,393,550,553 of culmorin 23:344 of discobahamin A 23:341 of drosomysin 23:341 of flavolol 3-methyl ether 7:414 of flavonoids 7:413 of garcigerrin 7:423 of glutionosone 23:343 of griseofulvin 23:343 of humulone 23:342 of hydroquinone uncinatone 7:408 ofintrapetacin A 28:66
48 of intrapetacin B 28:66 ofjaspamide 23:341 ofjuglone 23:342 of labdadiene- 15,16-dial 23:799 ofleukotoxin 23:341 of LL-Z1271c~ 28:473 of magnolol 24:861 of majusculamide 23:344 of mollusk 5:342 ofmyristic acid 23:348 ofnagilactone C 28:475 ofnagilactone E 28:475 of nanaomycins 11:127 of napthoxirenes 7:423;23:342 ofoidiodendrolide B 28:475 ofoidiolactone D 28:475 of ooponol 23:354 of organosulfar compounds 23:355,468 ofpapsorbic acid 23:342 o f Penstemon roseus 24:838 of peroxyplakoric acid 23:341 of polyoxins 23:343 ofpradimicin A 23:343 ofpseudolaric acid B 21:758 of pterocarpans 7:414 of pyrrolnitrin 23:344 of rhizocticin A 23:344 of SAM 23:41 of SAM MM1 23:41 of sampangine metabolites 23:3, 40 of sampangines 23:3,9,341 of semivioxanthin 11:130 of sesquiterpenes 2:287 of sinharine 23:343 of sponge 5:342,368 of streptomycin 23:41 of tannic acid 23:342 of thujaplicins 23:343 of tomtin 23:342 of tunicate 5:342 of urdamycin 11:134 of vaticaffinol 23:534 of vitamin A 23:271 of vitamin B 23:271 of vitamin B 23:271 of xanthones 7:410;30:629
of xanthyletin 23:341 of yurenolide 23:341 Antifungal activity evaluation 23:41 of SAM 23:41 of SAMMI 23:41 of SAMM2 23:41 of SAM MM1 23:41 of streptomycine 23:41 Antifungal agents 4:513;17:239;26:368; 24:406 Antifungal antibiotic 5:597,607,613; 21:388 cerulenin as 5:613 irumamycin as 5:597 phhoamycin as 5:607 Antifungal compounds 7:406,408,415; 23:13 Antifungal drug 23:3 sampangine as 23:3 Anti-fungal effects 23:481 of allyl sufides 23:481 Antifungal flavones 7:413 Anti-fungal green house 24:864 bioassay of 24:864 Anti-fungal holothurin 28:597 from Psolus patagonicus 28:597 Antifungal metabolites 21:187,190 from biological control fungi 21:187 Antifungal property 23:335-393 of coumarin 23:335,356,357,353 368,376,393,550,553 ;27:381 Antifungal pseudolaric acid B 21:754 Antifungal pyridone 21:213 Antigen 24:939 Antigen activation 30:592 induced by TPA 30:592 in Raji cells 30:592 Antigen modifications 29:533 by borohydride methods 29:533 by carbodiimide methods 29:533 by isoelectric focusing 29:533 by lipid isoelectric focusing 29:534 by monosaccharide oxidation 29:533 O-Antigen 6:262 from Salmonella anatum 6:262 synthesis of 6:262
49 Antigen preparation 29:528 from CNBr activated sepharose 29:528 of glycoconjugates 29:528 of glycoproteins 29:528 of immunoadsorbents 29:528 of microbes cell walls 29:528 Antigen-antibody reaction 21:659 Antigenic activity 26:1126 I-Antigenic determinant 10:483 O-Antigenic polysaccharide 14:236 from Pseudomonas aeruginosa 14:236 from Salmonella newington 14:233 from Shigella flexnert 14:233 Antigenic specificity 4:197 Antigenotoxic agent 26:271 I Antigens 10:457-461 II Antigens 10:457,461 Anti-glycemic effects 24:902-904 ofhumulones 24:902-904 Antiglycosuric activity 26:398 Anti-HeLa cell growth 21:695 Anti-Helicobacter pylori activities 28:234,241,243 of 6,8-diprenylorobol 28:243 of dihydrolicoisoflavone A 28:243 of formononetin 28:241 ofgancaonin I 28:243 ofgancaonol B 28:243 ofgancaonol C 28:243 ofglabrene 28:241 ofglabridin 28:241 ofglyasperin D 28:243 of glycyrin 28:243 of glycyrol 28:241 of glycyrrhetic acid 28:241 of glycyrrhizic acid 28:241 of isoglycyrol 28:241 of isolicoflavonol 28:243 of licochalcone A 28:241 oflicochalcone B 28:241 of licoisoflavone B 28:241 of licorice flavonoids 28:234 of licorice-saponin 28:241 of licoricidin 28:241 of licoricone 28:243
of liquiritigenin 28:241 of liquiritin 28:241 of 1-methoxyphaseollidin 28:243 of 3-O-methylglycyrol 28:243 of vestitol 28:243 Anti-hepatitis activity 21:662 Anti-hepatitis B agents 20:527 Antihepatitis sarmentosin 21:737 Antihepatotoxic 30.749 effects of apigenin 30:749 effects ofluteolin 30:749 effects of nepetin 30:749 effects ofquercetin 30:749 Antihepatotoxic activities 17:377; 21:651 ;26:256;27:660 Antihepatotoxic agents 26:255 3-deoxysilychristin 26:255 silandrin as 26:255 silchristin as 26:255 silybin as 26:255 silydianin as 26:255 silymonin as 26:255 Antihepatotoxic effect 23:479;25:99 ofallyl sufides 23:479 of OGs from Abri Herba 25:99 of OG 25:98,99 Antiherpes activity 5:565 Antiherpetic activity 21:718 Antiherpetic drug 30:400 acyclovir 30:400 complications of 30:400 Antihistaminic activity 30:200 of astemizole 30:200 Antihistaminic dispacamide C 25:870 Antihistaminic dispacamide D 25:870 Antihistaminic drugs 26:262 Anti-HIV activity 19:511,748;21:132, 133,149,252,269,664,665 ;23:316, 533,534,687,704 ;24:742,743 ;30:226, 396,397,399 activity of 30:399 of bergenin 23:535 of dibalanocarpol 23:535 ofMerremia peltata 30:397 of natural quassinoid glycosides 23:316,318 of balanocarpol 23:533,534 of neotripterifordin 23:687 oforthosphenic acid 23:704
50 of polyphenols 30:226 of potassium salt ofcaffeic acid tetramer 24:742,743 ofsalaspermic acid 23:704 of sodium salt of caffeic acid tetramer 24:742,743 of tripterifordin 23:687 Anti-HIV agents 24:742;30:227,397 aryltetralins 24:742 mechanism of action of 30:397 polyphenols as 227 Anti-HIV cytopathicity activity 30:399 of marine invertebrates 30:399 Anti-HIV flavonoids 28:226 2-arylbenzofuran as 28:226 from Glycyrrhiza species 28:226 from moraceous plants 28:226 AntiHIV licochalcone 21:740 Anti-HIV polysaccharide (PS) 30:399 from marine alga 30:399 Anti-HIV sulphated polysaccharide (PS) 30:399,400 from Ganoderma lucidum 30:400 from Lentimus edodes 30:400 natural sources of 30:399 Anti-HIV therapeutic agents 30:399 Anti-HIV triterpenes 21:664 Anti-HIV-assay 20:535,536 Anti-HIV-screening 13:665 Antihormones 20:515 Anti-HRP monoclonal antibodies 25:334 Anti-HSV activity 30:403 of fucan sulphates 30:403 of Leathesia difformis 30:403 ofSargassum horneri 30:403 Anti-HSV agents 30:401 Anti-HSV sulphated polysaccharide (PS) 30:403 from Ganoderma lucidum 30:403 Anti-HSV-1 activities 21:665,695,718 Anti-HSV-1 bioassay 21:698 Anti-human immunodeficiency virus (anti-HIV) 28:631 activity of Didemnum sp. 28:631,634
Anti-human immunodeficiency virus (HIV) activity 28:225,226 ofantiarone I 28:226 ofbroussoflavonol B 28:226 ofbroussoflavonol C 28:226 ofgancaonin R 28:226 ofglyasperin A 28:226 of glycyrol 28:226 ofkazinol B 28:226 of kumatakenin 28:226 ofkuwanon H 28:225 oflicochalcone B 28:226 ofmoracin C 28:226 of morusin 28:225 of mulberry tree 28:225 of norartocarpetin 28:226 of prenylflavones 28:225 of wighteone 28:226 Antihyaluronic activity 26:556 Anti-hyperanalgesic activity 30:201 of SDZ-249-665 30:201 Anti-hyperglycemic 24:875 as biological action 24:875 Anti-hyperglycemic action 24:875-925 of Kampo medicines 24:875-926 Antihyperglycemic activity 18:672; 19:351 Anti-hyperglycemic effect 24:902-904, 917-922 chemical structure of 24:916 of humulones 24:902-904 of isohumulones 24:902-904 of Morus spp. 24:917 of N-containing sugar 24:916-920 of timosaponin 24:919-922 Anti-hyperglycemic medicinal plants 24:916-920 Antihyperlipidaemic action 30:94,107 of chondroitin sulfate 30:107 of Platycodi radix 30:94 Anti-hypertensive activities 21:501 of Forsythia suspensa 5:513 of K-252a 12:398 of staurosporine 12:384 of suspensaside 5:513 Antihypertensive effects 26:235,236 Antihypoxic activity 18:373
51 Antihysteric 22:526 Muntingia calabura L. as 22:526 Antihysteric agent 22:526 Muntingia calabura L. as 22:526 Anti-i-antibody 10:480 Anti-IFN-?' 25:464 Anti-IL-1 antibody 25:464 Anti-IL-6 antibody 25:464 Antiinfective drugs 23:111 Antiinfective effect 23:135 of [3-glucans 23:107,111,115,135 Anti-infective plants 30:396 in traditional medicine 30:396 Anti-inflammation 24:875 as biological action 24:875 Anti-inflammation action 24:875-925; 30:72 of baicalein 30:72 of Kampo medicines 24:875-926 Anti-inflammatory 24:799,852,869 bioassay of 24:869 biological activity 24:25,799,845 effect ofshin-I 24:852 Anti-inflammatory activities 5:367; 13:647;17:137,376;18:775 ;21:130, 134,153,152,312,591,594,690,616, 656,657;22:93,119,307,345,361; 23:158,297,512,602,832;25:43; 26:340,341,343,391,398,400,401, 403,404,406,415,418,482,556,558, 741,759,1035;27:660,858;28:200, 257,293 ;671,844;30:206,207,224, 225,292,320,689,743 Copaifera riticulata for 22:360 cytotoxic activity 23:180 Heisteria pallida for 22:360 of 2-substituted 3-chloro- 1,4naphthoquinones 30:320 of 3',4-O-dimethylcedrusin 22:361 ofbroussoflavonol G 28:4 of californian sponge 28:671 of cembrones 23:180 of coumarin 23:335,356,357, 353,368,376,393,550,553 ofCurcuma comosa 26:884 of curcumenoids 23:835 of curcuminoids 23:835 ofDrymis winteri as 30:206
of genus Morus 28:200 of kallilolides 23:180 ofMorus nigra 30.'207 of phenolic triterpenes 30:689 ofpolyphenols 28:257,293; 30:224,225 ofProtium kleinii 30:206 of pseudopterolides 23:180 ofpseudopterosins 23:158,180 of saikosaponins 23:512 of Salvia desoleana 26:416 of samaderines 23:297 of Saponaria officinalis 26:27 of secopseudopterosins 23:180 of secosterols 23:168,180 of Sideritis javalambrensis 30:292 of Sideritis mugronensis 30:292 of sterols 25:43 of Tripterygium wilfordii 30:689 of triterpenes 30:689 of triterpenoids 25:43 Anti-inflammatory agent 5:753;7:397, 14:315 ;21:616;24:898;26:32 aconitine as 24:898 barbatoside A as 26:56 barbatoside B as 26:56 from Dianthus barbatus 26:32,56 Anti-inflammatory diterpenoids 23:688 Antiinflammatory drug 17:130;23:111 Anti-inflammatory effect 26:262,263, 264;30:206 of feverfew 30:206 of K-252a 12:398 of parthenolide 30:206 of staurosporine 12:398 Anti-inflammatory inhibitor 23:175 Anti-inflammatory reactions 30:72 Anti-influenza activity 30:407,408 of Cochlodinium polykrikoides 30:408 of Crenomytilus grayanus 30:408 of Nothogeniafastigiata 30:408 of Pinus parviflora 30:407 ofSpirulina platensis 30:408 of Ulva lactuca 30:408 Antijuvenile hormones 22:395
52
Anti-lactose antibodies 29:538 Antileishmanial activity 21:674,744; 26:229,790,813,887,789,790,791, 800,805,807,810,811,821,828,830; 30:742 of Baccharis dracunculifolia 30:742 of Baccharis genistelloides 30:742 ofBaccharis incarum 30:742 of Baccharis pentlandii D.C. 742 ofBaccharis salicifolia 30:742 ofBaccharis tricuneata 30:742 of genus Baccharis 30:742 of lignans 26:229,790,813,887 in vitro 30.'742 Antileukemic activity 1:305;4:232; 7:382-387,390;17:348;23:70,285, 490,649;24:573 of ansamitocin P-3 23:71 of asperdiol 23:490 of bisbrusatolylglutarate 23:305 of bisbrusatolylmalonate 23:304 ofbruceanol A 23:313,288 ofbruceanol B 23:313,288 ofbrusatol 23:304 ofbrusatolyl esters 23:304 of diterpene triepoxides 23:649 of gnidimacrin 23:490 of ircenals 24:573 ofjatrophone 23:400,490 of natural maytansinoids 23:70 of semisynthetic maytansinoids 23:70 Antileukemic P388 activities 21:770 Amileukemic principle 23:70 Antileukoderma 23:356 methoxsalen 23:356 Antileukoderma activity 23:356 of methoxsalen 23:356 Antilipoperoxidant 22:307;30:223 Anti-malarial activity 7:391-393,424; 21:346;23:301,838;24:282;26:779, 1036 of 3-geranyloxy-6-methyl- 1,8dihydroxyanthrone 7:424 o f 3-geranyloxy- 6-methyl- 1,8dihydroxy anthraquinone 7:424 of acetylvismione D 7:424
of amarolide 23:301 of artemisinin 7:424 of chaparrin 23:301 of chaparrinone 23:301 of chloroquine 23:301 of Cinchona succiruba 26:779 of glaucarubolone 23:301 of holacanthone 23:301 of quassinoids 7:391-394; 23:285-333 of quinine 7:424 ofvismione D 7:20 Anti-malarial agents 8:391-394,351; 20:516-521 ;30:330 against chloroquine-sensitive (T9-96) 30:330 Antimalarial assay 30:596 in vivo 30.596 of alkaloids 30:596 Antimalarial compounds 22:145 Antimalarial drugs 25:327,360;26:1035; 30:595 as chemosensitizers 30:595 as resistance-modifiers 30:595 chloroquine sensitivity in 30:595 Antimalarial effects 30:561,588,595, 597 of Hernandia moerenhoutiana 30:561 of Hernandia voyronii 30.561, 577 ofHernandia sp. 30:588 ofhervelines A-D 30:595 of laudanosine 30:595 of reticuline 30:595 Antimalarial naphthoquinones 30:330 atovaquone 30:330 Antimalarial therapies 25:361 Anti-metastatic activity 28:559;30:56, 58,59,60,64,69,152,292,329,628,629, 738 against Bacillus subtilus 30:293 against gram-positive bacteria 30:629 against Klebsiella pneumonia 30:293 against Staphylococcus aureus 30:293,329 against Staphylococcus
53
epidermidis 30:293 chemical instability 30:628 from Ganoderma lucidum 30:58 from Hypericum perforatum 30:628 from Hypericum japonicum 30:629 from medicinal plants 30:738 from novoimanine 30:628 in mice 30:59 of carp oil 30:56,64,69 of flavonoid 30:292 of Ganoderma lucidum 30:60 of Ginkgo biloba 30:152 of hyperforin 30:628 of natural products 28:559 of triterpenoids 30:58 of phloroglucinol derivatives 30:629 uses in folk medicine 30:738 Antimetastatic agents 19:351 Antimetastatic effect 16:93;25:441 on CVS 25:441 Antimetastic immunity 25:429 Anti-microbial 24:863-864 biological activity 24:799 bioassay of 24:863-864 Anti-microbial action 24:112 Anti-microbial activity 5:752;10:443; 15:327-339;18:776-778;21:153, 235,257,401,571,573,591,596,597, 599,606;22:626;23:94,153,180,233, 237,249,262,268,267,346,353,522; 24:64,69,206,330,331-334,402,403, 404,406,417,418,443,470,485,859, 1091,1092,1189;26:64,330,401,402, 1189;27:807;28:62,224,257,293,698, 671 against Candida albicans 5:752 against Clostridium difficile 5:601 against Clostridium perfringens 5:601 against gram-positive bacteria 23:94 against Proteus mirabilis 5:752 against Proteus vulgar& 5:752 against Staphylococcus aureus 5:752
of (-)-acetomycin 10:443 of 13-methylpentadecanoic acid 26:64 of phenylethanoids 26:330 of 3-O-methylglycyrol 28:224 of 3 [3-O-cis-p-coumaroyl alphitolic acid 28:62 of 3[3-O-cis-p-coumaroyl maslinic acid 28:62 of 3 [3-O-trans-p-coumaroyl alphitolic acid 28:62 of 3 [3-O-trans-p-coumaroyl maslinic acid 28:62 ofalphitolic acid 28:62 of AMOX 28:224 of amphibian venoms 15:327-339 ofbetulinic acid 28:62 of californian sponge 28:671 of coumarin 23:335,356,357, 353,368,376,393,550,553 of cryptolepine 5:752 of cyclocolorenone 24:859 of defensins 23:346 of dimer triterpenes 18:776-778 of dithiocarbonates 26:1091, 1092 of essential oil 21:571,596 ofeudistomin U 23:267 of eudistomins 23:233,262,268 of formononetin 28:224 of Fraxinus ornus 26:334 ofgancaonin I 28:224 ofgancaonol B 28:224 of glabrene 28:224 of glabridin 28:224 ofglyasperin D 28:224 of glycyrin 28:224 of glycyrol 28:224 ofhalistanol sulfate 28:698 of HMPT 26:1091,1092 of hydroxycoumarins 26:330 of isoglycyrol 28:224 of isolicoflavonol 28:224 of lamellarins 23:249 of Licania heteromorpha vat. heteromorpha 28:62 oflicochalcone A 28:224
54 of licochalcone B 28:224 of licoisoflavone B 28:224 of licorice flavonoids 28:224 of licoricidine 28:224 of licoricone 28:224 of liquiritigenin 28:224 of liquiritin 28:224 of medrrhodine A and B 5:618 of MMTP 26:1091,1092 of MTBI 26:1091,1092 ofpolyphenols 28:257,293 ofpseudopterosins 23:153,158 of Salvia officinalis 26:402 of Salvia sclarea oil 26:401 of secoiridoids 26:330 of secopseudopterosins 23:180 of sesquiterpenes 2:287,288 of theonellapeptolides 26:1189 of triterpenes 18:776-778 of tyramine 23:237 of verbascoside 23:522 of vesititol 28:224 Antimicrobial agent 5:753 Antimicrobial alkaloids 21:109 Antimicrobial consitituents 21:607 Antimicrobial peptide 22:83 Antimicrobial properties 27:378 Antimicrosporidial activity 26:458 Anti-migrane principle 24:849 in Tanacetum parthenium 24:849 Antimitotic activity 5:461 ;23:359,376; 30:224 of coumarin 23:335,356,357, 353,368,376,393,550,553 of gigantecin 9:396 of lignans 5:461 ofpolyphenols 30:224 Antimitotic agent 22:482;30:5 discodermolide as 30:5 Antimitotic inhibitory activity 24:406 of combretastatin A-4 24:406 Anti-mu stimulation 25:272 Anti-mutagen 24:851 Antimutagenic 21:641 Antimutagenic activity 21:583,584,585, 616,641,642 ;23:107 ;26:1099,1100; 30:315-317,765
of [3-glucans 23:107 of chlorophyllin 30:765 of quinones 30:315-317 Antimutagenic agent 22:307 Anti-mutagenic effects 23:478;26:510 ofallyl sufides 23:478 Antimycine A 16:694 antifungal agent 16:694 Antimycobacterial activity 23:4,9 of 3-methylsampangine 23:9 of sampangines 23:9 Antimycoplasmal activity 11:127 ofnanaomycins 11:127 Antimycotic activity 22:70,81 ;23:4 Antimycotic/antimycobacterial activity evaluation of 23:4 3-methoxysampangine 23:4 Antinematodal activity 26:425,433, 456,457,464,472,483,484,488,494 Antinematodal agents 26:456 Antinematodal effect 26:481 Antineoplasic activity 21:389;28:470 against P 388 cells 28:470 Anti-neoplasmic activity 27:378,386 Anti-neoplastic activity 4:29;22:248, 558;24:309-318;30:732 of plants 30:732 Antineoplastic agent 28:145,648-49 dolastatin 3 as 28:648 dolastatin 10 as 28:145,649 Antineoplastic drugs 26:158,169,214, 799,825 Antineoplastic glycoproteins 7:285 Antinociception 30:204,802,805 in vivo 30:805 inhibition by opioid receptor antagonist 30:204 monoamine-synthesis inhibitor 30:204 Antinociception action 30:201,204,205, 206,207,800,804,814,815,816 by GABAergic receptor 30:204 by intracerebroventricular 30:814 by noradrenergic receptor 30:204 by serotonergic receptor 30:204 in capsaicin model of pain 30:205
55 in mice 30:814,816 in neonate rats 30:206 in rats 30:814 in vitro 30:804 in vivo 30:207 mechanism of 30:205 of (-)-menthol 30:207 of (+)-allomatrine 30:205 of (+)-matrine 30:205 of biflavonoids 30:207 of cannabinoids 30:194 of cis-8,10-di-N-propyllobelidiol hydrochloride dihydrate (DPHD) 30:204 of DEL 30:800 ofDEL C analogues 30:815 ofdeltorphin B 30:804 of DER 30:800 of dispsacus saponin C 30:204 of drimanial 30:206 of glycopeptides 30:816 of hodgkinsin 30:205 of kalopanaxsaponins-A 30:203 of kalopanaxsaponins-I 30:203 of morusin 30:207 of naltrindole 30:816 of piperidine alkaloid hydrochloride 30:204 ofprenylflavonoid 30:207 ofProtium kleinii 30:206 ofRheedia gardneriana 30:207 of SDZ-249-665 30:201 of Siphocampylus verticillatus extract 30:204 oftormentic acid 30:207 via glutamate NMDA receptors 30:205 Antinociceptive activity 21:591 Antinociceptive agent 30:205 incarvillateine as 30:205 Antinociceptive properties 30:206 ofDrymis winteri 30:206 Anti-obesity 30:79,88,94 action of 30:94 action of saponin 30:94 effects of 30:79 mechanism of 30:88 natural products as 30:79
Anti-obesity action 27:398,400,402,403 of chitosan 27:402,403 of natural products 27:398 ofodong tea 27:400 of soyasaponins 27:398 Anti-obesity activity 30:88 of Platycodi radix 30:88 Anti-obesity effector 30:80,82 from oolong tea 30:82 Anti-obesity effects 30:86,100 in high-fat diet-treated mice 30:86,101 inhibitory actions of 30:86 of chitin-chitosan 30:100 ofoolong tea 30:86 Anti-orientation 14:753 Antioxidant 4:495;9:371,372;21:618; 23:771 ;24:845,868 ;30:524,744 bioassay of 24:868 biological activity 24:845 garlic acid as 23:771 protective functions of 30:744 vitamin C (ascorbic acid) 30:524 vitamin E (tocopherol, TOH) as 30:524 Antioxidant activities 21:599,600,618; 22:308,321,345;23:395,534,535,742, 772,773,845 ;25:59;26:250,255,509,5 56,672,763,768,887,1005,1006;28:4, 16,17,63,179,257,293,773 ;30:173, 224,225,289,320,321,524,561,743, 745 of c~-tocopherol 26:1006 of 3-hydroxycoumarins 30:225 of 8-hydroxy-naringenin 28:64 of alizarin 26:672 ofanthocyanin pigments 23:773 of anthraquinones 30:320 of apigenin 23:742,748 of baicalein 30:289 of baicalin 30:289 ofbroussoaurone A 28:16,17 ofbroussoflavan A 28:16 ofbroussoflavonol F 28:17 ofbroussoflavonol G 28:4,17 of carotenoids 30:524 ofcassumunin A 23:845 ofcassumunin B 23:845 ofcassumunin C 23:845
56
of C-glycosylflavones 23:772 of chrysoeriol 23:742 of cyanidin 23:536,551,742,748 of diosmetin 23:742 of epigallocatechin 23:772 of epigallocatechin gallate 23:742,770,772 of flavonoids 26:765 of garlic 23:771 of Ginkgo biloba L. 28:179 of herbal drugs 25:44 of Hernandia moerenhoutiana 30.'561 of Hernandia voyronii 30.561 of isoorhamnetin 23:742 of isorhamnetin 23:748 of kaempferol 23:742 of kaempferol 3-O-(2"-[3-Dxylopyranosyl)-c~-Lrhamnopyranoside 28:64,65 of kaempferol 3-O-c~-Lrhamnopyranoside 28:64 of Licania licaniaeflora 28:63 of lignans 23:773 of luteolin 23:742,772 of malvidin 23:742 of menadione 30:321 of myricetin 23:742 of natural flavonol 30:224 ofoleanolic acid 23:535 of orcinol 30:173 of peonidin 23:742 of petunidin 23:742 ofphylloquinone 30:321 ofpolyphenol derivatives 30:224 of polyphenols 23:773;28:257, 293;30:224 ofpropylgallate 23:772 of quercetin 23:742 of quercetin 3-O-c~-Larabinopyranoside 28:64 of quercetin 3-O-a-Lrhamnopyranoside 28:64,65 of quercetin 3-O-f3-Dgalactopyranoside 28:64 of quercetin-3-O-ot-Lrhamnopyranoside 28:64 ofresveratrol of 23:534
of synthetic pharmacological agents 30:224 of tannic acid 23:395 of tannins 23:442 of taxifolin 3-O-cx-Lrhamnopyranoside 28:64 of ubiquinone 30:321 of wogonin 30:289 Antioxidant anthocyanidins 23:742 Antioxidant flavan-3-ols 23:743 structures of 23:743 Antioxidant flavonols 23:742 Antioxidant hydroxycinnamic acid 23:744 structures of 23:744 Antioxidant hydroxycinnamic acid 23:744 structures of 23:744 Antioxidant phenolic metabolites 23:739-795 biosynthesis of 23:740 changes during postharvest storage 23:739-795 changes during processing 23:739-795 from fruits 23:739-795 from vegetables 23:739-795 general structures of 23:740 Antioxidant properties 23:739;25:919, 930,935 of flavonoids 23:739 in apples 745 in apricot 23:745 m cherry 23:746 in citrus 23:747 m grapefruit 23:747 m grapes 23:748 in lemon 23:747 in olive 23:749 m orange 23:747 in peach 23:749 in pear 23:750 in plums 23:750 in raspberry 23:750 in strawberry 23:752 Antioxidative activity 23:342 of tannic acid 23:342 Antiparasitic activity 23:359,473; 26:800,817,819
57
of allicin 23:473 of coumarin 23:335,356,357, 353,368,376,393,550,553 with chalcones 26:800 Antiparasitic properties 30:741 family compositae 30:741 Anti-pathogenic phytoalexin compounds 25:652 Anti-peptide ulcer effect 25:430 of Chlorella vulgaris strain CK 22 (CVs) 25:430 Antiperiplanar orientation 14:457 Antiperoxidative effects 26:249-255 of lignans 26:249-255 Antiperspirant 26:398 Antiphlogistic 17:451 Antiphlogistic activities 21:633 Antiphlogistic drugs 22:114 Antiplamsodial naphthylisoquinoline 26:822 Antiplaque activity 21:613 Antiplasmodial activity 19:587; 26:788-800,805,806,808,810,813, 815,822-824,1035 ;30:596,597 in vitro 30:596,597 of chloroquine 30:596 of dioncopeltine B 26:822,823 ofdioncopeltine A 26:822,823 ofhervelines A-D 30:596 ofisoquinoline alkaloids 30:597 of laudanosine 30:596 of lignans 30:597 of reticuline 30:596 Antiplasmodial agents 20:525 Antiplasmodial flavonoids 26:801 Antiplasmodial phloroglucinol 26:797, 798 Antiplasmodic activity 21:584,614 Antiplatelet activity 23:364;30:594 of coumarin 23:335,356,357, 353,3 68,376,393,550,553 induced by PAF 30:594 of furofuran lignans 30:594 Anti-platelet aggregation activity 24:741 Antiplatelet aggregation effect 30:593, 597
in vitro 30:597 ofisoquinoline alkaloids 30:597 of lignans 30:597 Antiplatelet aggregation mrbidimetry assay 30:594 activity of Hernandia species in 30:594 activity of lignans in 30:594 in vitro 30:594 Anti-polio virus activity 30:411 of seaweeds 30:411 of Trichilia glabra 30:411 Antipredation 17:93 Anti-progression activity 30:593 Anti-proliferation 24:875 as biological action 24:875 Anti-proliferation action 24:875-925 of Kampo medicines 24:875-926 Anti-proliferation effect 30:313,495 against L1210 cells 30:313 of lc~,25(OH)zD 30:495 Anti-proliferative activity 7:419,422, 245,515;16:93 ;21:312;23:168; 23:168,180;26:485;28:17,145 ofbroussoflavonol F 28:17 ofbroussoflavonol G 28:17 ofdolastatin 10 28:145,649 of secosterols 23:168,180 Antiproliferative agent 23:472 Antiproliferative effect 12:393;23:361; 26:752;27:802,862 against HL-60 cells 12:393 against T cells 12:393 against BALB/C mouse 3T3 cells 12:393 against bovine brain cortex capillary 12:393 in Walker rat carcinoma cell 12:390 LzCB lymphocytes 12:393 mouse isolated microglia 12:393 NIH/3T3 fibroblasts 12:393 of 8-methoxypsoralen (8-MOP) 23:361 ofanticancer drug 12:390 ofcis platin 12:390 of endothelial cells 12:393 of human breast cancer 2R-75 cells 12:393
58 of human myeloid progenitor cells 12:393 of staurosporine 12:393 Antiprotozaol labdanes 26:810 Antiprotozoal activity 21:435 ;23:473; 26:452,780,795,797,798,810,825, 1060 of allicin 23:473 of sesquiterpenes 26:807 Antiprotozoal agent 26:230 (+)-nyasol as 26:230,231 Antiprotozoal anthraquinones 26:805 Antiprotozoal drugs 26:793 Antiprotozoal isoquinloines 26:821 from Annonaceae 26:821 from Berberidaceae 26:821 from Hernandiaceae 26:821 from Menispaermaceae 26:821 Antipsoriatic activity 30:323 against growth of human keratinocytes 30:323 of quinonic compounds 30:323 Anti-psychotic activity 24:1116 of selected natural products 24:1116 Antipyretic 30:825 properties of earthworm 30:825 Anti-pyretic action 24:55 Antipyretic activity 18:775;21:591; 26:1035;28:200 of genus Morus 28:200 Antiquorin 9:280 Antirachitic activity 30:484 of vitamin D analogues 30:484 Antirachitic factors 17:623 Anti-radical activity 28:257,293 ofpolyphenols 28:257,293 Anti-retroviral drugs 24:487,488 Anti-retroviral efficacy 30:628 by inhibition of protein-kinase Cmediated phosphorylation 30:628 of hypercin 30:628 Antirheumatic agent 30:292 Sideritis javalambrensis as 30:292 Anti-rheumatoidal effect 30:204 of hederaginin monodesmodides 30:204
Antirride 7:465,466 Antirrinoside 7:455,477 Anti-rubella activity 30:409 of dextran sulphate 30:409 of scleroglucan 30:409 of sulphate derivatives 30:409 Anti-secretory activity 24:799 biological activity 24:799 Anti-seizure activity 24:1111,1112 of selected natural products 24:1111,1112 Antiseptic agent 23:642 teucrium sp. as 23:642 Antiseptic lotion 30:159 resorcinolic lipids used as 30:159 Antiseptic-disinfectant 26:398 Antisera 15:368 Anti-serotonergic activity 24:799 Anti-sigs and anti CD40 25:272 Antispasmodic 22:346,525 Achyrocline satureioides as 22:346 Limnophila chinensis as 22:525 Antispasmodic activity 28:4,670 ofAgelas nakamurai 28:670 ofbroussoflavonol G 28:4 Antispasmodic agent 22:346,525 Achyrocline satureioides as 22:346 Limnophila chinensis as 22:525 Antispasmogenic activity 26:239 Antispasmolytic activity 23:544,591 Anti-stress activity 20:646 Anti-stress effects 28:177 of Ginkgo biloba L. 28:177 Antisweet activity 18:671,672 of gymnemic acid 18:671,672 Anti-thrombic action 30:70 of flavonoids 30:70 Antithrombogenic 30:841 role in EFE-immobilized polyurethane surface 30:841 Antithrombogenicity 30:841 Antithrombotic action 30:289,840 of baicalein 30:289 of baicalin 30:289 oflyophilized powder 30:840 Anti-tick activity 21:621
59 Anti-TNF- a 25:464 Anti-TNFa-antibodies 25:461 Anti-tobacco mosaic virus activity 23:73 Antitopoisomerase II 25:693 Anti-trichromonal agent 22:617 Antitrypanosomal activity (Trypanusosma cruzO 26:792 Anti-tubercluosis activity 20:712; 23:318 of natural quassinoid glycosides 23:318 Anti-tubercular activity 5:752,753 Anti-tubercular agents 5:751 Antitumor 30:69,160 extract of earthworm as 30:840 mechanisms of 30:69 Antitumor activity 1:275,316-320-408; 17:17;21:137,405,420,435,436,638, 704,733;22:676;23:74,96,126,132, 139,395,445,522,696,721; 24:272-275,288,845,847,849; 25:43,430,431,438,450-453;26:56, 482,706;27:803;28:211,517,519,559, 560,566 ;30:3,28,29,55,56,58,59,64, 65,224,314,395,589,690,777,840,841 against intraperitoneally (ip) inoculated leukemia 23:74 antitumor activity of 21:733 discodermolide as 30:3 in mice 30:160 in rumor-bearing animals 30:59 in vivo 30:28 of (-)-acetomycin 10:444,447 of (+)-5-epi-acetomycin 10:447 of acronycine 13:365-382 of ansamycin antibiotic 23:96 of ARS2 25:435,451 of benz[a] anthracene antibiotics 11:134 of carp oil 28:566;30:64,65 of celastraceae 30:690 of chitosan 28:560 of Chlorella vulgaris 25.'430, 431,450,452,453 of Chlorella vulgaris strain CK 30:777 of Coley's toxin 28:519 of cyanocycline A 10:103
of Dianthus superbus var. longicalycinus 26:56 of didemnins 10:254-257 of diphyllin 5:462 of fish oils 28:566 of fucoidan 30:56 of Ganoderman lucidum 30:58,59 of geldanamycin 23:96 of glycoprotein 30:841 of glycoprotein-rich substance 30:777 of glycosylated component 30:841 of glyfoline 13:375-380 of Hernandia species 30:589 of Hypericum genus 30:314 of indolo [2,3-a] carbazole alkaloids 12:390-396 of ingenol type diterpenes 24:288 of K-252a 12:394,395 oflignans 5:461 of lipids 28:517 of Magnolia officinalis 24:849 ofmaytansinoids 23:721 of morusin 28:211 of naphthocyanidine 1O:104 of natural products 28:559; 30:55,56 of neolignans 24:845,847,849 of nogalamycin 4:335 ofoleic acid 30:56 of pironetin 30:29 of Podophyllum 26:210 ofpolyphenols 30:224 ofpolysaccharide (PS) 30:395 o f pristimerin 5:747 of protein-bound [3-glucan 23:132 of quinocarcin 10:117 of rebeccamycin 12:394 of regelide 23:696 of regelin 23:696 of regelinol 23:696 of saframycins 10:78 of staurosporine 5:275; 12:390-394 of sterols 25:43
60 of tannic acid 23:395,445 of taxol 12:180 of tetrazomine 10:117 of triterpenoids 25:43;30:58,59 of triterpenoids in mice 30:59 of tubeimoside 21:733 oftubeimoside I 21:733 of tuna oil 28:566 ofUCN-01, UCN-02 12:395 of urdamycin 11:134 of verbascoside 23:522 of wilforlide 23:696 pironetin as 30:3 Anti-tumor agent 1:180,268,269;3:301, 383 ;9:383,385 ;23:829;24:1055,1085 Antitumor and/or antimetastatic activity 30:67 of carp oil effects on 30:66 of oleic acid effects on 30:67 Antitumor antibiotic 1:498-7215:592, 593;19:118 Antitumor bioactivity 30:841 from earthworm 30:841 Antitumor bioassay 9:383,386,401 Antitumor bisbolan sesquiterpenes 23:830 [3-atlantone 23:830 ~x-curcumene 23:830 r-turmerone 23:830 xanthorrhizol 23:830 Anti-tumor clerodane diterpenes 24:280-282 Anti-tumor compounds 24:269-350 Antitumor drugs 30:164 therapeutic action of 30:164 Antitumor effect 23: 107,115,123,126; 25:440;27:439 of carp extract 27:439 of glucan 23:107,115,123,126 of lentinan 23:130 Antitumor glycoprotein ARS-2 30:778 from Chlorella vulgaris strain CK 30:778 Antitumor immune response 26:921-923 Antitumor immuno-active glycoprotein 30:776 from Chlorella vulgaris strain CK 30:776
Antitumor immuno-activity 25:432 of Chlorella vulgaris strain CK 22 (CVs) 25:432 Antitumor immunopotentiation 25:454 Antitumor lignans 26:211 austrobailignans- 1 as 26:211 burseran as 26:211 (+)-dimethylisolariciresinol-2axyloside as 26:211
(-)-trans-2-( 3 ",4"-dimeth yo xyb enzyl)-3-(3 ',4 '-methylene dioxybenzyl) butyrolactone as 26:211 diphyllin as 26:211 diphyllin acetate as 26:211 justicin-D as 26:211 peltatins as 26:211 podophyllotoxins as 26:211 stegnangin as 26:211 stegnanol as 26:211 Antitumor mechanism 27:831 of guidimacrin 27:831 Anti-tumor metabolites 1:239 Antitumor plant product 23:71 Anti-tumor promoter 5:377;24:215-267 curcumin as 24:215-264 Antitumor promoter activity 21:585,705 Anti-tumor promoting activity 23:444, 670,841 of tannic acid 23:444 of tannins 23:444 Antitumor substance 28:569,570 egosterol as 28:570,572 from Agaricus blazei 28:569 isolation of 28:569 mechanism of 28:569 Antitumor therapeutic agent 30:840 Antitumor tubeimosides 21:730 Antitumor vascular inhibition 24:406 of phosphocombretastatin (Disodium salt) A-4 24:406 Antitumoral agent 30:691 for skin cancer 30:691 use of Maytenus amazonica 30:691 Antitumoral immune responses 26:923, 924,929 Antitumoral uses 30:732 of plants 30:732
61
Antitumorigenic agent 23:478 Anti-tumour-promoting activity 21:642; 24:215-264 ;25:46;30:695 Antitumour-promotor 25:44-46,60 antioxidant activites of 25:59 from herbal drugs 25:44 Antitumour activity 22:97-100,361 of 3',4-O-dimethylcedrusin 22:361 of friedelone 22:97-100 of hopane quassionoid 22:97-100 oflanostane lupane 22:97-100 of oleanane 22:97-100 Anti-tussive activity 17:633;28:200 of genus Morus 28:200 Antiulcer activity 22:410,419 Antiulcerative properties 21:410 Antivectorial activity 21:591 Anti-venom alkaloid 1:239 oxidation 1:239 Antiviral activities 5:461,563;10:608, 609,619,620;17:146;21:132,148, 150,393,435,600,615,662,690,718; 22:307,361 ;23:233,268,233,346,395, 473,512,531,703;25:114;26:169,222, 224,226,344,452,741,759;27:482; 28:257,293 ;30:224,324-326,393,394, 395,398,401-405,407,410-412,627, 742 against Herpes simplex virus 17:146 against HIV-1 30:398 against HIV-2 17:146;30:398 against HSV 30:401 against HSV-1 30:401 against plant virus infection 30:412 against sandfly fever sicilian virus (SFSV) 30:410 in cell cultures 30:394 in mouse models 30:405 in vitro 30:401,404,405 of (-)-aristeromycin 10:609 of (+)-C-2'-ara-fluoroguanosine 10:609 of 2-amino oxetanocin-A 10:620,621 of 3',4-O-dimethylcedrusin
22:361 of 3'-azido-3'-deoxythymidine 10:585 of aciclovir (9-[2-hydroxyethoxy)methyl] guanine 10:585 of allicin 23:473 of Astragalus brachycentrus 30:405 of Astragalus echianaeformis 30:405 of Astragalus membranaceus 27:482 of carbocyclic oxetanocin A and G 10:620,621 of carbovir 10:608,609 of carrageenans 30:410 of cationic polysaccharide (PS) 30:402 of D-2'-deoxycarbocyclic guanosine 10:608,609 of defensins 23:346 of dextran sulphate 30:410 of didemnins 10:253,254 ofeudistomin E 23:268 of flavonoids 17:145;22:307 of fucoidan 30:410 of Hernandia perforatum 30:407,627 of Ichyroclineflaccida 30:401 ofimidazole analogues 5:566 of lignans 5:461 of mannans 30:402 of marine organisms 5:359,364 ofmycalamide A 5:366 of Nothogeniafastigiata 30:404 of OGs 25:114 of oleanolic acid derivatives 17:135 of oxetanocin A 10:608,619,620 of oxetanocin G 10:619,620 of pentosan polysulphate 30:410 of Podophyllum extracts 26:169 of polyphenols 28:257,293; 30:224 ofpolysaccharides 30:393,395 of quinones 30:324-326 of quinovic acid derivatives 17:134 of resveratrol 23:531
62
of saikosaponins 23:512 ofSambucus nigra 30:407 ofSaponaria officinalis 30:407 of spermidine 5:563 of Sterculia urens Roxb. 405 of sulphated galactan 30:402 of sulphated polysaccharide (PS) 30:403 of tannic acid 23:395 of Theonella sp. 5:364 of verrucosin 26:228 of xylogalactans 30:402 of yeast mannans 30:412 of [3-carboline alkaloids 23:233 on infected vero cells 30:410 Antiviral activity 30:405 of tragacanthin polysaccharide (PS) from 30:411 Antiviral agent 19:351,511 ;24:474-555; 30:394,399,402,405,408 acyclovir as 24:474,486 cidofovir as 24:486,487 didanosine as 24:474,486,488 forscarnet as 24:486,487 from calcium spirulan as 30:399 fucoidan as 30:405 ganciclovir as 24:474,486 in vitro as 30:408 in vivo testing of as 24:491 lamivudine as 24:488 sorivudine as 24:474,486 stavudin as 24:474,486,488 sulphated phyto-PS as 30:402 trifluridine as 24:487 zalcitabin as 24:474,486,488 zidovudine as 24:474,486,487 Antiviral antibiotic 21:407 Antiviral chemotherapy 30:394 Antiviral compounds 24:492-544 alkaloids 24:527-533 buntenolides 24:521,522 carotenoides 24:533-540 chromones 24:499-503 coumarins 24:499-503 iridoids 24:510-521 lignans 24:503-509 macrolides 24:541-544 marine-derived 24:526-543 N-containing compounds
24:527-533 nucleosides 24:527-533 peptides 24:522,527-533 phenolics 24:503-509 phenyl propanoids 24:503-509 phospholipids 24:521,522 polyacetylenes 24:521,522, 541-544 polysaccharides 24:540,541 prostaglandins 24:541-544 proteins 24:522,527-533 pyrones 24:541-544 quinone 24:503-509,541-544 steroids 24:510-521,533-540 tannins 24:510-521 terpenes 24:510-521 terpenoids 24:533-540 thiophenes 24:521,522 xanthones 24:503-509 Antiviral drugs 30:742 Antiviral effect 23:135;30:627 of [3-glucans 23:135 of hypericin 30:627 mechanism of action of 30:627 Antiviral efficacy 30:408 of natural polysaccharidic-related materials 30:408 of pine cone extract 30:408 Antiviral factor (AVF) 24:524 Antiviral glycopeptide 24:524 meliacin as 24:524 Antiviral microbial-derived compounds 24:544-555 actinomycin D 24:547 ansamycin 24:545-546 aphidicolin 24:549 bleomycins 24:547,548 cardyceptin (3 '-deoxyadexosin) 24:547 cytochalasins 24:549 distamycins (pyrrole amidines) 24:546 dounomycin 24:547 doxorubicin 24:547 filipin 24:548 gliotoxin 24:545 mithramycin 24:547 mycophenolic acid 24:549 rifamycin-type macrolides
63
24:545,546 sinefungin 24:547 toyocamycin 24:547,548 Antiviral polyanionic properties 30:404 Antiviral properties 30:407409 of polymeric carbohydrates 30:409 ofpolysaccharide (PS) 30:407 Antiviral protein 13:655 Antiviral screening 30:411 Antiviral screening assays 24:484,490 in vitro 24:484,490 Antiviral substances 30:394,395 from plant kingdom 30:395 from plants 30:394 Antiviral sulphated polysaccharide (PS) 30:408 Antiviral treatments 30:407 Anti-vitamin activity 9:519 of 25-aza-vitamin D3 9:519 Anti-ct-D-mannose antibodies 29:559 against Staphylococcus aureus 29:560 in hormone therapy 29:561 in serological development 29:560 in vaccine production 29:560 Ants 6:434-444 chemical defense in 6:421-465 pipeidine alkaloids in 6:422-434 pyrrolidine venom alkaloids in 6:434-444 Anxiety 30:368 role of serotonin (5-HT) in 30:368 Anxiolytic activity 28:177 of Ginkgo biloba L. 28:177 Aokumanol 23:815 Aopinolide 23:813 synthesis of 23:813 Apaenogaster rudis 5:254,255 Apergillus oryzae 18:807 monohexosylceramides from 18:807 Aphaenogaster longiceps 5:252 Aphanamyxis sp. 21:124 Aphanizomenon flosaquae 26:353 Aphanizomenon sp. 26:352,358 Aphanocapsa feldmanni 21:367
Aphanomyces 22:493 Aphanomyces cochlioides 22:482 Aphanomyces euteiches 22:482 Aphanomyces raphani 22:482 Aphelandra tetragona 27:191,193 Aphelasteriasjaponica 15:69 Aphelasteroside A and B 15:68
Aphelencoides besseyi 26:434,436, 439,465,469
Aphelencoides tritici 26:438,469 Aphid antifeedant activity 23:304 ofbrucein B 23:304 ofisobrucein A 23:304 of quassin 23:304 Aphid antifeedants 23:304 quassinoid activity as 23:304 Aphidicolan-type diterpenoids 21:694 Aphidicolin 14:583;21:136,721; 22:217,234;24:549 antiviral microbial-derived compound 24:549 Aphidicolin-17-glycinate 22:235 Aphidius rhopalosiphi 27:213 Aphis gossypii 23:666 Aphomia melleus 15:387 Aphomia oniki 15:383 Aphomia sociella 15:384 apigenin-7-O-glucoside from 28:167 bilobetin from 28:166 biological activities of 28:165 chemistry of 28:165 delphidenon from 28:167 ginkgetin from 28:166 ginkgolide A from 28:170 ginkgolide B from 28:170 ginkgolide C from 28:170 ginkgolide J from 28:170 ginkgolide M from 28:170 isoginkgetin from 28:166 isorhamnetin from 28:167 isorhamnetin-3-O-glucoside from 28:167 isorhamnetin-3-O-rutinoside from 28:167 kaempferol from 28:167 kaemp ferol- 3- O-(2"- Oglucosyl)rhamnoside from 28:167
64
kaempferol-3-O-(6"'-O-pcoumaroyl-2"-O-glucosyl) rhamnoside from 28:167 kaemp fero 1-3-O-[ 6" '-O- {p-(7 ....O-glucosyl)coumaroyl}-2"-Oglucosyl]rhamnoside from 28:167 kaempferol-3-O-[c~-rhamnosyl( 1---~2)- c~-rhamno syl- ( 1~ 6)]- [3glucoside from 28:167 kaempferol-3-O-glucoside from 28:167 kaempferol-3-O-retinoside from 28:167 kaempferol-7-O-glucoside from 28:167 luteolin from 28:167 luteolin-3'-O-glucoside from 28:167 4-O-methylpyridoxine from 28:172 myricetin from 28:167 myricetin-3-O-rutinoside from 28:167 quercetin from 28:167 quercetin-3-O-(2"-O-glucosyl) rhamnoside from 28:167
quercetin-3-O-(6"'-O-p-
coumaroyl-2"-O-glucosyl) rhamnoside from 28:167 quercetin-3-O-[6"'-O- {p-(7 ....-Oglue o syl) c oumaroyl }-2"- Oglucosyl]rhamnoside from 28:167 querc etin- 3-0-[ 6" ' - O-p- c o umaroyl-2"-O-glucosyl) rhamnosyl-7-O- glucoside from 28:167 quercetin-3-O-[c~-rhanmosyl( 1---~2)- ~-rhamno syl-( 1-~ 6)- [3glucoside from 28:167 quercetin-3-O-glucoside from 28:167 quercetin-3-O-rhamnoside from 28:167 quercetin-3-O-rutinoside (rutin) from 28:167 sciadopitysin from 28:166
API 29:591 effects on cathepsin D 29:591 Apiaceae 21:615 Apicomplexan 26:804 Apicularens 25:728 Apiculture 28:390 acaricides in 28:390 Apidae 6:421 Apigenin 22:423,438;25:541,544,594; 26:746,750,763,802;29:572;30:284, 725,727 effects on HIV-1 protease 29:572 effects on aminopeptidase N 29:577 ~H-NMR data of 30:284 structure of 30:725 Apigenin 7-glucoside 23:342 Apigenin 7-rutinoside 23:747 Apiguard 28:391 for thymol-based acaricide 28:391 Apiin 25:595 Apilife VAR 28:391 as Frakno thymol frame 28:391 c~-Apiodionen 28:117 as topoisomerase inhibitor 28:117 [3-Apiodionen 28:117 as topoisomerase inhibitor 28:117 D-Apiofuranosyl 15:7 Apioglycyrrhizin 15:26 Apiosordaria effusa 28:117 Apiospora montagnei 21:216 apiosporamide from 21:216 Apiosyl glucosides 5:643 Apis mellifera 28:387,393 Apium graveolens L. 22:512;29:83,573, 581,589 Apium sp. 27:686 Apiyski brasiliana 25:702,717,785,801 Aplasmomycin 21:316 Aplasmomycin B 19:587 Aplasmomycin C 19:587 Aplidites A-G 19:617 Aplidium albicans 27:804 Aplidium californicum 10:248;18:716 Aplidium cavernosa 10:248
65
Aplidium constellatum 10:248 Aplidium genus 25:837 Aplidium meridianum 25:764 Aplidium multiplicatum 23:185,196 Aplidium pliciferum 23:235;28:635 Aplidium sp. 5:440,617;10:244,248 Aplidium uouo 28:644 Aplinia sp. 17:358 Aplydilactone 17:6 Aplykurodin A 17:5 Aplyronines A-C 19:609 cytotoxic activities of 19:609 Aplysia brasiliana 6:6;9:249;18:625 Aplysia dactylomela 5:368;6:35;17:7, 8,430 Aplysia faciata 17:6 Aplysia fistularis 25:787 Aplysiajuliana 17:6 Aplysia kurodai 6:24,56;17:4,6;28:648 Aplysia punctata 17:9;25:769 Aplysia sp. 5:368;25:724 Aplysiapyranoid A-D 17:5 Aplysiatoxins 18:294,549 Aplysilla glacialis 17:14,15 Aplysilla rosea 6:107 Aplysilla sulphurea 17:11 12-epi-Aplysillin 17:12 Aplysillin 6:107,109 Aplysillin A 28:697 as thrombin receptor antagonist 28:697 Aplysina aerophoba 21:259,260;25:712 aerophobin-1 from 21:259 isofistularin-3 from 21:259 Aplysina archeri 25:720 Aplysina cauliformis 25:766 Aplysina fistularis 17:103;21:307,308; 26:86;28:697 Aplysina sp. 25:17,707 Aplysinopsine 5:410;23:258 cytotoxic activity of 5:410 Aplysiotoxin 25:771 (-)-Aplysistatin 16:705 antineoplastic agent 16:705 Apo-carotenoids 30:516,528,540 stretching vibrations in 30:540 Apocynaceae 21:3,129;25:249 Apogen 22:44 Apollonias barbujana 26:850
Apomorphine-binding sigma receptors 25:538 f3-Apopicropodophyllin 26:193 ;213,214 cytotoxicity of 26:213 immunosuppressive activity of 26:214 Apoplastic fluids 25:400 Apoprotein 30:534 X-ray data of 30:534 Apoptic body formation 25:466 Apoptosis 22:444;25:268,269,272; 26:752,922,925,993,1262,1264, 1289;27:86-88;28:175 in cerebellar granulosa cells 25:269 in primary granulosa cells 25:269 in susceptible Burkitts lymphoma (BL) 25:272 in viral infections 24:478-480 ofbilobalide 28:175 of ginkgolide B 28:175 of ginkgolide J 28:175 relation with lipid peroxidation 27:86-88 role of 3-(4,5-dimethylthiazol-2yl)-2,5-diphenyl tetrazolium bromide 28:175 role of cerebellar granule cells 25:268 Apoptosis 23:497;26:752,922,925,993, 1262,1264,1289 Apoptosis-inducing activity 23:97 on human leukemia 23:97 Apoptotic bodies 25:469 Apoptotic bodies formation 25:468 Aporphine alkaloids 21:68;25:544 apomorphine 25:544 boldine 25:544 Aporphine isoquinoline alkaloids 25:527,530,543 xylopinine 25:530 isocorydine 25:530 Aporphines 21:57,73,79;22:19,22 Appetite suppression 30:194 due to opioids 30:194 Apple dihydrochalcones 23:744 Application 27:322 ofabscisic acid 27:322
66
of cholelithiasis 27:382 ofcyclodextrins in GC 27:368 Aprotinine 24:524 as protease inhibitor 24:524 Apuleia leiocarpa 5:679,680 Apulein 5:680 Apuleisin 5:680 Apurinic sites 22:27 Aquafoliacese 9:402 Aquillochin 5:5,6,8 Aquillochin diacetate 5:7-9 APT spectrum of 5:7 ~3C-NMR spectrum of 5:9 ~H-NMR spectrum of 5:9 selective INEPT spectrum of 5:9 Ara-A 21:252 Arabidopsis 25:368,391,395,413,422, 426,660 Arabidopsis cultivar 25.418,419; 26:933,1289 mutant detz 25:419 mutant saxl 25:418 Arabidopsis dwarf 25:414 Arabidopsis genes 25:414 mutated 25:414 Arabidopsis thaliana 18:721 ;25:377, 385,496;26:478,945,948,1268,1289; 27:322,331 ;29:59,603,607,612,613 Arabino-2-hexulopyranose 15:190 DArabinofuranose 6:352,335 Dphosphorus analogs of 6:352,335 Arabinogalactan 26:1156 Arabinogalactin 15:36 Arabinoglucoronopyranosides 7:435 ofoleanolic acid 7:435 Arabino-hexofuranose 6:376 DC6-P bond analogs of 6:376 L-Arabinopyranosyl 15:7 3-O-[cx-L-Arabinopyranosyl (1---~2)-[3D-glucopyrano-syl]-3 [3,713,18,20,26pentahydroxy-(20S)-damunor-24ene 21:733 L-Arabinopyranosyl unit 15:21 c~-L-Ar ab inop yrano syl- ( 1---~2)- [3-Dglucopyranosyl 21:732 3-O- [a-L-Arabinopyranosyl-(1 ~2)-13D-glucopyrano-syl-]-bayogenin-28-
O- [c~-L-rham-nopyranosyl-(1 ~2)-aL-arabinopyranosyl] ester 21:732 D-Arabinose Arabinose 7:136,139;22:312;23:163; 30:433 reaction of 30:433 L-Arabinose 7:144,181,294,298;11:7,8; 30:452 allylation of 30:452 Arabinosidasic 24:994-998 enzymatic activity 24:995-998 3-Arabinoside 23:745 Arabinosyl cobaltoxime 30:449 Arabofuranosides 5:657 Araboglycyrrhizin 15:26 Arabopyranosides 5:657 Arabsin 7:231 Arachidonamide 9:582 Arachidonate 5-1ipoxygenase 28:216 Artocarpus flavonoids against 28:216 Arachidonate 5-1ipoxygenase activity 28:216 of artonin E 28:217 of morusin 28:217 Arachidonate oxygenase activity 28:217 Arachidonate-5-1ipoxygenases 29:672 adjusting immune response 29:672 as chemotactic agents 29:672 in B lymphocytes 29:672 m basophils 29:672 in eosinophils 29:672 m macrophages 29:672 in mast cells 29:672 m monocytes 29:672 m polymorphonuclear leukocytes 29:672 inducing cell adhesion with 29:672 origin of 29:672 Arachidonic acid 21:657,744;25:66, 263,274,275,333,596,597,616,66; 26:758,759;27:422;30:192,225,594 from phospholipids 27:422 inhibition of 25:66 leukotrienes from 30:225 metabolism of 26:265-268
67
platelet aggregation induced by 30:594 Arachidonic acid cascade 22:434 Arachidonic acid induced edema 25:46 inhibition of 25:47 Arachidonic acid metabolism 20:514; 27:693 Arachidonic acid methyl ester 2:12 CI(NO) mass spectrum of 2:12 Arachiniodes exilis 27:35 Arachiniodes sporadosora 27:35 Arachis hypogaea 25:93;29:598 Arachnida 28:382 class of 28:382 Arachniodes exilis 15:33;27:18,35 Arachniodes sporadosora 15:33; 27:18,35 Arachnoideum sp. 26:685 Aralia continentalis L. 22:512 Aralia elata 21:655,666;24:273 triterpene saponins from 21:655 Araliopsis tabouensis 2:121 Araneosol 7:226 Araucaria bidwilli 25:249 Araucaria cookii 17:36 Araucaria cunninghamii 17:36 Araucaria excels 25:249 Arbacia lixula 15:104 Arbacia punctulata 7:303 Arbiglobin 7:234 Arbol negro 23:657 Arborescidimes A 23:263 (+)- l, l O-epi-Arborescin 14:365,366 Arborinane 25:54 Arbortristosides A&C 26:807 Arbus cantoniensis 25:91 Arbusculin A 27:549 Arbusculin A-D 7:231,232 Arbusculin E 7:234 Arcanose 4:255 Arcapillin 7:226 Archaebacteria metabolism 25:939 Archangelicin 23:351 Archaster typicus 7:304-306;15:74,84 Archniodes sporadosora 27:35 (-)-Arctigenin 24:742 Arctigenin 5:522;26:192,217,218,233, 241,269 as PAF-induced inhibitor 26:241
of methyl ether 26:192,241 Arctigenin 4'-O-glucoside 5:490,491 Arctigenin methyl ether 26:241 as PAF-induced inhibitor 26:241 Arctigenin monoacetate 18:601 Arctiin 5:475,476,489-491,522;26:192, 237 Arctium lappa 5:497;26:217,233,241 ; 25:944 arctiin from 26:217 arctigenin from 26:217 Arctomecon genera 27:163 Arcyria cinerea 29:236 Arcyria denudata 5:55;21:263;29:225, 236 arcyriaflavin from 21:266 arcyriaflavin-B from 12:366,370 arcyriaflavin-C from 12:366,370 arcyriarubin A from 12:366,370 arcyriarubin B from 12:366,372 arcyriarubin C from 12:366,372 arcyriaverdin C from 12:366,372 arcyoxepin A from 12:367,373 arcyroxepin B from 12:367,373 arcyroxindole A from 12:367, 372 arcyroxocin B from 12:367,372 dihydroarcyriarubin B from 12:366,370 Arcyria feruginea 29:258 arcyriarubin C from 12:366,372 Arcyria natans 29:236 arcyriacyanin A from 12:366, 372 arcyriaflavin-A from 12:366,370 arcyrioxocin A from 12:367,472 dihydroarcyriacyanin A fi-om 12:367,372 Arcyria sp. 12:367,373 arcyrin A from 12:367,373 arcyrin B from 12:367,373 Arcyriaflavin B 5:55,56 Arcyriaflavin C 1:3;5:55,56 Arcyriaoxocin A 29:227 against human cancer cells 29:229 against protein kinases 29:229 biological activity of 29:229 for anticancer drugs 29:229
68
mode of action of 29:229 synthetic routes to 29:227 Arcyrin arcyrinin model compounds 12:383 from N-methylarcyriarubin A 12:383 synthesis of 12:383 Arcyrinin B 12:367,373 Arcyroxepin B 12:367,373 Arcyroxindole A 12:367,373 Arcyrioxocin A 12:367,372 Arcyroxocin B 12:367,372 Ardeola ibis 5:837 hemoglobin components of 5:837 Ardisia colorata 30:161 cytotoxic activity of 30:161 effect on FM3A cells 30:161 Ardisia crenata 26:8 Ardisiajaponica 13:660;17:117,127 Areca catechu 13:660;24:272;29:578 arecoline from 13:660 Areca II-5-C (tannin) 29:578 effects on ACE 29:578 Arecaidine 21:84 Arecoline 22:17,736 Arecoline sp. 25:530 Arelia cordota 20:690 Arenaria filicaulis 26:52 Arenaria kansuensis 18:721 Arenarol 5:458;15:315 Arenarone 5:438 cytotoxic activity of 5:438 Arenastatain A 25:714,717 Arenavirus replication 30:412 inhibitory effect on 30:412 Arene carbene 3:324,325 Arene-metal n-complexes 20:310-312 Arene-olefin metaphotocycloaddition 3:14 Arenes 27:749,754 hydroxylation of 27:749,754 microbial oxidation of 18:430-432 Arenesulphonyl-5-(pyridine-2-yl)tetrazolides 13:275 Arg557-Ile558 30:838 Arg-D-Trp-NmetPhe-D-Trp-Met-NH2 27:799
as anticancer peptide 27:799 Argemone genera 27:163 Argemone mexicana 26:435 Argentation chromatography 9:450,460, 464,465 Argentation TLC 9:333,338,343 Argentilactone 19:463,494 Argentinian Baccharis spp. 30:730 structure of 30:730 Argentiolide A 7:211,231 Argentiolide B 7:230 Arginine 22:390 Arginomonas non-fermantans 25:155 Arglanilic acid methyl ester 27:557 Arglanine 7:232,234;27:549 Argogorytes fargei 5:225,250,253 Argogorytes mystaceus 5:225,231, 252,253 Arguticinin 5:202,203;9:66 Argutinin 5:203;9:66 Argylioside 7:443 Aricine 9:174 Arisaema amurense 22:512,513 for convulsions 22:513 mrisaema amurense vat. serratum 22:512 as anticonvulsant 22:512 Arisaema consanguineum 22:512 for convulsions 22:512 Arisaema grammicola 22:579 Arisaema heterophyllum B. 22:512 for epilepsy 22:512 Arisaema heterophyllum B. 22:512 for epilepsy 22:512 Arisaemajaponicum 22:513 Aristea ecklonii 2:224 Aristeguetia bulleaefolia 25:251 (-)-Aristeromycin 10:609 antiviral activity of 10:609 Aristeromycin 8:140 Aristlane 18:607 Aristocarbinol 9:172 Aristolasicol (aristotelin- 19-ol) 9:172; 11:305,312 Aristolasicone 9:172 9-Aristolene 23:162 Aristolochia argentina 19:494
69
Aristolochia indica 22:27 aristolactam-N-beta-D-glucoside from 22:27 Aristolochia spp. 21:97 Aristolochic acid 21:97 Aristolone 20:464 (-)-Aristomakine 11:301,302 (-)-Aristomakinine 11:301,302 relative configuration of 11:301-303 Aristone 11:277 Aristoserratine 9:171 (+)-Aristoserratine (aristotelin- 15-one) 11:296 absolute configuration of 11:296 X-ray crystallography of 11:296 Aristotelia australasica 11:293,317 allo-aristoteline (epi- 11aristoteline) from 11:317 aristolasicone from 11:312 (+)-aristoserratenine from 11:293 3-epi-aristoserratenine from 11:293 Aristotelia fruticosa 11:278,324 (+)-aristofruticosine from 11:324 (+)-fruticosonine from 11:278 Aristotelia serrata 11:278,296,301 (-)-aristomakine from 11:301 (-)-aristomakinine from 11:301 (+)-aristoserratenine from 11:293 (+)-aristoserratine from 11:296 (-)-hobartine from 11:278 8-2H-Aristoteline 11:311 Aristotelone 11:321,322 Aritason 20:13 Arjunglucoside 1 23:515 Arjunic acid 7:133,134 glycosides of 7:133,134 from Terminalia alata 7:134 Arjunosides I-IV 7:133 from Terminalia arjuna 7:133 [3-ARK I 21:264 Arlatin 7:234 Armefolin 7:232;27:550 Armexifolin 7:232 Armexine 27:550
Armillaria mellea 5:289,290;22:513 Armillaria nova zelandiae 21:196 Armin 7:232 Army worm (Spodoptera frugiperda) 14:451 Arndt-Eistert homologation 1:237; 13:116 Arndt-Eistert reaction 13:79,93 Arnica acaulis 29:90 Arnica chamissonis 29:90 Arnica montana 26:808;29:90 Arnica spp. 29:577 Arnicenone 3:6,60 Arnidoil 22:122 Aromadendrane 14:355;15:227;18:607 Aromadendrane 25:848,850 (+)-4-epi-Aromadendrene 14:359,362 Aromatase inhibitor 28:16,17 albanol A as 28:17 broussoflavonol F as 28:17 broussonin A as 28:16 demethylmoracin I as 28:18 Aromatic acetylenes 7:222 Aromatic alkaloids 23:233-283 Aromatic amines 27:749 oxy-functionalization of 27:749 Aromatic aminoacids 23:240 metabolites of 23:240 Aromatic chromophores 2:171,172; 12:46,47 Aromatic compounds 6:509;23:638 oxidation of 6:509 Aromatic L-amino acid decarboxylase (AADC) 30:370,380 activity in metabolic pathways 30:380 Aromatic phosphoramidates 14:286 Aromatic triterpene 30:682 species of 30:682 pristimerin 30:682 tingenone 30:682 Aromatization 7:360-363;11:114-119; 27:782 of N-heterocyclic ring 27:782 Arossostephium chinese L. 22:518 [3-Arotene monocation 30:548 structure of 30:548 Arrabidaea platyphylla 22:513 for epilepsy 22:513
70
Array processor 2:113 Arrow poisons 12:233 ARS2 25:435,451;30:776 antitumor activity of 25:438,451; 30:776 effect on enzyme hydrolysis 30:777 effect on periodate oxidation 30:777 ARS-2 mediated cellular activation 30:781 Arscotin 7:224 Arsenic-containing ribofuranosides (ACRs) 25:867 Artabin 27:558 Artabortrine 20:480,481 Artabotrys zeylanicus 20:480 dioxoaporphines of 20:480 Artabsin 7:234;27:575 Artabsinolide A-D 7:234 Artabsinolide B 7:209,210,234 Artanin 7:204,205,224 Artanomalolide 7:239 Artausin 7:234 Arteannuin B 7:217;22:153 from Artemisia annua 7:217 Arteannuinic acid 7:238 Arteanoflavone 7:226 Arteanomalactone 7:230 Artecalin 27:550 Artecanin 27:575 Artecanin hydrate 7:234 Artedouglasia oxides 9:531-533 Artedouglasia oxides A-D 7:217,218 Arteether 22:154;26:833 Artefransin 7:234 Arteglasin A 27:575 Arteglasin A,B 7:234 Artelin 7:225 Artelinate 26:833 Artemether 22:154;26:832,833 Artemetin 7:206,226 Artemia salina 9:385,387;21:257; 22:577,629;23:170;26:703 Artemidin 7:203,223 Arteminolide 24:457 FPTase inhibition by 24:403-464
Artemisia abrotanum 7:205,218,240 coumarin-sesquiterpene ethers in 7:205 Artemisia absinthium 7:215,219,220, 240;28:425,426 absinthin from 7:215 acaricidal activity of 28:425 against aphids 28:425 as insecticide 28:425 Artemisia alcohol 9:530 Artemisia annua 22:146;26:363,783, 801,831 artemisinin from 13:657;20:518 arteannuin B from 7:217 candinane derivatives from 7:217 Artemisia anomala 7:215,240 aurantimide acetate from 7:220 simiarenol from 7:218 Artemisia aragonensis 7:212 Artemisia arborescens 27:376 Artemisia arbuscula 7:208 arbusculone from 7:208 Artemisia argyi 7:218 simiarenol from 7:218 Artemisia aucheri 7:208,241 Artemisia austriaca 7:241 C-methylflavone in 7:207 Artemisia californica 20:4 Artemisia cantabrica 7:216,242 Artemisia capillaris 7:220,242;23:341 Artemisia carvifolia 7:206,242;29:574 Artemisia compacta 7:205,243 Artemisia douglasiana 7:203,204,217, 218,243;29:90 Artemisia dracunculus 7:220,243; 29:577 Artemisia feddei 7:208 filifolide A from 7:208 filifolone from 7:208 Artemisia fragrans 7:208,244 Artemisia genus 27:376 Artemisia glutinosa 7:220,244 Artemisia gypsacea 7:211,245 Artemisia herba alba 7:212,217,245; 17:475 ;24:65,79 ;27:376 Artemisia hispanica 7:216 elemanolide from 7:216 2ot-hydroxyartemorin from
71 7:211 tamaulipin A from 7:211 Artemisia inculta 7:217,245 Artemisia iridentata ssp. rothrockii 7:208,252 Artemisiajudaica 7:211,216,217,246; 27:376 Artemisia klotzchiana 7:214,246 Artemisia koidzumii 7:218,246 Artemisia laciflora 7:203,218,246 Artemisia laciniata 7:215,216,246; 9:529,531,533-535 Artemisia lanata 7:214,246 Artemisia latifolia 7:219,247 Artemisia leucodes 7:215,247 Artemisia longloba 7:218,247 Artemisia ludoviciana 7:203,247;29:87 Artemisia maritima 7:217,427;13:660; 24:54,77 Artemisia marschalliana 7:220,248 Artemisia molinieri 7:218,248 Artemisia monosperma 7:204,220,248 Artemisia montana 25:944;27:418 Artemisia montana extracts 27:420 biological activity of 27:420 Artemtsza moorcrofiiana 9:529,530,534 Artemtsta pallens 7:217,249;9:531 Artemtsta palustris 7:207,220,249 Artemisia pectinata 7:214,216,249 Artemisia persica 7:217,249 Artemtsta princeps 25:944;27:418; 29:87 Artemisia roxburghiana 7:219,250 Artemisia rupestris 7:218,250 Artemista rutifolia 7:215,250 Artemisia salsolodes 9:529-531,533,534 Artemisia santolina 7:212,250 Artemisia santonicum 7:212,250 Artemisia schmidtiana 14:450 eudesm-11-en-4-ols from 14:450 neointermedeol from 14:450 Artemisia selengensis 7:203,204, 215,251 Artemisia sp. 7:201-263;9:529-536; 25:944 ;27:418,847 ;29:88,580 Artemisia szowitziana 7:216,251 Artemisia toumefortiana 7:212,252; 24:79 Artemisia tridentata 28:408
Artemisia umbelliformis 7:215,253 Artemisia valentina 7:213,218 Artemisia verlotorum 22:513 Artemisia vulgaris 7:120,208,215, 218,253 Artemisia xanthochroa 7:215,253 Artemisin 24:77 Artemisinin 23:488;26:363,446,779, 783,807,809,811,825,832-834,840 Artemisiten 22:161 Artemorin 7:209,210,230;27:558 Artemorin-4ot,5 [3-epoxide 27:558 Artenolide 7:239 Arterial thrombosis 30:593 due to platelet aggregation 30:593 Arteriosclerosis 30:55,56,58,70 Ganoderman lucidum in treatment of 56,58 prevention of 30:56 role of natural products in 30:55 use of Laminaria japonica Aresch in 30:56 Artery constriction 30:55 Artery relaxation 30:72 by chalcones 30:72 Artesieversin 7:239 Artesin 7:212,213 11-epi-Artesin 7:213 Artesovin 7:216 from Artemisia szowitzian a 7:216 Artesunate 26:833 Artevasin 7:230 Arthricular synovial membrane 30:689 inflammation of 30:689 Arthritis 26:50;30:58,193 Ganoderman lucidum in treatment of 30:58 Herniaria hirsuta in 26:50 use of capsaicin in 30:193 Arthrobacter globiformis 9:418;
26:1263,1268-1270,1272,1278-1280
Arthrobacter ilicis 25:719 Arthrobacter simplex 9:418,427,428 Arthrobacter sp. 26:1122,1124 Arthrobotrys oligospora 26:431,432, 449
72 Arthropod alkaloids 11:231 from Solenopsis sp. 11:231 Arthropod ectoparasites 12:7 Arthropoda 19:627 Arthropod-borne diseases 28:394 of humans 28:394 of livestock 28:394 zoonotic as 28:394 Artichoke phenolics 23:753 Articulin 30.'708 structure of 30:708 Articulin acetate 30:734 cytotoxic activity of 30:734 Artificial electron mediators 20:821-824 Artimisinin 25:350 Artobiloxanthone 28:201,229 biological activity of 28:229 from moraceous plants 28:201 Artocarpesin 28:201 from moraceous plants 28:201 Artocarpus altilis 28:202 Artocarpus communis 28:202;29:706 Artocarpus elasticus 29:790 Artocarpus flavones 28:216 5-1ipoxygenase activity of 28:216 Artocarpus flavonoids 28:203,216,220 against arachidonate 5-1ipoxygenase 28:216 against TNF-c~ release 28:220 Artocarpus heterophyllus 22:513; 27:842 ;28:202 ;29:580 as sedative for convulsions 22:513 Artocarpus nobilis 2:231 Artocarpus rigida 28:202 Artocarpus sp. 28:203 Artocarpus venenosa 28:202 artobiloxanthone from 28:202 artonin E from 28:202 cycloartobiloxanthone from 28:203 isoprenylated flavonoids from 28:202 use against inflammation 28:202 use in malarial fever 28:202 use as folk medicine 28:202 use in malarial fever 28:202
Artonin E 28:201,215,229 as 5-1ipoxygenase inhibitor 28:215 biological activity of 28:229 Arugomycin 19:118 Arusgospongines A,B,C,D.E,F,G,H and J 21:267 Arxulla adeninivorans 25:150 Aryl coumarins 24:799 derivatives of 24:740,741 ot-Aryl enamine substrates 18:327 ~-Aryl enamine substrates 18:333 Aryl ethano-bridge 11:295 Aryl methyl ketone 14:473 chiral acetal of 14:473 asymmetric cyanation of 14:473 cis-3-N-Aryl sufonamido borneol 4:661, 662 Aryl [3-C-glycosides 10:377 by condensation with tribenzyloxy benzene 10:377 by Lewis acid assisted condensation of aryl ether 10:375 1-Aryl-2-methyl cyclohexane 8:9 1-Aryl-2-methyl cyclopentane 8:9 2-Aryl-3-methyl-4-benzyltetrahydrofurans 17:331 Arylacetones 30:217 4-Arylamino 24:740,741 2-Arylbenzofuran 28:226 as anti-HIV flavonoids 28:226 2-Arylbenzofuran synthesis 30:223 from benzylalcohols 30:223 Aryl-C-glycosides 10:362,363; 11:139-142 by condensation 11:139-142 from ribofuranosyl chloride 10:362,363 via polyketides 11:139-142 synthesis of 11:139-142 4c~-Aryl-cis-decahydroisoquinolin 6formate 12:462 Arylcycloalkanes 8:6 4c~-Aryldecahydroisoquinolines 18:81 Aryldihydronaphthalenes 17:337 Arylethanals 30:214 acid treatment of 30:214
73 aldol condensation of 30:215 2-phenylnaphthalene from 30:214 1,2,9,10-tetrahydro- 1,9epoxydibenzo[a,e]cyclooctenes (Kagan's ether) from 30:214 Arylethanoid derivatives 30:213 reaction of 30:213 N-Arylethylhydroindoles 3:457 C-Arylglycals 10:344 by palladium catalyzed coupling 10:344 synthesis of 10:344 N-(Arylidene) benzyl amines 1:343 2-azaallyl anions from 1:343 isomerization of 1:343 Aryllactic acid 30:216 decomposition of 30:216 Arylnaphthalene lignans 26:194 Arylnaphthalenes 5:493;17:332 Arylnapthalene derivatives 24:762-775 synthesis of 24:761,766 3-Aryloxy-6,7-dihydroxycoumarin 30:220 Arylpropanoid 30:213 reaction of 30:213 Arylpyruvic acids 30:220 Aryltetrahydronaphthalene lignans 26:193 Aryltetralin lactone 30:570 Aryltetralin lactone-type lignan 30:586 Aryltetralin lignans 26:195,196 trans-Aryltetralinlactone type lignans 26:154 Aryltetralins 17:341,343;24:742 as anti-HIV agents 24:742 [3-Aryl-f3-methylacrylates 12:462 Arynes 3:418-421,422-454 as EBV inhibitor 30:592 generation of 3:418-421,422-454 nucleophilic additions of 3:418, 421-437 Asadanin I & II 17:369 Asarinin 26:226,231 (-)-Asarinin 26:260 (+)-Asarinin 26:267 8-Asarinin 5:753,754 Asarone 22:510,537
a-Asarone 26:470 ~-Asarone 22:510;26:470 Asarum maranthuym 22:513 for hysteria 22:513 Asatone 8:168 Asbcisic acid 2:164 Ascaridia galli 26:457,484 Ascaridole 20:13;26:431 Ascaris lumbricoides 23:837;26:425,429 Ascaris sp. 26:463,478 Ascaris suilla 26:443 Ascaris suum 26:443,450,477 Asci 22:247 Ascidia mentula 28:642 heneicosane- 1,21-diyl disulfate from 28:642 3,7,11,15tetramethylhexadecane1,19-diyl disulfate from 28:642 Ascidia nigra 10:241 ;23:242 Ascidiacyclamide 4:91-93;5:419,420; 10:242;25:879 Ascidian alkaloids 25:706 Ascidian metabolites 25:758 Ascidian tyrosine 23:241 Ascidians 23:233-283;25:707,709 aromatic alkaloids from 23:233- 283;25:707,709 Ascididemnin 23:274 Asclepiadaceae 5:751 ;18:649 Asclepias curassavica 5:249 Asclepias fruticosa 5:248,249 Asclepidaceae sp. 27:3 Ascobolus furfuraceus 5:279;21:209, 228,235 Ascochyta viciae 21:227;26:797 Ascocoryne sarcoides 29:266 Ascocorynin 29:266,296 biosynthesis of 29:296 inhibition of gram-positive bacteria by 29:266 synthesis of 29:299 Ascofuranone 26:797 Ascomycetes 9:202,203;22:460;25:129 Ascomycota sp. 22:246 Ascomycotina 9:202 L-Ascorbic acid 13:70
74 Ascorbic acid 21:503;25:236,349,930, 936;27:747 Ascorbic acid analogue 30:224 2-hydroxyfuran-2-one as 30:224 Ascosalipyrrolidinone A 28:148 against antibacterial activity of 28:148 against chloroquine-resistant Plasmodium falciparum 28:148 against Trypanosoma brucei 28:148 against Trypanosoma cruzi 28:148 Asebotoxin 20:17 Asernestioside A 25:195 Asernestioside B 25:195 Asernestioside C 25:195 Ashurbin 7:233 Asiasari radix 21:378 Asiasarum heterotropoides 21:378 Asiasarum hetrotropoides vat. madshuricum 24:228-232;26:212, 226 asarinin from 26:212,226 xanthoxylol from 26:212,226 Asiasarum sieboldii 21:378 Asiatic acid 25:541 Asiaticoside 15:213 Asimicin 9:391,392,396;26:441 Asimicin triacetate 9:391 ;17:262 Asimilobine 21:68;22:22;25:531 Asimina tiloba 9:391 Asinger condensation 12:127,129 Askendoside A 25:198 Askendoside B 25:194 Askendoside C 25:198 Askendoside D 25:194 Askendoside G 25:198 Aslcaligenes eutrophus 25:162 Aslchyta rabiei 26:1288 Asttonia macrophylla 13:383,422 Asltonia muelleriana 13:383,399,422 Asocainol 6:478 Aspalathus linearis 28:272 Asparaginase 25:719 Asparagine 26:1131 Asparagine acid 21:738 Asparagopsis sandfordiana 9:83-85 marine sterols from 9:83-85
Asparagus africanus 26:230,813 Asparagus cochinchinensis 17:116-117, 130.132
Asparagus curillus 7:427 Asparagus officinalis L. 21:636,662; 22:513;25:377;26:477
Asparagus plumosus 7:427 Asparagus racemosus 22:513 as anticonvulsant in epilepsy 22:513 for epilepsy 22:513 Asparagus sp. 17:130;25:37 Asparagusic acid 26:477 Asparenomycines 4:434 in carbapenems 4:434 Aspartate 21:10,14;30:836 c~2-macroglobulin inhibition by 30:836 Aspartate transaminase 21:655;25:477 L-Aspartic acid 6:263;12:160;13:63 4-acetoxy-[3-1actam from 12:160 Aspartic acid 21:214,738 Aspartic proteases 25:330,331,375; 29:568 as inactive zymogens 29:568 chymosin as 29:568 gastricsin as 29:568 haemoglobinases of Plasmodium falciparum as 29:569 immunodeficiency virus 1 (HIV1) protease as 29:569 in Alzheimer's disease 29:569 non-protein inhibitors of 29:570 overexpression of 29:569 pepsins as 29:568 [3-secretase as 29:569 N-Aspartyl-pseudodisaccharides 13:218 Asperdiol 10:18 activity against lymphocytic leukemia 8:15 growth inhibition of KB, PS and LE Cell lines 8:15 Asperentin 15:382,385-387 Asperger's syndrome (AS) 30:372,373, 384 form of autism 30:373 Aspergillimide A 26:491 Aspergillimides 26:491
75 Aspergillosis 2:422,425 Aspergillus aculeatus 23:343 Aspergillus acylase 1:678 Aspergillus alleaceus 20:792 Aspergillus arenarius 29:282,292 Aspergillus awamori 2:322,341,353 Aspergillus brevipus 12:400 Aspergillus caespitosus 19:480 Aspergillus campestris 29:269,281 Aspergillus candidus 29:267,268,270, 281 Aspergillus cellulosae 25:150 Aspergillus cladosporoides 26:228 Aspergillus clavatus 21:240 patulin from 21:240 Aspergillus deflectus 23:343 Aspergillus duricaulis 15:343,345 Aspergillus flavus 2:446;5:296;9:300; 15:386,245;18:711 ;26:228;27:225, 382;28:128,476 Aspergillus fumigatus 5:295-298,322, 326;7:65 ;9:300;12:400;18:469,807, 809;21:237 ;22:261 ;23:4,5 ;25:764; 26:228,458,673,1093,1128 helvolic acid from 21:237 Aspergillus melleus 15:383;21:211; 26:449 Aspergillus nidulans 5:295,296;21:188; 22:263,476;23:240;25:301,321 Aspergillus niger 21:217,240,396,599; 22:627;23:349;25:136,140-143,145, 148,149,152-155,157,158,165,166, 168,172,173,777;26:228,307,971,11 41,1144,1263,1268,1278,1280,1283, 1286,1287 ;27:382 ;28:476;29:548; 30:431,739 cz-L-rhamnosidase from 7:70 [3-glucosides from 7:51,52,55, 56,65-67 antibacterial activity against 30:739 antifungal activity against 30:739 cycloisomerase from 8:296 3-deoxy-2-keto-gluconate (KDG) aldolase from 30:431 glucoamylase from 7:62 isozyme I from 2:322,341
lactone from 8:300 metabolic function of 30:431 Aspergillus nomius 28:128 Aspergillus ochraceus 15:387;21:211; 25:139;27:382 ochratoxins from 15:387 Aspergillus oryzae 1:697,117;2:322, 341 ;5:295 ;6:551,552 ;13:304 ;21:238; 25:780;26:1007 Aspergillus parasiticus 22:266;27:382; 28:128 averufin by 11:194 Aspergillus sp. 2:323;5:276,278,294, 301,325,5:326,328,368,370;9:203, 300;21:196,204,233,239;22:57,248, 251 ;25:150,151,156,729;26:450,491 glucoamylase from 2:322 Aspergillus stellatus 10:439 (+)-asteltoxin from 10:439 Aspergillus taichungensis 29:269 Aspergillus tamarii 28:128 Aspergillus terreus 5:296,730;15:385; 19:168;21:212,233,240,239;22:627; 26:1281 ;30:220,431 patulin from 21:240 butyrolactone II from 30:220 Aspergillus versicolor 18:807,809 Aspergillus wentii 7:56,64;9:300; 28:454,465 Asperline 15:350,351;19:463 Asperula sp. 26:631 Asperuloside 7:439,455,469,470,479, 480;16:298;26:666 Asperulosidic acid 26:666 Asperulosidol 7:467,468 Asphaenogaster rudis 5:226,243-245 Aspiculamycin 4:242;26:493 Aspicularis tetraptera 26:493 Aspidosperma 19:114-115 Aspidosperma cyclindocarpon 19:112 Aspidosperma indole alkaloids 13:70,93 Aspidosperma marogravianum 1:124 Aspidosperma oblongum 1:124,125 Aspidosperma olivaceum 26:144
Aspidosperma quebrachoblanco
Schlecht 29:362 Aspidospermatan-type alkaloids 1:31, 32;5:71,86,87,135 Aspidospermatidine 1:40
76
Aspidospermidine 13:93;14:632-636; 26:140 (-)-Aspidospermidine 19:143 Aspidospermidine N- 14,15-methyl14,15-oxido 5:126 Aspidospermidose fi: 165-167 Aspidospermine alkaloid 18:338 Aspirin 30:192,195,594 AA-induced platelet aggregation inhibitor 30:594 as cyclooxygenase enzyme (COX) inhibitor 30:192,594 platelet aggregation role of 30:594 structure-activity relationships of 30:195 Aspochalasans 13:108,131,134 Aspochalasin B 13:142,143 Aspochalasin C 13:108,131,134 Aspochalasins 15:355 Aspterric acid 5:729,730,732,733; 21:232 Aspyrone 21:211;26:449 Assay 25:373;30:833,835 absorbance in 30:835 chromophoric oligopeptides in 30:835 chromophoric procedure in 30:835 for systemin activity 25:373 of EFE 30:835 of isozymers 30:833 ofLumbricus rubellus 30:833 scattering intensity in 30:835 Assay method 25:100 for hepatoprotective effects 25:100 Astaxanthin 6:153;20:577,578,588, 607;21:298,299,304,305;30:518,520, 533,538,543 course of formation of 30:543 radicals cations of 30:538 (3S,3'S)-Astaxanthin 6:158;7:361,362 (3R,3R)-Astaxanthin 7:321,361,362 (+)-Asteltoxin 10:439-442 absolute stereochemistry of 10:439,440 Claisen rearrangement by 10:439-442
from Aspergillus stellatus 10:439 synthesis of 10:439-442 Asteltoxin 16:670 from Aspergillus stellatus 16:670 Aster batangensis 21:673 asterbatanoside F from 21:673 Aster saponin A 15:209 Aster saponin H 15:210,211 Aster spathulifolius 25:251 Aster tataricus 24:339 Asteraceae 21:97;22:396;25:235,249, 250,252,944 ;30:704 as medicinal plants 30:704 in folk medicine 30:704 Asteremyces cruciatus 25:828 Asteria pectinifera 7:307 Asteriarubin 6:162;30:533 from Asterias rubens 6:161 Asterias amurensis 7:286-298,303; 15:44 Asterias amurensis vesicolor 7:287 asterosaponin-i from 7:287 thornasteroside A from 7:287 versicosides (A-C) from 7:287 Asterias forbesi 7:288;15:58,69;28:718 Asterias rubens 6:151,152,156,161; 7:288,294,304,306;15:48 Asterias vulgaris 7:288,291,304;15:59; 28:718 Asterina pectinifera 7:289;15:44,48,55; 25:698 Asterinic acid 6:161 Asterogenol (20R-5c~-pregn-9(11)-ene3~,6c~,20-triol) 7:288,291 Asteroidea 7:265,285-307;15:43-45 Asterone 15:45 Asterone (3[3,6~-dihydroxy- 5ot-pregn9(11)-en-20-one) 7:290,291 (+)-Asterosaponin 7:285,288,290,291, 294,7:303,304 Asterosaponin 1 (forbeside C) 7:287, 288,293 Asterosaponin A and B 7:286,303 from Asterias amurensis 7:286,303
77 Asterosaponin D1-D3 7:299,302,303 biosynthesis of 7:299,302,303 from Distolasterias nipon 7:299 Asterosaponin P~ 7:297,300 from Oreaster reticulatus 7:297,300 Asterosaponins 15:45-58 Asterosides A-D 7:287,293 Asthma 30:70,225 treatment of 30:225 Astichoposide C 7:273,281,282 from Astichopus multifidus 7:273 Astichopus multifidus 7:272,273,281 astichoposide C from 7:273 Astilbe chinensis 27:395 Astilbejaponica 27:395 Astilbe revularis var. rivularis 27:395 Astilbe thunbergii 27:395 Astilbin 27:395 structure of 27:396,397 Astins 24:339 Astiraversianins 25:179 Astrachyside A 25:194 Astracicerans 256 27:498 Astragali radix 27:443,445,507,513 activity of 27:513 Astragali semen 27:478 Astragalin (kaemp ferol-3- O- [3-Dglucoside) (flavonol glycoside) 29:578 effects on ACE 29:578 Astragalloside 25:104 Astragallus genus 25:188,190 Astragallus sp. 25:180,183,186,187, 190,219;27:253 Astragaloside 25:179 Astragaloside I 25:193,224,227 Astragaloside II 25:193,220,221,223, 224,227 Astragaloside III 25:194 Astragaloside IV 25:193,220,221,224, 226,227 Astragaloside V 25:195 Astragaloside VI 25:194,224,227 Astragaloside VII 25:194 Astragaloside VIII 25:95,115,116,118, 120,203,222 Astragaluquinone 27:505
Astragalus adsurgens 25:184;27:478, 450
Astragalus aitosensis M.B 27:449,450, 511
Astragalus alexandrinus 25:184,189,
192,193,214,224 ;27:454,476,477, 500,505 Astragalus alopecuros 25:184,201; 27:449,452 Astragalus amarus 25:194,195 Astragalus angustifolius 27:466 Astragalus babatagi 25:184 Astragalus basineri Trautv. 25:184,194 Astragalus bethlehemiticus 25:188,189 Astragalus bisulcatus 27:516,527,528 Astragalus boeticus 25:192 Astragalus brachycentrus 25:184,192, 193,197;27:454;30:405,411 antiviral activity of 30:405 Astragalus bungeanus Boiss 27:453 Astragalus canadensis L. 27:444,522 Astragalus caryocarpus 27:444 Astragalus centralpinus 27:505 Astragalus cephalotes 25:184,197; 27:454,455 Astragalus collinus 27:522 Astragalus coluteocarpus 25:184,192 Astragalus complanatus 25:93,184, 203,204;27:445,453,477,478,481; 27:453 Astragalus convallarius 27:525 Astragalus crotolariae 27:528 Astragalus da~yanthus Pall. 27:451 Astragalus dissectus 25:184,192; 27:440,449 Astragalus echianaeformis 27:514; 30:405,411 antiviral activity of 30:405 tragacanthin polysaccharide (PS) from 30:411 Astragalus edulis 27:444 Astragalus emoryanus 12:313 (-)-swainsonine from 12:313 Astragalus ephemerotum 25:184;27:449 Astragalus ernestii 25:184,195 Astragalus exilis L. 25:184 Astragalus falcatus 25:196;27:511 Astragalus flexuosus 27:522 Astragalus floccosifolius 27:504
78
Astragalus furcouga 25:472 Astragalus galegiformis L. 25:184,196; 27:450,470
Astragalus genus 27:470,523 Astragalus glycyphyllos L. 25:184,203; 27:444,453,466,477
Astragalus gummifer 25:188;27:444, 499,511
Astragalus hamosus L. 25:184 Astragalus illiensis L. 25:184,195 Astragalus kahiricus 25:189 Astragalus kuhitangi 25:184,192,194; 27:455
Astragalus kulabensis 25:184;27:449 Astragalus kurdicus 27:511 Astragalus L. genus 27:443 biological activity of 27:443
Astragalus lasioglottis 27:505 Astragalus lentiginosus 7:11,486;
27:251,515,524,517 (-)-swainsonine from 12:313 Astragalus lusitanicus 27:524 Astragalus melanophrurius Boiss 25:184,192,25:193,194,197 ;27:455, 482 Astragalus membranaceus 27:482 antiviral activity of 27:482 Astragalus membranaceus Bunge 22:97;24:145;25:184,192,193,194, 195,200,205,219,220,221 ;27:443, 445,450,467,468,505,511,446,468, 470,481-483,500,506,508,513,665 Astragalus miser 27:525 Astragalus miser var. oblongifolius 27:519 Astragalus miser var. serotinus 27:521 Astragalus mollissimus Torr. 27:444 Astragalus mongholicus Bunge 25:184, 192,193,194,202,219;27:448,454, 467,503,504,508,511 Astragalus oleifolius DC 25:185,199; 27:448 Astragalus onobrychis 27:453,466,504, 480 Astragalus orbiculatus 25:185,202; 27:452,515 1-hydroxyindolizidine from 27:515
1,2-dihydroxyindolizidine from 27:515 Astragalus pamirensis 25:185,192,197, 200,202,203 ;27:449 Astragalus pattersonii 27:528 Astragalus pectinatus 27:528 Astragalus penegrinus Vohl 25:185, 195,216,225 Astragalus polycanthus 27:517 Astragalus praelongus 27:516 Astragalus pterocarpus 25:185,192, 193;27:525 Astragalus pterocephalus 27:449 Astragalus pycnanthus 25:185,193, 198;27:450 Astragalus quisqualis Bunge 25:185; 27:450,504 Astragalus racemosus 27:528 Astragalus root 27:445 medicinal use of 27:445 Astragalus severtzovii 27:478 Astragalus shikokianus 27:453 Astragalus siculus 27:482 Astragalus sieberi 27:470 Astragalus sieversianus 27:449,478, 480,481,483 Astragalus sinicus 27:453,511 Astragalus spinosus 21:664;27:468,483 astragaloside II from 21:664 Astragalus spp. 7:23;25:179;27:253, 454-465,474,478,483,498,500,503, 511,519,520,521,523,745 activity of 27:483 biological activity of 27:443 of Leguminosae 27:519 of saikosaponin 27:671 Astragalus subrobustus 27:504 Astragalus tashkendicus 27:454 Astragalus tibetanus 27:517 Astragalus toanus 27:516 Astragalus tomentosus 27:451,473 Astragalus tragacantha Habl. 27:448, 454 Astragalus trigonus DC 27:448,500,505 Astragalus trojanus Stev. 27:453,454, 479 Astragalus wootoni 27:516 Astragersianin VII 25:193 Astrailienin A 25:195
79 Astramembranin I 25:193,220 Astraverrucln I 25:194 Astraverrucln II 25:194 Astraverrucln III 25:194 Astraverrucln IV 25:195 Astraverrucm V 25:195 Astraverrucln VI 25:195 Astraverslanm I 25:193 Astraverslanln II 25:193,224 Astraverslanln IV 25:193 Astraverslanm IX 25:194 Astraverslanm V 25:193 Astraverslanm VI 25:193,224 Astraverslanm X 25:192,224,227 Astraverslanm XI 25:194,226 Astraverslanln XII 25:195 Astraverslanln XIII 25:195 Astraverslanln XIV 25:193,194,224 Astringent 5:751,754 Astringent agent 23:642 of teucrium sp. 23:591 Astrocytes 30:367 Astrojanoside A 25:203 Astropecten aurantiacus 15:104;15:61 Astropecten indicus 5:214;7:299 Astropecten latespinosus 7:288;15:48 Astropecten polyacanthus 7:306;18:725 Astropecten scoparilis 15:68 Asuka-mABA 21:401 Asukamycin 11:189;23:92 Asukamyene 21:398 Asymmetric 11:367 alkylation 11:367 base (LDA) mediated 10:408,409 catalytic epoxidation 11:431, 432 catalytic osmylation 11:431,432 cycloaddition 11:358 dihydroxylation of 11:423,424 diastereoselective 14:491-499 enantioselective 10:412 in basic media 4:389-391 intramolecular 16:125;19:486 of (-)-arctigenin 24:749 of (S)-c~-terpinylamine 11:283 of 1,5-acetyl- 1-thiohex-2enopyranosides 10:342 of 1-benzyl-2,6-dicyanopiperidine 6:433
of 1-phenyl- 1-methyl 6,7 seleno1-ethyllithium 8:6,7 of 2-acetoxy-5,6-dihydro-2Hpyrans 10:342 of acetals 1:613-616 of benzyllithium 8:6 of carbanion 8:176 of carvone 10:408,409 ofchiral acetals 12:489-493 of cyanohydrin 8:16 of cyanohydrin ethers 8:177-179, 183 of dianion 11:284,285 of dimethyl malonate 8:185,186 of dioxolane enolates 1:644 of (-)-dimethyl matairesinol 24:749 of (-)-enterolactone 24:749 of (-)-hinokinin 24:749 of (-)-kusunokinin 24:749 of (-)-yatein 24:749 of FAMSO 6:313 of fluoromalonate 13:82 of methylmalonate 13:79 of MT-sulfone 6:334 of N-nitrosopyrrolidine 6:439,441 of silver cyanides 12:113 of sulfur stabilized carbanion 8:16 of trans-2,5-bis (methoxymethoxymethyl) pyrrolidine 10:412 of w-haloalkylphenylthioacetate 8:176 of et-methyl-phenylacetic acid 10:412 of c~-phenyl-?,-lactone 10:410, 411 of ~-ketoester 8:181,191 palladium-mediated 16:422 regioselective 10:342 stereoselective 10:342,410,411; 11:284,285 synthesis of 3:166,167 TiCI4 catalysed 1:615 trans-stilbene 11:423,424 via sequential dianion generation
80
16:371 with 1-TMS-2-pentyne 11:284, 285 with 2,5-dibromo-2-methyl pentane 8:6,7 with 3-butynyl p-toluene sulphonate 14:559 with allylic halide 8:178 with benzyloxymethyl chloride 6:561 with di-t-butyl dicarbonate 14:559 with House procedure 10:308, 309 with indole-protected tryptophyl bromide 11:283 with organometallic reagents 1:613-616 Asymmetric [3+2] dipolar cycloaddition 13:500 Asymmetric 1,3-dipolar cycloaddition 1:371-375 Asymmetric additions 4:332 to prochiral carbonyl groups 4:332 to prochiral naphthalene rings 4:332 Asymmetric aldol condensation 12:162; 13:63 Asymmetric aldol methodology 21:438 Asymmetric alkylation 10:411 of methylmalonic acid 10:411 of (-)-phenylmenthyl ester 10:411 Asymmetric allylboration 8:477,478 Asymmetric aza-annulation reaction 18:378,379 Asymmetric bromolactonization 4:338, 339 with acetals from tartaric amides 4:338,339 with N-bromoacetamide 4:338, 339 with chiral acetals 4:338,339 with unsaturated (S)-proline amides 4:336,337 Asymmetric carbocyclization 6:62,63 in (-)-2R,6S,8S,9S)-2,8-dibromo-
9- hydroxy-ot-chamigrene synthesis 6:62,63 Asymmetric catalysts 17:323 hydrogenation of 17:323 synthesis of 17:479 Asymmetric cyclization 10:611, 631-633;14:506,507 biomimetic 14:506,507 of chiral acetal 14:506,507 Asymmetric cyclopropanation 14:488 with methyl carbenoid 14:488 Asymmetric Diels-Alder reaction 8:139-157 at chiral auxiliaries 4:607 in prostaglandin synthesis 4:607 in tetramycin synthesis 4:607 using chiral boron reagent 4:609 in [3-santalene synthesis 4:607 Asymmetric Diels-Alder technology 13:602 Asymmetric dihyroxylation 11:60; 19:269-270,274,278,284 Asymmetric dimethylation 10:412-415 Asymmetric epoxidation 4:172-174; 10:561;12:323 of (+)-N-benzyloxycarbonyl-3hydroxy-4-of allylic alcohols 4:172-174;10:561 ;12;323 ofpentenylamine 12:281 of swainsonine 10:561 Asymmetric esterification 9:25 Asymmetric hydration 13:71 ofalkenes 13:71 Asymmetric hydroboration 8:473,474, 478;13:71,72 Asymmetric hydrogenation 12:162; 16:411;24:749 BINAP-Ru-catalyzed 4:439 of[3-keto esters 4:439 Asymmetric hydrolysis 1:684,685 by esterases 1:684,685 by lipases 1:684,685 of N-acetyl (x-amino acids 1:678,679 Asymmetric hydrosilylation 13:72 intramolecular 13:72 Asymmetric hydroxylation 9:572 of pentadienols 9:572
81 Asymmetric induction 10:412; 12:153, 156;14:471,507,508,524,553 1,2-Asymmetric induction 11:231-238 1,4-Asymmetric induction 12:156 1,5-Asymmetric induction 14:499 1,3-Asymmetric induction 14:529,552 1,6-Asymmetric induction 14:530 1,4-Asymmetric induction 4:203,495 Cram's cyclic model of 4:203, 495 in (-)-piperitone 6:15 in aza-annulation reaction 18:373-386 in dienolate addition 3:47 in diyl trapping 3:20 in Ireland-Claisen rearrangement 3:237 reversion using sulfoxides 4:511 self-immolative 3:237 with chiral auxiliaries 4:499-517 Asymmetric ketoester cyclization 4:328-330 Asymmetric metallation 14:511 of chiral arylaldehyde acetal chromium tricarbonyl complexes 14:511 Asymmetric Michael addition 4:501, 502 in estrone synthesis 4:501,502 Asymmetric osmylation 19:269 Asymmetric oxidation 14:517,518 ofprochiral sulfides 14:517,518 of sulfide 4:489 sulfoxides from 14:517,518 with chiral sulfamyloxaziridines 4:489 with chiral titanium complexes 4:489 Asymmetric quaternization 10:426-428 by Claisen rearrangement 10:426-428 by consecutive alkylation 10:405,406 of aldohexofuranose derivatives 10:428-432 of m-carbon of y-lactones 10:405 Asymmetric reduction 10:410 by Baker's yeast 10:410
of acetoacetic acid ethyl ether 10:410 of acetylenic ketone 11:424 of acyclic ~-hydroxy ketones 14:183,184 of~-keto esters 14:533,534 with Baker's yeast 1:689 with Ipc2BH 8:476 Asymmetric synthesis 24:744-754,761, 766,767,772,773,775,777,780,781 by diastereofacial selection 13:62-70 by enantiofacial selection 13:70-73 by enantiotopic discrimination 13:60-62 of (+)-azaisopicrostegnane 24:775,777 of conidendrin 24:772,773 of 2,3- dibenzylbutyrolactones 24:744-754 of(+)-gomisin A 24:775-777 of (+)-isolarresinal 24:767 of (+)-isoschizandrin 24:775,777 of (-)-isoschizandrin 24:780,781 of (+)-paulownin 24:761,766 of (-)-podophyllotoxin 24:767, 775 of (+)-schizandrin 24:775-777 of (-)-schizandrin 24:780,781 of paraherquamide A 28:331,367 of carbaoxirose/carbaoxetoses 29:490 of (-)-ajmalicine 14:563,564 of (-)-sibirine 14:539-544 of (+)-(S,S)-solenopsin A 6:431, 432 of (+)-castanospermine 12:346 of(+)-elaeokanine A 12:351,352 of (+)-elaeokanine C 12:351,352 of (R)-muscone 14:490 of (R/S)- 1,6-dioxaspiro [4.5] decane 14:523,524 of (R/S)- 1,7-dioxaspiro [5.5]undecane 14:521-526 of[m, n, 1] propellanes 14:490 of 2-deoxy-D-arabino-hexose 14:176,177 of 3-deoxy-D-ribo-hexose
82
14:176 of 4-acetoxy-3-[ l'-(tertbutyldimethyl-silyloxy) ethyl]azetidinone 4:448 of 4-deoxy-D-lyxo-hexopyranose 14:176 of 5,1-1inked naphthylisoquinoline alkaloids 20:420-438 of 5,8-1inked naphthylisoquinoline alkaloids 20:442-451 of 7,1-1inked naphthylisoquinoline alkaloids 20:438-441 of anthracycline antibiotic 14:492,493 of azetidinone 4:448 of buphanisine 4:14,15 of chiral alkaloids 10:671-689 of chiral building blocks 14:551-581 ofchiral isoquinolines 10:671 of chiral piperidines 10:671 of crinine 4:14,15 of desoxydaunomycinone 14:23 of indolizidine alkaloids 6:442, 443 of monomorine I 6:449,450 of pyrrolidine alkaloids 6:442, 443 ofpyrrolizidine alkaloids 6:442, 443 of R,S-4-hydroxycyclopentenones 6:315 of solamin 18:202-206 of talaromycin A and B 14:531-539 propane-l,3-diols by 13:53-105 via chiral organoboranes 8:465-478 with chiral sulfur reagents 10:671-689 Asymmetric transformation 13:77 crystallization-induced 13:77 of malonic acid derivative 13:88 Asymmetrization 11:241,242 of cy-symmetric ketones 11:241, 242 AT2433-AI 12:366,368 from Actinomadura melliaura 12:366,368
AT2433-A2 12:366,368 from Actinomadura melliaura 12:366,368 AT2433-BI 12:366,368 from Actinomadura melliaura 12:366,368 AT2433-B2 12:366,368 from Actinomadura melliaura 12:366,368 Atalantia ceylanica 13:348,349,356 1,5-dihydroxy-3-methoxy- 10methylacridin-9-one from 13:348,350 11-hydroxynoracronycine from 13:348,349,356 11-O-methylatalphilidine from 13:348,349 N-methylatalphyllinine from 13:348,349 Atalantia monophylla 13:348-350 atalphyllidine from 13:348,349 atalphylline from 13:350 atalphyllinine from 13:349 N-methylatalphylline from 13:350 Atalfoline 13:350 from Citrus buxifolia 13:350 Atalphyllidine 13:348 from Atalantia monophylla 13:348 Atalphylline 13:350 from Atalantia monophylla 13:350 Atalphyllinine 13:348,349 from Atalantia monophylla 13:348,349 Athanasin 16:666 from Athanasia L. 16:666 Atherosclerosis 11:335;12:399;22:310; 23:470,766;25:934 ;30:224 development of 23:766 of S-allyl cysteine (SAC) 23:470 role of free radicals in 30:224 Ent-Atis-16-ene-3,14-dione 9:68,269, 276,277,279,290 Atisane 25:241 Atisane diterpenoids 9:267-281 EntAtisane ent- 16c~,17-dihydroxyatisan-3one 29:100
83 activity in mam-2 assay system 29:100 Ent-Atisanes 9:267-283 Atisense RNA 13:257-261 gene expression by 13:257-261 natural regulation of 13:257-261 Atisine 3:435;26:868 synthesis of 3:435 Atisirene 10:180 synthesis of 10:180 Atmospheric pressure chemical ionization 21:555 Atomic orbital coefficients 4:586 in Diels-Alder reactions 4:586 Atopic dermatitis 30:70 Atovaquone 26:840 H+,K+-ATPase 21:690,701,702,717,719 inhibitory effect on 21:701,719 ATPase activity 21:137 Atractylis gummifera 20:8 Atractylodesjaponica 29:88 Atractylodes lancea 24:877,878,883, 29:694 Atractylon 29:88 activity in TPA, skin-1 assay systems 29:88 Atractyloside 20:8 Atrazine 25:669 Atrial natriuretic factor (ANF) 25:519, 540,547 Atrial natriuretic peptide 27:870 Atromentin 29:271,296 against Bacillus subtilis 29:272 antibacterial activity of 29:271 as anticoagulant principle 29:271 biosynthesis of 29:296 Atropa belladonna L. 20:135;22:721, 734,742,8 Atropa genus 17:395 Atropa sp. 21:104,488 Atropine 21:488;22:735 Atropine (DL-hyoscyamine) 22:19 Atropisostreptovaricin C 23:65 Atropisostreptovaricin Fc 23:65 2-ATT (2-acetylthiazole) 11:443,444 Atta cepholotes 22:66 2,5-dimethyl-3-ethyl-pyrazines of 5:222
Atta sexdens rubropilosa 5:222;26:186 2,5-dimethyl-3-ethyl-pyrazines of 5:222 Atta sexdens sexdens 5:222 2,5-dimethyl-3-ethyl-pyrazines of 5:222 Atta texana 5:234,125 [3-Attantone 23:830 Attanuatoside C 7:295,296,300 Atta-ur-Rahman synthesis 14:850 of (+)-16-hydroxydihydrocleavamine 14:850 of (+)- 16-methoxycarbonyldihydrocleavamine 14:850 of (+)-coronaridine 14:850 of (+)-dihydrocatharanthine 14:850 of (+)isovincadifformine 14:850 of (+)-c~-dihydrocleavamine s 14:850 of (+)-[3-dihydrocleavamine s 14:850 of anhydrovinblastine 14:857 of vinblastine 14: 850-859 of vincristine 14:850-859 Attenuatodside 7:295 from Hacelia attenuata 7:295 Attenuatoside A-1 7:295-297,299,300 Attenuatoside A-II 7:295,296,300 Attenuatoside B-I 7:295,296,300 Attenuatoside B-II 7:295,296,300 Attenuatoside C 15:61 from Hacelia attenuata 15:61 Atuna racemosa 29:708 Aucubigenin 7:478 Aucubin 7:440,455,465,472,473,476, 478,479,480,481-483 ;29:84 activity in TPA assay system 29:84 6-epi-Aucubin 7:472,473 Auguidine 6:225,226,229 Augustilobine A&B 9:171 Aulacocarpin A 23:799 Aulacocarpin B 23:799 Aulacocarpines A & B 25:259 Aulacocarpinolide 23:799;25:259,266 Aulacophora femoralis 23:66
84
Aulacophora femoralis chinensis 18:771 Aurainvilleol 25:787 (+)-Auranthioclavine 16:438 synthesis of 16:438 Aurantiamide acetate 7:220 from Artemisia anomala 7:220 Aurantinin 5:601,603 Aurantinin A 5:601,604-607 Aurantinin B 5:601,603-606 Aurantoside A 25:763,793;26:1176, 1179 Aurantoside B 25:763;26:1176,1179 Aurantoside C 25:793 Aurantoside F 25:763 Aurantosides 25:757,763 Aurapten 20:497 from Limonia acidissima 20:497 AURELIA 23:30 Aureobasidin A 23:343 Aureobasidin A insitol 22:248 phosphyorylceramide 22:248 Aureobasidins 22:248 Aureobasidium pullulans 5:307,308, 314;21:396;22:248;23:343 Aureobasidium sp. 5:307 Aureol 5:430,431,437,438,444;9:31,32; 15:300,314 Aureolic acid antitumor antibiotics 3:173-206 Aureolic acid 3:173-175 Aureomycin 25:757 Aureothin 5:551 Auricularia auricula-judae 5:290,316, 318,319,733 Auricularia sp. 5:287,317,320 Aurilol 25:763 Auriside 25:757 Auriside A 25:762;27:789 Auriside B 25:762;27:789 Auristain 25:716 Aurones 7:192;22:420;26:744,801; 27:893 Ausantoside E 25:780 (-)-Austalide B 18:32 from Aspergillus ustus 18:32 Austalides A-F 18:32,37 Australine 7:13;10:567;22:183 amyloglucosidase inhibitor of
7:13;10:567 from Castanospermum australe 7:13;10:567 ~-glucosidase inhibition by 7:11 glucosidases I,II inhibition by 7:13 oligosaccharide chain inhibitor 10:567 Austrobailignan-1 26:193 Austrocedru chilensis 19:405 Austrovenus stutchburgi 25:864;28:656 brevetoxin BI from 28:656 Autism 30:368,371,374,375 as neurodevelopmental disorder 30:371 brain parts affected by 30:375 etiology of 30:368 genetic component to 30:375 impairments in reciprocal social interaction in 30:368 in dizygotic (DZ) twins 30:371 in monozygotic (MZ) 30:371 incidence of 30:374 pathogenesis of 30:368 prevalence of 30:374 restricted pattern in 30:368 role ofamygdala in 30:375 role of serotonin (5-HT) 30:368 stereotyped pattern in 30:368 symptoms of 30:371 with multiple etiologies 30:371 Autistic brain 30:376 neuropathological studies of 30:376 Autistic children 30:375,377 cerebellar hypoplasia in 30:375 signal reception in 30:377 Autistic disorder 30:372 diagnostic criteria for 30:372 Autistic features 30:374 in alcohol consumption 30:374 in congenital cytomegalovirus 30:374 in fragile X syndrome 30:374 in hypothyroidism 30:374 in matemal thalidomide 30:374 in phenylketonuria 30:374
85 in rubella infections 30:374 in tuberous sclerosis 30:374 Autistic individuals 30:375 Autistic spectrum disorders 30:374 neurochemical pathway of 30:374 Autoimmunodeficiency syndrome 18:908 Automated synthesis 13:257-294 of oligonucleotides 13:257-294 of oligodeoxyribonucleotides 4:280 reaction cycle 4:281 Automatic DNA synthesizer 4:304 Autooxidation 14:335,336 of 1-methylazulene 14:335,336 ofbenzylic positions 16:571 of guaiazulene 14:316-319 ofphenylhydrazine 9:581 Autoradiographic imaging 30:377 serotonergic innervations in 30:377 Autotoxic effects 28:537 of NO on tumor cells 28:537 Auxarthron unberium 25:794 Auxiliary enolate 21:231 Auxins 17:424;25:367,379,652,656, 657;26:581 effect on root culture growth 17:424 indoleacetic acid as 7:90 naphthalene acetic acid as 7:90 Avarol 5:430,431,438,439;9:30,31; 15:238,252;21:252;25:697;29:111 activity in CRG bioassay system 29:111 activity in TPA bioassay system 29:111 Avarol monoacetate 15:300 Avarone 5:430,431,434,438,439; 15:301,314;21:252;25:697;29:111 activity in CRG bioassay system 29:111 activity in TPA bioassay system 29:111 2-AVD treatment 25:462 Avena fatua L. 27:215-217,218 allelopathic interaction of 27:215
Avena sativa 9:220;23:341;27:216-218 allelopathic interaction of 27:216 Avena strigosa L. 27:215 allelopathic interaction of 27:214-218 Avenacin A-1 25:304-306,314 Avenacinase 25:304-306,308 Avenaciolide 3:259,260;19:485 Avenalumin I 23:341,348 Avencins A1,Az,BI,B2 7:136,137 Avenestergenins A1,Az,BI,B2 7:136,137 Average mass 2:26 Avermectin 12:13,709;26:425,426,442, 453,494 biological activity of 12:709 structure-activity relationship of 12:8 Avermectin A 12:3 Avermectin A~a 12:12,13,15 Dainshefsky synthesis of 12:12,13,15 from D-robosa 12:12,13 from Streptymyces avermitilis 12:6 Avermectin B 12:3 Avermectin B~ 12:9 insecticidal activity of 12:9 Avermectin B~ 1:463-465 synthesis of 1:463-465 Averrhoa carambola 22:359;23:785 Avian hemoglobin 5:849 alkaline denaturation 5:841 allosteric regulator binding sites 5:849 amino acid composition 5:841 carbon dioxide transport 5:853 electrophoretic mobilities 5:839841 heme binding sites 5:869 heterogeneity in 5:856 inositol pentaphosphates in 5:857 oxygen affinity 5:856 oxygen uptake 5:853 physiology 5:854-859 primary structure 5:844-850 structure of 5:835-850 Avicennia alba 7:176,181,182,189,195
86 Avicennia germinas 7:175 Avicennia marina 7:176,180,183,184, 194,195 Avicennia officinalis 7:176,181,182, 189,195 Avicennia resinifera 7:193 Avicennia sp. 7:176 Avicennia tomentosa 7:189 Avicenol 4:372,373 Avicine 14:770;27:156 fagaronine 27:156 sanguilutine 27:156-158,161,162 terihanine 27:156 Avicularia 17:193 Avicularin 26:359 Avidin 18:919 Avidinphosphatase assay 4:284 125I-AVR9 25:400 Avrainvillea longicaulis 25:787 Awamycin 21:420,435;23:62,86 configuration of 23:86 E configuration in 23:62 Z configuration in 23:62 Axamide-1 6:5 fromAxinella cannabina 6:5 synthesis of 6:5,6 Axamide-3 21:330,366 Axane skeleton 25:848,850 Axenomycin 19:555 Axial 2-1ithiotetrahydropyrans 10:380 by reduction with lithium di-tertbutylbiphenylide 10:380 from 2-(phenylthio)tetrahydropyrans 10:380 Axial C-glycopyranosides 10:365,366, 382 Axillarin 7:26 Axillaroside 7:26 Axinella 25:847 Axinella cannabina 6:5;21:329,349,364; 25:848,852,85328:658 axamide-1 from 6:5 axisothiocyanates from 28:658 axisonitrile-1 from 6:5 axisothiocyanate 2 from 28:658 axisothiocyanate 3 from 28:658 axisothiocyanate 4 from 28:658 sesquiterpenoid from 28:658 Axinella carteri 21:254,270;25:714
Axinella sp. 21:270;25:705 Axinella verrucosa 21:270 Axinella weltneri 25:700 Axinellamine B 25:778,779 Axinellamines 25:778 Axinellida 25:847;26:464 Axinellida order 28:658 Axinyssa 25:694,847,848,859 Axinyssa aplysinoides 21:354;25:852, 853,858 Axinyssa fenestratus 25:852;26:463, 464;28:662
10-isothiocyanato-4,6-
amorphadiene from 28:662 4-isothiocyanato-9-amorphene from 28:662
10-isothiocyanato-5-amorphen-4-
ol from 28:662 Axinyssa. sp. 21:351,353,355,356,359, 364,366,367 ;28:661 Axisonitrile 26:810 Axisonitrile- 1 6:5;21:364 fromAxinella cannabina 6:5 synthesis of 6:5,6 Axisonitrile-2 21:349 Axisonitrile-3 21:330,351,356,359,365; 26:812 3-Axisothiocyanate 25:848 4-Axisothiocyanate 25:852 1-Axisothiocyanate 25:852 (+)-Axisothiocyanate-2 25:853 Axisothiocyanate-3 21:330,351,359 Axon terminals 21:7,9,16 Ayamenin A 22:473 Ayamenin B 22:473 Ayani 7:226,411-413 Ayanin 23:798 Ayapin 23:359 Ayobangira 21:595 Aza spirocycle 10:215,216 Aza-[2,3]-Wittig rearrangement 19:22, 45,50 2-Azaallyl anions 1:344-347 by deprotonation of imines 1:344-347 by C-Si of C-Sn bond cleavages 1:344-351,353 from imines 1:344-347 from N-lithioimidazolidines
87 1:344,349-351 from N-metalloaziridines 1:344,348,349 generation of 1:348,350 geometry of 1:348,350 Azaallylic anions 4:547 with aryl halides 4:547 Aza-annulation 18:315-386 of enamine related substrate 18:315-386 Aza-annulation reaction 18:373-386 asymmetric induction in 18:373-386 8-Azabicyclo [3.2.1] octan-3-one 14:573,574 asymmetric cleavage of 14:573,574 N-protected 14:573,574 9-Azabicyclo [3.3.1 ] nonan-3-one 14:571-574 trimethylsilyl enolate 14:572,573 with chiral lithium amide 14:571-574 Azabicyclo [3.3.1] nonane 11:28021-Azabicyclo [4.3.0] nonane (octahydroindolizine) 11:229 Azabicyclo ketone system 14:571-574 asymmetric cleavage of 14:571-574 cis-c~,c~'-disubstituted piperdine by 14:571-574 pyrrolidines by 14:571-574 Azabicyclo[2.2.1] heptane 19:667endo-7-Azabicyclo[2.2.1 ] heptanol 19:71 Azabicyclo[2.2.1] heptanone 19:71 3-Azacephalosporine 12:137 Aza-Claisen rearrangement 16:467 Aza-Cope reaction 16:481 Aza-Cope rearrangement 1:68,69 Mannich directed 1:68,69 Aza-Cope-Mannich strategy 16:435 Aza-Diels-Alder approaches 16:456 Azadiene Diels-Alder 3:311 1-Azadiene Diels-Alder cycloadditions 16:457 2-Azadienes 4:7,10-14,17 metalloenamines from 4:7, 10-14,17
Azadirachta indica 9:293-311;13:644; 15:384 ;22:95 ;26:466,814 ;28:388, 395,389,401,404,414,573,581 azadirachtin from 26:466 Azadirachta indica oil 28:388,395 against bee mites 28:387 against blood sucking ticks 28:395 Azadirachtin 7:397;9:93,94,96, 103-105,297 ;23:488 ;30:696 Azadirachtol 9:308 Azadirol 9:297,298,300,306,308 Azadirone 9:302,304-306 Azafluoranthenes 1:167,169 Azafria 30:528,529 structure of 30:529 Azafulvene 9:596 Azafulvene bilane 9:593,595 Azahexatriene 3:395 thermal cyclization of 3:39522-Azahexatriene 3:395 thermal cyclization of 3:395 Azalides 13:161,162 Azaphilones 23:343;26:450 6-Azaspiro (4,5) decane 25:871 Azasteroids 4:540 Azasugars 14:179 Azatidine acetates 23:195 isomerization of 23:195 Aza-Wittig reaction 1:168,169 Azepine ester 19:99 Azepine-type bromopyrrole 25:799 3-Azetidinol 18:677 from Chara globularis 18:677 Azetidinone 13:87;4:437,441,448,450, 452-454,457,458,461-466;8:264 1-Azetidinone acetic acid 12:138 Azetidione derivatives 13:500 Mori's synthesis of 13:500 Azetidone 5:412-414 Azidation reaction 19:311 asymmetric 19:311 Azides 3:49 dipolar cycloaddition 3:49 thermolytic cyclization of 6:429 1-Azido- 1,2,3-trideoxy-D-arabino-oct-4ulose 12:350 8-Azido- 1-p-menthene 11:288 reduction of 11:288
88
6-Azido- 2,4-di-O-benzyl-3,6-di-deoxyot-D-ribo-hexopyranosyl chloride 14:145 2-Azido-2-deoxy derivative 6:388 of D-glucose 6:388 ofmuramic acid 6:387,388, 402,403 2-Azido-2-deoxy-D-glucose derivative 6:388 3-Azido-3-deoxy- 1,2-O-isopropylidene~x-D-glucofuranose 12:325 Azido-4-deoxy-D-mannose 12:316 5-Azido-5-deacetamido-Neu 30:426 6-Azido-6-deoxy-D-arabino hexulose 10:536 Azido-6-deoxy-L-xylo-hexulose 10:536 1-Azido-abscisic acid 27:330,331 2-Azidobenzaldehyde 13:448 Azidobutenolides 13:448 a-Azidocinnamates 1:165 2-Azido-D-arabino-hexofuranoses 6:369 5-deoxy-5-(phenylphosphinyl) Lfucosamine from 6:369 from D-ribo-hexafuronose 6:363 Azidodeoxy-myo-inositol 18:411 Azido-ene reaction 16:473 Azidonitration 1:420,421 ;10:465 Azido-olefin cyclization 13:447,448 4-Azidosampangine 23:6 Azidothymizine 23:97 Aziridine 10:138,139 from (S)-phenylglycinol 10:138,139 azomethine ylides from 1:328-331 fused 1:189,197 nucleophilic opening 1:201,202 photochemical opening 1:328 synthesis of 1:189,197 thermal opening in 1:328 Azithromycin 13:161,162,183 Azobisisobutyronitrile (AIBN) 10:204, 208;21:746;24:16-18 Azocasein method 30:841 for proteolytic activity 30:841 Azocine 8:210 synthesis of 8:210
Azodicarbonyldipiperidine 19:225 Azodicarboxylate 22:198 Z-Azoene 23:459 Azohydroperoxide 9:580otAzoles 22:58 Azomethine ylide cycloadditions 1:329, 330 by aziridine thermolysis 1:329, 330 intramolecular 1:329,330 Azomethine ylides 1:331-332 by 1,2-H shifts 1:331-332 formation of 1:324-344 generation of 1:324,339 preparation by aziridine opening 1:328-331 preparation by desilylation 1:324-328 preparation from c~-amino acids 1:331-338 Azomonas macrocytogenes 19:814 4-Azoniaspiro [3,3] heptane-2,6 diol 18:677 from Chara globularis 18:677 Azospirillum lipoferum 4:197 Azotobacter vinelandii 26:1151,1152, 1211 Azotobactins 19:812 Azoverdin 19:0" 1 Azukisapogenoi B 25:97 Azukisaponin 25:95 Azukisaponin II 25:95,104,105,115, 116,118,203,226 Azukisaponin V 25:104,115,116,118, 120,203,226 Azukisaponin VI 25:97,104 Azulen 26:305 Azulene quinones 14:314 Azulenes 14:332 autooxidation of 14:332 electrochemical oxidation of 14:325 oxidation of 14:332-334 prostaglandins 16:367 Bsynthesis of 16:367
89 B/C-trans-morphinan 12:464-471 diastereoselective synthesis of 12:464-471 B4-2313 A, B 21:411,412 B-90063 25:842 Baadische Anilin 28:71 vitamin A synthesis by 28:71 Babesia bigemina 28:398 Babesia bovis 28:398 Babesia sp. 26:694,835;28:398 BABS 21:752-754 BABS-M-receptor complex 21:754 Babylonia japonica 11:724 Baccatin I 11:4,9;12:179 Baccatin III 11:3,4,179,180;12:179, 180;20:81 ;22:218;23:490,491 ;25:245 Baccharin 30:735 structure of 30:735 Baccharinoids 30:743 Baccharinol 30:736 structure of 30:736 Bacchariolide A 30:716 structure of 30:716 Bacchariolide B 30:717 structure of 30:717 Baccharis anomala D.C. 30:750 microsomal activation by 30:750 Baccharis articulata 15:22;30:706,708, 723,743,744,750 articulin from 30:708 as antidiabetic 30:706 as decoctions 30:706 as infusions 30:706 bacchotricuneatin A from 30:708 barticulidiol from 30:708 [3-caryophyllene from 30:723 in treatment of rheumatism 30:744 in ulcers 30:744 inhibition of viral infectivity by 30:743 neo-clerodane type 30:708 nerolidol from 30:723 use as raw material for preparation of phytotherapeutic drugs 30:750 Baccharis boliviensis 30:711,712,730, 742
coumaric acids 30:730 ent-clerodane derivatives from 30:711 ent-clerodane furanoditerpenoid from 30:711 labdane-type diterpenes from 30:712 trypanocidal effect of 30:742 Baccharis calliprinos Grised 30:746 Baccharis calvescens D.C. 30:731 p-hydroxyacetophenones from 30:731 Baccharis cassinaefolia 30:708 bacchotricuneatin A from 30:708 Baccharis conferta 30.704,740,748 against Escherichia coli 30:740 antibacterial activity against Micrococcus luteus 30:740 as laxative 30:705 for stimulating urination 30:705 in treatment of baldness 30:705 in treatment of gastrointestinal illnesses 30:748 in treatment of insect bites 30:705 in treatment of stomach aches 30:704 triterpenoid oleanoic acid methyl ester from 30:740 Baccharis cordifolia 22:348;30:705, 717,719,733,743,745,751 as anti-inflammatory 30:705 baccharinoids from 30:717 extract of 30:733 in toxic disease 30:751 in treatment of horse's external parasites 30:705 macrocyclic trichothecenes from 30:743 roridins from 30:717,751 schottenol glucoside from 30:719 to treat horse's distemper 30:705 toxins from 30:751 ursolic acid from 30:719 uvaol from 30:719 verrucarins from 30:717 Baccharis cordobensis 30:722 cadinol from 30:722
90 cubenol from 30:722 essential oil from 30:722 nerolidol from 30:722 Baccharis crispa 30:722,723,739,743, 744,745,750 antibacterial activity against 30:739 antifungal activity against 30:739 essential oil from 30:722 in treatment of liver diseases 30:744 nerolidol from 30:722 as phytotherapeutic drugs 30:750 Baccharis dracunculifolia 30:723,730 dracunculifosides A-J from 30:730 Baccharis floribunda 30:706 Baccharis gaudichaudiana 25:251,269; 27:14,24,25 ;30:706,734 as antidiabetic material 30:706 arabinoside gaudichaudioside A from 15:21 as decoction 30:706 as infusion 30:706 gaudichandioside A from 27" 14, 24,25 in P-388 lymphocytic leukemia cells 30:734 Baccharis genistelloides 25:941; 30:706,711,720,733,739,740,743, 744,746,748-750 against HSV-1/VSV 30:743 against Staphylococcus aureus 30:739 anti-inflammatory constituents from 30:746 against Candida albicans 30:739 against gram-positive bacteria 30:739 antimicrobial activity of 30:740 antimutagen constituents from 30:733 apigenin from 30:733 as anti-inflammatory material 30:750 as antithermic 30:706 cirsimaritin from 30:733 diterpene lactone from 30:740
effects on bile duct 30:750 effects on bone marrow 30:750 effects on cardiac function 30:750 effects on liver 30:750 effects on pancreas 30:750 effects on serum lipids 30:750 genkwanin from 30:733 hispidulin from 30:733 m anaemia 30:706 m diabetes 30:706 m diarrhoea 30:706 m digestive disorders 30:706 m indigestion 30:706 m inflammation 30:706 m intestinal worms 30:706 in leprosy 30:706 an liver disorders 30:706,733,749 in malaria 30:706 in rheumatism 30:733 m sore throat 30:706 m tonisilitis 30:706 in ulcers 30:706 m urinary disorder 30:706 [3-sitosterol from 30:720 stigmasterol from 30:720 structure-activity relationship of 30:733 use in liver diseases 30:749 use in wounds 30:744 Baccharis genus 30:707,733,738 antibacterial activity of 30:738 antifungal activity of 30:738 constituents of 30:707,733 diterpenoids from 30:733 epi-methyltrineracetal from 30:707 flavonoids from 30:733 methyltrineracetal from 30:707 neo-clerodane type diterpene 30:707 secondary metabolites from 30:738 Baccharis glutinosa 30:704,739 antimicrobial activity of 30:739 as contraceptive 30:704 for digestive disorders 30:704 for gynecological disorders 30:704
91
for skin diseases 30:704 in treatment of infectious diseases 30:739 in weight reduction 30:704 to clean wounds 30:704 to treat scalp diseases 30:704 Baccharis grisebachii 30:705,730,733, 739,745 coumaric acids from 30:730 3-(3,3-dimethylallyl)-p-coumaric acid from 30:730 extract of 30:733 for decoctions 30:705 for poultices 30:705 for wound healing 30:705 inhibitory activity of 30:745 spectrum of action of 30:739 Baccharis halimifolia L. 30:718 baccharis oxide from 30:718 Baccharis heterophylla 30:718 oleanolic acid from 30:718 Baccharis incarum 22:352;30:709,744 bincatriol from 30:709 3'-methoxycalicopterin 7'methyl-sudachitin from 22:352 neo-clerodane diterpenoid from 30:709 Baccharis intermixta Gardn. 30:713 Baccharis L. 30:704 biological activities of 30:704 traditional uses of 30:704 Baccharis latifolia 30:721,731 oil from 30:721 p-hydroxyacetophenones from 30:731 Baccharis macraei 30:710 clerodane derivatives of 30:710 hardwickiic acid from 30:710 hautriwaic acid from 30:710 Baccharis magellamica (Lam.) 30:731 Baccharis medullosa 30:712,744 as anti-inflammatory material 30:744 Baccharis megapotamica 30:717,736, 751 activity against P-388 leukemia 30:736 against human carcinoma 30:736 as cytotoxic agents 30:717
baccharin from 30:736 baccharinoids from 30:717 baccharinol from 30:736 bioassay-guided fractionation of 30:736 extract of 30:736 isobaccharin from 30:736 isobaccharinol from 30:736 roridins from 30:717 toxins from 30:751 verrucarins from 30:717 Baccharis multiflora 30:705,713 against catarrhs 30:705 as infusion 30:705 ent-kaurenic acid from 30:713 ent-kaurenol from 30:713 for urinary problems 30:705 kaurane-type diterpenoids from 30:713 Baccharis myriocephala D.C. 750 Baccharis myrsinites 30:709,718,729 clerodane diterpenoid from 30:709 coumaric acid from 30:729 maniladiol from 30:718 oleanolic acid from 30:718 structure elucidation of 30:709 Baccharis myrtilloides 30:723 germacrane D from 30:723 Baccharis notosergilla 30.705,739,740, 742,743 against gram-positive organisms 30:740 against Trypanosoma cruzi 30:742 antibacterial activity of 30:739, 740 antifungal activity of 30:739 as digestive agent 30:705 as diuretic 30:705 essential oil of 30:740 in folk medicine 30:705 Baccharis oxide 30:717 baccharis oxide from 30:706 structure of 30:717 Baccharis oxydonta 30:711,728 ent-labdane diterpenes from 30:711
92 pinobanksin from 30:728 pinocembrin from 30:728 Baccharis paniculata 30:710,712,731, 740 acetylenic lactones from 30:731 against phytopathogenic fungi 30:740 for antifungal activity against human pathogens 30:740 3-methyl ether flavone 30:740 neo-clerodane diterpenoids from 30:710 prenylated coumarin from 30:740 Baccharis pedunelata 25:251 Baccharis petiolata 25:251 Baccharis pingraea 30:712 furolabdane diterpenoids from 30:712 furolabda-6,8-dien- 17-oic acid 30:from 30:712 furolabda-7-en-17-oic acid from 30:712 Baccharis pteroniodes 30:711 ent-clerodane diterpenoids from 30:711 neo-clerodane diterpenoids from 30:711 Baccharis ramoisissima 30:713 ent-kaurenic acid from 30:713 ent-kaurenol from 30:713 Baccharis rhetinoides 30:746 anti-inflammatory flavonoids from 30:746 homoeriodictyol from 30:746 Baccharis rubricaulis 30:706 for treating mucous ailments 30:706 Baccharis rufescens 30:723,744 as anti-inflammatory agent 30:744 limonene from 30:723 nerolidol from 30:723 Baccharis salicifolia 30:705,707,718, 72i,722,731,732 t,accharis oxide from 30:718 e ~t-clerodane derivatives from 30:707 essential oil from 30:722
for diarrhoea 30:705 for dysentery 30:705 for inflammation 30:705 germacrane D from 30:722 oils from 30:721 prenyl derivatives from 30:731 Baccharis salicina 30:715 bacchariolides from 30:715 chemical analysis of 30:715 guaianolides from 30:715 Baccharis santelicis 30:709 Baccharis sarothroides 30:705,710,733 centaureidin from 30:733 cytotoxic flavonols from 30:733 3,4'-dimethoxy-3',5,7trihydroxyflavone from 30:733 hautriwaic acid from 30:710 2[3-hydroxyhautriwaic acid from 30:710 identification of 30:733 inhibitory activity against human carcinoma 30:733 Baccharis scoparia 25:251;30:711,712 labdane aldehyde from 30:712 Baccharis serraefolia 30:705,720,739, 748 against Candida albicans 30:739 against Staphylococcus aureus 30:739 against gram-positive organisms 30:739 mechanism of action of 30:748 phytol from 30:720 [~-sitosterol from 30:720 spasmolytic action of 30:748 to treat diarrhoea 30:705 use in gastrointestinal illnesses 30:705 Baccharis species 29:580;30:706,707, 711,737,740,741,750, antineoplastic activity of 30:737 apigenin from 30:740 assay-guided fractionation of 30:737 for preparation of phytotherapeutic drugs 30:750 genkwanin from 30:740 pentacyclic triterpenoids from 30:737
93 toxicological evaluation of 30:750 Baccharis spartioides 30:715,723 essential oil of 30:723 spartidienedione from 30:715 Baccharis sphaerocephala 30:715 amorphane sesquiterpene y-lactol from 30:715 O-methylbaccharocephol from 30:715 Baccharis sternbergiana 30:712 Baccharis timera 7:427 Baccharis tola 30:714,725 ent-4c~-hydroxy- 19-norbeyer- 15ene from 30:714 ent-beyer- 15-en- 17,19-ol from 30:714 ent-beyerane-type diterpenoids from 30:714 flavone from 30:725 Baccharis tricuneata 30:706,708,719 c~-amyrin acetate from 30:719 bacchotricuneatin A from 30:708 for diabetes 30:706 for skin infections 30:706 friedelin from 30:719 13-sitosterol from 30:719 ursolic acid from 30:719 Baccharis trimera 30:706 as antithermic agent 30:706 for digestive disorders 30:706 for liver disorders 30:706 use in anaemia 30:706 use m diabetes 30:706 use m diarrhoea 30:706 use m indigestion 30:706 use m inflammation 30:706 use m intestinal worms 30:706 use in leprosy 30:706 use m malaria 30:706 use m sore throat 30:706 use m tonsilitis 30:706 use in ulcers 30:706 use m urinary diseases 30:706 Baccharis trinervis 30:705,725,743 against human immunodeficiency virus 30:743 antiviral activity of 30:743
apigenin from 30:725 flavones from 30:725 flavonol from 30:725 for gastrointestinal disorders 30:705 in dizziness 30:705 in MT-2 infected cells 30:743 in treatment of edema 30:705 in treatment of high fever 30:705 in treatment of muscle cramps 30:705 in treatment of sores 30:705 in treatment of typhoid fever 30:705 inhibition of HSV-1 30:743 pectolinaringenin (5,7dihydroxy- 6,4'-dimethoxyflavone) from 30:725 pe dunletin (5,4 '-dihydro x y- 3,6,7trimethoxyflavone) from 30:725 salvigenin (5-hydroxy-6,7,4 'trimethoxyflavone) from 30:725 Baccharis triptera Mart 30:749 in gastrointestinal disorders 30:749 in gastrointestinal hyperactivity 30:749 Baccharis tucumanensis 30:705,733, 744 anti-inflammatory action of 30:745 as abortive agent 30:705 extract of 30:733 in carrageenan foot edema test 30:745 role in croton oil induced mouse ear edema test 30:745 Baccharis uncinella D.C. 30:723 essential oil from 30:723 Baccharis vaccinoides 30:705,710,739 against Candida albicans 30:739 against Staphylococcus aureus 30:739 antimicrobial activity in vitro 30:739 for gastrointestinal disorders 30:705
94 hautriwaic acid from 30:710 2[3-hydroxyhautriwaic acid from 30:710 Baccharis varians 30:728,729 3-acetoxyflavanones from 30:728 Bacchotricuneatin A 30:709 structure of 30:709 Bacillarophyceae 6:13 Bacillus acidcaldarius 23:92 Bacillus antharacis 12:400 Bacillus aurantinus 5:601 Bacillus calmette-Guerin (BCG) 25:462,497 Bacillus cereus 7:413;22:273,274; 23:344,473 ;25:259;26:1091 Bacillus ganera 29:311 Bacillus macerans 27:8,365 Bacillus marinus 23:258 Bacillus megaterium 10:585;12:104; 23:76;27:365 Bacillus pumilis 7:70,308,390;30:693 Bacillus sp. 12:103;21:391,599;25:155 Bacillus stearothermophilus 29:266 Bacillus subtilis 5:302,304,368,418, 308,353;8:353;10:117,104,400,345, 692,290,556,559;18:778;21:237,262, 266,267,284,610;22:627,628;23:41, 344,473 ;24:713;25:220,258-260,765, 770,776-779,782,789,792,863 ;26:79, 333,334,1093 ;28:223,693 ;29:272; 30:629,693,738 antifungal activity against 30:738 caffeic acid inhibition by 30:225 effects of phenols on 28:223 of drummondins A-C 30:629 of phloroglucinols 30:629 role of 30:225 Bacillus thiaminolyticus 15:390 baciphelacin from 15:390 Bacillus thuringiensis vat. kurstaki 28:404 Baciphelacin 15:388,390,409,410 Bacitracin 9:413 ;26:366,374 Backbone rearrangements 7:159, 161-166 Bacogenin A1 23:503,511 transformation of 23:503,511
Bacogenin A3 23:503 Baconipyrones A-D 17:25 Bacopa monnieri L. 22:513 for epilepsy 22:513 Bacopa monnira L. 22:513;23:489,499 for epilepsy 22:513 Bacopasaponin A 23:503,504 13C-NMR chemical shifts of 23:509 ~H-NMR chemical shifts of 23:504 Bacopasaponin B 23:503 ~3C-NMR chemical shifts of 23:509 ~H-NMR chemical shifts of 23:506 Bacopasaponin C 23:503,507 13C-NMR chemical shifts of 23:510 IH-NMR chemical shifts 23:507 Bacopasaponin D 23:503,510 13C-NMR chemical shifts of 23:510 Bacteria 9:537-557 siderophores from 9:537-557 Bacterial cell wall 6:385,395,397,406 Bacterial effects 30:152 of Streptococcus mutans 30:152 Bacterial growth inhibitors 17:101 Bacterial hydrolysis 30:305 of sugar 30:305 Bacterial infections 30:408 Bacterial origin 28:434 acaricidal agents of 28:434 Bacterial polysaccharides 4:195 L-glycero-D-mannoheptose in 4:195 Bacterial reverse mutation test 27:303 Bactericidal effect 26:1095 of HMTP on Sacchomyces epidermidis 26:1095 Bactericidal properties 21:225 Bactericidal/permeability-increasing protein 27:807 Bactericides 28:390 used of essential oil 28:415,390 Bacteriorhodopsin 4:526,720,823 (2S,2'S)-Bacterioruberin 30:517 structure of 30:517
95
Bacterioruberin 7:355-357;20:599; 30:523 as cell membrane stabilisers 30:523 Bacterium pseudomonas 9:322 Bacteroides fragilis 14:107 (-)-Bactobolin 16:22 Bactobolin 16:3 antibacterial activity of 16:3 antitumor antibiotic 16:3 from Pseudomonas yoshitomiensis Y-12278 16:3 total synthesis of 16:3-26 Bademi 23:659 Baekhousia citriodora 25:132 Baeyer-Meerwein rearrangement 24:30-32 Baeyer-Villiger oxidation 21:301,417; 24:30-32,42,43,191,192 Baeyer-Villiger reaction 27:94 9-hydroperoxy- 10,12,15octadecatrienoic acid by 27:74 Baeyer-Villiger rearrangement 4:139, 153,647,667;8:154,597,598;27:74 Baeyer-Villiger ring expansion 13:601 Bafilodides 26:495 Bafilomycin A1 26:453 Bafilomycin B2 26:453 Bafilomycin C1 26:453 Bahiensol 29:253 antimicrobial activity of 29:253 Baicalein 22:509;25:593,595;27:435; 29:572,581,584 ;30:55,69-72,288 anti-inflammatory actions of 30:72 as anti-allergic 30:71,72 biological activity of 27:435 effects on HIV- 1 protease 29:572,581 effects on LELA 29:584 effects on MMP 29:581 inhibitory action of 30:70 Baikal 23:656 Baiyumine A 13:348,349 from Citrus grandis 13:348,349 Baiyumine B 13:350 from Citrus grandis 13:350
(+)-Baiyunol 1:666-669 synthesis of 1:666-669 thermal glycosidation of 8:362 Baiyunoside 27:14,25 structure of 27:15 Baiyunoside 1:666-670 synthesis of 1:666-670 from Phlomis betonicoides 15:20 Bai-yun-shen 1:666 baiyuoside from 1:666 Bakankoside 6:503 from Strychnos vacacoua 6:503 Bakankosine 26:101,102 chemical transformation of 26:101,102 Baker's methodology 21:442 Baker's conditions 12:46,47 Baker's yeast 4:158,263,324,325,340, 341,410,542,543,552,553 ;6:13; 10:410;13:58,59,307,309;20:573, 593,818,820;25:143,145 Baker's yeast reduction 13:662,176 Balaenonol 5:744,747-749,149,150,152 Balam 23:652 Balanitaceae 7:426,427 Balanites aegyptiaca 7:426 Balanocarpol 26:556,561 Balanocarpus zeylanicus 23:547 Balanol (44) 27:868,869 Balanophonin 20:642 from Balanophora japonica 20:642 Balanophora elongata 29:583,586 Balanophorajaponica 1:666 balanophonin from 20:642 Balanus amphirib 25:783,784,785 Balanus amphitrite 21:366 BALB/3T3 12:400 staurosporine activity against 12:400 BALB/c mice 28:534;30:592 epidermal cell culture of 30:592 Meth A sarcoma in 28:534 Balchanolide 7:230 Baldrinal 7:458,459 Baldwin's rule 14:792,793 Baleabuxidine 2:205 Baleabuxoxazine-C 2:205
96
Ballota nigra 30:268 flavonoids from 30:268 Balsamiton 27:591 Balsamodendron mukul 5:695 Balsamodendron sp. 22:513 for epilepsy 22:513 Baluchistamine B 20:270 Bamboo shoots 6:187 GA19 from 6:187 Bamicetin 4:241,243-245 Ban condensation 1:135 Banerjee 29:174 pisiferic acid synthesis by 29:174 Banerjee and Az6car 29:208 triptolide synthesis by 29:208 Banerjee et al. 29:194,215 Carnosic acid synthesis by 29:194 miltirone synthesis by 29:215 Banksia grandis 19:246 Bannucine 5:167-169;9:185,186 Banwell 29:377,378 allocolchicinoids total synthesis by 29:377,378 Baogongteng A 21:751,752 synthesis of 21:751,752 Baogongteng C 21:751 B AP (6-benzylaminopurine) as cytokinin 7:90,94 Baphia nitida 21:616 Baptisiasaponin 25:95 Barbamide 25:757,785,786,889,890 Barbatol 25:250 Barbatosides B 26:56 analgesic activity of 26:56 as anti-inflammatory agent 26:32 Barbatosides A 26:56 analgesic activity of 26:56 as anti-inflammatory agent 26:32 Barbilophzia hatcheri 5:730 Barbilophzia lycopodioides 5:730 Barbiturates 25:528 Barceloneic acids 24:450 as human FPTase inhibitors 24:450 structures of 24:450 Barley 28:260 syringic acid in 28:260 vanillic acid in 28:260
Barley endosperm assay 6:181 Barnacle settlement inhibitors 17:103 Barosma betuling 27:375 Barosma crenulata 27:375 Barrett's approaches 12:9-11 for oxahydrindene subunit 12:9-11 ofavermectins 12:9-11 Barrigenic acid 7:132 from Barringtonia acutangula 7:132 R1-Barrigenol 21,22-di-O-angelate 7:139,141 Barrigenol A1 21:673 Barringtogenic acid 7:132 from Barringtonia racemosa 7:132 Barringtonia acutangula 7:132 barrigenic acid from 7:132 barringtonic acid from 7:132 barrinic acid from 7:132 tangulic acid from 7:132 Barringtonia racemosa 7:132;22:514 barringtogenic acid from 7:132 for epilepsy 22:514 Barringtonia sp. 7:132,133 triterpenes of 7:132,133 Barringtonia speciosa 7:132 anhydrobartogenic acid from 7:132 bartogenic acid from 7:132 19-epi-bartogenic acid from 7:132 Barringtonic acid 7:132 from Barringtonia acutangula 7:132 Barrollier reagent 19:755 Barticulidiol 30:709 structure of 30:709 Bartlett demethylation 8:119 Bartlett method 25:435 Bartlett pear ester 10:152 Bartogenic acid 7:132 from Barringtonia speciosa 7:132 19-epi-Bartogenic acid 7:132 from Barrintgonia speciosa 7:132
97 Barton oxidation 13:72 9-BBN (9-borabicyclo-[3.3.1 ] nonane) 13:72 Barton radical decarboxylation 18:75, 340 Barton reaction 14:160 Barton reduction 12:303 Barton's modification 19:135 Barton-Crich's decarboxylative oxygenation 24:43,44 Barton's procedure 6:282-288,607 Barton's protocol 6:21 in free radical deoxygenation 6:21 Barton's reaction 6:228,230,231 Barton-type deoxygenation 20:71 Base promoted cyclisations 4:541 of aryl halides 4:541 Base-catalysis 16:220 Base-catalyzed equilibration 14:460 Base-induced rearrangement 12:91 mechanism of 14:372-374 of hydroazulene mesylates 14:22-25 of hydronaphthalene- 1,4-diol monosulfonate esters 14:356 of hydronaphthalene tosylates 14:368-370 Basidiomycetes 9:220,317;21:187;
18:813,814;25:129,150
fruiting body formation 1:680 glycosphingolipids of 18:813,814 Basidiomycetous fungus 30:403 in folk medicine 30:403 mode of antiviral activity of 30:403 Basidiomycota 22:246 Basidiomycotina 9:202;23:109 Basilicum polystachyon 22:514 for epilepsy 22:519 Basilicum polystachyon 22:514 for sedative in convulsions and epilepsy 22:514 Bastadin 10:630,632,633-638;25:719, 720 Bastadin-6 10:630,636-638 Bastaxanthin 6:150;10:153
Bastaxanthin B 28:714 as novel carotenoid sulfate 28:714 Bastaxanthin C 28:714;30:526,527 as novel carotenoid sulfate 28:714 structure of 30:526,527 Bastaxanthin D 28:714 as novel carotenoid sulfate 28:714 Bastaxanthin E 28:714 as novel carotenoid sulfate 28:714 Bastaxanthin F 28:714 as novel carotenoid sulfate 28:714 Bastaxanthins 30:526 Bastaxanthins C,B,D,E,F 9-BBN 6:20 reaction with 13-furanone 6:20 Batasin 23:348 Batasin I 23:342 Batrachotoxinin 11:244;21:73 Batramiaflavone 20:283 Batzella sp. 25:708,760,774,790,822, 852;27:881 ;28:715 Batzella sponge 28:685 against Candida albicans 28:686 antifungal activity of 28:686 Batzelladine A 25:709 Batzelladines 25:708 Batzelline A 25:822 Batzelline B 25:822 Batzellines 25:707 Batzellines-isobatzellines 25:822 Baudoin-Gu6ritte 29:407 rhazinilam synthesis by 29:407 Bauhinia bauhinioides 29:603 Bauhinia microstachya 29:573 Bauhinia mollis 29:603 Bauhinia pentandra 29:603 Bauhinia variegata 29:603 Bavachalcone 28:228 biological activity of 28:228 Bayberry 13:660 Bayer-Villager oxidation 25:425 24-epi-catasterone by 25:425 Bayogenin 7:432 molluscicidal activity of 7:432 Bayogenin bidesmosides 21:634
98 Bazzanene 9:212,213,308,309,520,521 Bazzanenone 10:308,309 Bazzania 21:281 BBE (berberine bridge enzyme) 11:204 BBN 4:116,117 reduction with 4:116,117 trans-BC-ring fusion 12:205 stereochemistry of 12:205 BCA method 25:433 BCAs 21:182,191,193,202,203,218, 224,226,229,240 B-cell leukaemia 21:137 BCG/LPS induced hepatotoxicity 25:471 BE-13793C 12:366,370,396 antitumor activity of 12:396 topoisomerase I and II inhibitors of 12:370 Beaucage sulfurizating agent 13:269 Beauvaria bassiana 23:20,21,34; 28:397,404 Beckman fragmentation 19:486 of anti-oxime 19:486 of erythromycin-9-oxime 13:160,161 of oxacyclopentanone ring 16:221 of oxime 16:240,330;19:14,498 Bee parasites 28:387 formic acid in 28:387 Beer's law 15:423 Beesia 25:180 Beet armyworm 12:397 Beewax 19:246 Begonia plebeha 19:764 Behavioral dysfunction 30:368 effect of serotonergic neurotransmission on 30:368 Behilic acids 22:612 Beta-eudesmol 24:883-887 p-phenylene-polymlethylene bisammonium derivatives 24:883-887 Belemnitella sp. 13:330 Belladonna 22:422 Bellis perennis 21:662 Bellus rearrangement 8:205 Bemangovitra 26:1037,1038 Benanomicin A 22:62
Benanomicin B 22:62 Bencimidazol 25:669 Bengamide A&B 26:485 Bengazole A 26:488 Benincasa cerifera Savi 22:514 for epilepsy 22:514 Benincasa hispida 22:513 use for epilepsy and hysteroepilepsy 22:513 Benthiozepines 25:534 diltiazem 25:534 Benz [a] anthracene antibiotics 11:134 antibacterial activity of 11:134 antitumor activity of 11:134 Benzal malonates 9:224-227 inhibitory activity of 9:224-227 synthesis of 9:224-227 Benzaldehyde 28:406 acaricidal properties of 28:406 Benzaldehyde acetal 14:477 chromium tricarbonyl complex 14:477 from (2R,3R)-2,3-butanediol 14:477 with trimethyl aluminum and titanium tetrachloride 14:477 Benzamido-2-deoxy-[3-D-glucopyranosyl)7-2-theophylline 4:238 Benz-annulation reaction 1:505,506 Benzatropine 22:732 3-Benzazepine derivative 6:474,484 Benzazepines 1:169;25:534 3-Benzazocine 6:469,471 synthesis of 6:469 2-Benzazocine N-oxide derivative 6:472 Benzazocines 1:192,193 ;6:468-471,442 3-Benzazonine derivative 6:475,476 Benzene ring 27:355 steric effect of 27:355 Benzene thiol 11:358 1,2-Benzenedithiol 11:357 1,2,4,5-Benzenetetracarboxylate 11:124 Benzidine 7:457 Benzilic-type rearrangement 3:226 Benzimidazole antidote 22:464 Benzimidazoles 12:3 Benzo [a] pyrene 7:8 carcinogenicity of 7:8
99 Benzo [a] pyrene oxides 7:8 absolute configuration of 7:8 from benzo [a] pyrene 7:8 Benzo [a] pyrene-(-)-7R,8R-dihydrodiol 7:8,9 Benzo [a] pyrene-7R,8S-dihydrodiol9S, lOR-epoxide 7:8,9 8,13-Benzo [a]naphthacene quinone 11:123 from naphthacene glutarate 11:123 Benzo [c] phenanthridine alkaloids 14:769-803 biomimetic synthesis of 14:769-803 biosynthesis of 14:771-773 from protoberberines 14:769-803 oxygenative conversion of 14:779-784 Benzo[c]naphta [1,2-E] azonine derivative 6:481 Benzo [c]phenanthridine alkaloids (QBA) 1:187,542;27:819 biological activities of 27:178 chemistry of 27:155 Benzo[c]phenanthridines 5:42 Benzoacetonitriles 25:719 Benzochromones 18:978 Benzocyclobutanol 14:685 Benzocyclobutanone 14:685 synthesis of 14:685 via (2 +2) cycloaddition 14:685 Benzocyclobutenes 3:434-437 Benzodiazapines 21:101 ;22:508,666; 25:528;27:803 Benzodiazepine receptors 22:26 Benzodioxan 8:399,401 1,6,5-Benzodioxazonine 6:472 from 1,5-benzoxazocine N-oxide 6:472 Benzofuran 20:282;29:763 2-(p-hydroxybenzyl)-6-methoxybenzofuran as 29:767 structure of 29:767 Benzofuran lignans 26:253 Benzofuran neolignans 26:202 Benzofuran-2-carboxylic acids 30:221 Benzofuranoid terphenyls 29:279 2,3 ', 8-tri- O- acetylc yc lovariegatin
as 29:283 3 '-demetho xy-6 '-de smethyl- 5 'methoxycandidusin B as 29:282 antifeedant activity of 29:282 as 5-LOX inhibitor 29:280 as antioxidative component 29:281 benzofuranoid arenarin A as 29:282 benzofuranoid ganbajunin B as 29:280 candidusins as 29:281 cycloleucomelone as 29:279,283 cycloleucomelone leucoperacetate as 29:279 cycloleucomelone leuco-tetraacetates as 29:279 cycloleucomelone leucotriacetate as 29:279 desmethylcandidusin B as 29:282 effect on DNA, RNA, protein synthesis 29:281 in antibacterial assay 29:281 rotoleucomelone as 29:279 Benzoic acid 23:744,77125:655,660, 928,929 derivatives of 23:744,771 Benzoic acid-2 hydroxylase 25:660,669 Benzoirithiepin 25:834,835 Benzomorphans 6:471 2,6-bridge 3-benzazocine in 6:471 Benzopentathiepin lissoclinotoxin B 25:833 Benzophenanthridine alkaloids 21:108 Benzophenanthridine skeleton 21:69 Benzophenone 27:331 4H-1-Benzopyran-4-one ring system 21:123 Benzopyranopyrrole chromphore 25:776 1,2-Benzopyrone 23:337 Benzoquinone derivatives 7:183,184 1,4-Benzoquinones 16:547-570 enantiospecifir reactions of 16:547-570
100
stereospecific reactions of 16:547-570 Benzoquinones 5:774-778;20:273; 23:341 Benzosampangine 23:3,5,42 biotransformation of 23:3,5,42 Benzosampangine-[3-glucopyranoside (BZSAMM1) 23:25 Benzothiadiazole 26:846 Benzotrithiane 25:833 Benzotrithiepin S-oxides 25:834 B enzotrithiepin- 5-(methylthio) varacin 25:834 2H-3,6-Benzoxazecine derivatives 6:486 1H-2,6-Benzoxazecine derivatives 6:486 2,3-Benzoxazepine derivative 6:468 from cis-(+)-laudanosine N-oxide 6:468 Benzoxazinoid acetal glucosides 27:191-194 chemical synthesis of 27:196,207-210 enzymatic degradation of 27:191-196 Benzoxazinoids 23:342;27:211 biological activity of 27:211 Benzoxazinone acetal glucosides 27:187-190 Blepharin 27:188 DHBOA-Glc 27:188 DIBOA-Glc 27:188 DIMEBOA-Glc 27:188 DIMBOA-Glc 27:188 GDHBOA 27:188 GDIMBOA 27:188 GHBOA 27:188 GHDMBOA 27:188 GHMEBOA 27:188 GHMBOA 27:188 GIMEBOA 27:188 HBOA-Glc 27:188 HDMBOA-Glc 27:188 HM2BOA-Glc 27:188 HMBOA-GIc 27:188 occurrence of 27:187-190 Benzoxazinone acetal glucosides 27:224,225
biological role of 27:224,225 Benzoxazinones 27:185-225 biological activity of 27:185-225 biological role of 27:224 defoxification of 27:218-222 effects on animal organisms 27:212-214 synthetic access to 27:185-225 Benzoxazione aglucones 27:190-191, 195,196-207 as equilibrium of enantiomeric cyclohemiacetals 27:194 blepharigenin 27:191 chemical synthesis of 27:196-205 chemical synthesis of 27:196-205 DHBOA 27:191 DIBOA 27:191,195,196 DIM2BOA 27:191 DIMBOA 27:191,195,196 HBoA 27:191 HDMBoA 27:191 HMBoA 27:191 synthesis of analogues 27:205-207 TRBoA 27:191 2,4-Benzoxazocine derivatives 6:469 by ring expansion 6:469 Benzoxazocine derivatives 6:468-471 by ring construction 6:468-471 by ring destruction 6:468-471 by ring interconversion 6:468-471 from c~-narcotine N-oxide 6:468 synthesis of 6:468-471 1,5-Benzoxazocine N-oxide 6:472 1,6,5-benzodioxazonine from 6:472 thermolysis of 6:472 Benzoxazolidone derivative 12:164,166 boron enolate of 12:164,166 C4-alkylation by 12:164,166 stereoslective 12:164,166 Benzoxazolin-2(3H)-ones 27:193 4-ABOA 27:193 BOA 27:193 4-C1-DMBOA 27:193 5-C1-DMBOA 27:193
101 DMBoA 27:193 MBOA 27:193 Benzoxazolin-2-one 7:191,192 2(3H)-Benzoxazolone 23:342 Benzoxazolones 23:342 2,5-Benzoxazonine 6:468-471 carbocation intermediate in 6:473 derivatives of 6:476,47 photosolvolysis of 6:475,476 synthesis of 6:473 X-ray analysis of 6:476,477 Benzoxicins 5:798;10:210 N-Benzoyl Cls-phytosphingosine 18:461 Benzoyl compounds 30:236 structure of 30:236 N-Benzoyl phytosphingosine 18:462 3-Benzoyl propionic acid 10:406 Benzo yl- 1,2:5,6-di- O-isoprop ylidene- aD-3-O-glucofuranose 6:285,286 4-O-Benzoyl- 1,2-cyanoethylidene-ot-Lrhamnose 14:242 Benzoyl- 16-(+)-N-acetoxycycloxobuxidine-F 2:200,201 Benzoylation 1:415,417,289,290,341 N-Benzoylbaleabuxidine-F 2:205 N-Benzoylbuxidienine 2:205 N-Benzoylcarbamate 14:569 cyclization of 14:569 from 2,3-epoxy alcohol 14:569 2-oxazolidinone from 14:569 N-6-Benzoyldeoxyadenosine derivatives 4:278 N-B enzoyldihydrocyclomicrophylline-F 2:207 Benzoylgomisin O 26:197 5-( 1-Benzoylindol-3-ylmethyl)pyrrolidinone 13:130,131 Benzoylisogomisin O 26:247 N-B enzoyl-iso-serinate 12:223,225 O-Benzoylnormacusine 13:386 1-B enzo yloxy- 3-[ ( 3- guaiazulenyl) methyl]-5-isopropyl-8-methylazulene 14:324 N-Benzoylpyrrolidinone 13:121 N-Benzoylpyrrolinone 8:212,213 synthesis of 8:212,213 Benzthiazole 25:896
(R)-(+)-Benzyl 1-(2-methoxy)-naphthyl sulfoxide 10:684,685 ot-Benzyl 1-asparaginate 12:121 (S)-Benzyl 2,3-epoxypropyl ether 10:410,411 from D-mannitol 10:410,411 Benzyl 2-O-methanesulfonyl-13-Darabinopyranoside 14:50 Benzyl 5-amino-5-deoxy-2,3-Oisopropylidene-ot-D-mannofuranoside 10:541 Benzyl benzoate 28:416 against Psoroptes 28:416 against Sarcoptes mites 28:416 against Sarcoptes scabiei 28:416 effectiveness of 28:416 in mange control 28:416 Benzyl bromide 22:228 ot-Benzyl glycosides 6:390-395 of N-acetylmuramic acid methyl ester 6:395,399 of MurMAc 8-1actones 6:390-395 reactions of 6:390-395 N-Benzyl lactam (CGP-42700) 12:388 Benzyl sulfinylcarbamate 1:23 Benzyl tolyl sulfone 11:349 1-Benzyl- 1,2,3,4-tetrahydroisoquinolone alkaloids 10:683-685 B enzyl-2,3-anhydro-[3-D-ribopyranoside 14:50 4, 0-Benzyl-2,3-O-bis (methoxy methyl)-L-threitol 11:233 4-O-Benzyl-2,3-O-isopropylidenethreose 10:128-130 1-Benzyl-2,6-dicyanopiperidine 6:433 alkylation of 6:433 decyanation of 6:433 2,6-dialkylpiperidine s from 6:433 6-O-(2- O-B enzyl- 3-de oxy- 3- etho xy carbonyl-amino-4,6-O-isopropylidene-a-D-glucopyranosyl)-N, N'diethoxycarbonyl-2-deoxystreptamino 14:145 1-Benzyl-3-methylnaphthalene 30:217 formation of 30:217 from phenylacetone 30:217
102 1-Benzyl-3-methylnaphthalene 30:217 formation of 30:217 from phenylacetone 30:217 Benzyl-3-oxohexanoate 12:293 with 3-(1-A~-pyrroliniumyl) propanal 12:293 Benzyl-4,6-O-benzylidene-3-deoxy- [3D-ribo-hexopyranoside 14:11,12 synthesis of 14:11,12 3-O-Benzyl-4-O-methyl-dopamine 22:490 Benzyl-5-deoxy-5-(ethyl phosphinothioyl) 3-O-compounds 6:374,375 (+)-8-O-Benzyl-6-deoxy-castanospermine 12:346 6-Benzyl-9-(3,4-anhydro-c~-ltalopyranosyl)a-denine 4:233,234 (R)-( ct-methylbenzyl)B enzylamide 22:286 6-Benzylamino-9-(2-acetamido-2deoxy- f3-D-glucopyra-nosyl) purine 4:238 6-Benzylaminopurine (BAP) 4:227,238; 7:90,94,95 O-Benzylation 12:327 Benzylation 6:268-270,287,288 N-Benzylation 7:41-43 of 1,4-dideoxy- 1,4-imino-Lallitol 7:41-43 Benzylbenzoate 9:399 Benzylcarbamate prodrug HMR 1826 21:176,177 preclinical development of 21:176,177 O-Benzyldiscretine 14:776,777 fagaronine from 14:776,777 Benzylhistamine 26:119 Benzylic hydroperoxide rearrangement 3:316-319 3,5-O-Benzylidenation 12:52,53 of (9S)-9-dihydroerythronolide A 12:52,53 3-Benzylidene camphor 4:663,664 Benzylidene glycal 10:344 N-Benzylideneaniline 10:679,680 2,4-O-B enzylidene-D-threose 6:354 (1R)- 1-[(dimethoxy) phosphinyl]-Dthreitol from 6:354
4,6-O-Benzylidene-ct-D-glucopyranoside 14:157 N-Benzylipiperidine 19:35 Benzylisoquinoline alkaloids 6:472; 24:895-897;25:541 inhibitory effect on tube formation 24:895-897 isoquinoline 25:530 papaverine 25:541 Benzylisoquinoline derivatives 6:477,478,480 dibenz[d,f]azonine derivatives from 6:477,478,480 Benzylisoquinolines 3:422 synthesis of 3:422 3-O-Benzylisovanillin 22:490 N-Benzyl-L-glutamic acid 12:312 Benzyllithium 8:6 alkylation of 8:6 Nb-Benzyloxotryptamine 26:118 2-Benzyloxy glucals 10:346 Benzyloxy(benzyloxycarbonyl)methyl)trimethylphosphonium 30:441 (-)-9-Benzyloxy-9-demethyl-7methoxynogarene 14:82 Benzyloxycarbonylation 12:478 N-Benzyloxycaronyl- 1-proline methyl ester 12:295 exo- 15-Benzyloxyhobartine 11:299,300 15-Benzyloxyhobartine derivative 11:298,299 Benzyloxyisoflavone 27:499 Benzyloxymethyl chloride 6:561 a-(2-Benzyloxypropionyl)-butyrolactone 8:287 N-Benzyl-p-toluensulfonamide 12:323 5-Benzylpyrrol-2(5H)-ones 13:113 4-O-Benzylresacetophenone 27:499 Benzylstrictosidine 26:117 Benzyltetrahydroisoquinoline 18:72,76; 25:824 Benzylthiocrellidone 25:832 N-Benzyltrifluoroacetamide 14:553,554 Benzylvincoside 26:117,138 Benzyne cyclization 4:541-551 Benzyne reaction 16:514 Beogradolide A 27:550 Beogradolide B 27:550 Berbamine 21:57,79,96,98,102;25:472
103
Berbamine alkaloids 25:476 Berbamunin 20:292 Berberidaceae 21:3;27:754 Berberideine 20:265 Berberine 1:212;13:660;21:57,84,96,97, 102,108,109,733 ;22:27,35 ;25: 528; 26:305,821,822,823 APT spectrum of 5:42,43 biosynthesis of 11:201-204 t3C-NMR spectrum 5:44 8,14-cycloberbine from 1:211 from Berberis sp. 7:88 from Berber& vulgaris 13:660 1H-NMR spectrum of 5:40 INEPT spectrum of 5:43,44 Berberine bridge enzyme (BBE) 11:204 Berberis koetineana 11:202 Berberis sp. 7:88 berberine from 7:88 Berberis stolomifera 20:292 Berberis vulgaris 13:660;25:476 Berdy database 19:759 Beresklet 23:655 (+)-[3-cis-Bergamotene 16:235 cis-Bergamotene 16:235,236 c~-Bergamotene 21:607 [3-Bergamotene 26:459 Bergapten 20:497;22:522,539 from Limonia acidissima 20:497 Bergenin 13:660;23:536;27:395 from Ardisajaponica 13:660 regioselective hydroboration of 13:135 Berhamine 21:80 Bersama abyssinica 22:514 for epilepsy 22:514 exo-Bervicorffln 19:126 Bestatin 12:412,434,493 Beta mannosidase I 22:30 Beta vulgaris 15:3;20:721,731,740; 21:666 Betacyanin alkaloid 27:745 Betaenone B 4:601,602,621,17:475 Beta-eudesmol 24:883-887 potentiating effects on neuromuscular blocking action 24:883-887 Betagarin 22:458
Betaine 1:89,92,752,539 Betalaines 20:724,740 Betanidine 20:724-740 Betanine 20:724,731;26:305 Betavulgarin 22:458 Betavulgarosides from 21:666 Bethanecol 25:612 Betula davurica 26:895 Betula ermanii 26:895 Betula maximowicziana 26:895,899 Betula ovalifolia 26:899 Betula pendula 17:361,366 Betula platyphylla 17:361 Betula platyphylla var. japonica 26:255, 887,895,899 Betula sp. 17:358.361 ;26:894,905 Betulaceae 17:358,359,364,366;23:403 Betulatetraol 26:895 Betulifol A&B 26:568 Betulin 7:189,293;22:105;25:60 B etulinaldehyde-3 [3-yl-caffeate 30:646 2D NMR of 30:646 NOESY spectrum of 30:646 stereochemistry of 30:646 structure of 30:646 Betulinic acid 7:189,507;21:664; 25:59-61,66,541 ;26:813,814;28:17, 40,62;29:571,574 anti-microbial activity of 28:62 cytotoxic activity of 28:17 inhibition of Candida albicans aspartic protease 29:571 inhibition of HIV- 1 protease 29:571 Betulinic acid (lupane triterpene) 29:578 effects on aminopeptidase N 29:578 effects on HIV-1 protease 29:574 Betuloside 20:116 ent-Beyer- 15-en- 17,19-ol 30:714 structure of 30:714 Beyerane 15:252 Beyerane ent-3[3-Hydroxy- 15-beyeren2-one 29:100 activity in EBV assay system 29:100 BF3 rearrangement 5:782,783
104 BF3-mediated method 11:117 Bgt A 21:750-754 clinical trials of 21:754 pharmacological study of 21:748,752-754 of BgtA 21:750-754 B haringine 5:174,175 Bhesa paniculata 23:652 Bhilawainol 9:318 Bhimberine 9:170,172,173 BHT 25:792 5,5'-Bi(1,3-di-bromoazulene) 14:334 7,7'-Bi(3-bromoazulene)- 1,1' (7H,7H')dione 14:342 Bianco 29:487 valienamines synthesis by 29:487 9'-Bianthracene-10,10' (9H, 9'H) diones 11:125,1269 from 1,9-anthracenediols 11:125,126 8-Biapigenin 22:645 13,118-Biapigenin 22:662;30:618 structure of 30:618 Bicarbocyclic bridged systems 6:65-74 Bicarbocyclic fused system 6:5-38 Bicarbocyclic lactone 6:80 Bicuculline 21:69,733;22:26,27,508; 26:868 Bicyclic C-glycoside 30:470 cleavage of 30:470 Bicyclic cis-glycols 8:245,246 Bicyclic diterpene 8:220 Bicyclic diterpenoid glycosides 23:158 Bicyclic enone 14:678,679. taxodione from 14:678,679. from monocyclic ketones 10:311-313 Bicyclic gephyrotoxins (indolizidines) 11:244 Bicyclic keto ester 14:509 Bicyclic keto-acid 12:283 Bicyclic lactones 12:150 Bicyclic lupine alkaloids 27:267 Bicyclic olefin 11:371 Bicyclic phloeodictine B 28:688 antibacterial activity of 28:688 cytotoxic activity of 28:688 Bicyclic triene 6:79
Bicyclic [3-1actam 12:172,173 by Diels-Alder reaction 12:172,173 from cyclic imines carboxylic acid 12:117 from 2H-4H, 1,3-dioxin derivatives 12:160,161 synthesis of 12:172,173 Bicyclo [2.2.1] heptanes 8:415 synthesis of 8:415 Bicyclo [2.2.2] octane 6:70,71 (+)-sanadaol from 6:70,71 by double Michael addition 8:422 from Li-cyclohexadienolates 8:422 from c~,[3-unsaturated esters 8:422 synthesis of 8:412-422 B icyclo [2.2.2 ] octane ring 8:166 Bicyclo [3.2.1] octadione 8:161,162 synthesis of 8:161,162 Bicyclo [3.2.1] octane 8:420,421,40; 12:22 Bicyclo [3.2.1] octanone 6:78,79 Bicyclo [3.2.1 ] octenes 10:317,318 from bicyclo [3.3.0] octanones 10:317,318 Bicyclo [3.2.1] system 12:86 Bicyclo [3.2.1] hemithioacetal 8:205 Bicyclo [3.2.2] nonadienone 1:567 Bicyclo [3.2.2] piperazinedione 12:71 synthesis of 12:71 Bicyclo [3.2.2] system 12:85 Bicyclo [3.3.0] octane 10:315 spiro [4.5] decane from 10:315 cis-Bicyclo [3.3.0] octanes 13:4 Bicyclo [3.3.0] octanones 10:310,311, 317,318 Bicyclo [3.3.1] nonane 3:95; 6:65-69,224 conformation of 3:95 fragmentation of 3:74 Bicyclo [3.3.1] nonyl transition state 4:447;10:317,318 Bicyclo [4.2.2] mesylate 12:80 Bicyclo [4.2.2] ring system 12:64,65 Bicyclo [4.3.0] non- 1-en-3-one 10:310
105
Bicyclo [4.3.0] nonane 6:5-11;11:230 Bicyclo [4.3.1] dec-2-en-7-one 6:69 by Grob fragmentation 6:69 by intramolecular [2 + 2] photocycloaddition 6:69 synthesis of 6:69 Bicyclo [4.3.1] decane group 6:69-72 Bicyclo [4.3.1] decanone 6:70 nakafuran-9 from 6:70 synthesis by four carbon polar annulation 6:17,21 Bicyclo [4.4.0] decane 6:10,235 Bicyclo [4.4.1] undecane group 6:72-74 Bicyclo [4.4.1] undecanone 12:238,244 Bicyclo [5.1.0] ontanone 12:243 Bicyclo [5.2.2] piperazinedione 12:84, 85 synthesis of 12:84,85 Bicyclo [5.3.0] decane group 6:11,12 Bicyclo [5.3.1] undecane unit 12:179 Bicyclo [5.4.0] undecane group 6:29-33 Bicyclo [5.4.0] undecanone 12:249 Bicyclo [6.2.1] undecane 12:193 Bicyclo [6.3.0] undecane group 6:33-38 Bicyclo [6.3.0] undecane skeleton 1:568 Bicyclo [6.3.0] undecanone 6:36 from bicyclo [3.2.0] heptanone 6:36 poitediol from 6:36 Bicyclo [6.4.0] dodecyl structures 12:212 Bicyclo[2.2.2] ring system 28:363,370 construction of 28:363,370 Bicycloboranonane 13:1359Bicyclogermacrene 21:282;27:573 Bicyclohumulenone 2:278,279; 8:183-186 from Plagischila acanthophylla subsp, japonica 8:183 synthesis of 8:183-186 Bicyclomycin 12:63 antibiotic activity of 12:63 antimicrobial activity of 12:41 toxicity of 12:63 Bicyrtes ventralis 5:223,224,253 Biczamycin 12:63 Bidens aurea 25:614 Bidens campthotheca 29:682
Bidentatin 23:609,610 13C-NMR data of 23:610 IH-NMR data of 23:610 Bidesethylchloroquine 25:344 Bidesmosides 26:813 Bidesmosidic dammarame oligoglycosides 24:144 Bidesmosidic saponins 7:429,432; 24:133,134,144;27:664,675,671 sandrosaponin 27:671 Bidesmosidic triterpene saponin 24:149 Biellmann coupling 10:6-10 Biemma sp. 25:703 Biflavones 22:644;25:31,125,126,127, 539 amentoflavone 25:539 bilobetin 25:539 sequoiaflavone 25:540 ginkgentin 25:540 Biflavonoids 5:468,756-758;30:207 antinocicieptive effect of 30:207 Biflorin 3:450,451 from Eremophila latrobel 15:258 synthesis of 3:450,451 Biflustra perfragilis 17:81,89,91 ; 21:265 ;25:825 ;28:619-620 2-methyl-6,7-di(methylthio)-2Hisoquinoline-3,5,8-trione from 28:619 2-methyl-6-methylthio-2Hisoquinoline-3,5,8-trione from 28:619 Bifurcanol 20:26 Bifurcaria bifurcata 18:713 Bignoniaceae 7:406 Biguaiazulene 14:315,3193,3'5,5'-Biguaiazulene-3,3' (5 H, 5'H)-dione 14:320 Biguanides 21:459,488 Bigutol 21:205 BII cell bioassay 29:33-38 abutasterone activity in 29:34 24-epi-abutasterone activity in 29:36 ajugalactone activity in 29:34 ajugasterones activity in 29:34 amarasterone A activity in 29:34 atrotosterones activity in 29:34
106 bombycosterol activity in 29:34 calonysterone activity in 29:34 canescesterone activity in 29:34 castasterone activity in 29:34 24-epi-castasterone activity in 29:36 cheilanthone B activity in 29:34 cyasterones activity in 29:34 dacryhainansterone activity in 29:34 2-dansyl-20-hydroxyecdysone activity in 29:34 22-dehydro- 12-hydroxycyasterone activity in 29:34 22-dehydro- 12-hydroxynorsengosterone activity in 29:34 22- dehydr o- 20-iso-ecdysone activity in 29:35 3-dehydro-2-deoxyecdysone: (silenosterone) activity in 29:34 3-dehydro-2-deoxyecdysone 22acetate activity in 29:34
2-dehydro-3-epi-20-hydroxy-
ecdysone activity in 29:34 24(28)-dehydroamarasterone B activity in 29:34 24(28)-dehydromakisterone A activity in 29:35 25 (25 )- dehydropre cyasterone activity in 29:35 2-dehydroshidasterone-22glucoside activity in 29:35 14-dehydroshidasterone activity in 29:35 14-deoxy( 14 [3-H)-20-hydroxyecdysone activity in 29:35 3-deoxy- 113,20-dihydroxy ecdysone activity in 29:35 (20R)22-deoxy-20,21-deoxyecdysone activity in 29:35 2-de oxy- 20,26- dihydroxyecdysone activity in 29:35 22-deoxy-20-hydroxyecdysone (taxisterone) activity in 29:35 2-deoxy-20-hydroxyecdysone 22benzoate activity in 29:35 (14(x-H) 14-deoxy-25-hydroxydacryhainansterone activity in
29:35 2-deoxyecdysone-25-glucoside activity in 29:35 2-deoxyecdysone-3,22-diacetate activity in 29:35 25-deoxyecdysone activity in 29:35 (5 c~-H)2-deoxyintegristerone A activity in 29:35 5-deoxykaladasterone activity in 29:35 2-deoxypolypodine B 3-glucoside activity in 29:35 25,26-didehydroponasterone A activity in 29:35 2,22-dideoxy-20-hydroxyecdysone activityin 29:35 (5 [3-H)-dihydrorubrosterone 29:35 dihydrorubrosterone 17-acetate activity in 29:35 dihyropoststerone tribenzoate activity in 29:35 (22S)20-(2,2'-dimethylfuranyl) ecdysone activity in 29:35 ecdysone 2,3-acetonide activity in 29:36 ecdysone 22-hemisuccinate activity in 29:36 ecdysone 6-carboxymethyloxime activity in 29:36 3-epi-22-iso-ecdysone activity in 29:36 20-iso-22-epi-ecdysone activity in 29:37 25-fluoropolypodine B activity in 29:36 25-fluoroponasterone I3 activity in 29:36 for ecdysteroid-like activities 29:33 22,23-di-epi-geradiasterone activity in 29:35 geradiasterone activity in 29:36 28-homobrassinolide activity in 29:36 iso-homobrassinolide activity in 29:37
107
6f3-hydroxy-20-hydroxyecdysone activity in 29:36 513-hydroxy-25,26-didehydroponasterone A activity in 29:36 5 [3-hydroxyabutasterone activity in 29:36 25-hydroxyatrotosterone B activity in 29:36
3-epi-20-hydroxyecdysone
(coronatasterone) activity in 29:36 20-hydroxyecdysone 22-benzoate activity in 29:36 20-hydroxyecdysone 22hemisuccinate activity in 29:36 20-hydroxyecdysone 2-~-Dglucopyranoside activity in 29:36 20-hydroxyecdysone 3~-Dxylopyranoside activity in 29:36 20-hydroxyecdysone 6-carboxymethyloxime activity in 29:36 ( 5(x-H)20-hydroxyecdysone activity in 29:36
14-epi-20-hydroxyecdysone
activity in 29:36 26-hydroxypolypodine B activity in 29:36 5 [3-hydroxystachysterone C activity in 29:36 inokosterone 26-hemisuccinate integristerone A activity in 29:37 (25R/R) inokosterone-20hydroxy-ecdysone activity in 29:36 1-epi-integristerone A activity in 29:36 isostachysterone C activity in 29:37 kaladasterone activity in 29:37 5Gt-ketodiol activity in 29:37 limnantheoside C activity in 29:37 24-epi-makisterone A activity in 29:36 14-methyl- 12-en- 15,20-
dihydroxy-ecdysone activity in 29:37 14-methyl- 12-en-shidasterone activity in 29:37 24-methylecdysone (20-deoxymakisterone A) activity in 29:37 muristerone A activity in 29:37 29-norcyasterone activity in 29:37 29-norsengosterone activity in 29:37 paxillosterone 20,22-p-hydroxybenzylene acetal activity in 29:37 pinnatasterone activity in 29:37 podecdysone B activity in 29:37 polypodine B activity in 29:37 polyporusterone B activity in 29:37 ponasterone A 22-hemisuccinate activity in 29:37 ponasterone A 3[3-D-xylopyranoside activity in 29:37 ponasterone A 6-carboxymethyloxine activity in 29:37 ponasterone A dimer activity in 29:37 poststerone 20-dansylhydrazine activity in 29:37 punisterone activity in 29:37 rapisterones activity in 29:37 rubrosterone activity in 29:37 sengosterone activity in 29:37 shidasterone activity in 29:37 sidisterone activity in 29:37 silenoside A (20-hydroxyecdysone 22-galactoside) activity in 29:37 silenoside C (integristerone A 22galactoside) activity in 29:38 silenoside D (20-hydroxyecdysone3-galactoside) activity in 29:38 stachysterones activity in 29:38 213,313,20S,25-tetrahydroxy-25fluoro-5 [3-cholest-8,14-dien-6one activity in 29:38
108
2ot,3 ot,22S,25-tetrahydroxy-5acholestan-6-one activity in 29:38 213,3[3,6c~-trihydroxy-5[3cholestane activity in 29:38 turkesterone 11 c~-acetate activity in 29:38 turkesterone 11 ot-arachidate activity in 29:38 turkesterone 11 c~-butanoate activity in 29:38 turkesterone 11 c~-decanoate activity in 29:38 turkesterone 11 a-hexanoate activity in 29:38 turkesterone 11 c~-laurate activity in 29:38 turkesterone 11 a-myristate activity in 29:38 turkesterone-2,11 c~-diacetate activity in 29:38 turkesterone-2,22a-diacetate activity in 29:38 viticosterone E activity in 29:38 Bijvoet difference method 13:434 Bile alcohols 17:207,212 Billheimer method 9:464 Bimolecular [67t+47t] tropone diene 12:241 cycloaddition of 12:241 Bimolecular conjugate addition 24:768 Bimolecular cyclization 24:769 BINAL-H 16:377 SBinandkatsuim A 20:276 BINAP 13:72 (S)-BINAP 19:29 BINAP-Ru-catalyst 4:439 in asymmetric hydrogenation 4:439 Binary indole alkaloids 5:140-151 Binatriol 30:710 structure of 30:710 Binding assay 30:494 of calf-thymus vitamin D receptor 30:494 Binding bioactivity 30:813 of [Tyr)Me)2-Phe] peptides 30:813
of d-Tyr(Me)2-d-Phe-G-V-VNH2 30:813 of d-Tyr(Me)2-d-Phe-NH2 30:813 of d-Tyr(Me)2-Phe-G-V-V-NH2 30:813 of d-Tyr(Me)2-Phe-NH2 30:813 of Tyr(Me)2-d-Phe-G-V-V-NH2 30:813 of Tyr(Me)2-d-Phe-NH2 30:813 of Tyr(Me)2-Phe-G-V-V-NH2 30:813 of Tyr(Me)2-Phe-NH2 30:813 Binding pocket 27:33 Bioactive 3-deoxy-ulosonic acids 30:419 recent advances in 30:419 Bioactive compounds 24:954-956; 28:3,4,9,16,22 from Broussonetia genus 28:3 from Broussonetia kazinoki 28:4,9 from Broussonetia papyrifera 28:16,22 of EMIBD 24:954-956 Bioactive constituents 23:552;30:559 of genus Hernandia 30:559 of monotoideae 23:552 Bioactive diterpenes 24:175-213 Bioactive marine natural products 21:293 biosynthesis of 21:293 Bioactive metabolites 21:364;23:185 from Indo-Pacific marine invertebrates 21:251 from soil-borne fungi 21:181 of symbiotic marine microorganisms 23:185 structure-activity relationships of 21:251 Bioactive monoterpenoids 28:426 carvacrol as 28:426 carvomenthenol as 28:426 carvone as 28:426 citronellol as 28:426 eugenol as 28:426 geraniol as 28:426 perillyl alcohol as 28:426 4-terpineol as 28:426
109
thymol as 28:426 Bioactive natural products 23:488 Chinese medicinal plants 21:729 from bioactive natural products 21:729 from Chinese medicinal plants 21:729 Bioactive oleanane glucurnoides 25:89 Bioactive peptide 25:367 Bioactive saponins 21:633 bioactivity of 21:744 from plants 21:633 licochalcone A 21:744 Bioactive secondary metabolites 23:185-231 from Okinawan sponges 23:185-231 from tunicates 23:185-231 Bioactive terpenes 24:175-213;30:635 from celastraceae 30:635 from Wieland Miescher ketone 24:175-213 Bioactivity 21:744;23:335;24:933972;25:668;26:909,911-914,926; 27:348;30:233,516,520 8'-hydroxyabscisic acid 27:349 bioactivity of 27:348 of 8'-hydroxyabscisic acid 27:349 of carotenoids 30:516,520 of cocumarins 23:335 of EMIBD 24:954-956 of endophytic fungi 24:933-972 of HIRE 24:951-954 of labiatae flavonoids 30:233 oflicochalcone A 21:744 of nitric oxide 26:926 of phenolic compounds 25:668 Bioantimutagenic 21:641 Bioassay-directed fractionation 30:157, 591 of Ozoroa insignis 30:157 use of chromatographic techniques in 30:591 Bioassays 24:863-869;30:801 allelopathy 24:867 anti-feedant 24:866 anti-fungal green house 24:864 anti-inflammatory 24:869
anti-microbial 24:863,864 antioxidant 24:868 brine shrimp 24:864,865 caterpillar data 24:866 corn earworm 24:865 cytotoxicity 24:867 forest Tent caterpillar 24:865 Gypsy moth 24:865 herbicidal 24:867 insecticidal 24:866 mosquitocidal 24:864 neuraticidal 24:866,867 statistical analysis of 24:866 tobacco hornworm 24:865 topoisomerase inhibitory 24:867, 868 Bioautographic methods 21:257 Bioautographic TLC assays 26:255 Bioavailability 23:776;27:312,314 of nutrients 27:312,314 of phenolic antioxidants 23:746, 775 Biochanin A 22:446 Biochemical assays 30:226 activity of natural polyphenols in 30:226 Biochemical studies 27:393 of natural products 27:393 Biocidal activity 21:598 Biocides 25:668 Biocontrol activity 21:187 Biocontrol agents 21:181 Bioconversion 17:470 using Morus alba cell 17:470 Biofilms 17:100 Bioflavours 25:125,128,129,294,300, 329,401,659,661,662 de novo synthesis of 25:128,129, 294,300,329,401,659,661,662 Biogeneration 13:295-345 of flavors 13:295-345 Biogenesis 23:204,211,253,255,395453 ;26:141,142,313,314,405,465, 552,1054;27:515 for Nb-C(21) secocuran alkaloids 26:1054 of diterpenes 26:465 of ecteinascidins 23:253,255
110 of ellagitannin oligomers 23:395-453 of F r a x i n u s ornus 26:313,314 of manzamenone K 23:204,211 of sclareol 26:405 of secologanin type alkaloids 26:142 of some iridoids 26:141 of swainsonine 27:515 of the resveratrol oligomers 26:552 total synthesis of 24:588-605, 656 Biogenetic aspects 21:129 kopsirachin as 21:129 Biogenetic precursor 16:301 ;30:622 of allamandicin 16:301 of plumericin 16:301 of xanthones 30:622 Biogenic amines 15:328 Bioinsecticides 15:381 Bioisosteric replacement 21:257 Biological action 24:875 as anti-angiogenesis 24:875 as anti-hyperglycemic 24:875 as anti-inflammation 24:875 as anti-proliferation 24:875 in blood glucose regulation 24:875 in blood vessel relaxation 24:875 in cardiotonicity 24:875 in neuromuscular blocking 24:875 in smooth muscle relaxation 24:875 Biological activities 21:132,148,162, 223,236,23 8,263,265,269,284,297, 366,388,390,410,419,421,431,571, 578,591,598,601,603,620,694;23:63, 93,95,108,111,129,126,107-152,153, 158,179,267,271,285,395-453, 455-485,491,497,642-643 ;739;24:25, 353-376;799,845;27:178,185-225, 332,377,431,421,443,659693,778, 801,924;28:109,212,228,229,340; 29:743 ;30:4,26,172,175,200,224, 303,310,395,404,483,484,485,495, 496,497,499,562,588,603,637,831, 840,843
acaricidal 24:799 allelopathic 24:845 anti-bacterial 24:25 antibiotic 24:799 anti-feedant 24:845 anti-fungal 24:25,799 anti-inflammatory 24:799 antimalarial 30:561 anti-microbial 24:845 anti-oxidant 24:845 antioxidant 30:561 antiplatelet aggregation 30:560 anti-secretory 24:799 anti-serotonergic 24:799 anti-tumor 24:845 chirality in 7:3-28 choleretic 24:799 cytotoxic 24:799,845 cytotoxic 30:560,561 Decumbenine B 21:735 herbicidal 24:799 H e r n a n d i a species 30:588 in black-sugar 27:409,410 in fat cell 27:393 in human osteosarcoma ~ 30:497 m human osteosarcoma 2 30:497 m red wine 27:430 zn vivo 30:499 inhibition of enzyme 24:845 insecticidal 24:25,799,845 isolation of 4:243 molluscicidal 24:799 of(-)-selin-11-en-4c~-ol 14:450, 451 of (+)-caffeic acid 27:421 of (+)-chlorogenic acid 27:421 of (+)-compactin 11:335,336 of (+)-mevinolin 11:335,336 of (EFEa) 30:831 of[3-glucans 23:107,111,115,135 of 14et-hydroxy-MFA 28:340 of 1-methoxyficifolinol 28:229 of 1-methoxyphaseollidin 28:229 of lcc,25-(OH)2D 30:495 of 1et,25(OH)2D analogues 30:495 of la,25(OH)2D3 30:496 of lot,25(OH)zD4 30:499
111 of 3'-(7,7-dimethylallyl)kievitone 28:228 of 3-hydroxyglabrol 28:228 of 3-hydroxyparatocharpin C g 28:228 of 3-O-methylgancaonin P 28:229 of 4'-O-methylglabridin 28:229 of 6-prenyleriodictyol 28:229 of 6-prenylnaringenin 28:229 of 8-(y,y-dimethylallyl)wighteone 28:228 of 8-prenyleriodictyol 28:229 of abscisic acid 27:331,352 of acetyl-N-Ser-Asp-Lys-Pro 27:806 of agrimoniin 23:398 of agrimoniin 23:398 ofalbanin D 28:229 ofalbanin F 28:230 ofalbanol A 28:230 ofalbanol B 28:229 of alvaxanthone 28:229 of amicoumacins 15:410-412 of Angelica shikokiana 27:429 ofangustone B 28:228 ofantlarone B 28:229 ofantlarone F 28:229 ofantlarone G 28:229 ofantaarone H 28:229 ofannarone I 28:229 ofannarone J 28:229 of Artemisia montana extracts 27:420 of Artemisiae herba 27:413 of artobiloxanthone 28:229 ofartonin E 28:229 of astragalus L. genus 27:443 of avermectins 12:7-9 ofbaciphelacin 15:409,410 of baicalein 27:433,435 of balanol 27:869 of bavachalcone 28:228 of Benzo [c]phenanthridine alkaloids (QBA) 27:819 ofbenzoxazinoids 27:211 ofbenzoxazinones 27:185-225 of bis-indolyl maleimides 12:384-399,133,91
of bombesin 27:797 of bombsin 27:797 ofbroussochalcone B 28:228 ofbroussoflavonol B 28:229 ofbroussoflavonol C 28:229 ofbroussoflavonol E 28:230 of Bupleurum rigidum 27:693 ofBupleurum rigidum L. 27:659 of capsaicin 30:200 of chitosan 27:404 of cholesterol oxides 24:351-398 ofcudraphenone B 28:230 ofcudraphenone D 28:230 of cycloartobiloxanthone 28:230 ofdecumbenine B 21:735 ofdehydroglyasperin C 28:228 of discodermolide 30:4 of dynorphins 27:801 of echinatin 28:228 of edudiol 28:228 of EFE 30:840 of endorphins 27:801 of endotoxin-induced 27:435 ofenkephalins 27:801 oferythrinin B 28:229 of erythromycin 13:155-185 ofEscherichia coli 30:843 of essential oil 21:571 of essential oils 21:571-580,573 offlavonoids 23:739;27:431 of formaononetin 28:228 of free fatty acid 27:404 of fungal [3-glucans 23:108,111, 126 ofgancaoinm S 28:228 of gancaonm C 28:228 of gancaonm E 28:228 of gancaonm G 28:228 of gancaonm H 28:228 of gancaonln I 28:228 of gancaonln O 28:228 of gancaonan P 28:228 of gancaonan Q 28:228 of gancaonm R 28:228 of gancaonm U 28:228 of gancaonm V 28:228 of gancaonln Y 28:228 of garlic 23:468 of Geranii herba 27:413,415
112 of Ginkgo biloba 30:172 ofginsenoside Rgl 27:424 of glabranin 28:228 of glabranine 28:228 of glabrene 28:228 of glabridin 28:228 of glabrocoumarone A 28:229 of glabrol 28:228 of glisoflavanone 28:228 of [3-glucosidases 27:778 ofglyasperin A 28:228 ofglyasperin B 28:228 ofglyasperin C 28:228 ofglyasperin D 28:228 ofglyasperin J 28:228 ofglyasperin K 28:228 of glycycoumarin 28:228 ofglycyrdione A 28:228 of glycyrin 28:228 of glycyrol 28:228 ofglyinflanin A 28:228 of green tea 27:417,420 of Hernandia nymphaeifolia 30:562 of Hernandia species 30:562 of Hernandia voyronii 30:562 of heterophyllin 28:230 of hispaglabridin A 28:228 of hyperlipdaemia 27:405 of indolo [2,3-a] carbazole alkaloids 12:384-399 ofintermedeol 14:450,451 of isoalvaxanthone 28:230 of isoderrone 28:228 of isoglycyrol 28:228 of isoliquiritigenin 28:228 of ivermectin 12:8,9 ofkanzonol B 28:229 ofkanzonol G 28:229 ofkanzonol H 28:229 ofkanzonol P 28:229 ofkanzonol R 28:229 ofkanzonol S 28:229 ofkanzonol U 28:229 ofkanzonol V 28:229 ofkanzonol W 28:229 ofkanzonol X 28:229 ofkanzonol Y 28:229 ofkazinol B 28:230
ofkazinol E 28:230 ofkazinol F 28:230 ofkazinol N 28:230 of KB-1 28:229 of KB-3 28:229 of kumatakenin 28:229 ofkuwanon 28:212 ofkuwanon C 28:230 ofkuwanon G 28:230 ofkuwanon H 28:212 ofkuwanon M 28:212 ofkuwanon R 28:230 of ot-lapachone 29:743 of[3-1apachone 29:743;30:310 oflicochalcone A 28:229 oflicochalcone B 28:229 of licoflavonol 28:229 of licoisoflavanone 28:229 oflicoisoflavone A 28:229 oflicoisoflavone B 28:229 of licorice 27:425 of licoricidin 28:229 of licoricone 28:229 oflicorisoflavan A 28:229 of lipogenesis 27:393 of lipolysis 27:393 of macarangaflavanone B 28:229 of medicarpin 28:229 of medicinal plants 27:393,405 of microcystins 20:896,897 of monoterpenoid enantiomers 27:377 of montanin C 23:643 ofmoracein B 28:230 ofmoracin C 28:230 of morusin 28:212,230 of morusinol 28:230 of mulberrin 28:230 of mulberrochromene 28:230 of mulberrofuran B 28:230 of mulberrofuran G 28:212,230 of naringenin 28:229 of natural products 7:3-29; 27:393,405 of natural steroids 30:485 ofneointermedeol 14:450,451 of nocamycin 14:110 of nodularins 20:896,897 of non-sugar fraction 27:409,410
113 of norartocarpetin 28:230 of oligomeric compound 27:778 of Oolong tea 27:401 of opioid peptides 27:801 of organosulfar compounds 23:455-485 of organosulfur compounds 23:468 of oxydihydromorusin 28:230 ofparatocarpin L 28:229 ofphaseoluteone 28:229 of PI turnover inhibitors 15:461, 462 ofpinocembrin 28:229 of pironetin 30:26 of plasma glucose 27:412 ofpolyene macrolides 6:261 ofPolygonum sp. 27:405 of polyphenols 30:224 ofpolysaccharide (PS) 30:395 of Pseudopterogorgia sp 23:179 of pseudopterosins 23:154,158 of pyranocoumarin 27:429 of quassinoids 23:285-333 of quinones 30:303 of resorcinolic lipids 30:175 of resveratrol 27:430 ofrifamycin B 23:93 ofrifamycin P 23:95 ofrifamycin S 23:94 of saikosaponins 27:693 ofsanggenol C 28:230 ofsanggenol M 28:230 of sanggenon A 28:212,230 ofsanggenon B 28:230 ofsanggenon C 28:212,230 of sanggenon D 28:212 ofsanggenon M 28:230 of saponin 27:859 of Scutellariae radix 27:431 of self-inhibitors 9:222,238 ofsemilicoisoflavone B 28:229 of serum TC 27:420 of serum transaminase 27:415, 417,420,421 of serum triglyceride 27:404 of shinpterocarpin 28:229 ofsigmoidin A 28:229 ofsigmoidin B 28:229
ofsorocein F 28:230 of soyasaponins 27:399 ofspatane diterpenoids 6:39 of spatol 6:39 of sphingolipids 18:459,460 of Spirulina platensis 30:404 of staturosporine 12:399 ofstilbene derivatives 27:405, 409 of streptolydigin 14:108,109 of tannic acid 23:412 of tannin 23:442;27:413,416 of taxanes 11:4-6 of taxodione 14:667 oftenuifolin B 28:229 of tetracyclic pyridoacridine alkaloids 23:271 of tetrahydro-13-carbolines 23:267 of tetramic acid 14:107-110 of tetramic acid-containing compounds 28:109 ofteucjaponin A 23:642 ofteucjaponin B 23:643 of topozolin 28:229 of triterpenes 30:637 of tyrosine kinase inhibitors 15:447,449 of vitamin D analogues 30:485 of vitamin D 2 30:483,484 of vitamin D3 30:483,484 of vitamin D4 30:483,484 of vitamin D5 30:483,484 of vitamin D6 30:483,484 of vitamin D7 30:483,484 of wighteone 28:229 of xenocoumacins 15:408,409 spasmogenic 24:799 spasmolytic 24:799;30:561 stimulatory 24:845 trypanosomal 24:799 Biological activity alteration 24:897 by processing 24:897 Biological behaviour 21:161,169 of galactose prodrugs 21:161 of glucuronic prodrugs 21:169 Biological control 21:182 of soil-born phytopathogens 21:182
114
Biological control fungi 21:187 antifungal metabolities from 21:187 biological behaviour of 21:161 galactose prodrugs 21:161 glucuronic prodrugs 21:169 Biological Diels-Alder reaction 17:451 Biological effects 21:501,524 Biological evaluation 23:591-648 of Genus teucrium 23:591-648 Biological processes 30:420 ofulosonic acids 30:420 Biological properties 10:241-302;23:93; 28:518,519 of ansamycin antibiotic 23:93 of didemnins 10:241-302 of lipid A 28:519 oflipo-CCK 18:857-863 of lipo-gastrin 18:857-863 Biological raw materials 17:601 Biological response 23:12 Biological response modifiers (BRMs) 25:431,434,452-455 Biological role 27:224,225;30:422 of benzoxazinone acetal glucosides 27:224,225 ofbenzoxazinones 27:185-225 of 3-deoxy ulosonic acids 30:422 Biological screening 29:366 allocolchicinoid synthesis for 29:364 Biological significance 24:369 of cholesterol variation number (CVN) 24:351,368,369 biological significance of 24:369 Biological studies 28:35;30:561 of genus Hernandia 30:561 on Licania genus 28:35 Biologically active constituents 17:153; 23:662 of celastraceae 23:662 Biologically active diterpenoids 21:689 from Scoparia dulcis 21:689 Biologically active glycolopoprotein complex (G-90) 30:485,826 species of 30:826 Biologically active metabolites 23:649-738 of celastraceae 23:649-738
Biologically active precursor 23:63 ofdamavaricin D 23:63 of damavaricin C 23:63 Biology 21:364 of marine isocyanides 21:364 Biomedicine 30:827 Biomethylation 9:47 Biomimetic cationic polyene cyclization 12:456 Biomimetic cyclization 14:681-684 ofallylic alcohol 14:681-684 Biomimetic olefin cyclization 1:671-673 Biomimetic polyene cyclizations 7:131 Biomimetic synthesis 24:743 Biomineralization 25:335 of heme 25:334 of hemozoin 25:360 Biomphalaria glabrata 7:432435 ;23:537,849;25:785 Bio-organic chemistry 9:431-445 of ansamycin 9:431-445 of antibiotics 9:431-445 of mitomycin 9:431-445 Biopholaria glabrata 25:792 Biophysical studies 27:334 ofabscisic acid 27:334 Biopolymers 17:481 Bioquercetin 7:226 Biorational plant protectants 21:109 alkaloids as 21:109 Bioregulators 2:377-386 studies with 2:377-386 chiral synthesis of 6:537-566 Biosilica 25:717 BIOSIS 19:758 Biosynthesis 21:293;23:51,79;27:321; 29:295 abscisic aldehyde in 27:321 by Read and Vining 29:295 in Clitocybe subilludens 29:296 in Peniophora sanguinea 29:298 in Phleba strigosozonata 29:296 of ansamycins 23:51,79 of ascocorynin 29:296 of atromentin 29:296 of bioactive marine natural
115 products 21:293 of deoxylapachol 29:736 of ecdysteroids 29:5 of gingerol 23:848 ofisocyanide group 21:349 of isoprenyl- 1,4-naphthoquinones 29:735 oflapachol 29:734 oflawsone 29:736 of lignans 24:742-744 of macrolide antibiotics 29:322 of manool 25:253,254,259 of melanin 26:1019 of menaquinone- 1 29:736 of nitrogen compounds 29:328 of ortho-terphenylquinone phlebiarubrone 29:296 of polyhydroxy-p-terphenyl 29:295-297 of scopadulan-type diterpenoids 21:721-723 ofstreptovaricin D 23:64 of terphenyllin 29:296 of tetracyclines 29:312 ofthelephoric acid 29:296 of triterpenoids 22:97 of volucrisporin 29:295 of xylerithrin 29:298 zeaxanthin in 27:321 Biosynthetic pathways 24:846,847 for production of natural products 24:846,847 Biosynthetic studies 23:266,260 of[3-carbolines 23:260,266 Biota orientalis 25:275;29:102 Biotechnology 13:296,297,299 Biotic stress 23:741 Biotinylated gastrin 18:920 Biotinylated peptides 18:919 Biotoxicity 21:596 Biotransformation 23:3,5,42;24:74-76, 309-318 of benzosampangine 23:3,5,42 of cis-6fl-sesquiterpene 24:74,75 of 6fl-eudesmanolioes 24:76 Biotransformation rates 27:377 Bipendensin 9:256 from Afzelia bipendensis 9:256 Biperezone 20:273
Biphenyl ether,4,4'-diallyl-2,3'dihydroxybiphenyl ether 24:861 anti-fungal activity of 24:861 Biphenyls 23:342 3,3'-Biplumbagin 2:212,214,5:754 ~H-NMR spectrum of 2:227 Bipolar disorder 30:369 effect of circadian activity on 30:369 Bipolaris sorokiniana 4:647;9:238; 21:196,199 Bipolaris zeicola 27:498 2,3'-Bipyridyl alkaloids 5:753 Birch reduction 11:286 of o-toluidine 11:286 of 6-methoxy-l-tetralone 12:235 of 4-methoxytoluene 12:22-24 ofp-cresyl methyl ether 6:83,84 BIRD sequence 9:97,98 12,12'-Bis (11-hydroxycoronaridyl) 5:129 B is (6-formyl-4-hydroxy-2-(2'-n'pentytoxazol-4'-yl)-4-pyridon-3-yl] 25:841 4-Bis (8-hydroxyquinolin-4-yl)butyrolactone 5:7533, (3R,4R)-3,4-bis (Benzyloxy) succinic anhydride 12:295 Bis (di-isoamyl) borane reduction 9:366 Bis (EDTA-DISTAMYCIN) phenoxazone 5:570 Bis (trimethylsilyl) ethylene glycol 1,3-dioxolane formation 1:584 Bis (trimethylsilyl)- 1,2-ethanedithiol 1,3-dithiolanes 1:584 reaction with aldehydes 1:584 reaction with ketones 1:584 Bis allylic bromide 8:16 Bis indole alkaloids 2:370371,387,389, 390,394,398 3'-Bis(2-cyanoethoxy) phosphoryl group 14:291,292 branched RNA from 14:291,292 2'-Bis(2-cyanoethoxy) phosphorylation 14:299,302 Bis-(3,7-diisopropyl- 1-azulenyl) ketone 14:340 Bis(bibenzyls) 2:103, 2:113
116 2,5-Bis(dimethylamino) benzoquinone 13:434 Bis-(EDTA-distamycin) fumaramide 5:569
[Bis(trifluoroacetoxy)iodo]benzene
30:439 as reagent 30:439 2,4-Bis-(trimethylsiloxy)-furan 13:451 Bis(trimethylsilyl) acetylenes 14:473 Bis(trimethylsilyl) butadiyne 14:473 Bis- 1-oxaquinolizidne macrocycles 24:606 structures of 24:606-609 11(15---~1), 1 l(10--~9)Bisabeo taxane 20:80,107 2,10-Bisaboladie- 1-one 26:861 Bisabolane 25:848 Bisabolane xanthorrhizol 29:87 activity in COX assaysystem 29:87 activity in iNOS assay system 29:87 Bisabolane: ar-turmerone 29:87 activity in COX assay system 29:87 activity in iNOS assay system 29:87 Bisabolane: [3-turmerone 29:87 activity in COX assay system 29:87 activity in iNOS assay system 29:87 Bisabolanes 23:830;26:457;27:13 highly sweet compound from 27:13 R-c~-Bisabolene 16:232 6-Bisabolene 17:609 Bisabolene 26:861 Bisabolene diterpenes 15:255-257 Bisabolene isoprenologues 15:277 Bisabolol oxide derivatives 7:218 [3-Bisabolon 20:6 1-Bisabolones 8:39-44,46,48 Bisabulene sesquiterpenes 23:164 Bisacnadinine 20:265 Bisacurol 23:830 Bisacurone 23:830 Bisacurone A 23:830
Bisacurone B 23:830 Bisanhydrobacterioruberin 20:601 Bisaryltetrahydrofurans 17:325 Bisbenzofuranoid terphenyls 29:284 as PEP inhibitors 29:284 in antimicrobial assays 29:284 Bisbenzofuranoid terphenyls 29:284 p-terphenyl benzobisbenzofurans corticin A as 29:285 m-terphenyl corticin C as 29:285 meta-terphenyl kynapcin-9 as 29:284 Bisbenzylisoquinoline 22:22;26:824, 825,826,827 Bisbenzylisoquinoline alkaloids 6:472, 657,525;25:530;30:584 berbamin 25:530 decricine 25:530 isochondroendrine 25:530 macoline 25:530 oxycanthine 25:530 rodiasine 25:530 tubacurarine 25:530 Bisbenzyltetrahydrofurans 17:330 Bisbrusatolyl esters 7:383,384 Bisbrusatolylsebacate 23:305 Bisbrusatolylsuccinate 23:305 Bisbrusatoryladipate 23:305 Biscarbamate 22:220 Bischler-Napieralski condensation 14:763 isokomarovine from 14:763 komarovidine from 14:763 of tryptamine 14:763 with quinoline-5-carboxylic acid 14:763 Bischler-Napieralski cyclization 4:20, 23,444 Bischler-Napieralski reaction 3:460, 93,633,790;8:291 Bisconicasterone 26:1177 Biscumol 23:830 Biscyanopropylhenyl siloxane 9:456 Biscyclolobin 20:283 Bisdehydroneotuberostemonine 21:770 Bisdehydrostemoninine 21:770 Bisdehydrotuberostemonine 21:770 6,10-Bisdeoxyaucubin 7:465,466,474, 476,477
117 Bisdesmosyl saponin 25:108,120
Bis-Fischer indolization 12:376,377 Bishofianin 23:406 Bishopamholide 7:234 Bishopsolicepolide 7:234 Bisindoles 29:225 arcyriacyanin A as 29:226 arcyriaflavin A as 29:225 arcyriaoxocin A as 29:226 arcyriarubin A as 29:225 structures of 29:226 Bisindole-type alkaloids 5:121,129 aceedinine 5:112 aceedinisine 5:112 biomimetic synthesis of 13:404-407 bis (11-hydroxycoronaridyl) 5:121,129 bonafousine 5:122 capuvosine 5:114 conodurine 5:116 16-decarbomethoxy- 19'20'dihydrovoacamine 5:114 16-decarbomethoxyvoacamine 5:114 14,15-dehydrotetrastachyne 12,12'-5:121 dehydroxycapuvosine 5:114 N4-demethylcapuvosine 5:114 11-demethylconoduramine 5:115 N4-demethyltabernamine 5:113 N4'-demethylvoacamine 5:115 20R- 1,2-dihydrocapuvosidine 5:114 20S- 1,2-dihydrocapuvosidine 5:114 20'S- 19',20'-dihydrotabernamine 5:114 divaricatine 5:118 ervafolene 5:120 ervafolidene 5:121 3-epi-ervafolidene 5:121 (3R)-ervafolidine 5:120 3-epi-ervafolidine 5:121 ervafoline 5:120 ervahanine A 5:115 ervahanine B 5:115 ervahanine C 5:115 gabunamine 5:115
gabunine 5:115 hazuntiphylline 5:120,121 3-R/S-hydroxy- 16-decarbomethoxy conodurine 5:115
19'S-hydroxy-3-epi-ervafolidine 5:121
3-R/S-hydroxyconoduramine 5:117
3-R/S-hydroxyconodurine 5:118 19'-hydroxyervafolene 5:120 19'-R-hydroxyervafolidine 5:121 19'-hydroxyervafoline 5:121
3'-R/S-hydroxy-N4-demethylervahanine A 5:115
3'-R/S-hydroxy-N4-demethylervahanine B 5:115
3'-R/S-hydrox y-N4-demethyltabemamine 5:114,124 19R-hydroxytabernaelegantine B 5:117
3'-R/S-hydroxytabernaelegantine B 5:117
3'-R/S-hydroxytabernamine 5:114
3'-3R/S-hydrox yvoacamine 5:117 isobonafousine 5:122 isocapuvosine 5:114 3-methoxyltabemacelegantine C 5:118 moinogagaine 5:119 3-oxo-conodurine 5:116 3-(2-oxopropyl)-conodurine 5:18 pandicine 5:118 pseudo-vobparicine 5:119 tabernaelegantinine A-D 5:175, 118,129 tetrastachyne 5:121 tetrastachynine 5:121 voacamidine 5:116 voacamine 5:116 voacamine-N4-oxide 5:119 vobtusine 5:120 Bisindolymaleimides 29:230 cell-cycle checkpoint inhibition by 29:230 cyclin-dependent kinase (CDK) inhibition by 29:230 protein kinase C inhibition by
118 29:230 rebeccamycin as 29:230 staurosporine as 29:230 topoisomerase I mediated DNA cleavage 29:230 Bisindolymaleimides 29:230 rebeccamycin as 29:230 staurosporine as 29:230 Bisiridoids 7:443 Bisisodiospyrin 20:276 Bisisoquinoline alkaloids 21:79 (-)-5,10-Bisisothiocyanakalihinol G 25:857 a, c0-Bisisothiocyanates 25:857 3,3'-Bisjuglone 20:276 Bisketene 4:349 Bismuth citrate 25:617 15,16-Bisnor- 13-acetoxylabda8(17), 11E-dien- 19-oic acid 29:101 activity in EBV bioassay system 29:101 15,16-Bisnor- 13-oxolabda-8(17)-en- 19oic acid 29:102 activity in EBV bioassay system 29:102 14,15-Bisnor-8ot-hydroxylabd-11E-en13-one 29:101 activity in EBV bioassay system 29:101 26,27-Bisnorbrassinolide 19:263-265 Bisnordihydrotoxiferine 26:1050,1051 Bisnortoxiferine 21:79 26,27-Bisnortyphasterol 19:268 2',4'-Bis-O-(2-methoxy ethoxy methyl)4-O-methyl-7,8-dihydronogarene 14:87 (+)-2',4'-Bis- O-(2-methoxy ethoxymethyl)-7,8-dihydronogarene 14:83,87 (+)-2',4'-Bis-O-(2-methoxy ethoxymethyl)-7-con-O-methylnogarol 14:88 Bisobolane skeleton 25:849 2',3'-Bisphosphoramidite 14:293 2,3'-Bisphosphorylated ribonucleoside 14:284-290 Bis-quinoline antimalarial compounds 25:346
Bis-quinolines 25:345 Bisquinolizidine alkaloid 27:264 13C-NMR of 27:264 IH-NMR of 27:264 Bis-quinolizidnie macrocycles 24:606 structures of 24:606-609 total synthesis of 24:610,611 Bis-seco-dehydrocyclopiazonic acid 28:119 Bisstrictidine 5:140,141 7,7-Bistaxodione 20:678 from Salvia montbretii 20:678 Bistetrahydrofuran 10:439,440 Bistheonellasterone 26:1176,1177 Bis-THF acetogenins 17:270 Bis-THF structures 17:258 Bis-thiazole metabolite 25:790 Bistratamide 10:243 Bistratamide D 25:903 Bistratenes A,B 10:243 Bisubstrate mimetics 24:415 Bivittoside A 7:270,271 Bivittoside A,B,C and D 1:270;15:91 Bivittoside C 28:589,590 structure of 28:590 Bixa orellana 20:721,733,59 Bixin 30:528,529 structure of 30:529 Blaberus discoidalis 9:488,489 Blaberus gigantus 22:381 Black mycelium 21:204 Black vomit 1:679,680 Blackcurrant oil 13:659 Black-sugar 27:409,410 biological activity of 27:409,410 Blasticidin 23:343;28:127 as antibiotic 28:127 Blasticidin H 4:241,243 Blasticidin S 4:242,243 absolute configuration 4:242,243 biosynthesis of 4:243 synthesis of 4:243 Blastobacter sp. 25:841 Blastocladiella emersonii 5:276 Blastocrithidia 2:298 Blastogensis 26:217 inhibitory activity on 26:217 Blastomyces dermatiditis 5:307;22:248 Blastomyces sp. 5:325,328
119 Blastomycosis 2:422;22:60 Blatella germanica 6:53;9:488,489; 27:384 Blatellastanoside 25:757,795 Blatta orientalis 9:488,489 Blechert's construction 12:195 Bledius mandibularis 4:494 Bledius spectabilis 4:494 Bleekeria vitiensis 1:125 Bleekerine 1:125,158 oxidation 1:125,158 Bleomycins 16:573;20:458;24:547,548 antiviral microbial-derived compound 24:547,548 Blepharis edulis 27:188,191,193 Blepharispenum zangubaricum 25:251 Blepharocalyxin A 23:805 Blepharocalyxin B 23:85 Blestrin 20:280 Blighia welwitschii 15:205 Block-type polysaccharides 14:248 Blood chylomicron 30:79 obesity induction 30:79 Blood coagulation 21:670;30:70 role of serine protease in 30:70 role ofthrombin in 30:70 Blood coagulation activity 21:670 Blood glucose 30:58 effect of Ganoderman lucidum 30:58 elevation of 30:58 Blood glucose regulation 24:875 as biological action 24:875 Blood glucose regulatory action 24:875-925 of Kampo medicines 24:875-926 Blood platelet-aggregation 16:373 Blood pressure activity 21:670 Blood schizontocidal activity 22:152 Blood thrombocytopenia 26:265 Blood vessel contraction 24:875-925 of Kampo medicines 24:875-926 Blood vessel relaxation 24:875-925 as biological action 24:875 of Kampo medicines 24:875-926 Blood vessels 30:410 Blood-brain-barrier (BBB) 786,800,813 Blood-high-viscosity-syndrome 30:839 treatment of 30:839
Bloom-forming cyanobacteria 26:352 Anabaena 26:352 Aphanizomenon 26:352 Cylindrospermopsis 26:352 Lyngbya 26:352 Microcystis 26:352 Nodularia 26:352 Nostoc 26:352 Oscillatoria (Planktothrix) 26:352 Umezakia 26:352 Blossom oils 25:165;27:373 Blue cheese flavour 25:129 Blue crustacyanin 30:533 Blue oxonium ions 30:531,532 formation of 30:531 via cyclic hemiketals 30:532 Blue-green algae 21:303,304,367,415 Blumea malcomii 5:678 Blumenkrantz method 25:435 Bmy-41950 12:366,368 from Streptomyces staurosporeus 12:366,368 Boariol 18:743,752 Boat-boat inversion potential 27:343 of 1,4-cyclohexadiene 27:343 Bobolstemma paniculatum 21:665,674 N-BOC (3R,4S)-statine 12:480 from (3R,4S)-statine 12:480 BOC anhydride method 12:121 BOC functionality 4:91,92 deblocking with TMSOT 4:91,92 N-BOC-l-allo-threonine methyl ester 12:430 N-BOC-2-amino alcohol 12:480 (R)-N-BOC-2-amino alcohols 12:435, 436 with thionyl chloride 12:435,436 N-Boc-3-methyl-3-pyrroline-2-one 21:418 (S)-N-BOC-amino alcohols 12:481 O-N-BOC-amino benzaldehyde 18:163 N-Boc-ampullicin 21:418 Bocconia arborea 27:163,170 Bocconia cordata 26:488 Bocconiafrutescens L. 27:163 Bocconia genus 27:162 Bocconia integrifolia 27:163 Bocconia pearcei 27:163
120
Bocconia sp. 27:155 Bocconine 26:488 Bocconoline 27:168 (3 R,4R,5S)-N-BOC-dolaisoleucine 12:486 (• oc-L-phenylalanyl 22:280 N-BOC-L-threonine methyl ester 12:430 from methyl trans (4S,5R)-5methyl 3-tert butoxycarbonyl-2oxo-oxazolidine-4-carboxylates 12:430 N-BOC-proline 19:54 N-BOC-tyrosine 16:609 photooxygenation of 16:609 Boekman-Silver synthesis 6:18 of (-)-[5-gorgonene 6:18 Boerhavia diffusa L. 22:514;26:233 as anticonvulsive agent 22:514 liriodendrin from 26:233 Boerhavia repens L. 22:514 Boesenbergia 23:819 Boesenbergia pandurata 23:819;29:775 Boesenbergin A 23:821 Boesenbergin B 23:821 Bohadschia argus 7:270 bivittoside B,C from 7:270 Bohadschia bivittata 28:589 bivittosides A, B, C and D from 15:91 Bohadschia graffei 7:269 holothurins A,B from 7:269 holothurin A2 from 7:269 Bohadschia marmorata 7:270 bivittoside B,C from 7:270 Bohadschia tenuissima 7:270 bivittoside B,C from 7:270 Bohadschia vitensis 7:270 bivittoside B,C from 7:270 Bolabella auricularia 27:804 Bolbostemma paniculatum 7:143,144; 21:639 tubeimoside I from 21:645,665 Boldine 21:52,57,96,97,102,108 Boletinus cavipes 20:26 Boletopsis grisea (Polyporus griseus) 29:277 Boletopsis leucomelaena 29:284 Boletus edulis 5:289
Bolinea lutea 22:249 Bolivianol 30:711 structure of 30:711 Boll weevil pheromone 1:693 Bombax malabaricum DC. 22:514 for epilepsy 22:514 Bombesin analog 27:797 from emphibianskin 27:797 Bombesin receptor antagonists 28:221 from Morus species 28:221 ofkuwanon G 28:221 of kuwanon H 28:221 Bombesin-induced phospholipase C activity 15:447 Bombina variegata 23.341 Bombsin 27:797 biological activity of 27:797 Bombyx mori 5:832;19:647;22:396; 23:661 ;26:991 ;29:6,10,25 Bonafousine 5:128 Bonanzin 7:226 Bone calcium mobilization 9:514; 30:484 role of vitamin D2 in 30:484 Bone marrow hypoplasia 26:688 Bone mobilization 30:497 assay for 30:497 in vivo 30.'497 Bone resorbing " ~tivity 30:495 of la,25tOH)2D2 30:495 of lct,25(OH)2D4 30:495 of la,25(OH)2D3 30:495 Bone resorption 21:702 inhibitory activity on 21:720 inhibitory effect on 21:702 Bonnet de Pretre 23:655 Boophiline 25:706 Boophilus decoloratus 28:396,400 Boophilus microplus 25:706;28:398,402 essential oils from 28:398 Boophilus sp. 28:401,402 9-Borabicyclo [3.3.1 ] nonane (9-BBN) 13:72 Borage oil 13:659 Boraginaceae 21:3,97 Borane-methyl sulfide complex 11:360 Boration 9:366-368 Bordeaux terpentine 29:83
121 Bordetella pertussis 25:521,538 Borealosides A-D 15:71 Boric acid 25:674 Borjatriol 25:249,250;29:102 activity in CTN bioassay system 29:102 Bormination 4:629,633,634,656,657 of camphor 4:629,633,634, 656,657 of camphor derivatives 4:629632,633,634,636,656-658 1-Borneol 10:52 Borneol 9:530;21:598,601;25:128,154 (+)-Borneol 27:376 structure of 27:376 Born-Oppenheimer approximation 2:155 Borntr~iger reaction 26:644 (+)-Bornyl acetate 4:645,46,648 Boromycin 5:377,414,11:207,208 Boron aldolate 30:23 in situ reduction of 30:23 Boron enolate 13:500 of 3 (R)-3-hydroxybutanethioate 13:500 Boronic ester 11:409 Borophycin 21:303,316 Borrecarpin 11:278 from Borreria capitata 11:278 Borrelia burgdorferi 21:646;26:695 Borreria capitata 11:278 borrecarpin from 11:278 Boschnialactone 8:140,155-157; 20:72,74,76;16:701 Bose reaction 4:440,441 by 3-hydroxybutyric acid 4:440,441 by ketene-imine cycloaddition 4:440 in azetidinone formation 4:440, 441 Boswellia serrata 22:126,136;29:585, 586,691 [3-Boswellic acid (triterpene) 29:585 effects on leukocyte ELA 29:585 Boswellic acids 22:110,116,120 Botanical/ecological description 27:661
Botanical juvenile hormones 18:498 Bothriochloa bladhi 11:278 eudesm- 11-en-4-ols from 14:450 (+)-intermedeol from 14:450 neointermedeol from 14:450 Bothriochloa glabra 14:450 eudesm-11-en-4-ols from 14:450 (+)-intermedeol from 14:450 neointermedeol from 14:450 Bothriochloa grasses 14:450,451 intermedeol from 14:450,451 neointermedeol from 14:450,451 Bothriochloa insculpta 14:450,451 eudesm-11-en-4-ols from 14:450 (+)-intermedeol from 14:450 neointermedeol from 14:450 Bothriochloa intermedia 14:449- 451 eudesm- 11-en-4-ols from 14:449-451 intermedeol from 14:450,451 neointermedeol from 14:450,451 Botryllamide A 23:241 Botryllamide B 23:241 Botryllamide C 23:241 Botryllamide D 23:241 Botrylus leactis 25:706 Botrylus schlosseri 25:719 Botryodiplodia malorum 25:143 Botryospheria obtusa 25:318 Botryotinia fuckeliana 12:400 Botrytis 4:246 Botrytis cinerae 5:598;21:196,213,217; 22:459,45 ;25:138,305,313,314,316, 662;26:404,405,508,553,555 ;27:768 Botrytis fabae 2:434 Botulinum 13 21:16 Botzella sp. 25:790 (-)-[3-Bourbonene 10:405,406 Boussingaultia baselloides 21:666 12,20(29)-diene- 30-noro leano lic acid from 21:666 Bouvardia ternifolia 24:306,309,319 bouvardins from 10:640 Bouvardins 10:640 from Bouvardia ternifolia 10:640 Bovine brain FPTase activity 24:446 of cylindrols 24:445-447 Bovine endothelin 25:841
122
Bovine insulin 2:45 molecular ion region 2:45 Bovine papillomavirus type 1 30:406 microbicidal compound against 30:406 Bovine serum albumin (BSA) 7:114, 115;22:374;27:330;30:837,844 F-II hydrolysis of 30:837 phytolysis of 27:330 Bowlesia 27:661 Bowman-Birk protease barley rootlet BBI 29:599 barley seed BBI as 29:599 bsil (fungus-induced) as 29:599 Coix BBI TI-1 as 29:599 dual function a-amylase/trypsin CM (chloroform-methanol soluble proteins) 29:602 OsBBPI as 29:599 RBBI-8 as 29:600 RBTI as 29:599 WIP1 variants (genes) as 29:600 WTI (BBI Type I), as 29:600 Bowman-Birk serine protease inhibitor proteins 29:598 A-I as 29:598 A-II as 29:598 B-I as 29:598 B-II as 29:598 B-III as 29:598 ATI (alfalfa trypsin inhibitor) as 29:598 BBI-1 as 29:598 BBPIP as 29:598 BTCI as 29:599 C-II as 29:598 CLTI-I as 29:598 CLTI-II as 29:598 CPTIs as 29:599 DATI as 29:598 DE-1 as 29:598 DE-2 as 29:598 DE-3 as 29:598 DE-4 as 29:598 DgTI as 29:598 D-II as 29:598 EBI as 29:598 E-I (PI-I) as 29:598 FBI as 29:599
HGI-III as 29:598 I (ABI-I) as 29:598 I-A, I-B, I-A', II, II', I I-A as 29:598 Boy6/Brossi 29:378 allocolchicinoids total synthesis by 29:378 Boyer and Hanna 29:497 carbaoxirose/carbaoxetoses synthesis by 29:497 Boyer and Lallemand 29:499 homochiral (+)-calystegines B2 synthesis by 29:499 homochiral (-)-calystegines B2 synthesis by 29:499 BPV-4 (Bovine papilloma Virus type 4) 26:761 Brabeium 26:1157 Brachyoside A 25:197 Brachyoside B 25:192 Brachyoside C 25:197 Brachyponera sennaarensis 5:224,225, 254 Bracken carcinogens 26:705 Brackenridgea zanguebarica 7:408; 23:342 Bractazonine 6:478,487,270 Bradsher cycloaddition 24:630,631 Bradycardia 30:191,194 as pain mediator 30:192 due to opioids 30:194 Bradykinin 9:296,298 from Rana nirgomaculata 9:296 from Rana temporaria 9:296 Bradykinin B2 receptor 30:203 interaction with ginseng 203 Bradykinin induced edema 25:46 inhibition of 25:46 Bradykinin receptors 21:73 Bradyrhizobium sp. 26:1154,1155 Brafouedine 9:172 Brain 30:192,383 COX 3 enzyme in 30:192 serotonin (5-HT) receptors in 30:383 Brain development 30:375 serotonin (5-HT) 5A receptor in 30:375
123
Brain enzymes 30:816 resistance to 30:816 Brain membrane synaptosomes 30:814 radioligands from 30:814 Brain neurons 30:371 Brain processes 30:367 role ofserotonin 30:367 Brain stem 30:370 tryptophan hydroxylase (TPH) in 30:370 Bramia monnieri L. 22:513 for epilepsy 22:513 8-Bramodesoxypicropodophyllin 18:593,596 Branched amino sugars 10:421 synthesis of 10:421 Branched chain nucleosides 4:254-257 synthesis of 4:254-257 Branched decarbonucleotide 14:299,302 synthesis of 14:299,302 Branched hexaribonucleotide 14:291, 292 synthesis of 14:291,292 C-Branched nucleoside analogues 19:511-547 stereoselective synthesis of 19:511-547 Branched oligoribonucleotides 14:283-303 synthesis of 14:283-303 Branched RNAs 14:293 synthesis of [A(2'-pX)pX] 14:293 synthesis of [A(2'-pY)pX] 14:293 synthesis of [A(2'-pU)pU 14:293,294 synthesis of [CpUpA(2'-pGpU) pUpC] 14:299,301 synthesis of 14:284-303 via 3'-bis(2-cyanoethoxy) phosphoryl group 14:291,292 via 2',3'-bisphosphorylated ribonucleoside unit 14:284-290 via phosphoramidite approach 14:293,294 Branched tetrasaccharide 10:476,477 synthesis of 10:476,477
Branched triribonucleotide 14:294,295 synthesis of [A(2'-pA)pA] 14:294,295 synthesis of [A(2'-pG)pC] 14:289,290,297-299 synthesis of [A(2'-pG)pU] 14:290,298-300 synthesis of [A(pG)pC] 14:289,290 synthesis of [araA(2'-pU)pU] 14:294 synthesis of [GpA(2'-pG)pC] 14:295-297 synthesis of [pA(2'-pA)pA] 14:294,295 synthesis of [pppA(2'-pA)pA] 14:294,295 synthesis of [U(2'-pA)pU] 14:296,297 Branched trisaccharide 10:476,477 synthesis of 10:476,477 Branch-point specificity 7:32,33 of glycohydrolase 7:32,33 Brasilane sesquiterpene 18:633 from Laurencia implicata 18:633 from Laurencia obtusa 18:625 epi-Brasilenol 6:6 from Aplysia brasiliana 6:6 from Laurencia obtusa 6:6 synthesis of 6:6,7 (+)-Brasilenol 6:7,8 stereoselective reduction of 6:7,8 Brasilenol 6:8 by o~-dimethylation 6:8 by Wacker oxidation 6:6 from Aplysia brasiliana 6:6,249 from brasilenone 6:7,8 fromLaurencia obtusa 6:6 synthesis of 6:6,7,625 Brasilenol acetate 6:8 from Aplysia brasiliana 6:6 from Laurencia obtusa 6:6 synthesis of 6:6,7 Brasilenone 6:7,8 Brasiliensoside 15:55 Brassica (SRK) 25:368,386 Brassica BN 29:618
124
Brassica compestris L. 19:246;26:187, 481 Brassicajuncea 24:57,60 Brassica napus L. 18:495,498;19:245; 25:413 ;27:217;29:603,612,618 Brassica nigra L. 22:514;29:618 for epilepsy 22:514 Brassica oleraceae 26:748;29:603,612 Brassica rapa 28:425 Brassica sp. 23:756 Brassica TIBN 29:618 Brassicasterol 16:324 from canola oil 16:324 Brassin 25:413 Brassino steroid precursors 25:415 Brassinolide 16:321 antiecdysteroid activity of 16:321 biological activity of 19:245,281 chemical structure of 19:245 from Brassica napus 18:495 isolation of 19:245 plant growth promoters 16:321; 19:245 structure-activity relationship of 19:281 Brassinolide 25:415-416 Brassinone 18:500 Brassinosteroid 25:316,413,420,425, 367 Brassinosteroid biosynthesis 18:520 Brassinosteroid intermediates 25:414, 417 Brassinosteroid metabolites 18:534-546 Brassinosteroid pathway 25:421 Brassinosteroids 19:245-287,473 antiecdysteroid activity of 16:321 application of 19:242-287 biological activity of 19:473 biosynthesis of 19:283 construction of side chain of 19:245-287 from Brassica napus 19:473 isolation of 19:473 metabolism of 18:520-533 stereoselective synthesis of 16:321-364
structure novelty of 19:473 synthesis of 19:245-287 Brassinosterol pathway 25:426 Braun homogenizer 19:692 Braxins A1 26:704 Braxins A2 26:704 Brazilin 20:777,780 Brchtold et al. 29:200,203 triptolide synthesis by 29:200, 203 Breast cancer 24:933 Bredereck's reagent 8:262,316 Bredius mandebularis 1:684 Bredius spectabilis 1:684 Bredt's rule 12:72 Brefeldin 26:452 Brefeldin A 8:140,149;27:871 Brein 29:586;30:206 effects on CHY 29:586 use in inflammatory skin conditions 30:206 Brein 3-O-myristate (urs- 12-ene3~,16~-diol 3-O-myristate) (triterpene) 29:586 effects on CHY 29:586 Brein 3-O-palmitate (urs- 12-ene3~, 16~-diol 3-O-palmitate) (triterpene) 29:586 effects on CHY 29:586 Brenania sp. 21:125 Brenzcatechin 15:328 Brettanomyces anomalus 5:283 Brettanomyces bruxellensis 5:283 Brettanomyces dublinensis 5:283 Brettanomycesmyces lambicus 5:283 Brevetoxin 25:730,864 Brevetoxin A 10:208 Brevetoxin B 10:201,203-205 Brevetoxin B1 25:864 Brevetoxin B2 25:864 Brevetoxin B4 28:656 as toxin 28:656 from Perna canaliculus 28:656 in shellfish poisoning 28:656 Brevetoxins 21:300,301 (+)-Brevianamides A and B 17:475 Brevibacterium ammoniagenes 20:32 Brevibacterium divaricatum 6:385
125
exo-Brevicomin 1:637,'11:413 enantioselective synthesis of 1:637 from Dendrocotonus brevicomis 11:413 synthesis of 11:413,414 Brevicomins 13:328 Brevicoryne brassicae 23:66 Brevifoliol 20:100 Brevilin A 26:809 Brewer's wort 25:139 Briareum excavatum 25:670 Brickellia lemmonic 25:230 Brickellia veronicaefolia 5:680 Brickellin 5:673-677 2,6-Bridged 3-benzazocines 6:471 in benzomorphans 6:471 Bridged bicyclo [4.2.2] ring system 12:65 Bridged C-disaccharides 10:367 from (x-methylene lactones 10:367 Bridged systems 6:65-87 Brine shrimp 9:385,387-400;24:864,865 bioassay of 24:864,865 lethality bioassay of 9:385, 387-400 Brine shrimp bioassay 30:733 Brine shrimp toxicity 9:395;24:944-950 of endophytic fungi 24:944-950 of Goniothalamus giganteus 9:395 Bripiodionen 28:117,118 as human cytomegalovirus protease inhibitors 28:118 cytotoxicity of 28:118 Broad spectrum activity 28:332 of anthelmintics 28:332 Brochamin 26:745 Bromelain 30:840 Brominated aminoimidazolinylindole 25:763 Brominated compounds 17:9 amides 17:84 diphenylether 17:9 phenols 17:81 phenylether 17:9 Brominated indole alkaloids 25:712 Brominated phenylethylamine 25:765
Brominated terpenoids 6:24,56 Bromination 14:269 3-bromo-levoglucosenone 14:269 chemoselective 19:314 Bromination-dehydrobromination sequence 12:237 Brominative cyclization 6:24 in brominated terpenoids 6:24 in glanduliferol synthesis 6:63,64 of ( 8R/S,9R/S)-8-brome-9hydroxy-(E)-bisabolene 6:62,63 Brominative rearrangement 4:474 4-Bromo-azetidinone 4:474 Bromine addition 16:336 Bromlactonisation 8:301 ofbromolactone 8:301 of (4S)-3-methylmuconolactone 8:300,301 5-Bromo- 1,2-dihydroacronycine 20:789 3-Bromo-2,5-dimethyloxyanitine 21:442 6-Bromo-2-1ithio-6-methyl-2-phenyl heptane 8:6,7 2-Bromo-3,3-diethoxy-l-propene 2:36 1-Bromo-3E, 5E-decadienoyl bromide 23:191 9-Bromo-3-endo-methyl camphor 4:630,631 acid catalysed rearrangement 4:630,631 reactivity towards bromination 4:629 3-endo-Bromo-3-exo-methyl camphor 4:657,658 2-Bromo-3-hydroxybutyric acid 4:473-475 (R)-l-Bromo-3-methylnonanol 26:66 trans-5-Bromo-4-methoxy derivatives 12:419-421 as 2-amino alcohol synthon 12:418-421 diastereselectivity of 12:419-421 from 3-acyl-2-oxazolone 12:418, 419 from 3(1S)-ketopinyl-2oxazolone 12:419-421 4-Bromo-5-ethoxysampangine 23:6
126
6-Bromo-5-hydroxy indole 25:792 6-(p-Hydroxyphenyl)-2H-3,4dihydro- 1,1,-dioxo-l,4-thiazine 25:862 7-B romo-6,8-dihydro xy-3-propyl-3,4dihydro-isocoumarin 15:386 9-Bromo-6-endo-methylisofenchone 4:630,631,635 synthesis of 4:630,631
(8R/S,9R/S-8-Bromo-9-hydroxy-(E)- T-
bisa bolene 6:62,63 3'-Bromo-ABA 27:353 (E)-[3-Bromoacrylamides 21:382 [3-Bromoacrylates 8:141 (E)-3-Bromoacrylates 8:150,151 synthesis of 8:150,151 Bromoagelifterin 25:779,780 7-p-Bromoanilino-7-demethoxy mitomycin 13:434 X-ray crystal structure of 13:434 Bromoapotrichothecene 6:2342Bromobenzene 25:460 11-Bromobenzoate 7:389 of 11-hydroxycanthin-6-one 7:389 X-ray analysis of 7:389 p-Bromobenzoyl derivative 25:816 N-(p-Bromobenzoyl) palytoxin 5:391,393 4-Bromobenzyltryptamine 26:125 Bromoboronylether 30:214,215 boron tribromide from 30:214 conversion of 30:215 (+)-9-Bromocamphor 16:128 9-Bromocamphor 16:133 (+)-5-Bromocamphor 16:144 (-)-6-Bromocamphor 16:148 (+)- 10-Bromocamphor 4:628,629 from (+)-3,3-dibromocamphor 4:628,629 (+)-endo-3-Bromocamphor 4:628,633, 634 acid catalyzed rearrangement of 4:635,643 bromination of 4:656,657 sulphonation of 4:628,633,634 (+)-9-Bromocamphor 4:633-635,657, 658
8-Bromocamphor 4:640,641;16:135 synthesis of 4:640,641;16:135 (+)-endo-6-Bromocamphor 4:644 from (+)-cx-pinene 4:644 (+)-exo-5-Bromocamphor 4:646 synthesis of 4:646 (+)-3-Bromocamphor- 8-sulfonic acid salt 12:279 Bromocarbenoid procedure 1:263 Bromocarbenoid ring expansion 1:263 Bromochamigrene 6:60,61 by spiroannulation 6:60,61 by Wittig reaction 6:61 from cyclohexanone aldehyde 6:61 from Laurencia majuscula 6:60 from phenolic c~-diazoketone 6:60,61 synthesis of 6:60-62 (Z)-3-Bromo-cinnamate 20:789 Bromoconduritol B epoxide 7:38,39 with [~-glucosidase 7:38,39 Bromoconduritol F 7:38,39 with [3-glucosidase 7:38,39 Bromocontryphan 21:320,321 T-Bromocrotonate 21:383 Bromocryptine 13:658 2-Bromocyclohexanone 12:247 cx-Bromocyclohexenones 4:18,19 hydroindolenones from 4:18,19 2-Bromocyclopentenone 10:48 Bromodecanal 26:83 wittig reaction of 26:83-91 8-Bromodesoxypodophyllotoxin 18:593,595 1-cx-Bromo-desoxypodophyllotoxin 18:598 1-[3-Bromo-desoxypodophyllotoxin 18:598 T-Bromodienamide 21:400 Bromodilactone 8:301 absolute configuration 8:301 X-ray analysis of 8:301 relative configuration of 8:301 2-(2-Bromoethyl)- 1,3-dioxolane 26:80 7-Bromo-eudistomidin D 23:266 Bromohydrin formation 1:523 3-Bromohymenialdisine 21:270
127 6-Bromoindole-3-aldelyde 23:257 Bromolactonization 3:265,336-339,177 3-Bromo-levoglucosenone 14:269 from levoglucosenone 14:269 Bromomesylate 19:229 c~-(Bromomethyl)acrylate 30:470 condensation with 30:470 Bromomethylethoxylate 30:443 4-Bromomethylphenyl 2,3,4,6-tetra-Oacetyl-ot-D-galacto-pyranoside 21:165 4-Bromomethylsampangine 23:6 6-Bromo-Nb-methyl-Nbformyltryptamine 18:691,726 18-Bromo-octadeca- 15,17-diene- 15ynoicacid 25:802 Bromoperoxidase 19:454 Bromophakellin 21:270 o-Bromophenacyl okadaate 5:389 2'-Bromophenoxy ether 21:284 p-Bromophenylboronate derivative 8:19 2'-Bromopodophyllotoxin 18:576 Bromopuupehenone 15:299 2-Bromopyridine 6:312 2-pyridine carboxaldehyde from 6:312 Bromopyrrole alkaloids 25:762 5-Bromopyrrole-2-carbamide 25:780 Bromopyrroles 25:711,712,779,784 Bromorebeccamycin 12:366,368 from Saccharothrix aerocolonigenes 12:366,368 3-Bromosampangine 23:6 4-Bromosampangine 23:6 N-Bromosuccinimide 21:162 (-)-Bromothebaine 18:87 2-Bromothiazole 30:443 Bromotyrosin derivative 25:766 3-Bromotyrosine 21:307 Bromotyrosine 23:241;25:642 derivatives 25:766 Bromotyrosine alkaloids 25:712 Bromoxynil 26:374 o~-Bromo-o~-arylacetic acid 6:321 synthesis of 6:321 10-Bromo-ot-chamigrene 6:60 from geranyl acetone 6:60
from Laurencia species 6:60 synthesis of 6:60 (+)-2-Bromo- [3-chamigrene 6:63 from Laurencia pacifica 6:63 Bronchitis 30:58,88 Ganoderman lucidum in treatment of 30:58 Platycodon grandiflorum in treatment of 30:88 Bronchodilators 5:759 in treatment of asthma 5:759 Broncholytic activities 21:633 Brook-Rubottom-Hassner oxidation 12:25,26 ofenol silane 12:25,26 Brosimone A 28:201 from moraceous plants 28:201 Brosimone D 28:201 from moraceous plants 28:201 Brosimones 17:456 Brosimopsis oblongifolia 28:203 Broussoaurone A 28:16,17 antioxidant activity of 28:16,17 as cyclooxygenase inhibitor 28:16,17 as neutrophils respiratory burst inhibitor 28:16 as nitric oxide production inhibitor 28:16 as platelet aggregation inhibitor 28:16,17 Broussochalcone B 28:228 biological activity of 28:228 Broussoflavan A 28:16 antioxidant activity of 28:16 as platelet aggregation inhibitor 28:16 Broussoflavonol B 28:226,229 anti-human immunodeficiency virus (HIV) activity of 28:226 biological activity of 28:229 Broussoflavonol C 28:226,229 anti-human immunodeficiency virus (HIV) activity of 28:226 biological activity of 28:229 Broussoflavonol E 28:17,230 as platelet aggregation inhibitor 28:17 biological activity of 28:229
128
Broussoflavonol F 28:17 antioxidant activity of 28:17 antiproliferative activity of 28:17 as aromatase inhibitor 28:17 as cyclooxygenase inhibitor 28:17 as platelet aggregation inhibitor 28:17 Broussoflavonol G 28:17 antifungal activity of 28:4 antiinflammatory activity of 28:4 antioxidant activity of 28:4,17 antiproliferative activity of 28:17 antispasmodic activity of 28:4 sexual potency of 28:4 Broussonetia genus 28:3 Broussonetia kazinoki 28:3-5 antifungal activity of 28:4 antiinflammatory activity of 28:4 antioxidant activity of 28:4 antispasmodic activity of 28:4 broussonetine C from 28:5 broussonetine D from 28:5 broussonetine E from 28:5 broussonetine F from 28:5 broussonetine G from 28:5 broussonetine H from 28:5 broussonetine K from 28:5 broussonetine L from 28:5 broussonetine M from 28:5 broussonetine N from 28:5 broussonetine O from 28:5 broussonetine P from 28:5 broussonetine Q from 28:5 broussonetinine A from 28:5 broussonetinine B from 28:5 broussonol A from 28:6 broussonol B from 28:6 broussonol C from 28:6 broussonol D from 28:6 7,4'-dihydroxyflavan from 28:6 for increased vision 28:4 kazinol A from 28:6 kazinol D from 28:5 kazinol E from 28:6 kazinol K from 28:5 kazinol Q from 28:6 kazinol R from 28:6 sexual potency of 28:4
Broussonetia papyrifera 27:834;28:3,4, 16,22;29:793 anti-cancer activity of 28:4 antifungal activity of 28:4 antioxidant activity of 28:4 diaphoretic activity of 28:4 in dyspepsia 28:4 in pregnancy 28:4 laxative activity of 28:4 Broussonetia zeylanica 28:3,4,28 aromatase inhibitory substance from 28:4 broussonetine from 28:28 cytotoxic flavonoids from 28:4 3,4 '- dihydroxy-2,3 '-b ip yridine from 28:28 8-hydroxyquinoline-4carbaldehyde from 28:28 8-hydroxyquino line-4carbaldehyde oxime from 28:28 glycosidase inhibitory alkaloids from 28:4 Broussonetine 2:242,244-246;5:752 Broussonin A 28:16 antifungal activity of 28:16 as aromatase inhibitor 28:16 Broussonin B 28:16 antifungal activity of 28:16 Brown and Robin 29:392 steganes synthesis by 29:392 Brown's crotylboration 18:280 Brownioside 15:191 Broxil 17:616 Bruccantin 5:39-41 Brucea antidysenterica 23:285 quassinoids from 7:374-376 Bruceajavanica 23:292;26:211 bruceoside-A from 7:371 bruceoside-B from 7:377 guaiacylglycerol-~-O-6'-(2methoxy) cinnamyl alcohol from 26:211 quassinoids from 7:377-379 Brucea sumatorana 7:391 Bruceanol-C 23:313 Bruceanol-G 23:289,313 Bruceanol-H 23:313 Bruceantarin 7:374;23:285
129 Bruceantin 7:369-374,383,386-388, 391,392,396,398,71-73,79-95,654, 657;23:285,313 Bruceantin-4,5-epoxide 7:388 Bruceantin-5'-ol 7:388 Bruceantinol 7:374,375,392 4,5-Bruceantinolefin 7:388 Bruceantinoside A-C 7:375-377 Bruceantinoside-A 23:313 Bruceantinoside-B 23:313 Bruceantinoside-C 23:288,313 Brucein A 7:378,392,394-396 Brucein B 7:392,395,396;23:304 Brucein C 7:375,388,394,396;23:304 Brucein D 7:377,391,392,397;23:312 Brucein E 23:312 Bruceolide 7:371,391,392,392 15-[(E)-non-Z-enoyl]-Bruceolide 7:395 Bruceoside-A 7:371 from Bruceajavanica 7:371 Bruceoside-B 7:377;23:312 from Bruceajavanica 7:377 Bruceoside-C 23:312 Brucine 9:189;26:1030,1049 Brucine N-oxide 26:1049 Brugierol 7:193,194 Brugine 7:191,192 Bruguiera conjugata 7:193,194 Bruguiera cylindrica 7:176,193,194 Bruguiera exaristata 7:191 Bruguiera gymorhiza 7:176,180-182, 188,195 Bruguiera parviflora 7:180,195 Bruguiera sexangula 7:176,191 Bruguiera sp. 7:176 Brusatol 7:79,377,383,387,392,394,397, 11:80;26:815,816 Brusatolyl ester 7:377,383 Bryonia alba 20:13 Bryonia dioica 15:24;20:13;22:121; 27:14,25;29:614 bryoclulcoside from 27:14 bryonoside from 27:14 bryoside from 27:14 Bryonolic acid-3-succinatel 22:121 Bryonoside 15:24;27:14,25,26 from Bryonia dioica 15:24 structure of 27:26 Bryophyta 27:735
Bryophytes 2:277;20:468;26:185 sesquiterpenes of 20:468 Bryoside 15:24;27:14,25,26 from Bryonia dioica 15:24 structure of 27:26 Bryostatin 19:572;25:684,726,726; 27:832 as anticancer drugs 19:550,572 derivatives 25:727 pharmacological aspects of 19:572 Bryostatin A and B 18:716 Bryozoa 21:3,316 Bryozoan 17:74;21:360;25:825 ;28:618 as moss animal 28:618 lophophore of 28:619 sulfur-containing 28:618 taxonomy of 17:74 U-shaped gut of 28:619 zooids of 28:619 Bryum argenteum 2:277 BSA (Bovine serum albumin) 7:114, 115 Bt2 cAMP 25:489,496 Bt2 cAMP-treated carrot cells 25:490 Btg C 21:751
Buchenavia capitata 21:132 Buchenavianines 21:132 Biichi and Powell 29:472 carbaaldopyranoses synthesis by 29:472 Buchnera cruciata 22:514 Buddleja davaidii 20:644 buddlenol A from 20:644 Buddleja globosa 29:686 Buddleja madagascariensis 21:660 Buddlejasaponin 27:672,677,688 Buddlenol A 20:644 from Buddleja davidii 20:644 Buddleyasaponin IV 21:656 Budleyasaponin 21:674 Budmunchiamines 22:28 Bufadienolide 25:535 Bufadienolide Scillaren A 25:535 Bufo regularis 2:310,804;26:689 Bufobufo gargarizans 24:904-905 sterols from 24:904-905 Bufogenins 15:328 Bufonidae 21:89
130 Bufonis 24:904 inhibition of capillary permeability by 24:905 Bufotenidin 15:328 Bufotenine 15:328;21:68;25:531 Bugula dentata 17:88 Bugula neritina 5:394,395,153,75,77, 89,92,18:573-574,576,715,716; 21:252,316,317;25:726 bryostatin from 21:252 Bugula trubinata 17:102 Bugula turrita 17:80 Bugularia dissimilis 17:95,101 "Built-in auxiliary" 14:552 (+)-Bulbocapine 16:509 Bulbocapnine 21:733 Bulgarane 15:247 Bulgaria inquinans 26:450 Bulgarian rose oil 25:132 Bulgecinine 14:193 (-)-Bulgecinine 16:706-707 Bulimia 30:369 effect of circadian activity on 369 Bulinus 7:426,432 Bulinus globosus 7:432,434 Bullatacin 9:396-398,252,266,271-272 Bullatacinone 9:396-398,266,278 Bullatalicin 9:397,398 Bullera sp. 5:291 Bulleyanin 15:119,126,133,171 Bulnesol 1:545 (d/)-Bulnesol 10:310,311 (+)-Bulnesol 14:364,365 Bungarotoxins 18:698 c~-Bungrarotoxin 21:52 Buntanin 13:350 from Citrus grandis 13:350 Buntenolides 24:521,522 as antiviral compound 24:521, 522 Bunya virus infection 30:410,411 mouse model for 30:411 treatment of 30:411 Bupalus piniarius 4:566 Buparvaquone 26:804 Buphanisine 4:14-17 asymmetric synthesis of 4:14,15 from Amaryllidaceae 4:3,4 synthesis of 4:13-17
Buplerom falcium 24:146,148
Bupleuroside III,IV,XIII 25:474 hepatoprotective activity of 25:474 Bupleurum bourgeaei spp. 27:662 Bupleurum chinense 27:660 Bupleurum falcatum 21:665,688; 25:474;27:660 saikosaponin from 21:665 Bupleurum fruticosum 17:117,127; 21:656; 27:693 Bupleurum genus 27:687 Bupleurum gibraltaricum 27:660,661 Bupleurum kaoi 27:660,693 Bupleurum marginatum 27:660 Bupleurum radix 21:651 ;25:474 saikosponins from 21:651 Bupleurum rigidum 27:659,662,663665,669,675,678,693 bioactive components of 27:659 biological activity of 27:688,693 roots of 27:665 Bupleurum rotundifolium 27:672 Bupleurum salicifolium 26:229 Bupleurum scorzonerifolium 25:474, 476;27:660,675 triterpene glycosides of 25:474 Bupleurum sp. 21:671,686 from roots 27:686 saikosaponins from 21:671 Bupremorphine (18,19-dehydrobupremorphine) 30:198 dehydroderivative of 30:198 derivative of 30:198 structure of 30:198 Burasaia madagascariensis 26:1038 Burchellin 8:160 synthesis of 8:160 Burgess reagent 1:16,50,53,232,257, 296,601 ;24:178,179 Burkholderia 26:582,605 Burkholderia caryophylli 26:594,599, 601,602,605 Burkholderia cepacia 26:605 Burkitt's lymphoma 26:926 Burning bush 23:655 Bursaphelenchus lignicolus 12:398; 26:429,435,493 Bursaphelenchus xylophylus 26:436,
131 442,466,470,471,474,485,487 Bursaphelocide A&B 26:485 Bursehernin 18:554,556;26:192,229; 30:568,592 as EBV inhibitor 30:592 Bursen 26:191 Bursera ariensis 17:317 Bursera microphylla 17:330 Bursera permollis 26:216-219 cholchicine from 26:216 4 '- de metho xy- 3 ',4 '-methylenedioxy-methyl rocaglate from 26:218 deoxypodophyllotoxin from 26:216 1-oxo-4 '-demethoxy- 3 ',4 'methyl-enedioxyrocaglaol from 26:218 4'-episteganangin from 26:216 (-)-deoxypodophyllotoxin from 26:218 1-O-formyl-4'-methylenedioxymethyl-rocaglaol from 26:218 methyl rocagalate from 26:218 obavatifol from 26:219 obovaten from 26:219 obovatinal from 26:219 [3-peltatin methyl ether from 26:216 perseal A from 26:219 perseal B from 26:219 perseal C from 26:219 perseal D from 26:219 steganangin from 26:216 stegancin from 26:216 steganoate B from 26:216 steganolide A from 26:216 (-)-yatein from 26:218 Bursera schlechtendalii 18:556 Burseraceae 18:558;17:370 Burseran 17:330 trans-Burseran 24:747,748 Bush beans 9:393 (Z)-But-2-ene- 1,4 diol 6:116 1-But-3-enyl-5-hydroxy-5-methylpyrroldin-2-one 12:289 with trans-7-fromyloxy-8amethylindolizidine 12:289
Butadiene 11:341 trans- cyclohexenecarboxylic acid from 11:340,341 (S)-Butan-l,2,4-triol 6:287,289 from (S)-malic acid ester 6:287, 289 Butanal 9:338,339 Butane-l,2,4-triol-l,2-acetonide 21:739 (2R,3R)-2,3-Butanediol 1:639 (2R,3 R)-2,3-Butanediol 14:471 benzaldehyde acetal from 14:477 olefinic dioxolane acetal from 14:471 (R, R)-2,3-Butanediol [(IS)- 1-chloroalkyl] boronates 11:412 (2R,3R)-2,3-Butanediol acetals/ketals 1:591,593 (R,R)-2,3-Butanediol esters 11:412 Butanolides 6:295-297 4- 0-Butanoyl-4'-demethyl podophyllotoxin 24:740,741 4- 0-Butanoyl-4'-demethyl podophyllotoxin 24:740,741 cytotoxicity of 24:740 19'-Butanoylfucoxanthine 6:134,135, 138-141 Butea frondosa 26:457 Butea monosperma (Lam.) 22:514 for epilepsy 22:514 Butein 25:546;29:572 effects on HIV- 1 protease 29:572 Butenolide 23:685 Butenylation 12:458 (E)-2-Butenyldiisopinocampheylborane 13:135 3-Butenylmagnesium bromide 12:29,30 (S)-trans-T-Butenynyl (GABA) 14:473 synthesis of 14:473 N-tert-Butoxycarbonylation 12:478,479 N-tert-Butoxycarbonyl-L-alanyl-Disoglutamine benzyl ester 6:409,410 N- tert-Buto xyc arb onyl-L- alanyl- Disoglutamine methyl ester 6:410 t-Butyl acetate 11:127,129 Claisen condensation of 11:127,129 with naphthalene glutarate 11:127,129
132
t-Butyl anthraqumone 17:561 170-NMR spectrum of 17:561 t-Butyl carbamate 23:190 tert-Butyl ester 6:413-415 of disaccharide dipeptides 6:413-415 t-Butyl hydroperoxide 12:323 tert-Butyl hypochlorite 1:451 addition to olefins 1:451 cyclization with 1:11,12 tert-Butyl tin hydride 1:443,444,451 reduction of chlorides 1:443,444, 451 reduction of dithiocarbonate 1:452,453 cis-5-Butyl-2-heptylpyrrolidine 6:438, 439 from glutamic acid 6:438 synthesis of 6:438,439
trans-5-Butyl-2-heptylp yrrolidine
6:438,439 from glutamic acid 6:438,439 synthesis of 6:438,439 (2S,5 R)-cis-5 -Butyl-2-heptylpyrro lidine 6:438-349 from pyroglutamic acid 6:438-349 synthesis of 6:438-440 3-n-Butyl-4,5-dihydrophthalide 22:537, 512 t-Butyl-5-chloro-3-oxopentanoate 8:268 3-Butyl-5-methyloctahydroindolizidine 6:445,447 as (monomorine I) 6:445,447 from 2,6-1utidine 6:445,447 synthesis of 6:445 2-Butylamino-tetrahydro [3-carboline 14:759 N-t-Butylamodiaquine 25:344 4-tert-Butylcatechol 14:617 Butylcholinesterase 21:748 N-Butyldeox-noj irimycin 10:528 2-tert-Butyldihydroxyoxazole 12:411, 413 2-amino alcohol by 12:411,413 electrophilic addition to 12:411, 413 tert-Butyldimethyl silyl ether 6:264, 268;11:339;12:282
tert-Butyldimethylsilyl (TBDMS) group 4:299,304
tert-Butyldimethylsilyl ketene acetal 1:465
tert-Butyldimethylsilylation 6:119,120 8-O-t-Butyldimethylsilyldehydrononactate 18:242
tert-Butyldimethylsilyldehydropodophyllotoxin 18:565 (+)-8-O-tert-Butyldimethylsilylnonactate 18:242
tert-B utyl dime thyls ilylp icropodop h yl lin 18:564
tert-Butyldimethylsilylpodophyllotoxin 18:563 t-Butyldiphenylsilyl ethers (TBDPS) 24:9-11 tert-Butyldiphenylsilyl trifluoromethanesulfonate 1:707,708 N-I-Butyl diphenylsilyl-S-benzyl-Smethyl sulfoximine 10:686-688 t-Butylformamidines 6:430,431 tert-Butylformamidines 6:430,431 Butylidenephthalide 24:890-892 alleviation of cardiovascularinflammation 24:890-892 inhibitory effect on SMCs 24:890-892 (t-Butylimino)-2- [(diethylamino) ]- 1,3dimethylperhydro- 1,3,2-diazaphosphorine 12:3422 2-(t-Butylimino)-2-[(diethylamino)]-l,3dimethylperhydro- 1,3,2-diazaphosphorine 12:342
t-Butyl-N-chloro-N-argentocarbamate
12:219 3-n-Butylphthalide 22:537,512 N-Butylscopolamine 22:728,735 Butyrine 21:297 Butyrolactone II 30:220 structure of 30:220 Butyrolactones 3:252-225 y-Butyrolactone 16:687-726 Butyrospermol 9:288,289,301 n-Butyryl CoA 11:197 in Streptomyces cinnamonensis 11:197 interconversion of 11:197 stereochemical 11:197
133 6-O-Butyrylcastanospermine 12:332 Butyryl-CoA dehydrogenase 20:835 (+)-Buxabenzamidienine 2:185,186, 204,205 (+)-Buxabenzamidine 2:192 structure of 2:192 Buxaceae 21:3 Buxamine- A 2:205 Buxamine - C 2:205 Buxaminol- B 2:205 Buxaminol- E 2:205 (+)-Buxaminol- G 2:183,184 (+)-Buxaminone 2:201,202,204 (+)-Buxanaldinine 2:188,2:189 (-)-Buxanoldine 2:187,204 (-)-Buxapapinolamine 2:190191 (+)-Buxaprogestine 2:199 (+)-Buxaquamarine 2:178,2:179,205 Buxatine 2:205 Buxenine - G 2:205 Buxenone 2:207 Buxocyclamine - A 2:207 (+)-Buxupapine 2:189,205 Buxus alkaloids 2:175,205 Buxus papilosa 2:175 Byakangelicin 23:351,357 Byrsocarpus coccineus 26:69 Byrsonima crassifolia 24:779,826-835 pharmacological activity of 24:828 phytochemicals of 24:828-830 uses of 24:827,828 BZSAM 23:21,44 ~H-NMR assignments of 23:44 BZSAMM 1 23:43 ~H-NMR assignments of 23:44 structure elucidation of 23:43 ~H and ~3C spectra 26:8,9,22,30,33 of aglycone of dianchinenoside G & H 26:36 ofbisdesmoside 26:41 ofdianchinenoside E 26:33,34 ofdianchinenoside F 26:37 of dianchinenoside G and H 26:35 of SAPO 30 26:41 of SAPO 50 26:41
ofsaponarioside A 26:22 ofvaccaroside F 26:30 13C NMR 30:584,586 of (7R,8S,7'R,8'R)-(+)-7'-acetyl5 '-methoxypicropodophyllin 30:586 ofherveline A 30:583 13C NMR data 23:31,195,509,599; 26:321,324,326,329;1052 13C-NMR assignments of 23:31 ~H-NMR assignments of 23:29 for monoindoles 26:1052 of hydroxyframoside A&B 26:326 ofhydroxyomoside 26:321 ofinsularoside 26:321 of isolugrandoside 26:329 of isolugrandoside acetate 26:329 13C-NMR spectra 23:111 of [3-glucans 23:111 of glucan 23:123 of lentinan 23:122 13C-NMR spectral studies 23:55 of rifamycins 23:55 13C-NMR spectrum 21:731,732,733 ~3C-NMR-spectroscopy 23:64 of streptovaricin D 23:64 13-demethyldysidenin from 28:666 13-demethyldysidenin from 28:666 13-demethylisodysidenin from 28:666 C-14 reductase 25:304 C2-P bond analogs 6:357,358 of D-erythritol 6:357,358 of D-fructofuranose 6:357,358 of D-glucopyranoside 6:357,358 of D-ribohexitol 6:357,358 C3-P bond analogs 6:359,360 of D-allofuranose 6:359 of D-altropyranoside 6:359,360 of D-glucofuranose 6:359,360 of D,L-glyceraldehyde 6:359 of D-xylofuranose 6:359 C4-Oxo group 27:924 of catechins 27:924 C40-Carotenoids 6:110,135,136,143,144
134
C4-alkylations 12:159-172 of D-lactams 12:159-172 with ester enolates 12:163,164 with imide enolates 12:164-168 with other nucleophiles 12:170-172 with thiolester enolates 12:168-170 C-4-O-acetyl derivative 28:117 C4-P bond analogs 6:360,363,364 of D-erythropentose 6:360,363, 364 of D, L-glycero-pentopyranose 6:360,361 of D-talopyranose 6:360 of L-talopranoside 6:360 Cs-P bond analogs 6:365,366 of D-erythropentofuranose 6:365,366 of D-ribofurnose 6:365,366,368 of D-xylofuranose 6:365-367, 375 of D-xylo-hexofuranose 6:365, 366,372 C6 oxidation 25:415,424 of 6-deoxocastasterone 25:415, 424 C6-P bond analogs 6:376 of D-arabino-hexo furanose 6:376 of D-erythro-hexofuranose 6:376 of D-galactopyranose 6:376 of D-glucofuranose 6:376 of D-glucopyranose 6:376 of D-ribo-hexofuranoside 6:376 of D-ribo-hexofuranose 6:376 m-CvN unit 23.79,89 C8-Hexanoate 30:27 C8-hexanoate pironetin 30:27 mitogen responses to 30:27 structure of 30:27 suppressive effects of 30:27 Cs-polyketide 12:290 Ca+* Current 22:508 Ca 2§ channels 25:531;30:194 blockade of 30:194 Ca2*/Calmodulin 25:261 Ca2+/CAM-dependent protein kinases 25:489
Ca2+-ATPase 25:492,493,524,536 Ca2+-ATPase inhibitor 25:536 xanthone a-mangostin as 25:531,536 Ca2+-calmodulin (CAM-dependent protein kinase) 25:261,524 CaZ+-Calmodulin complex 26:920 Ca2+-Cam-activated adenylyl cyclase 25:538 Ca-2+CaM-dependent protein kinase 25:522,544,546,547 CaZ+-channel agonists 28:695 Ianthella basta as 28:695 CaZ+-channel blockers 25:489 CaZ+-channels 25:521 CaZ+-dependent CAM 25:491,540 CaZ+-dependent enzymes 25:517 CaZ+-dependent K + channel 25:534 Ca2+-dependent process 25:487 CaZ+-induced LDL oxidation 25:946 CaZ+-inhibitors 25:487 CaZ+-ionophore A23189 25:487,490, 509 Ca2+-mediated signalling 25:526 CaZ+-mediated signalling targets 25:542 Ca2+-permeable ion channel 25:397 CaZ+-pumping ATPase 25:492 Ca2+-translocating ATPase 25:492 activity of 25:492,496 CaZ+-transporting systems 25:492 Caax peptidomimetics 24:413,414 structure of 24:413 Cabreuva oil 17:609;25:162 Cacachila 22:559 Cacaliahastata 19:149 Cacospongia 6:11 Cacospongia linteiformis 25:698 Cacospongiolide B 25:697 Cactaceae 21:3 5'-d(CACTAG (8-Oxo) TCAC) 8:390, 391 Cacticin 7:226 CAD 25:666 Cadabafarinosa 9:64,65 sesquiterpenes from 9:64,65 Cadabicilone 9:64,65 Cadabicine 9:73 Cadabicine methyl ether 5:209,210 cis-Cadalane 6:548,459
135 Cadalene 14:319 Cadambine tetraacetate 9:171-173 Cadaverine 14:739;26:1259,1260 Cadinane 4:584,585 synthesis of 4:584,585 by [2+2] cycloadditions 6:15 from Artemisia annua 7:217 Cadinane sesquiterpenes 15:278 Cadinene 21:282 10-Cadinol 21:584 Cadinol 30:722 structure of 30:722 Cadinolide A 9:9 biogenesis of 9:9 from Cadlina luteomarginata 9:6 X-ray crystal structure of 9:7-9 Cadlina luteomarginata 9:6;21:318, 334,364 ;24:183,184 ;28:659 sesquiterpene isothiocyanate from 28:659 Cadlinaldehyde 21:318 Cadlinolide A 17:15 cADPR 25:527,535 Caenorhabditis elegans 25:785;26:427, 429,432-434,437,439,441,447-449, 451,453,455,457,460-462,466, 468-471,473,474,481,487,488,490, 494,495,884 ;29:321 Caesalpin J 5:17 Caesalpina braziliensis 19:776 Caesalpinia bonduc L. 22:514 for convulsions 22:514 Caesalpinia echinata Lam. 27:37 Caesalpiniapulcherrima L. 20:475; 22:471,514;26:1142 for convulsions in children 22:514 Caesalpinia sappan 5:17 Caesalpinia vesicaria 26:1142 Caesalpiniaceae 25:92 Caesalpinina digyna 23:520 Cafestol 29:101 activity in CYP bioassay system 29:101 activity in GSH bioassay system 29:101 activity in GST bioassay system 29:101
activity in skin-6 bioassay system 29:101 from green coffee beans 29:101 Caffeate esters 30:651 Caffeic acid 5:467,469,474,479,111, 119,579,36;22:126,346,645,663; 23:537,551,740,744 ;25:655,657,663, 671,919,920,922-927,932-934, 936-938;28:262;29:578 effects on ACE 29:578 in apples 28:262 in blueberries 28:262 in cider 28:262 in coffee beverages 28:262 (+)-Caffeic acid 27:421 biological activity of 27:421 Caffeic acid derivatives 23:753 in artichoke 23:753 Caffeic acid tetramer 24:742,743 anti-HIV activity of 24:742 potassium salt of 24:742 Caffeine 21:72,98,109;22:5,7;25:532, 539;28:422 acaricidal activity of 28:422 3-O-3-Caffeoyl-4-O-feruloylquinic acid 25:920 Caffeoylquinic acid 22:353 3,5-Di-O-Caffeoylquinic acid 22:353 4,5-Di-O-Caffeoylquinic acid 22:353 Caffeoylquinic acid 23:740 3'-Caffeoylquinic acid 23:749,750 4'-Caffeoylquinic acid 23:749 1-Caffeoylquinic acid 23:753 3-Caffeoylquinic acid 23:753 4-Caffeoylquinic acid 23:753 4,5-di-Caffeoylquinic acid 23:753 5-Caffeoylquinic acid 23:753 5-O-Caffeoylquinic acid 25:919,920 3-O-Caffeoylquinic acid 25:920,921 4-O-Caffeoylquinic acid 25:920 Caffeoylquinic acids 25:943,944; 27:419;28:262 derivatives 25:465,662 in apples 28:262 in blueberries 28:262 in body tissues 25:924 in cider 28:262 in coffee beverages 28:262
136 Cage-culture turbidostats (CCT) 26:378,382 Caged ABA 27:331,332 Cailicogorgia granulosa 25:670 Caissarone 25:713 Caj anin 27:498 Calabar bean alkaloids 14:636-638 synthesis of 14:636-638 . Calamanenenes 15:251 biosynthesis of 15:251 1R,4S-Calamanenes 15:260 Calamanin B 23:405 Calamanin C 23:405 (+)-Calamenene 15:244,247 from Eremophila drummondii 15:244 Calamenenes (1R,4R) 15:259 Calamus 21:595 Calarene 25:170 Calathrix WA 26:366 Calcemic effects 30:484,495 of lc~,25(OH)zD2 30:495 of lot,25(OH)2D3 30:484,495 of l~,25(OH)2D4 30:495 Calceolaria andina 28:408 Calceolariode A&B 26:327,328 Calceolsareoside A 25:543 Calceolsareoside B 25:543 Calcicolin A i5"119,126,133,171 Calcidiol (25-hydroxyvitamin D3) 11:380 (-)-Calcimycin 16i712-713 synthesis of 16:712-713 Calcinosis cutis 26:675 Calciol (vitamin D3) 11:380 Calcitonin 27:800 Calcitriol 9:520,521,43 Calcitriol lactone 1:604,607 synthesis of 1:604,607 Calcitroic acid 30:502 Calcium alginate 7:92 Calcium antagonistic activity 23:804 of nootkatol 23:804 Calcium chloride 2:414 Calcium effects 12:397 of staurosporine 12:397 Calcium spirulan 30:400,403 chemical analyses of 30:400
structure-activity relationships of 30:403 Calcium uptake inhibitor 28:119 cyclopiazonic acid as 28:119 Calcium/calmodulin-dependent protein kinase 12:389 Calcium-induced contractions 30:748 Calderiella sp. 11:464 macrocyclic lipids from 11:464 Calderol 9:513 Calditol 11:430,464 Calea prunifolia 5:728 Calebassine 25:528 as immunosuppressive drug 25:528 Caledonin 25:813,814 Calendonian 25:697 Calendula arvensis 17:126;21:665 oleanolic acid glycosides from 21:665 Calendula officinalis 22:109,679;25:58 lutein from 7:361 Calenduladiol (lup-20(29)-ene-3 [3, 1613-diol) 29:586 effects on CHY 29:586 Calf intestinal alkaline phosphatase 14:308,309 Calf-thymus vitamin D receptor 30:494 binding assay for 30:494 Calicheamicin Q 25:796 Calicheamicin 7' 25:796 Calicheamicin yl 25:838 Calicheamicinone 10:150 Calicheamycins 10:153;12:489;24:934; 25:796,838 as anti-cancer agent 24:934 Calicoferols 25:705 California red scale pheromone 4:675, 479 Californian sponge 28:671 antiinflammatory activity of 28:671 antimicrobial activity of 28:671 Californium Delasma Desorption (CDD) 24:138 Calli 30:609 Calliandra portoricensis 22:515 as anticonvulsant agent 22:515
137 Callinectes sapidus 19:647,672 Callipelta sp. 25:775;26:1175,1210, 1211,1213 Callipeltins A-C 26:1211,1212,1213 Callipeltoside A 25:775 Callipeltosides 25:757,775 Callipeltosides A-C 26:1210,1211,1213 Calliphora 27:384 Calliphora bioassay 29:25 [3-acetoxy- 14ct-hydroxy-5 [3cholest-7-en-6-one activity in 29:263 as ecdysteroid activity assay 29:25 22-dehydro-25-deoxy-ecdysone activity in 29:26 3-dehydroecdysone activity in 29:26 2-deoxy-20-hydroxy-ecdysone activity in 29:26 22- de oxy-20-hydro xy-ecdysone [taxisterone] activity in 29:26 3-epi-2-deoxy-20-hydroxyecdysone activity in 29:26 25-deoxy-7,8-dihydro-ecdysone activity in 29:26 2f3,14c~,-dihydroxy-5 a-cholest-7en-6-one activity in 29:27 6-oxo-3 c~,14ot-dihydroxy-5 [3cholenoic acid methyl ester activity in 29:27 3-oxocholest-dihydroxy-cholest4,7-dien-6-one activity in 29:27 313,14c~-4,6,8(14)-triene activity in 29:27 3 [~,7 e-dihydroxychole st- 5-ene activity in 29:27 ( 2 5R/S) 2 0,2 6-dih ydro x yecd yso ne activity in 29:26 20-(2',2'-dimethyl-(22R)furanyl) ecdysone activity in 29:26 6,24-dioxo-3 [3,14t~-dihydroxy513-chol-7-en-24-dimethylamine activity in 29:27 ecdysone activity in 29:26,28 3 [3-ethoxy- 14 ot-hydroxy-5 ~-
cholest-7-en-6-one activity in 29:26 for Bombyx mori pupae's ecdysone 29:25 for Calliphora erythrocephala 29:25 14c~-hydroxy-3c~,5 ~cyclocholest-7-en-6-one activity in 29:27 3-oxo- 14~-hydroxy-5 f3-cholest7-en-6-one activity in 29:26 14~-hydroxy-5 [3-cholest-7-en-6one activity in 29:26 3 [3-hydroxy-5 ~-cholest-7-en-6one activity in 29:26 3 ~-hydroxy-5 [3-cholest-8,14dien-6-one activity in 29:26 ( 14cz-H)3 ~-hydroxy-cho le st-4,7dien-6-one activity in 29:27 14c~-hydroxycholest-4,7-dien3,6- dione activity in 29:27 20-hydroxyecdysone 25-acetate [viticosterone E] activity in 29:26 20-hydroxyecdysone 3-0cinnamate activity in 29:26 22-epi-2O-hydroxy-ecdysone activity in 29:27 20-hydroxyecdysone activity in 29:26 5 ~-hydroxypterosterone activity in 29:26 (25R/S)-inokosterone activity in 29:26 makisterone A activity in 29:26 3 [3-methoxy- 14c~-hydroxy-5 [3cholest-7-en-6-one activity in 29:26 24R-methyl-2 [3,14c~-dihydroxy5~- cholest-7,22-dien-6-one activity in 29:27 3ct-methyl-3 ~, 14c~-dihydroxy5[3- cholest-7-en-6-one activity in 29:26 5 [3-methyl-3 [3,14~-dihyroxycholest-7-en-6-one activity in 29:27 2ct,3 ~, 14ot,20R,22R-pentahyd-
138
roxy-5 [3-cholest-7-en-6-one activity in 29:26 213,313,20R,22R,25-pentahydroxy5 [3-cho 1est- 8,14-di en- 6- one activity in 29:26 polypodine B activity in 29:26 ponasterone A activity in 29:26 poststerone activity in 29:27 2,3-seco-ecdysone activity in 29:27 4-nor-3 [3,14ot,25-trihydroxy-5 [3cholest-7en-6-one activity in 29:27 313,5(x,14c~-trihydroxy-cholest-7en-6-one activity in 29:27 Calliphora erythrocephala 29:25 Calliphora victina 29:31 Callitristic acid 15:172 from Rabdosia kunmingensis 15:172 Callna vulgaris 29:691 Callosobruchus chinensis 21:379; 24:714,715 Callosobruchus maculatus 24:714 Callosobruclus analis 9:299 Callus culture 2:366 growth within 2:366 Callyspongiajohnstorii 25:717 Callyspongia sp. 25:724;28:673 Callyspongia truncata 25:723;28:712 Callyspongin A 28:712 as starfish fertilisation inhibitor 28:712 Callyspongin B 28:712 as starfish fertilisation inhibitor 28:712 Callystatin A 25:724 Calmodulin 1:4,399;22:35;25:706; 26:917,919,920 inhibitor of 25:706 Calmodulin antagonist activity 25:758 Calmodulin domain-containing protein kinase (CDPK) 25:544 Calmodulin inhibitory activity 2:282, 284 Calmodulin kinase III 27:854 Calmodulin-dependentphosphodiesterase (CAM-PDE) 25:509
Calmodulin-dependent phosphodiesterase (CAM-PDE) 25:509 Calmodulin-pathways 26:250 Calocedrus decurrens 28:408 Caloglossa liprieurii 26:478 Calomyrmex sp. 5:223,224,230,253 Calonectrin 6:230,21 ;9:206 deoxynivalenol from 6:230,21 Calonectrin 9:206 Calophylloide 22:542,536 Caloscypha fulgens 7:338 [3,y-carotene from 7:338 Calpurina aurea 7:427;28:400 killing effects on ticks 28:400 Calvin photosynthesis 13:330 Calvularia virdis 25:704 Calycanthoside 7:224 Calyceramide A 28:713 as neuraminidase inhibitors 28:713 Calyceramide B 28:713 as neuraminidase inhibitors 28:713 Calyceramide C 28:713 as neuraminidase inhibitors 28:713 Calycinoxanthon 30:621 structure of 30:621 Calycinum L. 22:656,672 Calycocystis Bunge 27:444 Calycopterin 5:757 Calycosin 27:498,499 Calycotomine 12:449 ent-Calyculin A 26:1234,1235-1239, 1240 total synthesis of 26:1234, 1235-1239,1240 Calyculin A 18:269;27:877,878 as okadaic acid 27:877 Calyculin derivative 25:731 Calyculin J 25:732 Calyculins 5:395,396 Calyculins A-H 26:1204,1205,1240, 1234,1235 Calyculins B&C 26:1240 Calystegia sepium 22:718 Calystegine A3,As-A7 22:184,730 Calystegine BI-B5 22:721 (+)-Calystegine B2 22:734
139 Calystegine Cl,C 2 22:185 Calystegine Nl 22:185 Calysterol 9:38,39,44,45 Calyx nicaeensis 9:37,44 calysterol from 9:38 dihydrocalysterol from 9:37,44 (23R,24 R)-23,24-me thylenecholesterol from 9:37 nicasterol from 9:37 Calyx podatypa 9:38,45;26:64,65 Calyxin A 23:805 Calyxin B 23:805 Calyxin C 23:806 Calyxin D 23:806 Calyxin F 26:902 Calyxin G 26:902 CaM antagonists 25:489,492 CaM dependent kinases 25:543,544 CaM inhibitors 25:491 Camaraside 23:522 Cambogin 22:659 CaM-dependent isoform of PDE (CAM-PDE) 25:490 CaM-dependent PKs I-IV 25:524 CaM-dependent protein kinases 25:493, 527 Camellia japonica 23:404,438 Camellia oleifera 23:406 Camellia sinensis 20:735;21:499; 23:341 ;25:472,478;29:579,582-585, 588,654,655 Camellia sinensis var. sinensis 21:660 Camelliagenine A 21:673 Camelliantannin H 23:405,412 Camelliasaponins 21:675 Camelliatannin D 23:405,438,441 2D J-resolved NMR spectrum of 23:441 structure of 23:438 Camellidin I&II 15:202 Camelliin A 23:404,408 Camelliin B 23:405,411,436 structure of 23:436 Camelliins 23:407 Camellioferin A 23:405 Camelspin 6:140 (-)-Camoensidine 15:520 Camomile 13:660
cAMP 30:192 in regulation of ionotropic receptors 30:192 cAMP formation 30:383 G-protein inhibition 383 cAMP-dependent channels 25:495 cAMP-dependent protein kinase (PKA) 25:488,489,522,547,548 cAMP-dependent protein phosphorylation 25:494 Campestanyl ferulate 9:474 Campesterol 9:454,129,520;20:234; 22:482;30:505 Campesteryl linoleate 9:461 cAMP-gated Na § channels 25:517,523, 524,546 Camphanate method 6:153 (1S)-Camphanic acid 14:179 S-Camphanic acid 16:478 (1S)-(-)-Camphanic chloride 18:607, 613,627 Camphene 21:598,601 (-)-Campherenol 4:675 Campherenone 16:136 enantiospecific synthesis of 16:136 (-)-Campherenone 4:675 (-)-c~-Campholenic acid 16:125,127,148 (+)-Camphor 10:408,123-124 radioimmunoassay of 7:114,115 (-)-Camphor 10:52,123-124 d-Camphor 11:6,7 (+)-Camphor 19:229;20:586 Camphor 7:95;9:530,536;16:123,124; 20:16;25:125,128,154,156,547; 27:376 D-(+)-Camphor 25:156 Camphor enol trimethyl silyl ether 4:656,657,665 Camphor sulfonic acid (CSA) 30:6 (-)-Camphor-10-sulfonate 16:125 D-Camphor-10-sulphonic acid 4:628, 632;19:139 Camphor-10-sulphonyl bromide 4:628, 629 thermolysis of 4:628,629 m-and p-Camphorene 15:227 from Eremophila cuneifolia 15:227
140 Camphorene 5:127,696 Camphoric acid 20:586,597 Camphorquinone 4:660,661,666,149(-)Camphorquinone rearrangement 16:150 (-)-Camphorsulfonic acid 12:417 (+)-10-Camphorsulfonic acid 15:425 Camphorsulfonic acid 6:68,221,205 cAMP-induced Ca2+-influx 25:491 cAMP-induced influx 25:497 of K + 25:497 Campnospermanol 9:323,329 Campnospermum auriculata 9:323 S-Campothecin 16:431 asymmetric synthesis of 16:431 cAMP-phosphodiesterase 25:539 cAMP-response element binding (CREB) 25:523,548 cAMP-sensitive ion channels 25:490, 496,497 Camptotheca acuminata 23:405;24:269; 26:144 (+)-Camptothecin 18:333,349,355 rad52-Camptothecin 20:465 Camptothecin 5:84,85,127;12:283; 13:654 ;20:500;22:28 as anticancer agent 13:654 from Camptotheca acuminata 13:654 synthesis of 12:283 Camptothecine 26:825,827 Camptothecine-type alkaloids 5:84,85 Camptothin A 23:405 Camptothin B 23:405 Campylosporus hypericin 30:609,610 Campylotorpis hirtella 25:94 Canabichromene 4:398,399 synthesis of 4:398,399 from Cannabis sativa 4:398 Canadensene 20:107 Canadensolide 19:463 (-)-Canadensolide 19:485 (R)-(+)-Canadine 10:678 Canadine 21:96 (+)-Canadine 6:489,490 Canadine methiodide 6:491,492 allocryptopine from 6:491,492 cis (trans)-Canadine N-oxide 6:474,475 nitrone from 6:474,475
trans-Canadine N-oxide 6:474,488,489 cleavage product of 6:488,489 photolysis of 6:474 Canagana sinica 27:855 Canaliculatol 23:53,547;26:562 Canavalia gladiata 25:93;29:598 Canavalia lineata 29:598,603,604,607 Canavaline 20:486;26:932 Cancer 17:137;24:404,405;30:55,56, 58,224,732 Aresch. in 30:56 epidemiology of 24:404-405 Ganoderman lucidum in treatment 30:58 prevention of 30:56 role of free radicals 30:224 role of natural products in 30:55 treatment of 30:56 use of Laminaria japonica Cancer cell lines 30:588 cytotoxicity against 30:588 Cancer cell lines inhibition 27:916-918 by biflavonoids 27:916-918 by chalcones 27:913-916 by flavanones 27:908-912 by flavones 27:897,898,899-903 by flavonols 27:903-908 by isoflavones 27:912-913 by 1,2-diphhenylpropane derivatives 27:920-921 by 1,3-diphenylpropane derivatives 27:919-920 Cancer chemoprevention/anti-inflammatory bioassay 29:75;30:588,591 for anti-inflammatory activities 29:76 for anti-mutagenic activity 29:75 for apoptosis induction 29:79 for cancer chemopreventive activity 29:76 for COX-2 iNOS inhibition 29:79 for GSH induction 29:78 for GST formation 29:78 for inhibition of active oxygen species formation 29:78 for inhibition of tumor promotion 29:77 for NF-KB inhibition 29:80
141 for ODC inhibition 29:79 for PKC inhibition 29:80 for TNF-ot inhibition 29:80 Hernandia species for 588 replication initiation in 29:75 Cancer chemopreventive activity 26:507,508,510,511 ;30:591 in rat mammary carcinogenesis model 30:592 in two-stage mouse skin 30:591 Cancer chemopreventive agent 30:591, 593 from Hernandia species 30:593 in vitro 30:593 activity in mouse mammary organ culture assay 30:593 activity in mouse skin carcinogenesis test 30:593 Cancer chemopreventive agents 24:1061-1062;25:43 Cancer chemotherapy 4:544;24:403464;28:559;30:56,64,841 by substituted benzo [c]phenanthridines 4:544 cisplatin for 28:559;30:56 doxorubicin 30:56 famesyl-protein transferase for 24:403-464 side effects of 30:56 Cancer chemotherapy drug 28:559 as doxorubicin 28:559 Cancer growth inhibition 23:290,292 by bruceanol D 23:290,292 ofbruceanol E 23:290,292 ofbruceanol F 23:290 Cancer prevention 30:762 due to green algae 30:762 Cancer related activity 21:634 Cancer target 30:591 chemopreventive drugs as 30:591 Cancerostatic activity 26:452 Cancer-preventing activity 21:641 Candicin 15:328 Candida albicans 2:422,428,438-440, 292,5:233,282,323,324,342,356,369, 400;7:282;19:578;20:712;21:232, 235,237,608,611,662;22:57,61,74, 79,248,299,398,627,628;23:10,114,
123,164,235,335,347 ;25:258,759, 764,773,780,790,822;26:228,402, 403,673,1093,1124,1126,1134,1187, 1203,1216,1217;28:686;29:571,751; 30:739 antibacterial activity against 30:739 antifungal activity against 30:739 Batzella sponge against 28:685 Candida albicans 1463D 28:476 Candida albicans ATCC 90028 28:476 Candida albicans ATCC 90029 28:476 Candida bogoriensis 5:294 Candida boidinii 22:601 Candida curvata 5:292 Candida cylindracea 12:337;18:429 Candida dubliniensis CBS 7987 28:476 Candida genus 29:328 Candida glabrata 22:57;26:1126 Candida guillermondii 2:422;22:57; 26:1126 Candida humicola 5:292 Candida kefyr IFM 46921 28:476 Candida krusei 12:400;22:57;23:115 Candida lipolytica 5:292,308 Candida lusitaniae 5:283 Candida neoformans 22:57 Candida obtusas 5:283,292 Candida parapsilosis 5:292,323,324; 22:57;28:476 Candida patens 2:441 Candida pellicula 25:308 Candida pseudotropicalis 12:400 Candida rugosa 1:694,306 Candida sp. 5:291,292,328;21:192,232, 758;22:248;26.330,331,1087,1126, 1127,1134 Candida tropicalis 2:422,400;22:57 Candida tropicalis IFM 46816 28:476 Candida utilis 7:69,302,235;21:608,611 Candida valida 26:1091 Candidiasis 2:332,425,432;6:261 polyene macrolides in 6:261 Candidissimus 26:457 Candidissiol 20:680 from Salvia candidissima 20:680 Candidoses 6:261 polyene macrolides in 6:261
142 Candsburgia quercifolium 29:722 Canella winterana 2:447 Canellaceae 7:427;17:234 Canellal 2:447,448 Cangorinin 18:760 Cangoronine 23:695 Cangorosa 23:657 Cangorosin B 18:665;30:683 ROESY of 30:683 CD spectral data of 30:683 FAB-MS of 30:683 10-epi-Canin 27:576 Canin 7:234 Canin-8~-isovalerate 27:576 Canin-8ct-methyl butyrate 27:576 Canine-hysteria 7:6 Canna indica 28:425 Cannabidiol 22:538,515 (-)-trans-Cannabidiol dimethyl ether 19:187 Cannabifuran 19:194 Cannabinaceae 30:610 acylphloroglucinols from 30:610 Cannabinoids 19:185-244;30:193,194, 195 anti-nociceptive 194 as analgesic 30:195 anti-nociceptive effects of 30:193 from Cannabis sativa 30:195 role in neuronal excitability 30:194 structure-activity relationships (SAR) of 30:195 Cannabinoid affinity 30:196 for CB2 receptor 30:196 Cannabinoid antagonist 30:198 development of 30:198 Cannabinoid receptor 19:186;30:194 in central nervous system 30:194 in peripheral nervous system 30:194 Cannabinoid receptor (CBl) 19:186 Cannabinoid skeleton 19:186 retrosynthetic disconnection of 19:186 Cannabis 7:7 Cannabis sativa 19:186;22:515;25:532; 30:194,198
as analgesic 30:194 as intoxicant 19:186 as natural therapeutic herb 30:194 cannabinoids from 30:194 therapeutic use of 30:198 (-)-Cannabisativine 16:492-493 synthesis of 16:492-493 (-)-Cannibidiol 16:131 Cannizzaro reduction 19:536 Cannobinoid receptors 25:533 Canophyllol 5:744,748,750;23:702 Canscora decussata 22:515 for epilepsy 22:515 Cantabradienoic acid 7:216,238 from Artemisia cantabrica 7:216,238 Cantaxanthin 21:305 Cantharellus cibarius 5:289;23:343 Cantharellus cinnabarinus 20:721 Cantharidin 26:457 Cantharis vesicatoria 27:882 Canthaxanthin 20:576,725,749;30:520, 536,540,543,544,546 ID/2D ESEEM techniques for 30:540 stretching vibrations in 30:540 studies on 30:536 UV irradiation of 30:540 Canthaxanthin cation radical 30:536, 540 ENDOR spectrum of 30:540 EPR data of 30:540 structures of 30:536 Canthigaster solandri 21:364 Canthin alkaloids 24:282 Canthin-6-one 7:389,390,394 Canthium bibracteatum 22:515 for convulsions in children 22:515 Canthium gueinzii 22:515 for epilepsy 22:515 Cantleyinde derived alkaloids 6:527 Cantleyine 6:503,527,529 from Strychnos muxvomica 6:503,527,529 Cantleyine series 6:522 Cantoniensistriol 25:96
143
Canventol 29:111 activity in skin-5 bioassay system 29:111 activity in RAS bioassay system 29:111 activity in TNF~ bioassay system 29:111 Capal 23:659 Capalliferol A 548 Capellene-8 [3,10a-diol 3:63 Capillanol 7:222 Capillarin 7:202,203,223 Capillene 7:202-204,222 Capnella imbricata 22:209 Ag~Z)-capnellene from 13:34 capnellanes from 6:42 precapnelladiene from 6:33 Capnellanes 6:42 from Capnella imbricata 6:42 from (-)-A9~lZ)-capnellene 6:42 synthesis of 4:588 Capnellen-3[3,8[3,10c~- triol 3:63,64 Capnellene 3:11,13,19,20,22;22:195, 209,215,217 synthesis of 3:11,13,19,20,22 A8/~9)-Capnellene 3:20 synthesis of 3:20 A9<12)-Capnellene 3:7;13:34,35 synthesis of 13:34,35 from Capnella imbricata 13:34, 35 (-)-Ag~12)-Capnellene 6:42 capnellanes from 6:42 (+)-A9~12)-Capnellene 6:45 by ~x-alkaynone cyclization 6:45 by [2+2] cycloaddition reaction 6:43,44 by [4+2] cycloaddition reaction 6:43,44 by cyclopropane sliding reaction 6:48 by Diels-Alder reaction 6:46 by intramolecular alkylation 6:42,43 by intramolecular diyl trapping reaction 6:46 by intramolecular reductive coupling 6:48
by intramolecular type I Mg ene reaction 6:45,46 by methylenation 6:46,47 by 1,2-methyl shift 6:48 by Nazarov cyclization 6:43 by photochemical annulation 6:48 by three-carbon annulation 6:42 Dreiding synthesis of 6:45 from [3-diketone 6:48 from humulene 6:48 Grubb synthesis of 6:46,47 Liu-Kulkarni synthesis of 6:43,44 Oppolzer-Batting synthesis of 6:45,46 Stille synthesis of 6:47 synthesis of 6:42,43 with Tebbe reagent 6:46,47 A 9(m2)-Capnellene 213,813,10a-triol 3:7 A9(lZ)-Capnellene-3[3,813,10c~-triol 3:7 A 9(12) -Capnellene 313,813,10c~-triol 22:209 Capnellene-2[3,8[3,10c~-triol 3:64 Capnellene-3[3,8[3,10c~-14- tetriol 3:64 A 9(12)-Capnellene-3[3,813,10[3-14-tetrol 3:7 Capnellene-5c~,8[3,10c~-triol 3:64 Ag(~2)-Capnellene-5c~,813,10c~-triol 3:7 A9112)-Capnellene-8[3,10c~-diol 3:7 Capnellenols 6:49,50 by aldol cyclization 6:49,50 by three-carbon annulations 6:49,50 synthesis of 6:48-50 Caporal 22:67 Capparis baducca 22:515 Capparis decidua 9:73-75,77 alkaloids from 9:73-75,77 Capparis masaikai Levl. 27:18 mabinlin from 27:18 Capparisine 9:73 Capping reaction 4:279,280 in oligonucleotide synthesis 4:279,280 Capraria biflora 15:259 Capreomycin 2:424 Capric acid 21:595
144 Caprifoliaceae 7:427;25:249,251,259 Capsaicin 7:93;27:747,749;28:436,437; 30:195,201,202,206 as complex I inhibitor 28:436, 437 activity of 30:202 antinociceptive action of 30:206 as natural analgesic product 30:195 as vanilloid receptor agonist 30:202 effect on TRPVI expression 30:206 from Capsicum sp. 7:93 inhibition of NO production by 30:201 Capsaicin analogue 30:193,201 olvanil as 30:193 SDZ 249-665 as 30:193 structure-activity requirements of 30:201 Capsaicin induced edema 25:46 inhibition of 25:46 Capsaicin receptor 30:201 lipophilic part of 30:201 Capsaicine 21:89 Capsanthin 20:726,733,757 Capsazepine 30:201,202 as vanilloid receptor antagonist 30:201,202 effect on iNOS protein synthesis 30:201 nitric oxide inhibition by 30:201 Capsicum annuum 13:320;20:586; 29:610 Capsicum frutescens 20:135 Capsicum sp. 28:400,436;30:193 capsaicin from 7:93 Capsicum species 28:436,400 killing effects of ticks 28:400 Capsid proteins 24:477-479 enzymes of 24:478,479 Capsimycin 23:51;28:138 antifungal activity of 28:138 Capsorubin 20:568,586,726,77 Capulin 22:559 (+)-Capuronidine 5:126 Capuronine 5:124 20R-Capuvosidine 5:125
Capuvosine 5:129 Caraganaphenol A 26:535,563 Caralluma tuberculata 5:212;9:62-64 saponins from 5:212;9:62-64 Carapa abovaa 7:189 Carassius carassius 21:364 Caratuberside A 5:212,213 Caratuberside A-D 9:62-64 Caratuberside B 5:213 Carausius morosus 9:492 5a-Carba -c~-D-glucopyranosylamine cis-2,3,4 trihydroxy-5 (hydroxymethyl) 1-cyclohexylamine] 13:195 Carbaaldofuranoses 29:452 synthetic strategies for 29:452 target-oriented (linear) synthesis of 29:452 Carbaaldopyranoses synthesis 29:467 building-block for 29:469 by Angelaud and Landais 29:467 by Btichi and Powell 29:472 by Emmons-Horner-Wadsworth 29:471 by furan-based Diels-Alder approach 29:470 by Metha and Mohal 29:470 by microbial transformations 29:469 by Sudha and Nagarajan 29:472 by Toyokuni 29:471 by Zanardi and co-workers 29:473 chiral sources for 29:467 conditions for 29:468 diastereoselective routes to 29:471 exploitation of natural carbohydrates for 29:471 ofglycosidase inhibitors 29:467 Carbacepham 8:262;12:121 synthesis of 12:121 Carbachol 25:613;26:267 Carbacyclins 16:388 Carba-disaccharides 13:219-221 synthesis of 13:219-221 Carba-DL-hexopyranose 13:1875aCarbafuranose synthesis 29:452 by agrofoglio 29:461 by D6sir6 and Prandi 29:455
145 by Lowary and Callam 29:457 by Lundt and Horneman 29:456 by Metha and Mohal 29:462 by Monti 29:458 by Rassu 29:453 conditions for 29:453 from c/s-fused bicyclic furanone 29:452 of 2 C-methyl-4c~-carba-[3-Darabinoaldofuranose 29:459 of 2 C-methyl-4o~-carba-~3-Dlyxoaldofuranose 29:459 of 4 ~-carba-ct-D-xylofuranose 29:452 starting from norborn-5-en-2-one 29:452 Carbafuranoses 29:451 aminocarbafuranoses as 29:452 as bioactive compounds 29:451 carbaketofuranoses as 29:452 carbocyclic analogues of 29:451 carbocyclic nucleosides as 29:451 conjugates of 29:451 thiocarbafuranoses as 29:452 unsaturated 29:452 Carbafuranoses 29:451 diversity-oriented synthesis of 29:451 5a-Carba-glycosylamines 13:195-204 synthesis of 13:195-204 5a-Carba-hexopyranoses 13:190-207 synthesis of 13:190-207 Carbaketofuranose synthesis 29:460 by A1-Abed and Seepersaud 29:460 by Wilcox and Gaudino 29:460, 461 conditions for 29:460 Carbaketopyranoses 29:474 as sweeteners 29:474 ketose-type pyranoses as 29:474 stereoconstitutional features of 29:474 5-Carba-levoglucosenone 14:279 1,4-exo-aducts of 14:279 3-deoxy derivative of 14:279 synthesis of 14:279
Carbamate ester 21:168 Carbamazepine 22:507 Carbamoylmethylviologen 20:867,869 Carbanion 16:30 Carbanion reagents 11:439-443 Carbanion rearrangement 16:620 Carbanions 1:351-353 Carbaoctanoses 29:502 functional groups in 29:31 stereocentres in 29:502 Carbaoxirose/carbaoxetoses 29:490 1-deoxy- 1-amino-6(~-c arba- [3-Dglycero-D-gulcoheptoseptanose as 29:495 6cz-carba-[3-D-glycero-Dgulcoheptoseptanose as 29:494 against hepatitis B virus 29:493 against herpes viruses 29:491 against HIV 29:491 as glucosidase inhibitor 29:497 asymmetric synthesis of 29:490 calystegine B2 as 29:496 enantioselective synthesis of 29:492 in cytomegalovirus infections 29:492 synthesis by Boyer and Hanna 29:497 synthesis by Ichikawa 29:492 synthesis by Skaanderup and Madsen 29:496 Carbapenams 8:262,263 synthesis of 8:262,263 Carbapenem 4:434 as asparenomycins 4:434 as carpetimycins 4:434 as KA-antibiotics 4:434 as nor-thienamycin 4:434 as OA-antibiotics 4:434 as pharmacophore 4:434 as pluradomycins 4:434 Carbapenem antibiotics 13:495-507 (+)-6a-Carbaprostaglandin I2 1:698,699 synthesis of 1:698,699 Carbaseptanoses 29:493 total synthesis of 29:493 Carbasugars (alias pseudosugars) 13:187-255;29:449,507
146
analogues of 29:506 basic motif of 29:449 biological effects of 29:449 categories of 29:449 chirality in 29:449 cyclobutane cores of 29:449 cycloheptane cores of 29:449 cyclohexane (pyranoid) motif of 29:449 cyclooctane cores of 29:449 cyclopentane (furanoid) motif of 29:449 cyclopropane motif of 29:449 reviews about 29:506 synthesis of 13:187-255;29:449, 507 Carbazolequinone alkaloid 1:163 5a-Carba-ot-D-galactopyrano se 13:187,191 5a-Carba-ot-D-glucopyranose 13:188, 215,219 5a-Carba-et-D-glucosamine 13:210,212 5a-Carba-ot-DL-galactopyranose pentaacetate 13:188 5a-Carba-ct-D-mannopyranose 13:216 4o~-Carba-ot-D-xylofuranose 29:452 carbafuranose synthesis of 29:452 5a-Carba- [3-DL-mannopyranose derivative 13:191 Carbendazein B 25:6772 Carbendazime 22:462;25:669 Carbene complexes 16:406 Carbene insertion reaction 4:436,438 Carbene-diene cyclization 3:29 Carbene-olefin cyclization 3:325 Carbenoid displacement 1:259 Carbenoid insertion 13:501-503 Carbenoxolone 22:425 (E)-[3-Carbethoxyacroylyl chloride 14:560 Carbethoxycyclohexanone 14:745 isonitramine from 14:745 nitramine from 14:746 Carbinolamides 4:57 Carbinolamine 4:57,269,270
Carboalumination 1:454,455,459 with Me3A1, ZrCp2C12 1:454, 455,459 N-Carboamoyl-Gly-IA human insulin 2:38-41 HPLC of pepsin digest 2:38,39 peptides by LSIMS 2:38-41 structure of 2:37-39 N-Carbobenzyloxyslaframine 12:308 Carbocation intermediate 6:474 in 2,5-benzoxazonines syntheses 6:474 Carbocupration reaction 14:507,508 asymmetric induction in 14:507, 508 diastereoselective 14:507,508 of C2-homochiral cyclopropenes 14:507,508 Carbocycles 8:272 from palladium (+2) complexes 8:272 Carbocyclic nucleoside 8:148 antibiotic activity of 8:148 antitumor activity of 8:148 antiviral activity of 8:148 Carbocyclic oxetanocin A,G 10:620, 621 antiviral activity of 10:620,621 Carbocyclic oxetanocins 10:608-619 synthesis of 10:608-619 Carbocyclic spiro compounds 14:544-546 asymmetric synthesis of 14:544-546 2-Carboethoxy-2-deoxy-2-ulosoic acid esters 30:467 decarboxylation of 30:467 6-Carboethoxyolivetol 4:386,387 with geranyl bromide 4:386,387 Carbohydrate derivative 14:659-664 synthesis of 14:659-664 via Norrish type II reaction 14:659-664 Carbohydrate lactones 10:385 C-glycosides from 10:385 Carbohydrate transporting proteins 7:29 Carbohydrate-molybdate complexes 15:426-435 4-Carbohydroxypatchoulol 25:172
147 [3-Carbolines 23:260,261,266;25:33, 782,902 biosynthetic studies of 23:260, 266 fl-Carboline alkaloid eudistomidins 25:817 [3-Carboline alkaloids 2:369,90 13-Carboline derivative 8:285;25:10,14 ~-Carboline marine alkaloids 25:819 fl-Carboline metabolites 25:818 ~-Carbolines 5:414,415,417,245 [3-Carbolines 5:417,418;21:84 Carbomanoyl oxide 25:261 (+)-Carbomenthone 6:547,548 Robinson annulation of 6:547, 548 2-Carbomethoxycycloheptanone 12:241 with 4-bromobutyraldehyde dimethyl acetate 12:241 dl-Carbomethoxydihydrocleavamine 14:806,807,850-853 Carbomethoxylation 4:36,38 of ketone 4:36,38 Carbomycin 13 10:170 Carbomycins 11:164 Carbon catabolite 25:313 Carbon tetrachloride 25:460 Carbon versus oxygen alkylation 4:367 regioselectivity of 4:367 Carbon-bridged system 12:87 Carbonimidic dichlorides 21:346 Carbonimidoyl dichloride 21:356 Carbonolide B 11:162-166 Carbonolides 11:163-172 stereoselective synthesis of 11:163-172 synthesis of 11:158-172 Carbon-tin bond 1:352,353 conversion to carbon-silicon bond 1:352,353 Carbonyl coupling reaction 8:16-18 titanium induced 8:16-18 Carbonyl reduction 1:622 diastereoselective 1:622 of ~-keto acetals 1:622 Carbonyl tosylhydrazone 30:32 reductive deoxygenation of 30:32
1,2-Carbonyl transposition 3:474,485 1,3-N-Carbonyl-3'-deoxygentamycin X: 14:146;16:432 Carbonylation 19:189,195 palladium catalyzed 19:189,195 N,N'-Carbonyldiimidazole 1:268;4:327 1,1'-Carbonyldiimidazole 8:90;22:291 Carbopalladation 16:374 (-)-Carbovir 10:608,609 antiviral activity of 10:608,609 20-Carboxaldehyde 19:471 3-Carboxamido analogue 30:198,199 of cyclazosine 30:198 structure of 30:199 2S-Carboxy-3R,4R,5S-trihydroxy piperidine 10:549 absolute configuration of 10:549 from Baphia racemosa 10:549 relative configuration of 10:549 Carboxyatractyloside 20:8 3-Carboxy-cis, cis-muconate 8:305 cycloisomerisation 8:305 3-Carboxy-cis, cis-muconic acid 8:295, 296,306 3-Carboxycoumarin 18:978 6-Carboxydihydrochelerythrine 27:167 4'-Carboxyl group 27:330 for photoaffinity 27:330 1-Carboxyl group 27:354 for abscisic acid bioactivity 27:354 (4S)-3-Carboxylactone 8:297 Carboxylation 11:195 (2S)-methylmalonyl CoA by 11:195 of propionyl CoA 11:195 Carboxylic acid 2:4;30:23 debenzylation of 30:23 oxidation of 30:23 Carboxylic acid anhydride variation 4:375 of Claisen condensation 4:375 Carboxylic acid silyl esters 4:564 with silylated phosphonium ylides 4:564 Carboxylic esters 6:334 into aldehydes 6:334 synthesis of 6:326327 8-Carboxylinalool 25:140
148
5-Carboxymellein 15:383 Carboxymethyl glucan (CMG) 23:139 2-Carboxymethyl-3-hexyl maleic acid 21:240 Carboxymethyllated grifolan (CMGRN) 23:140 4-Carboxymuconolactone $:295,296 Carboxypeptidase 9:489;25:375 Carbylamine reaction 12:113 isocyanides by 12:113 Carcinoembryonic antigen (CEA) 29:552 as tumor antigen 29:552 in colorectal cancer 29:552 periodate oxidation of 29:552 Carcinogen 21:97;24:1061,1062; 24:1061,1062;26:1002-1004 HA as 26:1002-1004 Carcinogen MNU 25:66 Carcinogenesis 20:512,513;26:965; 30:524,591,592,762 DMBA 30:762 in experimental animals 30:591 in mammalian cells 30:592 inhibition of 30:591 initiation of 30:592 natural inhibitors of 30:591 progression phases of 30:592 promotion of 30:592 Carcinogenesis research 15:439 Carcinogenic activity 13:532 of fumonisins 13:532 Carcinogenic study 27:306 of stevioside 27:306 Carcinogenicity 7:8,9;26:677;27:302 ofbenzo [1] pyrene 7:8,9 of madder root 26:677 Carcinoid cells 27:797,844 Carcinoma Ehrlich cells 25:836 Carcinomycin 1:498 Carcinus maenas 19:628;25:718 Carcurine 25:528 as immunosuppressive drug 25:528 Cardamine pratensis L. 22:515 for epilepsy 22:515 Cardamonin 23:808,821,802 Cardanol monoene 30:152 skin irritancy due to 30:152
Cardanols 9:313-315,323,326,330,332, 333,335-338,340,341,349,352,358, 363,368-371 ;21:592;30:150-152 biological properties of 30:150-152 [3-Cardene 25:944 Cardenolides 24:289;25:535;30:691 cytotoxic activity of 30:691 against KB cell line 30:691 Cardiac activity 21:98,669 Cardiac depressant 5:750 Cardiac diseases 30:224 role of free radicals in 30:224 Cardiac glycosides 9:293;21:89 Cardiac steroid 25:55,59 Cardiac toxicity 21:158 Cardiopetamine 26:868,869 Cardiotonic 23:499;24:898 aconitine as 24:898 Bacopa monnieri as 499 Cardiotonic activities 21:501 Cardiotonic constituent 17:33 Cardiotonic peptides 5:403 Cardiotonicity 24:875 as biological action 24:875 Cardiovascular activity 21:668 Cardiovascular disease 23:739;30:155, 524 Ginkgoaceae against 30:155 incidence of 30:524 Cardiovascular effects 26:232 Cardiovascular hypertrophy 26:236 Cardiovascular modulating effects 26:507-509 Cardiovascular system 26:183 effect of Schisandra on 26:183 Cardnol methylether 9:338 by azonolysis 9:338 Cardols 9:315,318,324,328,332,333, 335-339,341,347,349,358,359,368, 370;21:592;26:443 ;30:146 by decarboxylation 30:146 Cardwellia sublimis 9:320 Cardyceptin (3'-deoxyadexosin) 24:547 antiviral microbial-derived compound 24:547 Careaborin 7:189 (+)-Carene 12:243 A3-Carene 21:582
149
(+)-trans-Carene epoxide 19:204 Carex kobomugi 26:530 Carex pumila 26:551 (-)-c-viniferin from 26:551 Caribbean collection 28:632 minalemines D from 28:632 minalemines F from 28:632 Caribbean coral 25:690 Caribbean gorgonian 29:103 Caribbean sponge 25:698 Carica papaya 29:592,604 Caries 27:316 Carimbia subgenus 24:233 Carinogenesis 9:583 Carissa edulis 20:619 Carmenin 7:236 Carminative agent 23:642 of Teucrium sp. 23:642 Carminomycin 4:317 Carminomycinone 14:20 (S)-(-)-Carnegine 10:677,679 (R)-(+)-Carnegine 10:677,679,682 Carnegine 21:84 Carnitine palmitoyl transferase (CPT) activity 21:458 Carnosic acid 21:618;29:188 activity against HIV- 1 protease 29:190 antioxidant activities of 29:188 biological activity of 29:188 Carnosic acid synthesis 29:191 by Banerjee et al. 29:194 by Meyer et al. 29:191 by Tiam et al. 29:198 starting material for 29:191 Carnosifloside V 27:14,25,26 structure of 27:26 Carnosifloside VI 27:14,25 structure of 27:26 Carnosol 29:99,574 activity in DNA assay system 29:99 activity in mam-2 assay system 29:99 activity in skin-1 assay system 29:99 activity in NFkB assay system 29:99 activity in iNOS assay system
29:99 activity in NO assay system 29:99 activity in GST assay system 29:99 activity in CYP assay system 29:99 effects on HIV- 1 protease 29:574 Carnosolic acid 29:575 7-O-Methylrosmanol (abietane diterpene) synthesis from 29:575 rosmanol (abietane diterpene) synthesis from 29:575 Carob galactomannan 26:1139,1149 Carolisterol A-C 15:76;25:872 from Styracaster caroli 15:76 Carotadiol esters 5:725.727 Carotan lactone 5:725,726 Carotenal 30:546 (6'R)-13,~-Carotene 20:584 s-Carotene 20:584,721,725;26:299,300 ~3-Carotene 4:559,560;7:20,98,318, 319,334-342,344;17:611,612,708; 20:720,721,725,732,735, 746-748,760;21:304 ;24:215264;25:236;26:299,300,305;30:516,5 20,524,537,539-544,546,548 absorption spectra of 30:539 as electron donor 30:537 charge delocalisation in 30:544 charge distribution of 30:542 clinical use of 30:524 downfield shifts of 30:544 electrolysis of 30:541 in PS2 30:537 NMR analysis of 30:543 protonation of 30:546,548 role of 30:537 structure of 30:516 UV irradiation of 30:540 T-Carotene 7:327-329,333,334,338; 20:721,725 ~,~-Carotene 20:561,564,571,572, 576,584,604,607;23:179 (9Z,9'Z)-T-Carotene 7:332 from (15Z,9Z)-phytofluene
150
7:332 (9Z,7'Z,9'Z)-neurosporene from 7:332 Carotene 7:333,334,337,3526e-Carotene 7:338 (6S,6'S)-e,e carotene 7:338 from Ulua lactuca 7:338 (1R, l'R)-[3-Carotene 7:344 [3-Carotene anion radical 30:550 [3-Carotene dication 30:519,542,543, 545 by 2D ROESY 30:543 by COSY 30:543 by HMBC 30:543 by HSQC 30:543 by 1D NMR 30:543 reactions of 30:545 structure of 30:519 with water 30:545 B-Carotene hydrolase 25:718 [3-Carotene radical cation 30:519,535, 536,537 studies of 30:537 FT-IR of 30:537 ENDOR of 30:537 EPR of 30:537,539 NIR data of 30:539 spectroscopy of 30:537 structure of 30:536 Carotenoid 5,6-epoxides 6:142 Carotenoid anions 30:548,550 hypsochromic shifts in 30:550 radicals anion of 30:550 Carotenoid biosynthesis 7:317-367 Carotenoid carboxylic acids 30:528,529 examples of 30:528 reactions of 30:529 Carotenoid cation radical 30:521, 534-536,538,540,541 characterisation of 30:538 electrochemical properties of 30:541 electronic absorption of 30:538 orientation of 30:540 spectroscopic methods for 30:538 spectroscopic properties of 30:541
theoretical calculations of 30:534-536 use of electron nuclear double resonance spectroscopy (ENDOR) 30:538 use of electron paramagnetic resonance spectroscopy (EPR) 30:538 use of near infrared spectroscopy (NIR) 30:538 use of Raman spectroscopy 30:538 Carotenoid dianions 30:541,543,544, 548 characterisation of 30:543 effect of electrolytes 30:544 effect of temperature 30:544 preparation of 30:543 properties of 30:544 reactions of 30:544 theoretical calculations of 30:541,548 Carotenoid intermediate 4:676 Carotenoid monocations 30:546 theoretical calculations of 30:546 Carotenoid oxonium ions 30:530 Carotenoid phosphates 30:529 Carotenoid radical cations 30:524 Carotenoid sulphate 30:524,526,527 column chromatography of 30:527 field desorption MS of 30:527 1H-NMR spectra of 30:527 IR absorption of 30:527 negative mode FA of 30:527 partial synthesis of 30:527 reverse phase HPLC of 30:527 solubility properties of 30:527 sulphur analysis of 30:527 TLC of 30:527 Carotenoid-5,6-epoxides 30:530,531 colour test for 30:530 reaction mechanism of 30:531 Carotenoids 4:559;5:370,11,133-169, 150,73;7:321,318-321,329;9:559, 583 ;20:561,725,732,745 ;21:305; 23:178;24:216,533-540;25:44,237; 30:516-518,520,521-523,525,526,
151
537,541,516-518,520,521-523,525, 526,537,541 antioxidant action of 30:516 antioxidant properties of 30:525 application of 30:518 as antiviral compound 24:533-540 as protectors 30:522 by photoexcitation 30:537 cis-trans isomerisation of 30:541 de novo 30:518 electrochemical data of 30:537 from fungi 30:518 from phototropic bacteria 30:518 from phytoplankton 30:518 from termeric pigments 24:216 from yeasts 30:518 from [3-carotene 30:516 functions of 30:520 in light harvesting 30:521 in photoprotection 30:521,526 in photosynthesis 30:516,521 in xanthophyll cycle 30:521 mechanism of 30:522 role in camouflage 30:523 role in colour 30:523 role in phototaxis 30:523 role in phototropism 30:523 role in precursor 30:523 role in reproduction 30:523 role ofneoxanthin 30:523 use of cyclic voltammetry (CV) 30:537 with charged functional groups 30:526 Carotenols 6:150 carotenoid sulfates from 6:150 Carotenoprotein crustacyanin 30:518 Carotenoproteins 6:161,162,317;30:533 from crustacyanin 30:533 (+)-Carotol 14:356 Carotol 5:721,725,731,732,734,737 Carotol triol 5:730 Carp (Cyprinus carpio L.) 28:564;30:64 antitumor activity of 28:564 as diuretic 28:564;30:64 as tonic 30:64 for eye fatigue 28:564 use in eye fatigue 30:64
Carp extract 27:439 antitumor effect of 27:439 of gastrointestinal toxicity 27:439 of myelotoxicity 27:439 prevention of 27:439 Carp oil 28:566;30:55,56,64,65,68,69 antimetastatic activity of 30:56, 64,66 anti-tumor activity of 28:560; 30:64 components of 30:65 DHA from 30:65 effect on liver metastasis 30:55 effect on matrigel-induced angiogenesis 30:68 effect on tumor growth 30:55 EPA from 30:65 fatty acid from 30:65 in vivo 30:68 linoleic acid from 30:65 myristic acid from 30:65 oleic acid from 30:65 palmitic acid from 30:65 palmitoleic acid from 30:65 stearic acid from 30:65 use in tumor prevention 30:64 Carpalasionin 15:174 from Rabdosia rugosa 15:174 Carpesium divaricatum 29:89 Carpetimycins 4:434,135;12:135 Carpinus cordata 17:369 Carpinus sp. 17:369 Carpophilus hemipterus 29:282,292 ~-Carrageenan 30:412 1-Carrageenan 120 Carrageenan foot edema test 30:744 Carrageenan induced edema 25:46,220 inhibition of 25:46 Carrageenan induced paw edema 30:744 Carrageenans 30:399,402 mode of action of 30:402 7-Carrageenans 30:406 inhibitory effect of 30:406 K-Carrageenans 30:406 inhibitory effect of 30:406 Carrol conditions 6:122
152 Carrol rearrangement 10:58,60 Carrol-Claisen rearrangement 6:417 Carrot phytocystatin EIP 18 29:592 effects on chymopapain 29:592 effects on chymotrypsin, papain 29:592 effects on papain 29:592 Carssulaceae 21:737 Carthamus lanatus 14:450,451 eudesm-11-en-4-ols from 14:450 intermedeol from 14:450,451 Carthamus tinctorius 26:436 " Caruifolins (germacranolide sesquiterpene) 29:574 effects on HIV- 1 protease 29:574 Carum carvi L. 22:515 as anticonvulsant agent 22:515 Carvacrol 21:599;28:406,426 acaricidal properties of 28:406 as bioactive monoterpenoid 28:426 (R)-Carvane 25:858 Carveol 25:145,147,149;29:83 activity in RAS assay system 29:83 activity in mam-2 assay system 29:83 cis and trans 25:148,150 (+)-trans-Carvol 21:417 R-(+)-p- Carvomenthene 8:49 from R-(+)-limonene 8:49 Carvomenthenol 28:426 as bioactive monoterpenoid 28:426 D-Carvone 10:43,46,47 R-(-)-Carvone 16:155 S-(+)-Carvone 16:155 (+)-Carvone 7:6,732,608;14:517;20:69, 70;21:585 ;27:364 (-)-Carvone 6:66,67,549-551,157,156, 623 ;14:517 ;21:417,585 ;27:364 Carvone 7:114,115;16:123;21:595,590, 622;23:342;25:145-149;27:378; 28:426;29:83 activity in AM assay system 29:83 activity in GST assay system
29:83 activity in RAS assay system 29:83 as bioactive monoterpenoid 28:426 of optical isomers 27:378 D-Carvone epoxide 10:43 Horner-Emmons reaction of 10:43 Lythgoe aldehyde from 10:46 C-Aryl glycoside 10:370 stereoselective synthesis of 10:370 C-Arylglycals 10:344 by palladium catalyzed coupling 10:344 synthesis of 10:344 Caryophyllan 26:601,604 Caryophyllene 18:607;23:535,548; 25:125,168 [3-Caryophyllene 21:585,607;26:409, 413;30:607,723 structure of 30:723 Caryophyllene oxide 20:660;21:616; 23:800;26:397,402;29:91 ;30:607 activity in CRG assay system 29:91 from Salvia sclarea 20:660 (-)-Caryophylle" e-4,5-oxide 25:168 [3-Caryophylleh,z-oxide 21:581,585,580 Caryophyllenol-I 23:800 Caryophyllenol-II 23:800 Caryophyllose 26:600,601 Caryophyllus flos 29:590 Caryopteris clandonensis 4:612 Caryoptoside 7:470 Caryose 26:603,604 Casalpinia sappan 24:275 Casbene 8:16,17,25,181 Casearia sylvestris 24:280-282 Casein kinase 25:545 Casein/CFA 30:775 CVE-treated mice 30:776 immunization with 30:775 Cashew phenols 9:314,332334,338,341,368,372 Casimiroa edulis 22:515 for convulsions in children 22:516
153 Casomorphin 27:803 Casopongia 25:695 Caspase activity 28:320 of TNF-c~ 28:320 Caspase inhibitor 25:2-VAD 25:462 Cassia occidentalis L. for 22:516 Cassia sophera L. for 22:516 Catunaregam nilotica as 22:516 Khaya ivorensis A. as 22:524 Khaya senegalensis as 22:524 Newbouldia leavis as 22:527 Phyllanthus urinaria L. as 22:529 Phyllostachys heterocycla as 22:529 Psidium guyava L. as 22:530 Spilanthes mauritiana as 22:532 Thuja orientalis L. as 22:534 Uncaria rhyncophylla as 22:534 Vernonia chinensis as 22:535 Vemonia hildebrandtii as 22:535 Vitex negundo as 22:535 Ximenia americana L. as 22:535 Caspase-3 26:913 Caspase-3 protease 25:469 Cassaine 21:89 Cassameridine 2:436 Cassane 25:241 Cassane skeleton 19:395 Cassia corymbosa 26:1140 Cassia fistula 29:617 Cassia garrettiana 22:626;28:574 Cassia leptophylla 20:486,487 Cassia occidentalis L. 22:516,580,582 for convulsions in children 22:516 Cassia siamea 1:174,385 Cassia singueana 22:580 Cassia sophera L. 22:516 Cassia sp. 29:420 Cassia torosa 22:580,581 Cassiadine 21:139 Cassigarol A 28:575 effects on tumor growth 28:575 Cassine 18:741
Cassine balae (Elaeodendron balae) 5:743,744,747;7:149,150 Cassine glauca 23:652
Cassine transvaalensis 23:653 Cassinia uncata 24:122 Cassinic acid 23:674 Cassipourea gerrardii 7:192 Cassipourea gummiflura 7:192 Cassipourine 7:192 Cassumins A, B, and C 17:365-367 Cassumunin B 23:845 (+)-Cassythicine 16:509 Castanea crenata 19:246 Castanea sativa 29:592 effects on cathepsin B, chymopapain,ficin and papain 29:592 effects on trypsin 29:592 from chestnut Fagaceae seed 29:592 Castanea sp. 29:585 (+)-6-epi-Castanosperime 12:276,342344 absolute configuration of 12:342 from Alexa leiopetala 12:342 from Castanospermum australa 12:342 from L-gulonolactone 12:342 synthesis of 12:342-344 (+)-Castanosperime 12:337,338 6-acetamido-6-deoxycastanospermine from 12:345 absolute configuration of 12:332 allergic enecphalomyelitis activity of 12:332 asymmetric synthesis of 12:346 castanospermine N-oxide 12:352 chemoenzymatic synthesis of 12:337,338 enzyme-catalyzed acylation of 12:346 fromAlexa leiopetala 12:332 from Castanospermum australa 12:332 inhibitory activity of 12:332 insect antifeedant activity of 12:332 O-acyl derivatives of 12:346 plant growth regulating activity of 12:332 relative configuration of 12:332 stereoselective synthesis of
154 12:353,354 synthesis of 12:321,332-342 X-Ray crystallography of 12:332 Castanospermine 10:553,656;11:267; 27:253 absolute configuration of 10:553, 656 activity against human immunodeficiency virus 27:257 almond emulsin [3-glucosidase inhibitor of 10:553 as an anti-inflammatory agent 27:257 as anti-aids agent 11:267 as anti-hyperglycemic agent 27:257 Baeyer-Villiger oxidation of 10:557,558 biological activities of 27:255, 256 by chiral allylic alcohol 11:267 enantiospecific total synthesis of 10:553 from Alexa leidpetala 10:553; 11:267 from Castanospermum australe 10:553;11:267 ~-glucosidase inhibition by 7:12 [3-glucosidases inhibition by 7:12 glucosidase I inhibitor of 10:527 glucosidase II inhibitor of 10:527 glucosidase inhibitor of 11:267 glucosidases I,II by 7:11-16 glycosidase inhibition by 27:256 lysosomal c~-and [3-glucosidases inhibitor of 10:553 maltase by 7:12 stereoselective 11:267 stereoselective synthesis of 10:557,558 sucrase by 7:12 synthesis of 1:279-281;10:531, 533;11:267-271 Wittig-Horner condensation of 10:557,558
(-)-6-epi-Castanospermine 12:342 from D-gluconolactone 12:342 Castanospermine 22:183,30 6-epi-Castanospermine 27:517 (-)-8-epi-Castanospermine 7:12-15 6-epi-Castanosperrmne 7:12-15 from Castanospermum australe 7:12 from D-galactose 12:344 from L-gulonolactone 7:12 synthesis of 7:12;12:342 ot-glucosidases inhibition by 7:12 epi-Castanospermine 7:44 Castanospermine inhibitor 27:525 of c~,[3,-glucosidases 27:525 Castanospermine N-oxide 12:352 from (+)-castanospermine 12:352 Castanospermine stereomers 12:342 Castanospermum austale 12:342,343; 24:917;27:255 australine from 10:567 (+)-6-epi-castanosperime from 12:342,343 Castasteron 18:495,503,522 Castasterone 16:324 from Castanea sp. 16:668 from cyclasterol 16:324 synthesis of 16:322 Castela texana 23:299 Castela tortuosa 23:296 Castelanone 11:80,81 from chaparrin 11:80,81 Casticin 7:226,411-413;26:803 Castilleja tenuiflora 24:799,835,836; 25:713 iridoids of 24:835,836 Castor fiber 5:221 Casuareinondiol 17:371 Casuarianjunghuhniana 17:371 Casuarianaceae 17:371 CAT 25:674 Catabolism 25:332,348 of haemoglobin 25:332,348 Catabolite repression 25:313 Catalase 9:578 Catalpa ovata 29:733 6,3'-epi-Catalpol 7:484
155
Catalysts 4:302 Catalytic asymmetric aldol reaction 18:485 Catalytic deuteriation 9:476 Catalytic domain 30:830 of plasminogen activator (u-PA) 30:830 Catalytic epoxidation 11:431,432 Catalytic hydrogenation 6:425;19:77; 24:179,180;30:454 ofarabino isomer 30:454 of racemic ketoacid 24:181,182 with raney nickel 6:425 with rhodium 6:424 Catalytic hydrogenolysis 12:163,293; 22:277 Catalytic osmylation 11:431,432 Catalytic receptors 18:694 Catalytic reduction 19:76,91 Catalyzed rearrangement 16:512 Catechin 2:232,233,752,192,144; 21:618;22:317,351,429,609,645,663; 23:749,752,772;25:541,612;26:743, 744,748,757 ;28:41,273 ;29:579,581 (+)-catechin 28:273 effects on ACE 29:579 effects on collagenase 29:581 (-)-epicatechin 28:273 epigallocatechin 28:273 epicatechin-gallate 28:273 epigallocatechin-gallate 28:273 (+)-Catechin 7:192;21:128,498,520, 521-523,525,526,528;23:745,747; 25:612;26:359;27:416,746,774,893; 29:572 effects on HIV- 1 protease 29:572 oxidation of 27:774 c~-Catechin 7:192,193 Catechin 3-gallate (flavan-3-ol) 29:584 effects on proteasome CHYlike activity 29:584 Catechin derivatives 25:612 (+)-Catechin oligomers 27:774 Catechin-3-gallate 26:359 Catechin-based flavones 25:541 Catechol 14:678;21:235;25:613,662, 929 Catechol borane reduction 13:562
Catechol monomethyl ethers 5:449,451 Catechol oxidase 25:654 Catecholamine O-methyltransferase 21:17 Catecholamine-induced vasoconstriction 30:55,56,72,76 Angelica keiskei use in 30:72 effect ofchalcones 30:56 in rat aortic rings 30:56 inhibition by Angelica keiskei 30:55 Catecholamines 22:18,24;25:516; 26:1019 dopamine 25:520 epinephrine 25:520 norepinephrine 25:520 Catecholates 9:537 Catecholborane 11:43,44;12:157,158 Catechol-containing inhibitors 30:226 Catecholic berberines 26:822 pessione 26:822 Catechol-O-methyltrans ferase 5:449; 21:50,57,84;22:665,9 Catechols 5:447,456,318,325,328, 578,579 Caterpillar data 24:866 bioassay of 24:866 Catha edulis 22:427,436;23:652,660 Cathansterone 23 a-hydroxylation 25:421 Catharanthine 2:370373,381,383,385, 390,392,398,39,400,401,402 ;4: 31, 32; 13:663;14:809,810,820,821, 854-859,869-873 ;26:139;27:747,782 15',20'-anhydrovinblastine from 14:820,821,869-873 biosynthesis of 4:66 biosynthetic precursor of 4:31 catalytic hydrogenation of 14:809,810 coupling with vindoline 4:31,32 dihydrocatharanthine from 14:809,810 enzyme catalyzed coupling of 14:820,821 from Catharanthus roseus 13:663 from catharanthus roseus 14:855
156
vinblastine from 14:854-859 vincristine from 14:854-859 with vindoline 14:820,821 Catharanthine N-oxide 2:371,816,187; 3:857,859 (16 'S)-anhydrovinblastine from 14:857,859,816,817 Catharanthus roseus 19:246;22:9; 24:774 ;25:384 ;26:144 ;26:217,828, 829,753 ;27:744,780,782 alkaloid production of 2:370-391 alkaloids of 7:416 catharanthine from 13:663; 14:855 growth inhibitory activity of 7:416 leurosine from 14:860 vinblastine from 8:283;14:805 vincristine from 8:283;14:805 vindoline from 14:805;22:9 Catharine 2:370372,387,390-398 biosynthesis of 14:820,821 from anhydrovinblastine 14:812, 820,821,871 from leurosine 14:812 Catharinine 1:90,91 biosynthesis of 14:820,821 from anhydrovinblastine 14:820, 821,871 from 20'-deoxyleurosidine 14:812 synthesis of 14:847 Cathasterone 25:415,420 Cathedulin K 23:675 (+)-Cathenamine 13:490,491 Cathespin 26:913 Catheters 22:56 Cathinone 21:57,84;22:14 (-)-Cathinone 22:24;23:660 Cation channel 22:25 Cationic cyclization 14:793-795 (+)-chelamine by 14:793-795 (+)-chelidonine by 14:793-795 sanguinarine by 14:793-795 Cationic cyclopentannelation reactions 14:583-630 Cationic polyene polymerization 1:565
Cationic n-cyclization 12:287 of N-acyliminium ion 12:287 Cativic acid 25:254 Catunaregam nilotica 21:660;22:516 for convulsions 22:516 for convulsions in childrens 22:516 Caudatoside 26:719,720 Caudicifolin 9:288 X-ray crystal analysis of 9:288 Caudinoside A 7:278 from Parachaudina ransonetii 7:278 Caulerpa racemosa 18:689,714 Caulerpalean algae 18:688 Caulocyctis cephalornithos 15:386 Caulophyllum thalictroides 27:277 Cavernothiocyanate 25:858;28:662 spectral data of 28:662 (+)-Cavinton 18:331 Cavinton 19:89 Cayaponia tayuya 24:249 CBI cannabinoid receptor 30:196,198 affinity for 30:196 3-alkyl-5-arylimidazolidinediones as 30:198 CBz receptor 25:532,533;30:196 cannabinoid affinity for 30:196 N-Cbz-(S)-leucinal 12:489 Cbz-L-alanine 16:9 C-C bond formation 6:307-349 CC-1065 3:310,302,305 absolute stereochemistry 3:305 antitumor activity of 3:310,302 CDPI dimer 3:331,356-360 DNA sequence selectivity 3:304 formal synthesis of 1:180,184 isolation of 3:301 mechanism of action 3:303,304 molecular mechanic simulation 3:338-351 structure of 3:301 structure-activity relationship 3:338-351 synthesis of 3:331,356-460 synthesis of analogs 3:352 synthetic studies towards 3:301-383 total synthesis of 3:333-337
157 toxicology of 3:302 X-ray crystal structure 3:305 CC57BC-1 24:956,957 bioactive compounds from 24:956,957 CCK hormone 18:834 CCK-10,-12,-13 18:838 CCK-4,-5,-8,-18,-25,-33,-39, and -58 18:825 CCK-A antagonist 18:863 CCK-analog [Thr,Nle]-CCK-9 18:836 CCK-B antagonist 18:863 CCK-peptides 18:825,827,836,852,854, 857,859,860 CCK-radioligand 18:861 CC14-induced cytotoxicity 25:468 CC14-induced liver injury 25:466,469 CC14-induced liver injury model 25:471 CD correlation 6:137 of 19'-hexanoylfucoxanthin 6:137 of peridinin 6:137 with grasshopper ketones 6:137 CD Cotton effects 17:44 CD data 23:433 of agrimoniin 23:433 of casuarictin 23:433 of corilagin 23:433 of geraniin 23:433 ofnobotanin F 23:433 ofoenothein B 23:433 ofpedunculagin 23:433 ofrugosin D 23:433 of tellimagrandin I 23:433 oftellimagrandin II 23:433 CD excition chirality method 17:35,36, 51,53 CD procedure 9:27 absolute stereochemistry by 9:27 CD spectral analysis 6:539 of (+)-epiperiplanol-B benzoate 6:539 CD20 antigen 25:272 CD25 positive cells 25:454 CD4 positive cells 25:454 CD4 receptor 30:398 interaction of 30:398 CD4 T-lymphocytes 30:396
CD4-antigens 25:454 CD4-positive helper T cells 25:450 CD69 positive cells 25:454 CD71 positive cells 25:454 CD8 positive cytotoxic T lymphocytes 25:454 Cd-induced liver injury model 25:471 CDK2 activity 21:638 CDK2 tyrosine phosphorylation 21:136 CD18 antigens 25:454 cDNA clone encoding tomatinase 25:308 cDNA coding 25:61 cDNA copy of the HIV type-1 (H1V-1) genome 25:941 CDPK 25:542,546 inhibitors of 25:544 CD-spectroscopy 23:431 of ellagitannin oligomers 23:431 Ce (OAc)3-BFaOEt2 10:572 Ce (OAc)3-BF3OEt2 10:572 Cebocephaly 7:21;23:570 Cecropia juvenile hormone 3:271 synthesis of 3:271 Cecropia moths 22:82 squalamine from 22:82 Cecropin-B 27:806,807 Cecropins 22:83 Cedecea lapagei 28:404 Cedranolides 5:778-792 5-Cedranone 5:791-792 8,14-Cedranoxide 8:163-165 retrosynthesis of 8:163 synthesis of 8:163,164 total synthesis of 8:163-165 Cedrela tubiflora Bertoni 30:401 antiviral activity of 30:401 c~-Cedrene 15:270,609 A2-Cedrene 19:136 Cedrene 28:406 acaricidal property of 28:406 2-epi-~-Cedrene isoprenologue 15:270 Cedrene isoprenologues 15:269-271 13-Cedrene- 14-ol 8:164,165 Cedrol 5:782,788,790 Cedronia granatensis 23:301 Cedrus deodara 8:415;28:402,416
158
Cedrus odollam 22:516 for epilepsy 22:516 Cefotaxime 26:333 Cefoxitin 6:322 Cefriaxon 25:258 Ceftazidine 25:258 Ceiba pentandra 29:708 Celangulin 18:771;23:667 from Celastrus angulatus 18:771 Celangulin (II) 23:667 Celangulin (III) 667 Celangulin (IV) 23:667 Celapanol 18:744 Celaphanol A 29:91 activity in NFkB assay system 29:91 activity in NO assay system 29:91 Celasdin-B 30:643 NOESY of 30:643 HMBC of 30:643 structure of 30:644 Celasdine A 23:702 Celasdine B 23:702 Celasdine C 23:703 Celastolide 30:640 ~3C NMR spectra of 30:640 ~H spectra of 30:640 IR spectra of 30:640 structure of 30:640 Celastraceae 26:813 Celastraceae family 30:636,642,695 antifeedant activity of 30:695 genera of 30:636 insecticidal activity of 30:695 species of 30:636 triterpenes from 30:642 Celastroids 23:708 basic nucleus of 23:708 Celastrol 5:744-746,757,776;30:664 Celastrolides 30:642,693 against multidrug-resistant strain 30:694 against drug-sensitive strain N 30:694 from celastraceae family 30:642 Celastroloids 23:662 Celastrus angulatus 18:771;23:654,666 antifeedant activity of 23:666
insecticidal activity of 23:666 of spinach phenols 23:765 of tomato peel phenolics 23:766 Celastrus flagellaris 23:667 Celastrus gaumeri 30:691 in treatment of diarrhea 30:691 in treatment of snake bite 30:691 Celastrus gemmatus 23:667 Celastrus glaucophyllus 23:654 Celastrus hindsii 30:690 celasdin A from 30:690 celasdin B from 30:690 celasdin C from 30:690 maytenfolone-A from 30:690 Celastrus orbiculatus 29:88,91,708 Celastrus paniculata 5:743,744,747; 20:521 ;21:614;22:516;23:654 as antiepileptic 22:516 Celastrus pomonella 30:697 mortality of 30:697 Celastrus rosthornianus 23:667 Celastrus scandens 23:655;30:664 celastrol from 30:664 pristimerin from 30:664 Celastrus sp. 18:741,753;23:651 Celastrus stephanotifolius 23:672; 30:646 lupane caffeoyl esters from 30:646 Celecoxib 30:192 as COX-2 inhibitor 30:192 Celenamide 25:757 Celenamide E 25:778 Celery furocoumarins 744 Celestraceae 7:150 Celestrol 7:146,147,150-152 Cell adhesion 24:1085 inhibitors of 24:1085 Cell aggregation factors 24:1062 Cell apoptosis 26:925-926 role of nitric oxide in 26:925-926 Cell cultures 7:94-96 organogenesis of 7:94-96 totipotency of 7:94-96 Cell differenciation 26:926 role of nitric oxide in 26:926 Cell division protein kinases (CDKs) 25:526
159
Cell growth inhibitory agent 30:5 (+)-discodermolide as 30:5 Cell membrane stabilisation 30:523 due to Cs0-carotenoids 30:523 Cell proliferation 30:5,367,495 assessment of 30:495 in vivo inhibition of 30:5 inhibition by 16-desmethyl 30:5 inhibition by (x-thioanomers 30:5 inhibition by [3-thioanomers 30:5 inhibitor of 30:5 role of serotonin (5-HT) 30:367 Cell surface glycoprotein 26:950 Cellaria pilosa 17:95,101 Cellaria sp. 17:89,92 Cell-cell communication 30:523 Cell-free assays 29:40 abutasterone activity in 29:42 ajugalactone activity in 29:42 ajugasterone C activity in 29:42 as gel-shift assays 29:40 as radioligand displacement assays 29:40 cyasterone activity in 29:42 5-deoxykaladasterone activity in 29:42 ecdysone activity in 29:42 22-epi-ecdysone activity in 29:42 24- flur o- 20- hydroxyecdys one activity in 29:42 20-hydroxyecdysone activity in 29:42 inokosterone activity in 29:42 makisterone A activity in 29:42 polypodine B activity in 29:42 ponasterone A activity in 29:42 poststerone activity in 29:42 turkesterone activity in 29:42 Cell-mediated immunity 30:766,768, 773 against Listeria 30:768 macrophage activation in 30:773 role of cytotoxic T lymphocyte (CTL) 30:773 Cellobiohydrolases II 8:351 from Trichoderma reesei 8:351 Cellobiose analogues 7:64-66
c~-Cellobiose from 7:58 [3-Cellobioside 7:52 Cellobioside hydrolase II 7:58 [3-cellobiose from 7:58 [3-Cellobiosyl fluoride 7:58 Cello-oligosaccharides 7:33 Cellular activity 23:168,180 of secosterols 23:168,180 Cellular toxicity 27:876 ofokadaic acid 27:876 2-Cellulases 7:3,37,39,59,349,340, 344,352 Cellulasic 24:983-998 enzymatic activity 24:995-998 Cellulomonas dehydrogenans 7:69 decapenoxanthin from 7:69 Cellulose 5:32,275,276,268,14:268; 23:109 m-Cellulose 7:195 Cellulose 1,4-[3-cellobiosidase 7:3 DEAE-Cellulose chromatography 2:392,393,394 Celmer's model 23:86 Celorbicol 18:743 Celosai argentea 25:476 Celosian 25:476 Celtis cinnamomea 22:516 for convulsions 22:516 Celux pipens 19:481 ~-Cembra-2,7,11-triene-4,6-diol 29:100 activity in EBV assay system 29:100 activity in PKC assay system 29:100 activity in skin-1 assay system 29:100 activity in ODC assay system 29:100 [3-Cembra-2,7,11-triene-4,6-diol 29:100 activity in EBV assay system 29:100 activity in skin-1 assay system 29:100 activity in ODC assay system 29:100 Cembradiene hydroxy ether 15:253 Cembranes 15:253,22,28;23:172 Cembrane precursor 23:175
160
Cembranoid diterpenes 21:277 Cembranoids 8:15 anticancer activity of 8:15 Cembranolide 24:439 as FPTase inhibitor 24:439 as rHFPtase inhibitor 24:440 structures of 24:439 (7E)-Cembranolides 10:16 cis-Cembratriene 15:275 Cembratriene-4,6-diols (c~,[3-CBT) 3:4 cx,[3-CBT (Cembratriene-4,6-diols) 10:3,4 Cembrene 8:16,25 Cembrene A 5:701,702,220,221,255; 8:220;12:181 (-)Cembrene-A 5:701,702 3Z-Cembrene-A 8:221 Cembrenoids 23:176 Cembrolides 23:175 Cenarchaeum symbiosum 25:718 Cendranes 29:87 Centaur X3 7:202,203,221 Centaurea 29:580 Centaurea cyanus 22:679 Centaureidin 7:226;22:481;30:727,728 identification of 30:727 isolation of 30:727 structure of 30:728 Centella asiatica L. 21:674;22:516 asiaticoside from 21:674 Centipeda minima 26:808 Centipeda orbicularis 22:516 for epilepsy 22:516 Centraherin 29:89 activity in NFkB assay system 29:89 Central analgesic activity 30:200 in anilidopiperidines 30:200 Central nervous system 21:581 ;28:315; 30:194,370,384,799 cannabinoid receptors in 30:194 depressent activity on 21:581 effect of Crocus sativus 28:315 on central nervous system 21:581 opioid system in 30:799 parts of 30:370 TPH activity in 30:370
Central opioid receptors 30:816 intrinsic activity of 30:816 Centrifugal Liquid Chromatography (CLC) 24:137 Centrifugal partition chromatography (CPC) 25:207 Centrocerus clavulatum 26:478 (3R,7S)-Centrolobin 17:366 (3R,7R)-Centrolobin 17:367 Centrolobium paraense 17:367 Centrolobium robustum 17:367 Centrolobium sclerophyllum 17:367; 26:902 Centrolobium sp. 17:358,366 Centrolobium tomentosum 17:367 (-)-Centrolobol 17:358,361 (-)-(R)-Centrolobol 17:361 Centrolobol 17:367 Cephaelis ipecacuanha 21:97;26:144, 836 emetine from 21:97 Cephalodiscus gilchristi 18:875,876, 901,902 Cephalomannine 11:4,5,61 ;12:179,180; 20:81;25:245 Cephalosporin-C 11:211,212;22:247 biosynthesis of 11:211,212 from 5-(L-ot-aminoadipoyl)-Lcysteinyl-D-valine (LLD-ACV) 11:211,212 from penicillins 11:211,212 Cephalosporin P1 21:237 Cephalosporium acremonium 11:211, 619;22:263 Cephalosporium aphidicola 21:721; 24:197;25:153,155 aphidicolin from 22:234 Cephalosporium caerulens 5:613 Cephalotaxaceae 26:185 (+)-Cephalotaxine 18:319;19:141 Cephalotaxus alkaloids 24:294 cytotoxicity of 24:294 Cephalotaxus harrington var. drupacea 24:289,291 Cephalotaxus sp. 3:455,483,484;19:141 Cephalothin 6:322 Cephalothrix linearis 18:725 Cepharadione A and B 20:481 ;25:197 Cepharanthine 21:80
161
Cephotaxime 30:693 Ceramide 1-sulfates 28:621 as DNA topoisomerase I inhibitor 28:621 Cerastoma brevicaudatum 28:651 (methylthio) furodysinin from 28:651 dithiofurodysinin disulfide from 28:651 Ceratinamides A and B 25:620,784 Ceratiomyxa fruticulosa 29:237 Ceratitis capitata 5:223 2,5-dimethyl-3-ethyl-pyrazines of 5:223 Ceratocistis fimbriata 5:305,306,351; 23:355;25:485 Ceratocystis 25:129 Ceratocystis brunnea 5:306 Ceratocystis minor 15:385 Ceratocystis paradoxa 5:306,307 Ceratocystis sp. 5:296,305,309,325; 26:1127 Ceratocystis stenocerus 5:305 Ceratocystis ulmi 5:305 Ceratodictyon spongiosum 25:902; 28:683 cis, cis-ceratospongamide of 28:683
trans, trans-ceratospongamide of 28:683 Ceratonia siliqua 21:504;26:1139,1142 Ceratosoma brevicaudatum 25:815 Ceratozamia spinosa 26:1158 C-erbB-2-kinase 25:797,799,870,871 Cerbera mangmas 7:176 Cerbera odollum 7:195;22:516 Cerberalignan A 20:273 Cerbinal 16:302-304 antifungal activity of 16:302-304 from Cerbera manghas L. 16:302 synthesis of 16:302-304 Cercidothrix Bunge 27:444 Cercis siliquastrum 26:1145 Cercospora beticola 15:351;22:459 Cercospora taiwanensis 15:383 Cereale secale 9:328 Cerebellar dysfunciton 26:1130 as syndrome type-lA 26:1130
Cerebellar granule cells 25:268 role in apoptosis 25:268 Cerebellar white matter 30:375 hyperplasia of 30:375 Cerebral cortex 30:193,370,377 serotonergic innervations in 30:377 Cerebral grey matter 30:375 hyperplasia of 30:375 Cerebral thrombus 30:839 fibrinolytic agent in 30:839
Cerebrotendinous xanthomatosis 17:207 Cerebrum rudimentary 23:566 Ceric ammonium nitrate 4:322,323, 331,332;25:821 Ceric chloride 1:552 Ceridimine 5:123 Ceriops decentra 7:192 Ceriops sp. 7:176 Ceriops tagal 7:176,180,195 Cerium (III) chloride 14:753 Cerium ammonium nitrate (CAN) 14:780 Cerium carbanion 1:552 Cemilton 27:212 in treatment of benign prostatic hyperplasia 27:212 Ceroplasteric acid 1:563-564 (+)-Ceroplastol I 18:20-22 Cerotoma trifurcata 9:392 Cerulenin 5:600,609,613-615 Ceruloplasmin 22:9,327;26:1012,1016 Cervical carcinoma 25:268;30:405 Cesium fluoride 1:563,564 Cestode (tapeworm) 12:7 Ceterach officinarum 29:573,580 Cetraria islandica 5:309,310,322 Cetraria richardsonii 5:310,311 N-Cetyl-cysteine 26:993 Ceveratrum group 23:563 Ceylanicine 5:146,147 Ceylanine 5:147-149 (~-C-Glycosides 10:381 by condensation of methylallyl tri-n-butylstannane 10:381 by condensation with furan 10:377 by reaction of acylester 10:371
162
from pyridyl thioglycoside 10:382 from et-tri-n-butyltin glycoside 10:384 stereoselectivity of 10:371 with allyltrimethylsilane 10:371 [3-D-C-Glycosides 10:383,384 from 3,4,6-tri-O-t-butyldimethylsilyl-2-deoxy D-glucopy ranosyl phenylsulfone 10:383, 384 C-Glycosyl compounds 10:373,374 by catalytic siloxymethylation of O-acylglycosides 10:373,374 by reaction with HSi R3/CO/ Co2(CO)s 10:373,374 C-Glycosylarenes 10:380 by reaction of benzoylated Oalkyl glycosides 10:380 C-Glycosylation 10:387 of aromatic ring 10:387 ofheterocyclic ring 10:387 C-Glycosylcyanides 10:355 from acylated bromosugars 10:355 synthesis of 10:355 C-Glycosyl-oxirans 10:361 from acetobromoglucose 10:361 cGMP PDEs 25:523 cGMP-gated ion channel 25:541 cGMP-gated Na+channels 25:517,521 cGMPphosphodiesterase 25:521 cGMP-radioimmunoassay 26:938 CGP-41251 12:388 cyclic AMP-dependent protein kinase inbitor 12:388 $6 kinase inhibitor of 12:388 tyrosine specific protein kinase inhibitor of 12:388 CH3SOCH2 27:512 from dimethylsulphoxide 27:512 a-Chaconinase 25:305 Chaconine 23:575,584 c~-Chaconine 7:190-192,194,195;21:80; 25:300,305,311 ;26.'467,817, 868 Chactomellic acids 24:418-428 2D structure alignment of 24:421 FPP mimetics 24:420
structure-activity relationship of 24:426-428 structures of 24:419 synthesis of 24:421-426 Chaenorhabdtis 26:429 Chaetoglobocins 4:620 Chaetoglobosin D 13:108 Chaetoglobosins 13:108,150,355 Chaetomella acutiseta 21:194 chaetomellic acid A from 21:194 chaetomellic acid B from 21:194 Chaetomellic acid A 21:194 Chaetomin 21:220,240 Chaetomium 5:730,203 Chaetomium cochiliodes 25:168,170 Chaetomium globosum 21:211,220, 221,229;28:125 2-(buta- 1,3-dienyl)-3-hydroxy4(penta- 1,3-dienyl) tetrahydrofurane from 21:211 Chaetomium sp. 21:220,221;27:382 Chagas disease 2:293,302;24:818,819; 26:673,787 ;30:740 by Trypanosoma cruzi 30:740 treatment of 26:787 Chain elongation 4:199 of D-mannopyranose system 4:199 Chaksine 21:139 Chalcomoracin 17:465;28:210 biosynthesis of 17:465 from moraceous plants 28:210 Chalcones 7:427;13:450-452;22:432, 345,420;23:841 ;26:800;27:745,928 antiparasitic activity with 26:800 molluscicidal activity of 7:427 E-Chalcone 26:471 Chalcone derivatives 7:207 in Artemisia palustris 7:207 Chalcone isomerase 25:668 Chalcone reductase 25:653 Chalcone synthase 25:655 malonyl-CoA 25:655 Chalcone synthesis 21:742 Khan's method for 21:742 Chalcone-synthase 25:504 Chalogens 9:109-126 Chamaecaparis nootkatensis 23:341; 28:408
163
Chamaecyparis obtusa 25:246;28:234 Chamaecyparis pisifera Endle 24:206; 29:170 Chamaecyparis sp. 21:615 Chamaesaracha conioides 22:28 Chamberlin 12:445 Chamic acid 23:341,345 (+)-[3-Chamigradiene 6:63 Chamigrane 9:344,59 Chamigrane-type derivative 25:701 Chamigrane-type, halogenated 25:702 Chamigrenal 26:244 as PAF-induced inhibitor 26:244 Chamigrene precursor 6:30 Chaminic acid 23:341,345 Chamomila recutita 22:427 fl-D-glycosyl-7-apigenine from 22:427 luteolin from 22:427 quercetin from 22:427 Chamydosporol 13:543[3toxicity of 13:543 Chan-Brownbridge procedure in (-)-pseudopterosin-A synthesis 6:74,75 Chanoclavine I 11:199,200 Chaparrin 7:381,394,80,81 Chaparrinone 5:38-41,380-381,392, 395-396;23:301 ;26:816,817 Chara globularis 18:677 charamin from 18:677 3-azelidinol from 18:677 4-azoniaspiro [3,3] heptane-2,6diol from 18:677 Charamin 18:677 from Chara globularis 18:677 Charania lampas 15:58,88 Charatoxins 18:697 Charged carotenoid species 30:515 Charonia sauliae 7:306,724 Chartella papyracea 17:85,86,89,92, 692 Chartellamide A & B 17:86 Chartelline A,B & C 17:86 Chaulmoogric acid 8:140 Cheilantes 26:722 Cheimonophyllal 26:457 Cheimonophyllon A&D 26:457
Cheimonophylum candidissimus 26:456,457 (+)-Chelamidine 14:796 from berberine 14:796 synthesis of 14:796 (+)-Chelamine 14:793-795 from coptisine 14:793-795 stereochemistry of 14:793,794 synthesis of 14:793-795 through cationic cyclization 14:793-795 Chelaner antarcticus 6:436,445 pyrrolidine venom alkaloids in 6:436 pyrrolizidine alkaloids in 6:445 Chelate model 11:268,269 Chelating transition state models 12:167 c~-Chelation 11:234 ~-Chelation 11:234 Chelation 12:149,150 Chelation controlled 10:286 Chelation controlled aldol condensation 10:286 Chelation controlled Grignard reaction 1:266 Chelation directed addition 3:271 Chelation-controlled addition 14:50 Chelation-controlled alkylation reaction 30:12 Chelation-controlled reduction 30:11 Chelation-controlled Sakurai reaction 12:333 Chelelactam 27:167 Chelerythrine 14:773-775,796;21:69; 22:26,77 ;26:488;27:158,163,164, 172,863 biological activities of 27:178, 179 from berberine 14:773-775,796 from oxychelerythrine 14:774, 775 synthesis of 14:773-775,796 through enamide-aldehyde cyclization 14:774,775 Chelflutine 22:77 Chelidonieae 27:161 (+)-Chelidonine 14:793-795 biosynthesis of 14:770,771
164 from coptisine 14:793-795 synthesis of 14:793-795 through cationic cyclization 14:793-795 Chelidonine 21:96 Chelidonium majus 27:155,158,159, 162,168,169;29:592 Chelidonium majus L. 27:158 Cheliferoside 15:59 from Lathasterias nanimensis chelifera 15:59 Chelilutine 14:780,781;27:156-166,172 10-hydroxychelerythrine 27:156, 157 10-hydroxysanguinarine 27:156, 157 12-hydroxychelirubine 27:156, 157 biological activities of 27:178, 179 biological activities of 27:178, 179 chemical reactivity of 27:166 from 7-O-demethyl dihydro chelerythrine 14:780,781 isolation of 27:164-166 synthesis of 14:780,781 Chelirubine 14:777,778 biosynthesis of 14:779 from protoberberines 14:777,778 from sanguinarine 14:779 synthesis of 14:777,778 Chelynotus semperi 17:23;21:269; 25:893;28:639 Chemic acid 23:345 Chemical carcinogenesis studies 30:592 in epidermal cell culture 30:592 of BALB/c mice 30:592 Chemical classification 20:136-139 of withanolides 20:136-139 Chemical correlation 26:117 of strictosidine and vincoside 26:117 Chemical defence compounds 21:108 Chemical degradation 23:30; 27:191-196 of benzoxazinoid acetal glucosides 27:191-194 of low density lipoprotein
27:846 ofSAMM 2 23:30 Chemical ionisation (C.I.) 9:466,470, 477 Chemical manganese dioxide (CMD) 4:85 Chemical methods 26:552 of structural analysis 26:552 Chemical properties 27:336,507 of cyclopropane 27:336 ofpolysaccahride F-8 27:507 Chemical reactivity 27:156-166 of chelilutine 27:156-166 Chemical reactivity screening 29:647 colorization reactions of natural products in 29:647 high-performance thin-layer chromotography (HPTLC) in 29:647 Chemical synapses 21:8,9 Chemical synthesis 27:196,207-210 of benzoxazinoid acetal glucosides 27:191-194 of benzoxazione aglucones 27:190-191,195,196-207 Chemical transformation 26:101,102 of bakankosine 26:101,102 of secologanin 26:97,99 of sweroside 26:103,104 Chemical transformation methods 30:591 in vivo 30:591 role in chemopreventive activity 30:591 Chemical-induced edema 12:398 Chemical-induced neoplasia 30:311 solid tumor (sarcoma-180) as 30:311 Ehrlich ascites model as 30:311 juglone against 30:311 plumbagin against 30:311 Chemiluminescence 25:940 Chemoconvulsants 22:508 Chemo-differentiation therapy 30:498 of acute monocytic leukemia 30:498 Chemokines 25:535 Chemo-perception system of plant cell 25:394
165
Chemopreventive activity 30:591,597, 766 in mouse mammary organ culture model 30:591 in vitro 30:597 in vitro bioassays for 30:591 of Chlorella vulgaris 30:766 of isoquinoline alkaloids 30:597 of lignans 30:597 Chemopreventive agent 26:219 genkwanin as 26:219 (+)-lariciresinol as 26:219 sitoindoside II as 26:219 Chemopreventive efficacy 27:386 of limonene carcinogenesis 27:386 Chemoprophylaxis 26:674 Chemoselective epoxidation 14:366 Chemoselective hydroxylation 6:79 ofbicyclic triene 6:79 Chemoselective reduction 10:85;30:25 of unsaturated ester 30:25 with lithium tri -tertbutoxyaluminohydride 10:85 Chemosensitizers 30:595 antimalarial drugs as 30:595 Chemosy stematics 6:133-135 of acetylenic carotenoids 6:147 ofallenic carotenoids 6:133-135 Chemosystematic markers 6:155 acetylenic carotenoids 6:155 Chemotactic tripeptide 25:275 Chemotaxonomic markers 26:1128 Chemotaxonomy 27:369 Chemotherapeutic agent 30:5,330,742 atovaquone 30:330 for colon cancer 30:5 for multi-drug resistant cancers 30:5 for taxol-resistant breast cancer 30:5 Chemotherapeutic intervention 30:397 targets for 30:397 Chemotherapy 26:781,782,783 of malaria 26:781,782,783 Chemotherapy drug 27:436 antitumor activity of 27:436 Chenodeoxycholic acid 17:207 Chenopodium album 7:398
Chenopodium ambrosioides 20:12; 26:431
Chenopodium Chenopodium Chenopodium Chenopodium
anthelminticum 20:12 botrys 21:584 quinoe 9:402
spp. 28:392 Cherimolin 26:441,442 Chest pain 30:203 use of ginseng root in 30:203 Chewed garlic 23:465 Chichipegenin 27:44,45 structure of 27:45 Chida's synthesis 30:38-40 of (-)-pironetin 30:38-40 Childhood disintegrative disorder (CDD) 30:384,372 Chiliophyllin 27:559 Chilo suppressalis 24:715 ;29:25,29 ajugasterone B activity in 29:28 makisterone D activity in 29:28 shidasterone (stachysterone D) activity in 29:28 213,3{3,20R,22R,25-pentahydroxy14[3-methyl-5 [3-cholest-7,12dien-6-one activity in 29:28 Chilomonas paramecium 2:294 Chiloscyph-2,7,9-trione 20:473 Chiloscyph-2,7-dione 20:473 (+)-Chiloscypholone 18:624 Chiloscyphone 18:609;20:473 from Chiloscyphus polyanthos 18:609 Chiloscyphus polyanthos 2:278,279; 18:609 Chiloscyphus rivularis 20:472 Chimanine B&D 26:820,821 Chimeramycin 5:613,614 Chimeramycins A&B 5:614 Chinensinaphthol methyl ether 26:194 Chinese crude drug 28:202 sanggenon A from 28:202 sanggenon C from 28:202 sang-Bai-Pi as 28:202 Chinese medicinal plants 21:729 bioactive natural products from 21:729 Chinese mulberry tree 28:202 isoprenylated flavonoids from 28:202
166
Chippiine 5:128 Chiral 1,3-dioxane 14:480 Chiral 1,4-dihydropyridine 14:744 isonitramine from 14:744 Chiral 1-acylpyridinium salt 12:351 Chiral 2-amino alcohol 12:415,416 synthesis of 12:415,416 Chiral 4-hydroxyoxazolidin-2-ones 12:450 Chiral acetals 14:506,507 asymmetric cyclization of 14:506,507 asymmetric synthesis from 14:496-516 bromination of 14:505,506 diastereoselective 14:505,506 for asymmetric bromolactonizations 4:338,339 from (-)-(2S,3S)- 1,4-dimethoxy2,3-butanediol 14:496 from (2R,4R)-pentanediol 14:473 from (2S,4S)-pentanediol 14:481 from 1,3-diphenylpropane- 1,3diol 14:480 from C2-symmetric diols 14:469-516 from dialkyl tartarate 14:505,506 from perillene 14:506,507 nucleophilic additions of 4:330-332 preparation of 4:324 with methallylsilane 14:481 with trimethylsilyl cyanide 14:473 Chiral acetylenic acetals 14:471 chiral alkoxy-allenes from 14:471 with Grignard reagent 14:480 Chiral acrylates 8:416 Chiral acyclic ~-keto acetals 14:501 from (-)-(2R, 3R)-2,3-butanediol 14:501 LiA1H4-reduction of 14:501 Chiral alcohols 14:470 Chiral alkoxy-allenes 14:480 from chiral acetylenic acetals 14:480 synthesis of 14:480
Chiral alkyl (1,3-butadien-2-yl) methanols 14:474 Chiral allylboronates 11:423,424 synthesis of 11:423,424 Chiral allylic alcohols 4:160-161 Chiral amide bases 10:31-33 [2,3] Wittig ring contraction with 10:31-33 Chiral amines 14:496 from chiral imine 14:496 Chiral aryl Grignard reagents 14:508, 509 diastereoselective addition of 14:508,509 Chiral arylaldehyde acetal chromium tricarbonyl complexes 14:511 asymmetric metallation of 14:511 Chiral auxiliaries 4:327 acetals as 4:327 asymmetric induction with 4:327-345 binaphthyl diols as 4:335 by (R)-(+)-cx-methyl benzylamine 4:324 by 1-(-)-methyl ester 4:323 chiral diamides as 4:335 glycosides as 4:327 in asymmetric Diels-Alder reaction 4:345 in Diels-Alder reactions 4:334-336 oxazolines as 4:327,332,333 preparation of 12:416-418 prolines as 4:327 stereo-differentiating reactions 4:327 sugar as 4:334-336 thiazolidine derived 14:735 Chiral boron reagent 4:609 from B(OCH3)-(R,R)-(+) tartaric acid 4:609 in asymmetric Diels-Alder 4:609 Chiral building blocks 13:73-84;29:419 asymmetric synthesis of 14:551-581 from malonic acid derivatives 13:73-84 in synthesis of 3-piperidinol
167 alkaloids 29:419 6-membered lactam as 29:419 monofluorinated 13:81 preparation of 4:349-359,73-84 stereodivergent process for 29:419 via intramolecular Michael reaction 14:551-567 Chiral carbapenems 12:121 Chiral catalysts 17:479 Chiral chromatography 18:411 Chiral cyclized hemiacetal 14:487 from chiral vinyl ether 14:487 Chiral cycloalkanone acetal 14:486 chiral vinyl ether alcohols from 14:486 from (-)-(2R,4R)-2,4-pentane diol 14:486 Chiral cyclopropanation 14:401-405 of chiral pyrethroid analogues 14:401-405 of thujone 14:401-405 Chiral dienophiles 8:140 cycloaddition of 14:503 ct-hydroxcarboxylic acid derivatives 8:140 isoquinolinium salt with 14:503 Chiral dienyl ether alcohol 14:487,488 (+)-africanol from 14:487,488 cyclopropanation of 14:487,488 Chiral dioxane acetals 14:476 asymmetric nucleophilic cleavage of 14:476 diastereoselective cross-aldol reaction 14:472 from (2S,4S)-2,4-pentanediol 14:471 from (2R,4R)-pentanediol 14:477,478 with organometallic reagents 14:476 with Reformatsky reagents 14:477,478 Chiral enamine 14:553 asymmetric 14:553 intramolecular Michael reaction of 14:553
Chiral enol ethers 14:489 asymmetric 14:489 C-N bond formation 14:489 Chiral enone acetal 14:510 Chiral epoxidizing agent 4:172,173 diastereofacial selectivity of 4:172,173 chiral lactones 4:493 from c~,[3-acetylenic alcohols 4:493 from keto acids 4:493 preparation of 4:493 Chiral ester 14:552 Chiral fragments 6:282 ofamphotericine B 6:282 synthesis of 6:282 Chiral imine 12:161 [2+2] cycloaddition of 12:161 from ethyl (S)-lactate 12:161 addition of organometallic reagents 14:496 chiral amine from 14:496 Chiral imine acetal 14:497,498 with lithium enolate 14:497,498 Chiral inducer 1:73 Chiral induction 18:480 with Schoellkopfreagent 10:653, 655 Chiral isoquinolines 10:671 synthesis of 10:671 Chiral Lewis acids 8:140 Chiral molecules 21:580 Chiral monoterpenes 27:372 3-carene 27:372 Chiral monoterpenoids 27:361,381 antibacterial activity of 27:381 antifungal activity of 27:381 anti-neoplasmatic activity of 27:386 bioactivity of 27:361,377 isomerism of 27:361 Chiral N-acylated 2-oxazolone 12:419 2-amino alcohol synthon from 12:419 electrophilic addition of 12:419 from camphor-derived carboxylic acid 12:419 with bromine and phenyl selenyl
168
chloride 12:419 with DPPO• 12:419 Chiral N-glycosyl nitrones 1:370,371 Chiral nitroolefination 14:631-644 ofenolates 14:631-644 Chiral ortho ester 14:508 from diethyl (L)-tartrate 14:508 Chiral ortho ester vinyl ethers 14:503 Chiral oxazolines 4:333 Chiral piperidines 10:671 synthesis of 10:671 Chiral precursors 6:298,299 aspartic acid as 6:298,299 (S)-3-hydroxybutyrate a 6:300,301 (R)-methyl-p-tolylsulfoxide 6:301,302 Chiral pyrethroid analogues 14:398-405 from thujone 14:398-405 synthesis of 14:398-405 via chiral cyclopropanation 14:401-405 Chiral reduction 1:482 Chiral reproduction 4:346 Chiral sesquiterpenes 14:406-425 synthesis of 14:406-425 via Robinson annulation reaction 14:406-425 Chiral shift reagent 4:326 Chiral steroid analogues 14:431-444 synthesis of 14:431-444 Chiral steroidal acetal 14:481,482 from (2R,4R)-(-)-pentanediol 14:481,482 from (2S,4S)-(+)-pentanediol 14:481,482 with organometallic reagent 14:481,482 Chiral sulfamyloxaziridines 4:489 asymmetric oxidation with 4:489 oxidation of sulfides with 4:489 Chiral sulfoxides 10:671-685 to 3,4-dihydro-6,7-dimethoxyisoquinoline 10:679-685 Chiral sulfoximines 10:671-679 intramolecular addition to 10:671-679 to 3,4-dihydro-6,7-dimethoxyisoquinoline 10:679-685
Chiral sulfur reagents 10:671-689 asymmetric synthesis with 10:671-689 Chiral sulphoxide 14:747 (-)-sibirine from 14:747 Chiral synthesis 12:477 of amino acid 12:477 of 1-(a-hydroxyalkyl)- 1,2,3,4tetrahydroiso quinolines 12:450 ofbioactive natural products 13:84-99 of bioregulators 6:537-566 of semiochemicals 6:537-566 Chiral synthon 1:482;20:817-881 by selective redox reaction 20:817-881 with yeast 1:482 for 2-aminoalcohols 12:416-425 Chiral tartaric amides 4:338,339 trans-acetalization of 4:338,339 Chiral template effect 12:489,500 Chiral templates 14:267-281 Chiral tertiary alcohols 14:491,492 asymmetric synthesis of 14:491, 492 from chiral a-keto acetals 14:491,492 Chiral titanium complexes 4:489 asyrmnetric oxidation with 4:489 oxidation of sulfides with 4:489 Chiral vinyl ether alcohols 14:486 from chiral cycloalkanone acetals 14:486 synthesis of 14:486 Chiral vinyl halide 12:35,36 coupling reaction of 12:35,36 with chiral a-methyl-substituted aldehyde 12:35,36 Chiral vinyl sulfoxides 10:671-679 intramolecular addition to 10:671-679 Chiral vinyllithium compounds 12:35-62 addition reaction of 12:35-62 Chiral ylide 4:125 fromL-malic acid 4:125 Chiral a,[~-ethylenic acetals 14:479 from C2-synmletric diols 14:479
169
with phenyl or alkenyl copperBF3 reagents 14:479 Chiral ~,[3-unsaturated acetals 14:478, 479 from (R, R)-(+)-N, N, N', N'tetramethyl tartaric acid diamide 14:478,479 with organo-aluminum reagents 14:478,479 Chiral (x-aldoxime-ether acetal 14:496 organocerium reagents to 14:496 Chiral (x-amino acetals 14:483 Lewis acid-mediated reaction of 14:483 with silicon-containing nucleophiles 14:483 Chiral (x-keto acetals 14:491,492 chiral tertiary alcohol from 14:491,492 from (-)-(2R, 3R)-2,3-butanediol 14:491 from (-)-(2S,3S)- 1,4-dimethoxy2,3-butanediol 14:491 Chiral (x-methyl-substituted aldehyde 12:35,36 coupling reaction of 12:35,36 with chiral vinyl halide 12:35,36 Chira113-1actams 12:121 synthesis of 12:121 Chiral co-cyano alcohols 14:475 from achiral (x-methoxycycloalkanone oxime acetates 14:475 synthesis of 14:475 via Beckmann fragmentation reaction 14:475 Chiral-o-quinodimethanes 14:502,503 asymmetric intramolecular 14:502,503 Diels-Alder reaction of 14:502, 503 with C2-syrnmetric acetals 14:502,503 Chiriquitoxin 21:73 Chiro-inositol 7:9 (x-glucosidases inhibition by 7:9 [3-glucosidases inhibition by 7:9 invertase binding with 7:10
(+)-Chiro-inositol 7:37,38 from conduritol [3 epoxide 7:38 Chiron approach 17:211 Sharpless oxidation 17:211 Chironomus tentans 29:32 Chironomus tentans epithelial cell line 29:32 Chirons 14:179;24:3 Chiroptical properties 2:153-173 in natural product structure determination 2:153-173 Chirotopicity 7:5 Chitanase 5:289 Chitin 5:280,287,289,291 ;23:107, 109;27:402;30:95 alkaline hydrolysis of 30:95 from shell of crabs 27:402 Chitin synthetase 1:399 Chitinases 22:75 Chitinasic 24:999-1001 enzymatic activity 24:999-1001 Chitin-chitosan 30:95-100 effect on blood pressure 30:95 effect on body weight in mice 30:98 effect on fat excretion 30:97 effect on free fatty acid 30:100 effect on hepatic triacylglycerol 30:100 effect on liver weight 30:100 effect on lipase activity 30:96 effect on pancreatic lipase activity 30:95,96 effect on parametrial adipose tissue weight 30:99 effect on serum triacylglycerol 30:100 effect on total cholesterol 30:100 in mice 30:99,100 in vitro 30:95 inhibitory effects of 30:96 intestinal absorption of 30:95 Chitobiose derivative 6:398,404,413 Chitobiosidases 21:224 Chito-oligosaccharides 7:33 Chitosan 4:720,276;23:109;25:396; 27:402-404,436;28:560,563 anti-obesity action of 27:402,403
170
anti-tumor activity of 28:560 biological activity of 27:404 effects on doxorubicin-induced gastrointestinal toxicity 28:563 of myelotoxicity 27:436 preventive effects of 28:563 prevention of 27:436 structure of 27:403 Chitosan inhibitory effects 28:561 on gastrointestinal toxicity 28:561 on immunocompetent organ toxicity 28:561 on myelotoxicity of 5-FU 28:561 Chitosome 5:276 Chitranone 2:212-215,754,755 Chitin 25:396 Chlamydia 26:1134 Chlamydia trachomatis 13:183 Chlamydomonas reinhardtii 26:364 Chlamydosporol 13:543-545 c~-Chlamydosporol 13:543 toxicity of 13:543 Chlamys hastata 25:813;28:717 Chlidanthine 20:359 Chlonostachys cylindrospora 26:451 Chloramphenicol 25:757;29:310 against bacillary dysentery 29:311 bacteriostatic effects of 29:311 biological activity of 29:310 biosynthesis of 29:310 effects on A erobacter ganera 29:311 effects on Bacillus ganera 29:311 effects on Diplococcus ganera 29:311 effects on pneumonia viruses 29:311 effects on Proteus ganera 29:311 effects on rickettsiae 29:311 effects on Staphylococcus ganera 29:311 effects on Streptococcus ganera 29:311 effects on trachoma viruses 29:311
effects on veneral lymphogranuloma viruses 29:311 effects on Vibrio ganera 29:311 effects on viruses 29:311 Chlordiazepoxide 21:673 Chlorella 25:429;30:762,764,766,787 detoxicating enzyme activity of 30:766 effect on plasma rennin activity 30:787 hypotensive components in 30:787 uses of 30:762 Chlorella cell 30:783,765 GABA in 30:784 glutamic acid in 30:783 Chlorella diet 30:763 effects of 30:763 on fecal excretion 30:763 Chlorella effect 30:787 on plasma rennin activity 30:787 Chlorella emersonii 26:358 Chlorella kessleri 25:430 Chlorella protothecoides 30:766 role in detoxication 30:766 Chlorella vulgaris 25:430,431,450, 452,453,455 ;30:761,762,766,782 against microbial infection 30:782 antitumor activity of 25:452 effect on gluthathione Stransferase 30:765 effect on skin papillomas 30:762 effects on fecal excretion 30:762 host defensive study of 30:761 immune-active acidic glycoprotein from 25:455 immunological effect of 30:782 mechanism of 30:782 pharmacological study of 30:761 role in dioxin excretion 30:762 role on inhibition of cytochrome P-450 30:766 role on inhibition of malondialdehyde levels 30:766 topical application of 30:762 use in colorectal carcinomas 30:762
171 Chlorella vulgaris strain CK 22 (CVs) 25:429-433,436,437,440,447,450 antitumor immuno-activity of 25:432 anti-peptide ulcer effect of 25:430 host-mediated activity of 25:431 immunopotentiating effects 25:429 Chlorhexidine 26:402 Chlorinated cylindrol B~ 25:790 Chlorinated malyngamides K 25:788 Chlorinated PCDD 30:764 c~-Chlorinating reagent 6:310 of sulfoxides 6:310 Chlorination 6:310,340;19:61 trans -5-Chloro- 1-menthen-8-ol 11:307, 308 3'-Chloro-2'hydroxy arguticinine 5:207 3-Chloro-2-hydroxy-arguticinin 9:66 1-Chloro-35-dimethoxy benzene 13:360 3-Chloro-3-deoxy-allo-derivative 14:163 2-Chloro-4-methylphenol 21:165 2-Chloro- 5-nitropyridine 12:309 (23 R)-6a-Chloro- 5 ~, 17c~-dihydroxy12[3-methoxy-1-oxo- 12,22-epoxyergosta-2,24-diene-23,26-olides 20:242 Chloro-8-hydroxy- 1,2-methylene-3[(1E,3E,5E)-5-methyl- 1,3,5heptatrienyl)] octahydroindolizidine 12:301 (1S,2R,3S,7S,8S,8aR)-7-from indolizomycin 12:301 5-Chloro-8-quinolyl 4:286 3'-Chloro-abscisic acid 27:353 Chloroacetoxylation 16:443 Pd(II)-catalysed 16:443 9-Chloroacronycin 20:792 (c~-Chloroalkyl) boronic esters 11:409, 410 synthesis of 11:409,410 Chloroamine 11:307,308 N-Chloroamines 6:437 from N-chlorosuccinimide 6:437 Hoffmann-Loeffier photocyclization of 6:437
Chlorobactene 7:339,361-363 2-(3-Chlorobenzoyloxy)- 1-(2-methoxyphenyl)-2-(4-ethoxyphenyl) ethanol 30:223 structure of 30:223 (Z)-3-Chloro-butenoate 20:830 (Z)-3-Chloro-cinnamate 20:830 (cz-Chlorocrotyl) boronic ester 11:424 (methoxycrotyl) boronic ester from 11:424 from allylic alcohol 11:424 c~-Chlorocyclopentene carboxylate esters 8:225 Favorskii rearrangement of 8:225 3-Chlorodehydroleucodin 29:90 activity in NFkB assay system 29:90 7-Chlorodehydronoraporphine 16:516 6-Chloro-D-tryptophan 15:35 2-Chloroethylphosphonic acid 25:509 Chloroformate ester-induced reaction 6:477,486 ring destruction by 6:477,486 Chlorogenic acid 15:36;22:167,346, 645,663;23:740,744,749,753;25:663, 655,657,667,919-921,930,932-935, 937-940,942-947 ;26:695 antioxidative properties of 25:919,930,935 (+)-Chlorogenic acid 27:421 biological activity of 27:421 3-Chloroguaiazulene 14:331 Chlorohydrins 1:451 Chloroissoclimide 25:270 Chloroklotzchin 7:214 from Artemisia klotzchiana 7:214 p-Chloromercuribenzoate 27:736 Chloromercuric method 4:233 in synthesis of 6-deoxynucleosides 4:233 (Chloromethyl) zinc reagent 14:490 2-Chloromethyl-4-nitrophenylphosphorodichloridate 8:73 2-Chloromethylbenzoate 5:827,828 Chloromethylene dimethylforminium chloride 3:212 6-Chloromethylsalicylate 5:828
172 Chloroorcinols 25:757 m-Chloroperbenzoic acid 2:90-103 Chloroperoxidase 25:767 3-Chloroperoxybenzoic acid 22:203 o-Chlorophenyl group 4:269 p-(Chlorophenyl) sulfinyl acetate 21:380 bis-2-Chlorophenylhydrazones 12:379 Chlorophora tinctoria 22:360;29:582, 573,580,585 Chlorophyceae 6:134,147 Chlorophylls 7:98;20:760-762 Chlorophyllin 30:765 with dioxins 30:765 Chlorophylls a,b,c 20:728 Chlorophyta 27:735 3-Chloroplumbagin 2:212,214,754 Chloropromazine 12:387 (S)-(R)-Z-Chloropropionic acid 6:386 with methyl 2-acetamido-4,6-Obenzylid-ene-2-deoxy-~x-Dglucopyranoside 6:386 Chloropseudomonas ethylica 7:363 Chloropuupehenone 15:299 Chloropyridine 25:792 6-Chloropyridine-3-carboxylate 20:864 to 3-hydroxymethyl-6-chloropyridine 20:864 Chloroquine 20:517,518;22:147;23:301; 25:335,336,337,343,344,345,346, 347,348,349,352,360;26:1030,1035, 1037,1038,1063,1065;30:596 Chondroitin sulfate 30:101-103,105, 107,108,109,397 D-glucuronic acid 30:101 D-N-acetylgalactosamine 30:101 Chloroquine diphosphate 7:393 Chloroquine Fe(III) PPIX 25:346 Chloroquine potentiating antiplasmodial activity 30:597 in vivo 30:597 of laudanosine 30:597 Chloroquine sensitivity 30:595 in resistant Plasmodium species 30:595 Chloroquine-enhancing activity 26:1065 Chloroquine-enhancing effectiveness 30:596
of alkaloids 30:596 Chloroquine-pyrollidinyl 25:344 Chloroquine-resistant parasites 25:352 Chlorosampangine 23:6 N-Chlorosuccinimide 6:310;12:487 DMSO reaction with 6:310 monochlorinated sulfoxide from 6:310 N-chloroamines from 6:437 Chlorosulfolipid 28:655 stereochemistry of 28:655 Chlorosulfonyl isocyanate 4:475,477; 22:275 cycloaddition with 4:475,477
1-acetoxy-2-methylbutadiene
with 12:150,151 [2+2] cycloaddition of 4:475; 12:150,151 Chlorotrimethylsilane 19:445
Chloro-tris-( triphen yphosphine )
rhodium decarbonylation with 5:802 Chlorowithanolides 20:223 Chlorphenamine 26:401 Chlorproguanit-dapsone 26:783 4-Chlorugenic acid 23:757 Chocolate spot disease 4:590 Cholecalciferol (vitamin D3) 9:509-528 Cholecystokinin 18:824;24:910-913 as putative satiety factor 24:910 effect on contraction 24:910-913 effect on relaxation 24:910-913 related peptides 24:910-913 Cholecystokinin effect 27:799,800 Cholelithiasis 27:378 Cholelithiasis therapy 27:378,382 Cholera toxin 25:521,538 Choleretic 22:346;24:799 Achyrocline satureioides as 22:346 biological activity 24:799 Choleretic activity 23:356;26:399,400, 414 of isofraxidine 23:356 5,c~-Cho 1est- 14-dne- 3 [3,6c~,24-trio1 7:288 Cholest-5-en-3[3-ol (cholesterol) 9:5,37, 447,449;9:454,461,462
173 Cholest-5-ene-24-0ne-313,7oc-diol 20:477 Cholest-5-ene-3ot,4[3,21-triol 3,21disulphate 15:98 from Ophiura sarsi 15:98 Cholest-5-ene-3 [3,7ot,diol- 1-oxo 20:707 from Salvia glutinosa 20:707 Cholest-7-enyl linolenate 9:470 5 oc-Cholesta-9(11),24(25)-dien-3 ~, 6or 20,22-tetraol aglycone 15:49 5cx-Cholestan-3-one 2:168 octant rule in 2:168 5cc-Cholestan-3 [~,6cc,8,15o~, 16[3,25hexaol 15:77 from Protoreaster nodosus 15:77 5ot-Cholestane 20:248 Cholestane glycoside 21:636 5ot-Cholestane-3[3,5,6[3,9-tetrol 23:159 5 [3-Cholestane-3 cc,4a, 11 [3,12[3,21pentaol 3,21-disulphate 15:96 5 [3-Cholestane-3 oc,4c~,1113,21-tetraol 3,21-di-sulphate 15:96 (25R) 5 [3-Cholestane-3cx,6[3,15ct, 16[3,26pentaol 15:75 (25R) 5c~-Cholestane-3[3,5,6[3,15c~,1613 26-hexaol 15:75 (24S) 5c~-Cholestane-3 f3,6ct,8,15 [3,24pentaol-aglycone 15:61,68 Cholestanepentols 17:214 5a/513Cholestanols 9:454 steryl palmitates of 9:454 Cholestanyl palmitate 9:454 Cholesterol (cholest-5-en-3[3-ol) 9:5,37, 447,449,454,461,462,464,470 Cholesterol acyltransferase 25:722,797 Cholesterol biosynthesis 23:480 inhibition of 23:480 Cholesterol oxides 24:351-398 biological activities of 24:353-376 biosynthesis of 24:358-360 effect on activity of HMGR 24:373-376 role in coronary heart disease 24:376-381 Cholesterol synthesis inhibition 25:525
Cholesterol variation number (CVN) 24:351,368,369 Cholesterol-(7-dehydrocholesterin) 9:510,512,521 Cholesteryl 3,4,6,-tri-O-acetyl-[3-Dglucopyranoside 8:363,365,366 Cholesteryl acetate 9:464,465 Cholesteryl arachidonte 9:454,459, 461,467 Cholesteryl butyrate 9:464,465 Cholesteryl caproate 9:464,465 Cholesteryl elaidate 9:457 Cholesteryl esters 9:450,453,457,462, 466-478 Cholesteryl laurate 9:465 Cholesteryl linoleate 9:456,461,464,467 Cholesteryl myristate 9:460,465 Cholesteryl oleate 9:456,457,464,467 Cholesteryl palmitate 9:454-456,459, 461,464,465,467, 472,477 Cholesteryl palmitoelaidate 9:457 Cholesteryl palmitoleate 9:456,457,467 Cholesteryl stearate 9:456,461,465 Choline 5:752; 24:1007,1008;25:475, 476 occurrences of 24:1007,1008 Choline sulfate 24:1007,1008 occurrence of 24:1007,1008 Cholinergic activity 21:736 Cholinergic antagonists 21:102,109 Cholinergic decumbenines 21:733 Cholinergic receptor 21:51 ;22:16 Cholinergic transmission 22:15 Cholinesterase 7:18 Cholinesterase inhibitor 21:748,749 Cholinestrase inhibitor huperzine A Cholistane-3fl,5 t~,6p-triols 24:352 cytotoxicity effect of 24:352 Chondocurine 25:472,476 Chondodendron autumnale 25:476 Chondodendrum tomentosum 13:631 Chondostoreium purpureum 21:196 Chondria armata 17:21 ;26:479 Chondria baileyana 26:479 Chondria californica 25:842 Chondria oppositiclada 6:40 cycloeudesmol from 6:40 Chondria sp. 26:488 Chondria tenuissima 25:249
174 Chondriamide A&B 26:488 Chondrilla sp. 18:718 Chondrillin 5:353,354,718;23:211 Chondrococcus hornemanni 5:343 Chondroitin sulfate 30:101-103,105, 107,108,109,397 effect on 2-monooleoylglycerol uptake 30:103 effect on adipose cells diameter 30:109 effect on body weight 30:107 effect on fatty acid uptake 30:101 effect on glucose uptake 30:101 effect on hepatic triacylglycerol 30:109
effect on liver 30:108 effect on palmitic acid absorption 30:103 effect on pancreatic lipase activity 30:101,102 effect on parametrial adipose tissue 30:108 effect on rat plasma triacylglycerol levels 30:105 in HIV therapy 30:397 in mice 30:107,108 in vitro 30:101,103 inhibitory action of 30:101 Chondromyces sp. 25:730 Chondrosia collectrix 18:719 Chonistoneura fumiferana 26:876 Chorda 26:1121 Chordata 21:3 Choriaster granulatus 7:299 Choriocarcinoma 14:805 vinblastine for 14:805 vincristine for 14:805 Chorisia speciosa 26:1157 Chorismate mutase 11:188,189 prephenic acid from 11:188,189 Chorismic acid 11:187 anthranilic acid from 11:187 from 5-enolpyruvylshikimate 3phosphate 11:187,188 phenylalanine from 11:188 tyrosine from 11:188 Choristoneura fumiferana 22:388
6-Choro-9-(3-deoxy-[3-D-xylohexopyranosyl) adenine 4:232 Christofin 26:659 Chromaggin granules 25:536 Chroman 1:644,645 enantioselective synthesis of 1:644,645 Chromanes 4:391 from isoprene 4:391 from phenols 4:394 in prenylation methods 4:394-396 synthesis of 4:374 Chromanones 9:450 Chromatiaceae 7:361 Chromatogaphic analysis 9:450-453 by adsorption chromatrography 9:450-453 by gas chromatography 9:453-460 ofsteryl esters 9:447-486 Chromatogaster scutellaris 6:455-458 Chromatographic analysis 21:535 Chromatographic methods 21:507,525 Chromatographic techniques 30:591 fractionation 30:591 Chromazonarol 15:291,298 ent-Chromazonarol 15:291,299 Chromenes 2:126,368,369,372,373, 376,409,410;13:356,358 Chromenes 7:409,410;20:282;23:342 Chromis chromis 21:364 Chromium (II) reagents 3:81 Chromobacteria 21:298 Chromodoris cavae 9:4,13 Chromodoris elisabethina 28:650 icthyotoxic latrunculin A from 28:650 Chromodoris funarea 17:9,10 Chromodoris lachii 17:13 Chromodoris macfarlandi 17:11 Chromodoris maridadilus 6:69 Chromodoris norrisi 17:12 Chromodoris sp. 17:12,14 Chromodorolide A 9:4;17:13 Chromodorolide B 17:13 Chromodris hamitoni 25:735
175
Chromogenic assay 30:834 of chromogenic substrate 30:834 specificity of 30:834 Chromogenic substrates 7:53 Chromomycins 4:245;17:37 Chromomycin A3 3:173 Chromones 9:113-116;17:574;22:475; 24:499-503 as antiviral compound 24:499-503 Chromone alkaloids 21:123-153 biological activity of 21:123 Chromonocoumarins 7:415 Chromophore 30:534 polarisation of 30:534 Chromophoric oligopeptides 30:835 role in assay 30:835 Chromophoric procedure 30:834,835 role in assay 30:835 Chromosome 30:379 Chromosome exchange 27:304 Chromosome mutation test 27:303 epi-8-Chromozonarol 5:437 antimicrobial activity of 5:437 Chromozym TH 30:840 Chronic diabetes complication 30:697 cataracts in 30:697 peripheral neuropathy in 30:697 retinopathy in 30:697 Chronic experiment 27:313 Chronic inflammation alleviation 24:887-895 by medicinal plants 24:888-895 by neolignan 24:888-890 Chronic leukemia 26:925 Chronic pain model 30:203 activity of ginseng in 30:203 Chronic painful inflammatory diseases 30:206 pro-inflammatory substances in 30:206 Chronic rheumatoid arthritis 30:204 monodesmodides in 30:204 treatment of 30:204 use ofhederaginin 30:204 Chronic toxicity studies 27:308 Chronic viral hepatitis 25:463 Chryosplenoside A 5:682 Chrysamin 27:551
Chrysanolide 27:559 Chrysanthellin 15:209 Chrysanthellin B 15:210
Chrysanthemum cinerarifolium 28:384 pesticide properties of 28:383 secondary metabolites from 28:384 Chrysanthemumfrutescens 9:317 Chrysanthemum golden 20:246 Chrysanthemum mortifolium 22:122; 29:586-588 effects on CHY 29:586 Chrysanthemum parthenium 27:376 Chrysanthemum sp. 7:427 trans-Chrysanthemyl alcohol 7:100,101 Chrysanthemyl alcohol 7:126 cis-Chrysanthenol 9:530 Chrysanthenum coronarium 25:944 cis-Chrysanthenyl acetate 9:530,536 Chrysartemin B 7:235 Chrysazine 25:543,544 Chrysentunone 27:592 Chrysin 26:746,762 Chrysin (5,7-dihydroxyflavone) 29:572, 577 effects on aminopeptidase N 29:577 effects on HIV- 1 protease 29:572 Chrysocephalum ambiguum 25:251 Chrysochromulina species 6:135 Chrysoeriol 7:226;23:742;26:746 Chrysoeriol-7-O-p-coumaroyl glucoside 5:623 Chrysomma sinensis 5:837 hemoglobin components of 5:837 Chrysomycin 10:347 Chrysophanic acid 22:609,617,618; 23:537 Chrysophanoic acid 25:543 Chrysophanol 22:610;23:537,797; 26:637 Chrysophyceae 6:134,135 Chrysoplenium pseudofauriei 5:678 Chrysospermins 26:482 Chrysosplenium americanum 5:682 Chrysospleniumflagelliferum 5:682 Chrysosplenium grayanum 5:682
176 Chrysosplenol-D 7:413 antimicrobial activity of 7:413 Chrysosplenoside E 5:682 Chrysosplin 5:682 Chugaev reaction 4:45 Chukrasia tabularis 9:105 Chymacyparis taiwanesis 29:698 et-Chymotrypsin 2:35 Chymotrypsin 13:56,519,536,537; 30:830,831,837 homologous sequences of 30:831 Leu-X cleavage site of 30:837 Phe-X cleavage site of 30:837 Trp-X cleavage site of 30:837 Tyr-X cleavage site of 30:837 Culmoriuns 13:519,536,537 from Fusarium culmorum 13:536 synergistic effects 13:536 toxicity of 13:536 Chytridiomycetes 9:202 Chytridiomycota 22:246 Chytrids 22:246 Cibarian 27:522 Cicer arietinum 18:719;25:93;26:1268, 1288 Cichoriin 12:145 inhibitor of dehydropeptidase (DHP-1) 12:145 Cichorin 26:314 CIDMS/MS 19:643 Cidofovir 24:486,487 as anti-viral agent 24:486,487 Cieplak's theory 29:127 in sesquiterpenoids drimane-type synthesis 29:127 Ciguatoxins 21:300;25:732,733 Cilastatin 4:432 Cimetidine 25:612 Cimicifuga 25:180;29:582 Cimicifuga dahurica 22:516 Cimicifuga racemosa 27:277 Cimicifugic acid A (phenylpropanoid ester) 29:582 effects on collagenase 29:582 Cimifuga sp. 27:395 Cinachyra sp. 19:581 Cinachyrella alloclada sp. 26:67
Cinachyrolide A 19:580;25:759 13C-INADEQUATE 9:143-146 Cinchomeronic anhydride 6:510,511 Cinchona 21:488;22:146;516;26:835, 836 Cinchona alkaloids 7:444,62 Cinchona ledgeriana 26."144 Cinchona officinalis 25:476 Cinchona robusta 30:344 suspension culture of 30:344 Cinchona succiruba 26:779,780,820 antimalarial activity of 26:779 Cinchonamine 22:147 Cinchonidine 21:96,97,102,108,109; 22:146;26:836 1,8-Cineole 9:530,536;15:225,227; 21:595,621 Cineole 21:595,599,615 1,8-Cineole 25:140;29:83 activity in TNF assay system 29:83 Cinerin I 27:588 Cinerin II 27:588 Cinnabarin 26:1012 Cinnabarinic acid 26:967,1020 Cinnamaldehyde 21:621,622 trans-Cinnamaldehyde 27:16,33 structure of 27:33 Cinnamate 4-hydroxylase (C4H) 23:337 Cinnamate 4-hydroxylase 5:467,468; 25:653,660 Cinnamates 9:530,536 Cinnamic acids 5:459,467-470,473,479; 20:271 ;23:337,744,779;25:652,653, 925;28:261 caffeic (3,4-dihydroxycinnamic) acid as 28:261 (E)-Cinnamic acid 5:467 Cinnamolide 2:287,288,414 (+)-Cinnamolide 6:28 (+)-polygodial from 6:28 Cinnamomm osmophloeum 15:29 Cinnamomum camphora 22:516; 25:140,156 ;26:1039 ;28:419 as anticonvulsant 22:516 for hysteria 22:516 for epilepsy 22:516
177 Cinnamomum cassia 22:427 epicatechol from 22:427 epicatechol-O-glucoside from 22:427 Cinnamomumjaponicum 28:419 Cinnamomum osmopholeum 27:16 trans-cinnamaldehyde from 27:16 Cinnamomum philippinense 26:240,249 cinnamophilin from 26:240,249 meso-dihydroguaiaretic acid from 26:240 Cinnamomum sieboldii Meisner 15:33; 27:18,35 Cinnamtannin B- 1 from 27:18,35 Cinnamtannin D- 1 from 27:18,35 Cinnamomum sp. 24:275;29:588 Cinnamon bark 28:259 gallic acid from 28:259 salicylic acid from 28:259 syringic acid from 28:259 Cinnamonin 25:395 Cinnamonium camphora 18:558 (-)-dimethylmatairesinol from 18:558 Cinnamonum camphora 21:621 ;27:377 Cinnamonum zeyIanicum 27:377 Cinnamophilin 26:240 as PAF-induced inhibitor 26:240 Cinnamophilin 26:240,266,267 10-Cinnamoyl baccatin III 11:61 Cinnamoyl CoA 25:655 Cinnamoyl ester of crassin 8:15 antileukemic activity of 8:15 Cinnamoyl-CoA reductase 5:470 Cinnamoylcocaine 22:722 6N-Cinnamoyl- [3-naltrexamine (CNX) 30:812 molecular model of 30:812 Cinnamtannin 1 27:18,35,36 structure of 27:36 Cinnamtannin B-1 15:33 Cinnamtannin D-1 15:33;27:18,35,36 structure of 27:36 Cinnamyl alcohol dehdrogenase 5:470; 27:763
Cinnamyl alcohols 5:459,463,467, 469-471,473,474,495,497 ;27:760 polymerization of 27:760 Cinnzeylanine 26:853 Cinnzeylanol 26:850 Cinnzeylanone 26:850,853 Ciocalypta sp. 17:16;21:349,355 Ciona intestinalis 5:405,408,249 Ciona savignyi 25:784 Circadian activity 30:369 abnormalities of 30:369 effect on anorexia 30:369 effect on bipolar disorder 30:369 effect on bulimia 30:369 effect on obsessive compulsive disorder 30:369 effect on panic disorder 30:369 effect on schizophrenia 30:369 effect on seasonal affective disorder 30:369 effect on unipolar depression 30:369 Circular dichroic power 17:48 Circular dichroism 2:153,159-61,165, 166,169-173,226,227,137,140, 149,264,390,539,542;15:193,194; 423-438;22:374;26:550,551 ;30:584, 586 of (7R,8S,7'R,8'R)-(+)-7'-acetyl5 '-metho xyp icrop o doph yllin 30:586 of tetrahydrobenzylisoquinolines 30:584 Circular dichroism method (octant rule) 14:743 Circular dichroism spectroscopy 21:403 Circularly polarized light 2:154 Cirrhosis 30:406 Cirsilinol 7:226 Cirsiliol 30:727 structure of 30:727 Cirsimaritin 7:226;30:726,727,748 antispasmodic activity of 30:748 structure of 30:726 Cirsitiol 20:712 from Salvia montbretii 20:712 Cirsiumjaponicum 26:436 Cis and trans-deethyleburnamonines 25:19
178
Cis decalin-tetrahydrofuranyl kalihinol 25:855 Cis-5-hydroxy-4(4'hydroxy-3 '-methoxyphenyl)-4-2"-imidazoyl)-l,2,3trithiane 25:837 Cis-cis-ceratospongamide 25:904,905 Cis-deethylburnamonine 25:6 Cis-deethyldihydroeburnamenine 25:6 Cis-pentacin 22:285,299;23:349 Cisplatin 21:136;26:213;28:559;30:56 cancer chemotherapy drug 30:56 for cancer chemotherapy 28:559 side effects of 30:56 Cissampelos pareira 29:578 Cissua integrifolia 22:517 for epilepsy 22:517 Cistaceae 25:249,252,253 Cistanche deserticola 25:468,476 Cistrus hirusutum 19:246 Cistus clusii 25:250 Cistus creticus 25:246,249,250,252, 255,256,257,266 Cistus creticus ssp. erioocephatus 25:259 essential oils of 25:259 Cistus incanas ssp. creticus 25:258,266 Cistus ladaniferus 25:252 Cistus laurifolius 25:250 Cistus palinhae 25:250 Cistus spp. 29:581 Cistus symphylifolius 25:250 essential oils of 25:255 Citbrasine 13:350 from Citrus sinensis 13:350 Citeromyces matritensis 5:283 Citeromyces sp. 5:280 Citorellamine 25:837 Citpressine I 13:350 from Citrus depressa 13:350 Citpressine II 13:350 from Citrus grandis 13:350 Citracridone I,II 13:348,349 from Citrus depressa 13:348,349 Citral 13:332;20:5;21:595;25:132, 133,136,137,143;29:83 activity in skin-1 assay system 29:83 activity in TPA assay system 29:83
Citramalic acid 8:305 Citranaxanthin 20:606,607,757 Citranellae 25:132,140 Citraurin 20:757-759[~Citreorosein 22:609,610 (-)-Citreoviridin 10:439 Citreoviridine 18:176 Citric acid 7:180;21:192 in mangrove plants 7:180 Citric acid cycle 9:554;21:302,317 Citrobacter 12:63 Citrobacter freundii 26:402 Citrol 25:136,137,140 ~-Citromycinone 14:14 T-Citromycinone 14:8-10 synthesis of 14:8-10 Citronellal 8:47;25:128 S-Citronellal 17:610 (R)-(+)-Citronellal 19:215 R-(+)-Citronellal 8:43-46,57,258,266 S-Citronellate 15:229 (-)-Citronellene 17:605 R-(+)-Citronellic acid 16:344 Citronellic acid 21:589;25:133,136; 26:86 (+)-Citronellol 1:451 ;2:167,168,17,605 (S)-(-)-Citronellol 11:343,344,367; 16:192 (3R)-(+)-Citronellol 13:122,123 (R)-Citronellol 18:26;19:43 Citronellol 7:105,125;21:587,589,590; 25:132,133,136,137,140;28:426 as bioactive monoterpenoid 28:426 Citronellyl acetate 25:136 Citropten 18:979 L-Citrulline 26:931 Citrullus colocynthis 5:750;20:13; 22:517 as antiepileptic agent 22:517 Citrullus vulgaris 29:614 Citrus auranhtium ssp. amara 27:372375,377 petitgrain oil from 27:372-375, 377 Citrus aurantium 15:5;22:517;25:476; 27:17,377;29:573
179
neohesperidin dihydrochalcone from 27:17 Citrus buxifolia 13:350 atalfoline from 13:350 Citrus decumana L. 13:348,349;22:517 Citrus depressa 13:348 citracridones I,II from 13:348 citpressine I from 13:348 Citrus flavonoids 26:744 Citrus genus 27:377 Citrus grandis 13:348,349;22:517 baiyumine A from 13:348,349 baiyumine B from 13:350 butanine from 13:350 citpressin II from 13:350 grandisines I,II from 13:350 grandisinine from 13:350 honyumine from 13:348,349 prenyl-citpressine from 13:350 Citrusjunos 13:348,349 junosidine from 13:348,349 Citrus latifolia 27:372,377 Citrus limon 23:747;25:594;27:375,377 Citrus maxima 22:517 for epilepsy 22:517 for convulsive cough 22:517 Citrus natsudaidai 13:350;27:17,375 natsucitrines I,II from 13:350 Citrus oils 27:372 Citrus paradisi 14:450;23:747 eudesm-11-en-4-ols from 14:450 (+)-intermedeol from 14:450 naringin dihydrochalcone from 27:17 Citrus peel oils 25:145 Citrus reticulata 23:747;27:375;29:573 Citrus sinensis 13:348,350;23:747; 27:375 citbrasine from 13:350 citrusinines I,II from 13:348,350 Citrus sp. 5:651 ;25:128,266,267 Citrus unshiu 18:682 Citrusin B 20:697 Citrusinines I,II 13:348,350 from Citrus sinensis 13:348,350 Civet acid 1:637,638 enantioselective synthesis of 1:637,638
Civetone 8:223,224 acyloin condensation of 8:224 from Viverra civetta 8:219 Wittig reaction of 8:223,224 Ciwujianosides 15:191 Cladinose 13:155,156,158,159,162 L-Cladinose nucleosides 4:256 Cladobotrin 26:449 Cladobotryum rubrobrunnescens (Hyphomycetes) 26:449 Cladobotryum varium 26:449 Cladonia alpestris 5:310,313 Cladonia confusa 5:310,313 Cladonia crispata 5:310 Cladonia mitis 5:310 Cladonia rangiferina 5:310 Cladonia sp. 5:310 Cladonia squamosa 5:310 Cladophora fascicularis 5:367 Cladosporin 11:193;15:382,385-387; 23:343,348 Cladosporium cladosporiodes 11:193; 15:386,193;22:627;23:343,535; 26:553 Cladosporium coccodes 25:305 Cladosporium colocasiae 26:1091,1093 Cladosporium cucumerinum 7:406,409, 411,413 ;15:64,415,421,433 ;21:189, 257,266,275,277,281,283,284,662; 23:347 ;25:776;26:333,673 Cladosporium fulvum 25:302,308,398, 399,400 Cladosporium herbarum 20:245;2:475; 5:302 Cladosporium phlei 21:189 Cladosporium sp. 5:301,325,328,370; 25:145;26:1128 Cladosporium sphaerospermum 26:228 Cladosporium suaveolens 13:309-311, 313,315 Cladosporium wemeckii 5:301 Cladosporum herbanum 7:119 Cladrastis lutea 5:678,683 Claisen condensation 1:49,99,100,174, 243,410;11:114;19:35;20:740; 26:1237 of dicarboxylic acid derivatives 11:114
180
with acetoacetate dianion 11:114 Claisen cyclization 9:341 Claisen disconnection 19:228 Claisen ester enolate rearrangement 10:339 Claisen orthoester rearrangement 26:72 Claisen reaction 6:36 in poitediol synthesis 6:36 Claisen rearrangement 1:43,45,78,91, 172,173,180,181,230,243,251,457, 459,471,563 ;8:180;11:471 ;13:29,30, 135,142,358,417,437,438,443,613; 16:260,340,439,471,623,627,703, 712;19:229;20:66,67 ;24:47,756,758 [3,3]-Claisen rearrangement 10:416-426 applications of 10:416-426 asymmetric quaternization with 10:426-428 carboxylic acid anhydride variation of 4:375 Eschenmoser modification 3:230 in (+)-9-isocyanopupukeanane synthesis 6:82,83 in (+)-africanol synthesis 6:5 in (+)-sinularene synthesis 6:78, 79 in lactone synthesis 3:252-255 indolo [2,3-a] quinolizidines by 14:722-724 internal asymmetric induction 3:234 Ireland modification 3:77,228 of 1,5-anhydro-4,6-O-benzylidene-D-ribo-hex- 1-enitol 10:420 ofallyl ester 14:738 of allyl phenyl ethers 4:368 of carbohydrate derivatives 10:416-426 of carbohydrates 3:226 of chiral allylic alcohols 10:418 of cis 2,5-disubstituted dihydrofuran 10:423,424 of dihydropyran derivative 10:425 of E (3-hydroxy- 1-propenyl)- ~D-glucopyranose tetra acetate
10:422 ofN,O-ketene acetals 3:232 of oxygen substituted systems 3:237-248 of silyl ketene acetals 422,423 of vinyl ether derivative 10:420 of vinyl ketene acetals 10:234, 235 of xanthones 4:368,370-372 ortholactone procedure 3:236 regioselectivity of 4:368,368 Clarithromycin 13:164,183;25:617; 25:617 Clary sage oil 25:252 Class III peroxidase 27:737 Classical cannabinoids 30:195,198 structure-activity relationships of 30:198 Classical Nazarov reaction 14:612 Classification 6:546;28:281 ;30:198,560 by sporulation 6:546 of cannabinoid ligand 30:198 of ellagitannin oligomers 28:281 of ellagitannins 28:281 of fungi 6:546 of gallotannins 28:281 of galloylated proanthocyanidins 28:281 of macroline -related alkaloids 13:384-396 of proanthocyanidins 28:281 of prodelphinidins 28:281 of Rabdosia diterpenoids 15:112 of Strychnos alkaloids 1:32 of tannins 28:281 Clatha palustris 7:427 Clathramides 25:757,777 Clathria pyramida 6:351 ;28:715 Clathria sp. 28:702 Clathridine 17:18 Clathridine B 17:18 Clathrina clathrus 25:870 Clathsterol 28:702 against HIV- 1 reverse transcriptase (RT) 28:702 Clausantalene intermediate 4:675 Clausarin 4:374,375 synthesis of 4:374,375
181 Clausena anisata 22:517 as anticonvulsant 22:517 Clausena harmandiana 9:400 Clausena heptaphylla 2:118 Clausena indica 2:118 Clausena pentaphylla 2:118 Clavalanine 16:708 Clavaric acid 24:440 inhibition rHFPTase 24:440 structures of 24:440 Clavelina cylindrica 25:793,859;28:644 cylindricine F from 28:644 genistic acid 28:259 Clavelina lepadiformis 29:426 Clavelina picta 10:249;29:426 Clavepictines A,B 10:249 Claviceps 21:91,488 Claviceps eurotium 9:203 Claviceps fusiformis 5:278 Claviceps purpurea 13:631 Claviceps sp. 5:278;11:200 Clavicipitales 9:203 Clavosine 27:878,879 Clavukerin A 21:292 Clavularia inflata 6:77 (+)- 12-acetoxysinularene from 6:77 Clavulones 19:551 Cleavage ofolefins 1:445 with t-BuOOHg/HsIO6 1:445 with Mo (CO)6 1:445 Cleavamine-type alkaloids 5:103 capuronine 5:103 (+)-20R- 15,20-dihydrocleavamine 5:103 14S,20R-velbanamine 5:103 Cleislopholis staudtii 22:400 Cleistanthane skeleton 19:395 Cleistanthus collinus 26:204 cleistanthin A&B from 26:204 Cleistopholis patens 2:340;22:400; 23:4,341 Clematis hexapetala 19:125 Clematis sinensis 20:539,540 Clementine 23:747 Clemmensen reduction 12:240,279,697, 698 ;15:197,198 ;24:205 Clemmensen-type deoxygenation 19:18 (+)-Clemeolide 18:28-32
Cleomane 23:489 Cleome cileata 22:517 Cleome icosandra 18:28;23:487 Cleome viscosa 18:28 Cleomeolide 23:488,491 transformation of 23:488,491 synthesis of 23:488,491 Cleomiscosin A 5:5;7:377 Clerodane 25:241 Clerodane cajucarinolide 29:100 activity in TLO assay system 29:100 Clerodane diterpenes 24:280-282; 30:748 principles of spasmolytic drugs 30:748 structure of 30:748 neo-Clerodane diterpenoids 23:592 neo-Clerodanes 23:601 13C-NMR data of 23:604 lH-NMR data of 23:604 structures of 23:603 3~-H-neo-Clerodanes 23:607 13C-NMR data of 23:607 ~H-NMR data of 23:607 Clerodane-type diterpene 2:280 CisClerodendron inerme 20:539,540 Clerodendron wildii 21:662 Clerodendrum uncinatum 7:408,417, 423; 23:343 Climacostol 30:140,162 synthesis of 30:140 Clinical chemoprevention trials 30:592 Clinical development 30:5 for colon cancer 30:5 for multi-drug resistant cancers 30:5 for ovarian cancer 30:5 for taxol-resistant breast cancer 30:5 Clinical studies 30:842 of thrombolytic agents 30:842 Clinical trials 21:750,754 ofBtg A 21:754 ofHup A 21:748-750 Clinical usage 21:138 of flavopiridol 21:138 C-linked glycosyl acetylenes 10:358 from glycosylhalides 10:358
182
Cliona celata 5:411 Cliona chilensis 25:778 Clionamide 5:411 Clitocybe acromelalga 19:163;26:479 Clitocybe geotropa 18:813,814 Clitocybe nebularis 18:813,814 Clitocybe subilludens ( Omphalotus subilludens) 29:296 biosynthesis in 29:296 Clivia miniata 20:351 ;26:619,620 Clivonine 26:620 Clofazimine 2:424 Clomipramine 22:672 Clonal expansion 26:921 of antigen-specific T 26:921 Cloned mammalian adenylylcyclases 27:825 Clonidine 25:530 Cloning 7:114-117 Clonogenic assays 21:259 Closantel 26:440 Clostridium 13:303 Clostridium difficile 5:601 Clostridium formicoaceticum 20:821, 824,861-862,867,869,870,871, 873-879,881 Clostridium kluyveri 20:821,824,831, 834 Clostridium perfringens 5:601,71,81, 86,87;16:108;25:925 Clostridium tetanomorphim 9:598,601; 20:821,824,861-863,867,869,870, 871 Clostridium tyrobutyricum 20:821,824, 829,830,834-839,863,873-877; 25:147 Clotting disease 30:839 fibrinolytic agent in 30:839 Clove buds 28:259 protocatechuic acid in 28:259 syringic acid in 28:259 Clusia nemorosa 22:659 Clusia plukenetii 22:660 Clusia portlandiana 22:659 Clusia rosea 22:659 Clusioidea 30:604 CMB 4:368,369,372,373 CMTP 21:416
CMV infection 30:405 chemotherapy of 30:405 CNBr-induced reaction 6:472-474,476, 477,484,486,488,489,491,492,495, 496 Cnemidocarpa bicornuta 25:765 Cnestis ferruginea 22:517 Cnidaria 21:3,272 Cnidaria 23:153;28:646 corals among 28:646 gorgonians among 28:646 hydrozoans among 28:646 ellyfish among 28:646 living species of 28:646 sea anemones among 28:646 soft corals among 28:646 13C-NMR 5:533,534 incremental effects of 9:275-280 of ~-pipitzol benzoate 5:787 of (+)- 1-acetoxypinoresinol 5:533,534 of (+)- 1-fraxiresinol 5:535 of (+)- 1-hydroxypinoresinol 5:534 of (+)-epi-pinoresinol 5:526 of (+)-pinoresinol 5:526 of 10-demethoxykopsidasinine 5:52,54 of 11-O-methylcaesalpin 5:24 of 13-epi- 11-O-methylcaesalpine 5:24 of 2'-hydroxyflavone 5:4 of 2'-methoxyflavone 5:14 of 4-hydroxy-sapriparaquinone 5:36 of 6-isocedrol 5:789 of acteoside 5:507 of alloaristoteline 11:314 of aquillochin diacetate 5:9 of arguticinin 5:203 of argutinin 5:203 of aristolasicone (aristotelin- 19one) 11:314 of aristoteline 11:314 of artemisinin 5:24 of berberine 5:42,44 of bruceantin 5:39 of cadabicine methyl ether 5:210 of caratuberside A 5:212,213
183
of caratuberside B 5:213 of cedranolides 5:785 of cedrene 5:789 of colchicine 5:47-49 of cyanocycline A 10:106,107 of decitol 4:183 of dendropanoxide derivatives 2:102 of denticulatin 5:21,212 of eupatorenone 5:30 of flavone 5:14 of forsythiaside 5:509 of galactomannan 5:303 of ginamallene 5:369,370 of glucan 5:311 ofgualacm A 5:200 ofgualacln B 5:202 of gualanln A2 5:198 of gualanm B 5:199 of gualanln C 5:199 of gualanln E 5:199 ofheptitol 4:177 of holacanthone 5:39,40 of hortensin 5:15 of indicoside A 5:214 of indocoside B 5:215 of isoaquillochindiacetate 5:9 ofisobrucein A 5:39,40 of isopeduncularine 11:284 ofjuliflorinin 5:211 of L-arabinitol 4:181,182 of lareantin 5:10 of L-glycero-D-mannoheptose 4:219 of lycopene 7:342 of manzamine A 5:349-351 ofmanzamine B 5:349,350 ofmanzamine C 5:349,350 ofmanzamine F 5:351 of matairesinol 5:506 of nirurine 5:51 ofnortrachelogenin 5:531 of nortrachelogenin methyl ether 5:531 of odonticinin 5:209 of oligomers of L-glycero-Dmannohptose 4:219 ofonnamide A 5:365 of perezinone derivatives
5:74-78 of permethylated (meso)-pentitols 4:182 ofpicrasin B 5:39 of pinnatifidone 5:216,217 of pluchecinin 5:205 ofpolysaecharides 5:297,298 ofprionitin 5:31-32 of pullulan 5:288,289 of quinocarcin 10:118 of quinocarcinol 10:118 ofsaframycin A-D,F,G 10:82 of salvinolon 5:33-35 of sanguinarine 5:45 of saprorthoquinone 5:37 of staurosporine 5:61 of staurosporine aglycone 5:61 of suspensaside 5:509,510 ofzeaxanthin 7:342,345,346,351 of (x-chaparrinone 5:39,40 of (z-pipitzol 5:786,787 of [3-hydroxyacteoside 5:509 of [3-1umicolchicine 5:47-49 of x-lumicolchicine 5:47-49 CNS-activity 21:4 CNS-depressant activity 21:582 C-Nucleosides 10:337,338,355,358, 388-394 CoA ligas 25:653,666 Coagulation 26:240-245 role ofplatelet activating factor (PAF) 26:240-245 Co-artemether (lumefantrine/ benflumetol-artemether 26:783 Cobalamin 9:605,606 Cobalamin cofactor 11:210 Cobalt-stablized carbocations 3:83,84 in macrocyclization 3:83,84 coculolidene 3:456,488 synthesis of 3:477,478,488,489 Cobinamide 9:605,606 Cobyrininc acid 9:591,592,597-601, 603,605,606 Cocaethylene 22:7 (+)-Cocaine 22:7,19 (-)-Cocaine 22:7,19,722,723 Cocaine 13:631;21:84,488;26:820 as psychodelic drug 26:820
184
Cocarcinogen 1:547 Coccidiodomycosis 22:60 Coccidioides immitis 22:57 Coccidiomycosis 2:422 Coccinelline 6:447 from tetrahydropyridinium salts 6:447 Cocculus sermentosus 22:517 for epilepsy 22:517 for nocturnal epilepsy 22:517 Cocculus sp. 3:456,478 Cocculus trilobus 3:488 Cochineal 20:729,734,768-771 Cochliobolus lunatus 25:318 Cochliobolus miyabeanus 23:133; 26:460 Cochliophilin A 22:458,460,495 Cochlioquinone A 26:460 Cochlodinium polykrikoides 30:400,408 anti-influenza activity of 30:408 (R)Coclaurin 20:292 Coclaurine 24:887 effect as neuromuscular blocker 24:887 Codeine 13:631;18:47,74,87,91;21:52, 488;22:9,10,24 Codeine-6-glucuronide 22:10 Codeinone 22:10 Codium arabium 25:704 Codium dwarkense 25:725 Codium latum 26:1138 Codonocarpine 9:73 Codonopsis 13:660 Coelenterata 19:549;21:272 Coenenchyme 21:272 Coenzyme A 11:191 Coenzyme A thioester 11:197 coenzyme B ~2-dependent rearrangement 11:197 Coetsoidin A 15:137,145,154,171 Coetsoidin B 15:117,124,131,171 Coetsoidin C 15:137,145,154,171 Coetsoidin D 15:137,145,154,171 Coetsoidin E 15:137,145,154,171 Coetsoidin F 15:138,146,155,171 Coetsoidin G 15:138,146,155,171 Coffea arabica 29:578 Coffea sp. 21:502 Coffee bean 2:116
Coffein 20:6 (-)-trans-Cognac lactone 14:272,273 from levoglucosenone 14:272, 273 synthesis of 14:272,273 Cognitive functions 30:368 role of raphe nuclei in 30:368 Coix lachryma 27:193,212;29:599 Colaphellus loweringi 18:771 Colaptes auantus 5:836 11-epi-Colartin 7:213,232 Colchicine 3:287-299,5,179; 5:4649,798,799;12:179;21:98,109;22:8, 32,471 ;24:269;29:364,357 (-)-(aR,7,S)-colchicine as 29:357 (+)-(aR,7,S)-colchicine as 29:357 allocolchicinoid synthesis from 29:364 as antimitotic agents 29:357 as tubulin assembly inhibitor 29:357 discovery of 29:357 in gout treatment 29:357 NMR of 29:358 SAR of 29:357 X-ray structures cf 29:358 (7S)-Colchicine 3:287-299;13:652 Colchicum autumnale 5:46;25:473; 29:356,358 hepatop,.,tective effect of 25:472 serum ALT activity of 25.473 Colchicum kesselringii 29:356 Colchicum luteum 22:517 for epilepsy 22:517 Colchicum ritchii 29:358 Colchinol analogue 29:378 allocolchicinoids total synthesis of 29:378 Cold press extraction 21:574 Colebrookea oppositifolia 22:517 for epilepsy 22:517 Coleomycetes 9:203 Coleoptera 22:371;26:851 Coleosol 25:252 Colestane 25:49 Coleus amboinicus 22:517 Coleus aromaticus 22:517 for convulsive affections 22:517 for epileptic affections 22:517
185
Coleus forskohlii 19:137;25:252,256, 261,958 forskoline from 13:659 Coleus sativus 25:956 Coleus sp. 7:96,118 Coley's toxin 28:519 anti-tumor activity of 28:519 Collagen 30:594 platelet aggregation induced by 30:594 Collectotrichum coccodes 25:307 Collectotrichum lagenarium 16:302 Colletotrichum dematium 9:230,238, 239 Colletotrichum gloeosporiodes sp. Jussiaea 9:288,229,231-235, 238-241 Colletotrichum gloeosporioides sp. aeschynomene 9:230,238,239 Colletotrichum gloeosporioides (Glomerella cingulaa) 9:228,230, 232,238-240 Colletotrichum graminicola 9:230,238, 239 Colletotrichum heterostrophus 22:267 Colletotrichum lagenarium 12:400; 22:266 Colletotrichum lindemuthianum 9:230, 239 Colletotrichum malvalum 9:230,231, 238,239 Colletotrichum sp. 9:228,230,239,247 Collidine 6:385,396,399,400 S-Collidine 6:549,550 Collins allylic oxidation 6:27 in (-)-dictyolene synthesis 6:27 Collins oxidation 1:16,83,84,210,312, 313,315,316;6:16;11:83,84 ;19:320, 334,467 ;22:277 ;24:7 Collins reagent 6:115,350,317,335; 16:16;22:206,222 Collins-Wege intermediate 6:78,79 in (+)-sinularene synthesis 6:78,79 Collinusin 24:769,770 synthesis of 24:769,770 Collisella limatula 17:26 Collision activation 2:4 Collision induced fragmentation 2:43
Collisional activated decomposition spectrum (CAD) 5:634 Collisional activation (CA) spectra 5:633 Collision-induced decomposition (CID) 9:468,489,494,496 Collision-induced dissociation (CID) 18:195;19:643 Colneleic acid 9:569,570 COLOC 9:147,151,152,268,274,287, 515 COLOC spectrum 24:280 of casearin A 24:280 Colocynthis vulgaris 5:743,744,750 Colon 26 carcinoma 19:609 Colon cancer 23:293;30:5 clinical development for 30:5 chemotherapeutic agent for 30:5 Colon-38 tumor cells 25:761 Coloradocin 17:284,286,304-306 Colorectal carcinomas 30:762 in rat model 30:762 induction by 1,2-dimethylhydrazine (DMH) 30:762 use of Chlorella vulgaris for 30:762 Colorenone 21:285 Colorimetric assays 21:508,511,523, 551 Colourants 20:719-783 Colubrina asiatica 21:673 jujubogenin-3-O-glycosides from 21:673 Colubrinol 23:70 Columbamine 11:201-204,656;21:84 Columbianadin 23:363 Comantheria briareus 7:266 Comantheria perplexa 7:266;28:719 polyketide sulfates of 7:266 Comanthula pectinata 7:266 polyketide sulfates of 7:266 Comanthus parvicirrus 7:266 Comatula pectinata 28:719 anthraquinones from 28:719 Combined effects 27:438;28:562 of chitosan 28:562 of 5-fluorouracil 27:438 of 5-FU 28:562 Combretaceae 23:405;25:180
186
Combretastatin 22:471 Combretastatin A-4 24:406 antimitotic inhibitory activity of 24:406 as tubulin transferase 24:408,409 Combretum 25:180,183;26:1157 Combretum glutinosum 28:424 Combretum micranthum 28:424 Commiphora incisa 22:117 Commiphora molmol 24:119 Commiphora mukul 5:695,700,701 cis-Communic acid 28:456 trans-Communic acid 28:456 Comoramide A 25:883 Comoramide B 25:883 (+)-Compactin 11:335,336 biological activity of 11:335, 336 Compactin 22:251 Compactinervine 1:36 COMPARE 17:495 Competitive inhibitors 7:40,56,69,70 Comphor derivatives 4:628,632 synthesis from camphor- 10sulphonic acid 4:628,632 Comphor-2,8-homoenol 4:638,641,655 Complestatin 10:629,630,667 Complete freunds adjuvant (CFA) 19:702 Complex I inhibitor 28:436,437 annonaceous acetogenins as 28:437 capsaicin as 28:436,437 deguelin as 28:436 monotetrahydrofuranic derivatives 28:437 piericidin A as 28:436 rotenolone as 28:436 rotenone as 28:436 tephrosin as 28:436 Complex imidazole alkaloids 21:68 Complex indole alkaloids 21:79,84 Complex lipids 24:1015 Complexation reactions 21:508,511 Complex-built alkaloids 21:57 Complicatic acid 3:7,64 Complogenin 25:101,184,185,186,204 Comploside I 25:95 Comploside II 25:95,104,203
Comploside III 25:97 Comploside IV 25:97 Comploside V 25:97 Compositae plants 21:373,374;25:921; 30:732 as anti-inflammatory effect of 30:732 as antimicrobial agents 30:732 as antitumoral agents 30:732 as antiviral agents 30:732 biological activity of 30:732 medicinal value 30:732 pharmacological activity of 30:732 Computational molecular modeling 30:195 of AS-tetrahydrocannabinol 30:195 Computational studies 27:338 Compylotropis hirtella 25:93 COMT 21:17 Comutagenic effect 5:477 of estrogens 5:477 Con A 25:227,271,272,436,455,463, 464,477 Con A agarose 25:436 Con A hepatotoxicity 25:464 Con A induced liver injury 25:464,465 Con A model 25:463 Conangium odoratum 24:275 Concanavalin A 26:268,1135;30:4 in vitro 30:4 mitogenesis induction by 30:4 Concephalenol 2:213 ent-fl-epi-Concinndiol 25:249 Conculsive affections 22:511 Allium sativum L. for 22:511 Condensation 24:198 Condensation ofp-coumaroyl-CoA 25:655 Condensed tannins 29:572 effects on HIV- 1 protease 29:572 Conduritol B epoxide (1,2-anhydromyo-inositol) 7:37 c~-glucosidases inhibition by 7:37 [3-glucosidases inhibition by
187 7:37 chiro-inositol from 7:38 invertase binding with 7:38 Conduritol epoxides 7:37 Conduritols 14:179 Condyfolan-type Strychnos alkaloids 1:33 Condylocarpine 1:40,41,45 (+)-Condylocarpine 5:126 Condylocarpine-N4-oxide 5:125 Condylocarpine-type alkaloids 5:88,89 (+)-tubotaiwine 5:88,89 condylocarpine 5:88,89 condylocarpine-N4-oxide 5:89 tubotaiwine-N4-oxide 5:89 Condylomata acuminata 26:151 Conessine 26:837 Confertdiolide 29:90 activity in TPA assay system 29:90 activity in CRG assay system 29:90 activity in EPP assay system 29:90 Confertifolin 22:612 (+)-Confertifolin 4:405-407 (+)-euryfuran from 6:28 from 1-abietic acid 4:405-415 from D-podocarpic acid 4:405407 from Drimys species 4:404 from Drimys winteri Forst 4:418 from manool 4:424,425 in (-)-warburganal synthesis 4:418 synthesis of 4:405-419 1,2-syn-2,3-anti-Configuraiton 12:35,36,41,43,48 syn-Configuration 14:753 Configuration 5:704,706;27:471 of guggultetrol 5:704,706 of secondary hydroxy 27:471 arabino-Configuration 5:704 D[(R)]-Configuration 6:387 ofN-acetyl muramic acid 6:387 Conformational analysis 24:319,342 of astin B 24:342
Conformational control 11:152-158 in macrolactonization 11:152-158 Conformational effects 12:115 Conformational property 27:337 of analogs 27:336 Conformational studies 27:258-259 of (-)-cz-isoparteine 27:259 of (+)-[3-isosparteine 27:259 Conformations 27:335 ofabscisic acid 27:335,337 Conformers 27:340 ofabscisic acid 27:340 cisodial as 27:259 of sparteine 27:259 transoidal as 27:259 Confusameline 21:68 Congarosa 23:656 Congenital cytomegalovirus 30:374 autistic features in 30:374 Congo red 23:119 absorption maximum of 23:119 Congocidine 5:549 alkaline degradation 5:549 Congorinine E- 1 29:91 activity in TNFc~ assay system 29:91 (+)-[3-Conhydrine 13:483 Conicasterol 26:1176,1177 Conicasterone 26:1176,1177 (+)-Coniceine 16:466 ct-Conidendrin 20:108 from Taxus mariei 20:108 (-)-c~-Conidendrin 20:620 Conidia 9:228,230,233,238,240,241 Coniferae 7:99 Coniferaldehyde 5:471 (E)-Coniferaldehyde 5:472,475 Coniferin 5:471 Coniferyl alcohol 5:463,464,466,467, 471,472,475,495-497;25:2,666; 26:156,177 ;27:60,760 polymerization of 27:760 (E)-Coniferyl alcohol 5:472 (Z)-Coniferyl alcohol 5:472 Coniferyl aldehyde 27:763 (+)-Coniine 13:478 Coniine 21:51,97;25:528
188
Coniothyrium minitans 21:207 Coniothyrium palmarum 21:207 Coniothyrium spp. 21:207 Conium maculatum L. 22:517;25:528 for epilepsy 22:517 1,4-Conjugate addition 10:405,406 of electrophile 10:405,406 to a,[3-unsaturated carbocyclic aldimines 10:405,406 Conjugate addition 3:8;14:510;24:12, 188-190,744,747-749,775 Conjugated dienes 8:278 synthesis of 8:278 Conjugated forms 27:354 ofabscisic acid 27:354 Conjugated ketones 2:168 octant rule for 2:168 Conjugation-deconjugation epimerization 12:14 Connium 22:422 Conocarpan 26:202 Conocephalenol 9:249,252,255;18:625, 632 Conocephalum conicum 2:273,277, 278;9:249 Conoduramine 5:123;26:829 Conodurine 5:123;26:829 Con-O-methylnogarol 4:318,357 7Conopeum seuratum 17:79 Conopharyngine 5:128 Conopharyngine (10,11-dimethoxycoronaridine) 9:174,176,177 Conopharyngine hydroxyindolenine 5:128,195 Conopharyngine oxindole 5:128 Conopharyngine pseudoindoxyl 5:128,129 a-Conotoxin 21:52 c0-Conotoxin GVIA 18:722 p-Conotoxins 21:73 Conservula cinisigna 26:698 Consolida 26:868 Consolida orientalis 27:188,191 Constipation 30:194 as opioid's side effect 30:194 Constitutional isomers 27:362 of myrcene 27:363
of ocymene 27:363 structure of 27:363 Contact dermatitis 30:168-169 phenolic lipids role in 30:168169 Contents 27:413,416 of tannins 27:413,416 Conthium guiinzii 22:515 Contotoxins 21:79 Contraction 24:910-913 effect of cholecystokinin 24:910-913 Controlled crisscross annulation 13:442 Conus 25:732 Conus radiatus 21:320 Convergent lactone synthon 13:604 synthesis of 13:604 Conversion 22:135 of cortisone to cortisol 22:135 Conversion of MFA 28:333 to (+)-paraherquamide B 28:333 Conversion of PHB 28:331,335,331, 367367 to paraherquamide A 28:331,367 Convolvulanic acid A and B 15:342 Convolvulol 15:342 Convolvulus arvensis L. 15:341 ;22:518 Convolvulus pluricaulis 22:518 Convorvolus microphyllus 13:312 Convulsions 22:510-536,471,559,580, 582,633,742 Aconitumjaponicum Thunb. for 22:510 Acorus calamus L. in 22:510 Aeolanthus suaveolens in 22:511 Aglaia odorata Lour. in 22:511 Allopylus africanus Beouv. for 22:511 Aloe vera L. for 22:511 Arisaema amurense Maxim for 22:512,513 Arisaema consanguineum for 22:512 Artocarpus helerophyllus for 22:513 Caesalpinia bonduc L. for 22:514 Caesalpinia pulcherrima L. for 22:514,471
189
Canthium bibracteatum for 22:515
Casimiroa edulis for 22:515 Cassia occidentalis for 22:580, 582
Catunaregam nilotica for 22:516 Celtis cinnamomea for 22:516 Curcuma aromatica for 22:518 Deinbollia borbonica for 22:519 Desmodium polycarpum DC. for 22:519
Desmodium triflorum DC. for 22:519
Euphorbia hirta L. for 22:520 Ferulafoetida for 22:521 Ficus capensis for 22:521 Gentiana crassicaulis for 22:521 Gentiana dahurica for 22:521 Gentiana decumbens L. for 22:521
Gentiana dehurica for 22:521 Gentiana fetisowii Regel for 22:521
Gentiana macrophylla for 22:521
Gentiana tibetica King for 22:521
Gentiana wutaiensis for 22:522 Gynandropsis pentaphylla for 22:522
Hedeoma pulegioides L. for 22:522
Hoslundia opposita for 22:523 Hoya austrulis R. for 22:523 Jatropha curcas R. for 22:524 Ledebouriella seseloides for 22:524
Leucas lavandulifolia for 22:525 Lobelia inflata L. for 22:525 Mellittia usaramensis for 22:526 Micromelum compressum for 22:526
Myrica salicifolia for 22:527 Nicotiana tobacum L. for 22:527 Paeonia emodi for 22:527,528 Paeonia officinalis L. for 22:528 Paeonia suffruticosa for 22:528 Palisota ambigua for 22:528 Panax quinquefolius L. for
22:528
Phylanthus emblicata L. for 22:529
Polygonum japonicum for 22:530,633
Pothos scandens L. for 22:530 Psychotria curviflora for 22:530 Randia esculenta for 22:530 Ruta chalespensis for 22:531 Ruta graveolens L. for 22:531 Scopaliajaponica for 22:531, 742
Securidoca longepedunculata for 22:532
Solanum carolinense L. for 22:532
Tetrameles nudiflora for 22:533 use of arnica in 22:559 use of Artocarpus heterophyllus in 22:513 use of Basilicum polystachyon in 22:514 Veratrum nigrum L. for 22:534 Xylotheca tettensis var. fissistyla for 22:535 Zanthoxylum holtzianum for 22:535 Zingiber ottensi for 22:536 Convulsions, in children 22:514-516, 524,527,529,530,532,534,535,580, 582 Caesalpinia pulcherrima L. for 22:514 Canthium bibracteatum for 22:515 Casimiroa edulis for 22:515 Cassia occidentalis for 22:580, 582 Catunaregam nilotica for 22:516 Khaya ivorensis A. for 22:524 Khaya senegalensis A. for 22:524 Newbouldia leavis for 22:527 Phyllanthus urinaria L. for 22:529 Phyllostachys nigra Lodd for 22:529 Psidium guyava L. for 22:530 Spilanthes mauritiana for 22:532
190
Uncaria rhyncophylla as 22:534 Vernonia chinensis for 22:535 Vernonia hildehrandtii for 22:535 Vitex negundo for 22:535 Ximenia americana L. for 22:535 Convulsions, in infants 22:519 Desmodium pulchellum for 22:519 Convulsive affections 22:517,527 Coleus aromaticus for 22:517 Nardostachys jatamansi DC. for 22:527 Convulsive cough 22:517 Citrus maxima for 22:517 Convulsive disorders, of children 22:534 Thuja orientalis L. for 22:534 Conyza dioscoridis 28:425 Conyza filaginoides 29:586 Conyza odentophylla (Pluchea arguta) 9:65-68 sesquiterpenes from 9:65-68 Conyza steudellii 25:25 Conyza trihecatactis 25:252 Cook 29:375 allocolchicinoids total synthesis by 29:375 Cooked garlic 23:464 chemistry of 23:464 Cooke's dianion 13:594 Coomassie 9:453 Cooperia curticei 26:490 Cooxidants 19:270 (+)-Copacamphor 4:675 Copaene 8:33-36;17:608;23:535 c~-Copaene 8:33-36 Copaifera L. 25:168 Copaifera riticulata 22:360 Copalliferol A 23:533;26:561,563 Copalliferol B 23:533;26:561,563 Cope elimination 3:468,470,471,494, 110 Cope reaction 13:109 Cope rearrangement 1:182,236,416, 566,567 ;3:47,98,139,190,191,249, 372;7:216;10:236 Cope ring enlargement 12:193
Copitisine 21:84 Copper (I) catalyzed Grignard additions 10:180 Copper (I) trifluoromethane-sulfonate benzene complex 1:271,272 Copper acetylide 4:396,398 Copper amine oxidases 26:1262,1271, 1272,1275,1283 Copper catalyzed Grignard reaction 11:81,82 Coprinus mcrorhizus var. micro~porus 5:288 Coprotoxins 18:698 Copsychus saularis 5:837 hemoglobin components of 5:837 Coptisjaponica var. dissecta 26:268 Coptisine 14:793-795 conversion to ochrobirine and corydaine 1:289-291 (+)-chelamine from 14:793-795 (+)-chelidonine from 14:793-795 sanguinarine from 14:793-795 Cora islandica 5:313 Cora pavonia 5:313 Cora silandica 5:128 Coracias benghulensis 5:837 hemoglobin components of 5:837 Coracina novachollandiae 5:837 hemoglobin components of 5:837 Corallan 23:163 Corallistes fulvodesmus 25:829; 26:1213;28:688 Corallistes sp. 26:1214 Corallistes undulatus 26:1214 Corallistine 25:829,830;28:688 X-ray crystallography of 28:688 Corallistins A-E 26:1213,1214 Corallydictyals A and B 27:855,856 Corals 18:716 Corbicula sandai 26:1123 Corchorus acutangulus 18:650; 23:487,511 23-hydroxylongispinogenin from 18:650 3[3,1613,23,28-tetrahydroxyolean-
191 12-ene from 18:650 saponins of 23:511 Corchorusins 23:487 Corchorusin A 23:512 Corchorusin B 23:512 Corchorusin C 23:512 Corchorusin C~ 23:512 Corchorusin D 23:512 Corchorusin D I 23:512 Corchorusin D2 23:512 Corchorusin D3 23:512 Corculigo 25:180 Cordia goetzei 7:408,409;23:342 Cordiceps ophioglossoides 5:279,318, 320 Cordiceps sinensis 5:279 Cordigol 7:408,409;23:342 Cordigone 7:408,409;23:342 Cordoa piaca 29:777 Cordycepin 10:357,358 from 3-deoxy-2,5-di-O-(p-nitro-
benzo yl )-f3-D-erythropentosyl bromide 10:357,358 synthesis of 10:357,358 Cordycepin (3'-deoxyadenosine) 10:593 from adenosine 10:593 Cordyceps cicadea 23:115,134 Cordyceps ophioglossoides 23:133 Coreopsis parvifolia 5:800 Corepoxylone 18:195 Corey asymmetric osmylation 26:1232 Corey epoxide 13:568 Corey method 11:154,157 Corey procedure 6:562 Corey reagent 14:268;19:452 Corey's oxazaborolidine catalysts 18:182 Corey-Fuchs protocol 30:43 Corey-Kim oxidation 12:338 Corey-Mukaiyama method 1:271 Corey-Myers synthesis 6:195 Corey-Nicolaou method 12:52,53 Corey's lactone 7:480-482 Coriandrum sativum 27:376 Coriariajaponica 23:404 Coriaria nepalensis 13:311 Coriariaceae 23:404 Coriariin A 23:402 Coriariin D 23:404
Coriariin E 23:404 Coridin display activity 22:202 Corilagin (hydrolysable tannin) 29:572 effects on HIV-1 protease 29:572 Corilous versicolor 452 (S)-Coriolic acid 13:311 Coriolic acid 26:461 Coriolin B 3:7,65 Coriolins 13:6 Coriolus sanguineus 26:1012 Corlumine 21:69 Corn earworm 24:865 bioassay of 24:865 Corn Hageman Factor Inhibitor (CHFI) 29:602 effects on cz-amylase 29:601 effects on ~x-amylase inhibitor 29:602 effects on cereal ~ amylase/ trypsin inhibitor family homologue 29:601 effects on cereal s-amylase 29:602 effects on Factor XIIa 29:602 effects on CM homologues 29:601 effects on trypsin inhibitor homologue 29:602 inhibitor proteins 29:601 RA5 as 29:601 RBI (Ragi bifunctional I) as 29:601 rice allergenic protein as 29:601 SIc~4 as 29:601 Corn syrup 2:355 Cornaceae 23:405 Cornforth's methodology 30:434 Cornitermes ovatus 15:384 Cornitermes pugnax 15:384 Cornoside 16:616 Cornus florida 7:427 Cornus officinalis 23:405 Cornusiin A 23:405 Cornusiin C 23:405,409 Coronaridin 5:127,171 ;25:533;28:234 as immunosuppressive drug 25:533
192 sesterterpenes halisulfate- 1 from 28:672 suvanine from 28:672 Coronaridine hydroxyindolenine 5:127 Coronaridine-type alkaloids 5:93-101 (-)-heyneanine 5:98 (-)-ibogamine 5:93,97 (+)-heyneanine 5:94 (+)-ibogamine 5:97 10-hydroxycoronaridine 5:98 10-hydroxyheyneanine 5:99 11-hydroxycoronaridine 5:98 11-hydroxyheyneanine 5:99 18-hydroxycoronaridine 5:98 18-hydroxyvoacangine 5:1 O0 19-epi-heyneanine 5:98 19-epi-iboxygaine R 5:97 19-epi-iboxygaline 19(R) 5:98 19-epi-voacfistine 5:100 19-oxo-voacangine 5:99 19R-hydroxyconopharyngine 5:101 19S-3,19-oxidovoacangine 5:99 19S-hydroxyconopharyngine 5:101 19S-iboxygaine 5:97 3-(2-oxopropyl-)-coronaridine 5:100 3,19 R-oxide-coronaridine 5:94,98 3-/R/S-hydroxyconopharyngine hydroxyindolenine 5:101 3-cyano-voacangine 5:100 3-ethoxy coronaridine 5:99 3-hydroxycoronaridine 5:98 3-hydroxymethylvoacangine 5:100 3-hydroxyvoacangine 5:100 3-ketopropyl- 19R-heyneanine 5:100 3-oxo-conopharyngine 5:100 3-oxo-coronaridine 5:97 3-oxo-coronaridine hydroxyindolenine 5:99 3-oxo-heyneanine 5:99 3-oxo-voacangine 5:99 3-oxo-voacristine 5:100
3R/S-hydroxyconpharyngine 5:101
3R-hydroxy- 19R-heyneanine 5:94 3-R-hydroxyconopharyngine hydroxyindolenine 5:101 3-R-hydroxyisovoacangine 5:99 3S-3 [3-hydroxyethylcoronaridine 5:99 3S-hydroxy- 19R-heyneanine 5:94 3S-hydroxyvoacangine 5:100 5-oxo-coronaridine 5:98 6-oxo-coronaridine 5:98 6R-3,6-oxidovoacangine Naoxide 5:100 catharanthine 5:97 conopharyngine 5:100 conopharyngine hydroxyindolenine 5:101 coronaridine 5:97 coronaridine hydroxyindolenine 5:98 ibogaine 5:97 ibogaine hydroxyindolenine 5:97 iboxygaine hydroxyindolenine 5:97 isovoacangine 5:99 isovoacristine 5:100 tabernanthine 5:97 voacangine 5:99 voacangine hydroxyindolenine 5:100 voacristine 5:100 voacristine hydroxyindolenine 5:100 Coronarin A 23:838 Coronarin B 23:838 Coronarin E 23:809 Coronarins (A-D) 25:265,266 Coronary artery ligation-reperfusion 25:594 Coronary heart disease 24:376-381, 30:55,72 Angelica keiskei use in 30:72 role of cholesterol oxides 24:351-398 role of natural products in 30:55 Coronatine 4:690 Coronavirus A-59 21:393 Coronilla 27:519
193
Coronopifolia 25:771 Corosolic acid 27:861,862 Corossolin 26:441,442 Corphinoids 9:592 Corphins 9:597,605 Corpora allata 22:377 Corpora cardiaca 2:90,93,94,99,106, 112;9:487,490 Corriander oil 25:140 Cortex eucommia 20:646 Cortical abnormalities 30:378 Corticium caeruleum 18:712 Corticium rolfsii 21:196 A 9(1 lLCorticoids 9:426,427 Corticomimetic activity 21:657 Corticosteroids 22:134 Corticosterone 22:135 Corticum sp. 25:707 Cortinarius odorifer 22:580 Cortinarius sp. 22:556,579 Cortisone 22:135;25:516 conversion to cortisol 22:135 Corvacrol 21:598,601 Corvularia eragrostidis 29:475 Corvus splendens 5:837 (+)-Corydalic acid methyl ester 14:796799 biosynthesis of 14:796 from corysamine 14:796-799 from tetrahydrocorysamine 14:796 synthesis of 14:796-799 via hypothetical enamine 14:796 Corydalis caucasica DC. 27:163 Corydalis decumbens 21:733 Corydalis flabellata 27:169 Corydalis rutifolia 27:170 Corydalis severtzowii RgI. 27:163 Corydalis sp. 22:518 Corydalisol 6:494 from protopine N-oxide 6:494 Corydamine 4:547 Corylus 26:894,905 Corymbellus aureus 6:135 Corymbiu villosum 25:251 Corynan-17-oic acid methyl ester 14:722-724
(+)-Z-geissoschizol from 14:722724 (+)-3-epi-Z-geissoschizol from 14:722-724 using trimethyl orthoacetate 14:725 stereoselective 14:725 using dimethyl acetamide dimethyl acetal 14:722724 Corynane-strychnane series 6:503,520 Corynanthe yohimbe K. 26:143 Corynantheyohimbe alkaloids 8:283 ajmalicine 8:283 yohimbine 8:283 (+)-Corynantheal 18:332 Corynanthean 5:112,113 Corynanthean-type alkaloids 5:71,150163 Corynantheidol 25:24 Corynantheine-type indole alkaloids 25:31 Corynantheine-type oxindole alkaloids 25:26 Corynanthe-type alkaloids 15:378 Corynanthine 21:57 Coryne cassiicola 25:149 Corynebacteirum kutschei 25:452 Corynebacteirum sp. 25:145 Corynebacteriurn bovis 12:400 Corynebacterium fescians 26:618 Corynebacterium glutammicum 13:320 Corynebacteriurn parvum 23:134 Corynebacterium poinsettiae 7:357; 20:594 Corynespora cassiicola 25:149,162,166 Corynine 22:25 Corynocarpin 27:522 Corynoline 14:770 (+)-Corynoline 14:785-787 from corysamine 14:785-787 oxidation of 14:788,789 synthesis of 14:785-787 through enamine-aldehyde cyclization 14:785-788 Corynoline-type alkaloids 4:455 Corynoxine 25:27 Corynoxine B 25:27
194
Corysamine 14:796-799 (+)-corydalic acid methyl ester from 14:796-799 (+)-corynoline from 14:785-787 (+)-isocorynoline from 14:785787 (+)- 11-epicorynoline from 14:785-787 (+)- 11-epiisocorynoline from 14:785-787 Corythuca 26:443 Corytuberine 18:58 (+)-Corytuberine 30:563,589 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:589 Cosciansterias tenuispina 7:298; 15:46,51,52 cosicinasteroside D from 7:298 Coscinasteroside A-C 15:53 Coscinasteroside D 7:298,302,53 Coscinasteroside E-F 15:53 Coscinoderma mathewsi 25:699;28:672 as protein phosphatase inhibitor 28:672 Coscinoderma sp. 28:670 Cosculine 26:824,826 (+)-Costaclavine 18:336 Costaricensis 26:484 Costasiella ocellifera 25:787 Costaticella hasta 17:90;18:726;21:260 harman from 18:726 pavettine from 18:726 3-Costoyloxydehydroleucodin 29:90 activity in NFkB assay system 29:90 Costunolide 7:230;20:471,472; 24:848 ;27:559;29:89 activity in AM assay system 29:89 activity in Colon-1 assay system 29:89 activity in iNOS assay system 29:89 activity in NFkB assay system 29:89
activity in ODC assay system 29:89 activity in RAS assay system 29:89 carcinoma 24:848 topoisomerase inhibitory activity 24:848 Costus speciosus 23:821 1H-Ill-COSY 21:692,732 IH-13C-COSY 21:692 ill-COSY 21:764 COSY 26:16,29,34,37,41 ofbisdesmoside 26:41 ofdianchinenoside E 26:34 of dianchinenoside F 26:37 ofvaccaroside D 26:29 2D-COSY spectrum 21:143 Cosynthetase 9:596 Cotinine 21:51;22:12 Cotinine N-oxide 22:12 Cotonefuran 23:341 Cotoneuster lactea 23:341 Cotton curve 6:542 Cotton effect 2:140,160,161,169,170, 172,173,255,286, 434,435,551,623; 19:259 Cotton pellet granuloma 25:46 inhibition of 25:46 Cottonogenic derivatives 2:166 Cotyledon bioassay 26:583 Coughing spasm 22:525 Leucas tavandulifolia for 22:525 Coulomb interactions 2:165 Coulomb's law 2:164,173 4-Coumarate 25:653,664 4-Coumarate 3-hydroxylase 5:468,469 1,4-Coumarate:CoA ligase 5:470 Coumaric acid 9:279;25:657;30:730 structure of 30:730 4-Coumaric acid 25:652,660 m-Coumaric acid 25:923,925 p-Coumaric acid 23:537,744,745,551, 825 ;25:655,657,920,925,936;28:262 in cereals brans 28:262 in spinach 28:262 in sugar beet fibre 28:262 cis-Coumaric acid 29:101 activity in CRG bioassay system 29:101
195 (E)-4-Coumaric acid 5:467,469,470 m-Coumaric acid glucuronide 25:923, 925 Coumarine isoepoxypteryxin 25:476 Coumarin-hemiterpene ethers 7:205 Coumarinolignan derivatives 5:9 Coumarinolignan isomer 5:5,6 Coumarinolignans 5:3,5,8,9,495,496 Coumarins 4:3,5,8,9,202,204-206,220, 224,225,367,372,375,377,389,391, 399,400,495,496,505,517-521, 574-575,971-1080;9:113-116,529; 20:283,497 ;22:75 ;23:356; 24:499-503 ;25:472;30:729 as antiviral compound 24:499-503 as trans-O-glucosylcinnamic acid 30:729 derivatives of benzo-~-pyrone 30:729 hepatoprotective mechanism of 25:472 structure of 30:729 Coumarin-sesquiterpene ethers 7:269 in Artemisia abrotanum 7:269 Coumarouna odorata 23:337 [3-O-cis-p-coumaroyl alphitolic acid 28:623 anti-microbial activity of 28:62 [3-O-trans-p-coumaroyl alphitolic acid 28:623 anti-microbial activity of 28:62 Coumaroyl CoA Chymo trypsins 25:388 [3-O-cis-p-coumaroyl maslinic acid 28:623 anti-microbial activity of 28:62 p-Coumaroyl tyramine 22:631 p-Coumaroyl-meso-tartaric acid 23:764 11-O-p-Coumaroylnepecticyn 27:477 structure of 27:477 3-O-Coumaroylquinic acid 25:920 4-O-Coumaroylquinic acid 25:920 5-O-Coumaroylquinic acid 25:920 p-Coumaroylquinic acids 28:262 in sweet cherries 28:262 p-Coumaryl alcohol 27:760 polymerization of 27:760
4-Coumaryl alcohol 5:463,467 trans-p-Coumaryl diacetate 23:801 Coumaryl glycosides 25:543 vanicoside A 25:543 vanicoside B 25:543 p-Coumaryl-CoA 25:652;27:768 p-Coumaryl-hydroxy oxyagmatine 27:765 peroxidase-catalyzed dimerization of 27:765 p-Coumaryl-hydroxyagmatine 27:765 peroxidase-catalyzed dimerization of 27:765 Coumermycin A 1 23:357 Coumestrans 27:894 Coumestrol 26:472 3~-O-cis-Coumroylmonogynol A 20:704 from Salvia montbretii 20:704 3~-O-trans-p-Coumroylmonogynol A 20:704 from Salvia montbretii 20:704 Counter-current chromatography (CCC) 25:205 IH-15N Coupling 26:1047 as structural probe 26:1047 Coupling constants 6:128,129 of 18-epi-dialdehydes 6:128,129 Coupling reactions 26:113,114,119 of secologanin 26:113,114,119 Covalent interactions 26:995-1001 of HA with 26:995-1001 Cowania mexicana 24:249 ' Cowaxanthone 26:805,806 Cowdria ruminantium 28:394 as rickettsial pathogens 28:394 COX enzymes 29:672 expression of 29:672 in hormonal production 29:672 in platelet aggregation 29:672 in prostacyclin production 29:672 in wound healing 29:672 inhibitors of 29:673 mechanism of action of 29:673 role in Alzheimer's disease (AD) 29:673 role in kidney function 29:672
196
role in pregnancy 29:672 role in stomach 29:672 COX inhibitor 29:673 ;30:192 allergic attacks-promotion by 29:674 aspirin as 30:192 aspirin-induced asthma (AIA) syndrome by 29:675 assay for 29:677 asthmatic attacks-promotion by 29:674 baicalin as 29:680 cell line based assay for 29:677 enzyme immunoassay (EIA) for 29:677 for familial adenomatous polyposis 29:674 ibuprofen as 30:192 in AD pathogenesis 29:673 in bladder tumor 29:673 in breast tumor 29:673 in cancer treatment 29:673 in cerebrovascular diseases 29:674 in osteoarthritis 29:673 in rheumatoid arthritis 29:673 in skin treatment 29:673 indomethacin as 30:192 naproxen as 29:673 radioimmunoassay for 29:677 rofeCOXib as 29:673 role in broken bone growth 29:674 role in congestive heart failure 29:674 role in exacerbate coronary disease 29:674 role in immune system 29:674 role in renal failure 29:674 role in ulcer healing 29:674 scintillation proximity assay for 29:677 to alleviate symptoms 29:673 to treat pain 29:673 to treat swelling 29:673 toxicity of 29:674 up-regulation of 29:673 wogonin as 29:680
COX/LOX dual inhibitors 29:671,675 as anti-inflammatory agents 29:671 assays for 29:676 cardio-protective functions of 29:676 fromAcacia catechu 29:678 from Scutellaria baicalensis Georgi. (Lamiaceae) 29:678 from Scutellaria lateriflora L. 29:678 natural type of 29:671 nonsteroidal anti-inflammatory drugs (NSAIDs) as 29:672 prostaglandins suppression by 29:676 role in angiotensin II-induced contractions 29:675 role in coronary vasoconstriction 29:675 role in lens protein-induced occular inflammation 29:675 therapeutical benefits of 29:675 COX/LOX natural dual inhibitors 29:681 3 -( 4 '-aceto xy-3 ', 5 '-dime th yl) benzylidene- 1,2-dihydropyrrolo [2,1-[3]quinazoline-9-one as 29:693 acetylenes as 29:682 aethiopinone as 29:688,691 alcohols as 29:681 aliphatic sulfides as 29:684 alkaloids as 29:692 alkamides as 29:683 artonon E as 29:706 atractylochromene as 29:695 aucubin as 29:686 bornyl ferulate as 29:696 ~-boswelic acid 29:692 buddledin A as 29:687 6-(3-carboxybut-2-enyl)-7hydroxy-coumarin as 29:699 catechins as 29:708 centaureidin as 29:704 chalcones as 29:707 chlorogenic acid as 29:697 cis-hexadec- 11-en-7,9-diynote acid as 29:683
197 coumarins as 29:699,700 crysins as 29:702 curcumin as 29:695 daphnetin as 29:699 6-demethyl-vignafuran as 29:709 (2,3-dihydro- 1H-pyrrolizin-5-yl) acetic acid as 29:693 5,3 '- dihydroxy-4 '-methoxy- 7carbomethoxyflavonol as 29:704 11,12-dihydroxy-6-oxo-8,11,13abietatriene as 29:688 11 (S), 16(R)-dihydroxy-octadeca9Z, 17-diene- 12,14-diyn- 1-yl acetate as 29:682 diterpenes as 29:687
dodeca-2E,4E,8Z, 10E/Ztetraenoic acid isobutylamide as 29:684 E-isolinaridial as 29:690 E-isolinaridial methylketoine as 29:690 epigalloactechin-3-gallate (EGCG) as 29:708 falcarindiol as 29:682 fatty acids as 29:681 fisetin as 29:704 flavones as 29:702 flavonoids as 29:700 flavonols as 29:704 from Aaronsohnia 29:683 from Achillea 29:683 from Allium sativum L. 29:684 fromAllium ursinum 29:684 from Anacyclus 29:683 from Angelica pubescens F. Biserrata (Apiaceae) 29:699 from Artocarpus communis 29:706 from Asteraceae 29:703 from Atractylodes lancea 29:694 fromAtuna racemosa 29:708 from Bidens campyltheca Schultz 29:682 from Boswellia serrata Roxb. (Burseraceae) 29:691 from Buddleja globosa Hope (Buddlejaceae) 29:686 from Callna vulgaris 29:691
from Ceiba pentandra 29:708 from Celastrus orbiculatus 29:708 from Chymacyparis taiwanesis 29:698 from Curcuma longa 29:695 from Echinacea angustifolia 29:684 fromEchinacea species 29:683 from Euniceafusca 29:690 from Helichrysum picardii 29:702 from Ircinia spinosula 29:694 from Linaria saxatilis var. glutinosa 29:689 from Macfadyena unguis-cati 29:696 from Morus mongolica 29:705 from Nigella satvia L. (ranunculaceae) 29:694 from Notopterygium incisum T. 29:696 from Peucedanum ostruthium (L.) 29:699 from Phillyrea latifolia L. 29:685 from Piper sarmentosum Roxb. 29:684 from Pseudopterogorgia elizabethae 29:689 from Psoralea corylifolia L. 29:705 from Punica granatum, L. Punicaceae 29:701 from Salvia aethiopis L. (Labiatae) 29:690 from Salvia athiopis (Labiatae) 29:687 from Saposhnikovia divaricata 29:682 from Scrophularia scorodonia L. 29:685 from Sideritis angustifolia 29:687 from Sideritis mugronensis 29:701 from Sophora flavescense 29:705 from Syzygium carynocarpum
198 29:708 from Syzygium malaccense 29:708 from Tanacetum microphyllum 29:703 from Tanacetum parthenium (L.) 29:686,703 from Tanacetum vulgare 29:703 from Teucrium species 29:687 from Urtica dioica L. (Urticaceae) 29:697 from Vantanea peruviana 29:708 from Zanthoxylum chalybeum Engl. 29:692 fuscoside B as 29:691 gnaphalin as 29:704 gossypetin as 29:704 gossypin as 29:704 gossypol as 29:697 harpagosides as 29:686 6-hydro xy-2-(2 hydroxy-4methoxyphenyl)benzo furan as 29:709 3-hydroxy-flavone as 29:704 hypolaetin as 29:702 hypolaetin-8-glucoside as 29:702 iridoids as 29:685 kaempferol as 29:704 kenusanone C as 29:705 kurarinone as 29:705 kuwanon C as 29:702 lagascatriol as 29:688 linoleic acid as 29:682 medicarpin as 29:709 6-methoxy luteolin as 29:702 6-methoxy luteolin-3'-methyl ether as 29:702 6-methoxy-kaempferol-3,4'dimethyl ether as 29:704 methyl 1-propenyl disulfide 5oxide as 29:685 O-methyl-pseudopterosine as 29:689 5-methyl-sophoraflavanone B as 29:705 morin as 29:704 morusin as 29:702 myricetin as 29:704
naphthol as 29:698 naringenin as 29:705 naringin as 29:705 oleic acid as 29:682 palmitic acid as 29:682 parthenolide as 29:687 pentadeca-6,8, lO-triynoic acid as 29:683 phenethyl ferulate as 29:696 phenolic compounds as 29:695 1-propenyl 1-(1-propenyl sulfinyl) propyl disulfide as 29:685 psoralidin as 29:706 quercetagetin 3,6,3'-trimethyl ether as 29:704 quercetin as 29:704 6-(2-quinolinymethoxy)etodolac as 29:693 quinones as 29:694 rutin as 29:704 safynol-2-O-isobutyrate as 29:683 sangenon D as 29:706 sanggenon B as 29:706 sesquiterpenes as 29:686 sophoraflavanone D as 29:705 sophoraflavonone G as 29:705 tanaparthin-ct-peroxide as 29:687 teucrin A as 29:688 thymoquinone as 29:695 triterpenoids as 29:691 tropolone as 29:698 ursolic acid as 29:692 COX- 1 enzyme 30:192 in kidney 30:192 in stomach 30:192 physiological effects of 30:192 role in nflammation 30:192 COX-2 enzyme 30:192 inflammation induction by 30:192 COX-2 gene expression 30:319 in RAW2647 macrophages 30:319 COX-2 inhibitors 30:192 celecoxib as 30:192 in treatment of inflammatory
199 disorders 30:192 in treatment of pain disorders 30:192 rofecoxib as 30:192 COX-3 enzyme 30:192 in brain 30:192 ~SC-oxepane 10:212,213 synthesis of 10:212,213 Coxiella burnetii 28:394 in cattle 28:394 in sheep 28:394 Coxsackievirus 30:412 Aloe barbadensis against 30:412 Coyotillo 22:558 CP-263114 24:434,435 weak inhibitor of 24:435 Cp2ZrC12. AgC104 10:370 aryl C-glycosides from 10:370 CPH82 26:170 for treatment of rheumatoid arthritis 26:170 ~SC-phytosphingosine 18:485,486 enantioselective synthesis of 18:485,486 CPI-CDPI2 3:362,367-370 CPMAS spectra 5:776 of 6-hydroxyperezone 5:776 C-prostaglandins 16:367-368 synthesis of 16:367-368 CPT activity 21:458 CPT-11 20:458 C-pyranosides 10:340 synthesis of 10:340 Cram (1,2-syn) coupling product 12:42, 43,45,48,50,55 Cram ( 1,2-syn)-selective coupling reaction 12:35,36 ofchiralvinyl halide 12:35,36 with A chiral-(x-methylsubstituted aldehyde 12:35,36 Cram addition 16:345 of enolates 16:345 of 2-1ithiofurans 16:346 Cram rule selectivity 1:608 Cram selectivity 19:473 Cram's rule 14:482;16:350 Cram's chelation model 19:320,482 Cram's product 19:471,476 Crambescidine 21:79
Crambesescidin 22:35 Cramer reaction 8:77,80 Cram's cyclic model 4:201,491 of 1,2-asymmetric induction 4:201 Cram-selective aldol-lactonization 14:115 Crassin 8:15,19-30 antitumor activity of 8:15,19 titanium-induced coupling 8:19-30 (+)-Crassin 8:29,30 Crassin acetate 8:15,20 antibiotic activity of 8:15 ~H-NMR spectrum of 8:20 mass spectrometry of 8:20 X-ray analysis of 8:20 synthesis of 10:6,7 Crassin alcohol 10:7 Crataegus monogyna 21:502;22:118; 29:579 Crataegus pinnatifida 27:861 ;29:588 Crataegus sinaica 21:507 Crataegus sp. 21:535 Crataeva nurvala 5:209 Creatine kinase (CK) 25:527;30:837, 844 hydrolysis by F-II 30:837 Crebanine 21:57 Crella sp. 25:704;28:706,707 crellastanin A from 28:706 crellastatins B-M from 28:707 Crella spinulata 25:832;28:708 benzylthiocrellidone from 28:708 dimedone unit of 28:708 Crellastatin 25:704 Crematogaster deformis 15:383 Crematogaster lineolata 6:454 Crematogaster scutellaris 6:422,453, 455 Crenomytilus grayanus 30:408 anti-influenza activity of 30:408 Crepidamine 12:277,285 Crepidine 12:285,287 from Dendrobium crepidatum 12:285 X-ray diffraction studies of 12:285
200
Crescentia cujeta 20:494 furanoaphthoquinones from 20:494 p-Cresyl methyl ether 6:83,84 Birch reduction of 6:83,84 (+)-9-pupukanone synthesis from 6:83,84 Creulide 25:690 Cribochalina sp. 25:900 Cribraria intricata 29:256 fruit bodies of 29:256 Cribraria purpurea 29:258 antimicrobial activity of 29:258 crude extract of 29:258 Cribricellina cribraria 17:79,8990;21:260;25:819;28:619 [3-carboline alkaloid from 28:619 carboline from 28:619 1 -ethyl-4-methyl-sulfone- ~antimicrobial activity of 28:619 Cribrocalina vasculum 9:37 dihydrocalysterol from 9:37 petrosterol from 9:37 Criegee rearrangement 14:128 Crimean-Congo haemorrhagic fever virus (CCHFV) 30:412 Crimmins synthesis 12:11,12 Crinine 20:325,20:351,20:369,20:384 Crinitol 20:25 from Cystoseira crinita 20:25 from marine algae 20:25-37 from Sargassum tortile 20:26,20:27 Crinoidea 7:266,100-103 Crinosterol 16:322,332,334 Crinum americanum 26:616 Crinum asiaticum 18:687 Crinum oliganthum 20:234 mesembrenol from 20:234 Criptococcus neoformans ATCC 90112 28:476 Crisophanol 30:306 structure 30:306 Crispolide 27:560 Cristacarpin 20:496,20:497 Cristaria plicata 25:868
Crithidia deanei 2:296-298 polysaccharides in 2:296-298 Crithidia fasciculata 2:295-297,577 Crithidia guilhermei 18:791,792 Crithidia harmosa 2:298 Crithidia luciliae 2:298,791,792 Critonia quadrangularis 24:103 CRO 25:46 Croalbinecine 1:230,238,484,485 Crocetin 20:726;25:958;26:293297,299,301-303,305,307 ;28:314; 30:529 structure of 28:314;30:529 Crocetin di-(fl-D-digentiobiosy)-ester (crocin) 25:956 Crocetin di-(fl-D-gentiobiosy 1)-(fl-Dglucosyl)-ester 25:956,957 Crocetin di-(fl-D-glucose)-ester 25:956,957 Crocetin diglucose ester 25:955,959 Crocetin gentiobiose glucose 25:955 Crocetin gentiobiose glucose ester 25:959,966 Crocetin glucose esters 25:957;968 Crocetin glucosylation 26:307 Crocetindialdehyde 20:568,20:572 Crocin 25:956,957,959,964,965,968; 26:294,295,299,303,305 ;28:315 artificial pathway of 28:314 Crocin effects 28:316,319 on LTP-blocking effects of ethanol 28:316 on TNF-cz-induced cell 28:319 Crocin-1 26:299,300,301 Crocin-2 26:301 Crocin-3 26:301 Crocin-4 26:301 Crocin-5 26:301 Crocus sativus L. 22:518;26:293, 294,296,302-307;28:313-315 anti-tumor activity of 28:314,315 as coloring agent 28:313 ethanol extract of 28:315 effect on central nervous system 28:315 for flavoring 28:313 for sedative in convulsions
201
22:518 uses in medicine 28:313 Crocus sp. 26:297,299 carotenoids from 26:297,299 derivatives of 26:299 Cromolyn 22:170 Croomiajaponica 21:759 Cross coupling reactions 16:417 intramolecular 10:163 Pd-catalyzed 10:161,162 with (Z)-tributylvinyl-stannanes 10:162 Cross relaxation rates 2:60,61 Cross-aldol reaction 12:297 of (7R, 8aS)-8-hydroxy-8-methyl7-oxoindolizidine 12:297 Cross-aldolisation 12:289,298 Crossandra pungens 27:191 Crossaster papposa 7:298,299;15:61,69 Crossasteroside A 15:61 from Crossaster papposus 15:61 Crossasteroside P~ and P2 15:69 Crossasterosides A-D 7:299,301 Cross-Claisen condensation 11:114 Cross-condensation 30:218,219 products of 30:219 Cross-conjugated hydronaphthalene dienones photochemical 14:356 asymmetric cycloaddition of 14:505 C2-symmetric diols 14:469-518 C2-symmetric ketene acetal 14:505 chiral acetals from 14:469-518 rearrangement of 14:356 to 3-formyl chromone 14:505 Crossed Cannizzaro reaction 4:17,135 Crossed Wittig reaction 4:570 Crossed-Aldol condensation 1:596-603; 4:328,329 asymmetric induction in 4:328, 329 diastereoselective 1:596-603 Johnson-Yamamoto mechanism 1:600 Crossopetalum gaumeri 30:660,662 cytotoxic cardenolide from 30:660,662 Crossopteryx febrifuga 7:417,425
Crossostephium chinese L. 22:518 for infantile convulsions 22:518 Cross-polarization-magic angle spinning (CP/MAS) technique 23:124 application of 23:124 Crosus saliva L. 25:955,956 Crotalaria albida 25:93 Crotalaria madurensis 23:341 ;29:771 Crotalaria sp. 19:499 Crotmadine 23:341 Crotmarine 23:341 Croton 25:242 Croton cajucara 29:100 Croton genera 9:265;27:830 Croton lacciferus 23:341 Croton lechleri 22:361 Croton macrostachys 4:612 Croton oil 12:392;20:19;22:115;25:45 Croton oil induced edema (CRO) 25:45 Croton oil induced edema inhibition 25:46 Croton oil-induced ear edema 25:556 Croton oil-induced inflammator edema 25:55 inhibitory effects on 25:55 Croton tiglium 12:233;20:19;25:242 Croton zedoaria 29:90 trans-Crotonamide 8:156 cis-Crotonamide 8:156,157 Crotonate 8:410-412,427;20:836 trans-Crotonates 8:141,147,155,157 cis-Crotonates 8:155-157 synthesis of 8:155-157 (E)-Crotonic acid 11:340,341,359 (Z)-Crotonic acid 11:340,341,359 Crotonyl boronate addition 1:527 Crotyl halide 12:172 in zinc dust 12:172 with 4-acetoxy [3-1actam 12:172 Crotylborane reagent 12:36 Crotylboration 8:477;21:432 (-)-(E)-Crotyldiisopinocamphenyl borane 18:280,281 [E]-Crotylpotassium 8:477 [Z]-Crotylpotassium 8:477 Crown ether effect 11:234 Crown gall tumors 9:386 Crushed garlic 23:461
202
Crustacea 19:627;28:382;30:533 class of 28:382 Crustacyania 30:519 structure of 30:519 [3-Crustacyanin 30:533,534 Crustacyanin 6:161 Crustecdysone 19:463,627 Crynine-type alkaloids 26:615 Cryoenzymology 7:31 Cryomixture 18:836 Cryosurgery 30:405 Cryptanol 20:661 from Salvia candidissima 20:661 Cryptaustoline 3:423 Cryptaustoline iodide 6:482 Crypthecodinium cohnii 9:47 Cryptocarya caloneura 19:481 Cryptocarya pleurosperma 1:365 Cryptochlorogenic acid 23:744;25:921 Cryptocin 28:123 against phytopathogenic fungi 28:123 Cryptococcosis 2:422,433;22:60 Cryptococcus albicans 21:758 Cryptococcus albidus 5:292, 328;8:336,352 4-thioxylobiose from 8:336,352 Cryptococcus dimennae 26:618 Cryptococcus fagisuga 25:662 Cryptococcus flavescens 5:294 Cryptococcus laurentii 5:292,294,328 Cryptococcus magnus 26:618 Cryptococcus neoformans 2:292,322, 428,446 ;5:326-328,400,408 ;21:758; 22:57;248,299;23:8,10,136,242,481; 26:228,1127 Cryptococcus sp. 5:291,292,294,328; 21:192;22:248 Cryptococcus terreus 26:618 [~-Cryptoeutreptiellanone 6:150,151 Cryptogein 25:395 Cryptoj aponol 20:670 from Salvia napifolia 20:670 Cryptolepine 1:127;5:751,752;21:56; 26:1060 Cryptolepis sanguinolenta 5:751; 26:828,1060 cryptolepine from 26:828 Cryptolestes ferrugineus 8:227;19:154
Cryptoleuridine 1:365
Cryptomeriajaponica 2:402;19:246;
25:257,275;29:101 Cryptonoline iodide 6:482 Cryptophyceae 6:134-155 Cryptophycin 25:789 Cryptopine 21:68 Cryptopleurine 21:97 Cryptoporic acids 29:87 activity in AOS assay system 29:87 activity in TLO assay system 29:87 activity in PLA assay system 29:87 Cryptoporus volvatus 29:87 Cryptosporidiosis 26:788 treatment of 26:788 Cryptothetia crypta 21:252;25:712 spongouridine from 21:252 spongothymidine from 21:252 Cryptotrienolic acid 25:259 ct-Cryptoxanthin 20:727 Crysoeriol 20:712 from Salvia candidissima 20:712 Crystal structure 26:150,155;27:335 for abscisic acid 27:335 of 2'-bromopodophyllotoxin 26:150 Crystal-7 22:154 Crystallization- induced 13:76 asymmetric transformation 13:76 Crystallographic studies 27:821 Crystamidine 3:476 Crytotanshinone 22:175 Crytowolline 3:423 C-S bond 6:307,308 heterolytic dissociation of 6:307,308 homolytic dissociation of 6:307,308 CSF (colony stimulating factor) 25:455, 960,963 C-Sucrose 11:469,470 synthesis of 11:469,470 C-Trichodiene 13:520 14 CTX-3C 21:301 Cu (I)-catalysed 3:8
203
Cu (I)-Semiquinone 26:1273 Cualzorra 22:559 Cuanzin 8:283,284,289,293 antiarrhytmic activity of 8:283 antihypertensive activity of 8:283 Cuauhtemone 9:66 Cubebane skeleton 25:51,848 (+)-Cubebol 21:282 Cubitene 8:230 by c~-thiocarbanion-epoxide 8:230 from Cubitermes umbratus 8:230 synthesis of 8:230 Cubitermes 8:230;21:277 defence secretion of 8:220 Cubitermes umbratus 8:230 cubitene from 8:230 Cubugene 8:221 Cuculus micropterus 5:837 hemoglobin components of 5:837 Cuculus varius vahl 5:837 hemoglobin components of 5:837 Cucumaria echinata 15:94;28:596,720 neuritogenic activity of 28:720 Cucumaria fraudatrix 15:87,92 cucumariosides G1, C1 and C2 from 15:87,92 Cucumaria frondosa 7:277;28:720 2,6-dimethylnonane- 1-sodium sulfate from 28:720 frondogenin from 7:277 2,4,6- trimeth yl-no nane- 1-sodium sulfate from 28:720 Cucumariajaponica 7:275;15:87; 28:595 cucumarioside-A0-3 from 28:595 cucumarioside-A~-2 from 28:595 cucumarioside-A2-1 from 28:595 cucumarioside-A2-2 from 7:275; 15:87;28:595 cucumarioside-A3 from 28:595 cucumarioside-A4-2 from 28:595 cucumarioside-A6-2 from 28:595 cucumarioside-A7-1 from 28:595 cucumarioside-A7-2 from 28:595
Cucumaria koraiensis 28:599 Cucumaria lefevrei 15:92;28:596 from lefevreioside A~ from 28:596 from lefevreioside A2 from 28:596 from lefevreioside B from 28:596 from lefevreioside C from 28:596 Cucumariidae 7:275,277,280 Cucumarioside A2-2 7:275,276,15:87 Cucumarioside C1 & C2 7:275,276 Cucumarioside G~ 7:275,277,281 Cucumarioside G2 15:89 from Eupentacta fraudatrix 15:89 Cucumariosides G1, Ci and C2 15:87,92 from Cucumaria fraudatrix 15:87,92 Cucumis CMCTI-I 29:614 Cucumis CMeTI-A 29:614 Cucumis colocynthis L. 22:518 for epilepsy 22:518,519 Cucumis melo 25:390;29:614 Cucumis sativus 29:614 Cucumis sp. L. 22:518 for epilepsy 22:518 Cucumisin 25:390 Cucurbic acid 6:557 Cucurbita maxima 29:614 Cucurbita pepo 29:615 Cucurbita sp. 29:590 Cucurbitaceae 5:743,744,750; 21:634,730 saponins from 21:645 Cucurbitacin 20:4,13 Cucurbitacin B 5:750;22:97;26:868 glycoside of 5:750 Cucurbitacin D 5:750 Cucurbitacin E 5:750;22:97 glycoside of 5:750 Cucurbitacin F 25:59 Cucurbitacin I 5:744,751 Cucurbitacin J 5:744,751 Cucurbitacin L 5:750 glycoside of 5:750
204
Cucurbitane 25:50,57,59 23,24-dihydrocururbitacin F 25:50,57,59 Cucurbitane 5:744,750;22:95 Cucurbitane triterpenoids 24:249 Cudrania cochinchinenesis 28:203 Cudrania tricuspidata 28:203 Cudraphenone B 28:230 biological activity of 28:230 Cudraphenone D 28:230 biological activity of 28:230 CuI-tributylphosphine complex 4:556, 557 tandem Michael addition with 4:556,557 Culcia novaeguinea 7:298;15:69 Culcitoside C~ 15:69 Culcitoside C4-C8 15:71 Culcitosides C~-C3 7:96,109,110 cumambrin A,B 7:235 cyclases 7:96,109,110 diterpene synthetase 7:109,110 from Culcita novaeguinea 7:298 sesquiterpene synthetase 7:109,110 Culex pipiens fatigans 3:157 Culex pipiens pallens 21:252 Cullmorum 6:219,220;9:206, 207,215,216 Culmorone 6:219,220,536 Culture medium 17:432 effect on prod. of polyphenols 17:432 Cumambrin A 27:576;29:90 activity in NFkB assay system 29:90 Cumambrin A,B 7:235 Cumambrin B 27:576 C27-p-umaroxy-ursolic acid 20:6 Cuminaldehyde 29:83 activity in AM bioassay system 29:83 Cuminum 29:579 Cuminum cyminum 28:427 acaricidal activity of 28:427 Cuminyl alcohol 29:83 activity in AM assay system 29:83 Cumulated ylides 4:658
Cunningham 19:627 Cunninghamella 25:172 Cunninghamella blakesleana 23:22,42;25:172,173 Cunninghamella echinulata 20:792 Cunninghamella elegans 20:214 Cunninghamia lanceolata 25:251; 29:101 Cupalaurenol 5:368,7 Cupalaurenol acetate 5:368,7 Cuparene 8:12 Cuparene-related sesquiterpenes 17:7 (-)-c~-Cuparenone 10:407 (+)-a-Cuparenone 10:407 Cupolamide A 26:1190 Cuprate 1:456,457,459,460 Cupressaceae 21:615;25:246,249 Cupressus sempervirens 25:253 Curacin A 25:732,733,876 Curacin B 25:876 Curacin C 25:876 Curacin D 25:876 Curacins 25:876 Curan-type Strychnos alkaloids 1:33 Curare alkaloids 20:269 (-)-Curcuhydroquinone 23:164 (-)-Curcuhydroquinone- 1-monoacetate 23:164 Curculigo latifolia Dryand. 15:36; 27:18,39 curculin from 27:18,39 Curculigo orchioides 21:651 ;24:145, 146;25:227 Curculigosaponin G 24:145,146;25:227 Curculin 15:36 from Curculigo latifolia 15:36 Curcuma 23:825 Curcuma aromatica 22:518; 24:269;27:852 ;29:577 for convulsions 22:518 Curcuma comosa 26:884 anti-inflammatory activity of 26:884 Curcuma longa 8:52;13:660;17:363, 373,377,379;20:734 ;21:616;24:272, 274 ;25:469,476;26:457,474,882,887; 27:852;29:695 curcumin from 26:887 hepatoprotective activity of
205
25:469 serum transaminase activity of 25:469 Curcuma phaeocaulis 24:274 Curcuma sp. 17:358;26:905 Curcuma tinctoria 17:357 Curcuma xanthorrhiza 17:364;23:836; 24:274,288;26:883,884;27:852;29:87 Curcuma zedoaria 24:272;25:172;29:87 Curcumanolide B 23:827 Curcumene 5:777-778;23:181 ~-Curcumene 5:803-805,20:6;23:830 (+)-y-Curcumene 8:39 Curcumenol 29:90 activity in HPT assay system 29:90 Curcumia longa L. 25:469 hepatoprotective activity of 25:469 serum transaminase activity of 25:469 Curcumin 13:660,357,363,374,379; 17:374;20:729,734,772;21:616; 23:316,832;24:215-264 ;26:305 anti-tumor promoter 24:215-264 Curcumin 1-III 26:474 Curcumin (turmeric yellow) 25:44,469, 470,541 Curcuminoids 24:216 Curcuphenol 5:804;23:164 (-)-Curcuphenol acetate 23:164 (-)-Curcuquinone 23:164 (+)-Curcuquinone 8:39 Curdione 23:825 Curtius degradation 19:145 Curtius reaction 12:448,458 Curtius rearrangement 1:6,51,309,637, 638;19:68,79;21:435,746;26:1237 Curtius-type reaction 13:95 Curtobacterium pusillum 23:92 Curucumanolide A 23:836 Curucumanolide B 23:836 Curvularia lunata 9:412,417,418; 25:254,260,261,263;26:227 Curylus heterophylla 23:403 Curzenone 827 Cuscohygrine 22:724 Cuscuta europea L. 22:518 for fits 22:518
Cuscuta reflexa 25:944,945;29:573 Cushman study 27:925 Cussonia barteri 7:427;21:673 oleanolic acid glycoside from 21:673 Cussonia spicata 7:427,435 Cusumis sativa 24:57,60 Cutaneous leishmaniasis 30:742 treatments for 30:742 use of medicinal plants 30:742 Cutleria multifida 21:306 CVE 30:768,769,770,773,775,776 against Listeria 30:768 against listerial infection 30:768 as therapeutic agent 30:773 as prophylactic 30:773 effect on expression of mRNA 30:770 effect on growth of Listeria monocytogenes 30.769 in antigen-specific response 30:773 in mice 30:773 on IFNy mRNA expression 30:775 on IL- 12 mRNA expression 30:775 therapeutic potential of 30:768 to control allergy 30:776 CVE-treated MAIDS 30:769,770 Listeria antigen in 30:770 DTH response in 30:770 CVS 25:443,445,447,450 antimetastatic effect on 25:441 CVS induced antitumor immunity 25:454 antitumor effect 25:440 resortive effect on progenitor cells 25:448,449 and tumor specificity 25:442 Cyamopsis tetragonolobus 26:1139 (+)-Cyanidanol-3 22:429 Cyanide versus isocyanide formation 3:207 Cyanidin 3-galactoside 23:745,750 Cyanidin 3-glucoside 23:749,752 Cyanidin 3-O-galactosides 22:634 Cyanidin 3-rutinoside 23:746 Cyanidin 3-sophoroside 23:750
206
Cyanidin 3-sophoroside-5-glucoside 23:757 Cyanin chloride 20:738 4-S-Cyano derivative 8:335,336 Cyano trapping 1:105 Cyano [3-C-glycosides 10:372 1,2-O-Cyano (p-metho xy)benzylidene- c~D-galactose 14:252 2-Cyano- 1,1-dimthylethyl 4:285 2-Cyano-4-O- [3-D-glucopyranosyltrans-buten-2-ol 21:738 2-Cyano-6-oxazolo-piperidine 12:351 2-Cyano-azadiene Diels-Alder reaction 16:458 Cyanobacteria 21:303,367;23:234,344 Cyanobacterial hepatotoxins 9:496-499 Cyanobacterial inhibitory compounds 26:357-364 Cyanobacterial origin 20:887-913 Cyanobacterial toxicity 26:376 Cyanobactericides 26:382 c~-Cyanobenzyl alkyl ether 14:473 synthesis of 14:473 Cyanoborohydride 8:205 Cyanocobalamin 9:598,603,606 Cyanocycline A 10:103 antitumor activity of 10:103 Cyanocycline F 10:104 Cyanoepithio alkanes 26:1074 2-Cyanoethyl group 4:285 bis-(2-Cyanoethyl) phosphorochloridate 8:74 Cyanogen bromide 2:34 fragmentation of glucoamylase 2:34 Cyanogen iodide (ICN) 28:336 for cyanation 28:336 for cyanation of aromatic compounds 28:336 of alkenes 28:336 Cyanogenetic glycoside 15:226 Cyanogenic glucosides 21:737;22:75 7-Cyanogenic glycoside 21:738 Cyanoglycosides 30:453 Cyanohydrin 8:198;21:740 cyclization of 8:198 synthesis of 8:225,226
Cyanohydrin ether 8:177 alkylation of 8:177 cyclization of 8:178 Cyanomorpholino sugar 14:21 Cyanonaphthyridinomycin 1O:103,104 Cyanophyceae 6:134 Cyanophyta 10:250 c~-Cyanopiperidine 19:35-36 [3-Cyanopropanal dimethylacetate 21:406 Cyanopropylsiloxane 9:456 15-Cyanopuupehenone 21:363 3-Cyanosampangine 23:6 4-Cyanosampangine 23:6 Cyanosiloxane 9:454,456 (-)-l-Cyanovinyl (1' S)-camphanate 14:179 1-Cyanovinyl (1R)-camphanate 12:340 (+)- 1-Cyanovinyl ( l'R)-camphanate 14:179 from (1' R)-camphanic acid 14:179 1-Cyanovinyl (1S,5R,7S)-3-ethyl-2-oxo6,8-dioxa-3-3-azabicyclo [3.2.1 ] octan-7-exo-carboxylate 2:340 3-Cyanovoacangine 5:124 3-C-(c~-Cyano-c~-ethoxycarbonyl) methylene derivative 10:412 Cyantions 1:612,613 diastereoselective 1:612,613 of acetals 1:612,613 Cyasterone 25:59 Cyathocaline 20:485 Cyathus sp. 24:942 cyathanes from 24:942 Cybister tripunctatus 5:700 Cycadaceae 21:97 Cycas cricinalis 25:529 Cycas revoluta 29:578 Cycasine 21:97 Cyclachaenin 5:728,729 Cyclaradine 8:148 Cyclase 7:109,110 synthesis of 8:298 from sweet marjoram (Marjoram hortensis) 11:222 diterpene synthetase 7:109,110
207
sesquiterpene synthetase 7:109,110 Cyclase activity 30:639 ofMaytenus aquifolium 30:639 ofSalacia campestris 30:639 Cyclazocine 30:198,199 3-carboxamido analogue of 30:198 structure of 30:199 Cyclea atjehens& 20:552 Cyclea barbata 20:522 Cycleahomine (bisbenzylisoquinoline) 29:578 effects on ACE 29:578 Cycleanine 25:472,476;26:824 Cycleatjehenine 26:824 Cycleatjehine 26:824 Cyclic adenosine monophosphate 25:260,509,598 Cyclic adenosine monophosphate (cAMP) phosphodiesterase 24:855 Forsythia suspensa inhibition of 24:855 Cyclic adenosine-5'-diphosphateribose 25:547 Cyclic adenosine-5'-diphosphateribose (CADPR) nicotinic acid adenine dinucteotide phosphate(NAADP) 25:516 Cyclic ADPR 25:517 Cyclic amino acids 13:507-512 synthesis of 13:507-512 Cyclic AMP 7:387 Cyclic AMP phosphodiesterase 5:512, 513,520;25:539 3',5'-Cyclic AMP-dependent protein kinase (PKA) 25:512 Cyclic AMP-dependent protein phosphorylation 25:483 3'-5'-Cyclic AMP-sensitive cation channels 25:483 Cyclic dependent kinase 25:4,798,799 Cyclic depsipeptides 21:296 Cyclic dienes 8:141 Cyclic diterpenoids 30:707 classification of 30:707 Cyclic ene-dione acceptors 4:709,711 in Michael reaction 4:707-709
Cyclic enones 14:502 [2+2] photocycloaddition of 14:502 with chiral ~,[3-unsaturated acetals 14:502 Cyclic GMP-phosphodiesterases 25:54I Cyclic halo ether compounds 19:411461 from marine origin 19:411-461 synthesis of 19:411-461 Cyclic hexadepsipeptides 13:533 Cyclic hexapeptide 22:297 Cyclic hydroxamic acid 27:199 c~-hydroxylation of 27:199 Cyclic ketones 6:313-315,332,333 synthesis of 6:313-315,332,333 Cyclic nucleotide phosphodiesterase 25:512 Cyclic oligopeptides 24:304,307 Cyclic oligosaccharides 27:365 Cyclic peptide 23:341 Cyclic peroxides 5:353-355;23:341 Cyclic polypeptide inhibitors 27:879 Cyclic steroidal glycosides 15:59,60 Cyclic sulfides 8:205 Cyclic systems 6:33-38 synthesis by modifications of 6:33-38 de novo synthesis of 6:33 Cyclic voltammetry 30:543 Cyclic ~-keto esters 1:697-701 reduction with yeast 1:697-701 Cyclic-Cram diastereoselectivity 12:297 Cyclindramide 21:411 Cyclindrocarine 19:112 Cyclindrocarpidine 5:128 Cyclitol derivatives 7:156,157 Cyclitols 13:6 Cyclization 11:221,222;30:213,462,717 (+)-(4R)-~-terpinyl from 11:221,222 acyliminium-mediated 10:125 amide iminium ion 10:87 asymmetric 10:631-633 azido-olefin 13:447,448 bicyclic keto ester from 14:509 by C-C bond formation 10:218-231
208
by C-O bond formation 10:202 by diphenyl phosphoryl azide 10:641,644,652,656,657 by sodium bistrimethylsilylamide 6:540 catalytic 8:278 Dieckmann 13:445 enzymatically controlled 11:287 in silver (I) triflate 12:81 intramolecular 10:631-633; 11:253,254 ;12:156 iodotrimethylsilane mediated 11:109 Lewis acid mediated 10:87 ligase catalyzed 14:304,305 mechanism of 6:314,315;7:335338,358-360 of (-)-(3 R)-linalyldiphosphate 11:221,222 of (L)-glutamic acid 6:438-440 of acyclic nucleoside derivative 10:588,592 of allyl glycidyl ether 10:588, 589 of c~-mono-alkoxylated piperazinediones 12:90 of cyanohydrin ethers 8:194 of epoxy alcohol 10:599,600 of epoxy allylic ether 10:590, 591 of glucose 11:219 ofhexapeptide 10:289,290 of ketoesters 4:328-330 of lycopene 7:334-354 of neurosporene 7:334-354 of nitroketone 6:447,448 of oligoribonucleotides 14:304,305 of 3S isomer of 2,3-epoxy-2,3dihydrosqualene 30:717 of squalene 30:717 of triterpenoids 30:717 of vinyl sulfoxides 10:673-676 of vinyl sulfoximines 10:679 of ot-diazo ~-keto ester acetals 14:509 oxetane ring formation by 10:588,589 oxetanocin A synthesis by
10:588-592 palladium catalysed 1:258 reductive 8:278 regioselectivity of 6:540 Rh (II)-catalyzed 14:509 stereochemistry of 7:338-354 stereoselectivity of 6:540 transannular 13:440 using TFA-water mixture 30:462 via SN2 displacement 11:253, 254 with copper (II) perchlorate 12:85 with diphenyl phosphoryl azide 10:289,290 with Nicolaou reagent 10:121, 122 with pyridinium chlorochromate 11:93,94 Cyclization reaction 6:15,43,44 [2+2] cycloadditions 6:15,43,44 diastereoselective 14:506,507 in (+)-A 9(12)capnellene synthesis 6:43,44 in cadinane synthesis 6:15 in elemane synthesis 6:15 in germacrane synthesis 6:15 of 6-octen-l-al 14:506,507 Rh(I) catalyzed 14:506,507 Cyclized branched oligoribonucleotides 14:486,489 (-)-Cyclizidine 12:305,306 biological activity 12:305,306 Cyclo-( 1-3 )- [3-galactooligosaccharide s 14:237 Cyclo-(1-6)-[3-galactooligosaccharides 14:237 Cyclo-(L-Pro-L-thiopro) 25:829 Cyclo-(L-Pro-Met) 25:829 9[3,19-Cyclo- 11-oxo steroidal alkaloids 2:205,206 9[3,19-Cyclo-20-oxo-(16-17) steroidal alkaloids 2:2079,19-Cyclo-5 ot,9[3-1anostane 27:447 Cycloacanthaside F 25:197 Cycloaddition 16:7,47 1,3-dipolar 1:247-250 asymmetric 1:371-375;11:300
209 by 3-hydroxy- 1-arylthiobutene 4:477 by chlorosulfonyl isocyanate 4:475 E-exo-transition state 1:370,371 enolate induced 1:502-503 intramolecular [3+2] 1:247-250 intramolecular [4+ 1] 1:247-250 intramolecular nitrile oxide [INOC] 1:477,480,481 ionic 5:793 lanthanide catalyzed 1:413,415 MgBr2 mediated 1:474 Ni (O)-catalysed intramolecular 3:78,79 of (N-acryloyl) bornan- 10,2sultam 11:307,308 of alkene 11:468 of levoglucosenone 14:270,271 2+2]-Cycloaddition 1:263,343;4:475; 8:45,185,207;11:15-20,45-47; 12:116,150-152,160,161,173,193, 416;15:266;16:127,470,732,733 carbocyclic oxetanocins synthesis by 10:610-616 enantioselective 10:610-616 in homoerythrinan synthesis 3:481,478 of allene 16:127 photochemical 16:125,469 with dichloroketene 13:6,36 synthesis of quinoline skeleton 3:385-397 4+2]-Cycloaddition 1:282,323,420, 465;8:45,185,207;11:11,13,14,16, 260-267 ;16:4,444,493,732;19:108109,148,221,227 acid catalyzed 4:4 cycloaldolization 4:4,11,17,18, 22,23 diasteroselective 12:424,425 high pressure Eu (fod)3-mediated 4:121,143 in (+)-A -9(12) capnellene synthesis 6:43,44 in lincosamine synthesis 4:154 in purpurosamine C synthesis 4:115 of 2-alkenyltropolones 5:799
of 3-[(1S)-2-exo-alkoxy- 1 apocamphanecarbonyl]-2oxazolones 12:424,425 of c~-amino aldehydes 4:111 ofkojic acid 5:799 reverse stereoselectivity of 4:122 to dialkyl azodicarboxylates 12:424,425 transannular 5:796,797 [3+4]-Cycloaddition 1:378,522,523 1,3-Cycloaddition 1:448,449 [8+2]-Cycloaddition 1:568 [6+3]-Cycloaddition 1:569 [6+4]-Cycloaddition 1:571 intramolecular 1:571 of cyclopentadiene with tropone 1:570 of dienes to tropone 1:569-571 of 2-alkenyltropolones 5:799, 800 [4+4]-Cycloaddition 11:17 [6n+47t]-Cycloaddition 12:238 [2+2]-Cycloaddition 24:190,191 of dichloroketone 24:190,191 [2+3]-Cycloaddition 3:469 4-oxo-erythrinans by 3:469 [5+2]-Cycloaddition 8:160-163,16:552, 553;12:260,261 [3+2]-Cycloaddition 8:402; 19:66,78, 80,174,367 of 2-azaallyl fragments 1:324 of azomethine 8:402 of azomethine ylide 19:80 intramolecular 19:367 stereospecific 19:367 Cycloaddition processes 12:250-261 for tigliane ring system 12:250-261 [3+2]-Cycloaddition reaction 12:155 of nitrone 12:155 to benzyl crotonate 12:155 Cycloaddition reaction 14:502-505,747, 19:226 diastereoselective 14:502-505 with 1-trimethyl silyloxybutadiene 14:747 of quinone monoketals 5:796, 797
210
[2+2]-Cycloaddition-fragmentation 12:194,195 [4n+2n]-Cycloadditions 1:566-571 intramolecular tropone-olefin 1:568 inverse electron demand 1:566 with tropone as diene 1:566-571 Cycloadduct 12:425 chiral synthon of 2-amino alcohol from 12:425 trans-4-me tho x y-2-o xazo lidinone
from 12:425 [5+2]-Cycloadducts 16:555-559 [4+2]-Cycloadducts 16:732 Cycloalliin 23:458,461 Cycloalpegenin 25:179,184, 187,190,201 Cycloalpigenin A 25:184,201 Cycloalpigenin B 25:201 Cycloalpigenin C 25:201 Cycloalpioside A 25:201 Cycloalpioside C 25:201 9,19-Cycloanost-24-ene-3fl-ol 25:190 Cycloanthogenin 25:187 Cycloaraloside A 194 Cycloaraloside B 25:195 Cycloaraloside C 25:195 Cycloaraloside D 25:195 Cycloaraloside E 25:194 Cycloaraloside F 25:195 Cycloarbicoside A 25:202 Cycloart-24-en-3-one 9:288,289 Cycloart-24-en-3 [3-ol 9:288,289 24R-Cycloartan-3fl, 6a, 16/3-24,25pentaol, 6-dehydroxyc yc loastragenol 25:184 Cycloartane 9:267;25:61,52 Cycloartane derivatives 27:448 Cycloartane glycoside 25:221 Cycloartane saponins 25:183 Cycloartane structure 27:4 of genins 27:4 Cycloartane-type triterpene glycoside 27:473 Cycloartene triterpenes 10:151 Cycloartenol 17:622;27:447;29:586 effects on CHY 29:586 Cycloartenol ferulate 25:61
Cycloartenyl linoleate 9:461 Cycloartenyl palmitate 9:461 Cycloartobiloxanthone 28:201,230 biological activity of 28:230 from moraceous plants 28:201 Cycloasgenin C 25:185 Cycloastragenol 25:179,184,185, 186,187,190,191,192,215,217,225 Cycloastragenol-6-O-glucoside 25:224 8,14-Cycloberbines 1:188,189,192-197 Cyclobullatine-A 2:207 [2+2]Cyclobutane formation 10:611, 613 Cyclobutanes 16:553,554 protic acid rearrangement of 16:553 rearrangements of 16:554 Cyclobutanol 14:647 Cyclobutanone 10:618 oxaspiropentane rearrangement by 10:618 Cyclobutanone-ring expansion 3:23,24 (-)-E-Cyclobuxaphylamine 2:197,198 (-)-Z-Cyclobuxaphylamine 2:198,199 Cyclobuxomicreine 2:207 Cyclobuxophylline 2:207 Cyclobuxophylline-O 2:207 Cyclobuxosuffrine 2:207 (+)-Cyclobuxotriene 2:194,195 (-)-Cyclobuxoviricine 2:193,194,204 Cyclobuxoviricine 2:207 Cyclobuxoviridine 2:207 (+)-3,5-Cyclocamphanone 4:646 Cyclocanthaside D 25:197 Cyclocanthogenin 25:184,185,197 Cyclocanthoside A 25:197 Cyclocanthoside E and G 25:227 Cyclocanthoside G 25:197 Cyclocarbamations 12:411,414 Cyclocarbonate group 6:285,286 Cyclocarposide 25:193 Cyclocarposide B 25:193 Cyclocarya paliurus 27:15,28 cyclocarioside A from 27:15 cyclocarioside I from 27:15 Cyclocephaloside 25:200 Cyclocephaloside II 25:193
211 (24S,25S)-24,26-Cyclocholesterol 9:37 from Spheciospongia vagabunda 9:37 Cyclocholesterol 9:41 Cyclocinamide 25:757 Cyclocinamides A 25:761,762 c~-Cyclocitral 28:406 acaricidal properties of 28:406 (R)-(-)-Cyclocitral 6:31 pallescensin-1 from 6:31 [3-Cyclocitrol 14:673-676;20:570; 26:354;28:406 acaricidal properties of 28:406 condensation of 14:673-676 taxodione from 14:673-676 with 3-isopropyl-4-methoxybenzyl chloride 14:673-676 (-)-Cyclocolorenone 14:360 (+)-Cyclocolorenone 21:281 Cyclocolorenone sesquiterpenes 21:281 Cyclocondensation 4:130,145 and threo-selectivity 4:130,145 Lewis acid catalyzed 11:446-451 Mg Brz-catalyzed 1:415,417; 11:451 with Ce(OAc)3-BF3.OEt2 1:420,421 with Danishefsky's diene 4:122,130 with Eu FOD 1:420,421 with L-serinal 4:122 with N, O-protected c~-amino aldehyde 4:130 with silyloxydienes 4:113 Cis-f3-Cyclocostunolide 2:280,281 Cyclocurcumin 17:363;26:902 (E,E)-2,6-Cyclodecadiene 8:177 (E,Z)-2,6-Cyclodecadiene 8:177 Cyclodecadienone 8:247 by [3+3]-Oxy-Cope rearrangement 8:247 by Diels-Alder reaction 8:249 photocycloaddition 8:250 Cyclodepsipeptides 5:419,10:251, 252,263 Cyclodercitin 25:893,894 Cyclodesipeptides 25:768,884
[3-Cyclodextrin 27:368,369 for the separation of enantiomers 27:369 Cyclodextrin-hiba oil 21:620 Cyclodextrins 7:34;27:365,368 chromotographic techniques for 27:368 c~-Cyclodextrins 27:365 y-Cyclodextrins 27:365 structure of 27:366 Cyclodextrin-type compound 27:365 from (+)-a-D-glucose 27:365 Cyclodimerization 4:92,93 with DEPC 4:92,93 of tetrahydroisoquinoline precursors 6:495 7,20-Cyclo-ent-kaurane skeleton 15:167 7,20-Cyclo-ent-kaurenoids 15:112 Cycloeucalenol 9:39 obtusifuluol from 9:39 Cycloeudesmol 6:40 from Chondria oppositiclate 6:40 isocycloeudesmol relation to 6:41 (+)-ct-selinene conversion to 6:40 synthesis of 6:41 Cyclofriedo-oleanone 7:152 X-ray analysis of 7:152 from Euphorbia nerifolia 7:152154 Cyclo functionalization 6:427,428 of ethylurethanes 6:427,428 with phenylselenyl chloride 6:427,428 Cyclogalegenin 25:179,184,187, 191,196,218,225,227 Cyclogalegenoside A 25:196 Cyclogaleginoside B 25:196 Cyclogaleginosides 25:191 Cyclogibberellane 6:207 9,15-Cyclogibberellin 6:206 Cycloglycofoline 13:348,349,370-372 cis-Cyclogonionenin 18:222 trans-Cyclogonionenin 18:222 Cyclohemiacetals 27:196 synthesis of 27:197
212
Cycloheptanone 8:35 Cycloheptatriene 30:473 as achiral non-carbohydrate 30:473 Cycloheptene-6,7-dicarboxylate 9:226 Cycloheptenone enolate 6:29,30 in perforenone synthesis 6:29,30 Robinson annulation of 6:29,30 Cyclohex-2-enone 27:335 ofabscisic acid 27:335 Cyclohexadiene 12:11,12 1,4-Cyclohexadiene 27:342,343 of boat-boat inversion potential 27:343 Cyclohexadienones 5:343-346 Cyclohexane ring system 6:5,6,29,30 annulaton of 6:5,6,29,30 Cyclohexane- 1,2,-diamine 25:345 cis-l,2-Cyclohexanediol 10:324,325 trans- 1,2-Cyclohexanediol 10:324,325 1,2-Cyclohexanediones 12:376,377 bis-Fischer indolization of 12:376,377 Cyclohexanhexaol (inositol) 7:37 Cyclohexanol 11:343 Cyclohexanone 8;36;30:141 aromatization of 14:637,638 by chiral lithium amides 14:571, 572 kinetic deprotonation of 14:571,572 monoacylation of 30:141 prochiral 4-substituted 14:571, 572 Cyclohexanone aldehyde 6:61 bromochamigerene from 6:61 spiroannulation of 6:61 spiro[5.5] undecenone derivatives from 6:61 Cyclohexanone bis-epoxide 1-oxaspiro [4,5] decane ring system 21:389 Cyclohexanone derivatives 27:338 2-Cyclohexen- 1-one 11:337,338 aldols from 11:337,338 kinetic deprotonation 11:337,338 with 4-pentenal 11:337,338 1-Cyclohexene carboxyl CoA 11:190,191
Cyclohexene derivatives 4:581 synthesis of 4:581 Cyclohexene imides 12:378 arcyriaflavin A from 12:378 bis-2-chlorophenylhydrazones from 12:379 N-methylarcyriaflavin A from 12:378 1-Cyclohexenecarboxylic acid 1l: 191 trans-Cyclohexenecarboxylic acid 11:340,341 by Diels-Alder addition 11:340,341 from (E)-crotonic acid 11:340,341 from butadiene 11:340,341 deprotonation of 14:658 with lithium diisopropyl amide 14:658 Cyclohexenone ring 27:344 ofabscisic acid 27:344 Cycloheximide 25:58 Cycloheximide-induced amnesia 25:958 Cyclohexylamine 15:4 Cyclohexylidene 24:883-887 potentiating effects on neuromuscular blocking action 24:883-887 (3S,4S)-Cyclohexylstatine 12:432,433 from (4S,5S)-5-allyl-4-methoxy2-oxazolidinone 12:432,433 Cyclohexylstatine (3S,4S)-4-amino-5cyclohexyl-3-hydroxypentanoic acid) 12:432 renin inhibitor of 12:432 Cyclohexylundecanoic acid 11:190 wCycloisomerization 8:297 of cis, cis-3-carboxymuconic acid 8:297 913,19-Cyclolanost-24-ene-3fl-ol 25:181 Cyclolaurene 17:7 Cyclolaurenol 17:7 Cyclolinteinone 29:111 activity in COX bioassay system 29:111 activity in iNOS bioassay system 29:111 activity in NFkB bioassay system 29:111
213
Cyclolithistide A 26:1190 Cyclolodecene 6:541 Cyclomalyanine - B 2:207 Cyclomicrobuxeine 2:207 Cyclomicrosine 2:207 Cycloneosamandaridin 9:305 Cycloneosamandion 9:305 (1Z,5Z)-l,5-Cyclooctadiene 26:81,88 Cyclo-octanoid terpenes 6:33-36 synthesis of 6:33-36 L-Cyclooligosaccharide 8:359-370 Cycloorbicoside G 25:202 Cycloorbigenin B 25:185,187,202 Cyclooxygenase inhibitor 25:593; 28:16,17 aspirin as 30:594 broussoaurone A as 28:16,17 broussoflavonol F as 28:17 Cyclooxygenase inhibitory activity 26:46,556 ofjenisseensosides A-D 26:46 Cyclooxygenase pathway 25:263, 274,593 Cyclooxygenase/Lipooxygenase 25:615 Cyclooxygenase-2 (COX-2) genes 26:927 Cyclopamine 7:16,17,21,22;21:97; 23:583,563,565,575 structure of 23:583 Cyclopapilosine -D 2:207 Cyclopenta [c] pyran 7:458,459 cis-Cyclopenta [d] pyrimidine-2,4,dione 22:291 Cyclopentadecanones 10:330,331 Cyclopentadiene 2:162,307,308;8:141147,150,153;11:307,308;22:204 Cyclopentane annulation 13:6,16 Cyclopentane ring system 6:6-8,30,31 annulation of 6:6-8,30,31 cis- l,2-Cyclopentanediol 10:324,325 trans- 1,2-Cyclopentanediol 10:324,325 1,2-Cyclopentanediol 8:20 Cyclopentanoid monoterpene alkaloids 7:443,444 Cyclopentanoid natural products 4:581 Cyclopentanoids 8:139 Cyclopentanol 14:647 formation of 14:647
in 6-alkoxy ketones 14:647 ring expansion of 8:245 Cyclopentanone 6:428,429;22:199 1-piperidenines from 6:428,429 Cyclopentanooxazolidine 12:295 Cyclopentendialdehyde 7:465,466 Cyclopentene annulation 13:14 Cyclopentenpolyols 7:475 Cyclopentenyl diene isocyanide acid 21:363 Cyclopentylamine derivative 8:397 (S)-Cyclopentylglycine 13:510,511 Cyclopeptolides 10:280,281 Cyclophellitols 19:351-388 Cyclophosphamide 25:431 Cyclophosphamide treatment 25:447 Cyclopia 7:16 Cyclopiazonic acid 28:119 as calcium uptake inhibitor 28:119 Cyclopic embryo 23:572 Cyclopic lamb 23:567 Cycloposine 7:16,17;23:565 Cycloprodigiosin 8:272 Cyclopropanation 14:489-491 diastereoselective 14:489-491 exo 1:252,253 intramolecular 16:222 of allylic alcohol-acetal 14:490,491 ofdiazo ketones 3:39,40 of ten-membered enones 8:179 of unsaturated acetal 14:490 with Me3S (O)I-NaH 8:186 with oxysulfurane 8:183 cis-Cyclopropane 8:184,185 trans-Cyclopropane 8:183,184 Cyclopropane aldimine 12:287 Cyclopropane methylsteroid 27:470 Cyclopropane ring opening 1:250-253 Cyclopropane- 1,2,3-selenadiazole 9:122,123 Cyclopropanecarbonitrile 12:287 Cyclopropanedicarboxylic acid 10:618 Cyclopropanes 3:288,232,407 Cyclopropanone 8:36 Cyclopropanone sliding reaction 6:37,48
214
(+)-A-9(12)-capnellene from 6:48 in (+)-dactylol formation 6:237 in eight-membered marine compounds 6:37 Cycloproplyalanine 21:297 Cyclopropylimine 1:250,251,296 acid catalysed rearrangement 1:250,251,296 Cyclopropyl ketones 2:168,169 Cyclopropyl-carbinol rearrangement 3:23 Cyclopropylphosphonum salts 12:311 Cycloprotobuxine-C 2:207 Cycloprotobuxine-F 2:207 Cyclopseudohypericin 22:649; 30:607,608 structure of 30:608 Cyclopycnanthoside I 25:198 ~-Cyclopyrethrosin 27:554 Cyclorenierins 25:694 [2+2]-Cycloreversion 15:266 Cycloreversion 4:609 (-)-(2S,3R)-Cyclosarkomycin 8:150,152 D-Cycloserine 26:366 Cyclosieversioside A 25:193 Cyclosleversioside B 25:194 Cyclosieversioside C 25:193 Cyclosieversioside D 25:194 Cyclosieversioside E 25:192 Cyclosieversioside F 25:193 Cyclosieversioside G 25:194 Cyclospongiaqulnone-I 15:299 Cyclo spongiaquinone-II 15:299 Cyclosporine 5:128;21:225,226;22:58, 247,257 Cyclosporine A 10:256-58,299,20:894; 22:245 ;26:486;30:4 Cyclosporine C 21:226 Cyclostellettamines 21:56 Cyclosterol 16:324 Cyclotaxanes 20:3,11,80,100 Cyclotetrapeptides 10:250 Cyclotheonamide A-E 26:1179,1180 Cyclotheonamide B 25:715 Cyclotheonamide E2 26:1180 Cyclotheonamides 25:715 Cyclovirobuxeine-A 2:207 Cyclovirobuxeine-B 2:207 Cyclovirobuxine-D 2:207
Cyclovitamin D3 10:70 Cycloxygenase 25:47 inhibition of 25:47 9[3,19-Cyclo-A(6---~7) steroidal alkaloids 2:207 Cycnomorium songaricum 29:574 Cycopentannulation 1:551,552 Cyctoalpioside B 25:201 Cyerce cristallina 21:317 Cyercenes 21:317 Cylindramide 28:139 cytotoxic activity of 28:139 Cylindricine A and B 25:793 Cylindricines I and J 25:859,860 Cylindricins 25:857,859 Cylindrines F,G and H 25:859,860 Cylindrocarpon olidum 26:471 Cylindrocarpon sp. 27:871 Cylindrocladium ilicicola 21:215 ilicicolin-H from 21:215 Cylindrol B~ 25:790 Cylindrols 24:445-447 bovine brain FPTase activity of 24:446 related compounds 24:445 structures of 24:445 Cylindrospermopsis raciborskii 25:732; 26:352 Cylitol 25:920 [3-Cylodextrin 13:332 Cymbastela coralliophila 25:704 Cymbastela hooperi 25:689,814, 856;28:665 Cymbastela sp. 25:714,768,792,847 Cymbopogan winterianus 21:595 Cymbopogon citratus 28:398 essential oils from 28:398 Cymbopogonflexuosus 14:450,451 eudesm-11-en-4-ols from 14:450 intermedeol from 14:450,451 Cymbopogon nardus 28:398 essential oils from 28:398 p-Cymene 21:585,598,601;25:145 m-Cymene 28:406 acaricidal property of 28:406 Cymicilen 27:483 Cymol 20:13,16 Cynanchum decipiens 22:518 Cynanchum otophyllum 22:518
215
Cynanchum saccatum 22:518 Cynara scholaris 13:660 Cynara scolymus 23:752;25:943 Cynarin 13:660 Cynaropicrin 29:90 activity in NO assay system 29:90 activity in TNFot assay system 29:90 Cyneromycins 26:444,445 Cynidin IdB 25:613 Cynodon dactylon L. Pers. 22:518 for epilepsy and hysteria 22:518 Cynomorium songaricum 29:575 Cypenamine 8:474 Cyperaceae 9:391 ;27:766 Cyperene 23:546 (+)-6-epi-tx-Cyperone 10:408 13-Cyperone 14:406-413 from thujone 14:406-413 synthesis of 14:406-413 trienone from 14:406-413 (-)-7-epi-Cyperone 14:452,453 from (-)-carvone 14:452,453 (+)-intermedeol from 14:452,453 paradisiol from 14:453 Wolff-Kishner reduction of 14:452,453 ~-Cyperone 25:170,171 Cyperus aromaticus 22:399,400 Cyperus esculentus L. 22:518 for epilepsy 22:518 Cyperus iria L. 22:399 Cyperus monophyllus 22:400 Cyperus pilosus 22:400 Cyperus rotundus L. 22:401,518;24:272 for epilepsy 22:518 Cyperus serotinus 22:400 Cyphostemmin A&B 26:567 Cyprinus carpi 27:439;28:564 antitumor activity of 28:564 as diuretic 28:564 for eye fatigue 28:564 Cyproteptadine 26:1063 Cyptanol 20:670 from Salvia napiflia 20:670 [35S]Cysteine 21:322
Cysteine 23:255,468;30:836 (xz-macroglobulin inhibition by 30:836 Cysteine protease falcipain 25:331 Cysteine protease inhibitor 29:592 effects on cysteine protease 29:592 Cysteine proteases 26:800;29:569 aleurain as 29:569 bromelain as 29:569 Ca2+-regulated 29:569 calpains as 29:569 caricain as 29:569 cathepsin B as 29:569 chymopapain as 29:569 ficin as 29:569 from Plasmodium falciparum 29:569 in Alzheimer's disease 29:569 in gastric cancer 29:569 in type 2 diabetes 29:569 inhibition by 29:569 papain-like 29:569 protease actinidin as 29:569 type I pyroglutamyl peptidases as 29:569 Cysteine proteinase 25:375 Cysteine proteinase inhibtor 25:370 Cysteine sulfoxide 25:854 D-Cysteinolic acid 15:76;25:872 Cystic fibrosis 26:1151 Cystobacterfuscus 28:144 Cystodytes 25:894 Cystodytes dellechiajei 10:250 Cystodytes sp. 21:269;25:820;28:638 dehydrokuanoniamine B from 28:638 shermilamine C from 28:638 Cystodytes violatinctus 25:820;28:639 Cystodytin A 23:270 Cystodytin B 23:270 Cystodytins 25:821 Cystodytins A-C 10:250 Cystophora torulosa 9:322 Cystoseira 26:1121 Cystoseira balaerica 20:35 Cystoseira crinita 20:25,28,35 Cystoseira elegans 18:712,713
216
Cystoseira spinosa (var. squarrosa)
9:321 Cytarabin 21:136 Cytidine 5'-triphosphate 27:820 Cytidine diphosphate diacylglycerols 18:433 Cytisine 2:62,63;21:51,91,98,109; 27:276,280 (-)-Cytisine 15:522;26:487;27:281 Cytisus scoparius 15:525 (-)-3,13 a-dihydroxylupanine from 15:525 Cytochalasans 13:107-153 synthesis of 13:107-153 biogenesis of 4:620 Cytochalasin 25:874,875 Cytochalasin (B) bis-tetrahydropyranylether 13:116 Cytochalasin B 10:166;13:116-118,120; 21:96 synthesis of 10:166;13:116118,120 Cytochalasin C 13:148,149 synthesis of 13:148,149 Cytochalasin D 13:107-139 synthesis of 13:107-139 Cytochalasin E 13"107,114 Cytochalasin G 13:130,131 synthesis of 13:130,131 Cytochalasin H 13:125-129,134;15:353 synthesis of 13:125-129,134 Cytochalasin J 15:353 Cytochalasin K 13:107 Cytochalasins 8:213;21:96;24:549 antiviral microbial-derived compound 24:549 synthesis of 8:213 Cytochalasins N 15:353 Cytochalasins O 15:353 Cytochalasins P 15:353 Cytochalasins Q 15:353 Cytochalasins R 15:353 Cytochalasins S 15:353 Cytochrome 7:105 Cytochrome oxidase-inhibiting cyanide 25:513 Cytochrome P450 13:168;27:346 catalyzing aromatic
hydroxylation 5:456 by hydroxylation 27:346 Cytochrome P450 2El 21:654 Cytochrome P450 enzymes 21:654; 27:348 oxidation of 27:348 Cytochrome P-450 inhibitor 4:621 Cytochrome P-450 monooxygenase 25:318,597 Cytochrome P450-dependent monooxygenases 25:413;30:765 inhibition by chlorophyll 30:765 Cytochromes 18:914 Cytokine gene 25:470 Cytokine mRNA 30:771,775 expression in 30:771,775 RT-PCR analysis of 30:771,775 Cytokine production 26:921 ;30:689 inhibitory effect on 30:689 Cytokine receptors 27:825 Cytokine tumour necrosis factor c~ (TNF-ct) 26:916 Cytokine/cell growth factor 30:768 GM-CSF as 30:768 Cytokines 25:463;27:82;30:192,770 as pain mediator 30:192 HODEs induced genesis of 27:82 in mare- -~lians 27:82 neutrophds as 30:192 Cytokinesis-block micronucleus assay 21:642 Cytokinins 4:227-229;7:89,90,94; 20:531 ;25:367,379;26:581,583,584 6-benzylaminopurine (BAP) as 7:90 2,4-dichlorophenoxyacetic acid as 7:90 kinetin (6-furfuryl amino purine) as 7:90 Cytolylic/Cytostatic factors 23:132 Cytolytic activity 30:95 of mouse lymphocytes 30:95 Cytolytic cytostatic factors 23:132 Cytolytic lymphocytes (CTL) 25:273 Cytolytic T cells 25:453 Cytolytic T lymphocytes 25:271 Cytomegalo virus infections 25:431
217 Cytomegalovirus 30:394,404,412 biological properties of 30:404 pathogenetic properties of 30:404 Cytopathic activity 20:442;21:665,744 Cytopathic components 30:397 Cytopathic effect 24:483;30:397 of HIV-1 30:397 of HIV-2 30:397 Cytopathogenicity 15:76 Cytoplasmic guanylate cyclase 25:382 Cytoplasmic inhibitor protein 26:926 Cytoplasmic proteins 28:321 in apoptosis 28:321 Cytoprotective activities 21:655;26:224 Cytosal ascorbate peroxidases 27:736 Cytoseria unsenoides 22:519 Cytosine 19:516 Cytoskeleton 21:96 Cytosolic Ca ++ 30:383 elevation by G-protein 30:383 Cytosolic calcium mobilization 30:339 inhibition of 30:339 Cytosolic dehydrogenase activity 25:423 Cytosolic inositol (tris) phosphate 18:857 Cytosolic PIA2 25:717 Cytosolic sphingosine kinase 25:264 Cytostatic activity 18:775-778;20:796; 21:637;28:146 of eliamid 28:146 Cytostatic effect 26:924 Cytostatic T cells 25:453 Cytotoxic 12:390;24:799,845 against human neurablastoma NB-1 cells 12:390 biological activity 24:799,845 staurosporine 12:390 Cytotoxic action 25:477 of TMB (3,4,5,-trimethoxybenzoy) 25:477 Cytotoxic activity 4:101 ;5:84,342-346, 353 ;21:399,404,634,637,655,675; 23:78,96,172,177,180,186,234,235,2 85,296,299,301,308,313,346,649, 660,679,698,797,800,801; 24:309-318,837;26:216-218,452,470, 485;27:927;28:17,65,217,220,227,
468,470;30:156,589,590,624,691, 692 against KB cell line 30:692 against leukemia cells 23:74,186 demethylsonodione 30:589 of (-)-deoxypodophyllotoxin 30:589 of (-)-hernone 30:590 of (-)-nymphone 30:590 of (-)-yatein 30:590 of (+)-corytuberine 30:589 of (+)-epiaschantin 30:590 of (+)-epimagnolin 30:590 of (+)-epiyangambin 30:590 of (+)-hernovine 30:589 of (+)-laurotetanine 30:589 of (+)-magnoflorine 30:589 of (+)-malekulatine 30:590 of (+)-N- formyldehydroovigerine 30:589 of (+)-N- formylnornantenine 30:589 of (+)-N-formylovigerine 30:589 of (+)-N-hydroxyhernangerine 30:589 of (+)-N-methylhernangerine 30:590 of (+)-ovigerine 30:590 of (+)-ovihernangerine 30:590 of (+)-vateamine-2' [3-N-oxide 30:590 of 15-methoxycarbonyl nagilactone D 28:468 of 15c~-hydroxy-pristimerin 30:692 of 16-hydroxy podolide 28:468 of 1-deoxy-2c~-hydroxyagilactone A 28:468 of 2a-hydroxynagilactone F 28:470 of 3,5-diiodetyramine 23:235 of 3-deoxy-2 cz-hydroxynagilactone E 28:470 of 7-formyldehydrohernangerine 30:589 of 7-formyldehydronornantenine 30:589 of 7-formyldehydroovigerine
218
30:589 of 7-hydroxy-6-methoxy- 1methylisoquinoline 30:589 of 7-oxohernagine 30:590 of 9-methoxycamptothecine 5:84 of Acalycgorgia 5:368,369 of alga 5:342,346 of anacardic acids 30:156 of ansamycin 23:96 of Antiaris toxicaria (Moraceae) 28:220 ofantiarone I 28:227 ofantiarone J 28:220 ofantiarone K 28:220 ofantiarone L 28:220 ofartocarpus flavonoids 28:220 ofartonin A 28:220 ofartonin B 28:220 of artonin E 28:217,227,220 ofartonin H 28:220 ofaulacocarpin A 23:797 ofaulacocarpin B 23:797 of aulacocarpinolide 23:797 ofbetulinic acid 28:17,40 ofbicyclic phloeodictine B 28:688 ofbipinnatins 23:177 ofbroussoflavonol B 28:227 ofbroussoflavonol C 28:227 of camptotheeine 5:84 of celastroloids 23:649 of cembranes 23:180 of cembrones 23" 180 of chaparrin 23:299 of coclenterate 5:342 of cucurbitacin B 28:65 of curcumenes 23:180 of cyclic peptides 4:101,102 of cycloheterophyllin 28:220 of defensins 23:346 of dehydrobruceantin 23:285, 308,313 of dehydrobruceantinol 23:308,313 of doxorubicin 23:299 of eurycomalactone 23:301 of flavonoids 27:927 ofgalanal A 23:801 ofgalanal B 23:801
ofgancaonin R 28:227 of glucarubolone 23:299 ofglyasperin A 28:227 of glycyrol 28:227 ofguaianolides 23:180 of hernandonine 30:589 of hemanymphine 30:589 of heterophyllin 28:220 of holacanthone 23:299,301 ofindaquassin-X 23:296,299 ofinumakilactone A 28:468 ofinumakilactone B 28:468 ofkallilolides 23:180 ofkazinol B 28:227 of Licania genus 28:65 ofLicania heteromorpha 28:65 ofLicania michauxii 28:65 oflicochalcone B 28:227 of licoricidin 28:227 of longilactone 23:301 ofMaytenus amazonica 30:691 of mollusk 5:342 of momsin 28:227 ofnagilactone A 28:468 ofnagilactone B 28:468 ofnagilactone C 28:468 ofnagilactone D 28:468 ofnagilactone E 28:468 ofnagilactone F 28:468 ofnagilactone G 28:468 of N-hydroxyovigerine 30:589 of N-methylcorydaldine 30:589 of N-methylovigerine 30:590 of norartocarpetin 28:227 ofochraceolide A-E 23:698 of Penstemon campanulatus 24:837-838 ofpodolactone E 28:470 ofpseudopterolides 23:180 of samaderine-Y 23:299 of samaderine-Z 23:296,299 of sampsoniones 30:624 of sesquiterpenes 23:180 of sesquiterpenes alkaloids 23:660,679 of sponge 5:342-346,353 of thalifoline 30:590 of tunicate 5:342 of ulithiacyclamide 4:101
219
Cytotoxic agent 2:404,293-303,653; 19:601 ;26:760;30:310 D-aminoacyl-anthraquinone derivatives as 30:310 from Nerium oleander 9:293-303 savinin 13:653 Cytotoxic cardenolide 30:660,662 against KB cell line 30:660 from Crossopetalum gaumeri 30:660,662 Cytotoxic effects 23:531 of resveratrol 23:531 Cytotoxic flavonoids 27:925 Cytotoxic guanidine-alkaloids 25:706 Cytotoxic hydrophilic taxol derivatives 12:221 Cytotoxic peptides 4:83,110 Cytotoxic sesquiterpene alkaloids 23:679 Cytotoxic T cells (CTLS) 24:131; 30:778 Cytotoxic T lymphocytes 26:950 Cytotoxic triterpenes 23:694;30:690 Cytotoxic value 27:930 of flavonoids 27:930 of vinblastine 27:782 Cytotoxicity 5:388;21:134,136,150, 174,257,259,260,262,263,265,267, 269,270,271,273,274,284,311,364, 410,634,643,656,661,690,704,744; 23:96,97,187,218,238,249,250,253, 255,272,274,277,290,292,299,308, 317,701,274 ;24:294,352,740,867; 26:212-213,1185 ;27:94,924,926; 28:118,121 ;30:27,59,226,560,588, 593,596,690 against cancer cell lines 30:588 against marine lymphoma 23:187 against Meth-A 30:59 against uterine carcinoma 30:596 bioassay of 24:867 in COLO-205 (colon carcinoma) 30:690 in KB nasopharynx carcinoma 30:690 of 4'-demethyldeoxypodophyllotoxin 26:213
of (-)-6'-hydroxyyatein 26:212 of (-)-hernone 26:212 of (-)-nymphone 26:212 of (-)-yatein 26:213 of[3-alaninookadaic acid 5:388 of 13-amyrin 23:535 of 8-aminovalcrookadaic acid 5:388 of 7-aminobutyrokadaic acid 5:388 of [3-apopicropodophyllin 26:213 of 4-0-butanoyl-4'-demethyl podo-phyllotoxin 24:740,741 of 5-methoxydehydropodophyllotoxin 26:212 of ailantinol A 23:317 of amarolide 23:299,317 of 3-aminoflavones 27:926 ofamphidinolide B 5:396 of benzopentathiepins 23:238 ofbripiodionen 28:117,118 ofbruceanol C 23:288 ofbruceanol D 23:290,292 ofbruceanol E 23:290,292 of bruceanol F 23:290,292 ofbruceoside-A 23:317 of catechins 27:924 of cephalotaxus alkaloids 24:294 of chaparrin 23:299 of cholistane-3/~,5a,6p-triols 24:352 ofcystodytin A 23:272 ofcystodytin B 23:272 ofcystodytin C 23:272 of cystodytin J 23:272 of dehydro-[3-peltatin methyl ether 26:212 of dehydro-bruceantarin 23:308 of dehydro-bruceantin 23:308 of dehydro-bruceantinol 23:308 of dehydrokuanoniamine B 23:272 of dehydropodophyllotoxin 26:212 of deoxydehydropodophyllotoxin 26:213 of deoxypicropodophyllin 26:213
220
of dercitamide 23:274 of diplamine 23:272 of doxorubicin 23:299 of dysodanthin A 26:212 of dysodanthin B 26:212 of ecteinascidins 23:253,255 of equisetin 28:121 of Etoposide 26:213 of eurycomalactone 23:301 of fatty acid derivatives 23:218 of flavonoids on cancer cell line 27:893 of Ganoderman lucidum 30:59 of glaucarubolone 23:299 ofglycookadaic acid 5:384,385 ofhalichondrin B 5:378,380 ofhalichondrin C 5:380 of holacanthone 23:299 ofhomohalichondrin A 5:380 ofhomohalichondrin B 5:380 of indaquassin B 23:299 of isodeoxypodophyllotoxin 26:213 of isoquinoline alkaloids 30:588 of isoquinolines 30:588 ofkuanoniamine A 23:272 of lamellarins 23:242,245,249, 25O oflignan constituents 30:588 of longilactone 23:301 of macbecin I 23:97 of maytenfolone-A 30:690 of mecbocin I 23:97 of megaphone acetate 26:212 of naphthomycin A 23:66,96 of norhalichondrin A 5:378,380, 383,384 ofokadaic acid 5:384,385,389 of pantherinine 23:272 of penazetidine A 23:194 of quassinoids 23:285-333 of quinones 23:537 ofsamaderine X 23:288,299 ofshermilamine B 23:272 of shinjulactone C 23:317 oftaurookadaic acid 5:388 of theonellamides 26:1185 of mmour necrosis factor 5:387 of varamine A 23:272
of vatdiospyroidol 23:535 of voramine A 23:272 of yadanzioside 23:317 role ofheverlines A-C 30:596 to EL4 cells 30:27 Cytotoxicity assay 21:641 ;30:593 against JB6 cells 30:593 Cytotoxin agents 24:1055,1085 Cytotrienin 23:54 Cytotstatic activity 25:433,434 of Meth A tumor cell antigen 25:444 Cytovaricin 5:607 Cyttaria harioti 5:278;23:127 Czapek-Dox medium 25:154
l(x,25(OH)2D analogue 30:497 in human osteosarcoma 30:497 2D INADEQUATE spectra 9:143-146 1D INADEQUATE spectra 9:145 D-(-)-DIPT 19:490 D-(+)-DIPT 19:445,480,490 D:A-friedo-olean-3,21-dione 7:147,148 D:A-friedo-oleananes 7:150-152 biogenesis of 7:150-152 from Kokoona zeylanica 7:147149 D:B-friedo-oleanane 7:150 D:C-Friedooleanane 22:101 Dl-agonists 21:58 Dl-antagonists 21:68 D ~-receptor 21:18 24-epi-D2 30:490 synthesis of 30:490 1ct,25(OH)zD2 30:494,495 binding affinity of 30:494 bone resorbing activity of 30:495 calcemic effect of 30:495 D2-agonists 21:58 D2-antagonists 21:68 let,25(OH)zD3 30:484,494,495,500 analogues of 30:484 binding affinity of 30:494 bone resorbing activity of 30:495 calcemic activity of 30:484,495 effect on bone maturation 30:484 effect on calcium metabolism
221
regulation 30:484 effect on immune responsiveness 30:484 effect on malignant cell differentiation 30:484 in multifunctional biological responses 30:484 pharmacokinetics parameters of 30:500 use in cancers 30:484 use in immune disorders 30:484 use in psoriasis 30:484 1,25(OH)2D3 calf thymus receptor 30:496 competitive binding to 30:496 lct,25(OH)2D3 metabolites 30:495 D-3-(3,5-Dihydrophenyl) alanine 25:824 D3-receptor 21:18 ltx,25(OH)2D4 30:495,499,500,501,504 bone resorbing activity of 30:495 calcemic effect of 30:495 effect on animal model with osteoporosis 30:499 in rat 30:504 metabolic pathway of 30:504 pharmacokinetics parameters of 30:500 l(x,25(OH)2D4 activity 30:497 affinity of 30:497 bone mobilization of 30:497 on calcium transport 30:497 lo~,25(OH)2D4 drug 30:503 for immune disorders 30:503 for osteoporosis 30:503 for skin diseases 30:503 24-epi-D6 30:490 synthesis of 30:490 D-arabino-hex-2-ulosonate 20:857,859 D-arabino-hex-2-ulosonate sodium salt monohydrates 20:859 (DBU) Diazabicyclo[5.4.0]undec-7-ene 6:126; 127;13:424,425 D-arabitol 9:288 Dacrydium cuprassinum 3:117;13:1922 Dacrydium intermedium 20:619
Dacryhainansterone 29:19 as synthetic ecdysteroid analogues 29:19 Dactomelynes 19:411 Dactylicapnos torulosa 27:177 Dactylocyclines A 29:315 from Dactylosporangium strain ATCC 53693 29:315 stereochemistry of 29:315 sugar moieties of 29:315 Dactylol 3:91-93 synthesis of 3:91-93 from Aplysia dactylomela 6:35 relation to poitediol 6:35 synthesis of 6:36,37 (+)-Dactylol 6:37 cyclopropanone sliding reaction in 6:37 from (+)-africanol 6:37 from tricarbocyclic epoxide 6:37 Dactylomelol 17:8 Dactylopius coccus 20:734 Dactylospongia elegans 25:694 (-)-Dactylosponol 15:297 (-)-Dactylospontriol 15:297 Dactylosporangium ATCC 53693 29:315 Dactylynes 19:411 (-)-Dactylynes 19:411 Dacus cucumis 5:225 2,5-dimethyl-3-, 6-dimetyl pyrazines of 5:225 Dacus cucurbitae 5:225 2,5-dimethyl-3-methylp yrazines of 5:225 methylpyrazines of 5:222 Dacus dorsalis 5:222 2,5-dimethyl-3-methylp yrazines of 5:222 Dacus occfipitalis 5:222,223 2,5-dimethyl-3-ethylpyrazines of 5:222,223 Dacus oleae 4:571,222;14:521,19:131 DAG (diacylglycerol) 27:827-829 DAGO 30:801,802 inhibitory effects of 30:801 DAH 30:444,448,473 precursor of 30:444 stereocontrolled total synthesis of
222
30:473 synthesis of 30:448 4-epi-DAH acetylated esters 30:467 DAH ammonium salt 30:455 by spiroketal glycosides 30:455 Dahlia spp. 29:580 DAHP (3-deoxy-D-arabinoheptulosonate 7-phosphate) 11:183,184;30:420,431,472 in multienzyme system 30:431 structure of 30:420 synthesis of 30:472 DAHP synthetase plasmid 30:431 Daidzein 22:446 Daizein 26:751 Dakaira subovoidea 25:831 ;28:620 6H-anthra[ 1,9-bc] thiophene derivatives of 28:620 Dakin reaction 9:341 (D-Ala,des-Gly2)DYN-A-( 1-11)-NH2 30:809 activity in functional bioassay 30:809 analytical properties of 30:809 Dalbergia hupeana 25:93 Dalbergia parviflora 25:162 Dalbergia stipulacea 29:772 Daldinia concentrica 26:470 Dalea filiciformis 29:581 Daleformis (pterocarpinoid phytoalexin) 29:581 effects on ECE 29:581 from Dalea filiciformis (Fabaceae) 29:581 Daliocarpus dentatus 26:229 (-)-liriorinol B from 26:229 (+)-medioresinol from 26:229 (+)-pinoresinol from 26:229 Dalton's lymphoma ascites 26:303 Damacus carota 25:377,669 Damaliscus dorcas 19:122 Damarane 25:50 ct-Damascenone 13:328 T-Damascenone 14:425 from Rosa damascena 14:425 [3-Damascenone 14:430,431 fromRosa damascena 14:425 from safronitrile 14:430,431
from thujone 14:431,432 synthesis of 14:430,431 Damascones (rose oil ketones) 14:425-431 synthesis of 14:425-431 Damavaricin 21:430;23:54 Damavaricin D 21:435 Damavaricin Fc 23:97 Damiana 13:660 Damirones 25:707 23-(Z)-3,25-dioxo-25-nor-Dammara20,24-diene 30:658 HMBC spectrum of 30:658 Dammaradienol (dammara-20,24-dien313-ol) 29:586 effects on CHY 29:586 Dammarane 22:95;23:692 Dammarane derivatives 2:91-93 Dammarane saponins 24:144,146 Dammarane triterpenoids 2:91-93 Dammarane type saponins 21:651; 23:503 Dammarenediol-I 23:546 Damnacanthal 25:546;26:673,806 c~-Damscone 14:425 fromRosa damascena 14:425 Damsin 1:546 Danaidone 8:223 from Danaus gilippus 8:223 Danaus gilippus 8:223 danaidone from 8:223 Danaus plexippus 21:107 D-and L-2,4-Di-O-benzyl-myo-inositol 18:427 Dandrolasin 17:13 Danishefsky synthesis 12:12,13,15 of mitomycins 13:443 ofavermectin A~a 12:12,13,15 Danishefsky's diene 1:460,474;4:122, 130,132;8:207;13:565;14:18, 636-638;16:474,496,654 Danishefsky's KDO synthesis 30:461 Danishefsky's pyran synthesis 1:460, 407 Danshenol A 22:175 Danshenol B 22:175 Danshensuan B 26:235 3-Dansylamino piperidone 9:549 Dansylation 9:547,549
223
Dansyl-CaM fluorescence 25:544 Dapetes 198 Daphna genkwa 13:660 yuanhuacine from 13:660 Daphnandrine 26:824,826 Daphnane 12:246;25:246 Daphne cannabina 27:833 activator from 27:833 Daphne mezereum 20:22;27:833 activator from 27:833 Daphne odorata 26:465 Daphnetin 7:224;27:847 Daphnetoxin 20:22 Daphniphyllium alkaloid 16:441 synthesis of 16:441 Daphnoretin 25:545 Daphnoretin (4) 27:847 D-arabinose 30:452 D-arabinose derivatives 30:434 methyl dichloroacetate 30:434 D-arabinose-5-phosphate 30:429 irreversible aldol reaction of 30:429 Dartiscin 5:682 Darzens reaction 17:612 Darzens-Nenitzescu condensation 19:235 DAST 19:341 Dasyanthogenin 25:199 Dasycarpidone 1:34,56-58 Dasytricha 2:294 Datisca cannabina 5:678,682 Datiscanin 5:682 Datiscetin 5:678 Datiscoside 5:682 Datumetilin 20:181 Datura aurea 22:742 Datura brugmansia 22:734 Datura candida 22:742 Daturafastuosa L. 22:519,742 for epilepsy 22:519,742 Datura innoxia 11:204;22:742 Datura metel L. 22:519 for epilepsy 22:519 Datura stramonium 20:135;22:742 Datura tatura 20:194 daturataturin A and B from 20:194 Datura. 17:395;21:104,488
Daturadiol 7:164,166 Daturalactone A 20:194,242,246 Daturalactone B 20:194,223,241,246 Daturalactone C 20:180,241 Daturilin 20:181 Dauben-Mincho oxidation 21:714 Daucane diol 21:232 (+)-Daucene 14:356 (-)-Daucene 5:732,734,226 (-)-Daucol 14:356 Daucol 5:721,725,730-732,736,737 Daucus 29:579 Daucus carota W. 5:721,730;22:519; 27:686;29:592 as anticonvulsant agent 22:519 for epilepsy 22:519 Daucus spp. 27:686 Daucyl-d,/-alaninate hydrobromide 5:721 Daunomycin 1:498,371-319,412,474, 475,493;14:474,475;26:802 Daunomycinone 1:500-502;4:321,322, 349;14:24-42 biosynthesis of 11:123 from aklavinone 11:123 synthesis from amino acids 4:345-349 synthesis from hydroxy acids 4:345-349 synthesis of 1:500-502;4:321, 322,349;14:24-42 Daunorubicin 4:317,318,355;14:3; 20:458;21:157,163,165-168,176 L-Daunosamine 1:510-513 synthesis of 1:510-513 3-epi-Daunosamine 4:149 synthesis of 4:149 Daunosamine 4:150;14:4;21:168 synthesis of 4:150 Daunosamine analogues 4:240,241 of adenine 4:240,241 of cytosine 4:240,241 of puromycin 240,241 of thymine 4:240,241 Daurinol 17:335 synthesis of 17:335 Daurisoline 21:72 Davana ether 9:533
224 Davanone 3:58,217,218;7:217; 9:531-533;27:592 Davidiol B&D 26:463,564 Davidsonia pruriens 29:588 Davuriciin D~ 23:404 1,3-Davuriciin T1 23:404 Dawodensin A 15:117,124,131,171 DBU 22:209 DCC-HOSu procedure 6:407,409 2D-COLOC 9:147,151,152 3,5-DCQA 25:942,941 1,5-DCQA 25:944 3,4-3,5-4,5-DCQAs 25:940 1,5-3,4-and 4,5-DCQAs 25:941 DDPM 21:674 DDQ (2,3-dichloro-4,5-dicyanobenzoquinone) 11:156,165;21:735 DDQ oxidation 21:388 DDT 21:110 De novo synthesis 25:128,129,294,300, 329,401,659,661,662 De novo-biosynthesis 25:374 4-Deacetoxy T-2 toxin 9:210 6-Deacetoxy- 14,15-deepoxy-xeniculin 29:103 9-Deacetoxy- 14,15-deepoxyxeniculin 5:369,370 Deacetoxy-3'-chloro-2'-hydroxyarguticinin 5:207 IH-NMR spectrum of 5:207 Deacetoxy-3-chloro-2-hydroxyarguticinin 9:66 12-epi-12-Deacetoxyaplysillin 17:12 Deacetoxycephalosporin C 11:211,212 C-3-hydroxylation of 11:211,212 Deacetoxylakuammiline 9:194,195 10-Deacetyl baccatin III 12:217;25:245 10-Deacetyl cephalomannine 25:245 2 5-Deacetyl-2 5-ep i-hy drox y-rifamycin S 23:56 Deacetyl-8-cyclotulipinolide 27:557 Na-Deacetylaspidospermatine 1:40 Deacetylation 1:10 10-Deacetylbaccatin III 11:3,5,61; 23:490 from Taxus baccata 11:61 6~-Deacetyl-baogongteng A 21:751 28-Deacetylbelamcandal 27:835 10-Deacetyldaphylloside 7:469,470
Deacetyldeformoakuammiline 9:194,195 N-Deacetylisoretuline 1:38,39, 9:183,188 Deacetyllutessine 26:610 Na-Deacetyl-Na methylstrychnobrasiline 26:1064,1066 Deacetylretuline 1:38,39 6-Deacetylsandrasin A 23:624,625 ~H-NMR data of 23:625 ~3C-NMR data of 23:625 3,4-Deacetylsoipecoside 26:115 Na -Deacetylstrychnobrasiline 26:1064-1066 10-Deacetyltaxol 11:61;20:81 ;25:245 7-epi-l O-Deacetyltaxol 20:81 Deacetylvindoline hydrazide 14:808, 863 coupling of 14:808 with 20[3-dihydrocleavamine 14:808 9-Deacetylxenicin 5:370 Deacetyl-[3-cyclo-pyrethrosin 27:555 Deacylgymnemic acid 18:655,656,661 DEAE-Cellulose chromatography 2:392,393,394 N-Dealkylation 27:754 and electron transfer 27:754 O-Dealkylation 27:754 and electron transfer 27:754 Deaminated Neu5Ac analogues 30:427 preparation of 30:427 Deamination 1:681 of (R)-2-aminohexadecanoic acid 1:681 Dean-Stark water separator 19:219 Deazaflavin F420 20:840 Debaryomyces castelli 5:283 Debaryomyces hansenii 5:282,283 Debaryomyces kloeckeri 5:283 Debaryomyces phaffi 5:283 Debaryomyces subglobosus 5:283 Debenzylation 11:253,254;19:110,115; 30:441 Debenzylidenation 12:347 by Hanessian procedure 12:347 Deboronation 11:412,413 Debregeasia salicifolia 29:588 Debromination 4:336,337
225 Debromoaplysiatoxin 18:295,297, 19:219 Debromoeudistomin K 25:816,817 Debromohymemialdisine 25:791 5-Debromooroidin 21:270 (2E,4Z)-2,4-Decadienal 10:151 (2E,4E)-2,4-Decadienal 10:151,155 trans-Decahydro-5,8a-dimethyl- 1,6naphthalenedione derivatives 10:461 Decahydroisoquinolines 12:446 (+)-trans-Decahydroquinoline 219A 19:4,7 Decahydroquinoline-type dartpoison frog synthesis 29:419 by Stereodivergent process 29:419 n-Decane 21:600 ),-Decanoiactone 22:511,537 Decanol 21:589 8-Decanolactone 21:197;22:511,537 (R)-y-Decanolide 13:308,309,315,329 (S)-y-Decanolide 13:311,312 Decanolide 13:312,315 ~/-Decanolide 13:32,310,313,315,328, 332 6-Decapeptides 9:487-489 Decaprenoxanthin 7:355 ;20:596,597 absolute configuration of 7:355; 20:596,597 from Cellulomonas dehydrogenans 7:357 Decarboalkoxylative cyclization 14:720-722 alkaline 14:720-722 indolo-[2,3-c~] quinolizidines from 14:720-722 stereochemical course of 14:720-722 Decarbomethoxy- 15,20,16,17-tetrahydrosecodine 5:124 16-Decarbomethoxy- 19',20'-20'-epivoacamine 5:128 16-Decarbomethoxy- 19',20'dihydrovoacamine 5:124 16'-Decarbomethoxy-20'-deoxyvinblastine 4:30,31
Decarbomethoxycatharanthine 14:870,871 Decarbomethoxydeacetylvinblastine monohydrazide 14:863 from deacetylvindoline hydrazide 14:863 velbanamine from 14:863 Decarbomethoxylation 3:473 with MgC12/DMSO 3:473 with CaClz/DMSO 3:475 16R-Decarbomethoxytacamine 5:125 16S-Decarbomethoxytacamine 5:126 16R, 16'-Decarbomethoxytetrahydrosecamine 5:141,142 16S, 16'-Decarbomethoxytetrahydrosecamine 5:142,143 16-Decarbomethoxyvoacamine 5:125 Decarbonylation 3:308,309 Rh (I)-catalysed 3:308,309 with Wilkinson's catalyst 11:263 with chloro-tris-(triphenyphosphine) rhodium 5:802 Decarbonylation -iminium ion cyclization 4:38,39 Decarboxylase 8:298;21:106 Decarboxylation 16:371 of [3-keto ester 16:371 of anthrones 11:121 of 2-methyl-3-buten-2-yl acetate 11:130 Pd-catalyzed 11:143,144 of vinylogous [3-keto acid 14:678-681 Decarboxylative condensation 11:195 8-Decen-2-1actone 22:511,537 10-Dechlorodysideathiazole 25:890 10-Dechloro-N-methyldysideathiazole 25:890 11-Dechlororebeccamycin 12:366,368 from Saccharothrix aerocolonigenes 12:366,368 L-Decilonitre 19:118 Decilorubicin 19:118 Decinnamoyl taxinine J 11:5 Decipiances 15:263-269 Decitol 4:183 Decoctions 30:704,691 for medicinal purposes 30:704
226
Deconjugation 1:464,465 Deconjugative alkylation 4:38 Decriamide 25:893 Decumbenine 21: 733 Decumbenine B 21:733,734 biological activity of 21:736 synthesis of 21:735 Decumbenine C 21:733,734 Decumbesterone A 25:59 Decursin 23:351 Decyanation 6:431-433 Dedrogyl 9:513 Deepoxyneoxanthin 6:136,143,144 DEET 21:611 20-D eethyl-20- epivinc adifformine 19:109,112 20-Deethyl-3-oxo-20-epivincadifformine 19:110-111 20-Deethyl-3-oxotabersonine 19:112 20-Deethyl-3-oxovincadifformine 19:110-111 20-Deethyl-3-thiooxotabersonine 19:112 16-Deethylapovincamine 19:112 Deethylibophyllidine 9:190 20-Deethyltabersonine 19:112 20-Deethylvincadifformine 19:109,111112 Defence gene activation 25:396 Defence mechanism 23:180 against predation 23:180 Defense proteins 25:370 serine proteinase inhibitor I as 25:370 Defensins 22:75,83 Defluorination 5:453,455,477 of 2-fluroestradiol 5:477,453,455 Degalactosylation 7:55 Deglucosylation 26:110,112 of 7-substituted bakankosine derivative 26:112 of secologanin 26:110 Degradation 9:31,32 of aureol 9:31,32 of enantio-sigmosceptrellin-A 9:28,29 ofgeraniol 7:104,105,116 of nerol 7:105 of c~-pinene 7:106
of S-HPOTE 27:71 of 13S-HPOTE 27:71 Degradation reaction 21:502 Deguelin 28:436 as complex I inhibitor 28:436, 437 Dehomologation 12:95 Dehydration 10:124 with Burgess reagent 10:124 of N-monosubsituted formamides 12:113 of phenyl sulfone derivative 30:486 Dehydrioiridodial 16:290 Dehydro 7- a-hydroxy-tomatidenole (DS-d) 25:318 Dehydroabietic acid 14:685,687-689 abietatriene-7-one from 14:685,687-689 Dehydro-[3-peltatin methyl ether 26:212 cytotoxicity of 26:212 10-Dehydro- 10-deacetyl- 11(15-1 )-abeo baccatin III 20:107 19,20-Dehydro- 10-methoxytalcarpine 13:388 14-Dehydro- 15-phenylsparteine 27:262 structure of 27:262 (+)- 14,15-Dehydro- 16-epi-vincamine 5:126 2-Dehydro- 17[~-isopropyl-2-phenylsparteine 27:264 25-epi-4-Deh ydro-2,3,25,27tetrahydrophysalin A 20:189 3-Dehydro-24-epi-teasterone 25:422, 423 3-Dehydro-24-epi-teasterone-reductase 25:422 2-Dehydro-24-norcholesterol 9:412 26-Dehydro-25-epiaplysterol 9:40 from Petrosia ficiformis 9:40 2-Dehydro-2-phenyl- 17[3methylsparteine 27:264 2-Dehydro- 2-phenylsparte ine 27:260,261 mesomeric form of 27:261 2-phenyl-2-dehydrosparteine salts of 27:260,261
227 9,11-Dehydro-3-deoxy-2-oxa-25hydroxy-vitamin-D3 9:515 9,11-Dehydro-3-deoxy-c~-nor-2-oxa-25hydroxy-vitamin D3 9:515 3-Dehydro-6-deoxoteasterone 25:415 Dehydro-6-hydroxymellein 25:498,499 Dehydro-9,10-aristoteline 9:172 Dehydroabietane 2:402,404 Dehydroabietic acid 15:173;29:99 activity in EBV assay system 29:99 from Rabdosia nervosa 15:173 (+)-Dehydroabietylamine 22:279 1,2-Dehydroacetylretuline 1:38,39 (-)-AS-Dehydroalbine 15:524 from Lupinus termis 15:524 18,19-Dehydro-alloaristoteline 11:319, 320 alloaristoteline from 11:319,320 Dehydroamino acids 16:410 (+)-Dehydroancistrocladine 20:419, 420,426 Dehydro-arachidonic acids 9:568 1,2-Dehydroaspidospermidine 2:370; 14:635,636 Dehydrobromination 11:341,342 Dehydrobruceantarin 23:308 cytotoxicity of 23:308 Dehydrobruceantin 7:374 Dehydrobruceantol 7:374 Dehydrobrucein-B 7:374 Dehydrobrusatol 23:295 (+)-Dehydrocaffeic acid dilactone 26:238 (-)-5,6-Dehydrocamphor 16:144 (+)-5,6-Dehydrocamphor 4:644 7-Dehydrocholesterin (chlolesterol) 9:510,511 7-Dehydrocholesterin reductase 9:512 7-Dehydrocholesterol 5:406 22-Dehydrocholesterol 9:47 7-Dehydrocholesterol (provitamin D3) 9:511,521 7-Dehydrocholesterol-reductase 9:511 18,19-Dehydrocobyrinic acid 9:601 Dehydroconiferyl alcohol 5:497;26:202 11-Dehydrocorticosterone 22:135 (-)-Dehydrocostus 14:368
Dehydrocostus lactone 1:556,559;29:89 activity in AM assay system 29:89 synthesis of 1:556,559 trans-Dehydrocrotonin 29:100 activity in CRG assay system 29:100 Dehydrocurdione 23:825 Dehydrocurvularin 11:193,194 by Alternaria cinerariae 11:193,194 Dehydrocyclospongia quinone-I 15:299 1,2-Dehydrodeacetyl retuline 9:195 1,2,3,4-Dehydrodeoxypodophyllotoxin 30:592 as EBV inhibitor 30:592 11,13-Dehydrodesacetyl matricarin 27:580 Dehydrodesoxypodophyllotoxin 18:553,555 1,2,3,4-Dehydrode soxypodophyl lotoxin 18:557,561 3,4-Dehydrodesoxypodophyllotoxin 18:588 Dehydrodicatechin B4 27:778 from (+)-catechin 27:778 Dehydrodiconiferyl alcohol 5:465,467, 497 Dehydrodigalloyl group 23:397,399 in oligomers 23:399 Dehydroeburiconic acid 25:57 3-Dehydroecdysone 19:634 24-Dehydroechinoside A 7:270 from Actinopyga agassizi 7:270 Dehydroepiandrosterone (DHEA) 24:351-398;25:419 Dehydroepijuvabione 22:387 (-)-10,11-Dehydroepingaione 15:237 5-Dehydroepisterol 25:415 Dehydroerucin 215:481 19,20-Dehydroervatamine 5:124 5,6-Dehydroeurycomalactone 23:301 Dehydrofalcarinone 7:202,222 2-Dehydroferruginol 2:402 Dehydrogeissoschizine 15:486-488 Dehydrogenase enzymes 22:4 Dehydrogenation 2:3,4 in CI(NO) mass spectra 2:3,4 of amines 4:54
228 with CMD 4:85 with DDQ 1:8,9,59 with other oxidants 4:85 with palladium black catalyzed 14:763 with p-toluene sulfinyl chloride 4:54 with selenium reagents 14:440 with sulfur catalysis 14:763 13,18-Dehydroglaucarubinone 7:381 Dehydroglyasperin C 28:228 biological activity of 28:228 22-Dehydrohalitylosides D,D 7:298 from Sphaerodiscus placenta 7:298 Dehydrohernandaline 30:563,594 as platelet aggregation inhibitor 30:594 Dehydroipomeamarone 15:249 Dehydroiridodial 3:136;16:290 from Actinidia polygama Miq. 16:290 Dehydrojuvabione 25:546 5,6-Dehydrokawain 23:808 Dehydroleucodin 29:90 activity in COX assay system 29:90 activity in NFkB assay system 29:90 Dehydroleutodin 27:580 Dehydrologanin 16:294 (+)-5,6-Dehydrolupanine 15:523 from Thermopsis chinensis 15:523 11,12-Dehydromakomakine 11:281,282 (+)-makomakine from 11:281, 282 Dehydromatricaria ester 7:202,203,221 Dehydrometenolic acid 25:57 Dehydromonocrotaline 22:13 Dehydromoracin C 28:210 from moraceous plants 28:210 (-)-ALDehydromultiflorine 15:525 from Lupinus termis 15:525 R-(+)-10,11-Dehydromyoporene 15:229 (-)-Dehydromyoporone 15:229 (-)-10,11-Dehydrongaione 15:237 (E)-8-epi-2,3-Dehydrononactate 18:236
(6S,8R)-(E)-2,3-Dehydrononactate 18:237 Dehydronorglaucine 16:508 Dehydroophioxanthin 15:100;30:526, 527 Dehydrooxoperezinone 5:771,773 Dehydropachymic acid 25:57 Dehydropeptidase- 1 (DHP- 1) 12:145 Dehydropipemonaline 21:379,382 Dehydropodophyllotoxin 18:554; 26:212 cytotoxicity of 26:212 1,2,3,4-Dehydropodophyllotoxin 30:568,592 12-Dehydroporson 26:895 Dehydropreakuammicine 1:31 (-)-20S- 1,2-Dehydropseudoaspidospermidine 5:124 (+)-20R- 1,2-Dehydropseudoaspidospermidine 5:124 3-Dehydroquinate 11:184-186 from 3-deoxy-D-arabinoheptulosonate 7-phosphate 11:184-186 3-Dehydroquinate 23:740 3-Dehydroquinate synthase 11:184,219 Dehydroquinic acid 25:928 1,2-Dehydroreticuline 18:53 1,2-Dehydroreticuline reductase 18:53 1,2-Dehydroreticulinium ion 18:53 Dehydroretronecine 22:13 6,7-Dehydroroyleanone 15:173 from Rabdosia lophanthoides var. gerardiana 15:173 from Rabdosia stracheyi 15:175 Dehydrosalviarin 26:868 Dehydrosalvilimbinol 20:683 from Salvia limbata 20:683 2,3-Dehydrosalvipisone 20:712;26:402 Dehydrosaponin I 25:105 Dehydroschisandrol A 26:245 as PAF-induced inhibitor 26:245 6,7-Dehydroschisandrol A 26:247 Dehydroscoulerine 11:204,205 by S-tetrahydroprotoberberine oxidase 11:204 from scoulerine 11:204,205
229 Dehydrosecodine 14:832 epipandoline from 14:832 pandoline from 14:832 Dehydroshikimate 5:124;11:184,185 3-Dehydroshikimic acid 25:928 Dehydroshowdomycin 10:393 by Wittig reaction 10:393 synthesis of 10:393 Dehydrosoyasaponin I Dehydrosoyasaponin I 21:659;25:97, 104,115,116,118,120 22-Dehydrosterols 21:309 25-Dehydrostichlorogenol 7:272 Dehydrosulfinylation 6:342 19,20-Dehydrotalcarpine 13:411, 427,428 synthesis of 13:411,427,428 3-Dehydroteasteron 18:500;25:415, 422,423 from Distylium racemosum 18:500 from Triticum aestivum 18:500 synthesis of 18:512,513 14,15-Dehydrotetrastachynine 5:129 Dehydrotumulosic acid 25:57 dehydropachymic acid 25:57 16a-hydroxtrametenolic 25:57 pachymic acid 25:57 Dehydroxdycapuvosine 5:124 4'-Dehydroxy-4'-flourotebquine 25:344 Dehydroxyisocapuvosine 5:124 4'-Dehydroxytebuquine 25:344 19,20-Dehydroyohimbine 3:412,415 synthesis of 3:412,415 Dehydroyohimbines 3:399,411,412 Dehydrozaluzanin C 26:371,808,809 Dehydrozingerone 23:798 y-Dehydro-c~-amino acid 11:471,472 synthesis of 11:471,472 1,4-Dehydro-13-1actam 12:159,160,167, 172,173 3-Dehydo-6-deoxoteasterone 25:415 19,20-Dehyrocivetone 8:224 Deinbollia borbonica 22:519 for epilepsy and convulsions 22:519 for convulsions 22:519 for epilepsy 22:519 Deisopropylidenation 4:200,201
Deketalization 14:678,679 Deklamin 9:513 DEL 30:800,814 antinociceptive effects of 30:800 resistance to enzymatic degradation 30:814 DELC 30:816 structural modifications of 30:816 DEL C analogues 30:815 antinociceptive action of 30:815 DEL C peptides 30:814 Delayed COSY spectra 9:151,152 Delayed-type allergy suppressant activity 25:46 ofserotonin agonists 25:46 Delesseria sanguinea 4:712 Delocalised allylic cation 30:547 formation of 30:547 Delonix regia 29:604 Delphinidin (anthocyanidin) 5:646; 23:536,551,742,748 ;29: 582,584 effects on LELA 29:584 effects on MMP 29:582 Delphinin chloride 20:738 Delphinium 20:19;26:868,869,871 Delphinium cardiopetalum 26:868 Delphinium consolida 22:519 Delphinium denudatum Wall 22:519 for epilepsy 22:519 Delta opioid receptor 30:799,800 role in analgesia 30:799 Delta receptors 22:24 Deltorphin B 30:801,804,807,817 activity in RJ bioassay 30:807 agonist activity of 30:817 antinociception activity of 30:804 8-selective opioid agonist 30:817 Deltorphin C 30:813 pharmacological activity of 30:813 Deltorphin II 30:810 activity in Tail flick test 30:810 Deltorphins 30:799,801,814 as 8 agonist 30:799 from frog skin 30:801 ct-Demascone 19:137
230 DeMayo reaction 3:74,75,102,103 (+)-4-Demercuration 1:671,672 with sodium borohydride 1:671,672 Demercuration 1:671,672 with sodium borohydride 1:671,672 4 '- O-Demethyldehdropodophyllotoxin 26:227 antifungal activity of 26:22 6-Demethoxy acronycine 20:795 4-Demethoxy anthracyclinones 14:10 4-Demethoxy daunomycinone 14:17 Na-Demethoxy- 11-methoxy-(19Rhydroxy-gelselselegine 15:513 11-Demethoxy- 12-hydroxymyrtoidine 26:1053 4-Demethoxy- 1-O-methyl daunomycinone 14:5 4 '-D emethoxy-3 ',4 '-methylenedioxymethylrocaglate 26:203 4 '-D emethoxy- 3 ',4 '-methylenedioxy rocaglaol 26:203 4-Demethoxy-6-desoxyadriamycinones 14:8 4-Demethoxy-7-deoxydaunomycinone 1:507,508 7-Demethoxy-7-deoxydaunomycinone 4:342,343 4-Demethoxy-7- O-methyl daunomycinone 14:5 4-Demethoxy-9-deacetyl-9-(hydroxymethyl) daunomycinone 14:12 4-Demethoxyadriamycin 4:317 (+)-Demethoxyaspidospermine 19:143 16'-Demethoxycarbonyl-16'-epideoxyvinblastine 14:850-852 synthesis of 14:850-852 Demethoxycarbonylation 10:308,309 by Welch procedure 10:308,309 Demethoxycarbonyldeoxyvinblastine 5:183,184 synthesis of 5:183,184 12-Demethoxycylindrocarpidine 5:124 4-Demethoxydaunomycin 1:501,505510;4:319,320 synthesis of 1:501,505510;4:319,320,323,324,334, 335
Demethoxydaunomycinone 4:319,320 synthesis of 4:319,320 Demethoxydeoxodihydrocolchicine 3:290 synthesis of 3:290 3-Demethoxyerythratidinone 3:479 synthesis of 3:479 (+)-3-Demethoxyerythratidinone 8:270272 synthesis of 8:270-272 1-Demethoxyfeudomycinone 4:346,347 enantioselective synthesis of 4:346,347 Na-Demethoxyhumantenirine 15:494,495 10-Demethoxykopsidasinine 5:5254;9:186-189 Demethoxykopsidasinine 9:188,189 11-Demethoxymyrtoidine 26:1053 (-)- 12-Demethoxy-N(1)-acetylcyclindrocarine 19:112 12-Demethoxy-N(1)-acetylcyclindrocarine 19:115 Na-Demethoxyrankinidine 15:496 from Gelsemium elegans 15:496 12-Demethoxytabernulosine 5:127 Demethoxyyangonin 22:529,541 4'-Demethycpipodophyllotoxin 26:193 (-)-Nb-Demethyl alstogustine N-oxide 9:190 7-O-Demethyl chelerythrine 14:783 7-O-Demethyl dihydrochelerythrine 14:780,781 Demethyl frutescin 9:317 7-O-Demethyl oxychelerythrine 14:783,784 7,8-demethylene sanguinarine from 14:783,784 N-methyl decarine from 14:783,784 Demethyl zeylasteone 7:147,148 Demethyl zeylasteral 7:147-149 N-Demethyl-16-epi-accedine 5:127 Demethyl-2',4'-bis-O-(2-methoxy ethoxy methyl)-7-con-O-3'-N-methylnogarol 14:88 3'-N-Demethyl-2'-4-b is-O-(2-me tho xy ethoxymethyl)-7,8 dihydronogarene 14:87
231 (-)-9-Demethyl-7,9-dimethoxynogarene 14:82 9-Demethyl-9-hydroxy-7-methoxynogarene 14:82 Nb-Demethylalstophylline oxindole 5:159-161;9:196,197 (+)-Demethylaspidospermidine 5:127 Demethylated gardenin A (5,6,7,8,3',4', 5'-nonahydroxyflavone) 29:572 effects on HIV- 1 protease 29:572 Demethylation 1:8,9 O-Demethylbuchenavianine 21:133,134 N4-Demethylcapuvosine 5:124 11-Demethylconoduramine 5:129 Demethylcryptoj aponol 20:666 from Salvia montbretii 20:666 4'-Demethyldeoxypodophyllotoxin 26:213 cytotoxicity of 26:213 4-Demethyldesoxypodophyllotoxin 5:480-484,488 Demethyldihydrokamebacetal A 15:135 (-)-Nb-Demethylechitamine 9:183,184 5-Demethylene bicyclomycin 12:75,76 synthesis of 12:75,76 7,8-Demethylene sanguinarine 14:783, 784 5-Demethylene-6-deoxy bicyclomycin 12:75,76 synthesis of 12:75,76 6,7-Demethylenedeoxypodophyllotoxin 30:568,592 as EBV inhibitor 30:592 Demethylenepodophyllotoxin dimethyl ether 18:597 3-Demethylgorgosterol 9:372 from Gorgoniaflabellum 9:37 from Gorgonia ventilina 9:37 9-O-Demethylhomolycorine 26:619 13-Demethylisodysidenin 25:889,890; 28:666 Demethylmoracin I 28:18 as aromatase inhibitor 28:17 Na-Demethyl-Na-formylleurosine 14:818,819 O-Demethylpalosine 5:127 5-O-Demethyl-paxanthonin 30:620 structure of 30:620
Demethylpeceyline 5:149-151 4'-Demethylpodophyllotoxin 5:475, 477,479,480-482,488,493 ;26:156, 157,192,210,214 N-Demethylrohitukine 3'-acetate 21 : 141 Demethylsonodione 30:570,589 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:589 high-resolution electron impact mass spectrometry (HREIMS) of 30:570 ~H-NMR spectrum of 30:570 IR spectrum of 30:570 molecular formula of 30:570 UV spectrum of 30:570 (___)-6-Demethylstatine 13:514 synthesis of 13:514 N4-Demethyltabernamine 5:123 N4-Demethylvoacamine 5:128 Demethylyatein 5:488;26:157 4'-Demethylyatein 26:192 Demethylzelasteral 5:744-746 Demethylzeylastrone 5:744-746 Demissidine 7:23;25:536 22R,25S-Demissidine 7:19-21 Demodex genus 28:410 Demospongic acid 25:721 Dendrilla cactos 23:246 Dendrimedric peptide 25:336 Dendrimeric multiple antigenic peptides 25:335 Dendroamides 25:716 Dendrobaena clujensis 30:828 from Lumbricidae family 30:828 Dendrobates alkaloids synthesis 29:433-436 aldehydes synthesis in 29:435 aldol-type cyclization reaction in 29:436 alkyl group installation in 29:43 decahydroquinoline type of 29:433 stereochemical course of 29:434 Dendrobates auratus 27:243 Dendrobates histrionicus 11:294 (+)-indolizidine from 11:294
232
Dendrobates pumilio 12:294;19:4; 27:242;29:439 panamanian population of 19:4 pumiliotoxin B from 12:294 Dendrobates speciosus 11:266;12:294 indolizidines from 11:266 N-oxides of allopumiliotoxin 267 A from 12:294 N-oxides of pumiliotoxin 323 A from 12:294 Dendrobates tricolor 12:294 pumiliotoxin 251 D from 12:294 Dendrobatid toxin 1:286,287 synthesis of 1:286,287 Dendrobatidae 11:244,294;12:294 (-)-Dendrobine 16:435 synthesis of 16:435 Dendrobium crepidatum 12:285 crepidamine from 12:285 crepidine from 12:285 dendrocrepine from 12:285 Dendrocotonus brevicomis 11:413 exo-brevicomin from 11:413 Dendrocrepine 12:277,285,286 Dendroctonus pseudotsugae 22:388 Dendrodoa grossularia 5:412;10:245; 23:257,260;28:633 dendrodoine from 28:633 Dendrodoine 5:412;23:257 cytotoxic activity of 5:412 Dendrodoris grandiflora 17:28 Dendrodoris limbata 17:28 Dendroibatidae 19:3 Dendroid-test method 13:233,234 Dendrolasin 1:666 cyclization of 1:666 Dendropanax trifidus 2:98-103 dendropanoxide from 2:98-103 Dendropanoxide 2:98-103,164,165 Dendrostilbella 21:233 Dendryphiella salina 10:152 Dendryphiellin A 10:149,152 Dendryphion sp. 27:871 Dennstaedtia hirsutu 26:111 Dennstaedtia scabra 26:722 De-N-protection 11:270 via hydrogenolysis 11:270 Densitometry 9:453
Dental surgery 30:192 use of non-steroidal antiinflammatory drugs (N SAIDs) 30:192 use of prostaglandin inhibitors 30:192 Dentatin A 7:232;27:551 Dentatin B 7:230 Denticulatin 5:211,212 Denticulatin A and B 17:24 antimicrobial activity of 17:24 Dentroctonus brevicomin 19:126 Denudatin 26:240 antifeeding activity of 8:160 as PAF-induced inhibitor 26:240 Denudatin B 26:233 De-O-acetylation 14:230,232 De-O-benzylation 12:37,38,52 Deoxdehydropodophyllotoxin 26:194 Deoxmannojirimycin 10:527 13-Deoxo- 13et-acetyloxy- 1-deoxy-nortaxine B 20:80 13-Deoxo- 13ot-acetyloxy- 1-deoxytaxine B 20:80 13-Deoxo-13c~-acetyloxytaxine B 20:80 6-Deoxo-24-epicastasterone 18:503,514 6-Deoxo-28-norcastasterone 18:507 9(R)-9-Deoxo-9-dimethyl-aminoerythromycin A 13:182 6-Deoxocastasteron 18:503 6-Deoxocastasterone 25:415,424 C6 oxidation of 25:415,424 11-Deoxoglycyrrhetinic acid 21:656 11-Deoxoglycyrrhetol 21:656 (-)-Deoxoprosopine 12:475 (+)-Deoxoprosopinine 13:482 Deoxosarcophines 21:280,281 Deoxoscalarin 17:10 6-Deoxoteasterone 25:415 3-Deoxotyphasterol 25:415 5-Deoxy analogue 27:842 of quercetin 27:842 11-Deoxy anthracyclinone 14:49 11-Deoxy daunomycinone 14:472 (-)-7-Deoxy daunomycinone 14:493, 494 synthesis of 14:493,494
233
Deoxy PDE-I 3:355 synthesis of 3:355 Deoxy PDE-II 3:355 synthesis of 3:355 Deoxy PTX 251H alkaloid 27:247-249 structure of 27:249 2-Deoxy [3-arabino pyranosyl cyanides 10:354 2-Deoxy [3-glucose 7:59 3-Deoxy- 1,2,5,6-di- O-isopropylidene-3C-methyl-c~-D-gluco furanose 10:435,436 3-Deoxy-l,2:5,6-di-O-isopropylideneD-xylo-hexofuranose 14:172 3-Deoxy-l,2:5,6-di-O-isopropylidene-otD-ribo-hexofuranose 14:154,155, 157,166-171 1'-Deoxy- 1'-fluoro-ABA 27:334 biological activity of 27:334 9,11-Deoxy- 11-methyl-prostaglandins 7:481 Deoxy- 15(15S')-20'-'-14:814,815 hydroxyleurosidine 14:814,815 acetyl derivative of 14:814,815 20'-deoxyleurosidine from 14:814,815 20'-deoxy- 15'-oxoleurosidine from 14:814,815 from anhydrovinblastine 14:814,815 Moffat oxidation of 14:814,815 thioxobenzoate derivative of 14:814,815 (15R')-20'-Deoxy- 15'-hydroxyleurosidine 14:814,815 acetylderivative of 14:814,815 from 20'-deoxy- 15'oxoleurosidine 14:814,815 20'-Deoxy- 15'-oxoleurosidine 14:814, 815 (15'R)-20'-deoxy- 15'-hydroxyleurosidine from 14:814,815 20'-deoxy- 15'-oxovinblastine from 14:814,815 from (15'S)-20'-deoxy- 15'hydroxy leurosidine 14:814,815 20'-Deoxy- 15'-oxovinblastine 14:814, 815
from 20'-deoxy- 15'oxoleurosidine 14:814,815 ( 15'R)- 15'-hydroxy-20'deoxyvinblastine from 14:814,815 12-Deoxy- 16-epi-acetoxyscalarafuran 6:122,123 synthesis of 6:122,123 2-Deoxy- 1-hydroxysugars 11:141 3-Deoxy- 1a-25-dihydroxyvitamin D3 10:70 synthesis of 10:70 Deoxy-24-epibrassinolide 18:50722-Deoxy-2-desmethlene bicyclomycin 12:87 synthesis of 12:87 2-Deoxy-2-fluoro-~-D-glucopyranoside 7:64 as [3-glucosidase inhibitor 7:64 2-deoxy-2-fluoroglucosyl fluorides 7:64 3-Deoxy-2-keto acids 30:423 formation of 30:423 3-Deoxy-2-oxa-25-hydroxy-vitamin D3 9:515,516 2-Deoxy-2-phosphinyl-D-tetritol 6:357 3-Deoxy-2-ulosonic acid 30:419,420, 434,460 stereoselective synthesis of 30:434 3-Deoxy-2-ulosonic acid 30:419,420, 434,460 family of 30:419 from carbohydrate precursors 30:460 structure of 30:420 1-Deoxy-2~3,3[3-epoxy nagilactone A 28:480 anti-feedant activity of 28:480 Deoxy-3- C-hydroxymethyl-13-Dglucopyranosyl 9-3-adenine 4:255 3-Deoxy-3-fluoro-D-myo-inositol 18:439 3-Deoxy-3-fluoro-sucrose 7:69 11-Deoxy-4-demethoxydaunomycinone 1:501 3-Deo xy-4- metho xy-D-manno-D-gluc ooctulosonic acids 30:450
234 4-Deoxy-4-phosphinyl-D-ribofuranoses 6:363-365 5-Deoxy-5-(alkylphosphinyl)-Dxylopyranoses 6:368 3-[ 5-Deoxy- 5(dimethylar sinoyl)-fl-Dribofuranosyloxy]-2-hydroxypropene-l-sulfonic acid 25:867 5-Deoxy-5-(ethylphosphinyl)-Lidopyranoses 6:373 5-Deoxy-5-(hydroxyphosphinyl)-Dglucopyranoses 6:370,371 5-Deoxy-5-(hydroxyphosphinyl)-Dmannopyranoses 6:374 5-Deoxy-5-(phenylphosphinyl))-Dxylopyranoses 6:368 5-Deoxy-5-(phenylphosphinyl)-Lfucosamine 6:369 from 2-azido-D-arabinohexofuranose 6:369 6-Deoxy-5-enohexopyranoside 10:510 Ferrier reaction of 10:510 5-Deoxy-5-phosphinothioyl-Dxylopyranoes 6:374,375 5-Deoxy-5-phosphinyl-Dglucopyranoses 6:369-372 5-Deoxy-5-phosphinyl-Dmannopyranoses 6:373,374 5-Deoxy-5-phosphinyl-D-ribopyranoses 6:368 5-Deoxy-5-phosphinyl-D-xylopyranoses 6:374,375 5-Deoxy-5-phosphinyl-L-idopyranoses 6:373 6-Deoxy-6-[(ethoxy) alkyl phosphinyl]D-glucopy-ranose 6:377
(+)- l-Deoxy-6-8-Di-epi-
castanospermine 12:350
(+)- 1-Deoxy-6-8a-Di-epi-
castanospermine 12:350 6-Deoxy-6-cobalt(III)-dimethylglyoximatopyridine 30:449 photolysis of 30:449 (+)-7- Deoxy-6-epi-castanospermJne 12:276
(-)- 1-Deoxy-6-epi-castanospermJne 12:350
7-Deoxy-6-epi-castanospermine 27:517 (-)-6-Deoxy-6-fluorocastonospermine 1-Deoxynojirimycin 12:332
6-Deoxy-6-fluoro-sucrose 7:69 as competitive inhibitors 7:69 3-Deoxy-7-phospho-D-arabinoheptulosonic acid 25:928 1-Deoxy-8-epi-ivangustin 7:214 from Artemisia pectinata 7:214 l'-Deoxy-abscisic acid 27:334 2'-Deoxyadenosine 10:592,593 3'-Deoxyadenosine (cordycepin) 10:592,593 11-Deoxyadriamycin 1:498 3'-Deoxy-aminoglycoside antibiotic 14:144-147 6-Deoxyandalusol 25:250 1-Deoxyanthracycline 14:481 Deoxyartemisinin 22:154 10-Deoxyaucubin 7:481 Deoxybouvardin 10:640-642;24:306 synthesis of 10:640-642 Deoxybouvardin methyl ether 10:640642 synthesis of 10:640-642 15-Deoxybruceolide 11:79,80,85,86 bmceantin from 11:79,80,85,86 1-Deoxy-castanosperine 12:347 (+)-6-Deoxycastanospermine 12:337, 338 synthesis of 12:337,338 (-)-6-Deoxy-castanospermine 12:346 2-Deoxychamaedroxide 23:609,610 3C-NMR data of 23: 610 ~H-NMR data of 23:610 Deoxycholate 9:565 2-Deoxycrustecdysone 19:466 8-Deoxycumambrin B 27:577 4-Deoxy-D,L-xylo-hexopyranose 14:178 synthesis of 14:178
6-Deoxy-D-altro-heptop yranoses
11:429 6-Deoxy-D-altroheptose 4:195 synthesis of 4:195 11-Deoxydanucomycinone 3:448,449 synthesis of 3:448,449 10-Deoxydaphylloside 7:470,471 3-Deoxy-D-arabino-2-heptulosonic acid 7-phosphate (DAHP) synthetase 30:424 structure of 30:424
235 3-Deoxy-D-arabino-2-heptulosonic acid methyl ester 30:434 3-Deo x y-D-arab ino-2-heptulosoni c acid-7-phosphate 30:431 from phosphoenolpyruvate and D-erythrose 4-phosphate 30:431 5-Deoxy-D-arabino-heptulosonate-7phosphate (DAHP) synthase 11:183,184 3-Deoxy-D-arabino-heptulosonic acid 7-phosphate 30:472 synthesis of 30:472 3-Deoxy-D-arabino-heptulosunate 7phosphate (DAHP) 740 3-Deo x y-D-arab ino-hexop yranose 14:148 3-Deoxy-D-arabino-hexose 14:143 2-Deoxy-D-arabino-hexose 14:176,177 asymmetric synthesis of 14:176,177 4-Deoxy-D-arabiono-hexose 14:143 11-Deoxydaunomycin 1:498 11-Deoxydaunomycinone 1:500,501 chiral synthesis 4:329,330 enantioselective synthesis of 1:596 synthesis of 1:500,501;4:327 7-Deoxydaunomycinone 3:449,450 synthesis of 3:449,450 3-Deoxydebromoaplysiatoxin 18:295 Deoxydehydropodophyllotoxin 26:213 cytotoxicity of 26:213 3-Deoxy-D-erythro-hexulosonic acid 30:437 by non-chelate-controlled process 30:437 3-Deoxy-D-e~ythro-hexulosonic acid 30:437 by non chelate-controlled process 30:437 1-Deoxy-D-galacto-heptulose 7:60 2-Deoxy-D-glucose 15:435 3-Deoxy-D-glycero -D-galacto-2nonulosonic acid 11:429,467 3-Deo x y-D-glyc ero-D-galacto-2nonulosonic acid (KDN) 30:420 3-Deoxy-D-glycero-D-galactononulosonic acid 30:427
preparation of 30:427 3-Deo x y-D-glyc ero-D-ga la c tononulosonic acid 30:427 preparation of 30:427 7-Deoxy-D-glycero-D-glucoheptose 26:373 4-Deoxy-D-lyxo-hexopyranose 14:176 asymmetric synthesis of 14:176 3-Deoxy-D-lyxo-hexose 14:143 4-Deoxy-D-lyxo-hexose 14:158 synthesis of 14:158 3-Deoxy-D-manno-2-octulosonic acid
11:429,440,441,464
3-Deoxy-D-manno-2-octulosonic acid 20:857 6-Deox y-D-manno-heptop yrano ses 11:429 6-Deoxy-D-mannoheptose 4:195 3-Deoxy-D-manno-octulosonate (KDO) aldolase 30:424 structure of 30:424 3-Deoxy-D-manno-octulosonate 8phosphate (KDO 8-P) synthetase 30:424 structure of 30:424 3-Deoxy-D-manno-octulosonic acid 30:419 2-Deoxy-D-ribofuranose 6:361 3-Deoxy-D-ribo-heptulosonic acid 30:437 3-Deoxy-D-ribo-hexofuranose 14:159 3-Deoxy-D-ribo-hexofuranoside 14:164 synthesis of 14:164 3-Deoxy-D-ribo-hexopyranose 14:148 4-Deo x y- D-ribo-he x op yranos ide 14:164 synthesis of 14:164 4-Deoxy-D-ribo-hexose 14:143,174 3-Deoxy-D-ribo-hexose 14:176,177 asymmetric synthesis of 14:176,177 3-Deoxy-D-ribo-hexose derivative 14:163 synthesis of 14:163 3-Deoxy-D-xylo-hexop yranose derivative 14:164,165 from methyl 13-D-galactopyranoside 14:164,165 4-Deoxy-D-xylo-hexose 14:143,147
236 3-Deoxy-D-xylo-hexose 14:143 9-Deoxyerythromycin A 13:175,176 6-Deoxyerythronolide B synthase 22:265 2-Deoxy-galactose 7:59 1-Deoxy-galactostatin 10:543 Deoxygalactostatin 7:41 Deoxygenation 1:391,392 with AIBN 19:516 with PBr3 1:391,392 of D-glucose 11:219 by zinc-copper couple 4:424 by zinc-dust 4:424 in steroid moiety synthesis 30:486 of ascorbic acid 4:420-423 of tert-alcohol 19:516 with Bu3SnH 19:516 with PBr3 1:391,392 12,13-Deoxygenation 6:234 of verrucarol 6:234 Deoxygeniposide 7:470 Deoxyglycyrrhetol 25:58 Deoxygomisin A 26:197,256 9-Deoxygoniopypyrone 19:463,19:497 5-Deoxygoniopypyrone 9:394 2'-Deoxyguanosine 8:377,378 Deoxyguanosine 8:388-392 Deoxyhemoglobin 26:986 3-Deoxy-hexoaldoses 14:144 4-Deoxy-hexoaldoses 14:144 2-Deoxyhexopyranosyl purimidines 4:229-232 2-Deoxyhexopyranosyl purines 4:229232 (6-Deoxyhexopyranosyl) adenines 4:232,233 3-Deoxy-hexoses 14:143-200 synthesis of 14:143-200 4-Deoxy-hexoses 14:143-200 synthesis of 14:143-200 Deoxyiodo-nucleosides 4:225 14-Deoxyisoamijiol 10:182 3'-Deoxykanamycin A 14:144,145 synthesis of 14:144,145 3'-Deoxykanamycin C 14:186 2-Deoxy-KDO 30:456 hydrogenation in 30:456 transformation of 30:456
2-Deoxy-KDO synthesis 30:470 concept of 30:470 (+)-5-Deoxykievitone 4:378,379 14-Deoxylactucin 29:89 activity in CRO assay system 29:89 Deoxylapachol 29:736 biosynthesis of 29:736 20'-Deoxyleurosidine 14:812 catharinine from 14:812 from anhydrovinblastine 14:871 oxidation of 14:812 3'-oxo-20'-deoxyleurosidine from 14:812 vincristine derivative from 14:818,819 20'-Deoxyleurosidine-N-oxide 14:872,873 5',6'-seco derivatives of 14:872,873 6-epi-7-Deoxylincosamine 11:446 4-Deoxy-lyxo-hexose 14:175 3-Deoxy-magellanol 18:745 4-Deoxy-magellanol 18:745 6-Deoxy-magellanol 18:745 5-epi-2-Deoxymakisterone A 19:468 3-Deoxymaltose derivative 14:163 from 3-chloro-3-deoxy-allo derivative 14:163 Deoxymannojirimycin 7:15,41,42; 10:528-538,540-542 chemico-enzymatic synthesis of 10:541 from Lonchocarpus costaricensis 10:538 from Lonchocarpus sericeus 10:538 from Omphalea dianadra L 10:539 from Streptomyces lavendulae 10:539 golgi c~-mannodiase I,II inhibitor of 10:539 golgi ~-mannosidase I inhibitor of 10:539 intramolecular aminomercuration of 10:540 synthesis of 10:528-538,540-542
237 ~-mannosidase inhibition by 7:15,41,42;10:539 [3-mannosidase inhibitor of 10:539 (+)-Deoxymannoj irimycin 18:347 3-Deoxy-maytol 18:745 5-Deoxymyricanon 17:371 18-Deoxynargenicin 17:298,301 synthesis of 17:298,301 Deoxynivalenol 13:519,538 4-Deoxynivalenol 6:221,224,225,243 Deoxynivalenol (vomitoxin) 6:230,231, 237,240-242;9:204-207,215,216 7-Deoxynogarol 14:47,78,79 (+)-7-Deoxynogarol 14:68-72 9-epi-7-Deoxynogarol 14:78 Deoxynojirimycin 7:14,15,41,42 1-Deoxynoj irimycin (1,5-dideoxy- 1,5imino-D-glucitol) 11:267;12:332 Deoxynucleoside-3-phosphorothioamidates 13:271 3-Deoxynucleosides 4:232 synthesis of 4:232 6-Deoxynucleosides 4:232 synthesis of 4:232 Deoxynucleosides 8:373 Deoxyparguerol acetate 25:788 12-Deoxyphorbol- 13-O-phenylacetate20-acetate 27:830 2-Deoxyphysalolactone 20:223 Deoxypicropodophyllin 26:213 cytotoxicity of 26:213 Deoxypodophyllin 26:193 (-)-Deoxypodophyllotoxin 24:767 synthesis of 24:767 Deoxypodophyllotoxin 26:167,214,215, 216 (-)-Deoxypodophyllotoxin 26:218; 30:568,588,589,595 Deoxypodophyllotoxin (anthricin) 26:193 (-)-Deoxypodorhizone 26:192,215,216 11-Deoxyprostanoids 1:639,640 2-Deoxyribose 6:337 8-Deoxyrifamycin W 23:62 3-Deoxyrosaranolide 11:164 synthesis of 11:164
(+)- 12-Deoxy-scalaradial 6:58,125-129 by Diels-Alder reaction 6:58 synthesis of 6:58,125-129 2-Deoxy-scyllo-inosose 11:217-219 2-deoxystreptamine from 11:217-219 4-Deoxysiastatin B 16:98 Deoxysikkimotoxin 24:767 asymmetric synthesis of 24:768 synthesis of 24:767 3-Deoxysilychristin 26:255 5-Deoxystansioside 7:462,463 2-Deoxystreptamine 11:217,218 from 2-deoxy-scyllo-inosose 11:217,218 14-Deoxystypodiol 6:55 from stypodiolmethyl ether 6:55 synthesis of 6:55 (-)-8-Deoxyswainsonine 12:304,332 14-Deoxy-taondiol methyl ether 6:55 from (+)-manool 6:55 synthesis of 6:55 Deoxytedanolide 19:558 antitumor activity of 19:558 3-Deoxytetrangulol 11:135 Deoxythymidine kinase 30:395 Deoxytrimethylbrazilone (B) 20:777 4-Deoxytromidioside 7:302 2-Deoxy-ulosonic acid analogues 30:467 for synthesis 30:467 3-Deoxy-ulosonic acids 30:435,451 construction of 30:451 synthesis of 30:435 20'-Deoxyvinblastine 14:863,864,871 16'-epi-Deoxyvinblastine 14:870,871
16'-epi-20'-epi-Deoxyvinblastine
14:870,871 from 15,20S-dihydrocatharanthine N-oxide 14:870,871 Deoxyxylulose 25:130
3-Deoxy-c~-D-arabino-2-heptulosonic acid (DHA) 30:420,439 from 1,4-cyclic sulfate and Darabinose 30:439 preparation of 30:439
3-Deoxy-ot-D-arabino-2-heptulosonic
acid-7-phosphate (DAHP) 30:420
238 3 -Deo x y-o~-D-a ra b ino-he x op yranos i de
derivative 14:156 3-Deo x y-(x-D-arab ino-he x op yranos yl-3deoxy-et-D-arabino- hexopyranoside
14:148
3 -Deo x y-et-D-a ra b ino-he x op yranos yl-
(x-D-glucopyranoside 14:148 6-Deoxy-c~-D-galactohexopyranosyl bromide 14:151 [2-Deoxy-(z-D-glyc-2-enopyranosyl] arenes 10:352,353 1-(2-D e oxy- c~-D-rib o-he xopyrano syl) cytosine cis-principle 4:586,587 endo-rule 4:587 in biogenesis 4:615-617 intermolecular 4:587-595 intramolecular 4:595-603 inverse electron demand 4:579, 580,604,605 lysergic acid by 4:504,605 manaomycin A by 4:591-593, 609 mechanism of 4:579,580 monomorine I by 4:606 nanaomycin d by 4:591-593 nepetalactone by 4:604,605 of acylnitroso 4:606 oxazoles in 4:604 palitantin by 4:588-590 prostaglandin by 4:607 pumiliotoxin by 4:584,585 regiochemistry of 4:584-586 retro 4:609-615 solanapyrone 4:598,599 stereochemistry of 4:586,587 stereochemistry of cycloaddition 4:122,123 terramycin 4:609 tetrazines in 4:604 triazines in 4:604 triquinanes by 4:588 vemolepin by 4:584,585 volume of activation 4:112 with heterodiene systems 4:583 with ketenacetals 4:357 with modified cyclohexadienes 4:583 with N-sulfinyl dienophile 4:356
with o-quinodemethone 4:583, 584 with a-amino aldehydes 4:120 [3-santalene by 4:607,608 2-Deoxy-o~-D-ribo-hexopyranosyl-2deoxy-ot-D-ribo-hexop yranoside
14:148 2-Deo x y-cx-D-ribo-he x op yranos yl-o~-D-
glucopyranoside 14:148 3-Deo x y-ot-D-xylo-he xop yranos i de
14:169 2-Deoxy-c~-glucose 7:59,60 2-Deoxy-c~-KDO 30:467 9-(6-Deoxy-ct-L-idopyranosyl) adenine 4:233 synthesis of 4:233 3-Deoxy-ot-L-xylo-hexopyranoside 14:182 1-(2-Deoxy-[3-arabino-hexopyranosyl) thymine 4:230 synthesis of 4:230 9-(6-Deoxy- [3-D-allopyranosyl) adenine 4:233 synthesis of 4:233 7-(2-Deoxy-13-D-arabino-hexopyranosyl) theophylline 4:233 synthesis of 4:230 3-Deoxy-p-D-furanurono-6,1-1actone 14:506 9-(6-Deoxy-[3-D-glucopyranosyl) adenine 4:233 synthesis of 4:233 2-Deoxy-[3-D-lyxo-hexopyranose 4:230 4-Deoxy-[3-D-xylo-hexop yranoside
derivative 14:164 7-( 3-Deoxy- [3-D-xylo-hexop yranos yl )theophylline 4:232 2-Deoxy-p-KDO 30:465 inhibitor of CMD-KDO synthetase 30:465 3-Deoxy-[3-L-hexofuranoside 14:182 2-Deoxy-p-Neu5Ac 30:468 approach to 30:468 4-epi-2-Deoxy-f3-Neu5Ac 30:468 approach to 30:468 6-Deoxy- p-ribohexopyranos-3-ulose 5:602
239
2-Deoxy-~3-ribo-hexopyranose 4:231 2-Deoxy-[3-ribo-pyranosyl cyanides 10:354 1-(3-Deoxy-[3-threo-pentofuranosyl) uracil 19:515 4-Deoxy-y-rhodomycinone 4:354 synthesis from mannose 4:354 synthesis of 4:352 Deoxy-~-santonin 7:212 Deposphoglycogenyl synthase 25:525 DEPC 4:92,93 cyclodimerization with 4:92,93 Dependent aldolases 30:423 synthesis of 30:423 Dephenyl thiolation 14:306 Dephosphorylation of retinoblastoma protein 25:270 Deplancheine 1:118 (+)Deplancheine 18:333Depolarisation 21:8,16,17,19,102 Depolymerisation 21:96 2-Deprenylrheediaxanthone B 30:620 from hypericum 30:620 Depressant activity 21:581 on central nervous system 21:581 Depression 30:368,627 role of hyperforin inhibitor 30:627 role of serotonin (5-HT) 30:368 Deprotection 4:282,283 of oligonucleotides 4:282,283 oftriethyl silyl group 4:533 with tetra-N-butylammonium fluoride 6:119-122 Deprotection alcohol 1:558 with TMSCIfNaI 1:558 Deprotonation 10:425 LDA-mediated 10:425 ofallylic ester 10:425 of 3-C-methyl-3-deoxy-2-ulose derivative 10:414,415 with N-lithio-2,2,6,6tetramethyl-piperidine 10:414, 415 asymmetric 11:241,242 azabicyclic ketone 11:241,242 Depsides 9:317,328
Depsipeptide antibiotics 21:408 Depsipeptides 9:213;10:250,251,256, 259,263,267,284,295-298;23:341 DER 30:800,814 antinociceptive effects of 30:800 resistance to enzymatic degradation 30:814 DER analogue 30:817 DER peptides 30:816 structural modifications of 30:816 Dercitamide 23:274;25:893,894 derivatives of 23:700 Dercitin sp. 25:893,894;28:686 antitumor activity of 28:686 antiviral activity of 28:686 immunomodulatory properties of 28:686 violet acridine alkaloid from 28:686 Dercitus 25:893 Derivatization 21:542 Dermaseptin I 23:341 Dermasterias imbricata 7:306;15:66; 25:824 2,4-di- O-methyl-[3-Dquinovopyranosyl-( 1>>2)-5O- sulphate-[3-D-fucofuranosyl from 15:66 imbricatine from 7:306 Dermatophagoides farinae 28:417
Dermatophagoides pteronyssinus 28:417-430
Dermatophilus congolensis 28:394 skin infection of cattle by 28:394 Dermatophytes 22:61 Dermocanarin I 20:277 Dermocibes sp. 22:556,579 Dermorphin 30:799,801,807,813,814 as 8 agonist 30:814 as ~t agonist 30:799 as ~t-selective agonist 30:807 inhibitory effects of 30:801 pharmacological activity of 30:813 Derris 26:487;27:844 Derris araripensis 7:177,193 Derris laxiflora 29:785
240 Derris Derris Derris Derris Derris Derris
nicou 7:177,193 scandens 27:844 sericea 7:177,193 trifoliata 7:176-178 ulignosa 7:181,182 urucu 7:177,193
Des-(25-28)-thymosin al 8:433,434 15-Desacaetylundulatone 26:816 (+)-Desacetoxymatricarin 14:357,358 Desacetoxymatricin 27:581 Na-Desacetyl- 17-O-acetyl- 18-hydroxyisoretuline 1:38,39 Na-Desacetyl- 18-hydroxyisoretuline 1:38,39 Desacetylakuammiline 5:126 N-Desacetyllappaconitine 25:528 Desacetyllaurenobiolide 27:564 N-Desacetylspermostrychine 26:1052, 1053 Desacetyltacraline 5:126 Desacetyltulipinolide- 1[3,10ot-epoxide 27:572 Desalanyl-N-acetylactinobolin 16:11 synthesis of 16:11 Desangelchrysamin 27:551 N-Desbutyl halofantrine 22:149 16R-Descarbomethoxytacamine 9:179,180 16S-Descarbomethoxytacamine 9:179,180 Descobalto-cobyrinic acid 9:598 15-Desenecioyl bruceoside-A 7:373 Desepo x y-4,5 -didehydro methylenomycin A 14:593 Desepoxymethyl enomycin A 14:602 Deserpidine 3:399,403,412-415;8:283; 9:171 ;13:631 ;19:748;21:84,488;25:8 from Rauwolfia serpentina 3:399,403,412-415 ;8:283; 9:171 ;13:631 ;19:748 synthesis of 3:412-415 Deserpindine (11-demethoxyreserpme) 25:8 Desethyleburnamonine enamine 14:729 17-oxy-20-desethyl-A2~ didehydroebur- namonine from 14:729 20'-Desethyl-20'-deoxyvinblastine 4:32;14:861
20'-Desethyl-20'-deoxyvincovaline 14:861 Desethylflavocarpine 1:137 synthesis of 1:137 Desethylibophyllidine 5:126 Desferrioxamine 22:328;26:992 Desformyl desoxypyoverdin D 9:550 Desformyl pyoverdin D 9:550 Desglucosylstevioside 15:18 from Rubus suavissimus 15:18 Desilylation 8:263 with HF-pyridine 8:263 of N-(trimethylsilyl) methyl iminium ions 1:325,328 with cesium fluoride 1:249 Desipramine 26:1063 D6sir6 and Prandi 29:455 carbafuranose synthesis by 29:455 Deslanoside 15:361,362 Desmal 25:546 Desmarestia menziesii 26:471 Desmethoxy streptonigrin 24:454 FPTase inhibition by 24:454 Desmethoxycuanzine 8:284-292 from 2-acetylbutyrolactone 8:284,285 synthesis from 8:284-292 Desmethoxytullidinol 22:574 Desmethyl quaternine 9:185,186 4-Desmethyl sterols 25:56,57 N-Desmethylacronycine 20:793 C18-Desmethylcytochalasin D 8:212217 synthesis of 8:212-217 5-Desmethylnobiletin 5:654 Desmethylvaracin 23:236 3,4-Desmethylvaracin 25:834 Desmia sp. (red alga) 5:343 Desmodium 21:525 Desmodium adscendence 21:659; 22:519 Desmodium polycarpum DC. 22:519 for convulsions 22:519 Desmodium pulchellum 22:519 for convulsions in infants 22:519 Desmodium styracifloium 25:93 Desmodium triflorum DC. 22:519 for convulsions 22:519
241 Desmopsamma anchorjkata 26:72 Desmotroposantonin 7:237 Desmutagenic activity 21:642 Des-N-methylnoracridones 13:352 Des-N-methylnoracronycine 13:370,371 synthesis of 13:370,371 Des- O-methyllasiodiplodin 9:288,289 Desorption techniques 13:652 Desosamine 5:615,616;13:155,156,159 ~-D-Desosaminyl methymycin 11:151 2-Desoxo- 15a-methyl- 14~-hydroxyMFA 28:347 discovery of 28:347 Desoxoalstonerine 13:402,403 Desoxodehydrolaserpitine 5:725,727 2-Desoxoparaherquamide A 28:331 nematocidal activity of 28:331 2-Desoxo-PHA 28:347 discovery of 28:347 Desoxy- 16-buxidienine 2:205 11-Desoxyanthracyclines 14:22 Desoxyasperdiol 10:29,30 by directed hydromagnesiation 10:29,30 synthesis of 10:29,30 Desoxybenzoin 4:382,384 robustic acid from 4:382,384 isorobustic acid from 4:382,384 11-Desoxydaunomycinone 14:23 asymmetric synthesis of 14:23 7-Desoxydaunomycinone 14:5,6 6-Desoxydaunomycinone 14:7 2-Desoxy-D-glucose 25:613 Desoxynivalenol (vomitoxin) 9:206, 207,217 218 13-Desoxyphomenone 6:552 from Hansfordia pulvinata 6:552 Desoxypicropodophyllin 18:552, 553,555,596 (+)-Desoxypodophyllotoxin 18:586, 588,59O Desoxypodophyllotoxin 5:480,481,483 Desoxyribonucleotides synthesis 26:924 18-Desoxy-Wieland-Gumlich aldehyde 1:36 Dess-Martin oxidation 19:370-371; 26:1244 Dess-Martin periodinane 19:357;23:190
Destomic acid 4:130 Destruxin-A4 chlorohydrin 25:800 Desulfonylation 19:77;11:349 Desulfurization 21:426 (+,-)-DET 6:263,269,271,278 Det2-cDNA 25:419 Detection 27:671 of sulfate groups 27:671 Dethioacetalization 12:348 Detox 28:543 for immunotherapy 28:543 Detoxification 21:4,108,161,165,177; 25:313,334,335,343 ;26:1012 of heme 25:334,335,343 of tomatine 25:313 of xenobiotics 26:1012 Detoxin 12:412 Detoxin B~ 12:412 Detoxin B3 12:412 Detraium microcarpum 21:611 Detritylation 4:276-279,282,284 Deuterated glycerol 11:422,423 asymmetric synthesis of 11:422,423 3-Deuterio-4-methylpyrocatechol 8:309 Deuteriosuccinic acid 8:72 27-Deuterocholesterol 5:774 3-Deuteroisoreserpine 25:8 Deuteromycotina 9:202 Deuteroporphyrin IX (DPIX) 25:355 Deutziol 9:455 Dexamethasone 5:713,714,602,605, 608;25:463,464 as down-regulator of TNF-a 25:465 as immunosuppressive drug 25:464 guggulsterones from 5:713,714, 602,605,608 3'-Dexoyadenosine 19:515 1-Dexoynojirimycin 10:543-546,549 antihyperglycemic activity of 10:526 antiviral activity of 10:529 by enzymatic aldol condensation 10:535,536 from Bacillus polymyxa 10:524 from Bacillus subtilis 10:524
242
from Bacillus amyloliquefaciens 10:524 from Bacillus 10:524 from Morus bombycis 10:524 from nojirimycin 10:524,525 from Omphalea diandra 10:524 from Streptomyces lavendulae 10:524 from Streptomyces lavendulae subsp, trehalostaticus 10:524 glycosidase inhibitors 10:525 intramolecular aminomercuration of 10:532 intramolecular reductive amination of 10:530 synthesis of 10:529-538 Dextran induced edema 25:46 Dextran sulphate 30:397,398 activity in quantitative syncytium formation assay 30:398 in HIV therapy 30:397 in vivo efficacy of 30:398 inhibitory effect of 30:398 on viral binding 30:398 endo-Dextranse 7:35,36 Dextransucrase 7:69 from Streptococcus sanguis 7:69 Dextrinase 10:504 Dextrins 10:463,464acatalytic hemihydrogenation 10:463 D-Glucono-nitriles 10:463,464 Nef reaction of 10:464 24-Dexyoxytrogenin 25:97 Dezoxiben 25:593 D-Gal N 25:466 hepatic intoxication with 25:466 D-Gal N/LPS 25:459-461 liver intoxication with 25:462 D-Gal N/LPS model 25:468 D-Gal N/LPS-induced liver injury 25:460,467,472-474 D-gal N/TNF-a 25:460,461 liver intoxication with 25:462 fl-l,6-D-galactopyranose 25:429 D-galactosamine (D-GaIN) 25:219,461, 463,465,468,471,473,477 ot-D-galactose 21:162,169
cx-D-galactosidase 21:160,161,168 D-GalN/LPS model 25:464 D-GalN/LPS-intoxication 25:468 D-GaiN-induced cytotoxicty 25:468 D-GaiN-induced liver injury 25:463, 469 [3-D-glucans 23:116 regular conformations of 23:116 D-Gluconolactone derivative 30:445 coupling of 30:445 [3-D-glucopyranosyl (1---~2)-[3-D-glucopyranosyl 21:732 D-Glucose 23:107 polymers of 107 D-Glucose aldehyde 30:443 role in aldol reaction 30:443 hydrogenation of 30:443 cyclization of 30:443 [3-1,2-D-glucosidase 25:306 [3-D-glucuronic acid 21:169 [3-D-glucuronidase 21:157,160,161,169 D-Glyceraldehyde derived allylic alcohols 10:436,437 Johnson-Claisen rearrangement of 10:436,437 D-glycero-D-allo/altro 30:442 diastereomeric mixture of 30:442
D-glycero-D-allo-2-nonulosonates 30:468
D-glycero-D-galacto/talo 30:442 diastereomeric mixture of 30:442 D-glycero-D-gluco/mann 30:442 diastereomeric mixture of 30:442
D-glycero-D-manno-2-nonulosonates 30:468
D-glycero-ot-D-talo-octulosonic acid 30:419 DHA 30:65,420 from carp oil 30:65 structure of 30:420 DHA-Chlorella 30:788,789,790 anti-hyperlipidemic effect of 30:788,790 DHEAsulfate (DHEAS) 24:351-398
243
Di(4,4'-hexyloxy-carbonylphenyl) ether 20:709 Diabrotica undecimpunctata 25:792 Diabrotica virgifera 26:867,868 Diacarms 25:688 2,4-Diacetamido-2,4,6-trideoxyhexopiranoses 30:434 condensation of 30:434 2,4-D iac etamido-2,4,6-trideo xyhexopiranoses 30:434 synthesis of 30:434 condensation of 30:434 Diacetone glucose 10:412 2,15-Diacetoxy- 13-hydroxy- 11 -epi APO 13:522 1(x,3[3-Diacetoxy-23,24-dinorchol-5-en22-ol 11:388-390 1c~,3~-Diacetoxy-23,24-dinorchola-5,7dien-22-al 11:398-402 synthesis of 11:398-402 3-( 2',3 '-Diacetoxy-2'-methyl-butyryl)cauhtemone 7:185 1,3-Diacetoxy-5-(2 '-acetoxy- 8 'oxotridecyl)benzene 30:132 structure of 30:132 1,3-Diacetoxy-5-pentadecylbenzene 30:128 structure of 30:128 2(x,7cx-Diacetoxy-6[3-isovaleroxylabda8,13-dien- 15-ol 17:27 1(x,2c~-Diacetoxy-6 p,9 p-difuroyloxy-4 phydroxydihydro- p-agarofuran 29:87 activity in EBV assay system 29:87 2,13-Diacetoxy-8-hydroxy- 11-epi APO 13:522 Diacetoxyavarol 15:300 1cx,3[3-Diacetoxychola-5,7-dien-24-al 11:398-402 synthesis of 11:398-402 1~x,3[3-Diacetoxychola-5,7-dien-24-ol 11:398-402 synthesis of 11:398-402 1c~,3~-Diacetoxychola-5-en-24-ol 11:388-390 5,8-Diacetoxynerolidol 27:587 Diacetoxyscirpenol 21:233
(-)- 15c~,16(x-Diacetoxyspongian 6:108, 109 Diacetyl dimethylbartogenate 7:132,133 3,13-Diacetyl GA3-7-aldehyde 8:128, 129 Diacetylajmaline 9:183,184 Diacetylenic allo-xanthin 6:150,153 C40-Diacetylenic carotenoids 6:149 3,13-Diacetyl-GA3 phenacyl ester 8:133,134 synthesis of 8:133,134 Diacetylirumamycin 5:599 ozonolysis of 5:599 N'~176 trimethylsilylethyl ester 21:394 2,4-Diacetylphloroglucinol 21:186 Diacetylsandwichine 9:183-185 Diacetylsarpagine 9:174 N,O-Diacetylsolasodine 20:490 Diacyglycerol (DAG) 25:271,483,487, 488,516,542 1,2,-Diacyl-3 a-D-glucuronospyranosylsn-glycerol taurieamide 25:873 Diacylglycerol 21:50 Diacylglycerol acyltransferase 25:797 Diacylglycerol- 1-oleolyl-2-acetyt-rac glycerol 25:488 1,3-Diacyloxypropanes 13:53,54 Diadematidae 7:283 Diadinoxanthin 23:178 Diadzein 22:458,460 Diagnostic criteria 30:372 for autistic disorder 30:372 Dialdehyde 8:18,19 18-epi-Dialdehydes 6:129 Dialkoxy anils 4:544 o~,f3-Dialkoxy ketone 11:235 2,6-Dialkoxy ketones 14:647 3,4-Dialkoxyfurans 12:19,20 Diels-Alder cycloaddition 12:19,20 with alkyl coumalates 12:19,20 Dialkyl azodicarboxylates [4+4] cycloaddition 12:424,425 to 3-[(1S)-2-exo-alkoxy- 1apocamphanecarbonyl]2-oxazolones 12:424,425 Dialkyl ethers 2:4
244
Dialkyl tartrates 14:489 2,6-Dialkyl-2-cyanopiperidines 6:431, 432 trans-2 ,5 -D ialkyl-3 ,4-de h ydrop yrro lines 6:441 synthesis of 6:441 trans-2,5-Dialkylated pyrrolidine 11:256,257 cis-c~,ot'-Dialkylated [3,[3'-heterosubstituted-oxocanes 10:214 Dialkylation 6:332,341 Dialkylboranes 9:366 cis-Dialkylpiperidine 19:34 2,6-Dialkylpiperidines 6:424-434 from 1-benzyl-2,6dicyanopiperidine 6:433 synthesis of 6:424-434 cis-2,6-Dialkylpiperidines 6:431,432 trans-2,6-Dialkylpiperidines 6:431,432 2,5-Dialkylpyrrolidine ant alkaloids 6:443 enantioselective synthesis of 6:443 2,5-Dialkylpyrrolidine s 6:437,438 by reductive amination 6:437,438 in Monomorium species 6:436 in thief ants 6:434 synthesis of 6:437,438 2,5-Dialkylresorcinol 9:322 Diallenic carotenoids 6:135,136 Diallyl cuprate 12:425,426 Diallyl disulfide (DADS) 459,469 Diallyl sulfide (DAS) 23:459,469 Diallyl thiosulfinate 23:457,459,467 Diallyl trisulfide (DATS) 341,459,469 3,5'-Diallyl-2'-hydroxy-4-methoxybiphenyl 24:861 anti-fungal activity of 24:861 (E,E)-Diallylic ether 8:196 synthesis of 8:196 Diamagnetic-y-gauche effect 9:119 5,7-Diamino-3,5,7,9-tetradeoxy-2nonulosonic acids 30:420 N-acyl and O-acetyl derivatives of 30:420 2,4-Diaminobutyric acid 9:547,548,553 2,3-Diaminoglucosyl analogs 6:406,407 meso-Diaminopimelic acid 6:404
Diaminopimelic acid-diaminopimelic acid (DAP-DAP) linkage 12:95 Diaminopimely-D-alanine 12:96 Dianchinenoside E 26:37 Dianchinenoside F 26:37 3,4:l',6'-Dianhydromaltose 10:511,512 from 2,3,2',3'-tetra- O-acetyl- 1', 6'anhydro-6-deoxy-4-O-p-tolylsulfonyl-[~-maltose 10:511 1,4:3,6-Dianhydromannitol D~-pbromobenzoate 2:164 1,6:3,4- D ianhydr o-13-D,L-allohexopyranose 14:184 Dianilinophosphoric chloride 18:397 Dianilinophosphoric esters 18:397 Dianilinophosphoryl chloride 14:286 Dianion 11:284,285 alkylation of 11:284,285 condensation of 12:9,10 from 4-[tert-butyldiphenylsilyl)oxy]-2-(tributyl-stannyl)(E)-2-buten- 1-ol 12:9,10 of FAMSO 6:323-325 stereoselective 11:284,285 with 1-TMS-2-pentyne 11:284, 285 with ot,13-epoxy cyclohexanone derivative 12:9,10 Dianion aldol condensation 12:69 Dianosides A-1 26:32 analgesic activity of 26:32 Dianthus barbatus 26:32,56 anti-inflammatory agent from 26:32 Dianthus caryophyllus 26:32,594; 29:593 Dianthus chinensis 26:3,32-34 Dianthus delloides 26:32 Dianthus sp. 5:659 acylated anthocyanins 5:659 malic acid in 5:659 Dianthus superbus var. longicalycinus 26.'56 anti-bleeding activity of 26:56 anti-tumor activity of 26:56 Diaperoecia californica 17:90,92 Diaphoretic agent 23:642 of Teucrium sp. 23:642
245 Diapo-carotenoids 7:317;20:602; 30:517,528 Diaporte helianthi 15:345 Diarrhetic shellfish poisoning (DSP) 28:653 yessotoxin in 28:653 Diarrhetic shellfish poisons 21:301 Diarrhoea 30:394,406,691 Celastrus gaumeri in treatment of 30:691 2,6-Diaryl-3,7-dioxa bicyclo [3.3.0.] octanes 24:740,755-762 Diarylalkanoids 27:852 Diarylbutanes 17:349 Diarylcyclobutanes 17:348 Diarylethanoid derivatives 30:222 moracins as 30:222 norlignans as 30:222 Diarylether 17:388 Diarylheptanoids 20:276;23:802,805; 25:543;27:852 activity of 17:375;27:852 1,7-Diarylheptanoids 26:881 Diarylpyrazoles 30:196,197,198 structure of 30:197 Dias synthesis 30:44-46 of (-)-pironetin 30:44-46 Diasesartemin 7:219 Diastereoconversion 12:479 Diastereodifferentiating isomerization 14:510 4-hydroxy-2-cyclopentenone acetal from 14:510 of meso-3,4-epoxycyclopentanone 14:510 Diastereofacial selection 13:62-70 Diastereofacial selectivity 4:172,173 of chiral epoxidizing agent 4:172,173 Diastereolselective alkylations 1:613-616 Diastereolselective cyclopropanations 1:629-632 of c~,[3-unsaturated acetals 1:629-632 Diastereomeric products 30:547 Diastereomeric resolution 1:585-588 Diastereomers 13:280-282;22:227, 231;27:363,364
Diastereoselection 10:215 1,2-Diastereoselection 4:443,448,451, 472,474 Diastereoselective 4:328,329;12:15,16 Diastereoselective addition 14:508,509 of chiral aryl Grignard reagents 14:508,509 to carbonyl compounds 14:508, 509 of Grignard reagents 1:621 to ketals 1:621 Dlastereoselective aldol reaction 30:431 ofpyruvate 30:431 Diastereoselective alkylation 17:324 Diastereoselective cyanation 14:473 Diastereoselective cyclizations 1:590,591 Diastereoselective cyclopropanation 6:544,545 Diastereoselective eliminative cleavages 1:618,619 Diastereoselective halolactonization 1:620,627-629 Diastereoselective Michael addition 6:86,87,286 Diastereoselective reduction 1:595 Johnson-Yamamoto rationale 1:595 ofcarbonyls 1:622 Diastereoselective routes 29:471 to carbaaldopyranoses synthesis 29:471 Diastereoselective synthesis 12:479-481; 27:208 of(3R,4R)-staine 12:479-481 of 2(c~-hydroxyalkyl) piperidines 12:453 of 4c~-aryldecahydroisoquinolines 12:456-463 of 6-hydroxy-4ct-phenyldecahydro 12:457 of B/C-trans-morphinan 12:464-471 of Blepharin 27:188,208,209 of octahydroisoquinolines 12:457 ofpiperidine derivatives 12:471 ofpyrrolidine derivatives 12:471
246
of methylphosphonate 13:276-278 of phosphorothioate 13:276 Diastereoselectivity 11:359;16:372 Diastereotopic groups 17:481 Diastrovaricin 23:54 Diastrovaricins I 23:67 Diastrovaricins II 23:67 Diatoms 21:300,302 Diatoxanthin 20:579,580;23:179 Diatretyne nitrile 21:190 Diatriba 25:186 1,4-Diazabicyclo [2,2,2]-octane 27:850 1,5-Diazabicyclo [4.3.0] non-5-ene 11:353 Diazabicyclo [5,4.0] undecene 12:466 1,8-Diazabicyclo [5.3.0] undec-7-ene 11:341,342 3,8-Diazabicyclo[3,2,1] octane 10:135137 synthesis of 10:135-137 Diazabicyclo[5.4.0]undec-7-ene (DBU) 424,425 Diazene 3:20;22:196,197,200,204, 213,214,219,220,233 Diazepam binding inhibitor 27:803 Diazidation 10:465 ~x-Diazo [3-keto ester acetal 14:509 2-Diazo-3-oxopentanoic acid derivatives 12:172 with 4-acetoxy [3-1actam 12:172 3,8-Diazobicyclo [3,2,1] octane 10:107,117 Diazoketone 1:492 cyclization of 1:492 from adenosine 10:593-595 preparation of 10:593-595 Wolff rearrangement of 10:593-595 a-Diazoketone 19:18 Diazoketone insertion 1:555,556,564 copper mediated 1:555,556,564 cyclization 1:492 Diazomethane 1:404,405,439 esterification of 1:404,405 methylation with 1:435 ring expansion with 3:12
sugar aglycone linkage cleavage by 7:155,156 Diazosulfone 22:331 Diazotization 3:325,226 Diazotized aniline 19:89 DIBAH reduction 6:428;14:634;19:172 DIBAL 1:177;14:529,530;19:318 reduction with 6:285,286,288, 293,294,299,549,550;11:432, 457;13:456,464,465;20:67 DIBAL reduction 21:391 Dibalanocarpol 23:533;26:556,562 (DIBAL-H) reduction 10:428,429 of ot,[3-unsaturated ester 10:428,429 Dibenz [b,d] oxocin derivative 15:34,35 Dibenz [b,g] azecine derivative 6:492, 493 Dibenz [c,g] azacycloundecine 6:496 Dibenz [c,g] azonine derivartive 6:474, 475 Dibenz [d,f] azonine derivatives 6:477, 478,480 from benzylisoquinoline derivatives 6:477,478,480 from 1-halogenobenzylisoquinoline 6:482 from neoproaporphine intermediates 6:480 from neospirene intermediates 6:480 synthesis of 6:477,478,480,482 Dibenz[b,f] azecine derivative 6:492,493 Dibenzazecine 6:487-493 Dibenzindolizidine 3:425 Dibenzlbutyrolactone enerolactone 26:186 Dibenzo [d,f] azonines 3:468,469 Dibenzo oxazacycloundecine derivatives 6:494 Dibenzoate 10:597 from cis-2-buten-l,4-diol 10:597 from D-glucose 10:597 Dibenzocyclooctadiene 24:775-781 derivatives of 24:775-781 synthesis of 24:775-781 Dibenzocyclooctadiene lactone lignans 29:360
247 araliangin as 29:360 10-demethoxystegane as 29:360 episteganangin as 29:360 (-)-9-episteganol as 29:361 neoisostegane as 29:360 steganolides as 29:360 X-ray structure of 29:361 Dibenzocyclooctadiene lignans 26:196, 197 Dibenzocyclooctadienes 17:346 Dibenzocyclooctanes 20:276 Dibenzopyrrocoline alkaloids 6:482 Dibenzoquinolizine 6:492,493 hexahydrodibenz [d,g] azecines from 6:492,493 Dibenzoyl-p-D-ribopyranose 10:589,590 condensation of 10:589,590 N, N-Dibenzyl benzoyl acetamides 14:650,651 photolysis of 14:650,651 (4S,5R)-3,5-Dibenzyl-4-isobutenyloxazolidin-2-one 12:480 Dibenzylazodicarboxylate (DBAD) 12:157 Dibenzylbutane enterodiol 26:186 Dibenzylbutane lignans 26:191 Dibenzylbutane nordihydroguairetic acid 26:187 2,3-Dibenzylbutane- 1,4-diol 26:191, 234,249,250 inhibition of Ca2+ influx 26:234 Dibenzylbutanes 17:315 Dibenzylbutyrolactone 30:570 Dibenzylbutyrolactone yatein 29:369, 371,380 steganes synthesis from 29:369, 371,380 Dibenzylbutyrolactones 5:485-490,320; 30:587 Dibenzylbutyrolactone-type lignan 30:587 tris-Dibenzylideneacetone dipalladium 8:277,278 (-)-(2S,3S)- 1,4-Dibenzyloxy-2,3butanediol 14:490 unsaturated acetal from 14:490 Dibenzyltrisulfide 28:403 as oviposition inhibitor 28:403
(2S,6R,8R,9R) 2,8-Diboromo-[3chamigrene 6:62,63 from (8R,9R)-8-bromo-9hydroxcy-(E)-y-bisabolene 6:62,63 synthesis of 6:62,63 Dibroinoageliferin 25:779,780 Dibromide synthesis 29:482,483 as fucosidase inhibitors 29:482 by Rassu 29:482,483 2,6-Dibromo-3-methylbenzoquinone 21:434 endo-3 ,9-Dibromo-4-bromomethyl camphor 4:629 reactivity towards bromination 4:629 7-syn-9-Dibromo-6-endomethylisofenchone synthesis 4:629 (-)-(2R, 6S, 8S,9S)-2,8-D ibromo-9hydroxy-c~-chamigrene 6:62,63 by asymmetric carbocyclization 6:62,63 from (E)-~-bisabolene-8(R),9(S) epoxide 6:62,63 from Laurencia nipponica 6:63 synthesis of 6:62,63 (+)-3,9-Dibromocamphor 16:138 (+)-9,10-Dibromocamphor 16:138 (+)-3,3-Dibromocamphor 4:628,629, 638,639;16:144 (+)- 10-bromocamphor from 4:638,639 (+)-endo-3 ,9-Dibromocamphor 4:634,635,643 acid catalysed rearrangement 4:635,643 reactivity towards bromination 4:629,630 (+)-9,10-Dibromocamphor 4:657,658 C(3)-methylation of 4:657,658 Dibromophakellstatin 25:770 2,6-Dibromophenol 17:81 2',4'-Dibromophenoxy ether 21:284 4,5-Dibromopyrole-2-carboxylic acid 26:819 methyl-ester of 26:819 Dibromosceptrin 21:73;25:779 3,5-Dibromotyrosine 21:307
248
Dibromo-tyrosine derivatives 25:719 Dibromotyrosine-derived metabolites 25:719 Dibromoverongiaquinol 21:307 4,5-Dibrompyrrole-2-carbamide 25:784 Dibutyl cAMP 25:271,488,509 Dibutyltin oxide 1:274 for stannoxane preparation 1:274 1,2-Dibutyroyl inositol 18:409 4,5-Dicaffeoyl quinic acid 23:764 Dicaffeoyl tartaric acid 25:663,667,932 Di-caffeoylquinic acid 23:753 1,5-Di-caffeoylquinic acid 23:753 1,4-Di-caffeoylquinic acid 23:753 3,4-Di-caffeoylquinic acid 23:753 3,5-Di-caffeoylquinic acid 23:753 Dicaffeoylquinic derivatives 23:745 Di-C-alkylation 10:413 of D-mannose derivative 10:413 5,7-Dicarbanion 21:746 [3-Dicarbonyl 10:343-348 Dicarbonyl coupling 3:99 by Mukaiyama procedure 3:99 intramolecular 11:345,364-467 with TiC13/LAH 3:80,81 with TiCI3/Zn-Cu 3:80,81 ot-Dicarbonyls 8:262 synthesis of 8:262 Dicentra spectabilis 27:163 Dicentrine 21:73;22:20 Dicerocaryum zanguebricum 26:1158 6,8-Di-C-glucosyldiosmetin 23:747 Dichamanetin 9:399,400 1,3-Dichloro- 1,1,3,3-tetraisopropyldisiloxane 18:409 2,3-Dichloro-4,5-dicyanobenzoquinone (DDQ) 11:156,165 2,3-Dichloro-5,6-dicyano- 1,4-benzoquinone 21:735 Dichlorobis (acetonitrile) palladium (II) 21:381 Dichlorocarbene addition 10:413 Dichloroimine 21:346 2,6-Dichloroisonicotineic acid 26:946 Dichloroketene 13:6 [2+2]cycloaddition with 13:6 Dichlorolissoclimide 25:269,769 (Dichloromethyl) boronic ester 11:409, 410
synthesis of 11:409,410 (Dichloromethyl) lithium 11:410 Dichloromethylenation 3:223 Dichloromethylphosphine 13:276 9,10-Dichloro-N-methyldysideathiazole 25:890 2,6-Dichlorophenol 25:765 2,4-Dichlorophenol 25:767 2,4-Dichlorophenoxy acetic acid 7:90, 97,111;26:306 Dichomine 5:126,183 Dichomine-type alkaloids 5:106 Dichroa febrifuga 20:522;22:146 Dichrostachys cinerea L. 22:519 for epilepsy 22:519 Diclofop 26:374 6,6-Di-C-methyl heptopyranose derivative 10:414 3,3-Di-C-methyl-2-ulose 10:415 2,2-Di-C-methyl-3-deoxy-4-ulose 10:414,415 2,2-Di-C-methyl-3-ulose 10:415 4,4-Di-C-methyl-4-deoxy-D-glycerohexo-pyranoside-2-ulose 10:414,415 Dicoumarol (coumarin) 27:847;29:584 effects as anticoagulant 29:584 Dicraeopetalum stipulare 27:271 Dicranostigma ' .'mchetianum 27:162 Dicranostigma tactucoides 27:155,162 Dicranostigma leptopodum 27:162 Dicrotalic acid 21:730,732;22:169 Dicrotaline 1:271 Dicrotonic acid 7:143,144 Dictamine 3:385,386 Dictamnus albus L. 22:519 for hysteria 22:519 Dictindiol 9:79,80,87 Dictinol 9:79,87 Dictintriol 9:79,80,87 Dictydiaethalium plumbeum 12:366,370 arcyriaflavin-D from 12:366,370 Dictyoceratida 6:107,111;19:568 Dictyoceratidaquinone 15:300 Dictyoceratin-A 5:432,433,292,293 Dictyochromenol 15:294 Dictyodendrilla cavernosa 18:718 Dictyodendrilla sp. 28:691 Dictyodial 5:370
249 (-)-Dictyolene 6:27 by Collins allylic oxidation 6:27 from Dictyota acutiloba 6:27 from 6-epi-c~-santonin 6:27 synthesis of 6:27 Dictyoloma incanescens 26:820 Dictyoloma peruviana 26:820 Dictyoloma vandellianum 26:820 Dictyolomide 26:821 Dictyols 17:97 Dictyoptera 22:371 Dictyopteria genus 25:841 Dictyopteris divaricata 6:16,18 dictyopterone from 6:16 [3-dictyopterol from 6:16,18 (-)-zonarene from 6:15 Dictyopteris undulata 6:17 isozonarol from 6:17 zonarol from 6:17 Dictyopteris zonaroides 6:15 (-)-zonarene from 6:15 13-Dictyopterol 6:18,19 by Peterson olefination 6:18,19 by van de Walle approach 6:16 from Dictyopteris divaricata 6:16,18 synthesis of 6:16,18,19 13-Dictyopterol precursor 6:16 from c~-phenylselenide 6:16 synthesis of 6:16 Dictyopterone 6:16 by van de Walle approach 6:16 from Dictyopteris divaricata 6:16 synthesis of 6:16 Dictyostatin 19:557 Dictyostelium 9:220 Dictyostelium discoideum 5:275,384; 25:523;26:80 Dictyosterol 30:505,507 13C NMR spectra of 30:505 IH NMR spectra of 30:505 synthesis of 30:507 Dictyota 9:78,79,86 Dictyota acutiloba 6:27 (-)-dictyolene from 6:27 Dictyota crenulata 5:370,70;6:70 Dictyota dichotoma 9:86,88
Dictyota divaricata 6:52 Dictyota indicia 9:78-81 Dictyota linearis 6:52 (+)-amijitienol from 6:52 dolasta- 1 (15)-7,9-trien- 14-ol from 6:52 isoamijiol from 6:53 Dictyota spinulosa 5:370 Dictyotaceae 6:52 dolastanes from 6:52 marine diterpenes from 6:52 Dictyotene 21:305 Dicyclic-O-glucoside 22:427 1,2-Dicyclohexyl-l,2-ethanediol 11:423 (S,S)- 1,2-Dicyclohexyl- 1,2-ethanediol dichloromethylboronate 11:423,424 from chiral 1,2-diphenyl ethanediol 11:423,424 (m-methyl crotyl) boronic ester from 11:423,424 Dicyclohexylborane 4:116,117 Dicyclohexylcarbodiimide 12:328 N,N-Di-cyclohexylcarbodiimide (DCC) 8:76 Dicyclohexylideethane 4:521 synthesis of 4:521 1,2:4,5-Dicyclohexylidene-myo-i nosito 1 18:401 Dicyclohexylidene-myo-inositol 18:403 Didanosine 24:474,486,488 as anti-viral agent 24:474,486, 488 Dideacetoxy argutin 9:66 7,8-Didehydro acetylenic analogue 30:521 E-2,3-Didehydroaspartic acid 15:347 1,2-Didehydroaspidospermidine 26:1050 E-2,3-Didehydroisoleucine 15:347 7,8-Didehydroisorenieratene 6:155,156 15,15-Didehydromimulaxanthin 20:580 3,4-Didehydroproline 15:347 3,4-Didehydrovaline 15:347 11,11 '-Didehydroxy-7,7-dihydroxytaxodione 20:680 from Salvia montbretii 20:680 Didemenin 13 21:252 Didemenins 21:321
250 Didemethoxycarbonyltetrahydrosecamine 5:141 Dideminine B 12:455 from Trididemnum species 12:455 Didemnakelal 25:874 Didemnenones A,B 10:244,245 Didemnid tunicate 23:234 Didenmidae 10:250 Didemnimide A 23:258 Didemnimides B 25:802 Didemnin 12:412;25:684,714 Didemnin X 10:250-257 Didemnin A 4:84,102-106,421, 422-258,262,263,266-272,276,277, 281,285,291 ;10:251-256,258-262, 265,266,268-272,275,276,281,285, 291 Didenmin B 5:421;25:713,757,816 antitumor activity of 5:421 antiviral activity of 5:421 immunosuppressive activity of 5:421 Didemnin C 4:103-106,276,281, 285,291 ;5:421 ;10:251,254,271, 272,281,285,291,292 Didemnin D 5:422 Didemnin E 5:422,250-257,299 Didemnin F 5:426-428 Didemnin G 5:427 Didemnin group 4:83 Didemnin Y 10:250-257 Didenmin-B (isodidemnin-I) 10:251-258,262,263,266272,276,277,281,285,291 Didemnins 5:421,254-257 antitumor activity of 5:421, 254-257 antiviral activity of 5:421,253, 254 biological properties of 10:241-302 cytotoxic activity of 5:421 immunosuppressive activity of 10:257,258 Didemnolin A 25:818 Didemnolin C 25:818,863 Didemnolin D 25:818,863 Didemnolines 25:757,816
Didemnum 25:878 Didemnum candidum 23:257,259 Didemnum chartaceum 23:248;28:631 lamellarin G 8-sulfate from 28:631 lamellarin sulfates from 28:631 lamellarin B from 28:631 lamellarin C from 28:631 lamellarin L. from 28:631 Didemnum chartcium 17:22 Didemnum conchylatum 23:258;25:802 Didemnum molle 25:883;28:630 comoramide A from 28:630 comoramide B from 28:630 cyclodidemnamide from 28:630 mayotamide A from 28:630 mayotamide B from 28:630 mollamide from 28:630 Didemnum rodriguesi 25:813, 897;28:632 caledonin from 28:632 Didemnum sp. 10:24;25:765,818,874; 28:631,634 anti-human immunodeficiency virus (anti-HIV) activity of 28:631 didemnaketal C from 28:631 didemnoline A from 28:634 didenmoline D from 28:634 polysaccharide from 28:631 Didemnum ternataum 23:234 Didemnum voeltzkowi 10:244;25:713 Dideoxy C-glycoside 10:389 2,3-Dideoxy ulosonic acids 30:465 as precursors 30:465 importance of 30:465 1,4-Dideoxy- 1,4-imino-L-allitol 7:41-43 N-benzylation of 7:41-43 N-methylation of 7:41-43 1,5-Dideoxy- 1,5-imino-D-glucitol 12:332 from D-glucose 12:332 synthesis of 12:332 1,5-Dideoxy- 1,5-imino-L- fuc itol 7:41,42 2,2-Dideoxy-2,3'-diphthalimido-13,[3trehalose 6:400
251 4,5-Dideoxy-4-phoshinyl-Llyxofuranoses 6:362,363 2,4-Dideoxy-4-phosphinyl-D-erythropento-furanoses 6:361,362 2,4-Dideoxy-4-phosphinyl-L-threopento-furanoses 6:361,362 4,5-Dideoxy-4-phosphinyul-Dribofuranoses 6:362,6:363 5,6-Dideoxy-5-(phenylphosphinyl)-Lidopyranoses 6:372 4,20-Dideoxy-5-hydroxyphorbol derivative 2:267 5,6-Dideoxy-5-phosphinyl-Didopyranoses 6:372 2,3-Dideoxyascorbic acid 4:715-718 7,11-Dideoxydaunomycinone 1:503,504 7,9-Dideoxydaunomycinone 1:505 9-(2,3 D ideo xy-D-erythrohexopyranosyl)-adenine 4:2355,6-Dideoxy-D-glucopyranoses 6:366,367 5,6-Dideoxy-D-idopyranoses 6:366,367 3,13-Dideoxy-evoninol 18:746 Dideoxyforskolin 25:269 1,2-Dideoxy-galactose 7:65 2,3-Dideoxy-hex-2-enopyranoside 10:418 (S,S)-3,4-Dideoxyhexitol 11:251-259 Dideoxyhexoses 11:214,215 by TDP glucose oxidoreductase 11:214,215 from glucose 11:214,215 in Streptomyces violaceoruber 11:214 7,9-3',4'-Dideoxykanamycin B 14:145 2,3-Dideoxy-maytol 18:745 3,4-Dideoxy-maytol 18:745 1,6-Dideoxynoj irimycin derivatives 7:42 Dideoxynucleosides 4:234 4,6-Dideoxynucleosides 4:234 2,3-Dideoxypyranosyl-purines 4:235 4,6-Dideoxy-sucrose 7:42 4,4'-Dideoxy-trehalose derivative 14:165 from 4,4'-diiodide 14:165 from trehalose 14:165
10-(2,6-Dideoxy-13-arabinohexopyranosyl) cytosine 4:234 (-)-(9R)-7,11-Didesoxy- 13deoxodaunomycinone 14:8 10,12-Dideuterated reserpine 25:10 Didicus flavus 23:165 Didrovaltrate 16:295 from Valeriana wallichii D.C. 16:295 synthesis of 16:296-297 Didymium bahiense var. bahiense 29:252 constituents of 29:252 fruit bodies of 29:252 Didymium iridis 29:248 Didymium minus 29:250 clerosterol from 29:251 clionasterol from 29:251 constituents of 29:250 22,23-dihydrobrassicasterol from 29:251 glycoside glucoclionasterol from 29:251 isofucosterol from 29:251 24-methylenecholesterol from 29:251 poliferasterol from 29:251 Didymium squamulosum 29:247 Dieckmann condensation 3:191,289, 338,339;8:192,284,293 of ethyl 2-[ 1-(2-ethoxycarbonylmethyl) piperidinyl]-proponoate 12:284 of ethyl 4-[ 1-(2-ethoxycarbonyl pyrrolidinyl)]butyrate 12:293 Dieckmann cyclization 1:183,340; 10:328,408,410,411;12:126,147, 279,308,445;13:25,26,117,131 - 133; 14:34,35 ;24:3,33-35,42,43 Diels-Alder dimerization 2:122,128 endo Diels-Alder adduct 6:33,34 in (+)-precapnelladiene synthesis 6:33,34 Diels-Alder adduct 4:388,389;6:84,85, 125,340,451 Diels-Alder chemistry 16:9 ofbicyclic intermediate 16:9 Diels-Alder cyclisation strategy 30:220 Diels-Alder equivalents 3:4
252 reaction 8:150; 26:111,138 Diels-Alder reactions 20:769,770; 21:211,434;24:8-10,27-31,195196,762,763,766,768;26:172;30:661 asymmetric 12:26,27;24:768 asymmetric intramolecular 14:502,503 atomic orbital coefficients in 4:585,586 betaenone B by 4:601,602 cadinane by 4:584,585 (+)-capnellene by 4:588 cholesterol by 4:587 (+)-coriolin by 4:588 coronafacic acid 4:590,591, 596,597 cycloaddition 16:7,219,245,422 diastereoelectivity of 4:441 dienes in 4:581-584 dienophiles in 4:584 diplodiatoxin by 4:500-602 effect of Lewis acids 4:586 Eu (fod)3-mediated 4:121,122, 143 exo versus endo transition state 1:373-374 facial selectivity in 10:351 for bicyclic compounds 8:410 frenolicin by 4:591,592,594,609 gephyrotoxin 223AB by 4:606 hetero 1:478 heterodienes in 4:583 heterodienophiles 4:112,583 high pressure 4:112,121,122 (+)-hirsutene by 4:588 imino 1:288,289;4:604,605 iminodienophile in 4:604,605 in (q-)-A 9(12) capnellene synthesis 6:46 in (+)-12-deoxy-scalaradial 6:58 in anthracyclinone synthesis 1:502,503 in synthesis of quinolines 3:387397 intermolecular 12:19,20,380; retro-Diels-Alder
10:409;12:19,20,380;16:4,24
456 intramolecular 1:71,347,478,
479;3:79,80;8:403-406;10:51, 52,155,156;11:11,92,93,99-108; 12:253;13:108,117-141,144, 149;14:735;19:11,464 intramolecular imino 1:385-382 intramolecular nitroso 1:379381,383 inverse electron demand 3:311; 16:433 Lewis-acid catalyzed 8:141; 12:26,27 non-catalyzed reaction 8:142 odd carbon equivalent 3:419 of 1,3-butadiene 19:68 of 3,4-dialkoxyfurans amides 12:19,20 of amine 16:474 of butadiene 11:340,341 of chiral 1;3-dieneacylnitroso 19:11 of chiral o-quinodimethanes 14:502,503 of daunosamine derivative 10:375 of dimethyl acetylenedicarboxylate 12:379,380 of enal 19:66 of enantiomeric tetraenic acid derivative 10:409 ofenedione 16:28,34 of furan 19:366 offuran dienes 12:253 of imines 3:55 of isoprene 19:226 of levoglucosenone 14:270,271 of methyl-(E)-3-acetoxyacrylate 11:306,307 of N-carbomethoxy pyrrole 19:77 of N-furfuryl-~-chloroacryl amides 12:19,20 of N-substituted pyrroles 19:77, 226 of optically active nitroolefin 19:144 of orthoquinodimethane 11:92, 93 of perezone 5:768 of pyranose diene 10:351
253
ofpyridyl dienophile 19:75 of styrene 16:555 precursor of 16:5,261 regioselectivity 12:16,17 retro-Diels-Alder reaction 14:821,822 stereoselectivity 12:16,17 stereospecific 19:6 transition state of 16:5 with (E)-crotonic acid 11:340, 341 with 2-azaallyl anions 1:347 with acetal 14:502,503 with bis (nitrophenyl) butadiene 12:379,380 with butadiene 11:356,357 with Danishefsky diene 16:10; 19:144, 208 with doubly activated butadienes 3:465 with isoprene 11:306,307 with ketoester 19:226 with methyl vinyl ketone 19:208 with nitroso compounds 1:359392;12:16,17,250,253,416 with ~-quinonediimide 3:322323 Diemenensin A 17:24 antibacterial activity of 17:24 Diemenensin B 17:24 (Z,E)-Dienamide 21:436 (2E,4E)-Dienamides 21:374 Dienamides 21:378 E-Diene 16:4 Diene chromophore 11:369 Diene dimerization 3:107 Ni(O)-catalysed 3:107 (Z,E)-Diene ester 12:46,47 Diene isomerization 1:447,448 7,9(11)-Diene seychellogenin 15:91 Diene synthesis 6:308 Diene-carbenoid addition 3:49 [3-Dienes 3:38,39 synthesis of 3:38,39 Dienes 4:525 formation by reductive elimination 4:525
1,3-Dienes 8:278,280 cyclization of 8:278,280 palladium catalyzed 8:280 ~-Dienes 3:38,39 cyclopenthesis from 3:38,39 Dienic acid 3:38,39,41 synthesis of 3:38,39,41 Dienic macrolides 8:240 Z,Z-1,4Dienol disilyl ethers 12:172 Lewis acid cataylzed 12:172 with 4-acetoxy-[3-1actam 12:172 Dienone-phenol rearrangement 2:253, 615,625,628;19:406 Dienophiles 12:17 from L-ascorbic acid derivatives 12:17 synthesis of 12:17 in Diels-Alder reactions 4:583 3-Dienoyl tetramic acid 14:109 Dienoylpyrrol-2(5H)-one 13:120-123 c~,[3~,,6-Dienoyltetramic acids 14:104 8,13-Di-epi-sclareol 25:252 Di-epi-7-con-O-methylnogarol 14:75, 76,78 3,8-Diepialexine 7:14 3,24-Diepibrassinolide 18:530 3,24- Diepibrassinolide- 3[3-laurate 18:533 3,24- Diepibrassinolide- 3 [3-myri state 18:533 3,24-Diepibrassinolide-3[3-palmitate 18:533 (+)- 1,8c~-Di-epi-castanospermine 12:335,336,345 synthesis of 12:335,336,345 (+)-6,7-Di-epi-castanospermine 12:337,338,345 synthesis of 12:337,338,345 (-)- 1,6-Di-epi-castanospermine 12:342344 synthesis of 12:342-344 1,6-Di-epicastanospermine 7:12 from L-gulonolactone 7:12 synthesis of 7:12 3,24-Diepicastasteron 18:496,530 2,3-Di-epi-mannostatin A 19:356 8,13-Di-epi-manoyl oxide 20:691
254 (-)-l-8a Di-epi-slaframine 12:312synthesis of 12:312 (-)-8,8a Di-epi-swainsonine 12:331,332 inhibitory activity of 12:331,332 (-)-1,8- Di-epi-swainsonine 12:325 from (S)-glutamic acid 12:325 from methyl 3-acetamido-2-Oac etyl-3- de oxy-4,6- di- O- me syl(x-D-glucopyranoside 12:326,327 (+)-2,8-Di-epi-swainsonine 12:325 (-)-2,8a-Di-epi-swainsonine 12:325,331 (-)-8,8a-Di-epi-swainsonine 12:331,332 divergent synthesis of 12:330 from 2,3-O-isopropylidene-Lerythrose 12:330,331 inhibitory activity of 12:331,332 synthesis of 12:329-332 Diepomuricanin A 18:212,219 (R,R)-Diepoxide building block 11:251,252 (S,S)-Diepoxide building block 11:251,252 7c~,8 c~,13[3,14[3-Diepoxyabietan- 18-oic acid 29:99 activity in EBV assay system 29:99 1613,23,16c~,24-Diepoxycycloartane compounds 27:472 2,3-Diepoxy-D-arabino-hept-2-enono1,4-1actone 11:457 trans-3,3-Diethofencarb 22:462 Diethoxy- 1,2-cyclobutane dicarboxylate 10:613,614 Diethoxyphosphono acetate 9:525 Diethyl (L)-tartarate 14:508 chiral ortho esters from 14:508 (+)-monomorine I from 6:44 Diethyl [2-2H2, 2-13C] succinate 11:196 Diethyl 2,2'-bi- 1-benzoate 11:125 Diethyl aluminum 2,2,6,6-tetramethyl piperidine 10:48 Diethyl amino (di-t-butoxy) phosphine 14:305 Diethyl phosphorocyanidate (DEPC) 4:83
Diethyl phthalate 11:124 9-oxo-3-fluorenelacetate from 11:124 (R,R)-Diethyl tartarate 11:346 Diethyl-3-oxo-glutarate 6:445 condensation of 6:445 with 4-aminooctanal diethyl acetal 6:45 wit ethanol 6:445 Diethylaluminum cyanide 3:213 Diethylamine 22:220 2'-Diethylamino rifamycin P 23:95 Diethyldithiocarbamate 26:1271 Diethylnitrosamine 12:399 Diethylstilbesterol 22:627 (+)-Diethyltartarate 6:264,268 L-(+)-Diethyltartrate 11:99,132,139 Dietyosphaeriafarulosa 25:898 DIF assay system 29:87 3 [3-acetoxy-8 [3-isobutyrylo xyreynosin activity in 29:87 rac- 1,2-Di-fattyacyi-3-mercaptoglycerol 18:841 5,5'-Diferulic acid 27:759 5,8'-Diferulic acid 27:759 8-O-4'-Diferulic acid 27:759 Diferuloylmethane 27:852 DiffQuick reagent 30:596 Differentiation 30:496 of human HL-60 leukemia cells 30:496 Difficidin 5:606,607 Difforlemenine 9:181 8',8'-Difluoro-abscisic acid 27:347 10,10-Difluoroarachidonic acid 9:551 2,4-Difluoroestradiol 5:451-453 Digalactosyl 1-thio analog 8:317 of ~,[3-trehalose 8:317 synthesis of 8:317 Digeminine A 12:477 from Tridedemnum species 12:477 Digenea simplex 25:846;26:478 Digestive organs motility accelerator 24:900 gingerol as 24:900 Diginatigenin 15:362 Diginatin 15:362 Digioxigenin-3-O-tridigitoxide 25:535
255
Digitalis 2:402,439;21:488;26:174 Digitalis glycosides 22:58 Digitalis lanata 15:367,375,377;25:535 Digitalis purpurea 14:439;25:535; 27:837 steroidal lactones from 14:439 digitoxin from 5:505;5:505 p-Digitatum 25:148,149 Digitolutein 26:806 Digitonin 2:54;25:308 Digitoxigenin 14:443-444,362 Digitoxin 5:505,439,362;21:488; 24:215,258-261 Diglucoside 25:200 Diglucuronate 15:26 Diglycosides 7:272,281,298 Digoxigenin 15:362 Digoxin 15:362;21:488 Digoxin-protein conjugates 15:366-368 Digydrosecurinine 21:69 0~,e0'-Dihalides 4:560-563 1,0~-Dihaloalkanes 6:313,314 ketones from 6:313,314 ct-Dihalomethylcycloheptanones 8:35 Dihalomethylithiation insertion 26:1221 matteson method for 26:1221 2,3-Dihdydroaromaticin 29:90 activity in NFkB assay system 29:90 (S)-(-)-9,10-Dihdyroxygeranylacetone 25:168 Diheptoses 4:196,206 in A eromonas hydrophila 4:196 in Neisseria meningitides 4:196,206 in oligosaccharide synthesis 4:204,205 24,24-Dihomo- 1c~,25-dihydroxy vitamin D3 11:385,386 pharmacological activity of 11:385,386 24,24-Dihomo-24-methylcholesta- 5,7diene-let,3[3, 25-triol 11:387,388 24,24-Dihomo-25-hydroxycholesterol 11:386 Dihydric phenolic lipids, cardol (1,3dihydroxy) type 30:121-137
occurrence of 30:121-122 structures of 30:123-137 Dihydric phenolic lipids, urushiol (1,2dihydroxy) type 117-118 occurrence of 30:117-118 structures of 30:117-118 Dihydro (A22,23) avermectin B l~ (ivermectin) 1:435 Dihydro alpha-agarofuran 25:171 Dihydro-~-agarofuran 23:663 basic skeleton of 23:663 14,15-Dihydro- 12-methoxyvincamine 5:126 20,21-Dihydro- 19-desoxomacroline 13:403,404 19,20-Dihydro- 19-hydroxycondylocarpine 1:40 1,2-Dihydro- 1-arylnaphthalene lignans 17:338 22,23-Dihydro- 1oc,25-dihydroxyvitamin D2 11:395-398 24R-epimer of 11:395-398 synthesis of 11:395-398 2,3-Dihydro-2,5-dihydroxy-6-methyl4H-pyra-4-one 21:674 2' o~-3' ct-Dihydro-2' cz,3 ' o~-epoxy-ABA 27:331 7,8-D ihydro-22 [3-hydroxytingenone 30:674 ~H-~H-COSY experiment of 30:674 ~H-NMR spectrum of 30:674 HMBC of 30:674 HMQC of 30:674 structure of 30:674 2,3-Dihydro-3(1-aziridinyl) withaferin A 20:245 6,7-Dihydro-3-[(3-guauiazulenyl) methylene]-8( 3H)-guaiazule ne 14:344 4,10-Dihydro-3H-naphtho [2,3-c] pyran10-one(yellow pigment) 11:127-129 (+)-nanaomycin from 11:127 synthesis of 11:129 (2R,3R)-2,3-Dihydro-5,7,3',4'tetrahydroxy-6-methoxy-3-Oacetylflavonol 15:32
256 (2R, 3R)-2,3-Dihydro-5,7,3',4'-tetrahydroxy-6-methoxy flavonol 27:17,35 structure of 27:35 (2R, 3R)-2,3-Dihydro-5,7,3',4'-tetrahydroxy-6-methoxy-3-O-acetylflavonol 27:17,35 structure of 27:35 (2R, 3R)-2,3-Dihydro-5,7,4'-trihydroxy6-methoxy-3-O-acetyl flavonol 27:18,35 structure of 27:35 4[3,6c~-Dihydro-5,7aH,8,11~Heudesma-8,12-olide 27:553 3,4-Dihydro-6,7-dimethoxy-isoquinoline 10:679-685 to chiral sulfoxides 10:679-685 to chiral sulfoximines 10:679685 3,4-D ihydro-6,7- dimethoxyisoquinoline-N-oxide 10:684 1,2-Dihydro-6c~-santonin 14:413 (1)-a-santonin from 14:413 7,8-Dihydro-7-oxo-22~hydroxytingenone 30:673 13C NMR of 30:672 DEPT of 30:672 HMBC of 30:672 HMQC of 30:672 Dihydro-8 a-hydroxybalchanin 24:77 9,10-Dihydro-9,10-dihydroxy anthracene 11:124 from anthraquinone 11:124 5,7,12,14-pentacenediquinone from 11:124 synthesis of 11:124 with acetoacetate dianion 11:124 2',3'-Dihydro-ABA 27:353 Dihydroactinidiolide 3:157,158 S-Dihydroaeruginoic acid 21:186 ~-Dihydro-agarofuran skeleton sesquiterpenes 18:775 Dihydroailanthinone 7:379,380 19,20-Dihydroakuammicine 1:32-35,54 2,16-Dihydroakuammicine 1:35 Dihydroalloevodionol 4:386,387 Dihydroalstonerine 13:398,423,424 20-21-Dihydroalstonerine 13:420-423
(+)-Dihydroanatoxin-A 13:493,494 Dihydroancyriacyanin A 12:367,372 fromArcyria nutans 12:367,372 Dihydroangustine 26:1036,1037 Dihydroanils 4:541,545 (+)- 18,19-Dihydroantirhine 14:706-708 (+)- 3 -ep i- 18,19-D ihydro antirhine 14:708 by alkaline decarboalkoxylative cyclization 14:708 from tetrahydropyridine 14:708 stereoselective 14:707,708 synthesis of 14:707,708 2,3-Dihydroapigenin 25:541 Dihydroarcyriaflavin A 12:377 Dihydroarcyriarubin B 12:366,372 Arcyria denudata 12:366,372 Dihydroarcyriarubin C 29:258 as bisindole alkaloid 29:258 Dihydroartemesinin 13:657;22:154; 26:832,833,834 19,20-Dihydroaspidospermatine 1:40 Dihydroastaxanthin diacetate 6:154 22,23-Dihydroavermectin (ivermectin) B! 12:8 from avermectin B~ 12:8 with Wilkinson's catayst 12:8 22,23-Dihydroavermectin B~ aglycones 1:443 conversion to milbemycins 1:443 22,23-Dihydroavermectin B ~b 12:17-19 aglycone of 12:17-19 Julia synthesis of 12:17-19 Dihydroavermectin B1~ 1:470 Dihydrobenzene 12:22-24 Dihydrobenzofuranols 14:651 synthesis of 14:651 via photocyclization of ketone 14:651 2,5-Dihydrobenzoic acid 23:91 Dihydrobetulinic acid 25:61 Dihydrobicyclomycin 12:65,66 16,17-Dihydrobrachycalyxolide 26:811, 812 Dihydrocaffeic acid 25:923,926 [26-3H]-Dihydrocalyesterol 9:44 [28-3H]-Dihydrocalyesterol 9:45
257
Dihydrocalysterol 9:36-38,41-45 from Calyx nicaeensis 9:37,44 from Cribrocalina vasculurn 9:37 from Petrosiaficiformis 9:37 from Petrosia hebes 9:37 20S- 1,2-Dihydrocapuvosidine 5:129 8,9-Dihydrocarotane sesquiterpene 5:728,729 Dihydrocarotol 5:734 Dihydrocarpalasionin 15:143,152, 160,174 (-)-Dihydrocarveol 29:83 activity in AM assay system 29:83 (R)-Dihydrocarvone 13:546 (+)-Dihydrocarvone 14:454;25:145, 146,147 5-epi-paradisiol from 14:454 (-)-Dihydrocarvone 5:721 d/-Dihydrocatharanthine 14:806,807,850-853 Dihydrocatharanthine 14:809,810 dihydrocatharanthinol from 14:809,810 synthesis of 5:182 15,20S-Dihydrocatharanthine N-oxide 14:870,871 decarbomethoxycatharanthine from 14:870,871 deoxyvinblastine from 14:870,871 16'-epi-deoxyvinblastine from 14:870,871 16'-epi-20'-epi-deoxyvinblastine from 14:870,14:871 vindoline-N-methylamide from 14:870,871 with vindoline 14:870,871 Dihydrocatharanthinol 14:810 from dihydrocatharanthine 14:810 3,14-Dihydrocellipticine 5:125 Dihydrocephalostatin 18:902-904 Dihydrochalcone 7:229,30,31;21:520, 522;28:234,271 aspalathin from 28:272 in apple juice 28:271 in cider 28:271
in pomace 28:271 nothofagin from 28:272 Dihydrochelerythrine 14:774,775,796 cyclization 14:774,775 from berberine 14:774,775,796 synthesis of 14:774,775,796 through enamide-aldehyde Dihydrochromones 20:282 (-)-Dihydrochrysanthemolactone 16:257-258 synthesis of 16:257-258 Dihydrocinchonamine 25:28 R-(+)-Dihydrocitronellic acid 15:231 Dihydrocitronellol 25:133 c~/[3-Dihydrocleavamine 14:806, 807,808,850,851,863,864 (-)-20S-15,20-Dihydrocleavamine 5:124 Dihydrocleavamine 5:181,182; 14:807,808 Dihydrocodeinone 18:96,98 Dihydrocompactin 13:580 19,20-Dihydrocondylocarpine 1:34 Dihydrocoptisine 6:491 ~x-Dihydrocomin 7:461 Dihydrocorphinol 9:602 Dihydrocorynantheine 22:19;25:31,32 Dihydrocorynantheol 13:92,93 (+)-Dihydrocorynantheol 18:331 Dihydrocostunolide 17:609 Dihydrocoumarin 7:205,206,225 Dihydrocubebin 17:318;26:191 (-)-Dihydrocubebin 5:753,754 23,24-Dihydrocucurbitacin F 25:59 Dihydrocurcumin 17:363 Dihydrocurecuquinone 5:767 Dihydrocycloakagerine 9:179 Dihydrocycloorbigenin 27:474 Dihydrocyclotheonamide A 26:1194, 1195,1196 Dihydrodaturalactone B 20:2462,3Dihydrodeoxyartemisinin 22:154 (+)-[3-A6-Dihydrodesoxycodeine methyl ether 18:65 Dihydrodesoxyotonecine 1:243 Dihydrodiconiferyl alcohol 27:760 polymerization of 27:760 Dihydrodidemnin 27:804 biological activity of 27:804
258 Dihydrodiisoeugenol 26:226 antibacterial activity of 26:226 11 [3,13-Dihydrodouglanin acetate 7:212,213 3,14-Dihydroellipticine 6:507,516, 518,519 Dihydroeperulic acid 25:248 Dihydroerysodine 3:478 dihydrofurans 3:55-58 from vinyloxiranes 3:55-58 synthesis of 3:478 (9S)-9-Dihydroerythromycin A 12:53,54 erthromycin A from 12:53,54 Dihydroerythromycin A 13:173-176 (9S)-9-Dihydroerythronolide A 12:53,54 ;16:718-719 erthromycin A from 12:53,54;16:718-719 erthronolide A from 12:48-53 (9S)-Dihydroerythronolide A 16:718-719 synthesis of 16:718-719 (9S)-Dihydroerythronolide A seco acid 3:478 synthesis of 3:478 Dihydroferulic acid 25:922-925 2,3-Dihydrofisetin 25:541 1ltx-Dihydroflabellin 27:579 1l~-Dihydroflabellin 27:579 Dihydroflavanoids 7:228;25:469 (+)-ampelosin 25:469 dihydromyricetin 25:469 Dihydroflavonols 15:30,31 ;22:312 Dihydroflavonol reductase 25:653 6,7-Dihydroflavopereirine 1:124,142, 143,150,153,157,158 5,6-Dihydroflavopereirine 26:1060 Dihydroflustramine C 18:691,725 Dihydroflustramine C N-oxide 18:691 Dihydrofolate reductase 7:387 Dihydrofreelingyne 15:235 Dihydrofumariline 1:198,199,207 Dihydrogambirtannine 1:158 oxidation to ourouparine 1:158 synthesis of 1:137 meso-Dihydroguaiaretic acid 26:191, 240,268,271
Dihydroguaiaretic acid 26:219,249,473 meso Dihydroguaiaretic acid 26:240 as PAF-induced inhibitor 26:240 nor-Dihydroguaiaretic acid 9:578,579 Dihydroguayaretic acid 773 Dihydrohalichondramide 17:16 11or,13-Dihydrohelenalin methacrylate 29:90 activity in NFAT assay system 29:90 activity in NFkB assay system 29:90 activity in CRO assay system 29:90 11c~,13-Dihydrohelenalin tigulinate 29:90 activity in NFAT assay system 29:90 activity in NFkB assay system 29:90 (+)- 18,19-Dihydrohunterburnine 14:706,707 (+)- 10-O-methyl- 18,19-dihydro hunterburnine from 14:706,707 synthesis of 14:706-708 with CH2N2 14:706,707 Dihydroindolizidine 11:241,243 6,7-Dihydroindolo [2,3-a] quinolizine 1:151 3,4-Dihydroisocoumarins 15:382 Dihydroisocoumarins 9:267,15:5,30, 31,381-418 Dihydroisodocarpin 15:141,149, 158,174 Dihydroisojacareubin 4:368,370 Dihydro-isokomarovine 14:762 from Nitraria komarovii 14:762 Dihydroisoosajin monomethyl ether 4:393,394 Dihydrojasmone 19:158,19:160 Dihydrojervine 23:575 Dihydrokaempferol 22:363 Dihydrokalafungin 11:128 Dihydrokamebakaurin aldehyde triacetate 15:135 Dihydrokawain 22:529,540 Dihydrokikumycin B 5:557,568 11-Dihydroklaineanone 23:301
259 Dihydrokoempferol 25:653 Dihydrokomarovinine 14:763,764 biosynthesis of 14:763,764 1,2-Dihydrokoumine 15:476 from Gelsemium elegans 15:476 5,6-Dihydrolamellarin H 23:248 Dihydrolanosterol 8:365,366 Dihydrolanosterol ester 9:467 Dihydrolevoglucosenone 14:278 Dihydrolicoisoflavone A 28:243 anti-Helicobacter pylori activity of 28:243 (+)-Dihydrolimonene 6:541,542;8:227 ozonization of 6:541 (-)-periplanone-B from 6:541, 542 2,3-Dihydroluteolin 25:541 3,4-Dihydromanzamine A 21:260, 261,262 Dihydromarthasterone 7:289;15:51 Dihydromethysticin 22:529,540 Dihydromevinolin 13:575,608,609 synthesis of 13:575,608,609 3,4-Dihydromilbemycin E 16:659 from Streptomyces sp. 16:659 Dihydromyoporone 1:604,606 9-Dihydromyoporone 15:229 7S,9R-(-)-9-Dihydromyoporone 15:230 Dihydronapthalenes 24:743,744,765 from oxidative coupling 24:743, 744 of 2,3-dibenzylbutyrolactones 24:744-754 synthesis of 24:765 Dihydronepetalactone 7:477;16:289 (+)Dihydronepetalactone 20:71 3,6-Dihydronicotinic acid 11:206 Dihydronitidine 14:775,776 Dihydronitraraine 14:765 from (S)-glyceraldehyde 14:765 synthesis of 14:765 2,3-Dihydro-N-methylacronycine 13:359 Dihydronodularin 9:496 from nodularin 9:496 (+)-7,8-Dihydronogarene 14:68 7,8-Dihydronogarene 14:78 Dihydronorfluorocurarine 1:46-48 22-Dihydrooccelasterol 9:41
Dihydro-O-methylmacusine B 13:387 Dihydroonychine 2:442 Dihydroparfumidine 1:206-209 Dihydroparthenolide 27:565 Dihydropenicillic acid 26:449 Dihydroperaksine 13:387 Dihydroperezine 5:766,767 Dihydroperillic acid 29:83 activity in RAS assay system 29:83 Dihydroperoxides 9:560 5,6-Dihydro-PGI2 25:595 Dihydrophenanthrenes 20:280 Dihydrophenanthridines 4:541 Dihydrophenoxazine 26:976 Dihydrophymaspermones 15:233 (25S) 25,27Dihydrophysalin A 20:189 Dihydropinidine 1:391,392 (+)-Dihydropinidine 14:572,573 (-)-Dihydropinidine 16:482 2,3-Dihydropiperidine 19:45 Dihydroprotoberberines 14:771-773 Hofmann degradation of 14:771-773 (+)-Dihydroprotoemetine 18:330 (+)-20R- 18,19-Dihydropseudovincadifformine 5:124 Dihydropseurata F 15:117,124,131,174 Dihydropyran 12:158 Dihydropyran derivative 10:425 Dihydropyranocoumarins 18:984 Dihydropyridine receptor 21:17 Dihydropyridines 1:91,92;25:534 Dihydropyridinium 21:308 Dihydropyrrole 10:112,113 synthesis of 10:112,113 2,3,-Dihydroquercetin 25:541 (2R,3R)-Dihydroquercetin (toxifolin) 5:496 Dihydroquercetin 3-acetate 4'-(methyl ether) 15:26 (+)-Dihydroquercetin 3-O-acetate 15:31 Dihydroquercetin 3-O-acetate 4'-methyl ether 27:17,35 structure of 27:35 (2R, 3R)-Dihydroquercetin 3-O-acetate 27:17,34,35 structure of 27:35 Dihydroquinone uncinatone 7:408,423
260
Dihydroridentin 27:567 Dihydrorugosanin 15:142,150,159,174 Dihydrosampangine 23:35 Dihydrosanguinarine 14:793-795 from coptisine 14:793-795 structure of 27:173 synthesis of 14:793-795 through cationic cyclization 14:793-795 bis( 6-Dihydrosanguinarinyl) ether 27:172 bond length & angles in 27:175 crystal data of 27:175 structure of 27:172 X-ray analysis of 27:174 11or,13-Dihydrosantamarin 7:213 1,2-Dihydrosantonin 26:463 Dihydroschelhammeridine 3:484-486 synthesis of 3:484-486 6',7'Dihydro-scutionin ctB 30:685,686CD-spectrum of 30:685 structure of 30:686 Dihydrosecodine 19:90 15,20-Dihydrosecodine 19:91 Dihydrosecurinine 14:657 Dihydroserratenone 11:309 Dihydrosiphonarin A and B 17:25 Dihydrosirohydroochlorin 9:603 Dihydrosolanidine 23:575,584 Dihydrosolasodine 23:575,585 Dihydrosphingosine 18:786 Dihydrospiniferin-1 derivative 6:72 by Birch reduction 6:72 by electrocyclic rearrangement 6:72,73 by Jones oxidation 6:72 by Simmons-Smith cyclopropanation 6:72 from 6-methoxy-l-tetralone 6:72 Marshall synthesis of 6:72,73 Dihydrostemmdenine acetate 1:49 19,20 (-)-11,12-Dihydrostepharine 2:254,258 (+)- 8,9-Dihydrostepharine 2:254,258 20,21-Dihydrostrychnobrasiline 26:1065 Dihydrosweroside 26:104 8,10-Dihydrosweroside aglucone 26:141
20'S- 19',20'-Dihydrotabemamine 5:128 Dihydrotachysterol 4:521-526 synthesis of 4:521-526 Dihydrotanshinone 22:175 (11R)-I 1,13-Dihydrotatridin A 27:571 (11R)-I 1,13-Dihydrotatridin B 27:571 Dihydroteugin 23:609 Dihydrothebainone 18:59 (+)-Dihydrothebainone 18:70,72,73, 77,78 Dihydrothiopyrans 8:207 Dihydrothiopyrone 8:207,208 synthesis of 8:207,208 Dihydrotubastrine 5:360 Dihydroudoteal 18:688 3,4-Dihydroumbelliferone 4:400 12,13-Dihydroursolic acid 9:293,294 5',6'-Dihydrousambarensine 26:1062, 1063 anticancer activity of 26:1060 18,19-Dihydrousambarine 26:1062 anticancer activity of 26:1060 ot-Dihydroverbenol 7:461,462,467,468 Dihydrovincarpine 1:124 Dihydrowisanine 24:704 2,3-Dihydrowithaferin A 20:181, 194,214 Dihydroxanthommatin 26:988,989 3',4'-Dihydroxiflavone 26:757 Dihydroxy phenolic lipids 30:116 umshiol-type 30:116 1ct-25-Dihydroxy-(24R)-fluorocholecalciferol 10:57,69 3,6-Dihydroxy- 1,7-dimethoxyxanthone 30:622 3c~,13-Dihydroxy- 11-epi-apotrichotec-9ene 9:210 3[3,13-Dihydroxy- 11-epi-apotrichotec-9ene 9:210 2ct, 13-Dihydroxy- 11-epiapotrichothecene 13:520 2[3-13-Dihydroxy-11-epiapotrichothecene 13:520 10-Dihydroxy- 11-methoxydracaenone 5:17,18,20,22,556 ent- 12or,16-Dihydroxy- 13 [R]-imar8(14)- ene-3,15- dione 9:283,284
261
1,3-Dihydroxy-2-( 1'-oxotetradecyl)benzene 30:133 struture of 30:133 3,4'-Dihydroxy-2,3'-bipyridine 2:239,753 1,5-Dihydroxy-2,3-dimethoxy- 10methylacridin-9-one 13:348,350,355 from Glycosmis bilocularis 13:348,350,355 synthesis of 13:354,355 (2S)-2,4' Dihydroxy-2"-( 1-hydroxy- 1methylethyl)-dihydrofuro[2,3h]flavanone 28:17 as aromatase inhibitor 28:17 20,22f3-Dihydroxy-20-epi-tingenone 30:669 20,21 a-Dihydroxy-22-oxo-21desoxotingenone 30:669 NMR experiments of 30:669 NOE experiments of 30:669 structure of 30:669 2,3-Dihydroxy-24-norfrieadela-l,3,5,7 tetraen-29-oic acid 25:59 diacetoxy derivatives 25:59 (22R,23 R,24 S)-22,23-D ihydroxy- 28homoergosterol 18:520 2,4-Dihydroxy-2H- 1,4-benzoxazin3(4H)-one-skeleton 27:194-196 1,3-D ihydro xy-2-he xadec ylb enzene 30:129 structure of 30:129 1,3-Dihydroxy-2-hexyl-5-pentylbenzene 30:137 structure of 30:137 4,4'-Dihydroxy-2-methoxy-5-(c~,otdimethylallyl)-chalcone 21:741 1,3-Dihydroxy-2-methyl-5tridecylbenzene 30:126 structure of 30:126 (22 R, 23 R,24 R)- 22,23-D ihydroxy2~,3 c~-epoxy-24-methyl-5 ~cholestan-6-one 18:512 2,13-Dihydroxy-3,11-epoxy APO 13:522 6 a,25-Dihydroxy-3,16-dioxo-9fl,19cyclolanestane 25:184
213,2213-Dihydroxy-3,21-dioxo-24carboxyl-29-nor-ffiedelan methyl ester 30:641 structure of 30:641 4,5-Dihydroxy-3,3,6, 7,8pentamethoxyflavone 30:742 (R)-2,4-Dihydroxy-3,3-dimethylbutanoic acid 10:442,443 5,3-Dihydroxy-3,6,7,4',5'-pentamethoxyflavone 5:757 1,3-Dihydroxy-3,7-dimethytoct-6-ene-2one 25:134 3 [3,20~-Dihydroxy-30-novolenan- 12-en28- oic acid 7:139,140 1,5-Dihydroxy-3-methoxy- 10methylacridin-9-one 13:348,350 2 ',5 '-Dihydroxy- 3-nitrophenylac etic acid 26:592 2c~,19c~-Dihydroxy-3-oxo- 12-ursen-28oic acid (ursane triterpene) 29:574 effects on HIV-1 protease 29:574 4c~,10~-Dihydroxy-3-oxo-8 []-isobutyryloxyguaia- 11(13)-en- 12,6c~-olide 29:90 2,2213-Dihydroxy-3-oxo-olean- 1,12dien-29-oic acid 30:651 13C NMR spectrum of 30:650 IH NMR spectrum of 30:650 HMBC spectra of 30:650 molecular formula of 30:650 structure of 30:651 ent- 13 [S], 14 [S]-Dihydroxy-3-oxo-tis- 15en-17-al 9:268,269,276 1,2-Dihydroxy-3-pentadecyl benzene 9:314,318,343 6,8-Dihydroxy- 3-undec yl-3,4dihydroisocoumarin 15:386 3,6-Dihydroxy-4,5,7-trimethylmellein 15:385 2,6-Dihydroxy-4-methoxyacetophenone 4:386,387 1,3-D ihydroxy- 5- (2 '-hydro xy- 8 'oxotridecyl)benzene 30:131 structure of 30:131 10S, 11R-Dihydroxy-5 (6), 15-rosanedien7-one 20:474
262
1,3-Dihydroxy-5-(nonadec-8Z, 11Zdienyl)benzene 30:125 structure of 30:125 1,3-Dihydroxy-5-(none-2Z-enyl)benzene 30:124 structure of 30:124 3,6-Dihydroxy-5,7-dime thylmellein 15:385 4[3,6c~-Dihydroxy-5,7 c~H,813Heudesman-8,12-olide 27:552 3,10-Dihydroxy-5,8-diacetoxy- 1(2), 1 l(12)-dehydrofamesol 27:586 1,3-Dihydroxy-5 -alkylbenzenes 9:320,321 1,3-Dihydroxy-5-heneicosyl benzenes 9:343 1,3-Dihydroxy-5-hexyl-2-propyl benezene 9:322 1,3-Dihydroxy-5-isotetradecylbenzene 30:130 structure of 30:130 1,3-Dihydroxy-5-nonadecyl benzene 9:343 1,3-Dihydroxy-5-pentyl benzene (olivetol) 9:344 1,3-Dihydroxy-5-tridecyl benzene 9:344 1,3-Dihydroxy-5-tridecyl benzene from 9:344 313,6c~-Dihydroxy-5c~-pregn-9(11)-en20-one 7:156,157;15:45 2o~,313Dih y dro x y- 5 et-pre gnane-6,20dione 18:530,18:534 2,4-Dihydroxy-6-(1-oxooctyl)benzoic acid 30:134 structure of 30:134 5,4'-Dihydroxy-6,7,3'-trimethoxyflavone 5:653,655 5,4'-Dihydroxy-6,7,8,3'-tetramethoxyflavone 5:653,5:655 5,4'-Dihydroxy-6,7,8-trimethoxyflavone 5:653 3,4,'-Dihydroxy-6,7-dimethoxyflavone 5:14,15 5,8-Dihydroxy-6,7-dimethoxyflavone 5:624,627,628,640 5,4'-Dihydroxy-6,7-dimethoxyflavone 5:653,657
213,413-Dihydroxy-6-deoxy-celorbicol 18:744 5,7-Dihydroxy-6-methoxyflavonoid 5:640 11,12-Dihydroxy-6-oxo-8,11,13abietatriene 29:99 activity in COX assay system 29:99 1[3,4c~-Dihydroxy-6a-angeloyloxyeudesm- 11(13)-en-8,12-olide 27:552 113,4c~-Dihydroxy-6o~-isobutyloxyeudesm- 11 (13)-en-8,12-olide 27:552 5,6-Dihydroxy-7,3',4'-trimethoxyflavone 5:655 5,6-Dihydroxy-7,4'-dimethoxyflavone 5:623,653 5,6-Dihydroxy-7,8,3',4'-tetramethoxyflavone 5:655 5,6-Dihydroxy-7,8,4-trimethoxyflavone 5:629,653 15c~,22[3-Dihydroxy-7,8-dehydrotingenol 30:682 ~3C-NMR data 30:682 structure of 30:682 7,8-Dihydroxy-7,8-dihydrobenzo [ 1] pyrene 9:583 7,8-Dihydroxy-7,8-dihydro-vitamin D2 9:522 5,6-Dihydroxy-7,8-dimethoxyflavone 5:624-629,640 9,10-Dihydroxy-7-methoxynaphtho [2,3-c] pyran-l(1H)-one (semivioxanthin) 11:130 antibiotic activity of 11:130 antifungal activity of 11:130 1[3,3[3-Dihydroxy-7ot, 11 [3H-germacra4Z- 10(14)-dien-12,6ct-olide 27:562 1,3[3-Dihydroxy-7a, 11 [3H-germacra4Z,9Z-dien- 12,6o~-olide 27:562 1a,3 [3-Dihydroxy-7c~, 11 [3H-germacra4Z,9Z-dien- 12-6c~-olide 27:561 5,11-Dihydroxy-8,9-dihydro-9,10dehydronerolidol 27:587 2o{,4[~-Dih ydro xy- 8-ep i-cel apano I 18:746
263
5,7-Dihydroxy-8-methoxyflavonoid 5:640 1c~,313-Dihydroxy-9[3,10[3-epoxy7a, 11 [3H-germacra-4Z-en- 12,6o~olide 27:562 7(x, 15-Dihydroxyabieta-8,11,13-trien18-al 29:99 activity in EBV assay system 29:99 from Larix kaempferi 29:99 15,18-Dihydroxyabieta-8,11,13-trien-7one 29:99 activity in EBV assay system 29:99 18-nor-4ct, 15-Dihydroxyabieta-8,11,13trien-7-one 29:99 activity in EBV assay system 29:99 15,18-Dihydroxyabieta-8,11,13-trien-7one-18-acetate 29:99 activity in EBV assay system 29:99 2~-23-Dihydroxyacacic acid 21:643 1,3-Dihydroxyacridin-9-one 13:355,358 9,11-Dihydroxyacronycine 13:366,367 (+)-3,9-Dihydroxyaporphine 16:518 ent- 13 IS], 15 [3-Dihydroxyatis- 16-ene3,14-dione 9:268,269 ent- 13 [S], 18Dihydroxyatis- 16-ene-3,14ione 9:268,269,276,282ent-3 [3,13[S]-Dihydroxyatis-6-ene- 14one 9:268,269,276,280 ent- 16c~,17-Dihydroxyatisan-3-one 9:68,269,276,9:277,168,169,176 1,3-Dihydroxybenzene 14:655 dichlorination of 14:655 with sulfuryl chloride 14:655 3,4-Dihydroxybenzoate 22:322 2,5-Dihydroxybenzoic acid 21:617 2,4-Dihydroxybenzoic acid 2,4-Dihydroxybenzoic acid 4:395,398; 21:7412 Dihydroxybenzoic acid 26:337 2,5-Dihydroxybenzyl 27:870 for inhibitory activity 27:870 2ot,3 [3-Dihydroxy-B-homo-6a-oxa-5etpregnane-6,20-dione 18:530
1ot,25-Dihydroxycalciferol (calcitriol) 9:20,521 Dihydroxychalcones 22:420 1et-25-Dihydroxycholecalciferol-26,23 (S)-lactone 10:59 synthesis of 10:59 20,22-Dihydroxycholesterol 21:309 Dihydroxychromone 21:147 3,4-Dihydroxycinnamate 22:322 Dihydroxyconiferyl-alcohol 25:657 6,7-Dihydroxycoumarin 27:847 7,8-Dihydroxycoumarin 27:847 7,8-Dihydroxycoumarin 4:372,373 3 [3,29-Dihydroxy-D: f3-frie do- o lean- 5ene 5:747 2c~,14-Dihydroxydehydroabietic acid 20:669 Dihydroxyethylated rutoside 22:320 (S)-(-)-I 0,11-Dihydroxyfarnesol 25:166 5,4'-Dihydroxyflavone 25:541,544 5,7-Dihydroxyflavone 25:541,544 3,2'-Dihydroxyflavone 29:572 effects on HIV- 1 protease 29:572 5,8-Dihydroxyflavonoid 5:625,627, 628,658 5,6-Dihydroxyflavonoid 5:625627,629,658 3,4-Dihydroxyflavonoid aroxyl 22:322 5,8-Dihydroxyflavonols 5:627 28,29-Dihydroxyfriedelan-3-one 7:150 1,4-Dihydroxy- germacra- 5E- 10( 14)diene 29:88 activity in CRO assay system 29:88 Dihydroxyheliotridane 1:246,252, 253,52 synthesis of 1:246,252,253,52 1,2-Dihydroxy-hexahydro-3 ( 2H)indolidinones 12:305 3,4-Dihydroxyhomoisoflavan 5:21,22 1,2-Dihydroxyindolizidine 12:303-306 (+)-( 6R,7S, 8aR)-Dihydroxyindolizidine 12:306 6,7-Dihydroxyindolizidine 12:348 from methyl 2-azido-4,6-Obenzylidene-2-deoxy-c~-D-
264 altropyranoside 12:348 synthesis of 12:348 Dihydroxyindolizidine 27:525 from natural sources 27:525 1tx,6c~-Dihydroxyisocostic acid methyl ester 27:557 5,7-Dihydroxyisoflavone 4:382,385 4'-O-methylosajin from 4:382,385 4'-O-methylwaranglone from 4:382,385 with 3,3-dimethylallyl bromide 4:382 14,15[3-Dihydroxyklaineanone 23:301 6,7-Dihydroxylate coumarin 5:516, 517,520 Dihydroxylation 11:423,424 cis-Dihydroxylation 16:332 of AZZ-stigmasterol 16:332 of brassicaterol 16:332 of ergosterol 16:332 (-)-3,13 a-Dihydroxylupanine 15:523 from Cytisus scoparius 15:523 15 2,5-Dihydroxymethyl-3,4dihydroxypyrrolidine(DMDP) 7:13 2R,5R-Dihydroxymethyl-3R,4Rdihydroxypyrrolidine 10:545,546 absolute configuration of 10:545,546 almond emulsin D-glucosidase inhibitor of 10:545 enantioselective synthesis of 10:546,547 from Derris elliptica 10:545 from Lonchocarpus sericeus 10:545 from Omphalea diandra 10:545 [3-galactosidases 10:545 [3-glucosidases 10:545 insect trehalase inhibitor of 10:545 relative configuration of 10:545,546 yeast invertase inhibitor of 10:545 yeast ot-glucosidase inhibitor of 10:545 2-Dihydroxymintlactone 26:456
3,11-Dihydroxymyristic acid 13:312 1,8-Dihydroxynaphthalene 21:208 10,11-Dihydroxynerolidol 25:163 (6R,7R)-6,7-Dihydroxynonan-2-one 11:413,414 3c~,28-Dihydroxy-olean-12-en-29-oic acid 30:649 3 [3,28-Dihydro xy-o lean- 12-en-29-o ic acid 30:649 6,5-Dihydroxyperezone 5:795,796 Dihydroxyphenolic compounds 25:657 L-3,4-Dihydroxyphenylalanine 27:754 from peroxidase 27:754 D-(-)-3,4-Dihydroxyphenylglycine 27:754 from peroxidase 27:754 3,4-Dihydroxyphenyllactic acid 30:216 3 [3,4~-Dihydroxypregn-5-en-20-3sulfate 28:704 5-pregnene skeleton of 28:704 20R- 18,19-Dihydroxypseudovincadifformine 9:190 Dihydroxyserrulatic acid 15:257 from Eremophila serrulata 15:257 3,11-Dihydroxystaurosporine 12:366,370 fromEudistoma sp. 12:366,370 (22R,23R)-22,23-Dihydroxystigmasterol 18:515 Dihydroxythymoquinone 5:776 20,2213-Dihydroxytingenone 30:669
8ct,9~-Dihydroxy-trans,trans-germacra1(10),4(5)-dien-trans-6,12-olide 27:563 14,15-Dihydroxyvincadifformine 5:124 l(x,25-Dihydroxyvitamin D 30:485 structures of 30:485 1,24-Dihydroxyvitamin D2 9:513 1,25-Dihydroxyvitamin D2 9:513 24,25-Dihydroxyvitamin D2 9:513 24,26-Dihydroxyvitamin D2 9:513 25,26-Dihydroxyvitamin D2 9:513 1c~,25-Dihydroxyvitamin D2 (ercalcitriol) 11:393-395 synthesis of 11:393-395 24R-epimer of 11:393-395
265
1Gt,24R-Dihydroxyvitamin D3 11:384,385 synthesis of 11:384,385 1c~,24S-Dihydroxyvitamin D3 11:384,385 synthesis of 11:384,385 1c~,25-Dihydroxyvitamin D3 9:12,514, 516,519;11:379,380,385,395 ;20:669; 30:484 effect on bone maturation 30:484 effect on calcium metabolism regulation 30:484 effect on immune responsiveness 30:484 effect on malignant cells differentiation 30:484 synthesis of 11:384,385,388-423 24R,25-Dihydroxy-vitamin D3 9:512, 514 6tx,7[3-Dihydroxyvouacapan-1713-oic acid 29:103 activity in AOS bioassay system 29:103 1,3-Dihydroxyxanthone 22:664,665 1,7-Dihydroxyxanthone 5:759 2,3-Dihydroxyxanthone 5:759 Dihydroyashabushiketol 26:883 Dihydroyohimbine 15:487 3,4-Dihydro-[3-carboline 13:489,490 Dihydro-13-carboline 8:287,288 Dihydro-[3-cyclo-pyrethrosin 27:554 Dihydro-[3-erythroidine 21:52 20R- 1,2-Dihyrocapuvosidine 5:123125,127,131,129 (+)-20R-15,20-Dihyrocleavamine 5:124 3,8-Dihyroxy-gluco side-2hydroxymethy lanthraquinone 26:657 3,5-Diidotyramine 23:234 Diindole 12:382,383 3'-7,y-Diinethylallylwighteone 25:541 3,5-Diiodo-L-tyrosine 10:653,661,667 Diisobutyl aluminum hydride (DIBAL-H) 1:523,324,353;4:589, 590;22:203,226,228 Diisobutylaluminium 6:115 Diisobutylaluminum hydride-Nbutyllithium "ATE"complex 14:595
7,20-Diisocyanoadociane 21:330 Diisocyanoadociane 21:350,367 7,20-Diisocyanoadociane 6:86,87 by intramolecular [4+2] cycloaddition 6:86,87 by stereospecific intramolecular Diels-Alder cycloaddition 6:86,87 by vinylation 6:86,87 by Wittig coupling 6:86,87 enantioselective synthesis of 6:86,87 fromAdocia species 6:86 from (1R,2S,5R)-(-)menthol 6:86 (+)-Diisopinocamphenylborane 20:587 Diisopropyl (bromomethyl) boronate 11:425 synthesis of 11:425 Diisopropyl aprotinin 30:836 N,N-Diisopropyl carbamoyl chloride 10:15 Diisopropyl ethanediol esters 11:415417 insect pheromones II from 11:415-417 Diisopropyl fluorophosphase (DFP) 30:843 Diisopropyl tartarate 12:282,19:445 3,7-Diisopropyl- 1-azulenecarbaldehyde 14:337,340 Diisopropylamine 12:113 Diisopropylamine borane 4:437 in stereoselective reduction 4:437 Diisopropylethanediol (DIPED) 11:415 (S,S)-Diisopropylethanediol methyl boronate 11:415,416 ( R, R )-D iisoprop yl e thanedi o l
propylboronate 11:415 Diisopropylethylamine 12:46,47 N,N-Diisopropylphosphoramidites 18:398 1,4-Diisothiocyanatobenzene 26:481 [3-Diketone 6:48 in (+)-A9<~Zkcapnellene synthesis 6:48 photochemical annulation of 6:48
266
c~-Diketone 8:165,166 synthesis of 8:165,166 1,3-Diketone enolates 3:74,75 1,4-Diketones 6:437,438 2,5-dialkyl pyrrolidines from 6:437,438 reductive amination of 6:437,438 Diketopiperazines 10:638,96,97,321; 21:310,323,218,221 ;25:901 ;28:362 containing dioxepinoindole ring 28:362 2,2'-Diketospirilloxanthin 20:594 Dilactone 6:301,303 synthesis of 6:301,303 Dilactonic clerodane-diterpene 30:748 Dilaspiralactone 4:712 Dilignan 5:497,498 Dilignols 5:464-466 Dilithium (cyano) dimethyl cuprate 11:361 Dilithium (cyano) divinyl cuprate 11:360,361 Di-/-menthol (acetoxymethylene) malonate 13:66 Dilodia gossypina 25:131,149 Dilophus 25:690 Dilophus ligulatus 25:690 Dilophus okamurai 25:690 DIMBoA 27:213,214 in tritrophic interaction 27:213, 214 Dimeric anthracenones 22:557 Dimeric aporphine 30:584 Dimeric coniferyl alcohol derivatives 27:592 Dimeric tetrahydroisoquinolines 21:57 Dimeric triterpenes 18:764-709 Dimerization 26:532 of resveratrol 26:532 Dimers 26:544,545,546,547,548,549 ampelopsin D&F 26:544 anigopreissin A 26:544 betulifol A&B 26:545 gnetin A&C 26:546 gnetin F&G 26:546,547 leachianol G 26:547 malibatol A 26:547 parthenocissin A 26:548 restrytisol A-C 26:548,458
tricuspidatol A 26:549 viniferifuran 26:549 (+)-e-viniferin 26:545 Dimethomorph 9:226 1,3-10,11-Dimethoxy indolines 9:185,186 1R- 1-Dimethoxy phosphenyl-D-threitol 6:355 3,3-Dimethoxy- 1-(phenylsul fonyl)propane 30:470 (+)-(2R,3 R)- 1,4-Dimethoxy-2,3butanediol 14:499,14:500 1,4-Dimethoxy-2,4 ',4"- trihydrox y-pterphenyl 29:267 as cytotoxic principle 29:267 2-( 4,5-Dimethoxy-2-nitrobenzyl)20-hydroxyecdysone 29:19 as synthetic ecdysteroid analogues 29:19 3,4 '-Dimethoxy-3 ', 5,7trihydroxyflavone 30:728 structure of 30:728 2,4-Dimethoxy-3-methyl-phenol 13:437,438 1,2-Dimethoxy-4-(E-3'-methyloxiranyl) benzene 26:362 2,6-Dimethoxy-4-hydroxyacetophenone 4:386,387 2,3-Dimethoxy-4-pyridyl-N,Ndiisopropyl carbamate 21:214 Dimethoxy-5-(7-hydroxyheptyl)benzene 9:345 1,3-Dimethoxy-5-( 9-phenylnonyl)benzene 30:135 structure of 30:135 1,3-Dimethoxy- 5- (unde c- 3Zenyl)benzene 30:127 structure of 30:127 3,4- Dime thoxy-6-(2'N,N-dimethylaminoethyl)-5-(methylthio)benzotrithiane 25:833 2,12-D imetho xy-6,7,8,9-tetrahydro- 5-Hdibenz [d,f] azonine-3,11-diol 6:478 synthesis of 6:478 Dimethoxyabieta-8,11,13-triene 14:676, 677 demethoxylation of 14:676,677 to taxodione 14:676,677 transformation of 14:676,677
267 Dimethoxyabietatriene 14:697,698 10,11-Dimethoxyacronycine 20:792, 798 5,7-Dimethoxyanthracene 11:120 Dimethoxyanthracene 11:126 Claisen condensation of 11:126 5,5'-dipentacene 14,14' (5H,5'H) dione from 11:126 with methyl acetoacetate dianion 11:126 with Pb (OAc)2 11:126 Dimethoxybenzaldehyde 9:343,354 Dimethoxybenzene 14:670-674,681,682 1,3-Dimethoxybenzene 4:389 3,4-Dimethoxybenzoic acid 26:1013 3,5-Dimethoxybenzoic acid 9:344 2,6-Dimethoxybenzoquinone 23:341,797 3,5-Dimethoxybenzoyl chloride 9:344 N-(2,4-Dimethoxybenzyl) tirandamycin 14:138 (-)-trans-2-( 3 ,4-Dimetho x ybenzyl )- 3(3,4-methylene-dioxybenzyl)T-butyrolactone 18:556 4,4-Dimethoxybutyronitrile 6:319 1,11-Dimethoxycanthin-6-one 7:389,390 10-11-Dimethoxycoronaridine (conopharyngine) 9:174,176,177 (2R)-5,6-D imetho xydehyrois o-cxlapachone 20:494 Dimethoxyethane (DME) 8:16,166 6', 8'-Dimethoxyfeselol 27:592 5,7-Dimethoxyflavone 5:413,652 3,5-Dimethoxyfluorobenzene 9:346 ix,ct-Dimethoxylation 3:474 1,8-Dimethoxynaphthalene glutarate 11:120 Dimethoxyolivetol 19:187 3,4-Dimethoxyphenethyl alcohol 12:448 3,4-Dimethoxyphenol 8:170 anodic oxidation of 8:170 (3,4-Dimethoxyphenyl) methyl methyl ketone 6:334 from veratraldehyde 6:334 methyl-DOPA from 6:334
8-(3,5-Dimethoxyphenyl) octan- 1-ol 9:339 synthesis of 9:339 2-( 3',4'-Dimethoxyphe nyl)- 1,3-thian 12:466 3,4-Dimethoxyphenylacetone 30:219 condensation of 30:214 reactions of 30:219 2,3-Dimethoxyphenylethanal 30:215, 216 3,4-Dimethoxyphenylethanal 30:215 3,4-Dimethoxyphenyl- O-D-glucoside 27:410 3,4-Dimethoxyphenylpropionic acid 12:448 3,4-Dimethoxypyridine 21:214 2,5-Dimethoxytetrahydrofuran 19:18,19 2,6-Dimethoxytoluene 13:437,438,448 Dimethoxytrityloxyethylsulfonylethyl 4:285 Dimethyl (methylthio) sulfonium triflate (DMTST) 10:467 Dimethyl 2-amino- 1,3-azulenedicarboxylate 14:339 Dimethyl 2-amino-6-formyl- 1,3azulenedicar-boxylate 14:339 Dimethyl 3,5,10,13-tetraoxotetra decanedioate 11:116 Dimethyl 6-substituted 3,5,9,11tetraoxodo-decanedioatel 1:118 Dimethyl azodicarboxylate 22:211 3,5-Dimethyl benzylalcohol 9:225 2,2-Dimethyl chromanes 9:115,116 Dimethyl diazene 22:196 Dimethyl ketal 11:347 2',6'-Dimethyl L-tyrosine (Dmt ~) 30:801 Dimethyl N-boc-threo-f3-hydroxy-Lglutamate 12:431,432 Dimethyl phosphorochloridite 18:399402 Dimethyl polysiloxane 9:454,456 (R, R)-2,5-Dimethyl pyrrolidine 14:555,556 Dimethyl sulfoxide (DMSO) oxidation 10:413,414 4,4-Dimethyl thiazolidin-2-thione derivative 12:164,166 Dimethyl thiosulfinate 23:467
268
3,7-Dimethyl-(E)-2,6-octadien-l-ol 25:132 4,6-Dimethyl- 1,3-cyclohexadiene 6:83,84 2,8-Dimethyl- 1,7-dioxaspiro [5.5] undecane 1:692 3,7-D imethyl- 1,7-octanedio1 25:133,136 2,6-Dimethyl-l,8-octanediol 25:135,138 12,7-Dimethyl- 1,1,6-dioxaspiro [4.4]nonanes 19:129 1,2-Dimethyl- 1-carboxymethyl-2-phenyl cyclopentane 8:13 6,7-Dimethyl- 1-hydroxyxanthone 5:759 4,4-Dimethyl- 1-mesityl-2-pentyn- 1-one 14:615 1,2-Dimethyl- 1-phenyl cyclopentane 8:6,7 cis- 1,2-Dimethyl- 1-phenyl cyclopentane 8:8 trans- 1,2-Dimethyl- 1-phenyl cyclopentane 8:8,9 4,7-Dimethyl-2-(4,6,, 8-trimethyl- 1azulenyl)- 1H-inden- 1-ones 14:342 (2E,5 E)-3,7-Dimethyl-2,5-octadiene1,7-diol 25:138 (Z)-2,6-Dimethyl-2,7-octadiene- 1,6,-diol 25:138,142 (E)-2,6-Dimethyl-2,7-octadiene- 1,6,diol 25:142,138 1,3-Dimethyl-2-arylnaphthalenes 30:217 3,5-Dimethyl-2-cyclohexan- 1-one 6:82,83 (+)-9-isocyanopupukeanane from 6:82,83 5,5-Dimethyl-2-cyclpentenone 13:16 (Z)-2,6-Dimethyl-2-octene- 1,8-diol 25:136 (E)-2,6-Dimethyl-2-octene- 1,8-diol 25:138 (Z)-3,7-Dime thyl-2-octene- 3,8-dio1 25:138 (E)-3,7-Dimethyl-2-octene-l,8-diol 25:138 4,4-Dimethyl-2-oxazolidone derivative 12:164,166
1,3-Dimethyl-2-oxohexahydrop yrimidine 8:316,343 1,3-Dimethyl-2-phenylnaphthalene skeleton 30:219 2,5-Dimethyl-3-(1-hydroxyisopentyl)-6(1-oxoisopent-2-enyl)-pyrazines 5:227,247,266 2,5-Dimethyl-3-( 1-oxoisopentyl)- 6-( 1hydroxyisopentyl)-pyrazines 5:226,246,247,266 2,5-D imethyl-3-( 1-oxoisopentyl)- 6-( 1oxoisopent-2-enyl)-pyrazinesm 5:226,247,266 2,5-Dimethyl-3-(2-methylbutyl)pyrazines 5:224,228,230,231,243, 244,259,260 2,5-Dimethyl-3,6-di(1-hydroxyisopentyl) pyrazines 5:226,246,247 2,5-Dimethyl-3,6-di-(1-oxoisopentyl) 5:226,246,247,266 2,5-Dimethyl-3,6-diisopentylpyrazine s 5:225,227,229,246 2,5-Dimethyl-3,6-dimethylpyrazines 5:225,227,236 (2S*,3S*,6R*) 2,6-Dimethyl-3,6-epoxyocta-7-enoic acid 27:594 2,6-Dimethyl-3-alkylpyrazines 5:227,237,238 2,5-Dimethyl-3-alkylpyrazines 5:227 2,5-Dimethyl-3-citronellylpyrazines 5:225,230,239,246,261 2,5-Dimethyl-3-ethylpyrazines 5:222,225,231-237,249-251 2,6-Dimethyl-3- ethylpyrazine s 5:223,237,238 2,5-Dimethyl-3-isobutylpyrazines 5:223,228,230-232,238 2,6-Dimethyl- 3-i sobutylp yrazine s 5:223,237,238 2,5-Dimethyl- 3- isopentyl- 6-( 1-hydroxyisopentyl)-pyrazine 5:226, 246,247,266 2,5-Dimethyl-3-isopentyl-6-(E-isopent1-enyl)-pyrazines 5:226,245 2,5-Dimethyl-3-isopentyl-6-(isopent-2enyl)-pyrazines 5:226,245,266 2,5-Dimethyl-3-isopentylpyrazines 5:223,224,227-233,237,238,240, 243,244,246,251,259-261
269 2,6-Dimethyl-3-isopentylpyrazines 5:224,227,237 2,5-Dimethyl-3-methylpyrazine s 5:222, 228,232-237 2,5-Dimethyl-3-n-alkylpyrazines 5:232-237 2,5-Dimethyl-3-n-butyl-pyrazines 5:224,232,237,238 2,6-Dimethyl-3-n-hexylpyrazine 5:225,237,238 2,5-Dimethyl-3-n-pentylpyrazines 5:225,228,232,259,260 2,6-Dimethyl-3-n-pentylpyrazines 5:225,237,238 2,5-Dimethyl-3-n-propylpyrazines 5:223,228,229,232, 233,240 2,6-Dimethyl-3-n-propylpyrazines 5:223,232,237 3,7-Dimethyl-3-phenyl-7-octene 8:10 cyclization of 8:10 2,5-Dimethyl-3-phenylethylpyrazine 5:257 2, 6-D ime th y l- 3 -s ec-butyl-p yrazines
5:223,237,238 2,5-Dimethyl-3-sec-butyl-pyrazines 5:223,238 (3S,4R)-3,7-Dimethyl-4-hydroxyo ct-6enoic acid 11:414 3,3-Dimethyl-4-pentenoic acid 22:203 2,3-Dimethyl-5-isobutylppyrazines 5:223,227,232 2,2-Dimethyl-5-nitromethylpyrrolidin- 1ol 12:284 (E)-3,7-D imethyl-5-oc tene-1,7-diol 25:138 (E)-2,6-Dimethyl-6-hydroxy-2,7octadienoic acid 25:140 3,7-Dimethyl-6-octene-l-al 25:132 3,7-Dimethyl-7-octene-l,6-diol 25:138 3,3-Dimethyl-8-nitro-4-oxyoctahydroindolizidine-5-ol 12:284,285 10,13-Dimethyl-9-tetradecen- 1-ol 26:66 hydrogenation of 26:66 10,13-Dimethyl-9-tetradecen-l-ol 26:66 Dimethylacetamide dimethylacetal 14:722-724 3,3-Dimethylallyl alcohol 7:100
3,3-Dimethylallyl bromide 8:70 Dimethylallyl diphosphate 7:323,324,330,348,352 Dimethylallyl pyrophosphate 22:255 4-(y,T-Dimethylallyl) tryptophan synthase 11:200 3-(1,1-Dimethylallyl) xanthyletin 4:374,375,399,400 synthesis of 4:374,375,399,400 1-(3,3-Dimethylallyl)-2hydroxynaphthalene 4:394 6-(3,3-Dimethylallyl)-7hydroxycoumarin 4:385,386 3 '-(T,T-dimethylallyl)-kievitone 28:228 biological activity of 28:228 8-(T,T-dimethylallyl)-wighteone 28:228 biological activity of 28:228 3-c~,c~-Dimethylallyl-4-hydroxy-6methoxy benzaldehyde 21:741 3,3-Dimethylallyldilaurylsulfonium perchlorate 8:40 Dimethylallylindole 2:447 Dimethylallylkaemp feride 26:802 8-y,y-Dimethylallylwighteone 25:541 Dimethylaluminium benzenethiolate 14:755 Dimethylaluminium complex 14:750 Dimethylaluminium tert-butyl sulphide 1:271,272 Dimethylaluminum amide 1:288 Dimethylamino pyridine 21:739 D4-(imethylamino) pyridine 12:328,473 2-Dimethylamino- 1,2-dihydroacronycine 20:800 2-Dimethylamino-5-methoxy-benzoquinone 13:434 (9R)-Dimethylamino-9-deoxyerythromycin A 13:181 Dimethylaminocinnamaldehyde 21:542, 546,550 Dimethylaminocinnanaldehyde assay 21:511,521 4-Dimethylaminopyridine (DMAP) 11:154;24:24,25 a-Dimethylation 6:8 in (+)-brasilenol synthesis 6:8 7-12-Dimethylben[a] anthracene (DMBA) 10:4;25:937;20:508;25:44
270 Dimethylbenz[a]anthracene 21:7,12,705 7,12-Dimethylbenzanthracene (DMBA) 21:744;30:762 effect on skin papillomas 30:762 4,5-Dimethylbenzo [b] furan 5:277,278 7,12-Dimethylbenzyl [a] anthracene (DMBA) 24:217 N,N-Dimethylbenzylamine 5:827,828 endo-7,7-Dimethylbicyclo-[3.3.1 ]nonane-3-ol-9-one 15:135 Dimethylchlorosulfonium chloride 9:526 4,4-Dimethylcholestane 25:56 4,4,-Dimethylcholestane-3 a,5 a-diol 25:56 2,2-Dimethylchromans 13:367 Dimethylcopper lithium 1:263 Dimethylcrocetin 26:303 4,4-Dimethylcyclopentene 13:36 4,4-Dimethylcyclopentenone 13:9,14 5,9-D imethyl-dec a-2,4,8-trienoate 20:839 2,5-Dimethyl-E- styryl-pyrazines 5:225 3,7-Dimethylet- 6- ene- 1,2,3 ,-triol 25:134 N,N-Dimethylethanolamine 5:229 Dimethylformamide 21:597 Dimethylformylpyrazine 5:240,241 2,5-Dimethylfuran 27:850 (+)-Dimethylisoariciesinol-2-a-xylose 26:195 ot,cx-Dimethylisobutyric acid 21:224 (3R,4S)-N, O-Dimethylisostatine 12:477 3,7-Dimethyl-l,6-octadien-3-ol 25:140 3,7-Dimethyl-l-octene-3,8-diol 25:138 (-)-Dimethylmatairesinol 18:558 (3Z)-4,8-Dimethylnon-3-en- 1-yl sodium sulfate 28:721 as sulfated alkene 28:721 N, O-Dimethylnorbelladine 20:359 from Pancratium maritimum 20:359 ( 1'E, 5'E)-2-(2', 6'-Dimethylocta- 1', 5', 7'trienyl)-4-furoic acid 29:91 activity in PLA assay system 29:91 ( 1'E, 5'Z)-2-(2', 6'-Dimethylocta- 1', 5',7'trienyl)-4-furoic acid 29:91
activity in PLA assay system 29:91 2E-6E-2,6-D imethylocta-2,6,-diene-1,8diol 25:138 2E-6Z- 2,6-D imethylo cta-2,6,-die ne-1,8diol 25:138 7,11-Dimethyloleoside 26:334,343 4,4-Dimethyloxazolidin-2-thione derivative 12:164,166 (2R,3R)/(2S,3S)-2,3-Dimethylpentane1,2-diol-enantiomeric pair 15:86 Dimethylphenylethylpyrazine 5:241 ( 1S,R)- 1-Dimethylphosphinyl-2,3- Oisopropylidene-D-glycerols 6:353,355 3- ~-cx-Dimethylpropyl-4,6dimethoxybenzoic acid 21:741 2,5-Dimethylpyrazines 5:222,228,233, 237 2,6-Dimethylpyridine 6:424-426 5,5-Dimethyl-pyrroline-N-oxide 22:316 Dimethylsodium 4:322,323 4,4,-Dimethylsterols 25:56 (+)-(R)-3,3-Dimethylsulfonio-2methoxy-pyropanoate 25:846 5-Dimethylsulfonio-2-methoxypropanoate 25:846 3-Dimethylsulfoniumpropionate(DMSP) 25:846 Dimethylsulfoxonum methylide 6:550, 551 Dimethylsulphoxide 21:597;27:512 CH3SOCH2 from 27:512 10,13-Dimethyltetradecanoic acid 26:65-67 total synthesis of 26:67 9,13-Dimethyltetradecanoic acid 26:65,66 total synthesis of 26:66 2,2'-N, N-D imethyltetrandinium dichloride (bisbenzylisoquinoline) 29:578 effects on ACE 29:578 3-(4,5-Dimethylthiazol-2-yl)-2,5diphenyltetrazolium bromide method (MTT) method 25:266 Dimethyltryptamine 2:395 N,N-Dimethyltryptamine 21:68,84 1,3-Dimethyluric acid 22:6
271 1,7-Dimethylxanthine 22:5,6 2,5- Dime thyl-Z- 3- styryl-p yrazine s 5:225,239-241,257,262 Dimethyl-j%propiothein 25:846 2,6-Dimethyoxy-l,4-benzoquinone 23:537 5,8-Dimethyoxyisocoumarin 7:227,228 from Artemisia carvifolia 7:206 from soyasaponin I 7:227,228 3,5'-di-O-methyl-myricetin 7:227 3',4'-Dimetoxyflavone 5:653 Diminazene (berenil) 26:786 Dimnoline B 25:818 Dimoracin 20:282 Dimorphecolic acid 1:533,534 synthesis of 1:533,534 Dimsyl sodium 6:482,492,493 Di-myristoylphosphatidylcholine (DMPC) 18:839 2,4-Dinitro-phenylhydrazone 8:43,319 bis-Dinitrophenylhydrazone derivative 15:228 of myoporone 15:228 Dinklageine 15:228 from Strychnos dinklagei 6:522 spectral data of 15:228 synthesis of 6:526 Dinocophylline B&C 26:822,823 Dinoflagellates 17:20;21:300,301; 23:178,185;27:875;30:521 Dinophyceae 6:134,135 Dinophysis 21:301;27:875 Dinophysis acuminata 5:384 Dinophysis fortii 17:20;25:729 Dinophysistoxin-1 17:19,269 Dinophysistoxin-2 17:20 Dinophysistoxin-3 17:19 Dinoponera grandis 5:223,224,229,254 Dinorcholenic acid 16:323 Dinor-sesquiterpenes 9:65 26,27-Dinortyphasterol 16:352 Dinosterol 9:47;23:169 Dinoxanthin 23:179 1,6-Di-O-3-Nitropropanoyl-13-Dglucopyransoide 27:522 3,4-Di- O-acetyl- 1,2:5,6-di- Ocyclohexylidene-myoinositol 18:426
2,3-Di-O-acetyl- 1,6-anhydro-3-Otrifluoromethylsulfonyl- f3-Dgalactopyranoside 8:331,341 Di-O-acetyl-2,3-dideoxy-[3-D-threo-hex2, 1-(4,6-enopyranosyl) uracil 4:236,237 synthesis of 4:236,237 4,6-Di-O-acetyl-3-deoxy-D-glucal 14:146 3,4-Di- O-acetyl-6- O-trityl- 1,2cyanoethylidene-a-D-galactose 14:241 3,4-Di- O-acetyl-6- O-trityl- 1,2-Ocyanoethylidene-13-D-manno se 14:240,246 (+)-2',4'-Di-O-acetyl-7,8-dihydronogarene 14:67,68
(+)-2',4'-Di-O-acetyl-7,9-di-epi-7-con-
O-methylnogarol 14:75 (+)-2',4'-Di-O-acetyl-7-con-Omethylnogarol 14:75 (+)-2',4'-Di-O-acetyl-7-methoxynogarene 14:80 (+)-2',4'Di-O-acetyl-9-benzyloxy-9demethyl-9-methoxynogarene 14:82(+)-2',4'-Di-O-acetyl-9-demethyl-7,9dimethoxy-nogarene 14:82 (+)-2',4'-Di-O-acetyl-9-demethyl-7methoxynogarene 14:80 (-)-2',4'-Di-O-acetyl-9-demethyl-9hydroxy-7-methoxynogarene 14:82
(+)-2',4'-Di-O-acetyl-9-epi-7-
deoxynogarol 14:71 2',4'-Di-O-acetyl-con-nogarol 14:74 3,6-Di-O-acyl-4-deoxy-[3-D-glycerohex-3-enopyranosyl-2-ulose 10:353 3,4-Di-O-benzoyl-2-O-trityl-a-Lrhamnopyranoside 14:242 6,7-Di-O-benzoylcastonospermine hydrochloride 12:345 1,4-Di-O-benzoyl-myo-inositol 18:421 4,6- Di- O-b enzylide ne- 2,3- O-p arato luenesulfonyl-c~-D- glucopyranoside 14:154 4,6:4 ',6'-D i- O-benzylidene-~-c~'trehalose 14:149
272
1,6-Di-O-benzyl-N-acetyl-muramic acid methyl ester 6:388,389 1,3-Di-O-caffeoylquinic acid 25:920 3,4-Di-O-caffeoylquinic acid 25:920 3,5-Di-O-caffeoylquinic acid 25:920; 27:418 3,6-Di-O-caffeoylquinic acid (3,5DCQA) 25:938 4,5-Di-O-caffeoylquinic acid (AQAs) 25:920,938,939;27:418 Di-O-caffeoylquinic acids 25:921,947, 948 Dioclea glabra (Dioclea leiophylla) 29:598 1,2:3,4- Di- O-c yclohex ylidene-myoinositol 18:428 ent-3fl-6fl-Dihydroxy- 13-manoyl oxide 25:261 Di-O-hemiphthalates of olean- 12- ene-3 fl,30-diol (deoxyglycyrrhetol) 25:58 3:5,9:11-Di-O-isoproplidene derivative 6:264,265 Di-O-isopropylidene-cx-D-glucofuranose 1,2:5,6;6:282,283 1,2: 5-Di-O-isopropylidene-Dglucofuranose 14:159 Di-O-isopropylidene-(+)-valienamine 10:507 4,7: 5,6-Di- O-isopropylidene-( 1,4,6/5)4,5,6-trihydroxy- 3-hydro xymethyl- 2cyclohexenylamine 10:511,512 1,2:5,6-Di- O-is opropylidene- 3- O-ptoluenesulfonyl- D- glucofuranose 14:171 1,2:5,6-Di- O-isopropylidene-3- Otrifluoro-methyl-sulfonyl-cx-Dallofuranose 8:329 1,2:3,4-Di-O-isopropylidene-6-O-ptolylsulfonyl-cx-D-galactopyranose 8:339,340 1,2:5,6-D i- O-isopropylidene-Dglucofuranose 14:168 1,2:4,6-Di- O-is opropylidene-Dhexofuranose 14:160 from D-allose 14:160 from D-altrose 14:160 from D-galactose 14:160
from D-glucose 14:160 from D-gulose 14:160 from D-idose 14:160 from D-mannose 14:160 from D-talose 14:160 Di-O-isopropylideneglucofuranose 14:157 S-methyl dithiocarbonate 14:157 1,2:3,4-Di-O-isopropylidene-cx-Dgalactopyrano se 10:476 1,2:5,6-Di-O-isopropyli dene-cx-Dglucofuranose 14:152 2,3: 5,6-Di-O-isopropylidene-cx-Dmannofuranosidel0:541 2,3:4,5-Di-O-isopropylidene- f3-Dfructopyranose 12:350 (+)- 1-deoxy-6-8a-Di-epicastanospermine from 12:350 (-)- 1-deoxy-epi-castanospermine from 12:350 1,3-Diol monotosylate 3:73 vic-Diols 2:173 22,24-Di-O-methyl soya-sapogenol B 7:157,158 from soyasaponin I 7:157,158 3-O-Di-O-methyl xylose 7:298 2,4-Di- O-methyl- [3-D-quinovopyranosyl-( 1>>2)-5-O- sulphate-f3D-fucofuranosyl 15:66 from Dermasterias imbricata 15:66 ent-8,9-Di-sclareol 25:252 ent-8,9-Di-epi-sclareol 25:252 Dioncopeltine A 26:822,823 antiplasmodial activity of 26:822,823 Dioncopeltine B 26:822,823 antiplasmodial activity of 26:822,823 Dioncophyllaceae 20:407-409,417 Dioncophylline 20:265 Dioncophylline A and C 20:408, 418,437,438,440 DIOP 13:72 2,6-Di-O-penthyl-3-O-trifluoroacetyl 27:368 Dioscin 21:636
273
Dioscorea batatas 23:342 Dioscorea collettii var. Hypoglauca 21:636 Dioscoreajaponica 21:584 Dioscoreophyllum cumminsii 27:19 monellin from 27:19 Diosgenin 2:443,444;7:19;23:573,821 Diosma crenulata 29:579 Diosmetin 20:712;22:328;25:618; 26:746,756;27:844 from Salvia candidissima 20:712 Diosmetin (5,7, 3'-trihydroxy-4'methoxyflavone) 29:577 effects on aminopeptidase N 29:577 Diosmin (3', 5,7-trihydroxy-4'-methoxy7-O-rutoside) 29:579 effects on ACE 29:579 Diosmin 23:747;26:752,755-757,759, 766 Diospyrin 26:804 Diospyros 7:406,423 Diospyros abssinica 7:417 Diospyros canaiculata 2:224 Diospyros kaki Thunb 19:246;21:498; 29:588 Diospyros leucomelas 22:105,119,125 Diospyros montana (Ebeaceae) 2:231,754;26:804 Diospyros perigrina 29:578 Diospyros usmabarensis F. 7:427, 435;22:520 for epilepsy 22:520 Diospyros zombensis 7:417,427,429 2,9-Dioxabicyclo [3.3.1] nonane 14:108 2,7-Dioxabicylo [4,3.o] honane 25:803 Dioxacyclohexenone 1:642 Dioxanone 12:15,16 Dioxapyrrolomycin 25:757,794;26:488 1,6-Dioxaspiri[4,4]nonane 19:128 (R/S) 1,6-Dioxaspiro [4.5] decane 14:523,524 asymmetric synthesis of 14:523,524 (R/S) 1,7-Dioxaspiro [5.5]-undecane 14:521-526 asymmetric synthesis of 14:521526 from Dacus oleae 14:521
from (S)-malic acid 14:521,522 from (-)-menthyl (S)-p-toluene sulfinate 14:522,523 Dioxepane 10:218,219 synthesis of 10:218,219 Dioxepinooxindole ring system 28:360 construction of 28:360 Dioxin 26:756 antagonist effect of 26:756 2H,4H, 1,3-Dioxin derivative 12:160,161 1,3-Dioxo-7c~, 11[3H-2,3-secogermacra4Z,9Z-dien- 12,6cz-olide 27:573 Dioxoabieta-8,13-diene 20:670,11,12 3,5-Dioxoalkanoates 11:114 Dioxoaporphines 20:480 (Z)- 1,4-Dioxodec-7-ene 19:161 Dioxoester 11:117 1,1,-Dioxo-l,4-thiazine ring 25:861 1,3-Dioxolan-4-ones 1:603,609 1,3-Dioxolanes 1:584 Dioxolanes 1:644 Dioxopiperazenes 24:1034-1040,1080 10,17-Dioxosparteine skeleton 27:272 9~, 13c~-epi dioxyabiet-8( 14)-en- 18-oic acid 29:99 activity in EBV assay system 29:99 Dioxygenases 9:559 3,4-Dioxygenated flavones 30:240 3,2'-Dioxygenated flavonoids 5:673694 Dioxygenation 9:560,561,566,567, 570,573,575 R-Dioxygenation 9:574,575 Di-palmitoylphosphatidylcholine (DPPC) 18:839 5,5'-Dipentacene 14,14' (5H,5'H)-dione 11:126 Dipeptide 26:1224 Panek's synthesis of 26:1224 Dipetallolema viteae 26:487 Diphenol-oxygen oxide reductase 25:654 Diphenols 17:368 o-Diphenols 25:654,670 Diphenyl phosphane chloride 9:524 Diphenyl phosphorazidate (DPPA) 4:83
274
2,2-Diphenyl- 1-picrylhydrozyl (DPPH) 23:769 1,1-Diphenyl-2-picryl-hydrazyl (DPPH) 22:318;23:534;25:934,948 (S, S)- 1,2-Diphenylethane- 1,2-diol 11:423,424 1,7-Diphenylhept-4-en-3-one 23:803 Diphenylphosphoryl azide 10:289,290, 641,644,645,652,656,657 1,2-Diphenylpropane derivatives 27:894 Diphosgene 12:113 Diphospha adamantane 9:528 1,3-Diphospha-heterocycles 9:529 Diphyilin asioside 26:226 Diphylleia 26:172 Diphylleia cymosa 5:492 Diphyllin 5:461,462,493 ;26:226 Diphyllin acetate 26:194 Diphyllin acetyl apioside 26:263 Diphyllin apioside-5-acetatc 26:226 Diphyllin natural products 26:166 Diphyllinin 26:194 Diphyllinin crotonate 26:194 Diphyllinin monoacetate 26:194 Diphyllin-O-apioside 26:194 Diphyllin-O-apioside-5-acetate 26:194 Dipiperidine 21:107 Dipiperidine spiroalkaloids 14:748 biosynthesis of 14:748 hypothetical 14:748 Dipiperidine-[~-carbolines 14:759-765 Dipladenia martiana 29:578 Diplamine 10:244;25:820,821,893 Diplococcus ganera 29:311 Diplodia gossypina 25:162,166,168,170 Diplodia maydis 4:600 Diplodiatoxine 4:600-602 biomimetic synthesis of 4:620 synthesis of 4:600-602 Diplodiosis 4:600 Diplophyllin 2:278,279 Ent-Diplophyllolide 2:278,279 Diplophyllum albicans 2:278;24."183 Diploptera punctata 22:376,382 Diplorhoptrum 6:422,423 Diplosoma sp. 25:821 ;28:636 diplamine from 28:636
Diplosoma virens 23:244;25:888; 28:644,645
Dipodascus sp. 12:337
Dipolar [3+2]cycloaddition 19:155 1,3-Dipolar addition 1:230,231,291 1,3-Dipolar cycloaddition 1:227,278, 284,285,324-344 ;4:435 ;10:65,66, 138,139,215,216,11:238-41,264,283 [3+2]-Dipolar cycloaddition 13:191,500 Dipolar cycloaddition 13:84-86;19:42 intramolecular 13:84-86;19:42 of methyl acrylate 19:309 of alkenes 16:463 of nitrile oxide 16:464 to 3-oxidopyrazinium 10:135 Dipolar learsiae 25:788 Dipole LUMO control 1:363 Dipole moment 30:534 Diprenylated chalcones 29:773 antileishmanial activity of 29:774 Diprenylated flavanones 29:781 abyssinone III as 29:781 6,8-diprenyleriodictyol as 29:781 dorsmanine E as 29:781 dorspoinsettifolin as 29:781 epidorsmanin F as 29:782 7,8-[2"-(1-hydroxy-1methylethyl)-dihydrofurano]-6prenyl-5,3 ',4 '-trihydrox yflavone as 29:782 linklagin A as 29:781 lonchocarpols C derivatives as 29:782 6,8-Diprenylflavanone 4:378,380 from 7-hydroxy-flavanone 4:378,380 in azetidinone synthesis 4:437 6,8-Diprenylnoreugenin 4:382,384 6,8-Diprenylorobol 28:243 anti-Helicobacter pylori activity of 28:243 Diprian pini 27:384 Dipropyl disulfide (DPDS) 23:469 Dipropyl sulfide (DPS) 23:459,469,476 N,N-Diprotected 4:124 L-alaninals 4:124 Gt-amino aldehydes 4:124
275
Dipsacus afer 21:672 D-(+)-DIPT 19:445,480,490 D-(-)-DIPT 19:490 DIPT 4:172-174,179,186,187 Dipterocarpaceae 23:531-561 bioactive constituents of 23:531561 genera in 23:532 Dipterocarpaceae sp. 27:766 Dipterocarpus alatus 23:532 Dipteryx alata 29:598 Dipyranoside 21:432 Dipyrone 30:192 as analgesic/antipyretic 30:192 Dipyrromethane 9:592,593 Diquat 26:374 Diquinane 13:3-52 diterpenes 13:3-52 sesquiterpenes 13:3-52 sesterterpenes 13:3-52 synthesis of 13:3-52 Diradical trapping 3:20 Dirca occidentalis 26:219 genkwanin from 26:219 (+)-lariciresinol from 26:219 sitoindoside II from 26:219 Direct cis-hydroxylation 14:183 Direct-acting mutagen 30:174 daunorubicin as 30:174 methyl methanesulfonate as 30:174 Directed hydromagnesiation 10:29,30 Directed-aldol condensation 15:15 Dirhodium tetrakis (trifluoroacetate) 10:210 Diribonucleoside 2',3'-cyclic phosphates 14:285 Dirithromycin 13:171,172 Dirman 17:28 c~-l,4-Disacccharide 8:369,370 Disaccharide 6:377,29,33,50,53,60, 62,70;10:338;11:469 synthesis of 11:469 semi-synthesis of 17:636 Disaccharide acids 6:401,407,412,413 Disaccharide dipeptides 6:395,396, 398,406-409,41-416 anomeric characterisation of 6:413,416
anomeric deprotection of 6:413416 tert butyl ester of 6:413-415 2D COSY spectrum of 6:407,408 synthesis of 6:397,398,406,407 Disaccharide lactone 6:395,396,407 Disaccharide methyl ester 6:395,396 synthesis of 6:395,396 Disaccharide thioether 8:342 Disaccharide-L-alanyl-D-isoglutamine benzyl ester 6:410,411 C-Disaccharides 3:223,224 synthesis of 3:223,224 c~-Disaccharides 30:459 yield of 30:459 1,2-Disaccharides 8:362 synthesis of 8:362 Discadenine 9:220 Disc-diffusion method 20:712 Discobahamin A 23:341 Discobahamin B 23:341 Discobahamins A&B 26:1202 Discodermia 25:867;26:1175;28:138, 679 antifungal activity of 28:139 cytotoxic activity of 28:139,679 deepwater species of 28:679 polydiscamide A from 28:679 Discodermia calyx 5:396;25:731; 26:1204;27:877;28:713 Discodermia dissoluta 21:411 ;26:1205 discodermide from 21:411 Discodermia kiiensis 26:1201,1204 Discodermia polydiscus 25:763 Discodermia sp. 21:252;26:1201,1202 calyculins E,F from 21:252 Discodermide 26:1206 Discodermin-halicylindramide 25:864 Discodermins A-D 26:1201,1202 Discodermins E-H 26:1201,3202 Discodermis A-H 25:665,865 Discodermolide 26:1205,1206,1243, 1245-1248;30:3,4,5,6,10-12, 13-19,17,19-21,22-26 against human lung carcinoma cell 30:5 as antitumor agent 30:3 as immunosuppressive agent
276
30:3 as microtubule stabilizing agent 30:5 biological activity of 30:4 crystal X-ray crystallography of 30:4 inhibition of host-splenomegaly response 30:4 1D/2D NMR spectra of 30:4 isolation of 30:4 Marshall's synthesis of 30:19-22 Myles' s synthesis of 30:10-12 olefinic linkages of 30:13 Paterson's synthesis of 30:22-26 Schreiber's synthesis of 30:6-10 reverse-phase chromatography of 30:4 silica gel chromatography of 30:4 Smith's synthesis of 30:13-19 suppression of two-way mixedlymphocyte reaction 30:4 structure elucidation of 30:4 structure of 30:3 synthetic routes of 30:3 total synthesis of 30:5,13 Discokiolide A-C 26:1203 Discorhabdin 25:824 Discorhabdin A 25:760,761,822 Discorhabdin alkaloids 25:708 Discorhabdin B 21:311 ;25:760, 761,822,823 Discorhabdin C 25:760,776 Discorhabdin D 25:822,823 Discorhabdin P 25:760,761 Discorhabdin Q 25:760,761,822,823 Discorhabdins 21:311 ;25:823 Discorhaines 25:707 Discovery 30:799 of natural opioid peptides 30:799 Discriminative functionalization 10:415 in hexopyranoses 10:415 of geminal dimethyl groups 10:415 Diseases 30:70 arteriosclerosis 30:70 asthma 30:70 atopic dermatitis 30:70 hyperlipidemia 30:70
Disiamyl borane (bis(3-methyl-2-butyl) borane 14:183 Disiamylborane 4:116,117 Dismosin 25:469 Disodium salt of phosphocombretastatin A-4 24:406 angiogenesis inhibitory activity of 24:406 anti-tumor vascular inhibition of 24:406 7-Dis-O-methylnogarol 14:78 (+)-Disparlure 16:695-696;19:481 synthesis of 16:695-696 Dispermol 23:682 Dispermone 23:682 Dispermoquinone 23:709;30:672 ~H NMR spectrum of 30:672 molecular formula of 30:672 structure of 30:673 Dispsacus saponin C 30:204 antinociceptive effects of 30:204 Dispuupehedione 25:715 Dissymmetrization 19:45 enzymatic 19:45 of meso compound 19:45 Distamycin 5:551,552 Distamycin analogues 5:558-564,567 synthesis of 5:558-564,567 Distamycins (pyrrole amidines) 24:546 antiviral microbial-derived compound 24:546 Distemonanthus benthamianus 5:676681 Distichol 23:533,535;26:1562 Distillation solvent extraction 21:575 Distolasteria nipon 7:299;15:55 Distortionless enhancement by polarization transfer (DEPT) 30:587 of (-)-hemone 30:587 Distratamide A 25:881,882 Distratamide B 25:881,882 Distratamide C 25:881,882 Distratamide D 25:881,882 Distyophaeria sericea 25:722 Distyostelium 25:526 Distyota ciliolata 25:722 1,3-Disubsituted tetrahydro fl-carboline 25:16,17
277 c&, 2,5-Disubstituted 2,5dihydrothiophene- 1,1-dioxides 21:387 ~,c~'-Disubstituted 3-piperidinol alkaloids 29:420 absolute stereochemistry of 29:421 trans-selectivity of 29:423 stereochemical control of 29:422 stereoselectivity of 29:422 N,N-Disubstituted amides 4:389 2,5-Disubstituted ant pyrrolidines 6:441,442 synthesis of 6:441,442 Di-substituted azulenes 14:336-338 oxidation of 14:336-338 N,N-Disubstituted benzyl amines 4:389 in metallation reactions 4:389 cis-Disubstituted butyrolactones 24:751,753 by Stobbe condensation 24:751 2,5-Disubstituted decahydroquinoline 19:3-13 3,5-Disubstituted indolizidines 11:245 absolute configuration of 11:245 from dendrobatid flogs 11:245 synthesis of 11:245-259 5,8-Disubstituted indolizidines 11:260267 via hetero Diels-Alder approach 11:260-267 synthesis of 11:260-267 3,5-Disubstituted indolizidines 19:24-37 ;27:236,240 conformers of 27:237 FTIR spectral analyses of 27:241 3-hexyl-5-methylindolizidines 27:241 (-)-myrmicarin 237A as 27:240 (+)-myrmicarin 237B as 27:240 structure identification of 27:240 synthesis of 19:24-37 5,8-Disubstituted indolizidines 19:3851;27:235,238 conformers of 27:237 mass fragmentation pathway of 27:238 synthesis of 19:38-51 cis-2,8-Disubstituted oxocane 10:232
2,8-Disubstituted oxocene 10:223 synthesis of 10:223 cis-2,5-Disubstituted piperidine 19:36 cis-ct, cx'-Disubstituted piperidines 14:571-574 synthesis of 14:571-574 2,6-Disubstituted piperidines 6:430,431 cis-~, ~'-Disubstituted pyrolidine 14:571-574 synthesis of 14:571-574 cis-2,5-Disubstituted pyrrolidine 11:241,242 by ozonolysis 11:241,242 (+)-monomorine I from 11:241,242 2,3-Disubstituted quinolines 3:393,394,396 synthesis of 3:393,394,396 2,4-Disubstituted quinolines 3:394,396 synthesis of 3:394,396 1,4-Disubstituted quinolizidine 27:235,238,244 mass fragmentation pathway of 27:238 NMR characterization of 27:244 qulnolizidine 217A 27:244 quinolizidine 231A 27:245 quinolizidine 233A 27:245 quinolizidine 207I 27:245 quinolizidine 235E 27:245 quinolizidine 275A 27:246 3,5-Disubstituted-2-formylpyrrolidine 19:316 4,5-Disubstituted-2-oxazo lidinone 12:427,428 from 4-methoxy-2-oxazolidinone 12:427 N,N'-Disuccinimidylcarbonate 21:165 Disulfide bond 2:28,30 Disulfide-containing peptides 2:36 Diterpene 30:748 Diterpene acid 27:13,23 from pine tree 27:13 structure of 27:23 Diterpene alcohol 5:3,31-37 Diterpene derivatives 30:706 Diterpene dibenzoates 20:475 of Caesalpinia pulcherrima 20:475
278 Diterpene isothiocyanates 25:853 Diterpene lactone 30:739 structure of 30:739 Diterpene synthetase (cyclase) 7:109,110 Diterpenes 2:402,403,404;5:3,3137;6:110,7:102,121,122,187189;15:252-260;17:8,11-15,27,148; 18:756 ;21:234 ;22:379;23:488,682; 24:196-202,284,799;27:830 reduction of 27:830 synthesis of 24:197-202 Diterpenes, bioactive 29:169 carnosic acid as 29:169 miltirone as 29:169 pisiferic acid as 29:169 stereoselective synthesis of 29:169 triptolide as 29:169 synthesis of 29:169 Diterpenoid alkaloid 25:534 aconifine 25:534 ajacine 25:534 avadharidine 25:528 bikhaconitine 25:534 cassaidine 25:535 cassaine 25:535 condephine 25:528 delcoline 25:528 delcorine 25:528 delphinine 25:534 falaconitine 25:534 indaconitine 25:534 Jesaconitine 25:534 lappaconitine 25:534 mesaconitine 25:534 N-deacetyllappaconitine 25:534 pseudoconitine 25:534 raynodine 25:535 Diterpenoids 9:78,265,272,283,293, 295,297,298,639-642; 14:63964;15:111-185;20:660;23:799; 27:857;30:707 biological activity of 30:707 from 2E, 5E, l OE-geranylgeranyl pyrophosphate 30:707 Diterpenoids (Di) 29:98 2,6-Di-tert-butyl-4-methylphenol 9:579 Dithaiothreitol 4:101
1,3-Dithialane system 1:537 synthesis of 1:537 1,3-Dithiane 6:307-309,332,338 Dithiane-epoxide coupling 30:14 1,3-Dithianyl derivative 30:434 acylation of 30:434 2-(1,3-Dithianyl)-lithium 30:458 1,2-Dithietane 10:229 synthesis of 10:229 Dithiins dipsaci 26:437 Dithioacetal 11:357;30:439,458 transformation of 30:439 ylides gene from 30:458 Dithioacetal S,S-dioxides 6:307-349 Dithioacetal S-oxides 6:307-349 Dithiocarbonates 1:452-453;26:1091, 1092 antimicrobial activity of 26:1091,1092 1,4-Dithiocello-thiocellobioside 8:348,349 1,4-Dithiodisaccharide 8:348,349 Dithioerythritol (DTE) 2:20 Dithiofurodysinin disulfate 25:815 4,4'-Dithiomaltotrioside 8:331 Dithiomethyl lissoclinotoxin C 25:833 Dithiothreitol 2:20,579;25:836 1,4-Dithio-D-cellobiose 8:347,349 Di-trans-polycis-ct-saturated prenols (dolichols) 8:66 Di-trans-polyscis-prenols 8:66 Dittrichia viscosa 22:428;25:613 quercetin from 22:428 3-O-methylquercetin from 22:428 7-O-methylaromadendrine from 22:428 Ditylenchus destructor 26:460 Ditylenchus dipsaci 26:493 Diuranthera major 21:675 diuranthoside B from 21:675 Diuretic 23:499 Bacopa monnira as 23:499 Diuretic activity 12:398;17:451;28:200 of genus Morus 28:200 Diuretic agent 23:642 of Teucrium sp. 23:642 (-)-3,4- Divanillyltetrahydrofuran 26:191
279 Divarine 26:1056 Diveprisine 2:125 Divergent synthesis 12:330 Diversifolin 29:89 activity in NFkB assay system 29:89 Diversifolin methyl ether 29:89 activity in NFkB assay system 29:89 Diversity-oriented synthesis 29:452, 463 ofaminocarbafuranoses 29:463 of carbafuranoses 29:452 Divinyl cyclopropane rearrangement 12:246,247 cis- 1,2-Divinylcyclobutanols 11:45,47 D ivinylc yc loprop ane-c y c loheptadiene conversion 3:287 Divinylketone 8:412 Diydronaphthalene 8:402,403 synthesis of 8:402,403 L-Djenkolic acid 26:481 Di dopamine receptor 25:529 DL-3-( 3,4-Dihydroxyphenyl) alanine 6:312 synthesis of 6:312 DL-Dopa (DL-3-(3,4-dihydroxyphenyl) alanine) 6:312 synthesis of 6:312 DL-epiisopodophyllotoxin 18:600 DL-myo-inositol 1,3,4,5tetrakisphosphate 18:413 D-lyxo-hexulosonic acid 30:419 DMACA assay 21:511,522,524,525 DMACA protocols 21:522,523 DMACA reagent 21:522,523 D-manno epimer 30:433 oxalacetic acid 30:433 D-mannono-nitriles 10:463 catalytic hemihydrogenation of 10:463 Nefreaction of 10:464 D-manno-octulosonic acid (KDO) 30:434 stereoselective synthesis of 30:434 D-mannosamine 30:452 D-mannose 30:433 reaction of 30:433
DMAP (4-dimethylaminopyridine) 11:154,157;21:739 DMAPP 7:98,110,11:201,202,19:520 DMAT synthase 11:202 DMBA 21:744;25:45,48,61,62,65 DMBA/TPA induced skin tumor 25:48 inhibition of 25:48 DMBA-TPA 21:642,643,645 DM-CCK sonication 18:844 DMDP (2,5-dihydroxymethyl-3,4dihydroxy-pyrrolidines) 7:13,14 DMSO 6:310,329,330 (Dmtl, Tic2)DYN-A-(1-11)-NH2 30:809 activity in functional bioassay 30:809 743-DNA 25:826 DNA 7:9 DNA complex 5:575-581 DNA polymerase 21:96;25:895 DNA polymerase activity 23:218 DNA polymerase B 25:871 DNA polymerase inhibitors 25:868 DNA synthesis 30:61,67 (R)-8-DNA synthesiser 19:539 DNA topoisomerase 21:96 DNA topoisomerase I inhibitors 28:621 ceramide 1-sulfates as 28:621 DNA viruses 30:395 DNA-damaging activity 20:467 DNA-damaging agents 20:460,20:461 DNA-damaging antitumor activity 25:796 DNA-damaging natural products 20:457-500 coumarin as 23:335,356,357, 393,550,553 18,19-dihydrousambarine as 26:1062 5', 6'-dihydrousambarensine as 26:1062 ecteinascidins as 23:253,255 flavopiridol as 21:135,136 magainin-2 as 27:807 strychnopentamine as 26:1062 strychnos bisindole as 26:1062 usambarensine as 26:1062 usambarine as 26:1062 vinblastine as 14:805 vincristine as 14:805
280
(Ac-D-Nal(2)-D-Phe(4CL)2-Pal(3)3-DCit6,D-Alal0) 27:795 DNA-methyl green assay 30:733 DNA-scission 30:164 by alkylresorcinol 30:164 DNA-virus 30:394 hepatitis B type of 30:394 D-NMR 21:584,1992 3-(2',3'-Doacetoxy-2'-methyl-butyryl) cauhtemone 7:141 Docosahexaenoic acid 28:565 in fish oils 28:565 y-Dodec-(6Z)-enolide 13:315 3Z,6Z,9Z-Dodeca-3,6,9-trienoic acid 21:306 Dodecahydro benz[f]indolo [2,3,-a] quinolizidine 25:20 Dodecanol 22:663 4-Dodecanolide 1:683,684 synthesis of 1:683,684 y-Dodecanolides 13:314 Dodecanoylphloroglucinol 5:753,754 Dodecapentaenedioic acid 21:408 Dodecatetraeneamide 21:385 6-Dodecynoic acid methyl ester 2:17 Dodonaea glabra 24:151,152 dodonosides A from 24:151,152 dodonosides B from 24:151,152 Dodonaea saponins 15:191;21:657 Dodonaea viscosa 7:139,427;25:276 Doebher-von Miller quinoline synthesis 1:171 Dolabelides A 19:557 Dolabella 25:724 Dolabella auricularia 4:87,420,421; 19:557,601 ;25:716,760,763,878, 887;28:648,649 sequence of 28:648 Dolabellane 25:690,790,791,888 Dolabrane akendo 1 29:100 activity in TPA bioassay system 29:100 [3-Dolabrin (tropolone monoterpene) 1:527;29:583 effects on carboxypeptidase A collagenase 29:583 synthesis of 1:527
Dolaisoleucine 12:477,483-486 synthesis of 12:477,483-486 Dolasta-1 (15),7,9-trien-14-ol 6:52 by intermolecular [2+ 1] cycloaddition 6:52 by intermolecular reductive coupling 6:52 by three-carbon annulation 6:52 from Dictyota divaricata 6:52 from Dictyota linearis 6:52 synthesis of 6:52 (+)-Dolasta-1 (15),8-dien-1413-ol 6:54 stereoselective synthesis of 6:54 Dolastane 6:52,54,79,182 Dolastatin 5:421 ;12:10,477,485,486; 12:10,477,485,486;5:421 ;25:10,716, 802,886,887 Dolastatin 10 28:145,649 antiproliferative activity of 28:145 as antineoplastic agent 28:649 Dolastatin 15 28:145 antiproliferative activity of 28:145 Dolastatin 3 28:648;4:87-89 as antineoplastic agent 28:648 synthesis of 4:87-89 Dolastatin F 25:887 Dolastatin I 25~87 Dolastatin-15 2/:806,804 Dolichodenis clarkii 5:224,253 Dolichol 22:253 Dolicholide 19:258 synthesis of 19:258 Dolichos biflorus 29:598 Dolichos kilimandscharicus 7:432,433 Dolichos lablab L. 19:247 Dolichos marginata ssp. erecta 7:413,414 Dolichyl [[3-33p] diphosphate 8" 107 Dolichyl phosphates 8:73,106 Domesticine 3:428 synthesis of 3:428 Domoic acid 1"/:21;21:70,302;26:479 DOPA 21:323;23:241 l-Dopa 21:587 Dopamine 18:53 ;21:10,18,50,57,68,84, 91,95,101,104 ;22:5,18,308,669,671,
281
673 ;24:55 ;25:516,530,535,536,538, 662 Dopamine D1 receptors 21:101;25:531 Dopamine D2 receptors 21:101;25:530, 532 type of G-protein-linked receptor 25:530 Dopamine receptors 21:95;22:22; 25:531 Dopamine signalling 25:531 Dopaminergic receptors 21:68 Dorestenia sp. 29:780 Dorimidazole A 17:18 Doris verrucosa 25:829;28:651 9-( 5-deoxy-5-methylthio- ~-Dxylo furanosyl)adenine from 28:651 digestive glands of 28:651 Dorstenia 29:793 Dorstenia barnimiana 29:795 Dorstenia barteri 29:777 Dorstenia brasiliensis 29:795 anticancer activities of 29:797 antileukodermic activities of 29:797 antimutagenic activities of 29:797 anti-tumor activities of 29:797 artemicide activities of 29:797 bacteriophagicide activities of 29:797 cytotoxic activities of 29:797 hepatoprotective activities of 29:797 radical-scavenging activities of 29:797 uses of 29:798 viricide activities of 29:797 Dorstenia bryioniaefolia 29:795 Dorstenia ciliata 29:772 Dorstenia contrajerva 29:763 Dorstenia dinklagei 29:787 Dorstenia drakena 29:763 Dorstenia elliptica 29:763 Dorstenia excentrica 29:763 Dorstenia gigas 29:763,767 Dorstenia kameruniana 29:783 Dorstenia lindeniana 29:763 Dorstenia mannii 29:781,782
Dorstenia poinsettifolia 29:795 Dorstenia proropens 29:774 Dorstenia psilurus 29:792 Dorstenia sp. 29:763 Dorstenia tayloriana 29:793 Dorstenia zenkeri 29:786 Dorylinae 6:421 Double cyclization reaction 10:121,122 Double dioxygenation 9:560,561 Double indolization 1:8,9 Double Michael addition 8:414,415 with extended acceptors 8:414, 415 with substituted ~,[3-unsaturated esters 8:412-414 with 2-trimethylsiloxycyclohexadienes 8:417 with c~,[3-unsaturated ketones 8:418 Double Michael reaction 3:143,144,735 Double-helical polynucleotides 23:120 Douglanin 7:232;27:551 Dounomycin 24:547 antiviral microbial-derived compound 24:547 Dowex 50(H § resin column 19:527 Dowex resin 22:285 Down-regulators (TNF-a) 25:465 PGE2 as 25:463 dexamethasone as 25:463 Doxorubicin 4:317-319;12:396,13:378, 379,14:3,21 ;21:136,157,174,177, 642;24:547 ;28:559,560,562;30:56 antiviral microbial-derived compound 24:547 as cancer chemotherapy drug 28:559;30:56 gastrointestinal toxicity by 28:562 immunotoxicity by 28:562 myelotoxicity by 28:562 Doxorubicin 14-O-~-D-galactoside 21:16t Doxorubicin 14-O-[~-D-glucuronide 21:161 Doxorubicin phosphate 21:160
282 Doxorubicin plus chitosan 28:560 tumor growth inhibition by 28:560 Doxorubicin-induced gastrointestinal toxicity 28:563 effects of chitosan 28:563 preventive effects of 28:563 12-Doxylstearate 30:170 mobility of 30:170 3-Doxysilychristin 26:255 as antihepatotoxic agent 26:255 DPDPE 30:817 analgesic activity of 30:817 DPY-4189 25:669 Dracaena loureiri 5:17;28:234 in apple juice 28:271 in cider 28:271 in pomace 28:271 nothofagin from 28:272 Dracaenones 5:19,20 APT spectrum of 5:19,20 biosynthesis of 5:20 ~3C-NMR spectrum of 5:20 CSCM 1D spectrum of 5:19,20 ~H-NMR spectrum of 5:17-20 INEPT spectrum of 5:19,20 synthesis spectrum of 5:20,21 Dracena mannii 21.'660 spiroconzole A from 21:660 Dracunculifosides 30:731 structure of 30:731 Dracunculin 7:225 Dragendorffs reagent 21:129,144 Dragmacidin 25:765 Dragmacidine D and E 25:798,799 Drechslera gigantea 6:555 Drechslera rostrata 26:227 Drechslera spp. 26:468 Dregamine 5:125 Dregaminol 5:125 Dregaminol methylether 5:127 Dreiding molecular models 30:196 Dreiding synthesis 6:45 DRH 30:448 synthesis of 30:448 D-ribo-2-heptulosonate 30:451 D-ribo-Deh ydrophytosphingosines 18:465 D-ribose 30:452
Driman-8,11-diol 1:663 synthesis of 1:663 Drimane 7:100,154,408;18:607;22:635, 636 Drimanic sesquiterpenes 6:108 Drimanolides 2:280 Drimartol A 7:224 Drimenin 4:407,408;20:469 (-)-Drimenin 6:14-15 Drimenin isomerisation 4:407,408 Drimenol 7:100,103,110,122,123 Drimenyl pyrophosphate 22:635,636 Drimys sp. 4:404 Drimys winteri Forst. 4:418 Drop method 22:493 Droplet counter current chromatography (DCCC) 24:137;25:205,206 Drosera capensis L. 26:115;830:345 cell suspensions of 30:345 Droserone 2:212-215,754,755 Drosophila 22:682;25:389;30:777 Drosophila melanogaster 18:698; 29:55;29:31 activity of alkaloids in 29:56 activity of ampelopsin B (distilbene) in 29:55 activity ofapiole in 29:56 activity ofbisphenol A in 29:56 activity of carnosiflosides in 29:55 activity of cis-resveratrol (monostilbene) in 29:55 activity of croweacin in 29:56 activity of cucurbitacins in 29:55 activity of deacetylpicracin in 29:55 activity of diethylphthalate in 29:56 activity of 2,3-dihydro-3[3methoxyichromolide in 29:55 activity of 2,3-dihydro-313methoxywithacnistine in 29:55 activity of 2,3-dihydro-3[3methoxy withaferin A in 29:55 activity of 23,24-dihydrocucurbitacin F in 29:55 activity of 2,6-dimethoxy-3,4methyl-enedioxy- 1-(2-
283
propenyl)-benzene in 29:56 activity of ecdysteroiods in 29:55 activity of 24-hydroxycarthamo sterone in 29:55 activity of industrial compounds in 29:56 activity of isoasarone in 29:56 activity of 3-epi-isocucurbitacin D in 29:55 activity of isomitraphylline in 29:56 activity of isopteropodine in 29:56 activity of kobophenol B (tetrastilbene) in 29:56 activity oflimonoids in 29:55 activity of lindane in 29:56 activity of marginatine in 29:56 activity of cis-nflyabenols (tristilbene) in 29:55 activity of phenylalkanoids in 29:56 activity of pipermargine in 29:56 activity of prieurianin in 29:55 activity of rohitukin in 29:55 activity of stilbenoids in 29:55 activity of suffruticosols (tristilbene) in 29:55 activity of ~-viniferin tristilbene in 29:55 activity of withanolides in 29:55 Drosophila melanogaster BI~ bioassay 29:55 alkaloids activity in 29:56 ampelopsin B (distilbene) activity in 29:55 apiole activity in 29:56 bisphenol A activity in 29:56 carnosiflosides activity in 29:55 cis-resveratrol (monostilbene) activity in 29:55 croweacin activity in 29:56 cucurbitacins activity in 29:55 deacetylpicracin activity in 29:55 diethylphthalate activity in 29:56 2,3-dihydro-3[3-methoxyichromolide activity in 29:55
2,3-dihydro-3 [5-methoxywithacnistine activity in 29:55 2,3-dihydro-3 [3-methoxywithaferin A activity in 29:55 23,24-dihydrocucurbitacin F activity in 29:55 2,6-dimethoxy-3,4-methylenedioxy- 1-(2-propenyl)benzene activity in 29:56 ecdysteroiods activity in 29:55 24-hydroxycarthamosterone activity in 29:55 industrial bioactive compounds from 29:56 isoasarone activity in 29:56 3-epi-isocucurbitacin D activity in 29:55 isomitraphylline activity in 29:56 isopteropodine activity in 29:56 kobophenol B (tetrastilbene) activity in 29:56 limonoids activity in 29:55 lindane activity in 29:56 marginatine activity in 29:56 cis-miyabenols (tristilbene) activity in 29:55 phenylalkanoids activity in 29:56 pipermargine activity in 29:56 prieurianin activity in 29:55 rohitukin activity in 29:55 stilbenoids activity in 29:55 suffruticosols (tristilbene) activity in 29:55 c~-viniferin (tristilbene) activity in 29:55 withanolides activity in 29:55 Drosophila melanogaster imaginal disc cell lines 29:33 Drug delivery system 21:615 Drug-DNA complex 23:9 Drug-effiux pump 21:158 Drummondins A-F 22:656 Drupellafragum 25:792 Drymis winteri 30:206 anti-inflammatory properties of 30:207
284
antinociceptive properties of 30:206 Dryophanta divisa 29:589 Dryopteris filixmas 26:431 DSM-IV 30:384 DSP values 17:118 Ds-penaustroside A 28:599 from sea cucumber 28:599 Ds-penaustroside B 28:599 from sea cucumber 28:599 DSPs 21:301 DTAOH 30:810,811 antagonistic effect of 30:810 8 antagonist activity of 30:811 DTAOH+DEL II 30:810 activity in tail flick test 30:810 Dt-B 25:118 Dt-C 25:118 Dt-E 25:118 DTH response 30:768,769 after infection 30:768 mononuclear cell infiltration due to 30:769 swelling due to 30:769 DTOH 30:810,811 8-antagonist activity of 30:811 antagonistic effect of 30:810 physiochemical properties of 30:811 DTOH+DEL II 30:810 activity in fail flick test 30:810 DTX-1,2,3 and 4 21:301 Duasmodactyla kurilensis 7:279,91,153 Dubamine 3:392,393 synthesis of 3:392,393 Dubinine 22:522,539 Dubioside F 15:211 Duboisia 17:395 Duboisia leichhardtii 22:742 Duboisia myoporoides 22:742 Duckweed (Lemna minor) 9:383, 384,386,387,389,390 Ducrosia anethifolia 23:341 Duct cell carcinoma of breast 1:276 Dufour glands 6:421,422, 453,454,457,458 Duguetia panamensis 9:402
Duhram 29:466 pyranoid carbasugars synthesis by 29:466 Dulcioic acid 21:690 Dulcitol 5:779 Dulucoside A 15:16;27:13,22;29:101 activity in TPA bioassay system 29:101 structure of 27:23 Dumasia truncata 25:106 Dunalia australis 20:191,194 Dunawithanine A,B 20:191 from Dunalis australis 20:191 Duocarmycin A 10:248 Duocarmycin C1 29:339 against Gram-positive bacteria 29:339 against Staphylococcus aureus 29:339 as anticancer antibiotics 29:339 in lymphocyte leukemia 29:339 in sarcoma 29:339 Duocarmycin C1 29:339 structure of 29:339 2cz,3[3-Dyhdroxy-olean- 12-ene-22,29lactone 648 13C-NMR data of 30:648 1H-NMR spectrum of 30:648 2D-NMR experiments of 30:649 HMBC spectrum of 30:649 structure of 30:649 DYN A analogues 30:818 DYN-A-(1-11)-NH2 30:809 activity in functional bioassay 30:809 (tic2)DYN-A-(1-11)-NH2 30:809 activity in functional bioassay 30:809 analytical properties of 30:809 (tic2)DYN-A-(1-13-)-NH2 30:809 activity in functional bioassay 30:809 analytical properties of 30:809 Dynorphin A 27:803 Dynorphins 22:24;27:801 ;30:806,193 as endogenous peptide opioids 30:193 biological activity of 27:801 effects of TIC insertion 30:806
285
Dysamide K 25:801 Dysamides 25:801 Dysazecine 6:487 from Dysoxylum lenticellare 6:487 synthesis of 6:487,488 Dysdercus chaluensis 22:387 Dysdercus cingulatus 22:387 Dysdercusfluvoniger 22:387 Dysdercus intermedius 22:387 Dysdercus supersetitisus 22:387 Dysidea 17:10,11;28:676 Dysidea arenaria 25:714 Dysidea avara 5:433,438;21:252; 25:693,814,815;28:668 Dysidea fragilis 6:69;28:702 nakafuran-9 from 6:69 (+)-upial from 6:65 Dysidea herbacea 4:404;21:283,284, 310,365;25:691,692,697,776,801, 815 ;26:463 ;28:142,665,666 dysideathiazole from 28:665 13-demethylisodysidenin from 28:666 13-demethyldysidenin from 28:666 isodysidenir from 28:665 immunosuppressant activity of 28:142 molluscidal activity of 28:142 9-monodechloro- 13-demethylisodysidenin from 28:666 11-monodechloro- 13-demethylisodysidenin from 28:666 polychlorinated peptides from 28:665 (22R,23 R)-22,23-methylene cholesterol from 9:37 Dysidea sp. 21:301 ;25:264,692,693, 698,815,869,896;28:666 15-acetylthioxyfurodysinin lactone from 28:667 [3-adrenoreceptor agonist from 28:668 barbaleucamide A from 28:668 benzothiazole S 1319 from 28:668 dysideaproline A from 28:668 dysideaproline B from 28:668
dysideaproline C from 28:668 dysideaproline D from 28:668 dysideaproline E from 28:668 dysideaproline F from 28:668 from Okinawa 28:668 proline-derived analogues of dysidenin from 28:668 (+)-Dysideapalaunic 6:20 aldose reductase inhibition of 6:20 from Dysidea species 6:20 synthesis of 6:21 Dysideathiazole 25:890 Dysideathiazole A 28:667 as polychlorinated amino acid derivative 28:667 X-ray analysis of 28:667 Dysideathiazole B 28:667 as polychlorinated amino acid derivative 28:667 X-ray analysis of 28:667 Dysideathiazole C 28:667 as polychlorinated amino acid derivative 28:667 X-ray analysis of 28:667 Dysideathiazole D 28:667 as polychlorinated amino acid derivative 28:667 X-ray analysis of 28:667 Dysideathiazole E 28:667 as polychlorinated amino acid derivative 28:667 X-ray analysis of 28:667 Dysideathiazole series 25:889 Dysidenin 25:889,890 Dysidia chlorea 25:801 Dysidin 28:142 antifeedant activity of 28:142 immunosuppressant activity of 28:142 molluscidal activity of 28:142 Dysinin 25:814 Dysmorphogenic 23:572 Dysodanthin A 26:212 cytotoxicity of 26:212 Dysodanthin B 26:212 cytotoxicity of 26:212 Dysosma 26:172 Dysoxylum 3:456;21:124,127
286
Dysoxylum binectariferum 21:134,147 Dysoxylum lenticellare 6:487 Dysoxylum malabaricum 21:134,152 Dyspepsia 5:754
Dytiscus marginalis 5:700 D-B cell proliferation 25:273 effect of prehispanolone on 25:273 D[3E blockers 27:283
E864-861 21:412 Earthworm 30:825,840 as antipyretic 30:825 as antitumor extract of 30:840 as diuretic 30:825 to treat clotting diseases 30:825 use in folk remedy 30:825 Earthworm fibrinolytic enzymes 30:826, 832,836,837,839,840,843 as fibrinolytic agent 30:839 as medicine 30:843 as plasmin-activator 30:839 biological function of 30:840 from Lumbricus rubellus 30:826 gene expression of 30:843 immunological results of 30:840 structure-based inhibitor modeling of 30:832 Earthworm plasminogen activator (e-PA) 30:826,843 Earthworm serine protease 30:830 Earthworm species 30:829 homologs from 30:829 site-mutation in 30:829 Earthworms 30:826 active components from 30:826 Earthworm-tissue plasminogen activator (e-TPA) 30:826,843 EBA-EA activation inhibition assay 25:58 Ebeinone 22:19 Ebelin lactone 23:503 Ebenifoline E-1 29:91 activity in TNFct assay system 29:91 Eburnamenine 13:94 Eburnamine 1:112,93,94
(+)-Ebumamine 14:636 synthesis of 14:636 Ebumamonine 5:187,189,190,632-636; 8:266;25:19 synthesis of 5:187,189,190, 632-636;8:266 (+)-Eburnamonine 14:728 from indoloquinolizidine enamine 14: 728 synthesis of 14:728 (-)-Eburnamonine 8:283;9:180;16:709710;19:143 from Vinca minor 8:283 synthesis of 16:709-710 Eburnan-type alkaloid 5:71,107-110 (-)-Eburunamenine 14:636 synthesis of 14:636 EBV 25:46 EBV assay system 25:45;29:87,88, 99,100 19-nor-Abieta-4(18),8,11,13tetraen-7-one activity in 29:100 abieta-8,11,13-trien-7-one activity in 29:99 abieta-8,11,13-triene-7(x, 15,18triol 7-acetate 29:99 cedrol activity in 29:87 10[3-hydroxycedrol activity in 29:87 12-hydroxycedrol activity in 29:87 methyl 8c~,14or, 12or,13otdiepoxy-abietan- 18-oate activity in 29:99 EBV bioassay systems 29:100 EBV genome 30:592 expression of 30:592 EBV inducer 30:592 n-butyrate as 30:592 EBV inhibitor 30:592 1,2,3,4-dehydrodeoxypo dophyllotoxin as 30:592 1,2,3,4-dehydropodophyllotoxin as 30:592 6,7-demethylenedeoxypodophyllotoxin as 30:592 bursehernin as 30:592 epimagnolin as 30:592
287
Hernandia ovigera as 30:592 podorhizol as 30:592 EBV-EA activation 21:642,643,645; 25:59 induced by TPA 25:59 EBV-EV activation 30:695 effect of Tripterygium wilfordii 30:695 inhibition of 30:695 Ecballium EETI-II 29:615 Ecballium elaterium 20:13 ;29:615 Ecdysone 2:169;25:515 ot-/[3-Ecdysone 20:248 c~-Ecdysone 26:700 Ecdysone synthesis 25:242 Ecdysteroid agonists 29:22 8-O-acetylharpagide as 29:24 against diphtera 29:22 against lepidoptera 29:22 as elicitors 29:23 as insecticides 29:22 bisacylhydrazines as 29:22 disadvantages of 29:22 3,5-di-tert-4-hydroxy-Nisobutylbenzamide as 29:24 from Ajuga reptans 29:24 in gene switch systems 29:23 maocrystal as 29:23,24 nonsteroidal 29:22 4-phenylamino- 1,2,3,4tetrahydroquinolines as 29:24 QSAR studies of 29:22 RG-102240 (GS-E) as 29:23 RH-0345 (halofenozide) as 29:23 RH-2485 (methoxyfenozide) as 29:23 RH-5992 (tebufenozide) as 29:23 2 [3,313,20R,22R-tetrahydro xy-25fluoro-5 [3-cholest-8,14-dien-6one as 29:18,19 Ecdysteroid antagonists 26:555 Ecdysteroid antagonists ampelopsin B 29:54 activity in BH bioassay 29:52 applications of 29:56 as pest control agents 29:56
biomedical applications of 29:59 bisphenol A as 29:54 classes of 29:52 cucurbitacins as 29:53 diethylphthalate as 29:54 2,3-dihydro- 3 [3-hydro x y withacnistine as 29:54 environmental protection by 29:59 from Hemsleya carnosiflora 29:53 from Iberis umbellata 29:53 24-hydroxycarthamosterone as 29:54 lindane as 29:54 pipermargine as 29:54 preurianin as 29:54 cis-resveratrol as 29:54 rohitukin as 29:54 use in crop species 29:57 use in gene switching technology 29:59 c~-viniferin as 29:54 Ecdysteroid phosphates 19:641 Ecdysteroids 19:631;26:699,700;29:3 accumulation in spinach 29:8 affinity labelling of 29:20 allelochemical properties of 29:8 analogues of 29:21 as chemical defence 29:8 biosynthesis of 19:629-634 chemistry of 29:17 3-dehydroecdysone as 29:7 25-deoxyecdysone as 29:7 detection in invertebrates 29:4 dimeric type of 29:21 docking studies of 29:49 effects in Homosapiens 29:9 effects on bile acid production 29:9 effects on cellular proliferation 29:9 effects on differentiation 29:9 effects on insect growth 29:7 effects on mammalian cells 29:39 effects on physical performance 29:9 effects on vertebrates 29:60
288 for gene-switching systems 29:21 from Ajuga decumbens 29:60 fluorescently-tagged 29:20 hormonal roles of 29:61 4a-hydroxy-7en-6-one chromophore of 29:4 20-hydroxyecdysone as 29:4 makisterones as 29:7 mode of action of 29:4 molecular modeling studies of 29:44,45 natural analogues of 29:18 non-natural analogues of 29:18,19 of arthropods 29:4 pharmacophore hypothesis for 29:46 polypodine B as 29:7 ponasterone A as 29:7 poststerone as 29:7 potency of 29:46 pterosterone as 29:7 QSAR of 29:4,43 receptors of 29:14 role in crop protection 29:17 role in metamorphosis 29:5 role in moulting 29:5 role in reproduction 29:5 rubrosterone as 29:7 taste receptors for 29:17 SAR of 29:3,16 structural diversity of 29:4,18 titres of 29:6 total synthesis of 29:17 turkesterone as 29:7 3-epi-Ecdysteroids 19:634 Ecdysterone 20:114;26:700 Ecgonine 22:7,722 (-)-Ecgonine 22:721 Echiguanine 15:458-461 Echiguanine A and B 15:459 Echimidine 26:874,876 Echinacea augustifolia DC. 22:393; 24:689;29:684 Echinacea sp. 29:683 Echinaster brasiliensis 15:55 Echinaster luzonicus 7:294 Echinaster sepositus 7:294,298;15:59
Echinasterosides BI,B2 7:298,300 Echinatin 28:228 biological activity of 28:228 Echinatine N-oxide 1:275 Echinocandin B 22:249 Echinocandins 22:62,248 Echinocaulone 22:634 Echinochloa crusgalli (L.) 27:217 Echinochloa frumentacea 24:57,60 Echinoclasterol sulfate 28:705 as antifungal substance 28:705 as cytotoxic steroid 28:705 from Echinoclathria subhispida 28:705 phenethylammonium salt 28:705 Echinoclathria sp. 25:814 Echinoclathria subhispida 28:705 Echinoclathrine B 25:814 Echinoclathrine C 25:814 Echinocystic acid 7:434;21:634,643; 25:60;30:747 structure of 30:747 Echinocystic acid glycoside 21:657 Echinocystis lobata 29:615 Echinocystis macrocarpa 7:330 Echinodermata 7:265,266 Echinoderms 7:265-316;21:314;28:716; 30:526 classes of 28:716 histidine derivatives from 28:716 living species of 28:716 metabolites of 28:716 Echinodictyum sp. 25:900;28:697 echinosulfonic acid A from 28:697 echinosulfonic acid B from 28:697 echinosulfonic acid C from 28:697 echinosulfone from 28:697 Echinoidea 7:43,103,104,265,282-285 Echinolactones A,B 7:136 from Echinophora lamellose 7:136 Echinolone 22:384,393,395 Echinophora lamellosa 7:136 echinolactones A,B from 7:136 glycyrrhetic acid from 7:136 smilagenin from 7" 136
289
Echinops echinatas 22:117,119 Echinoside A 7:269,271,280 Echinoside B 7:269,271,280 Echinosulfone A 25:900 Echinosulfonic acid A 25:900 Echinothuridae 7:283 Echitamidine 1:36 20-epi-Echitamidine 1:36 Echium piantagineum 19:247 Echium sp. 26:872 Echium vulgare 22:520 Echium wildpretti 26:874 Eciton hamatum 5:250 Ecklonia stolonifera 19:553 Ecklonialactone A 19:554 cytotoxic activity of 19:554 isolation of 19:553 relative stereochemistry of 19:553 Ecklonialactone B 19:553 Ecklonialactones 19:552 Ecological consequences 21:108 Ecology 21:364 of marine isocyanides 21:364 Economic viability 28:345 of 14[3-methyl- 14-c~-hydroxyMFA 28:345 of 15cx-methyl- 14et-hydroxyMFA 28:345 ECs 24:888-890 by magnosalin 24:888-890 Ecteinascidia turbinata 21:322;23:253; 25:707,825;28:640,641 antitumor activity of 28:640 ecteinascidins from 28:640,641 Ecteinascidins 10:248,249;21:321, 322,323,743 ;23:253,255 ;25:707,825 biogenesis of 23:253,255 Ectocarpene 21:305,306 Ectocarpus siliculosus 21:305,306 Ectoprotein CD38 25:535 Ectyoplasia ferox 26:66 ED-71 30:492 synthesis of 30:492 Edema 22:115;25:46 induced by 25:46 Edema inhibition (HPA) 25:46 by 12-O-hexadecanoyl- 16-
hydroxy phorbol- 13-acetate (HHPA) 25:45 Edema relief 23:362 by coumarin 23:335,353,356, 357,368,376,393,550,553 Edgar-Greene-Crabbe' intermediate 14:365 ' Edman degradation 2:33;9:489,499,549, 551 ;19:797;25:437 Edmonston A 21:665 EDTA 21:540;30:836 Edudiol 28:228 biological activity of 28:228 y-Eduesmol 21:583,584 Edulinic acid 23:674 Edulinine 22:536,542 (+)-Edunal 4:385,386 Eedeoma pulegioides L. 22:522 EFE 30:835,838,840-842 as plasminogen activator inhibitor 30:842 assays of 30:835 by photoreaction 30:841 fibrinolytic medicine from 30:842 in acute cerebral thrombosis 30:842 in acute diseases 30:842 in cerebrovascular thrombus 30:842 in peripheral limbs arteriovenous thrombus 30:842 in prevention of blood clotting 30:842 in radiation therapy 30:841 inhibition by fibrin 30:838 role in dissolution of thrombus 30:842 to treat AMI 30:842 use of antitumor drugs 30:840 EFEa 30:830,831 crystallization of 30:831 homology of 30:830 X-ray analyses 30:831 EFE-immobilized polyurethane surface 30:841 as antithrombogenic agent 30:841 effect on platelet activation
290
30:841 effect on platelet adhesion 30:841 Effective insect growth inhibitors 26:858 calopeptin as 26:858 dehydrodiisoeugenol as 26:858 galbacin as 26:858 galbegin as 26:858 licarin as 26:858 licarin B as 26:858 sesamin as 26:858 sesamolin as 26:858 veragensin as 26:858 Effector-receptor complexes 27:379 Effusanin A 15:173 from Rabdosia nervosa 15:173 Effusanin B 15:173 from Rabdosia langituba 15:173 from Rabdosia ternifolia 15:175 Effusanin E 15:173 from Rabdosia nervosa 15:173 from Rabdosia ternifolia 15:175 Eflornithine 26:787,792 EGb 28:185 activity against MPTP 28:184 effects on neuroendocrine system 28:185 effects on phospholipid metabolism 28:185 protective activity of 28:184 EGF receptor kinase 25:797,870 Egg white lysozyme 2:31,32,34,36 Egregia menziessi 19:554 EGTA 25:490 EGTA-Ca 2+ buffer system 25:490 EGTA-containing buffer 25:491,492 EGTA-treated plasma membrane 25:492 Ehrlich ascites carcinoma 25:939,957; 26:303 Ehrlich ascitis tumor cells 21:664 Ehrlich carcinoma 19:609;23:130 Ehrlich products 13:300 Ehrlich's reagent 9:592;19:755;26:1277 Ehuazulene 14:315 Eichhornia crassipes 26:359 (5Z,9Z)-5,9-Eicosadienoic acid 26:80
(11Z,15Z)-I 1,15-Eicosadienoic acid 26:89 (10Z, 15Z)-I 0,15-Eicosadienoic acid 26:90 total synthesis of 26:90 Eicosanoid 25:274,520,693,939 Eicosanoid production 25:615 Eicosanoid signalling 25:374 Eicosanoids 22:4 Eicosatetrainoic acid 22:126 9-Eicosene 26:361 Eicospentaenoic acid 19:552 biosynthesis of 19:552 4-Eicosphingenin 18:786 Eicosyl ferulate 26:666 elF4E-dependent mRNA translation 25:526 Eight-carbon sugars 4:172-175 by epoxide route 4:172-175 by osmylation 4:163-175 synthesis of 4:163-175 Eight-membered marine compounds 6:37 biosynthesis of 6:37 by cyclopropanone sliding reaction 6:37,210,218-220, 224-226,234 Eight-membered rings 3:77 by anionic oxy-Cope rearrangement 3:77 by [4+4] annulation 3:78 by dicarbonyl coupling 3:81 by Michael additions 3:83 by Nicholas reactions 3:83,84 by retroaldolization of enonenephotoadducts 3:74,75 by ring contractions 3:76,77 by transannular acylation 3:81, 82 from allylchromium-carbonyl coupling 3:81 synthesis of 3:73-111 Eilatian 25:532 Eilatin 10:247;23:276 Eimeria 26:804 Eimeria tenella 17:376 EIMS 30:584,587 of (-)-hernone 30:587 ofherveline A 30:583
291
Eiocosapentaenoic acid 28:565 in fish oils 28:565 Eisenia andrei 30:828 from Lumbricidae family 30:828 Eisenia fetida 30:826,828,829,832 EFE component A of 30:829 F-II homolog of 30:832 fibrinolytic activity of 30:826 from Lumbricidae family 30:828 isozymes of 30:826 Ekebergia senegalensis A. 2:117,118, 120,269;22:520 for epilepsy 22:520 Ekeberginine 2:117-120,95 Ekebergolactone A 2:269,270 Ekebergolactone B 2:269,270 long range dd correlation spectrum 2:269,270 NOE difference spectra 2:272 2D NOESY spectrum 2:272 Ekesenin 2:117 Elabunin 23:703 Elaeocanine 12:277;454 synthesis of 12:454 Elaeocarpus ganitrus 22:520 for epileptic fits 22:520 Elaeocarpus sphaericus 22:520 for epilepsy 22:520 Elaeocarpus tuberculantus 22:520 for epilepsy 22:520 Elaeocarpusin 4:718 thermolysis of 4:718 Elaeodendrol 7:152 from Elaeodendron glaucum 7:152 Elaeodendron buchananii 23:669 insect antifeedant sesquiterpenes from 23:669 Elaeodendron capense 23:655 Elaeodendron glaucum 5:152,757; 23:655 Elaeodendron schiveinfurthianum 23:655 (+)-Elaeokanine A 1:283,284,286,288, 289;12:189 asymmetric synthesis of 12:351, 352 from (+)-elaeokanine C 12:352 synthesis of 1:283,284,286,
288,289:12:189;13:487,488; 16:460 Elaeokanine B 1:284,286,289 synthesis of 1:284,286,289 (+)-Elaeokanine C 12:277,351,352 asymmetric synthesis of 12:277,351,352 (+)-elaeokanine A from 12:352 synthesis of 16:476 Elaeokanine C 12:289 from Elaeocarpus kaniensis 12:289 from 1-(methoxycarbonyl)-2methoxy pyrroline 12:292 synthesis of 1:277,278,282,284286;12:289-293 Elaeokanine E 12:277 Elaiophylin 16:713-714;26:453 synthesis of 16:713-714 ELAM-1 expression 30:70,71,291 baicalein effect on 30:291 induction by TRAP 30:70,71 Elaodendrum 18:741 Elasnin 5:590,591 Elastase 2:35; 30:832 characteristic of 30:832 of chymotrypsin 5:590 of human granulocyte 5:590 ofpancrea 5:590 of trypsin 5:590 Elastase inhibitor 5:590 from Streptomyces noboritoensis KM-2753 5:590 Elastatinal 30:836 Elatian 25:709 Elatosides 21:675 Eldana saccharina 11:414 eldanolide from 3:168;11:414 Eldanolide 11:414 from Eldana saccharina 11:414 from (R)-pinanediol methylboronate 11:414 synthesis of 11:414 (-)-Eldanolide 14:272,273;16:240,692 from levoglucosenone 14:272, 273 synthesis of 14:272,273;16:240, 692
292 (+)-Eldanolide 16:692 synthesis of 16:692 Electrically evoked contractions 30:801 Electrochemical detection 21:50 Electrochemical oxidation 14:325 of azulenes 14:325 of guaiazulene 14:325,326 Electrocyclic rearrangement 6:72 Electroenzymic reactions 20:877 Electrolysis 19:35 Electromicrobial dehydrogenation 20:867 Electromicrobial reductions 20:877 Electron chains 21:98 Electron mediators 20:821-824 n-Electron SCF-CI-DV MO method 17:39-40,45,47 Electron transfer 27:749 4,4'-bis-jatrorrhizine (v) 27:749 oxidative halogenation 27:750 oxygen transfer 27:751 N-dealkylation 27:754 O-dealkylation 27:754 Electron-demand 17:553 Electrophile-Responsive Element 26:951 Electrophiles 19:464;30:431 1,4-Electrophilic addition 1:487,488 Electrophoresis 19:648 Electrophoretic mobility 9:541 Electrophoretic patterns 5:838 Electrophoretic studies 5:836 Electrospray ionization 9:487,499,502 Electrospray Ionization Interface (ESI) 19:750 Electrospray ionization mass spectrometry 21:556 Eledoisin 27:800 Eleganediol 20:26 Elegansamine 15:484 from Gelsemium elegans 15:484 Elemane 7:168,216 by [2+2] cycloadditions 6:15 Elemanolide 7:216;23:160 from Artemisia hispanica 7:216 Elemanolides 24:72,91-98,103,104 [3-Elemene 21:276;23:545 Elemol 15:244;21:595
[3-Elemol 14:406-413 synthesis of 14:406-413 Elenoic acid 3:254,255 synthesis of 3:254,255 Elenolide 7:442,477,478 Eleocarpus 27:250 Eleocharis microcarpa 26:361 Eletrophoretic mobilities 5:839-841 Elettaria cardamonum 21:614; 26:474;27:374 Elettaria sp. 21:599 Eleusine coracana 29:601,617 Eleuterin 4:591,592 Eleutherobia aurea 25:690 Eleutherobin 30:5 as microtubule stabilizing agent 30:5 Eleutherococcus senticosus Harms (A canthopanaxsenticosus) 5:505,514,515,521,523,524,544 Eleven-carbon sugars 4:188 by osmylation 4:188 synthesis of 4:187-190 Eliamid 28:146 cytostatic activity of 28:146 fungicidal activities of 28:146 nematocidal activity of 28:146 Elicitins 25:395,396 Elicitins receptor 25:396 Elicitor activity 25:397 Elicitor-active structure 25:394 Elicitors 25:393,394;27:61 syn-Elimination 11:184,188 [3-Elimination 11:184;24:8,9,10,13,15, 23 antiperiplanar 12:17 of 3-mesyloxy-l-threonate 12:17 stereoselective 12:17 Hfinnig base-mediated 14:291, 292 1,4-Elimination 11:187 Elimination 6:540;16:366,416 by molybdenum (VI) oxodiperoxo complexes 4:344, 345 by Sharpless procedure 4:29,30 enantioselective epoxidation 4:29,30,343-345 of non-functionalised olefins
293
4:344,345 thermal 4:44,45 ~{-Elimination 19:165 [3-Elimination reaction 10:593 Elimination with KN(SiMe3)2 1:440 Elimination-addition mechanism 14:457 Eliminative cleavages 1:618,619 ELISA 15:363-366;30:774 Elkin-Ahn-Houk model 30:437 for asymmetric induction 30:437 Ellagetannins 20:276 Ellagic 20:276 Ellagic acid 23:536,550,746,750; 25:545,938;26:359;27:413,755; 28:280;29:571,579 as inhibitor of PKA 25:550 as inhibitor of PKC 25:550 derivatives of 23:536,550 effects on ACE 29:579 inhibition of Candida albicans aspartic protease 29:751 inhibition of pepsin by 29:571 structure of 28:280 Ellagitannin oligomers 23:395-453 ~3C-NMR data of 428 ~H-NMR data of 23:426 biogenesis of 23:395-453 chemical perspective of 23:395453 classification of 23:398 discovery of 23:395 CD data of 23:433 CD spectroscopy of 431 mass spectroscopy of 423 structure elucidation of 23:423 Ellagitannine 17:360;23:750,752 Elliptically polarized light 2:154 Ellipticine 22:9,27;26:828,829 Ellipticine derivatives 6:510,511, 515,516,520 Ellipticine derived alkaloids 6:506-520 Ellipticine-type alkaloids 5:89,90 Ellipticity 2:153,2:160 Elliptinium acetate 22:28 Elliptinone 2:212,214,754 Elsinan 5:278,754 Elsinoe leucospila 5:278 R-(+)-Eludanolide 19:134 Elymoclavine 11:200
Emaciation 26:690 Emanthidine 26:614 Emarginatine A 23:679 Emarginatine B 23:679 Emarginatine C 23:679 Emarginatine D 23:679 Emarginatine E 23:679 Emarginatine F 23:679 Emarginatine G 23:679 Emarginatinine 23:679 EMBASE 19:758 Embelia schimperi 30:325 5-O-methylembelin from 30:325 Embelin 7:182 Embryolethality 23:577 ofjervanes 23:577 of solanidanes 23:577 of spirosolanes 23:577 Embryonic central nervous system 30:378 role of serotonin (5-HT) in 30:378 Embryonic development 23:563-589 of Veratrum alkaloids 23:563-589 Ememogin 15:143,152,160,175 Emericalla uniquis 25:780 Emericellopsis sp. 21:224 Emetic effect 26:239 Emetine 13:92;22:29 (-)-Emetine 14:565 synthesis of 14:565 (+)-Emetine 18:330 amoebicidal activity of 6:485 EMIBD 24:954-956 bioactive compounds of 24:954-956 bioactivity of 24:954-956 Emicarpus anacardium L. 22:532 Emmons-Horner-Wadsworth 29:471 carbaaldopyranoses synthesis 29:471 Emodin 9:400;22:467-480,608,609,610, 617,620,623 ;23:798;25:543,544,547, 546;26:637 ;30:306 structure of 30:306 Emodin-8-D-glucoside 22:609,610 Emodin-8-O-fl-D-glucoside 22:617,618,619
294
Emphibian skin 27:797 bombesin analog from 27:797 Empidonnax hammondii 5:836 Enamide photocyclization 3:404-406 non-oxidative 3:404-406 reductive 3:407-410,414 Enamide-aldehyde cyclization 14:772-779 Enamidines 6:430,431 Enamine formation 1:452 Enamine related substrates 18:315-386 Enamine-aldehyde cyclization 14:785-787 (+)-corynoline by 14:785-787 (+)-11-epicorynoline by 14:785-787 (+)- 11-epiisocorynoline by 14:785-787 (+)-isocorynoline by 14:785-787 Enamines 14:791-793 acid-catalyzed 14:791-793 cyclization 14:791-793 reactions with acetylenes 3:95,96 singlet oxygen cleavage of 8:261 [3-Enamino imine substrate 18:343,366 [3-Enaminoesters 14:738 cyclization of 14:738 dehydropyrrolizidines from 14:738 Enaminosulfoxides 6:317,318 in c~-ketoacid derivatives synthesis 6:317,318 Enantio-13-epi-labdanolic acid 25:252 Enantiofacial selection 13:70-73 asymmetric synthesis by 13:70-73 Enantiomeric chiral auxiliary 12:342 Enantiomeric composition 27:374, 377,385 in conifers 27:370 of monoterpenoids 27:370,374 of et-pinene 27:385 Enantiopinifolic acid 25:252 Enantioselective- 6:445,446 epoxidation 6:445,446 fermentative reduction 6:158 hydrolysis 13:54 Michael addition 6:86
oxidation 13:54 reduction 13:54 Enantioselective chromatographic analysis 27:361 Enantioselective hydrolysis 12:337 with Candida cylindracea 12:337 with Pseudomonas sp. 12:337 Enantioselective reactions 16:559 Enantioselective reduction 18:288 Enantioselective synthesis 6:39,40,86, 87,443;12:281,311,312;14:14-17, 546,741,742 ;22:235 ;24:185 ;29:244, 490,492 of (-)-( 1R-8aS)-1-hydroxyindolizidine 12:281 of (-)-slaframine 12:311,312 of (-)-y-rhodomycinone 14:14-17 of (+)-( 1S,8aS)-1-hydroxyindolizidine 12:281 of (+)-stoechospermol 6:39,40 of 2,5-dialkylpyprrolidine ant alkaloids 6:443 of 7,20-diisocyanoadociane 6:86,87 ofepi-lupinamine 14:741,742 of kaurane-type diterpenes 14:546 o f lupinamine 14: 741,742 ofsolenopsin B 6:429,430 of spirovetivane-type sesquiterpene 14:546 of (+)-albicanol 24:185 of carbaoxirose/carbaoxetoses 29:490,492 of Physarum polycephalum 29:244 Enantioselective yeast hydrolysis 12:338 Enantioseparations 27:387 of monoterpenoids 27:387 Enantio-sigmosceptrellin-A 9:28,29 Enantiospecific dehydrogenation 24:742 Enantiospecific reduction 24:742 Enantiospecific synthesis 4:625;12:313, 314,317,318
295 Enantiotopic discrimination 13:60-62 asymmetric synthesis by 13:60-62 Encephalartos 26:1157
Encephalartos friderici-guilielmi 26:1158
Encephalartos longifolius 26:157 Encephalitis 30:408 vaccination against 30:408 Encephalitizoon inteslinalis 26:788 Encephalocele 7:20,21;23:570 Endecaphyllins 27:522 Enders 29:389 steganes synthesis by 29:389 Enders reagent 4:327 Endiyne antibiotic 10:154 Endlicheria dysodantha 26:211 dysodanthin A&B from 26:212 megaphone acetate from 26:212 Endo and exo-bicyclic compounds 10:138,139 Endo benzyloxy group 12:340 Endo-anhydroverticillol 12:182 Endocannabinoid analogues 30:198 as cannabinoid ligand 30:198 Endocrine control 19:628 Endocrine function 27:314 Endocrine system 22:369 10-Endoe endon cyclization 10:219 8-Endoe endon cyclization 10:219 Endogenous abscisic acid 27:322 Endogenous defense signal system 25:397 Endogenous hepatoprotective factor 25:471 Endogenous peptide opioids 30:193 role of dynorphins 30:193 role of endorphins 30:193 role of enkephalins 30:193 role of nociceptin 30:193 role of OLR- 1 30:194 role of opioid receptors 30:193 Endomorphins 30:799 Endomyces spp. 2:323 Endomycopsisfibuliger 5:280,282 Endonuclease 13:290 Endonuclease restriction map 2:354 Endoperoxide rearrangement 4:419,420 Endoperoxide synthase 9:571
Endophytic fungi 21:91;24:933-972 bioactivity of 24:944-950 brine shrimp toxicity of 24:944-950 Endoplasmic reticulum 25:548 Endopolygalacturoase 26:1133 Endoproteinases 25:375 Endoproteolytic proceesing 25:387 ENDOR spectroscopic method 30:540 in free radical studies 30:540 [~-Endorphin 27:802,803 Endorphins 22:23;27:20,72,801 ;30:193 as endogenous peptide opioids 30:193 biological activity of 27:801 Endospermum diadenum 29:100 Endosymbiosis 6:134 Endothelial leukocyte adhesion molecule-1 (ELAM-1) 30:70 expression of 30:70 Endothelin A 25:841 Endothelin antagonism 26:237 Endothelin converting enzyme (ECE) assay 28:699 activity of halistanol disulfate B in 28:699 Endothelin-I 25:841;26:267 Endothelium 30:410 Endothelium-dependent NO/EDFR 30:76 production of 30:76 Endothelium-Derived Relaxing Factor 26:951 Endotoxemia 25:463 Endotoxin-mediated pathway 23:140 Endotoxins 28:518 chemistry of 28:518 Endo-fl-l,6-galactanase 25:438 Endo-fl-galactosidase 25:436 Ene cyclization 1:17,159,294 Ene reaction 10:59 of 17(20) Z/E pregnenes 10:59 intramolecular 3:21;11:91,108; 16:17,246 of acryloyl chloride 16:246 of N-sulfoxyl imines 16:17 metallo-variant of 3:21 of malondialdehyde 6:225,226 Enediyne chromophore 25:796
296
Ene-quinone-methide 5:744,747,749 E-Nerotidol 25:164 Ene-type reactions 1:616,617 Engelhardtia chrysolepis 15:31; 27:18;29:583 huangqioside E from 27:18,35 neoastilbin from 27:18,35 Engler synthesis 14:692-695 Engorged toxicity 28:400 from Hibiscus rosa-sinensis 28:400 from Nicotiana tabacum 28:400 from Ocimum micranthum 28:400 from Quassia simarouba 28:400 fromRicinus communis 28:400 from Salvia serotina 28:400 from Spigelia anthelmia 28:400 from Symphytum officinale 28:400 from Stachytarpheta jamaicensis 28:400 Enkephalins 21:72;22:23;25:533; 27:801 ;30:193,817 analgesic activity of 30:817 as endogenous peptide opioids 30:193 biological activity of 27:801 Enmein 15:173 from Rabdosia lophanthoides 15:173 from Rabdosia sculponeata 15:174 Enmenol 15:172 from Rabdosiajaponica 15:172 Enniatin A&B 26:482 Enniatins 6:219,220,213,519,5339535;13:533 Enoate triol 12:15 enantioselective 12:15 from (-)-quinic acid 12:15 synthesis of 12:15 ENOD40 25:368,379 ENOD40 peptide 25:381 Enol ether 30:441 cleavage of 30:441 Enol ether reaction 4:437 with azetidinone 4:437
enterobacteriaceae 4:196 triheptoses in 4:196 Enol lactone 8:297 Enol silyl C-glycoside 10:342 Enol silyl ether (enolate) 12:160,161, 163,164 3-Enol- 17,21-triacetate 9:416-418 Enol-acetate nucleosides 4:237 synthesis of 4:237 Enolacetylation 30:486 of trienone 30:486 Enolate alkylation 14:738 Enolate Claisen rearrangement 10:340 Enolate formation 10:410,411 LDA-mediated 10:410,411 of 7-1actone 10:410,411 5-Enolpyruvylshikimate 3- phosphate synthase 11:185,187 A2,3Enone 12:25 ~,[3-Enone 30:444 derived from D-mannose 30:444 Enone 8:176-178,181,183-186,191; 11:344 E-Enone 8:177 Z-Enone 8:177 Enone epoxidation 10:36 Enone-alkene photocycloadditions 6:33,34 Enones 10:352-354 Enopeptins 21:374 Enopeptins B 21:409 Enoyl CoA reductase 11:191 from Streptomyces collinus 11:191 Entada 15:191,214 Entagenic acid 25:60 Entamoeba histolytica 6:398,485; 23:473 ;26:836,1063 Entandrophragma 9:102 Entandrophragma utile 9:95 Enterobacter cloacae 12:63;25:258, 259;26:402,1091 Enterobacter sp. 25:170,171 Enterobactin 9:537 Enterococcus faecalis 10:117,400; 20:712 ;25:776,778 Enterococcus faecium 25:776 Enterodiol 26:191
297
Enterofuran 26:191 Enterolactone 5:461 ;26:192 Enterolactone lignans 26:209 Enterolobium contorsiliquum 29:604 Enterolobium EcTI 29:604 Enukokurin 2:262,265 Enveloped virus 21:662,665;30:395,401 inhibitor of 30:395 Enyne 8:277-281 Enyne carbocyclization 12:263 Enzymatic activities 21:168; 24:981-1006,1077 alginasic 24:995-998 amylase 24:995-998 arabinosidasic 24:994-998 cellulasic 24:983-998 chitinasic 24:999-1001 galactosidasic 24:994-998 gelatinasic 24:999-1001 lipases 24:1005 lipasic 24:999-1001 nitrate reductases 24:999-1001, 1005 pectinasic 24:995-998 polysaccharides 24:1003-1004, 1009,1077 proteases 24:1005 redox enzymes 24:983-987,1003 xylanasic 24:983-993 Enzymatic aldol condensation 10:535, 536;11:216 Enzymatic cleavage 21:167 Enzymatic coupling 2:392,394,396, 398,399,401 Enzymatic cyclization 7:100 Enzymatic degradation 27:191-196 of benzoxazinoid acetal glucosides 27:191-194 Enzymatic enantiotopic differentiation 13:624 Enzymatic hydrolysis 6:150;7:268,270; 13:54,56,57 ;16:291 ;21:165 of geniposide 16:291 of diacetylenic allo-xanthin 6:150 of soya bean flour 9:412,413 Enzymatic oxidation 21:499 of sulfides 14:517,518 sulfoxides from 14:517,518
Enzymatic reaction 16:108,110,111 Enzymatic reduction 12:338,58 Enzymatic synthesis 30:423 of oligonucleotides 13:279,280 Enzymatic transesterification 13:55 Enzymatically controlled 11:287 Enzyme 23:377;27:378;30:423,430, 835,840 activity of 27:378 coumarin effect on 23:335,356, 357,353,368,376,393,550,553 for synthesis of carbohydrates 30:423 inhibition of 30:154-156 Enzyme activities 2:389,390,392,394, 396,399;21:748;23:12 Enzyme activity inhibition 21:589 Enzyme catalyzed conversion 2:3.72 Enzyme catalyzed reactions 7:29 Enzyme inhibition 24:845 biological activity 24:845 Enzyme inhibitors 22:29 Enzyme inhibitory activity 21:398,585; 27:850 Enzyme intermediates 27:740 reactivity of 27:740 ENZYME program 17:493-494,500 Enzyme-aided enantioselective acylation 18:428 Enzyme-aided enantioselective hydrolysis 18:426-428 Enzyme-carbohydrate interactions 7:29-86 Enzyme-catalyzed acylation 12:346 Enzyme-catalyzed reactions 9:612,176 Enzyme-inhibitory properties 7:14 Enzyme-linked immunosorbent assay 24:142;26:1125 Enzymic activity 28:257 of plant polyphenols 28:257 Enzymic galactosylation 10:469 Enzymic generation 27:77 oftrihydroxy fatty acids 27:77 Enzymic metabolism 23:12 EPA 30:65 from carp oil 30:65 Epatorenone 5:28-30 Epchrosine 6:505,521
298 Epchrosine (19R,20R-epoxy-apparicine) 9:172,173 (-)-Epedradine A 9:76 Epeolus cruciger 5:223,224,231,253 Epeolus variegatus 5:223,224,231,253 Ephedra sinica 5:505 Ephedra spp. 26:235 ephedradine B from 26:235 Ephedradine A 9:75 Ephedradine B 26:235 /-Ephedrine 18:601 Ephedrine 21:57,84 (-)-Ephedrine 22:279 1-Ephedrine 5:505 Ephedrine 5:751,752 W-Ephedrine 5:752 24-Epi-l a,25(OH)2D2 30:494 binding affinity of 30:494 23-Epi-25-deacetylrifamycine 23:56 10', 1 l'-Epiabsinthin (guaine sesquiterpene dimer) 29:574 effects on HIV- 1 protease 29:574 Epiacetylaleuritolic acid 7:144,145 16-Epiaffinine 9:181,182 19-Epiajmalicine 9:171 (+)-Epialloyohimbane 14:710,711 synthesis of 14:710,711 Epialloyohimbane 25:5,20 Epialpinolide 23:815 (+)- 12-Epiaplysistatin 16:705 synthesis of 16:705 Epiapotrichothecenes 13:520 3-Epi-aristoserratenine 9:185,194 (-)-Epiasarinin 26:260 Epiaschantin 18:552 from Hernandia ovigera 18:552 (+)-Epiaschantin 26:201,267;30:568, 590,595 as platelet aggregation inhibitor 30:594 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:589 1-Epiaustraline 10:567,568 3-Epiaustraline 10:567,568
2-Epiavermectin Bla derivatives 12:15 (-)-Epibatidine 19:69;21:95 synthesis of 19:69 (+)-Epibatidine 19:69 synthesis of 19:69 Epibatidine 21:51;22:18;25:757,791, 792 Epibionts 22:79 24-Epibrassinolide 16:322;18:509,511, 529,530,533,534 24-Epibrassinolide 19:247;25:425,426 3-Epibryonol 22:124 Epi-calyxin B 23:805 Epi-calyxin C 23:806 Epi-calyxin D 23:806 Epi-calyxin G 26:902 7-Epicarminomycinone 14:20 1-Epicastanospermine 10:556 synthesis of 10:556 6-Epicastanospermine 10:567 24-Epicastasteron 18:503,511,514, 529,530,533 24-Epi-catasterone 25:425 by Bayer-Villager oxidation 25:425 (-)-Epicatechin 21:498,499,503; 22:319;23:745,747;25:541 Epicatechin 20:782;22:362,645, 663 ;23:743,749 ;30: 83 as tannin 30:83 (-)-Epicatechin (2R,3R, 5,7,3 ',4'tetrahydroxyflavan-3-ol) 29:579 effects on ACE 29:579 Epicatechin 3-gallate (flavan-3-ol) 29:585 effects on proteasome CHY-like activity 29:585 (-)-Epicatechine gallate 22:319;25:612; 27:416;26:770 Epicatechin-3-gallate 26:359 (-)-Epicatechin-3-O-gallate (flavan-3-ol, gallotannin) 29:579,582 effects on ACE 29:579 effects on collagenase 29:582 effects on MMP (gelatinase) 29:582 Epicatechins 26:748,75] Epicathenamine 9:171 (+)-A2-8-Epicedrene 19:136-137
299 8-Epichromazonarol 15:291,298 Epicinnzeylanol 26:850,853 Epicoccum purpurascens 21:221 Epicodisterol 9:42 Epicorazine A,B 21:221 (+)-3-Epicorynanthediol 14:709,710 synthesis of 14:709,710 13-Epicorynantheidol 25:24 (+)-11-Epicorynoline 14:785-787 cyclization 14:785-788 from corysamine 14:785-787 oxidation of 14:788,789 synthesis of 14:785-787 through enamine-aldehyde 2'-Epicycloisobrachycoumarinone epoxide 26:798 Epidaunomycinone 14:7 7Epidermal growth factor 21:135;25:766 Epidermal growth factor receptor 27:847 Epidermoid carcinoma 25:266 Epidermophyton fluccosum 26:227,228 Epididymal sperum 27:311 14-Epidihydrocochlioquinone B 26:460 Epidihydrophysalin C 20:189,20:247 from Witharingia cocculolides 20:189 4E- 1-Epidihydroridentin 27:567 4Z- 1-Epidihydroridentin 27:567 Epidioxy-substituted non-diterpenes 25:688 Epidithodioxopiperazines 25:901 16-Epi-E-isositsirikine 9:170,171,173 11-Epi-ephedradine A 9:75,76,78 Epiepoformine 4:612,613 synthesis of 4:612,613 Epiepoxydon 4:612 synthesis of 4:612 (-)-Epieudesmin 26:201 Epifrenolicin 4:592,594,595 Epigallocatechin 22:325,362;30:83 as tannin 30:83 (-)-Epigallocatechin gallate (EGCG) 25:470,546 (-)-Epigallocatechin 23:745;27:416 structure of 27:418 Epigallocatechin (413-+8, 2[3-+0-7)epicatechin 29:572
effects on HIV- 1 protease 29:572 Epigallocatechin 26:748;29:585 effects on proteasome CHYlike activity 29:585 (-)-Epigallocatechin 3-O-gallate 29:579,582,585,588 effects on ACE 29:579 effects on collagenase 29:582 effects on MMP (gelatinase) 29:582 effects on PEP 29:588 effects on proteasome CHYlike activity 29:585 (-)-Epigallocatechin gallate 22:319; 27:416,839 Epigallocatechin gallate 30:83 as tannin 30:83 Epigallocathechin-3-gallate 26:755 (+)-11-Epigigantenone 6:555,556 synthesis of 6:555,556 Epigloeosporone 9:241-243 synthesis of 9:241-243 7-Epigloeosporone 9:245 Epiguadalupol 6:30 from Laurencia snyderae 6:30 from perforenone 6:30 synthesis of 6:30 Epihaemanthamina 20:352 10-Epihengazole A 26:488 4-Epihenryine A 15:114,121,128,172 19R-Epiheyneanine 9:171 20-Epi-ibophyllidine 9:190,192 E(+)-I 1-piisocorynoline 14:785-787 cyclization of 14:785-788 from corysamine 14:785-787 oxidation of 14:788,789 synthesis of 14:785-787 (-)- 10-Epi-isokalihinol 25:4,856 4-Epi-isopimaric acid 15:172 Epiisopodophyllotoxin 24:762,766,771 synthesis of 24:762,766 13,14-bis-Epijeunicin 8:15,16 (+)- 10-Epijujenol 16:264 synthesis of 16:264 Epijuvabione 22:387 (-)-10-Epi-kalihinol H 25:854 (-)-lO-Epi-kalihinol I 25:856 3-EpikarounidioI 22:124
300
Epilachna varibestis 7:396; 22:398;30:333 (-)-Epilamprolobine 15:524 from Sophora tomentosa 15:524 (+)-Epilamprolobine 18:367 (+)-Epilamprolobine N-oxide 15:524 from Sophora tomentosa 15:524 7,8-Epilantolactone 10:187 Epilepsy 21:19;22:510-535,720,742 Abrus precatorius L for. 22:510 Acalyphafruticosa Forsk. for 22:510 Acorus calamus L. for 22:510 Albizzia harvey Fourn for 22:511 Allium cepa L. for 22:511 Aloe vera L. for 22:511 Alstonia scholaris R. Br. for 22:512 Alstonia venenata R. Br. for 22:512 Anagallis arvensis L. for 22:512 Annonidium monni for 22:512 Arisalema heterophyllum B. for 22:512 Arrabidaea platyphylla for 22:513 Asparagus recemosus for 22:513 Bacopa monnieri L. for 22:513 Balsamodendron sp. for 22:513 Barringtonia recemosa for 22:514 Basilicum polystachyon for 22:514 Benincasa cerifera for 22:514 Benincasa cerifera savi for 22:514 Benincasa hispida for 22:513 Bersama abyssinica for 22:514 Bombax malabaricum DC. for 22:514 Bramia monnieri L. for 22:513 Brassica nigra L. for 22:514 Butea monosperma (Lam.) Kuntze for 22:514 Canscora decussata for 22:515 Canthium gueinzii for 22:515 Cardamine pratensis L. for 22:515 Cedrus odollam for 22:516
Centipeda orbicularis for 22:516 Cinnamomum camphora for 22:516
Cissus integrifolia for 22:517 Citrus maxima for 22:517 Cocculus sermentosus for 22:517
Colchicum luteum for 22:517 Colebrookea oppositifolia for 22:517
Coleus aromaticus for 22:517 Conium maculatum L. for 22:517
Conthium guiinzii for 22:515 Cucumis colocynthis L. for 22:518
Cucumis sp. L. for 22:518 Cynodon dactylon L. for 22:518 Cyperus esculentus L. for 22:518 Cyperus rotundus L. for 22:401, 518
Daturafastuosa L.for 22:519, 742
Datura metel L. for 22:519 Daucus carota W. for 22:519 Deinbollia borbonica for 22:519 Delphinium denudatum Wall for 22:519
Dichrostachys cinerea L. for 22:519
Diospyros usmabarensis F. White for 22:520
Ekebergia senegalensis A. for 22:520
Elaeocarpus sphaericus for 22:520
Elaeocarpus tuberculantus for 22:520
Erythrina stricta for 22:520 Euphorbia nyikae Pax. for 22:520
Euphorbia tirucalli L. for 22:520 Euphorblaceae phyllantus for 22:720
Excoecaria agallocha L. for 22:520
Ferula alliacea for 22:521 Ferula galbaniflua for 22:521 Flemingia strobilifera for 22:521
301
Flueggea virosa for 22:521 Galium verum L. for 22:521 Galphimia glauca for 22:521 Gos~ypium herbaceum L. for 22:521,522
Gyrocarpus americanus Jacq. for 22:552
Helichrysum setosum for 22:522 Hemidesma indicus R. for 22:522
Herpestis monniera for 22:513, 522
Hesperethusa crenulata for 22:522
Hiptage benghalensis for 22:522 Hoslundia opposita for 22:523 Humboldtia vahliana for 22:523 Hyoscyamus niger for 22:523 Ilex aquifolium L. for 22:523 Impatiens repens for 22:523 Indigofera tinctoria L. for 22:523
lpomoea hederaceae L. for 22:523
Ipomoea hispida for 22:523 Launaea cornuta for 22:524 Leonurus cardiaca L. for 22:525 Limonia acidissima L. for 22:525
Limonia crenulata for 22:525 Lobelia inflata L. for 22:525 Maerua angolensis DC. for 22:525
Mangifera odorata L. for 22:525 Martynia annua L. for 22:526 Melissa officinalis L. for 22:526 Moghania strobilifera L. for 22:526
Moringa oleifera for 22:526 Musa paradisiaca L. for 22:526 Mylitta lapidescens for 22:527 Myrmicacin for 22:81,527 Nardostachys jatamansi DC. for 22:527 Nerium oleander L. for 22:527 Ocimum basilicum L. for 22:527 Origanum vulgare L. for 22:528 Ormocarpum kirkii for 22:528 Paeonia emodi for 22:528
Paeonia officinalis L. for 22:528 Palisota ambigua for 22:528 Paris polyphylla for 22:528 Phoenix reclinata for 22:529 Phyllanthus emblicata k. for 22:529
Phyllanthus urinaria L. for 22:529
Pongamsa glabra Vent. for 22:530
Psidium guyava L. for 22:530 Punica granatum L. for 22:530 Quercus infectoria for 22:530 Rabidaea platyphylla for 22:513 Rauwolfia serpentina L. for 22:531
Rauwolfia vomitoria L. for 22:531
Ruta graveolens L. for 22:531 Sapindus mukorossi for 22:531 Sapindus trifoliatus L. for 22:531
Saussurea lappa for 22:531 Scutellaria galericulata L. for 22:532
Semecarpus anacardium L. for 22:532
Solanum carolinense L. for 22:532
Solanum incanum L. for 22:532 Solunum xanthocarpum for 22:532
Stephania cepharantha for 22:533
Strychnos cinnamomifolia for 22:533
Synaptolepis kirkii for 22:533 Tamarix articulata for 22:533 Tamarix gallica L. for 22:533 Taxus baccata L. for 22:533 Terminalia chebula for 22:533 Trema guineensis for 22:534 Trema orientalis for 22:534 Trichosanthes anguins L. for 22:534
Valeriana hardwickii for 22:534 Valeriana officinalis L. for 22:534
Valeriana wallichii for 22:534
302
Xanthoxylon hostile for 22:535 Ximeni caffra for 22:535 Ximenia caffra for 22:535
Epileptic affections 22:517 Coleus aromaticus for 22:517 Epileptic attacks 22:526 Martynia diandra for 22:526 Epileptic children 30:377 Epileptic convulsive seizures 22:512 Annona muricata L. for 22:512 Epileptic fits 22:520,522,526,531 Elaeocarpus ganitrus for 22:520 Hiptage benghalensis for 22:522 Sapindus emarginatus L. for 22:531 Epileptic seizure 22:525 Leucas lavandulifolia for 22:525 Epilobium capense 23:404 Epilupinine 14:732-737 diastereoselectivity of 14:732737 from piperdine acetic acid 14:738 stereochemistry of 14:734 synthesis of 14:732-737 (+)-Epilupinine 16:467 synthesis of 13:483,484;16:467 Epimagnolin 18:552 from Hernandia ovigera 18:552 (+)-Epimagnolin 26:201 ;30:568, 590,595 as platelet aggregation inhibitor 30:594 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:589 (+)-Epimalyngolide 19:494 13-Epi-manool 25:252 Epimephrine 25:896 Epimerase 11:195,196 Epimeric 2,3-epoxy brassinosteroids 18:512 synthesis of 18:512 (22S,23S)-Epimeric 24-epicastasterone 18:509 Epimerization 6:558,559,367
Epi-Methyltrineracetal 30:708 structure of 30:708 (19R)-Epimisiline 5:173 (19S)-Epimisiline 5:173,174 Epimodhephene 13:39 Epimukulol 10:25-29 Epinephrine 25:516,536,538,896 L-Epinephrine 27:754 Epingaione 28:402 growth regulatory activities of 28:402 Epinodosin 15:171 from Rabdosia gaponica vat. glaucocalyx 15:171 from Rabdosia henryi 15:172 from Rabdosiajaponica 15:172 from Rabdosia sculponeata 15:174 Epinodosinol 15:172 from Rabdosiajaponica 15:172 from Rabdosia parvifolia 15:173 8-Epinonactic acid 18:235 (-)-7-Epi-nootkatone 16:239 Epipactis helleborine 30:405 (+)-20-Epipandoline 9:190 3-Epi-paraherquamide A 28:354 antihelmintic activity of 28:354 Epipedobates tricolor 19:66,146; 25:791;27:247 Epiperiplanol-13-benzoate 6:539 (+)Epiphyas postvittana 26:231 Epipinoresinol 20:620 (+)-Epipinoresinol 26:201 dimethyl ether 26:201,241 (+)-Epipinoresinol dimethyl ether 26:241 as PAF-induced inhibitor 26:241 Epipinorisenol 4'-O-glucoside 5:490, 491,494 (+)-Epiplasin-B 25:852 Epipodophyllotoxin 18:561,597-601; 26:155,210 synthesis of 18:561,597-601 4-Epipodophyllotoxin 26:193 Epipodorhizol 26:192 Epipolases kushimotoensis 25:898 Epipolasin 21:330 Epipolasin-A 21:351,354;25:853
303
Epipolasis kushimotoensis 25:853;
28:662 [3-phenylethylamine of 28:662 epipolasins A of 28:662 epipolasins B of 28:662 Epipolasis sp. 28:699 Epipolythiodioxopiperazines 25:839 Epipomolic acid (triterpene) 29:574 effects on HIV- 1 protease 29:574 14-Epipseudovincadifformine 19:105, 107 20-Epipseudovincadifformine 19:105, 107 (+)-5-Epipumiliotoxin 18:340 synthesis of 18:340 Epiquinine complexes 25:347 (+)-Epiresinol 26:268 16-Epi-rhazinaline 9:195 Epirubicin-4'-O-[3-D-glucuronide 21:175 13-Epi-sclareol 25:252;26:397 xylopyranoside 25:252 (-)-Episesamin 26:201 (+)-Episesamin 26:260 Episesartemin-B 7:219 Episesmin 26:246 (-)-6-Epislaframine 18:386 Epistatine 12:430,431 Episteganangin 26:196,216 Episterol 25:415 (-)-I-Epi-swainsonine 16:675 synthesis of 16:675 16-Epitacamine 9:179,180 Epitaondiol 17:8;25:690 (+)-5-Epitashiromine 18:345,353 22R-Epitautomycin 18:294 24-Epi-teasterone 25:422,433 12-Epi-teucvidin 601 13C-N MR data of 23:602 ~H-NMR data of 23:602 Epitheaflavic acid 28:274 formation of 28:274 Epithelial NO synthase 25:525 Epithelizing effect 26:335 Epithienamycin A,B,E,F 4:434 Epithienamycin C,D 4:434,450 7-Epithydroxylogonin 20:62
10-Epitrewiasine 70 14-Epi-triptolide 23:684 24-Epi-typhasterol 25:422,423
1-Epivalidamine 13:197,198 Epivincadine 14:634,636 synthesis of 14:634,636 Epiyangambin 26:242 as PAF-induced inhibitor 26:242 (+)-Epiyangambin 26:201 ;30:569,590, 593,595 activity in human cancer cell lines 30:589 activity in murine cancer cell lines 30:589 as platelet aggregation inhibitor 30:594 cytotoxic effect of 30:589 use of soft agar transformation assay 30:593 16-Epi-Z-isositsirikine 9:171 (+)-Epi-[3-necrodol 16:147 Epi-13-necrodol 16:153 (+)-Epi-13-santalene 16:131 Epobenzoxocin system 4:358 synthesis of 4:358 Epoformine 4:339-354,396,505 epoxidation 4:339-354,396,505 asymmetric 4:339-345 Sharpless asymmetric 4:496 stereospecific 4:505 synthesis of 4:612 Epomuricenin 17:277 Epomuricenin A 18:212,219 Epothilione 26:811 ;30:5 as microtubule stabilizing agent 30:5 Epothilone A 26:810 Epothiolones 24:406 as anti-fungal agents 24:406 Epoxidase 7:103,104 Epoxidase-epoxide hydratase system 7:107 C (2,3)-~-Epoxidation 10:39,40 ofallylic alcohols 10:39,40 Sharpless 10:39,40 with VO (acac)2-TBHP 10:39, 40 ct-Epoxidation 11:383
304 Epoxidation 11:470;16:571;24:30-32, 62,63,65,66,68,72,73,87,110-112, 175,188-190;27:753 enantioselective 16:571 hydroxy-directed 19:259 ofallylic alcohol 16:342 of cannabidiol 19:236 of enol 19:259 ofenolsilyl ether 16:332 of ketone 8:182 of limonene 16:229 of methyl perillate 6:545 of stigmasterol 16:334 of vinylsilane moiety 16:268 of c~,[3-unsaturated ketones 16:571 of c~-patchoulene 16:151 of styrene 27:753 regioselective 1:436,439 Sharpless 12:236 Sharpless asymmetric 1:278,279, 507,508,510 stereoselective 8:179-182; 16:349;19:372 with alkaline hydrogen peroxide 16:349 with t-BuOOH-KH 8:180-182 with t-BuOOH-Ti (OPr-i)4' 3:100,101 with Vo(acac)2/t-BuOOH 1:436,439 Epoxide alkylation 14:746 Epoxide hydrolase (EH) 23:476;25:150 Epoxide opening 1:439 acid catalysed 1:439 cuprate mediated 1:536 organo cuprate mediated 1:536 with cuprate 1:456,457 with dimethyl cuprate 1:523 with Redal 1:538 Epoxide rearrangement 6:136,550,551 ot-Epoxide reduction 4:418 Epoxide-furanoid rearrangement 6:162 Epoxides 1:681-684;2:4;27:79,80 generation of 27:80 oflinoleic acid 27:80 Epoxidisation system 7:105 Epoxisolancerotetrol 5:736
ent-15,16-Epoxy-9aH-labdane- 13( 16)-
14-diene 3fl,3a-diol 25:276 2,3-Epoxy alcohol 14:569 N-benzoylcarbamate from 14:569 pyrrolidine derivative from 14:570 with benzoyl isocyanate 14:569 13,~'-Epoxy alcohols 10:412 Epoxy allylic ether 10:590,591 cyclization 10:590,591 from D-ribose 10:590 synthesis of 10:589,590 Epoxy amide 12:161,162 4-benzoyloxy-b-lactam 12:161,162 from L-threonine 12:161,162 Epoxy peroxide 4:422,423 Epoxy resins 9:370 Epoxy sterol 17:22 Epoxy sulfoxide 6:310 1,2-Epoxy- 1-(2-methoxyphenyl)-2-(4methoxyphenyl)ethane 30:223 structure of 30:223 1[3,10c~-Epoxy-1,10H-desacetyllaurenobiolide 27:565 10,13-Epoxy- 11-methyloctadeca- 10,12dienoic acid 26:69 413,5[3-Epoxy- 17[3-hydroxyestran-3-one 5:449 513,6[3-Epoxy-1-oxocholist-2-ene-4[3 -ol 20:245 5[3,613-Epoxy-1a, 14(x,17[3,20tetrahydroxy-with-24-enolide 20:245 5 [3,613-Epoxy-27-hydroxy- 1,4dioxowitha-2,24-dienolide 20:234 (+)-7,8-Epoxy-2-basemen-6-one 16:226 Epoxy-3 [3,4a, 10a-trihydroxyguaian6or, 12-olide 27:579 1[3,10o~-Epoxy-3[3-hydroxy-7o~,11(xHgermacra-4Z-en- 12,613-olide 27:563 2~,5-Epoxy-5,10-dihydroxy-6~angeloy-loxy-913-isobutyloxygermacran-8c~, 12-olide 29:89 activity in iNOS assay system 29:89
305 activity in NFkB assay system 29:89 7c~,8ot-Epoxy- 6 c~-hydroxyabieta9(11), 13-dien- 12-one 29:99 activity in EBV assay system 29:99 3,4-8c~-Epoxy-8-deoxycumambrin 27:577 9,10a-Epoxy-9,10-seco-abieta-8,11,13trien-18-oic acid 29:99 activity in EBV 29:99 (20( R),24)S- Epo xy-9fl, 19-cyc lo lanostan3fl,16fl-25,tetrol 25:217 Ent-8a,14c~-Epoxyabiea- 11,13(15)dien- 16,12-olide (jolkinolide A) 9:283,284,290 ?,6-Epoxyacrylate 21:412 19R,20S- 19,20-Epoxyakuammicine (stictine) 9:192 ot,13-Epoxy-aldehyde 30:473 synthesis of 30:473 Epoxyaldehydes 27:82 generation of 27:82 hydrolysis products of 27:82 cis-c~,f3-Epoxyaldehydes 30:473 Epoxyalkyl glycosides 7:39 4 '(R )-3 '-Epoxyangeloyloxy-4 '-acetoxy3'-4'-dihydroseselin 27:429 19R-20R-Epoxy-apparicine (apparicine) 9:172,173 9a,11 a-Epoxycholest-7-ene 313,5c~,6f3tetrol-6-acetate 5:410 19',20'-Epoxy-conoduramine 5:128 (20(S),24)R-(Epoxycycloartane) 25:227 20,24-Epoxycycloartane derivatives 27:449 1c~,1013-Epoxydeacetyl laurenobiolide 27:564 3,4-Epoxydehydroleucodin 29:90 activity in NFkB assay system 29:90 Epoxydibenzocyclooctene 30:226 Epoxydihydroartemisitene 22:161 15 [3,20[3-Epoxydihydrocatharanthine 14:811,871,872 leurosine from 14:811,871,872 N-oxide derivative of 14:811 with vindoline 14:811,871,872
Epoxydilactone 17:608 Epoxydon 4:612 synthesis of 4:612 2,3-Epoxyeleganolone 18:713 or, [3-Epoxyenone 14:678-681 l[3,2f3-Epoxy-enone intermediate 5:447 3,20-Epoxy-ent-kaurenes 15:136 24,28-Epoxyergost- 5-ene- 3 [3,7ct-diol 20:476,477 Epoxyfatty acid 23:341 Epoxyflabellin 27:578 (7S)-4~3,5a-Epoxygermacr- 1( 10)E-en213,613-diol 29:88 activity in PLA assay system 29:88 activity in TPA assay system 29:88 Epoxyguaianolide 14:362 16,23-Epoxyhalosta-7,24-dien-3 ~-ol 7:277 Epoxyindenone 1:189 Epoxyjaeschkeanadiol 5:724,725,731, 732,735 Epoxyketone 15:167 Epoxyketonucleosides 4:248 synthesis of 4:248 8,13-Epoxy-labd-14-en-oic acid 25:249 (E)-8 [3,17-Epoxylabol- 12-ene- 15,16-dial 23:798 Epoxylactone 17:10 6,7-Epoxy-Lat A 25:874 6,7-Epoxylinalool 25:141 Epoxylobatrenol 21:276 (S)- 1,2-Epoxylycopene 20:593 1,2-Epoxylycopene 20:593 413,15-Epoxymiller-9E-nolide 29:89 activity in NFkB assay system 29:89 activity in TNFc~ assay system 29:89 4[3,15-Epoxymiller-9Z-enolide 29:89 activity in NFkB assay system 29:89 Epoxy-nucleosides 4:225 Epoxypironetin 30:27,28 as mitotic arrester 30:27 effect on G2/M phase 30:28 structure of 30:28
306
7,20-Epoxyroyleanone 20:670 Epoxysantamarine 27:556 1,2-Epoxy-S-carotene 20:593 Epoxysesquipellandrene 8:58 synthesis of 8:58 Epoxyshikoccin 15:163-165,174 22,23-Epoxysteroids 15:48 24,25-Epoxywithanolide D 20:246 6 [3,7[3-Epoxywithanone 20:204 7,8-Epoxyzahavin A 29:103 activity in AOS bioassay system 29:103 Epoxy-13-carotenes 30:840 EPR Spectroscopy 25:340 Epstein-Barr virus (EBV) 10:4;12:234, 390,395 ;22:616;24:215,849;25:45; 30:394,592 in raji cells (EBV genomecarrying human lymphoblastoid cells) 30:592 Epstein-Barr virus early antigen 21:642; 24:215-217;25:46;30:592 activation inhibition of 30:592 inhibition of 25:46 Epstein-Barr virus inhibition 30:560 due to lignans 30:560 due to isoquinoline alkaloids 30:560 Equatorial side-chain 27:341 Equisetin 28:121 antibiotic activity of 28:121 cytotoxicity of 28:121 HIV inhibitory activity of 28:121 ER ryanodine receptor Ca2+ channels 25:517 Eragrostis curvula 26:469 pyrocathecol from 26:469 Erbstatin 15:441 Ercalcidiol (25-hydroxyvitamin D2) 11:381 Ercalcitriol (1 c~,25-hydroxy vitamin D2) 11:381 Eremane diterpenes 15:271-274 (-)-Eremanthin 14:368 Eremanths elegnus 24:6 Eremanthus glomerulatus 7:427 Eremanthus mattogrossensis 29:90
Eremmophla aureonontata 5:223,225,253 Eremoacetal 15:238 Eremofrullanolide 2:280,281 (+)-Eremolactone 15:252,271 synthesis of 8:425 from Eremophilafreelingii 15:252,271 from Eremophilafraseri 15:252,271 synthesis of 15:272 Eremophila 15:225-282 Eremophila abietina 15:227 Eremophila alternifolia 15:225,232 Eremophila caerulea 15:227,281 (+)-fenchone from 15:227 oleanolic acid from 15:281 ursolic acid from 15:281 Eremophila clarkei 15:253 Eremophila cuneifolia 15:227,248 Eremophila dalyana 15:225,227 Eremophila decipiens 15:263 Eremophila dempsteri 15:227,254 Eremophila drummondii 15:244,248 (+)-calamenene from 15:244 serrulatane from 15:259 (+)-spathulenol from 15:248 Eremophila duttonii 15:225 Eremophila elderi 15:225 Eremophila exilifolia 15:252 Eremophilafoliosissima 15:255 Eremophilafraserii 15:248,252,271 Eremophilafreelingii 15:252,271 eremolactone from 15:252,271 freelingyne from 15:233 Eremophila georgei 15:269,271 Eremophila gilessi 15:225 Eremophila glutinosa 15:252 Eremophila granitica 15:254 Eremophila inflate 15:229 Eremophila interstans 15:245,247 Eremophila latrobei 15:229,232,258 biflorin from 15:258 Eremophila longifolia 15:225 Eremophila maculata 15:226,229 Eremophila miniata 15:229 Eremophila mitchelli 15:226,281 Eremophila paisley 15:248 Eremophila petrophila 15:252
307
Eremophila platycalyx 15:281 Eremophila racemosa 15:248 (+)-spathulenol from 15:248
Eremophila rotundifolia 15:233 freelingyne from 15:233
Eremophila scoparia 15:227,232,244 Eremophila serrulata 15:257,259 Eremophila spp. 8:423 (+)-isoeremolactone from 8:423
Eremophila virgata 15:245 Eremophila viscida 15:260
Eremophilane sesquiterpenes 6:554-556 Eremophilanes 7:214,216,152,227,243 Eremophilane-type sesquiterpene 18:639 Eremophilanolide 20:660 7-epi-Eremophilene 15:250 Eremophilone 10:436,437 Claisen rearrangement by 10:436,437 from Eremophila mirchelli 15:238 synthesis of 10:436,437;15:243 stereoselective synthesis of 15:240 Ergine 25:531 Ergocalciferol (vitamin D2) 9:510,521 Ergoclavine 21:91 Ergocornine 21:68 r 4:605,606 synthesis of 4:605,606 Ergolide 29:90 activity in COX assay system 29:90 activity in NFkB assay system 29:90 activity in iNOS assay system 29:90 Ergoline alkaloids 25:706 Ergometrine 21:68,91,96,98,102,109 Ergonovine 13:631;21:488 from Clavicieps purpurea 13:631 Ergosine 21:68 Ergost-5,24 (28)-diene-313,7c~-diol 20:476,477 Ergost-5-en-1 c~,313-diol 11:381
Ergo st-5 -ene- 313,7r tetrao 1 20:476 Ergosta-5,24 (28)-diene-3 [3,713-diol 20:477 Ergostane 16:332;25:49,61 Ergosterin (ergosterol) 9:509,510 Ergosterol 5:406,261,322,509;9:447; 22:59;28:570,572 ;30:489,506,508 as antitumor substance 28:570 effect on neovacularization 28:572 from lanosterol 30:506 ozonolysis of 30:489 Ergosterol biosynthesis 30:485 Ergosterol derivative 30:506 22,23-dihydroergosterol (provitamin D4) as 30:506
24-epi-22,2 3-dihydroergosterol
as 30:506 Ergosterol esters 9:456 Ergosterol mesylate 18:509 Ergosterol mutants 25:304 of Nenrasapora crassa 25:304 Ergosterol peroxide 25:61 Ergosterol-5,8-peroxide 7:218 from Artemisiafeddei 7:218 Ergot 21:91 Ergot alkaloids 11:199-207; 21:57,68,91 ;22:247 biosynthesis of 11:199-207 Ergotamine 13:631 ;21:68,91, 488;25:531 Ergothioneine 25:813 Ergovaline 21:68 Ergoxanthine 20:282 Eria ravanica 23:522 Erica andevalensis 22:428;25:612 myricetin-3-O-D-galactoside from 22:428 Ericaceae 25:246 Erigeron philadelphicus 26:436 Eriobotryajaponica 17:115,118-119; 19:247 Eriocalxin A,B 15:176 Eriocitrin 23:747;26:744;29:579 effects on ACE 29:579 Eriodictyol 30:286 13C-NMR data of 30:286
308 Eriodictyol-3',4'-dimethylether 30:746 structure of 30:746 Eriodyctiol 22:351;26:757 Eriosema compound B (prenylated xanthone) 29:579,581 effects on ACE 29:579 effects on NEP 29:581 Eriosema tuberosum 29:579 Erithrodiol 20:705 Erithrodiol-28-acetate 20:707 Erivanin 7:232;27:51 3-epi-Ervafolidene 5:129 Ervafolidine 5:129 Ervafoline 5:129,172 Ervahanine 5:123 Ervahanine C 5:129 Ervatamia coronaria 5:135,136, 158,171,172 Ervatamine 5:125 20-epi-Ervatamine 5:127 Ervatamine-type alkaloids 5:80-82 19,20-dehyroervatamine 5:81 ervatamine 5:80-82 20-epi-ervatamine 5:81 isomethuenine 5:81 methuenine 5:81 methuenine-Na-oxide 5:81 6-oxo-methuenine 5:81 silicine 5:81 6-oxo-16-epi-silicine 5:81 20-epi-silicine 5:81 iso-6-oxo-silicine 5:81 Ervaticine 5:87,88,124,135,136 Ervima coli 25:220,258,259,394, 450,821,928 Ervincidine 13:393 Ervinidinine 9:190 Ervitsine 5:126 Ervitsine-type alkaloids 5:81,82 Erwinia 4:434 Erwinia amylovra 25:394 Erwinia carotovora 25:394 Erwinia chrysanthemi 25:394 Erwinia herbicola 17:637 Erybidine 6:478 synthesis of 6:478 Erycibe elliptilimba 21:751 Erycibe obtusifolia 21:751 baogongteng A from 21:750
Erylus formosus 26:80,85 Eryocalyxin A 15:171 Eryocalyxin B 15:171 from Rabdosia eriocalyx 15:171 from Rabdosia eriocalyx var. laxiflora 15:171 Erysodienone 3:468 synthesis of 3:468 Erysodine 3:455;21:52 Erysotinone 3:478 Erysotramidine 3:471-476 synthesis of 3:471-476 Erysotrine 3:470,474,475 synthesis of 3:470,474,475 Erytharbine 3:476 synthesis of 3:476 Erythema infectiosum 30:394 Erythraline 3:474 synthesis of 3:474 Erythramine 3:455 Erythratidine 3:455 Erythratidinone 3:455 Erythrina 3:455-493 Erythrina abyssinica 29:781 Erythrina arborescens 3:455-493 Erythrina berteroana 7:417 Erythrina burana 20:496 Erythrina caffra 29:604 Erythrina crysta-galli L. 3:476 Erythrina ETI-a ETI-b 29:604 Erythrina isoquinoline alkaloids 25:528 dehydro-fl-erythroidine 25:528 erysinine 25:528 erysotrine 25:528 erythratidine 25:528 a-erythroidine 25:528 fl-erythroidine 25:528 Erythrina latissima 29:604 Erythrina lithosperma 3:479 Erythrina melinoniana 22:27 Erythrina stricta 22:520 for epilepsy 22:520 Erythrina type 11:229 Erythrina variegata L. 22:520; 29:598,604 Erythrinan-3-one 6:477,478 Erythrinane skeleton 1:327 synthesis of 1:327
309
Erythrinin B 28:229 biological activity of 28:229 D-Erythritol 6:357,358 Erythritol 9:288 Erythro compounds 12:415,416 (15S,16S)-Erythro diasteromer of pumiliotoxin B 12:294 Erythro ethyl [3-hydroxy-[3-(2- piperidyl) propanoate 12:279 Erythro-2-amino alcohols 12:430,431 Erythrodiol 22:126;25:57,60,64;29:586 effects on LELA 29:586 Erythro-glycal 10:341 D-Erythro-hexofuranose 6:376 [3-Erythroidine 3:455-456 Erythroidine alkaloids 3:487,488 synthesis of 3:487,488 Erythro-monopivaloate 23:188 Erythromycin 5:613 Erythromycin A 11:196,197;22:265 biological activity of 12:48 from (9S)-9-dihydroerythronolide A 12:53,54 total synthesis of 12:53,54 X-ray crystal studies of 13:156 Erythromycin A aglycone 3:233 Erythromycin B 11:196,197 Erythromycin-9-oxime 13:160,161 Beckmann rearrangement of 13:160,161 Erythromycylamine 13:170,171 Erythronolide 13:155,156 Erythronolide A 3:233-278,280 synthesis of 11:152,153,157 Erythronolide A enol ether 13:165 Erythronolide A seco-acid 11:154-156 synthesis of 11:154-156 Erythronolide B 16:660-661 by dioxanone-to-dihydropyrane enolate Claisen rearrangement 10:340 seco acid of 16:660 synthesis of 3:278-280;16:660661 D-Erythropentofuranose 6:365,366 D-Erythropentose 6:360,463,364 Erythropoietic protoporphyria 30:524 use of[3-carotene 30:524
Erythropoietin (EPO) 29:547 antibodies against 29:547 as hormone 29:547 in red blood cells production 29:547 inhibition of 29:548 oxidation of 29:547 periodate oxidation of 29:548 reaction with lectins 29:548 reaction with serum 29:548 recombinant type of 29:547 structure of 29:547 Erythrose 4-phosphate (E4P) 23:83,741 Erythroskyrine 21:413 D-(+)-Erythro-sphingosine 192 L-(-)-Erythro-sphingosine 192 Erythroxanthin sulphate 30:526,527 structure of 30:527 Erythroxylaceae 22:718,720 Erythroxylon 21:488 Erythroxylon monogynum 10:180 Erythroxylum spp. 22:520,718,721 D-Erythro-[3-methylaspartic acid 9:496 Esbericum 22:698 Escallonia spp. 29:572 Eschenmoser reaction 8:211 Eschenmoser ring contraction 9:601,602 Eschenmoser-Claisen rearrangement 10:417,419-421,427,428 Eschenmoser's salt 4:665,10:164,19:94 Escherichia chrysanthemi 25:394 Escherichia coli 4:433;5:367,429,434; 7:39,44,46,50,52,54 ;9:293,308,537,5 92,593,596,603,604,606;8:102;11:18 2,214;12:63,95-109;13:157,162,164, 261,262,283;17:378;18:709,722,727, 921 ;19:601 ;20:712;21:174,175,299, 573,600;22:623,627;23:67,137,235, 474,533;24:713;25:257,319,765,775, 925,948;26:330,331,333,402,556, 605,802,1092,1093,1135,1263,1269, 1271,1272,1274,1278;27:305; 28:519;30:739,843 antibacterial activity against 30:739 antifungal activity against 30:739 biological activity of 30:843
310
Escherichia coli BFI-ATPase 10:439 Escherichia faecilis 25:259 Eschscholtzia 27:163 Eschscholtzia californica 27:159 Eschweiler-Clarke methylation 10:84, 165 Eschweiler-Clarke reaction 1:203, 384,385 Escins (triterpene saponin) 29:574 effects on HIV- 1 protease 29:574 Escobedria scabrifolia 30:528 azafrin from 30:528 Esculetin 5:515,517,521,579;22:168; 23:356;26:314,315,317,318,330-334, 336-340,342,344 Esculin 5:515,521;26:317,318,330-342 Eseramine 21:84;25:536 as immunosuppressive drug 25:536 Eserethole 1:326 synthesis of 1:326 (-)-Eserethole 14:637,638 (-)-physostigmine from 14:637,638 synthesis of 14:636-638 Eseridine 25:536 as immunosuppressive drug 25:536 Eserine 21:84,753 (-)-Esermethole 14:639 synthesis of 14:639 (-)-Estafiatin 14:358,359 ESP 21:555 Esperamycin 10:150,153 Espintanol 26:797,798,807 Espulegol 23:342 Essential oil 21:596;24:232;28:412,415, 427,390,408,421,426;30:605,607 acaricidal activity of 28:412,427 against sarcoptic mange 28:415 antimicrobial activity of 21:235 from limonene 30:607 from nonane 30:607 from c~-gurjunene 30:607 from a-pinene 30:607 from ~-pinene 30:607 lethality tests of 28:392
of hypericum 30:605 use as bactericides 28:390 use as fungicides 28:390 use as insecticides 28:390 Estafiatin 1:546,558,235 Esteinascidin 25:825 Ester enolate Claisen rearrangement. 3:236,246,259,261-265,267-270, 274-276,278-280;14:497 Ester epimerization 1:466 Ester exchange reaction 4:519 Ester type glycoside linkage 7:154,155 Esterase 13:303 Esterification 4:91,92,276,292,391,409, 412,413 Estogen-sensitive tissues 5:447 Estradiol 3:435;6:222 synthesis of 3:435 fluorinated derivatives of 5:451 Estragole 13:335;1:600 Estreogen 5:477,499,456;17:625-526 Estrogen 2-hydroxylases 5:449 Estrogen agonist/antagonist properties 26:210 secoisolariciresinol diglycoside 26:210 Estrogen hormones 9:411 Estrogen responsive kidney 5:447 Estrogenic activity 21:759;23:353 of coumarin 23:335,356,357, 353,368,376,393,550,553; 26:760 Estrogen-like activity 28:227 of phenols from moraceous plants 28:227 of Glycyrrhiza species 28:227 Estrogen-receptor antagonists 25:797 Estrone 4:501,502 asymmetric synthesis of 4:501,502 synthesis of 3:435 (-)-Estrone 4:675 (+)-Estrone 7:6 Et 722 25:826 Et 743 N 12oxide 25:825,827 Et's 25:595,581,592,826 Eteromorpha prolifera 25:691 Ethambutol 2:424,20:714 1,2-Ethanedithiol 11:357
311
Ethanoflurene 6:175 Ethanol 25:966 LTP-blocking effect of 25:966 [3H]-Ethanolamine 25:342 Ethanolamine 5:299 Ethanophenanthrene 6:173,174 5 5,10[3-Ethanophenanthridine nucleus 4:4 S,S'-l,2-Ethendiyl O,O'-diisobutyl 25:898 Etherification 4:718-720 Ethionamide 2:424 Ethisolide 3:261,19:485 Ethnoarcheological studies 13:630 Ethnomedical uses 23:652 of celastraceae 23:652 Ethnopharmacology 13:640 3-Ethoxcarbonyl-2-benzylideneproanoic acid 22:295 3-[cz-Ethoxy(ct-methyl-thio)]methyl-2thionopyrolidine 26:1083 5c~-Ethoxy-4,5-dihydrojabarosalactone B 20:223 a-Ethoxyacrylonitrile 30:449 photolysis of 30:449 3-Ethoxycarbonyl pyrrolidinone 13:131,132 2-(Ethoxycarbonyl)-tryptamine 19:89 19-Ethoxycarbonyl- 19-demethylvincadifformine 19:112,115 Ethoxycarbonylation 6:541 MIN-([3-Ethoxycarbonylethyl)-5oxopyrrolidine-2-carboxylate 12:308 Ethoxycarbonylmethylene (triphenyl) phosphorane 12:315;21:416 (3-Ethoxycarbonylpropyl) triphenylphosphoniumbromide 12:318 3-Ethoxycarbonylpyrrol- 2(5H)-ones 13:131,132 3-Ethoxy-coronaridine 5:126 bis-Ethoxyethyl olivetol 19:225 13-Ethoxylabda-8(17), 11,14-trien- 19oic acid N-(methyl)phthalamide 29:101 activity in EBV bioassay system 29:101 [3-Ethoxypropiophenone 14:648
1-Ethoxyvinyl lithium 30:458 reaction with 30:458 ozonolysis of 30:458 Ethoxyvinyllithium 30:458 as reagents 30:458 Ethyl (1R,2S)-5,5-ethyienedioxy-2hydroxycyclohexane- 1-carboxylate 6:552,553 Ethyl (2E,4E)- 12-hydroxy-2,4dodecadienoate 10:152 Ethyl (S)-lactate 12:161 Ethyl 1,6-dithiogentiobioside 8:341 synthesis of 8:341 Ethyl 2-(bromomethyl)-acrylate 30:451 nucleophilic addition of 30:451 Ethyl 2-[ 1-(2-ethoxycarbonylmethyl) piperidinyl]-propanoate 12:284 Ethyl 2-diazoacetate 30:446 reaction with 30:446 Ethyl 2-methoxy-6-methyl benzoate 9:346,347 synthesis of 9:346,347 Ethyl 3-(S)-hydroxybutyrate 6:263 Ethyl 3-hydroxybutanoate 1:689, 690,707 (S)-Ethyl 3-hydroxybutyrate 4:439, 440,448,449,452,453,455,464 Ethyl 4-[ 1-(2-ethoxycarbonylpyrrolidinyl)] butyrate 12:293 Dieckmann condensation of 12:293 Ethyl 8'-apo-f3-caroten-8'-oate 20:606 Ethyl benzamalonate 9:224 Ethyl benzimidates 22:292 Ethyl catechol 25:925-927 Ethyl diazoacetate 14:402 Ethyl fructofuranoside 8:324,325 (S)-Ethyl lactate 8:133,136 Ethyl malonyl CoA 11:194 Ethyl phenylpropiolate (EPP) induced edema 25:46 (+)-Ethyl picolate 12:279 Ethyl sorbate 8:410,414,148,149 24-Ethyl thomasterol A 15:48 Ethyl ~-bromocrotonate 8:418,419 Ethyl ~-trifluoroacetoxy acrylate 30:450
312 radical conditions 30:450 reaction with 30:450 Ethyl [3-apo-8'-carotenate 20:756 Ethyl-2-(diethoxyphosphonyl) propinoate 20:595 24-Ethyl-24,28-methylene-cholesterol 9:36,37 24-Ethyl-26-hydroxysteroids 15:84 2-Ethyl-2-hydroxyindolizidine 12:284 2-Ethyl-2-propen- 1-ol 14:828 (2S,3S)-2-Ethyl-3,4-isopropylidenedioxy-propan-l-ol 30:39 from L-malic acid 30:39 role in (-)-pironetin synthesis 30:39 2-Ethyl-3-vinylcyclopentanone enolate 8:192,193 9-Ethyl-4-hydroxy-3-hydroxy-methyl1,7-dio xasp iro-[ 5.5 ]-undec ane 14:531 1-Ethyl-4-methylsulfone-fl-carboline 25:819 2-Ethyl-5-heptyl- 1-nitrosopyrrolidine 6:439,440 synthesis of 6:439,440 3-Ethyl-5-methylindolizidine 6:450 2-Ethyl-5-pentylpyrrolidine 6:437,444 7-Ethyl-7-hydroxyindolizidine 12:286 3-Ethyl-allohobartine 11:318,319 24-Ethylbrassinone 18:500 5 '-N- Ethylc arb oxamidoadeno sine 27:878 (24S)-24-Ethylcholest-5,22-dien-313-01 (stigmasterol) 9:447 (24R)-24-Ethylcholest- 5-en-3 [3-ol (sitosterol) 9:447 (+)-3-Ethylcompactin 11:371 O-Ethylcryptaustoline iodide 6:482 (-)-N-Ethylcytisine 15:525 from Echinosophora koreensis 15:525 Ethyldeoxynojirimycin 10:527,528 NEthylene biosynthesis 25:657 Ethylene diamine tetraacetic acid (EDTA) 21:540;30:844 Ethylenediamine tetraacetic acid 21:540 N-Ethylene-methylketone 21:265,266
3-Ethylidene- 1,3-dihydro-indol-2-one 9:236,237 24-Ethylidenecholesterol 20:234 4,6- O-Ethylidene-N-benzoyl-Dglucosamine 18:462 Ethyllithium 14:510 Ethylmalonic acid 13:76 Ethylmaltol 22:540,528 Ethylphenyl acetate 6:323 2-Ethylpropane-l,3 diols 13:88-93 2-Ethylpropanol 14:840,841 7-O-Ethylrosmanol (abietane diterpene) 29:575 effects on HIV- 1 protease 29:575 synthesis from carnosolic acid 29:575 Ethyltetradecatrienoate 23:191 q 5-Ethyltetramethylcyclopentadienyl-dig-thiocynato rhodium complexes 21:222 Ethylurethanes 6:427,428 Ethylvinyl ketone 6:19 Etlatol 25:787 EtN 12oxide 25:826 Etopophosphate 26:160 Etoposide 5:461,462,13:364,365,654, 20:458;21:136,160;26:160-163,171, 172,212,21 -~ cytotoxiclty of 26:213 use in combination therapy 26:171 Etoposide phosphatase 21:160 Etoposide phosphate 26:160 in lymphoid cancer 26:171 in myeloid leukemia 26:171 in refractory testicular cancer 26:171 m stomach cancer 26:171 m ovarian cancer 26:171 m brain cancer 26:171 m breast cancer 26:171 in pancreatic cancer 26:171 m small/non-small lung cancer 26:171 Etzionin 10:247 Etzionine 240 Eu (fod)3-mediated 4:121,122,143 [4+2] cycloaddition 4:121,
313 122,143 Diels-Alder reaction 4:121,122 Eu (fod)3-mediated [4+2] cycloaddition 4:121,122,143 Diels-Alder reaction 4:121,122 Eu (hfc)3 4:326 Eubacterium saburreum 4:195 Eucalbanin B 23:405 Eucalbanin C 23:405,414 Eucalyptol 13:337 Eucalyptus 27:755;29:589 Eucalptus citriodora 25:32 Eucalyptus alba 23:405,413 Eucalyptus amplifolia 24:234;29:111 Eucalyptus blakelyi 24:234;29:111 activity in EBV bioassay system 29:111 from Euglobal-BI-1 29:111 Eucalyptus calophylla 19:247 Eucalyptus camaldulensis 28:427 acaricidal activity of 28:427 Eucalyptus globulus 24:232;28:402 Eucalyptus grandis 24:234,240; 26:445;29:111 Eucalyptus grandis 29:111 activity in EBV bioassay system 29:111 activity in EBV, lung-2, skin-l, skin-3 bioassay systems 29:111 activity in lung-2 bioassay system 29:111 activity in skin-1 bioassay system 29:111 activity in skin-3 bioassay system 29:111 euglobals from 29:111 Eucalyptus haemastoma 26:696 Eucalyptus incrassata 24:234 Eucalyptus marinata 19:247 Eucalyptus polybractea 24:232 Eucalyptus robusta 23:405 Eucalyptus' smithii 24:232 Eucalyptus sp. 21:526,527;29:83 Eucalyptus spathulata 15:248 (+)-spathulenol from 15:248 Eucaryote signals-regulated protein kinase (PK's) 25:521,522 (2S)-Euchrenone 28:17 as aromatase inhibitor 28:17
Euchresta formosana 29:781 Euclabanins 23:407 Euclea natalensis 30:328 isodiospyrin from 30:328 Eucommia ulmoides 5:505,521525,530,544 ;20:613,647-648;26:235 (+)-pinoresinol diglucoside from 26:235 Eucommiol 7:441,442,472-474 Eucryphin 27:395 Eudesm-11-en-4-ols 14:451 from Amitermes excellens 14:451 from Artemisia schmidtiana 14:450 from Bothriochloa bladhi 14:450 from Bothriochloa glabra 14:450 from Bothriochloa intermedia 14:449 from Bothriochloa insculpta 14:450 from Carthamus lanatus 14:450 from Citrus paradisi swingle 14:450 from Cymbopogon flexuosus 14:450 from Euginia uniflora 14:450 from Geigeria burkei 14:450 from Humulus lupulus 14:450 fromMyrica gale 14:450 from Pisidium guajava 14:450 from Podocarpus dacrydioides 14:450 from Riccardia jackii 14:450 from secretion of termite soldier 14:451 from Senecio amplexicaulus 14:450 from Subulitermes bailey 14:451 from Subulitermes oculatissimus 14:451 from Subulitermes parvellus sp. A+B 14:451 from Velocitermes velox 14:451 7-epi-Eudesm-4( 15)-ene- 1[3,6~-diol 21:584;23:635 Eudesmaafraglaucolide 7:232 Eudesman-12,6-olides 7:212,231-233
314
Eudesmane alcohol 14:456-465 from (-)-c~-santonin 14:456-465 synthesis of 14:456-465 Eudesmane sesquiterpenes 2:280 Eudesmanes 7:208,214,168,181,187; 25:848,849 activity in EBV bioassay system 29:87 1,2,6,8,15-pentaacetoxy-9benzoyloxy-4-hydroxy-dihydro[3-agarofuran as 29:88 1c~,2c~,15-triacetoxy-6[3,9[3difuroyloxy-4 ~-hydroxydihydro-[3-agarofuran as 29:88 1c~-acetoxy-2 ot-benzoyloxy6[3,9~3-difuroyloxy-4[3-dehydro13-agarofuran as 29:87 1c~-acetoxy-6a,9[3-difuroyloxy2a-( 2-methylbutyroyloxy)-4 [3hydro xy-dihydro- [3-agarofuran as 29:88 1c~-acetoxy-6~3,913-difuroyloxy2a,4[3-dihydroxy-dihydro-[3agarofuran as 29:87 1c~-acetoxy-6[3,913-difuroyloxy2c~-propyonyloxy-4 [3-hydroxydihydro-[3-agarofuran as 29:88 eumaytenol as 29:88 euonymine as 29:88 from Wieland-Miescher ketone 6:18,19 synthesis of 6:18,19 2,3-seco-Eudesmanes 7:216 4,5-seco-Eudesmanolide 7:215 6fl-Eudesmanolides 24:72,73 Eudesmanolides 6:18,19;24:56,806 from Wieland-Miescher ketone 6:18,19 synthesis of 6:18 Eudesmin 24:755;26:268 synthesis of 24:755 (-)-Eudesmin 26:200 (+)-ot-Eudesmol 14:406-413 synthesis of 14:406-413 (+)-13-Eudesmol 14:490;21:584 synthesis of 1:632;14:490
via asymmetric cyclopropanation 14:490 [3-Eudesmol 15:243,244;23:811 neointermedeol from 14:453,454 ozonolysis of 14:453,454 ElO-epi-~[-udesmol 21:583,584 7-epi-cz-Eudesmol 21:583,584 ot-Eudesmol 21:583,584 lO-epi-~/-Eudesmol 23:811 [3-Eudesmol 21:583,584;29:87 activity in AM assay system 29:87 Eudesnols 21:583,584,585 Eudestomins 8:274 Eudistoidin E and F 25:818 Eudistoma 19:660 Eudistoma album 23:263 Eudistoma cf. rigida 10:247;28:635 iejimalide C from 28:635 iejimalide D from 28:635 Eudistoma divaceum 25:902 Eudistoma fragum 23:257 Eudistoma gilboverde 28:634 methyleudistomidin C from 28:634 Eudistoma glaucus 5:353;23:262,263; 25:758,817;28:634 eudistomidin C from 28:634 Eudistoma olivaceum 5:100,417,418, 246;21:260,321 ;25:816;28:633 [3-carboline alkaloids from 28:633 eudistomins from 21:260 N(10)-methyleudistomin E from 28:633 Eudistoma sp. 12:366,370;10:247; 25:820,834 ;28:637 desmethylvaracin from 28:637 Eudistoma taoelensis 21:260 N-demethyl staurosporine from 21:264 3-hydroxy staurosporine from 21:264 staurosporine from 21:254,264 Eudistomidin A 23:261 ;5:758 Eudistomidin B 25:759 Eudistomidin C 25:758 Eudistomidin D 25:758,759
315 Eudistomidin F 25:863 Eudistomin A 5:418;23:261 Eudistomin C 5:417,418;25:782 Eudistomin D 5:418;23:261 Eudistomin E 5:417,418;25:782 Eudistomin F 5:418 Eudistomin G 5:418;23:261 Eudistomin H 5:418;23:261 Eudistomin I 5:418;23:261 Eudistomin J 5:418;23:261 Eudistomin K 5:418;23:261 Eudistomin K sulfoxide 25:863 Eudistomin L 5:417-418 Eudistomin M 5:418;23:261 Eudistomin N 5:418;23:261 Eudistomin O 5:418;23:261 Eudistomin P 5:418;23:261 Eudistomin Q 5:418;23:261 Eudistomin R 5:418 Eudistomin S 5:418 Eudistomin sulphide 25:816,817 Eudistomin T 5:418 Eudistomins 23:233,262,268;25:782, 815,817 occurrance of 23:265 oxathiazepine ring of 23:265 Eudistomins A-Q, S,T 10:246,247 Eudistomins C,E,F and L 25:816,817 Eudistomins D,J,N and O 25:782 Eudistomins H&I 21:321 Eudynamis scolopacea 5:837 Eugenia 21:600;27:755 Eugenia caryophyllata 21:585 Eugenia uniflora 14:450;23:405 Eugeniflorin D1 23:405,410 Eugeniflorin D2 23:418 Eugenol 5:473,474;21:572,586,594, 595,600,602,613 ;25:126;28:403 acaricidal activity of 28:403 as bioactive monoterpenoid 28:426 Euglena gracilis 23:124;26:363;30:397 (1-3)-~-D-glucan from 30:397 Euglena viridis 6:150 Euglenophyta 27:735 Euglenopyceae 6:134,147,150,151 Euglobals 29:111 activity in EBV bioassay system 29:111
Euhypericum 30:610 hypericin from 30:609 Eukaryate signal transduction 25:512 components 25:512 inhibition of 25:512 Eukaryotes 22:57;23:14 Eukaryotic genes 4:268 Eukaryots 27:736 Eumelanins 26:1018 Eumenes fraternus 5:224,225,232,253 Eumycota 9:202 Eunicea 10:9 Eunicea fusca 21:276;29:690 Eunicea succinea 26:83 Eunicea taurneforti 20:492;25:690 Eunicella cavolinii 25:690 Eunicia succinea 10:7 Euniolide 10:7 Euodynrus fuscus 5:224,253 Euoniminol 18:747 Euonomynus 18:741 Euonymine 29:88 activity in EBV assay system 29:88 Euonyminol 23:663,674 (+)-Euonyminol 23:664 Euonymus 18:753 Euonymus alatus 23:655 Euonymus atropurpureus 23:655 Euonymus bungeanus 23:668 antifeedant sesquiterpenes from 23:668 insecticidal sesquiterpenes from 23:668 Euonymus europaeas 23:655,674 Euonymus fortunei 23:668 Euonymus tingens 30:668 tingenone from 30:668 Euonymus verrucosus 23:656 Eupafolin 7:226 Eupatilin 20:712 from Salvia limbata 20:712 from Salvia nemorosa 20:712 Eupatin 7:227 Eupatorenone 5:28-30;7:275,276 Eupatorium adenophorum 5:28 Eupatorium articulatum 22:353 Eupatorium fortunei 24:273 Eupatorium gracile 29:573
316
Eupatorium maculatum 20:145 Eupatorium quadrangulare 24:103 Eupatorium trapezoideum 15:247 Eupatorsum inulaefolium 22:349 5,6,3 '-trihydroxy-7,4 '- dimethyoxyflavone pedalitin from 22:349 Eupatrin 30:726,727 structure of 30:726 Eupentactafraudatrix 7:275,276; 21:314;28:598 from calcigeroside B 28:598 from calcigeroside CI 28:598 from calcigeroside DI 28:598 from cucumarioside G2 28:598 Euphane 25:50 Euphanes (tirucallanes) 9:267,297, 302,307 (-)-Euphococcine 16:481 synthesis of 16:481 Euphol 25:61 Euphorabia characias 26:1263,1277 Euphorbia 12:233,234;25:242 Euphorbia acaulis 9:265,267,288 Euphorbia brachypoda 28:400 Euphorbia caudicifolia 9:265 Euphorbiafidjiana 9:265-292;15:385 Euphorbiafisheriana 22:520 Euphorbia genera 27:830 Euphorbia helioscopia 9:265;23:406 Euphorbia hirta L. 22:520;23:405 for convulsions 22:520 Euphorbiajolkinii 9:265 Euphorbia lagascae 9:391 Euphorbia laterifolia 2:262 Euphorbia lathyris 24:273 Euphorbia maculata 23:406 Euphorbia maddeni 25:594 Euphorbia milii 5:678 Euphorbia myikae 22:520 Euphorbia nerifolia 7:152-15.4 Euphorbia nyikae Pax. 22:520 for epilepsy 22:520 Euphorbia obovalifolia"s latex 28:400 acaricidal properties of 28:400 Euphorbia pallasii 9:265,288 Euphorbia pekinensis 29:579 Euphorbia poisonii 2:261 Euphorbia prostrata 23:406
Euphorbia quiquecostata 29:103 Euphorbia resinifera 30:193 resiniferatoxin from 30:193
Euphorbia sp. 9:265,267,20:19 Euphorbia tirucalli L. 22:520;23:406 Euphorbia triaculeata 9:265 Euphorbia watanabei 23:406 Euphorbiaceae 23:405;25:242,243,245 Euphorbin A 23:405,413 Euphorbin C 23:405 Euphorblaceaephyllantus 22:720 Euphoria 21:101 Euplaxaura erecta 14:315 Eupomatenoid-5 26:202 Eupomatenoid-6 26:232 Eupomatia laurina 24:790 Euponera sp. 5:224 Euretaster insignis "/:304,94,45 Eurobustin A 23:405 Eurobustin B 23:405 Euroglyphus maynei 28:417 Europhthalma 6:422-434 Europine 26:874 Europine N-oxide 1:275 Europium sp. 5:325 Eurotium chevalieri 26:1091,1093, 1094,1097-1099 Eurycoma longifolia 7:393;23:300; 24:282 Eurycomalactone 7:393;11:71 Eurycomanol 7:393 Eurycomanone 7:393 (-)-Euryfuran 4:404 from Hysselodoris califomiensis 4:404 from Hysselodorisporterea 4:404 (+)-Euryfuran 6:28 from (+)-confertifoline 6:28 from (+)-manool 6:28 from Dysidia herbacea 4:404 from Euryspongia species 4:404; 6:20 from Hypselodoris califorensis 6:20 from Hypselodorisporterae 6:20 from manool 4:422-424 from trimethyl decalone 6:20
317 synthesis of 6:20,28,116,403, 422-424 Euryspongia 28:667 15-acetylthioxyfurodysin from 28:667 Euryspongia arenaria 25:703 Euryspongia deliculata 25:694 Euryspongia sp. 4:404 Euscaphic acid 29:575 effects on HIV- 1 protease 29:575 Eustigmatophyceae 6:134 Euterpe spp. 22:355 Euthyneura 21:3 Euthyroideones A-C 25:862,863 Euthyroideones 25:862 Euthyroides episcopalis 25:862;28:621 euthyroideones from 28:621 Eutreptiellanone 6:150,151,153 Eutypa lata 21:204 Euxanmodin A 20:277 Euxlophorine A 1:127 Evan's alkylation 19:62 Evan's reduction 18:253 Evans aldol methodology 16:483 Evans aldol-condensation reaction 30:13,33 Evans asymmetric alkylation 1:455,456, 469,604 Evans asymmetric induction procedure 14:534 Evan's asymmetric strategy 12:435,436 Evan's chiral auxiliaries 12:435-438 Evans chiral oxazolidine 26:1226 Evans oxazolidinone-mediated syn-aldol condensations 30:44 Evan's rearrangement 16:296 Evan's-Cope reaction 12:193 Evan's-Cope ring expansion 12:192 Evasoteria troschelii 25:813 Evening primrose oil 13:658,659 Evernia prunastri 5:310-312,322 L-Evernitrose 19:118 Evodia rutaecarpa 26:487 Evodiopanax innovans 29:573 Evolution 18:677-728 Evolutionary aspects 9:591-609 of vitamin B ~2biosynthesis 9:591-609
Evolutionary molecular modeling 21:3,5,104,107 of alkaloids 21:102 Evonine 23:678 Evoninic acid 23:674 Evoninol 18:747;23:674 Evuncifer ether 14:452,463 from Amitermes evuncifer 14:452,463 from Amitermes excellens 14:452 from Amitermes messinae 14:452 Exact vs. nominal mass 2:44 Exaltolide 19:118 Excelsin 7:398 Excisanin A 15:171;29:101 activity in EBV bioassay system 29:102 activity in NFkB bioassay system 29:101 activity in NO bioassay system 29:101 constiutents activity in skin-1 bioassay system 29:102 from Rabdosia excisa 15:171 from Rabdosia inflexa 15:172 from Rabdosia macrocalyx var. jiuhua 15:173 from Rabdosia serra 15:174 Excisanin B 15:171 from Rabdosia excisa 15:171 from Rabdosia macrocalyx var. jiuhua 15:173 Excisanin C 15:115,121,129,171 Exciton interaction 2:164 Exciton-chirality method 18:748 Excoecaria agallocha 7:176178,180,183,195 ;22:520;29:102 activity in EBV/skin-1 bioassay systems 29:102 (13R,14R)-ent-8a,13;14,15diepoxy- 13-epi-labdan-3p-ol from 29:102 ent- 13-epi-8,13-epoxy-2,3secolabd- 14-ene-2,3- dioic acid 3-methyl ester from 29:102 ent- 13-epi-8,13-epoxy-2-hydoxylabd- 1-en-3-one from 29:102
318
ent- 13-epi-8,13-epoxy-2-oxa-3oxolabd- 14-ene- 1R-carboxylic acid methyl from 29:102 excoecarin A from 29:102 excoecarin B from 29:102 excoecarin F dimethyl ester from 29:102 excoecarin H methyl ester from 29:102 excoecarin from 29:102 ent- 16-hydroxy-3-oxo- 13-epimanoyloxide from 29:102 11 [3-hydroxy-ribenone from 29:102 ent- 13-epi-manoyloxide from 29:102 for epilepsy 22:520 Excoecaria kawakamii 23:406 Excoecarianin A 23:406 Excoecarianin B 23:406 Excoecarin D 29:100 activity in EBV assay system 29:100 Excoecarin E 29:100 activity in EBV assay system 29:100 Excoecarin M dimethyl ester 29:101 activity in EBV bioassay system 29:101 Excoecarin-N-dimethyl ester 29:100 activity in EBV assay system 29:100 Exelsine 23:710 Exencephalic hamster fetuses 23:570 Exencephaly 7:20,21 Exidonin (rabdosin B) 15:143,152, 160,172,173 from Rabdosia henryi 15:172 from Rabdosiajaponica 15:172 from Rabdosia longituba 15:173 Exifone 25:349,350,351 2,3,4,3',4',5'-hexahydroxybenzophenone 25:349 Exiguaflavanone 26:801,803 Exo addition 8:160,161 Exo orientation 14:753 Exo-enamine system 30:443
(+)-C-2'-ara-Exo-enol tautomer 14:101 fluoroguanosine 10:609 antiviral activity of 10:609 Exoerythrocytic cycle 26:781 Exogenous compounds 22:4 Exogenous peptide signals 25:393 exo-glycal 30:458 conversion to labile epoxide 30:458 Exons 13:290 3'-Exonuclease 13:288,291 Exonucleases 13:290,291 Exophiala dermatitidis 28:476 Exophilin A 25:723 Exophiola pisciphila 25:723 f. sp. gladioli 25:307 f. sp. melonis 25:307,411 f. sp. niveum 25:307 f. sp. tuberosi 25:307 sp. lycopersici 25:295,299,307, 312-314,316,318 Exopolyphosphatase 25:718 Exoproteases 25:331 5-exo-Trig aryl radical-alkene cyclization 3:327,328 Exo-a-galactosidase 25:438 Exo- a-mannosidase 25:436 Exo-fl-l,3-glucanase 10:526 Exo-fl-galactosidase 25:438 Expectorant 17:451 Expectorant activity 21:633;28:200 of genus Morus 28:200 Extracellular LRR domains 25:401 Extracellular polysaccharides 30:421 Extracellular promastigote 26:790 toxicity assays for 26:790 Extracellular signal regulated kinases 25:526 Extrachromosomal HBV DNA 20:541,544 Extraction 9:449,450;21:502-505 of essential oil 21:573-577 Extracts of Geranii 27:414 effects on serum total cholesterol 27:414 Eye fatigue 30:64 use of carp in 30:64 Ezoalantonin 7:233
319 Ezomontanin 7:235 Ezomycin A-1 4:246,247 Ezomycin A-2 4:245,247 Ezomycins 1:422,431 synthesis of 1:422,431 for preparation of phytotherapeutic drugs 30:750 z-Facial selection 12:419-422 in methoxybromination 12:419-422 in methoxyselenylation 12:421, 422 reversed 12:419-422 Facial selectivity 10:36 F-Actin 22:33 Factor-a-dependent inflammatory liver injury 25:459 Fagaceae 23:403 Fagara macrophylla 7:427;27:168 Fagara sp. 27:164 Fagara xanthoxyloides Lam. 27:159 Fagaridine 14:783 ),-Fagarine 20:539,540 a-Fagarine 25:539 Fagarine I 21:68 Fagaronine 3:430;14:769,776,777; 13:656,769,770,775-777;22:27 Fagaropsis angolensis 27:164 Faglis sylvatica 25:662 Fagomine 7:15,10:543,544;22:184 Fagopyrum esculentum 21:527;29:608 Fagraea racemosa 26:268 (+)-epiresinol from 26:268 (+)-isolariciresinol from 26:268 (+)-pinresinol from 26:268 Falcaria sp. 27:686 Falcaria vulgaris 27:422 Falcarindiol 7:415;25:471,476 Falcipain 25:331 inhibition of 25:331 Fallacinol 22:609,610 Fallopiajaponica 22:608 Fallopia sachalinenesis 22:608 Falvanones 23:742 Famciclovir 20:534 Fames spp. 24:172 a-Famesene 25:546
fl-Famesene 25:546 Famotidine 25:612 FAMSO 6:311-313 aldehyde synthesis by 6:311-313 alkylation of 6:313,315,316 dianion of 6:323-325 methyl methylthiomethyl sulfoxide in 6:309-325 organic synthesis by 6:311-323 oxidation of 6:311 preparation of 6:309-311 Fana zava 23:659 Fangchinoline (bisbenzylisoquinoline) 29:578 effects on ACE 29:578 Faradiol (taraxast-20-ene-3 p, 16[~-diol) 25:57,58,62,63 ;29:586 effects on CHY 29:586 Faradiol 3-O-myristate (taraxast-20-ene313,16f3-diol 3-O-myristate) 25:58; 29:586 effects on CHY 29:586 Farensyl pyrophosphate 25:237 (+)-Fargesin 26:201,267 Fargesin 26:241 as PAF-induced inhibitor 26:241 Fargesone A-C 26:233 Farmosan gorgonian 25:690 Farnesal 8:19;22:379 E isomer 8:19 oxidation with SeO4/t-BuOOH 8:19 oxidation with BaMnO4 8:19 reaction with ethyl 1-diethylphosphono-2-methylbutanoate 8:18,19 reduction with LiA1H4 8:19 Z isomer 8:19 Farnesane 23:546 Farnesane sesquiterpenes 17:155 [3-Farnesene 7:100,101,103,121123;27:586 Farnesoic acid 22:379 E,E-Farnesol 1:656 Farnesol 7:108,125,8:222,20:88; 21:589,595;22:401 ;25:125,162,165168;26:331,332;27:586 trans-trans-Farnesol 23:802
320
(E,E)-Famesol derivatives 1:657 cis, trans-Famesol pyrophospate 5:730,731 (Z,E)-Famesols 8:75 (E,E)-Famesols 8:75,77 (E,E)-Famesyl acetate 1:663 Famesyl acetate 8:197,198 cis-Famesyl diphosphate 21:230 Famesyl diphosphate 7:324;22:253 Famesyl isothicyanate 21:346;25:854 Famesyl pyrophosphate 6:247,248; 22:253,635,636,637 Famesylation 24:409-410 of protein 24:409-410 Famesyl-protein transferase 24:403-464 as natural product inhibitor 24:403-464 for cancer chemotherapy 24:403-464 (E,E)-Famesylsulfone 1:657 Famesyltransferase 22:257 Famochrol 7:224 Fascaplysin 5:411,412 Fascaplysinopsis sp. 5:411 Fasciospongia cavernosa 25:688, 697,703 Fasciospongia rimosa 19:568;25:874 Fasicularin 25:860 Fast Atom Bombardment (FAB) 24:138 of saponins 24:138 Fast oligonucleotide deprotection (FOD) 13:266 Fat 27:402 hydrolysis of 27:402 Fat cell 27:393 biological activity of 27:393 Fatty acid 11:191;21:187,196 antileukemic activity of 7:24 biosynthesis of 11:191 by condensation of malonyl unit 11:191 metabolites derived from 21:187,196 oxidative degradation of 13:303306 stereochemical course of 11:191 Fatty acid components 28:565 of carp oil 28:565 of tuna oil 28:565
Fatty acid synthase type-I 25:500,501 Favorskii reaction 6:335 Favorskii rearrangement 8:225 ;10:410; 16:242;20:69,70 (+)-Faxiresinol- 1-[3-D-glucoside 5:524, 538,542,543 FDP aldolase 14:176 Fe(IlI) protoporphyrin 25:332 FeCla-induced epilepsy 22:509 Feist's acid 10:618 Felbamate 22:508 Felidae 7:7 Felikiol 5:736 Feline leukemia virus (FeLV) 21:646 anti-Felkin product 30:17 Felkin-AHN model 11:234,440,474, 643 ;12:21 ;19:474 Felkin-ANH conformation 3:255,134 Felkin-ANH transition state 1:402,406, 423 Felkin-Nguyen (Anh) 8:213 a-Fenchol 25:154 (+)-Fenchone 16:268 from Eremophila caerulea 15:227 Fenchone 4:649;20:16;21:599 Fenestrene (lauren-l-ene) 3:117-124 synthesis of 3:117-124 Fenfangjine A (bisbenzylisoquinoline) 29:578 effects on ACE 29:578 Fenoprofen 6:323 Fentanyl 30:198 Fenton process 25:931 Fenton reaction 22:316,327;25:330,634, 644;26:975,995 Fercolide 5:723,724 Fercomin 5:723,724,728 Fernenol 7:218 fromArtemisia vulgaris 7:218 Feronia elephatum 21:600 Ferredoxin-NAD oxidoreductase 20:835 Ferrichrome 9:551,555 Ferrier reaction 10:347,419,433-437, 510 Ferrier rearrangement 13:191,200,201, 203,210
321
Ferrier-type reactions 3:212,213 elimination-addition by 3:212, 213 filifolone by 3:40 synthesis of 3:40 Ferrihemoglobin 26:985,986,991 -mediated oxidation 26:991 Ferri-pyoverdins 9:553 Ferritin 22:327 Ferroprotoporphyrin IX 20:518 Ferrous sulphate reduction 4:422,432 Ferruginol 2:402,403;14:668,670, 674,689,690 from Salvia candidissima 20:660 from Salvia limbata 20:673 from Salvia montbretii 20:666 from Salvia napifolia 20:670 Ferruginyl 12-methyl ether 20:665,666 from Salvia pomifera 20:665,666 Ferry linyoglobin 25:934 Fertility regulation 13:658 Fertility-regulating agent 13:658 Ferugin 5:725,726 Ferula akitschkensis 5:723 Ferula alliacea 22:521 for epilepsy,hysteria and infantile convulsions 22:521 Ferula arrigonii 24:81 Ferula communis subsp, communis 5:723; 8:57 Ferula elaeochytris 5:723 Ferula foetida 22:521 for convulsions 22:521 Ferula galbaniflua 19:157-158;22:521 for epilepsy 22:521 Ferulajaeschkeana 5:725 Ferulakaratavika 1:660 Ferula lancerottensis 5:725,727 Ferula lapidosa 5:723 Ferula linkii 5:725,734;29:91 Ferula pallida 5:723 Ferula rubicaulis 19:158 Ferula sp. 5:721,732 Ferula tenuisecta 5:723 Ferula tingitana 5:723 Ferulamide derivative 22:490 Ferulate 5-hydroxylase 5:468,469 ferulic (3-methoxy-4-hydroxy) as 28:261
p-coumaric (4-hydroxy) acid as 28:261 sinapic (3,5-dimethoxy-4hydroxy) as 28:261 Ferulic acid 5:469,470,474,475,479, 495 ;21:618 ;23:537,551,744,745; 25:56,57,653,662,665,671,920; 27:746;28:262 in citrus juices 28:262 in cereal brans 28:262 in coffee 28:262 in sugar beet fibre 28:262 E-Ferulic acid 5:472 Z-Ferulic acid 5:472 Ferulic acid dimers 27:757 structure of 27:757 Ferulic acid ester 25:655,665 Ferulic and p-coumaric acid 25:920 Ferulidin acetate 7:236 Feruloyl CoA 25:653 Feruloyl malate 23:761 Feruloyl quinic acid 23:745 3-O-Femloyl-4-O-caffeoylquinic acid 25:920 Feruloylglycine 25:923 3-O-Feruloylquinic acid 25:920 Feruone 5:724,725 Ferutidin 5:622,623 Ferutinin 5:722,723,731,732 Festigiolide 5:728 (+)-Festuclavine 18:386 Fetizon oxidation 4:340,343,370 Fetizon's intermediate 12:196,198 Fetizon's photochemical route 12:195 Fetizon's reagent 1:349,366,508,570; 18:28 Fever 22:532 Sida cordifolia L. for 22:532 Feverfew 13:660 F-gitonin 25:308 F-I 30:826 as isozyme 30:826 F-I-0 30:826 as isozyme 30:826 F-I-2 30:826 as isozyme 30:826 FIavonol glycoside 22:644
322
Fibrinogen 30:834,838 conversion of 30:834 fibrin from 30:834 Fibrinolysis rate 30:841 effect of G-90 30:841 Fibrinolytic activity 21:670;30:826,827 from earthworm Eisenia fetida 30:826 Fibrinolytic agent 30:839 in disease prevention 30:839 in treatment of clotting disease 30:839 in acute myocardial infarction 30:839 in cerebral thrombus 30:839 Fibrinolytic effect 30:840 of lyophilized powder 30:840 Fibrinolytic efficacy 30:839 in vitro 30:839 Fibrinolytic enzyme 30:825,827,839 from Lumbricus rubellus 30.'825 from Lumbricus bimastus 30:827 in thrombosis treatment 30:839 recombinant prourokinase (proUK) as 30:839 recombinant tissue-type plasminogen activator as 30:839 staphylokinase as 30:839 streptokinase (SK) as 30:839 urokinase (UK) 30:839 Fibrinolytic mechanism 30:837 Fibrinolytic medicine 30:842 activity of 30:842 half life of 30:842 immunogencitity of 30:842 properties of 30:842 re-occlusion rate of 30:842 Fibroblast growth factor 30:56 angiogenesis by 30:56 Ficin flavonoids 26:744 Ficisterol 9:40 biosynthesis of 9:40 Ficus brachypoda's latex 28:400 acaricidal properties of 28:400 Ficus capensis 22:521 for convulsions 22:521 Ficus costata 2:231 Ficus diversiformis 2:231
Ficus elastica 8:66 Ficus fergusoni 2:231 Ficus microcarpa 29:788 Ficus pyrifolia 20:522 Field desorption (FD) 2:46-48,632,645, 467,487;24:138 of saponins 24:138 Field-collected samples 29:254 cytotoxic activity of 29:256 Fieser's solution 19:653 Figepitope 25:394,395 F-I-I 30:826 as isozyme 30:826 F-II 30:830,836,838 C-terminal region of 30:838 inhibition of 30:836 N-terminal region of 30:838 secondary structure of 30:830 F-II cleavage 30:838 of human plasminogen 30:838 F-Ill 30:826 as isozyme 30:826 F-III- 1 30:826,828,830,833,836 as isozyme 30:826 caseinolytic activity of 30:833 inhibition by Soybean trypsin inhibitors (SBTI) 30:836 inhibition of 30:836 N-terminal sequences of 30:828 secondary structures of 30:830 F-III-l(2) 30:831 homologous sequences of 30:831 F-III-2 30:826,828,830,833 as isozymes 30:826 fibrinolytic activity of 30:833 N-terminal sequences of 30:828 secondary structures of 30:830 Fijian sample 28:337 varacin from 28:637 Filamentous fungi 9:203 Filifolide A 7:208 from Artemisiafilifolia 7:208 Filifolone 7:208 fromArtemisia filifolia 7:208 Filipendula ulmaria 23:397 Filipin 24:548 antiviral microbial-derived compound 24:548
323
Filospadin flavonoids 26:744 Filter-sterilized pectinase 25:485 Finavarrene 21:305 Finitin 7:212,232 Finkelstein substitution 6:310 Fire ant 1:682;6:422 First-order kinetics 30:786 Fischer carbene complexes 1:505,506 Fischer indole reaction 14:845 Fischer indole synthesis 1:79,144,152, 284;11:285,492 Fischer indolization 1:15,51,60 Fischer projection 11:422,423 Fischerella 26:366 Fischerella ambigua 23:342; 25:792;26:364 Fischerella major 25:802 Fischerella muscicola 25:802; 26:364,366 Fischerellin 26:370,374 Fischerellin A 26:364,368 Fischer-Helferich procedure 4:222 Fischer-Kiliani synthesis 4:157-159, 175,179 Fisetin (3,7,3',4'-tetrahydroxyflavone) 22:322,326;25:541,543,544;26:757, 758;29:579 effects on ACE 29:579 Fisetin 29:572,581,582,585 effects on HIV- 1 protease 29:572 effects on LELA 29:585 effects on MMP 29:582 effects on NEP 29:581 Fish oils 28:566 anti-tumor activity of 28:566 Fisher-Irwin test 9:386 Fits 22:518,524 Cuscuta europea L. for 22:518 Jatropha curcas L. for 22:524 Fits in children 22:531 Ruta graveolens L. for 22:531 Fitzsimmon cycloaddition 11:447 FK 22:257,258,506 FK 508 25:464 as immunosuppressive drug 25:464 FK-506 8:273 FKBP12 22:258
FL3-27 gene proprotein 29:592 effects on cysteine protease 29:592 Flabellin 25:394;27:578 Flagellin protein 25:394 Flagpole type interaction 14:736 Flammulina velutipes 5:289 Flash pyrolysis 1:250 Flash vacuum pyrolysis 3:27,588 Flash vacuum thermolysis 1:337 Flatulence 5:754 Flavan-3-diols (leucocyanidins) 22:420 Flavan-3-ols 22:420;23:742,749, 772;28:273 (+)-catechin 28:273 epicatechin 28:273 Flavanolols (dihydroflavonols) 22:421 Flavanols 22:420,421 ;28:272 structure of 28:272 Flavanones 17:143-144,580;22:312, 420,432;28:270 eriodictyol 28:270 hesperetin 28:270 hesperidin 28:270 in chick peas 28:271 m citrus fruits 28:271 m cumin 28:271 in hawthorn berry 28:271 in licorice 28:271 in peppermint 28:271 in rowanberry 28:271 isosalipurpurin (chalcone) as 28:271 phloretin (dihydrochalcone) as 28:271 Flavans 7:192;22:420, Flavin adenine dinucleotide 26:917,918, 951 Flavin mononucleotide 26:917,918,951 Flavobacter dehydrogenans 9:417,418 Flavobacterium 4:432 Flavobacterium sp. 7:330,336,341345,347-351,358,360,363 ;25:868 Flavocarpine 1:124,135,153,156 Flavocristamides A and B 25:868,869, 903 Flavoglaucin 9:313 Flavokawin B 23:808 Flavologlycan polymer 7:193
324
3,5,7,4'-Flavone 27:844 Flavone 4:377,12,13,622,624,634,737639,643,651,653,252 Flavone glycosides 30:235 acidic hydrolysis of 30:235 sugar moieties of 30:235 Flavones 23:742,772;28:266,267, 285;30:236,285 absorption of 28:285 apigenin 28:267 as plant tissue color 28:267 chrysin 28:267 diosmetin 28:267 isoorientin 28:267 isovitexin 28:267 lutcolin 28:267 orientin 28:267 pinocembrin 28:267 ~3C-NMR spectral data of 30:285 UV spectra of 30:236 vitexin 28:267 Flavonoid aglycones 21:552 Flavonoid C-glycosides 5:643;10:362 Flavonoid disulphates 5:655 Flavonoid glucuronide 5:643 Flavonoid glycosides 5:632,633, 641,645,649,656,658,664,665; 23:487,521 Flavonoid p-coumaroyl glycosides 30:274 genkwanin from 30:274 Flavonoid sulphate 5:655,663,664 Flavonoid-6,7-disulphate 5:648 Flavonoidal alkaloids 21:130 synthesis of 21:130 Flavonoids 4:367,5:3,12,467,510,511, 621-624,627,630,632,637,641,642, 645,649-652,659-662,666,757,756; 7:202,206,208,220,226-228,411-413, 427;9:390,15:30;17:341 ;20:283,709; 21:457,459;22:419,307,311,344;23:3 42,536,553,638,747,802;24:215,218228,799;25:607 ;27:425,504 ;30:56, 70,233,234,238,241,272-277,284285,619,628,629,724,725,562 activity of 27:504 against Staphyllococcus aureus 30:629 anti-thrombic actions of 30:70
as glycosides 30:724 biogenetically formation of 30:233 biological activity of 27:425 effect on prostaglandin E2dependent cytoprotection 25:607 from luteolin 30:619 from miscellaneous genera 30:272-277 1H-NMR spectra of 30:238,284 identification of 30:234,235 inhibitory activity of 30:629 isolation of 30:233-236,619 methoxyl protons of 30:241 purification of 30:233,234 of citrus fruits 23:747 wound-healing effect of 30:628 Flavonols 5:192,622,624,626,628,634, 637;17:117,139-141;22:312;23:553, 742,772;26:744 ;28:264,265,284; 30:616 amentoflavone 30:616 as sulfated glycolipid 28:718 biflavones 13-biapigenin 30:616 eicosane- 1,16-disulfate from 28:718 Forbesin 28:718 from onions 28:284 glycoside derivatives 30:616 glycosides of 28:284 hyperoside 30:616 in kaempferol 28:265 in plant foods 28:265 in quercetin 28:265 isoquercitin 30:616 quercitin 30:616 rutin 30:616 structure of 28:264 Flavonol 3-methyl ethers 7:411,412 Flavonol glycosides 23:758 Flavonol methyl ethers 7:411,412 Flavonol myricetin 770 Flavonol quercetin 26:753 Flavonone 5:643;26:743,744;27:893 Flavopereirine 1:124,129-136,141143,145,147,149,153,155,156
325
Flavopiridol 21:153 anticancer activity of 21:135,136 clinical usage of 21:138 Flavopiridol-induced cytotoxicity 21:136 Flavoprotein 22:12 Flavoprotein oxidase 22:5 Flavors 13:322-345 analysis of 13:322-345 biogeneration of 13:295-345 legislation of 13:337-340 Flavour materials 27:374 from Labiatae 27:374 Flavoxanthin 20:727 Flavylium salts 22:420 Flemingia congesta 29:775 Flemingia rhodocarpa 29:775 Flemingia strobilifera 22:521 for epilepsy, hysteria and nocturnal epilepsy 22:521 Flemingia wallichi 29:775 Flexibacter elegans 9:323 Flexibilene 8:16,17 synthesis of 8:16,17 Flexicaulin A 15:117,124,131,171 Flexirubin 9:314,323,328,329,368 Flexuosol A 26:569 Florisil column chromatography 14:661 Flourinated erythromycin 25:780 5-Flourouracil (5FU)-induced lethality 25:447,448 protective effect 25:447,448 Flouro-[3-1actone 16:727-744 Flow cytometry analysis 24:220-239 Flu 30:691 Maytenus amazonica for 30:691 Fluconazole 22:60,248 Flucytosine Flueggea virosa 22:521 for epilepsy 22:521 Fluometuron 25:669 Fluorene 6:173 Fluorenone 6:176-181;26:655 N(2-Fluorenyl) guanidine 8:382,383 Fluorenylguanidine 8:382 N-9-Fluorenylmethyloxycarbonyl (fmoc) 4:289 Fluorescence indicator fura-2 18:856 Fluorescence inducing reagents 9:453
Fluorescence spectrometry 26:378 Fluorescent antibodies 30:841 Fluoresein 5'-isothiocynate (FITC) 25:446 4-Fluorestradiol 5:447,448,451-454 8'-Fluorinated abscisic acid analogs 27:346 Fluorinated analogues 9:517,518 Fluorinated compounds 29:343 4-fluorothreonine as 29:343 fluoroacetate as 29:343 Fluorinated probes 27:333 activity of 27:333 Fluorination 13:81-83 of alkylmalonate 13:83 of chiral half-esters 13:81 of monalkyl malonic acid 13:81 with 1-fluoro-2,4,6-trimethylp yridinum- trifluoro me thane sulfonate 13:82 4-Fluoro-2-hydroxyestradiol 5:454 4-Fluoro-2-methoxyestradiol-3-methyl ether 5:453 5-Fluoro-6-fluoro-substituted alkaloids 29:344 as synthetic fluorinated compounds 29:344 8'-Fluoro-abscisic acid 27:335 3'-Fluoro-abscisic acid 27:349 16-Fluoroaphidicolin 22:235 Fluorocarbon extraction 21:577 C-Fluorocurarine 1:36 Fluorocurarine 1:41,46-48 synthesis of 1:41,46-48 5-Fluorocytosine 22:60 8-Fluoroerythromycin A (flurithromycin) 13:166 synthesis of 13:166 3-Fluoroestr- 1,3,5 (10)-trien- 17~-ol 5:449 2-Fluoroestradiol 5:447-456 Fluoroestrogen 5:451,453,454 Fluoroglycosides 10:368-370 6-Fluoroheptulosonic analogues 30:473 ct-Fluoroketone 5:449 13-Fluoroketone 5:4502 ct-Fluoromethylamino acids 10:147,148
326 5-Fluoro-Nb-acetyltryptamine 29:344 as synthetic fluorinated compounds 29:344 25-Fluoroponasterone A 29:19 as synthetic ecdysteroid analogues 29:19 Fluoropyrimidines 22:58,63 Fluorosampangine 23:64Fluorosugars 10:368-370 Fluorosulfonic acid 30:215 1-Fluorotetrahydrocannabinol 30:196 Fluorotryptamines 29:344 as synthetic fluorinated compounds 29:344 5-Fluorouracil (5-FU) 21:136;22:60; 23:306;25:447,448;27:436;795; 28:562,559 as cancer drug 28:559 gastrointestinal toxicity by 28:562 immunotoxicity by 28:562 levels in mice plasma 28:567 myelotoxicity by 28:562 prophylactic effect against mylosuppression 25:447,448 5-Fluorouracil-induced myelosuppression 25:429 6-Fluoro-13-hydroxy-Nb-acetyltryptamine 29:344 synthetic fluorinated compounds 29:344 5-Fluoro-13-hydroxy-Nb-acetyltryptamine 29:344 as synthetic fluorinated compounds 29:344 Fluoxetine 22:672 Flurithromycin (8-fluroroerythromycin A) 13:166 synthesis of 13:166 Fluromalonate 13:82 Flustra foliacea 17:80,85,87,102,103; 18:689,692,693,708,725 Flustra papyracea 17:86 Flustrabromine 18:691 Flustramide A 18:691 Flustramide B 18:691 Flustramines 17:87 Flustramine A 18:690,691 Flustramine B 18:690,691
Flustramlne C 18:690,691 Flustramlne D 18:690,691 Flustramlne E 18:690,691 Flustramlne D-N-oxide 18:691 Flustraminol A 18:691 Flustraminol B 18:691 Flustrarine B 18:690 Flustriidae 18:690-693 Flutropium 22:738 FMBoA 27:211 FMDV 24:524 activity of actinoplanic acids against 24:524 FMN-binding domain 26:920 FNE 8:396 FOD (fast oligonucleotide deprotection) 13:361,267,268 Foenicuioside 1-IV 26:556,560 Foeniculum 21:619 oil of 21:619 Foeniculum vulgare Mill 5:473;21:599; 27:16;28:408 Foens-forming units (FFU) 24:483 Fogomine 10:567 Fogs grandifolia 5:472 Foliacraline 13:394 Folin-Ciocalteu method 21:508 Foliol 29:100 activity in NFkB bioassay system 29:100 Folk medicine 28:202;30:203,603 from genus Hypericum 30:603 use of Artocarpus venenosa in 28:202 use of ginseng root in 30:203 Follicle-stimulating hormone 27:796 Fomes annosus 21:212,232 Fommanosin 13:6 Food mutagens 8:378,388,389 Food preservation 21:617 Footprinting 5:580 Forbeside A (versicoside A) 7:288,293 Forbeside B (glycoside B2) 7:288,293 Forbeside C (asterosaponin 1) 7:288, 293 Forbesides A-C 7:292 Force field method 9:281 Forest tent caterpillar 24:865 bioassay of 24:865
327 Formaldehyde dimethyl dithioacetal 6:311 (S)-Formaldehyde di-p-tolyl dithoacetal S-oxide 6:346,437 in (S)-propranolol synthesis 6:346,437 synthesis of 6:343,344 Formaldehyde induced arthritis 25:46 Formalin 30:205 inflammatory pain induction by 30:205 neurogenic pain induction by 30:205 Formalin test 30:207 activity of 13-narin-II8-4'-OMeeridictoyol in 30:207 role ofbiflavonoid 30:207 Formamidokalihinols 21:366 Formaononetin 28:228 biological activity of 28:228 Formation 27:346,877 of(+)-abscisic acid 27:346 of(-)-abscisic acid 27:346 of (HOABA) 27:346 ofphaseic acid 27:346 Formic acid 28:384 as miticide 28:384 Formica 6:454 Formicids 6:421 (+)-N-Formylcyclomicrobuxeine 2:196,197 Formononetin 26:745;28:224,241 anti-microbial activity of 28:224 anti-Helicobacter pylori activity of 28:241 Formosanin C 21:651 Formosanine 25:25,26 Formycins A 10:356 Formycins B 10:356,357 Formylation 6:74 N-Formyl lactam 12:390,392 Formyl methionyl-leucyl phenylalanine (fMLP) 25:275 Formyl piperzinedione 12:66 3-Formyl rifamycin SV 21:421 1-Formyl- 1,4a-trans-isoquinolines 12:469 Na-Formyl- 12-methoxyechitamidine 1:36
3-Formyl-34a-trans-isoquinolines 12:469 2-Formyl-4,5-diphenyloxazole 14:598 1-O-Formyl-4'-Demethoxy-3',4'-methylenedioxymethylrocaglate 26:203 6-Formyl-5-isopropyl-3,7-dimethyl- 1Hinden- 1-one 14:328 4-Formyl- 8-hydroxyquinoline 2:232, 233;5:752,753 Formylation-diazotrans fer procedure 10:594,595 Formylchromane 4:495 7-Formyldehydrohernangerine 30:563, 589 activity in human cancer cell lines 30:589 cytotoxic effect of 30:589 from genus Hernandia 30:563 from Hernandia nymphaeiJolia 30.563 (+)-N-Formyldehydroovigerine 30:563, 589 activity in human cancer cell lines 30:589 activity in murine cancer cell lines 30:589 cytotoxic effect of 30:589 7-Formyldehydroovigerine 30:581 activity in human cancer cell lines 30:589 activity in murine cancer cell lines 30:589 cytotoxic effect of 30:589 ~H-NMR spectrum of 30:581 HREIMS of 30:581 hydrogen-bonding of 30:581 IR spectrum of 30:581 isolation of 30:581 molecular formula of 30:581 UV absorptions of 30:581 Na-Formylechitamidine 1:36 3-Formylguaiazulene 14:315 (+)-N-Formylharappamine 2:177,178 N'-Formyl-kynurenine 26:966,998 N-Formylnornantenine 30:563 from genus Hernandia 30:563 from Hernandia sonora 30:563 (+)-N-Formylnornantenine 30:563,589 activity in human cancer cell
328
lines 30:589 activity in murine cancer cell lines 30:589 cytotoxic effect of 30:589 8-Formyloct-5-enoate 26:86 wittig reaction of 26:65,66,70, 72,73,75,81,83-91 (+)-N-Formylovigerine 30:563,582,589 activity in human cancer cell lines 30:589 activity in murine cancer cell lines 30:589 cytotoxic effect of 30:589 Formyloxy compound 11:298,299
trans-7-Formyloxy-8amethylindolizidine 12:288,289 (+)-Formylpapilicine 2:182,183,204 3-Formylrifamycin SV 12:37 N-Formylvinamidine 2:398 ct-Formyl-tx-phenyl acetic acid 10:408 Forosamine 5:614 Foroxymithine 15:449 Forscarnet 24:486,487 as anti-viral agent 24:486,487 Forskalinone 20:672 from Salviaforskahlei 20:672 from Salvia hierosolymitana 20:672 Forskolin 10:183;13:659;23:488; 25:256,261,262,264,265,268,270272,275,276,489,490,496,539; 29:102 activity in APO bioassay system 29:102 Forsythia 26:327 Forsythia intermedia 5:489-491,492, 494;26:156,174,177,223 (-)-arctigenin from 26:223 Forsythia koreana 26:237 Forsythia mandshurica Rupr. var. japonica Maxim 5:505,514516,520,523-525,531 Forsythia spp. 5:511-513,521;26:156, 157,235 pinoresinol monoglucoside from 26:235 Forsythia suspensa 5:489,506,522, 592,616;21:595;24:855;26:156,237,2 41
inhibition of cyclic adenosine monophosphate (c-AMP) phosphodiesterase 24:855 Forsythia suspensa var. fortunei 5:475 Forsythia viridissima Lindley 5:505, 506,514,522;26:237 Forsythiaside 5:506,509,512-514;25:543 Forsythosides A 16:628 Fortimicin 4:118 Fortunellin (5-hydroxy-7-glucosylrhamnosyl-4'-methoxyflavone) 29:572 effects on HIV- 1 protease 29:572 Forward mutation test 27:303 Forysthide aglycone dimethyl ester 16:294-295 synthesis 16:294-295 Fosarium oxysporum 25:314 Fosfonomycin 6:352 Fostreus 27:883 as phosphatase inhibitor 27:883 Four component condensation 12:11, 115,117 Four-carbon polar annulation 6:17,21, 29,30 Fourier transform methods 5:3 FPP 7:110,122 FPP mimetics 24:414,415 structures of 24:414,415 FPTase inhibition 24:403-464 by andrastins 24:452,453 by arteminolide 24:457 by desmethoxy streptonigrin 24:454 by gliotoxin 24:452 by lupane triterpenoides 24:457 by monoterpenes 24:461 by patulin 24:458 by rhombenone 24:456 by saquayamycnis 24:480 by SCH 24:58,207,278,450,451 by solandelactones 24:455 by valinuoctins 24:459 FPTase inhibitor 24:439 cembranolide as 24:439 structures of 24:444 Fractional distillation 21:578 Fragaria spp. 29:571,579,582
329
Fragmentation 25:255 ofmanoyl oxide 25:245, 248-250,253-255 Fragmentation-recombination 10:412 of e~,[3-unsaturated methoxymethyl ester 10:412 to c~-hydroxymethyl unsaturated ester 10:412 Fragranol 7:208 from Artemisiafragrans 7:208 Fragrant odor 2:278 of liverworts 2:278 Framework molecular models 17:490 Framoside 26:327,334,343 Frangufoline 22:8 Frangula-emodin 22:646 FRAP 22:258 Fraser-Reid synthesis 12:13,14 Fraxetin 5:497,515-519;23:356;26:314, 315,318,331-334,336-340,342 Fraxetin dimethyl ether 5:516 Fraxidin 5:516,225;26:315 Fraxin 5:515,516,520,521;26:314,317, 318,331-334,336,338-340,342 Fraxin methyl ether 5:516 Fraxinol 5:516,517,519;26:315 Fraxinol methyl ether 5:516 Fraxinus 26:327,333,343 Fraxinus bungeana 26:317 Fraxinus chinensis 26:317 Fraxinus formosana 26:327 Fraxinus insularis 26:321 insularoside from 26:321 Fraxinusjaponica Blume 5:505,514, 515,520,521,523-525,531 Fraxinus ornus 26:313-319,327,328, 330,332,334-340,341,343-345 antimicrobial activity of 26:334 Fraxinus rhyncehophyllus 13:660 Fraxinus spp. 26:315-318 Fraxinus stylosa 26:317 cichorin from 26:314 esculetin from 26:314 fraxetin from 26:314 hydroxycoumarin esculin from 26:314 quercetin from 26:314 quercetin-3,7-digalactoside from 26:314
quercetin-3-galactoside from 26:314 quercetin-3-glucoside from 26:314 rhamnetin from 26:314 rutin from 26:314 Fraxinus uhdei 26:321 uhoside from 26:321 ;28:598 from calcigeroside C! 28:598 from calcigeroside D~ 28:598 from cucumarioside G2 28:598 (+)-Fraxiresinol 5:524,535-538,542 (+)-6-epi-Fraxiresinol 5:542 (+)-Fraxiresinol dimethyl ether 5:542 Fredericamycin A 16:27 antitumor agent 16:27 antitumor antibiotic 16:27 synthesis of 16:27-74 Free bases 27:170 of QBA 27:170 preparation methods of 27:170 pseudobase of 27:171 Free fatty acid 27:404 biological activity of 27:404 Free radical condensation 10:355 Free radical cyclization 3:326 Free radical deoxygenation 6:21 Free radical scavenging activity 22:314 Free radicals 30:221,224 role in aging 30:224 role in atherosclerosis 30:224 role in cancer 30:224 role in cardiac diseases 30:224 role in diabetes 30:224 role in human diseases 30:224 role in inflammation 30:224 role in intestinal diseases 30:224 role in neurodegeneration 30:224 role in reperfusion injuries 30:224 role in respiratory disorders 30:224 Free sugars 10:389-394 Free-energy 27:340 of ABA 27:340 Freelingyne 10:167 synthesis of 10:167 from Eremophila freelingii
330 15:233 from E. rotundifolia 15:233 Fremy's salt 9:456,457,10:120,121; 14:780;19:653 French paradox effect 27:430 French research groups 29:498 homochiral (+)/(-)-calystegines B2 synthesis by 29:498 Frenolicin 4:591,592,594,609 synthesis of 4:591,592,594,609 5-O-Freuloylquinic acid 25:920 4-O-Freuloylquinic acid 25:920 Fridelane-type triterpene 30:697 Fridelin 27:590 4,9-Fridodriane 25:867 Frido-oleane 23:692 Friedal-Crafts acylation 8:16,13:448, 18:234 Friedal-Crafts reaction 1:499-501; 5:485;10:312,313;11:140,318,319; 14:7,670-676,681-684 ;19:306; 20:692 intramolecular 10:312,313, 11:140 Friedelane 25:54,59 Friedelan-3,21-dione 5:744,746 Friedelan-3fl-ol 7:167,168;22:536,542 Friedel-Crafts alkylation 6:61,62,74, 75;10:376;18:231 Friedel-Crafts annulation 18:70 Friedel-Crafts products 6:309 Friedelin 5:744,746;7:147,148,150, 161,162,189;18:770;21:690;23:702; 30:719 structure of 30:719 synthesis of 3:435 Friedelin derived triterpenes 7:145-153 epi-Friedelinol 27:590 Friedlander reaction 3:386 2 4 ,3 0-dino r-D: A-Friedoo l eanane 22:102 24-nor-D:A-Friedooleanane 22:102 Friedo-oleanenes 7:149,150 from Cassine balae 7:149,150 Fritsch-Buttenberg-Wiechell rearrangement 18:171 from anacardic acid 9:341 Fromia monilis 15:60 Frondogenin 7:277
Frondoside A 15:92 Frondoside B 15:94 Frondoside C 28:599 from sea cucumber 28:599 Frontal cortex 30:377 serotonin synthesis in 30:377 D-Fructofuranose 6:352,355,357,358 [~-D-Fructofuranosyl 1-thio-ct-Dglucopyranoside 8:322,325 a-D-Fructofuranosyl 1-thio-ct-Dglucopyranoside 8:323,326 synthesis of 8:323,326 D-Fructose 6:355 phosphorous analogues of 6:355 Fructose 7:181 Fructose content 27:311 Fructose-2,6-biphosphate 25:523 Fructose-6-phosphate-2-kinase 25:523 C-Fructosides 3:217 synthesis of 3:217 Fructus schisandraei 26:233 Fruit lactones 13:297 Fruit phenolics 23:745 in apples 745 in apricot 23:745 m cherry 23:746 m citrus 23:747 in grapefruit 23:747 in grapes 23:748 in lemon 23:747 in olive 23:749 in orange 23:747 in peach 23:749 in pear 23:750 m plums 23:750 in raspberry 23:750 in strawberry 23:752 Frullania dilatata 2:280,607 Frullania nisquallensis 2:280,471 Frullania tamarisci 2:278,280;9:254; 18:607,614,623 (-)-Frullanolide 18:607;20:471,472 Frullanolide 2:280,281 Frutescin 9:317 (+)-Fruticosonine 11:278,279,286 Frutinone A-C 7:415 5-FU (5-flourouracil) 25:450,453 5-FU derivatives 27:436
331 5-FU plus carp oil 28:566,568 effects on tumor growth 28:566 in sarcoma 180-bearing mice 28:566 5-FU plus tuna oil 28:566,568 effects on tumor growth 28:566 in sarcoma 180-bearing mice 28:566 5-FU treatment 25:449 Fuchs synthesis 18:892-895 Fuchsia 29:572 Fuchsiaefoline 5:128,387 Fucogalactomannans 5:289 Fucoidan 30:55-57,399,405 against human CMV 30:405 antitumor activity of 30:56 as antiviral agent 30:405 effect on angiogenesis 30:56 effect on body 30:56,57 effect on liver metastasis 30:55 effect on spleen or adipose tissue weight 30:56,57 effect on thymus 30:56,57 effect on tumor growth 30:55-57 from Fucus vesiculosus 30:399 from Laminariajaponica 30:56 9-(13-D-Fucopyranosyl) adenine 4:232 Fucosanthin 7:320,321 L-Fucose 23:163 et-L-Fucose 29:557 affinity chromatography of anti29:557 agar diffusion pattern of 29:558 as glycoconjugate 29:557 isoelectrofocusing of 29:559 Fucose 286-289,292-294,302 ~-L-Fucosidase 12:349 Fucosidases 7:41 Fucosterol 5:408,7:124 Fucosyltransferase 10:500,501 Fucoxanthin 6:133-137,139,141,142, 146;10:153 ;20:583,584;30:531 Fucoxanthin oxonium ion 30:518,519 structure of 30:519 Fucoxanthinol 6:135,136,142,143 Fucus garderi 26:1152 Fucus vesiculosus 25:717,725 Fuerstione 19:405
5-FU-induced adverse effect 25:449 5-FU-induced suppression of bone marrow hematopoiesis 25:454 Fukiic acid (phenolic acid) 29:582 effects on collagenase 29:582 synthesis from fukinolic acid 29:582 Fukinolic acid (phenylpropanoid ester) 29:582 effects on collagenase 29:582 (+)-Fukugetin (morelloflavone) 5:758 Fukumoto's approach 22:235 Fulica atra 5:837 Fuligo septica 21:413,29:236 fuligorubia A from 21:413 Fulvene 22:197,204,210,220 Fulvine 1:272,273 synthesis of 1:272,273 Fulvinic acid 1:263 synthesis of 1:263 Fulvoderivatives 7:459,460 Fulvoharpagide 7:459,460 Fulvoipolamiide 7:458,459 Fulvoiridoids 7:458 Fulvolamiol 7:459,460 Fulvoplumeirin 7:441,458,459,656 Fumagillin 22:261 ;26:458,459 Fumagillol 26:459 Fumarate dehydrogenase 26:800 Fumarates 8:142-144 Fumaric acid 7:180 Fumaricine 1:198,199,219 Fumaritridine 1:208,209 Fumaritrine 1:208,209,211,212 Fumarofine 1:207,209-211 Fumonisins 6:219,220,252;9:203, 204,214,215;13:530-533 Funco oreganus 5:836 Functional bioactivity 30:813 of [Tyr)Me)2-Phe] peptides 30:813 of Tyr(Me)2-Phe-NH2 30:813 of d-Tyr(Me)2-Phe-NH2 30:813 of Tyr(Me)z-d-Phe-NH2 30:813 of d-Tyr(Me)2-d-Phe-NH2 30:813 of Tyr(Me)2-Phe-G-V-V-NH2 30:813 of d-Tyr(Me)2-Phe-G-V-V-NH2
332
30:813 of Tyr(Me)2-d-Phe-G-V-V-NH2 30:813 of d-Tyr(Me)2-d-Phe-G-V-VNH2 30:813 Functional bioassay 30:809 activity of Tyr-Tic-NH2 in 30:809 activity of (Tic 2, LeuS)enkephalin in 30:809 activity of (Tic2)dermorphin in 30:809 activity of (tic2)DYN-A-(1-11)NH2 in 30:809 activity of (D-Ala,desGly2)DYN-A-(1-11)-NH2 in 30:809 activity of DYN-A-(1-11)-NH2 in 30:809 activity of (tic2)DYN-A-(1-13-)NH2 in 30:809 Functional group assays 21:508,511 Fungal [3-glucans 23:114,115 structure characteristic of 23:115 Fungal glycoprotein 25:396 Fungal polysaccharides 26:1124-1129 Fungal spore 9:219-248 Fungal tomatinase 25:316,321 Fungal toxin 1:289 synthesis of 1:289 Fungal-tomato pathogens 25:295,312 Fungi 2:341 Fungi and protozoa 18:785-814 Fungicidal activities 17:243;21:182, 192,266,275,276,277,285 ;28:146 of eliamid 28:146 Fungicidal isoflavans 27:498 Fungicidal properties 21:225 Fungicidal saponins 7:433 Fungicide thiazole 25:321 Fungicides 9:226;28:390 used of essential oil 28:415,390 Fungistatic activity 21:189,238 Fungitoxic compounds 22:73 Furan C-glycosides 10:349 Furan-based Diels-Alder approach 29:470 carbaaldopyranoses synthesis by 29:470
Furane 3:443 Furaneol 13:318,319 Furano flavonoids 26:744 1-Furano glycal derivative 30:455 conversion into 30:455 Furanoaphthoquinones 20:494 from Crescentia cujeta 20:494 Furanocoumarin 4:388,389,396,398; 7:433 ;9:402;18:978,979,985 ;20:497; 23:337,354 ;25:666 Furanodiene 29:88 activity in HPT assay system 29:88 activity in COX assay system 29:87 activity in iNOS assay system 29:87 activity in NFkB assay system 29:87 activity in NO assay system 29:87 activity in TPA bioassay system 29:103 Furano-guaian-4-ene 23:161 Furanoheliangolide sesquiterpenes 24:3,7,11-47 Furanoheliangolides 26:808 Furanoid 30:570 Furanoid C-glycosides 10:343,344 Furanoid compounds 3:55-58 synthesis of 3:55-58 Furanoid linalool oxide 25:141 cis and trans 25:143 Furanonaphthoquinones 5:16,17;30:314 13-Furanone 6:20 reaction wih 9-BBN 6:20 synthesis of 10:384 Furanosesquiterpenes 15:197,227-238; 23:202 Furanosyl C-glycosides 10:367 synthesis of 10:367 C~2-Furanoterpene furospongolide 25:697 Furanoterpene sulfates 25:688 Furanoterpenes 5:371,107;25:688 Furanoxides 30:530 Furans 17:324,585 Furanurono-6,1-1actone 14:180 Furanyl C-glycoside 10:391,392
333 Furfuryl (E)-2-(sulfonyl) acrylates 12:19 N-Furfuryl acryl amide cycloaddition 12:19 6-Furfurylaminopurine (kinetin) 7:90 Furfuryllithium 4:141,142 Furin 25:389 Furo [3,2-C]pyrid-4 (2H)-one 8:286 Furobenzazonine derivative 6:473,474 Furoclerodanes 30:709 Furodysin 21:361 (-)-Furodysin 6:28 from Dysidea species 6:28 oxy-Cope rearrangement in 6:28,29 synthesis of 6:28,29 Furodysinin 6:28;25:815 from Dysidea species 6:28 oxy-Cope rearrangement in 6:28,29 synthesis of 6:28,29 Furodysinin lactone thioacetate 25:815 Furofoline II 13:371,372,374 Furofuran lignans 26:200,201 ;30:594 antiplatelet activity of 30:594 Furofurans 24:756-762 Furoguaiacidin diethyl ether 17:325 synthesis of 17:325 Furohyperforin 30:611,613 structure of 30:613 Furohyperforin hydroperoxide 30:611, 613 as artifacts 30:611 structure of 30:613 2-Furoic acid 30:456 Furo-indoloquinolizine derivative 8:285 Furolabda-6,8-dien-17-oic acid 30:712 structure of 30:712 Furolabda-7-en- 17-oic acid 30:713 structure of 30:713 Furopelargone 23:815 Furopelargone A 23:813 Furopelargone B 23:813 Furopyridones 8:288,289 Furosin 30:208 analgesic effect of 30:208 Furospongolide 25:698 Furostane glycosides 17:136 Furostane-type saponin 21:675
Furostanol glycosides 17:116,135; 21:636 Furostanol saponin 21:636 Furst-Plattner effect 19:357 Furuta 29:466 pyranoid carbasugars synthesis by 29:466 2-Furycarbinol 19:464,19:473 Furyl alcohol 16:655 Furyl carbinols 16:639,648,651 2-(2-Furyl)-3-(5-nitro-2furyl)acrylamide 21:584 23-Furylbrassinolide 19:280 2-Furylcarbinols 19:463-509 Furylfuramide 21:584 2-Furyllithium 30:458 Furyllithium reagents 11:440 Fusarentin-6,7-dimethyl ether 15:387 Fusarentin-6-methyl ether 15:387 Fusaria sp. 24:942 fusicoccins from 24:942 Fusaric acid 6:219,220;21:587 Fusarin A,C,D,E,F 13:526,527 Fusarin C 9:203,204,214,215 Fusarins 6:250,252 biosynthesis of 6:250,252 from Fusarium moniliforme 6:250,252 Fusarium 6:201-259;9:201-208;13:519, 524-529;21:213,216,227,233 ;22:57; 26:464,482;27:158 Fusarium acuminatum 9:204,213; 13:535 Fusarium avenaceum 9:204,205, 213,214;13:526,535 Fusarium compactum 13:536;29:575 Fusarium crookwellense 9:205;13:526 fusarin C from 13:526 Fusarium culmorum 4:250,204-208, 212,648;13:519,520,526;27:225,382 Fusarium equiseti 9:204;13:543, 545;28:121 HIV inhibitory activity of 28:121 Fusarium graminearum 9:204-208,216, 524,543 Fusarium heterosporum 29:111 Fusarium larvarum 15:381,386
334
Fusarium lini 18:807
monohexosylceramides from 18:807 Fusarium merismoides 9:204 Fusarium moniliformes 9:203205,214,215;13:524,526,530 Fusarium nygamai 13:530 Fusarium oxysporum 9:204;21:189,196, 199,210,217,223,232 ;23:139,355 ;25: 293,295,296,299,305,311,312,313, 317,319,320,322 Fusarium oxysporum f. sp. cucumerinum 9:238 Fusarium poae 9:204,314,315,526 Fusarium proliferatum 13:530 Fusarium roseum 13:543 Fusarium sambucinum 9:204; 13:526,543; 25:317 Fusarium semitectum 9:204 Fusarium solani 9:204;25:303,305, 307,314,316,317;26:404,405,418 monohexosylceramides from 18:807 Fusarium sporotrichioides 6:247,204, 205,208-213;13:526 Fusarium subglutinans 13:530 Fusarium toxins 9:201-208 Fusarium tricinctum 9:205 Fusarium udum 21:240 Fuscoside B 29:103 andalusol as 29:109 andrographolide as 29:109 cafestol as 29:108 kahweol as 29:108 sarcophytol A as 29:104 structures of 29:105 Fused azacycloundecine systems 6:496 synthesis of 6:496 cis-Fused bicyclic furanone 29:452 carbafuranose synthesis from 29:452 cis/trans-Fused decalones 14:460 Fused eight-membered ring systems 6:468-474 Fused eleven-membered ring system 6:494-497 Fused lactone nucleoside synthesis 4:252
Fused nine-membered ring system 6:472-482,483-493 Fusicoccin 25:374 Fusicoccum amygdali 15:385 Fusicoplagins A-D 2:81 Fusidic acid 21:237;22:247 Fusidienols 24:443 Fusidium coccineum 21:231 Fusioccane 3:93,94 Fusion reactions 4:236,38 Fusion technique 4:222 Fusobacterium nucleatum 4:195 Futoenone 8:159;26:245 synthesis of 8:159 Futoquinol 8:169,170;26:245 synthesis of 8:169,170 G-90 30:841 as ot plasminogen activator 30:841 (+)-GAI 6:178-181 synthesis of 6:178-181 GAI2 6:172,194 GAI2 aldehyde 6:171,172,186 GAI3 72,187 GAi9 6:188 biogenesis of 6:188 from bamboo shoots 6:187 GA24from 6:188 GA44 from 6:188,189 GA20 6:186 from GAs3 6:186 GA24 6:188,189 GA3 methyl ester 8:117 synthesis of 8:117 GA31 8:117 synthesis of 8:117 GAg2 6:191-193 synthesis of 6:191-193 GA36 6:172,189 GA37 6:184,185 synthesis of 6:184,185 GA38 6:184,185 synthesis of 6:184,185 GA4 6:172,176,168,202,209 (+)-GA4 6:178-181 synthesis of 6:178-181 GA44 6:186,188
335 GAs3 6:186,188 GA69 6:191 GA7 6:172,186,195,201,202,209 GAT0 6:191 GA9 6:172,194 GA9 methyl ester 6:204 GABA (,/-aminobutyric acid) 1:89; 13:514;21:84 ;25:30,536,537;30:627, 782,783,787 effect on blood pressure 30:783 effects of glutamic acid decarboxylase (GAD) 30:783 effects of hyperforin inhibitor 30:627 hypotensive effect of 30:782 in spontaneously hypertensive rats 30:783 in systolic blood pressure in SHR 30:783 synthesis of 13:514 GABA agonist 25:528 GABA antagonists 21:69 GABA gated Cl-channels 25:528 GABA receptors 21:69,95;25:531 GABA transporter 25:537 GABAA 21:672,673;22:666 GABAA receptor 21:14,19,101,269,270; 25:529,895 ;30:203 interaction with ginseng 203 GABAB 21:14,672;22:666 GABAB receptor 21:20;25:530; 30:203,787 effect in SHR 30:787 G-protein-linked receptor type 25:530 interaction with ginseng 30:203 GABA-benzodiazepin-chloride channel receptor 21:672 (+)-Gabaculine 13:509,510 synthesis 13:509,510 GABA-ergic neuroreceptors 21:5 GABA-ergic receptor 21:68 Gabapentin 22:508 Gabunamine 5:124 Gabunine 5:124 G-Actin 22:33 GADPH 21:229 Gaeumannomyces graminis 25:304
Gaeumannomyces graminis vat tritici 21:186,196,199,204,210 GaINAcfll --~4[NeuAc a2--~3)Galfll 4Glcfll--+' 1 Cer 5:488 Gajasmin 16:298 [3-Galabioside 14:149 Galactal 7:59 [3-D-Galactan 5:275,278,279 Galactan 5:276,300 Galactinol 18:396 Galacto-configuration 4:147,148 D-Galacto-hexodialdopyranose 4:163,164 Witting olefination of 4:163,164 Galactomannan 5:279,286,289,290, 292,293,295,301,302,306-309,312, 313,325;26:148;27:511 Galactonic acid 8-1actone 2:163 Dc~-D-Galactopyranose 27:511 D-Galactopyranose 6:376 Galactopyranose 7:47 Galactopyranosides 5:657 [3-D-Galactopyranosides derivatives 7:52-54 3-O-[3-D-Galactopyranosyde 27:477
4-S-~-D-Galactopyranosyl-4-thio-Dgalactose 8:335 4-S- [3-D-Galactopyranosyl-4-thio- s-Dgalactopyran-oside 8:335 4-S-[~-D-Galactopyranosyl-4-thio-Dglucose 8:335 6-S-[3-D-Galactopyranosyl-6-thio-Dglucose 8:338,339 synthesis of 8:338,339
3-O-~-D-Galactopyranosyl-D-galactose
7:137 4-O-c~-D-Galactopyranosyl-~-Dgalactopyranoside 14:149 Galactose 7:153,158,294;22:312 D-Galactose 4:29,130,197,198,'27:506 L-Galactose 4:197,198 Galactose oxidase 7:71,72 Galactose prodrugs 21:161 biological behaviour of 21:161 synthesis of 21:161 Galactose rich acidic glycoprotein 25:453,454
336
D-Galactose-molybdate complex 15:429 ot-Galactosidase 7:38,39,567,568; 21:161,167 [3-Galactosidase 7:40;10:470,471, 567,568;22:739;25:210 inactivation by [3-galactoside analogue 7:40 inhibition by aminoglycopyranoses 7:47 inhibition by conduritol C cisepoxide 7:38 inhibition by conduritol C transepoxide 7:38 inhibition by [3-galactosyl amines 7:44 inhibition by nitrophenylthiogalactoside 7:48 Galactosidases 7:39,50,52,65 fromE, coli 7:39,50,52,65 Galactosidasic 24:999-1001 enzymatic activity 24:999-1001 ot-D-Galactosidation 14:150 of methyl 2-O-benzyl-4,6-Obenzylidene- 13-D-galactopyranosides 14:150 [3-Galactoside analogue 7:39,40 13-Galactoside derivatives 7:52,55 Galactosides 7:48 [3-Galactosides 8:315 Galactostain 7:41,42,267 from Streptomyces lydicus 10:542 mammalian [3-galactosidase inhibitor of 10:542 Galactostatin lactam 10:543,550 ot-D-Galactosyl prodrug 21:176 Galactosyl transferase 10:468,500,501 [3-Galactosylation 10:470 t~-Galactosylceramides 18:460 6-O-[3-D-Galactosyl-D-glucose 27:521 [3-(1-4)Galactosyltransferase 10:484 D-Galacturonic acid 4:198;6:363;7:181; 27:506 Galacturonorhamnans 26:1156 Galangin 22:328;25:541;26:752 Galanin effect 27:799,800 Galanin receptor antagonists 27:799
Galanolactone 23:801 Galanthamine 4:3,4,13,21;20:325,346, 370,385 ;21:52,84,102,748 ;22:5,30; 26:614 Galanthine 26:614 Galantinic acid 12:487 Galaxura marginate 25:704 Galeon 17:371 (+)-Galeon 26:899 Galeopsis angustifolia 25:251 Galeopsis ladanum L. 22:521 Galinum sinaicum 26:220 bis-glucoside derivatives from 26:220 Galiosin 26:657 Galipine 3:385,386 Galium 4:400;26:631 Galium sylvaticum 22:521 Galium verum L. 22:521 for epilepsy and hysteria 22:521 Galleria mellonella 22:384 Gallic acid 23:537,551,740,746; 26:359,798;28:280;30:208 analgesic effect of 30:208 derivatives of 30:208 design of 30:208 structure of 28:280 Gallic Wars 19:140 Gallicin 7:230 Gallic-p-coumaric acid 26:359 Gallic-sinapic acid 26:359 Gallocatechin 22:362;23:743,749; 25:943;26:748 (+)-Gallocatechin 23:745 Gallocatechin 3-gallate (flavan-3-ol) 29:585 effects on proteasome CHYlike activity 29:585 Gallocatechin-3-gallate 23:743 Gallotannins 23:750,752 Galloylation 21:543 Gal-N cyctotoxicity 21:656 Galphimia glauca 22:521 for epilepsy 22:521 Galpinone 20:276 Galsky potato disc method 9:386 Gambierdiscus toxicus 21:300;25:730 Gambirtannine 1:100,101 Gambusia affinis 21:365
337 Gametocyte 25:329 Gamma aminobutyric acid 21:10,19 Gamma linoleic acid 13:659 Gamma-elimination 8:420 Gancaonin C 28:228 biological activity of 28:228 Gancaonin E 28:228 biological activity of 28:228 Gancaonin G 28:228 biological activity of 28:228 Gancaonin H 28:228 biological activity of 28:228 Gancaonin I 28:228,243 anti-Helicobacter pylori activity of 28:243 anti-microbial activity of 28:224 biological activity of 28:228 Gancaonin O 28:228 biological activity of 28:228 Gancaonin P 28:228 biological activity of 28:228 Gancaonin Q 28:228 biological activity of 28:228 Gancaonin R 28:226 anti-human immunodeficiency virus (HIV) activity of 28:226 biological activity of 28:228 Gancaonin S 28:228 biological activity of 28:228 Gancaonin U 28:228 biological activity of 28:228 Gancaonin V 28:228 biological activity of 28:228 Gancaonin Y 28:228 biological activity of 28:228 Gancaonol B 28:224,243 anti-Helicobacter pylori activity of 28:243 anti-microbial activity of 28:224 Gancaonol C 28:243 anti-Helicobacter pylori activity of 28:243 Ganciclovir 21:698;24:474,486 as anti-viral agent 24:474,486 synergistic interaction with 21:698 Ganervosin A 15:138,146,155,173 Ganervosin B 15:141,173
Ganglionic-type nicotinic receptor 21:95 Ganglioside 18:486,786,788 Ganglioside GM3 16:88 Ganglioside GM4 8:343-344 Ganglioside GM5 18:486 from Anthocidaris crassispina 18:486 Gangliosides 7:307,10:459 Ganoderic acid F (12-acetoxy3,7,11,15,23-pentaoxolanost-8en-oic acid) 30:64 13C-NMR of 30:64 effects of 30:63 effects on hemoglobin 30:63 H-NMR of 30:64 IR data of 30:64 MS analyses of 30:64 structure of 30:64 Ganoderma japonicum 23:115 Ganoderma lucidum 22:132;23:126,
133;26:449;30:56,58,60
antimetastatic effect of 30:58,60 antitumor effect of 30:58 effect on blood glucose 30:58 in treatment of arteriosclerosis 30:58 in treatment of arthritis 30:58 in treatment of bronchitis 30:58 in treatment of cancer 30:58 in treatment of diabetes 30:58 in treatment of hyperlipidemia 30:58 in treatment of hypertension 30:58 triterpenoid fractions of 30:60 triterpenoid from 30:56 Garaniol 20:20,31 Garbanzol 26:745 Garcigerrin A 7:444,445,457 Garcinia 7:444;22:658 Garcinia cambogia 22:658 Garcinia cowa 26:805 Garcinia gerrardii 7:444,445,457 Garcinia huillensis 22:658 Garcinia indica 22:658 Garcinia livingstonei 22:659 Garcinia mangostana 4:382,384; 27:902;29:573
338
Garcinia mannii 22:658 Garcinia ovalifolia 22:658,659 Garcinia polyantha 22:658 Garcinia spicata 5:757,758 Garcinia staudtii 22:658 Garcinia subelliptica 22:660 Garcinia thwaitesii 5:757,758 Garcinia xishuanbannanensis 22:658 Garcinol 22:658 Garcinone A 4:382,284 Gardenia cramerii 5:756,757 Gardenia fosbergii 5:756,757 Gardeniajasminoides Ellis 16:298 Gardenia sp. 5:756,757 Gardeniae 21:124 Gardenin A (flavone) 29:572 effects on HIV- 1 protease 29:572 Gardenin B 5:654 Gardenin D 7:227 Gardenoside 16:298 Gardneria nutans 15:491 Gardnerine 15:491 from Gardneria nutans 15:491 Gargugamblins 17:370 Garjasmidin 16:298 Garjasmin 16:298,299 Garlic 23:455,467 supercritical fluid extraction of 23:467 Garlic bulbs 23:460 Garlic clove 23:462 cross-section of 23:462 Garrya 6:174 Garryine 3:435 synthesis of 3:435 Garsubellin A 22:660 Garuga gamblei 17:370, Garuga pinnata 17:370,375-376;26:899 Garuga sp. 17:375;26:899 Garugamblins 17:378 Garugamblin- 1 17:386,389 Garugamblin-2 17:386 Garuganin 26:111,899 Garuganins 17:370,378 Garuganin III 17:386 synthesis of 17:386 Gas chromatography 21:536,578 Gas phase B3LYP calculation 30:549
GASPE spectrum 5:145 Gassman oxindole synthesis 3:320 Gasteria 22:580 Gasteromycetes 9:202 Gastric acid secretion 21:701 inhibitory effect on 21:701 St-4Gastric carcinoma 19:298 Gastric H+,K+-ATPase 25:612 Gastric hemorrhagic erosions 22:443 Gastric tubing 27:314 for gastrointestinal absorption 27:314 Gastrin receptor 25:611 Gastrin releasing peptide 27:800 Gastritis 17:137 Gastrodia elata 25:529 Gastrointestinal cancer 1:275 Gastrointestinal depression 30:799 due to analgesic alkaloid 30:799 Gastrointestinal diseases 30:56,691,747 use of Maytenus amazonica for 30:691 Gastrointestinal disorder 25:607 effect offlavonoids 25:607 effect on gastrointestinal disorder of 25:607,615 Gastrointestinal hormones 27:794 Gastrointestinal peptide-hormones 27:797 Gastrointestinal toxicity 27:436;28:559, 560-562;30:56 by doxorubicin 28:562 chitosan inhibitory effect on 28:561 due to cancer drugs chemotherapy 30:56 of 5-fluorouracil (5-FU) 28:560 of bilobalide 28:171 of chitosan 28:559 of fish oils 28:559 Gastroprotective agents 25:614 Gaucher's disease 7:39 Gaudichandioside A 27:14,24,25; 30:734 against certain cancer cells 30:734 medicinal uses of 27:447 Gaudichaudioside B 15:22 Gaudichaudioside C 15:22
339
Gaudichaudioside F 15:22;25:251 Gaudichaudol 25:269 Gaudichaudols A-C 30:734 structure of 30:734 Gaultheria procumbens 21:619 GB-2a 5:758 GB-I 5:758 GB-Ia 5:758 GC-mass spectrometry 21:579 GC-MS 21:579,583,584,607 G-coupled proteins 30:808 phosphorylation of 30:808 GDIBOA 27:188,209 synthesis of 27:210 GDIM2BOA 27:188,209 synthesis of 27:210 Gedunin 7:190,191 Geigeria burkei 14:450 Geigeria sp. 20:10 Geigerin 20:10 Geissman-Waiss lactone 13:484,485 Geissochizol 5:73,126;9:171 Geissoschizine 1:21,31 ;5:126,520,171 (+)-Geissoschizine 13:490,491 Geissoschizine-type alkaloids 5:71,73 (+)-3-epi-Z-Geissoschizol 14:722-724 (+)-Z-Geissoschizol 722-724 Geissoschizoline 1:34,38,39,41,42, 46,48 Geissoschyzine 26:97 Geissospermum laeve 1:124 Geissospermum vellosii 1:124 Geiwiz and Hasslinger 29:185 pisiferic acid synthesis by 29:185 Gel electrophoresis 2:19,114 Gelatinasic 24:999-1001 enzymatic activity 24:999-1001 Geldanamycin 5:434,592;21:420,435; 23:54,72,89,90,91 absolute configuration of 23:90 ansa moieties of 23:91 biosynthetic units of 23:90 related compounds 23:72 Gelliusins A,B 21:72 Gelonium multiflorum 9:265 Gelsamydine 15:483-486 Gelsedine 15:481,482 Gelsedine-type alkaloids 15:481-483
Gelselegine 15:483,484 Gelselegine-type oxindole alkaloids 15:483-485 Gelsemamide 15:472,473 Gelsemicine 15:482 Gelsemide 7:441;15:478,479 Gelsemine N-oxide 15:479 Gelsemine-type oxindole alkaloids 15:478-481,504,505 Gelsemium 15:465-515 Gelsemium elegans 15:466,472,473 akuammidine from 15:466 gelsemamide from 15:472,473 humantenine from 15:472 koumine from 15:475,476 11-methoxygelsemamide from 15:472,473 16-epi-voacarpine from 15:469 Gelsemium rankinii 15:465 Gelsemium sempervirens 1:125,465467 Gelsemoxonine 15:481,482 Gelsenicine 15:481,482 Gelsevirine 15:479 from Gelsemium elegans 15:479 from Gelsemium rankinii 15:479 from Gelsemium sempervirens 15:479 Gemin A 23:397 Gemin B 23:397 Genanial 25:133 Genatiana macrophylla 25:476 Gene experession control 5:580,581 Gene expression 30:373 Gene SLC18A2 30:380 role in vesicular monoaminetransporter type 2 (VMAT2) 30:380 General skeleton 26:190 of lignans 26:190 Generation 27:64,69-71,73,74,75,78, 79,83 of 13-oxo-9,11-octadecadienoic acid 27:73 of 13-oxo-9-hydroxy- 10octadecenoic acid 27:73 of 9S-hydroperoxy 10E, 12Z, 16Zoctadecatrienoic acid from 27:70,71
340 ofjasmonic acid 27:64,71-73 of 16S-hydroperoxy-9Z, 12Z, 14Eocta-decatrienoic acid (16SHPOTE) 27:70 of 13-hydroperoxy-9Z-11Eoctadecaenoic acid 27:69-71 of 2E-4-hydroperoxy-2-nonenal (4-HNE) 27:74,75,83 of 16-hydroperoxy- 10,12,14octa-decatrienoic acid 27:71 of LO" radicals 27:78,79 of traumatic acid 27:75 of epoxyaldehydes 27:82 of salicylic acid 27:63 Genes 4:267 synthesis of 4:267 Geneserine 21:84 Genetic duplication 30:370 of ancestral gene 30:370 Genetic mapping 9:606,607 (+)-Genipin 16:290,20:56 Genipin 7:441 Genista cinerea 27:272 Genista rumelica 22:428;25:612 luteolin, luteolin-7-glucoside and genistein from 22:428 Genistein 22:424,428,458,460,495; 25:544,546,593,613;26:750,751,754, 757,760,802,803 ;27:843,844 Genistein (4', 5,7-trihydroxy-isoflavone) 29:577 effects on aminopeptidase N 29:577 Genital warts 30:405 Genkwanin 26:219;30:727 as chemopreventive agent 26:219 structure of 30:727 Genotoxic agent 30:316 from Rubia tinctorum L. 30:316 Genotoxicity assays 26:675 Gentamicin C2 4:188 Gentamycin C la 115 Gentamycin X2 14:145 Gentiana compestris 22:521 Gentiana crassicaulis 22:521 for convulsions 22:521 Gentiana dahurica 22:521 for convulsions 22:521
Gentiana decumbens L. 22:521 for convulsions 22:521 Gentianafetisowii Regel 22:521 for convulsions 22:521 Gentiana macrophylla 22:521 for convulsions 22:521 Gentiana sp. 5:651;23:564;25:471 Gentiana tibetica King 22:521 for convulsions 22:521 Gentiana wutaiensis 22:522 for convulsions 22:522 Gentianaceae 25:471 Gentianine 6:528,529,444 Gentianine derived alkaloids 6:528,529 Gentianine series 6:522 Gentiobiose 8:349;15:436;25:968 Gentiopicroside 7:442;25:471 effect of gentiopicroside 25:471 serum ALT activity of 25:471 Gentisic acid 21:617 Gentosamine 14:50 Genus Astragalus 27:251,443,446 abrisapogenol B from 27:443,453 astragenol from 27:449 complogenin from 27:453 9,19-cyclo-5(x,9[3-1anostane from 27:447 cyclocanthogenin from 27:448 cycloalpigenin from 27:452 cycloalpigenin B from 27:449 cycloalpigenin C from 27:449 cycloalpigenin D from 27:449 cycloasgenin A from 27:449 cycloasgenin B from 27:558 cycloasgenin C from 27:448 cycloastragenol from 27:449 cyclogalegenin from 27:450 cycloorbigenin A from 27:452 cycloorbigenin B from 27:452 cyclopycnanthogenin from 27:450 dasyanthogenin from 27:451 3-dehydrocycloasgenin from 27:448 dihydroycloorbigenin A from 27:452 glycyrrhetic acid from 27:453 medicinal uses of 27:447
341
oleanolic acid from 27:453 oxytrogenin from 27:453 quisvagenin from 27:450 sapogenin from 27:448 sapogenin II from 27:453 saponins from 27:446 soyasapogenol B from 27:453 terpenoid sapogenins from 27:446 Genus Bupleurum L. 27:660 Genus Dorstenia 29:761 analgesic activities of 29:761 anti-infective principles from 29:761 anti-inflammatory activities of 29:761 anti-oxidant activities of 29:761 anti-rheumatic remedies from 29:761 anti-snakebite principles from 29:761 as chalcone source 29:761 as flavanone source 29:761 as flavone source 29:761 as flavonol source 29:761 as geranyl-substituted coumarin source 29:761 as prenyl-substituted coumarin source 29:761 chemistry of 29:761 cytotoxic activities of 29:761 5,3'-digeranyl-3,4,2',4'-tetrahydroxychalcone from 29:761 O-[3-(2,2-dimethyl-3-oxo-211furan-5-yl)butyl]bergaptol from 29:761 7,8-(2,2-dimethylpyrano-4'methoxyflavanone (dorspoinscttifolin) from 29:761 3 ', 4 '-( 2,2-dimethylp yrano-6prenyl-7-hydroxyflavonone from 29:761 ethnomedical information of 29:762 fig family of 29:762 in skin diseases 29:762 mulberry family of 29:762 occurrence of 29:761
pharmacology of 29:761 to treat rattlesnake bites 29:765 Genus Dorstenia (Moraceae) 29:761 analgesic activities of 29:761 anti-infective principles from 29:761 anti-inflammatory activities of 29:761 anti-oxidant activities of 29:761 anti-rheumatic remedies from 29:761 anti-snakebite principles from 29:761 cytotoxic activities of 29:761 in skin diseases 29:762 pharmacology of 29:761 to treat rattlesnake bites 29:765 Genus Hernandia 30:563-580 (-)-laetine from 30:564 (+)-actinodaphnine from 30:563 (+)-corytuberine from 30:563 (+)-hemagine from 30:563 (+)-hemandaline from 30:563 (+)-hemovine from 30:564 (+)-isoboldine from 30:564 (+)-isocorydine from 30:564 (+)-laurotetanine from 30:564 (+)-magnoflorine from 30:564 (+)-N-formyldehydroovigerine from 30:563 (+)-N-formylnornantenine from 30:563 (+)-N-formylovigerine from 30:563 (+)-N-hydroxyhernangerine from 30:564 (+)-N-me thyl-6,7- dime tho x yi soquinolone from 30:564 (+)-N-methylactinodaphnine from 30:564 5,6-dimethoxy-N-methylphthalimide from 30:563 6,7- dimetho xy-N-methylis oquinoline from 30:563 7-formyldehydrohernangerine from 30:563 7-formyldehydronornantenine from 30:563 7-formyldehydroovigerine from
342
30:563 7-hydroxy-6-methoxy- 1methylisoquinoline from 30:564 alkaloids from 30:563 antiplatelet aggregation effect of 30:560 atheroline from 30:563 backebergine from 30:563 benzenoids from 30:567 constituents of 30:563-570 dehydrohernandaline from 30:563 demethylsonodione from 30:563 hernandonine from 30:564 hernangerine from 30:564 hernanymphine from 30:564 isoindole from 30:563 isoquinoline from 30:563-567 laetanine from 30:564 laudanosine from 30:564 lignans from 30:567 lindearpine from 30:564 monoterpene from 30:569 N-(N-methylcarbamoyl)-Omethylbulbocapnine from 30:564 N-formylnornantenine from 30:563 N-hydroxyovigerine from 30:564 N-methylcorydaldine from 30:564 pyridine from 30:567 sterols from 30:569-570 Genus Hypericum 30:607,619 hypericin from 30:607 isohypericin from 30:607 pseudohypericin from 30:607 xanthones from 30:619 Genus Mortonia 23:665 Genus Morus 28:200 anti-inflammatory activity of 28:200 anti-tussive activity of 28:200 anti-pyretic activity of 28:200 Genus Ononis 30:138 resorcinolic from 30:138 Genus Pseudomonas 29:329 Genus Tanacetum 27:547
Genus Teucrium 23:591-648 biological evaluation of 23:591648 chemical evaluation of 23:591648 Geodia 25:768;26:488,1210 Geodia cydonium 25:718 Geodiamolide A 25:769 Geodiamolide C 25:769 Geodiamolide D 25:769 Geodiamolide E 25:769 Geodiamolide F 25:769 Geodiamolides 25:757,768 Geodiamolides A-T 25:768 Geosmin 26:353,354 Geothelphusa dehaai 19:647 Geothricum penicillatum 13:302 Geotrichum candidum 23:349;26:673 Geotrichum louberi 26:673 Geotrichum penicillatum 25:129 Gephyrotoxin 1:23,223,287,288,292, 385-389;4:606;6:449;7:11,10:186, 453;16:453;21:56 3-Gerandyloxy-6-methyl- 1,8dihydroxyanthrone 7:418-420,424 Geranial 13:333,17:433 Geranic acid 20:5;25:132,133,134 Geranii 27:413 corilagin from 27:413 Geranii herba 27:413,415 biological activity of 27:413,415 Geranii herba 27:415 Geraniin 27:840;29:572;30:208 analgesic effect of 30:208 effects on HIV-1 protease 29:572 Geraniol 7:100,101,104,105,107,108, 116,117,125,19:83;20:5;21:589,590, 612;22:392;25:125,132,134,136138,140,142,143,163,165;28:406,42 6;29:83 acaricidal properties of 28:406 activity in ODC assay system 29:83 activity in RAS assay system 29:83 as bioactive monoterpenoid 28:426 E-Geraniol 8:77
343 Z-Geraniol 8:77 Geraniol acetate 10:9,14 Geranium 29:572 Geranium macrorhizum 5:679 Geranium oil 25:132 Geranium thunbergii 17:421,428, 433;27:413 Geranyl acetate 15:227;25:136,164 from Eremophila abietina 15:227 Geranyl acetone 6:60 Geranyl bromide 4:386,386,391 Geranyl diphosphate 7:324;11:219-221 (+)-bornyl diphosphate from 11:219-221 (1R)/( IS)-[ 1-3H]Geranyl diphosphate 11:220,221 Geranyl geraniol 25:239 Geranyl geranyl phosphate 11:4 Geranyl geranyl pyrophosphate 11:24 Geranyl hydroquinone 5:440 Geranyl linalool 25:254 Geranyl linalyl pyrophosphate coaplyl PP 25:239,240 3-Geranyl-2,4,6-trihydroxy-benzophenone (phenolic ketone) 29:571 inhibition of Candida albicans aspartic protease 29:571 (5)-(+)-Geranylacetol 25:163,164 Geranylacetol 25:168,169 (E)-Geranylacetone 28:406 acaricidal properties of 28:406 8-Geranylapigenin 28:234 synthesis of 28:234 Geranylated monochalcones 29:774 5,3 '-(3,7-dimethyl-2,6- octadienyl)-3,4,2',4'-tetrahydroxychalcone as 29:775 4'-geranyloxy-4,2'-dihydroxychalcones as 29:775 poinsettiflin B as 29:774 proropensin as 29:774 Geranylfarnesol 6:111 Geranylgeraniol 15:253,20:26,28,30 Geranylgeranyl diphosphate 5:701; 7:321,322,324,325,327,330,348,351; 21:721 ;25:237,240,244 (E,E,E)-Geranylgneraniol derivatives 1:662-665
trans-Geranyllinalool 20:590 Geranyllinalool isonitrile 21:330 3-Geranyloxyemodin 7:418-420 9-Geranyl-a-terpineol 30:615 structure of 30:615 Gerinimum genera 27:755 Gerlach's procedure 6:542,543 (7S)-Germacra-1 ( 10)E,4( 15)-dien2[3,5cz,6~-triol 29:88 activity in TPA assay system 29:88 activity in PLA assay system 29:88 (7S)-Germacra-4( 15)Z,9-diene- 1or,2[3, 6[3-triol 29:88 activity in TPA assay system 29:88 Germacradiene 8:59 Germacradienolides 7:210 cis, cis-Germacradienolides 7:210,211 Germacrane 6:15,607;7:209,211, 212,214,216;29:88 activity in CRG assay system 29:88 activity in HPT assay system 29:88 curdione as 29:88 dehydrocurdione as 29:88 germacrone as 29:88 neocurdione as 29:88 Germacrane D 30:607,715,722 structure of 30:722 Germacrane lactone 8:195-201 Germacrane- 12,8-olides 7:231 Germacranolides 2:280,210,211 ;27:560 6,12-Germacranolides 24:806 Germacrene D 9:531,534;26:409, 413;27:573 Germacrene isoprenologue 15:278 (-)-Germacrene-D 6:540 Germacrenes 23:160 Germacrenoid structure 6:538,539 Germacrolides 7:210 Germacrone 8:178;23:825,833; 25:172,173 synthesis of 8:178 Germanocrenolide 26:808 Germination 9:219-248
344
Germination inhibitor 1:684 synthesis of 1:684 Gernaiol 25:132 Gernayl geranyl pyrophosphate 25:248 Gerrardine 7:192 Geseneriaceae 25:251 Gestogens 17:623 semi-synthesis of 17:623 Geumjaponicum 23:397;29:574 GF-109203 X 12:389 Ghosez cyclization 26:1230,1231 8-C-Ghycosylflavones 5:644 Giardia intestinalis 26:1063 C20Gibberelins 6:184-190 Gibberella cyanea 25:162,166 Gibberella fujikuroi 8:115,117; 24:938,942,954 ;25:253,255 diterpenes from 24:938 gibberellins from 24:938 Gibberella gaminis var. avenae 25:304,305,306,308,310 Gibberella pluicaris 25:293, 305,307,311,317,319 Gibberellane 25:241 Gibberellenic acid 6:199;25:245 as gibberellin 6:171,172,181-184 as gibberellin A3 6:171,172 from gibberellic acid 6:199 gibberellenic acid from 6:199 growth effect on root culture 17:425 total synthesis of 6:181-183 synthesis of 8:116 Gibberellic acid (GA3) 6:181-183,209, 100;7:100;8:115-120 C20 gibberellins from 6:186190 from Gibberella fujikuroi 6:172,186 in gibberellic acid 6:171 Gibberellins 6:171,194-209;8:115-135; 22:67,247 ;25:367,657 ;27:305 antheridiogens from 6:171,194209 partial synthesis of 6:186, 194-209 from gibberellic acid 8:115 homonuclear 8: ~H-IH-shift 8:117
mass spectrum of 8:117 synthesis of 3:435;8:115-137 Gibberellin A7 6:197-201 Gibberellin oxo esters 8:128 Gibberellin thioanalogs 8:123-127 Gibberellin-7-aldehydes 8:128 Gibberellins AI,A3,A4,Av,A9 7:188 Gibberellins GA4 8:115,119,120 Gibberellins GAs5 8:121,122 from 1[3-azido-3[3-hydroxy compound 8:121,122 synthesis of 8:119,121,122 Gibberellins GAs7 8:121,122 from GA3 8:121,122 synthesis of 8:115,121,122 Gibberellins GA60 8:121,122 from GA3 8:122 synthesis of 8:115,121,122 Gibberellins GA7 8:119 from GA3 8:119 synthesis of 8:115,119,120 allo-Gibberic acid 8:117 synthesis of 8:117 Gibberic acid 8:117 synthesis of 8:117 Gibbonsia elegans 17:94;25:787 Gibbs test 22:489 Giffordene 21:306 Giffordia mitct~ "ae 21:306 Gigantecin 9:3~,5-397;17:277;18:221, 222 Gigantenone 6:554-556 (+)-Gigantenone 6:555,556 Gigantetronenin 18:221 Gigartina skottsbergii 30:402 carrageenans from 30:402 Gilben's reagent 26:1245 Gilman reagent 22:206 Gilvocarcin 10:343,374 Ginamallene 5:369,370 Gindarine 21:56,57 Gingenoside Ro (chikusetsusaponin V) 24:147,148 Ginger glycolipid A 23:851 Ginger glycolipid B 23:851 Gingerenone A 23:849 Gingerenones A, B and C 17:378 (6)-Gingerol 23:818 (8)-Gingerol 23:818
345 Gingerol 9:321,328;23:846; 24:900;26:475 as an accelerator of the motility of digestive organs 24:900 as an antiemetic agent 24:900 biosynthesis of 23:848 effect of gingerol analogues on NA-contraction 24:902 effect of gingerol analogues on PGF2a- contraction 24:902 related compounds 24:900-902 Gingkolides 13:659 Ginkgo biloba L. 9:317,321,323,659, 660;21:591 ;24:297 ;26:929;28:165, 170;29:571 anti-depressant effect of 28:177 anti-oxidant activity of 28:179 anti-stress effects of 28:177 amentoflavone from 28:166 apigenin from 28:167 biological activities of 28:165 3 '-O-methylmyricetin-3-Orutinoside from 28:167 5'-methoxybilobetin from 28:166
Ginkgol 9:323 Ginkgolic acid 5:826-828,355,436,317; 21:590 Ginseng 13:660;25:182;30:203 activity in chronic pain model 30:203 as analgesic 30:203 interaction with bradykinin B2 receptor 30:203 interaction with GABAA receptor 30:203 interaction with GABAB receptor 30:203 interaction with neurokinin NK~ receptor 30:203 Ginseng root 30:203 use in abdonminal pain 30:203 use in chest pain 30:203 use in folk medicine 30:203 use in neuralgia 30:203 use in pain 203 use in toothache 30:203 Ginseng rubra 21:675 ginsenosides from 21:675
Ginseng saponins 21:651 ;30:203 action of 30:203 Ginsenoside Rb~ 21:645,653,667,669, 670;25:958;27:859,860 Ginsenoside Rb2 21:638,645,653,666, 669,670 Ginsenoside Rb3 21:669 Ginsenoside Rg~ 24:146;27:424 biological activity of 27:424 Ginsenoside Ro 21:651,657,670 Ginsenoside Ryl 25:958 Ginsenoside-Re 21:645,653,669,670 Ginsenoside-Rg~ 21:645,653,669-671 Ginsenoside-Rg2 21:670,671 (20S)-Ginsenoside-Rg2 21:672 20(R)-Ginsenoside-Rg3 21:638 20(S)-Ginsenoside-Rg3 21:638 Ginsenosides 15:191;30:203 action of 30:203 effect on central nervous system 30:203 effect on nociception 30:203 effect on spinal region 30:203 effect on supraspinal region 30:203 voltage-sensitive calcium channels blockade by 30:203 Ginsenosides-Rc 21:653 Ginsenosides-Rd 21:645,653 Gissampelos insularis 25:478 Gitaloxigenin 15:362 Gitaloxin 15:362 Gitoxigenin 15:362 Gitoxin 15:362 6-Glucuronide 22:10,24 Gizzerosine 1:679,780 synthesis of 1:679,780 GL-311 26:162 used for anticancer treatment 26:162 Glabranin 28:228 biological activity of 28:228 Glabrene 28:224,228 anti-Helicobacter pylori activity of 28:241 anti-microbial activity of 28:62,224,228,257,293 biological activity of 28:228
346
Glabridin 27:846;28:228,241 anti-Helicobacter pylori activity of 28:241 anti-microbial activity of 28:224 biological activity of 28:228 Glabrocoumarone A 28:229 biological activity of 28:229 Glabrol 28:228 biological activity of 28:228 (+)-Glabrol 4:378,380 synthesis of 4:378,380 Glacialosides A,B 7:299 from Marthasterias glacialis 7:299 Glaciolide 17:14,15 Glanduliferol 6:63,64 Glaucarubin 7:394,398,660;13:660; 26:837 Glaucarubinone 7:379,383,392,394, 395,396,7:398,72,79,80,105;11:79, 80,105 Glaucarubol 7:394 Glaucasterol (papakusterol) 7:396,398; 9:37;23:299,301,304 from Pseudothesis species 9:37 from Sarcophyton glaucum 9:37 Glaucine 3:424,425;21:79 synthesis of 3:424,425 (+)-Glaucine 16:506,514 S-Glaucine 16:507 Glaucium genera 27:163 Glaucocalactone 15:141,149,158,172 Glaucocalyxin A 15:172 Glaucocalyxin B 15:172 Glaucocalyxin C 15:112 Glaucocalyxin D 15:114,121,128,172 Glaucocalyxin E 15:114,121,128,172 GLC method 25:435 (-)-Glechomafuran 20:660 Gleditsiajaponica 15:195;21:643; 24:241,243,246 saponin C from 21:643 Gleditsia macracantha 26:1140 Gleditsia saponins 15:191 Gleditsia triacanthos 26:1115,1116, 1139,1143 Gleditsiasaponin C 21:643,664 Gleicheniajaponica 25:251,276 Gleosporium fructigenum 18:715
y-Gliadin 25:320 Glial cell 27:806 Gliocadin A, C 21:235 Gliocadium virens 21:238 Gliocadium virens deliquescens 21:238 Gliocadium virens fimbriatum 21:238 Gliocladic acid 21:230 Gliocladium deliquescens 21:225 Gliocladium fimbriatum 21:182,218 viridol from 21:238 Gliocladium flavofuscum 21:238 Gliocladium fujikuroi 21:227 Gliocladium sp. 5:370;21:198,203, 215,224,227,235,237,238 gliocladins A-C from 21:235 Gliocladium vermoesenii 21:207 nectriapyron from 21:207 vermopyrone from 21:207 Gliocladium virens 21:218,229,232,239 gliodeliquescins from 21:225 viridin from 21:238 viridol from 21:238 Glioma cells 27:797 Gliotoxin 24:452,545 antiviral microbial-derived compound 24:545 FPTase inhibition by 24:452 Gliovictin 25:828 Gliovirin 21:218,219,238 Glisoflavanone 28:228 biological activity of 28:228 Globicin 7:235 Globodera 26:429,432,467,471 Globodera pallida 26:229,474 Globodera rostochiensis 26:229,430, 461,474,477,486,487 Globularidin 7:440 (-)-4-epi-Globulol 14:359 Globulol 30:724 Gloemerella cingulata 25:64,166-168 Gloeoplyllum sepiarium 23:354 Gloeosporium lacticolor 15:351 Gloeosporone 9:220,229,234,240243,245-247;10:233 synthesis of 10:233 Glomerella cingulata 5:278,415,228, 230,240;23:112,115;29:590 extracellular polysaccharide of 23:112
347
Glomerella fructigene 9:230,239 Glomerella glycines 9:230,239 Glomerella gossypii 9:230,239 Glomerella sp. 9:228,230,239 Glomerella tucumanensis 9:230,239 Glomerellan 23:115 Gloria superba 5:47 Glossina spp. 26:785 Glossodoris quadricolor 28:650 latrunculin B from 28:650 Glossostemon bruguieri 28:425 D-Glucal 2:162 Glucal triacetate 11:356,357 1,3-fl-D-Glucan 22:62 Glucan 5:276-280,287,288,291,292, 295,299,305,307,308,310-312,316, 321;23:107,115,123,126 13C-NMR assignments of 23:123 Glucanase 7:32-36,59,60;22:75 ot-Glucanase 7:60 endo-Glucanase (take-amylase) 7:34,35,42 13-1,3-Glucanasis 21:224 Glucanhydrolases 21:224 Glucan-polyolalcohol 5:318,319 [3-Glucans 23:107,111,115,135 13C-NMR spectra of 23:111 chemical structure of 23:111 functional derivative of 23:125 isolation of 23:110 occurrance of 23:108 structure-functional activity of 23:139 supramolecular structure of 23:115 c~-Glucans 23:109 Glucans 25:396 [3-D-Glucans 5:287,292,295,307,308, 310-315,316,320,321 c~-D-Glucans 5:287,307,309,310 exo-~-Glucans 7:59,60 D-[3-Glucans 107-152 of fungi 23:107-152 of yeast 23:107-152 Glucansucrase 7:69 Glucantime 26:828 Glucoamylase 29:548 affinity chromatography of
29:550 affinity purification of 29:549 electrophoresis of 29:551 gel electrophoresis of 29:549 in beverages 29:548 in confectionaries 29:548 in industrial process 29:548 in processed foods 29:548 isoelectric focusing of 29:550,551 molecular structure of 29:550 purification of 29:549 use of 29:552 Glucoamylases 2:49,50,58,62,63, 321-360;7:49,34 ;10:497,504 Glucobioses 7:69 Glucocorticoid degradation 21:657 Glucocorticoids 22:97,115;25:463,516 Glucodextranase 7:58 Glucoferulic acid 5:476 D-Glucofuranose 6:359,360,369, 370,376 Glucogitaloxin 15:362 Glucomannan 5:306 Glucono-l,4-1actone 21:239 Gluconobacter oxydans 10:530 Gluconolactone 10:386,387;30.447 Gluco-octenitol 7:60,69 23-0-,8-D-Glucophyranosyl-25methyldolichosterone 18:495 2-O-fl-D-Glucophyranosyl-3,24diepicastasterone 18:529,532 3-0-,8-D-Glucophyranosyl-3,24diepicastasterone 18:529,541 23-0-,8- D- G lucoph yranos y 1-bras s ino Iide 18:522 Gct-D-Glucopyranans 5:307,310,317 D-Glucopyranose 6:352,355,370, 373,376 Glucopyranose 7:47 ~-D-Glucopyranose 1-thiolate derivative 8:318 D-Glucopyranose 3-O-triflate 8:343,344 [3-D-Glucopyranose monoester 27:522 c~-Glucopyranoside 19:369 p-Glucopyranoside 19:369 6-O-fl-D-Glucopyranoside 25:224
348 D-Glucopyranoside 6:357-359 N-(Glucopyranoside-3-yl)-peptide ester 6:406,407 Glucopyranosides 5:657 [3-Glucopyranosyl 23:113 structure of 23:113 Glucopyranosyl 1-deoxynojirimycin derivatives 7:42 et-D-Glucopyranosyl 1-thio-c~-Dmannopyranoside 8:347 13-D-Glucopyranosyl 1-thio-[3-Dglucopyranoside ([3,13-1thiotrehalose) 8:317 4'-fl-D-Glucopyranosyl 4-hydrogen7',8'-dihydro-4,4'-diapocarotene4,4'-dioate 30:528 4-S-c~-D-Glucopyranosyl 4-thio-Dglucose 8:331,332 6-S-13-D-Glucopyranosyl 6-thio-Dglucose 8:338,339 Glucopyranosyl fluoride 7:58 D-Glucopyranosyl moiety 30:813 pharmacological activity of 30:813 ot-D-Glucopyranosyl phosphate 14:151,152 23- O-fl- D- Glucopyrano syl-2-epi- 25methyldolicho-sterone 18:495 6-S-[3-D-Glucopyranosyl-6thiocyclomalto heptaose 8:340 6-S-c~-D-G lucop yranos yl-6thiocyclomaltoheptaose 8:340 6-S-[3-D-Glucopyranosyl-6-thio-c~-Dglucopyranoside heptaacetate 8:337,338 9-D-Glucopyranosyl-adenine 4:224,225 25-fl-D-Glucopyranosyloxy-24-epibrassinolide 18:539 26-fl-D-Glucopyranosyloxy-24-epibrassinolide 18:541 (-)-( trans-4 '-f3-D-Glucop yranos ylo x y- 3 'methoxycinnamoyl) lupinine 15:521 from Lupinus luteus 15:521 (-)-( trans-4 '- [3-Glucopyranosyloxycinnamoyl)lupinine 15:521 from Lupinus luteus 15:521 5'- 13-D-Glucopyranosyloxyepij asmonic acid 6:557
[3-Glucopyranosylvalienamine 13:233 c~-D-Glucopyranosyl-ot-D-mannopyranoside 8:347,8:348 synthesis of 8:347,348 D-Glucoronic acid 23:163 13-Glucoronidase inhibitor 25:263 [3-Glucoronidases 25:313 Glucoronides 5:645 Glucosaccharo-l,4-1actone 25:263 D-Glucosamine 14:186,461 Glucosamine 30:95 Glucosaminyl-chiro-inositol phosphate 18:434 Glucose 2:321,332,262,276-278,282284 ;7:136,139,142,181 ;27:394;30:58 propranol from 27:394 D-Glucose 23:163 a-Glucose 29:555 affinity patterns for 29:555 agar diffusion of 29:555 electrophoresis of 29:556 inhibition of 29:556 Glucose ester 27:520 ofnitropropanoic acid 27:520 Glucose isomerase 2:321 Glucose oxidase 7:71,104,105,111, 112;19:701;21:239 Glucose transporter 30:817 Glucose-l-phosphate 27:821 Glucose-6-phosphate 11:216,217 a-Glucosidase 10:498,514,526,431, 247-250,86-87;19:369-370 [3-Glucosidase 2:352,379,514,526,567; 10:568,249,250;19:357,365,369; 25:210,211,308,957,968 3,8-diepialexine inhibition with 7:14 6-epi-castanospermine inhibition with 7:12 australine inhibition with 7:15 castanospermine inhibition with 7:12 DMDP inhibition with 7:15 inhibition by 2-deoxy-2-fluoro-13D-glucopyranoside 7:36 inhibition by acarbose 7:47 inhibition by conduritol B epoxide 7:38,39
349
inhibition by nojirimycin heptitol derivative 7:43 inhibition by validamycin 7:47 Glucosidase 16:108;19:356;21:590 2[3-Glucosidase 5:471 Glucosidase 1 10:526,527 Glucosidase II 10:499,526,527 a-Glucosidase I 10:501 c~-Glucosidase II 10:501 c~-Glucosidase inhibition 21:592 [3-Glucosidase inhibitor 19:369 Glucosidase inhibitors 22:30 c~-Glucosidase inhibitors 7:46,48; 13:235-246;10:496 c~-Glucosidase inhibitory activity 21:592 [3-Glucosidases 22:739;27:778 biological activity of 27:778 Glucosidases I,II 7:12,13 Glucosidation 16:296 [3-Glucoside 23:27 1 '-O-Glucoside 27:354 3-O-[3-D-Glucoside 27:517 ot-D-Glucosides 2:330 13-D-Glucosides 27:520 of nitropropanol 27:520,521 a-Glucosides 8:226,359,361,366 Glucosidic bond 16:588 Glucosinolates 25:513,514;26:1074 enzymatic breakdown of 26:1074 Glucosyl chloride 8:359-362 9-Glucosyl derivative 4:224 9-Glucosyl derivative of theophylline 4:224 1-O-Glucosyl ester 27:354 fl-Glucosyl hydrolases 25:308 Glucosyl mannoside- 1-thio-a,ecdisaccharide 8:319,8:320 24-O-[3-D-Glucosyl officigenin 7:139,140 2-O-Glucosyl samaderine-C 23:299 Glucosyl stevioside 15:19 (11R)-6-O-f3-D-Glucosyl- 11,13-dihydrotatridin B 27:572 O-Glucosylation 5:516,520,525532,545
6-C-Glucosyldiosmetin 23:747 7-O-[3-Glucosylisofraxidin 5:515 Glucosyltransferase 2:322;27:354,778 Gluco-triflate 14:155 Glucotropolin 26:481 fl-D-Glucronides 25:263 D-Gluctol 6:357,358 ~-Glucuronic acid 16:81,84 Glucuronic acid 7:156;15:26,77;22:10; 25:89,94,102-104,119,465 D-Glucuronic acid 7:294 Glucuronic acid-based inhibitor 16:115 Glucuronic prodrugs 21:169 biological behaviour of 21:169 synthesis of 21:169 [3- Glucuronidase 16:81,82,84,88,90; 21:162,690;28:283 [3-D-Glucuronidase 21:175,176 [3-Glucuronidase activity 21:177 Glucuronidation 21:138 3-Glucuronide 22:10,24 Glucuronide 22:8 Glucuronide linkage 7:156-158 Glucuronide saponins 7:156-158 Glucuronides 28:288 bioactive phenolic compounds from 28:223 in urine 28:288 glyasperin D from 28:206 glycyrrhizic acid from 28:239 glyinflanin G from 28:206 glyinflanin K from 28:206 hispaglabridin A from 28:206 3-hydroxyglabrol from 28:206 3-hydroxyparatocarpin C from 28:206 isoderone semilicoisoflavone B from 28:206 kanzonol U from 28:206 kanzonol V from 28:206 kanzonol W from 28:206 kanzonol X from 28:206 kanzonol Y from 28:206 kanzonol Z from 28:206 licorice-saponin G2 from 28:239 liquiritigenin from 28:239 medicarpin from 28:206 1-methoxyphaseollidin from
350
28:206 4'-O-methylglabridin from 28:206 shinpterocarpin from 28:206 uses as licorice 28:204 D-Glucurono-6,3-1actone 18:396,442 D-Glucuronolactone 21:170 Glucuronomannan 26:1156 Glucuronomanno-protein 23:109 D-Glucuronopyranosyl 15:7 Glucuronoxylans 2:300 Glucuroxylomannans 5:294,326,327 (R)-Glumatic acid 12:322,325 Glunapin 26:481 Gluta renghas 9:319 Glutaconaldehyde 21:386 Glutamate 21:10,14,19,101 L-Glutamate 22:668,669 [3H]-Glutamate 30:208 Glutamate N-methyl-D-aspartate receptor (NMDA) 25:519 Glutamate /NMDA receptor 21:70 Glutamate receptors 30:208 Glutamate transporters 25:536 (S)-Glutamic acid 12:322,325,19:325 Glutamic acid 2:357;11:419 L-Glutamic acid 4:148,252,438,439; 6:438,439;13:607;14:633 Glutamic pyruvic transaminase (S-GDT) 21:651;25:935 Glutamine 6:409-413;25:320 Glutamine synthetase 7:6 y-Glutamyl cysteines 23:457,460 Glutamyl peptides 6:409,410 T-Glutamyl transpeptidase 23:460,461 T-Glutamylcysteine synthetase 26:913,951 Glutarate-CoA reductase 21:212 Glutarenghol 9:319 Glutaric acid derivative 11:118 Glutaric anhydride 13:540 Glutaric dialdehyde 14:739 Glutarimide 14:740,749 Glutarimide intermediate 6:410,411 Glutarimide rings 1:313 Glutathinonylspermidine 26:808 Glutathione 22:9,10;25:219,614,831, 930
Glutathione 5-transferase (GST) activity 21:585 Glutathione peroxidase (GPx) 9:109; 23:480 Glutathione peroxidase 9:109 Glutathione peroxidase (GSHPx) 22:309 Glutathione reductase (GRd) 23:480 Glutathione reductase inhibition 26:1036 Glutathione S-transferase (GST) 9:562,576,577;21:356;23:480;25:718 Glutathionyldehydroretronecine 22:13 Glutin-5-ene 25:59 Glutinane 25:53,59;30:65 Glutinol 7:150;21:690 Glutinopallane 17:154 Glutinosin 15:167-170,172;17:199 Glyasperin A 28:226,228 anti-human immunodeficiency virus (HIV) activity of 28:226 biological activity of 28:228 Glyasperin B 28:228 biological activity of 28:228 Glyasperin C 28:228 biological activity of 28:228 Glyasperin D 28:224,228,243 anti-Helicobacter pylori activity of 28:243 anti-microbial activity of 28:62,224,257,293 biological activity of 28:228 Glyasperin J 28:228 biological activity of 28:228 Glyasperin K 28:228 biological activity of 28:228 Glycals 4:223,59-62,337-352; 10:338-341 ;30:453-458 homologation of 30:455 synthesis from 30:453-458 Glycan 6:397-404;27:506 Glycanases 8:347-351 Glycanoxylans 26:1156 Glyceollin 26:473 Glyceollin I-III 26:473 (S)-Glyceraldehyde 14:765 L-Glyceraldehyde 16:99 D,L-Glyceraldehyde 6:359
351 Glyceraldehyde-3-phosphate dehydrogenase 21:229;26:913,951 Glyceraldehyde-3-phosphate (GAP) 25:134 D-Glycero-D-galactoheptose 4:195, 198,199 L-Glycero-D-manno-heptop yranose 11:429 D-Glycero-D-manno-heptose 4:195, 202,203 Glyceroglycol lipids 25:431 (1R,2R) [1-2H1, 3H]Glycerol 11:208 Glycerol 2:20 Glycerol tri-myristate 2:48,49 Glycerol-3-phosphate dehydrogenase inhibitory activity 21:591 L-Glycero-L-manno-heptose 4:195,197202,207,209 D-Glycero-L-manno-heptose 4:197,198 D,L-Glycero-pentopyranose 6:360,361 Glyceryl [3-galactoside 7:65 Glycidol 13:70 Glycine 4:115-118;21:10,14,19,50 Glycine max 15:196;25:93,105,669; 26:930;29:578,581,593,595,604 soyasaponin A3 from 15:196 Glycine receptor 21:72;25:530 Glycine soya 25:93,101 Glycine-gated Cl-channels 25:530 Glycine-modulatory site 22:25 Glycine-rich protein 25:394 Glycinoeclepin A 22:96;26:466 D-Glycitol 6:355 Glyco analogues activity 30:817 in vivo 30:817 Glycoaldehyde 25:163,164,296,314,318 Glycoalkaloid 7:427;24:132,133; 25:296,311,317-319 from potato 25:305 molluscicidal activity of 7:427 Glycobismine A 13:371,372,374,380 Glycocitrine I,II 13:338,350,357, 358,372,373 from Glycosmis citrifolia 13:348,350 Glycocyamidine 5:549 Glycocyamine 5:549 Glycoenkephalins 30:817
Glycofoline 13:348-351 from Glycosmis citrifolia 13:348-351 Glycoforms 26:1131 Glycogen 7:32 Glycogen phosphorylase 7:29,30 Glycogen phosphorylase molecule 27:821 Glycohydrolase 7:29-37,40,47,50, 58,59,65,69 Glycohydrolase lysozyme 7:31 Glycolamide 16:84 Glycolipid biosynthesis 1:417 Glycolipids 18:785-814,143;24:799 N-Glycolylneuraminic acid 18:786 Glycolysis (GADPH inhibition) 26:924 Glycookadaic acid 5:385-386,388,389 Glycopeptide 5:279;13:202 Glycopeptide antibiotics 10:657-669 Glycopeptides aeruginosin 27:205 P-Glycoprotein 22:24 Glycoprotein 5:282-285,12,457,458, 461 ;10:143,462,479;27:736;29:547; 30:841 from earthworm 30:841 Glycoprotein biosynthesis 1:417 Glycopyranoside analogs 7:14,15 Glycopyranosyl-pyrimidines 4:224 3-O-D-Glycoronide (MGGR,7) 27:6,29 ct-Glycosidase 7:59;27:256 [3-Glycosidase 7:27,28,31 Glycosidase 7:36-48,53,55-57,60,72; 8:347,351,337-403,470,471 ;10:495573,86;16:86;19:351 Glycosidase activity 28:281 ofpolyphenols 28:281 Glycosidase inhibitors 29:467 carbaaldopyranoses synthesis of 29:467 N-Glycosidation 10:595-607 oxetanocin-A synthesis by 10:595-607 with 1-O-acyl-oxetanose 10:597-604 with oxetanosyl derivative 10:595-607 with oxetanosyl halide 10:604-607
352
Glycosidation 6:276,277;24:40,41 by mycosamine 6:276,277 by silicon ether 6:262,276,277 in (-)-pseudopterosin-A synthesis 6:74,75 Noyori's 1:671,672 of 1-O-acetyl-oxetanose 10:603 of adenine 10:605 of amphoteronolide B 6:276,277 regioselective 6:262 stereochemistry of 3:197 with oxetanosyl chloride 10:605 with silver triflate/TMU 1:670, 671 [3-directing 2-bromosugars 3:202 Glycosidation-induced shift method 26:8 a-Glycoside 21:162 Glycoside 7:133,134,136 O-Glycoside 8:315;10:344,370-380 intramolecular rearrangement 10:379 stereoselective synthesis of 10:340 Glycoside B2 (forbeside B) 7:287,288,293 from Asterias amurensis 7:287 Glycoside naringin 28:288 in urine 28:288 Glycoside structural elucidation 27:484 S-Glycosides 10:380 synthesis of 10:380 C(1)-Glycosides 10:383 Glycosides 8:359-363,337-403;17:115; 21:215,241-249,258-261,457,459; 30:203 6,8-di-C-Glycosides 5:644 ~-Glycosides 8:359,361,366 H-glycosides from 3:228 Glycosides of polyhydroxysteroids 15:60-72 1,2-cis-Glycosidic bond 14:202 1,2-trans-Glycosidic bond 14:202,204 13-Glycosidic bonds 27:314 Glycosidic linkage 16:93 Glycosidic lupine alkaloid 27:268 Glycosilation effect 27:475 Glycosmic cyanocarpa 23:343
Glycosmis bilocularis 13:348,350,355 Glycosmis citrifolia 13:348,349,361 cycloglycofoline from 13:348,349 glycocitrine I from 13:348,350 glycofoline from 13:348,349,361 pyranofoline from 13:348,350 Glycosphingolipids 10:503;26:1123 biodegradation of 10:503 biosynthesis of 10:503 from denteromycetes 18:806 from zygomycetes 18:806 isolation and purification of 18:786-797 metabolism of 10:502,503 of basidiomycetes 18:806 of fungi 18:806 of Trypanosoma cruzi 18:796802 Glycosyl amines 7:44-47 Glycosyl chlorides 8:359-361 C-Glycosyl compounds 3:213-228 Glycosyl cyanide 10:358 Glycosyl fluorides 7:58,59 Glycosyl free redicals 3:221-223 Glycosyl halides substrates 7:50-59 fl-Glycosyl hydrolase 25:304 Glycosyl hydrolases 25:306,308,321 glycosylated 25:543 Glycosyl isocyanides 3:209,210 Glycosyl manganese pentacarbonyl 10:364 Glycosyl phosphates 8:83 Glycosyl phosphatidyl inositol (GPI) 23:108 Glycosyl pyridinium salts 7:57 [3-glycosidases inhibition by 7:57 glycosidases reaction with 7:5557 Glycosyl thioformimidates 10:357 from glycosyl nitriles 10:357 Glycosyl transferases 7:69 4-O-Glycosyl-2-deoxystreptamine 14:144,145 Glycosylalkynes 10:359 Glycosylated prodrug 21:161 C-Glycosylation 1:429,430,513,514 a-Glycosylation 13:217;30:457
353
1,2-cis-Glycosylation 14:209
1,2-trans-Glycosylation 14:209
O-Glycosylation 30:814 role in 6 receptor affinity 30:814 role in ~t receptor affinity 30:814 Glycosylation 6:395,397,398,400;
10:470,471,472,474-486 cis-Glycosylation procedures 14:202
Glycosylation reactions 14:201-259 Glycosylceramidase 19:352 O-Glycosyl-C-glycosylflavone 5:644 a-Glycosyl-chiro-inositol 18:434 Glycosylcobaltoxime 10:366 6-C-Glycosylflavones 5:644 Glycosylhalides 10:355 Glycosyl-O-trichloroacetimidate 14:211 7-Glycosyl-purines 4:224 Glycosyltransferase 10:115,459,461, 495-573 Glycowithanolides 20:247 from Withania somnifera 20:247 Glycoxylon huberi 15:31 2-Glyculosonates 20:857 Glycycoumarin 28:228 biological activity of 28:228 Glycycrrhizin 25:114 Glycyphylla smilax 15:31 Glycyphyllin 15:31 ;27:17,33,34 structure of 27:34 Glycyrdione A 28:228 biological activity of 28:228 Glycyrin 28:224,228,243 anti-Helicobacter pylori activity of 28:243 anti-microbial activity of 28:224 biological activity of 28:228 Glycyrol 28:224,226,241 anti-Helicobacter pylori activity of 28:241 anti-human immunodeficiency virus (HIV) activity of 28:226 anti-microbial activity of 28:224 biological activity of 28:228 Glycyrrhetic acid 7:136,138;21:642, 645,651,655 ;22:425 ;24:215264 ;25:57,59,60,65 ;28:241
anti-Helicobacter pylori activity of 28:241 from licorice 24:216 Glycyrrhetin 24:245 G 18-fl-Glycyrrhetinic acid 25:551 18a-Glycyrrhetinic acid 25:64,551; 27:858,859 18-[~-Glycyrrhetinic acid (glycyrrhetic acid) 29:586 effects on LELA 29:586 Glycyrrhiza aspera 28:204 Glycyrrhiza eurycarpa 28:204 Glycyrrhiza glabra 15:5;21:742;22:96, 422;24:151,275,919;25:465,476;26:8 00;27:6,15,29;28:204,206,234,239; 29:589 8-(?,T-dimethyallyl)-wighteone from 28:206 3 '-(?,T-dimethylallyl)-kievitone from 28:206 edudiol (3,9-dihydroxy- 1metho xy-2-prenylpterocarpan) from 28:206 euchrenone from 28:206 flavanone from 28:239 gancaonin G from 28:206 gancaonin H from 28:206 glabrene from 28:206 glabridin from 28:206 glabrone from 28:206 glisoflavanone from 28:206 glyasperin A from 28:206 glyasperin C from 28:206 glyasperin D from 28:206 glycyrrhizic acid from 28:239 glycyrrhizin from 27:6,15,29 glyinflanin G from 28:206 glyinflanin K from 28:206 hispaglabridin A from 28:206 3-hydroxyglabrol from 28:206 3-hydroxyparatocarpin C from 28:206 isoderone semilicoisoflavone I3 from 28:206 kanzonol U from 28:206 kanzonol V from 28:206 kanzonol W from 28:206 kanzonol X from 28:206
354
kanzonol Y from 28:206 kanzonol Z from 28:206 licorice-saponin G2 from 28:239 liquiritigenin from 28:239 medicarpin from 28:206 1-methoxyphaseollidin from 28:206 4'-O-methylglabridin from 28:206 shinpterocarpin from 28:206 uses as licorice 28:204 Glycyrrhiza inflata 15:26;21:740;27:15, 29,30,425;28:204 apioglycyrrhizin from 27:15,29,30 araboglycyrrhizin from 27:15, 29,30 Glycyrrhiza korshinskyi 28:204 Glycyrrhiza pallidiflora 28:234 Glycyrrhiza species 28:223,226 anti-HIV flavonoids from 28:226 bioactive phenolic compounds from 28:223 Glycyrrhiza uralensis 21:740;28:204, 234,242;29:771 4'-O-methylglabridin from 28:242 1-methoxyphaseollidin from 28:242 3-O-methylglycyrol from 28:242 6,8-diprenylorobol from 28:242 dihydroisoflavone A from 28:242 gancaonin I from 28:242 gancaonol C from 28:242 gancaonol from 28:242 glycyrin from 28:242 hispaglabridin A from 28:242 isoglycyrol from 28:242 isolicoflavonol from 28:242 licoricone from 28:242 shinflavanone from 28:242 vestitol from 28:242 Glycyrrhizic acid 21:651 ;28:241 anti-~elicobacter pylori activity of 28:241 J Glycyrrhizin 7:142,4,22,25;21:642,655, 664,675,743 ;22:136;23:316;24:151,
880-883 ;25:90,99,103,465,467; 27:5,6,15,29;29:586 as neuromuscular blocker 24:880-883 derivatives of 24:880-883 effects on thrombin interactions 29:586 hepatoprotective effect of 25:466 structure of 27:6 Glyfoline 13:375-380 antitumor activity of 13:375-380 Glyinflanin A 28:228 biological activity of 28:228 Glyoxylate carboanion 30:452 Glyoxylic acid ester 30:466 Glyphosat 25:669 Glyptopetalum sclerocarpum 30:656, 668,670
20-hdroxy-22-oxo-20-epi-
tingenone from 30:670 20-hydroxy-22-0xotingenone from 30:670 21 c~-hydroxy-20,22-dioxo30(20--->21) abeo-21desoxotingenone from 30:670 glyptopetolide from 30:656 Glyptopetolide 30:656 13C NMR spectral data of 3i):656 ~H-NMR spectrum of 30:656 HMBC spectrum of 30:656 NOESY experiment of 30:656 stereochemistry of 30:656 structure of 30:656,657 Gm ENOD 46 25:380 Gmelanone 24:785,786 biomimetic synthesis of 24:785,786 --" Gmelina arborea 17:33~2 Gnaphalin 23:614 Gnathotricus retusus 25:143 Gnathotricus sp. 25:143 Gnathotricus sulcatus 25:143 Gnetaceae spp. 27:766 Gnetifolin 20:280 Gnetin A-C 26:535,565 Gnetin E-1 26:565 Gnetum parvifolium 26:530 Gnetum ula 9:258,263 Gnidimacrin 25:543
355
Gnoderma applantum 25:131 Gobius criniger 18:48 Gogonane skeleton 25:850 Gogonian 21:312 Goiazensolide 29:89 activity in NFkB assay system 29:89 Golden hampster 5:747 Golgi mannosidase 1A 10:559 Golgi mannosidase 1B 10:559 Golgi mannosidase II 10:559 Golgi (x-mannosidase I 10:501 Gomaline 5:154 Gomberg-Batchman-Hey reaction 20:310 Gomeraldehyde (ent-8,13,epoxylabd-15-al) 25:249 Gomeric acid 25:249,268 Gomerol 25:249 Gomisin A-C 26:197,247,256-258,263, 265 Gomisin G 26:223 Gomisin J 26:197,224,247,263 Gomisin K 26:197,247 Gomisin L 26:197,247 Gomisin M 26:197,240 as PAF-induced inhibitor 26:240 Gomisin N 26:197,247,249 Gomojosidae 25:259 Gomojosides A-J 25:251 Gomophia watsoni 15:61 Gomophioside Ai9 15:61 Gonadotrophic cycle 22:376 Gonadotropin hormone 27:795 Gonadotropin-releasing harmone 27:795,796 Gonadotropins 27:796 Goniocin 18:193 Goniodiol 19:463 8-epi-Goniodiol 19:497 Goniodomin A 19:578 antifungal activity 19:578 antifungal metabolite 19:578 (+)-Goniofufurone 19:463 Goniofufurone 9:394 Goniopypyrone 9:394,19:463 Goniothalamicin 9:395 (6R)-(+)-Goniothalamin 19:479 antifungal activity of 19:479
antitumor activity of 19:479 insect antifeedant activity of 19:479 isolation of 19:481 plant growth inhibitory effect of 19:479 (R)-(+)-Goniothalamin 19:463 Goniothalamin 9:393;19:463 Goniothalamus giganteus 9:393,395; 18:221,222 ;19:498 Goniothalamus sesquipedalis 9:393 Goniothalenol (altholactone) 9:393 (+)-Goniotriol 19:464 Goniotriol 9:393,394 Gonomia kamassi 1:124 Gonorrhea 22:607,608 Gonyaulax polyedra 25:845 Gonyaulax tamarensis 17:4 Gonyauxtoxins 21:73 Gonystylus keithii 19:764 Gorgiacerone 23:173 synthesis of 23:173 Gorgonane 18:607;25:848;23:162 (+)-[3-Gorgonene 23:162 biogenetic process towards 23:163 (-)-~3-Gorgonene 6:18,27,28 Boekman-Silver synthesis of 6:18 by Robinson annulation 6:18 from maaliol 6:28 from Pseudopterogorgia americana 6:18,27 synthesis of 6:27,28 Gorgonia flabellum 9:37 23-demethylgorgosterol from 9:37 Gorgonia ventilina 9:37 23-demthylgorgosterol from 9:37 Gorgonian octacorals 23:153-184 metabolites derived from 23:153-184 plumes of 23:153-184 pseudopterogorgia species of 23:153-184 Gorgoniidae 23:153 Gorgosterol 9:35-37,45-47;21:313; 23:169
356
Goriolus versicolor 23:132 Gorman's synthesis 14:862-864 Gorytes campestris 5:251 Gorytes mystaceu 5:251 Gossypin (gossypetin 8-O-glucoside, 3,5,7,8,3',4'-hexahydroxyflavone 8O-glucoside) 29:572 Gossypium herbaceum L. 22:521; 27:855;29:579 for epilepsy 22:522 Gossypium hirsutum 26:463;29:586 Gossypium indicum 29:572 Gossypium sp. 29:581 Gossypol 13:652,659,251;25:541,543, 544;29:586 effects on acrosin, azocoll proteinase 29:586 Gosypetone reaction 5:625 GOTO cells 21:637 Gougerotin 4:241,242 Govedine 21:57 GPI bioassay 30:807,812,814 activity of k-agonist U-50,488 in 30:807 activity of glycopeptide in 30:814 activity of Tyr-(Me)2-D-Phe-GlyVal-Val-NH2 in 30:812 activity of Tyr-(Me)2-D-Phe-NH2 in 30:812 GPP 7:110,122 G-protein 30:383 effects on inositol phosphate hydrolysis 30:383 elevation of cytosolic Ca++by 30:383 inhibition of cAMP formation by 30:383 G-protein coupled-receptor 27:825; 30:383,384 association with behavioral phenotypes 30:384 G-protein-linked receptors 21:11,14; 25:530,531,539 G-proteins 18:861 Gpysophila paniculata 24:154 GR133487 (5,5-trans-fused cyclic lactone euphane triterpene) 29:586
effects on a-chymotrypsin 29:586 effects on ot-thrombin 29:586 effects on factor XIa 29:586 effects on plasmin 29:586 effects on trypsin 29:586 Gracilaria 25:769 Gracilaria coronopifolia 25:729 Gracilaria edulis 19:570 Gracilaria verrucosa 19:571 Gracillin 23:821,824 Gracula religiosa 5:837 Gradient hetero single quantum correlation 27:470 Gradient hetero multibond correlation 27:470 Grahamamycin 4:575,576 Gralactose-rich acidic glycoprotein 25:451,452 Gram positive anaerobic bacteria 21:607 Gramicidin 10:256 Gramilaurone 13:522 Graminae 9:320,328 Gramine 21:98,109;25:531 Graminone B 26:233,235 Gram-negative bacteria 16:3;21:430, 435,599,600,607,610;30:693 Maytenus species against 30:693 Gram-positive bacteria 12:48;21:186, 235,401,403,404,405,414,599,607; 23:68;30:629,693 actamycin against 23:68 Granaticin 11:213-222 2,6-dideoxyhexose moiety of 11:214,215 Grandiflorolic acid 19:389;29:100 activity in EBV bioassay system 29:100 Grandiflorolic acid angelate 29:100 activity in EBV bioassay system 29:100 Grandisin 26:198,230,799 trypanosomicidal activity of 26:230 Grandisines I,II 13:350 Grandisinine 13:350 from Citrus grandis 13:350
357 (+)-Grandisol 1:236,643,693 synthesis of 1:643,693 Grandmal seizures 22:508 Granilin 7:212,233 Granny bush 23:657 Granulaterosides A 7:299,301 Granulatoside A 15:63 Granulocyte phagocytosis 26:47,55 ofjenisseensosides C 26:47,55 ofjenisseensosides D 26:47,55 Grape fruit oil 14:449 (+)-paradisiol from 14:449 Grape stilbenoids 23:744 Grapefriut 747 Graphium sp. 5:307,309,325 Grapholitha molesta 6:557;15:384 guidongnin from 15:142,150, 159,174 Graphosoma italicum 22:387 Grasshopper ketone 6:137,143,144,158 CD correlation with 6:137 synthesis of 6:143,144 Grateloupia filicina 25:862 Gravelliferone 4:371,372 synthesis of 4:371,372 Gravimetrical methods 21:508 Grayanotoxin 1:546,547;25:242 Grayanotoxin- 1 19:397 Graynatoxin 20:17 Greanylactone 25:166 Green fluorescent protein (GFP) 25:380 Green tea 27:417,420 biological activity of 27:417,420 Green tea polyphenols 25:470 Green's procedure 6:548 Grenadadiene 25:757,771 Grevillea banskii 9:319,320 Grevillea hilliana 9:320 Grevillea pteridifolia 9:320 Grevillea pyramidalis 9:319,354 Grevillea robusta 9:320;26:1157; 27:839 extract of 27:839 Grevillea sp. 9:329 Grevillol 9:320 Griffithine 9:149,150 Grifola frondosa 5:287;23:115,124,133 Grifola umberllata 5:287,317 Grifolan 23:115
Grifolin 9:313 Grignard addition 10:147,167,180; 16:380;19:39,45,62,541 Grignard coupling 19:45 Grignard cross coupling reaction 14:575 Grignard reaction 1:261,262,533;4:330332,353,354 ;6:159,549,550;8:165, 166;9:344,345,352,527;11:81,82, 248,249;14:670;18:473,630;20:571, 589,592,595,599,600,604 Grignard reagent 4:160;19:33,35-36,38, 513,518;20:569,585,596,598;21:384; 30:30 Grindalia haverrdii 25:252 Grindelic acid 6:107 Grindella sp. 25:251 Gringerol 24:900-902;25:757 effect of general analogues on PGF2 NA- induced contraction 24:902 Gripe-bush 23:657 Griseofulvin 4:581 ;24:934;25:757 as anti-fungal agents 24:934 synthesis of 4:581 Griseogenin 7:269 Grob-type fragmentation 24:728,731 Gromphadorhina portentosa 9:488,489 Grosshemin 1:556,559-563 Grossularine- 1 5:414-417;10:245; 23:260 Grossularine-2 5:414-417;23:260 Group transfer polymerization 8:409 Growth 30:61 of tumor cells 30:61 Growth inhibition 17:142 Growth inhibitor activity 7:407, 416-419,423 ;23:297;24:859 of cyclocolorenone 24:859 of samaderines 23:297 Grubb synthesis 6:46,47 Grubbs ruthenium catalyst 30:463 Grundmann ketone 10:54,55,68,69,71 Gryllus bimaculatus 9:492;29:6 Gryllus domesticus 22:387 GST activity 21:585 GTP-binding protein 25:385 GTP-bound stimulatory G protein 25:262 Guadalupol 6:30
358
Guaiacin A,B 5:197,200 Guaiacins A-F 9:51,58,59 Guaiacol 9:467;25:126 Guaiacum officinale 5:197,139,319, 324;9:51-59 Guaiacyl subunits 25:653 Guaiacylglycerol-~-coniferyl alcohol ether diferulate 20:634 Guaiacylglycerol-13-coniferyl ether 5:464,465 Guaiacylglycerol- ~-O-6'- (2-methoxy) cinnamyl alcohol 26:211 Guaiacylglycerol-f3-O-coniferyl alcohol 27:760 polymerization of 27:760 Guaian- 1,10-epoxide 23:813 Guaian- 12,16-olides 7:214,234-236 Guaian- 12,8-olides 7:214,236 Guaiane 7:209,214,355,607;17:154 Guaiane alcohol 14:375 ' from Nardostachysjatamansi 14:375 synthesis of 14:375 trans-Guaiane sesquiterpenes 6:546,547 Guaiane skeleton 23:161 ;25:850 Guaiane system 3:44,45 synthesis of 3:44,45 Guaiane-type diterpenes 6:11 Guaiane-type sesquiterpenes 23:814 Guaianin A 5:197,198 Guaianin A2 5:197,198 Guaianin B 5:197-199 Guaianin C 5:197,199 Guaianin E 5:199,200 Guaianins A-L 9:51,52,54-58 Guaianolide 2:280,214,215,548;6:548 from (-) a-santonin 2:280,214,215,548;6:548 6,12-Guaianolides 24:806 Guaianolides 24:80-91 Guaiazulene 5:363,369 as an anti-inflammatory agent 14:315 pigments of 25:690 Guaiazulene sesquiterpenes 1:545 Guaiazulene quinone 14:315,319,321 6-(3-Guaiazulenyl)- 1(6H)guaiazulenenone 14:320
6-(3-Guaiazulenyl)-3(6H)guaiazulenone 14:328 8-(3-Guaiazulenyl)-3,7dimethylbenzofulvene-4carbaldehyde 14:343 8-(3-Guaiazulenyl)-5-(1-hydroxy- 1methyl-ethyl)-3,7-dimethyl benzofulvene 14:343 1-(3-Guaiazulenyl)-6a-isopropyl-2,5dimethyl- 1,1 a,3,6a-tetrahydrocyclopropa [f] inden-3-one 14:320 Guaiazulenylindenones 14:315 3-(3-Guaiazulenylmethyl)-8(8aH)guaiazulenone 14:344 Guainine sesquiterpenes 23:161 Guaiol 14:313 (__)-Guaiol 14:356 Guaione 25:848 Guanidine 21:254;23:343 Guanidine alkaloids 20:488 Guanidine derivatives 21:270 Guanidinoacetic acid 5:549 Guanine-cytosine 22:27 Guanosine analong 4:237 Guanosine diphosphate 22:18 Guanosine nucleotide 22:259 Guanosine triphosphate 22:33,18; 25:598 Guanyl nucleotide exchange factor 25:548 Guar 29:545 as galacto-mannan type polysaccharide 29:545 Guayabillo 22:559 Guayacasin 23:773;26:249 Guettarda platypada 17:116,125 Guggullignan-I 5:703 Guggullignan-II 5:703 Z-Guggulsterol 5:699,700 Guggulsterol-I 5:699,700 Guggulsterol-II 5:699,700 Guggulsterol-III 5:699,700 Guggulsterol-IV 5:701 Guggulsterol-V 5:701 Guggulsterol-VI 5:699,700 Guggulsterones 5:699-701 E-Guggulsterone 5:699,700 Z-Guggulsterone 5:699,700 D-lyxo-Guggultertrol-18 5:705,706
359
D-arabino-Guggultetrol $:704,706 Guggultetrol 5:705,707 synthesis of $:705,707 Guggultetrol configurations $:704,706 Guggultetrol esters $:704-709 D-ribo-Guggultetrol-18 5:704,706,708 D-xylo-Guggultetrol- 18 5:704,706,708 Guggultetrol- 18 5:710 Guggultetrol-20 $:708 D-xylo-Guggultetrol-20-ferulate $:708 Guggulu $:695-714 constituents of $:695-714 fractionation of $:697 lignans from $:703 steroidal compounds from $:698-703 steroids of 5:709-717 Guggulu steroids $:709,712 biogenesis of 5:709,712 D-xylo-Guggulutetrol-18 ferulate $:708 Gugulipid $:715,716 Guiaflavine 26:1055,1056 Guianensine 26:1055,1056 Guianin 8:159 synthesis of 8:159 Guidimacrin 27:831 antitumor mechanism of 27:831 Guillain-Barre syndrome 22:584 Guinea-pig ileum bioassay 30:802 activity of ~t-opioid receptor in 30:802 in vitro 30:802 L-Gulonolactone 7:12 6-epi-castanospermine from 7:12 1,6-di-epi-castanospermine from 7:12 L-Gulopyranose analogs 6:373-375 Gum japonica 29:575 Gum mesquite 29:546 as acidic polysaccharide 29:546 chemical structure of 29:309,310 from mesquite tree 29:546 Gum resin $:700 Gundelia toumefortii 7:427 Gurjar's syntheses 30:33-37 of (-)-pironetin 30:33-37 or 23:535,549 Gurmarin 27:42 as sweetness inhibitor
Gutierrezia grandis 5:680;25:251 Gutierrezia microcephala 5:680,681 Gutierrezia spathulata 25:251 Gutierrezia sphacrocephala 25:251 Gutierrezia texana $:679 Gutierrezia-xanthocephahum 5:676 Guttiferae 7:409-411,417,418,420-423, 19:768;22:646,650,654,661,662 Guttiferone A 22:659 Guvacine 21:84 Gycolic acid 16:84 Gyminda 18:741 Gymnema alternifolium 27:41,43,44 alternoside I-V from 27:41 Gymnema sylvestre 15:36;18:649,650, 653,661,671,673 ;21:666,674 ;23:519; 27:40-43,48,49 gymnemasoponin III,IV,V from 27:41 gynmemic acid II-VI,VIII-XVIII from 27:41 Gymnemagenin 18:649,650;27:42,44 structure of 27:44 Gymnemanol 18:650,665 Gymnemasaponins III-V 27:41,43 as sweetness inhibitors 27:41 Gymnemasides 18:650 Gymnemic acid I-VI,VIII,XVIII 27:41, 43,44 as sweetness inhibitors 27:41 structures of 27:44 Gymnemic acid V 21:667 Gymnemic acid VII 21:666 Gymnemic acids 18:649-676 biological activity of 18:670-674 from Gymnema ~ylvestre 18:649-676 biological activity of 18:670-674 Gyrnnemoside b 21:666 Gymnestrogenin 18:649,650,656 from Gymnema sylvestre 18:649,650,656 Gymnestrogenin-type aglycone 27:47 structure of 27:47 Gymnochromes A-D 15:105-107 Gymnocladus chinensis 21:643 saponin D from 21:643 Gymnocladussaponin G 21:643,664 Gymnocolea inflata 2:280
360
Gymnocrinus richeri 15:105;28:719
gymnochrome C from 28:719 Gymnodinium 25:864 Gymnodinium breve 17:20;19:430; 21:300,301 Gymnolaemata 17:106 Gymnomitrion obtusum 13:39 Gymnomitrol 13:39-41 Gymnosperma glutinosum 5:679-681 Gymnospermae 9:317,321,323 Gymnosporia montana 23:656 Gymnotroches axillaris 7:192 Gynandropsis gynandra (L.) 28:395,405 repellent properties of 28:395 Gynandropsis pentaphylla 22:522 for convulsions 22:522 Gynostemma pentaphyllum 18:662; 21:675;24:144;27:15,28 gypenoside XX from 27:15 Gypenosides 18:650;21:675 Gypsogenic acid 24:151-153;26:29,36 mimonosides Ma from 24:151, 152 mimonosides Mb from 24:151, 152 mimonosides Mc from 24:151, 152 Gypsogenin 17:121 Gypsophila 26:55 of adjuvant activity 26:55 Gypsophila arrostii 26:38,39,40 Gypsophila bermejoi 26:44,52 Gypsophila capillaris 26:42,43 Gypsophila capitala 26:44 Gypsophilafastigiata 26:38 Gypsophila oldhamiana 26:41 Gypsophila paniculata 26:38-40,42,53 hemolytic activity of 26:41 spermicidal activity of 26:53 Gypsophila perfoliata 26:38 Gypsophila saponins 26:55 immunomodulatory effect of 55 Gypsophila sp. 24:131,144,149, ,155,161;26:55 Gypsophiloides 26:3 Gypsy moth 24:865 bioassay of 24:865 Gyrocarpine 26:824,826
Gyrocarpus americanus Jacq. 22:552 for epilepsy 22:522
Gyrophora aureolum 6:135 Gyrophora esculenta 5:311,322;23:123 Gyrostroma missouriense 15:351,383
nectriapyrone from 21:207 Gyroxanthal 6:162,163 Gyroxanthin 6:162-164
1H-NMR data 23:599-634;26:321,324, 326,329;538,539,540,541,542,543 of (+)-e-viniferin 26:540 of lO-epi-teuclatriol 23:635 of 11-hydroxy-valenc 1(10)-en-2one 23:635 of 12-epi-teucvidin 23:601 of 2-deoxychamaedroxide 23:609,610 of 3~-H-neo-clerodanes 23:607 of3-deacetylalysine B 23:634 of6-deacetylsandrasin A 23:624 of 7-epi-eudesm-4(15)-ene-1[3, 6c~-diol 23:635 of 7-epi-eudesm-4(15)-ene-1D, 613-diol 23:635 ofalysine B 23:634 ofalysine D 23:634 ofalysine E 23:634 ofampelopsin A 26:538 ofampelopsin D 26:538 ofampelopsin F 26:538 ofanigopreissin A 26:538 of balanocarpol 26:539 ofbetulifol A 26:539 ofbetulifol B 26:539 of bidentatin 23:609 of corilagin 23:426 ofcyphostemmin A 26:539 ofcyphostemmin B 26:540 of ellagitannin oligomers 23:426 of e-viniferin diol 26:540 of geraniin 23:426 of gnaphalin 23:614 ofgnetin A 26:540 of gnetin BV 26:541 of gnetin C 26:541 of gnetin F 26:541
361
of gnetin G 26:541 of hydroxyframoside A&B 26:326 ofhydroxyomoside 26:321 ofinsularoside 26:321 of isolugrandosidc acetate 26:329 of isolugrandoside 26:329 of isostrictinin 23:426 ofleachinol G 26:542 ofmalibatol A 26:542 of montanin H 23:617 of neo-clerodanes 23:601 ofnupharin A 23:426 ofparthenocissin A 26:542 ofplectrinone A 23:630 of potentillin 23:426 ofpraecoxin B 23:426 ofrestrytisol A 26:541 ofrestrytisol B 26:543 ofrestrytisol C 26:543 ofsandrasin A 23:624,625 ofsandrasin B 23:625 of strictinin 23:426 of tellimagarandin I 23:426 oftellimagarandin II 23:426 of teuchamaedrin C 23:618,619 of teucladiol 23:635 of teuclatriol 23:635 ofteucrolivin A 23:627 ofteucrolivin F 23:627 of teucvidin 23:597,599 of teucvin 23:597,599 of teuflidin 23:597,599 of teuflin 23:596,599 ofteugnaphalodin 23:619 ofteupernin A 23:607,610 of teupernin B 23:610 of teupyrin A 23:619 of teuvlncenone A 23:630 of teuvlncenone B 23:630 of teuvlncenone C 23:630 of teuvlncenone D 23:630 of teuvlncenone E 23:630 of teuvlncenone F 23:630 of teuvlncenone G 23:630 of teuvmcenone H 23:630 of teuvlncenone I 23:630 of tricuspidatol A 26:543
of vaticaffinol 23:544 of vescalagin 23:426 ofvillosin A 23:632 ofvillosin B 23:632 ofvillosin C 23:632 of viniferifuran 26:543 H +, K+-ATPase 25:613 H+/K+-ATPase inhibitor 25:612;28:676 hexaprenyl-hydroquinone sulfate as 28:676 ~H homonuclear correlation spectroscopy (COSY) 30:584 ofherveline A 30:583 IH-IH COSY 30:587 of (-)-hernone 30:587 (-)-6'-hydroxyyatein 30:587 ~H-NMR assignments 23:29 ofAc-SAMM 2 23:29 of BZSAM 23:44 ofBZSAMM 1 23:44 of ~H-NMR assignments of 23:44 of SAM 23:29 of SAM MM 1 23:29 ofSAMM 1 23:29 1H-NMR chemical shifts 23:499-507 ofbacopasaponin A 23:504 ofbacopasaponin B 506 ofbacopasaponin C 23:507 IH-NMR spectra 27:339 of abscisic acid in acetone-d6 27:339 ~H-NMR spectrum 21:733,745;27:176, 350;30:570,581-584,586,587 of (7R,8S,7'R,8'R)-(+)-7'-acetyl5 '-methoxypicropodophyllin 30:586 of (-)-6'-hydroxyyatein 30:587 of (-)-hernone 30:587 of (+)-malekulatine 30:584 of (+)-N-formylovigerine 30:582 of 7-formyldehydroovigerine 30:581 of chelerythrine free base 27:176 of demethylsonodione 30:570 of ernamymphine 30:582 ofherveline A 30:583 ofphaseic acid 27:350
362
tH-NMR studies 27:338 of abscisic acid 27:338 HIV inhibitors 25:942 H2 receptors 25:612 H202-induced apoptosis 25:269 HA 26:1002-1004 antibacterial activity of 26:1002 as a carcinogen 26:1002-1004 HA inhibitors 27:116-129 2 ~-chlori-peracetyl-Neu methyl ester 27:124,127 4-(8-morpholin) capriloylNeu5Ac-~x2Me 27:126,127 4,7-di-O-acetyl-Neu5 Ac-cz2Me 27:123 4-capriloyl-Neu5 Ac-cz2Me 27:125-127 4-O-acetyl-Neu5 Ac-cz2Me 27:123 4-O-capriloyl-Neu5 Ac-2Me 27:125 4-O-phenyl-2-propionylNeu5Ac-cz2Me 27:123 4-t-butyl-dimethyl-silyl ether 27:127 5-azido-5-deamino-Neu5Accz2Me 27:119 5-N-benzyloxycarbonyl-Neuot2Me 27:119 5-N-propionyl-Neu-cz2Me 27:119 7-deoxy-Neu5 Ac-(x2Me 27:123,127 8-amino-8-deoxy-Neu5Ac 27:121,122 8-azido-8-deoxy-Neu5Ac 27:121,122 8-tosyl-Neu5AcMe ester 27:121,122 9-amino-9-deoxy-Neu5 Ac 27:121,122 9-amino-9-deoxy-Neu5Ac-cz2Me 27:119 9-azido-9-deoxy-Neu5 Ac 27:121,22 9-azido-9-deoxy-Neu5 Ac-cx2Me 27:119 9-O-acetyl-Neu5 Ac-ot2Me
27:119 9-tosyl-Neu5AcMe ester 27:121,122 Neu 5Ac methyl ester 27:120-122 Neu5Ac-cz2Me 27:119-121 Neu5Ac-(x2Me amide 27:119, 120 Neu5Ac-cz2Me benzyl ester 27:125-127 Neu5Ac-o~2Me methyl ester 27:125-127 Neu5Ac-[32Me methyl ester 313 27:125,127 peracetyl-Neu-cz2Me acid methyl ester 27:124,127 Haageanolide 8:195-201 Haber-Weiss reaction 22:327,435; 26:975 Hacelia attenuata 7:290,295,304-306; 15:61 (+)-Haedoxan A 26:231,232 (+)-Haedoxan B 26:231,232 (-)-Haedoxan D 26:231 (+)-Haedoxan D 26:231 Haemagglutinin (HA) 16:93,102; 27:103,107 for influenza infection 27:103 inhibitors of 27:117-129 Haemagglutinin-based inhibitors 16:111 Haemanthamine 20:325,353,356,369, 383 Haemanthidine 20:352 Haemaphysalis intermedia 28:400 Haematococcus pluvialis 21:305 Haematoxylin 15:34,20:781,782-784 Haematoxylon campechainum 15:34, 20:776;27:18 hematoxylin from 27:18 Haemodoraceae 17:372 Haemolymph 22:374,382,391 Haemolytic activity 23:512 of saikosaponins 23:512 Haemonchus 26:425 Haemonchus contortus 22:401 ;25:794; 26:429,431,432,440,446,451,453,45 7,470,482,484,488,490,491 ;28:342, 349
363
Haemophilus influenzae 4:195 ;25:781 Haemopoietic stem cells 30:766 Haemorrhagic fever virus (CCHFV) 30:410 Hairy root cultures 17:426 Hakamori method 2:336;15:192 Hakamori permethylation 5:199 Hakea 26:1157 Hakea amplexicaulis 9:320 tlakea gibbosa 29:576 Hakea persihana 9:320 Hakea trifurcata 9:320 Hakomori's procedure 27:512 Halcyon smyrnensis 5:837 Halenaquinol 6:4;25:694 Halenaquinol dimethyl ether 17:40 Halenaquinol sulfate 28:677 absolute stereochemistry of 28:677 as pentacyclic hydroquinone 28:677 as yellow pigment 28:677 Halenaquinone 17:33;25:861 (+)-Halenequinol 17:48-50,55-61 (+)-Halenequinone 17:48-50,55-61 Haliangolides 7:210,211 Haliangolidin 7:230 Halicerebroside A 18:459 Halichlorine 25:799 Halichondria 27:875;28:658 Halichondria cf. moorei 28:698 Halichondria cylindrata 23:341 ;28:139, 680 Halichondriajaponica 18:475;25:718 Halichondria melanodocia 5:387 Halichondria okadai 5:378,379,383, 384;21:411;25:799 Halichondria panicea 17:719;25:852; 28:661 Halichondria sp. 17:17;21:329,330; 25:716,847,848,852,854 ;28:659,660 diterpenoid from 28:659 from Marshall islands 28:660 guai-6-ene skeleton of 28:660 sesqui- and diterpenoids from 28:659 Halichondria sponge 21:252;28:663 isothiocyanates from 28:663 Halichondrida order 28:658
Halichondride antitumor activity of 5:378,380 Halichondriidae 28:671 Halichondrin 25:728 Halichondrin I3 25:727 Halichondrins B,C 5:377-382 Haliclona exigua 21:267 Haliclona nigra 28:684 from Papua New Guinea 28:684 haligramides A of 28:684 Haliclona rubens 21:308 Haliclona sp. 5:346,347,459,706; 21:260,674 ;25:694,695,709,710,725, 728;28:706 haliclostanone sulfate from 28:706 Haliclonacyclamines 25:710 Haliclonadiamine 24:573,650,659 Halicona kormella 25:722 Halicona oxigua 25:732 Halicyclamine A 21:308 Halicylindramide A 23:341;25:867; 28:680 as antifungal substance 28:680 as cytotoxic substance 28:680 Halicylindramide B 23:341 ;25:867; 28:680 as antifungal substance 28:680 as cytotoxic substance 28:680 Halicylindramide C 23:341 ;25:865,867; 28:680 as antifungal substance 28:680 as cytotoxic substance 28:680 Halicylindramides E 25:866,867 Halimeda incrassata 18:689 Halimeda tuna 689 Haliotis discus hannai 25:788 (-)-Halipanicine 25:852 Halipanicine 28:661 total synthesis of 28:661 Halistanol disulfate B 25:704;28:699 in endothelin converting enzyme (ECE) assay 28:699 Halistanol sulfate 28:698 antimicrobial activity of 28:698 hemolytic activity of 28:698 ichthyotoxic activity of 28:698 pp60v-src protein tyrosine kinase inhibition activity 28:698
364 Halistanol trisulphate 25:704;27:861 Halisulphate 25:263,799 derivative 25:699 Halitunal 16:302 antiviral activity of 16:302 Halityle regularis 7:297;15:61 halityloside D and I from 15:61 gomophioside A from 15:61 halitylosides A,B,D,E,F,H,I from 7:297 Halityloside A, I 15:61 from Halityle regularis 15:61 Halitylosides A,B,D,E,F,H,I 7:298 from Halityle regularis 7:297 from Nordoa gomophia 7:298 from Nordona novaecaledonia 7:298 from Sphaerodiscus placenta 7:298 Hallerone 16:616 Hallucinogenic agent 21:101 w-Halo-acids 8:239 (c~-Haloalkyl) (alkyl) boronic ester 11:409 (c~-Haloalkyl) boronic ester 11:409,410 amino acids from 11:417-420 carbohydrates from 11:420-422 from alkenyl boronic esters 11:409,410 synthesis of 11:409,410 Haloamidation 14:568 Halobacterium sp. 7:355 bacterioruberin from 7:355 Halocyamine A 23:243 Halocyamine B 23:243 Halocynthia papillosa 28:642 6-methylheptyl sulfate from 28:642 (E)-oct-5-enyl sulfate from 28:642 Halocynthia roretzi 6:152;23:243; 25:704,784 ;28:642 halocynthiaxanthin from 6:152 mytiloxanthinone from 6:152 Halocynthiaxanthin 6:142,143,152 from Halocynthia roretzi 6:152 et-Haloester 11:117 dioxoester from 11:117
Halofantrine 20:516;22:148 Halogenated analogues 12:398 Halogenated cyclic peptides 23:341 Halogenated quinones 4:331,332 coupling of 4:331,332 Halogenation 27:749,752 of olefins 27:749,752 Halogen-containing antibiotics 29:309 biological effects of 29:309 chemical structure of 29:309,310 chloramphenicol as 29:309 chlorinated derivatives as 29:309 fluoroacetate as 29:310 4-fluorothreonine as 29:310 from Streptomyces venezuelae 29:309 from streptomycetes 29:309 in aquatic organisms 29:309 in terrestrial organisms 29:309 isolation of 29:309 occurrence of 29:309 Halogene-nucleophile 19:438 Halogen-free malyngamide J 25:788 (E)-13-Halogenoacrylamides 21:381 1-Halogenobenzyl isoquinoline derivatives 6:482 dibenz [d,f] azonine derivatives from 6:482 Halohydrin formation 11:141 2-deoxy-l-hydroxy sugars from 11:141 Halolactonizations 1:627-629 of cycloalkene ketals 1:627-629 a-Halomethylcycloheptanone 8:35,36 synthesis of 8:35,36 c~-Halomethyltetrahydroeucarvones 8:36 Halomicin 23:54 Halomon 25:702 Halopappus parvifolus 25:255 Halopappus sp. 25:251 Haloperoxidase 25:758 Halophilic bacteria 30:520 Halophylidin 22:522,539 Halopuupehenones 6:26:233 from Heteronema 6:26:233 synthesis of 6:23,24
365
Halotyrosine-derived metabolites 21:307 Halymenia porphyroides 9:85,86,88 marine N-acylsphingosine from 9:85,86,88 Halyminine 9:85,86,88 Hamamelis virginiana 21:543;29:588 (+)-Hamatine 20:422-424 Hamigera tarangaensis 25:803 Hamigeran B 25:803 Haminaea templadoi 26:90 Hamioea cymbalum 25:787 Hamster assay 21:671 Hamster fetus 23:570 encephalocele in 23:570 Hamycin 26:794,795 Hanacantha sp. 25:705 Hanalpinol 23:813,814 Hanalpinone 814 Hanamyol 23:813 Hanessian reaction 1:511,512 Hanessian's deconj ugation-epimerization 12:13 of avermectin Bla derivatives 12:13 Hanessian's epimerization 12:28 macrocyclization with 12:28 Hanessian's procedure 12:347 from debenzylidenation 12:347 Hanessian's synthesis 12:12-15 ofavermeetin Bla 12:12-15 Hanfillin 27:564 Hanging drop vapor-diffusion technique 30:831 of EFEa 30:831 Hannoa klaineana 18:726;23:302 Hannoa quassiaundulata 26:466 Hannokinin 17:360 Hannokinol 17:360 Hanphyllin 7:230 Hanseniaspora osmophila 5:283 Hansenula beijerinkii 5:287 Hansenula bimundalis var. americana 5:287 Hansenula capsulata 5:280,284,315 Hansenula ciferii 5:287 Hansenula fabianii 5:287 Hansenula minuta 5:315 Hansenula mrakii 5:287;25:129
Hansenula polymorpha 22:601; 26:1263,1267,1270,1272,1274
Hansenula saturnus 5:287 Hansenula sp. 5:281,282,315 ;26:1087 mannans from 5:282
Hansenula subpelliculosa 5:282 Hansenula wingei 5:282 Hansfordia pulvinata 6:413-415 IH, laC-NMR of analogs 6:413-415 of MurNAc 6:413-415 Hantzsch synthesis 4:86 racemization during 4:86 Hapalindole A 21:362;26:363 (+)-Hapalindole Q 16:131 Hapalindoles 11:278 from Hapalosiphon fontinalis 11:278 Hapalochlaena maculosa 18:724 Hapalopilus nidulans 29:265 Hapalopilus rutilans 29:265 Hapalosin 25:714 Hapalosiphon fontinalis 11:278;21:362; 26:363 hapalindoles from 11:278 Hapalosiphon intricatus 26:363 Hapatocyte necrosis 25:462 Hapatotoxins 25:461 Haplopappus 29:577 Haplopappus canescens 29:577,580, 581 Haplophyllum dauricum 17:335 Haplophyllum dubium 22:522 Haplophyllum glabruinum 22:522 Haplophyllum hispanicum 26:263 diphyllin acetyl apioside from 26:263 tuberculatin from 26:263 Haplophyllum perforatum 22:522 Haplosamate A 25:898;28:703 as HIV- 1 integrase inhibitor 28:703 Haplosamate B 25:898 Happlopappus arbutoides 25:251 Happlopappus pulchellus 25:251 Hapten-carrier protein conjugated 25:434 Harappamine 2:176,177 Hard acids/bases 3:409
366
Hardwickiic acid 30:710,711 structure of 30:710,711 Harmaline 5:190;21:68,89,96,97,102, 108,109;22:24,36;25:533,537; 26:828,829 as immunosuppressive drug 25:537 tautomerism of 5:190 Harman 5:353;18:726;26:828,829 from Costaticella hastata 18:726 Harmine 21:68,80,96,97,102,108;22:28; 25:533,537 as immunosuppressive drug 25:537 Harpagide 7:455,459,460-466,477; 29:83 activity in EBV assay system 29:83 Harringtonine 21:97 Harzianic acid 21:216;28:135 antibiotic activity of 28:136 Harzianopyridone 21:213,214 Haslinger and Michel synthesis 14:689-692 of taxodione 14:689-692 Hasnenula holstii 5:280,285,315 Hastanecine 1:245,246,252,253 synthesis of 1:245,246,252,253 (+)-Hastanecine 12:472 Hastatoside 7:455 Hatanecine 3:54 Hatch-Slack metabolism 13:330 Haticondria cylindrata 25:867 Hatistanol sulfates 25:703 Hattalin 26:216,269 ouabain receptor 26:216 Hazimycin 21:362 Hazuntine 9:193 Hazuntinine 5:124 Hazuntiphylline 5:129 HBsAg 21:648;20:533 HBsAg secretion 20:539 HBV 30:406 immunization against 30:406 HBV infection 20:528-530 HBV infectivity 30:406 HCMV 21:665,666 HCT 15(cdon) 22:621
H-Dmt-Tic-Ala-OH (DTA) 30:804 as 5-opioid receptor antagonist 30:804 H-D-Phe-c-(Cys-Tyr-D-Trp-Arg-ThrPen)Thr-NH2 30:813 from somatostatin 30:813 Headache 30:192 use of non-steroidal antiinflammatory drugs (N SAIDs) 30:192 use of prostaglandin inhibitors 30:192 Head-to-tail polymerization 27:774 Healing properties 22:361 of 3',4-O-dimethylcedrusin 22:361 Heamanthidine 4:3,4 from amaryllidaceae 4:3,4 pretazettine from 4:17 synthesis of 4:17-20 Heart diseases 30:55 role of natural products in 30:55 Heart rate 26:183 effect of Schisandra on 26:183 Heartworm 1:435 Heat-activated channel TRPVI 30:193 type of ionotropic receptor 30:193 Heathcock's asymmetric aldol reaction 18:283 Heat-inactivated proteases 25:439 Hebesterol 9:43 biosynthesis of 9:43 from Petrosia hebes 9:37 Heck arylation 19:274,19:277 Heck coupling 19:276 Heck reaction 16:367,391,400,412,416, 418,427,429,430,432,435,438,439, 447;18:96;19:22,78,279,284 asymmetric 19:22 intramolecular 16:429,430,438, 439 of olefin 19:279 palladium-catalyzed 19:78 Pd(0) catalyzed 16:439 silver modifaction of 16:429 with 1-octen-3-one 16:391 Heck reaction conditions 19:227,279
367 Heck vinylation 16:432 intramolecular 16:432 Hecubine 5:172 Hedamycin 11:136 Hedeoma pulegioides L. 22:522 for convulsions and spasms 22:522 Hedera helix 7:427,20:6;21:642,662, 674 ;24:132,133 ;26:813 ;29:586 Hederagenin 7:134,135,429,431-433, 9:61,62;21:656,665 ;22:97;25:60 molluscicidal activity of 7:432 Hederagenin (triterpene) 29:586 effects on LELA 29:586 Hederagenin monodesmosides 30.'203, 204 agglutination inhibition by 30:204 anti-rheumatoidal effect of 30:204 edema inhibition by 30:204 effect on trypsin activity 30:204 kalopanaxsaponins-A 30:203 kalopanaxsaponins-I 30:203 trypsin production inhibition by 30:204 use in chronic rheumatoidal arthritis 30:204 vascular permeability inhibition by 30:204 Hederagin 26:814 c~-Hederin 21:642,656;20:6;26:814 [3-Hederin 20:6;26:814 Hedychenone 23:838 Hedychium 23:837 Hedychium coronarium 23:836;24:284; 25:265 Hedychium flavum 27:377 Heimerlein 27:564 Heinsia crinata 151 Heinsiagenin A,B 10:151 Heisteria pallida 22:360 HeLa 25:301 cells 25:268 HeLa 229 cells 21:718 HeLa assay 25:45 HeLa cells inhibition 25:45,46 HeLa $3 cells 21:263;25:790 Heldrichinic acid 20:670 from Salvia napifolia 20:670
Helenalin 20:10;29:90 activity in CRG assay system 29:90 activity in NFkB assay system 29:90 Helenalin acetate 29:90 activity in NFAT assay system 29:90 activity in NFkB assay system 29:90 Helenalin isobutyrate 29:90 activity in NFAT assay system 29:90 activity in NFkB assay system 29:90 Helenalin tigulinate 29:90 activity in NFAT assay system 29:90 activity in NFkB assay system 29:90 Helenanes 16:664 antiinflammatory activity of 16:664 antileukemic activity of 16:664 cyctotoxic activity of 16:664 Helenanolide 16:133 synthesis of 16:133 Helenanolide intermediate 4:674 Helenium 26:436 Helenium amarum 20:10 Helenium microce 20:10 Heliangolides 24:806 Helianthus 29:589 Helianthus annuus 19:247;21:634,660; 25:391,670;29:593,600 Heliantriol C 25:57,62 Heliantriol C (taraxast-20-ene-3~,1613, 22c~-triol) 29:587 effects on CHY 29:587 Heliantriol C 3-O-myristate (taraxast20-ene-3[~,16~,22~-triol 3-0myristate) 29:587 effects on TRY 29:587 Heliantroil Bo 22:122 Heliantroil B2 22:122 Heliantroil C 22:122 Heliantrol B2 25:57 Helicacus kanaloanus 15:383
368
Helichrysum gymnocephalum 27:377 Helichrysum nitens 5:413 antifungal flavonoids from 5:651
Helichrysum picardii 29:702 Helichrysum rupestre 25:259 Helichrysum setosum 22:522
for epilepsy 22:522 Helicity rules 2:164,165 Helicobacter pylori 13:183;22:432; 25:611,617,618,778;26:693;30:338 Helicobacter pylori inhibition 30:338 by chrysophanol 30:338 by emodin 30:338 by rhein 30:338 Helicondria sp. 9:37 petrosterol from 9:37 Heliconius pachinus 8:222 macrolide from 8:222 Helicostylium piriforme 25:317 Helicoverpa zea 26:697;29:292 Helicteres isora 26:226 helisorin from 26:226 helisterculin A&B from 26:226 Heliettin 22:517,538 Heliocidaris erythrogramma 17:95 Heliocide B 4:618,619 biosynthesis of 4:618,619 Helioporuns A-E 25:690 Heliopsis buphthalmoides 17:319 Heliopsis helianthoide 5:334,728 hemoglobin components of 5:836-839 in bird species 5:836-839 Heliopsis longipes 7:427;24:689 Heliothis armigera 23:66;26:850,851 Heliothis virescens 7:395;21:252; 25:768;26:439,485 Heliotridane 1:54,239,243,256,258 synthesis of 1:54,239,243,256, 258 (+)-Heliotridane 16:444 synthesis of 16:444 Heliotridine 1:231,232,246 synthesis of 1:231,232,246 (+)-Heliotridine 12:472-474 synthesis of 12:472-474 Heliotrine 1:267,268 synthesis of 1:267,268 Heliotropium bovei 26:874
Heliotropium floridum 26:874 Heliotropium megalantum 26:874 Heliotropium sinuatum 26:874 Heliotropium sp. 26:872 Heliotropium strygosum 19:145 Helioxanthin 17:334;26:194,232 synthesis of 17:334 Helisorin 26:226 Helisterculin A&B 26:226 Helix promatia 18:655;19:636;25:210; 27:468 Helleborus purpurescens 21:657 Helmchen's camphor 8:416 Helmindiol 26:451 (+)-Helminthosporal 16:265 synthesis of 16:265 Helminthosporal 8:162,163 Helminthosporin teres 2:434 Helrninthosporium 25:828 Helminthosporium carbonum 22:459; 27:498,499 Helminthosporium gramieu 26:1210 Helminthosporium oryzae 9:237 Helminthosporium sativum 4:23,24,192 Helminthosporium sigmoideum 22:273 Helvella gyomitra 9:203 Hemacytometer 9:232 Hemagglutinins 24:478-483,484 assay 24:483-480 Hemandezine 21:79 Hemangiomas 26:693 Hemanthamine 21:97 [3-Hematin 25:343 fl-Hematin aggregation 25:342,354 inhibition of 25:342,354 Hematologic toxicity 27:436;28:559 with immunosuppression 28:559 with leukopenia 28:559 Hematopoietic cancer cells apoptosis 26:925 Hematoporetic stem cell 27:806 Hematoporphyrin 25:354 Hematoporphyrin IX 25:355 (+)-Hematoxylin 27:18,37,38 structure of 27:38 Heme aggregation 25:329,343,349,351, 352,353,355,356 Heme aggregation activity 25:341
369
Heme aggregation assays 25:348,352, 354 Heme aggregation efficacy 25:355 Heme aggregation inhibitor 25:327,329, 343,352,359 Heme detoxification 25:329,331 Heme polymerase 25:30,333 Heme polymerization 25:334,348 inhibition of 25:348 Heme polymerization assay 25:334,354 Heme polymerization inhibitor 25:327, 343,347,348 Heme polymerization inhibitory activity 25:345 Heme proteolysis 25:331 Heme sequestration 25:348 inhibition of 25:384 13-Hemetin 25:31,38,332,333,340,356, 357,358,360 inhibitor of 25:357 [3-Hemetin aggregation 25:357 [3-Hemetin assay 25:355 11,15-Hemiacetal 25:266 Hemiacetal 7:465 Hemiacetal ethers 27:189 retrosynthetic analysis of 27:189 Hemiacetal isomers 21:143 Hemiacetal moiety 30:450 reduction of 30:450 ozonolysis process 30:450 Hemiacetalization reaction 30:437 Hemibiotrophic tomato pathogen 25:302,308 Hemicellulose 7:195 Hemicentrotus pulcherrimus 26:1188; 28:717;29:268 Hemicryptophyte plant 27:663 Hemidesmus indicus R. 22:522 for epilepsy and nocturnal epilepsy 22:522 Hemimetabolous 22:376 Hemin 25:337 Heminitidulan 4:391,392 synthesis of 4:391,392 Hemiptera 22:398 Hemisphere rule 2:165 Hemi-synthesis 18:219,220 of acetogenins 18:219-222 of solamin 18:219,220
of reticulatacin 18:219,220 of corrossolone 18:220,221 of isodeacetyl uvariein 18:221 of gigantccin 18:221,222 Hemodynamic changes 23:12 Hemoglobin 30:59,60,65-67,69 carp oil effects on 30:66 effect of oleic acid on 30:65 effects of triterpenoid fractions on 59 oleic acid effects on 30:67 Hemoglobin proteolytic enzyme 25:360 Hemoglobin/HA interactions 26:985-987 Hemoglobinase 25:330 Hemolysins 9:317 Hemolysis 25:180,464 Hemolytic activity 21:660,661;26:41, 42;28:698 of Gypsophila paniculata 26:41 ofhalistanol sulfate 28:698 of SAPO 30 26:41 of SAPO 50 26:4I Hemophilus influenzae 13:162,177,181 Hemorrhage complication 30:839 Hemorrhage-inducing activity 23:139 Hemosiderin 22:327 Hemostatic process 30:593 role of platelets in 30:593 Hemozoin 25:354 inhibition of 25:354 Hemozoin aggregation 25:334,337 Hemozoin aggregation inhibition 25:342 Hemozoin inhibition 25:341,342,356 Hemozoin inhibitor drugs 25:360 Hemozoin nucleation 25:334 Hemozoins composition 25:338 Hemsleya carnosiflora 24:249;27:14; 29:53 carnosifloside V from 27:14 carnosifloside VI from 27:14 Hemsleya panacisscandens 24:249; 27:15,25 scandenoside R6 from 27:15,25 scandenoside R11 from 27:15,25 (Z)-Heneicos-6-en-11-one 19:124,126 sex pheromone of 19:124,126 (Z)-4-Heneicosenal 26:81
370
Henricia laeviuscola 15:48,55;28:718 henricioside from 15:48,55 Henricioside A 15:48 from Henricia laeviuscola 15:48 Henry condensation 1:408,409 Henry reaction 19:120,165,173 pyperidine-catalyzed 19:165 Henrycine A 15:115,122,129,171,172 13C-NMR of 15:129 from Rabdosia flexicaulis 15:171 from Rabdosia henryi 15:172 ~H-NMR of 15:122 Henryin (reniformin A) 15:172 J3C-NMR of 15:131 from Rabdosia henryi 15:172 from Rabdosia latifolia var. reniformis 15:172 lH-NMR of 15:124 Hep-2 (human carcinoma of larynx) 30:692 Heparanase activity 16:90 in malignant cells 16:90 Heparin 30:58,397,404 against pseudorabies virus 30:404 in HIV therapy 30:397 Heparin derivatives 30:399 anticoagulant activity of 30:399 Hepatic activity 26:253 Hepatic apoptosis 25:468 Hepatic DNA fragmentation 25:466, 467,468,469,472 Hepatic information 25:479 Hepatic intoxication 25:466 with D-Gal N 25:466 with LPS 25:466 Hepatic mRNA induction 25:468 Hepatic total cholesterol concentration 30:93 effects of Platycodi radix on 30:93 Hepatic triacylglycerol 30:81,93 accumulation of 30:93 effect of high-fat diet on 30:93 Hepatic triyglyceride 30:81 Hepaticae 2:277;9:249 Hepatitis 26:183;30:207 effect of Schisandra in 26:183
treatment of 30:207 use of Phyllanthus (genus) in 207 Hepatitis A virus 30:406 Hepatitis A 21:662 Hepatitis B 21:662 Hepatitis C 21:662 Hepatitis B capsid 30:406 Hepatitis B surface antigen 20:537 Hepatitis B virus 20:227,528;21:648, 656;25:114 Hepatitis D agent 30:406 Hepatitis-B surface antigen 30:840 bromelain 30:840 Hepatocarcinogenesis 26:257 Hepatocellular uridine phosphate UDP and UTP 25:461 Hepatocyte apoptosis 25:459,460,462, 464,468,469 Hepatocyte necrosis 25:466,468,476 Hepatocytes 23:14 Hepatoma cell 27:806 Hepatoma cell line PLC/PRF/5 30:406 Hepatopretective agent 22:358 ursolic acid as 22:358 Hepatoprotective agent 22:346,358; 23:753;25:462,465 Achyrocline satureioides as 22:346 ursolic acid as 22:358 Hepatoprotective activity 20:116; 25:90,103,106,467,469,474 ;26:255, 257 ;28:257,293 ;30:291 ofbaicalein 30:291 ofbaicalin 30:291 of bupleuroside III,IV,XIII 25:474 of Curcumia longa L. 25:469 of ornithine glucuronides 25:90,103 of palustroside III 25:106 of plant polyphenols 28:257,293 of tetrahydroswertianolin (THS) 25:467 of wogonin 30:291 Hepatoprotective drugs 25:100,103 Hepatoprotective effect 25:100,106, 466,472 assay method for 25:100 of Colchicum autumnale 25:472
371 of glycyrrhizin 25:466 of oleanolic acid-type glucuronide saponins 25:106 of plants 25:459 of sinomenine 25:472,476 Hepatoprotective mechanism 25:472 of coumarins 25:472 Hepatoprotective natural products 25:465 Hepatoprotective phytoconstituents 25:477 Hepatoprotective proteins 25:461 Hepatoprotective saponin 25:465 Hepatosplenomegaly 26:785 Hepatotoxcity 21:651,654 Hepatotoxic cyclic peptides 20:887-913 of cyanobacterial origin 20:887-913 Hepatotoxic principle 27:879 of Anabaena genera 27:879 of Microcystis genera 27:879 of Oscillatoria genera 27:879 Hepatotoxicity 22:8;25:461,471 cyanobacterial 9:496-499 Hepelidic acid 21:230 Hepoxilin 9:576 Hepoxilins (hydro-epoxides) 9:577 Heptaacetyl tunicaminyl uracil 1:420, 421,572 5,9-Heptacosadienoic 25:721 Heptacyclic tropone 11:125 (8 E)-Heptadeca- 1,8,dien-4,6-diyn-3,10diol 27:422 structure of 27:422 1,Z-8-Heptadecadiene 2:8 9-Heptadecenoic acid 21:189 2,3,4,5,2',3'.4'-Heptahydroxybenzophenone 25:351 Heptaketide 21:209,311 Heptamethoxyflavone 23:747;26:752 Heptanal 9:338,339 Heptanedioic acid derivative 11:117 tetraoxoalkanedioates 11:117 Heptanoic acid 26:361 Heptanolide 10:232 from Baeyer-Villiger reaction 10:232 Heptanone 30:41 oxidation of 30:41
Heptapeptide lissodinamide 25:878 Heptapeptides 25:715,883 Heptaphylline 2:118,2:119 (+)-Heptelidic acid 21:229-231 Heptenes 9:400 Heptitol 4:17;11:429 Heptobioses 4:205,206 Heptodialdopyranose derivative 4:180, 181 Wittig olefination of 4:180,181 Heptose region of oligosacchardies 4:195-216 synthesis of 4:195-216 Heptuloses 11:429 Heptulosonic 30:473 synthesis of 30:473 Heptulosonic acid analogues 30:473 Mukaiyama reaction of 30:473 15[3-Heptylachaparrinone 26:815 Heracleum L. 21:615 Heracleum sibiricum 22:522 Heracleum verticillatum 22:522 (+)-Herandulcin 16:229 synthesis of 16:229 Herbacetin-3,8-dimethyl ether 5:624 Herbacetin-8-methyl ether 3-diglucoside 5:623 Herbadysidolide 21:310 Herbal antidepressant 30:333 Hypericum perforatum as 30:333 Herbal drugs 25:44 as antitumor-promotor 25:44 Herbal formulation AV/EPP/14 28:401 against larvae 28:402 against nymphs of Boophilus microplus 28:402 Herbal medicines 24:261 activities of 24:261 HerbamideA 25:900 Herbasolide 25:692 Herbasterol 5:410 antimicrobial activity of 5:410 cytotoxic activity of 5:410 Herbicidal 24:799,867 bioassay of 24:867 biological activity 24:799 Herbicidal activity 21:435;23:73;24:819 against dicotyledonous plants 23:73
372 against monocotyledonous plants 23:73 of Piqueria trinervia 24:779, 817-819 Herbicidal antibiotic 5:592,607 Herbicides 7:398,383,384,387;25:668 Herbimycin 5:592;21:420,435;23:54 as an antitumor antibiotic 5:592 as herbicidal agent 5:592 Herbimycin A 21:442 Herbivorous crustacean zooplankton 26:355 Herbolide A-F,H,I 7:230,233 Hercynolactone 5:729,730 Herdmania curvata 21:366 Heritianin 7:185-187 Heritiera littoralis 7:176,177,180,181, 185,187,190 Heritol 7:185,187 Heritonin 7:185,187 Hernamymphine 30:582 HREIMS of 30:582 ~H-NMR spectrum of 30:582 IR spectrum of 30:582 molecular formula of 30:582 UV absorptions of 30:582 (+)-Hernandaline 30:563,594 as platelet aggregation inhibitor 30:594 Hemandezine 22:35 Hernandia 30:559-561,563-580 benzenoids from 30:562 bioactive constituents of 30:559 biological studies of 30:561 classification of 30:560 division of 30:560 economic applications of 30:559 ethnobotanical studies of 30:561 family of 30:560 flavonoids from 30:562 genus of 30:560 hemandiaceae family of 30:559 isoindole from 30:562 isoquinoline alkaloids from 30:560,562 lignans from 30:560,562 monoterpenoids from 30:562 pyridine from 30:562 species of 30:559
sterols from 30:562 subclass of 30:560 subfamily of 30:560 Hernandia albiflora 30:560 (-)-laetine from 30:564 (+)-actinodaphnine from 30:563 (+)-corytuberine from 30:563 (+)-hemagine from 30:563 (+)-hernandaline from 30:563 (+)-hernovine from 30:564 (+)-isoboldine from 30:564 (+)-isocorydine from 30:564 (+)-laurotetanine from 30:564 (+)-magnofiorine from 30:564 (+)-N-formyldehydroovigerine from 30:563 (+)-N- formylnornantenine from 30:563 (+)-N- formylovigerine from 30:563 (+)-N-hydroxyhernangerine from 30:564 (+)-N-methyl-6,7-dimethoxyisoquinolone from 30:564 (+)-N-methylactinodaphnine from 30:564 5,6-Dimethoxy-N-methylphthalimide from 30:563 6,7-dimethoxy-N-methylisoquinoline from 30:563 7- formyldehydrohemangerine from 30:563 7-formyldehydronomantenine from 30:563 7-formyldehydroovigerine from 30:563 7-hydroxy-6-methoxy- 1methylisoquinoline from 30:564 atheroline from 30:563 backebergine from 30:563 dehydrohemandaline 30:563 demethylsonodione from 30:563 hernandonine from 30:564 hemangerine from 30:564 hemanymphine from 30:564 laetanine from 30:564 laudanosine from 30:564 lindearpine from 30:564
373 monoterpene from 30:569 N-(N-methylcarbamoyl)-Omethylbulbocapnine from 30:564 N-formylnornantenine from 30:563 N-hydroxyovigerine from 30:564 N-methylcorydaldine from 30:564 sterols from 30:569 Hernandia beninensis sp. 30:560 Hernandia bivalves sp. 30:560 Hernandia catalpifolia sp. 30:560 Hernandia cordigera 5:485,561; 30:562-566,568,569 (-)-yatein from 30:569 (+)-actinodaphnine from 30:563 (+)-hernagine from 30:563 (+)-isoboldine from 30:564 (+)-isocorydine from 30:564 (+)-laurotetanine from 30:564 (+)-nandigerine (hernangerine) from 30:565 (+)-neolitsine from 30:565 (+)-N-methylactinodaphnine from 30:564 (+)-N-methyllaurotetanine from 30:565 (+)-norisocorydine from 30:565 (+)-nornantenine from 30:565 (+)-ovigerine from 30:565 (+)-reticuline (S)-reticuline from 30:566 5'-methoxypodorhizol from 18:561;30:569 5'-methoxyyatein from 30:569 anthricin from 30:568 bursehernin from 30:568 cordigerin from 30:568 hernandin from 30:569 podorhizol from 30:569 Hernandia cubensis sp. 30:560 Hernandia didymantha sp. 30:560 Hernandia drakeana sp. 30:560 Hernandia guianensis 30:562-566, 568-570 (+)-actinodaphnine from 30:563 (+)-hernovine from 30:564
(+)-laurotetanine from 30:564 (+)-nandigerine (hernangerine) from 30:565 (+)-ovigerine from 30:565 (+)-reticuline from 30:566 acetylpodophyllotoxin from 30:568 anthricin from 30:568 bursehernin from 30:568 N-methylhernovine from 30:565 N-methylnandigerine from 30:565 picropodophyllin from 30:569 podorhizol from 30:569 stigmasterol from 30:570 [3-sitosterol from 30:570 Hernandiajamaicensis sp. 30:560 Hernandia mascarenensis sp. 30:560 Hernandia moerenhoutiana 30.561,597 antimalarial activity of 30:561 antioxidant activity of 30:561 biological activities of 30:562 cytotoxic activity of 30:561 spasmolytic activity of 30:561 to retain placenta 30:561 to treat malaria 30:561 use in morning sickness 30:561 use in postpartum hemorrhage 30:561 use in treament of malaria 30:597 use in treament of morning sickness 30:597 use in treament of postpartum hemorrhage 30:597 Hernandia nukuhivensis sp. 30:560 Hernandia nymphaeifolia 26:212; 30:561,563-570,597 atheroline from 30:563 biological activities of 30:562 3-cyano-4-methoxypyridine from 30:567 dehydrohernandaline from 30:563 (-)-deoxypodophyllotoxin from 26:218;30:568 5,6-dimethoxy-N-methylphthalimide from 30:563 (+)-epiaschantin from 26:218;
374 30:568 (+)-epimagnolin from 26:218; 30:568 (+)-epiyangambin from 26:218; 30:568 7-formyldehydrohernangerine from 30:563 7- formyldehydronornantenine from 30:563 7-formyldehydroovigerine from 30:563 hernandial from 30:567 hernandonine from 30:564 hernanymphine from 30:564 (-)-hemone from 30:569 (+)-hernovine from 30:564 7-hydroxy-6-methoxy- 1-methyl lisoquinoline from 30:564 6~x-hydroxystigmast-4,22-dien-3one from 30:570 6~x-hydroxystigmast-4-en-3-one from 30:570 3~-hydroxystigmast-5,22-dien-7one from 30:569 3 [3-hydroxystigmast-5-en-7-one from 30:570 (-)-6'-hydroxyyatein from 30:569 (+)-isocorydine from 30:564 (+)-laurotetanine from 30:564 (+)-magnoflorine from 30:564 5'-methoxypodorhizol from 30:569 N-(N-methylcarbamoyl)-Omethylbulbocapnine from 30:564 (+)-nandigerine (hernangerine) from 30:565 (+)-N-hydroxyhernangerine from 30:564 N-hydroxyovigerine from 30:564 N-methylcorydaldine from 30:564 N-methylhernovine from 30:565 (+)-N-methyllaurotetanine from 30:565 (+)-N-methylovigerine from
30:565 (+)-nornantenine from 30:565 northalifoline from 30:565 nymphaeol C from 30:567 (-)-nymphone from 30:569 ovigeridimerine from 30:566 (+)-ovigerine from 30:565 ovihernangerine from 30:566 oviisocorydine from 30:567 7-oxohernagine from 30:565 oxohemandaline from 30:565 oxonantenine from 30:566 stigmasta-4,22-dien-3-one from 30:570 (+)-thalicarpine from 30:567 thalifoline from 30:566 to retain placenta 30:561 to treat malaria 30:561,597 use in postpartum hemorrhage 30:561,597 use in treament of morning sickness 30:597 (+)-vateamine-2' 13-N-oxide from 30:567 (-)-yatein from 26:218;30:569 ~-sitosterone from 30:570 Hernandia obovata sp. 30:561 Hernandia olivacea sp. 30:561 Hernandia ovigera 5:485;30:563-569 (-)-deoxypodophyllotoxin from 30:568 (-)-dimethylmataire sinol from 30:568 (-)-yatein from 30:569 (+)-epimagnolin A from 30:568 (+)-epimagnolin from 30:568 (+)-epiyangambin from 30:569 (+)-nandigerine (hemangerine) from 30:565 (+)-ovigerine from 30:565 (+)-thalicarpine from 30:567 (7R,SS,7'R,8'R)-(+)-7'-acetyl-5 'methoxypicropodophyllin from 30:567 ( 7R, 8S,7'R, 8 'R)-( +)-7 '-acetylpicropodophyllin from 30:568 1,2,3,4-dehydro de oxypodophyllotoxin from 30:568 1,2,3,4-dehydropodophyllotoxin
375
from 30:568 5'-methoxypodorhizol from 30:569 5'-methoxyyatein from 30:569 6,7-demethylenedeoxypodophyllotoxin from 30:568 6,7-dime tho xy-N-methylisoquinoline from 30:563 anthricin from 30:568 bursehernin from 30:568 caruilignan C from 30:568 dehydrothalicarpine from 30:566 deoxypicropodophyllin from 30:568 desoxypicropodophyllin from 18:600 diasesartemin from 30:568 diayangambin from 30:568 epiaschantin from 18:600 epimagnolin from 18:600 hernandin from 30:569 hernandonine from 18:600; 30:564 hemolactone from 30:569 isohernandion from 18:600 N-methylcorydaldine from 30:564 oxocrebanine from 30:565 oxothalicarpine from 30:567 ~-hydroquinone from 30:567 podophyllotoxin from 30:569 podorhizol from 30:569 Hernandia ovigera var. mascarenensis 30:562-565,568,569 (-)-yatein from 30:569 (+)-actinodaphnine from 30:563 (+)-epimagnolin from 30:568 (+)-hernagine from 30:563 (+)-hernovine from 30:564 (+)-nandigerine (hemangerine) from 30:565 bursehernin from 30:568 hemandonine from 30:564 N-methylnandigerine from 30:565 Hernandia peltata 20:522;30:562,564, 566-569 (-)-laetine from 30:564 (-)-yatein from 30:569
(+)-6-northalicarpine from 30:566 (+)-ambrimine from 30:566 (+)-efatine from 30:566 (+)-epiaschantin from 30:568 (+)-epimagnolin from 30:568 (+)-epiyangambin from 30:569 (+)-hebridamine from 30:566 (+)-malekulatine from 30:566 (+)-reticuline (S)-reticuline from 30:566 (+)-thalicarpine from 30:567 (+)-thalicarpine-2 '-N-oxide from 30:567 (+)-thalmelatine from 30:567 (+)-vanuatine from 30:567 (+)-vilaportine from 30:567 6(x,7-dehydrothalmelatine from 30:566 bursehernin from 30:568 epieudesmin from 30:568 vateamine from 30:567 Hernandia rostrata sp. 30:561 Hernandia sonora 30:562-569 (+)-corytuberine from 30:563 (+)-hernagine from 30:563 (+)-hernandaline from 30:563 (+)-malekulatine from 30:566 (+)-N-formyldehydroovigerine from 30:563 (+)-N-formylnornantenine from 30:563 (+)-N-formylovigerine from 30:563 (+)-N-methyl-6,7-dimethoxyisoquinolone from 30:564 (+)-ovigerine from 30:565 5'-methoxypodorhizol acetate from 30:569 5-methoxypodophylloton acetate from 30:569 5-methoxypodophyllotoxin from 30:569 acetylpodophyllotoxin from 30:568 anthricin from 30:568 atheroline from 30:563 backebergine from 30:563 dehydrohemandaline from
376
30:563 demethylsonodione from 30:563 hernandin from 30:569 hernandonine from 30:564 hemangerine from 30:564 isovanillin from 30:567 N-formylnornantenine from 30:563 N-methylhernangerine from 30:565 norsonodione from 30:565 picropodophyllin from 30:569 podophyllotoxin from 30:569 sonodione from 30:566 Hernandia sp. 30:561,562,588,589, 594,597 activity in antiplatelet aggregation turbidimetry assay 30:594 activity in human murine cancer cell line 30:589 activity in human tumor xenograft system 30:589 activity in mouse model 30:589 antimalarial activities of 30:588 antioxidant activity of 30:597 antiplatelet aggregation activity of 30:588 anti-tumor activity of 30:589 benzenoids from 30:562 biological activities of 30:562 cancer chemopreventive activity of 30:588 constituents of 30:562 cytotoxic activity of 30:588, 589,597 dehydrohernandaline from 30:594 (-)-deoxypodophyllotoxin from 30:595 (+)-epiaschantin from 30:595 flavonoids from 30:562 hernangerine from 30:594 (-)-hernone from 30:595 (+)-hernandaline from 30:594 in vitro 30:588 in vivo 30:589 inhibitory effects of 30:594 isoindole from 30:562
isolates from 30:594 isoquinoline alkaloids from 30:562 isovanillin from 30:594 (+)-laurotetanine from 30:594 lignans from 30:562 (+)-malekulatine from 30:594 monoterpenoids from 30:562 N-methylhernangerine from 30:594 (+)-ovigerine from 30:594 7-oxohernagine from 30:595 phytochemical studies of 30:597 pyridine from 30:562 (+)-reticuline from 30:595 role in morning sickness 30:561 role in placenta 30:561 role in postpartum hemorrhage 30:561 spasmodic activity of 30:597 sterols from 30:562 (+)-thalicarpine from 30:595 to treat malaria 30:561 (+)-vateamine-2' [3-N-oxide from 30:595 (-)-yatein from 30:595 Hernandia stenura sp. 30:561 Hernandia stokesii sp. 30:561 Hernandia tahi' nsis sp. 30:561 Hernandia tem,,'ii sp. 30:561 Hernandia voyronii 30:561,562, 564-566,569,597 (-)-laetine from 30:564 (-)-pallidine from 30:566 (-)-pallidine from 30:566 (-)-yatein from 30:569 (+)-6-northalicarpine from 30:566 (+)-ambrimine from 30:566 (+)-efatine from 30:566 (+)-epiaschantin from 30:568 (+)-epimagnolin from 30:568 (+)-epiyangambin from 30:569 (+)-hebridamine from 30:566 (+)-malekulatine from 30:566 (+)-N-methyllaurotetanine from 30:565 (+)-norisocorydine from 30:565 (+)-perillaldehyde from 30:569
377
(+)-reticuline from 30:566 (+)-thalicarpine from 30:567 (+)-thalicarpine-2'-N-oxide from 30:567 (+)-thalmelatine from 30:567 (+)-vanuatine from 30:567 (+)-vilaportine from 30:567 6ct, 7-dehydrothalmelatine from 30:566 antimalarial activity of 30:561 antioxidant activity of 30:561 biological activities of 30:562 bursehernin from 30:568 cytotoxic activity of 30:561 epieudesmin from 30:568 herveline A from 30:566 herveline B from 30:566 herveline C from 30:566 herveline D from 30:566 laetanine from 30:564 laudanosine from 30:564 lindearpine from 30:564 norpredicentrine from 30:565 ocobotrine from 30:565 spasmolytic activity of 30:561 to retain placenta 30:561 to treat malaria 30:561 use in morning sickness 30:561 use in postpartum hemorrhage 30:561 use in treament of malaria 30:597 use in treament of morning sickness 30:597 use in treament of postpartum hemorrhage 30:597 vateamine from 30:567 Hernandiaceae 18:558 Hernandin 18:579-594 synthesis of 18:579-594 Hernandion 18:552,555 from Hernandia ovigera 18:552 Hernandonine 30:564,589 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:589 (+)-Hernandulcin 15:14-16
6S, l'S-Hernandulcin 15:14 (+)-Hernaudulcin 27:13,21 structure of 27:21 Herniaria fontanesii 26:52,54 litholytic properties of 26:52,54 Herniaria glabra 26:50,51 Herniaria hirsuta 26:50 in arrthritis 26:50 in infections of urinary tract 26:50 in infections of respiratory tract 26:50 in kidney disorders 26:50 in neural catarrh 26:50 in neuritis 26:50 in purifying blood 26:50 in rheumatism 26:50 Herniaria saponins A-D 26:50-52 Herniarin 7:204,205,224;18:974,976; 23:354 Hernolactone 18:554,565,569,566 from Hernandia ovigera 18:569 (-)-Hernone 26:212,199;30:569,587, 590,595 activity in human cancer cell lines 30:589 as platelet aggregation inhibitor 30:594 cytotoxicity of 26:212 cytotoxic effect of 30:589 (+)-Hernovine 30:564,589 cytotoxic effect of 30:589 Heroin 18:48 Herpes infection 30:400,401 role of vericella-zoster virus in 30:400 Herpes simplex virus 26:223 ;30:394, 395,400,412 cause of 30:394 inhibitor of 30:395 type 1 (HSV-1) 30:394,400 virus type II (HSV-2) 30:394, 400 Herpes simplex virus type 1 (HSV-1) 30:743,752 antiviral activity 30:743 Herpes simplex virus type II 30:752
378 Herpestis monniera 22:513 for epilepsy and noctumal epilepsy 22:513 Herpesviridae family 30:401 infections caused by 30:401 Herpetomonas curzi 2:298 Herpetomonas mmuscarum 2:298,301 Herpetomonas samuelpessoai 2:298; 26:138 polysaccharides in 2:299-301 Hertellin A 23:403 Hertellin C 23:403 Herveline A 30:566,583,597 13C NMR of 30:584 ~H homonuclear correlation spectroscopy (COSY) of 30:584 1H NMR of 30:583,584 EIMS of 30:584 heteronuclear multiple-bond coherence (HMBC) spectrum of 30:584 heteronuclear multiple-bond quantum coherence (HMQC) spectrum of 30:584 in murine model 30:597 in vivo 30:597 molecular formula of 30:583 UV absorptions of 30:583 Hervelines A-D 30:595,596 antimalarial activity of 30:595 antiplasmodial activity of 30:596 Hesperethusa crenulata 22:522 for epilepsy 22:522 Hesperetin 25:469,541,618;26:757,762 Hesperidin 22:325,423,429,436;23:747; 26:744,745,752,759,766,768 Hesperidin (3',5,7-trihydroxy-4'methoxyflavanone-7-rutinoside) 29:579 effects on ACE 29:579 Hesperidinase 7:270;25:210 Hesperiphona vespertina 5:836;8:151, 152;9:152 hemoglobin components of 5:836 of ot-cedrene 5:790 of artemisinin 5:25,26 of angelic acid 5:778
oftiglic acid 5:778 of 7-hydroxyfrullanolide 9:152 spectra of 8:151,152 HETCOR 21:764;26:11,13,34,37 ofbisdesmoside 26:41 ofdianchinenoside E&F 26:34 of SAPO 26:30,41,50 Heteonuclear correlation 21:764 Heterakis spumosa 26:482 Hetero Diels-Alder reaction 16:654 addition of 16:654 approaches to 16:456 asymmetric 11:260-267 diastereoselective 12:424,425 enantioselective 11:260-267 for nepetalactone synthesis 4:604,605 for tylophorine synthesis 4:604,605 gephyrotoxin 223AB by 4:606 gephyrotoxin by 4:606 iminodienophile in 4:604,605 intramolecular 6:449;14:757, 758;19:43,223 intramolecular Lewis acid catalysed 1:553 lysergic acid by 4:604,605 monomorine I by 4:606 of 2-methoxybutadiene 12:257 oxazoles in 4:604 pyran adduct from 12:257 reaction of 16:439 tetrazines in 4:604 triazines in 4:604 using nitroso dienophiles 1:378 with ethyl glyoxalate 12:257; 13:69,177,187,490,625,757,758 [3-amino acid by 12:158 Hetero Diels-Alder type cycloaddition 24:235 1 [3-Heteroatom-substituted carbapenems 12:165 synthesis of 12:165 Heterobasidion annosum 21:212 Heterocentron roseum 23:404,405 Heteroclitin F&G 26:259 Hetero-Cope rearrangement 8:205 Heterocyclic bicyclic substrate 17:497
379 Heterocyclic compound 17:614-622 semi-synthesis of 17:614-622 N-Heterocyclic compounds 12:445 Heterocycloaddition 1:359-392 Heterodera 26:429,432 Heterodera cajani 26:469 Heterodera glycines 26:429,454,456, 466,467,473,477 Heterodera rostochiensis 26:437 Heterodera schuchiti 26:481 retro-Hetero-Diels Alder reaction 26:113 Heterodienophiles 4:143 in D-allo-threonimal 4:143 in Diels-Alder reaction 4:563 Heterolytic dissociation 6:307,308 Heterolytic fragmentation 13:575 Heteromercuration 1:382 ofcarbamates 1:382 Heteromorpha trifoliata 7:415;21:600; 22:97; 23:341 Heteronema 6:23 halopuupehenones from 6:23 puupehenones from 6:23 Heteronuclear correlated spectroscopy (HETCOR) 5:4,749;30:587 of (-)-hernone 30:587 Heteronuclear correlation (HETCOR) 23:27 Heteronuclear Multiple Bond (HMBC) Connectivity spectra 9:147-153 of griffithine 9:149,150 Heteronuclear multiple bond correlation (HMBC) 23:27 Heteronuclear multiple-bond coherence (HMBC) 30:584 ofherveline A 30:583 Heteronuclear multiple-bond quantum coherence (HMQC) 30:584 ofherveline A 5:314;21:764; 30:583 Heteronuclear shift correlated spectra 9:127,151-154,156-157 Heteropappus altaicus 21:634,660 Heteropappus biennis 21:660 Heterophyllae 7:205 coumarine-hemiterpene ethers in 7:205 Heterophylliin A 23:403
Heterophylliin B 23:403,410 Heterophylliin G 23:403 Heterophyllin 28:230 biological activity of 28:230 Heteropolysaccharides 5:289,290,292, 294 Heteropora alaskensis 17:90,92 Heteropsylla cubana 21:595 Heteropyxis natalensis 21:599 Heterorhahditis nematodes 26:471 Heterostilbene photocyclization 3:355 Heterotropa takaoi 17:348 Heterotrophic cell lines 7:205 Heteroxanthin 6:150 Heteroxenia fuscescens 21:282 Heteroyohimbine alkaloids 25:30 Hexaacetate 6:400 of 2,2-dideoxy-2,2'-diphtalimido,13-trehalose 6:400 Hexabranchus sanguineus 17:16,19:609 Hexacarbonyldicobalt 12:175 5,9-Hexacosadienoic 25:721 (5Z,9Z)-5,9-Hexacosadienoic 26:82 total synthesis of 26:82 5,5 '-Hexadecamethylene- 1,1 ',3-trihydroxy-4,3'-diphenylether 30:136 structure of 30:136 12-O-Hexadecanoyl- 16-hydroxyphorbol-13-acetate (HHPA) 25:45 induced edema inhibition (HPA) 25:46 (Z)-9-Hexadecenoic acid 26:70 methanolysis of 26:65 Hexadecyltrimethylammonium hydroxide (CTAH) 18:832 6-Hexadecyn- 1-ol 2:15 CI(NO) spectrum 2:15 3,4,5,6,18,19-Hexadehydroochropposinine 1:124 Hexadeuterated abscisic acid 27:353 Hexadeutrarated reserpine 25:9 (2E,4E)-2,4-Hexadienoic acid (sorbic acid) 10:149 Hexaenal 6:264-267 acylation of 6:264-267 from N-acetyl amphotericin B methyl 6:264-267 Hexaenoic acid 9:568
380 Hexaflouroacetylacetonate derivative 16:384 Hexafluoro-25-hydroxy-vitamin D2 derivatives 9:518 Hexaglycosides 7:272,278,281,288-290 Hexahydrobenzofuran component 12:24 of avermectins 12:24 parsons approach for 12:24 (-)-Hexahydrocannabinol 19:215 9-nor-9-OH-Hexahydrocannobinol (HHC) 30:195,196 analgesic activity of 30:195 structure of 30:197 Hexahydrocurcumin 17:363,368 (S)-Hexahydrocurcumin 17:365 Hexahydrodibenz [d,g] azecines 6:492, 493 [1] benzothieno analogues of 6:492 from dibenzothieno analogues of 6:492 synthesis of 6:492,493 (S)-Hexahydromandelic acid 6:291,292 Hexahydronaphthalene portion of compactin 11:340-343 Hexahydronaphthalene portion of mevinolin 11:343-345 Hexahydroporphinoids 9:603 Hexahydroporphyrins 9:605 Hexahydroproaporphines 2:255 Hexahydropyrrolocarbazole 1:72 synthesis of 1:72 (+)-a-Hexahydrostepharine 2:256 (+)-[3-Hexahydrostepharine 2:256 Hexahydroxydiphenic acid 15:33 4,4',5,5',6,6'-Hexahydroxydiphenic acid dilactone 27:755 3,5,7,8,3',4'-Hexahydroxyflavone 8-0glucoside) 29:572 313,1613,2113,22cx,23,28-Hexahydroxyolean- 12-ene 18:649 Hexaketide 21:208 Hexalin alcohol 13:601 asymmetric synthesis 13:601 Hexalone 15:241 Hexamer 8:369,370 cyclization reaction of 8:369,370
Hexamethyl phosphoric triamide 11:353 Hexamethyl phosphoric triamide (HMPA) 13:63 Hexamethylphosphoric acid (HMPA) 8:316,318-321,324,326,330,331, 333-336,341-343,346 Hexanortriterpenoid 9:102,297,298 Hexanoyl CoA 11:194 19'-Hexanoylfucoxanthin 6:134,135 CD correlation of 6:137 distribution of 6:134,135 ozonolytic degradation of 6:137 19'-Hexanoyloxyfucoxanthin 6:142,143 19'-Hexanoyloxyisomytiloxanthin 6:142,143,151 19'-Hexanoylparacentrone 6:136 Hexapeptide 10:289;25:887 cyclization of 10:289 Hexapeptide biotratamide 25:878 Hexaphenylhydrazone 9:580,581 Hexaploid 22:608 Hexaprenyl-hydroquinone sulfate 28:676 as H+/K+-ATPase inhibitor 28:676 Hexapyranose nucleosides 4:6 in synthesis of 4:6 deoxynucleosides 4:237 Hexasaccharides 7:31 trans-Hexenal 6:282,284 synthesis of 6:282,284 Hexepi-uvaricin 18:207-211 synthesis of 18:207-211 Hexitols 7:181 Hexodialdopyranoside derivative 4:171 Wittig olefination of 4:171 Hexokinase 7:387 Hexopyranose derivatives 10:426-428 Hexopyranose nucleosides 4:222-225 synthesis of 4:222-225 Hexopyranose-purines 4:224 Hexopyranosyl-pyrimidines 4:224 Hexosamines 22:441 fl-Hexosaminidase 25:939 3-Hexyl-4,5-dithiacycloheptanone 25:842 3-Hexyl-5-methylindolizidine 27:241 diastereomers of 27:241
381 (5Z,9Z)-3-Hexyl-5-methylindolizidine 6:450,451 synthesis of 6:450,451 (+)-Hexylitaconic acid 21:240 Heynea trijuga 2:267 (-)-Heyneanine 5:127 (-)- 19S-Heyneanine 5:127 (+)-Heyneanine 5:127 Heyneanine 9:171 Heyneanol A 26:568 Hezahydrozydiphenic acid 746 Hg(H) mediated Ritter reaction 11:281, 282 m-HHA 25:925 HHPA 25:55 inhibitory effects on 25:55 HHPA induced edema (HPA) 25:45 HHPA-induced inflammation 25:56 Hibiscones A-D 7:185,186 Hibiscoquinones A-D 7:185,186 Hibiscus abelmoschus L. 22:522 for hysteria 22:522 Hibiscus rosa-chinensis 7:180,183,195; 28:400 Hibiscus tiliaceus 7:185 Hibiscus vitifolis 29:572 Hiburipyranone 15:386 9,11-Hidechtoro- 13-demotheylisodysidenin 25:889 (+)-313-Hidroxinagilactone F 28:503 synthesis of 28:503 Higenamine 21:57 High dilution technique 11:153,154 High fat-diet-treated group 27:401 High performance liquid chromatography (HPLC) 2:368,375,393, 397,404;5:621,622,624,648-650; 9:460-464 High pressure technique 4:121 [4+2] cycloaddition by 4:121 in Diels-Alder reaction 4:112 High resolution mass spectrometry 21:584 High sugar diet-treated group 27:410 High TEQ 30:764 High-accumulating lines 7:98-103 Higher plants 7:121-123 gene transfer in 7:121-123
High-fat diet-induced model 30:80 of obesity 30:80 High-fat diet-induced obesity 30:82 prevention of 30:80,82 High-performances liquid chromatography 21:537 High-resolution electron impact mass spectrometry (HREIMS) 30:570 of demethylsonodione 30:570 High-temperature short-time (HTST) treatment 23:786 Hikizimycin 1:398,410-417 ;4:241,245; 11:430,449;26:493 Hikosamine 11:449 Hilbert-Johnson reaction 1:399,400; 4:223,224,230,239 Himandravine 21:56 Himax 28:416 acaricidal action of 28:416 against demodectic mites 28:416 against psoroptic mites 28:416 against sarcoptic mites 28:416 Himbacine 21:56;22:19 Himerometra robustipinna 7:266 Himeyoshin 7:233 Himi-ketal formation 2:237,238 Hinckdentine A 17:88 Hincksinoflustra denticulata 17:85,88 (+)-Hinesol 16:239 Hinge-peptide 18:930-958 Hinokinin 18:566;26:216,231 (-)-Hinokinin 26:192,215,216 Hinokiol 2:403;29:101 activity in CRG bioassay system 29:101 Hinokitiol 21:621 Hippamine 26:610,614 Hippeastrine 22:522,539 Hippeastrine 26:614 Hippeastrum sp. 26:614 Hippeastrum vittatum 22:522 Hippocampal neurons 22:26;30:376 in infantile autism 30:376 morphology of 30:376 Hippocampus 22:508,509 Hippocasculin 7:143 from Aesculus hippocastanum 7:143 Hippocratea 18:741,754;23:651,652
382
Hippocratea indica 5:749 Hippocratea volubilis 30:661,646 lupane caffeoyl esters from 30:646 volubilide from 30:661 Hippocrateine I 23:680 Hippocrateine II 23:680 Hippocrepis balearica 19:117
Hippocrepis comosa 117 Hippodiplosia insculpta 17:90,92 Hippospongia A-F 25:688
Hippospongia metachromia 5:430 Hippospongia sp. 5:432;25:698,721, 871;28:690 Hippospongin 3:157,158 Hippuric acid 9:387;25:928,929 Hiptagamadablota 19:117 Hiptage benghalensis 22:522 for epileptic fits 22:522 Hiptagin 27:522 Hirama synthesis 12:15,16 biomimetic 12:16 of avermectin oxahydrindene subunit 12:15,16 Hiravanone 23:552 Hircinol acid 23:342 HIRE 24:951-954 antibiotic activity of 24:953-954 bioactive compounds from 24:951-954 bioactivity of 24:951-954 Hirsutanonol 25:543 Hirsutene 3:7,12;22:195,201 synthesis of 3:7,12,13,17,18, 20,22,40,65;4:588;13:34-37 (+)-Hirsutene 4:588 Hirsutenone 25:543 Hirsutic acid 3:5,7,12,65 (+)-Hirsutine 13:67 Hirsutine 21:52,79;25:31,32 chromotropic and oxidole alkaloids 25:32 His215 family inhibitors 26:368 Hispaglabridin A 28:228 biological activity of 28:228 Hispidulin 7:227;19:773;30:750 structure of 30:750 Hispidulin-7,4'-disulphate 5:655 Hispidulin-7-sulphate 5:655
Histamine 15:328;21:10,14,19,50,660; 22:111,136,437;25:516,520,532,536, 538,612,613,701,719;30:192 as pain mediator 30:192 from vessels 30:192 Histamine induced edema 25:46 Histamine production 25:611 Histamine receptor 25:611,34 Histamine release 25:47 inhibition of 25:47 Histamine release inhibition 23:357; 24:914-917 by coumarine 23:357 by oosponal 24:914-917 of Morus spp. 24:914-917 Histamine release inhibitor 28:257,293 polyphenols as 28:257,293 Histamine secretion 25:936 Histamine/peptide leukotriene C4 (LCT4) 25:275 Histamine-induced hind paw edema 26:401 Histanecine 19:149 isolation of 19:149 necine base 19:149 Histidine 22:20;25:334,335,526,813; 27:78 Histidine decarboxylase 25:612 Histidine kinases 25:526;27:824 Histidine-rich protein (HRP) 25:334, 342,360 Histidine-rich proteins II and III 25:334 Histiopteris incisa 26:122 Histological examination 27:310 of consuming stevioside effects 27:310 of reproduction tissue 27:310 Histone HI 25:526 Histone phosphorylation 7:387 Histones 30:79 Histoplasma capsulatum 5:307;22:57, 248;23:382 Histoplasma duboisii 5:307 Histoplasma farcinosum 5:307 Histoplasma sp. 5:325,328 Histoplasmosis 2:422 (-)-Histrionicotoxin 16:427,432,453, 19,14,15-16
383 Histrionicotoxins 11:244;18:698,19:3, 14-17;21:70,73 Hitachi high throughput purification (HTP) 29:651 advantages of 29:656 COX-1 inhibition profile by 29:657 for mushroom tyrosinase inhibition 29:656 high-pressure type by 29:654 hit rate in 29:656 HTP/MS spectrum with 29:655 HTP/UV chromatograms with 29:654 via chromatography system 29:654 Hitachimycin 10:153;23:51 HIV (human immuno deficiency virus) 7:12 HIV- assay 19:757 HIV enzymes 30:397 HIV reverse transcriptase 30:397 HIV integrase 30:397 HIV infection treatment 30:396 role of carbohydrates in 30:396 role of sulphated polysaccharide (PS) in 30:396 HIV infections 30:396 chemotherapy of 30:396 HIV inhibition 23:704;30:399 by salaspermic acid 23:704 in vitro 30:399 HIV inhibitory activity 28:121 of equisetin 28:121 HIV inhibitory effects 23:706 ofbetulinic acid 23:706 HIV integrase (IN) 25:941,942;30:226 against AIDS 30:226 mechanism of action 30:226 HIV protease 30:397 role in integration 30:397 HIV replication cycle 30:226 role ifintegrase in 30:226 role ofprotease in 30:226 role of reverse transcriptase in 30:226 HIV therapy 30:397 dextran sulphate in 30:397 pentosan sulphate in 30:397
chondroitin sulphate in 30:397 heparin in 30:397 HIV whole cell assay 19:757 HIV-1 22:675;30:397 inhibitor of 30:397 in vitro 30:397 HIV-1 IN inhibitor 30:228 trifluoromethyl pharmacophore as 30:228 HIV-1 infected H9 cells 30:226 lithospermic acids effect on 30:226 HIV-1 infection 30:399 inhibitory effects on 30:399 HIV-1 integrase 30:226 effect of natural polyphenols on 30:226 HIV-1 integrase inhibition 30:226 in vitro 30:226 HIV-1 integrase inhibitors 30:218,227 lithospermic acid A type of 30:227 lithospermic acid B type of 30:227 HIV-1 p24 antigen 30:396 inhibitor of 30:396 HIV-1 protease 29:574 absinthin (guaine sesquiterpene dimer) effects on 29:574 absintholide (guaine sesquiterpene dimer) effects on 29:574 HIV-1 protease inhibitor 24:489 indinavir as 24:489 HIV-1 reverse transcriptase (RT) 28:702 clathsterol against 28:702 HIV-1 RT inhibition 26:224 by anolignan A&B 26:224 HIV-protease 25:941,942 HIV-protease inhibitor 24:489 ritonavir as 24:489 saquinavir as 24:489 HIV-reverse transcriptase inhibitor 30:412,400 Hiyama reagent 12:36 Hiyama-Ozaki reaction 3:99 HK-mediated neurotoxicity 26:992 HL-60 cells 22:616,617 HL-60 leukemia cell 21:637
384
HLADH 17:479,481 HLADH-catalyzed reactions 17:483 HMB (hydroxymethylbilane) 9:591, 592,595 HMBC 21:764,767 HMBC and NOE correlations 28:26 of 5,7,2 ',4'-tetrahydroxy-3geranylflavone 28:26 HMBC correlations 26:9,13,15,21,25, 29,34 ofbisdesmoside 26:41 of dianchinenoside E 26:34 of SAPO 26:30,41,50 of saponarioside C 26:15,25 of saponaside A 26:21 ofvaccaroside D 26:29 HMG-CoA reductase 5:407;7:108,109, 111,112;15:450 HMGR 24:373-376 role of cholesterol oxides 24:351-398 HMPA 19:415-416 HMPT 26:1091,1092 antimicrobial activity of 26:1091,1092 HMQC 21:764,767 HMQC/HSQC experiment 26:11,34,37 ofbisdesmoside 26:41 ofdianchinenoside E&F 26:34 of SAPO 26:30,41,50 HMR1826 21:176,177 preclinical development of 21:176 HMTP 26:1099 antimicrobial activity of 26:1099 Ho oils 25:140 HOABA 27:346 formation of 27:346 exo-Hobartin- 15-ol 11:299,300 Hobartin- 19-ol 11:305 aristolasicol from 11:305 aristolasicolone from 11:305 aristolasicone from 11:305 aristotelinine from 11:305 oxidation of 11:309 serratenone from 11:305 sorelline from 11:305 synthesis of 11:309
(-)-Hobartine 11:290 absolute configuration of 11:290 (+)-aristoteline from 11:292-295 biomimetic synthesis of 11:287-291 from Aristotelia serrata 11:278 from (-)-[3-pinene 11:281,282 synthesis of 11:280-283 Hobartine 9:178 Hobartine derivative 11:298,299 19-substituted 11:309,310 synthesis of 11:309,310 Hobartine-aristoteline 11:292-295 transformation of 11:292-295 Hodgkin's disease 4:29;22:343 vinblastine for 14:805 vincristine for 14:805 Hodgkinsin 30:205 antinociceptive activity of 30:205 in pin model 30:205 in thermal model 30:205 Hoffmann degradation 18:51 Hoffmann rearrangement 1:410,411; 3:313;19:14 Hoffmann's cycloaddition 18:257 Hoffmann-LaRoche 28:71 vitamin A synthesis by 28:71 Hoffmann-Loeffler photocyclization 6:437 of N-chloroamines 6:437 Hofmann degradation 6:480,489;9:547, 548;14:771-773,793-795 Hofmann elimination 6:481,488;16:53 Hofmann reaction 14:868 HOHAHA spectrum 26:10,21,29,34 ofbisdesmoside 26:41 ofdianchinenoside E 26:34 of saponariosides A&C 26:10,21 ofvaccaroside D 26:29 Holacanthone 7:396;5:38-41 Holarrhena floribunda 22:523 Holarrhena sp. 26:837 Hollocellulose 7:195 Holometamolous 22:398 Holostane 17:118 Holostanol 7:267,268;28:588 structure of 28:588
385
Holothuria atra 7:269 holothurin A from 7:269 holothurin B from 7:269 holothurin Bl from 7:269 Holothuria edulis 7:269 holothurin A2 from 7:269 Holothuria floridana 7:269 holothurin A~ from 7:269 holothurin A2 from 7:269 holothurin B~ from 7:269 Holothuria floridea 21:315 Holothuria forskali 28:592 Holothuria grisea 7:269 holothurin AI from 7:269 Holothuria leucospilota 7:268;15:87 holothurin A from 7:268 holothurin B from 7:268 holothurin from 7:268 Holothuria lubrica 7:269 holothurin A from 7:269 holothurin B from 7:269 Holothuria mexicana 7:281 ;26:72 Holothuria pervicax 15:92;28:720 ganglioside HPG-8 from 28:720 Holothuria scabra 7:270 Holothuria squamiera 7:269 holothurin A from 7:269 holothurin B from 7:269 Holothuria tubulosa 15:104;17:134 Holothuria vagabunda 7:267,268 Holothuriidae 7:268,280 Holothurin 7:267-282,303;15:87 Holothurin A 21:315;28:592 Holothuria leucospilota 28:592 Holothurin A 7:268 from Holothuria atra 7:268 from Holothuria graeffei 7:269 from Holothuria leucospilota 7:268 from Holothuria lubrica 7:269 from Holothuria squamifera 7:269 LDs0 of 7:280 Holothurin A~ 7:269 from Holothuriafloridane 7:269 from Holothuria grisea 7:269 Holothurin A2 7:269 from Bohadschia graeffei 7:269
from Holothuria edulis 7:269 from Holothuriafloridana 7:269 Holothurin B 7:269 from Holothuria atra 7:269 from Holothuria graeffei 7:269 from Holothuria leucospilota 7:268 from Holothuria lubrica 7:269 from Holothuria squamifera 7:269 Holothurin B! 7:269 from Holothuria atra 7:269 from Holothuriafloridana 7:269 Holothurinogenin 7:267,268 Holothuroidea 7:265,267-282;15:43, 87-94;21:314 Holotoxigenol 7:277,278 Holotoxin A 7:277-279 from Stichopusjaponicus 7:277 Holotoxin A2 7:277-279 Holotoxin B 7:277-279 from Stichopus japonicus 7:277-279 Holotoxin B1 7:277-279 Holotoxin C 7:280 Holotoxins A, AI, B and Bl 15:87 from Parastichopus californicus 15:87 from Stichopusjaponicus 15:87 Holstiine 26:1048 Holton's taxol synthesis 12:220 Homanindole A 25:863 Homarus americanus 19:668 Homatropine 22:732,738 Homidium 26:786 Homoaldol reaction 8:156,157 Homoallylic alcohol 11:346,347 from epoxide 11:346,347 with vinylmagnesium bromide 11:346,347 Homoallylic coupling 10:118 Homoarginine 9:499 Homobautrachotoxin 22:35 25-Homobrassinolide 16:352;19:253, 225 synthesis of 19:258 (+)-Homobuxaquamarine 2:179,2:180, 205 (-)-Homocamphor 16:149
386
(+)-cis-Homocaronic acid 16:221 Homocarotenoids 7:317,318,355-364 25-Homocastasterone 16:337 from acetonide 16:337 ]3-Homochelidone 25:539 (+)-Homochelidonine 14:769,796 from berberine 14:796 synthesis of 14:796 Homochiral (+) synthesis 29:498 by Boyer and Lallemand 29:499 by French research groups 29:498 Homochiral auxiliary 1:578 C2-Homochiral cyclopropenes 14:507, 508 Homochiral diol auxiliaries 1:579-582 Homochiral ketone auxiliaries 1:579, 583,584 Homoconjugated oxo compounds 2:170 Cotton effect of 2:170 helicity in 2:170 Homocoriolic acid 13:315 Homocylindrocarpidine 5:127 Homoditerpene 17:22 Homodolastain 25:3;25:902 28-Homodolicholide 16:335 28-Homodolichosterone 16:335 Homoenolate ions 3:217 from allylic esters 3:217 Homoeriodictyol 7:228;30:746 structure of 30:746 Homoerythrinan alkaloids 3:480-486 synthesis of 3:480-486 Homogeranoitrile bromohydrin 6:64 spirolaureone from 6:64 Homohalichondrins A 5:378,380,382 Homohalichondrins B 5:378,380,382 Homohalichondrins C 5:378,382 Homoharringtonine 21:97;22:29 Homoisoflavan 5:17,18,20,23,24 Homoisopavine base system 6:471 synthesis of 6:471 Homologation 6:32;11:257,258, 462-464;12:82;14:175 Homologous sequences 30:831 of chymotrypsin 30:831 of earthworm chymotrypsinogen 30:831 of F-III- 1(2) 30:831
of human leukocyte elastase (HLE) 30:831 of lugworm chymotrypsinogen 30:831 of pocine pancreatic elastase (PPE) 30:831 of trypsin 30:831 ofU(t)-PA, plasmin 30:831 Homolycorine 20:325,347,353,468; 26:618 25-Homolyphasterol 16:352 Homolytic dissociation 6:307,308 c~-Homonojirimycin 10:544,545 from Omphalea diandra 10:544 Homonojirimycin 11:267 (+)-~-Homonojirimycin 11:431,432 synthesis of 11:431,432 (+)-Homononactate 18:253 Homonuclear 2D J-resolved spectra 9:139,140 Homonuclear correlation spectroscopy (IH-IH COSY) 5:3 Homonuclear Hartmann-Hahn spectroscopy (HOHAHA) 9:146,149, 151-153,158,159 of griffithine 9:149 Homooligomers 27:768 of trans-resveratrol 27:768 Homophthalate 11:119 Claisen condensation of 11:119 with acetoacetate dinion 11:119 Homophthalic acid amide 11:117 (R)/(S)-Homoproline 13:507,508 synthesis of 13:507,508 Homoptera 22:398 Homopterocarpin 20:730,20:774 Homopumiliotoxins 19:52 Homoricinoleic acid 13:315 31-Homorifamcin W 23:61 Homosapiens 21:101 Homostatine derivatives 12:477 Homoteasterone 18:507 from Raphanus sativus 18:507 Homothallin II 21:223 Homothienamycin 8:262 synthesis of 8:262 Homotriterpenes 9:267 Homovanillic acid 22:671
387
Homphymia conferta 25:793 Honey 28:385 formic acid in 28:385 Hongshengma 27:395 Honokiol 26:217,227,240,249,254 inhibitory activity of 26:217 as PAF-induced inhibitor 26:240 Honokiol (lignan) 29:582 effects on MMP 29:582 Honyumine 13:348,349 Hop-17-ene 25:59,65 Hopane triterpenes 22:107 Hopanes 22:95,107 Hopea brevipetiolaris 23:547 Hopea malibato 23:547 Hopeaphenol 23:533;26:561 (-)-Hopeaphenol 26:561 (+)-Hopeaphenol 26:561 Hoppe coupling 10:15 Hordatines 27:765 Hordenine 25:531 Hordeum 29:593 Hordeum lipid transfer proteins 29:593 effects on barley malt cysteine endoproteinases 29:593 Hordeum vulgare 21:91,504;27:191, 765;29:593 Horeau's method 5:146,149;9:25,26,28, 402;12:313;15:76,270,475;20:27; 21:751 Horeau's partial resolution method 5:371 Horhammerinine 2:375 Horminone 20:673 from Salvia acetobulosa 20:673 from Salvia candidissima 20:660 from Salvia multicaulis 20:673 from Salvia napifolia 20:670 from Salvia tomentosa 20:667 from Rabdosia lophanthoides var. gerardiana 15:173 Horminone-18-oic acid 20:661 from Salvia divaricata 20:661 Hormodendrum sp. 5:325 Hormone-activated guanylate cyclase (GC) 25:519 Hormone-activated receptor tyrosine kinase 25:518
Hormone-like substances 6:538 Hormones 18:819-866;19:627-687; 22:25 bioactive conformations of 18:819-866 Hormosira banksii 26:440 Hormosirene 21:305 Homer Bestmann oxidation 8:207 Homer reaction 6:285,286 Horner-Emmons carbon elongations 29:127 in sesquiterpenoids drimane-type synthesis 29:127 Horner-Emmons condensation 1:410, 411;10:13-17,19;11:432;14:129; 16:655;18:288 Horner-Emmons coupling 14:115,123 Horner-Emmons olefination 10:534, 441,442;14:126;16:460;18:288, 633 Horner-Emmons olefination procedure 30:458 for ketene dithioacetals 30:458 Horner-Emmons reaction 1:448,450; 5:828;8:16,209,270,271 ;9:356;10:43; 13:175,210,570;14:593 ;18:481,586; 19:14,45,62;20:567,575,580,585, 588,591,595,596,599,606;30:32 Horner-Wadsworth-Emmons condensation 19:529 Horner-Wadsworth-Emmons olefination 20:567;21:432 Horner-Wadsworth-Emmons reaction 12:30;20:72-74;30:34,46 Horner-Wittig olefination 6:545;9:525; 546;10:157,159,164;16:673 ;19:448; 20:702 Horner-Wittig-type reagent 19:452 Horseradish peroxidase (HRP) 5:497, 498;6:519;14:820,821 ;15:366; 26:1133;30:844 Horsfieldia iryaghedhi 5:753 Horsfieldin 5:753,754 Hortensin 5:14,15 Hortia arborea 4:400 furanocoumarin from 4:398 Hortia regia 22:400
388
Hortiolone 4:396,398 from furanocoumarin 4:396,398 synthesis of 4:396,398 Hoslundal 2:129,2:135 Hoslundia opposita 2:129;22:523 for epilepsy 22:523 for convulsions 22:523 Hoslundin 2:129,133,135 Hoslundiol 2:129,134,135 Host microorganism selectivity 23:42 Hosta longipes 21:643 Hosta plantaginea 21:637 Host-guest complexes 13:328 Host-mediated activity 25:431 of Chlorella vulgaris strain CK 22 (CVs) 25:431 Host-mediated antitumor activity 23:445 of tannic acid 23:445 Host-mediated immuno-modulator 30:768 CVE as 30:768 Host-splenomegaly response 30:4 inhibition by (+)-discodermolide 30:4 Hot CNSL bat process 9:330,331 Hot plate test 30:207,802,804,581 activity of (-)-menthol in 30:207 for determination of antinociception 30:802 ofpeptide 30:804 Houk's "inside crowded" model 12:57 Houk's "outside crowded" model 12:58 Houk's concept 11:240 House dust 24:914-917 contraction with tachyphylaxis 24:914-917 House dust mites 28:417 Actinodaphne lancifolia against 28:419 benzyl benzoate against 28:418 Cinnamomum camphora against 28:419 Cinnamomum japonicum against 28:419
Dermatophagoides farinae against 28:417
Dermatophagoides pteronyssinus against 28:417
Euroglyphus maynei against 28:417
Lindera umbellata against 28:419
Melaleuca acacoides against 28:419
Melaleuca symphycarpa against 28:419
Neolitsea sericea against 28:419 Persia thunbergii against 28:419 Taiwania cryptomerioides against 28:418 tannic acid against 28:418 treatment of 28:418 House procedure 10:308,309 House's conditions 12:46,47 Hovenia dulcis Thumb. 15:36;21:659, 674 ;24:273 ;27:40 gymaemasaponin III from 27:41, 43 gymaemasaponin IV from 27:41, 43 gymaemasaponin V from 27:41, 43 gymnemic acid I from 27:41,42 gymnemic acid II from 27:41,42 gymnemic acid III from 27:41, 42 gymnemic acid IV from 27:41, 42 gymnemic acid V from 27:41,42 gynmemic acid VI from 27:41, 42 gynmemic acid VIII from 27:41, 42 gymnemic acid IX from 27:41, 42 gymnemic acid X from 27:41,42 gymnemic acid XI from 27:41, 42 gymnemic acid XII from 27:41, 42 gymnemic acid XIII from 27:42, 42 gymnemic acid XIV from 27:41, 42 gymnemic acid XV from 27:41, 42,45 gynmemic acid XVI from 27:41,
389 42,45 gymnemic acid XVII from 27:41,42,45 gymnemic acid XVIII from 27:41,42,45 hoduloside I from 27:41 hoduloside II from 27:41 hoduloside III from 27:41 hoduloside IV from 27:41 hoduloside IX from 27:41 hoduloside V from 27:41 hoduloside VII from 27:41 hoduloside VIII from 27:41 hoduloside X from 27:41 hovenoside I from 27:41 jujubasaponm II from 27:41 jujubasaponln III from 27:41 jujubasaponm IV from 27:41 jujubasaponm V from 27:41 jujubasaponan VI from 27:41 jujubasaponin Zizyphus saponin III from 27:41 jujuboside B from 27:41 jujuboside B from 27:41 saponin C2 from 27:41 saponin E from 27:41 saponin H from 27:41 16,17-seco-dammarane triterpene glycoside from 21:659 sitakisoside XIII from 27:41 sitakisoside XVI from 27:41 sitakisoside XVIII from 27:41 sltakisoside I from 27:41 sitakisoside II from 27:41 sitakisoside III from 27:41 sitakisoside IV from 27:41 sitakisoside IX from 27:41 sitakisoside V from 27:41 sitakisoside VI from 27:41 sitakisoside VII from 27:41 sitakisoside VIII from 27:41 sitakisoside X from 27:41 sitakisoside XI from 27:41 sitakisoside XII from 27:41 zlziphin from 27:41 Zizyphus saponin I from 27:41 Zizyphus saponin II from 27:41 Hoveniodulciosides A1,A2,B 1 and B2 21:658
Hovenolactone 27:45,47 structure of 27:47 Hovenosdie I 27:41,45,46 structure of 27:46 Hoxax inella sp. 25:762 Hoya austrulis R. 22:523; for convulsions 22:523 Hoye's 1:672 of (+)-3,3-dibromocamphor 16:135 of levoglucosenone 14:269 with NBS 19:314 Hoye's bromination 1:678 Hoye's procedure 6:56,57 HPA 25:46 y-HPKC 25:61 HPLC 4:283 anion exchange 4:283 for oligonucleotide purification 4:283 of diastereomers 13:280-282 oftryptic peptides 2:34 reversed phase 4:283 HPLC chromatogram 23:748,751,759, 760 ofLollo rosso 23:759 of lemon juice phenolics 23:748 of red lettuce anthocyanins 23:760 of red onoin anthocyanins 23:762 of Romaine lettuce phenols 23:761 of spinach phenols 23:765 of tomato peel phenolics 23:766 m-HPPA 25:925,927 (5Z,8E)-3-Hptyl-5-methylpyrrolizidine 6:445,446 from 3-(5-methyl-2-furyl) propional-dehyde 6:445,446 HREIMS 30:582,584,586,587 of (-)-6'-hydroxyyatein 30:587 of (-)-hernone 30:587 of (+)-N-formylovigerine 30:582 of (7R,8S,7'R,8'R)-(+)-7'-acetyl5 '-methoxypicropodophyllin 30:586 of 7-formyldehydroovigerine 30:581
390
of ernamymphine 30:582 of ovihernangerine 30:584 HRFAB-MS 26:20,33 ofbisdesmoside 26:41 of dianchinenoside E 26:33 of SAPO 26:30,50,41 of saponarioside A 26:20 HRMS 21:584,734 HRP II inhibition 25:336 HRP II mediated hemozoin synthesis assays 25:352 HRV inhibitors 30:407 in vitro 30:407 from Stevia rebaudiana 30:407 HRV replication inhibitor 30:407 in vitro 30:407 mechanism of 30:407 HSV infections 30:401 acyclovir-resistance in 30:401 antiviral medications for 30:401 symptoms of 30:401 HSV-1 24:524;30:402,403 activity of actinoplanic acids against 24:524 antiviral activity against 30:403 in vivo 30:403 inhibitor of 30:402 HSV-1 corneal infection 21:697 therapeutic efficacy against 21:697 HSV- 1 infection 21:694 HSV-1 replication 21:695 inhibitory effect on 21:695 HSV-2 30:402,403 in vitro 30:402 inhibitors of 30:402 HSV-2-virus 4:237;19:289 antiviral activity against 4:237 Co-3-human colon carcinoma 19:289 HT-29 (human colon carcinoma) 30:588,691 activity of (-)-deoxypodophyllotoxin against 30:588 activity of (-)-yatein against 30:588 phenolic triterpenes against 30:691 5-HT3 class receptors 25:529
5-HT3 receptor 27:286 5-HT4 receptor 27:286 Huang-Minlon modification 14:684 Huang-Minlon reduction 14:674,676, 677 Huangqioside E 27:18,35 structure of 27:35 Huangqmyegenin 25:1 25:195 Huangqmyegenin A 25:195 Huangqulyegenin B 25:202 Huangqmyegenin II 25:202 Huangqmyenin 25:184 Huangqmyenin D 25:192 Hudson lactone rule 10:262 Hugonia 26:172 Huiliste 22:560 Huisgen pyrrole synthesis 13:445 Human breast cancer cell line MCF-7 30:314 human cancer cell lines 30:589,590 activity of (-)-deoxypodophyllotoxin in 30:589 activity of (-)-hernone in 30:590 activity of (-)-nymphone in 30:590 activity of (-)-yatein in 30:590 activity of (+)-corytuberine in 30:589 actwity of (+)-epiaschantin in 30:590 actwlty of (+)-epimagnolin in 30:590 actwlty of (+)-epiyangambin in 30:590 actwlty of (+)-hernovine in 30:589 actwlty of (+)-laurotetanine in 30:589 actwlty of (+)-magnoflorine in 30:589 activity of (+)-malekulatine in 30:590 activity of (+)-N- activity of hydroxyhernangerine in 30:589 activity of (+)-N- formylnornantenine in 30:589 activity of (+)-N-formyldehydroovigerine in 30:589
391
activity of (+)-N-formylovigerine in 30:589 activity of (+)-ovigerine in 30:590 activity of (+)-ovihernangerine in 30:590 activity of (+)-vateamine-2'~-Noxide in 30:590 activity of 7-formyldehydrohemangerine in 30:589 activity of 7-formyldehydronornantenine in 30:589 activity of 7-formyldehydroovigerine in 30:589 activity of 7-hydroxy-6-methoxy1-methylisoquinoline in 30:589 activity of 7-oxohernagine in 30:590 activity of demethylsonodione in 30:589 activity of hernandonine in 30:589 activity of hernanymphine in 30:589 activity of N-hydroxyovigerine in 30:589 activity of N-methylcorydaldine in 30:589 activity of N-methylovigerine in 30:590 activity ofthalifoline in 30:590 Human carcinoma 24:6 of nasopharynx (KB) 24:6 Human chemopreventives 30:592 Human colon adenocarcinoma cell cultures 25:903 Human colon carcinoma 23:255,290 Human cytomegalovirus 30:395 inhibitor of 30:395 Human cytomegalovirus (HCMV) 21:646 Human cytomegalovirus protease inhibitors 28:118 bripiodionen as 28:117,118 Human diseases 30:224 aging 30:224 atherosclerosis 30:224 cancer 30:224 cardiac diseases 30:224
diabetes inflammation 30:224 intestinal diseases 30:224 neurodegeneration 30:224 reperfusion injuries 30:224 respiratory disorders 30:224 role of free radicals in 30:224 Human growth hormone 4:271 Human HEK 293 cell line 30:781 biological response of 30:781 Human HL-60 leukemia cells 30:496 differentiation of 30:496 inhibition of 30:496 proliferation of 30:496 Human IgG! Hinge-fragment 18:907-958 Human immunodeficiency virus 7:12, 396;21:149;26:223 ;30:226,395,396, 412 inhibitor of 30:395 Human immunodeficiency virus type-1 25:948 Human interleukin-[3 21:404 Human leucocyte elastase 25:47 inhibition of 25:47 Human leukemia cells 18:269 Human leukocyte elastase 16:727 inhibitor of 16:727 Human leukocyte elastase (HLE) 30:830,831,843 homologous sequences of 30:831 plasminogen activator (u-PA) 30:830 Human lung carcinoma 23:290;30:5 discodermolide against 30:5 A-549(Human lung carcinoma) 30:691 phenolic triterpenes against 30:691 Human medulloblastoma 23:290 Human melanoma 23:255 Human mesangial cell proliferation 30:308 in vitro 30:308 Human monoblastic leukemia cells 30:498 effect of hydroxyurea (HU) 30:498 growth inhibition of 30:498
392
Human monoblastic leukemia U937 cells 30:498 growth inhibition of 30:498 Human nasopharyngeal KB 12:390 staurosporine activity against 12:390 Human neuroblastoma NB- 1 cells 12:390 cytotoxic against staurosporine 12:390 Human neuroblastoma nbla-N-5 cells tamoxifen activity against 12:390 Human neuroblastoma SH-SY-5Y cells 12:390 Human neutrophils 12:390 Human neutropil protein kinase C 12:389 Human onchocerciasis 12:9 ivermectin for 12:9 Human papilloma virus 23:97;26:223; 30:394 pathogenesis of 30:394 cause of hepatocellular carcinoma 30:394 Human papilloma virus type 11 30:406 microbicidal compound against 30:406 Human papilloma virus type 40 30:406 microbicidal compound against 30:406 Human platelets 12:390 study of protein kinase C in 12:390 by staurosporine 12:390 Human rotavirus (HRV) 30:406,412 cause of dehydrating gastroenteritis 30:406 member of 30:406 reoviridae type of 30:406 Human serotonin transporter gene (SLC6A4) 30:376 regulation of neuronal activity 30:376 Human spermatozoa motility 21:675 Human synovial PLA2 25:697 inhibitor of 25:697 Human xenografted carcinomas 19:330
Humantenine 15:472 from Gelsemium elegans 15:472 Humantenine-type oxindole alkaloids 15:472-474 Humantenirine 9:196,197;15:472 Humboldlia vahliana 22:523 use for epilepsy 22:523 Humicola spp. 2:323 et-Humulene 21:586,594 Humulene 3:77,78;6:37,48;13:6;23:545, 852;25:168,170 (+)-africanol from 6:37 (+)-A9~12)-capnellene from 6:48 c~-Humulene epoxide 21:586 Humulones 23:342,348;24:902-904 anti-glycemic effects 24:902-904 anti-hyperglycemic effects of 24:902-904 Humulus lupulus 7:121;14:450;21:521, 584 ;23:342 ;24:902 [3-farnesene from 7:121 eudesm- 11-en-4-ols from 14:450 (-)-selin-11-en-4a-ol from 14:450 Hunnemannia genera 27:163 Hunteria 13:70,93 indole alkaloids 13:70,93 2-Huoro-ABA 27:355 Hup A 21:748-750 clinical trials of 21:750 Huperzia serrata 21:744 (+)-Huperzine A 18:321,324 Huperzine A 21:746-748;22:30 synthesis of 21:746-748 Huperzine B 21:748 Hura crepitans 20:19 Huratoxin 20:19 Hv-CPI phytocystatin 29:593 effects on chymopapain 29:593 effects on ficin papain 29:593 Hyalbidone 17:400 Hyalodendron pyrium 5:305 Hyalodendron sp. 5:305;21:218 Hyalomma anatolicum 28:405 Hyalomma genera 28:404 Hyalomma sp. 28:396,407 Hyalophora cecropia 1:206;22:381 Hyalurnidase-inhibitory activity 25:939
393
Hyaluronidase 25:939 Hyattella 19:568 Hybrimycins 5:615 Hydalhodes 25:391 Hyderabadine 5:124,158 Hydnellum (Hydnum) 29:271 Hydnocarpin 5:496 Hydnocarpus wightiana 5:496 Hydnum suaveolens 29:284 Hydoxybenzoic acid 22:630 pHydractinia echinata 18:701 Hydrangea macrophylla 2:286;13:660; 15:5,30,387;27:7,17 phylloduclin from 13:660;15:30 Hydrangea macrophylla Seringe var. thunbergii 27:17 Hydrangenol 2:288,289,387 Hydrangenol glucoside 2:288,289 a-Hydrastine 1:191,192 synthesis of 1:191,192 Hydrastine 21:69 (-)13-Hydrastine 26:868 (+)[3-Hydrastine 26:868 [3-Hydrastine 1:191,192 synthesis of 1:191,192 13-Hydrastine N-oxide 6:468 1,2-H shift in 6:468 thermally-induced rearrangement of 6:468 Hydration 4:332 mercury catalysed 4:332 of acetylenes 4:332 Hydrato-pyrrhoxanthinol 6:151,152 Hydrazine 1:20 reduction with 1:20 Hydrazine acetate 21:168 Hydrazinolysis 25:438 Hydrazoic acid 22:283 Hydrazone 18:67 Hydrellia sp. 22:401 1,4-Hydride reduction 12:154 Hydride reduction 14:153;19:372 of sulfonates 14:153 [ 1,2]-Hydride shift 10:216,222;19:518 Hydride shift 9:45,46 2,6-Hydride shifts 4:626,627,634,643 in camphor derivative 4:634,643
in rearrangement of camphor 4:626,627 Hydride transfer 17:486-487 6,2-Hydride-shift 4:650,651 trans-Hydrindane 10:51 synthesis of 10:51 Hydrindane 13:24 trans-Hydrindane system 14:552 cis-Hydrindane system 9:526 Hydrindanol 10:55,56 Hydrindanone 9:249-252;10:51,56 in (+)-9-isocyanopupukenanane 6:80 Hydroalanation 10:21,24,29 cis-Hydroazulene 12:251 from tropone 12:251 Hydroazulene mesylates 14:376-379 Hydroazulene sesquiterpenes 14:355-387 Hydroazulene skeleton 1:553 synthesis of 1:553 Hydroazulenes 10:181 Hydroboration 8:470-473,475,478; 10:15;11:83,84,316,317,319;14:456, 681,682;16:472;19:367 highly stereoselective 12:151, 152 of allylic ethers 4:116 of olefin 12:151,152 of vinylic ethers 4:116 regioselectivity 4:116 stereoselective 19:367 to alcohol 12:151,152 Hydroboration-oxidation 14:773,774; 24:203,204,210 Hydrocarbons 27:700 from olive oil 27:700 Hydrochalcones 7:192 Hydrocholeretic effect 26:391,399,415 Hydrocortisone 9:17,411,416,418-423, 428,429;22:122,123 ;25:56,57 e~-acetate 9:17,416 Hydrocotile genera 27:661 Hydrocotyloideae 27:661 Hydrodictyon reticulatum 18:495,507; 19:247 Hydrodicyclopenta [a,d] cyclooctane 1:563-565 Hydroformylation 16:409
394
Hydrogen abstraction 16:41 Hydrogen bonding 17:562 Hydrogen peroxide oxidation 14:324, 325 Hydrogen phosphonate method 4:274-276 of oligonucleotide synthesis 4:274-276 mechanism of 4:275 1,5-Hydrogen shift 1:327 A~-Hydrogenase activity 9:420 stereoselective 16:345 ofazide group 16:78 Hydrogenation 24:36,37,100,101,104, 119,182;30:486 2,3-anti selective 12:35,36 heterogenous 12:36 homogenous 12:35,36 of double bond 19:45;19:307 ofketones 19:27 of methyl acetoacetate 13:72,73 of phenyl sulfone derivative 30:486 of pyranone 19:468 of [3-ketoester 19:29 on naphthalene-Cr (CO)3 complex 4:343,344 stereoselective 12:151,152; 19:296,301 using Adam's catalyst 19:70 1-Hydrogenation 26:66 of 10,13-dimethyl-9-tetradecenol 26:66 Hydrogen-bonding 30:581 of 7-formyldehydroovigerine 30:581 Hydrogenocobyrinic acid 9:601 Hydrogenolysis 6:276,426,435,451,168, 169; 19:6,36,38,42,104,332,362, 367-368,371 ;21:200;30:17 of PMB group 30:17 Hydrogenomonas eutropha 4:439 Hydroindane (bicyclo [4.3.0] nonane) 11:230 Hydroindanone 19:10 cisHydroindolenones 4:17-19 from a'-bromocyclohexenones 4:17-19
Hydrolapachol (2-hydroxy- 1,4naphthoquinone) 26:803 Hydrolysable tannins 23:750;27:840 activity of 27:840 Hydrolysis 1:678,679,682;27:354 asymmetric 1:678,679,682 by Candida cylindracea lipase 1:685 by lipases 1:684,685 by pig liver esterase 1:685 by pig pancreatic lipase 1:685 by Pseudomonas fluorescens lipase 1:685 ofabscisic acid-GE 27:354 of fat 27:402 of N-acetyl (x-amino acids 1:678,679,684,685 acid-catalyzed 11:361 enantioselective 13:54 ofabscisic acid-GE 27:354 of fat 27:402 of phosphate 27:872 photochemical 6:331,333 selective 6:285,286 Hydrolysis products 27:82 of epoxyaldehydes 27:82 Hydrolytic cleavage 12:428-430 Hydrolytic fragmentation 12:198 Hydrolyzable tannins 25:541 Hydronaphthalene 22:253 Hydronaphthalene tosylates 14:368-370 Hydronaphthalene- 1,10-diol monosulfonate esters 14:356 Pinacol rearrangement of 14:356 Hydroperoxide 17:9 R-Hydroperoxide 9:574 Hydroperoxide initiated 22:346 chemiluminescence 22:346 Hydroperoxide dehydrase 9:526,577 Hydroperoxide isomerases 9:577,578 Hydroperoxide lyase 9:577;13:11 Hydroperoxide oxidation 4:559 Hydroperoxides 5:409;16:608 cyctotoxic activity of 5:409 photodecomposition of 16:608 9/13-Hydroperoxo-),-linolenic acids 9:582
395
10-epi-5~-Hydroperoxy-[3-eudesmol 23:811 16-Hydroperoxy-10,12,14-octadecatrienoic acid 27:71 generation of 27:71 9-Hydroperoxy- 10,12,15-octadecatrienoic acid 27:74 by Baeyer-Villiger reaction 27:94 transformation of 27:74 (6S, 7S, 10R)-2-Hydroperoxy-2,6,10trimethyl-7,10-epoxydodeca-3,11dien-5-one 27:594 24-Hydroperoxy-24-vinyl-cholesterol (saringosterol) 10:249 2E-4-Hydroperoxy-2-nonenal (4-HNE) 27:74,75,83 generation of 27:75 25-Hydroperoxy-2c~,313,12~,20Stetrahydroxydammar-23-ene 18:650 5-Hydroperoxy-6,8,11,14-eicosatetraenoic acid (5-HPETE) 5:513,514 13S-Hydroperoxy-9Z, 11E-octadecadienoate 9:563,565 13R-Hydroperoxy-9Z, 12E-octadecadienoate 9:566 13-Hydroperoxy-9Z- 11E-octadecaenoic acid 27:69-71 generation of 27:69,70 Hydroperoxycadiforin 22:653,654; 30:611,612 structure of 30:612 5-Hydroperoxy-eicosatetraenoic acid 26:265 5S-Hydroperoxy-icsatetraenoic acid 9:562 Hydrophobic metabolites 27:447,484 Hydrophobicity 27:333 Hydroprene 10:149;22:395 1,4-Hydroquinone 23:53 Hydroquinone 5:439,440;9:579;25:658 Hydrothermolysis 26:40 Hydroxamates 9:537,580 Hydroxamic acid 1:296;9:549 (S)-Hydroxamic acid 19:11 (4S)-Hydroxmethylbutanolide 6:292 from L-glutamic acid 6:292 from D-ribonolactone 6:292
13-Hydroxy 3or,11-epoxy-apotrichothec9-ene 9:210 c~-Hydroxy acids 1:446,447 as chiral building blocks 1:680,681 3-Hydroxy acids 4:625 as chiral synthons 4:625 ent -8c~-Hydroxy- 13,14-dien- 18-oic acid methyl ester 25:261 w-Hydroxy acids 8:176,233,234,236 cyclization of 8:234 intramolecular esterification of 8:176 lactonization of 8:233,234,236 Hydroxy amino acids 12:431-438 synthesis of 12:431-438 c0-Hydroxy Ct4 30:145 synthesis of 30:145 (R)-2-Hydroxy carboxylates 20:840-842,853 dehydrogenation of 20:840-842 to 2-oxo-carboxylates 20:840-842,853 preparation of 20:842 Hydroxy cinnamoyl-CoA esters 25:652 8-Hydroxy citronellol 25:136 N-Hydroxy compounds 8:376 cis,cis-2c~-Hydroxy costunolide 27:560 3~-Hydroxy costunolide 27:560 7-Hydroxy coumarin 23:337 Hydroxy dithioketal 10:203,204 trans-Hydroxy epoxide 10:205,206 cyclization of 10:205,206 Hydroxy epoxides 10:205-207 cis-Hydroxy epoxides 10:207 [3-Hydroxy ester 1:689-701 as chiral building blocks 1:689-701 from (a-bromoalkyl) boronic ester 11:425 synthesis of 11:425 2-(1-Hydroxy ethyl)-naptho [2,3-b] furan-4,9-dione 20:494 14-Hydroxy ferruginol 20:666 from Salvia montbretii 20:666 3-Hydroxy flavanones 23:798 4,5-cis-3 [3-Hydroxy germacranolide 27:561
396 2-Hydroxy glycal 10:349 4-Hydroxy isopiperitenone 25:151 [3-Hydroxy ketones 1:701-707 Hydroxy ketones 10:205 syn selectivity of 10:205 13-Hydroxy lactone 12:29,30 10-Hydroxy liriodenine 20:483 Hydroxy methylglutarylcoenzyme A synthetase 25:525 2-Hydroxy muconate 10:152 7-Hydroxy muurollene 21:282 4-Hydroxy N-(3,7-octaienly) oxazolidin2-one 12:468 10-Hydroxy octadec-(8E)-enoic acid 13:313 13-Hydroxy octadeca-(9Z, 11E)-dienoic acid 13:311 11-Hydroxy palmitic acid 13:312 Hydroxy pyrrolidinone carboxylate 8:269 713-Hydroxy sandracopimaric acid 20:690 from Salvia heldrichiana 20:690 3fl-Hydroxy sterols ~25:306 16-o~-Hydroxy tubeimoside I 21:732 25-Hydroxy vitamin D2 10:63,65,66, 68,69 synthesis of 10:69 25E,26-Hydroxy vitamin D2 10:65 (24R)- 1ot-Hydroxy vitamin D2 10:66 1a-Hydroxy vitamin D3 10:43,59,69 synthesis of 10:59,69 25-Hydroxy vitamin D3 10:67 4[3-Hydroxy withanolide E 20:214,245 17[3-Hydroxy withanolide K 20:246 16a-Hydroxy-(-)-kauronoic acid 9:397 15-(2-Hydroxy)-isobutyryloxy-micrantholide 29:89 activity in TNFct assay system 29:89 3-(Hydroxy)methylene-2-thioxopyrrolidine (HMTP) 26:1073,1077-1079, 1083,1084,1087,1092,1093,1095, 1096,1099,1100,1102,1103 3fl-Hydroxy[6a-acetoxy,23-ethoxy, 16fl, 23(R) epoxy-24,25,26,27-tetranor]9fl,19-cyclolanostane 25:185
20S-Hydroxy- 1,2-dehydropseudoaspidospermidine 5:126;9:195 4-Hydroxy- 1,2-dithiolane 7:193,194 5-Hydroxy- 1,4-naphthoquinone 14:49 2-Hydroxy- 1,4-naphthoquione 26:804 1[3-Hydroxy-10,14-dehydro- 1,10Hparthenolide 27:566 6-Hydroxy- 10-formamido- 15-isothiocyano-kalihinene 25:856 11-Hydroxy- 10-methoxynoracronycine 13:348,349 from Citrus decumna 13:348,349 (E)-trans- 1-Hydroxy- 10-vinyl-2cyclodecene 8:196 synthesis of 8:196 (Z)-trans- 1-Hydroxy- 10-vinyl-2cyclodecene 8:196 synthesis of 8:196 6et-Hydroxy- 11,13-dihydro-5,7ctH,8, 11~H-eudesm-4(15)-en-8,12-olide 27:552 1-Hydroxy- 11-methoxycanthin-6-one 7:389,390 12-Hydroxy- 11-methoxydiaboline 9:189 10-Hydroxy- 11-methoxydracaenone 5:17-20 12-Hydroxy- 11-methoxyhenningsamine 9:27 12-Hydroxy- 11-methoxy-N-acetyl-norC-fluorocurarimine 26:1052,1053 12-Hydroxy- 11-methoxy-nor-Cflourocurarine 26:1052 19-Hydroxy- 11-methoxytabersonine 2:375 10-Hydroxy- 11-methoxytabersonine 5:128 6-Hydroxy-12-tridecene 9:241,243 3[3-Hydroxy-13,14,15,16-tetranorlabda7,9( 11)-dien-( 19,613),(12,17)-diolide 28:508 synthesis of 28:508 Ent- 16-Hydroxy- 13[R]-pimar-8( 14)ene-3,15-dione 9:283-287,290 Ent- 13[S]-Hydroxy- 14-oxo-3,4-secoatis-16-en-3,4-olide 9:268,269,276 14-Hydroxy- 15-isovaleroyloxy-9-oxomelampolide 29:89
397 activity in NFkB assay system 29:89 Hydroxy- 15[3-aristoline 9:172 16 (S)-Hydroxy-16,17-dihydroapparicine 6:505,506 16S-Hydroxy- 16,22-dihydroapparicine 5:124 16S-Hydroxy- 16,22-dihydroapparicine 9:171,172 3fl,7a 22-Hydroxy- 16,23-epoxy-24,25, 26,27-tetranor-9fl, 19-cyclolanostane 25:184 3R/S-Hydroxy- 16-decarbomethoxyconodurine 5:125 10-Hydroxy-16-epi-affinine 5:124 19(R)-Hydroxy- 18,19-dihydrokoumine 15:476,477 19(S)-Hydroxy- 18,19-dihydrokoumine 15:476 from Gelsemium elegans 15:476 X-ray analysis of 15:477 18-Hydroxy- 19(Z)- anhydrovobasinediol 15:500 Hydroxy- 1-arylthiobutenes 4:477,478 cycloaddition with 4:477,478 1c~-Hydroxy-1-desoxoarglamine 27:549 1c~-Hydroxy-1-desoxochrysanolide 27:559 1[3-Hydroxy- 1-desoxochrysanolide 27:559 lct-Hydroxy- 1-desoxo-tamirin 27:568 1~-Hydroxy- 1-desoxo-tamirin 27:568 11-Hydroxy- 1-methoxycanthin-6-one 7:389,390 1-Hydroxy- 1-methylindolizidines 12:282 4-Hydroxy- 1-oxo- 1,2,3,4-tetrahydronaphthalene 11:118 1-Hydroxy- 1-phenylindolizidines 12:282 E-(3-Hydroxy- 1-propenyl)[3-Dglucopyranosetetraacetate 10:422 (6S*,7S*, 10R*)-3-Hydroxy-2,10,10trimethyl-7,10-epoxy-dodeca- 1,11dien-5-one 27:594 13-Hydroxy-2,15-diacetoxy- 11-epiapotrichothec-9-ene 9:210
23-Hydroxy-2,16-dehydroretuline 1:38,39;9:186 Cis (3 S, 5R)-2-Hydroxy-2,2,6-trimethyltetrahydropyran 25:143 (4R,6R)-4-H ydro xy-2,2,6-trime thylcyclohexanone 6:143,144,158 synthesis of 6:158 3-Hydroxy-2,2,6-trimethyltetrahydropyran 25:144 6-Hydroxy-2,2-dimethyl chromene 10:248 (4S)-4-Hydroxy-2,6,6-trimethyl-2cyclohexen-l-one 6:159 synthesis of 6:159 7-Hydroxy-2 '-metho xy-4 '5 '-methylenedioxyisoflavan 256 27:499 structure 27:473 of 25-Hydroxy-20,24-epoxy 27:473 3 [3-Hydroxy-20 -methoxy-30-norolean12-en-28-oic acid 7:139,140 21 ct-Hydroxy-20,22-dioxo-30(20~21) abeo-21-desoxotingenone 30:670 13C-NMR of 30:670 HMBC of 30:670 molecular formula of 30:670 MS of 30:670 NOE of 30:670 (15R)- 15'-Hydroxy-20'-deoxyvinblastine 14:814,815 acetyl derivative of 14:814,815 from 20'deoxy- 15 '-oxovinblastine 14:814,815
19R-Hydroxy-20-epi-ibophyllidine 5:127
19S-Hydroxy-20-epi-ibophyllidine 5:127;9:190,192
18-Hydroxy-20-epi-ibophyllidine 9:190 19R-Hydroxy-20-epi-ibophyllidine 9:190
(+)-19-Hydroxy-20-epi-pandoline 5:124 19-Hydroxy-20-epipandoline 9:190
20-Hydroxy-22-oxo-20-epi-tingenone 30:670 13C-NMR of 30:670 HMBC of 30:670 molecular formula of 30:670 MS of 30:670 NOE of 30:670
398
20-Hydroxy-22-oxotingenone 30:670 13C-NMR of 30:670 HMBC of 30:670 molecular formula of 30:670 MS of 30:670 NOE of 30:670 25-Hydroxy-24-epicastasterone 18:529 26-Hydroxy-24-epicastasterone 18:529 1cx-Hydroxy-25-oxa-25-phosphavitamin D3 9:520 4-Hydroxy-2-cyclopentenone acetal from meso-3,4-epoxycyclopentanone 14:510 8-Hydroxy-2'-deoxyguanosine 26:253 (+)-1-Hydroxy-2-epi-pinoresinol 5:538 (3S)-3-Hydroxy-2-ethyl-butyronitriles 13:59 3-Hydroxy-2-hydroxymethyl pyrrolidine 14:570 hydrochloride 14:570 from pyrrolidine derivative 14:570 3-Hydroxy-2-hydroxymethyl-6substituted piperidines 12:474 1-Hydroxy-2-hydroxymethylanthraquinone 26:660 9-Hydroxy-2-methyl ellipticine 22:9 1-Hydroxy-2-methyl-anthraquinone 26:660 7-Hydroxy-2-methyl-anthraquinone 26:676 Hydroxy-2-methylantraquinone 26:676 12-Hydroxy-2-methyldodecanal 26:70 wittig reaction of 26:70 (R)-3-Hydroxy-2-methylpropionate 6:292,293 (S)-5-Hydroxy-2-penten-4-olide 14:273,274 from levoglucosenone 14:273, 274 4-Hydroxy-2-pyridone chromophore 21:215 2-Hydroxy-3-(2-methoxyphenyl) propenoic acids 30:222 cyclisation of 30:222 7-Hydroxy-3-(3-hydroxy-4methoxybenzyl) chromane 5:20-22 13-Hydroxy-3,11-epoxy APO 13:522
(20R)-Hydroxy-3,24-diepibrassinolide 18:531 25-Hydroxy-3,24-diepibrassinolide 18:532 (20R)-Hydroxy-3,24-diepicastasteron 18:531,539,542 8-Hydroxy-3,4-dihydroisocoumarin 15:384 7-Hydroxy-3,4-epoxy-laurane (laurol) 9:193,194,199 6-Hydroxy-3,5,9,11-tetraoxodo-decanedioate 11:118 from c~-hydroxyglutarate 11:118 (E)-6-H ydroxy-3,7-dimethyl-2,7ocatdienyl xanthoangelol B 30:76 1-Hydroxy-3,7-dimethyl- 6- octen- 2- one 25:133 (+)-(4'-Hydroxy-3'-methoxycinnamoyl)-epil-upinine 27:268 3-Hydroxy-30-norolean- 12,19-dien-28oic acid 7:139,140 3 [3-Hydroxy-30-nor-olean- 12,20(29)dien-28-oic-acid 9:51 ent-8c~-Hydroxy-labda-13 (16), 14-diene 25:273,274 19'S-Hydroxy-3-epi-ervafolidine 5:129 2-Hydroxy-3-methoxy strychnine 26:1030,1052 2213-Hydroxy-3-methoxy-6-oxotingenol 30:680,681 ~H-NMR spectrum of 30:680 molecular formula of 30:680,681 ROESY experiment of 30:681 structure of 30:681 3,4-bis(4-Hydroxy-3-methoxy-benzyl) tetrahydrofuran 26:255 1-Hydroxy-3-methoxyxanthone 25:467 2-Hydroxy-3-methoxyxanthone 5:759 (-)-8-Hydroxy-3-methyl-3,4-dihydroisocumarin 15:383 3-Hydroxy-3-methylglutaryl CoA 25:130 3-Hydroxy-3-methylglutarate 21:634 S-3-Hydroxy-3-methylglutaryl 27:383 3-Hydroxy-3-methyl-glutaryl coenzyme A reductase 11:335
399 3-Hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase 24:351-398 fungal metabolism of 24:361,362 in metabolism 24:359-361 regulation of 24:361,362 3-Hydroxy-3-methylglutarylcoenzyme 27:386 22[~-Hydroxy-3-oxo- 12-ursen-30-oic acid 30:654 ~3C NMR spectrum of 30:654 stereochemistry of 30:654 28-Hydroxy-3-oxo- 12-ursen-30-oic acid 30:654 ~3C NMR spectrum of 30:654 2D NMR spectral analysis of 30:654 7-Hydroxy-3-oxoindolizidine 12:287, 288 synthesis of 12:287,288 15'-Hydroxy-3'-oxoleurosidine 14:812, 813 from anhydrovinblastine N-oxide 14:812,813 28-Hydroxy-3-oxo-olean- 12-en-29-oic acid 30:649 2D NMR spectroscopic of 30:649 17-Hydroxy-3-oxotabersonine 4:58,59 reaction with nitrogen nucleophiles 4:58,59 reaction with sulfur nucleophiles 4:58,59
N-2-Hydroxy-3-trans-octadecenoyl- 1-
O-D-glucosyl-9-methyl-cis-4,8sphingadienine 18:807 8-Hydroxy-3-undecyl-3,4dihydroisocoumarin 15:386 2-Hydroxy-4-(O-prenyl)-benzaldehyde 21:742 3 [3-Hydroxy-4,4,14-trimethylpregna9(11), 16-diene-20-one 7:279 Ent- 13 [S]-Hydroxy-4,5-oxy-4,5-oxy4,5-seco-atis- 16-ene-3,14-dione 9:268,269,276 1'-Hydroxy-4'-oxo-c~-ionone 27:330 6-Hydroxy-4a-aryl-cis-decahydroisoquinolines 12:458,459
synthesis of 12:458,459 6-Hydroxy-4a-aryl-transdecahydroisoquinolines 12:457 3-Hydroxy-4-alkoxy substitution 15:30 6'-Hydroxy-4'-methoxyavarone 15:301 2-Hydroxy-4-methyl acetophenone 23:165 (+)-5-Hydroxy-4-oxonorvaline(+)HON 13:512,513 5-Hydroxy-4-oxyindolizidines 12:284 3-Hydroxy-4-pentenyl amines 14:568 stereoselective cyclization of 14:568 to pyrrolidines 14:568 6-Hydroxy-4ot-phenyldecahydro 12:457 from 6-hydroxy-4a-aryl-transdecahydroisoquinoline 12:457 11-Hydroxy-5,14-diacetoxy-9,10dehydrofarnesol acetate 27:586 6c~-Hydroxy-5,7~H,8[3H-eudesm-4( 15)en-8,12-olide 27:552 6'-Hydroxy-5'-acetyl-avarol 15:301 6-Hydroxy-5-methylmellein 9:288,289 5-Hydroxy-5-vinyl-2-cyclopenten- 1ones 14:625 2-Hydroxy-6-(2-oxoheptyl) benzoic acid 9:328 (E)- 10-Hydroxy-6,10-dimethyl-5undecen-2-one 25:168 5-Hydroxy-6,7,3',4',5'-pentamethoxyflavone 5:756,757 5-Hydroxy-6,7,4-trimethoxyflavone 5:653 5-H ydroxy-6,7,8,4'-tetramethoxyflavone 5:653 5-H ydroxy-6,7,8-trimethoxyflavo ne 5:652 5-Hydroxy-6,7-dimethoxyflavone 5:652
12-Hydroxy-6,7-seco-abieta-8,11,13-
trien-6,7-dial 29:99 activity in EBV assay system 29:99 2-Hydroxy-6-[(Z)-heptadec-8-enyl] benzoic acid 9:316 4[3-Hydroxy-6-deoxy-6-deoxycelorbicol 18:743 (+)- 1-Hydroxy-6-epi-pinoresinol 5:538, 540,541
400
7-Hydroxy-6-methoxy- 1-methylisoquinoline 30:564,589 activity in human cancer cell line 30:589 cytotoxic effect of 30:589 7-Hydroxy-6-methoxycoumarin 9:288, 289 2-Hydroxy-6-methylbenzoic acid 9:341, 347,350 7-Hydroxy-6-methylhept-5-en-2-one 25:138 7-Hydroxy-6-methylhept-5-ene-2-one- 1ol 25:136 7-Hydroxy-6-methylheptan-2-one 25:138 5-Hydroxy-6-oxo-coronaridine 5:127 23-nor-22f3-Hydroxy-6-oxotingenol 30:680 13C-NMR of 30:680 DEPT of 30:680 1H-NMR spectrum of 30:680 HMBC experiment of 30:680 molecular formula of 30:680 2-Hydroxy-6-pentadecylbenzoic acid (15:0-anacardic acid) 9:336,345, 346,372 2-Hydroxy-6-tetradecylbenzoic acid 9:317 2-Hydroxy-6-undecylbenzoic acid (anagigantic acid) 9:316 1J3-Hydroxy-6c~-angeloyl-oxyeudesm4(15), 1l(13)-dien-8,12-olide 27:552 1~-Hydroxy-6c~-angeloyl-oxygermacra4(5), 10(14), 1l(13)-trien-8,12-olide 27:561 (2 S,6S)-2 ~-Hydroxy-613-acetoxynortropane 21:751 2213-Hydroxy- 7,8- dihydro- 6-oxotinge no 1 30:681 IH-NMR spectrum of 30:681 molecular formula of 30:681 5-Hydroxy-7,8-dimethoxyflavone 5:640 4-Hydroxy-7[ I -hydroxy-7-[ 1-hydroxy2-methylamino)ethyl]-l,3-benzothiazole-2(3H)-one 25:896
( 1R*,3S*,4R*,7 S*, 8S, 12R*, 13R*)- 12Hydroxy-7-isothiocyanatoamphilecta-1 l(20),14-dlene 25:853 1-Hydroxy-7-methoxyxanthone 5:759 7-Hydroxy-7-methyl-5-oxoindolizidine 12:289 configuration of 12:289 synthesis of 12:289 7-Hydroxy-7-phenylindolizidines 12:286 8a-Hydroxy-7ct(H)-eremophila- 1,11diene-9-one 15:242 ent- 16-Hydroxy- 13-epi-manoyl oxide 25:250 ent- 19-Hydroxy- 13-epi-manoyl oxide 25:253 ent-3a-Hydroxy- 13-epi-manoyl oxide 25:250 ent-3fl-Hydroxy- 13-epi-manoyl oxide 25:253,254,267,263 Hydroxy-8-methoxyflavonoid 5:64062-Hydroxy-8-p-mehthen-7-oic acid 25:149 9c~-Hydroxy-813-methacryloyloxy- 14oxo-acanthopsermolide-4a,5 [3epoxide 29:89 activity in NFkB assay system 29:89 ent-4ot-Hydroxy- 19-nor-Beyer- 15-ene 30:714 structure of 30:714 7-Hydroxy-9(11)-secogorgosterol 21:312 13-Hydroxy-9,11-octadecadienoic acid 21:197 5-Hydroxy-9-acetoxynerolidol 27:586 8~-Hydroxy-9c~-methacryloyloxy- 14oxo-acanthospermolide 29:89 activity in NFkB assay system 29:89 from Milleria quiqueflora 29:89 Ent- 17-Hydroxyabieta- 8(14), 13( 15)dien-16-al 9:83,284 Ent- 11ot-Hydroxyabieta-8(14),3( 15)dien- 16,12-olide 9:283,284-290 7'-Hydroxyabscisic acid 27:348 8'-Hydroxyabscisic acid 27:345,350 isomerization rates of 27:350
401 ot-Hydroxyacetophenone 21:147 p-Hydroxyacetophenone 21:741;30:731 structure of 30:731 8ot-Hydroxyachillin 27:574 Hydroxyachillin 29:89 activity in TPA assay system 29:89 activity in PKC assay system 29:89 activity in CRG assay system 29:89 1-Hydroxyacridin-9-one (N-methylnoracridin)-9-one 13:348,362,363 11-Hydroxyacronycine 13:357,358,366, 367 [3-Hydroxyacteoside 5:506,509,511, 513,514 2-Hydroxyaklavinone 11:120 12-Hydroxyakuammicine 5:123;9:193 4[3-Hydroxy-alatol 18:747 o~-Hydroxyaldehyde derivatives 6:316,317 synthesis of 6:316,317 oc-Hydroxyaldehydes 6:336,337 synthesis of 6:336,337 [3-Hydroxyalkyl selenides 8:4 from cyclohexanone 2,2,6,6tetramethyl 8:4 from deoxybenzoine 8:4 2,2,6-trimethyl cyclohexanone 8:4 1-(c~-Hydroxyalkyl) isoquinolines 12:449 2-(o~-Hydroxyalkyl) piperidines 12:453 diastereoselective synthesis of 12:453 synthesis of 12:453-456 2-(c~-Hydroxyalkyl) pyrrolidines 12:473 synthesis of 12:473 1-(ot-Hydroxyalkyl)- 1,2,3,4-tetrahydroisoquinolines 12:450 chiral synthesis of 12:450 c~-(ot'-Hydroxyalkyl)-N- heterocycles 12:447 5-Hydroxyalkylbutan-4-olides 3:160-161 synthesis of 3:160-161
(+)- 16-Hydroxy-allo-ibogamine 6:503 biogenesis of 6:503 Hydroxyalpinolide 23:814 6Hydroxyamide 8:231,234 12ot-Hydroxyamorphigenin 27:574 8-Hydroxyanamycins B,O,S,W 9:443 15-Hydroxy-angustilobien A 9:171 8a-Hydroxyanhydroverlotorin 27:572 313-Hydroxyanhydroverlotorin 27:573 18-Hydroxyanhydrovobasinediol 15:503 9-Hydroxyanthracene 11:119 from homophthalate 11:119 synthesis of 11:119 Hydroxyanthracenones 22:580,582 3-Hydroxyanthranilic acid 26:965,966, 978,1015 5-Hydroxyanthranilic acid 26:971 2-Hydroxyanthraquinone 26:659 Hydroxyanthraquinones 22:556,564 (+)-2 ~-Hydroxyaphylline 27:273 4-Hydroxyaporphines 16:510 synthesis of 16:510 1[3-Hydroxyarbusculin A 27:549 8c~-Hydroxyarbusculin A 27:549 2~-Hydroxyartemorin 7:211 from Artemisia hispanica 7:211 2-Hydroxyarylpropenoic acids 30:221 4'-and 5'-Hydroxyasperentin 15:386 Ent- 18-Hydroxyatis- 16-ene-3,14-dione 9:268,269,279 Ent- 13[S]-Hydroxyatis- 16-ene-3,14dione 9:268-276,9:279,280,286, 290 6'-Hydroxyavarol 15:301 3'-Hydroxyavarone 15:301 1-13-Hydroxybaccatin I 11:5 5-Hydroxy-benzoquinone-l-(2'-hydroxy6'-carboxyanil)-4-imide 26:1003 m-Hydroxybenzaldehyde 10:121,125 Hydroxybenzoate 25:660 Hydroxybenzoic acid 25:655,660,661, 922,923,947 Hydroxybenzoic acid derivatives 28:259 benzoic acid as 28:259 gallic acid as 28:259 4-hydroxybenzoic acid as 28:259
402 isovanillic acid as 28:259 protocatechuic acid as 28:259 salicylic acid as 28:259 syringic acid as 28:259 vanillic acid as 28:259 p-Hydroxybenzoic acids 23:750 glucosides of 23:750 ortho-Hydroxybenzyl 21:162 para-Hydroxybenzyl 21:162 p-Hydroxybenzyl isothiocyanate 26:1076 S-(4-Hydroxybenzyl) glutathione 25:820 Hydroxybenzyloxycarbamoyl 21:168 3fl-Hydroxybiformene 25:249 (-)-3-exo-Hydroxyborneol 4:647,648 (-)-5-endo-Hydroxybomeol 4:647,648 (-)-6-exo-Hydroxyborneol 4:647,648 (+)-5-exo-Hydroxyborneol 4:647,648 (+)-5-endo-Hydroxyborneol 4:648 (3R)-3-Hydroxybutanethioate 13:500 boron enolate of 13:500 (R)-3-Hydroxybutanoic acid acetals 1:610 diasteroselective allylation of 1:610 [3-Hydroxybutanoic acid ester 10:410 3-(4-Hydroxybutyl)-5-propylindolizidine 11:253 absolute stereochemistry of 11:253 biological activity of 11:253 synthesis of 11:253-256 (S)-(-)-3-Hydroxybutylate 23:214 (R)-3-Hydroxybutyrate 12:154 (S)-3-Hydroxybutyrate 6:300,301 as chiral precursor 6:300,301 3-Hydroxybutyrates 4:439 anti-products formation 4:439 in thienamycin synthesis 4:431 [3-1actam formation 4:446 lithio dianions of 4:441 3-Hydroxybutyric acid 4:431,438,440, 465,471,479,480 acid chlorides of 4:471 in thienamicin synthesis of 4:438-440 6-Hydroxycalyxin F 26:902
22a-Hydroxycampesterol 25:415,418, 420 conversion of 25:418 endo-3-Hydroxycamphor 4:660 exo-3-Hydroxycamphor 4:660 11-Hydroxycanthin-6-one 7:389,390 11-bromobenzoate of 7:389,390 10-Hydroxycanthine-6-one 7:393 (z-Hydroxycarboxylic acid 8:140 derivatives of 8:140 6a-Hydroxycatasterone 25:424 (15R)-15'-Hydroxycatharinine 14:820, 821 biosynthesis of 14:820,821 from anhydrovinblastine 14:813,814 from leurosine 14:813,814 25-Hydroxy-celapanol 18:744 4f3-Hydroxy-celapanol 18:744 4[3-Hydroxy-celorbicol 18:743 Hydroxychavicol 23:801 Hydroxychloroquine 22:148 25-Hydroxycholesterol 24:352 cytotoxicity effect of 24:352 2-Hydroxychrysophanol 9:400,401 Hydroxycinnamates 25:656 Hydroxycinnamic acid 23:744,771; 25:652,657,666,919,920 derivatives of 23:744 Hydroxycinnamic acid derivatives 23:771;28:260
(-)-(trans-4'-Hydrox y-c innamoyl ) lupinine 15:521
from Luplnus luteus 15:521 25-Hydroxycolecalciferol 9:521 1f3-Hydroxycolecalciferol (alfacalcidol) 9:521 Hydroxy-colorenone 21:281 5-Hydroxyconiferaldehyde 5:470 3-R/S-Hydroxyconoduramine 5:125 3-R/S-Hydroxyconopharyngine 5:128 19R-Hydroxyconopharyngine 5:128 19S-Hydroxyconopharyngine 5:128 3R-Hydroxyconopharyngine 9:174 3-R-Hydroxyconopharynginehydroxyindolenine 5:.128 3S-Hydroxyconopharynginehydroxyindolenine 9:195
403 19-Hydroxycoronaridine 5:126 3-R/S-Hydroxycoronaridine 5:126 10-Hydroxycoronaridine 5:127;9:174 11-Hydroxycoronaridine 5:127;9:174, 176,177 3R-Hydroxycoronaridine 9:171 10-Hydroxycorynanthediol 14:709,710 synthesis of 14:709,710 7-Hydroxycostunolide 29:89 activity in NFkB assay system 29:89 7-Hydroxycoumarin 23:338 3-Hydroxycoumarin 30:220,221,225 antioxidant properties of 30:225 structure of 30:220 7-Hydroxycoumarin (umbelliferone) 9:114 Hydroxycoumarin esculin 26:314 Hydroxycoumarins 26:330 antimicrobial activity of 26:330 (+)-4-Hydroxycrebanine 16:510 synthesis of 16:510 12-Hydroxyculmorins 13:536 15-Hydroxyculmorins 13:536 5-Hydroxyculmorins 13:536 from Fusarium culmorum 13:536 15-Hydroxyculmorons 13:536 313-Hydroxycycloar-25-en-24-one 9:288,289 21-Hydroxycyclolochnerine 13:389 R,S-4-Hydroxycyclopentenones 6:315 absolute configuration 6:315 asymmetric synthesis 6:315 from D,L-tataric acid 6:315 21 a-Hydroxy-D :A-friedo-olean-3-one 7:147,148 20(S)-Hydroxydamaran-3 [3-yl acetate 2:91,92 oxidation with m-CPBA 2:91,92 20(S)-Hydroxydammaran-3-oen 2:94 Hydroxydammarenone-I 23:546 Hydroxydavanone 27:592 10-Hydroxydeacetylakuammiline 9:195 4-Hydroxydecanoic acid 13:308,315 10-Hydroxydecanoic acid 26:65 methanolysis of 26:65
12-Hydroxydehydroabietic acid 29:99 activity in EBV assay system 29:99 4S-Hydroxy-dendrolasin 15:233 4-Hydroxyderricin 30:74,76 effect on catecholamine-induced vasoconstriction 30:74 inhibitory action of 30:76 inhibitory mechanism of 30:74 1~-Hydroxy-desacetylirinol-4c~,5 [3epoxide 27:565 Hydroxydictyodial 5:370 20-Hydroxydihydrocatharanthinic acid lactone 14:815,816 6-Hydroxydihydrochelerythrine 14:773-775 (+)- 16-Hydroxydihydrocleavamine 14:850-853 synthesis of 14:850-853 6-Hydroxydihydrocleavamine 4:291 coupling with vindoline 4:29 16-Hydroxydihydrocleavamine 5:183,184 synthesis of 5:183,184 Hydroxydihydroeremophilone 15:239,241 A3~4)-15-Hydroxydihydroflabellin 27:579 19(S)-Hydroxydihydrogelsemine 15:479 from Gelsemium elegans 15:479 from Gelsemium rankinii 15:479 19(R)-Hydroxydihydrogelsemine 15:481 from Gelsemium rankinii 15:481 from Gelsemium sempervirens 15:481 19(S)-Hydroxydihydrogelsevirine 15:479 19(R)-Hydroxydihydrogelsevirine 15:479 from Gelsemium elegans 15:479 19(S)-Hydroxydihydrokoumine 15:475 (-)-( 10R)-Hydroxydihydroquinine 14:464,465 synthesis of 14:464,465 20-Hydroxydihydrorankinidine 15:472, 473
404 X-ray analysis of 15:472,473 6-Hydroxydihydrosanguinarine 27:173 structure of 27:173 Ent-7 c~-Hydroxydiplophyllolide 2:278,279 Hydroxy-directed epoxidation 12:300 of trifluoracetate salt 12:300 2-Hydroxydiscorhabdin D 25:823 12-Hydroxy-E-T-bisabolene 23:166 20-Hydroxyecdysone 22:376;25:413 Hydroxyeicosatetraenoic acids 22:112 Hydroxyeicosatrienoic acids 26:759 10-Hydroxyellipticine 6:507 anticancer activity of 6:507 from Strychnos dinklagei 6:509 spectral data of 6:518 17-Hydroxyellipticine 6:513-515 from Strychnos dinklagei 6:515 spectral data of 6:515,519 18-Hydroxyellipticine 6:515,516,519 m-Hydroxy-E-nerolidol 25:162 endo-2-Hydroxyepicamphor 4:660 Hydroxy-epoxides (hepoxilins) 9:577 8ot-Hydroxyeremophilone 15:242 (22 S-24R)-22-Hydroxyergos-4-en-3-one 418 19'-Hydroxyervafolen 5:129 8(x-Hydroxyestafiafin 27:578 1,3,5-tris-(2-Hydroxyethyl) cyanuric acid 12:411,415 2-oxazolidinone from 12:411, 415 2-(l'-Hydroxyethyl) propenoates 4:479 nuceophilic conjugate addition to 4:479 24-(13-Hydroxyethyl)-and 24-(carboxymethyl) steroids 15:79-81 absolute configuration of 15:79-81 3-([3-Hydroxyethyl)-coronaridine 9:171 (S)- 1-(1 '-Hydroxyethyl)-[3-carboline 18:726 3S-3D-Hydroxyethylcoronaridine 5:126 5-Hydroxyethylmellein 9:288,289 (N-2-Hydroxyethylpiperazine-N'-2ethane-sulfonic acid) buffer 15:443 Hydroxyethylrutosides 22:437;26:756 6a-Hydroxyeurycomalactone 23:301
12-Hydroxyfarnesol 25:165,166 4-Hydroxyfarnesolacetate 27:586 5-Hydroxy-ferulic acid 5:469,470 Hydroxyferuloyl-CoA 5:470 7-Hydroxyflavanone 4:378,380 3-Hydroxyflavanones 7:192 3-Hydroxyflavone 22:327;26:757, 761-764,768,769 5-Hydroxyflavone 5:630;22:327;25:543 2'-Hydroxyflavone 5:12-14 2'-Hydroxyflavonoids 5:640 2'-Hydroxyflavonol-3-methyl ethers 5:640 Hydroxyframoside A&B 26:325,326, 333 2 lot-Hydroxyfriedela-3-one 5:744,746 7-Hydroxyfrullanolide 9:143-145 from Spharanthus indicus 9:143 2-Hydroxyfuran-2-one 30:222,224 as ascorbic acid analogue 30:224 decarboxylation of 30:222 lactonisation of 30:222 18-Hydroxygardnutine 15:502 10-Hydroxygeissoschizol 5:126 10-Hydroxygeissoschizol diacetate 9:174 14-Hydroxygelsedine 15:482 from Gelsemium elegans 15:482 from Gelsemium sempervirens 15:482 14[3-Hydroxygelsedine 9:196 14-Hydroxygelsemicine 15:481 from Gelsemium sempervirens 15:482 14-Hydroxygelsemicine 9:196,197; 15:481,482 from Gelsemium elegans 15:482 8-Hydroxygeraniol 25:140 11-Hydroxygeranylacetone 25:165,168 13-Hydroxygibberellins 6:181 preparation of 6:181 12-Hydroxygibberellins 6:190-194 preparation of 6:190-194 3-Hydroxyglabrol 28:228 biological activity of 28:228 (+)-7 ct-Hydroxyglaucines 16:504 (+)-7 [3-Hydroxyglaucines 16:504
405 (2R,3R)-3-Hydroxyglutamic acid 12:477 synthesis of 12:477 13-Hydroxyglutarate 11:127 naphthalenediol from 11:127 3-Hydroxyglycals 3:228 3a-Hydroxy-gomeric acid 25:249 3-Hydroxyguaiazulene 14:321,324 413-Hydroxyhernandulcin 15:15; 27:13,21 structure of 27:21 (+)-N-Hydroxyhernangerine 30:564,589 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:589 (R)-2-Hydroxyhexadecanoic acid 1:681 8-Hydroxyhexadecanoic acid 1:683,684 synthesis of 1:683,684 6-Hydroxyhexadecanoic acid 21:188 Hydroxyhexadecanoic acid (tricolorin A) 25:543 2 '-Hydroxyhexadecanoyl- 1-O-[3-Dgluc op yrano syl-9-methyl-4,8-Derytho-sphingadienine 18:814 10-Hydroxyheyneanine 5:127; 9:174-176 11-Hydroxyheyneanine 5:127 (+)-20-Hydroxyhobartine 11:323 (+)-aristocarbinol from 11:323 (+)-aristolasene from 11:323 aristolarine from 11:323 sorelline from 11:323 3[3-Hydroxyholosta-7,25-dien- 16-one 7:275,279 3 [3-Hydroxyholosta-9(11),25-dien- 16one 7:277,278 15-Hydroxyhumantenine 15:472,473 7[3-Hydroxyhyoscyamine 17:397-399 6[3-Hydroxyhyoscyamine 17:398-399 Hydroxyhyperforin 30:613 structure of 30:613 14-Hydroxyhypocretenolide 29:90 activity in NFkB assay system 29:90 activity in CRO assay system 29:90
14-Hydroxyhypocretenolide- [3-Dglucoside-4',4"-hydroxy-hypocretenoate 29:90 activity in CRO assay system 29:90 activity in iNOS assay system 29:90 activity in NFkB assay system 29:90 12-Hydroxyibogaine 21:72,84 19R-19-Hydroxyibogamine 5:126 19R-Hydroxyibogamine pseudoindoxyl 5:123 19R-Hydroxyibophyllidine 5:127 19-Hydroxyibophyllidine 9:190,192 5-Hydroxyindole acetic acid 22:670 1-Hydroxyindolizidine 12:278,279 diastereomers of 12:278,279 (-)-( 1R, 8aS)- 1-Hydroxyindolizidine 12:278,281 enantioselective synthesis of 12:281 from Astragalus oxyphysus 12:278 from Rhizoctonia leguminicola 12:278 (+)-cis-l-Hydroxyindolizidine 12:279, 280 synthesis of 12:279,280 (+)-( 1S,8aS)- 1-Hydroxyindolizidine 12:281 enantioselective synthesis of 12:281 from Rhizoctonia leguminicola 12:278 (+)-cis-2-Hydroxyindolizidine 12:284 (+)-trans-2-Hydroxyindolizidine 12:284 2-Hydroxyindolizidine 12:284 relative configuration of 12:284 synthesis of 12:283,284 6-Hydroxyindolizidine 12:285,286 synthesis of 12:285,286 7-Hydroxyindolizidine 12:285,286 antitremorine action of 12:286 synthesis of 12:286-289 cis-8-Hydroxyindolizidine 12:293 8a-Hydroxyindolizidine 12:300-303
406 1-Hydroxyindolizidine-6-carboxylic aid 12:283
17-Hydroxy-ingeno120-hexadecanoate
29:102 activity in mam-2 bioassay system 29:102 6ot-Hydroxyiridomyremcin 7:476 [3-Hydroxyisobutyric acid 13:87 (S)-[3-Hydroxyisobutyric acid 18:172 28-Hydroxyisoiguesterine 30:667 molecular formula of 30:667 Hydroxyisoindolone 13:114 3-Hydroxyisoleucine 15:347 Hydroxyisopiperitenone 25:151 Cis (3 S, 5R)-2-(2-Hydroxyisopropyl)-5methyltetrahydrofuran 25:143 16-Hydroxyisoretulinal 1:36;9:186 12-Hydroxyisoretulinal 1:36 18-Hydroxyisoretuline 1:38,39 c~-Hydroxy-isovaleric acid 13:533 3-R/S-Hydroxyisovoacangine 5:127 [3-Hydroxyketone 14:458,459;17:365; 30:23 1,3-anti reduction of 30:23 synthesis of 17:365;14:458,459 ot-Hydroxyketone 6:337;8:224,225; 14:458,459 synthesis of 6:337;8:224,225; 14:458,459 3-Hydroxykynurenine 26:965-967,988, 997,999 Hydroxyl inversion 1:204,205 13-Hydroxyl ofbaccatin III 12:218 Hydroxyl removal 1:454,456 3fl-Hydroxyl, A5'6 steroids 25:419 6-Hydroxy-l,2,3,4-tetrahydropyrrole (1,2-a) pyrimidinum skeleton 25:829 12S-Hydroxylabda- 8(17), 13(16), 14trien- 19-oic acid 29:101 activity in EBV bioassay system 29:101 ent- 15-Hydroxy-labda-8 (17), 13E-dien3-one 29:102 activity in EBV bioassay system 29:102 lc~-Hydroxylase 9:515 inhibitors of 9:515 25-Hydroxylase 9:520
Hydroxylated germacrene C2 23:160 Hydroxylated germacrene C5 23:160 Hydroxylated indolizidines 12:275-363 trans-Hydroxylation 1:413,414 of olefin 1:413,414 ofolefinic double bond 16:16 with H202 1:260 with WO3 1:260 cis-Hydroxylation 1:413,415;4:45,145, 204,205,344 lincosamine derivative from 4:145 of acrylates 4:45 of E-allylic alcohol 4:204 of Z-allylic alcohol 4:205 stereoselective 1:413,415,4:511 stereospecific 4:503,504 Whiteside's procedure 1:668 with Ba(CLO3)2 1:260 with CuC12/Cu/O2 5:827 with osmium tetroxide 4:508,509 with OSO4 1:260 with OsO4-chiral base 4:344 12~-Hydroxylation 13:663 t0-Hydroxylation 25:136,138,162,163, 166,168 c~-Hydroxylation 4:331,333;13:43; 27:199 of cyclic hydroxamic acid 27:199 Hydroxylation 5:827;24:70-72,76,178, 179;27:346,749,754;28:335 by cytochrome P450 27:346 by stereospecific double bond 11:464 of (1 'R)-(-)-Abscisic acid 27:348 of arenes 27:749 of indoles 27:754 of MFA 28:335 of paraherquamide A 28:331,367 o-Hydroxylation 5:826 of 2-alkylbenzoic acids 5:826 C-3Hydroxylation 7:359-361 1 l[3-Hydroxylation 9:417 Hydroxylation of tomatidine 25:318 15c~-Hydroxyleurosidine 14:812,813 from anhydrovinblastine N oxide 14:812,813
407 (15'R)-15-Hydroxyleurosidine 14:814, 815 (15'S)- 15'-hydroxyleurosidine from 14:814,815 Moffatt oxidation of 14:814,815 (2S,3R)-~-Hydroxy-L-glutamic acid 12:431,432 synthesis of 12:431,432 10-Hydroxyligstroside 26:334,343 8-Hydroxylinalool 25:136,140,142 8R-Hydroxylinoleic acid 21:187 9Z,12Z-8-Hydroxylinoleic acid 21:187 18-Hydroxylochnerine 13:386 23-Hydroxylongispinogenin 18:650,656 from Corchorus acutangulus 18:650 4-Hydroxy-L-proline 13:445 trans-4-Hydroxy-L-proline 13:485 (-)-6c~-Hydroxylupanine 15:524 (+)- 12ct-Hydroxylupanine 15:524 from Lygos raetam 15:524 313-Hydroxylupanine 21:80 6-Hydroxyluteolin 5:654,665 6-Hydroxyluteolin-6,7-disulphate 5:655 6-Hydroxyluteolin-7-O-(6"-caffeoyl)sophoroside 5:654 6-Hydroxyluteolin-7-sophoroside 5:624 6-Hydroxyluteolin-7-sulphate 5:655 18-endo-Hydroxymakomakine 11:326, 327 12-Hydroxymalagashanine 26:1053 (+)- 1313-Hydroxymamanine 15:523 from Maackia amurensis 15:523 13[3-Hydroxymamanine 27:267 X-ray analysis of 27:267 (-)-baptifoline 27:267 6-3a-Hydroxymanool 25:275 14o~-Hydroxymarcfortine A 28:338 synthesis of 28:338 15ct-Hydroxymarcfortine A 28:338 synthesis of 28:338 16(x-Hydroxymarcfortine A 28:338 synthesis of 28:338 5-Hydroxymatairesinol 18:601 5-allo-Hydroxymatairesinol 18:601 cis-( 3R,4R )-(-)-4-Hydroxyme llein 15:383 (R)-(-)-5-Hydroxymellein 15:383
3-Hydroxymellein 15:383 4-Hydroxymellein 15:383 trans and c&-(3S,4S)-4-Hydroxymellein 15:531 6-Hydroxymellein 25:498,499,506,507 Hydroxymellein synthase 25:483,506 6-Hydroxyme llein-O-methyltrans ferase 25:483 Hydroxymenthol 25:155 5-Hydroxymethlmellein 9:288,289 Hydroxymethyl C-glycoside 10:338 reaction with butyl lithium 10:338 from glycal 10:338 reactions with tributyltinmethyl iodide 10:338 3-Hydroxymethyl cyclopentanone 6:558 from 3-oxocyclopentane carboxylic acid 6:558 cis-2-Hydroxymethyl cyclopentylamine 22:294 trans-2-Hydroxymethyl cyclopentylamine 22:294 Hydroxymethyl indole 4:7153in Mannich reaction 4:715 cis-Hydroxymethyl oxocane 10:233 synthesis of 10:233 24-Hydroxymethyl steroids 15:79 absolute configuration of 15:79 (24S,22E)-24-Hydroxymethyl-(cholesta5,22-dien-3 [3-ol 15:98 (R)-l-(Hydroxymethyl) ethyl 2-glyceryl ether 6:387 from 2-amino-2-deoxy-3-O-(R)[hydroxymethyl) ethyl]-c~-Dglucopyranose 6:387 (S)-5-(Hydroxymethyl)-2-pyrrolidinone 11:264 from (S) pyroglutamic acid 11:264 Ent- 12[3-Hydroxymethyl-3-oxo- 16norpimar-8( 14)-ene- 15,21carbolactone 9:283,284 2R-Hydroxymethyl-3R,4S-dihydroxypyrrolidine 10:549 chemico-enzymatic synthesis 10:549
408
from Angylocalyx boutiqveanus 10:547 from Arachiodes standishii 10:547 synthesis of 10:548-549 yeast c~-glucosidase inhibitor of 10:547 2-Hydroxymethyl- 8-hydroxanthraqu inone-3-O-[3-D-glucoside 26:660 Hydroxymethylacylfulvene 22:260 2-Hydroxymethylanthraquinone 3glucoside 26:657 2-Hydroxymethylanythraquinone-3-O[3-D-glucoside 26:660 Hydroxymethylbilane (preurog'en) (HMB) 9:591,592,595 24(S)-Hydroxymethyl-chole sta-5,22(E)dien-3[3-ols 15:51 Hydroxymethylglutaryl coenzyme A reductase 13:553 4-Hydroxymethyl-iridoids 7:467,468 2-Hydroxymethylquinizarin 26:661 3-Hydroxymethylvoacangine 5:128 14c~-Hydroxy-MFA 28:340 biological activity of 28:340 Hydroxymycotrienin 23:54 Hydroxymycotrienin A 23:76 34-Hydroxymycotrienin II 23:76 12-Hydroxy-myricanone 26:895 4-Hydroxymyrtenal 23:819 5-Hydroxy-N,N-dimehtyl tryptamine 25:531 3'-R/S-H ydro x y-N 4-demethyl erv ahanine 5:125 3'-R/S-Hydroxy-Na-demethyltabernamine 5:124 Hydroxynagilactone F 28:4752anti-fungal activity of 28:475 1,4-Hydroxynaphthalene 23:53 Hydroxynaphthoquinone atovaquone 26:783 Hydroxynaphthoquinone metal complexes 30:314 as antitumor agent 30:314 8-Hydroxy-naringenin 28:64 antioxidant activity of 28:64 16-Hydroxy-Nb-demethylalstophylline oxindole 9:196,197
O-Hydroxynitropapuline 26:593 2'-Hydroxy-N-methylschumannificine 21:140 Hydroxynomuciferine 26:825 11-Hydroxynoracronycine 13:348,349, 356-358,366,367,370 fromAtalantia ceylanica 13:348, 349,356-358 synthesis of 13:356-358 18-Hydroxynorfluorocurarine 1:38,39 4-Hydroxyochratoxin A 15:388 Hydroxy-octadecandienoates 9:566 Hydroxyoctadecatrienoic acid 1:534536 synthesis of 1:534-536 Hydroxyomoside 26:318,321,322,325, 333,343 N-Hydroxyovigerine 30:564,589 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:599 3 [3-Hydroxy-oxo-7c~,11[3H-germacra4Z, 10(14)-diene- 12,6c~-olide 27:561 (4E, 8E)-N-D-2 '-Hydroxypalmitoyl- 1-O[3-D-gluc op yrano syl-9-methyl-4,8sphingadienine 18:813 O-Hydroxypap' ~ne 26:592,593 3-Hydroxyparatocharpin Cg 28:228 biological activity of 28:228 313-Hydroxyparthenolide 27:566 10-Hydroxypatchoulol 25:171,172 7-Hydroxypeganine 25:532 6[3-Hydroxy-pentahydroxy-agarofurano 18:746 6-Hydroxyperezone 5:766,794,795 ~3C-NMR spectrum of 5:766, 794,795 transformations of 5:794,795 15-Hydroxyperezone 5:795,796 transformations of 5:795,796 1-Hydroxyphenazine 26:365 Hydroxyphenolic acid 25:657 4(4-Hydroxyphenyl)-2-butanone 4'-0-[3D-(2,6-di-O-galloyl) glucopyranoside 29:588 as phenolic glycoside 29:588
409 4(4-Hydroxyphenyl)-2-butanone 4'-O-13D-( 2- O-galloyl-6-O-cinnamoyl)glucoside 29:569 as phenolic glycoside 29:589 p-Hydroxyphenyl- 1-bromoheptadecane 26:73 (x-Hydroxyphenylacetaldehyde 6:316,317 synthesis of 6:316,317 Hydroxyphenylethanol 15:351 4m-Hydroxyphenylpropionic acid (m-HHA) 25:922,923,947 4-Hydroxyphenylpyruvic acid 30:221 dimerisation of 30:221 15-c~-Hydroxypristimerin 30:665,692 ~3C heteronuclear correlation of 30:665 13C NMR of 30:665 ~H heteronuclear correlation of 30:665 IH NMR of 30:665 MS of 30:665 ROESY experiment of 30:666 (+)- 1-Hydroxypinoresinol 5:523,533, 537,538,542;26:200,270 (+)- 1-Hydroxypinoresinol dimethyl ether 5:533-534,536 (+)- 1-Hydroxypinoresinol- 1- 13-Dglucoside 5:523,538,542 (+)- 1-Hydroxypinoresinol-4'-O-methyl ether 5:523,533-536 (+)- 1-Hydroxypinoresinol-4'- f3-Dglucoside 5:523 (+)- 1-Hydroxypinoresinol-di- [3-Dglucoside 5:523 10-Hydroxy-p-methoxybenzoate 5:725, 726 15-c~-Hydroxypristimerin 30:665,692 against HeLa (human carcinoma of cervix) 30:692 cytotoxic activity of 30:692 Hydroxypristimerinene 5:747,749 17c~-Hydroxyprogesterone 9:415,416 from androstenedione 9:415 6a-Hydroxypterocarpans sphenostylins B 7:413,414
6a-Hydroxypterocarpans sphenostylins C 7:413,414 6-Hydroxypyrano [2,3-c] acridin-7-ones (noracronycines) 13:348 Hydroxypyrrol-2(5H)-one 13:117,11833-Hydroxypyrrole-2-carboxylates 8:272 8-Hydroxyquinaldic acid 26:991 microbial transformation of 26:991 8-Hydroxyquinaldic acid 26:991 8-Hydroxyquinoline 2:244;5:752;9:540 12-Hydroxyretulinal 1:36 3c~-Hydroxyreynosin 27:555 3-Hydroxyrifamycin S 23:61,81 30-Hydroxyrifamycin W 23:61 18-Hydroxysacculatal 2:278,279 19-Hydroxysacculatal 2:278,279 3-Hydroxysampangine 23:3,6 4-Hydroxysampangine 23:6 8etHydroxysantamarine 27:556 15-Hydroxysantonin 24:124,125 Hydroxysantonin 24:54,55 (+)- 13a-Hydroxysepticine 12:278 5-Hydroxysiastatin 16:86 from bovine liver 16:86 7~-Hydroxysitosterol 25:56 diacetate 25:56 2313-Hydroxysolanidine (leptinidine) 7:18,22 13a-Hydroxyspeticine 12:301 12(x-Hydroxyspongia- 13(16), 14-diene 1:662,663 synthesis of 1:682,683 (+)- 12(x-Hydroxyspongia- 13(16), 14diene 6:111,116 synthesis of 6:111,112,115,116 7-Hydroxystaurosperine 12:366,368 from Streptomyces sp. N- 126 12:366,368 11-Hydroxystaurosperine 12:366,370 from Eudistoma sp. 12:366,370 7c~-Hydroxystaurosporine 21:264 11-Hydroxystaurosporine 23:259 8-Hydroxystearic acid 21:188 24-Hydroxysteroids 15:76,77 absolute configuration of 15:76,77
410 26-Hydroxysteroids 15:77,78 absolute configuration of 15:77,78 313-Hydroxy-sterols 25:96,299,303 3-Hydroxystigmastan-6-one 9:288,289 N-Hydroxysuccinimidocarbonate 21:162 6a-Hydroxysugiol 29:99 activity in EBV assay system 29:99 (+)- 1-Hydroxysyringaresinol 5:524, 535-538 3-Hydroxytabernaelegantine 5:129 19R-Hydroxytabernaelegantine B 5:129 17-Hydroxytabersonine 4:57,58 19S-Hydroxytacamine 5:128;9:179 17-Hydroxytacamonine 5:126;9:180 7-Hydroxytectoquinone 26:661 2-Hydroxytetradecanoic acid 21:188 5-Hydroxytetrahydroharmane 5:125 Hydroxythymoquinone 5:763 3-Hydroxythymoquinone 5:767 6-Hydroxythymoquinone 5:767 20-Hydroxytingenone 30:668 IH NMR spectral data of 30:668 13C NMR spectral data of 30:668 NOE experiments of 30:668 stereochemistry of 30:668 20Gt-Hydroxy-tingenone 30:696 assay of 30:696 structure of 30:696 Hydroxy-tingenone 30:696 effect on feeding activity 30:696 effect on larvae development 30:696 effect on mortality 30:696 20-Hydroxytingenone 5:744,746,747 22-Hydroxytingenone 7:146 Hydroxytingenone 7:149 25-chloro-24-Hydroxytiruc all-7-en-3one 30:658 13C NMR of 30:658 HMBC spectrum of 30:658 molecular formula of 30:658 7-a-Hydroxy-tomatidine 25:318 16a-Hydroxytrametenolic acid 3-Oacetate lanostanes 25:63 I6a-Hydroxytrametenolic acid-3-Oacetate 25:61
3a-Hydroxytrichothecene 6:229,247 from 3-ketotrichothecene 6:229 6a-Hydroxytriptocalline A 30:641 structure of 30:641 3c~-Hydroxytropane 22:717 Hydroxytryptamine 30:37 structure of 30:370 Hydroxytropylium ion 1:568 5-Hydroxytryptamine 21:10;22:21; 30:370,384 [3H]-5-Hydroxytryptamine 25:31 5-Hydroxytryptamine 5:125;15:328; 25:529,531 5-Hydroxytryptophan 6:319;30:369, 370,371 structure of 30:369,370 5-Hydroxytryptophan 5-Hydroxytryptophan(5-HT) 30:384 3ot-Hydroxy-urs-12-ene 22:103 fl-Hydroxy-urs-12-ene 22:1033 11-Hydroxy-valenc- 1( 10)-en-2-one 23:635 Hydroxyvalidamine 10:518;13:189, 195,197 19-Hydroxyvandrikine 9:193 Hydroxyverniladin 26:808 Hydroxyvinamidine 2:389,390,398 14c~/14[~-Hydroxyvincadifformine 14:831 12-Hydroxyvincadifformine 5:124 15[~-Hydroxyvincadifformine 5:169-171 19-Hydroxyvincamajine 5:155,156 lc~-Hydroxy-vitamin D 10:45,49 1a-Hydroxyvitamin D analogues 30:485 structures of 30:485 1c~-Hydroxyvitamin D2 11:381-383, 385,395,402 l[3-Hydroxyvitamin D2 11:402-404 synthesis of 11:402-404 25-Hydroxyvitamin D2 9:512,513,515, 520,521;11:381 24-Hydroxyvitamin D2 9:513 1[~-Hydroxyvitamin D3 11:402-404 25-Hydroxyvitamin D3 12:401 1a-Hydroxy-vitamin D3 9:518,519
411 1a-Hydroxyvitamin D3 ((1 S)hydroxycalciol) 11:380,381,385, 395,402 25-Hydroxyvitamin D3 (calcidiol) 11:380,388-393 11-Hydroxyvittatine 26:610 3-Hydroxyvoacangine 5:124 6ot-Hydroxyvouacapan- 17,713-1actone 29:103 activity in AOS bioassay system 29:103 Hydroxywilfordic acid 23:674 4-Hydroxywithanolide E 20:223 14[3-Hydroxywithanone 20:180,242 Hydroxyxanthone 25:327,349,354,361 (-)-6'-Hydroxyyatein 26:192,212; 30:569,587 cytotoxicity of 26:212 dibenzylbutyrolactone-type lignan 30:587 ~H NMR spectrum of 30:587 lH-1H COSY of 30:587 HREIMS of 30:587 IR spectrum of 30:587 molecular formula of 30:587 NOESY of 30:587 UV absorption of 30:587 11-Hydroxyyohimbine 22:9 15-Hydroxy-Z-5,Z-8, Z- 11,E- 13eicosatetraenic acid methyl ester 2:12 2-Hydroxyzanthone 5:759 x-Hydroxy-c~,13- unsaturated aldehydes 7:459,460 8-Hydroxy-a-humulene 29:91 activity in EBV assay system 29:91 o~-Hydroxy-13-amino acid 12:493 synthesis of 12:493 [3-Hydroxy-[3-eudesmol 27:558 (R)-c~-Hydroxy-[3-phenyl propionate 12:479 (3R,4S) statine from 12:479 Hydrozirconation 10:59;13:486 Hydrozyindolizidine 12:293 8Hygrine 22:724 (+)-Hygroline 7:192
Hylauronidase 25:47 inhibition of 25:47 Hylobius abietis 27:385 Hylomecon genera 27:163 Hylophora cecropia 22:383 Hymenaceae sp. 25:252 Hymenaea ablongifolia 25:252 Hymenaea courbaril 22:66 Hymenaea parvifolia 25:252 Hymenamide F 25:830,863 Hymeniacidon aldus 21:270 Hymeniacidon sp. 21:349;25:713,797, 798,799,830 Hymenialdisine 21:270,271,285; 25:711,787,795 Hymenidin 21:270 Hymenin 21:68;29:91 activity in TPA assay system 29:91 Hymenolepis nana 26:484 Hymenomycetes 9:202,203 Hymenoptera 21:612;22:371 Hymenoxys turneri K. Parker 15:32; 27:17,18,35 (2R, 3R)-Dihydroquercetin 3-0acetate from 27:17 (2R, 3R)-2,3-Dihydro-5,7,3 '-4'tetrahydroxy-6-methoxy-3-Oacetylflavanol from 27:17 (2R, 3R)-2,3-Dihydro-5,7,3 ',4'tetrahydroxy-6-methoxyflavanol from 27:17 (2R, 3R)-2,3-Dihydro-5,7,4'trihydroxy-6-methoxy-3-Oacetylflavanol from 27:18 Hymeriacidon sp. 25:870 Hyodeoxycholic acid 16:352 Hyophyllanthin 26:233 Hyosciamus 22:422 Hyoscyamine 11:204,206;13:662; 17:398-400,417 from phenyl alanine 11:204,206 (S)-tropic acid moiety of 11:204,206 613-Hyoscyamine 13:662 L-Hyoscyamine 21:104 Hyoscyamine 21:56,98,109 (+)-Hyoscyamine 22:718,726,730,735, 741,742
412
Hyoscyamus albus L. 17:398;22:742 Hyoscyamus genus 17:395 Hyoscyamus muticus 22:742 Hyoscyamus niger 13:631;22:523,721, 732,734,742 for epilepsy 22:523 Hyoscyamus niger 22:523 for epilepsy 22:523 Hyoscyamus sp. 21:104,488 Hypaconite 24:898-899 neuromuscular blocking effect 24:898-899 Hypaconitine 24:898-900 in neuromuscular blocking effect 24:898,899 Hypecoideae 27:161 Hypecorine 6:494 Hypecoum genera 27:163 Hypecoum imberbe 27:167,168 Hypecoum leptocarpum 27:168 Hyperbrasilone 23:343 Hypercalcemic activity 30:497 of 24-epi-1 et,25(OH)2Dz 30:497 of lc~,25(OH)zD7 30:497 Hypercholesterolemia 21:212,669; 22:250,252 c-rt-Hyperconjugation 12:454 Hypercytokinemia 25:463 Hyperenone-A 5:759 Hyperenone-B 5:759 Hyperevolutin A 22:656 Hyperevolutin B 22:656 Hyperforat 22:691 Hyperforin 22:645,646,650,652,654, 658,669,678,696;25:537,538;30:611, 627,628 against Bacillus cereus 30:628 against Bacillus subtilis 30:628 against gram-positive bacteria 30:628 against Staphyllococcus aureus 30:628 alkylation of 30:627 by acylation 30:627 chemical structure of 30:611 cleavage of 30:611 effect on re-uptake of neurotransmitters 30:627
HPLC-ESI analysis of 30:611 MS n analysis of 30:611 oxidation of 30:627 Hyperforin derivatives 7:420,421 Hyperforin inhibitors 30:627 in depression 30:627 serotonin as 30:627 dopamine as 30:627 noradrenaline as 30:627 GABA as 30:627 Hyperici oleum 22:652 Hypericin 22:644,648,664,670,673,675, 678,683,684,685 ;26:375 ;27:850,851; 30:345,607,608,624,626-628 against herpes simplex virus types I and II 30:627 against retrovirus 30:627 against vesicular stomatitis 30:627 as antibiotic from 30:628 as inhibitor 30:626 as inhibitor of virus replication 30:628 as photoreceptor 30:607 as virucidal agents 30:627 in vivo virucidal efficacy 30:628 mechanism of action of 30:626 minimum inhibitory concentrations (MIC) 30:628 retroviral activity of 7:421 use for mild depression 30:345 use for moderate depression 30:345 virucidal effect of 30:627 Hypericoideae 30:604 Hypericum annulatum 7:417;30:611, 616,619,624 acetylannulatophenonoside from 30:624 annulatophenonoside from 30:624 glycosilated benzophenone from 30:624 phloroglucinol from 30:616 phytochemical studies of 30:611 terpenoid moieties from 30:616 Hypericum ascyron 30:620 in treatment of abscesses 30:620 in treatment of headache 30:620
413
in treatment of nausea 30:620 xanthones from 30:620 Hypericum barbatum 22:656;23:343; 30:607,611,629 against Bacillus subtilis 30:629 hydrocarbons from 30:607 prenylated phloroglucinols from 30:611 phloroglucinols from 30:629 terpenes from 30:607 Hypericum calycinum 7:422;26:797; 30:619 calycinoxanthon D from 30:619 phloroglucinol from 26:797 xanthones from 30:619 Hypericum chinense 7:422;22:656 Hypericum compound H8 (prenylated xanthone) 29:579,581 effects on ACE 29:579 effects on NEP 29:581 Hypericum drummondii 22:657;30:611 prenylated phloroglucinols from 30:611 Hypericum elegans 30:606 tlypericum erectum 24:273 Hypericum extracts 30:626 in vitro 30:626 inhibitor of dopamine 30:626 inhibitor ofnoradrenaline 30:626 inhibitor of monoamine neurotransmitters 30:626 inhibitor of serotonin 30:626 Hypericum geminiflorum 30:622 2,3-dihydroxy- 1,6,7-trimethoxyxanthone from 30:622 3,6-dihydroxy- 1,5,7-trimethoxyxanthone from 30:622 6,7-dihydroxy- 1,3-dimethoxyxanthone from 30:622 gemixanthone from 30:622 Hypericum genus 30:603 bioactivity of 30:603 secondary metabolites from 30:603 Hypericum hirsutum 22:675,647; 30:606,619 biflavone from 30:619 flavonoids from 30:619
Hypericum humifusum 30:606,619 flavonoids from 30:619
Hypericum hyssopifolium 22:672 Hypericum inodorum 30:619 xanthones from 30:619
Hypericumjaponicum 5:758;22:657; 30:611,614,629 antimicrobial activity of 30:629 as herbal drug 30:614 for gastrointestinal disorders 30:614 for hepatitis 30:614 in diseases 30:614 in treatment of bacterial infections 30:614 prenylated phloroglucinols from 30:611 Hypericum maculatum 22:647;30:619 flavonoids from 30:619 Hypericum montanum 30:606,619 biflavone from 30:619 flavonoids from 30:619 Hypericum mysorense 5:758,759; 30:629 against Bacillus coagulans 30:629 against Bacillus megatorium 30:629 against Bacillus subtilis 30:629 against gram-positive organisms 30:629 against Staphyloccus aureus 30:629 Hypericum nummularium 22:647 Hypericum olympicum 30:619 flavonoids from 30:619 Hypericum papuanum 30:616 in treatment of sores 30:616 papuaforins A-E from 30:616 prenylated phloroglucinols from 30:616 tricyclic acylphloroglucinols from 30:616 Hypericum patulum 30:619,622,629 against Eisenia coli 30:629 against Pseudomonas cepacia 30:629 flavonoids from 30:619
414
Hypericum perforatum 5:656,758; 21:541 ;22:643,653,661,664,666,672, 673,675,676,679-690;25:557;29:580; 30:407,603,604,605,609,610,616, 618,619,622,624,626-629 against infected wounds 30:628 against skin lesions 30:628 antimicrobial activity of 30:628 antiviral activity of 30:407,627 biflavone from 30:619 cell cultures of 30:609 chemotaxonomic study of 30:619 constituents of 30:605 extract of 30:624 flavonoids from 30:616,618 HPLC of 30:624,626 hyperoside from 30:618 m depression treatment 30:624, 629 in treatment of abdominal pain 30:603 in treatment of isoquercitrin from 30:618 in treatment of melancholia 30:603 m treatment of ulcerated burns 30:603 in treatment of urogenital pain 30:603 lsovaleric acid from 30:605 mechanism of action of 30:624 parts of 30:609 paxanthone from 30:622 pharmacology of 30:624 phenotypic characters of 30:604 phloroglucinols from 30:610 c~-pinene from 30:605 quercetin from 30:618 quercetin-arabinoside from 30:616 quercetin-galacturonide from 30:616 quercitrin from 30:618 rutin content of 30:616 rutin from 30:618 subspecies of 30:604 var. angustifolium 30:604 var. microphyllum 30:604
var. perforatum 30:604 varieties of 30:604 veronense from 30:604 volatile oil from 30:605 xanthones from 30:619 Hypericum pulchrum 30:606 Hypericum revolutum 7:409,410,417, 420-422;22:655 ;23:342 Hypericum roeperanum 29:581 ;30:619, 620 (5-O-demethyl paxanthonin) from 30:620 calycinoxanthon D from 30:619 roeperanone from 30:619 xanthones from 30:619 Hypericum sampsonii 30:622 against diarrhoea 30:622 against snake bites 30:622 against swellings 30:622 Hypericum sarothra 30:605 n-nonane from 30:605 Hypericum scabrum 30:616 hyperibones A-I from 30:616 Hypericum sp. 27:850 Hypericum tatrapterum 30:606,619 flavonoids from 30:619 Hypericum triquetrifolium 22:647,673 Hypericum uliginosum 22:657 Hyperin 7:227 Hyperkinetic ventricular arrhythmias 25:594 Hyperlipemia 22:607,608 Hyperlipidaemia 27:405;30:55,56,58, 70,83,88,98,101 biological activity of 27:405 due to high-fat diet 30:98 in mice 30:101 prevention of 30:56 role of natural products in 30:55 treatment of 30:56 use of Ganoderman lucidum in 30:58 use of Laminaria japonica Aresch in 30:56 use of orlistat (Ro 18-0647) in 30:83 use of Platycodi radix 30:88 Hyperosid 22:645;26:666
415 Hyperplasia 30:375 of cerebral grey matter 30:375 of cerebellae white matter 30:375 Hyperpolarisation 21:101 Hypersensitive response 25:394,402; 27:61 Hyperserotonemia 30:381,368 in autism 30:381 Hyperstable olefins 12:207 Hypertension 30:55,58,72,201,368 role of Angelica keiskei in 30:72 role of Ganoderman lucidum in 30:58 role of natural products in 30:55 role of serotonin (5-HT) in 30:368 Hypertrehalosaemic hormones 9:487 Hyphochytridimycetes 9:202 Hyphomonasjannaschiana 25:873 Hyphomycetes 9:203 Hypnophilin 3:7,65;22:195,202,208 Hypocholesterdemic effects 25:222 ofsoyabean saponins 25:222,223 Hypocholesterolemic agent 13:554; 21:616;26:246 Hypocholesterolemic atherosclerosis 26:248,249 Hypocholesterolemic drug 5:195 Hypocholesterolemic effect 26:44,54, 205 of Gypsophila capitala 26:44 Hypocholesterolic effects 26:233 Hypocholorous acid 25:931 Hypocrea muroiana 21:225 hypomurocins A,B from 21:225 Hypocrea sp. 21:203,224 Hypodiol 30:646 IH-IH COSY of 30:647 HMQC of 30:647 HOHAHA spectra of 30:647 NMR spectroscopic data of 30:646 NOESY spectrum of 30:647 stereochemistry of 30:647 structure of 30:647 Hypoglottis 27:61 Hypoglycemic effect 30:80,94,294 of Ajuga iva (L.) 30:294
of saponon 30:94 of tea saponin 30:80 Hypoglycemic activity 18:672;21:460, 488,666;26:398 Hypoglycemic agent 21:459,488 phytochemicals as 21:457 Hypoglycemic effects 17:139 Hypoglycin A 26:476 Hypolactin-6-glucoside 25:613 Hypolactin-8-glucoside 25:612,616 Hypolaetin 5:665;22:434,440 Hypolaetin-3'-methyl ether-7-glycosides 5:658 Hypolaetin-8-glucoside 22:434,440 Hypolepis puncatata 26:122 Hypolipaemic drug 5:695 Hypolipidaemic effects 27:400 Hypolipidemic action 26:887 Hypolipidemic activity 23:357;26:247 of scoparone 23:357 Hypoloside A&B 26:722 Hypooxidaceae 25:180 Hypoponera opacior 5:224,230,254 Hypopyhyllanthin 17:344 synthesis of 17:344 Hyporeales 9:203 Hypotensive action 28:200,209,207; 30:787 of isoprenylated flavonoids 28:207 ofkuwanon G 28:209 ofkuwanon H 28:200,209 mechanism of 30:787 ofMorus alba 28:200 of Morus species 28:207 ofmulberrofuran C 28:209 of mulberrofuran F 28:209 of mulberrofuran G 28:209 Hypotensive activities 17:451 ;21:690; 27:481 of Astragalus membranaceus roots 27:481,483 of cryptolepine 5:752 Hypotensive alkaloid 5:751,752 Hypothalamic neuropeptide 27:794 Hypothalamus 22:25 Hypothalamus-pituitary 27:794
416
Hypothermal activity 23:353 of Coumarin 23:335,353,356, 357,368,376,393,550,553 Hypothermia 30:194 due to opioids 30:194 Hypothermic activity 23:800 Hypothetical incorporation 11:195 of methylmalonyl CoA 11:195 with macrolide antibiotic 11:195 with polyether antibiotic 11:195 Hypothyroidism 30:374 autistic features in 30:374 Hypotriglyceridemic effect 26:246,261 Hypoxanthine 15:460;22:314 [G-H]Hypoxanthine 25:348 Hypoxanthine-guanine-phosphoribosyltransferase 15:371 Hypoxanthine-H 23:199 9-D-Hypoxanthines 4:224,225 Hypoxylon oceanicum 25:717 Hypselodoris californensis 6:20 curyfuran from 6:20 Hypselodoris godefroyana 6:69 curyfuran from 6:20 nakafuran-9 from 6:29 Hypselodoris nana 25:815 Hypselodoris porterae 6:20 Hypselodoris webbi 21:361 Hypselodory nana 26:463 Hypsochromic shift 30:539 Hyptis verticillata 21:599;26:212; 28:402 dehydro-[3-peltatin methyl ether from 26:212 5-methoxypodophyllotoxin from 26:212 Hyriopsis schlegelii 26:1123 Hyrtiomanzamine 25:710,819;28:691 immunosuppressive activity of 28:691 Hyrtios altum 25:727 Hyrtios erecta 25:696,698,710,819; 28:691 Hyrtios eubamma 6:23 puupehenone from 6:23 Hyrtios sp. 25:716 Hyrtios spicigora 25:276 Hysistozoa fasmeriana 28:635 Hysselodoris californiensis 4:404
Hysselodoris porterae 4:404 Hyssopus 26:746;29:579 Hyssopus officinalis 7:119 Hysteria 22:510,512,513,516,518,519, 521,522,525-529,531,534
A chyranthes aspera L. for 22:510
Acorus calamus L. in 22:510 Anagallis arvensis L. for 22:512 Asarum maranthuym Hook. for 22:513
Cinnamomum camphora for 22:516
Cynodon dactylon L. for 22:516, 518
Dictamnus albus L. 22:519,521 Ferula alliacea for 22:521 Flemingia strobilifera for 22:521 Galium verum L. for 22:521 Hibiscus abelmoschus L. for 22:522
Linum usitatissimum L. for 22:525
Lobelia inflata L. for 22:525 Martynia chamomilla L. for 22:526
Matricaria aurea L. for 22:526 Melissa offlcinalis L. for 22:526 Moringa oleifera for 22:526 Musa paradisiaca L. for 22:526 Nordostachysjatamansi DC. For 22.'527 Olacaceae for 22:720 Paeonia emodi for 22:528 Paeonia officinalis L. for 22:528,529 Peganum harmala L. for 22:529 Ruta graveolens L. for 22:531 Sapindus trifoliatus L. for 22:531 Valeriana hardwickii for 22:534 Valeriana officinalis L. for 22:534 Valeriana wallichii for 22:534 Hysterin 29:90 activity in TPA assay system 29:90 Hystero-epilepsy 22:513,525,527,528, 531,532,534
417
Benincasa hispida use for 22:513 Mangifera odorata L. for 22:525 Nardostachysjatamansi DC. For 22:527 Paeonia emodi for 22:528 Sapindus trifoliatus L. for 22:531 Semecarpus anacardium L. for 22:532 Valeriana hardwickii for 22:534 Valeriana officinalis L. for 22:534 Valeriana wallichii for 22:534 Hystiomanzamin 25:819 Hytakerol 9:513 Hytis spicigora 25:276 IAA oxidase 25:657 Ianchinenoside E 26:38 c-AMP phosphodiesterase inhibitory activity of 26:38 Ianthella basta 25:719;28:695,714 as Ca2+-channel agonists 28:695 Ianthella flabelliformis 28:714 Ianthella sp. 28:695 Iantheran A 28:695 as Na+/K+-ATPase inhibitor 28:695 Iberis amara 19:762,20:12 Iberis umbellata 29:53 Ibhaynid 25:802 Ibisterol sulfate 28:700 against HIV-1 28:700 Iboga alkaloids 1:112,93-96,163165,422 Ibogaine 5:101,126,174;21:70,72,95; 22:18,24,435,542;25:533,537 as immunosuppressive drug 25:533,537 Ibogaine hydroxyindolenine 5:101,126 Ibogaine pseudoindoxyl 5:126 Ibogaline 5:127,174 dl-Ibogamine 14:806,807 Ibogamine 25:533,537 as immunosuppressive drug 25:533,537 (-)-Ibogamine 5:124
(+)-Ibogamine 5:125 Ibogamine pseudoindoxyl 5:126 Ibogan 26:139 Ibogan-type alkaloids 5:71 Ibophyllidine 5:126,847;9:190,192 synthesis of 14:847 2--epi-Ibophyllidine 5:126 Ibophyllidine-Na-oxide 5:126 Ibophyllidine-type alkaloids 5:100 desethylibophyllidine 5:100 19-hydroxyibophyllidine 5:106 18-hydroxy-20-epiibophyllidine 5:106 19R- 19-hydroxy-20-epiibophyllidine 5:106 19S-19-hydroxy-20-epiibophyllidine 5:106 ibophyllidine 5:106 20-epi-ibophyllidine 5:106 19S-iboxygaine 5:106 Ibotenate 25:531 19-epi-Iboxygaine 5:126 Iboxygaine hydroxyindolenine 5:127 19-epi-Iboxygaline 5:127 Iboxyphylline 14:847 synthesis of 14:847 Ibuprofen 30:192 as cyclooxygenase enzyme (COX) inhibitor 30:192 Ibuprophen 6:322,323 ICAM-1 expression 30:70,71 inhibitory effect on 30:70,71 Ichikawa 29:492 carbaoxirose/carbaoxetoses synthesis by 29:492 Ichorati 17:200 Ichthyotoxic 21:267,275,365 Ichthyotoxic activity 28:698 ofhalistanol sulfate 28:698 Ichthyotoxic agent 21:267,275,365 Ichthyotoxic malyngomides 25:757 Ichthyotoxicity 17:24;18:607,716 Ichthytoxic activity 25:768;26:485 Ichtyotoxic agent 25:730 Icosanoid 25:945 all, cis-5,8,11,14,17-Icosapentaenoic acid 21:306 Icosapolyenoic acids 9:559 Icosatetraenoates 9:566
418 (5,8,11,14Z)-Icosatetraenoic acid 9:560 Icosatetraynoic acid 9:564 8,11,14-Icosatrienoic acid 9:577 Icsatrienoic acid (dihomo-T-linolenic acid) 9:564 Ictalurus punctatus 26:353 IDDM 21:458 Idicol 26:850 L-Idopyranose analogs 6:369,370,372, 373 Iedania ignis 28:692 Iejimalides (A-D) 10:247,19:606 IFN- T 21:651,666;25:465 IFN-c~ 21:651,656 IG isotypes 24:168-170 IgE production 30:773 inhibition of 30:773 against casein 30:773 IgE/anti Ig E complexes IgGl-antibodies 21:646 IgG2a-antibodies 21:646 Iguesterin 5:747,18:757,776 (+)-Ikarugamycin 21:411 Ikarugamycin 4:620;10:153,18:10-17; 23:51 ;28:138,140 anti-bacterial activity of 28:140 antiprotozoal activity of 28:138 biosynthesis of 4:620 Ikegami 29:485 valiolamine synthesis by 29:485 IL (Interleukin) 25:455 IL- 1ct 30:689,771 inhibitory activity of 30:689 IL-113 30:689 inhibitory activity of 30:689 IL-2 production 30:782 by macrophages/dendritic cells 30:782 by TLR2 signaling 30:782 Ileostylus micranthus 28:454,464 Ilex aquifolium L. 20:6;22:523 for epilepsy 22:523 Ilex crenata 21:657 ilexosides A,B,C and D from 21:657 18,19-seco-ursane glycosides from 21:657 Ilex lactone 20:6
Ilex paraguariensis 20:6;21:671;27:299 Ilex verticillata 9:402 Ilicic acid 29:87 activity in TPA, AA, EPP assay systems 29:87 Ilicicolin H 4:620 biogenesis of 4:620 Ilicifoline 23:695 Ilimaquinone 5:430;15:291,314 absolute configuration of 5:430 antimicrobial activity of 5:434, 437 5-epi-Ilimaquinone 9:31;15:315,319 oxidative degradation of 9:31 Illicic acid (vachanic acid) 7:212 Illicium verum Hook f. 21:596;27:16 trans-anethole from 27:16 Illudanes 26:705 Illudin M 22:260;26:706 Illudin S 22:260 Ilybius fenestratus 5:780 Imanine 30:628 antibacterial properties of 30:628 Imberic acid derivatives 25:183 Imbricatine 7:306,307 Imbricatosides A 15:64 Imelutine 1:167 Imidazole 12:152;25:335 Imidazole [4,5-e-]-l,2-thiazine 25:897 Imidazolidines 1:349-351 2-azaallyl anions from 1:349-351 Imidazolidinone 8:156 Imidazolo [4,3-a] isoquinoline 12:447 Imidazolone 5:412 cytotoxic activity of 5:413,415 Imide enolates 12:164-168 4-acetoxy-13-1actam with 12:164-168 C4-alkylation with 12:164-168 from propionic acid derivatives 12:164-168 Imidoyl chloride 14:157 Imidoyl phosphate 8:79 synthesis of 8:79 Imine 12:173 [2+2] cycloaddition of 12:173 azaallyl anions from 1:331-344 cis reduction of 6:428
419
deprotonation of 1:331-344 preparation by Standinger reaction 1:352-353 trans reduction of 6:428 trans-3-acetyl-[3-1actam from 12:173 with diketene 12:173 ylides from 1:331-334 9-N- [2- Sulfoethyl)Imine 25:870 Iminium 'A' 2:390,2:398,402 Iminium 'B' 2:390,390 Iminium cyclization 1:243 Iminium ion cyclization 1:286,287 to vinylsilanes 1:286,287 Iminium ion-vinylsilane 19:52 Iminium ion-vinylsilane cyclization 12:454 ~-Imino carboxylic acid 8:384 2-Imino cyclic ethers 10:215 synthesis of 10:215 Imino Diels-Alder approach 14:732,733 Imino Diels-Alder reaction 4:36,37,604 13-Imino sulfoxide substrate 18:382 5,8- Imino- 7- O-me syl- 2,3,5,8-tetradeoxy-D-glucooctano- 1,4-1actone 12:325 Iminodienophile 4:604 in Diels-Alder reaction 4:604 Iminogalactitol 7:42 Imipenem 4:432;12:145 antibiotic potency of 4:432 N-formimidoly derivative of theienamycin 12:145 PBP-2 affinity for 4:433 Imipramine 22:672 Immobilised cultures 7:92 Immobilized glucoamylase 2:356 Immune disorders 30:484 use of l cx,25(OH)2D3 30:484 Immune response 30:766,770 against Listeria monocytogenes 30:770 by cx~ T cells 30:766 Immune-active acidic glycoprotein 25:455 from Chlorellavulgaris 25:455 Immune-mediated cytotoxicity 21:656; 25:467
Immune-suppression mycosis 22:56 Immunization 30:408 against measles 30:408 Immunoadjuvants 21:646 saponins as 21:646 Immunoadjuvant monophosphoryl lipid A in 18:918 Immunoadjuvant properties 6:385 Immunoadjuvant saponins 21:646 Immunoaffinity chromatography 25:382 Immunoassay screen 19:188 Immunoblotting 25:499 Immunocompetent organ toxicity 28:561 chitosan inhibitory effect on 28:561 Immunocompetent organic toxicity 27:436;28:560 of5-fluorouracil (5-FU) 28:560 Immunodeficiency syndrome 30:226, 394 causative agent of 30:394 Immuno-deficiency virus 22:646,648; 25:734;30:397 use of HIV-1 30:397 use of HIV-2 30:397 Immunodulatory activity 30:395 ofpolysaccharide (PS) 30:395 Immunofluorescence detection 26:935 of the putative NOS 26:935 Immunofluorescence microscopy 26:932 Immunogens 18:909-920 Immunoglobulin G 22:374;30:837 F-II hydrolysis of 30:837 Immunoglobulins 24:140-144 Immunohistochemical staining 25:442 Immunohistopathology 26:792 Immunological activity 23:107 of fungal [3-glucans 23:107 Immunological assays 15:361 Immunological role 30:422 of 3-deoxyulosonic acids 30:422 stereocontrolled chemical syntheses in 30:422 Immunomodulating action 24:131, 149-152 Immunomodulator activity 21:316,645; 23:129,687
420
of fungal B-glucans 23:129 Immunomodulation 7:16 by swainsonne 7:16 Immunomodulatory actions 26:1036 Immunomodulatory effect 21:134; 26:31,50,55 of Acanthophyllum squarrosum 26:55 of Gypsophila saponins 26:55 of squarroside A 26:31 ofVaccaria segetalis 26:50 Immunopathological reactions 26:787 Immunopharmacology 30:766 of Chlorella 30:766 of green algae 766 Immunopotentiating effects 25:429 of Chlorella vulgaris strain CK 22 (CVs) 25:429 Immunoprecipitated CDK2 kinase 21:136 Immunoreactive polypeptide 25:383 Immunosorbent assay 15:361 Immunostimulant effect 27:513 ofpolysaccharide 27:513 of Astragalus membranaceus 27:513 Immunostimulant saponins 21:646,651 Immunostimulating action 24:131, 144-148,153,171 Immunostimulating complexes 21:648 Immunostimulating saponins 24:131-171 Immunosuppressant agents 16:561 Immunosuppressants 22:248 Immunosuppressive activity 18:739, 921 ;23:522,649,681 ;26:214,482 of didenmins 10:257,258 of diterpene triepoxides 23:649 of euonine 23:681 of sesquiterpene pyridine alkaloids 23:649 of verbascoside 23:522 of wilfortine 23:681 of [3-apopicoropodophyllin 26:214 Immunosuppressive agent 22:527;30:3 discodermolide as 30:3 pironetin as 30:3 Immunosuppressive disease 30:396
Immunosuppressive drugs 21:661 ; 25:464 FK 508 as 25:464 dexamethasone as 25:464 amphetamine as 25:537 calebassine as 25:528 carcurine as 25:528 coronaridine as 25:533 eseramine as 25:536 eseridine as 25:536 harmaline as 25:537 harmine as 25:537 ibogaine as 25:533,537 ibogamine as 25:533,537 physostigmine as 25:536 physovenine as 25:536 reserpine as 25:538 sapargine as 25:528 strychnine as 25:530 tabemanthine as 25:533 toxiferine as 25:528 yohimbine as 25:530 Immunosuppressive effect 26:486;30:26 on blastogenesis 30:27 of pironetin 30:26 Immunosuppressive therapy 20:528 Immunotherapy 28:543 detox for 28:543 Immunotoxicity 28:562;30:56 by doxorubicin 28:562 due to cancer drug chemotherapy 30:56 Immunstimulatory activity 26:797 Impatiens repens 22:523 for epilepsy 22:523 Imperata cylindrica 26:233 graminone B from 26:233 Imperialine 21:56;22:19 in regulation of methyl CpG binding protein 30:373 In vitro 28:470,467;30:59,61,396,594, 596,810,815,816 antiplasmodial activity 30:596 antiplasmodial activity of chloroquine 30:596 antiplatelet aggregation turbidimetry assay 30:594 DNA synthesis 30:61 glycopeptides 30:815
421
HIV replication 30:396 Lewis lung carcinoma 30:59 of glycopeptides 30:816 of milanjilactone A 28:470 ofmilanjilactone B 28:470 ofnagilactone F 28:470 ofnagilactone G 28:470 ofpodolactones 28:467 receptor binding assay 30:810 In vitro bioassay 30:591 for chemopreventive activity 30:591 In vitro studies 30:61,195,203,593,597, 805,815 of anandamide 30:195 ofangiogenesis 30:61 of antinociception 30:805 of chloroquine potentiating antiplasmodial activity 30:597 of ginseng extract 30:203 of ginsenosides 30:203 of glyco analogues activity 30:817 ofherveline A 30:597 of mouse fail-flick assay 30:815 of parasitemia inhibitor 30:597 of tetrahydrocannabinol (THC) 30:195 of tumor-promotion 30:593 In vivo testing 24:491 of anti-viral agent 24:491 Inactivation pathway 27:321,345 of ABA 27:345 INADEQUATE 21:692 2D INADEQUATE spectrum 2:96,98 of dammmaran-20 (S) of 2:96,98 of salculaplagin triacetate 2:88 INADEQUATE spectrum 24:237,280 of euglobal-G2 24:237 Incartine 20:351 from Lycoris incarnata 20:351 Incarvillateine 30:204 as antinociceptive agent 30:205 from Incarvillea sinensis 30:204 inflammatory pain inhibition by 30:205 neurogenic pain inhibition by 205 Incarvillea sinensis 30:204 incarvillateine from 30:204
Indanoaziridine 1:189 from isoquinolinium betaine 1:109 Indanomycin 10:348 synthesis of 3:275,276 Indanone 11:115 Indaquassin-C 23:299 Indazole dione 2:215,217 Indenobenzazepine 1:218,219 biogenesis of 1:218,219 from 8,14-cycloberbines 1:209-211 from spirobenzylisoquinolines 1:207-208 oxidation of 1:216 reaction with Lewis acids 1:196,197 rearrangement to spirobenzylisoquinoline 1:205,206 synthesis of 1:196,197,205,206 trans-to-cis-isomerization 1:210 anti-Indenofluorenone 11:124 from 1,2,4,5-benzenetetra carboxylate 11:124 ~H-NMR of 11:124 syn-Indenofluorenone 11:124 from 1,2,4,5-benzenetetra carboxylate 11:124 lH-NMR of 11:124 Indicarol acetate 9:79,81,87 Indicine 1:269,270,325,326 synthesis of 1:270,325,326 Indicol 9:79,80,87 Indicoside A 15:61 fromAstropecten indicus 15:61 ~3C-NMR spectrum of 5:214 FAB mass spectrum of 5:214 ~H-NMR spectrum of 5:214 Indicoside B 5:215 Indicoside C 5:215 Indicosides A-C 7:299,301,302 from Astropecten indicus 7:299 Indicuminone 27:593 Indigo 1:20 reduction with hydrazine 1:20 Indigofera endecaphylla 19:117;27:522 Indigofera genera 27:519 Indigofera swaziensis 7:417
422
Indigofera tinctoria L. 22:523 for epilepsy 22:523 Indinavir 24:489 inhibitor of HIV- 1 protease 24:489 Indirect immunofluorescence 24:217 INDO MO method 18:981,985 Indobine 9:178 Indolalkylamines 9:510 Indole [2,3-a] carbazole alkaloid 5:55 Indole acetic acid 7:90,114 Indole alkaloids 1:31-34;2:172,173;5:3, 69-134,389,390,443,444 ;9:85, 163-199;13:70,92,93;10:407,411; 14:703-730 aspidosperma 13:70,92,93 Aspidosperma type 10:407,411 bisynthesis of 1:31-34 carbon 13 NMR of 9:165 CD of 2:172,173 Cotton effects in 2:172,173 hunteria 13:70,93 Hunteria type 10:407;13:70,93 identification of 9:163-199 mass spectroscopy of 9:165 synthesis of 14:703-730 thin layer chromatography of 9:164 UV spectroscopy of 9:164,173 Indole alkaloids 27:862;21:57,68,72,73, 84,107 Indole hallucinogens 25:531 psilocin 25:531 Indole N-tert-butyloxycarbonyl 3:309, 310 thermolytic deprotection 3:309, 310 Indole-2,3-quinodimethane 1:16,17 Indole-3-acetic acid 27:747 Indole-3-carboxaldehyde 21:240 Indole-3-pyruvic acid 12:374,375 biotransformation of 12:374 3-Indolecarbaldehyde 22:485 Indole-monoterpene alkaloids from Strychons dinklagei 6:503-522 from Strychnos species 6:503 of corynane strychnane series 6:503-520
Indoles 27:754 hydroxylation of 27:749,754 Indole synthesis 1:79,144,152 Fischer 1:79,144,152 Smith 1:360,365 Indoline derivatives 9:183-191 Indolizidine 9:72;21:56 2,3-Indolinone 22:79 (-)-(R)-Indolizidine 11:246-267;12:280 (+)-(S)-Indolizidine 12:280 (-)-Indolizidine 209D 16:489 synthesis of 16:489 Indolizidine 223A 27:242,243,287 GG-MS fragments of 27:242 Indolizidine 249H 27:243 structure of 27:244 Indolizidine 251M 27:242,243 mass spectrum of 27:243 Indolizidine 267J 27:242,243 5E,9E stereochemistry of 27:243 Indolizidine alkaloids 7:11-13,453-502; 25:190;27:233,235,236-238 1,4-disubstituted quinolizidines 27:238 3,5-disubstituted indolizidines 27:235,236 5,8-disubstituted indolizidines 27:235,238 from amphibians 27:234 from ants 27:234 pumiliotoxin alkaloids 27:238, 239 quinolizidine alkaloid 27:235, 236-238 spectral features of 27:236 structure identification of 27:240-247 structure identification of 27:247-249 structure of 27:233 synthesis of 1:360-365;10:556, 561;16:453-502 (+)/(-)Indolizidine alkaloids 11:246 absolute stereochemistry of 11:246 spectral data of 11:246,249,254, 255,11:264 synthesis of 11:246-267 asymmetric synthesis of 6:442,
423
443 in Solenopsis conjurata 6:450 synthesis of 6:442,443,445-451 (-)-( 1S, 2R, 8aS)-Indolizidine- 1,2-diol 12:303 configuration of 12:303 from Rhizoctonia leguminicola 12:303 (-)-swainsonine from 12:303 synthesis of 12:303-305 (1S,2R,8aR)-Indolizidine-1,2-diol 12:303,304 synthesis of 12:303,304 Indolizidine-7-one 19:33 Indolizidinediol 13:488 Indolizidines 19:25,32,38,45-46,48-51 synthesis of 19:42,32 enantioselective synthesis of 19:50 (-)-Indolizidines 205 A 16:479 synthesis of 16:479 (-)-Indolizidines 235B 16:479 synthesis of 16:479 Indolizidone 12:298 cross-aldolisation of 12:298 from L-proline thioester 12:297 (-)-Indolizomycin 12:301 absolute configuration of 12:301 antibiotic activity of 12:301 from Streptomyces grisline 12:300 from Streptomyces teryimanensis 12:300 reduction of 12:301 synthesis of 12:301-303 (+)-Indolizomycin 12:301-303 ;16:461 synthesis of 16:461 Indolo [2,3-a] carbazole alkaloids 12:365-409 biological activity of 12:384-399 synthesis of 12:375-383 Indolo [2,3-a] carbazoles 12:366,370 against Herpes simplex type 12:366,370 cytotoxic against human cancer ceU lines 12:370 from Nostoc sphaericum 12:366,370
Indolo [2,3-a] pyrido [a] quinolizine 3:404 1H-Indolo [2,3-a] pyrrolo [3,4-c] carbazole 12:365 Indolo [2,3-a] quinolizine 1:142,144, 153,155 synthesis of 1:142,144,153,155 Indolo [2,3-a] quinolizine alkaloids 8:288 synthesis of 1:123,159 Indolo-[2,3-a] quinolizidine 14:722-724 by alkaline decarboxylative cyclization 14:722-724 by Claisen rearrangement 14:722-724 preparation of 14:704-706, 720-724 Indoloazacyclodecane 14:862 Indoloazepine 14:831,832 14c~ and 14[3-hydroxyvincadifformine from 14:831,832 condensation of 14:831 epi-pandoline from 14:831 pandoline from 14:831,832 with 4-ethyl-4,5-epoxy pentanal 14:831 Indolocarbazole 21:263 Indolocarbazole alkaloids 1:6 biosynthesis of 1:6 Indoloquinolizidine 1:115,116;1:99, 100,712;15:497;25:4,28 Indoloquinolizidine aldehydes 1:111 Indoloquinolizidine enamines 14:727 preparation of 14:727 Indoloquinolizidine iminium salts 14:715-718 by Polonovski reaction 14:715-718 from indolo [2,3-ot] quinolizidine N b oxides 14:715-718 Indoloquinolizidine Nb-metho salts 14:718,719 preparation of 14:718,719 stereoselective 14:718,719 Indoloquinolizidine Nb-oxides 14:712 conformational equilibrium of 14:712 preparation of 14:711-714
424
stereoselective synthesis 14:711-714 3-Indolyl acetic acid 9:236 bis-Indolyl maleic anhydride 12:381 bis-Indolyl maleimides 12:365,372, 375-383 biological activity of 12:384-399 protein kinase activity of 12:389 1-[ 2-(3- Indo lyl) ethyl]- 3-methoxy carbonyl 1,4,5,6-tetrahydro pyridines 14:720 alkaline decarboalkoxylative cyclization of 14:720 indolo [2,3-a] quinolizidines from 14:720 2-(2-Indolyl)-propionic acid 9:236,237 3-Indolylacetaldehyde 11:288 2-Indolylacetaldehyde 11:315,316 from N-(p-MPS) indole 11:315, 316 preparation of 11:315,316 3-Indolyl-acetonitrile 11:281,282 Ritter reaction of 11:281,282 with (-)-13-pinene 11:281,282 Indolylmagnesium iodide 1:7 Indomethacin 7:397;20:514;25:56,58, 593,595,613,616;27:689,690;30:192 as cyclooxygenase enzyme (COX) inhibitor 30:192 Indo-pacific marine invertebrates 21:251 bioactive metabolites from 21:251 Induced skin tumor 29:76 by DMBA/fumonsin-B 1 29:76 by DMBA/mineral oil 29:76 by DMBA/okadaic acid 29:76 by DMBA/teleocidin B 29:76 by DMBA/TPA 29:76 by NOR-1/TPA 29:76 Inducible cyclooxygenase 25:47 inhibition of 25:47 Inducible nitric oxide synthase 25:47 inhibition of 25:47 Inductive action 23:579 of sonic hedgehog 23:579 Industrial applications 21:619 INEPT spectra 2:92,93 of 4-hydroxysapriparaquinone
5:36 of aquillochin 5:6 of artemisinin 5:27 of berberine 5:43,44 of colchicine 5:47 of damaran-20(S)-ol 2:92,93 of eupatorenone 5:30 of larreantin 5:10,11 of prionitin 5:31 of salvinolone 5:34,35 of sanguinarine 5:43 Infantile autism 30:376 hippocampal neurons in 30:376 Infantile convulsion 22:511,512,518, 519,521,535 Allium cepa L. for 22:511 Aneilema scapiflorum for 22:512 Arossostephium chinese L. for 22:518 Crossostephium chinese L. for 22:518 Desmodium pulchellum for 22:519 Ferula alliacea for 22:521 Ficus capensis for 22:521 role of HMG-CoA-Inhibitors in 22:250 Verbasum thapsus L. for 22:535 Infesting microorganisms 21:103 Infetroban 25:593 Inflammation 24:893-895;28:202; 30:192,224,225,732 COX-2 enzyme in 30:192 isoliquirtin in 24:893-895 pro-nociceptive prostaglandins in 30:192 role of free radicals in 30:224 role ofleukotrienes in 30:225 use of Artocarpus venenosa against 28:202 Inflammation mediators 30:225 leukotrienes as 30:225 Inflammatory activity 20:531 Inflammatory disorder 30:192 treament by COX-2 inhibitor 30:192 Inflammatory genes 30:319 COX-2 as 30:319 expression of 30:319
425 interleukin-2 as 30:319 interferon-), as 30:319 TNF-a as 30:319 Inflammatory pain 30:205,204 induction by formalin 30:205 inhibition by incarvillateine 30:204 Inflammatory skin condition 30:206 use ofbrein in 30:206 use of amyrin in 30:206 Inflexanin A 15:112,115 from Rabdosia inflexa 15:172 ~H-NMR of 15:122 Inflexanin B 15:112,117,124 from Rabdosia inflexa 15:172 IH-NMR of 15:124 Inflexarabdonin A 15:120 13C-NMR of 15:133 from Rabdosia inflexa 15:172 ~H-NMR of 15:126 Inflexarabdonin B 15:117 13C-NMR of 15:131 from Rabdosia inflexa 15:172 ~H-NMR of 15:124 Inflexarabdonin C 15:114 13C-NMR of 15:128 from Rabdosia inflexa 15:172 ~H-NMR of 15:121 Inflexarabdonin D 15:120 13C-NMR of 15:133 from Rabdosia inflexa 15:172 1H-NMR of 15:126 Inflexarabdonin E 15:115 13C-NMR of 15:129 from Rabdosia inflexa 15:172 1H-NMR of 15:122 Inflexarabdonin F 15:120 13C-NMR of 15:134 from Rabdosia inflexa 15:172 1H-NMR of 15:127 Inflexarabdonin G 15:115 13C-NMR of 15:129 from Rabdosia inflexa 15:172 ~H-NMR of 15:122 Inflexarabdonin H 15:115 13C-NMR of 15:129 from Rabdosia inflexa 15:172 ~H-NMR of 15:122
Inflexin 15:112,115 13C-NMR of 15:129 from Rabdosia inflexa 15:172 ~H-NMR of 15:122 Inflexinol 15:112,117 from Rabdosia inflexa 15:172 ~H-NMR of 15:124 Influence ofphytohormones 17:408,410 Influenza 30:407 therapy of 30:407 preventive medicines for 30:407 use of phytochemicals in 30:407 Influenza A treatment 27:108 role of amantadine 27:108 Influenza B 27:108 Influenza infection 27:103 Influenza virus 27:107,108;30:289,395, 407,408 enzyme mechanism of 27:114 in vitro 30:408 inhibitor of 30:395 representation of 27:107 Influenza virus replication 30:408 effect of sulphated polysaccharide (PS) 30:408 Infuscaside 2:280,281 Ingenane 12:233-245;25:243,246 synthesis of 12:233-245 Ingenane system 1:547 Ingenol 1:546,547,571;2:261;12:233245 IH-NMR of 12:234 synthesis of 1:547 synthesis of ring system 1:571 synthesis of 12:233-245 X-Ray crystallography of 12:234 Ingenol 20-hexadecanoate 29:103 activity in mam-2 bioassay system 29:103 Ingenol diterpenoids 17-hydroxyingenol-20-hexa-decanoate 25:543 ingenol-20-hexadecanoate 25:543 Ingenol type diterpenes 24:288 anti-tumor activity of 24:288 Ingol 2:261 Inhibitins 7:119 of aminoglycopyranoses 7:47
426
of 1 thio fI-D-galactopyranosides 7:48 Inhibition 7:47,48;9:581;23:239; 25:45-46,66,313,331,344,477,512, 615 of 4-(methylnitrosamino)-l-(3pyridyl)- 1-butanone (NNK) induced lung tumors 25:46 of 5-1ipoxygenase 25:47 of 12-1ipoxygenase 25:47 of 15-1ipoxygenase 25:47 ofadenylyl cyclase 25:532 of adjurant induced polyarthritis 25:46 of arachidonic acid 25:66 of arachidonic acid induced edema 25:46 offl-hematin aggregation 25:342,354 of bradykinin induced edema 25:46 of capsaicin induced edema 25:46 of carrageenan induced edema 25:46 of cotton pellet granuloma 25:46 of cycloxygenase 25:47 of Epstein-Barr virus early 25:46 of eukaryate signal transduction components 25:512 of falcipain 25:331 of heme polymerizations 25:348 of heme sequestration 25:348 of hemozoin 25:354 of histamine release 25:47 ofhepatocyte apoptosis 25:477 of human leucocyte elastase 25:47 of hylauronidase 25:47 of inducible cyclooxygenase 25:47 of inducible nitric oxide synthase 25:47 of DMBA/TPA induced skin tumor 25:48 of LDL oxidation 25:946 of lyso PAP acetyltransferase activity 25:615 4-( me thylni trosamino)- 1-(3-
pyridyl)- 1-butanone (NNK) induced lung tumors 25:46 of pisatin 12:399 of protein kinase C 23:239 Inhibition, of LTCa-release 27:691 Inhibition, of PGE2-release 27:690 from peritoneal macrophages 27:690 Inhibitor 23:68;24:1085;25:542,544, 546;30:836 of 1AA oxidation 25:657 of calmodulin 25:706 of CDPK 25:542,546 of cell adhesion 24:1085 of EFEs 30:836 of enzymes 9:515 of gram-positive bacteria 23:68 of human synovial PLA2 25:697 ofkinesin motors 25:695 of PKA 25:541 of PMA 25:938 of protein phosphatases 25:707 ofsterol biosynthesis 25:303 of vitamin-D-metobolism 9:515 offl-hemetin 25:357 Inhibitory action 27:402 of chitosan 27:402 Inhibitory activity 12:332;21:98,193, 263,270,312,398,430,585,589,591, 594,643,659,670, 673,675,690 ;23:59, 216,808;26:217;28:481 ;30:629 against bone resorption 21:720, 721 against H§247 21:719 against Staphyllococcus aureus 30:629 mechanism of action of 30:225 of (-)-(8,Sa-di-epi-swainsonine 12:325 of (-)-swainsonine 12:327 of (+)-castanospermine 12:332 of benzalmalonates 9:225-227 of honokiol 26:217 of inumakilactone A 28:481 of inumakilactone/3 28:481 of inumakilactone C 28:481 of machilin A 26:217 of matairesinol 26:217 of mitogen-induced arctigenin
427 26:217 of nagilactone A 28:481 ofnagilactone B 28:481 ofnagilactone C 28:481 ofpodolactone A 28:481 ofpodolactone B 28:481 ofpodolactone C 28:481 ofpodolactone D 28:481 ofpodolactone E 28:481 of rifamycine-type ansamycine antibiotics 23:59 of taurospongin A 23:216 on blastogensis 26:217 Inhibitory activity, against human epidermoid carcinoma 24:848 Inhibitory effect 21:695,701,719; 23:311-316,318,445,673,721; 24:215-264,849;25:55 ;27:437; 30:396,594,801 ofcelafoin C-1 23:673 ofcelafolin D-2 23:673 in vitro 30:396 of ailanthone 23:318 ofailantinol A 23:315 ofalienanin B 23:445 of amarolide 23:315,318 ofbrucein D 23:312 ofbudlejasaponin IV 27:689, 690,691 of carp extract 27:440,689 ofcelafolins B-2 23:673 ofcelafolins C-1 23:673 ofcelafolins D-2 23:673 on chemical carcinogenesis 24:215-264 of chitosan 27:437,440 of curcumine 23:316 of DAGO 30:801 of dermorphin 30:801 of dihydroagarofuran sesquiterpenes 23:673 of flavonoids 24:215-264 of ginseng saponins 27:423 of H+,K+-ATPase 21:701,719 ofHernandia sp. 30:594 ofmaytansinoids 23:721 of morphine 30:801 of natural quassinoids 23:311 ofneoquassin 23:314,318
ofnigakihemiacetal D 23:318 ofnigakilactone F 23:313 of picrasin B 23:313 ofrotenoids 24:215-264 ofsandrosaponin I 27:689,690, 691,693 of SDB 21:695 of semi-synthetic quassinoid 23:311,319 of shinjudilactone 23:318 of shinjulactone A 23:315 of steroids 24:215-264 oftriptofordin F-2 23:673 oftriptogelin A-1 23:673 oftriterpenoids 24:215-264 ofyadanziolide C 23:312 of ~t-agonists 30:801 on bone resorption 21:702 on croton oil-induced inflammatory edema 25:55 on Epstein-Barr virus activation 24:849 on gastric acid secretion 21:701 on H+,K+-ATPase 21:701 on HHPA 25:55 on HIV replication 30:396 on HSV-1 replication 21:695 on TPA 25:55 Inhibitory mechanisms 30:318 of emodine 30:318 Inhoffen-Lythgoe diol 1:591,592 synthesis of 1:592 I-nitropyrene (I-NP) 22:623,624 Injection techniques 9:457 Inlet systems 2:45 Innzeylanine 26:850 INOC reaction 1:480,481 Inones 25:125 Inosine (x-L-fucopyranoside-H 23:199 Inosine H 23:199 Inosine monophosphate 22:259 myo-Inositol 7:181;13:190;18:391; 19:352-353 D-chiro-Inositol 18:439 Inositol (cyclohexanhexaol) 7:37 myo-Inositol 1-phosphate 11:216,217 by myo-inositol- 1-phosphate synthase 11:216,217
428
from glucose-6-phosphate 11:216,217 L-chiro-Inositol 2,3,5-trisphosphate 18:416 Inositol lipids 22:21 Inositol phosphates 18:393-451 Myo-Inositol triflates 18:439 Inositol triphosphate 22:666 Inositol triphosphate (IP3) 25:483,487, 488,509,524 radioactive 25:487 Inositol- 1,4,5-triphosphate 22:21 Inositol- 1,4,5-triphosphate (IP3) 25:522, 547,548 Myo-Inositol- 1-phosphate synthase 11:216 from beef testes 11:216 from Lilium longifolium 11:216 myo-mositol 1-phosphate by 11:216,217 Inostamycin 15:453-456,461 Inouye's photochemical route 12:198 Inqayi 23:656 Insect antifeedant activity 23:319 of natural quassinoids 23:319 of semi-synthetic quassinoid 23:319 Insect cell-based bioassays 29:30 cyasterone activity in 29:32 2-deoxy-20-hyroxyecdysone activity in 29:32 14-deoxymuristerone A activity in 29:32 2 [3,3[3-dihydroxy- 5 [3-cholest-7en-6-one activity in 29:32 3 [3,14cx-dihydroxy-5 [~-cholest-7en-6-one activity in 29:32 ecdysone activity in 29:32 3 [3-hydroxy-5 [3-cholest-6-one activity in 29:32 20-hydroxyecdysone activity in 29:32 inokosterone activity in 29:32 Kc cell bioassay as 29:30 makisterone A activity in 29:32 muristerone A activity in 29:32 podecdysone A activity in 29:32 ponasterones activity in 29:32
213,3[3,5[3,14cx-tetrahydroxycholest-7-en-6-one activity in 29:32 2[3,3[3,25-tridihydroxy-5 [3cholest-6-one activity in 29:32 viticosterone E activity in 29:32 Insect control 21:611 Insect juvenile hormone analogues 14:395-397 from thujone 14:391-397 synthesis of 14:391-397 via [3-1actone route 14:395-397 Insect neuropeptides 9:487-493 Insect pheromones 11:415-417 via diisopropylethanediol esters 11:415-417 via pinanediol esters 11:412-414 synthesis of 3:270-273,493,494; 11:412-417 Insect repellant 5:757 Insecticidal activity 18:229,704;21:252, 254,262,266,267,269,270,271,278, 285,379,595,611 ;23:666;667,670, 677,678;24:25,799,845,866;26:231, 232,426,471,479,485;28:477; 30:153-154,695 biological activity 24:25,799,845 bioassay of 24:866 of 14-epi-ponolactone A 28:477 of anacardic acid 30:153-154 of celastrus angulatus 23:666 ofhallactone A 28:477 ofhallactone B 28:477 of lemon juice phenolics 23:748 oflollo rosso 23:759 ofnagilactone A 28:477 ofnagilactone C 28:477 ofnagilactone D 28:477 ofnagilactone E 28:477 ofpodolactone A 28:477 ofpodolactone C 28:477 ofpodolide 28:477 of quinone methides 30:695 of red lettuce anthocyanins 23:760 of red onion anthocyanins 23:762 of Romaine lettuce phenols
429
23:761 ofsellowin A 28:477 of sesquiterpene alkaloids 23:678 of sesquiterpenes 23:667,670 Insecticidal assay 21:273,276,281,284 Insecticidal effects 26:852,1136 of ryanodol-type diterpenes 26:852 of isoryanodol-type diterpenes 26:852 Insecticidal properties 21:225 Insecticidal sesquiterpenes 23:668 from Euonymus bungeanus 23:668 Insecticidal Stemona alkaloids 21:759 Insecticides 7:395-397;21:110;28:390 used of essential oil 28:415,390 Insect-plant relationship 27:384 Insomula 21:101 Insositol- 1,4,5-triphosphate (IP3) receptor 25:534 Insularoside 26:321-323,325,327,333, 343 Insulin 2:25 bovine 2:23-25 gene synthesis 4:271 isotopic distribution of (MMH +) 2:25 Insulin B chain 2:23-25;25:390 Insulin signalling activated protein kinase 25:522 Insulin-responsive protein kinase (PKB) 25:517 Integerrimine 1:272-274 synthesis of 1:272-274 Integerrinecic acid 1:263-267 synthesis of 1:263,264,266,267 Integramycin 28:147 as HIV-integrase inhibitor 28:147 Integrase 30:226 cleaveage of 30:226 role in HIV 30:226 Integrins 27:825 Inter alia 26:481 Interaction of THS 25:468 with a-TNF 25:468 Interconversion 27:336 of abscisic acid ring 27:336,338
Interferon 4:273;25:519 LPS induction of 4:199 Interferon gamma (IFN-~,) 30:689 inhibitory effect on 30:689 production of 30:689 Interferon production 12:390 by human cell cultures 12:390 protein kinase in 12:390 Interferon 3' (IFN-?,) 25:431,464,477; 26:951 Interferones (INFs) 24:489 Interferon-ct-[3 and y 20:531-533;26:951 Interiotherin A 26:197,223,224 Interiotherin B 26:197 Interleukin 25:271,540;26:951 Interleukin I 5:388 Interleukin I induction 4:197 by LPS 4:197 Interleukin-1 22:110;30:689 by synovium 30:689 production of 30:689 Interleukin-2 25:536 Interleukin-2-dependent (IL-2) 25:271 Interleukin-6 cytokine family 25:717 Interleukin-8 25:711 (+)-Intermedeol 14:449-451 biological activity of 14:450,451 from ot-agarofuran 14:453 from Bothriochloa bladhi 14:450 from Bothriochloa glabra 14:450 from Bothriochloa intermedia 14:449-451 from Bothriochloa insculpta 14:450 from Carthamus lanatus 14:450,451 from Citrus paradisi 14:450 from Cymbopogon flexuosus 14:450,451 from (-)-7-epi-cyperone 14:452, 453 from Senecio amplexicaulus 14:450 from Velocitermes velox 14:451, 452 synthesis of 14:456-465 total synthesis of 14:452,453
430 (+)-Intermedeol 14:450,451;23:800 biological activity of 14:450,451 Intermedine 1:269 Intermedine N-oxide 1:270 Intermolecular additions 24:201 Intermolecular aldol condensation 10:318-320 Intermolecular cationic [5+2] cycloaddition 8:160,161 Intermolecular cyclization 6:59 spirosystems construction by 6:59 Intermolecular Diels-Alder cycloadditions 24:33 Intermolecular Diels-Alder reaction 6:549,550;24:768 Intermolecular Knoevenagel type cyclization 24:33-40 Intermolecular Michael reaction 14:552 enantioselective 14:552 Intermolecular O-alkylation 8:198,199 Internal aldolization 6:81 in (+)-2-isocyanopupukeanane synthesis 6:81 Internal alkylation 6:74 in (+)-9-isocyanopupukeanane synthesis 6:80 Internal Diels-Alder reaction 6:86,87 International council of harmonization 27:304 Internuclear distance 2:60,61 and cross-relaxation rates 2:60, 61 from NOE rations 2:61 Interproton distances 2:70,71 Intersystem crossing 22:214 Intestinal calcium transport 30:484,497 assay for 30:497 of lot,25(OH)2D3 30:497 role of vitamin D2 in 30:484 Intestinal diseases 30:224 role of free radicals in 30:224 Intestinal worms 1:435 Intraerythrocytic antimalarial activity 25:343 Intraerythrocytic cycle 25:329 Intraerythrocytic phase 25:327,328,329 Intramolecular [2+1 ] cycloaddition 6:52
Intramolecular [2+2] cycloaddition 12:193 Intramolecular [2+2] photoaddition 12:210 Intramolecular [2+2] photocycloaddition 6:69 Intramolecular [4+ 1] pyrroline annulation 1:250 Intramolecular [4+2] cycloaddition 6:85 in (+)-sinularene synthesis 6:85 in 7,20-diisocyanoadociane synthesis 6:86,87 olefin tropolone 5:799 Intramolecular 1,3-dipolar cycloaddition 12:318 Intramolecular acetalization 14:60 Intramolecular acylinitroso Diels-Alder reaction 1:386 Intramolecular addition 10:3-11 to chiral sulfoximines 10:3-11 to chiral vinyl sulfoxides 10:3-11 Intramolecular Alder ene reaction 10:222,224 Intramolecular aldol condensation 6:549,550,231 ;15:235,269,297; 24:779,780 Intramolecular aldol cyclization 6:36, 66,67;18:633 in poitediol synthesis 6:36 in (-)-upial synthesis 6:66,77 Intramolecular aldol reaction 24:15,24, 25;26:111 Intramolecular alkylation 6:42,43; 8:225-233,540,558;24:13 Intramolecular amidoalkylation 1:246 Intramolecular aminomercuration 10:532,540;12:333 Intramolecular arylation 12:447-452 Intramolecular base-induced rearrangement 14:374 Intramolecular C-alkyation 24:9-11 Intramolecular carbenoid displacement 1:259 Intramolecular carbocyclization 24:15 Intramolecular chelation 14:53 Intramolecular Claisen condensation 18:299 Intramolecular coupling 6:546,547
431 Intramolecular cyclization 2:282; 21:36,37,398 nickel-catalyzed 2:282 spirosystems construction by 6:59 in (+)-9-isocyanopupukeanane synthesis 6:82,83 Intramolecular cycloalkylation 6:6; 24:9,10 in (+)-amjitrienol synthesis 6:53 in tricyclic natural products synthesis 6:74 Intramolecular cyclopropanation 6:73, 74 Intramolecular Diels-Alder reaction 4:601,602 betaenone B by 4:601,602 coronafacic acid by 4:596,597 diplodiatoxin by 4:600-602 endo rule 4:18 fused versus bridged product 4:565 in biosynthesis 4:616,621 kinetic selectivity 4:601 solanapyrone A by 4:598 stereoselectivity 4:595,596 Intramolecular displacement reaction 12:311,344 Intramolecular diyl trapping reaction 6:46 Intramolecular double Michael addition 8:418 Intramolecular ene reaction 24:29,30, 759,760 Intramolecular glycosylation 14:236 Intramolecular heteroene reaction 12:295 Intramolecular Homer-Emmons condensation 12:341 Intramolecular Homer-Emmons reaction 24:15 Intramolecular Michael addition 6:70, 71 in (+)-sanadaol ([3-crenutal) synthesis 6:70,71 Intramolecular Michael cyclization 14:552 of an acyclic compound 14:552
Intramolecular Michael reaction 6:178, 184,196 asymmetric 14:551-567 by chiral enamine 14:551-567 enantioselective 14:551-567 Intramolecular oxidative coupling 6:480 Intramolecular photocycloaddition 6:34, 35,54 in (+)-epi-precapnelladiene synthesis 6:34,35 in isoamijiol synthesis 6:54 Intramolecular Pinner reaction 15:415 Intramolecular Prins reaction 24:64,65 Intramolecular radical-induced carbocyclization 24:15-18 Intramolecular reaction 11:45-47 (2+2) cycloaddition 11:45-47 [4+4] cycloaddition 11:17 1,3-dipolar cycloaddition 11:283-285 aldehyde-ketophosphonate condensation 6:264,265 aldol condensation 11:90,108, 113,115;12:82 alkylation of 8:176,177 amidoalkylation 10:108 amidomercuration 12:281 aminolysis 12:279 annulation 10:407 asymmetric hydrosilylation 13:72 azido-olefin cyclization 13:447, 448 Biellmann coupling 10:6-10 C-C bond formation 12:65 cross-coupling reaction 10:163 cross-aldolisation 12:289 cyclization 10:631-633;12:281, 327 dicarbonyl coupling 11:345, 364-367 Diels-Alder reaction 10:51,52, 155,409;11:11,92,93,99,108; 13:108-115;14:745 double cyclization 10:83 displacement 12:347 ene reaction 11:91-108 epoxide alkylation 14:746 esterification of 8:176
432
etherification 12:65 Friedal-Crafts acylation 10:131 Friedal-Crafts reaction 10:312, 313 hetero Diels-Alder reaction 6:449 Horner-Emmons condensation 10:13-17 imino Diels-Alder approach 14:732,733 Michael addition 11:312;14:736 Michael reaction 9:435,437; 10:51,52;13:180-443 mixed Claisen condensation 12:104 Mukaiyama condensation 10:181,182 N-acyliminium ion cyclization 11:284,285 nitrile oxide cyclization 14:745 nitrone cycloaddition 14:744 O-C bond formation 12:83 P ~-allyl Pd alkylation 10:10-13 photocycloaddition 11:20 photoreduction 12:283 proton transfer 12:102 Pummerer reaction 10:682 rhodium II mediated 10:407 ring contraction 11:42,43 ring-opening 12:83 Sakurai reaction 10:182 S-alkylation 13:145 SE' additions 10:17-25 SN2 cyclization 12:85 SN'-process 11:323 stereoselective cyclization 10:92 translactonization 13:159 trans-sulfenylation 12:69,72 Ulmann reaction 10:640 Wadsworth-Emmons reaction 12:328 Wittig Homer reaction 11:152, 153 Wittig reaction 13:601 Wittig-Horner cyclization 12:292 Wittig-type reaction 12:147 cz-diazo-13-keto ester synthesis 10:407
Intramolecular reduction 14:153 Intramolecular reductive amination 12:316 Intramolecular reductive coupling 6:48, 52,54 in (-4-)-A9(12) capnellene synthesis 6:48 in dolasta-1 (15),7,9-trien-14-ol synthesis 6:52 in isoamijiol synthesis 6:54 Intramolecular ring closure reaction 6:492 Intramolecular trans-ketalization 10:211 Intramolecular type I-"Mg-ene" reaction 6:45,46,76-78 in (+)-A 9(12) capnellene synthesis 6:45,46 in (+)-sinularene synthesis 6:76,77 Intramolecular vinylogous aldol reaction 24:14,22,23 Intramolecular Wittig reaction 1:234, 235,573 Intramolecular rt-alkylation 6:184,185 Intrapetacin A 28:66 anti-fungal activity of 28:66 Intrapetacin B 28:66 anti-fungal activity of 28:66 Intrasinusoidal hematosis 25:464 Intrinsic activity 30:596,816 in vivo 30:596 of alkaloids 30:596 of central opioid receptors 30:816 of DER 30:816 of glycopeptides 30:816 Introns 13:290 Inula britannica 29:90 lnula cappa 5:678 Inula crithmoides 5:728 Inula nervosa 19:125 Inula viscose 29:87 Inuviscolide 29:90 activity in TPA assay system 29:90 Inverse electron demand 4:579,580,604 in Diels-Alder reaction 4:579,
433
580,604 using enamines 4:604 using enols 4:604 using ketone dithioacetal 4:604 Inversion 1:459 of alcohol center 1:204,205,456, 457,459 Mitsunobu protocol 1:459 Invertase inhibition 21:593 Invictolide 1:681-683;3:272,273 ent-Invictolide 16:711-712 synthesis of 16:711-712 Iodination 27:751 oftyrosine 27:751 Iodine pentoxide 1:51 oxidation of indoles to acylindoles 1:151 Iodine-catalyzed 6:139-141,153,154 stereomutation mixtures 6:139-141,154 isomerization 6:141,153,154 5-Iodo ketones 8:245 4'-Iodo-4'-desoxydoxorubicin 14:21 w-I o do alkyl-2-phenylthiomethyl-4,6dimethoxy-benzoate 8:176,177 p-Iodoanilide 23:55 Iodobenzene diacetate 4:331 c~-hydroxylation of ketones 4:331 Iodocarbonate 11:361 enantiomerically pure oil from 11:346,347 with p-toluene sulfonic acid monohydrates 11:346,347 8-Iodocoumarin 4:372 Iodocoumarin 4:396,398 with copper acetylide 4:396,398 Iodocyclisation 10:391 of alkene 10:391 Iodocyclocarbamation 4:126 Iodoetherification 10:21,24 Iodolactone 8:153,154 Iodolactonization 1: 199,204-206, 254,526;13:208,622 by m-chloroperbenzoic acid 11:358,359 by iodine 11:358,359 Iodomagnesium salt 14:750
Iodomethylphenyl sulfide 4:463 alkylation with 4:462 5-Iodopentadienoic acid 21:393 p-Iodophenyl 4-O-triflygalactopyranosylglucoside 8:343,345 D-Iodopyranoside 19:367 Iodosobenzene 14:780 N-Iodosuccinimide 26:1162 Iodosulfonation 21:384 Iodotrimethyl silane 1:390;11:528 cyclization with 11:109 Iodotyrosine 23:241 125I-Iodotyrosine 25:373 Ion channel blockers 22:16 Ion channels 21:73,98 alkaloids with 21:3-111 Ion gradient generating ATPase 25:512 Ion-channel complex 21:18 Ion-exchange column chromatography 19:519 Ionic cycloaddition 5:793 Ionization energy 2:3 Ionoization behaviour 21:556 of procyanides 21:556 (+)-Ionomycin 16:715-716 synthesis of 16:715-716 Ionomycin 3:58 ~-Ionone 13:328,330;20:576,584; 28:406 acaricidal properties of 28:406 [3-Ionone 17:612 ~-Ionone 20:589 (R)-(+)-ct-Ionones 20:584 Ionophone A23189 25:274,275,940 Ionophore 3:273-277;21:414;25:374 synthesis of 3:273-277 Ionophore activity 4:93;18:857 Ionophore X-14547 A 10:425 synthesis of 10:425 Ionophores 16:711 Ionophoric antibiotics 21:303 IP3-Ionositol-l,4,5-triphosphate 25:516 Ionotropic glutamate receptors 25:528 Ionotropic serotonin receptors 25:529 Ionotropic receptor 25:528;30:192,193 heat-activated channel TRPVI type 30:193 role in nociceptor depolarisation
434
30:192 role in tetrodotoxin-resistant sodium channels 30:193 role in vanilloid receptors 30:193 TRPM8 type of 30:193 "Ionoxide" principal 14:424,425 Iophotoxins 18:697,698 IP3 receptors Ca 2+ channel 25:534 IPa-gated Ca 2+channels 25:517 IPa-induced release of Ca 2+ 25:488 IPa-Inositol- 1,4,5-triphosphate 25:516 Ipalbidine 1:283,293,363-365 synthesis of 1:283,293,363-365 Ipalbine 1:362 Ipc2BC1 8:476 as chiral reducing agent 8:476 IpcBH2 8:475,476 as chiral reducing agent 8:475, 476 Ipecacuanha alkaloids 7:444,92 Ipolamiide 7:458,459,463;29:84 activity in CRG, BRK, HST assay systems 29:84 Ipolamiidol 7:467 (+)-Ipomeamarone 15:236,237 Ipomeamarone 15:249 biosynthesis of 15:249 synthesis of 3:57-58 (-)-Ipomearone 15:237 Ipomine 1:362 Ipomoea 2:369 tissue cultures of 2:369 Ipomoea alba 1:362 alkaloids of 1:362 Ipomoea batatas 29:604 lpomoea cairica 26:223 Ipomoea hederaceae L. 22:523 for epilepsy 22:523 Ipomoea hispida 22:523 for epilepsy 22:523 Ipomoea muricata 1:362 Ipomopsis aggregata 23:96 lponuga 27:250 IPP-DMAPP isomerase 7:108,109 Ipratropium 22:738 S-(+)-Ipsdienol 16:242 Ipsenol 1O: 188 synthesis of 10:188 Ipstypographus 27:384,385
IR spectrum 27:177 of sanguilutine free base 27:177 Ircenals 24:573,615,667,669 anti-bacterial activity of 24:573 anti-leukemic activity of 24:573 Ircinia dendroides 25:885;28:684 lrcinia fasiculata 28:673 fasiculatin for 28:673 Ircinia sp. 21:260;25:688,703,705,709; 28:670,714 Ircinia spinulosa 28:676;29:694 brine shrimp toxicity of 28:676 2-prenylhydroquinones of 28:676 Ircinia sponges 25:695 Ircinia variabilis 28:673 22-O-sulfates of palinurin from 28:673 sulfate esters from 28:673 Ircinia wistarii 6:8 ircinianin from 6:8 wistarin from 6:8 Ircinianin 4:618,619 biosynthesis of 4:618,619 from Ircinia wistarii 6:8 from methyl g-oxosenecioate 6:8 synthesis of 6:8 Irciniasulfonic acid 28:714 reverses multidrug resistance 28:714 Ircinin 25:688 (-)-Ireland alcohol 14:119,120 synthesis of 14:119,120 Ireland approach 12:16,17 Ireland-Claisen rearrangement 3:268, 614;10:416,417,424-425,429;18:230, 231,259;20:67,1227 in nonactic acid synthesis 3:228 Kazmaier's modification of 26:1227 ofallylic glycolate esters 10:437 ofsilyl ketene acetal 10:423 Iridium black 6:83,85 selective hydrogenation with 6:83,85 Iridium complexes 21:386 Iridodial 7:441,442 Iridodiols 7:442,482 Iridoid boschnialactone 8:133
435
Iridoid glucoside 6:529,114,439,440, 445,457;7:461,469,472,475 chemistry of 7:455-486 classification 7:454,455 nomenclature 7:451,452 structural characteristics 7:453, 454 Iridoid precursor 6:503,529 Iridoids 7:439-492;24:799,510-521 13C-NMR spectrum of 7:486,487 diuretic activity of 7:490 IH-NMR spectrum of 7:486,487 4-hydroxymethyl-substituted iridoids 7:467 5-hydroxy-substituted iridoids 7:463,464 acid catalysed transformations 7:456-468 acid hydrolysis of 7:462 aglycone 7:458,461,465,486 analgesic activity of 7:490 antidote for ot-amanitin poisoning 7:490 antileukemic activity of 7:490 antiphlogistic activity of 7:490 antitumor activity of 7:490 as chiral templates 7:468 biogenesis of 7:488,489 biological activity of 7:490 bisiridoids 7:443 chemistry of 7:439-492 choleretic activity of 7:490 chromatography of 7:488 definition of 7:439 diuretic activity of 7:490 gentiopicroside type 7:443 glycosides 7:439,457,461,468, 469,472,475 glycosylation of 7:488 hypotensive activity of 7:490 trifluoromethane-sulfonate (TMS-triflate) 7:488 hepatoprotectivity of 7:490 interconversion of 7:469 iridodiols 7:442 laxative activity of 7:490 miscellaneous-type 7:442 NaBH4 reduction of 7:466 oleuropein type 7:443
partial synthesis of 7:478-486 plumeria-type 7:442 secoiridoids 7:442,443 secologanin type 7:443 sedative activity of 7:490 simple 7:440,441 stability of dihydropyranic ring 7:455 synthesis of 7:487,488; 16:289-320 uterine contracting activity of 7:490 valeriana-type 7:442 Iridolactam alkaloids 6:503,529 Iridolactam derivatives 6:522-527 Iridomyrmecin 7:441,442;16:289; 20:70,74 Iridomyrmecin derivatives 7:476,477 Iridomyrmex humilis 5:223,225,240, 241,245,253 Iridomyrmex nitidus 5:222-224,233,253 Iridomyrmex purpureus 5:222,224,233, 253 Iridomyrmex rufoniger sp.gr. 5:223, 237,253 Irilin A 22:473 Irilin B 22:473 Irilin C 22:473 Iris germinica 10:152 Iris japonica 26:433 Iron pentacarbonyl 14:689,690 Iron responsive element 26:951 Iron tricarbonyl derivatives 1:572 acylation of 1:572 oftropone 1:572 [3-Irone 10:152 lrpex lacteus 26:439,468 Irreversible cytotoxicity 15:447 Irreversible inhibitors (suicide substrates) 7:36-40 Irritable bowel syndrome 30:368 role of serotonin (5-HT) 30:368 Irritant terpenoids 2:287 from liversorts 2:287 Irumamycin 5:467-471 Irumanolide I 5:599 Irumanolide II 5:599 Iryanthera lancifolia 22:356 dihydrochalcones from 22:356
436
flavonolignoids from 22:356 tocotrienols from 22:356 Iryanthera sagotiana 22:355 Isatis tinctoria 26:632 Ischaemia reperfusion 22:438;25:61 O, 614 (+_)-ent-Iscoent-Isocopal-12-ene- 15,16dial 6:119-122 synthesis of 6:119-122 ISCOMs 21:648,650 Ismine 20:356,369 Iso- 1-cytochrome 18:915,916 Iso-l-cytochrome C 18:832,838 Iso-6-canavaline 20:486 Iso-6-cassine synthesis 29:419 by stereodivergent process 29:419 Isoacronycine (pyrano[3,2-b] acridin-6one) dervatives 13:348,356 E-Isoafrol 8:160 Isoagatholactone 1:56,57,107,108,662 synthesis of 1:662 from (+)-labda-8(20), 13-diene15-oic acid 6:65,57 from Spongia officinalis 6:56, 107 (+)-Isoagatholactone 6:56,57 from (+)-Isoagatholactone 6:56, 57 from ent-methyl isocopolate 6:56,57 synthesis of 6:56,57 (-)-Isoagatholactone 6:57 synthesis of 6:57 Isoagatmic acid 6:107,108 S-Isoajmalicine 9:171 Isoajmaline 9:183,185,403 Isoalatol 18:745 (+)-Iso-allamandicin 16:301 synthesis of 16:301 Isoalliin 23:458,461 Isoalvaxanthone 28:230 biological activity of 28:230 (+)-Iso-Ambrox 14:420-425 synthesis of 14:420-425 Isoamericanol A 26:270 Isoamijiol 6:53,54 Isoampelopsin F 26:568 Isoamyl acetate 25:129
Isoamylases 10:498 Isoanacardic acid 9:371 Isoanacardic aldehyde 9:370 Isoannonacin- 10-one 17:270 Isoantibodies 29:542 antigen of 29:542 synthesis of 29:542 (+)-Isoaplysin-20 1:663,664 synthesis of 1:663,664 Isoaplysin-20 6:56 (_)-Isoaplysin-20 6:56,57 Isoaquillochin diacetate 5:7,8 Isoarcapillin 227 Isoastragaloside I 25:193 Isoavenaciolide 19:485 synthesis of 3:260,261 Isobaccharin 30:737 structure of 30:737 Isobaccharinol 30:736 structure of 30:736 Isobacteriochlorins 9:591,597,604 Isobalchanolide 7:231 Isobatzeiline A 25:822,790 Isobatzelline B 25:822,790 Isobatzeiline D 25:822 Isobazellines 25:707 Isobergapten 22:539 Isobetanidine 20:724,731 (+)-Isoboldine 16:509,512 Isoboldine 18:58 Isobonafousine 5:128 Isoborneol 25:154 (+)-Isobornyl acetate 4:645,646 remote oxidation of 4:645,646 Isobrafouedine 6:172 biosynthesis of 6:521 spectral data of 6:403-506 from Strychmos dinklagei 6:503 Isobrucein 5:38-41 Isobrucein-A 7:396,397,72;23:304 Isobrucein-B 7:374,381;23:285,304,313 Isobrucine 26:1051,1052 Isobrucine-N-oxide 26:1051,1052 Isobrugierol 7:193,194 8~-Isobutycyloxyestafafin 27:578 Isobutyl (2E,4E)-2,4,8-nonatrienamide 10:151 Isobutyl (2E,4E, 8Z)-2,4,8-decatrienamide 10:151
437 Isobutyl (2E,4E,8Z)-2,4,8-eicosatrienamide 10:151 Isobutyl (2E,4E,8Z, 10E)-2,4,8,10dodecatetraenamide 10:152 Isobutyl chloroformate 22:281 Isobutylamides 21:378 Isobutylamine 21:378 Isobutyl-methoxy pyrazine 13:320 Iosobutylmethylxanthine 25:275 6-Isobutyloxycarbonyl derivative 25:829 Isobutyrate 11:197 in Streptomyces cinnamonensis 11:197 monensin A with 11:197 [1-13C] Isobutyrate 5:608 Isobutyric acid 22:210 N-Isobutyrolycycloxobuxine 2:205 N-Isobutyroylcycloxobuxidine-H 2:205 Isobutyryl CoA 11:197 in Streptomyces cinnamonensis 11:197 interconversion of 11:197 stereochemical 11:197 Isocajucarinolide 29:100 activity in TLO assay system 29:100 (23R)-23H-Isocalysterol 9:38 (24S)-24H-Isocalysterol 9:38,44,45 (23S)-23H-Isocalysterol 9:38,45 from Calyx podatypa 9:38 2-Isocaproyl-3R-hydroxymethyl-),butyro lactone 18:700 Isocarbacyclin 1:639-641 enantioselective synthesis of 1:639-641 synthesis of 14:509 (+)-Isocarbacyclin 6:315 synthesis of 6:315 preparation of 16:388 Isocarotene 30:544 (+)-Isocorydine 30:564 5,6-dimethoxy-n-methylphthalimide 30:563 Isocaryophyllene 3:73,74,84-89 synthesis of 3:73,74,84-89 6-Isocassine 9:50,53 Isocedranes 13:41 Isocedranol 15:270
5-Isocedranone 5:791,792 Isocedrene 13:46 6-Isocedrol 5:789 Isocelorbicol 18:743 2-Isocephems 12:126 antibiotic activity of 12:126 Isochiloscyphone 18:614 Isochlorogenic acid 22:346;23:740 Isochlorogenic acid 'a' 23:744 Isochlorogenic acid 'b' 23:744 Isochlorogenic acid 'c' 23:744 Isochromazonarol 15:299 Isochromophilones 25:797 (2R,3S)-Isocitrate 20:872 Isococculidine 25:528 Isocodonocarpine 9:53,54,57 epi-Isocomene 3:41 [3-Isocomene 3:6,20 Isocomene 3:6,9,15,21,24,60;13:4-6 synthesis of 3:6,9,15,21,24,60 ISOCOMS (Immunostimulating complexes) 24:163 (+)-Isoconcinndiol 6:26 from Laurencia snyderae 6:26 (+)-14-epi-Isocopal- 12-ene- 15,16-dial 6:108,110 (+)-ent-Isocopal- 12-ene- 15,16-dial 6:108,110 (+)-14-epi-ent-Isocopal- 12-ene- 15,16dial 6:111,119,122 synthesis of 6:119-112 ent-Isocopalane 6:108 Isocopalane-type diterpenes 6:119-122 (+)-Isocorynoline 14:785-789 from corysamine 14:785-789 oxidation of 14:785-789 synthesis of 14:785-789 through enamine-aldehyde cyclization 14:785-788 Isocoumarins 7:266,267,270,287; 20:283;23:343 Isocrepidamine 12:286 Isocrispatine 1:272,273 Isocurcumenol 29:90 activity in HPT assay system 29:90 Isocyanate intermediate 27:330 Isocyanide
438 Isocyanides 12:113;21:329-331,346, 349-367 by alkylation of silver cyanide 12:113 by carbylamine reaction 12:113 by dehydration of N-minosubstituted formamides 12:113 from diphosgene 12:113 from phosgene 12:113 from triphosgene 12:113 isodendrocrepine 12:286 from dendrocrepine 12:286 in nudibranchs 21:358 Isocyanide group 21:349 biosynthesis of 21:349 lsocyano derivatives 21:221 10-Isocyano-4-cadinene 21:366 2-Isocyanoallopupukeanane 21:354,365 9-Isocyanoneopupukeanane 21:351,356 9-Isocyanopupukeanane 17:16;21:365 2-Isocyanopupukeanane 21:349,351 (-)-4-lsocyanopupukeanane 21:354 (+)-9-Isocyanopupukenanane 6:82-83 by Claisen rearrangement 6:82-83 by intramolecular cyclization 6:82-83 by internal alkylation 6:80 by selective hydrogenation 6:83 from bicarbocyclic lactone 6:80 from 3,5-dimethyl-2-cyclohexan1-one 6:82-83 from hydrindanone 6:80 from Phyllidia varicosa 6:79 synthesis of 6:80,81 (+)-2-Isocyanopupukenane 6:81 by internal aldolization 6:81 from becarbocyclic lactone 6:80 from 2-ketopupukenanone 6:82 from Phyllidia 6:80 synthesis of 6:80,81 3-Isocyanotheonellin 21:366 2-Isocyanotrachyopsane 21:354 Isocycloamphilectanes 25:853 (+)-Isocycloeudesmol 6:41,42 by olefin-ketocarbene cyclization reaction 6:41 relation to cycloeudesmol 6:41
from Laurencia nipponica 6:41 synthesis of 6:41,42 Isodactylol 3:91-93 synthesis of 3:91-93 epi-Isodasycarpidone 1:58 synthesis of 1:58 Isodasycarpidone 1:58 synthesis of 1:58 Isodaucane 25:848,850 Isodeacetyl uvaricin 18:221 from Annona bullata 18:221 from Uvaria narum 18:221 hemi synthesis of 18:221,222 Isodeoxybouvardin 10:640-642 synthesis of 10:644,645 Isodeoxybouvardin methyl ether 10:640-642 synthesis of 10:644,645 Isodeoxypodophyllotoxin 26:93,213 cytotoxicity of 26:213 Isoderrone 28:228 biological activity of 28:228 Isodesoxypicropodophyllin 18:588 Isodesoxypodophyllotoxin 5:485 Isodictya setifera 25:828 Isodidemnin-1 5:422-426;10:251,253, 262,263 Isodihydrofutoquinol A 8:169,170 synthesis of 8:169,170 Isodihydrofutoquinol B 8:170 Isodihydroiridodiol 3:193 Isodihydronepelactone 16:289 Isodiospyrin 7:423 Isodityrosine 10:629-669 synthesis of 10:630 Isodocarpin 15:174 from Rabdosia ragosa 15:174 Isodomedin 15:174,175 from Rabdosia pseudo-irrorata 15:174 from Rabdosia umbrosa 15:175 from Rabdosia umbrosa var. hakusanensis 15:175 from Rabdosia umbrosa var. latifolia 15:175 Isodomoic acid E3 17:21 Isodomoic acid G&H 26:479 Isodonjaponicus 24:273;29:101
439
Isodonal 15:142,150,159,162,172,173 13C-NMR of 15:159 from Rabdosiajaponica 15:172 from Rabdosia macrophylla 15:173 IH-NMR of 15:152 Isodonoiol 15:143,152,160,172 13C-NMR of 15:160 from Rabdosiajaponica 15:172 IH-NMR of 15:152 Isodopharicin A 15:115,122,129,174 13C-NMR of 15:129 from Rabdosia pharicus 15:174 ~H-NMR of 15:122 Isodopharicin I3 15:115,122,129,174 13C-NMR of 15:129 from Rabdosia pharicus 15:174 ~H-NMR of 15:122 Isodopharicin C 15:115,122,129,174 (+)-Isodrimenin 4:403-415,419 from Drimys species 4:404 from 1-abietic acid 4:405 from dpodocarpic acid 4:405 isomerisation from drimenin 4:407,408 synthesis of 4:405-415 Isodunnianol 20:271 Isodurene disulfonyl dichloride (DDS) 14:288 Isodysidenin 25:889 Isoeburnamine 14:635,636 synthesis of 14:635,636 (-)-Isoeburnamine 9:179 Isoekebergolactone B 2:273 Isoekerbergolactone 9:95 Isoelaeocarpicine 1:283 synthesis of 1:283 (+)-Isoelaeocarpine 12:277 Isoelectric focusing 2:19,347 Isoeleuterin 4:591 (+)-Isoepicampherenol 4:674 Isoepoxyteryxin 25:471 Isoeremolactone 15:210 synthesis of 8:425-428 (+)-Isoeremolactone 15:272,273 synthesis of 15:272,273 Isoeremophilone 15:243 Isoergosterol 18:509 Isoerivanin 7:232
Isoescin Ia (triterpene saponin) 29:575 effects on HIV- 1 protease 29:575 Isoetin 5'-glucoside 7:206,207,227 Isoeucommiol 7:472,473,475,485 6-epi-Isoeucommiol 7:473 Isoeugenol 5:473,497;21:595,607; 26:227 antibacterial activity of 26:226 Isoeuonyminol 18:747;23:663,674 Isoevoninic acid 23:674 Isofagaridine 27:159 6-methoxy adduct of 27:159 Isoflavan 4:388,389,391,392 Isoflavanones 27:893 Isoflavanquinone 24:221
Isoflavone synthase 25.655 Isoflavones 4:377,378,381-385,391-394; 17:19;22:314 ;23:742;27:484,745; 28:268,269,286,287 acetyldaidzein 28:269 acetylgenistin 28:269 aglycones 28:269 bioavailibity of 28:286 daidzein 28:269 genistein 28:269 glycosides 28:269 m green split peas 28:269 m miso 28:269 in plant foods 28:269 m soy foods 28:287 m soy cheese 28:269 m soy flour 28:269 in soy sauce 28:269 m soya bean 28:269 m soya milk 28:269 in textured soya protein 28:269 in tofu 28:269 in tofu yoghurt 28:269 Isoprenylated flavonoids 28:199,203, 244 chemistry of 28:244 kuwanon C as 28:245 kuwanon E as 28:245 kuwanon G as 28:245 kuwanon H as 28:245 kuwanon L as 28:245 morusin as 28:245 mulberrofuran A as 28:245
440
mulberrofuran G as 28:245 oestrogenic activity of 28:268 oxydihydromorusin as 28:245 synthesis of 4:377,378,381-385, 391-394;17:19 Isoflavonoids 7:193;22:459;27:841 Isoflustramine D 18:691 Isofraxidin 5:515,520;7:117,120,204, 224 anticancer activity of 5:521 sedative activity of 5:521 Isofraxidin drimenylether 27:593 28-Isofucosterol 20:234 Isofulvine 1:272,273 synthesis 1:272,273 Isofutoquinol 8:170 X-ray crystallography of 8:170 Isofutoquinol B 8:170 Isogemichalcone C 28:16 as aromatase inhibitor 28:16 Isogingerenone B 17:378 Isoglutamine 6:410 isomerisation of 6:410 rearrangement to glutamine 6:409-413 Isoglycyrol 28:224,228,241 anti-Helicobacter pylori activity of 28:241 anti-microbial activity of 28:224 biological activity of 28:228 (+)-Isogmelinol 26:200,241 as PAF-induced inhibitor 26:241 Isogmelinol 5:533 Isogmenolin 26:241 as PAF-induced inhibitor 26:241 Isoguanine 15:460 Isoguattouredigine 26:825,827 Isogyrrmochrome D 15:105-107 Isogymnomitrol 13:41 Isohanalpinone 23:814 Isoharziandione 21:234 Isohelenin 29:87 activity in EBV assay system 29:87 activity in iNOS, NFkB assay systems 29:87 activity in TPA, AA, PLA assay systems 29:91 Isohemandin 18:586
Isohemandion 18:552 from Heerandia ovigera 18:552 (-)-Isohopeaphenol 26:561 Isohoslundin 2:129,134 Isohumulen 27:574 Isohumulones 24:902-904 anti-hyperglycemic effects 24:902-904 Isoiguesterim 18:776 nor-Isoiguesterin 30:694 Isoiguesterine 30:665,667 structure of 30:665 Isoiguesterol 30:693-695 against drug-sensitive strain NF54 30:694 against multidrug-resistant strain K1 30:694 structure of 30:695 Isoimperatorin 9:402 Isoindoline 8:397-403 as a2 agonists 8:397-403 synthesis of 8:400-402 Isoindoline alpha-2 antagonists 8:400 Isoindolone 8:212,217 synthesis of 8:212;13:108-115; 142 Isoingenol 1:571I synthesis 12:234-245 Isointermediol " 9:473 (x-H-Isoipecosiue 26:973 Isoiridomymercin 16:289,20:68,69,74 Isojacareubin 30:620 from hypericum 30:620 Isojuliprosine 5:211 Isokaemferide 7:411-413 trans-Isokielcorin B 26:259 Isokomarovine 14:762 from Nitraria komarovii 14:762 from quinoline-5-carboxylic acid 14:763 synthesis of 14:763 via Bischler-Napieralski condensation 14:763 Isolactarane 17:154 Isolancerotriol 5:736 13C-NMR spectrum of 5:736 5-isovalerate of 5:736 Isolariciresinol 20:108,620;26:195,205 (+)-Isolariciresinol 26:268
441
Isolasalocid A 11:152 Isolaserpitine 5:725 Isolation 27:164-166 of chelilutine 27:156-166 Isolaulimalide 19:568 Isolaurenterol 25:787 Isolaurepinnacin 19:411 synthesis of 10:210,213 (2S,3S)-Isoleucine 10:277,278; 22:33,381 (2R,3S)-alloisoleucine from 10:277,278 Isolevoglucosenone 14:279 synthesis of 14:279 Isolexins 5:578 Isolichenan 5:309,310,322 Isolicoflavonol 28:17,224,243 anti-Helicobacter pylori activity of 28:243 anti-microbial activity of 28:224 as aromatase inhibitor 28:17 Isolimonen 20:13 (+)-trans-Isolimonene 29:83 activity in AM assay system 29:83 6-epi-Isolincosamine 11:446 Isoliquiretin 22:425 Isoliquiritigenin 22:425;28:228 biological activity of 28:228 Isoliquiritoside 22:424 Isoliquirtin 24:893-895 inhibitory effect in inflammation 24:893-895 Isoliquirtogenin 25:537,539 Isolobophytolide 8:15,19-32;10:10-13 antitumor activity 8:15,19-32 synthesis of 8:19-32 from Labophytum crassum 8:20 ~H-NMR spectrum of 8:20 X-ray analysis of 8:20 synthesis of 10:10-13 Isolongifolene 4:639 Isolongirabdiol 15:142 13C-NMR of 15:159 from Rabdosia longituba 15:172 tH-NMR of 15:151 Isolugrandoside 26:328,329 acetate of 26:329 Isomagellanol 18:746
Isomagnolin 26:201,241 Isomagnolol 26:227 Isomalabaricane triterpenes 21:254,273, 285 Isomaltase 499,504,505,38:7:57 Isomaltose 15:436 Isomaltoside 11:469-471 synthesis of 11:469-471 Isomarchantin C 2:283,284 (+)-Isomedicarpin 4:382,383 tuberostan from 4:382,383 synthesis of 4:382,383 Isomelodienone 9:400 Isomenthol 17:605;25:155 (+)-Isomenthol 21:585;29:83 activity in AM assay system 29:83 (+)-Isomenthone 21:585 Isomenthone 27:375 (-)-Isomenthone 29:83 activity in AM assay system 29:83 c~-Isomer 10:349 from enone 10:352 [3-Isomer 10:354 by 1,4-addition of thiolane anion 10:354 cis-Isomer 30:549 radical anions of 30:549 D-lyxo-Isomer 5:705,706 Isomerase 17:480 IDP-Isomerase 7:324 Isomerism 27:361 of monoterpenoids 27:361 Isomerization 1:189,413,414,447,448, 532;6:117,126,153-155,157,221, 541,542,556;10:410;16:236,371,615; 23:195 acid catalyzed 16:236 iodine catalysed 6:141 of carbon-carbon double bond 16:371 of cyclosterol 16:332 ofdiene 1:447,448 of glutamine 6:410 of isoglutamine 6:410 of N-cyclohexylisopropylamine (MMA) 1:532 of olefins 1:413,414
442
of azatidine acetates 23:195 photochemical 413,414 silylatropic 10:111 to catechol 16:615 with camphorsulfonic acid 6:222 with iodine/benzene 1:447,448 with methyl magnesium derivative 1:532 R,S Isomerization 6:141 cis-Isomerization 6:153,162 trans, cis-Isomerization 6:141,142 Isomerization process 27:350 kinetic characteristics of 27:350 Isomerization rates 27:350 of 8'-hydroxyabscisic acid 27:350 ofphaseic acid (PA) 27:350 Isomers 14:526-531 of 2-methyl-l,6-dioxaspiro [4.5] decane 14:526-531 synthesis of 14:526-531 Isomethuenine 5:126 Isomethuenine-N-oxide 5:126 (+)-Isomintlactone 19:153 preparation of 19:152 Isomitocins 13:445-467 mitomycins from 13:445-467 Isomitomycin A 13:434,445,446,453 from Streptomyces caespitosus 13:2 synthesis of 13:460-469 Isomitraphylline 25:25,26 Isomolvizarin 18:193 Isomucronulatol 7,2'-di-O-13-Dglucoside 27:499 Isomultiflorenol 7:164,165 Isomuramic acid 6:386 Isomycorhodin 2:140 DEPT spectra 2:142 hetero COSY spectra 2:142,143 sugar residue of 2:143 Isomyricanon 17:372 Isonaamidine 17:17 Isonaamine A 17:17,18 Ag'9-Isonakafuran-9 6:70 synthesis of 6:70 Isonakafuran-type sesquiterpenes 25:692 Isonaringin 26:744
Isoneriucoumaric acid 9:293-299 Isongaione acetate 15:237 Isoniazid 2:424 Isonicotinic acid hydrazide (INAH) 23:94 7-cis-Isonieratene 6:155,156 Isonimocinolide 9:297-299 Isonitramine 14:742-750 13C-NMR of 14:742 diastereoselectivity in 14:743-747 enantioselective synthesis of 14:743-747 from L-prolinol 14:743-747 from Nitaria sibricia 14:541 1H-NMR of 14:742 synthesis of 14:543 Isonitrarine (3-epinitrarine) 14:760 biosynthesis of 14:760 Isonitrile 12:411,414 aldol reaction of 12:411,414 2-amino alcohol by 12:411,414 with aldehyde 12:411,414 Isonitrile 17:14 Isonitrile reduction chemistry 12:211 (-)-Isonootkatone 16:239 Isonovaldal 25:152 Isonoyanine 20:265 Isoorientin (luteolin 6-C-glucoside) 29:579 effects on ACE 29:579 2-Iso-oxacephems 12:126 antibiotic activity of 12:126 Isooxazolidine-4-carboxylic acid 12:156 (-)-c~-Isoparteine 27:259 conformational studies of 27:258-259 Isoparvifolinone 5:800,801 formation from parvifoline 5:800,801 ozonolysis 5:800,801 (+)-Isopeduncularine 11:284,285 13C-NMR of 11:285 synthesis of 11:284,285 Isopelletierine 12:284 Isopenicillin 11:211 Isopenicillin-N-synthase 11:212,213 Isopentalenene 3:6,61
443 Isopentaquine 22:150 Isopentenol 7:104;8:70 Isopententenyl diphosphate 11:219-222 farnesyl diphosphate from 11:219-222 formation of 11:219-222 from mevalonate 5-diphosphate 11:219-222 geranyl diphosphate from 11:219-222 Isopentenyl diphosphate 7:322-324,330, 348,352 Isopentenyl pyrophosphate 21:721; 22:255 Isopentenyl tRNA 22:255 Isopentenyl-diphosphate: dimethylallyl diphosphate isomerase 11:201 from Saccharomyces cerevisae 11:201 Isopentyl diphosphate (IPP) 25:130 2-Isopentyl-3-(E-4-methylpent- 1-enyl)5-methyl-pyrazine 5:265,266 Isoperoxisomicines 22:568,582,593, 594,596 Isopetasin 29:87 activity in 5LOX, PLA assay systems 29:87 Isophorone 26:297,298,307 microbial transformation of 26:307 Isophysodic acid 20:283 Isophytolaccagenin 7:144,145 Isophytolaccinic acid A 7:144,145 Isopicropodophyllone 5:481,483;26:193 Isopicrostegane 26:196 ent-Isopimar- 15-en-6a, 7 c~,8c~-triol 15:170 13C-NMR of 15:170 from Rabdosia parvifolia 15:173 IH-NMR of 15:169 ent-Isopimarane 15:112 Isopimaric acid 20:690 from Salvia candidissima 20:690 from Salvia heldrichiana 20:690 from Salvia wiedemanni 20:690 Isopimpinellin 22:522,539;23:352 Isopinocampheyl borane 13:71 Isopiperitenol 25:150
(+)-Iso-plumericin 16:301 synthesis of 16:301 L-Isopodophyllotoxone 18:600 Isopregnomisin 23:773;26:249 Isoprene 4:394 chromanes from 4:391,396,398 (Z)-Isoprene 8:65 Isoprene intermediate 22:379 Isoprene-rule diterpenes 11:4 Isoprenoid biosynthesis 17:471 Isoprenoid metabolites 11:219-222 Isoprenoid pathway 21:276 metabolites derived from 21:276 Isoprenoid quinones 30:304 in arthropods 30:304 in sea lichens 30:304 Isoprenoid unit 25:513 Isoprenoids 6:133,185;16:662-670 synthesis of 16:662-670 Isoprenyl- 1,4-naphthoquinones 29:735 biosynthesis of 29:735 Isoprenylated flavonoids 28:199,203, 207,244 biological activity of 28:199 effect on testosterone 5~reductase 28:244 from medicinal plants 28:199 hypotensive action of 28:207 Isoprenylation 11:200 by 4-(y,y-dimethylallyl) tryptophan synthase 11:200 of tryptophan 11:200 Isoprenylphenols 17:451,20:271 biosynthesis of 17:747 Isopristimerin III 7:149,760 2-Isopropenylnaphtho [2,3-b] furan-4,9dione 20:494 Isopropyl 1-thio-[3-D-galactopyranoside 8:315 13-Isopropyl pimelic acid 25:154 8-Isopropyl-2,5-dimethyl- 1,4-naphthoquinone 14:319 5-Isopropyl-3,7-dimethyl- 1H-inden- 1one 14:328,329 5-Isopropyl-3,7-dimethyl- 1-oxo- 1Hindene-6-carbaldehyde 14:319 7-Isopropyl-4-methyl- 1-azulenecarbaldehyde 14:319
444 3-I sopropyl- 8-(3,7- diisopropyl- 1azulenyl) benzofulvene 14:340 Isopropylcatechol 14:684-686 taxodione from 14:684-686 (R)-2,3-Isopropyliden 12:21,22 glyceraldehyde 12:21,22 O-Isopropylidene 6:269,270 protection with 6:269,270 5,6-O-Isopropylidene 1,2-(methoxycarbonyl)ethylidene-ot-Dgalactofuranose 14:233 1,2-O-Isopropylidene derivative 6:279,280,285,286 from D-xylose 6:269,270 from L-xylose 6:269,270 (R)-2,3-Isopropylidene glyceraldehyde 18:181 D-Isopropylidene glycerldehyde 19:166
1,2-O-Isopropylidene-(-)-swainsonine
12:317 2,3-O-Isopropylidene-l,6-di-O-ptoluenesulfonyl-c~-L-sorbofuranose 10:528 4,5, O-I sopropylidene-2-methylpent-2ene- 1,4,5-triol 10:436,437 Claisen rearrangement of 10:436,437 with triethyl orthoacetate 10:436,437 2,3-O-Isopropylidene-D-erythrose 12:318 1,2:5,6-Di- O-Isopropylidene-D-glucose 12:41 vinyl iodide from 12:41 1,2-O-Isopropylidene-D-glyceraldehyde (1,3-dioxolane) 10:437,438 Isopropylidene-D-glyceraldehyde 30:469 addition of 30:469 2,3-O-Isopropylidene-D-glyceraldehyde 6:353 2,3:5,6-di-O-Isopropylidene-D-mannose 30:452 nucleophilic acylation of 30:452 2,3-O-Isopropylidene-L-erythrose 12:330,331 (-)-8-epi-swainsonine from 12:330,331 (-)-8a-epi-swainsonine from
12:330,331
(-)-8,8a-di-epi-swainsonine from
12:330,331 Isopropylidene-L-threitol 19:1672,31,8-O-Isopropylidenylcastanospermine 12:345 (-)-Isoprosopinine 12:435 (-)-Isoprosopinine A 12:475 Isoprostane F2a 25:596 Isoproterenol 25:594,896 Isoprotostemonine 21:770 Isoptaquiloside 26:719,722 Isoptera 19:118;22:371 (+)-Isopteropodine 13:490,491 Isopteryxin 25:471,476 (-)-Isopulegol 16:268 Isopulegol 25:136 (-)-Isopulegole 21:585 Isopulmericin 16:299 antifungal activity of 16:299 antileukemic activity of 16:299 cytotoxic activity of 16:299 3,4-O-Isopyrilidene-3,3,4,5'-tetrahydroxy-stilbene 22:626 Isopyrilidene-derivative 22:626 Isopyrum thalictroides 29:578 Isoquercitin 7:227;22:645;29:573,579 effects on ACE 29:579 effects on HIV-1 protease 29:573 Isoquinoline 10:185,673,674;25:4,542, 824,825 ;30:563-567,588 against cancer cell lines 30:588 based PKA inhibitor 25:542 from genus Hernandia 30:563-567 Isoquinoline alkaloids 1:168;5:3,42, 494,265,266;13:642;21:107,733; 27:819,863;30:560,562,588,590,594, 597 (-)-salsolinol 25:531 (+)-corytuberine 30:589 (+)-hemovine 30:589 (+)-laurotetanine 30:589 (+)-magnoflorme 30:589 (+)-N-formyldehydroovigerine 30:589 (+)-N-formylnomantenine 30:589
445
(+)-N- formylovigerine 30:589 (+)-N-hydroxyhemangerine 30:589 (+)-N-methylhernangerine 30:590 (+)-ovigerine 30:590 7-formyldehydrohernangerine 30:589 7- formyldehydroovigerine 30:589 7-hydroxy-6-methoxy- 1methylisoquinoline 30:589 7-oxohernagine 30:590 against cancer cell lines 30:588 annelated benzazecines from 6:483 antiplatelet aggregation activity of 30:560 atherosperminine 25:540 cytotoxicity of 30:560 benzoxanecines from 6:483 demethylsonodione 30:589 dihydropyranocoumarins 25:540 dopamine 25:531 Epstein-Barr virus inhibition due 30:560 hernandonine 30:589 hernanymphine 30:589 Isoquinoline derivatives 6:495,496 Isovanillin 30:567,594 methano-bridged benzoxaxecines from 6:483 narceine 25:533 N-hydroxyovigerine 30:589 N-methylcorydaldine 30:589 N-methylovigerine 30:590 phenylpropanoid glycosides 25:540 synthesis of 1:187-226 thalifoline 30:590 Isoquinoline N-oxides 6:468 pyrolysis of 6:468 Isoquinoline-derived alkaloids synthesis of 6:467-502 Isoquinolinequinones 10:77-145 ;21:265 as antibiotics 10:77-145 from actinomycetes 10:77-145 from marine sponges 10:77-145 naphthyridinomycin type
10:77,103-115 saframycin type 10:77-103 synthesis of 10:77-145 Isoquinolines 17:91 Isoquinolines synthesis of 1:168 Isoquinolinium betaine 1:189 Isoquinolinium salt 14:503 cycloaddition of 14:503 with chiral dienophiles 14:503 Isoquinolino-pyrrolinedione 3:465,466 photochemical reaction of 3:465, 466 Isoquinuclidine 1:112 (+)-3-Isorauniticin 16:437 synthesis of 16:437 Isorauniticine 9:171 3Isorenieracistene 6:155,156 Isoreserpic acid lactone 25:24 conformation 25:24 Isoreserpiline 1:158;5:128 conversiont to bleckerine 1:158 Isoreserpine 13:410;25:3,13,29 conformation 25:23 Isoretronecanol 1:231,233,235-237,241, 244,247-251,253,256,257,259,260, 325,326,339 (+)-Isoretronecanol 13:483,484 synthesis of 13:483,484 Isoretronecanol 3:54;14:737 from dihydrofuran 14:737 synthesis of 14:737 Isoretronecanolate 1:248 synthesis of 1:248 Isoretronecic acid 1:265,266 synthesis of 1:265,266 Isoretulinal 1:36 Isoretuline 1:38,39 Isorhamnetin 5:652;7:206,227;29:577 effects on N-aminopeptidase 29:577 [3-Isorhodomycinone 4:318 by C-prenylation 4:382,384 from desoxybenzoin 4:383,384 Isorhodoptilometrin-2'-sulfate 28:718 Isorhynchophylline 25:26 Isoriccardin C 2:283,284 Isoridentin 7:230 (-)-Isoroemerialinone 2:257 Isorugosin D 23:405,408
446
Isorugosin E 23:405,408 Isoryanodol-type diterpenes 26:852 insecticidal effects of 26:852, 1136 Isosabandin 7:225 Isosaccharinolactone Isosacculatal 2:278,279 Z-Isosafrol 8:161 Isosakuranetin 7:228;23:747;26:744 Isosalutaridine 18:58 Isosandwichine 9:183,185 Isosarmentosin 21:738,740 Isoschaftoside 7:227 Isoschumanniophytine 21:145 Isoscopoletin 5:515,516;26:315,332, 333,334,342 Isoscopoletin-13-D-glucoside 5:515,516 Isoscutellarein 5:624,627,658 Isoscutellarein-4'-methyl ether 7glycosides 5:658 Isosegoline A 23:276 Isoshinanolone 2:213,215,216,222,225, 227,228;5:754,755 biosynthesis of 2:227,228 CD curve of 2:226,227 chemical interconversion of 2:222,223 configuration of 2:224 ~H-NMR spectrum of 2:227 oxidation with DDQ 2:227 physical data of isomers 2:225 stereoisomers of 2:222 structure and stereochemistry 2:222-225 UV spectra of 2:226 epi-Isoshinanolone 2:213,215,216, 222-224 neo-Isoshinanolone 2:222,224 Isosilymarin 5:496 Isosinensetin 23:747 Isositsirikine 2:375,125;9:168 16-epi-Isositsirikine 5:125 E-Isositsirikine 9:171 Z-Isositsirikine 9:171 Isosolenopsin A 1:389,390 synthesis of 1:389,390 (+)-Isosophoramine 18:323
(+)-~-Isosparteine 27:259 conformational studies of 27:258-259 Isospiciformin 27:568 5-epi-Isospongiaquinone 15:315,318 Isospongiaquinone 15:315,418 Isostatine 10:263,266-269,272-275, 278-284 (3S,4R,5S)-Isostatine 12:476,477 (-)-Isostegane 29:389 steganes synthesis of 29:389 Isostemotinine 21:759,762 Isosterism 13:165 Iso-steviol activity 29:100,101 Isostigamasterol 18:515 Isostrychinine 26:1051,1052 Isostrychnine-N-oxide 26:1051 Isoswertianoline 22:533,541 Isoswinholide A 26:1197,1198,1229 paterson's synthesis of 26:1229 Isotaxiresinol 20:108 Isotaxiresinol-6-methyl ether 20:107 Isotelekin 7:233 Isotenulin 20:10 Isotetracenone antibiotics 5:596,597 (+)-Isothebaine 16:512 Isothiocyanate 17:14;21:329-331,346, 349-367;25:514;28:658 as terpenes 28:658 as precursor of formamido group 28:658 in nudibranchs 21:358 (+)- 10-Isothiocyanato-4,6-amorphadiene 25:852 7-Isothiocyanato-7,8-dihydro- abisabolene 25:848 (+)-4-Isothiocyanato-9-amporphene 25:852 (+)-l-Isothiocyanatoaromadendrene 25:853 10-Isothiocyanatobiflora-4.15 diene 25:854,856 (+)-Isothiocyanatocubebane 25:853 (-)- 10-Isothiocyanatoguaia-6-ene 25:852 (-)- 10-Isothiocyanatokalihiniol G 25:856
(-)- 15-Isothiocyanato-l-epi-kalihinene 25:856
447
Isothiocyanato-N-(4-nitrophenyl) benzeneamine (amoscanate) 26:481 (+)-5-Isothiocyanatopapukeanane 25:853 2-Isothiocyanatopupukeanane 21:346, 349 (-)-9-Isothiocyanatopupukeanane 21:354 5-Isothiocyanatopupukeanane 21:365 (+)-6a-Isothiocyano-5aH,7aH, 10aendesm-4-(14) ene 25:852 (-)- 11-Isothiocyano-7-flH-endesm-5ene 25:852 (+)- 10R-Isothiocyanoalloaromadendrane 25:853 (-)- 10a-Isothiocyanoalloaromadendrane 25:853 2-Isothiocyanotopupukeanane 21:356 9-Isothiocyanotopupukeanane 21:356 (+)-(1R, 6S, 7S, 1OR)-10-Isothiocynato-4amorphene 25:852 (-)-(IS, 6R, 7R, 10R)- 10-Isothiocynato-4amorphene 25:852 2-Isothiocynoto-6-axene 25:850 Isothiouronium salts 8:316 (-)-4a-Isothioyanatogorgon-11 -ene 25:852 (-)-3-Isothuj one 27:384 Isothujone 7:95,98,99,101 Isotingenone 18:760 Isotingenone III 18:760 (-)-Isotirucallol 16:211 biomimetic synthesis of 16:211 Isotissoclinotoxin A 25:833,834 Isotope effect 9:96,102-106,475,476; 27:348 Isotope pattern 2:43,44 Isotope shifts 9:106 Isotopic analysis 13:334-337 Isotopic distribution 2:2,25 lsotricha 2:294 Isotrichodiol 13:524 Isotriptophenolide 23:685 Isotussilagin 1:230,231 synthesis of 1:230,231 Isovaleraldehyde 4:396,398 5-Isovalerate 5:725,727 of ferutriol 5:725,727
of isolancerotriol 5:725,727 of lapiferol 5:725 Isovalerate 5:735 13C-NMR spectrum of 5:735 of erpoxyisolancerotetrol 5:725,727 of epoxyjaesehkeanandiol 5:735 of isolancerotetrol 5:725,727 6[3-Isovaleroxylabda-8,13-dien-7c~, 15diol 17:27 Isovallesiachotamine 5:125 Isovangustin 7:233 Isovanihuperzine A 21:747 Isovanillin 30:567,594 as platelet aggregation inhibitor 30:594 Isovanilline 21:747 Isovelbanamine 14:866-867 from 1-glutamic acid 14:866-867 synthesis of 14:865-867 via thio Claisen rearrangement 14:865-867 Isovelleral 26:461 Isovincadifformine 14:850-853 synthesis of 14:850-853 Isovincoside (strictosidine) 6:520 Isovitexin (apigenin 6-C-glucoside) 7:227;29:579 effects on ACE 29:579 Isovoacangine 5:127;9:174 7S-Isovoacristine 5:128 Isowildordic acid 23:674 17-Isowithanolide 20:246 Iso-Withasomine 1:343 synthesis of 1:343 Isoxaben 26:370 Isoxanthochymol 22:659 Isoxazolidine 1:230,231 ;19:42 synthesis of 1:230,231 [3-aminoalcohol from 12:290 hydrogenation of 12:290 Isoxazolines 12:20-22 Isoxazopodophyllic acid 26:214,215 Isoyangambin 26:242 as PAF-induced inhibitor 26:242 Isozeylanone 2:212 Isozonarol 6:17 from Dictyopteris undulata 6:17 Rau synthesis of 6:17
448 synthesis of 6:17,18 Welch synthesis of 6:17 Isozonarone 15:297 Isozymes 17:481 ;30:827,828,843,826, 829 F-I as 30:826 F-I-0 as 30:826 F-I-2 as 30:826 F-II as 30:826 F-I-I as 30:826 F-II as 30:843 F-Ill as 30:826 F-III-1 as 30:826,843 F-III-2 as 30:826,843 from Phaseolus vulgaris 9:563 immunological analyses of 30:829 Iso-[3-peltatin B methyl ether 18:59 ISP 21:555 Istanbuline D 20:660 from Salvia yosgadensis 20:660 ltersonilia tilletiopsis 5:291 Itocyclization 10:6 Itodulosides I-V 27:41,45,46,47 structures of 27:46,47 Itraconazole 22:60 Iva xanthifolia 5:728 (+)-Ivalin 10:405,406 Ivermectin 12:8,9;26:441,447,453,457, 468;28:396 as macrolide antibiotic 28:396 biological activity of 12:8,9 Ivy PNP 25:383 Ixocarpalactone 20:241,242 Ixocarpalactone A 20:185,194,223 Ixocarpalactone B 20:181,194 Ixodes ricinus 26:695
(+)-Jaborol 20:181 Jaborosa bergii 20:180 Jaborosalactone A 20:234 Jaborosalactone F 20:223,20:242 Jaborosalactone M 20:181 Jacaranda acutifolia 5:682 Jacaranone 16:616 Jaceidin 7:227 Jaceosidin 7:227 Jaceosidin-7-sulphate 5:655
Jaceosidine-7,4'-disulphate 5:655 Jadiffine 9:172 Jaeschferin 5:722,725 Jaeschkeanadiol 5:722,723,730-332 JAK/STAT- linked receptors 25:520 JAK/STAT pathway 25:519 Janolus cristatus 28:146 Janolusimide 28:146 from Janolus cristatus 28:146 neurotoxic lipophilic activity of 28:146 Janua bioticus 17:100 Japonenyne A and B 25:802 Jarsin (L1 160) 22:693,694-700 Jasmin flowers 19:158 Jasmin-flower oil 6:557 Jasminin 7:443 Jasminum grandiflorum 19:152, 158-159;29:581 Jasminum officinale 7:218,222,223 Jasminum sp. 7:218,219 Jasmolin I 27:588 Jasmolin II 27:588 Jasmonates 25:367,373 Jasmone 9:534,536 cisJasmonic acid 6:557;25:374;27:64, 71-73 biological activities of 27:72,73 generation of 27:71,72 Jasonia candicans 21:599 Jasonia montana 21:599 Jaspamide 5:429;25:757,768;26:485 anthelmintic activity of 5:429 antifungal activity of 5:428 derivative 25:768 insecticidal activity of 5:428 Jaspis 5:428;19:580;613;21:273; 25:700,714 ;26:485,488,1210;28:697 Jaspis coriaceae 25:725 Jaspis splendans 25:768 Jaspis sponges 21:252 jaspamide from 21:252 Jaspisamides 25:727 Jaspisin 28:697 sea urchin hatching inhibition by 28:697 Jasplakinolide 26:485 Jaspsamide A 25:727 Jasus lalandii 29:10
449 Jatamansone 22:527,540 Jatorrhizine 11:201-204 by Berberis cell cultures 11:201-204 formation of 11:201-204 from columbamine 11:201-204 Jatrihizine 21:733 Jatrogrossidione 26:809,811 Jatropha curcas L. 22:524 for convulsions and fits 22:524 Jatropha gossypifolia L. 10:152;22:524 as anticonvulsant 22:524 Jatropha grossidentata 26:809,810 Jatropha isabelli 26:810 Jatropha multifida L. 22:524 as anticonvulsant 22:524 Jatrophane 2:262 Jatrophone 10:152,155,156;26:809 Jatrorrhiza palmata 27:749 Jatrorrhizine 21:84 4,4'-bis-Jatrorrhizine (v) 27:749 and electron transfer 27:749 Jauch 29:127 sesquiterpenoids drimane-type synthesis by 29:127 Jaundice 22:643 JB6 cell line 30:593 tumor-promotion in 30:593 JB6 cell line transformation 30:592 inhibition of 30:592 Jegosapogenol 21-(2,3-dihydroxy-2methyl)-butanoate)-22-angelate 7:139,141 Jeiranbatanolide 7:235 Jeitacin A&B 26:442 Jenisseensoside C 26:47,55 granulocyte phagocytosis of 26:47,55 Jenisseensoside D 26:47,55 granulocyte phagocytosis of 26:47,55 Jenisseensosides A-D 26:46 cyclooxygenase inhibitory activity of 26:46 Jenkins's synthesis 12:185,186 Jereicopsis 26:1175 Jereicopsis graphidiophora 26:1206, 1207,1214 Jereisterol B 26:1206,1207
Jerumanis method 21:511 metal complexing assays 21:511 (+)-Jerusalemine 29:377 allocolchicinoids total synthesis of 29:377 Jerveratrum group 23:563 Jervine 7:16,17,21,22;21:97;23:563, 565,575 Jessie acid 25:182 Jessie acid arabinoside 25:182 Jessie acid xyloside 25:182 Jeunicin 17:22 JICST-E 19:758 Jinbricatime 25:824 Jinyinhouside A 21:656 Jiuhuanin A 15:130 13C-NMR of 15:155 from Rabdosia macrocalyx var. jiuhua 15:173 lH-NMR of 15:146 Johnson synthesis 14:681-684 oftaxodione 14:681-684 Johnson-Claisen rearrangement 10:428-438 ofallylic alcohols 10:428-438 of aldoheptofuranoses 10:432-436 of D-glyceraldehyde derived allylic alcohols 10:436,437 of 4-(3-hydroxy- 1-propenyl) derivatives 10:436-438 of L-lyxofuranose derivatives 10:431,432 Johnson-Lemieux reaction 3:328 Jones map 17:539 of amino acid residues 17:539 Jones model 17:507 Jones oxidation 4:50,456,465,470, 490-492;16:29,30,72,323,248,235, 514,595,627,641,551,558;19:252, 304,320-321 ;21:715 ;22:277 ;26:1209, 1225 Jones reagent 6:17,25,55,78,509,515, 461 ;12:466,508,613; 14:818;19:173, 428 reaction with stypodiol methyl ether 6:55 Jorunna funebris 21:265 Jospis sp. 25:704,719,727,731
450
Jotismati 23:654 Joullie method 10:283 Jourdan-Ullman condensation 13:353-355 Ju-Fang synthesis 6:14 of (+)-polygodial 6:14 of (-)-polygodial 6:14 of (• 6:14 Juglans 26:905 Juglans mandshurica 26:899 Juglans regia 21:503;23:342;28:424 Juglone 9:258;26:363,370,470,638, 868;30:313 structure of 30:313 Juglone derivative 4:396,398 synthesis of 4:396,398 Jujubasaponins II-VI 27:42,48-50 structures of 27:49,50 Jujuboside B 27:41,42,45,46 structure of 27:46 Julandine 1:363 synthesis of 1:365,367 Julia coupling 1:457,458,461-464 Julia olefination 16:230;21:397 ;26:1219 Julia reaction 1:454,456 Julia sulfone 1:463 Julia synthesis 9:356 of 22,23-dihydroavermectin B ~b 12:17-19 Julibroside I 25:208 Julibroside II 25:208 Julibroside III 25:208 Julichrome Q1 20:277 Julifirosine 5:211 Julifloridine 5:211 ;9:70 Juliflorine 5:211 Juliflorinine 5:211 Juliprosine 9:72 Juliprosinene 9:71,72,77 Juliprosopine 9:70 Jungermannia infusca 2:280 Jungermanniaceae 25:252 Juniper communis 21:616 Juniperus 27:372 (+)-limonene in 27:372 Juniperus communis 5:485;20:16 Juniperus foetidissma 8:163 8,14-cedranoxide from 8:163 Juniperus macropoda. 22:524
Juniperus occidenatalis 28:408 Juniperus procera 25:257,259 Juniperus sabina 20:16;26:214 Juniperus virginiana 15:346;20:16; 28:408 Junosidine 13:348,349 from Citrusjunos 13:348,349 Junosine 13:348,349 from Citrusjunos 13:348,349 Juriperus communis 27:370,372 essential oils from 27:370 Jusiaea decurrens 9:214 Justicia procumbens 17:333;26:226, 235,243,265 justicidin B from 26:243 justicidin E from 26:243 neojusticin A from 26:243 taiwanin E from 26:243 taiwanin E methyl ether from 26:243 diphyllin apioside-5-acetate from 26:226 diphyllin asioside from 26:226 diphyllin from 26:226 justicidin A&B from 26:226 Justicia procumbens var. leucantha 26:226 diphyllin apioside-5-acetate from 26:226 diphyllin asioside from 26:226 diphyllin from 26:226 justicidin A&B from 26:226 Justicia prostata 17:335 Justicidin B 26:243 as PAF-induced inhibitor 26:243 Justicidin D (neojusticin A) 26:194 Justicidin E 26:243,265 as PAF-induced inhibitor 26:243 (+)-Juvabione 16:211 synthesis of 16:211 Juvabione 22:383;25:546 Juvenile hormone (JHI) 1:704-707 synthesis of 1:704-707 Juvenile hormone III 1:704,705;22:369, 370,371 from Coleoptera 22:371 from Dictyoptera 22:371 from Hymenoptera 22:371 from lsoptesa 22:371
451 from Lepidoptera 22:371 from Orthoptera 22:371 synthesis of 1:704,705 Juvenoid activity 22:384 Juvenoid effects 22:386 ofjuvabione 22:386 Juvenoids 22:383,395 Juvocimene I 22:392 Juvocimene II 22:354,392,395 K + channels 25:530-531,534 K+-channel mediated ion transport 25:497 K-252a ("SF-2370") 12:366,368 K-252b 12:384 from Nocardiopsis sp. K-290 12:366,368 protein kinase C inhibitor of 12:384 K-252c (staurosporinone) 12:366,368, 369 from Nocardiopsis sp. K-290 12:366,368,369 protein kinase inhibitor of 12:386 synthesis of 12:379-381 K-252d 12:366,368,369,386 Nocardiopsis sp. K-290 12:366, 368 protein kinase inhibitor of 12:386 K-25a 12:366,368,369,384,390,395, 396,398,399 anihypertensive activity of 12:398 antaillergic effect of 12:398 antiinflammatory effect of 12:398 antitumor activity of 12:395 effect on nerve growth factor 12:396 porcine spleen protein kinases inhibitor of 12:390 prostaglandin production by 12:399 protein kinase A inhibitor of 12:384 protein kinase C inhibitor of
12:384,390 protein kinase G inhibitor of 12:384 K562 cells study 27:877 KA-antibiotcs 4:434 in carbapenem 4:434 Kabalka's procedure 6:547,548 Kadsura heterocollita 26:240,249,259 burchellin from 26:249 gomisin M from 26:240 heteroclitin F from 26:259 heterociitin G from 26:259 kadsurenone from 26:249 Kadsura interior 26:223 gomisin-G from 26:223 interiotherin A from 26:223 schisantherin D from 26:223 Kadsura sp. 17:346 Kadsuranin 26:197,224 Kadsurenin H 26:240 as PAF-induced inhibitor 26:240 Kadsurenone 16:561 ;26:240,241,249 as PAF-induced inhibitor 26:240 Kadsurujaponica 26:255 Kaemferol 30:224 from natural flavonol 30:224 Kaempferia 23:840 Kaempferia galanga 23:840;24:273 Kaempferol 7:206,227;22:317,615, 661 ;25:541,544,546,594,615;26:747, 748,750,763,764,769;29:573 effects on HIV- 1 protease 29:573 Kaempferol-3,7,4'-trimethyl ether 23:797 Kaempferol 3-glucoside 23:761 Kaempferol 3-methyl ether 20:712 from Salvia yosgadenis 20:712 Kaempferol 3-O-(2"-f3-D- xylopyranosyl)-cz-L- rhamnopyranoside 28:64, 65 anti-oxidant activity of 28:64,65 Kaempferol 3-O-(6"-O-rhamnopyranosyl)galactopyranoside 7-0glucopyranoside 5:633 Kaempferol 3-O-a-L-rhamnopyranoside 28:64 Kaempferol 3-rutinoside 23:747
452 Kaempferol-3-O-(2"- O-galloyl)glucoside 29:579 effects on ACE 29:579 Kagan' s ether 30:215 cyclisation of 30:215 mechanism of formation of 30:215 Kahweol 29:101 activity in skin-6 bioassay system 29:101 activity in CYP bioassay system 29:101 activity in GSH bioassay system 29:101 activity in GST bioassay system 29:101 Kaikasaponin I 25:111,112,115,116,118 Kaikasaponin III 25:95,99,104,115,116, 118 allo-Kainic acid 1:328,329,334,335 synthesis of 1:328,329,334,335 Kainic acid 12:446;21:70,302;25:529 (-)-ct-Kainic acid 26:478 Kainic acid-binding glutamate receptors 25:529 Kainoids 21:302 Kairomones 8:219;22:95 Kakkasaponin I 25:95,104 Kakkasaponin III 25:111,112 Kala-azar 2:302 Kalafungin 4:591,617,618,128 Kalecide 21:381 Kalihinane diterpenes 26:810 cycloamphilectanes 26:810 7,20-diisocanoisocycloamphilec tane 26:810 epiamphilecladienc 26:810 7-isocyano- 11 (20), 14,7isocyano-cyclo-amphilect-10ene 26:810 isocycloamphilectanes 26:810 Kalihinane diterpenoids 25:689 Kalihinanes terpenoids 27:877 Kalihinenes X,Y and Z 21:366 (+)-Kalihinol 25:856 Kalihinol A 21:331,366;25:757; 26:466,810,812 Kalihinol E 21:331,366 Kalihinol-F 21:331.351
Kalihinols 25:854 (-)-Kalilinol G 25:856 Kalinanes 25:782 (-)-Kalinihol 25:856 Kalinihol I 25:856 Kalinihol J 25:856 Kalipyran B 25:783 Kalization 24:194 Kallilolides 23:180 Kalopanax pictus 30:203 use in folk medicine 30:203 use in rheumatoid arthritis 30:203 Kalopanax pictus 30:203 use in rheumatoid arthritis 30:203 Kalopanax saponins 15:191 Kalopanaxsaponins-A 30:203 antinociceptive effect of 30:204 Kalopanaxsaponins-I 30:203 antinociceptive effect of 30:204 kappa-opioid receptor 30:205 activation by (+)-allomatrine 30:205 activation by (+)-matrine 30:205 kappa-opioid receptor activation 30:207 by menthol 30:207 Kamebacetal A 15:135,137;29:101 activity in NFkB bioassay system 29:101 activity in NO bioassay system 29:101 from Rabdosia excisa 15:171 from Rabdosia henryi 15:172 from Rabdosia latifolia var. reniformis 15:172 from Rabdosia umbrosa var. leucantha 15:175 IH-NMR of 15:145 Kamebacetal B 15:137 from Rabdosia umbrosa var. leucantha 15:175 IH-NMR of 15:148 Kamebakaurin 15:117,125,131,175; 29:101 activity in NFkB bioassay system 29:101 activity in NO bioassay system
453 29:101
~3C-NMR of 15:131 IH-NMR of 15:125 from Rabdosia excisa 15:171 from Rabdosia henryi 15:172 from Rabdosia inflexa 15:172 from Rabdosia longituba 15:173 from Rabdosia serra 15:174 from Rabdosia umbrosa 15:175 from Rabdosia umbrosa var. leucantha 15:175 Kamebanin 15:171;29:101 activity in NFkB bioassay system 29:101 activity in NO bioassay system 29:101 from Rabdosia excisa 15:171 from Rabdosia inflexa 15:172 from Rabdosia umbrosa 15:175 from Rabdosia umbrosa var. hakusanensis 15:175 from Rabdosia umbrosa var. latifolia 15:175 from Rabdosia umbrosa var. leucantha 15:175 Kameda 29:481 validamine synthesis by 29:481 Kampanols 24:449-450 biological activity of 24:450 structures of 24:449 Kampo medicines 24:875-926 active compounds of 24:878 anti-angiogenesis action of 24:875-925 anti-hyperglycemic action of 24:875-925 anti-inflammation action of 24:875-925 anti-proliferation action of 24:875-925 blood glucose regulatory action of 24:875-925 blood vessel contraction of 24:875-925 blood vessel relaxation of 24:875-925 chemical-structure-activity of 24:875-925 neuromuscular blocking action of
24:875-925 pharmacological activity of 24:875-926 smooth muscle contraction of 24:875-925 smooth muscle relaxation of 24:875-925 Kanamycins 14:144;20:714 Kanedelia candel 7:180,181,183,184, 194,195 Kanerin 9:293,294 Kanerodione 9:293,294 Kanerol 9:293 Kaneroside 9:293,294 Kanglemycin 23:54 Kanglemycin A 23:59 Kansuinine B 2:262,264,266 Kanzonol B 28:229 biological activity of 28:229 Kanzonol G 28:229 biological activity of 28:229 Kanzonol H 28:229 biological activity of 28:229 Kanzonol P 28:229 biological activity of 28:229 Kanzonol R 28:229 biological activity of 28:229 Kanzonol S 28:229 biological activity of 28:229 Kanzonol U 28:229 biological activity of 28:229 Kanzonol V 28:229 biological activity of 28:229 Kanzonol W 28:229 biological activity of 28:229 Kanzonol X 28:229 biological activity of 28:229 Kanzonol Y 28:229 biological activity of 28:229 Kaposis sarcoma 2:421 Kappa receptors 22:24 Kappa-carrageenan 26:1148 Karachicine 2:180,181 Karacoline 25:528 Karakin 27:522 Karamatsu 20:613 Karamatsuic acid methyl ester 29:99 activity in EBV assay system 29:99
454
Karatavic acid 1:660,662 from Ferula karatavika 1:660 synthesis of 1:660-662 cis-Karenin 9:295,296 trans-Karenin 9:295,296 Karounidiol 25:61 Karpluspople expression 17:552 Karvi 23:652 Karviskione 20:277 Karwinskii 22:555,583,585,586,589, 591-592,600 Karwinskii calderonii 22:556,560,589 Karwinskii humboldtiana 22:556,558, 559,563,570,572,577,583,585-590, 600 Karwinskiijohnstonii 22:556,559,572, 578,585,589 Karwinskii latifolia 22:556,583,589 Karwinskii mollis 22:556,559,572,589 Karwinskii parvifolia 22:56,559,562, 563,567,573,577,583,588,589,592, 593,596,600 Karwinskii rzedowskii 22:556,559,589 Karwinskii subcordata 22:556,559,572, 589 Karwinskii tehuacana 22:556,559,570, 571,589 Karwinskii umbellate 22:556,559,570, 572,588 Karwinskii venturae 22:556,559,589 Kassinin (KAS) 27:800 Kasugamycin 23:343 (-)-Katihinol L 25:856 Kato's synthesis 12:181,182 of seco-taxane 12:181,182 KATpchannels 25:534 Katsuki-Sharpless epoxidation 12:324, 481 Kauniolide 7:235 ent-Kaur- 16-en- 19-oic acid 29:100 activity in NFkB bioassay system 29:100 activity in EBV bioassay system 29:100 (-)-Kaur-16-en-19-oic acid 9:396,397 ent-Kaur-16a-ol-19-oic acid 26:811 ent-Kauran-1613,17-diol 15:172 from Rabdosia glutinosa 15:172 ent-Kauran- 16-en- 19-oic acid 26:811
8,9-seco-ent-Kaurane 15:162 (-)-Kaurane 19:387 ent-Kaurenic acid 30:713 structure of 30:713 Kaurane 9:271;25:241,246 6,7-seco-ent-Kaurane skeleton 15:136, 162 Kaurane skeleton 19:387 6,7-seco-ent-Kauranes 15:112 Kaurane-type diterpenes 14:546 enantioselective synthesis of 14:546 ent-Kaurenate 27:305 ent-Kaurene 15:16,135 ent-Kaurene glycoside 15:16-18;27:14, 22 from Stevia rebaudiana 15:16-18 suavloside A 27:14,22 suavloside B 27:14,22 suavioside G 27:14,22 suavioside H 27:14,22 suavloside I 27:14,22 suavloside J 27:14,22 Kaurene-type diterpenoids 2:280 Kaurenoic acid 6:186;25:242 GA12 aldehyde from 6:171,172 6,7-seco-ent-Kaurenoid diterpenoid 15:136 ent-Kaurenoids 15:112 8,9-seco-ent-Kaurenoids 15:112 ent-Kaurenol 30:713 structure of 30:713 Kawada's synthesis 30:30-33 of (-)-pironetin 30:30-33 Kawain 22:540,529 Kawin 13:660 from Piper methysticum 13:660 Kazinol A 28:17 antioxidant activity of 28:17 as tyrosinase inhibitor 28:17 as platelet aggregation inhibitor 28:17 Kazinol B 28:17,226,230 anti-human immunodeficiency virus (HIV) activity of 28:226 as cyclooxygenase 28:17 as platelet aggregation inhibitor
455
28:17 biological activity of 28:230 Kazinol C 28:210 from moraceous plants 28:210 Kazinol E 28:210 from moraceous plants 28:210 Kazinol F 28:16,210,230 antioxidant activity of 28:16 as tyrosinase by inhibitor 28:16 biological activity of 28:230 from moraceous plants 28:210 Kazinol J 28:210 from moraceous plants 28:210 Kazinol M 28:210 from moraceous plants 28:210 Kazinol N 28:210;28:230 from moraceous plants 28:210 biological activity of 28:230 Kazmaier's modification 26:1227 of Ireland-Claisen rearrangement 26:1227 KB activities 20:81 KB cells cytotoxicity assay 30:733 determination of cytotoxic activity 30:733 KB-1 28:229 biological activity of 28:229 KB-3 28:229 biological activity of 28:229 KB-16 (human oral epidermal carcinoma) 30:588 activity of (-)-deoxypodophyllotoxin against 30:588 activity of (-)-yatein against 30:588 K-cells-IL2-activated killer cells 25:273 effect of Actinoplanes sp. 25:777 KCI-depolarized rat portal vein 30:748 KDG 30:441,431 from glyceraldehyde 30:431 KDN 30:421,422,433,440,444,448,462 configuration of 30:463 conversion of 30:462 from membrane polysialoglycoproteins 30:422 from non-carbohydrate sources 30:462 from oxalacetic acid 30:433
from rainbow trout eggs 30:422 in cancer cells 30:422 in human fetal card red blood cells 30:422 oncotetal antigen properties of 30:422 preparation of 30:440 structure of 30:421 KDO 13:207,210;30:421,441,449, 465,471 Aug6 synthesis of 30:465 debenzylation of 30:441 hydrogenolysis in 30:441 intramolecular cyclization of 30:441 modifications of 30:465 Pettus synthesis of 30:471 synthesis of 30:441 via cobaltoxime 30:449 structure of 30:421 KDO analogs 30:430 synthesis of 30:430 KDO derivative 30:433,438,455 anomeric mixture of 30:433 KDO synthesis 30:448,450,456 photochemical 30:448 radical cross-coupling in 30:448 radical elongation process in 30:450 via exo-glycals 30:456 Keck DCC protocol 26:1230 Keck method 11:157 Kedarcidin 25:796 Kedarcidin chromophore 25:797 Kedde reagent 19:753 Keenamide A 25:887,888;28:652 as cyclic hexapeptide 28:652 as cytotoxic agent 28:652 Kelly procedure 10:111 Kemebakaurin 15:135 Kende 29:380,384 steganes synthesis by 29:380,384 Kent method 6:386 Keramadine 21:68 Keramakide D 23:220 Keramamide A 23:220 Keramamide B 23:220 Keramamide C 23:220 Keramamide F 23:220
456
Keramamide K 26:1183 Keramamide L 26:1183 Keramamides 25:885 Keramamides B-J 26:1181-1183 Keramamides F 25:884 Keramamides G 25:884 Keramamides H 25:884 Keramamides J 25:884 Keramamides K 25:884 Keratinocytes 12:393 by staurosporine 12:393 tumor promoter in 12:393 Kermesic acid 20:768 Kerriamycin 5:596 isotetracenon antibiotic 5:596 ' Kerriamycin A 5:596 (+)-Kessane 14:365 Ketal 8:160 trans-Ketalization 4:8,9 acid catalyzed 4:8,9 Ketalization 6:73,82,83,85 regioselective 11:41,42 Ketalized Diels-Alder type adducts 17:458 Ketamine 18:680 Keten acetals 4:357 Diels-Alder reaction with 4:357 Ketene complex 16:406 Ketene dithioacetal derivative 12:156,157 preparation of 12:156,157 Ketene dithioacetal S,S-diozides 6:733 synthesis of 6:33,334 Ketene silyl acetals 4:463,464 Ketene-imine cycloaddition 4:440,470472,474 1,2-diastereoselection 4:472 in Bose reaction 4:440,470 Ketenylidene-triphenylphosphorane 4:569,572 ec-Keto acetals 14:500,501 diastereoselective reduction of 1:622 from (-)-(2S,3S)- 1,4-dimethoxy2,3-butanediol LiAIHareduction of 14:500,501 Michael addition of 14:500,501 with methyl addition of 14:510
~-Keto acetals 14:497-499 addition of organometallic reagents to 14:497-499 diastereoselective 14:497,498 from (+)-(2R,3R)- 1,4-dimethoxy2,3-butanediol 14:497-500 from (R, R)-2,4-pentanediol 14:497,499 LiAIH4-reduction of 14:499,500 NaBH4-reduction of 14:500 13-Keto acid 8:384 ;25:165 decarboxylation of 8:297 trans-f3-Keto ester 4:437 from azetidinone 4:437 [3-Keto esters 4:436,439 in asymmetric hydrogenation 4:439 13-Keto thioester 11:195 reduction of 11:195 2-Keto-3-deoxy-6-phosphogluconate (KDPG) aldolase 30:424 structure of 30:424 2-Keto-3-deoxy-gluconate (KDG) aldolase 30:424 structure of 30:424 3-Keto-4c~-H-germacran- 1(10), 11( 13)dien-6,12-olide 27:563 4-Keto-5-methyl-trans-decalins 9:30 2-Keto-8 c~-hydroxy-5c~,6cx,7 ~H- guaian1(10),3 (4), 11( 13)-trien-6,12-olide 27:580 [3-Ketoacyl-ACP reductase 22:265 dehydratase (DH) 22:265 [3-Ketoacyl-ACP synthase 22:265 3-Ketoadociaquinone A 17:33;25:861 ot-Ketoamide 11:286 from aminoketal 11:286 [3-Ketoamide 12:162;25:785 asymmetric hydrogenation of 12:162 4-unsubstituted [3-1actam from 12:162 cx-Ketobutyric acid 13:319 Ketocarotenoids 21:305 Ketoconazole 22:60 Ketodeoxoscalarin 17:10 3-Ketodociaquinone A 25:862 3-Ketoepitaondiol 17:8
457 [3-Ketoester 6:429,430;14:652,653 [3-Ketoester enolization 14:734 c~-Ketoglutaric acid 9:542,543,553 c~-Ketogluturate 26:638 4-Ketoheptanolide 19:422 Ketohexopyranose nucleosides 4:248-253 5-Keto-imine intermediate 6:480,481 benzodiazonin-3-one from 6:480,481 7-Ketoisodrimenin 20:469 7-Ketoisodrimenin-5-ene 20:469 bis-c~-Ketol astaxanthin 6:152,153,161 cx-Ketol rearrangement 11:53,54 Ketolactam 6:510-513,602 ellipticine derivatives from 6:510,511 Ketologanin 7:470 cx-Ketols 27:72 y-Ketols 27:72 ent- 13-epi-Ketomanoyl oxides 25:260 Ketone 5:782,783 formation by epoxide rearrangement 5:782,783 Ketone reduction 1:415,417 Luche's conditions 1:415,417 stereoselective 1:415,417 to equatorial alcohol 1:415,417 with axial hydride attack 1:413, 415 with NaBHa-CeC13 1:413,419 Ketonucleosides 19:512 biological activity in 4:253 synthesis of 19:512 3'-Ketonucleosides 19:513 Ketopelenolide 27:564 Ketopelenolide A 7:231 6-Keto-PGFza 25:595 Ketophosphonate 6:275-277 from lithiomethylphosphonate 6:276 macrolide from 6:276,277 (1S)-Ketopinic acid 12:417 from (-)-camphorsulfonic acid 12:417 Ketopinic acid 12:417 reduction of 12:417 4-subsituted 2-oxazolidinones
from 12:416,417 with L-Selectride 12:417 (+)-trans-Ketopinic acid 4:640,641 3-(IS)-Ketopinyl-2-oxazolone 12:419-422 methoxybromination of 12:419-422 methoxyselenylation of 12:421,422
trans-5-bromo-4-methoxy
derivatives from 12:419-421 reversed zt facial selection in 12:419-422 Ketoprofen 6:323 3-Ketopropyl- 19R-heyneanine 9:171 2-Ketopupukeanone 6:82 (+)-2-isocyanopupukeanane from 6:82 Ketopyranose nucleosides 4:248 3-Ketoreductase 19:648 Ketoreductase 25:501 Ketoresorcinol 19:226 19-Keto-soyasapogenol B 25:184 A-nor-Ketosteroid 2:163 A-seco-6-Ketosteroid 2:169 Cotton effect of 2:169 N-Keto-stypodiol diacetate 25:591 Ketosugars 4:353,354 Grignard reactions with 4:353, 354 f3-Ketosulfoxides 4:502 reaction with enolate anions 4:502 reduction of 4:502-504 synthesis of carbohydrates 4:504-512 synthesis of macrolides 4:513-512 3-Ketotrichothecene 6:229 3cx-hydroxytrichothecene from 6:229 reduction of 6:229 8-Ketotrichothecenes 6:230,231,234, 235 Ketotriol asadanin 17:369 Ketourethane 12:303 11-Keto-fl-boswellic acid 22:128
458 cx-Keto-[3,y-unsaturated acetal 14:496 addition of Grignard reagents 14:496 Kexin 25:390 Kexin-like subtilases 25:389,390 Khan's method 21:742 for synthesis of chalcone 21:742 Khaya grandifoliola 5:700 Khaya ivorensis A. 22:524 for convulsions in children 22:524 Khaya senegalensis A. 22:524 for convulsions in children 22:524 KHMDS 22:229 Khusimone 3:32 synthesis of 3:32 (+)-Khusimone 4:674 Kibayashi' s group 29:432 marine alkaloids synthesis by 29:432 Kidamycin "aglycone" 11:136 antitumor antibiotics 11:136 O-methyl derivative of 11:137 1-oxabenz [a] anthracene 11:136 synthesis of 11:135-139 Kidney disorders 26:50 Herniaria hirsuta in 26:50 Kidney disturbances 30:207 use of Phyllanthus (genus) in 207 trans-Kielcorin B 26:259 Kievetone 25:546 Kigelia africana 7:406 Kigelia pinnata 23:342;29:747 Kiheisterone C 25:795 Kijanimicin 19:118 L-Kijanose 19:118 Kikumycin 5:553,554 Kikumycin B 5:553 Kinesin motors 25:695 inhibitor of 25:695 Kinetic characteristics 27:350 ofisomerization process 27:350 Kinetic deprotonation 11:337,338 of 2 cycl0hexen-l-one 11:337, 338 of enone 11:368 Kinetic isotope effect 7:56,57
Kinetic parameters 7:65,66;27:351 ofcellobiose analogues 7:65,66 of lactose analogues 7:67.68 of methyl [3-gentiobioside 7:52 of methyl [~-lactoside 7:52,54 of phenyl [3-D-glucopyranoside derivatives 7:55,56 Kinetic resolution 1:508,698;3:23, 19:478 by Sharpless epoxidation 4:342 of secondary 2-furylcarbinols 19:478 under Sharpless epoxidation conditions 19:478 Kinetic studies 27:857 of cell 27:857 Kinetin 26:640 Kinetin (6-furfurylaminopurine) 7:90 Kinetoplastid flagellates 2:298 polysaccharides as markers 2:298 Kingiside 16:307 from Lonicera morrowii A. Gray 16:307 Kinin formation 30:204 inhibition of 30:204 Kinin system 22:115 Kinoprene 13:667 Kirby reaction 8:76 Kirk-Petrow reaction 10:409 Kirschsteinin 22:72 Kishi synthesis 13:436-442,443,457, 458,461 of mitomycins 13:4-10,25,26,29 Kishi's retrosynthesis 26:1231 of onnamide 26:1231 Kishi's rule 1:404,130,163,167,168,171, 175;4:178,181,183,184,188,197,202, 203,705 Kishi's-model 4:503,504 Klaineanone 11:74-76 synthesis of 11:74-76 Klebsiella 12:63;26:1155 Klebsiella aerogenes 26:1263,1269 Klebsiella pneumoniae 5:106,308,325; 12:400;20:712;23:136,474 ;25:258, 259;26:402 Klemer fragmentation 3:201,202
459
Klemer-Rhodomeyer reaction 1:510, 511 Kloechera corticis 25:143 Kloeckera africana 5:283 Kloeckera magna 1:283,701 in microbial reduction 6:13 Kluyveromices sp. 13:302 Kluyveromyces fragilis 26:338 Kluyveromyces lactis 26:1127 Klyne's rule 26:8 of molecular rotation 26:8 Klyne-Hudson rule 15:207 Km values 30:95 oflipase activity 30:95 Knapp and Sharma 29:214 miltirone synthesis by 29:214 Knema elegans 21:591 Knemidocoptes pilae 28:415 Knoevenagel condensation 6:53,67,68, 316,320,328,331,334;24:36,37 in 14-epi-upial synthesis 6:67,68 Knoevenagel condition 11:140 Knoevenagel cyclisation 9:341 Knoevenagel reaction 13:109 Knoevenagel-Doebner condensation 24:717,718 Knoevenagel-type reaction 7:475 KO 30:421 structure of 30:421 Kobophenol A&B 26:535,558,560,561 Kobusin 26:200,231 Kochia prostrata 22:524 Kochia scoparia 24:273 Kocienski-Lythgoe condensation 4:602, 603 Kocienski-Lythgoe-Julia olefination reaction 11:393-395 Kodo-cytochalasin-1 and 2 15:353 Koelreuteria henryi 27:842;29:581 Koenigs-Knorr condensation 3:199 modification of 3:199 Koenigs-Knorr coupling (AgzCO3AgCLO4) 1:419,420 Koenigs-Knorr procedure 10:571 Koenigs-Knorr reaction 6:395;8:206, 258,359,363 Koenigs-Knorr synthesis 10:466 Koga 29:386 steganes synthesis by 29:386
Koga's method 11:241,242 of asymmetrization 11:241,242 of ~-symmetric ketones 11:241,242 Koidzumiol 7:218 Kojic acid 12:269;21:587 O-alkylation of 12:269 with allylic bromide 12:269 [4+2] cycloaddition of 5:799 from Taxus mairei 20:118 Kokoona zeylanica 5:743-745;30:642, 674 celastrahydride from 30:642 D:A-friedo oleananes from 7:147-149 phenolic triterpenes from 7:147-149 triterpene quinone methide from 7:147-149 Kokoondiol 5:744-746,147,148 Kokoonol 7:147,148 3,27-diozy derivative 5:745 3,21,27-trioxy derivative 5:745 Kokum soap 23:656 Kokusagine 21:68 Kokzeylanol 5:744-746,147,148 Kokzeylanonol 7:147,148 Kolavenic acid 6:28 agelasin B from 6:28 from Solidago species 6:28 Kolbe reaction 9:371 Koltin 22:62 Komaroine 14:762 from Nitraria komarovii 14:762 Komarovicine 14:762 from Nitraria komarovii 14:762 from quinoline-8-carboxaldehyde 14:763 komarovidine from 14:763 komarovine from 14:763 synthesis of 14:763 via Pictet-Spengler reaction 14:763 Komarovidine 14:758,763,764 biosynthesis of 14:763,764 from komarovicine 14:763 from Nitraria komarovii 14:762 from quinoline-5-carboxylic acid 14:763
460
synthesis of 14:763 via Bischler-Napieralski condensation 14:763 Komarovine 14:763,764 biosynthesis of 14:763,764 from komarovicine 14:763 from Nitraria komarovii 14:762 Komarovinine 14:763,764 biosynthesis of 14:763,764 from Nitraria komarovii 14:762 from quinoline-6-carboxaldehyde 14:763 synthesis of 14:763 via Pictet-Spengler reaction 14:763 Komayum 23:655 Kombamide 26:1184 Konbuacidin 25:798 Konbuacidin A 25:711,798 Konevenagel-type reaction 11:139 K6nigs-Knorr coupling 21:170 Koningic acid 21:229 Konjac glucomannan 26:1149 Kopsia dasyrachis Ridl. 21:128;29:363 kopsirachin from 21:128 Kopsidasinine 5:53,9:188,189 Kororamels 25:902 Korundamide A 26:822,823 Korupensamine C 20:449,451 from Ancistrocladus kerupensis 20:447 ent-Korupensamine D 20:440 Korupensamines A and B 20:443,451 from Ancistrocladus kerupensis 20:442 Koshikamide A 26:1193 Kotalagenin 16-acetate 30:645 ~3C NMR data of 30:645 ~H NMR data of 30:645 HMBC spectrum of 30:645 NOESY spectrum of 30:645 stereochemistry of 645 structure of 30:645 Koteconazole 2:423,441 Koumicin N-oxide 15:466,467 Koumicine 15:466,467 19(E)-Koumidine 15:466,467 from gardnerine 15:469
Koumine 15:475,476 from Gelsemium elegans 15:475,476 Koumine Nb-oxide 15:475 from Gelsemium elegans 15:475 Koumine-type alkaloids 15:475-477, 500-503 synthetic studies of 15:500-503 Kouminol 15:475 Kozikowski approach 12:20-22 for avermectin oxahydrindene subunit 12:20-22 Kozikowski's nitrile oxide 12:21,22 Kozikowski's retrosynthetic analysis 13:588 kP6 preprotoxin 25:389 Krameria triandra 26:204 scavenging activity of 26:204 Krapcho decarboxylation 18:246 Krapcho's thermal dealkoxycarbonylation 24:39 cx-Kratin 26:667 Kraus method 6:225,226;11:129 Krebs cycle 7:112,117,387;26:924,940 Krebs cycle enzymes 11:197 Krebs tricarboxylic acid cycle 6:252 Kresoxim methyl 22:250 Krohncke reaction 20:602 Krohncke's procedure 6:513 Krow 29:384 steganes synthesis by 29:384 Krukovine A 23:693 Krukovine B 23:693 Krukovine C 23:693 Krukovine D 23:693 Krukovine E 23:693 Kryptogenin 5:774 KSD assay 25:862 KT-5720 12:384-386 KT-5822 12:384-386 KT-5926 12:388 myosin inhibitor of 12:388 protein kinase inhibitor of 12:385,386 Kuanoniamine alkaloids 21:285 Kuanoniamine B 23:272 Kuanoniamines A-D 17:23;25:893,894, 995 Kuanoniamines C,D 21:269,220
461 Kudzusapogenol A 25:95 Kudzusapogenol A glycoside 25:103, 105 Kudzusapogenol B 25:97 Kudzusapogenol C 25:96 Kudzusaponln Ai 25:95 Kudzusaponln A2 25:95,104 Kudzusaponln A3 25:95,104 Kudzusaponln A4 25:95,104 Kudzusaponm A5 25:95,104 Kudzusaponm C~ 25:96,103 Kudzusaponln PA3 25:118 Kudzusaponln SAI 25:95 Kudzusaponln SA2 25:104 Kudzusaponln SA3 25:95 Kudzusaponln SA4 25:104 Kudzusaponm SB1 25:95 Kuehneromycin A 29:128,129 absolute stereochemistry of 29:129 effect on reverse transcriptases 29:128 related natural compounds 29:129 synthesis by Jauch 29:159 synthetic strategies of 29:129, 130 total synthesis of 29:148 transition states in synthesis of 29:161 Kuehne's synthesis 14:831-849 ofvinblastine 14:831-849 of vincristine 14:831-849 Kuepaloxane 25:787 Kuhn-Roth oxidation 11:210 Kulactone 9:300,305,308 Kumatakenin 28:226,229 anti-human immunodeficiency virus (HIV) activity of 28:226 biological activity of 28:229 Kumusine 26:1201 Kupffer celts 25:464,475 Kurarmine 9:150 Kurilogenin 7:280 from Duasmodactyla kurilensis 7:279 Kuriloside A 15:89 from Duasmodactyla kurilensis 15:89
Kurospongin 5:371 Kutney's synthesis 14:806-821 ofvinblastine 14:806-821 ofvincristine 14:806-821 Kuwajima's B-ring cyclization route 12:190 Kuwanon 28:212 biological activity of 28:212 Kuwanon C 28:210,230 biological activity of 28:230 from moraceous plants 28:210 Kuwanon E 28:210 from moraceous plants 28:210 Kuwanon G 17:451 ;28:201,209,221, 230 biological activity of 28:230 biosynthesis of 17:165 bombesin receptor antagonist of 28:221 from moraceous plants 28:201 hypotensive action of 28:209 optical rotation of 17:464 Kuwanon H 28:200,201,209,212,221, 222,223,225 anti-human immunodeficiency virus (HIV) activity of 28:226 as bombesin receptor antagonists 28:223 as GRP-induced DNA synthesis inhibitor 28:222 biological activity of 28:212 bombesin receptor antagonist of 28:221 from moraceous plants 28:201 hypotensive action of 28:200, 209 Kuwanon L 28:210 from moraceous plants 28:210 Kuwanon M 28:210,212 biological activity of 28:212 from moraceous plants 28:210 Kuwanon R 28:230 biological activity of 28:230 Kuwanons J 17:455 Kynurenic acid 26:965-968,970 Kynurenine 21:70;26:966,968-971,990, 998 Kyurenic acid 25:529
462
L-1210 leukemia cell 21:403,414 L-653,150 26:242 as PAF-induced inhibitor 26:242 Labd- 13(E)-en-8a, 15-diol 25:267 (E)-Labda-8(17), 12-diene- 15,16-dial 23:809 Labda-8(17), 13-dien- 15,12R-olid- 19-oic acid 29:101 activity in EBV bioassay system 29:101 (+)-Labda-8(20), 13-dien- 15-oic acid 6:56,57,111,117,120,125 (E)-8(17), 12-Labdadiene-15,16-dial 23:801 Labdadiene- 15,16-diol 11,15-hemiacetal (11-OH-8(17),12(E)-) 25:266 8(17), 12(E)-Labdadiene- 15,16-diol 25:265,266 Labdadienoic acid 25:248 5R, 8R,9R, 10R-Labdan- 13(6)-ene-8d, 15diol 25:258 Labdan-8(17), 13-dien-3fl- 15,18-triol 25:251 ent-Labdane 15:252;25:251 ent-Labd-8,13(E)-dien- 15-ol 25:249 ent-Labdane oxides 25:249 Labdane 25:241,244,256,259,261,266, 275,276,277 activities of 25:257 Labdane 13-O-glycosides 25:251 Labdane diterpenes 23:810 Labdane diterpenoids 1:662 Labdane F2 29:102 activity in PLA bioassay system 29:102 Labdane glycoside 25:251;27:14,22,24 baiyunoside 27:14,24 gandichandioside A 27:14,25 phlomisoside I 27:14,24 Labdane S 25:246,249 Labdane xylosides 25:252 Labdanes 10:408 Labdane-type diterpenoids 20:691; 21:692,721 Labdanum oil 25:253 (+)-(13E)-13-Labdene-8,15-diol 1:671, 672 Labiatae 7:96,118-120;21:605;25:921
Labiatae pinaceae 27:361 Labopghora variegata 25:729 Labophorins A and B 25:729 Laburnine 1:248,339 synthesis of 1:248,339 Lacarol 7:224 Laccaic acid C 20:277 Laccol 9:319 Lachnanthes tinctoria 4:618 Lachnanthocarpone 17:372 Lachnanthocarpone formation 4:618 Lachnates 17:372 Lachnella 26:462 Lachnophyllum ester 7:221 Lachnum papyraceum 25:781,785; 26:446 Lachnumol 25:785 Lachnumol A 26:446,447 Lachnumon 25:781,782 Lachnumore 25:757 Lacinartin 7:204,205,224 Laciniata furanone 9:532,533 Lac-permease 8:353 Lactam 1:325,326 O-methylation 1:325,326 13-Lactam 12:115,159-172;22:245 by 4CC 12:115 from [3-amino acids 12:115 C4-alkylation of 12:159-172 Lactam analogues 12:388 Lactam carbonyl 3:474 selective reduction of 3:474 [~-Lactam compounds 12:155-159 from D-amino acid 12:155-159 synthesis of 12:155-159 Lactam sulfoxide 3:109 cyclization of 3:109 [3-Lactamase 16:727 [3-Lactams 11:706-213 biosynthesis of 11:207-213 Lactams 17:573 170-NMR 17:573 8-Lactams 18:315 synthesis of 18:315 Lactarane 17:154 Lactarazulene 14:315 Lactarius camphoratus 17:156 Lactarius chrysorrheus 17:196
463
Lactarius circellatus 17:197 Lactarius controversus 17:198 Lactarius deceptivus 17:198 Lactarius deliciosus 17:198 Lactarius deterrimus 17:198 Lactarius flavidulus 17:198,201 Lactarius fuliginosus 17:153,201 Lactarius fulvissimus 17:200 Lactarius genus 17:153,156 sesquiterpenes from 17:159 Lactarius glaucescens 17:198 Lactarius glutinopallens 17:199 Lactarius glyciosmus 17:199 Lactarius helvus 17:199 Lactarius indigo 17:199 Lactarius lignyotus 17:200 Lactarius mitissimus 17:200;26:461 Lactarius necator 17:199 Lactarius pergamenus 17:198 Lactarius picinus 196,201 Lactarius piperatus 17:197,198 Lactarius quietus 17:196 Lactarius rufus 17:199 Lactarius scrobiculatus 17:153,196,197 Lactarius subvellereus 17:198 Lactarius thejogalus 17:200 Lactarius torminosus 17:196,197 Lactarius vellereus 17:153,196,197 Lactarius, metabolites 17:154 Lactase 10:498 Lactase phlorizin hydrolase 25:609 Lactate 12:223 synthesis of 12:223 (R)-Lactates 8:140 (S)-Lactates 8:140 Lactic acid 2:163;28:386 in honey 28:386 Lactiflorasyne 7:204 from Artemisia lactiflora 7:203 X-ray analysis of 7:203 Lactiflorenol 7:218 from Artemisia lactiflora 7:218 Lactobacillus helveticus 13:319 Lactobacillus plantarum 23:474 Lactobocillus sp. 25:257,924,927,928 Lactoferrin 22:327 [3-Lactoglobulin 30:840 Lactol 11:140,141
Lacto-N-biose I 10:459,461,467-471, 476 synthesis of 10:474,475 Lacto-N-biose II [GlcNAcl3(1-3) Gal] from oxazoline 10:474,475 y-Lactone 17:270;19:470 reduction of 19:470 Lactone 30:17,457 hydroboration-oxidation reaction of 30:457 hydrogenation of 19:469 methylation of 19:469 synthesis of 30:17 (4S,5S)-Lactone 8:296 S-Lactone 8:298,306 syn addition of 8:306 (4R)-Lactone 8:305,306 anti addition of 8:305,306 Lactone annulation 13:29-31 Lactone Claisen rearrangement 13:544, 596 Lactone methyl-isomerase 8:300 Lactone rearrangement fragmentation 3:96 Lactone synthesis 13:615-626 asymmetric synthesis of 13:621, 622 Lactone triflate 10:60 ring contraction reaction 10:605 to oxetane-2-carboxylate 10:605 Lactone unit 11:345-347 construction of 11:345-347 model studies on 11:345-347 of compactin and mevinoline 11:345-347 2,3-seco-22,29-Lactone-oleane- 12-ene2,3-dioic acid 3-methyl ester 30:650 structure of 30:650 5-Lactones 10:218 Lactones 3,157,171;10:385-388;14:557, 558 CD of 2:171 saturated 17:275 synthesis of 3,157,171; 10:385-388;14:557,558 unsaturated 17:27I via intramolecular hetero-DielsAlder reaction 14:557,558
464
Lactonisation 12:157,158 acid-catalyzed 12:157,158 by Gerlach's procedure 6:542, 543 of N-acetyl muramic acid 6:389, 390,395 of co-hydroxy-acids 8:233 with pyridinium acetate 11:84,85 Lacto-N-iso-octaosyl ceramide 10:461 Lacto-N-neo-hexaose 10:478,480 by double glycosylation 10:478 Lacto-N-neo-tetraose 10:462 from oxazoline 10:478 Lacto-N-tetraose 10:468 from Lactobacillus bifidus 10:468 Lactoperoxidase 19:455 Lactoquinomycin 11:128 Lactosamine 10:462 N-acetylation of 10:462 catalytic hydrogenation of 10:462 from 3-O-13-D-galactopyranosylD-arabinose 10:463 from D-lactal hexaacetate 10:464 from lactose 10:462-466 from monosaccharides 10:466,467 synthesis of 10:461,467,471 Lactosaminoglycan 10:460 Lactose 1:508,509,499 Lactose analogues 7:67,68 Lactosylceramide 18:796 N-(S)-Lactoyl-(S)-proline 13:482 Lactuca sativa L. 26:187;27:215,217 allelopathic interaction of 27:215 Lactuca virosa 20:8 Lactucin 20:8 Lactucopicrin 20:8 16-Oxo-8(17), 12(E)-Ladadiene- 15-oic acid 25:266 Ladenburg prism mechanism 7:362,263 Ladybird alkaloid 6:447 Laetisaria arvalis 21:187 Laetisaric acid 21:188,189 Laevigatoside 7:293 from Linckia laevigata 7:290 Laeviuscolosides F,G,H and I 15:64
Laevoglucosan 1:453 Lagascatriol 29:103 activity in COX bioassay system 29:103 activity in NO bioassay system 29:103 Lagenaria leucantha 29:615 Lagenidium callinectes 22:79 Lagerstoroemia 23:405 Lagerstroemia subcostata Koehne 1:368 Lagochilus sp. 22:524 Laguncularia racemosa 7:175 Lahoramine 1:207 synthesis of 1:207 Lahoricine 5:125,158,159 Lahorine 1:207 Lamalbid 7:471 Lambertianin A 23:416 (+)-Lambertic acid 10:407,640-642 synthesis of 14:640-642 Lamellariidae 17:21,22 Lamellarins A-D 17:22 Lamellarin A 23:248 Lamellarin B 23:248 Lamellarin C 23:248 Lamellarin D 23:248 Lamellarin E 23:248 Lamellarin F 23:248 Lamellarin G 23:248 Lamellarin H 23:248 Lamellarin M-triacetate 23:250 Lamellarin N 23:249 Lamellarin O 23:246 Lamellarin P 23:246 Lamellarin Q 23:246 Lamellarin R 23:246 Lamellarin T 23:249 Lamellarins 25:706 Lamellomorpha strongylata 26:1189 Lamiacea 21:584 Lamiide 7:463 acid rearrangement of 7:463 aglycone 7:463 Lamiide aglycone 7:475 reduction of 7:475 Lamiidol 7:467 Laminaceae 25:171
465
Laminarabiose 8:349 hydrolysis of 8:349 Laminaran 26:1121 from brown algae 26:1121 Laminaria abyssalis 30:400 sulphated polysaccharide (PS) from 30:400 Laminariajaponica Aresch. 30:56 fucoidan from 30:56 in arteriosclerosis treatment 30:56 in cancer treatment 30:56 in hyperlipidemia treatment 30:56 Laminaria ochroleuca 22:524 Laminaria pedicularioides 25:868 Laminaria sp. 25:724;26:1121 Laminariales 26:478 Laminin a~ 27:806 Laminine 26:478 (-)-Laminitol 18:434 Lamiol 7:440,455,459,460,464-466 Lamiol aglycone 7:475 reduction of 7:475 Lamium 26:392 Lamivudine 24:488 as anti-viral agent 24:488 Lamorouxia multifida 24:839 glucoside iridoid of 24:839 Lamorouxia rhinanthifolia 24:839 Lamorouxia sp. 24:839 Lamotrigine 22:507 (+)-Lamprolobine 18:367 Lampteromyces 29:271 Lampteromyces japonicus 26:706 Lanatoside A-E 15:362 Lancerodiol 5:724,725,731 p-methoxybenzoate of 5:724, 725,731 Lancerotriol ester 5:732 Lancet-shaped follicular mites 28:410 as cause of demodectic mange 28:410 Langmuir-Blodgett films 25:334 Lankacidin 21:316 Lankaumycin 4:255 Lanoslane 25:49,57 Lanosprazol 25:612 Lanost-9(11)-ene 27:468
Lanostane 9:267,302 16a-Lanostane carboxylic acids hydroxydehydrotrametenolic acid 25:57 Lanostane triterpenes 22:105,117 Lanostanes 25:61 O- 16a-hydroxytrametenolic acid3-acetate 25:61 pachymic acid 25:61 poricoic acid B 25:61 abiesonic acid methyl ester 25:64 Lanostene triterpenes 10:151 Lanosterol 7:266;21:314;22:59,255 Lanosterol ester 9:467 Lanosterol glycosides 21:644 Lansic acid 1:658-660 synthesis of 1:658-660 Lansiolic acid 1:648-660 synthesis of 1:648-660 Lansioside A,B,C 1:658 Lansium domesticum 1:658 Lantadene A 25:64 Lantadene B 25:59,64,66 Lantadene C 25:59 Lantana camara L. 22:524;23:487,521, 523 ;27:377,836,29:586 as anticonvulsant agent 22:524 polar constituents from 23:523 Lanthella 25:719 Lanthella basta 10:632 bastaxanthins from 6:150 Lanularic acid 2:287,288 Lapachol 27:851 ;29:734;30:317 biosynthesis of 734 [3-1apachone (21) 27:851 teratogenic potential of 30:317 Lapachol methylether 26:66 [3-Lapachone 27:851 Lapachone 30:310 structure of 30:310 Lapachone antitumor effects 29:744 against A549 human breast cancer cell 29:745 against Cdc25 phosphatases 29:745 against DNA topoisomerase 29:746 against human cancer cell lines
466
29:744 against ovarian adenocarcinoma 29:744 via DNA modification 29:745 of 2-methyl-(Z)-4-phenylimino) naphth[2,3-d]oxazol-9-one 29:744 proteasome inhibition by 29:746 through multistage carcinogenesis 29:746 Lapdap 26:783 Lapidin 5:722,723;29:91 activity in CRG assay system 29:91 Lapidolin 5:722,723 Lapiferine 5:722,723 Lapiferinin 5:722,723 Lapiferol 5:736 ~3C-NMR spectrum of 5:736 isovalerate 5:736 Lapinone 26:803 Lappaconitine 25:528 Lappaconititine 25:528 Lappaol B 5:497,498 c~-1,5-L-arabino-[3-3,6-D-galactan 27:510 Lardoglyphus konoi 1:696;14:487 (-)-lardolure from 14:487 pheromone of 1:696 Lardolure 1:696 from acarid mite 1:696 synthesis of 1:696 (-)-Lardolure 14:487 from Lardoglyphus konoi 14:487 synthesis of 14:487 L-arginineanalogues 25:471 (+)-Lariciresinol 20:620;26:177,188, 205,219 Lariciresinol 26:199 (+)-Lariciresinol 26:219;27:503 as chemopreventive agent 26:219 (+)-Lariciresinol ferulate 20:620 (+)-Lariciresinol p-coumarate 20:620 7S, 8R, 8' R-(-)- Laric ires ino 1-4,4' -bis-O[3-D-glucopyranoside 26:199 Lariciresinol-4[3-D-glucoside 26:199
Larikaempferic acid methyl ester 29:100 activity in EBV assay system 29:100 Larix decidua 17:332 Larix kaempferi 29:99 Larix leptolepis 20:613;26:185 Larmor frequency 9:127,131 Larrea divaricata 17:315 Larrea tridentata 5:9;26:187,205,249 Larreantin 5:9-11 Larus asrgentatus 5:837 hemoglobin components of 5:837 Larus philadelphia 5:837 hemoglobin components of 5:837 Larvotoxic 17:102 Lasallia papulosa 5:311 Lasallia pensylvania 5:311 Lasalocid A 11:196 synthesis of 10:424,715 Laser desorption 9:487 Laser desorption mass spectrometry 5:632,633;25:330,331 Laser Field Desorption (LD) 24:138 of saponins 24:138 Laserpitine 5:725,727,734 Laserpitium halleri subsp, halleri 5:728 Laserpitium latifolium 5:725,727 Lasiantheae fruticosa 5:728 Lasidiol angelate 5:728,729 Lasioderma serricorne (cigarette beetle) 1:695,275 serricomin from 14:275 Lasiodiplodia theobromae 6:557,290, 477 Lasiodiplodin 9:288,289 Lasiodonin 15:172,173 from Rabdosia gaponica var. glaucocalyx 15:172 from Rabdosia macrophylla 15:173 from Rabdosia parvifolia 15:173 Lasioglossumze phyrum 8:222 Lasiokaurin 15:172 from Rabdosia henryi 15:172 from Rabdosiajaponica 15:172 from Rabdosia longituba 15:172
467
from Rabdosia macrophylla 15:172 Lasiokaurinol 15:172 Lasius niger 6:454 Laspeyresia pomonella 26:231 (-)-Lasubine 16:477 synthesis of 16:477 Lasubine I 1:367-370 synthesis of 1:367-370 Lasubine II 1:367 4-epi-Lasubine II 1:368 2-epi-Lasubine II 1:369 (+)-Lat A 25:874 (+)-Lat B 25:874 Lat C 25:875 Lat D 25:875 Lat M 25:874,875 Lat S 25:874,875 "Latent Michael-acceptor" 12:99 Laternula elliptica 25:723 Lathyrus odoratus 26:1268 Lathyrus palustris var. pilosus 25:93 Lathyrus satives 25:529;26:1268 Latrunculi B 25:732 Latrunculia apicalis 18:716;25:708 Latrunculia brevis 9:20;25:822 trunculin-A,B from 9:20 Latrunculia rnagnifica 21:96;25:874; 28:688 6,7-epoxy-latrunculin from 28:689 latrunculin B from 21:96 latrunculin M from 28:689 Latrunculia purpurea 25:760,822 Latrunculia sp. 21:311;25:758,822; 28:685 discorhabdin A from 28:686 Latrunculin A 17:13;19:568;25:733; 28:688 as ichthyotoxins 28:688 2-thiazolidinone moiety of 28:688 Latrunculin magnifica 17:14 Latrunculins 19:550;25:874 Latrunulia monocytogenes 25:450 Lats A and B 25:874,875 Laucopolargonidin 25:653 Laudanine 18:49,73
(+)-Laudanosine 16:506 oxidation of 16:506 S-Laudanosine 16:507 Laudanosine 21:57;22:9;30:564,595, 596 antimalarial activity of 30:595 antiplasmodial activity of 30:596 effect on antiplasmodial activity 30:596 (+)-Laudanosine methiodide 6:475,476 cis-Laudanosine N-oxide 6:468 2,3-benzoxazepine derivative from 6:468 Meisenheimer rearrangement product from 6:468 (+)-Laudanosine N-oxide 6:472 preparation of 6:472 themolysis of 6:472 Laulimalide 19:568;30:5 as microtubule stabilizing agent 30:5 Launaea cornuta 22:524 for epilepsy 22:524 Lauraceae 25:943 Laurales 30:560 order of 30:560 Laurane 9:81 Laurediols 19:454 Laureline 3:424,425 synthesis of 3:424,425 Laurenan 10:232 Laurence genus 25:249 Laurencenynes 19:454 Laurencia brongriartii 25:863 Laurencia concinna 6:24 concinnidiol from 6:24 Laurencia glandulifera 6:63 glanduliferol from 6:63 Laurencia implicata 18:633;26:808,809 brasilane sesquiterpene from 18:633 Laurenciajaponensis 25:803 Laurencia majuscula 6:60 bromochamigrene from 6:60 Laurencia nipponica 6:41,63 (-)-(2R, 6S, 9S)-2,8-dibromo- 9hydroxy-o~-chamigrene from 6:63
468
(+)-isocycloeudesomol from 6:41 Laurencia obtusa 5:363;8:625 brasilenol from 6:6 brasilenol acetate from 6:6 epi-brasilenol from 6:6 Laurencia okamurai 19:454 Laurencia pacifica 6:63 (+)-2-bromo- [3-chamigrene from 6:63 Laurencia perforata 6:29,30,56 Laurencia pinnata 6:9,26;21:252 laurepinnacin from 21:252 Laurencia pinnatifida 5:216,363,81-8 marine sesquiterpenes from 9:81-83 Laurencia poitei 6:35 poitediol from 6:35 Laurencia rigida 25:783 Laurencia saitoi 25:788 Laurencia snyderae 6:6,30 epiguadalupol from 6:30 guadalupol from 6:30 isoconcinndiol from 6:30 Laurencia sp. 5:361-363,368,370; 25:701 ;6:24,59,60;9:8;10:231 (-)-aplysin-20 from 6:24 10-bromo-c~-chamigrene from 6:60 spirobicarbocyclic chamigranes from 6:59 Laurencia subopposita 6:10 oppositol from 6:9 prepinnaterpene from 6:9 Laurencia venusia 5:361 Laurencin 10:201;19:411 total synthesis of 10:202 absolute stereochemistry of 19:422 EI-HRMS of 19:422 IR spectrum of 19:422 isolation of 19:421 Laurenene 3:6,25,61,117;13:19 from Dacrydium cuprassinum 13:19 X-ray crystal analysis of 13:19, 20 Laurenica 25:701 Laurenica majuscula 25:702
Laurenica nidifica 25:702 Laurenica nipponica 25:702 Laurenobiolide 7:231 (-)-Laurenyne 10:225 synthesis of 10:225 Laurenyne 19:411 Lauric acid 21:595 Laurifine 6:477,478 synthesis of 6:477,478 Laurifinine 6:477,478 synthesis of 6:477,478 Laurilia tsugicola 26:703 Laurinterol 17:7 Laurol (7-hydroxy-3,4-epoxy-laurane) 9:81,82,87 Laurolenal 2:170 (+)-Laurotetanine 30:563,564,589,594 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 as platelet aggregation inhibitor 30:594 cytotoxic effect of 30:589 N-Lauroylvaline 6:320 synthesis of 6:320 Laurus azorica 26:850 Laurus nobilis 21:599 Laurycolactone A 11:71 Lauryl chloride 6:429 protection with 6:429 N-Lauryl-6-methyl-2-piperidone 6:430, 431 pyrolysis of 6:430,431 Lauthisan 10:213 synthesis of 10:213 (+)-Lauthisan 10:232;19:412,420 synthesis of 10:232;19:412 cis-Lauthisan 10:235 synthesis of 10:235 Lavandula angustifolia 7:94,95,108, 109,118,119,125,126;21:612;27:374; 28:411,412 acaricidal activity of 28:412 essential oil of 28:411 constituents of 28:411 Lavandula latifolia 29:91 Lavandula sp. 7:125;21:617;22:524 Lavandulol 7:126
469
Lavendamycin 3:385 synthesis of 3:387 Lavendustin 15:444-447 Lavendustin A and B 15:445 Lawencia clavidormis 25:770 Lawesson's reagent 3:354,355;8:126, 127 ;10:565 ;12:301,305,322 Lawsone 26:638;29:736;30:314 biosynthesis of 29:736 structure of 30:314 Lawsonia alba 26:837 Lawsonia inermis 30:336 for decoration 30:336 Laxative 30:72 use of Angelica keiskei as 30:72 Laxative activity 30:304-307 of anthranoid compounds 30:304-307 Laxative drugs 30:303 aloes as 30:303 caseara as 30:303 rhubarb as 30:303 senna as 30:303 Laxative effect 30:305 of aglycones 30:305 by damaging epithelial cells 30:305 LC chromatogram 19:771 LC/ESI-MS analyses 28:290 of sulfated tea catechins 28:290 of urinary glucuronid 28:290 LC/MS total ion chromatograms with 29:666 low cost operation of 29:656 of aqueous extracts 29:653 TLC analysis of 29:652 weight distribution in 29:653 L-Camavanine 341 LC-mass spectrometry 21:579 LC-MS 21:555,556.557 LC-MS-MS 21:555,558 LDs0 7:280,284,306 LDL peroxidation 30:224 induction by AAPH 30:224 induction by Cu 2+ 30:224 Leachianol A-G 26:535,555,563,564 Lead tetraacetate 1:439 oxidation of diol 1:439 oxidation of ring C of yohimbine
1:158,439 glucuronide linkage cleavage by 7:156-158 Lead tetraacetate oxidation 5:788 Leaf spot disease 4:601 Leathesia difformis 30:405 Lebistes retculatus 26:689 Leccinum 29:271 Lectins 7:129;24:523,524 inactivation of(HVF) 24:523, 524 Ledebouriella seseloides 22:524 for convulsions and spasms 22:524 Ledol 20:17,19 Ledum palustre 20:17 Leech repellent 5:745 Leepacine 5:150-152 Lefevreiosides A~, A2, C and D 15:96 NO-Leghemoglobin complex 26:937 Legionella pneumophila 13:155 Legislation 13:337-340 Legumes 23:341 Leguminosae 21:3,91,139,611;25:92, 180,186,188,246,248,465;26:637, 871,931 ;27:443,766 saponins from 21:642 Leguminous isoflavone reductase (IFRs) 25:319 Leishma braziliensis 2:311 Leishmania 2:311-314;18:791,793,794; 26:779,780,783,786,789,790,793, 801,803,805,807,808,810,821,822, 824,828,830 glycocomplexes of 2:311-314 polysaccharides of 2:311-314 Leishmania adleria 2:311,313 against kala-azar 2:313 immunity against kala-azar 2:313 Leishmania amazonensis 2:298,794; 23:707 ;26:229,887 amastigotes of 26:828 promastigotes of 26:828 Leishmania braziliensis 29:749 Leishmania decemlineata 26:851859,860,863-866 Leishmania donovani 2:311,312; 21:744 ;25:254,260;26:791,794,797,
470 800,804,805,806,819,821,828; 29:749 glycopetidophosphophingolipid of 2:312 polysaccharides of 2:311,312 Leishmania enrietti 2:314;29:749 carbohydrates in 2:314 Leishmania infantum 21:674;26:810; 29:749 Leishmania major 26:230,784,791,800, 805,810,811 ;29:749 Leishmania mexicana amazonensis 2:314 carbohydrates in 2:314 Leishmania panamensis 21:674;26:821, 822 Leishmania tarentolae 2:298,311 carbohydrates in 2:311,314 Leishmania tropica 21:674;26:802 Leishmania tropica major 2:314 polysaccharides in 2:314 Leishmaniases 2:293;26:781,783, 784,785,793 LELA 29:585 effects on acetyl-11-keto-13boswellic acid (triter-pene) 29:585 Lemieuix oxidation 18:171 Lemieuix-Johnson oxidation 4:592,593; 10:591-592;13:613;18:81 Lemieux-Nagabhushan reaction 14:145 Lemieux-von Rudloff oxidation 1:261-262;6:291,292 Lemmatoxin 7:428 molluscicidal activity of 7:428 Lemmatoxin-C 7:428 molluscicidal activity of 7:428 Lemna bioassay 9:386,387,389,390; 15:344 Lemna gibba 27:330 Lemna minor (duckweed) 9:383,384, 386,387,389,390 Lemnalia africana 25:695 Lemon 23:747 Lemon juice phenolics 23:748 HPLC chromatogram of 23:748 Lendenfeldia chondrodes 25:703 Lennoxamine 1:163,164 synthesis of 1:176,177
Lens culinaris 21:526;26:1263 Lens esculenta 25:93 Lentinan 5:279;25:450;23:115,122,123 antitumor activity of 5:317 13C-NMR spectra of 23:122 Lentinus edodes 5:287,288,316;23:111, 115,131;25:450 Lenzites betulina 29:266;291 Leocarpus fragilis 21:414 Leontice leontopetalum 9:153 Leontodon hispidus 29:90 Leonurus cardiaca L. 22:525;30:273 for epilepsy 22:525 isoquercitrin from 30:273 Leonurus hereteropyllus 25:272 Lepidine 3:396 Lepidium sativum 21:98,109;25:781; 27:217;28:400 in tick toxicity 28:400 Lepidoglyphus 28:432 Lepidoptera 9:322,772;22:371 ;22:376, 381 Leprae 26:1155 c~,13-Leprosols 9:322,338,345 Leptine I 7:18;21:84 Leptinidine (23 [3-hydroxysolanidine) 7:18,22 Leptinotarsa decemlineata 26:850,854, 855,869-872,874,876 Leptochilus acolhuus 5:223,224,253 Leptoclinides dubius 25:719 Leptocoris trivittatus 22:386 Leptodactylin 15:328 Leptodontium elatius 21:193;22:253; 23:344 Leptogenys diminuta 11:415 (3R,4S)-4-methyl-3-heptanol from 11:415 Leptogorgia virgulata 17:99 Leptomonas collosoma 2:301 Leptomonas samueli 2:298 polysaccharides of 2:301 Leptophyllin-A 20:486,487 Leptophyllin-B 20:486,487 Leptosin B 25:839 Leptosin C 25:839,840 Leptosin D 25:839 Leptosin E 25:839 Leptosin F 25:839
471
Leptosin G 25:839 Leptosin G~ 25:839 Leptosin G2 25:839 Leptosin H 25:839 Leptosin I 25:839 Leptosin J 25:839 Leptosin K 25:839,840 Leptosin K2 25:839 Leptosin KI 25:839 Leptosins 25:838,839 Leptosm A 25:839,840 Leptosphaeria oraemasis 22:72 Leptosphaeria sp. 25:839,901 Lepto~phaerisa oraemaris 23:344 LeSBTI 25:392 Lesion 22:441 Lespedeza capitata 29:580 Lespedeza sericea 22:95 Lesquerella sp. 13:310 Lethality bioassay 9:385,387,388, of brine shrimp 9:385,387,388, 399,400 Lethaloxin 26:451 Letharia vulpina 5:310,311,313 Lethasterias nanimensis chelifera 15:59 Leucadendron 4:712 Leucaena leucocephala 26:1142,1148 galactomannans from 26:1148 Leucaena spp. 26:1139 Leucas lavandulifolia 22:525 for convulsion, epileptic seizures and coughing spasms 22:525 Leucas zeylanica R. Br. 22:525 Leucetta chagosensis 17:17 Leucetta microraphis 25:705 Leucettamine A 25:705 tert-Leucine 21:297 Leucine 21:738;23:97;25:331 Leucine aminopeptidase 12:434;25:375 Leucine aminopeptidase A 12:434 Leucine rich repeat (LRR.) domain 25:398,402 Leucine-enkephalin (L-ENK) 27:798 Leucocyclusformosus 10:151 ;21:378 Leucodopachrome 16:614 Leucodrin 4:712 Leucogyrophana 29:271 Leucojum aestivum 20:359 Leucojum vernum 20:359
Leucomelone 29:299 synthesis of 29:299 Leucomitomycin C 13:436 Leucomycin A3 5:611,612 Leucomycins 11:164 Leuconitis eugenifolia A. 29:362 Leuconolide A~ 11:163,170 Leuconolide A3 11:163,170 Leuconolides 11:160,163-172 stereoselective synthesis of 11:163-172 Leuconostoc measenteroides 2:350,314, 325;7:69 Leuconotis 29:363 Leucopaxillus albissimus 26:493 Leucopaxilus cerealis var. piceina 21:190 Leucophaea maderae 9:488,489 Leucoquinazirine 4:351 Leucosceptoside 27:837 Leucotriene B4 10:168 synthesis of 10:168 (+)-Leucoxylonine 16:505 Leudrin 4:712 Leu-enkephalin 27:802,803 Leukamenin E 15:175 from Rabdosia umbrosa var. latifolia 15:175 Leukemia 1:275 P-388Leukemia 24:190 Leukemia cells 23:74,186 cytotoxic activity against 23:78, 172,177,180,186,234,649,679, 797,800 ofherbimycin A 23:72,74,90 Leukemia HL-60 cells 21:636 Leukemia P-388 19:558;25:760 Leukocyte activity 26:510 Leukocyte degranulation 30:70 inhibitory action on 30:70 Leukocytes 22:112,437;30:59,60,64,66, 67,70 effect of carp oil on 30:66 effect of oleic acid on 30:65 effect of triterpenoid fraction on 30:60 in LLC-bearing mice 30:59,64 inhibitory action on 30:70 Leukocytopenia 26:243
472 Leukoencephalmalacia 9:215 Leukopenia 5:135;25:431 Leukotriene B4 25:275,617,815,939; 30:70 qinhibitory action on 30:70 Leukotriene B4 production 25:615 Leukotriene B3 10:159,12:399 synthesis of 10:159,12:399 Leukotriene B4 receptor 25:705 Leukotriene biosynthesis 30:225 inhibition of 30:225 Leukotrienes 1:528;5:513,9:368,559, 560;17:642;22:126,434,437;25:274, 275,939-940;30:192,225 and macrophages 30:192 as pain mediator 30:192 biosynthesis of 9:562,576 from arachadonic acid 30:225 LTC4 type of 30:225 LTD4 type of 30:225 LTE4 type of 30:225 peptidoleukotrienes type of 30:225 role in allergy processes 30:225 role in inflammation 30:225 semi-synthesis of 17:642 Leuocylus formosus 24:686,689 Leurocristine 13:655 from Catharanthus roseus 13:655 Leurosidine 14:813,840-846 enantioseletive synthesis of 14:840-846 from anhydrovinblastine 14:871 oxidation of 14:813 3'-oxoleurosidine from 14:813 Leurosine 14:820,821 biosynthesis of 14:820,821 cleavamine from 14:862,863 conversion to anhydrovinblastine 5:186,189 deacetylvindoline from 14:862, 863 20'-deoxyvinblastine from 14:863,864 Na-demethyl-Na-formylleurosine from 14:818,819 from anhydrovinblastine 14:820, 821,871,872
from Catharanthus roseus 14:859 from 15[3,20[3-epoxydihydrocatharanthine 14:871,872 from leurosine N-oxide 14:864 (15'R)- 15'-hydroxycatharinine 14:813,814 oxidation of 14:813,814 3'-oxoleurosine from 14:813,814 21'-oxoleurosine from 14:813, 814 synthesis of 14:811 vinblastine from 14:860 Leurosine N-oxide 14:864 leurosine from 14:864 Leurosinone 5:144-146 Leuteoline 22:423 Leutiginoside alkaloid 27:251 structure of 27:251 Levamisole 26:440,454,485 Levansucrase 8:353 from Bacillus subtilis 8:353 Levisticum 29:581,582 Levoglucosan 12:44,45 c~-methyl aldehyde from 12:45 Levoglucosenone 14:267,276,277 (-)-allo-yohimbane from 14;267, 276,277 (-)-eldar ~ide from 14:272,273 (-)-trans-cognac lactone from 14:272,273 (-)-trans-whisky lactone from 14:272,273 (-)-6-multistriatin from 14:273, 274 (+)-multistriatin from 14:267 (S)- 5-hydroxy- 2-penten-4-o lide from 14:273,274 cycloaddition of 14:270,271 from D-galactose 14:267 Michael addition reaction of 14:271,272 oligomerization of 14:271,272, 274 Prelog-Djerassi lactonic acid from 14:267 preparation of 14:268 purpurosamine C from 14:268
473 reaction of carbonyl group 14:268,269 reaction of double bond 14:269, 270 reserpine from 14:267 serricornin from 14:267,275 synthesis of 14:267,268 tetrodotoxin from 14:267,276, 277 Lbvy and co-workers 29:373,401 rhazinilam synthesis by 29:373, 401 Lew and Kim 29:488 thiocarbapyranoses synthesis by 29:488 Lewis acid catalysis 11:446-451 Lewis lung carcinoma 19:609;30:59 in vitro 30:59 Lexitropsins 5:567,578 Ley synthesis 12:22-24 ofavermectin Bla 12:22-24 Ley's procedure 6:13 in (+)-polygodial synthesis 6:13 Leyssera guaphaloides 25:250 LIA-0788 21:414 Liangshanin A 15:114 n3C-NMR of 15:128 from Rabdosia liangshanica 15:172 ~H-NMR of 15:121 Liangshanin B 15:114 Liangshanin C 15:114 Liangshanin D 15:115 from Rabdosia liangshanica 15:172 nH-NMR of 15:122 Liangshanin E 15:115 n3C-NMR of 15:129 from Rabdosia liangshanica 15:172 IH-NMR of 15:122 Liangshanin F 15:116 t3C-NMR of 15:129 from Rabdosia liangshanica 15:172 ~H-NMR of 15:123 Liangshanin G 15:114 X3C-NMR of 15:128 from Rabdosia liangshanica
15:172 IH-NMR of 15:121 Liatris cylindracea 24:103 Liatris platylepis 24:103 Libinia emarginata 1:704 juvenile hormone from 1:704 Libium maximowiczii 25:788 Libocedrus bidwilli 26:231 Licania apetala vat. apetala 28:41,58 Licania carii 28:38,40-42,60 betulinic acid from 28:42 2ot-hydroxyursolic acid from 28:42 maslinic acid from 28:42 myricetin 3'-methyl-3-Orutinoside from 28:42 myricetin 3-O-(2"-O-fS-Dxylop yrano syl )-cx-L-rha mn opyranoside from 28:42 myricetin 3-O-rutinoside from 28:42 myricetin 3-O-f3-Dgalactopyranoside from 28:42 myricetin 3-O-~-Dglucopyranoside from 28:42 phytochemical studies of 28:38 quercetin 3-O-(2"-O-~-Dxylopyranosyl)-c~-Lrhamnopyranoside from 28:42 quercetin 3-O-rutinoside from 28:42 quercetin 3-O-~-Dgalactopyranoside from 28:42 quercetin 3-O-~-Dglucopyranoside from 28:42 p-sitosterol 3-O-fS-Dglucupyranoside from 28:42 ursolic acid from 28:42 Licania densiflora 28:38,49 3',4'-dimethylmyricetin-3-O-[3D-glucopyranoside from 28:49 myricetin 3 ',5'-dimethylether-3O-cx-L-rhamnoside from 28:49 myricetin 3 ',5'-dimethylether-3O-[3-D-glucopyranoside from 28:49 myricetin 3'-methylether-3-O-13D-galactopyranoside from
474 28:49 myricetin 3-O-( 2"-O-ct-Lrhamnopyranosyl)-ec-Lrhamnopyranoside from 28:49 myricetin 4'-methylether-3-O-etL-rhamnopyranoside from 28:49 naringenin 8-hydroxy-4'-methyl ether from 28:49 phytochemical studies of 28:38 Licania genus 28:35,65 biological studies on 28:35 Licania heteromorpha 28:65 Licania heteromorpha var. heteromorpha 28:38,40,53, 62 alphitolic acid from 28:53 betulinic acid from 28:53 myricetin 3,4'-di-O-ct-Lrhamnopyranoside from 28:53 myricetin 3-O-ct-Lrhamnopyranoside from 28:53 myricetin 3-O-~-Dgalactopyranoside from 28:53 myricetin 4'-methylether-3-O-ctL-rhamnopyranoside from 28:53 myricetin 4'-methylether-3-O-[3D-galactopyranoside from 28:53 myricetin 4'-methylether-3-O-13D-glucopyranoside from 28:53 myricetin 7-methylether 3,4'-diO-c~-L-rhamnopyranoside from 28:53 3 f3-O-cis-p-coumaro yl alphitolic acid from 28:53 3 ~-O-cis-p-coumaro yl maslinic acid from 28:53 3 ~-O-cis-p- coumaroyl-2 c~hydroxy-urs- 12-en-28-oic acid from 28:53 3 ~-O-trans-p-coumaro yl alphitolic acid from 28:53 3 ~-O-trans-p-coumaro yl maslinic acid from 28:53 3 f3-O-trans-p- coumaro yl-2 ahydroxy-urs- 12-en-28-oic acid
from 28:53 phytochemical studies of 28:38 Licania heteromorpha var. heteromorpha 28:62 anti-microbial activity of 28:62 Licania intrapetiolaris 28:38 cucurbitacin B from 28:59 intrapetacin A from 28:59 intrapetacin B from 28:59 phytochemical studies of 28:38 Licania licaniaeflora 28:38,40,56,63 anti-oxidant activity of 28:63 arjunic acid 28-D-D-glucosyl ester from 28:57 betulinic acid from 28:57 maslinic acid from 28:57 olean- 12-ene-2c~,3[3-diol from 28:57 oleanolic acid 3-O-~-Larabinopyranoside from 28:57 oleanolic acid from 28:57 pomolic acid from 28:57 phytochemical studies on 28:38 tormentic acid 28-[3-D-glucosyl ester from 28:57 ursolic acid from 28:57 Licania michauxii 28:65 Licania pittieri 28:38,42,60 catechin from 28:42 epicatechin from 28:42 phytochemical studies of 28:38 quercetin from 28:42 quercetin 3-O-ct-Larabinopyranoside from 28:42 quercetin 3-O-c~-Lrhanmopyranoside from 28:42 quercetin 3-O-fS-Dgalactopyranoside from 28:42 quercetin 3-O-[5-Dglucopyranoside from 28:42 ursolic acid from 28:42 Licania pyrifolia 28:38,40,42 ct-amyrin from 28:42 betulin from 28:42 betulinic acid from 28:44 2,3-dihydroxylup- 12-en-28-oic acid 3-(3 ',4'-dihydroxy-benzoyl ester) from 28:44,45
475
2a,3 c~-dihydroxyurs- 12-ene-28oic acid from 28:45 euscaphic acid 28-[3-Dglucopyranosyl ester from 28:45 euscaphic acid from 28:45 11c~-hydroxybetulinic acid from 28:44 613-hydroxybetulinic acid from 28:44 2c~-hydroxyursolic acid from 28:45 lupeol from 28:42 maslinic acid from 28:45 oleanolic acid from 28:44 phytochemical studies of 28:38 13-sitosterol 3-O-[3-Dglucopyranoside from 28:45 [3-sitosterol from 28:42 tormentic acid 28-[3-Dglucopyranosyl ester from 28:45 tormentic acid from 28:45 2,3,27-trihydroxylup- 12-en-28oic acid 3-(3 '-4'-dihydroxybenzoyl ester) from 28:45 ursolic acid 3-O-a-Larabinopyranoside from 28:45 ursolic acid from 28:44 uvaol from 28:44 Licaria puchury 22:525 Licarin A 26:247 Licarin B 26:858 Licarin C 26:202 Licarin D 26:247 Lichenan 5:309-311,322 Lichenan polysaccharide (PS) 30:412 from moss 30:412 Lichens 9:317,328 LiC104 8:166,167 as supporting electrolyte 8:166, 167 Licochalcone 21:740-744 bioactivity of 21:744 synthesis of 21:741-743 Licochalcone A 26:800,801 ;28:224 anti-Helicobacter pylori activity of 28:241
anti-microbial activity of 28:224 biological activity of 28:229 Licochalcone B 28:226 anti-human immunodeficiency virus (HIV) activity of 28:226 anti-Helicobacter pylori activity of 28:241 anti-microbial activity of 28:224 biological activity of 28:229 Licochalcones A and B 27:425 structure of 27:427,428 Licoflavonol 28:229 biological activity of 28:229 Licohalcone A 21:742,743,744 Licoisoflavanone 28:229 biological activity of 28:229 Licoisoflavone 4:378,383 synthesis of 4:378,383 Licoisoflavone A 28:229 biological activity of 28:229 Licoisoflavone B 28:224 anti-Helicobacter pylori activity of 28:241 anti-microbial activity of 28:224 biological activity of 28:229 ~,-Licorane 3:431 synthesis of 3:431 Licorice 21:740;26:745;28:204,205 anti-hepatitic principles from 28:205 antitussives from 28:205 anti-ulcer compounds from 28:205 dihydrophenanthrene from 28:205 dihydrostilbenes from 28:205 flavor from 28:205 isoliquiritigenin from 28:205 isoliquiritin from 28:205 liquiritigenin glycosides from 28:205 liquiritin apioside from 28:205 liquiritin from 28:205 sweetening agents from 28:205 Licorice flavonoids 28:224 anti-Helicobacter pylori activity of 28:234 anti-microbial activity of 28:62, 224,257,293
476 Licorice root 22:422 Licorice-saponin 28:241 anti-Helicobacter pylori activity of 28:241 Licoricidin 28:241 anti-Helicobacter pylori activity of 28:241 anti-microbial activity of 28:62,224,257,293 biological activity of 28:229 Licoricone 4:378,383;28:224 anti-Helicobacter pylori activity of 28:243 anti-microbial activity of 28:224 biological activity of 28:229 synthesis of 4:378,383 Licorisoflavan A 28:229 biological activity of 28:229 Lienomycin 6:261 relative configuration of 6:251 Liensinine 21:79 Ligand 30:799,808 opioid receptivity of 30:808 Ligand-gated channel 21:11,14,20 Ligand-gated ion channel 25:527 neurotransmitter receptor 25:527 Ligand-receptor interactions 19:240 Ligase 17:480 Light 2:155,156 circularly polarized 2:154 interactions with molecules 2:155,156 linearly polarized 2:153 Light scanning detection (LSD) 18:195 Liginine 25:126 Ligistrum 26:327 Lignan constituents 30:588 against cancer cell lines 30:588 Lignan podophyllotoxin 13:654 Lignans 5:9,459,503,753,754,311; 17:313,441 ;20:108-113,273,613; 24:215,228-232,503-509,739-798; 26:229,790,813,887 ;30:560,562,567, 570,590,594 ;24:215,228-232,739798;26:206,207 antileishmanial activity of 26:229,790,813,887 antiperoxidative effects of 26:249-255
antiplatelet aggregation due to 30:560 as antiviral compound 24:503-509 as phytoestrogens 26:206,207 biological activity of 5:505,544, 545;24:739 cytotoxicity due to 30:560 Epstein-Barr virus inhibition due to 30:560 from Abies sachalinesis 20:613-620 from Hernandia ovigera 18:551 from Salix sachalinensis 20:627 parasiticidal activity of 26:229 synthesis of 18:551;24:739 transformations of 24:739 turbidimetry assay 30:594 Lignarenones A,B 10:152,167,171 synthesis of 10:167,171 Lignicolous fungi 22:69,74,72 Lignin 5:309-311,322,461-463,467, 472;26:1262 Lignin polymer 27:760 Lignincola laenis 25:899 Lignothioglycolic acid 25:668 Ligstroside 26:318,333,334,343 Ligularia fischeri 29:87 Ligularone 4:615 synthesis of 4:615 Liliaceae 6:487;7:427;17:130;21:129, 644,668,673,674 saponin from 21:643 Lilium candidum 21:128 lilaline from 21:128 Lilium longifolium 18:507;21:643; 25:391 teasterone myristate from 18:507 teasterone 3-myristate from 18:495,522 Lilium nobilissimum 21:643 Lilium speciosum 21:643 Lillium candidum 21:128 Lillium maximowezii 23:341 Limatine 1:40 Limatinine 1:40 Limatulone 17:26,27
477
Limbic brain regions 30:383 serotonin (5-HT) receptors in 30:383 Limbinol 20:683 from Salvia limbata 20:683 Li-methylsulfynil carbanion 27:512 Limettin 23:352 Limnocorrals 26:381 Limnophila chinensis 22:525 as antispasmodic 22:525 Limocin A 9:300,302,303 Limocin B 9:300,302,303 Limocinin 9:300,304,305 Limocinol (tirucalla-7,24-dien 1613-ol) 9:300,301 Limocinone 9:300-303 Limocitrin rhamnoside 25:594 Limocrocine 21:374,405,407 Limonen 20:6,13,16 Limonen- 1,2-oxide 29:83 activity in lung-1, RAS bioassay system 29:83 (+)-Limonene 5:702;10:412;15:257; 21:585;27:372 Nazarov cyclization of 10:412 (-)-Limonene 16:211,216;21:585 Limonene 16:211,221,260;20:6,13,16; 21:574,599,600,607,614 ;25:44,125, 133,140,145-147,149,150,15130:723 structure of 30:723 (d)-Limonene 21:585,618,621 8-Limonene 23:818 d-Limonene 27:386;29:83 activity in AM assay system 29:83 activity in GPx assay system 29:83 activity in GST assay system 29:83 activity in NFkB assay system 29:83 activity in RAS assay system 29:83 activity in mam-1 assay system 29:83 activity in mam-2 assay system 29:83 activity in stoma assay system 29:83
activity in AM assay system 29:83 activity in TPA assay system 29:83 activity in liver-1 assay system 29:83 activity in lung-1 assay system 29:83 activity in AM assay system 29:83 R-(+)-Limonene 5:732,733;8:48;16:208 S-(-)-Limonene 6:74,75;16:208,225 (-)-pseudopterosin A from 6:74, 75 (+)-Limonene oxide 19:205 Limonene- 1,2-diol 29:83 activity in RAS assay system 29:83 Limonene- 1,2-epoxide 25:150 Limonene- 1,2-epoxide hydrolase 25:150 Limonene- 1,2-oxide 16:208,217 (+)-Limonene-l,2-(-)trans-diol 25:147, 150 Limonia acidissima L. 20:497;22:525 for epilepsy 22:525 Limonia crenulata 22:525 for epilepsy 22:525 Limonin 9:307 D-seco-Limonoids 26:815 Limonoids 9:307,20:492;22:146 from Trichilia emetica 20:492 Linalool 13:332;20:587;21:589,600, 602,607,612,615;22:509,511,537; 25:125,136,140,142,162;26:396,397; 28:406,413;29:83 acaricidal activity of 28:412 acaricidal properties of 28:406 activity in RAS assay system 29:83 activity in TPA assay system 29:83 analysis of 28:413 epoxide of 26:397 O-Linalool 25:141,147 (R)-(-)-Linalool 25:143 (+)-Linalool 27:384 Linalool enantiomers 27:379 Linalool epoxide 25:143
478 Linalool-8-carboxylic acid 25:141 Linalyl acetate 17:604;25:136,140,141; 27:374 structure of 27:374 (-)-(3R)-Linalyl diphosphate 11:220 Linaria saxatilis var.glutinosa 29:689 Linarioside 7:440 Linckia guildingi 7:298 Linckia laevigata 7:290,295,46,61 laevigatoside from 7:290 maculatoside from 7:290 marthasteroside A1 from 7:290 ophidianoside F from 7:290 thornasteroside A from 7:290 Lincomycin 1:429 Lincosamine 11:429 and galacto configuration 4:147, 148 by [4+2] cycloaddition 4:145 from D-threonine 4:140-143, 145,147,148,: 140,141 synthesis of 4:140-143,145,147, 148 Lincosamine derivative 4:145 by cis-hydroxylation 4:145 Lindbladia tubulina 29:254 Lindelofine 1:267 synthesis of 1:267 Lindera umbellata 28:419 Linderazulene 5:368,369;14:315 Lindlar catalyst 6:79,157,559;19:42,594 triple bond reduction 4:532 Linear conformation 11:115 of polyketide 11:115 Linear diterpene 24:282 Linear triquinane 13:34-46 synthesis of 3:14 Linearly polarized light 2:154 Linearol 29:100 activity in NFkB bioassay system 29:100 Lineus fuscoviridis 18:725 Lingbya majuscula 25:876,902 a-Linked 3'-deoxycyclitol 14:147 synthesis of 14:147 13-(1~ 1)-Linked 4,4'-dithiotrisaccharides 8:344-346 synthesis of 8:344-346
[3 (1-~6)-Linked 6-thiodissacharides 8:339 synthesis of 8:339 [3-(1-6)-Linked disaccharides 6:395, 396,403 fl, l-Linked galactose 25:295,316 c~-D-Linked glucans 5:288 Linked scan mass spectra 2:43 1-~2-Linked thiodisaccharides 8:327, 328 synthesis of 8:327,328 1-+3-Linked thiodisaccharides 8:329 synthesis of 8:329 1--~4-Linked thiodisaccharides 8:329-337 1--~6-Linked thiodisaccharides 8:340 1--~6-Linked thiosaccharides 8:338-340 S-Linked thiotrisaccharides 8:340 Linkiol 5:725,727 Linkitriol 5:725,727 p-methoxybenzoate of 5:725,727 Linoleic acid 13:304,305,311,313,659; 21:187,189;22:317;26:361,433,434, 461;27:68;30:65 from carp oil 30:65 lipid peroxidation of 27:59,68, 85,504,505 Linoleic acid (9,12Z)-octadecadienoic acid 9:560-563,565-567,573-575, 581 8-Linolenic acid 26:361 Linolenic acid 23:342;27:70 generation of 16S-hydroperoxy9Z, 12Z, 14E-octa-decatrienoic acid (16S-HPOTE) from 27:70 generation of 9S-hydroperoxy10E, 12Z, 16Z-octadecatrienoic acid from 27:70,71 Linolenic methyl ester 2:11 Linone-l,2-diol 25:146 Linonene epoxide 25:146,147 Lintenolide F & G 25:700 Linum 26:172,173 Linum album 26:173 Linum flavum 26:173,212 5-methoxypodophyllotoxin from 26:212
479 Linum usitatissimum L. 22:525;26:206;
29:608 for hysteria 22:525 Lipase P 1:687,19:153 Lipase PS 16:703 Lipases 13:9,14;24:1005;27:66 enzymatic activity 24:1005 Lipasic enzymatic activity 24:999-1001 Lipid A 28:518,519,523,525,526, 529,534,537,538 acute effects of 28:523 antitumor activities of 28:518 association with immunomodulators 28:534 biological properties of 28:519 effect on acquired immunity 28:529 effect on cytokine production 28:526 effect on innate immunity 28:525 in cancer vaccination 28:537 to treat tumor-bearing animals 28:538 treatment with 28:534 Lipid A DT 5461 28:534 for C38 colon carcinoma 28:535 for Lewis lung carcinoma 28:535 for MH134 hepatoma 28:535 for MM46 mammary carcinoma 28:535 for murine Meth A fibrosarcoma 28:535 treatment with 28:534 Lipid A OM-174 28:536 antitumor activity of 28:536 treatment with 28:536 Lipid A ONO-4007 28:535 treatment with 28:535 Lipid A tolerance 28:521 by anti-LPS antibodies 28:522 Lipid disorders 5:695 Lipid hydroperoxides (LOOHs) 27:59, 67,68, 73,78 degradation products of 27:68 Lipid oxidation 23:767 measurment of 23:768 Lipid oxidation system 23:773
Lipid peroxidation 4:495;27:59,68,85, 504,505 inhibitor of 4:495 oflinoleic acid 27:68 relation with apoptosis 27:86-88 Lipid peroxidation activity 26:253 Lipid peroxidation products 27:84-86 in biological materials 27:84-86 relation with cell death 27:86-88 Lipid storage disease (phytoesterolemia) 9:478 Lipid-diphosphooligo-saccharide 26:1131 Lipid-linked high-mannose oligosaccharide (IV) 10:499 Lipids 24:1009-1015,1050;28:517; 29:233 anti-rumor activity of 28:517 absolute structures of 29:233 lycogarides as 29:233 total fatty acids of 24:1009-1015 triglyceride of 24:1009-1015; 29:233 Lipid-soluble antioxidant 30:322 uniquinone as 30:322 Lipitor atorvastatin 22:252 Lipo-CCK 18:844-848 biological properties of 18:857-863 physical properties of 18:844-848 biological properties of 18:857-863 Lipo-gastrin 18:844-848 biological properties of 18:844848 physical properties of 18:844848 Lipogenesis 27:393 biological activity of 27:393 insulin-induced 27:397 Lipohilicity 15:355 R(+)-ot-Lipoic acid 1:536-538 synthesis of 1:536-538 Lipoic acid 1:600,602 synthesis of 1:600,602 Lipolysis 27:393 biological activity of 27:393
480 Lipolytic action 27:394 activity of 27:394 Lipolytic activity 23:364 of coumarin 23:335,356,357, 353,3 68,376,393,550,553 Lipomannan 26:1155 [3-Lipomycin 28:135 as antibacterial agent 28:135 c~-Lipomycin 28:135 as antibacterial agent 28:135 Lipooxygenase pathway 25:263 Lipooxygenases 25:597,939,940 Lipopeptidophosphoglycan (LPPG) 2:302-309 Lipoperoxidation assay 25:940 Lipoperoxidation process 25:614 Lipophilic antioxidant 30:224 design of 30:224 Lipophilic derivatives 18:840-851 Lipophilicity 4:369 Lipophosphoglycan (LPG) 2:312 from Leishmania donovani 2:312 Lipopolysaccharides (LPS) 25:477,460; 26:597,951,1152;27:856;28:518,520, 521,523,528,533,539;30:420 acute effects of 28:523 antigenic properties of 28:518 biological properties of 28:518 by PROb colon cancer cells 28:533 components of 30:420 effects on angiogenesis 28:528 effects on blood flow 28:528 in human macrophages 28:521 in peritoneal carcinomatosis 28:533 of gram-negative bacteria 30:420 phase I trials with 28:539 receptor for 28:520 role in immunospecificity 30:420 Lipoxins 9:559 biosynthesis of 9:561,575-578 Lipoxygenase 5:521,559-589;13:303, 305,311;21:134 12-Lipoxygenase 25:47 inhibition of 25:47
15-Lipoxygenase 25:47 inhibition of 25:47 5-Lipoxygenase 5:513,514,820;25:47; 30:225 inhibition of 25:47 redox inhibitors of 30:225 Lipoxygenase catalysis 9:559-589 products of 9:559-589 substrate of 9:559-589 5-Lipoxygenase inhibition 30:225 effect of polyhydroxylated 2phenylnaphthalenes 30:225 effect of tetrahydroxypavinan 30:225 5-Lipoxygenase inhibitor 28:215; 30:226 artonin E as 28:201,215 IC50 values of 30:226 5-Lipoxygenase inhibitory activity 2:282,284,335;24:855 of Magnolia liliflora 24:855 Lipoxygenases 27:59,67-69,88 from soybean 27:69,70 of tomatoes 27:70 Lipoxygenation 9:573 oflinoleic acid 13:311 R-Lipoxygenation 9:574,575 Lipozyme activity 20:845 Lippa dulcis Trev. 24:799;27:13,21 (+)-hernandulcin from 27:13,21 4[3-hydroxyheman dulcin from 27:13,21 Lippia alba 21:617 Lippia dauensis 21:595 Lippia grandifolia 21:595 Lippia javanica 21:595 Lippia multiflora 21:613 Lippia nodiflora 5:647,648,655 Lippia somalensis 21:595 Lippia sp. 7:427 Lippia ukambensis 21:595 Lippia wilmsii 21:595 Lipria dulcis 15:14 Liquid chromatography 21:579 Liquid chromatography-mass spectrometry 21:555 Liquid secondary ion mass spectrometry (LIMS) 2:20
481
dispersing matrices 2:20 effect of salts 2:24 of bovine insulin 2:23-25 of methionyl-enkephalin 2:21-23 of peptides 2:20-30 spectrometry (LIMS) 2:20-41 Liquid secondary ionization LSI MS 9:487 Liquid sodium amalgam 11:371 Liquid sodium-potassium alloy 11:371 Liquidamber formosana 23:405 Liquid-Liquid extraction 21:526,527 Liquiritigenin 26:745;28:241 anti-Helicobacter pylori activity of 28:241 anti-microbial activity of 28:224 Liquiritin 28:241 anti-Helicobacter pylori activity of 28:241 anti-microbial activity of 28:224 Liquiritoside 22:423 Lirinidine 21:68,73;22:22 Liriodendrin 26:233 Liriodendron tulipifera 5:476 Liriodenine 2:435-439;9:396,398, 20:483 activity in 2:435,437,439 Lirioresinolglycoside 26:268 13-dimethyl ether of 26:233,268 (-)-Liriorinol B 26:229 Lirodendrin 5:475,476 Lisianthoside 7:443 Lissochinotoxin A 23:236 Lissoclin C 23:263 Lissoclin disulfoxide 25:834,863 Lissoclinamide 1 25:880 Lissoclinamide 2 25:880 Lissoclinamide 3 25:880 Lissoclinamide 4 25:880 Lissoclinamide 5 25:880 Lissoclinamide 6 25:880 Lissoclinamide 7 25:880 Lissoclinamides (1-5) 10:242,243 Lissoclinium patella 25:879,880 Lissoclinotoxins 23:236 Lissoclinotoxin A 10:244;25:834 Lissoclinotoxin B 25:835
Lissoclinotoxin C 23:237;25:835 tris(methylthio) derivatives 25:835 Lissoclinotoxin D 23:237;25:833,835 Lissoclins 25:821 Lissoclinum 25:707,821,833,834,862, 878 Lissoclinum bistratum 10:243;25:881, 882;28:628 bistratamide A from 28:628 bistratamide B from 28:628 bistratamide C from 28:628 bistratamide D from 28:628 Lissoclinum fragile 23:262;25:782 Lissoclinum genus 25:833 Lissoclinumjaponicum 25:833;28:637 dimethyl-5-(methylthio) varaein from 28:637 Lissoclinum lisschlinotoxin A 25:833 Lissoclinum patella 4:89,93,99;5:419, 420;10:242,243 ;25:878,891; 28:622-629 ascidiacyclamide from 28:622 heptapeptide ulicyclamide from 28:622 patellamide A from 28:623 patellamide B from 28:623 patellamide C from 28:623 patellamide E from 28:627 patellamide F from 28:627 patellamide G from 28:627 patellazole A from 28:625 patellazole B from 28:625 patellazole C from 28:625 patellins 1-6 from 28:629 prepatellamide A from 28:626 tawicyclamide A from 28:629 tawicyclamide B from 28:629 trunkamide A from 28:629 ulithiacyclamide from 28:622 ulithiacyclamide B from 28:623 Lissoclinum perforatum 10:244;23:236; 25:833;28:636 1,2,3-trithiane derivative from 28:636 Lissoclinum sp. 28:636 lissoclinotoxin A from 28:636 lissoclinotoxin C from 28:636
482
lissoclinotoxin D from 28:636 trithiane from 28:637 Lissoclinum tunicate 28:715 Lissoclinum vareau 10:243;23:236; 25:871,833 varacin from 28:637 varamine A from 28:638 Lissoclinum voeltakowi Michaelson 25:269 Lissodendoryx isodactyalis 5:395, 13:168;18:715,716 Lissodinum 25:833,834 (-)-Listenolide C~ and C2 16:698-699 Listera ovata 26:1135 Listeria infection 25:431 ;30:766,768 host defense against 30:766 late phase of 30:769 protective mechanism against 30:766 stage of 30:768 with LP-BM5 MuLV 30:766 with murine leukemia viruses 30:766 Listeria monocytogenes 21:618;27:381; 30:766,767,773 host defense against 30:766 in immune response 30:773 Listeria-specific antigens 30:770 Listeria-specific cell-mediated immunity 25:431;30:768 development of 30:768 Litalin flavonoids 26:744 Lithiated 2-acetylthiazole 30:437 Lithiated trimethylsilylacetonitrile 1:311,312 Lithiation 5:827 of 2-methoxy-N, N-diethylbenzamide 5:827 of 3-methoxy-N, N-dimethylbenzylamine 5:828,829 with sec-butyllithium 5:827,828 1-Lithio glycals 10:345 by direct lithiation 10:345 from tributyltin 10:345 2-Lithio-2-phenyl-6-heptene 8:7,8 synthesis of 8:7,8 2-Lithio-3,3-diethoxy- 1-propene 12:36, 40,43
Lithiodianion-imine condensation 4:433,443-448,450,464 2-Lithiofuran 30:469 addition of 30:469 Lithioglycal 10:346 N-Lithioimidazolidines 1:349-351 anionic cycloreversion of 1:349-351 2-azaallyl anions from 1:349-351 Lithistid sponges 26:1175,1176 Lithistida 28:658 Lithium/4,4'-di (tert. butyl) biphenyl (DTBBP) 11:309 Lithium 2-thienylcyanocuprate 21:393 Lithium aluminium hydride 22:288,293 Lithium di (c~-ethoxyvinyl) cuprate addition of 12:25 BF3 OEt2 promoted 12:25 to m 2'3 e n o n e 12:25 (E)-Lithium enolate 30:25,469 oxidation of 30:469 Lithium hexamethydisilazide (LHMDS) 24:9,10 Lithium isopropylcyclohexylamide (LICA) 10:410 Lithium methylcrotyl aluminate 6:298, 299 condensation with 6:298,299 Lithium organocuprates 4:555,556 1,4-addition 4:555,556 Lithium organyls 4:556-558 1,2-addition 4:556-558 Lithium triethyl borohydride 11:423 reduction with 11:83,84 Lithium tri-sec butylborohydride (Lselectride) 11:234 Lithocholic acid 27:858,859 Litholytic properties 26:52,54 of Herniariafontanesii 26:52,54 Lithontriptic 20:79 Lithospermic acid A 30:227 as HIV-1 integrase inhibitors 30:227 structure of 30:227 Lithospermic acid B 30:227 as HIV- 1 integrase inhibitors 30:227 structure of 30:227
483
Lithospermic acids 30:226 effect on HIV-1 infected H9 cells 30:226 Lithospermum 22:76 Lithospermum erythrorhizon 7:88; 30:345 BK-39 callus culture of 30:345 shikonin from 7:88 Lithramine 20:276 L-itronellol 25:125 Litsea cubeha 25:132 Litsea odorifer 24:275 Littorine 17:397;21:56;22:728 Lituaria australasiae 19:596 Lituarines A-C 19:596 Liu-Kulkarni synthesis 6:43,44 Liver 30:64 metastasis in 30:64 Liver cancer 20:528 Liver carcinoma 30:406 Liver disorders 30:637 role of oleanolic acids in 30:637 Liver hepatocytes 30:406 Liver injury 25:461 ;30:637 effect of LPS toxicity on 25:461 effect of TNF-a 25:470 role of oleanolic acids in 30:637 Liver insufficiency 26:1130 as syndrome type-lA 26:1130 Liver intoxication 25:459-462 with D-Gal N/LPS 25:459-461 with D-gal N/TNF-a 25:460,461 Liver metastatic tumor colonies 30:66 effect of oleic acid on 30:65 Liver necrosis 30:406 Liver tumor model (H22) 30:841 effect of Eisenia fetida 30:841 Liver-derived NO 25:471 Liverwort sesquiterpenoids 18:607-646 absolute configuration of 18:607-646 Liverworts 1:719,81,273,277-290 Livestock 30:751 toxic disease 30:751 Lividomycin A 14:186 Lividomycin B 14:145,186 L-Lividosamine 14:144 D-Lividosamine 14:144,186-193 synthesis of 14:186-193
LLC cells 30:65 intrasplenic implantation of 30:65 LLC cells DNA synthesis 30:67,68 effect of oleic acid on 30:67,68 LLC tumor metastasis 30:60 effect of triterpenoid fraction on 30:60 inhibition of 30:60 LLC-bearing mice 30:59,61 leukocytes in 30:59 tumor in 30:61 llludane-dienone 26:716 LL-Z1271a 28:473,495 anti-fungal activity of 28:473 synthesis of 28:495 L-malic acid 30:38,39 (2S,3S)-2-ethyl-3,4-isopropylidene dioxypropan-l-ol from 30:39 role in (-)-pironetin synthesis 30:38 L-norepinephrine 25:530 lnositol-l,3,4,5-tetraphosphate acid 25:516 LO" radicals 27:78,79 generation of 27:78 Lobane diterpenes 21:276 Lobaria retigera 13:22 (-)-retigeranic acid from 13:22 Lobatetraene 21:276 3,4-Lobatin 26:808 Lobatin A&B 26:808,809 Lobatoside B-E 21:634 Lobatosides 15:191 Lobatrienediol 21:276,277 Lobelia inflata L. 22:525;29:583 for epilepsy, hysteria and convulsions 22:525 Lobeline 21:96,97,102,109,108 (-)-Lobeline 22:17 c~-Lobeline 27:283 (7E)-Lobohedleolide 10:13,14 Lobohedleolide 8:15,14,5,13,14 inhibition of hela cells growth 8:16 ofhela cells 8:16 Lobophylum crassum 8:11 isolobophytolide from 8:20
484
Lobophytum pauciflorum 21:276 Lobophytum sp. 21:276 Lochneram 13:387 Lochnericine 2:375 20-epi-Lochneridine 1:32,127 Lochneridine 1:36;5:172 Lochnerine 9:174,386,429 Loco syndrome 7:71 Locois 27:523 Locomotor activity 21:749 Locusta 9:489 Locusta migratoria 22:387,398;24:115, 116;29:6 Locusta migratoria manilensis 18:771 Locusta migratoria migratorides 7:395, 18:771 Lodoperoxidase 25:758 Lofentanil 30:200 as morphine analogue 30:200 Loganiaceae 6:520,530 pyrido [4,3B] carbazole alkaloids in 6:507 (+)-Loganin 16:294 synthesis of 16:294 Loganin 6:503,529;7:440,455,470; 20:47 strychonovoine from 6:524 Loganin aglycone silyl ether 16:293 from Strychons nux vomica 16:293 synthesis of 16:293-294 Loganin derivatives 6:524 Loliolide 29:111 activity in EBV bioassay system 29:111 Lolium multiflorum Lam. 27:217 Lolium perenne L. 26:696;27:217 Lollo rosso 23:759 HPLC chromatogram 23:759 Lombardo methylenation 6:209 Lombardo reagent 11:40,41 methylenation with 11:40,41 Lonchocarpus 26:487 Lonchocarpus capassa 29:598 Lonchocarpus minimiflorus 29:782 Lonchocarpus subglauscescens 29:780 Lonchocarpus urucu 28:435
Lonchura malabarica 5:837 hemoglobin components of 5:837 Lonchura malacca 5:837 hemoglobin components of 5:837 Lonchura punctulata 5:837 hemoglobin components of 5:837 Long range heteronuclear COSY spectrum 2:147-151 isomycorhodin 2:150 Long range 13C-1H-COSY spectrum 2:93,95 of 20 (S)-hydroxydammaran-3one 2:39,94 of dendropanoxide 2:100 of marchantin A trimethyl ether 2:107,112 ofsacculaplagin triacetate 2:87 Long range HETCOR 9:147,151,153 Longamide B 25:777,778 Longamides 25:757 Long-chain sugars 14:179 (+)-Longiborneol 4:675 (+)-Longicamphor 4:675 Longicaudatine 26:1051 Longicaudosides A,B 7:309,94 from Ophiderma longicaudum 7:308 Longifolene 4:675;7:110;16:136,608 to isologifolene 4:639 Longifolin 21:361 Longikaurin A 15:138,145 13C-NMR of 15:155 from Rabdosia longituba 15:173 from Rabdosia ternifolia 15:175 ~H-NMR of 15:156 Longikaurin B 15:139 ~3C-NMR of 15:156 from Rabdosia longituba 15:173 ~H-NMR of 15:147 Longikaurin D 15:175 from Rabdosia trichocarpa 15:175 Longikaurin G 15:139 13C-NMR of 15:156 from Rabdosia longituba 15:172 ~H-NMR of 15:147
485
Longilactone 23:301 Longilobol 7:218 from Artemisia longiloba 7:218 Longipinane derivatives 7:218 cis-Longipinane-2,7-dione 27:587 trans-Longipinane-2,7-dione 27:587 Longipinen 8:33,37 synthesis of 8:33,37 Longipinen-7-ol 9:534 NOED spectra of 9:534 c~-Longipinene 8:33,37 synthesis of 8:33,37 [~-Longipinene 8:33,37 synthesis of 8:33,37 (+)-c~-Longipinene 8:37 synthesis of 8:37 (+)-[3-Longipinene 8:37 synthesis of 8:37 Longirabdosin 15:116,123,135,173 from Rabdosia longituba 15:173 ~H-NMR of 15:123 Longispinogein 22:122 Longitin 30:285 1H-NMR spectral data of 30:285 Long-rang 8C/8H COSYspectrum 2:115, 261,263 Long-range ~3C-~H-shift correlation spectrum 5:507 of acteoside 5:507 Long-range C-H couplings 2:115-135 in aromatic compounds 2:115-135 Lonicera fulvotomentosa 21:656 fulvotomentosides from 21:656 Lonicera nigra 7:427 Lonomycin 19:128 Loperamide 30:200 antidiarrheoal activity of 30:200 Lophanthoidin A 15:167,168-170 13C-NMR of 15:170 from Rabdosia lophanthoides 15:173 tH-NMR of 15:169 Lophanthoidin B 15:168-170 13C-NMR of 15:170 from Rabdosia lophanthoides 15:173 ~H-NMR of 15:169
Lophanthoidin C 15:168 from Rabdosia lophanthoides 15:173 IH-NMR of 15:169 Lophanthoidin D 15:168 from Rabdosia lophanthoides 15:173 tH-NMR of 15:169 Lophanthoidin E 15:168-170 13C-NMR of 15:170 from Rabdosia lophanthoides 15:173 ~H-NMR of 15:169 Lophanthoidin F 15:168-170 13C-NMR of 15:170 from Rabdosia lophanthoides 15:173 ~H-NMR of 15:169 Lopharia papyracea 29:265 Lophozozymus pictor 5:393 Loreainide 30:200 antiarrhythmic activity of 30:200 Loropetalin A 23:407 Loropetalin B 23:405 Loropetalum chinense 23:405 Lossen rearrangement 26:1074 Lotus corriculatus 25:93 Lotus uliginous 19:117 Lovastatin 21:211,212;22:255;23:582 LoVo tumor cell 21:165 Low density lipoprotein 27:846 chemical degradation of 27:846 Lowary and Callam 29:457 carbafuranose synthesis by 29:457 Lowry method 25:435 Low-temperature NMR analysis 27:344 Low-valent titanium 4:521-535 from reductive elimination 4:521-535 Low-valent titanium reagent 11:364 keto aldehydes with 11:364 preparation of 11:364 3 [3-H-Lpecoside 26:97 LPLC 7:407,408,410,415,418 antigenic specificity of 4:195 6-deoxy-D-mannoheptose in 4:195 interleukin I induction by 4:197
486
LPS 25:466 hepatic intoxication with 25:466 LPS hepatotoxicity 25:461,462 LPS induced liver injury 25:475 LPS stimulation 25:475 LPS toxicity 25:461 effects on liver injury 25:461 LPS-beated macrophages 25:473 LPS-elicited hepatocyte apoptosis 25:463 LPS-elicited liver injury 25:463 LPS-induced Ca 2§ elevation 25:475 LPS-induced hepatocyte apoptosis 25:463,471 LPS-induced nitric oxide 25:471 LPS-induced TNFa production 25:470 LPS-related liver injury models 25:463 (+)-lsopiperitenone 25:150 [3-1sopropenyl pimelicacid 25:145 10-1sothiocyanato-5-amorphene-4-ol 25:852 (-)- 13-1sothiocyanatocubebane 25:853 (-)- 10-1sothiocyanatokalihinol C 25:852 (-)-9-1sothiocyanatotrachyopsane 25:853 LSPD experiments 2:111 ofmarchantin A 2:108,112 p-Ltalicum 25:145 LTP-blocking effect 25:966 of ethanol 25:966 L-Tryptophan 25:652 L-Tyrosine 25:652 Luaraceae 21:616 Lucenin 2 7:207 Luche reaction 1:474 Luche reduction 14:126,19:372-373 Luche-type reduction 4:130 with (x,13-unsaturated ketone 4:130 Lucidene 751 Lucidin 26:640,657,661,674,675,670 Lucidin glucoside 26:661 Lucidin primeveroside 26:642,662,676 Lucidin 03-ethylether 26:661,676 Lucidin 03-methylether 26:662,676 Lucosceptoside 25:543 Ludalbin 7:232 Ludongnin 15:112
Ludongnin A 15:112,141 13C-NMR of 15:158 from Rabdosia rubescens 15:174 from Rabdosia rubescens var. lushiensis 15:174 IH-NMR of 15:149 Ludongnin B 15:141 13C-NMR of 15:158 from Rabdosia rubescens 15:174 from Rabdosia rubescens vat. lushiensis 15:174 ~H-NMR of 15:149 Ludovicin A 27:553 Ludovicin A-C 7:232 Ludovicin B 27:553 1-epi-Ludovicin C 27:554 Luffa acutangula 29:615 Luffa cylindrica 21:671 ;22:116,120; 29:575,587,615 Luffariella variabilis 17:10;18:717; 21:252;25:696 Luffariellin A and B 18:717 Luffariellin A-D 17:10 Lugrandoside 26:328 Luidia maculata 7:303-306,15:46 luidiaglycosides A-D from 7:288 maculatoside from 7:289 marthasterosides from 7:289 thomasteroside A from 7:289 Luidiaglycosides A-D 7:288,289,293 from Luidia maculata 7:288 Lukes-Sorm dilactam 6:441,442,444 Lukianols 23:242,245 Lumbricus 30:828 from Lumbricidae family 30:828 Lumbricus bimastus 30:827,828 from Lumbricidae family 30:828 Lumbricus castaneus 30:828 from Lumbricidae family 30:828 Lumbricus rubellus (humus earthworm) 30:826-828,833 assay of 30:833 earthworm fibrinolytic enzymes from 30:826 from Lumbricidae family 30:828 isozymes of 30:826 lyophilized powder of 30:840 Lumbricus terrestris (common earthworm) 30:828
487
from Lumbricidae family 30:828 ~-Lumicolchicine 5:47-49 [3-Lumicolchicine 5:47-49 Luminol-enhanced chemiluminescence 22:346 Lumnitzera sp. 7:176 Lupeol 7:189 Lunacarine 3:385,386 Lunaric acid 2:288,289;22:630,631 Lundt and Horneman 29:456 carbafuranose synthesis by 29:456 Lung tumors 25:46 induced by 4-(methylnitrosamino)-l-(3- pyridyl)- 1butanone (NNK) 25:46 Lungshengrabdosin 15:120 13C-NMR of 15:134 from Rabdosia lungshengensis 15:173 ~H-NMR of 15:127 Lupane 23:692 Lupane triterpenes 22:105,117 Lupane triterpenoids 24:457;25:60,61 FPTase inhibition by 24:457 Lupanes 22:94;25:61 betulin 25:61 (+)-Lupanine 15:520 Lupanine 21:73,91,95,98 (+)-Lupanine N-oxide 15:523 Lupenyl cation 25:176 Lupeol 9:267,20:698;27:478;29:587 effects on CHY 29:587 from Salvia glutinosa 20:707 from Salvia montbretii 20:704 from Salvia pomifera 20:702 Lupeol acetate 25:62 Lupeol palmitate (lupeol hexadecanoic acid ester) 29:587 effects on CHY 29:587 synthesis from lupeol 29:587 Lupeyl acetate 27:590 Lupin alkaloids 15:519-549 epi-Lupinamine 14:739,742 biomimetic synthesis of 14:739, 742 enantioselective synthesis of 14:741,742
Lupinamine 14:739,742 biomimetic synthesis of 14:739, 742 enantioselective synthesis of 14:741,742 Lupine alkaloids 14:731-768;27:258 biological activity of 27:258 structure of 27:258 synthesis of 14:731-768 Lupinine 14:731,732 from dihydropyran 14:737 from piperidine acetic acid 14:738 selectivity of 14:737,738 synthesis of 14:731,737,738 (-)-Lupinine 15:520 (+)-Lupinine 16:462;18:345,356,370 synthesis of 16:462 Lupinoside PA~ 25:95,104,105,118 Lupinoside PA2 25:95 Lupinoside PA3 25:118 Lupinoside PA4 25:95,104,105,118 Lupinoside PA5 25:95 Lupins 21:98 Lupinus albus 26:931 ;27:271,276 Lupinus anagyroides 27:283 Lupinus angustifolius 27:276 Lupinus hartwegii 27:273 Lupinus luteus 15:521 ;27:267;29:587, 782 (-)-( trans-4'-[3-Oglucopyranosyloxy-cinnamoyl) lupinine from 15:521 (-)-(trans-4'-[3-Dglucopyranosyloxy-3 'methoxycinnamoyl) lupinine from 15:521 (- )-( tra ns-4 ' -hydro x y-c inna mo yl ) lupinine from 15:521 (-)-( trans-4 ' -rhamnos ylo x ycinnamoyl) lupinine from 15:521 (-)-(trans-4 '-rhamnos yloxy-3 'methoxy-cinnamoyl) lupinine from 15:521 Lupinus mutabilis 27:278 Lupinus polyphylus 25:94 Lupinus sp. 27:273,268
488
Lupinus termis 15:524,525 (-)-AS-dehydroalbine from 15:524 (-)-ALdehydromultiflorine from 15:525 Lupinus varius 27:273 Lupinyl moiety 27:285 Lupus nephritis 26:269 Lushanrubescensin A 15:120 13C-NMR of 15:134 from Rabdosia rubescens 15:174 from Rabdosia rubescens var. lushiensis 15:174 IH-NMR of 15:127 Lushanrubescensin B 15:120 t3C-NMR of 15:134 from Rabdosia rubescens var. lushiensis 15:174 ~H-NMR of 15:127 Lushanrubescensin C 15:118 13C-NMR of 15:131 from Rabdosia rubescens 15:173 from Rabdosia rubescens var. lushiensis 15:174 ~H-NMR of 15:125 Lushanrubescensin D 15:118 13C-NMR of 15:131 from Rabdosia rubescens var. lushiensis 15:174 IH-NMR of 15:125 Lushanrubescensin E 15:118 13C-NMR of 15:132 from Rabdosia rubescens var. lushiensis 15:174 IH-NMR of 15:125 (-)-Lusitanine 15:522 from Maackia amurensis 15:522 Luteic acid 5:299 Lutein 7:20,98,320,336,350,351,352, 363,584,727,733;30:525 absolute configuration of 7:360 C-3 hydroxylation of 7:359-361 from Calendula officinalis 7:361 structure of 30:525 Lutein 3'-methyl ethers 30:546 formation of 30:546 from lutein 30:546 Luteolin 5:497;7:206,207,227;22:317, 661 ;25:541,543,544,593,595,615;
26:746,750,757,762,763,769;28:286; 29:579 absorption of 28:286 effects on ACE 29:579 effects on HIV- 1 protease 29:573 effects on NEP 29:581 effects on PEP 29:589 from Salvia limbata 20:712 from Salvia montbretti 20:712 from Salvia nemorosa 20:712 from Salvia sclarea 20:712 from Salvia yosgadensis 20:712 glycoside of 26:757 Luteolin-7,3 '-dimethylether 30:745,746 structure of 30:745 Luteolin-7-O-[3-glucoside 28:286 absorption of 28:286 Luteone 21:318,319;22:458 Luteorosin 17:12 Lutessine 26:610,612 2,6-Lutidine 6:445,447;7:154 monomorine I from 6:445,447 Lutinizing hormone-releasing hormone 27:794,796 Luttariella sp. 25:694 Lutzomyia 26:783 Luvangetin 23:342 Luzonicoside 7:294 from Echinaster luzonicus 7:294 Luzonicoside A 15:59,60 L-xylo-heptulosonic acid 30:434 stereoselective synthesis of 30:434 L-xylo-hex-2-ulosonate 20:858 Lyase 17:480 7:294 Lychnophora sellowii 8:48 bisabolone from 8:48 Lycium chinense 22:721 Lycoconjugates 29:554 et-L-fucose as 29:554 [~-D-galactose as 29:554 a-D-glucose as 29:554 [3-D-glucose as 29:554 Lycogalic acid 29:231 from tryptophan 29:231 Lycoctonine 20:22;26:868
489
Lycogala epidendrum 29:230,231,233 anti HSV-I virus activity of 29:230 arcyriaflavin A from 29:231 arcyriarubin A from 29:231 as myxomycete species 29:230 fruit bodies of 29:231 lycogarides as 29:233 lycogarubins from 29:230 staurosporinone from 29:231 Lycogalic acid 29:231 from oxidative dimerization of 3-(indol-3-yl)pyruvic acid 29:231 synthesis from methyl 3-(indol3-yl)pyruvate 29:231 Lycopene 7:318,319,321,322,327-354, 358;20:561,587,588,725;26:299,300; 30:525 in prostate cancer prevention 30:525 structure of 30:525 (7Z,9Z,7'Z,9'Z)-Lycopene 7:330,335 from (9Z,7Z,9Z)-neurosporene 7:332 Lycopersene 7:325,326 Lycopersicon esculentum 18:523,529, 532,533;25:294,298,657;29:591,604, 608,610
Lycopersicon hirsutum f. glabratum
28:433 2-undecanone from 28:433 methyl ketones 2-tridecanone from 28:433 Lycopersicon peruvianum 25:372-375 Lycopersicon pimpinellifolium 25:294, 298 Lycopersicon sp. 25:293,315 Lycopersicum esculentum 22:721 Lycopersion sp. 22:344 (+)-Lycopodine 18:321 Lycopodium alkaloids 16:456;18:341; 18:3-7 Lycopodium magellanicum 18:3 Lycopodium paniculatum 18:3 Lycopodium selago 21:746 selagin from 21:746 Lycopodium serratum 21:744 Lycopsamine 1:269;26:874
Lycoramine 4:13 from Amaryllidaceae 4:3,4 retrosynthesis of 4:4,5 synthesis of 4:20-23 c~-Lycorane 1:337 synthesis of 1:337 ~,-Lycorane 16:427 Lycorenine 20:351,20:352 Lycorenine model synthesis 1:333,334 Lycorine 20:234,347,351,356,367,368, 384;21:97;22:29;26:581,609-614, 617,618 from Narcissus pseudonarcissus 20:233 Lycoris incarnata 20:351 incartine from 20:351 Lycoris radiata 26:614 [3-Lycotetraose 25:295,296,297,300, 306,315 Lycotetraose 25:316,317 Lydicamycin 28:126 as antibacterial agent 28:126 Lygos raetarn var. sarcocarpa 27:269 Lymphatic filariasis 12:9 Lymphocyte 15:369;30:60 accumulation of 30:60 Lymphocyte proliferation 27:693 Lymphocyte transformation 25:224, 225,226 Lymphocytic leukemia 21:158;26:925 Lymphocytic leukemia system 18:696 Lymphoid leukemia 4:723 Lymphokine-activated killer 26:923, 951 Lymphokines 25:271 Lyngbia gracillis 19:586 Lyngbia majuscula 19:492,587 Lyngbya bouillonii 25:891 Lyngbya genus 25:891 Lyngbya gracilis 17:4 Lyngbya lagerheimii 25:868 Lyngbya majuscula 5:411 ;11:278; 18:294;21:415;23:344;25:716,722, 732,761,785,787,889;26:78;28:143 lyngbyatoxin from 11:278 pukeleimide A,B,F and G from 21:415 pukeleimide C from 28:143
490
Lyngbya toxin A 5:412 cytotoxic activity of 5:411 Lyngbya wollei 26:355 Lyngbyapetin A 25:891 Lyngbyatoxin 11:278 from Lyngbya majuscula 11:278 (+)-Lyoniresinol 3-(x-O-[3-D-glucopyranoside 26:195 Lyophilization 11:271;19:703 Lypooxygenase inhibition 25:617 Lypooxygenase pathway 25:274 Lyratol 7:208 Lyrophagus longior 28:419 Lysergamide 21:68 Lysergic acid 4:604,605;11:201 synthesis of 4:604,605;11:201 Lysergic acid diethylamide (LSD) 25:531 Lysicamine 2:436;3:444 synthesis of 3:444 D-Lysine 27:795 Lysine malonate 26:366 Lyso PAP acetyltransferase activity 25:615 inhibition of 25:615 Lysocellin 15:455 Lysolecithines 27:66 Lysolipins 29:317 effects on bacteria 29:317 lytic activity of 29:317 (x(1,3)-Lysosoma 27:252 Lysosomal c~-mannosidase 27:524 Lysosomal [3-glucuronidase 21:177 Lysostaphin 6:398 Lysozyme 2:31,32;7:31,32,49,55,57 transition state analogues of 7:49 Lysozyme 22:83 Lysozyme mechanism 7:31-36,43,50 Lysozyme reaction 7:49 Lysyltyrosyl quinone (LTQ) 26:1261, 1268 Lytechinastatin 7:285 from Lytechinus variegatus 7:285 Lytechinus variegatus 7:285;15:104 lytechinastatin from 7:285 Lythgoe aldehyde 10:46 from D-carvone epoxide 10:46
Lythgoe-Inhoffen diol 10:49,50 Lythraceae 23:404,405 Lythrum aceps 23:404 D-Lyxitol 10:46 synthesis of 10:46 L-Lyxofuranose derivative 10:431 from 1,2-O-isopropylidene- ~-Lidofuranose 10:431 Johnson-Claisen rearrangement of 10:431,432 D-Lyxo-pentodialdofuranoside 4:176 Wittig olefination of 4:176 M~ receptor 21:18 M3receptor 21:18
Maackia amurensis 15:521,522 (+)- 13[3-hydroxymamanine from 15:522 (-)-lusitanine from 15:521 Maackia tashiroi 15:523 tashiromine from 15:523 (+)-Maackiain 4:385,386 from chromene 4:385,386 synthesis of 4:385,386 (+)-7-Maaliene 23:162 (-)-lO-epi-Maalienone 14:359 Maaliol 6:28 (-)-[3-gorgonene from 6:28 Mabinlin 15:36 Macarangaflavanone b 28:229 biological activity of 28:229 Macaranoyl group 23:415 Macaronesia fortunata 26:850 Macarpine 14:781-783;22:77 from oxychelirubine 14:781-783 from sanguinarine 14:779 synthesis of 14:781-783 via chelirubine 14:779 Macbecin 21:420,435;23:54 (+)-Macbecin I 21:440 Macbecin I 3:233;10:150,153;23:90 ansa moieties 23:91 biosynthetic building units of 23:90 13C-NMR spectra of 23:90 Macbecin II 10:153 Macfadyena unguis-cati 29:696
491 Macfarlandin A-E 17:11,12 mAch receptors 21:108 Machililin G 26:242 as PAF-induced inhibitor 26:242 Machilin A 26:217 inhibitory activity of 26:217 Machilusjaponica 26:857 bioactive lignans from 26:857, 858 Machilus thumbergii 26:247 MacLafferty rearrangement 6:443 Macleaya cordata 27:155,159,162,864 Macleaya microcarpa 27:155,159,162 Macleaya sp. 27:162 Maclura pomifera 25:391 Macralstonidine 13:383,392,405,406 Macralstonine 13:383,392,405 Macroalgae 19:549;21:302,305 Macrocalin B 15:138,146,173;19:555 from Rabdosia macrocalyx 15:173 IH-NMR of 15:146 Macrocalyxin A 15:112,143,161 13C-NMR of 15:173 from Rabdosia macrocalyx 15:173 from R. macrocalyx var. jiuhua 15:173 ~H-NMR of 15:152 Macrocalyxin B 15:112 from Rabdosia macrocalyx 15:173 Macrocalyxin C 15:112 from Rabdosia macrocalyx 15:173 Macrocalyxin D 15:116,123 13C-NMR of 15:130 from Rabdosia macrocalyx 15:173 IH-NMR of 15:152 Macrocalyxin E 15:116 13C-NMR of 15:130 from Rabdosia macrocalyx 15:173 IH-NMR of 15:123 Macrocalyxoformin A 15:141,150,158, 172-174 13C-NMR of 15:158 from Rabdosia henryi 15:172
from Rabdosia macrocalyx 15:173 from Rabdosia sculponeata 15:174 1H-NMR of 15:150 Macrocalyxoformin B 15:141,149 from Rabdosia macrocalyx 15:173 ~H-NMR of 15:149 Macrocalyxoformin C 15:141 13C-NMR of 15:158 from Rabdosia macrocalyx 15:173 IH-NMR of 15:150 Macrocalyxoformin D 15:142 13C-NMR of 15:159 from Rabdosia macrocalyx 15:173 IH-NMR of 15:151 Macrocalyxoformin E 15:142 Z3C-NMR of 15:159 from Rabdosia macrocalyx 15:173 lH-NMR of 15:151 Macrocarbocyclic rings 8:16-18 synthesis by titanium 8:16-18 with TIC13/Zn-Cu 8:16-18 Macrocarpamine 13:393 Macrocycle 8:175-201,219-256;10:280, 281 synthesis of 10:280,281 Macrocyclic [2,3]-Wittig rearrangements 8:196 Macrocyclic cytochalasans 13:115-120 synthesis of 13:115-120 Macrocyclic derivative 6:495 from tetrahydroisoquinoline precursor 6:495 Macrocyclic diary ether heptanoids (Type IV) 26:899-901,905 Macrocyclic diarylether glycosides 17:367 Macrocyclic diarylheptanoids 17:387 synthesis of 17:387 Macrocyclic diterpenes 8:221 Macrocyclic hydrocarbons 8:15-31 Macrocyclic lactam antibiotics 23:51,54 classification of 23:51,54 Macrocyclic lactams 23:51
492
Macrocyclic lactones 12:243;17:75 as a defence secretion 8:220 Macrocyclic lipids 11:464 from Calderiella sp. 11:464 Macrocyclic pyrrolizidine dilactones 1:270-275 Macrocyclic quinolizidines 21:267 Macrocyclic reaction 8:175-201 Macrocyclic sesquiterpene alkaloids 23:673 Macrocyclic spermidine alkaloids 23:519 Macrocyclic transannular reaction 8:187-201 conformational control in 11:152-163 of geranyl geranyl pyrophosphate 11:24 with Hanessian's epi-merization 12:28 Macrocyclic trichothecenes 30:751 in vivo toxicity of 30:751 inhibition of protein synthesis 30:751 paralysis of skeletal muscles due to 30:751 respiratory depression due to 30:751 Macrocyclization 4:591;8:21;11:24,152, 158,163;12:28 by allychromium species 3:81 by dicarbonyl coupling 3:80 by Michael additions 3:83 by Nicholas reactions 3:83,84 by transannular acylation 3:81 for synthesis for 8-membered rings 3:80-84 polymer supported 3:82-83 transition metal mediated 3:80, 83 Macrocystis alterniflorum 26:359 Macrocystis spicatum 26:359 Macrocystis verticilatum 26:359 Macrodithiolactones 10:227,228 by macrolactonization 10:227 by sulphurization 10:227,228 from hydroxy acids 10:227 Macrofoulers 17:99
cx2-Macroglobulin 30:836 aspartate inhibition by 30:836 cysteine inhibition by 30:836 metallo-proteases inhibition by 30:836 serine inhibition by 30:836 Macroheterocyclization 16:423 palladium mediated 16:423 Macrolactamization 25:712 Macrolactonization 1:445,452,453,461, 462,464,465 ;8:233-242;9:246,247, 290;12:244;13:115,20 A2'3Macrolide 12:13 Macrolide antibiotics 3:277-281 ;5:606, 609,613;195 ;13:155-185,664 ;21:373; 29:321 acetylspiramycin 5:609 against Caenorhabditis elegans 29:321 against human tumors 29:321 ansamitocin P3 as 29:321 antitumor activity of 29:322 antiviral effects of 29:322 as vitamin K antagonist 29:322 biosynthesis of 11:192;29:322 chlorothricins as 29:322 colubricidin A as 29:321 cytotoxicity of 29:321 difficidin 5:609 erythromycin 5:609 in carcinoma 29:321 in leukemia 29:321 methylmalonyl CoA with 11:196 naphtomycins as 29:322 nematocidal activity of 29:321 oleandomycin 5:609 oxydifficidin 5:609 roseophilin as 29:322 synthesis of 12:35-62 Macrolides 3:277-281;4:513-520;5:609, 356,357,6:272-277 ;9:246,247,290; 8:175-201,222;16:658-662;22:33; 24:541-544 as antiviral compound 24:541-544 absolute configuration of 5:609 from ketophosphonate 6:276,277 structure determination of 5:609 synthesis 4:513-520;8:175-201
493
c0-1 hyroxylation of 8:222 e0-hyroxylation of 8:222 13-oxidation of 8:222 Macroline 13:398 alstonerine from 13:398 biomimetic transformation of 13:398 synthesis of 13:383,411,423,424 Macroline-related alkaloids 13:384-394 classification of 13:384-394 synthesis of 13:383-432 MACROMODEL 17:494,500,529,540 Macromycetes 22:568,579,582,599 Macronesia fortunata 26:850,851 Macrophage prostaglandins 22:25 Macrophage-mediated cytotoxicity 26:910 Macrophages 25:473 effect of TNF-a 25:473 Macrophiotrix longipeda 7:309 Macrophomis phaseolina 6:555 Macrophyllin B 15:173 from Rabdosia longituba 15:173 Macrophyllosaponin A 25:199 Macrophyllosaponin B 25:198 Macrophyllosaponin C 25:199 Macrophyllosaponin D 25:199 Macropiper excelsum 22:393 Macrosalhine 13:389 Macrospegatrine 13:391,396 Macrostamine 4:547 Macrotanacin 27:580 Macrotermitinae 8:220 Macrotyloma axillaris 29:598 Macrozamia communis 26:366 Maculatoside 7:290 from Linckia laevigata 7:290 from Luidia maculata 7:289 Macusine B 13:387 Madelung reaction 1:52 Maderrhodins B 5:617,618 Maduralide 19:559 Maduramicin 26:451 Maerua angolensis DC. 22:525 for epilepsy 22:525 Maesa lanceolata 5:819;17:240;21:665 Maesanin 5:819-823 ~3C-NMR spectrum of 5:820
from Maesa lanceolate 5:819 1H-NMR spectrum of 5:819 reaction with C1CH2OCH3/ NaH/DMF 5:822 reaction with KOH/EtOH 5:822 reaction with MCPBA/CH2C12 5:822 synthesis of 5:822 Magainans 22:82 Magainin-2 27:807 anticancer activity of 27:807 Magainins 27:807 Magellanine 18:3-7,665 Magellaninone 18:3-7 Magellanol 18:746 Maghtun 23:656 Magic bullet 9:491,492 Magireol A 5:363 Magireol B 5:363 Magireol C 5:363 Magllanesine 6:470 from oxyberberine 6:470 Magnamycin B 5:613 Magnifera indica 9:321 Magnificol 27:590 Magnoflorine 25:528 (+)-Magnoflorine 30:564,589 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:589 Magnograndiolide 27:580 Magnolia acuminata 24:845-847 Magnolia biondii 24:845,854 PAF antagonists of 24:854 Magnolia compbellii 24:849,857 Magnolia denudata 24:845,848,860; 26:245,247 Magnolia fargesii 24:854,862;26:233 denudatin B from 26:233 fargesin from 26:233 fargesone A-C from 26:233 lirioresinol-B dimethyl ether from 26:233 magnolin from 26:233 magnone A&B from 26:245 PAF antagonists of 24:854 pinoresinol dimethyl ether from
494
26:233 schisandrol A from 26:245 Magnolia grandiflora 24:845,848,850, 856,858,859,863 Magnolia henryii 24:855 Magnolia kobus 24:846,860,862 Magnolia liliflora 24:854,855,860 5-1ipoxygenase-inhibitory activity of 24:855 neurotropic activity of 24:854 Magnolia mutabilis 24:849,857 Magnolia obovata 24:854,855,857; 26:226,227,254 ;29:582 Magnolia officinalis 22:525;24:228, 261,846,849,851,855;26:226,249; 27:853;29:582 anti-tumor activity of 24:849 magnolol from 26:249 Magnolia officinalis var. biloba 24:846 Magnolia salicifolia 17:348;24:846, 860,887,888 ;26:233 Magnolia saulangiana 24:854 Magnolia sieboldii 24:848;29:89 Magnolia sp. 8:159;24:845-873;26:240, 270 biologically active compounds from 24:845-873 honokiol from 26:240,270 magnolol from 26:240,270 neolignans from 8:159 Magnolia sprengeri 24:845,849,851 Magnolia tripetala 24:847 Magnolia virginiana 24:845,847; 26:203,232 4,4'-dialyl-2,3'-dihydroxybiphenyl ether from 26:232 magnolol from 26:232 4-methoxyhonokiol from 26:232 Magnolia watsonii 24:855,857 Magnoliae cortex 26:204 honokiol from 26:204 magnolol from 26:204 Magnolialide 7:213;27:554 (+)-Magnolin 26:200 Magnolin 26:233,268 Magnoliophyta 18:740 Magnolioside 7:224 Magnolitae 18:740
Magnolol 22:525,540;24:861; 26:227, 232,240,249,254 ;29:582 anti-fungal activity of 24:861 as PAF-induced inhibitor 26:240 effects on MMP 29:582 Magnomycin B 10:170 Magnone A 26:245 as PAF-induced inhibitor 26:245 Magnone A&B 26:199,245 Magnone B 26:245 as PAF-induced inhibitor 26:245 Magnosalicin 26:264 Magnosalin 24:888-890;26:262,263 inhibitory effect on ECs 24:888-890 inhibition of angiogenesis 24:888-890 Magnoshinin 26:262,263 Magnus 29:389,390 steganes synthesis by 29:389,390 Magnus's synthesis 14:821-830 of vinblastine analogues 14:821-830 of vincristine analogues 14:821-830 Mahmoodin 9:297,298 Maillard reaction 13:317-319 Maillard reaction products 23:479 Maistemonin 21:769 Maiten 23:656 Maititoxins 25:730 Majetich et al. 29:215 miltirone synthesis by 29:215 Majetich synthesis 6:32,33 of perforenone 6:32,33 Majidea fosteri 7:139,141 majideagenin from 7:141 triterpenoids of 7:139,141 Majideagenin 7:141 from Majideafosteri 7:141 Majonoside R2 21:672 Major histocompatibility complex 26:921,951 Majorenolide 9:402 Majorynoide 9:402 Majusculainides 25:716 Majusculamide C 23:344,349 Majvinine 13:386 Makaluramines 25:822,823
495
Makaluvamines 21:311;25:707,708,757 Makaluvamin F 25:824 Makaluvamine A 29:253 as topoisomerase II inhibitor 29:253 pyrroloiminoquinone structure of 29:253 Makaluvamine A-E 25:700 Makaluvamine D 21:311 Makaluvamine F 25:700 Makaluvamine N 25:700 Makisterone A 19:628 (+)-Makomakine 11:278,279 (+)-aristoteline from 11:292-295 synthesis of 11:280-283 Malabaricane triterpenoids 25:700 Malabaricane triterpenes 25:700 Malabaricanediol 17:611 Malabatrin B 23:404 Malabatrin C 23:404 Malabatrin D 23:404 Malacosoma americana 23:661 Malagashanine 26:1053,1054,1063, 1064 Malagashanol 26:1053,1064,1065 Malampsori lini 25:397 Malaria 26:804;30:561,597 treatment of 26:804 use of Hernandia moerenhoutiana in 30:561 use of Hernandia nymphaeifolia in 30:561,597 use of Hernandia voyronii in 30:561,597 Malaria pigment 25:332 Malarial fever 28:202 use of Artocarpus venenosa against 28:202 Malate dehydrogenase 26:800 MALDI 19:751 MALDI mass spectroscopy 26:11 Maleic acid 7:180 in mangrove plants 7:180 Maleic anhydride methylvinyl ether copolymer (MAMEC) 30:844 m-Maleimidobenzoyl-N-hydroxysuccinimide ester 18:911 Malekulatine 26:824,825,827
(+)-Malekulatine 30:566,584,590,594 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 as platelet aggregation inhibitor 30:594 cytotoxic effect of 30:589 N~-Maleoyl- [3-alanyl-gastrin- [2 - 17] derivatives 18:913 Malibatol A&B 23:533;26:562 R-(+)-Malic acid 16:691 L-Malic acid 4:125 chiral ylide from 4:125 in mangrove plants 6:263 in mangrove plants 7:206 (S)-Malic acid 8:140; 365;13:513; 14:521-527 dimethyl ketal from 11:346,347 reduction of 11:404 4,7-dioxaspiro [5.5] undecane from 14:521-526 2-methyl- 1,6-dioxaspiro [4.5] decane from 14:526-527 (-)-(S)-Malic acid 226 Malic acid dehydrogenase 7:387 (S)-Malic acid ester 6:287,290 (S)-butan- 1,2,4-triol from 6:287,290 Malic conjugates 28:262 in grapes 28:262 in lettuce 28:262 in spinach 28:262 in wines 28:262 Malignant tumors 21:158;30:841 Malkangni 23:654 Malkanguniol 18:744 Mallory stilbene photocyclization 3:305 Mallotannin A 23:406 Mallotannin B 23:406 Mallotusjaponicus 23:406 Mallotus philippinensis 27:853 Malondialdehyde 9:564;22:329;25:219 ene reaction of 6:225,226 Maloney murine leukemia virus 29:127 (MMuLV) inhibition by 29:127 Malonic acid 13:53,67 in mangrove plants 7:180 Malonic acid esters 25:251
496
Malonomicin 28:118 antiprotozoal activity of 28:118 Malonyl-CoA 9:341;11:194;23:89,742; 27:768 Malonylglucoside 30:257 Malonylsaikosaponins 15:191 Maltase-glucoamylase 10:498 Maltby's-generalization 4:200 Maltol 22:528,540 Malto-oligosaccharides 2:328;7:33, 34,39 Maltophilin 28:140 as antifungal agent 28:140 [3-Maltose 7:58 Maltose derivatives 7:62,63 Maltose-l-14C 2:332,333 hydrolysis by glucoamylase 2:332,333 4-O-Maltoside 8:349 3'-S-Maltosyl-glyc-2-enopyranoside maltotriose 8:343,345 Maltotetraoses 7:34,35 from taka amylase 7:34,35 Maltotriose 8:343,344;15:436 a-Maltotrioside 7:35 Malus domestica 29:577,582 Malus sylvestris 21:503 Malvaceae 5:751 ;7:185 Malvin-3,5-diglucoside 20:724 Malyngamide A 28:142 structure of 28:142 Malyngamide K. 25:787 Malyngamide L 25:787 Malyngamide M 25:787 (-)-Malyngolide 19:463 antimicrobial activity of 19:492 Malyngolide 3:157,158 Mam-2 assay system 29:87 3 D-acetoxy-8 [3-isobutyrylo xyreynosin activity in 29:87 (-)-Mamanine N-oxide 15:522 from Sophora chrysophylla 15:522 Mamanuthaquinone 15:300,315 Mammalian cell 30:592 carcinogenesis in 30:592 Mammalian cell mutation test 27:304 Mammalian lipoxygenases 30:225
Mammalian tissue 23:14 Mammalian toxicity 21:100 Mammary carcinoma 1:275 Mammea africana 7:417 Mammea americana 4:389,391 coumarins from 4:389,391 Mammea longifolia 4:389,391 coumarins from 4:389,391 sarangin B from 4:391 Manauealide A 25:771 Manauealide B 25:771 Manauealides 25:729,730 Mandarin 23:747 Mandelic acid 1:603 as chiral auxiliaries 1:603 (S)-Mandelic acid 12:473 (S)-(+)-Mandelic acid 13:468 (R)-Mandelic acid 19:355 (R)-Mandelohydroxamic acid 19:355 Mandragora 21:104 Mandragora officinarum 13:631;22:734 Mandshurin manica bradleyi 5:250 Manduca sexta 1:704;21:252;22:38, 387;26:439;29:6 juvenile hormone from 1:704 Maneonene 17:7 Mangamines 5:346-353 Mange mites 28:409 transmission of 28:409 treatment of 28:409 Mangicol A 29:111 activity in TPA bioassay system 29:111 Mangicol B 29:111 activity in TPA bioassay system 29:111 Mangifera genera 27:755 Mangifera indica 29:588 Mangifera odorata L. 22:525 for hysteroepilepsy 22:525 Mangle rojo 23:658 a-Mangostin 25:544;29:573 effects on HIV- 1 protease 29:573 ~,-Mangostin 25:544;29:573 effects on HIV- 1 protease 29:573 Mangrove plants 7:175-199 Manica bradlyi 5:250
497 Manica hunteri 5:250 Manica mutica 5:250 Manica rubida 5:235,254 2,5-dimethyl-3-methyl-pyrazines of 5:222 methyl pyrazine of 5:222 Maniladiol 22:122;29:587;30:718 effects on CHY 29:587 structure of 30:718 Maniladiol 3-O-myristate (Olean-12ene-313,16f3-diol 3-O-myristate) 29:587 effects on CHY 29:587 ~3-Mannan 23:109 Mannans 5:280-285,291,292,299,306, 323,324 Mannans and oligomers 26:1158 synthesis of 26:635-637,642 Mannich base methiodide 14:406-408 condensation of 14:406-408 with thujone 14:406-408 Mannich condensation 6:39 in (+)-stoechospermol synthesis 6:39 Mannich reaction 1:244;6:39;9:332; 13:473;16:481 intramolecular 14:746 of dimethyl c~-ethylmalonate 14:850 with diethylamine 14:850 with vitamin 4:715 Mannich-Aldol condensation 12:293 D-Mannitol 3:225;9:288;14:633; 15:426;18:157,159 (4S)-hydroxymethyl butanolide from 6:292 dehydration of 3:225 8-Mannitol 21:690 Mannitol 21:738;24:1007,1008 occurrence of 24:1007,1008 D-Mannitol diacetonide 18:157 D-Mannofuranose 6:355 phosphorus analogues of 6:355 Mannoglucogalactan 5:300 Mannojirimycin 7:42;10:538-542,550 from Streptomyces lavendulae 10:538
mannosidase inhibition with 7:41 (+)-Mannonolactam 18:347 Mannonolactone 7:49 Manno-oligomers 26:1126 1,4-~-D-Mannopyranose 27:511 Mannopyranose 7:47 D-Mannopyranose system 4:201 C~ chain elongation of 4:201 D-Mannopyranoside 6:373,374 cz-D-Mannopyranosyl 1-thio-cx-Dmannopyranosides 8:319,321,347, 348 cx-L-Mannopyranosyl glycosides 7:70 cx-D-Mannopyranosyl (z-D-mannopyranoside 8:347 2-c~-Mannopyranosyl- 1-phosphatidlylD-myo-inositol 18:449 L-Mannose 10:413 Wittig methylenation 10:413 D-Mannose 4:199,200,354 Mannose 7:181 D-Mannose-6-(D-mannosyl phosphate) 5:284,285 D-Mannose-molybdate complex 15:434 ER cz-l,2-Mannosidase 10:501,559 cx-1,3-Mannosidase 10:559 c~-1,6-Mannosidase 10:559 c~-Mannosidase 19:354,356-357 lysosomal 19:487 Mannosidase 19:356 inhibitor of 19:356 mannojirimycin inhibition by 7:41 [3-Mannosidase 7:11,15;10:567,568 ot-D-Mannosidase 7:11 Mannosidase II 19:487 c~-Mannosidase inhibitor 1:331 synthesis of 1:331 c~(1,6)-Mannosidases 27:252 ct-Mannosides 8:359 Mannosidosis 7:11 ct-Mannosidosis 7:12 by swansonine 7:12 Mannostatin A 19:351-352 absolute stereochemistry of 19:352 structure of 19:352
498
2-epi-Mannostatin A sulfone 19:356 Mannostatins 10:523,524 Mannostatins A & B 10:523,524 a,D-mannosidase inhibitors 10:523 from Streptoverticillium verticillus var. quintum 10:523 Mannostatins A & B 10:523,524 ct,D-mannosidase inhibitors 10:523 Mannosyl chloride (2,3,4,6-tetra-a-Obenzyl-a-D-mannopyranosyl chloride) thermal glycosidation 8:359-361,366 Mannosylated phosphoinositides 18:393 Manoalide 3:157,158;18:717;21:252; 29:111 activity in PLA bioassay system 29:111 antibacterial activity of 16:666 inflammatory activity of 16:666 inhibitory activity of 16:666 Manool 6:122;25:253,254,259;26:402 biosynthesis of 25:253,254,259 in (+)-confertifolin synthesis 4:424,25 in (+)-euryfuran synthesis 4:422-424 in (-)-warburganal synthesis 4:419,420,424,425 from Salvia limbata 20:691 from Salvia sclarea 20:691 (+)-Manool 6:28,55-57 ent-methyl isocopolate from 6:56,57 in 14-deoxy-taondiol methyl ether synthesis 6:55 in (+)-euryfuran synthesis 6:28 in (+)-isoagatholactone synthesis 6:56,57 ct-D-Manopyranoside 21:442 Manosonone E 3:446,451 synthesis of 3:450,451 Manosonone F 3:450 synthesis of 3:450 Manosonone I 3:450 synthesis of 3:450
13-epi-Manoyl oxide 25:250;29:102 activity in EBV bioassay system 29:102 ent-Manoyl oxide- 16-hydroxy-18-oic acid methyl ester 25:261 ent-Manoyl oxides 25:264 Manoyl oxide 20:691;25:245,248-250, 253-255 from Salvia candidissima 20:691 fragmentation of 25:255 ent-13-epi-Manoyl oxide 25:253,261, 266,267 Manoyl oxide F1 29:102 activity in PLA bioassay system 29:102 Manoyl oxide isomer 25:259 Manoyl oxide series 25:258,259 Manoyl oxides 25:255 Manoyl oxides epigomeric acid 25:267 Mansonone H 5:773 Mantella basileo 27:246 Mantella sp. 27:244 1-p-Manthene 25:145 Manumycin 21:375,398 Manumycin family 21:398 from 2-amino-3-hydroxycyclopent-2-one 21:398 Manumycins 24:435-437 inhibitors of FPTase 24:435 structures of 24:436 Manumycins A,B,C and D 21:398 Manumycins B,C and D 21:403 Manzamenone C 23:204 Manzamenone D 23:204 Manzamenone E 23:204 Manzamenone F 23:204 Manzamenone G 23:204 Manzamenone H 23:204 Manzamenone J 23:204 Manzamenone K 23:204,211 biogenesis of 23:204,211 Manzamenone metabolites 23:201 Manzamenones B 23:204 Manzamines 21:260,308;24:573,575, 614-616,621-645;25:709 biosynthesis of 24:573 synthesis of 24:614,615, 623-645,669
499 Manzamine A 5:346,348,350;21:260, 261,262 Manzamine B 5:346,347,349,350 Manzamine C 5:346,347,350;21:308, 260,261,262 Manzamine D 5:346,347,350 Manzamine E 5:350 Manzamlne F 5:346-353 Manzarmne J 21:260,261,262 Manzamme N oxide 21:260 Manzamine-D 21:261,262 Manzamlne-F 21:261,262 Manzamine-X 21:261,262 MAO A 30:377,382 deamination of dopamine by 30:377 deamination of serotonin by 30:377 deamination of noradrenaline by 30:377 in fetal brain 30:377 MAO B 30:377 deamination of dopamine by 30:377 deamination of benzylamine by 30:378 deamination of neurotransmitters by 30:378 deamination of phenylethylamine by 30:378 in adult brain 30:378 MAO inhibitors 21:84,101 MAOA gene 30:380,382 aggressive behavior of 30:380 in knockout mice 30:380 Maoecrystal A 15:137 13C-NMRof 15:154 from Rabdosia eriocalyx 15:171 from Rabdosia eriocalyx var. laxiflora 15:171 IH-NMR of 15:145 Maoecrystal B 15:138,176 13C-NMR of 15:155 from Rabdosia eriocalyx 15:171 from Rabdosia eriocalyx var. laxiflora 15:171 ~H-NMR of 15:146 Maoecrystal C 15:138 laC-NMR of 15:155
from Rabdosia eriocalyx 1H-NMR of 15:146 Maoecrystal D (rabdolongin B) 15:112,138 13C-NMR of 15:155 from Rabdosia eriocalyx from Rabdosia longituba IH-NMR of 15:146 Maoecrystal E 15:139 from Rabdosia eriocalyx tH-NMR of 15:147 Maoecrystal F 15:139 13C-NMR of 15:156 from Rabdosia eriocalyx JH-NMR of 15:147 Maoecrystal G 15:138 from Rabdosia eriocalyx IH-NMR of 15:146 Maoecrystal I 15:139 13C-NMR of 15:156
15:171
15:171 15:173
15:171
15:171 15:171
from Rabdosia eriocalyx 15:171 IH-NMR of 15:147 Maoecrystal J 15:139 13C-NMR of 15:156 from Rabdosia eriocalyx 15:171 IH-NMR of 15:147 Maoecrystal K 15:139 13C-NMR of 15:157 from Rabdosia eriocalyx 15:171 IH-NMR of 15:148 Maoyerabdosin 15:139 13C-NMR of 15:156 from Rabdosiajaponica 15:172 IH-NMR of 15:147 Maprounea africana 22:525 Marasmic acid 13:6;26:462 Marasmius 26:462 Marcfortine A 26:490,491;28:331,332, 336,372 antiparasitic activity of 28:332 conversion to paraherquamides 28:372 reaction of 28:336 spiroalkyl analogs of 28:355 structure of 28:332 Marchantia paleaceae 2:281 Marchantia palmata 2:283 Marchantia polymorpha 25:423 Marchantia tosana 2:281
500
Marchantin A 2:108,281,282 Marchantin A trimethyl ether 2:104,105 Marchantin D 2:282 Marchantin E 2:282 Marchantins 2:112,282,283 from liverworts 2:103 from Marchantia paleacea 2:103 from Marchantia polymorpha 2:103 from Marchantia tosana 2:103 structure of 2:109 Marchantins A-C 2:282 Maremycins A and B 25:828 Marfat-Helquist annulation 13:11,12 Margarita 22:559 Margaritaria discoidea 28:395,406 acaricidal activity of 28:406 acaricidal properties of 28:395 Margocinin 9:297,299 Margolone 9:297,299 Margosinolide 9:297,298 Margosone 9:297,299 Maridomycins 11:164 Maridonolides 11:160,163-172 stereoselective synthesis of 11:163-172 Marijuana 19:137 Marine algae 20:25 crinitol from 20:25 Marine alkaloids 29:426 chiral building blocks of 29:427 clavepictines A as 29:426 cytotoxic activity of 29:426 lepadine B as 29:426 ictamine as 29:426 Marine alkaloids synthesis 29:427 by Kibayashi's group 29:432 enantioselective 29:426 Marine animals 9:3-14 novel natural products from 9:3-14 Marine arthopodes 19:627 Marine bacteria 21:295 Marine bioactive compounds 24:537-672 biochemical aspects of 24:573-672 structures of 24:573-672 synthesis of 24:573-672
Marine diterpenoids 6:52-54 dolastanes in 6:52 from Dictyotaceae 6:52 from Dictyota indica 9:78-81 Marine fatty acids 26:63 Marine fungi 24:981,1005,1006,1048, 1049,1051-1055,1078-1081, 1084-1086 anti-bacterial substances of 24:1049,1051,1084 anti-fungal substances of 24:1049,1052,1053 anti-malarial substances of 24:1055 anti-microalgal substances of 24:1055,1084 anti-microbial substances of 24:1049,1054,1084 anti-parasitic substances of 24:1049,1084 anti-viral substances of 24:1053 pharmacological aspects of 24:1048,1049,1084-1086 toxicological aspects of 24:1048, 1049,1084-1086 Marine invertebrates 9:493-495 neuropeptide from 9:493-495 Marine isocyanide biosynthesis 21:361 Marine isocyanides 21:330 ecology of 21:364 biology of 21:364 Marine lymphoma 23:187 cytotoxicity against 23:187 Marine macrolide 19:549 antifungal activity of 19:549 antitumor activity of 19:549 antiviral activity of 19:549 bioactive 19:549-626 cytotoxic activity of 19:549 immunomodulatory activity of 19:549 Marine molluscs 21:3 Marine N-acyl shingosine 9:85,86,88 from Halymenia porphyroides 9:85,86,88 Marine oxylipins 21:305 Marine prostanoids 1:687 Marine pyranopyrans 10:421,422 synthesis of 10:421,422
501
Marine pyridoacridine alkaloids 25:758 Marine quinones 15:289-326 Marine sesquiterpenes 15:289-326 from Laurencia pinnatifida 9:81-83 Marine sponges 10: 77-145 isoquinolinequinone from 10:77-145 Marine sterols 9:35-50 from Asparagopsis sandifordiana 9:83-85 from Myriogloia sciurus 9:83-85 Marine worm 21:3 Marinomonas mediterranea 25:719 Marinone 25:780 Marinovic extension 12:15 of Stork's vinyl radical cyclization 12:15 Maritimetin 22:424,427 Maritimin 7:232 Maritinone 2:213,215;5:754,755 Marjoram hortensis (sweet marjoram) 11:221 cyclase from 11:221 Markers 9:564 ethane as 9:564 in lipid autoxidation 9:564 pentane as 9:564 Markovnikov orientation rule 22:277 Marmesin 20:497;28:18 antifungal activity of 28:18 Marquesia 23:532 Marrubium alysson 30:266 7-glucoside from 30:266 Marrubium vulgare 30:266 luteolin from 30:266 Marschalk condensation 1:595 Marschalk reaction 4:346,347,350,352; 14:5,12 Marsglobiferin 27:47,48 structure of 27:48 Marshall synthesis 6:73 ;30:19-22 of (-)-dictyolene 6:27 of dihydrospiniferin- 1 derivative 6:72,73 of (+)-diseodermolide 30:19-22 Marshallia tenufolia 10:442,443 Marsilea minuta 22:526 Marsilea rajasthnensis 22:526
Marsilea sp. 22:525 Marsiline 22:526,525,540 Marthasterias glacialis 7:289,299; 15:48,104 glacialosides A,B from 7:299 Marthasterone 7:289 Marthasteroside A 15:47 Marthasteroside A~ 7:293 from Acanthasterplanci 7:288 from Linckia laevigata 7:288 from Nardoa gomophia 7:290 Marthasteroside A2 7:289 Marthasteroside B,C 7:289,293 Martin reagent 13:601 Martin sulfurane reagent 6:204,205 Martinellic acid 21:73 Martynia annua L. 22:526 for epilepsy 22:526 Martynia chamomilla L. 22:526 for hysteria 22:526 Martynia diandra 22:526 for epileptic attacks 22:526 Maslinic acid 7:134,135;29:575 effects on HIV- 1 protease 29:575 Maslinic lactone 7:135 from Terminalia alata 7:134 Mass fragmentation 23:544 of vaticaffinol 23:544 Mass spectra 23:35 ofSAMM 1 23:35 ofSAMM 2 23:35 Mass spectrometric analysis 9:447-486 ofsteryl esters 9:447-486 Mass spectrometry 5:265;9:165, 466-478 by direct sample introduction 9:466-469 chloesteryl esters analysis by 9:466-478 5-methylpyrazine 5:265 of 2,5 -dimethyl-3-isopentylpyrazine 5:259,260 of 2,5-dimethyl pyrazines 5:258 of 2,5-dimethyl-3-(2-methylbutyl) pyrazines 5:259,260 of 2,5-dimethyl-3,6dimethylpyrazines 5:258 of 2,5-dimethyl-3-
502
citronellylpyrazine 5:261 of 2,5-dimethyl-3methylpyrazines 5:258 of 2,5-dimethyl-3-npentylpyrazine 5:259,260 of 5-methyl-3-(2-methylbutyl-2(E-3-methylpent- 1-enyl)pyrazine 5:263 of alkylpyrazines 5:258 of flavonoids 5:621,531-648 of enyl)pyrazine 5:263,265 of indole alkaloids 9:165 of methyl pyrazines 5:258,265, 267 ofpyrazines 5:258-268 Mass spectroscopic ionization techniques 2:43-55 Mass spectroscopy 23:423 of ellagitannin oligomers 23:423 Massetolide A 21:296 Massetolides 21:296,297 Massetolides I,J and K 21:297 Massoia lactone 3:157,158 Massoilactone 21:197 Mast cells 27:806;30:367,370 activity of tryptophan hydroxylase (TPH) in 30:370 Masticadienoic acid 22:117,131 Mastigomycotina 9:202 Matadine 26:1060 (-)-Matairesinol 26:156,157,192 Matairesinol 5:488-493,522,526,530; 26:177,205,206,217,229,233 inhibitory activity of 26:217 O-glucosylation of 5:525 O-methylation of 5:525 Matairesinol 4'-O-glucoside 5:489-491 (-)-Matairesinol dimethyl ether 26:192 Matairesinol-di-[3-D-glucoside 5:522 (-)-Matairesinol-[3-D-glucoside 26:238 Matairesinoside 5:522 Maternal thalidomide 30:374 autistic features in 30:374 a-Mating factor pheromone 25:387 Matricanin 7:214,215,235 Matricaria aurea L. 22:526 for hysteria 22:526 Matricaria chamomilla 22:669
Matrigel 28:573 photograph of 28:573 Matrigel-implanted angiogenesis assay 30:62 activity of triterpenoid fractions in 30:62 Matrigel-induced angiogenesis 30:67,69 effect of oleic acid on 30:69 in vivo 30:67,69 (+)-Matrine 15:520;30:205 activation of kappa-opioid receptor by 30:205 activity in acid-induced abdominal contraction test 30:205 antinociceptive effect of 30:205 SAR of 30:205 Matrine 14:757;30:205 derivatives of 30:205 structure-activity relationship of 30:205 Matrix metalloproteinases 27:805 Matsumoto synthesis 14:670-676 of taxodione 14:670-676 Matteson method 26:1221 for dihalomethylithiation insertion 26:1221 Matteuccia orientalis 22:169 Matteucinol 22:169 Matthiola fruticulosa 26:1075 Mattucinol-7-O- [4",6"-O-(S)-hexahydroxy-diphenoyl]-[3-D-glucopyranoside (polyphenol glycoside) 29:571 inhibition of Candida albicans by 29:571 pepsin inhibition by 29:571 Maturation 30:378 serotonin action on 30:378 Mauiensine 9:183 Maurapyrone A-D 17:25 Maurenone 17:25,26 Mauritamide A 25:870 Maximal Electroshock Test (MEST) 22:508 (-)-MaximowiczioI A 26:899 Mayapple 26:149,152,153,171,175,176 Mayenus ebenifolia 23:657
503
(+)-Mayolide A 16:699-700 synthesis of 16:699-700 Mayotamide 25:884 Mayotamides A 25:883 Mayo-type sequence 12:198 Maytansine 4:491-493;9:433;11:5; 13:654;21:96;23:54,70 related compounds 23:70 synthesis of 4:491-493 Maytansinine 21:96 Maytansinoids 9:432,435;18:739; 21:421 (-)-Maytansinol 23:71 Maytansinol 23:71 Mayteine 23:681 Maytenfolic 23:694 Maytenfoliol 23:693,694 Maytenfolone 23:702 Maytenfolone-A 30:643,644 ~3C DEPT NMR data of 30:643 ~H DEPT NMR data of 30:643 2D NOE of 30:643 HMBC of 30:643 MS of 30:643 structure of 30:644 Maytennus umbellata 23:652 Maytenone 23:682 Maytenoquinone 23:682 Maytensifolia A,B 7:152 from Maytenus diversifolia 7:152 Maytensifolic acid 7:153 from Maytenis diversifolia 7:152, X-ray analysis of 7:152, Maytensifoliol 7:152 from Maytenus diversifolia 7:152 Maytenus amazonica 23:656;30:672, 674,679 dispermoquinone from 30:672 phenolic triterpenes from 30:679 Maytenus aquifolium 23:656;30:639 cyclase activity of 30:639 Maytenus arbustifolia 23:656 Maytenus blepharodes 23:656;30:684 dimeric compounds from 30:684 Maytenus boaria 18:752,775; 23:656,665
Maytenus buchanii 7:146;21:442 maysenine from 21:442 tissue culture of 7:146 triterpenes of 7:146 Maytenus buxifolia 18:757;23:657 Maytenus canariensis 23:652,657, 669;30:667 iguesterine from 30:667 Maytenus chuchuasea 23:657 Maytenus cuzcoina 29:87,88 Maytenus dispermus 30:672 7-oxoquinonemethide dispermoquinone from 30:672 Maytenus diversifolia 7:152;23:727 maytensifolic acid from 7:152 maytensifolia A,B from 7:152 maytensifoliol from 7:152 triterpenoids of 7:152 Maytenus emarginata 23:657 Maytenus genus 18:739,740 Maytenus heterophylla 23:657 Maytenus horrida 30:666 netzahualcoyene from 30:666 Maytenus idaea 23:659 Maytenus ilicifolia 23:657,694;24:285, 287 Maytenus krokovii 23:658,692 Maytenus laevis 23:658 Maytenus macrocarpa 30:657 dammarane triterpenes from 30:657 Maytenus magellanica 30:684 dimeric compounds from 30:684 Maytenus obscura 23:658 Maytenus ovatus 4:492;23:70 Maytenus peduncularis 23:658 Maytenus putterlickioides 23:658 Maytenus rigida 18:771 wilfordin from 18:771 Maytenus scutioides 23:713;30:665,692 fluoride derivatives from 23:713 15~-hydroxypristimerin from 30:665,692 scutione derivatives from 23:713 Maytenus senegalensis 23:659 Maytenus serrate 21:442 maysenine from 21:442 Maytenus sp. 30:693 against Candida albicans 30:693
504
against gram-negative bacteria 30:693 against gram-positive bacteria 30:693 Maytol 18:747 Mazethramycin 21:374 MC-1 6:135 MC-903 9:516,517 McCasland 29:466 pyranoid carbasugars synthesis by 29:466 McFayden-Stevens reduction 8:273 M-Chlorobenzimidates 22:292 McLafferty rearrangements 2:6;22:371 McMurry coupling 11:337,354 intramolecular 11:343,363,364 McMurry cyclization 11:27 McMurry reaction 9:250,255 intramolecular 11:337 McMurry reagent 13:601 MCPBA oxidation 8:216;29:373 in rhazinilam synthesis 29:373 MD (molecular dynamics) 10:269 MDL ISIS-Base 18:971 MDP 6:405;13:210-212 analogs of 6:405 by solid-phase method 6:405 2,3-diaminoglucosyl analogs of 6:385,407 immunadjuvant properties of 6:385 structure of 6:405 MDR 21:158 MDR-associated protein gene expression 21:158 4-Me-antirrinoside 7:455 Measles 30:408 immunization against 30:408 Measles virus (MV) 26:223;30:408,412 Measles virus (MV) replication 30:408 inhibitor of 30:408 Mebadonin 15:175 from Rabdosia umbrosa 15:175 Mecambrine 2:162 MECC 21:543 Mechanics 6:316,320 of acetal derivatives formation 6:335,336 of cyclization 6:314,345
Mechanism 4:638,639;30:368 of absicisic acid reception 27:322 of C (8) bromination of camphor 4:638,639 of C(9) bromination of camphor 4:633,634 ofbiomimetic olefin cyclization 1:671-674 of cyclization 7:335-338, 358-360 of Diels-Alder reaction 4:579, 580 of hydrogen phosphite method 4:277 of lithio dianion-imine condensation 4:444-447 ofphosphite method 4:272 ofphosphotriester method 4:270 of serotonin (5-HT) re-uptake inhibitors 30:368 Mechanistic aspects 9:591-609 of vitamin B12biosynthesis 9:591-609 Mechanistic features 27:821 of kinase 27:821 Mechilin A 26:191,217,268 Mechilin G 26:242,247 Mechilin racem ~us 26:1093 Meciadanol 25. o 18 Meconopsis genera 27:163 MECP2 gene 30:373 in Rett's disorder (RTT) 30:373 mutation in 30:373 Mecyadanol 22:429 Mederrhodin A 22:266 Mederrhodins 5:590 Mederrhodins A 5:617,618 Median antinocieptive dose (EDs0) 30:802 Mediated oxidation 26:991 ferrihemoglobin 26:985,986,991 Medicagenic acid 7:432,433 Medicagenic acid glycoside 21:661 Medicago polymorpha 25:93 Medicago sativa 15:202,20:734;21:518, 662;23:343 ;26:696;29:585 medicagenic acid glycoside from 21:661
505 Medicago scutellata 29:598 Medicago trunuclata 25:379 Medicarpin 26:473;27:498;28:229 biological activity of 28:229 Medicinal plants 17:421;24:877,878; 30:55 chronic inflammation alleviation by 24:887-895 effect on neuromuscular synapse 24:877,878 for allergic inflammation 30:55 for arteriosclerosis 30:55 for cancer 30:55 for coronary artery constriction 30:55 for coronary heart diseases 30:55 for diabetes 30:55 for hypertension 30:55 for thrombosis 30:55 for tumor metastasis 30:55 for tumors 30:55 Medicinal use 27:445 of Astragalus root 27:445 of Astragalus seeds 27:445 Medinillin A 23:404 (+)-Medioresinol 26:200,229 (+)-Medioresinol 4'-[3-D-glucoside 5:524 (+)-Medioresinol dimethyl ether 5:537 (+)-Medioresiol-di-13-D-glucoside 5:54 (+)-Mediorsinol 5:524,536-538 Mediterranean fever 30:194 use of A6-tetrahydrocannabinol (THC) 30:194 Medium pressure liquid chromatography (MPLC) 9:464 Medium ring ethers 10:201 biological activity of 10:201 synthesis of 10:201-239 Medorinone 18:338 Meerwein-Pondorf-Verley-Oppenauer 14:481 reaction intramolecular 14:481 Meerwein's reagent 8:205;12:289, 20:426 Meerwein's salt 12:300,305,320 Mefloquine 13:656;20:517,518;22:149; 26:782,783,838,839
(+)-Megacerotonic acid 26:185 Megalobulimus paranaqnensis 2:306 Megalosaccharide 10:459 (-)-Megaphone 16:705 synthesis of 16:705 Megaphone acetate 26:212 cytotoxicity of 26:212 a-Megaspermin 25:395 [3-Megaspermin 25:395 Megastigmane 10:152 Meglumine antimonate (glucantime) 26:822 Megnaporthe grisea 25:322 Mehranine 5:171,172 Meisenheimer rearrangement 6:468 ofallocryptopine N-oxide 6:468 of cis-(+)-laudanosine N-oxide 6:468 [1,2]-oxaza ring formation by 6:472 MEL-28 (human melanoma) 30:691 phenolic triterpenes against 30:691 Melaconis thelebola 26:596 Melaleuca acacoides 28:419 Melaleuca alternifolia 21:615 ;28:415; 29:83 Melaleuca argentea 28:418 Melaleuca dealbata 28:418 Melaleuca leucadendron 15:387 phyllodulcin from 15:387 Melaleuca quinquenervia 21:616 Melaleuca saligna 28:418 Melaleuca sp. 28:418 Melaleuca symphycarpa 28:419 Melampolides 7:210 from Artemisia gypsacea 7:211 Melanin formation assay 21:589 Melanine pigment 16:615 physiological role of 16:615 Melanins 26:1018-1020 biosynthesis of 26:1019 Melannorrhea usitata 9:319 Melanogenesis 26:965 Melanoma 1:275;21:634 Melanoma cells 16:90;21:590 Melanoplus sanguinipes 22:40 Melanoprorteins 26:1019 Melarsoprol 26:791,787
506
Melastoma malabatricum 23:404 Melastoma normale 23:404 Melastomataceae 23:404,405 Melatonin 22:690;26:965;30:369 role in circadian rhythmicity 30:369 synthesis of 30:369 Meldrum's acid 1:516;10:282;13:56,67 Meleagris gallopavo 5:836 hemoglobin components of 5:836 Melemelenose A and B 25:869 Melia azedarach 9:502;22:526;26:187; 28:424 phag-inhibitory activity of 26:187 Melia cultivar 26:466 Meliaceae 21:124,127 Meliacin 24:524 as antiviral glycopeptide 24:524 Melicopicine 13:351-354,365,368 synthesis of 13:353,354 Melilotic acid 7:205,206 Melilotus officinalis 23:337;25:93,132 Melinis minutiflora 28:398 c~- and [3-pinene from 28:398 Melinonine F 26:1060 Melionine E 1:125,126 Melionine F 1:127 Melissa 29:581 Melissa officinalis L. 2:404;22:526 callus cultres of 2:404 for epilepsy and hysteria 22:526 Melittin 25:274 (+)-Mellein 15:351 (R)-(-)-Mellein 15:383 (S)-(+)-Mellein 15:383 Mellein 15:406;26:449 biosynthesis of 15:406 Mellein derivatives 15:383-385 Mellettia ferruginea 29:775 Mellilogenin 25:97 Mellilotus-saponin O~ 25:95 Mellilotus-saponin O2 25:97 Mellittia usaramensis 22:526 for convulsions 22:526 Melodienone 9:400 Melodinus australis (F. Muell.) 29:362 Melodinus monogynus 25:276 Melodorum fruticosum 9:399;10:152
Meloidogyne arenaria 26:456 Meloidogyne incognita 26:434,435,437, 439,447-450,460,462,463,466,467, 469,471,473,476,483-493,1289 Meloidogynejavanica 26:429,430,456, 464,466,473,478,482 Meloidogyne spp. 26:428,430,432,437, 481,487 Melon-fly pheromone 3:157-158 Melophlus sarassinorum 28:116 Melosmidine 16:505 Melosmine 16:505 Melospiza lincolnii 5:837 hemoglobin components of 5:837 Melospiza melodia 5:837 hemoglobin components of 5:837 MEM 6:558,559 protection with 6:558,559 MEM ethers 1:558 deprotection TMSC1/NaI 1:558 for alcohol protection 1:558 14-Membered cyclic cembrolides 23:175 9-Membered cyclic sulfide 8:205 14-Membered cyclic triene 8:188 (E,E,E)-triene 8:188 (Z,E, E)-triene 8:188 14-Membered furanocembrolide 23:175 14-Membered macrolides 5:613 erythromycin 5:613 oleandomycin 5:613 15-Membered macrolides 5:613 acumycin 5:613 mycinamicin 5:613 rosaramicin 5:613 10-Membered ring 8:179-186 synthesis of 8:179-186 14-Membered ring 8:26 by keto-aldehyde coupling 8:26 6-to 8-Membered ring expansion 3:95, 96 by reactions of enamines with acetylenes 3:95;96 10-Membered rings 1:570 entry into 1:570 13-Membered thiolactone 8:205 Membrane disruption 22:32
507 Membrane electric potential 21:8 Membranipora membranacea 17:93 Membranipora perfragilis 17:91; 21:265;25:825 MEM-directed organometallic addition 12:201 Memmeisin 19:773 Memory improvement 23:499 Bacopa monniea in 23:499 Menadione 9:391,392,400 Menaquinone- 1 29:736 biosynthesis of 29:736 synthesis of 29:226 [3-Menene 25:131 Meningitis 2:422 due to Candida neoformans 2:422 Menippe mercenatia 19:628 Menispermaceae 21:3 Menoctone 26:803 Menoquinones 26:638 Menorrhagia 22:643 Mental disorders 30:368 role of serotonin (5-HT) 30:368 Mentella genus 7:124,126;19:4;27:375; 29:579 (+)-p-Menth- 1-ene 21:585 p-Menth- 1-ene 29:83 activity in AM assay system 29:83 activity in lung-1 assay system 29:83 p-Menth-8-ene- 1.2,-diol 25:148 Mentha arvensis 21:618;30:207 menthol from 30:207 Mentha haplocalyx 30:219 neolignans from 30:219 Mentha lavandulacea 30:262 kaempferol 3-O-glucosyl(1 3 ) rhamnoside-7-O-glucoside from 30:262 Mentha longifolia 7:119;27:375;30:261 isoorientin from 30:261 longitin from 30:261 vicenin-2 from 30:261 Mentha piperita 25:155;27:375;29:579; 30:207 menthol from 30:207 Mentha pulegium 25:156;27:375
Mentha sp. 21:599;26:746;29:83 Mentha spicata 21:599 Mentha spicata cv. lacinata 7:119 Mentha sylvestris 27:375 (+)-trans-p-Mentha-2,8-dien- 1-ol 19:203 p-Mentha-2,8-diene-l-ol 25:148;29:83 activity in GST assay system 29:83 cis and trans 25:148 p-Menthadienol 19:187 condensation of 19:187 p-Mentha-l,8-diene-4-ol 25:148 p-Menthane-3,8-diol 21:611 1-p-Menthen-6,9-diol 25:145 1-Menthene 25:149 8-p-Menthene- l,2-cis-diol 25:145 8-p-Menthene-l-ol-2-one 25:145,147 p-Menth-l-ene-9-ol 25:138 R-(+)-p-Menthne 16:261 (L)-Menthol 10:684,685 L-Menthol 13:300 from L-menthone 13:299 d-Menthol 14:179 (+)-Menthol 21:585 (-)-Menthol 17:605 (-)-Menthol 21:585 (-)-Menthol 30:207 activity in abdominal constriction test 30:207 activity in hot-plate test 30:207 antinociceptive effect of 30:207 1-Menthol 27:381 (I1R,2S,5R)-(-)-Menthol 6:86,87 in 7,20-diisocyanodociane synthesis 6:86,87 Menthol 13:332,337;21:599,615; 25:125,133,155 ;29:83 ;30:193,207 activity in AM assay system 29:83 activity in Mam-2 assay system 29:83 analgesic properties of 30:207 kappa-opioid receptor activation by 30:207 (+)-Menthol esters 25:155 L-Menthol from 13:305 L-Menthone 13:299
508
(-)-Menthone 21:585;29:83 activity in AM assay system 29:83 Menthone 21:615;27:375 (-)-Menthyl (+)-(R)-p-toluene-sulphinate 10:66 (-)-Menthyl (S)-p-toluene-sulfinate 14:517,518 from p-toluenesulfinic acid sodium salt 14:517,518 with 4- [(tetrahydro-2H-pyran2yl) oxy] butylmagnesium chloride 14:522,523 Menthyl acetate 25:156 DL-Menthyl chloroacetate 25:155 Menthyl diazoacetate 14:684 1diastereomeric 14:684 hydrazone of 14:684 1-(-)-Menthyl ester 4:437 as chiral auxiliary 4:437 Menthyl glyoxalate 12:152 with di-p-anisylmethyl amine 12:152 (-)-Menthyl N-amino carbonate 14:684 (-)-(S)-Menthyl p-toluenesulfinate 4:490 synthesis of 4:490 (-)-Menthyl-(S)-p-toluenesulfinate 19:14 Mentzetriol 7:441,442 [4,6-Meo-ENBPI]Fe(III) complex 25:352 3-MeOSAMM 1 23:3,24 3-MeOSAMM 2 23:3,24 Mepacrine 25:344 4-Mepacrine 26:836 Meranzin 21: 574 2-Mercaptobenzothiazole 25:816; 26:162 synthetic derivatives of 26:162 Mercaptolysis 6:279,280,282-286 Mercaptomethylation 6:323-325 6-Mercaptopurin 25:266 Merck method 12:135 Merck procedure 4:453 for carbapenem formation 4:453 mercuric salt method 4:22 for nucleoside synthesis 4:22 Mercurialis annua 17:117
Mercuric acetate 1:125 oxidative cyclization 1:133 Mercuric amidation 14:568 Mercury (II) triflate 1:657 formation of 1:657 Mercury (II) triflate/N,N-dimethylaniline complex 1:657,658 Mercury (II) trifluoromethanesulfonate 1:656 cationic olefin cyclization 1:656 Mercury group 1:659 replacement by OH group 1:659 Meretrix petechialis 30:400 sulphated [3-galactans from 30:400 Meridian B 25:764 Meridian C 25:764 Meridian D 25:764 Meridian E 25:764 Meridianone 7:233 Meridine 23:275 Meridinol 24:752 synthesis of 24:752 Merkel cell carcinoma 30:308 aloe-emodin effects on 30:308 Meroterpenoids (Me) 29:113 euglobal-G1 as 29:113 Merozoite stage 25:328,329 Merulinic acids 9:317 Merulius sp. 9:317,327,350 3-MeSAMM 1 23:3 Mescaline 22:14;25:531 Mesembrenol 20:234 from Crinum oliganthum 20:234 Mesembrenone 20:234 from Narcissus pallidulus 20:234 Mesembrine 4:3-5 from Sceletium species 4:3-5 retrosynthesis of 4:3,4 synthesis of 4:10-12 (+)-Mesembrine 10:407 synthesis of 16:710 (-)-Mesembrine 10:410,411 enantioselective 10:410,411 total synthesis of 10:410,411 (_)-Mesembrine 13:483,493 synthesis of 13:483,493
509
Mesembryanthmoidigenic acid 7:139, 140 etabolically-active cells 7:114-117 cloning of 7:114-117 selection of 7:114-117 Mesitoylated model compounds 17:268 Mesitylene sulfonyl-3-nitro-triazole (MSNT) 4:271 as condensing agent 4:271 Mesitylene sulfonyl-tetrazol (MSTe) 4:271 as condensing agent 4:271 N-Mesitylenesulfonyltriazole 18:401 Meso-3,4-epoxycyclopentanone 14:510 chiral acetal derivatives of 14:510 diastereodifferentiating isomerization of 14:510 4-hydroxy-2-cyclopentenone acetal from 14:510 Meso-cyclic ketones 14:486 asymmetrization of 14:486 Mesona polustris 24:275 Mesoponera castanea 5:224-227,229, 245,247,254 Mesoponera castaneicolor 5:224-227, 229,245,257,254 Mesoponera sp. 5:224-227,245,247,254 Mesotetro 19:363 (+)-Mesquitol (3,7,3',4'-tetrahydroxyflavan) 29:580 effects on ACE 9 29:580 Messor barbarus 22:81 Mesua ferrea 4:768 coumarins from 4:389,391 Mesua genus 19:768 Mesua thwaitesii 4:389,391 coumarins from 4:389,391 (1S,2R,8S,8aR)-2-O-Mesyl-5-oxo- 1,2,8trihydroxy-indolizidine 12:325 Mesylate elimination 1:477 Mesylation 4:16,126,442;6:9,10,71,76, 77,229,289,290,390,548-550;10:322, 323;19:147,371 axial 1:415,417 of alcohol 19:494 of allylic alcohols 4:16 of primary alcohol 19:477
Mesyloxy eudesmanolides 14:3651~Mesyloxy oxazoline 18:461 3-Mesyloxy-L-threonate 12:17 antiperiplanar 12:17 [3-elimination of 12:17 stereoselective 12:17 (E)-(Z)-T-Mesyloxy-c~,[3-enoates 10:411 (E), (Z)-T-Mes ylo xy-~-alkyl-ot, [3-enoates 10:411 1,3-chirality transfer in 10:411 E-selective 10:411 with organocyanocopper trifluoroborane 10:411 Metabolic activation system 27:303 Metabolic inactivation 27:322 ofabscisic acid 27:322 Metabolism 6:142,143,155,156; 18:523-533 of acetylenic carotenoids 6:155,156 of allenic carotenoids 6:142,143 of brassinosteroids 18:523-533 of 24-epibrassinolide 18:523-533 of 24-epicastasterome 18:523-533 of quassinoids 7:388 ofvitamin D 9:511,512 of vitamin O2 9:513 of vitamin D3 9:514,521 Metabolites 17:4;21:181,187 from fatty acids 21:187,196 from polyketide pathway 21:196, 203 from amino acid pathway 21:218 from isoprenoid pathway 21:226 Metabotropic glutamate receptors 25:531 Metachromin A 15:296;23:212 Metachromin-B 15:296 Metachromin-C 15:296 Metachromin D 18:643 Metacycloprodigiosin 8:272 Metal acetates 11:116 Metal complexes 4:720-722 ofascorbic acid 4:720-722 Metal complexing assays 21:511 Metal enolates 3:409 contact ion pair 14:497
510
from cx,(z-disubstituted ethyl ester 14:497 Metal homeotasis 25:327 Metal reduction 6:541,542 of vic-phenyl thiobenzoate 6:541,542 with sodium naphthalenide 6:541,542 Metal tree porphyrins 25:354,355,356 Metalated arenes 11:140 Metalated sugar 11:140 Metallation 5:822,823 with n-butyllithium 5:822,823 Metallation reactions 4:386-389 in basic media 4:386-389 N,N-disubstituted amides with 4:389 N,N-disubstituted benzyl amines with 4:389 N-Metalloaziridines 1:348,349 2-azaallyl anions from 1:348,349 ring opening of 1:348,349 N-Metalloaziridines 1:348,349 2-azaallyl anions from 1:348,349 ring opening of 1:348,349 Metalloenamines 4:5-7,22 from 2-azadienes 4:7,10-14,17 Metalloendopeptidase 9:500 Metallo-ene reaction 3:21;16:418,437 intramolecular 16:437 Metalloorganic addition 4:124 to a-amino aldehydes 4:124 Metalloporphyrins 25:347 Metalloporphyrins complexes 25:354 Metalloproteases 25:330,331;29:569; 30:836 dipeptidyl carboxypeptidase as 29:569 in angiogenesis 29:570 in embryogenesis 29:570 in inflammation 29:570 in tumor growth 29:570 in wound healing 29:570 a2-macroglobulin inhibition by 30:836 tissue inhibitors of 29:570 Metalloprotoporhyrins 25:357,358 Metallothioneins 25:717
Metal-N402 Schiffbas complexes 25:327 Metamorphosis 21:366;22:376;25:784 Metarhizium anisopliae 12:313;19:486; 27:255 ;28:397,404 control of 28:397 in goats 28:394 in sheeps 28:394 Metarrhizium sp. 21:224 Metastable ion measurements 9:467 Metastasis 19:351;30:64 in liver 30:64 in mice 30:64 of tumors 19:351 Metastatic cells 16:76 Metastatic methylcholanthrene (MC) 23:130 Metastatic secondary tumor 26:221 in animals 26:221 Metastatic tumor cells 30:60,61 in liver 30:60 Metastatic tumor growth 30:69 in liver 30:69 Metastatic tumors 30:64 in LLC-bearing mice 30:64 inhibition of 30:64 Metatrichia vesparium 12:366,370; 29:232 antibiotic properties of 29:232 arcyrialflavin B from 12:366,370 arcyrialflavin C from 12:366,370 vesparione from 29:232 Met-enkephalin 27:802,803 Meth 1 tumor cells 25:432 Meth A 25:433 Meth A fibrosarcoma 28:534 antitumoral effects of 28:534 Meth A tumor 25:432 Meth A tumor cell antigen 25:444 cytotstatic activity of 25:433,434 Meth A tumor growth 25:453 Metha and Mohal 29:462 carbafuranose synthesis by 29:462 carbaaldopyranoses synthesis by 29:470 (R)-Methadone 22:24 [3-Methallyltriphenylstannane 12:478 13-Methallytri-n-butylstannane 12:478
511 Methane sulphonate 6:126,127 DBU reaction with 6:126,127 p-Methane-3,8-diol 25:136 Methanesulfonyl chloride 8:27-30 NZ-Methanesulfonyl CPI 3:325 synthesis of 3:325 Methaniminium methylide 1:336,337 1 H- 1,5-Methano-2,5-benzoxazonine derivaives 6:474 from 10~-methyl-5H-oxazolo [2,3-A] isoquinoline derivatives 6:474 synthesis of 6:483 Methanobacterium thermoautotrophicum 9:606
Methanobenzoxazecines 6:474 synthesis of 6:474 Methano-bridged benzoxazecines 6:483 from isoquinoline derivatives 6:483 synthesis of 6:483 Methanodibenzazocine 6:471 (+)-argemonine from 6:471 5,6-Methanoleukotriene 14:489,490 synthesis of 14:489,490 5,6-Methanoleukotriene A4 1:629 Methanolysis 6:276,390-395;19:42,442; 26:65 acid-catalyzed 14:563,564 alkoxyacrylate from 14:563,564 of (Z)-9-hexadecenoic acid 26:70 of 10-hydroxydecanoic acid 26:65 5-Methdehydropodophyllotoxin 26:194 Methicillin resistance 21:602,604 Methiin 23:458 Methionine 9:606;21:301,304,307,362, 406;22:255 from 5-methyltetrahydrofolate 11:210 Methionine aminopeptidase 22:262 Methionine sulfoxide 9:581 Methionyl-enkephalin 2:21 negative ion LSI mass spectrumm 2:22 positive ion LSI mass spectrum 2:21 3-(Methlthio) propanamine 21:407
Methmycins 13:158 Methoprene 10:152;13:667;22:395 Methotrexate 25:266 Methoxatin 1:163;26:1266 synthesis of 1:170-172 Methoxbipyrrole aldehyde 8:273 synthesis of 8:273 c~-Methoxy alkyl plumbane 16:350 6-Methoxy dihydrochelerythrine (angoline) 14:773-775 11-Methoxy ferruginol methyl ether 14:678-681 to taxodione 14:678-681 transformation of 14:678-681 5-Methoxy podophyllotoxin-4- [3-Dglucoside 26:212 Methoxy pyrazines 5:247-249 8-Methoxy sampangine 23:6 Methoxy thiofurodysinin acetate lactone 25:815 1-(2-Methoxy)naphthylsulfinyl chloride 10:684,685 8-Methoxy- 1,2,3,4-tetrahydroisoquinolines 10:121,122 11 -Methoxy- 12-hydroxyspermostrychnine 26:1064-1066 11-Methoxy- 19(R)-hydroxygelselegine 15:483 from Gelsemium elegans 15:484 Na-Methoxy- 19(Z)-anhydrovobasinediol 15:466,467 12-Methoxy- 19c~,20c~-11,12dimethoxykopsinaline 9:189 12-Methoxy- 19~,20~-epoxyakuammicine 1:36 6-Methoxy- 1-indanone 6:195 6-Methoxy- 1-tetralone 12:235 dihydrospiniferin- 1 derivative from 6:72 3 [3-Methoxy-2,3-dihydrowithaferin A 20:224 1-Methoxy-2,3-methylenedioxybenzene 27:499 1 -Methoxy-2-methylanthraquinone 26:662 trans-4-M e tho x y-2-o xazo li dino ne
12:425
512 chiral synthon of 2-amino alcohol from 12:425 from cycloadduct 12:425 4-Methoxy-2-oxazolidinone 12:426-428, 435,436 acid catalyzed 12:426-428 4-alkyl-2-oxazolidinones from 12:428 4,5-disubstituted-2-oxazolidinones from 12:427,428 from 2-oxazolidione 12:437,438 from Diels-Alder adducts 12:435,436 via-iminium cations 12:426-428 N-deacylated 12:427,428 4-substituted-2-oxazolidinones 12:435-438 substitution of 12:426-428 with organocuprates 12:435,436 4-Methoxy-3-(triisopropylsilyl) pyridine 12:351 10-Methoxy-3,4,5-6-tetradehydrocorynantheol 1:124 2-Methoxy-3-isobutylpyrazines 5:221, 225,247-249,266;13:320 2-Methoxy-3-isopropyl pyrazine 13:320 2-Methoxy-3-isopropyl- 1,4-benzoquinone 14:692,693 from resorcinol dimethyl ether 14:692,693 taxodione from 14:692-695 2-Methoxy-3-isopropyl-pyrazines 5:225,247-249,266 2-Methoxy-3-methylpyrazines 5:225 2-Methoxy-3-sec-butylpyrazines 5:225, 247-249,266 5ct-Methoxy-4,5-dihydrojaborosalctone B 20:223 2-Methoxy-4-hydroxybenzaldehyde 21:741 Methoxy-4-methylsampangine 23:8 8-
(R)-(-)/(S)-(+)-3'-Methoxy-4'-O-methyl
joubertiamine 14:501,502 from chiral enone acetal 14:501, 502 synthesis of 14:501,502 via Claisen Eschenmoser rearrangement 14:501,502
(4E, 7S)-(-)-7-M etho xy-4-tetradeceno ic acid 26:78 total synthesis of 26:78 (Z)-2-Methoxy-5-hexadecanoic acid 26:77 total synthesis of 26:77 (4R,5R)-4-Methoxy-5-phenylseleno-2oxazolidinones 12:421,422 from 3-[ 1S)-2-exo-alkoxy- 1apocamphanecarbonyl]2-oxazolones 12:421,422 5-Methoxy-7-hydroxyphthalide 9:400 2-Methoxy-7-methyljuglone 22:609,610 8-Methoxy-8,10-dihydrogentianine 6:528,529 from Strychnos dinklagei 6:529 spectral data of 6:528,529 6-Methoxy-8-hydroxyflavone 5:640 12-Methoxyabieta-8,11,13-trien- 11-ol 29:99 activity in EBV assay system 29:99 11-Methoxyacronycine 20:792 11-Methoxyakuammicine 1:35 [(Z)-T-Methoxyally] diisophinocamphenyl-borane 21:442 Methoxyamericanolide G 23:161 2-Methoxyanthraquinone 26:662 7-Methoxyaromadendrin 26:802 4'-Methoxyavarone 15:301 4'- O-Methoxybavachalcone 4:378,379 synthesis of 4:378,379 3-Methoxybenzaldehyde 9:343 Methoxybenzene 30:146,149 Birch reduction of 30:146 synthesis from 30:149 6-Methoxybenzoxazolinone 21:690 p-Methoxybenzyl (PMB) ether 30:8 oxidative cleavage of 30:8 p-Methoxybenzyl (pyrichalasin) 15:355 (R)-3-p-Methoxybenzyloxy-2-methylpropionaldehyde 30:10 aldol condensation of 30:10 Methoxybrominations 12:419-421 diastereoselective 12:419-421 of 3-[(IS)-2-exo-alkoxy- 1apocamphanecarbonyl]-2oxazolones 12:420,421
513 of 3 [(IS)-ketopinyl]-2-oxazolone 12:420,421 9-Methoxycamptothecin 5:128 1-Methoxycanthin-6-one 7:389,390,394 Methoxycarbonyl 6:540 as activating group 6:540 1-Methoxycarbonyl pyridinium chloride 6:448 reaction with alkynyl Grignard reagents 6:448 17-(Methoxycarbonyl)-28-nor-isoiguesterine 30:667 1-(M ethoxyc arb onyl)- 2- me thoxypyrroline 12:292 (+)-elacokanine from 12:292 cyclohexen- 1-one 12:25 aldol reaction of 12:25 with TBS ether of glycoaldehyde 12:15 (-)-N-Methoxycarbonyl- 11,12methylenedioxykop-sinaline 9:189 (-)-N-Methoxycarbonyl- 12methoxykopsinaline 9:189 170-NMR of 9:113 [2.2.1 ]-Methoxycarbonyl-7-azabicycloN-heptane 19:78 Methoxycarbonylation 6:547 5-(3'-Methoxycarbonylbutyroyl) aminomethyl-trans-quinolizidine Noxide 15:522 from Sophora tomentosa 15:522 N-Methoxycarbonyl-ethenyl carboxaldimines 4:460 3-Methoxycarbonylpyrrol -2(5H)-one 13:113 from pyroglutamic acid 13:112 cis-p-Methoxycinnamoyl 24:150 trans-p-Methoxycinnamoyl triterpene glycosides 24:150 Methoxycolorenone 21:281 12-Methoxycompactinervine 1:36 7-Methoxycoumarin (herniarin) 9:113, 114;18:976 (Methoxycrotyl) boronic ester 11:424 from (a-chlorocrotyl) boronic ester 11:424 5-Methoxycurcumin 17:364
(24S)-25-(M ethoxy-cycloartanedio 1 (24S)- 25-methoxyc yc loartane- 3 [3,24diol) 29:587 effects on TRY 29:587 5-Methoxydehydrodiisoeugenol 26:226 antibacterial activity of 26:226 7-Methoxydehydronoraporphine 16:516 5-Methoxydehydropodophyllotoxin 26:212 cytotoxicity of 26:212 10-Methoxydeplancheine 9:174 5-Methoxydesoxypodophyllotoxin 18:576 11-Methoxydiaboline 9:189,190 Methoxydidenone 8:169,170 by anodic oxidation of phenols 8:169,170 6' [3-Methoxy-dihydro-scutionin (xB 30:687 ~3C-NMR spectrum of 30:687 2D NMR of 30:687 HRFAB-MS of 30:687 structure of 30:687 9-Methoxyellipticine 22:9 6-Methoxyepicamphor 4:657,658 exo-2-allyl derivative from 4:657,658 Methoxyethoxy group 6:298,299 protection with 6:298,299 3-[(IS)-2-exo-Methoxyethoxy- 1apocamphane-carbonyl]-2oxazolone 12:423 X-ray crystal analysis of 12:423 1-Methoxyficifolinol 28:229 biological activity of 28:229 4'-Methoxyflavanone 9:112 5-Methoxyflavone 22:438 2'-Methoxyflavone 5:14 ~3C_NMR spectrum of 5:14 ~H-NMR spectrum of 5:13,14 3-Methoxyflavone 5:625,626,628,630, 634-636,640 4'-Methoxyflavone 5:653 11-Methoxygelsemamide 15:472,473 from Gelsemium elegans 15:472,473 11-Methoxyhenningsamine 9:189,10
514 (R)-2-Methoxyhexadecanoic acid 26:78 total synthesis of 26:78 4-Methoxyhonokiol 26:232 Na-Methoxyindole 15:497 Methoxyisoquinolinedione 21:285 11-Methoxyisoretuline 1:38,39 11-Methoxykoumine 15:501 7S, 8R, 8' R-(-)- 5-M etho xylari cires ino14,4'-bis-O-13-D-glu 26:199 Methoxylated arylpyruvic acids 30:221 reaction of 30:221 Methoxylated arylpyruvic acids 30:221 reaction of 30:221 Methoxylation 1:247 anodic 1:247 Methoxylimatine 1:40 11-Methoxylimatine 1:40 13[3-Methoxylupanine 27:269 10-Methoxymacrocarpamine 13:393 10-Methoxymacrocarpamine N-4-oxide 13:393 3-Methoxymaleimide 21:415,416 5-Methoxymelicopicine 13:364 6-Methoxymellein 15:384 from Sporormiafungi 15:384 5-Methoxymellein 9:288,289 6-Methoxymellein-O-methyltransferase 25:506,507,508 Methoxymercuration-demercuration 1:510 p-Methoxymethoxyacetophenone 21:742 Methoxymethyl group 6:282,283 protection with 6:282,283 ( S)-(-)- 2-Methoxymethyl- 1-trimethylsilyl-aminopyrrolidine (TMSSAMP) 22:286 1-Methoxymethyl-6-oxo-6H-anthra [1,9-bc]thiophene 25:831 1-Methoxymiller-9Z-enolide 29:89 activity in NFkB assay system 29:89 7-Methoxymitosene 13:445,446 Wender synthesis of 13:445,446 2-Methoxy-N,N-diethylbenzamide 5:827,828 lithiation of 5:827,828 12-Methoxy-Na-methylvoachalotine 5:128
12-Methoxy-N4-methylvoachalotine ethyl ester 5:128 11-Methoxy-N-methyl dihydropericyclivine 13:386 5-methoxynormelicopicine 13:364 7-Methoxynogarene 14:78 N-Methoxy-norcepharadione-A 20:480 12-Methoxy-nor-C-fluorocurarine 1:36 11-Methoxy-O-acetylisoretuline 9:189 Na-Methoxyoxindoles 15:497 1-Methoxyphaseollidin 28:243 anti-Helicobacter pylori activity of 28:243 biological activity of 28:229 2-(4-Methoxyphenoxy) propanoic acid 15:36 Methoxyphenyl 30:213 demethylation of 30:213 2-Methoxyphenyl acetones 30:222 cyclisation of 30:222 2,4-bis (4-Methoxyphenyl)1,3,2,ks,4,)~5-dithiadiphosphetane2,4-dithione 12:301 2-(2-Methoxyphenyl) 1-(methoxyphenyl) ethanone 30:223 structure of 30:223 (S)-Methoxyphenylacetic acid 25:813 2-Methoxyphenylacetones 30:218 products of 30:218 2-Methoxyphenylpyruvic acid 30:221 reaction with boron tribromide 30:221 6-Methoxypipecolate 13:474,475 5-Methoxypodophyllotoxin 26:193 5'-Methoxypodorhizol 18:559,566 from Hernandia cordigera 18:561 8-Methoxyprotoberberinphenolbetaine s 1:190-192 synthesis of 1:190-192 11-Methoxy-rankindine(humantenirine) 9:196,197 11-Methoxyretuline 1:38,39 3-Methoxysampangine 23:3,6,4,45 9-Methoxysampangine 23:7 30-Methoxyscillatoxin D 18:294 synthesis of 18:294-309
515 Methoxyselenylations 12:421,422 of 3- [-2-exo-alkoxy- 1apocamphanecarbonyl]-2oxazolone diastereoselective 12:421,422 Methoxysiloxyfuran 13:452 3-Methoxyspermostrychnine 26:1064-1066 Methoxystapandrone 22:637,638 2Methoxy-substituted dihydrocinchonamine 25:28 3-Methoxytabernaelegantine 5:129 16-Methoxytabersonine 1:68-70 synthesis of 1:68-70 (21)-11-Methoxytabersonine 4:35 conversion to vindoline analogues 4:35 11-Methoxytabersonine 9:193 3-Methoxytanapartholide 27:585 5-Methoxytetralone 15:245 4-Methoxytoluene 12:22-24 Birch reduction of 12:22-24 11-Methoxytubotaiwine 1:40 8-Methoxyumbelliferone 4:378,381 apigravin from 4:378,381 10-Methoxyvellosimine 13:386 10-Methoxyvillalstonine 13:392 10-Methoxyvillastonine-N-4 oxide 13:392 12-Methoxyvoaphylline 5:124 Na-Methoxyyohimbine 15:497 (+)-c~-Methoxy-c~- trifluoromethylphenyl-acetylimide 12:483 (R)-(+)-c~-Methoxy-c~-(trifluoromethyl) phenyl acetyl chloride [(+)MTPAC1] 14:557,558 MTPA esters from 14:557,558 (R)-(+)-c~-Methoxy-c~-(trifluoromethyl) phenyl acetylesters 14:557,558 from piperidine derivatives 14:557,558 sythesis of 14:557,558 Methuenine 5:123 Methuenine-N-oxide 5:126 3-Methybutylaminodihydroisocoumarins 15:388 N-Methylated systemin derivative 25:376
Methyl 18-carboxy-labda-8,13-(E)diene-15-oate 25:260 Methyl 4-(methylthio) butyldithiocarbamate (MBDC) 26:1081,1082 Methyl (2E)-2,4,5-tetradecatrienoate 10:153 Methyl (2E,4E)-2,4-nonadienoate 10:166 synthesis of 10:166 Methyl (2Z,4Z)-2,4-decadienoate 10:152 Methyl (9-methoxycarbonylnonyl) triphenyl phosphonium bromide 26:65 Methyl (methyl 4-deoxy-[3-L-arbinohexopyranoside)uronate 14:172 from methyl (methyl-4-deoxy-[~L-arabino-hexopyranoside) uronate 14:172 Methyl (methyl 4-deoxy-[3-L-threo-hex4-enopyranoside)-uronate 14:172 methyl (methyl 4-deoxy-~-Larabino-hexopyranoside) uronate from 14:172 Methyl (R)-et-hydroxyphenylpropionate 12:480 (3R,4S)-statine from 12:480 Methyl (S)-3-hydrox-2-methyl propionate 12:155 from isobutyric acid 12:155 Methyl (triphenylphosphoranylidene) acetate 12:488 Methyl (Z)-2-methoxy-6-hexa decenoate 26:75 total synthesis of 26:75 Methyl 11-methylpentadecanoic acid 26:64,65 Methyl 12,13-epoxy-trans-communate 29:101 activity in EBV bioassay system 29:101 Methyl 15,16-bisnor-13-oxolabda-8(17), 11E-dien- 19-oate 29:101 activity in EBV bioassay system 29:101 Methyl 15-hydroxy-7-oxo-dehydroabietate 29:99
516 activity in EBV assay system 29:99 Methyl 15-hydroxy-8,12a-epidioxyabiet- 13-en- 18-oate 29:99 activity in EBV assay system 29:99 Methyl 15-hydroxy-8a, 14a, 12a, 13a-diepoxyabietan-18-oate 29:99 activity in 29:99 Methyl 1-deoxynojirimycin derivatives synthesis of 7:42 Methyl 1-propenethiosulfinate-(E) 23:467 Methyl 2,3,4-tri-O-benzyl-a-Dglucopyranoside 13:200 Methyl 2,3,4-tri- O-benzyl-[3-Dglucopyranoside 8:365 thermal glycosidation of 8:366 Methyl 2,3,6-tri-O-acetyl-4-S-(2,3,4,6tetra-O-acetyl-[3-D-galactopyranosyl)-4-thio-a-Dgalactopyranoside 8:335 synthesis of 8:335 Methyl 2,3,6-tri-O-benzoyl-4-deoxy-Dxylo-hexopyranoside 14:158,159 synthesis of 14:158,159 Methyl 2,3,6-tri-O-benzoyl-4-deoxy-aD-xylo-hexopyranoside 14:168 Methyl 2,3,6-tri-O-benzoyl-4-Otrifluoromethyl-sulfonyl-a-Dgalactopyranoside 8:330-334 Methyl 2,3,6-tri-O-benzoyl-a-Dgalactopyranoside 14:168 Methyl 2,3,6-tri-O-benzyol-4-O(trifluromethane-sulfonyl)-[3-Dgalactopyranoside 14:164,165 synthesis of 14:164,165 Methyl 2,3-anhydro-4,6- O-benzylidenea-D-mannopyranoside 12:314 Methyl 2,3-dimethoxy-7-oxo-7Hbenzoc ycloheptene-6,8- dic arborylate 9:225 Methyl 2,3-di-O-acetyl-4,6-Obenzylidene-a-D-galactopyranoside 14:171 Methyl 2,3-di-O-acetyl-4-O-benzoyl-6deoxy-a-D-galactopyranoside 14:171
Methyl 2,3-di-O-acetyl-6-O-benzyol-4deoxy-ot-D-xylo-pyranoside 14:171 Methyl 2,3-di-O-benzyl-4-deoxy-a-Dxylo-hexopyranoside 14:153 synthesis of 14:153 Methyl 2,3-di-O-benzyl-4-deoxy- [3-Lthreo-hex-4-enopyranoside derivative 14:173 Methyl 2,3-O-isopropylidene-a-Dmannopyranoside 14:152 Methyl 2,6-di-O-methyl-3,4- Othiocarbonyl-[3-D-galactopyranoside 14:158 from D-galactose 14:158 Methyl 2-arylpropanoates 14:158 synthesis of 6:323 Methyl 2-azido-4,6-O-benzylidene-2deoxy-a-D-altropyranoside 12:327 Methyl 2-azido-4,6-O-benzylidene-3deoxy-a-D-altropyranoside 12:348 6,7-dihydroxyindolizidine from 12:348 6,7,8-trihydroxyindolizidine from 12:348 Methyl 2-chlorocyclopropylidene acetate 8:419 Methyl 2-propenethiosulfinate 23:467 Methyl 3,3-dimethylacrylate 8:410 Methyl 3,4,6-tri-2-amino-2-deoxyglucopyranoside 14:189 Methyl 3,4-anhydro-a-Dgalactopyranoside 13:237 Methyl 3,4-dideoxy-a-D-erythro-hex-3enopyranoside 10:419 from methyl a-Dglucopyranoside 10:419 Methyl 3,4-O-(dibutylstanyl)-a-Larabinofuranoside 6:363 Methyl 3,5-dimethyl benzalmalonate 9:225 Methyl 3,5-dimethylbenzoate 9:224 Methyl 3,6-di-O-pivaloyl-a-Dmannopyranoside 14:166 photo-induced reduction of 14:166 Methyl 3-acetamido-2,4,6-tri-O-acetyl3-deoxy-a-D-mannopyranoside 12:315
517
Methyl 3-acetamido-2-O-acetyl-3deoxy-4,6-Di-O-mesyl-a-Dglucopyranoside 12:326,327 (-)-1,8 dl-epi-swainsonine from 12:326,327 Methyl 3-acetamido-2-O-acetyl-4,6-Obenzylidene-3-deoxy- a,Dglucopyranoside 12:326 (-)-8-epi-swainsonine from 12:326 Methyl 3-amino-3-deoxy-a-Dmannopyranosidehydrochloride 12:314 Methyl 3-deoxy-4,6-O-benzylidene-Dlyxo-hexopyranoside 14:167 synthesis of 14:167 Methyl 3-deoxy-a-D-arabinohexopyranoside 14:180 (S)-(+)-Methyl 3-hydroxy-2-methylpropionate 30:17 (+)-discodermolide 30:17 in synthesis of 30:17 role in (-)-pironetin synthesis 30:30 (R)-Methyl 3-hydroxybutyrate 4:462, 463,465,475 dianion of 4:562 Methyl 3-hydroxypentanoate 1:693,708 as chiral building block 1:693,708 pheromones synthesized from 1:708 Methyl 3-O-carbamoyl-2-deoxy-[3-Drhamnoside 5:598 Methyl 3-tert-butoxy-carbonyl-2-oxooxazolidine-4-carboxylates 12:430 with cesium carbonate 12:430 N-boc-2-aminoacrylate from 12:430 a-Methyl 3-ulosonates 30:459 stereoselective formation of 30:459 Methyl 3 [3-hydroxyfriedelan-29-oate 7:168 (Z)-Methyl 4-(methylthio)-3-butenyl dithio-carbamate 26:1081 Methyl 4,4'-dithiocellotrioside 8:344, 346 acetolysis of 8:344,346
(+)-Methyl 4,6-O-benzylene-a-Dglucopyranoside 30:30 role in (-)-pironetin synthesis 30:30 Methyl 4,6-O-benzylidene 2,3,6,2',3'penta-O-benzyl-[3-maltoside 14:160 Methyl 4,6-O-benzylidene-2,3-di- Otosyl-a-D-glucopyranoside 14:145 selective reduction of 14:145 Methyl 4,6-O-benzylidene-2,3-Othiocarbonyl-a-D-glucopyranoside 14:158 Methyl 4,6-O-benzylidene-2-deoxy-~-
D-erythro-hexopyranoside-3-ulose
10:421 Wittig olefination 10:421 Methyl 4,6-O-benzylidene-2-O-tosyl- ~D-glucopyranoside 14:156 Methyl 4,6-O-benzylidene-3-O-benzyl2-deoxy-c~-D-ribohexopyranoside 6:282,283 from D-glucose 6:282,283 Methyl 4-deoxy-2,3-di-O-methyl-c~-Dxylo-hexopyranoside 14:157 Methyl 4-deoxy-2,6-di- O-methyl- [3-Dxylo-hexopyranoside 14:158 Methyl 4-deoxy-D-lyxo-hexopyranuronate 14:143 Methyl 4-deoxy-[3-L-arabinohexopyranoside 14:172 Methyl 4-O-triflylgalactoside 8:330-335,343 Methyl 4-S-[3-D-galactopyranosyl-4thio-a-D-galactopyranoside 8:335 Methyl 5'- hydroxyepijasmonate 6:557 Methyl 5-acetamido-4,7,8,9, tetra-Oacetyl-3,5-dideoxy-2-thio-D-glycero-
a-D-galacto-2-nonulopyranosonate
8:340,341 Methyl 5-O-benzyl-4-deoxy-D-lyxohexonate 14:182 Methyl 6-O-benzoyl-2,3-O-isopropylidene-a-D-mannopyranoside 14:158 Methyl 6-O-benzoyl-2,3-O-isopropylidene-a-D-talopyranoside 12:316 Methyl 6-thiogentiobioside 8:337,338
518
Methyl 6-thio-c~-D-glucopyranoside 8:337,338 Methyl 6c~,7c~-dihydroxyvouacapan1713-oate 29:103 activity in AOS bioassay system 29:103 Methyl 9-deoxy-9-oxo-c~-apopicropo dophyllate 26:195 Methyl acarviosin 13:280,240-244 Methyl acetoacetate 13:72,73 hydrogenation of 13:72,73 a-Methyl aldehyde 12:48-53 from levoglucosan 12:45 Methyl anacardate 9:337 Methyl anagolensate 9:94 Methyl aplysinopsin 5:410 antidepressant activity 5:410 N-Methyl ascorbigen 4:725 exo-Methylation 4:655,658,659 of camphor 4:658,659 of camphor derivative 4:658,659 Methyl benzalmalonates 9:224,227 Methyl bigutol 21:205 Methyl bixin 20:602 (9Z)-Methyl bixin 20:602 N-Methyl bromoeudistomin D 23:266 1-Methyl camphene 4:649 from fenehone 4:649 (-)-4-Methyl camphor 4:650-652 C(3)-methylation of 4:657,658 optical purity of 4:652 3-endo-Methyl camphor 4:656-658 bromination of 4:656-658 by C(3)-methylation of camphor 4:657,658 3-exo-Methyl camphor 4:657,658 by C(3)-methylation of camphor 4:657,658 Methyl carbenoid 14:488 asymmetric cyclopropanation with 14:488 Methyl cis-(4S,5S)-5-methyl-3-tertbuto x ycarbon yl-2-oxo-o xazo lidine4-carboxylates 12:430 N-boc-L-allo-threonine methyl ester from 12:430 Methyl cis-3,4-dimethoxycinnamate 9:219,220,223,226,228
Methyl cis-ferulate 9:219,220,226,227 S-Methyl cysteine (SMC) 458,468 N-Methyl cytisine 26:487 Methyl dehydroabietate 29:99 activity in EBV assay system 29:99 Methyl dihydroepijasmonate 6:557 (+)-Methyl dihydroepij asmonate 6:558,559 synthesis of 6:558,559 S-Methyl dithiocarbonate 14:157 from di-O-isopropyliden glucofuranose 14:157 Methyl dithiocarbonates 14:160 from 1,2,5,6-di-O-isopropylidene-D-hexofuranose s 14:160 N-Methyl ekeberginine 2:118,119 13C-NMR of 2:120 Methyl ent- 13-hydroxykaur- 15-en- 19oate 29:101 activity in EBV bioassay system 29:101 (-)-N-Methyl ephedrine 4:326 resolution with 4:326 (+)-Methyl epijasmonate 6:558,559 synthesis of 6:558,559 Methyl epijasmonate 6:558-559; 8:152-155 plant growth inhibitor 8:140 Methyl ester 13:29,30;27:346 pentalenolactone E 13:29,30 pentalenolactone P 13:30-32 8',8',8'-trifluoro-ABA from 27:346 l'-Methyl ether 27:341 ABA of 27:341 Methyl ether ferruginol 14:668,670,676 Methyl eugenol 5:473 Methyl farnesoate 22:401 4-Methyl fentanyl 30:199 structure of 30:199 Methyl furanosides 1:404,405 Methyl glycookadaate 5:385,388 Methyl glyoxal synthase 11:208 Methyl Grignard reagent 19:208 R-(+)-3-Methyl hexadecane-dioate 8:224,225
519
(-)-2-Methyl isoborneol 4:650,651 acid catalysed rearrangement of 4:650,651 ent-Methyl isocopolate 6:56,57 from (+)-manool 6:56,57 in (+)-isoagatholactone synthesis 6:56,57 N-Methyl isocorydine 24:856 neuromuscular blocking action of 24:856 Methyl jasmonate 6:557;7:484;8:140; 27:60 partial synthesis of 7:485 pheromone activity of 8:153 synthesis of 8:152-155 (+)-O-Methyl joubertiamine 10:408 O-Methyl jubertimine 4:3-5,6-10 from Sceletium species 4:3,4 retrosynthesis of 4:4,5 synthesis of 4:8-10 N-Methyl julifloridine 9:70,77 Methyl ketones 11:130;29:366 anti-angiogenic properties of 29:369 as tubulin polymerization inhibitor 29:366 Claisen condensation of 11:130 effects on tumor vasculature 29:366 from ester 11:130 synthesis of 11:130 c~-Methyl ketoside 30:427 as substrate 30:427 Methyl labda-8(17), 13-dien- 15,12Rolid- 19-oate 29:101 activity in EBV bioassay system 29:101 Methyl L-arabino pyranose 7:155 from L-arabino pyranose 7:155 from L-arabinopyranosyl 3[3acetyl oleanotate 7:155 Methyl L-aspartyl-2 -aminocyclopentanecarboxylate 22:298 Methyl lycaconitine 25:528 Methyl malonate 13:79 alkylation of 13:79 Methyl malonic acid 13:69 Methyl methylthiomethyl sulfoxide 6:309-325
preparation of 6:309-325 Methyl methylthiomethylsul fone 6:309,325-328,332 synthesis of 6:326 Methyl nuapapuanoate 9:18,19,23 stereochemical revision of 9:19 Methyl okadaate 5:385,388 Methyl peracetyl et-hikosaminide 1:413-416 synthesis of 1:413-416 Methyl perillate 6:545 (+)-Methyl phaseate 6:559,560;16:245 synthesis of 6:559,560 Methyl phenacyl- 1,1-dimethylprop-2enylmalonate 5:759 Methyl phosphonates 13:271-281,287, 290 by phosphoramidite method 13:272 by phosphotriester method 13:272 diastereoselective synthesis of 13:279,280 c~-Methyl piperidine 14:572,573 6-c~-Methyl prednisolone 9:428,429 Methyl protodioscin 23:824 (R)-(+)-Methyl p-tolyl sulfoxide 10:679-685 N-Methyl putrescine 22:724 Methyl pyrazines 5:222,234-236,267 mass spectrometry of 5:267 Methyl reserpate 9:174 Methyl salicylate 28:406 acaricidal properties of 28:406 Methyl salicylate 28:406 acaricidal property of 28:406 7-O-Methyl scutellarein 21:690 N-Methyl secodine 5:188,190 synthesis of 5:188,190 1,2-Methyl shift 6:48 (+)-A9(12Lcapnellene from 6:48 in (+)-africanol 6:37 2,3-exo-Methyl shifts 4:633,634,639, 643 in camphor derivatives 4:633, 634,639,643 in rearrangement of camphor 4:626,627
520
2,3-endo-Methyl shifts 4:638,639
(-)-Methyl shikimate 16:674 synthesis of 16:674 4-Methyl sterols 25:56 Nb-Methyl strictamine 9:195 ~H-NMR spectrum of 5:152 mass spectrum of 5:152 NOE difference measurements 5:152 UV spectrum of 5:152 24-Methyl thornasterols A 15:48 Methyl trans-(4S,5R)-5-Methyl-3-tertbutoxycarbonyl-2-oxo-oxazolidine4-carboxylates 12:430 N-boc-L-threonine methyl ester from 12:430 Methyl trans-3,4-dimethoxycinnamate 9:223 Methyl trans-4-methoxy-2-oxo-3butenoate 14:179 (+)-Methyl trans-chrysanthemate 16:242 synthesis of 16:242 Methyl transferases 9:592,598,601, 603-605 S-adenosylmethionine dependent 11:208 Methyl tri- O-benzyl-6-bromo-a-Dglucopyranoside 12:331 from methyl-c~-Dglucopyranoside 12:331 3'-Methyl tyrosine 10:106 Methyl vinyl ketone 14:559 cx-keto acetal with 14:510 Methyl c~-(phenylsulfonyl) acetate 10:12 Methyl c~,L-rhamnopyranoside 6:287, 288 Methyl (x-2-thiosophoroside 8:328 synthesis of 8:328 Methyl c~-ketocarbothioates 6:335Ssynthesis of 6:335 Methyl ot-L-mycaminoside 4:148 synthesis of 4:148 Methyl (x-peracetyl hikoseminide 11:449-451 synthesis of 11:449-451 Methyl [3-cellobioside 7:51,52,56,64-66
Methyl ~-D-gentosaminide 14:50 Methyl [3-D-glucopyranoside 15:431 Methyl [3-gentiobioside 7:52 kinetic parameters of 7:52 Methyl [3-1actoside 7:52,54 kinetic parameters of 7:52,54 Methyl 7-oxosenecioate 6:8 in (~)-ireinianin synthesis 6:8 Methyl n-tolyl 27:752 of sulfoxidation 27:752 3-O-Methyl-(+)-catechin 22:429,442, 443,445,446 Methyl-(E)-3-acetoxyacrylate 11:306, 307 Diels Alder reaction of 11:306, 307 with isoprene 11:306,307 S-Methyl- 1-7-glutamylcysteine 23:458 Na-Methyl- 1,2-dehydrostrictamine 9:183 (R)-2-Methyl-l,3-butane diol 12:160, 161 sulfur analogue of 12:160,161 2-Methyl-l,3-cyclohexadione 6:19 reaction with ethylvinyl ketone 6:19 Robinson annulation of 6:19 trimethyl decalone from 6:19 2-Methyl- 1,3-cyclopentanedione 13:27 2-Methyl-l,6-dioxaspiro [4.5] decane 14:526,527 from (S)-malic acid 14:526,527 from Paravespula vulgaris 14:526 isomers of 14:526-531 synthesis of 14:526-531 (15R)-15-Methy!-12-epi-PGF2[3 7:484 (15 R)- 15-Methyl- 12-epi-prostaglandin F213 7:484 ll-Methyl-12-octadecenoic acid 26:69 total synthesis of 26:69 N~-Methyl- 16-epi-affinine 5: 77,124 (+)- 10-O-Methyl- 18,19-dihydrohunterburnine 14:706-708 from (+)- 18,19-dihydrohunterbumine 14:706-708 synthesis of 14:706-708 1-Methyl-l-phenyl cyclohexane 8:7
521 1-Methyl- 1-phenyl-2-(methylseleno) methyl 8:7,8 cyclopentane 8:7,8 cyclization of 8:7,8 synthesis of 8:7,8 3-(5-Methyl-2 furyl) propionaldehyde 6:445,446 ( 5Z, 8E)- 2-hep tyl- 5-me thylp yrrolizidine from 6:445,446 2-Methyl-2-(4-methylpent-3-enyl)-2Hchromen-6-ol 10:248 Na-Methyl-2,16-dihydroakuammicine 1:35 3-O-Methyl-2,3-dihydroluteolin 25:541 24-Methyl-25,26-dihydroxy-steroids 15:84-86 absolute configuration of 15:84-86 24-Methyl-26-hydroxy and 24-methyl26-oic-steroidal side chains 15:81-84 absolute configuration of 15:81-84 Methyl-2-acetamido-4,6-O-benzylidene2-deoxy-c~-D-glucopyranoside 6:386 O-alkylation of 6:386 with S,R-2-chloropropionic acid 6:386 3-Methyl-2-butenoic acid 25:133 Methyl-2-deoxy- [3-erythro-pentopyranoside 6:362 6-Methyl-2-heptanone 26:65 Wittig reaction of 26:65 7-Methyl-2-heptanone 26:65 Wittig reaction of 26:65 5-Methyl-2-hexanone 26:66 Wittig reaction of 26:66 3-Methyl-2-hydroxoindolizidines 12:284 (S)-N-Methyl-2-hydroxysuccinimide 8:140 6-Methyl-2-1ithio-2-phenyl-6-heptane 8:13 Methyl-2-methoxy-6-(hexa-2,4-diynyl) benzoate 9:317 7-Methyl-2-methylseleno-2-phenyl-6octene 8:9,10 synthesis of 8:9,10
2-Methyl-2-nitrosopropanol 9:573 3-Methyl-2-norbomanone 8:146,147 3-Methyl-2-oxo-indolizidine 12:284 from ethyl 2-[ 1-ethoxycarbonyl methyl) piperidinyl) propanoate 12:284 6-(4-Methyl-2-oxopenlyl) dihydrochelerythrine 27:167 6-Methyl-2-phenyl-6-heptene 8:10 cyclization of 8:10 6-Methyl-2-phenyl-6-1ithio-2-heptane 8:13 2-Methyl-2-vinyl tetrahydrofuran-5-one 25:140,141 Nb-Methyl-213-1613-dihydroakuammicine Na-methochloride 1:35 5-Methyl-3-(2-methylbutyl)-2-(E-3methylpent- 1-enyl)-pyrazines 5:226,230,242-244,262-264 5-Methyl-3-(2-methylbutyl)-2-(Z-3methylbut- 1-enyl)-pyrazines 5:226,230,242-244,262-264 N-Methyl-3-(3-chloro-4,5-dihydroxyphenyl)-3-hydroxyalanine 15:347 Methyl-3,4-dimethoxybenzalmalonate 9:225,226 4-Methyl-3,5-bis(3-trifluoromethylphenyl)pent-2-en-3-one 30:218 Methyl-3,6-dio xo-4-doc o seono ate 23:211 1-Methyl-3-acyl-5-hydroxymethyl-2,4dione 13:548 2-Methyl-3-buten-2-ol 4:377 in coumarin synthesis 4:377 C-prenylation by 4:375-482 2-Methyl-3-buten-2-yl acetate 11:130 decarboxylation of 11:130 2-Methyl-3-buten-2-yl-ester 11:129 (3S,4S)-4-Methyl-3-heptanol 1:681,682; 11:415 from (R,R)-diisopropylethanediol propylboronate 11:415 from (S)-pinane diol propyl boronate 11:412,413 from Scolytus multistriatus 11:142 synthesis of 11:412,413,415 (3R,4S)-4-Methyl-3-heptanol 11:415, 416
522 from (S,S)-diisopropylethan diol methyl boronate 11:415,416 from Leptogenys diminuata 11:415,416 synthesis of 11:415,416 (E)-4-Methyl-3-hexenoic acid 25:140 (S)-M ethyl-3 -hydroxy-2-methylpropionate 21:391 2-Methyl-3-hydroxy-piperidine 9:70 1-Methyl-3-indolylacetic acid 12:381 with 1-methylindole-3-glyoxylylchloride 12:381 5-Methyl-3-isopentyl-2-(E-3-methylbuten- 1-enyl)-pyrazines 5:226,230, 242,244,262 5-Methyl-3-isopentyl-2-(Z-3-methylbuten- 1-enyl)-pyrazines 5:226,230, 242-244,262 5-Methyl-3-n-propyl-2-(E- 1-butenyl)pyrazines 5:226,242-244,262,264 5-Methyl-3-n-propyl-2-(Z- 1-butenyl)pyrazines 5:226,242-244,262 7-Methyl-3-oxo-6-octenoic acid 25:134 3,4 (4-Methyl-3-pentenyl)-3-butenolide 25:134 2-Methyl-4-isopropyltetronic acid 10:260,261 2-Methyl-4-nitrophenol 21:166 3-Methyl-4-oxoadipate 8:298,299 1-Methyl-4-phenyl- 1,2,3,6-tetrahydropyridine 27:283;28:184 dopaminergic neurotoxicity of 28:184
1-Methyl-4-piperidone 21:132 2C-Methyl-4ot-carba-p-D-arabinoaldofuranose 29:459 carbafuranose synthesis of 29:459 4-Methyl-5 (1-hydroxyethyl) nicotinic acid 6:527 7-O-[4-Methyl-5-(1-hydroxyethyl) nicotinoyl] strychnovoline 6:522, 527 from Strychnos dinklagei 6:522, 527 spectral data of 6:526,527 5-(-)-Methyl-5,6-dehydrocamphor 16:144
(R)-22-Methyl-5,9-octacosa-dienoic acid 26:87 total synthesis of 26:87 2-Methyl-5-alkylresorcinols 21:592 6-Methyl-5-heptane-2-one 25:134 6-Methyl-5-heptanoic acid 25:133 (S)-(+)-6-Methyl-5-hepten-2-ol 25:143 6-Methyl-5-hepten-2-one 25:136,138, 140,143,144,145,165,166 6-Methyl-5-heptenone 25:163 (R)-4-Methyl-5-hexenoic acid 11:260 from (R)-citronellol 11:260 10[3-Methyl-5H-oxazolo [2,3-A] isoquinoline derivatives 6:474 ~H-1,5-methano-2,5-benzoxazonine derivatives from 6:474 (Z)-2-Methyl-5-isopropylhexa-2,5-dien1-al 25:152 Methyl-5-metliylthio-3-oxopentanoate 25:845 1-Methyl-5-thiol-L-histidine disulfate 25:814 (24R)-24-Methyl-5 a-cholestan-3-one 25:419 24-M ethyl- 5~-cho lest- 22(E)- ene313,6ct,8,1513,1613,28-hexaol 15:79 3-Methyl- 6-(3-methyl- 1-azulenyl)1(6H)-azulenone 14:335 7-Methyl-6(E)-hexadecenoic acid 26:71 total synthesis of 26:71 2-Methyl-6-alkyl- 1-piperideine 6:424-426 in Solenopsis xylonio 6:422 2-Methyl-6-methylen-7-octen-2-ol 25:131 2-Methyl-6-methylisoquinoline3,5,8(2H)-trione 25:825 7-Methyl-6-octadecenoicacid 26:72 total synthesis of 26:72 2-Methyl-6-vinyl-pyrazine s 5:222,239 4-Methyl-7,11-heptadecenoic acid 21:189 4-Methyl-7-isopropyl- 1-azulenecarboxylic acid 14:328 4-Methyl-8-methyoxysampangine 23:6 6-Methyl-9-heptadecenoic acid 21:189 Methylacarviosin 22:177
523 R-(+)-3-Methyladipic acid 15:229 11,15-bis-nor-Methylallopurniliotoxin 12:267,298 Methylamine dehydrogenase 9:582 X-ray crystal analysis of 9:582 N-Methyl-anhydroschumannificine 21:143 2-Methylanthraquinone 26:363,374 7-O-Methylapigenin 25:541 Methylarctigenin 5:525 N-Methylarcyriaflavin A 12:378 aglycone of AT2433-B~ and B2 12:378 from cyclohexene imides 12:378 synthesis of 12:377-379 N-Methylarcyriarubin A 12:375,376 acid catalyzed rearrangement of 12:383 arcyriarubin A from 12:375,376 arcyrin/arcyrinin model compounds from 12:383 N-methylarcyriaverdin C from 12:375,376 N-methyldihydroarcyriarubin A from 12:375,376,383 N-Methylarcyriarubin B 12:375,376 arcyriarubin B from 12:375,376 N-Methylarcyriaverdin C 12:376 from N-methyl arcyriarubin A 12:376 [3-Methylaspartate 26:1225 Panek's synthesis of 26:1225 (+)-[3-Methylaspartic acid 14:102 ~-Methylaspartic acid 14:105 Na-Methylaspidospermatidine 1:40 11-O -Methylatalphillidine 13:356,357 fromAtalantia ceylanica 13:348, 349 N-Methylated ant alkaloids 6:435,443 by reductive N-mehylation 6:435,443 synthesis of 6:435,443 Methylated fatty acids 26:63,64 Methylation 19:134 chemoselective 19:92, deoxygenative 19:519 Hakamori method 2:336
with trimethyl orthoformate 1:448,449 N-Methylation 6:478,491,492;19:321 of 1,4-dideoxy- 1,4-imino-Lallitol 7:41-43 of indolines 4:79 O-Methylation 6:76,77 of coumarins 5:516-520, of lignans 5:525-532 in (• synthesis 6:76,77 C-Methylation 7:207 in Artemisia austriaca 7:207 [3-Methylation 8:192,193 p-Methylbenzene sulfinates 14:736 menthyl esters of 14:736 quinolizidine from 14:736 (+)-(R)-ot-Methylbenzylamine 22:281 R-(+)- o~-Methylbenzylamine 4:438 as chiral auxiliary 4:438 (-)-c~-Methylbenzylamines 13:191 (R)-c~-Methylbenzylammonium salt 12:27,28 25-Methylbrassinolide 19:477 6-(3-Methylbut-2-enyl) narigenin 4:378,381 synthesis of 4:378,381 (S)-2-Methylbutanol 13:77 synthesis of 13:77 2-Methylbutyl acetate 25:129 3-Methylbutyl acetate 25:129 3-Methylbutylamino derivatives 15:382 Methylbutylamino-3,4-dihydroisocoumarin 15:381 (S)-2-Methylbutyric anhydride 11:369; 13:558 S (-)-3-Methylbutyrolactone 16:344 Methylbuxene 2:207 N-Methylcaaverine 3:426 Methylcaconitine 21:52 11-O-Methylcaesalpin 5:22,23 13-epi- 11-O-Methylcaesalpin 5:22,23 1[3-Methylcarbapenems 12:159-177; 13:84 by C4-alkylations 12:159-177 by methylation of thienamycin 12:148-150 by reduction of exomethylene
524 group 12:150-154 from amino acid 12:155-159 key intermediates 12:145-177 synthesis of 12:145-177 Methylcardols 21:592 2-Methylcardols 9:315,318,324,325, 332,333,335-227,341-343 Methylcastasterone 19:477 synthesis of 19:477 (3R,7S)-de-O-Methy!centrolobin 17:366 (-)-De-O- Methyl-centrolobin 26:902 Methylcholanthrene-induced fibroscoma 25:432 (24R)-24-Methylcholest-4-en-3-one 25:419 (24R)-24-Methylcholest-5,7,22-trien-313ol (ergosterol) 9:447 24-Methylcholesta-5,22-dien-313-ol 9:471 24-Methylchole sta-5,24-diene-313-ol 20:234 24-Methylcholesterol 25:416,417 3-Methyl-cis, cis-muconate 8:299 cycloisomerisation of 8:305 3-Methyl-cis, cis-muconic acid 8:298, 299,308,302 3-Methyl-cis, trans-muconic acid 8:308 (+)-N-Methylconiine 13:479 A 9(I t)6c~-Methylcortexolone 9:425,428 (c~-Methylcrotyl) boronic ester 11:423, 424 from (S,S)- 1,2-dicyclohexyl-1,2ethanediol dichloromethyl boronate 11:423,424 preparation of 11:423,424 Methylcyanodithioformate 6:433,434 2-Methylcyclobutanone 6:314 synthesis of 6:314 1-Methylcycloheptatriene 13:32 1-Methylcyclohexanol 8:365,366 1-Methylcyclohexene 25:150 7-Methylcyclooctatetraene 21:306 Methylcyclopentanoid monoterpenes 20:43-48 biogenesis of 20:43-48 stereoselective synthesis of 20:41-76 synthesis of 20:48-76
S-Methylcysteine sulfoxide 23:458 N-Methylcytisine 21:51 (-)-N-Methylcytisine 26:487 N-Methyl-D-aspartate (NMDA) receptors 28:184 EGb as antagonist of 28:184 radioligand binding of 28:184 N-Methyl-D-aspartic acid 21:95;22:25 (Z)-9-Methyldec-4-enal 26:83 7-Methyldecalin 9:113 cis-9-Methyldecalin 9:272,280 trans-9-Methyldecalin 9:272,280 N-Methyldecarine (8-O-demethylchelerythrine) 14:783,784 from 7-O-demethyl oxychelerythrine 14:783,784 synthesis of 14:783,784 (+)-O-Methyldehydroancistrocladine 20:431 N-Methyldehydrobutyrin 9:496 24-Methyldemosterol 25:417 N-Methyldeoxynojirimycin 10:540 6-O-Methyl-D-glucose 15:435 3-O-Methyl-D-glucose 7:268,275,277 4-O-Methyl-D-glucuronic acid 7:181 Methyl-D-glycero-pentopyranoside 6:361 [3-Methyldigoxin 13:663;664 N-Methyldihydroarcyriarubin A 12:376 from N-methylarcyrinrubin A 12:376 Methyldilactone 8:312 3-Methyldodec- 1-en-3-ol 26:72 Methyldolichosterone 19:261 isolation of 19:261 Methyl-DOPA 6:334 from (3,4-dimethoxyphenyl) methyl methyl ketone 6:334 5'-Methyl-DOPA (dihydroxyphenylalanine) 10:106 N-Methyldopamine 21:57 3-O-Methyl-D-xylopyrasone derivatives 6:374,375 3-O-Methyl-D-xylose 7:275 N-Methyldysideathiazole 25:890 Methylecgonine 22:722,727 9-Methyleicos-4-enal 26:84 19-Methyleicos-4-en-l-ol 26:84 5-O-Methylembelin 7:83
525 c~-Methylenation 8:21,29;10:13,17,25; 13:33 Methylenation 8:26,29,30 with Lombardo reagent 11:40,41 Methylene 2,3'-biplumbagin 2:213, 215-217 biosynthesis of 2:229,230 c~-Methylene butyrolactone 27:856 24-Methylene cycloartenol 20:702 from Salvia nemorosa 20:702 24-Methylene cycloartenyl linolcate 9:461 Methylene cyclohexane 6:21,22 Piers annulation of 6:21,22 7,8-Methylene dioxyanthracene 11:120 2-Methylene glutarimides 14:747 isonitramine from 14:747 nitramine from 14:747 24,28-Methylene-24-propylchoesterol 9:36-38 from Pseudaxinyssa species 9:38 Methylene-3,3'-biplumbagin 5:754,755 Methyleneabscisic acid 27:347 Methyleneazulenones 14:332 1,1 '-Methylene-bis (3,7-diisopropylazulene) 14:340,341 oxidation of 14:340,341 1, l'-Methylene-bis (3-methylazulene) 14:335,336 3,3'-Methylene-bis (guaiazulene) 14:328 oxidation of 14:343-345 Methylene-bis-(dichlorophosphane) 9:527 (+)-2-Methyleneborane 4:650-652 acid catalysed rearrangement of 4:650,651 optical purity of 4:652 24-Methylenecholesterol 20:234,238 ( 22R,23R)-22,23-Methylenecholesterol 9:36,37 from Dysidea species 9:37 from Siphonoborgia species 9:37 from Xestospongia species 9:37 X-ray analysis of 9:37 (23R,24R)-23,24-Methylenecholesterol 9:36,40,41,43
from Colletotrichum nieaeensis 9:37 from Petrosiaficiformis 9:37 (28-14C)-24-M ethylenec ho lesterol 9:42,43 (24-14C)-24-Methylenecholesterol 9:44 24-Methylenecholestrol 25:417 24-Methylenecycloartan-3-one 9:288, 289 24-Methylenecycloartan-3 [3-ol 9:288, 289 24-Methylenecycloartenol (24-methylcycloart-24 (24')-en-3~-ol) 29:587 effects on CHY 29:587 Methylenecyclohexane annulation 6:54 in (+)-amijitrienol synthesis 6:53 in isoamijiol synthesis 6:54 c~-Methylenecyclopentanone moiety 15:176 2,3-Methylenedioxybenzoic acid 22:495 3,4-Methylenedioxycinnamic acid 5:479,480 2-(3,4-Methylenedioxyphenyl)quinoline 26:820,821 (Z)-Methyleneiminium ion 11:203 c~-Methyleneindolenines 9:190-194 y-Methylene-y-butenolide (protoanemonin) 10:149 c~-Methylene-y-butyrolactone 8:198 synthesis of 8:195,196 c~-Methylene-y-lactone (-)-3-epizaluzanin C 14:366 (-)-Methylenolactocin 16:699 antitutmor antibiotic 16:699 synthesis of 16:699 Methylenomycins 14:589,610 8'-Methylenoxides 27:348 (-)-N-Methylephedrine 13:118,119 O-Methylepoxyshikoccin 15:163 13C-NMR of 15:165 from Rabdosia shikokiana var. occidentalis 15:174 IH-NMR of 15:164 5'-O-Methylerbstatin 15:448 6-O-Methylerythromycin A 165,179 synthesis of 13:165 7-Methylesculin 26:317,333,334,342
526 7-O-Methylesculin 26:332-334,342 10-(R)-O-Methyleudistomidin C 25:817 N-Methylfindersine 7:191,192 O-Methylflavinanthine 3:426 synthesis of 3:426 (+)-3'- O-Methyl fukugetin 5:758 O-Methylfumarofine 1:201-205,211 3-O-Methylgalactose 15:431 3-O-Methylgancaonin P 28:229 biological activity of 28:229 4'-O-Methylglabridin 28:229 biological activity of 28:229 (+)-4'-O-Methylglabridin 4:391,392 synthesis of 4:391,392 3-O-Methyl-glucose 7:272 N-Methylglutamic acid 21:414 (S)-(+)-2-Methylglutarate 15:228 3-O-Methylglycerol 28:224 anti-microbial activity of 28:224 anti-Helicobacter pylori activity of 28:243 1-O-Methylglyfoline 13:363 6-O-Methylglyfoline 13:376 Methylgrandiflorenate 17-nor-ketone 19:395 O6-Methylguanine-DNA-methyl transferase 26:913 (+)-O-Methylhamatine 20:432 Nb-Methylharmalane 26:1060 2-Methylheptadecane 19:125 pheromone of 19:125 N-Methylhernangerine 30:565,594 as platelet aggregation inhibitor 30:594 (+)-N-Methylhemangerine 30:590 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:589 (4Z,9Z)-24-Methylhexacosa-5,9-dienoic acid 26:83,84 (R)-2-Methylhexanal 19:54 Methyl-histamine 15:328 Methylhomatropine 22:738 O-Methylhoslundin 2:133 7,6ot-Methylhydrocortisone 9:424 6ot-Methylhydrocortisone 9:427,428
10-Methyl-hydronaphthalen- 1-olmonosulfonate esters 14:356 Wagner-Meerwein rearrangement 14:135 12-Methylidene- 10Z, 13Z-nonadecadienoic acid 9:570 Methylidenenorbomene 8:150 3-Methylidolizidine-l,2-diols 12:351 from 2-cyano-6-oxazolopiperidine 12:351 1,1', 1"-Methylidynetri(3-methylazulene) 14:335 1-Methylimidazole 4:270 as catalyst 4:270 2-Methylindolo (2,3-(x) quinolizidine 14:720-722 synthesis of 14:720-722 1-Methylindolo [2,3-ot] quinolizine 1:147 synthesis of 1:207-209 Methyline iminium ylide 1:249 O-Methylipalbidine 1:284,285 synthesis of 1:284,285 2-Methylisoborneol 26:353,365-367 N-Methylisoindoline 8:402,403 3'-O-(Z)-Methyljasmonate 19:158, 19:161 4'-O-Methylkaempferol 25:541,544 Methylkanamycin 14:145 17-O-Methylkribine 9:179 O-Methyl-L-arabinose 7:297 (+)-5-O-Methyllicoricidine 4:388,389 synthesis of 4:388,389 TBDMSCI protection in 4:384, 389 4'-Methylluteolin 27:843 Methyllycaconitine 22:17;25:528; 26:871 O-Methylmacusine B 13:387 Methylmalonyl CoA 11:194,195 hypothetical incorporation of 11:195 with macrolide antibiotic 11:195 Methylmalonyl CoA 11:194,195 with macrolide antibiotic 11:195 (R)-Methylmalonyl CoA 11:195 (S)-Methylmalonyl CoA 11:195
527 (2S)-Methylmalonyl CoA 11:195,196 from propionyl CoA 11:195,196 (2R)-Methylmalonyl CoA 11:195-198 from succinyl CoA 11:195-198 N-Methylmaysenine 21:442-446 synthesis of 21:445,446 5-Methylmellein 9:288,289;15:383 from Euphorbiafidjiana 15:385 from Fusicoccum amygdali 15:385 from Hypoxylon and Numularia spp. 15:385 from Phomopsis oblonga 15:385 from Valsa ceratosperma 15:385 N-Methylmorpholine N-oxide (NMO) 8:23;14:270 3-Methylmuconate 8:298-300 synthesis of 8:300 2-cis,4-trans-3-Methylmuconic acid 8:302 4-Methylmuconolactone 8:298,299 (+)-3-Methylmuconolactone 8:300 from 2-nitro-4-methyl-phenol 8:300 (4S)-3-Methylmuconolactone 8:302 bromolactonisation of 8:301 (S)-(+)-4-Methylmuconolactone 8:302 3-Methylmuconolactone 8:306 absolute configuration of 8:301 cis- 10-Methylnaphthalenol monotosylates 14:363 trans- 10-Methylnaphthalenol monotosylates 14:363 2-Methylnaphthazarin 2:213,215,216; 5:754,755 4-(Methylnitrosamino)-l-(3-pyridyl)-lbutanone (NNK) 25:65 N-Methyl-nitrosourea(MNU) 25:65 N-Methyl-N'-nitro-N-nitroso-guanidine 5:599 N-Methyl-N-nitrosourea (NMU) 29:76 induced colon tumors 29:76 7-con-O-Methylnogarol 14:47,78,79 antitumor activity of 14:48 (+)-7-con-O-Methylnogarol 14:72-76 total synthesis of 14:72-76 (+)-7-con-O-Methylnogarol 14:83-90 synthesis of 14:83-90
3-O-Methylnordihydroguaiaretic acid 24:742 anti-HIV activity o f 24: 742 Methylnormacusine B 4:386 O(+)-N~-Methyl-N~-acetylphlegmarine 18:341 (+)-Methyl-O-acetyl-isoreserpate 25:18 (+)-Methyl-O-acetyl-isoreserpine 25:24 Methyloligobiosaminide 22:177 Methyl-O-p-tolylsulfonyl-a-D-glucopyranoside 8:337,338 4'-O-Methylosajin 4:382,385 from 5,7-dihydroxyisoflavome 4:382,385 Methylotrophic bacteria 1:170 N-Methylovigerine 30:590 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:589 3-Methyloxacylotridecan-2-one 26:69 (+)-O-Methylpallidinine 1:702 from Chamaecyparis pisifera 1:702 synthesis of 12:470,471 13-Methylpentadecanoic acid 26:64 antimicrobial activity of 26:64 4-Methylphenyl thiochloroformate 13:10 2-Methylphenyl-2,3,4,6-tetra- O-ace tylc~-D-galactopyranoside 21:164 et-Methyl-phenylacetic acid 10:412 alkylation of 10:412 by lithium isopropylamides 10:412 4-O-Methylpicropodophyllotoxin 26:193 Methylpiperbetol 26:243 as PAF-induced inhibitor 26:243 Methylpiperbetol 26:243,244 N-Methylpiperidine 21:56 O-Methylpisiferic acid 1:702-704 synthesis of 1:702-704 (-)-Methylpluviatolide 26:799 4-Methylprimaquine 22:150 trans-4-Methylproline 21:408 2-Methylpropane- 1,3-diol 13:84
528 5-(2-Methylpropyl) pyrrolidinone 13:131,132 13-Methylprotoberberine alkaloids 1:219-221 synthesis of 1:219-221 Methylpsedolycorine 26:615 (-)-N-Methylp seudoconhydrine 13:479 R-Methyl-p-tolyl sulfoxide 6:263 as chiral precursor 6:301,302 N-Methylputrescine 22:730 2-Methylpyridinium salts 6:429 reaction with alkynyl Grignard reagents 6:429 4-Methylpyrocatechol 8:299,309 N-Methylpyrrolidine 21:56 4-Methylquinol 16:618 reaction of 16:618 (Methyl-R) [methyl-ZH1, 3H] methionine 11:207,209,210 Methylrhodomelol 4:712,714,725 synthesis of 4:712,714 3-Methylrifamycin S 23:81 Methylrocaglate 26:203 7-0 Methylrosmanol (abietane diterpene) 29:575 effects on HIV- 1 protease 29:575 7-O-Methylrosmanol (abietane diterpene) synthesis 29:575 from carnosolic acid 29:575 1[3-Methyl-RS-533 12:145-148 synthesis of 12:147 gem-Methyls 27:333 (Methyl-S)-[methyl-ZH~,3H] methionine 11:207,209,210 (Methyl-S)-[methyl-2H~, 3H] reticuline 11:204 Methylsalicylic acid 11:198,1996biosynthesis of 11:198,199 by Penicillium patulum 11:198, 199 3-Methylsampangine 23:6 N-Methylschumannificine 21:140,141, 143,145 N-Methylschumanniophytine 21:152 Methylseleno acetal 8:6 reaction with n-butyllitium 8:6 reaction with 14-dibromopentane 8:6
2-Methylseleno-2-phenyl-6-heptene 8:12,13 from 1-methylseleno- 1-phenylethyllithium 8:7 from 5-bromo-l-pentene 8:7 synthesis of 8:7 transformation of 8:7,8 2-Methylseleno-2-phenyl-6-methyl-6heptene 8:7 N-Methylsempervirine 1:159 synthesis of 1:139 N-Methylserotonine 15:328 O-Methylseryl thiazole 25:885 O-Methylshikoccin 15:163-165,174 13C-NMR of 15:165 from Rabdosia shikokiana var. occidentalis 15:174 1H-NMR of 15:164 1[3-Methyl-SM-7338 12:145-148 synthesis of 12:147 30-Methylspergulagenate 7:144,145 [~-Methyl-styrenes 27:753 Methylsulfinyl indoles 25:861 (Methylsulfinyl) (methylthio) methane 11:351 (E)-5- Methyltetradec-4-enal 26:72 wittig reaction of 26:72 13-Methyltetrahydro protoberberine 14:790,791 (+)-ambinine from 14:790,791 (+)- 11-epiambinine from 14:790,791 synthesis of 14:790,791 2'-N-Methyl-tetrandinium chloride (bisbenzylisoquinoline) 29:578 effects on ACE 29:578 1-~-Methylthienamycin 4:432 antibiotic potency of 4:432 by azetidione synthesis 4:437, synthesis of 4:460,462,465, 469,470 3-S-[(Methylthio) carbonyl]-3-thiohexofuranose derivative 14:168 (Methylthio) methyl group 1:272,273 as carboxy protecting group 1:272,273 4-(M ethylthio)-(E, Z)-3-bute nyl glucosinolate 26:1085
529 4-(Methylthio)-(E, Z)-3-butenyl isothiocyanate (MTBI) 26:1073, 1075-1079,1082-1084,1090,1092, 1093,1098-1100,1102,1103,1105 3- [4-(Methylthio)-3-buenyl]-5-benzyl-2thiohydantion 26:1089 3- [4-(Methylthio)-3-butenyl]-5-[2(methyl-thio)-ethyl]-2-thiohydantoin 26:1089 3- [4-(Methylthio)-3-butenyl]-5-isobutyl2-thiohydantoin 26:1089 3-(Methylthio)methylene-2-thioxopyrrolidine (MMTP) 26:1073,1081-1084, 1092,1093,1095,1096,1099,1100, 1102,1103 (+)-2-Methylthio- 1,2,-trans-cyc lopropanedicarboxylic acid 25:845 3-Methylthio-2-oxopropanals 1:272,273 acetal derivatives of 1:272,273 acetal of 6:335,336 synthesis of 6:335,336 3-Methylthio-2-propenyl p-tolyl sulfone 6:309,340-343 Methylthioadenosine 17:15;25:829 Methylthiolation 6:329 N-(3-Methylthiopropyl) pyrrole 21:406 Methylthiotidine 25:813 5-Methylthiovaracin 25:834 Methyl-trans-cinnamate 23:808 O-Methyltransferases 25:505 (R)-I 7-Methyltricos-4-en-l-ol 26:87 Methyltrineracetal 30:707 structure of 30:707 N-Methyltryptamine 21:68,84 2-Methyltryptophan 11:209 from tryptophan 11:209 S (+)-N-Methyltryptophan 5:752 methyl ester of 5:752 16[3-Methyltubifolidine (curan) 1:38,39 13c~-Methyltylohirsutine 12:301 13ct-Methyltyohirsutidine 12:301 Methylumbeliferyl-phosphate 26:378 4-Methylumbelliferone 7:53;18:985 6-Methyluracil 4:226 1-Methyluric acid 22:6 3-Methyl-valerolactone 8:45,52 (+)-4R-Methyl-valerolactone 8:56
Methylvinyl ketone 6:427,428 in solenpsin A synthesis 6:427, 428 N1-Methylvoaphylline 5:126 O-Methylvulgarolide 18:20 4'- O-Methylwaranglone 4:382,385 from 5,7-dihydroxyisoflavone 4:382,385 1-Methylxanthine 22:5,6 3-Methylxanthine 22:6 7-Methylxanthine 22:6 Methylxanthine theophyline 25:532 Methylxanthines 22:20 2-O-Methylxylose 7:297,299 2-Methyl-),-butyrolactone 25:136,138 N-Methyl-c~-aminobutyric acid 9:496 Methyl-ct-D-arabinopyranoside 15:431 Methyl-~-D-glucopyranoside 15:431 Methyl-c~-D-pyranoside 14:180 Methyl-ct-D-ribopyranoside 15:431 Methyl-~-ethylacrylate 14:850 preparation of 14:850 Methyl-~-C-glycosides 10:345,346 Methyl-[3-D-xylopyranoside 15:431 Methymycin 11:151 synthesis of 11:151 Methynolide 11:151,152 synthesis of 11:158-163 3-[a-Methyoxy(~-methylthio)] methyl2-thioxopyrrolidine(raphantin) 26:1083 Methyoxy-2-phenylquinoline 26:820 2,3-Bis(Methyoxycarbonyl)-1-(3,4dimethoxy phenyl)-4-hydroxy-6,7,8trimethoxynaphthalene 26:196 3-Methyoxysampangine 23:6 4-Methyoxysampangine 23:6 Methysticin 22:529,540 6-Methyl-5-hepten-2-ol 25:143 O-Methylbufotenine 25:531 Methytene blue 25:349 Metmyoglobin/hydrogen peroxide 25:934 Metolachlor 25:669 Metridium illicifolia 18:665 Metridium loesner 18:757 Metridium senile 18:813 Metronidazole 22:625,626;25:617
530
Mevalonate 21:314 Mevalonate 5-diphosphate 11:219,220 isopentenyl diphosphate from 11:219,220 Mevalonate 5-diphosphate decarboxylase 11:219,220 monoterpene from 11:219,220 sesquiterpene from 11:219,220 Mevalonic acid 7:324,325,327,329331,340-343,346-349,351,352,357, 358,:360,361,363 ;11:200;13:553; 21:207,721 ;25:130 from acetyl CoA 7:322 from glucose 7:345 phosphorylation of 7:322 prenyl diphosphates from 7:322 (R)-Mevalonolactone 1:271 Mevalonolactone 13:621 Mevastatin 21:212 Mevinic acids 13:553-625 synthetic studies 13:553-625 (+)-Mevinolin 11:335,336 biological activity of 11:335, 336 3-hydroxy-3-methyl-glutarylcoenzyme A reductase inhibitor of 11:335,336 reductase inhibitor of 11:335, 336 total synthesis of 11:335-377 Mevinolin 13:553,561;22:245,252 biogenesis of 4:620 synthesis of 13:553,561 Mexicanin I 29:90 activity in NFkB assay system 29:90 Meyer et al. 29:191,394 carnosic acid synthesis by 29:191 steganes synthesis by 29:394 Mezerein 20:22;25:937 Mezerin-induced superoxide anion radical 25:938 MgBr2-catalyzed 11:451 cyclocondensation 11:451 MgO procedure 6:411 Mhakumo 23:655 Micaculin 15:36 from Richardella dulcifica 15:36
Micale cecilia 21:211
Mice 30:27 antitumor activity in 30:27 Micellar electrokinetic chromatography 21:543 Michael (1,4-addition) reaction 147-199 Michael acceptors 16:650;18:315,329, 334,339,369 c~,[3-unsaturated orthoesters 3:146 Michael addition 5:181,182;6:5-7,74, 75 ;8:224,277 ;9:343,347;10:61,164, 183,412;11:96,97,123 ;14:5,37,39, 42,118,274;15:272;16:30,155,424, 582,700; 18:10,63,81,333,343,355, 374,369,378;22:278,285;26:1237 2-amino alcohol by 12:411,413 asymmetric 14:510 base catalyzed 14:521 carbocycles 8:409-428 diastereoselective 11:286 enantiospecific 16:221,262,613 in the synthesis of 8:409-428 intramolecular 3:83;10:51; 11:312;12:17;14:521,523,524, 736;16:695 of alcohol 16:104 ofalkoxides 12:411,413 ofdiene 16:548,595 of enolates 10:407 of levoglucosenone 14:271,272 of methyl group 10:414,415 of MT-sulfone 6:337,347 of natural products 8:410-412 of nitroalkane dianion 1:311, 312 of trimethylsilyl ketene acetal 10:353 of c~-ethylidene-?-lactone 10:405,406 of ct-formyl-c~-phenyl acetic acid 10:408 ofc~-keto acetal 14:510 stereoselective 1:489,490 Stork modification of 10:185 tandem 4:556,557 to nitro olefins 10:407;12:411, 413
531
to [3-methylated enone 10:414, 415 with methyl vinyl ketone 14:510 Michael cyclization 16:437 intramolecular 14:552 Michael initiated ring closure 24:769, 770 for isopicropodophyllone analogues 24:769,770 retro-Michael reaction 26:110 Michael reaction 6:70,71;9:435,437, 516;11:31,38,39,41,42;13:29,30,180, 398,404-406,417,418,437,440,448, 458,609,618;16:494;24:7 aliphatic acceptors 4:705,706 alkenoylcyanide acceptors 4:709-711 asymmetric 14:551-567 chiral building block from 14:551-567 cyclic ene-dione acceptors 4:709 cyclic enone acceptors 4:707-709 intramolecular 14:551-567 reaction mechanism of 14:551-567 with quinone methides 4:712 with vitamic C 4:705-715 Michael type addition 18:65,269,302, 303,305,307,309 of nucleophilic glycosyl radical 11:464 [3-amino ketone 8:286 Michael-Aldol reaction 3:132-143 Michael-Arbuzov transformation 13:273 Michael-induced cyclization 14:755, 756 Michaelis-Arbuzov reaction 4:68 Michaelis-Menten model 7:29 Michael-Michael construction 12:203 Michael-type acceptors 12:99 Michael-type addition 8:286 Michael-type quinolizidine ring closure 29:427 reaction pathways of 29:431 role of piperidine in 29:427 stereochemical course of 29:488
stereochemistry of 29:427 Wittig-Horner reaction in 29:427 Michelenolide 27:565 Michellamine A 20:408,442,443-446 Michellamine B 20:443,446,451 from Ancistrocladus korupensis 20:442 Michellamine C 20:445,446 Michellamines A,B,C alkaloids 27:865 analogue glaucine 27:868 apomorphine 27:866,867 (+)-boldine 27:866 bulbocapnine 27:866 nitrogenated compounds 27:868 sanguinarine 27:866,867 Miconia myriantha 29:571 Miconidin 9:321,329;26:797,798 Microbacterium lacticum 26:1122 Microbes 1:677-708 for chiral synthesis 1:677-708 Microbial hydroxylation 9:416 Microbial oxidation 18:430-432 of arenes 18:430-432 Microbial reduction 4:493 ofketo acids 4:493 by Baker's yeast 6:13 of Kloeckera magna 6:13 Microbial secondary metabolites 15:439-463 screening of oncogene function inhibitor from 15:439-463 Microbial transformation 9:416;13:298; 23:34 carbaaldopyranoses synthesis by 29:469 oflimonene 16:208 of isophorone 26:307 of SAM 23:21,29,34,41 of xanthurenic acid 26:991 of 8-hydroxyquinaldic acid 26:991 Microbicidal compound 30:406 against sexually-transmitted disease agents 30:406 Microbiological evaluation 30:739 Microbiological reduction 13:556 ofracemic dione 13:556 Microbiostatic inhibitory activity 26:402
532 Microcionin-2 17:15 Micrococcus flavus 12:400 Micrococcus luteus 12:400;13:283; 15:389;21:275;23:252;24:713; 25:258,722,777,778;30:693,738 antifungal activities against 30:738 minimal inhibitory concentration (MIC) of 30:693 Micrococcus lysodeikticus 26:1122, 1124 Micrococcus sp. 21:259;25:48,79,94, 719;26:1155 Micrococcus varians 8:102 Microcolins 25:718 Microcosmus vulgaris 28:721 Microculture tetrazolium 21:259 Microculture tetrazolium (MTT) assay 21:262 Microcystins 9:496,498,499;18:269; 25:733 Microcystin-LR 20:896,905,907,909, 910 Microcystis aeruginosa 25:799;26:359, 365,366,367 Microcystis genera 27:879 Microcystis microcystins 25:543 Microcystis sp. 26:258,352,354 Microcystis viridis 26:366 Microdilution method 20:712 Microginin-A 25:799 Microginin-B 25:799 Micromelum compressum 22:526 for convulsions 22:526 Micromelum tephrocarpum 26:800 Micromeria fruticosa 27:377 Micromonospora echiospora 25:796 Micromonospora lacustris 23:55 Micromonospora sp. 23:57;25:841 Micromorphological studies 27:876 Micronucleus test 27:303 Microorganisms 30:738 chemical defense against 30:738 Microozonolysis 6:455 Microphyllinin acid 9:317,328 Microschlerodermin A 26:1215,1216 Microscleroderma sp. 26:1175,1215, 1217,1218 Microsclerodermin B 26:1215,1216
Microsclerodermins C-E 26:1216,1217 Microsomal oxidase 6:374 Microsomal oxidation 19:188 Microsomes 5:448,452 Microspectrofluorometry 26:469 Microspinsodamide 28:680 in HIV-1 infection 28:681 Microsporum canis 12:400;21:602; 26:227,228 Microsporum guinckeanum 5:294 Microsporum gypseum 12:400;21:602, 758;26:228 Microsporum sp. 26:1127 Microstegiol 20:680 from Salvia candidissima 20:680 Microtubule stabilizing agents 30:5 discodermolide as 30:5 epothilone as 30:5 eleutherobin as 30:5 laulimalide as 30:5 taxol as 30:5 Microtubule-depolymerization 25:473 Microtus montanus 27:213 Microwave oven extraction 21:577 Microxina sp. 28:691 Microxine 28:691 as Cdc2 kinase inhibitor 28:691 effects on solid tumours 28:145 Midecanolide 11:160 Midecanolide A1 11:163,170 Midland's pinyl borane 11:424 Miglyol 7:113 Migraine 30:194,206,367,368 role of serotonin (5-HT) 30:367, 368 use of Tanacetum parthenium in 30:206 treatment of 30:206 use of A6-tetrahydrocannabinol (THE) 30:194 Miharamycins 11:434,19:129 Mikania cordifolia 22:353 Mikania guaco 29:89 Mikania obtusata 26:810 Milbemycins 12:4-9;14:519;26:425, 426,432,453 and 13series of 12:4-9 structure of 1:435-495
533 synthetic approaches to 1:435-495 Milbemycin 13~ 12:22 synthesis of 12:22 Milbemycin [33 1:451-454;12:26 homochiral synthesis of 1:451-454 synthetic routes to 1:448-462 synthesis of 12:26 Milbemycin D 1:469 synthesis of 1:469 Milbemycin D-K 12:6 Milbemycin E 16:659 from Streptomyces sp. 16:659 (-)-Milbemycin I 16:661 Milbemycin ot~-Otl0 12:4-9 Milbemycin [31-[33 12:4-9 Mildiomycin 4:241, activity of 4:245 structure of 4:246 Milimorin 5:678 Milius banacea 20:483 exoaporphines of 20:483 Milkevetches 27:444 Miller-9E-enolide 29:89 activity in NFkB assay system 29:89 Milleria cordifolia 29:89 Milleria guaco 29:89 Milleria quiqueflora 29:89 Milletia pachycarpa 29:771 Millingtonia hortensis 5:14 Millipore filters PSAC 02510 22:375 Miltirone 29:212 as tricyclic diterpenoid quinine 29:212 antioxidant behavior of 29:212 biological activity of 29:212 isolation of 29:212 Miltirone synthesis 29:212 by Banjerjee et al. 29:215 by Knapp and Sharma 29:214 by Majetich et al. 29:215 by Nasipuri and Mitra 29:212 by Snyder et al. 29:214 Mimengoside A 21:674 Miharamycins 1:398 synthesis of 1:404-410
Mimosa hostilis 25:248 Mimosa pudica 26:481 Mimosa tenuiflora 24:151,152 Mimosamycin 21:265,266;25:825 Mimosine 22:29 Mimososideae 25:92 Mimulaxanthin 6:136,137,143,144 Mimulus sp. 6:137 mimulaxanthin in 6:137 Mimusopane 23:495 Mimusops elengi 23:487 Minabeolide-3 19:470 isolation of 19:470 from Minabea species 19:470 Minalemines D-F 25:897,898 Mineralcorticoid aldosterone 25:516 Miniatoside A and B 15:61 from Patiria miniata 15:61 Minimal inhibitory concentration (MIC) 30:693 of Bacillus subtilis 30:693 of Bacillus pumilus 30:693 ofMicrococcus luteus 30:693 of Staphyllococcus aureus 30:693 of Staphyllococcus epidermidis 30:693 of Staphyllococcus saprophyticus 30:693 of Staphyllococcus warnieri 30:693 Minimization method 17:500 BDNR 17:500 Minovine 19:92 synthesis of 14:635,636 Minoyobates bombetes 19:81 Miosin light-chain kinase 27:858 Miotic agent 21:750 Mioxinjection 27:322 ofabscisic acid 27:322 Mirabilisjalapa 23:342 Misakinolide 5:396 Misakinolide A 5:355,358,396,397; 26:1197,1198 Miserotoxin 27:526 Misoprostot 25:616 Mitaria coccinea 25:251 Mitariosides A-D 25:251
534
Mithramycin 3:173;24:547;26:220 antiviral microbial-derived compound 24:547 Miticidal properties 28:390,414 of Azadirachta indica 28:414 of estragole 28:414 of eugenol 28:414 of linalyl acetate 28:414 of menthol 28:390 of terpenes 28:414 Mitochondrial monoamine oxidase 26:1260 Mitochondrial yeast cytochrome A peroxidase 27:736 Mitogen-activated protein kinase (MAPK) 25:522,547;26:753,951 Mitogenesis 30:4 induction by concanavalin A 30:4 Mitogenic effect study 27:798 Mitogenicity 28:530 of lipid A 28:530 to B lymphocytes 28:530 Mitogen-induced arctigenin 26:217 inhibitory activity of 26:217 Mitogen-induced mouse splenocyte proliferation 25:271 Mitomycin 1:340;4:573;5:439,440; 16:573 as anticancer drug 28:559 Danishefsky synthesis of 13:433 from D-glucosamine 13:434 from isomitocins 13:445-467 Kishi synthesis of 13:436-442 synthesis of 13:433-471 Mitomycin A 13:434,435,445-447,460, 467 from Streptomyces caespitosus 13:433 synthesis of 13:439-442 X-ray crystal analysis 13:434 Mitomycin B 13:439 from Streptomyces caespitosus 13:433 synthesis of 13:439-442 X-ray crystal analysis 13:434 Mitomycin C 13:435,460,467;21:137, 264 ;25:268;30:691
against hepatoma (HEPA-2B) 30:691 from Streptomyces caespitosus 13:433 synthesis of 13:440 X-ray crystal analysis 13:434 Mitomycin M 13:433 Mitomycin-based prodrug 21:160 Mitomycin-resistant tumors 21:264 Mitosane 13:434,436,437,443,444 synthesis of 1:340 Mitotic activity 2:380;21:751 of the cells 2:380 Mitoxanthrone 1:514 Mitragynine 21:72,79;22:24 Mitraphylline 14:751;25:25,26 Mitsonobu epimerization 24:63,64 Mitsonubu activation 3:328 Mitsonubu alkylation 3:313 Mitsunobu condensation 18:88 Mitsunobu conditions 16:461 Mitsunobu coupling 12:448 of 3,4-dimethoxyphenethyl alcohol 12:448 of 1-methyloxazolidien-2,4-dione 12:453 Mitsunobu displacement reaction 12:281 Mitsunobu inversion 1:695,697,698; 4:449,459;6:553,554 ;13:499,502; 18:7,237,246,259,281,470,893,903 Mitsunobu procedure 1:456;14:182 ring closure by 11:10 Mitsunobu reaction 1:205;4:86,456,457, 478,515,519;6:294,295 ;10:603; 11:404 ;12:305,312,319,468; 13:201, 443,485;14:15,275;16:79,350; 18:174,217,235,471 ;22:283; 24:36-37;26:1236;30:20,38 with phthalimide 11:236 Mixed function oxidases 7:8 Mixed inhibitors 7:40 Miyabenol A-C 26:552,556,558,560, 561 cis-Miyabenol C 26:556,560 possessing o-quinone 26:164 possessing spiroketal 26:164 MLCK 25:546
535
MMP2-CONFLEX 11:3 method 11:157,162,168 MMTP 26:1091,1092,1099 antimicrobial activity of 26:1091,1092,1099 Myrcene 3:107 MNDO calculation 13:164,165 Mniopetal E synthesis 29:131,133 approaches for 29:133 decomposition in 29:139 IMDA reaction of 29:1,3,9decatriene derivative in 29:131 via intramolecular Diels-Alder reaction 29:139 NOE experiments of IMDA adducts in 29:140 plausible transition states of 29:141 recovery of substrate in 29:139 use of Wittig reaction in 29:131 Mniopetals 29:128 mniopetal A,B,C,D,E,F 29:128 total synthesis of 29:148 MNU inuduced mammary tumors 25:46 MO4 27:771 tautomerization of 27:771 Moderate depression 30:603 treatment of 30:603 Modhephene 1:632,637;3:6,8,11,16,24, 61 ;13:37-39;14:490 epi-Modhephene 3:6,11,62 Modified Eschenmoser method 3:482 Modified Eschweiler-Clarke conditions 6:476 Modified Schollkopf's procedure 15:443 Moenjodaramine 2:175,176,205 '3C-NMR spectrum of 2:176 structure of 2:175,2:176 Moffatt oxidation 12:325,335;14:814, 815 Moghania strobilifera L. 22:526 for epilepsy 22:526 Mogroside IV 27:14,26,27 structure of 27:27 Mogroside V 15:22 Mogroside V(2) 27:6,7 structure of 27:7 (+)-Mokko lactone 14:368
Mokkolactone 29:89 activity in EBV assay system 29:89 Molamola 25:872 Molar decadic absorption coefficient 2:156 Molar ellipticity 2:160;15:424 Molar rotation 2:159 Molecular complexity C 3:29 Molecular dynamics (MD) 10:269 Molecular dynamics simulation 20:907-910 of microcystins 20:907-910 of nodularins 20:907-910 Molecular formula 30:570,581-584,586, 587 of (-)-hernone 30:587 of (+)-N-formylovigerine 30:582 of (7R,SS,7'R,8'R)-(+)-7'-acetyl5 '-methoxypicropodophyllin 30:586 of 7-formyldehydroovigerine 30:581 of demethylsonodione 30:570 of ernamymphine 30:582 ofherveline A 30:583 of ovihernangerine 30:584 Molecular interactions 5:575-581 of oligo (pyrrolecarboxamido) amidine antibiotics 5:575-581 Molecular mechanics 10:17,22,36 Molecular mechanics calculations 3:351 ;5:579;9:3,281-283;11:31,33 of [5.5.5.7] fenestrenes 3:118, 119 Molecular mechanics simulation 3:339-351,363 Molecular modeling (MOMO) 10:269; 15:213,344 ;24:326 Molecular rearrangements 5:792-794 of perezone 5:792-794 of sesquiterpenes 5:794-800 of grandiflurenic acid 19:389-410 Molecular recognition 18:819 by DNA 19:345 Molecular rotation 26:8 Klyne's rule of 26:8
536
Molecular target 21:84,96,98,99,107, 110 of alkaloids 21:5 Molinema dessetae 26:441 Mollamide 25:883 Mollic acid 25:182 Mollic acid arabinoside 25:182 Mollic acid derivatives 25:183 Mollic acid glucoside 25:182 Mollic acid xyloside 25:182 Mollugin 26:666 Molluscicidal activity 21:591,596,660; 22:614;24:799;28:59;30:153,332,333 as biological activity 24:799 of bergapten 23:357 ofLicania carii 28:60 of Licania densiflora 28:60 of Licania heteromorpha var. heteromorpha 28:60 ofLicania licaniaeflora 28:60 ofLicania pittieri 28:60 of Licania pyrifolia 28:60 of lapachol 30:333 of natural naphthoquinones 30:332 Molluscicide 7:425-427 Molluscs 22:3;28:647 outer body of 28:647 Mollusks 17:3;21:317 Moloney sarcoma virus 5:565 MOLT-4 cells 21:636 Molt-4 D-glucocerrbrosidase 19:352 Moltilin 13:156,158 Molybdate complexes 15:436,437 from di-and trisaccharides 15:436,437 Molybdenum-catalyzed elimination 21:380 Molybdenum (VI) oxidiperoxo compled for asymmetric epoxidation 4:344, 345 with (S) piperidine lactamide ligands 4:344,345 Momordica charantia 29:608,615 Momordica cochinchinensis 29:616 Momordica repens 29:616 Monacolin K 13:553 Monarch butterfly 21:107 Monascus ruber 19:168;22:251
Monascus spp. 22:251 Monatin 27:18,38 structure of 27:38 Monatin [4-hydroxy-4-(indol-3ylmethyl) glutamic acid 15:35 Monellin 15:36 Monensin 3:58;10:424 Monensin A 11:196,197 Moneses uniflora 25:777 Mongholicoside I 25:202 Mongholicoside V 25:202 Monilia spp. 2:323 Moniliformin 6:219,220;9:203,204, 214,215 Monilinia fructicola 23:142 Monilinia fructigena 5:278 Monmorium pharaonis 21:277 Mono and di-oleolglycerol 25:333 (Mono)-piperidine-[3-carbolines 14:758, 759 Mono-6-O-p-tolylsulfonylcyclomaltoheptaose 8:340 Mono-6-S-c~-D-glucopyranosyl-6thiocyclomalto-heptaose 8:340 Mono-6-S-D-D-glucopyranosyl-6thiocyclomalto-heptaose 8:340 C37-Monoacetylenic apo-carotenoids 6:149 C37-Monoacety' nic nor-carotenoids 6:149 C40-Monoacetylenic carotenoids 6:149 Monoacetylenic-7,8-didehydroastaxanthin 6:153 stereomutation sutdies of 6:153 2'-or 3'-Monoacylated ribonucleoside 14:285 2',3-acyl migration in 14:285 Monoalide 25:696 c~-Mono-alkoxylated piperazinediones 12:84 cyclization of 12:84 synthesis 12:83 Monoalkylation 6:341 of MT-sulfone 6:330,331,339, Monoalkylmalonic acid 13:74 condensation of 13:74 Monoalkyl-substituted polysulfides 25:843
537
Monoallenic carotenoids 6:135,136 Monoamine neurotransmitters 30:627 adhyperforin inhibitor of 30:627 in behavioral models 30:627 Monoamine oxidase (MAO) 5:411; 21:5,17,50;30:377,384 effect on dopamine 30:377 effect on noradrenaline 30:377 effect on serotonin 30:377 neurotransmitters degradation by 30:377 Monoamine oxidase activity 25:594 Monoamine-synthesis inhibitor 30:204 inhibition of antinociception by 30:204 Monobromination 11:253,254;12:83 of N,N-dialkyl glycine anhydrides 12:83 C(3)-Monobromination 4:656,657 of 8,9,10-trinoreamphor 4:656, 657 Monocaffeoylquinic acid 25:939 Monocalyptus subgenus 24:233 Monochlorinated sulfoxide 6:310 ot-alkoxysulfoxide from 6:310 chemcial reactions of 6:310 epoxysulfoxide from 6:310 from N-chlorosuccinimide 6:310 from sulfoxides 6:310
9-Mono-cis-tetradehydrocarotenoids
6:5 Monoclonal antibodies 21:159 Monoclonal antibody (MAO) 464,955 Monoclonal antibody immunoassay CIEIA 24:933,939,941,942 Monoclonal anti-I 10:484 biosynthesis of 10:484 I-antigenic determinant of 10:480,481 inhibition of 10:482 Monocrotalic acid 1:262;22:13 synthesis of 1:262 Monocrotaline 8:223;22:13 macrocyclic dilactone from 8:222 Monocyclic ketones 10:311-313 to bicyclic enones 10:311-313 Monocyclic sesquiterpenes 5:803-805
Monocyclic [3-1actams 12:118 from Nocardia uniformis 12:118 synthesis of 12:120,121 Monocyte chemoattractant protein I 25:598 Monodesethylamadiaquine 25:344 Monodesethylchloroquine 22:148 25:344 Monodesmosides 15:188 Monodesmosidic dammarane oligoglycosides 24:144 Monodesmosidic saikosaponins a,c,d, 24:146,148 Monodesmosidic saponins 21:80,675; 24:132-134,144 ;27:664 Monodesmosyl saponin 25:108 Monodeuterated tripeptides 11:212,213 monodeuterated penan from 11:212,213 Monodora tenuifolia 2:446 2-dimethylallylindole from 2:446 Mono-electronic perox~idase-catalyzed 27:770 Monofluoro alkane 27:334 Monofluoroestradiol derivatives 5:453 Monogagaine 5:125 Monoglycosides 7:268,272,273 Monogynol A 20:704 from Salvia montbretii 20:704 Monohba quadridens 5:225,231,253 Monohexosylceramide 18:799,814 from Sporothrix sohenckii 18:807 from Fusicoccum amygdali 18:807 from Fusarium lini 18:807 from Fusarium solani 18:807 from Aspergillus oryzae 18:807 from Aspergillus fitmigatus 18:807 from Aspergillus versicolor 18:807 Monohydric alkylphenolic acids (anacardic acid-type) 30:115-116 occurrence of 30:115 structures of 30:115-116
538
Monohydric phenolic lipids 30:113-114 occurrence of 30:113-114 structures of 30:113 7-Monohydroxyethyl rutoside 22:320 Monolignols 5:463 trans (E)-Monolignols 5:472 MONO-MAC cells 21:270 Monomethoxychrommene 2:125 Monomethoxytritylation 4:286 Monomethoxytrityloxyethylamino 4:289 as protecting group 4:289 N(G)-Monomethyl-L-arginine 26:951 Monomirium foricola 6:436 pyrrolidine venom alkaloids in 6:436 Monomorine 10:186 13C-NMR of 14:575 ~H-NMR of 14:575 as 3-butyl-5-niethyloctahydroindolizidine 6:445,447 asymmetric synthesis of 6:449,450 from 1,2-oxazine 6:449 from 2,6-1utidine 6:445,447 from Monomorium pharaonis (pharoh ants) 14:575 from pyrrolidine synthesis 14:575 MS of 14:575 synthesis of 6:445,447-449; 14:575,476 (+)-Monomorine 16:488,490 synthesis of 16:488,490 3-epi-Monomorine I 1:391 (+)-Monomorine I 11:241,242 from (S)-alanine 11:241,242 from Monomorium pharaonis 11:231 from (S)-pyroglutamic acid 11:241,242 synthesis of 11:231-244 Monomorine I 4:606;14:575,576 synthesis of 1:290,291,293, 389-391 (+)-Monomorine I 6:449,450 absolute configuration of 6:449, 450 from diethyl-L-tartarate 6:449,
450 synthesis of 6:449,450 (-)-Monomorine I 6:449,450 synthesis of 6:449,450 Monomonum carbonarium 6:436 pyrrolidine venom alkaloids m 6:436 Monomorium cyaneum 6:436 pyrrolidine venom alkaloids in 6:436 Monomortum ebeninum 6:436 pyrrolidine venom alkaloids in 6:436 Monomorium emersoni 6:436 pyrrolidine venom alkaloids in 6:436 Monomortum latinode 16:441 pyrrolidine venom alkaloids m 6:436 Monomor~um metoecus 6:436 pyrrolidine venom alkaloids in 6:436 Monomorium minutum 6:436 pyrrolidine venom alkaloids in 6:436 Monomorium pharaonis L. 1:389; 6:336,445,454;14:575 indolizidine alkaloids in 6:445 pyrrolidine venom alkaloids in 6:436 (+)-monomorine I from 11:231 Monomorium sp. 6:443 2,5-dialkylpyrrolines in 6:434, 443 trans-2,5-dialkylpyrrolidines in 6:434 pyrrolidine venom alkaloids in 6:436 Monomorium subopacum 6:436 Monomorium viridum 6:3436 Monomycin 26:831 Mononuclear cells (MNCS) 25:462,477 Mononuclear leukocytes 30:370 activity of tryptophan hydroxylase (TPH) in 30:370 2-Monooleoylglycerol 30:104 Monooxygenase 17:491 Mono-p-bromobenzamide 25:847 Monophosphate dehydrogenase 25:836
539
2'-or 3'-Monophosphorylated ribonucleosides 14:286 phosphoryl migration in 14:286 Monoprenylated flavanones 29:780 dorspoinsettifolin as 29:780 6-methoxyisolonchocarpin as 29:780 Monoprenylated flavones 29:787 as ephedroidin 29:788 3,3-dimethylallyl,2-hydro xy- 3methyl-3-butenyl as 29:787 dimethyldihydropyran as 29:787 licoflavone C as 29:787 6-prenyl apigenin as 29:787 8-prenyl-5-hydroxyflavone from 29:787 Monoprenylated monochalcones 29:770 bartericins as 29:773 hydroxydimethyldihydropyrano derivative of 29:771 4-hydroxylonchocarpin as 29:771 isobavachalcone as 29:771 NMR spectra of 29:771 of bis-dihydropyan derivative 29:772 paratocarpin D as 29:773 sophoradin 29:774 4,2',4'-trihydroxychalcone as 29:770 Monosaccharide-molybdate complexes 15:437 Monosaccharides 7:18,29,31,62; 13:207-212;30:279,447,451 as chiral synthons 4:625 ~3C-NMR spectra of 30:279 C(3 )-monosubstitution reactions 4:653 in hemiacetal form 30:451 stereoselectivity of 4:653 synthesis of 4:625 Monosaccharides with C1-P bond 6:352-356 Monosaccharides with C2-P bond 6:357-359 Monosaccharides with C3-P bond 6:357,360 Monosaccharides with C4-Pbond 6:360-365
Monosaccharides with Cs-P bond 6:365-375 Monosaccharides with C6-P bond 6:375-377 Monosaccharides with CT-P bond 6:377 Monosodium glutamate 7:457 Mono-substituted azulenes 14:335,336 oxidation of 14:335,336 Monoterpene 5:343;6:110;7:95,98,106109,112,114-118,120,124,126,427; 8:220;9:529 alcohols 17:79 synthesis 17:603 chiral 16:123,124 chiral pool 16:123 Monoterpene alkaloids 7:443,444; 9:163-199 from Strychnos dinklagei 6:522-530 from Valeriana officinalis 6:524 Monoterpene synthetase 7:123 Monoterpenic hydrocarbons 27:370 Monoterpenoid alkaloids 21:128 Monoterpenoid enantiomers 27:377 biological activity of 27:377 Monoterpenoid indole alkaloids 27:780 Monoterpenoids 4:625;16:123,124; 27:361;29:81 8-acetylharpagide as 29:84 costunolide as 29:97 isomerism of 27:361 limonene as 29:81 parthenolide as 29:92 perillyl alcohol as 29:82 structures of 29:85,93 zerumbone as 29:97 M ono-terulo yl-tri-p-carmaro yl-este rs 27:837 Monotes engleri 23:552,555 Monotetrahydrofuranic derivatives 28:437 as complex I inhibitor 28:436, 437 Monotoideae 23:531,552,554 structures of constituents of 23:554 Monotropein 7:440;26:666 Monovalent peptide 18:914-918 Monooxygenase 27:322
540
Montanin A 23:594 Montanin B 23:594 Montanin H 23:617 ~H-NMR data of 23:617 Montanine 20:325,353 Montanoa frutescens 24:806-811 phytochemicals from 24:806-811 Montanoa spp. 24:804-814 Montanoa tomentosa 24:799,804-817 phytochemicals from 24:807-811 Montanone 7:235 Montbretyl- 12-methyl ether 20:661 from Salvia candidissima 20:661 Monterine 21:79 Montezuma speciosissima 29:586 Monti 29:458 carbafuranose synthesis by 29:458 (9R)-(+)-Mophinandienone 16:505 Moraceae 22:723 Moracein B 28:230 biological activity of 28:230 Moracenin Aand B 4:618 from Morus alba Linne 4:618 relation to albanins F and G 4:619 Moracenins 25:594 Moraceous plants 17:451 ;28:226 anti-HIV flavonoids from 28:226 Morachalcone A 28:201 from moraceous plants 28:201 Moracin 30:222 as diarylethanoid derivatives 30:222 structure of 30:222 Moracin C 28:226,230 anti-human immunodeficiency virus (HIV) activity of 28:226 biological activity of 28:230 Moracin N 28:18 as aromatase inhibitor 28:18 Moradial 20:705 from Salvia pomifera 20:705 Moraprenyl (2,3,4,6-tetra-O-acetyl-[3-Dglucopyranosyl) phosphate 8:107 Moraprenyl (~-D-glucopyranosyl) phosphate 8:108
Moraprenyl diphosphate 2-acetamido-2deoxy-ot-D-glucose 8:91 Moraprenyl diphosphate monosaccharides 8:90,91 Moraprenyl diphosphate et-D-galactose 8:89 Moraprenyl monophosphate sugars 8:86 synthesis of 8:86 Moraprenyl phosphate 8:105,106 Moraprenyl trichloroacetimidate 8:107 P l-Moraprenyl, P2-(ot-D-glucopyranosyl)uronic acid diphosphate 8:108 Morbidity 30:747 in infants 30:747 Morbus Alzheimer 21:19 Morbus Parkinson 21:19 Morelensin 26:193,215,216 Morellofiavone 5:758 Moretenane 25:54 Morgula manhattensis 23:243 Mori and Mori 29:182 pisiferic acid synthesis by 29:182 Mori synthesis 13:500 of azitidinone derivative 13:500 Mori-Matsui synthesis 14:667-670 to taxodione 14:667-670 Morin 5:678;25:541,544;29:573,585 effects on ACE 29:580 effects on HIV- 1 protease 29:573 effects on LELA 29:585 effects on MMP 29:582 structure of 5:677,683 Morinaga oleifera for 22:526 Morinda lucida 7:427;26:673,805 Moringa concunensis 22:526 Moring, a oleifera 22:526 for epilepsy and hysteria 22:526 for nocturnal epilepsy 22:526 Moritoside 15:294 Morning sickness 30:561,597 treatment of 30:597 use of Hernandia moerenhoutiana in 30:561,597 use of Hernandia nymphaeifolia in 30:561,597
541 use of Hernandia voyronii in 30:561,597 Moronic acid 20:705 from Salvia pomifera 20:705 Morphiceptin 22:295 Morphinan 18:76 Morphinan isoquinoline alkaloids morphine 25:533 3-methylmorphine ecodeine 25:533 fl-codeine neopine 25:533 Morphinandienone 3:425 synthesis of 3:425 Morphinane alkaloid 24:294 Morphine 12:456,457; 18:43-109;21:20, 72,488;22:5 ;26:820;30:193,195,200, 801 as natural analgesic 30:195 as psychodelic drug 26:820 biosynthesis of 18:51-55 from Papaver somniferum 13:631 history of 18:45-55 inhibitory effects of 30:801 semi synthesis 17:633,636 synthesis of 18:56-98 Morphine alkaloids 20:292 Morphine-3-glucuronide 22:24 Morphogenic properties 30:367 ofserotonin (5-HT) 30:367 Morpholidate method 14:295 Morpholine 6:456 Morroniside 7:442 from Lonicera morrowii A. Gray 16:307 Mortania palmeri 5:678 Mortierella alpina 26:259 Mortierella ramannianus 19:578 Mortonia greggi 18:751 Mortonin A 23:665 Mortonin B 23:665 Mortonins A,B,C and D 18:751 Mortonol 18:751 from Mortonia greggi 18:751 Morus alba Linne 17:47,451,465; 29:573,585 ;28:200,208;29:580;582 cell cultures 17:471 hypotensive action of 28:200, 209
moracenin A and B from 4:618, 619 polyprenols from 8:36 Morus alba spp. 29:573 Morus bombycis 22:117;28:200 Morus cathayana 28:202,234 Morus flavonoids 28:215 effects on arachidonate metabolism 28:215 Morus lhou 28:200 Morus mongolica 29:705 Morus nigra 30:207 use as anti-inflammatory agent 30:207 use in folk medicine 30:207 Morus species 28:207 anti-hyperglycemic effect of 24:917 bombesin receptor antagonist from 28:221 hypotensive action of 28:207 inhibition of histamine release 24:914-917 Morus uralensis 28:234 Morusin 28:211 ;30:207 anti-human immunodeficiency virus (HIV) activity of 28:226 antinocicieptive effect of 30:207 anti-tumor activity of 28:211 biological activity of 28:212,230 Morusin hydroperoxide 28:210 from moraceous plants 28:210 Morusinol 28:230 biological activity of 28:230 Moschus moschiferus 8:219;24:906 muscone from 8:219 Mosher ester 11:361;12:478 absolute configuration of 13:77 Mosher's (+)-MIPA ester 1:370,371 Mosher's method 15:76;17:264,271,276 Mosquitocidal 24:864 bioassay of 24:864 Mosquitocidal activity 24:860 Mossambine 1:35 M6ssbauer spectroscopy 25:340,357 Motherwell 29:399 steganes synthesis by 29:399 Motuporin 26:1189,1217-1220, 1222-1227;27:880
542 from sponge Mouse Tail-flick assay 30:815 in vivo 30:815 Mouse mammary organ culture assay 30:593 activity of cancer hemopreventive agent 30:593 Mouse mammary organ culture model 30:591 chemopreventive activity in 30:591 Mouse skin carcinogenesis test 30:593 activity of cancer chemopreventive agent 30:593 Mouse vas deferens (MVD) 30:810 activity in receptor binding assay 30:810 Mozamides A 26:1184 Mozamides B 26:1184 MRSA 21:602,603,604 mrTNF-a-induced hepatic apoptosis 25:468 MSR inhibition 23:180 of sesquiterpenes 23:180 MTBI 26:1091,1092 antimicrobial activity of 26:1091,1092 MT-sulfone 6:329 acidity of 6:329 alkylation of 6:334 dialkylation of 6:332 from DMSO 6:329,330 Michael addition of 6:337-339 monoalkylation of 6:330,331, 339 organic synthesis with 6:329,330 properties of 6:329 synthesis of 6:329,330 MTT assay 21:149 MTT method 25:266 Mu receptors 22:24 Mucocutaneous leishmaniasis 30:742 by Leishmania braziliensis 30:742 Muconate pathways 8:295-313 stereochemical study 8:296 cis, cis-Muconic acid 8:295 syn addition of 8:296
Muconic acid pathways 8:295-313 cyclization of 8:298 Muconolactone 8:295,296 (4S)-Muconolactone 8:308,312 Muconolactone isomerase 8:298 Mucoproteins 26:1019 Mucor circinelloides 25:166 Mucor miehei 13:303;25:259 Mucor mucedo 21:607,608,611;30:739 antibacterial activity against 30:739 antifungal activity against 30:739 Mucor plumbens 25:253 Mucor racemosus 22:627 Mucor ramannianus 23:23,42,45 Mucor rhizopus 9:203 Mucor rouxianus 21:396 Mucor rouxii 5:276 Mucor sp. 2:323;25:723 Mucorales 9:203 Mucositis 21:158 Mucrine 27:565 Mucronulatol 366 27:498 Mucuna aterrima 26:435 Mucuna hassjoo 26:932 Mucunu sempervirens 25:93 Mueller Li-bronze reduction 10:408 of (+)-carvone 10:408 Mugil cephalus 18:486 Mugil umbelata 18:665 Mukaiyama ADD reagent 10:23,24 Mukaiyama aldol process 19:203 Mukaiyama aldol reaction 18:292; 30:17,42,43 Mukaiyama condensation 10:187 intramolecular 10:181,182,218 Mukaiyama conditions 12:244 Mukaiyama-Michael aldol condensation 16:664 Mukaiyama's protocol 11:289,296,297 Mukaiyama-type aldol reaction 26:1235,1237 Mukulol 10:25-29 synthesis of 8:178 Mukurozioside 1lb 27:13,21 structure of 27:22 Mulberrin 28:230 biological activity of 28:230
543
Mulberrochromene 28:230 biological activity of 28:230 Mulberrofuran B 28:230 biological activity of 28:230 Mulberrofuran C 28:209,210 hypotensive action of 28:209 from moraceous plants 28:210 Mulberrofuran F 28:209,210 hypotensive action of 28:209 from moraceous plants 28:210 Mulberrofuran G 28:209,210,212,230 biological activity of 28:212,230 from moraceous plants 28:210 hypotensive action of 28:209 Mulberrofurans 17:459 Mulberry tree 17:519;28:225 anti-human immunodeficiency virus (HIV) activity of 28:226 Mulberry, Diels-Alder type adducts 17:451 Muldamine 23:575,585 Mulheirn 19:552 isolation of 19:552 Multicaulin 20:673 Multidrug resistance 21:158 Multi-drug resistant cancers 30:5 chemotherapeutic agent for 30:5 clinical development for 30:5 Multidrug-resistant human cancer cell 12:390 staurosporine activity against 12:390 Multifidene 21:305 Multiflor-8-ene 25:59 Multiflor-9-ene 25:59 Multiflorane 25:53,59 (-)-Multiflorine N-oxide 15:524 from Lupinus hirsutus 15:524 Multifunctional calmodulin-dependent kinases 27:822,825,827 Multinucleate syncytia 30:397 Multiple antigen 18:920 Multiple hydrogen bonding 17:564 Multiple pathway modeling 23:18 Multiple quantum spectra 9:143,144 Multiple targets 21:89 Multipoint attachment model 27:11 Multireference Moller-Plesset theory 30:542
application of 30:542 Multi-step homologation 13:698 (-)-8-Multistriatin 14:273,274 from levoglucosenone 14:273, 274 from Scolytus multistriatis (elmbark-beetle) 14:274 synthesis of 14:273,274 (+)-Multistriatin 19:127 from levoglucosenone 14:267 synthesis of 14:267 Mulumanamana 23:653 Mulundocandin 23:343 Munchnones 1:339,340 Munjistin 26:657,663 methylester of 26:663 Munnozia maronii 26:808 Muntingia calabura L. 22:526 as antihysteric 22:526 Muqubilin 9:15,16,18-23 Muramic acid 6:388,388 2-azido-2-deoxy derivatives of 6:388,388 intramolecular reactions of 6:389,380 synthesis of 6:385-388 Muramic acid 8-1actam 6:389 1,4,5-tri-O-acetyl derivative of 6:389 Muramine 6:491,492 synthesis of 6:491,492 Muramyl peptides 6:385,404 Murashige-Skoog medium 7:91,97 Murex truncatus 28:652 (+)-Muricatacin 16:695;18:198 Muricatacin 17:252,277-279;18:195, 213-218 Muricella sp. 25:704 Murine acquired immunodeficiency syndrome (MAIDS) 25:433 Murine cancer cell lines 30:589,590 activity of (-)-deoxypodo phyllotoxin in 30:589 activity of (-)-hernone in 30:590 activity of (-)-nymphone in 30:590 activity of (-)-yatein in 30:590 activity of (+)-corytuberine in 30:589
544 activity of (+)-epiaschantin in 30:590 activity of (+)-epimagnolin in 30:590 activity of (+)-epiyangambin in 30:590 activity of (+)-hernovine in 30:589 activity of (+)-laurotetanine in 30:589 activity of (+)-magnoflorine in 30:589 activity of (+)-malekulatine in 30:590 activity of (+)-N-hydroxyhemangerine in 30:589 activity of (+)-N- formylnornantenine in 30:589 activity of (+)-N-formyldehydroovigerine in 30:589 activity of (+)-N-formylovigerine in 30:589 activity of (+)-ovigerine in 30:590 activity of (+)-ovihernangerine in 30:590 activity of (+)-vateamine-2'13-Noxide in 30:590 activity of 7-formyldehydrohernangerine in 30:589 activity of 7-formyldehydronomantenine in 30:589 activity of 7-formyldehydroovigerine in 30:589 activity of 7-hydroxy-6-methoxy1-methylisoquinoline in 30:589 activity of 7-oxohemagine in 30:590 activity of demethylsonodione in 30:589 activity of hemandonine in 30:589 activity of hernanymphine in 30:589 activity of N-hydroxyovigerine in 30:589 activity of N-methylcorydaldine in 30:589 activity of N-methylovigerine in
30:590 activity of thalifoline in 30:590 Murine cytomegalovirus (MCMV) 26:223 Murine leukemia virus LP-BM5 MuL V 30:768 cause of immunodeficiency syndrome 30:768 Murine lymphocytic leukemia 24:57-60, 69,89 Murine lymphomas L 26:1200,1210 Murine tumor cell replication 23:177 bipinnatins effect on 23:177 Murisolin 17:267;26:441,442 MurNAc 6:409,410 ~H,~3C-NMR of analogs 6:413-416 structure modification in 6:405-407 MurNAc 8-1actones 6:393 N-acetylmuramoylamide derivatives of 6:393 aminolysis of 6:393 c~-benzyl glycosidesd of 6:390,395 NMR spectra of 6:390,391 reactions of 6:390-395 stability of 6:395 [[3-MurNAc-(1 6)-Glc Nac] disaccharide 6:403 synthesis of 6:403 Murraquinone B 1:172,174 synthesis of 1:172,174 Murraya 1:172 Murrayaquinone-B 1:163,164 Musa acuminata 26:474 Musa basjoo 24:273 Musa paradisiaca L. 22:526 for epilepsy and hysteria 22:526 Musacin C 26:444 Musca bioassay 29:25 2,3-bis(trimethylsilyl) 22,25dideoxyecdysone activity in 29:27 canescensterone activity in 29:28 capitasterone activity in 29:27 cyasterone activity in 29:27 22,25-dideoxy-6(~x/[3)-hydroxy-
545
ecdysone activity in 29:27 ( 2 5R/S)2 0,2 6-dihydroxyecdysone activity in 29:27 20-hydroxyecdysone 22-acetate activity in 29:28 20-hydroxyecdysone 22-0(pyrrole-2-carboxylate) activity in 29:28 20-hydroxyecdysone 22-0(thiophene-2-carboxylate) activity in 29:28 20-hydroxyecdysone 22-0chloroacetate activity in 29:28 ,_,,-hydroxyecuys,,ne "~'~ 'q glycolate activity in 29:28 20-hydroxyecdysone 2-0cinnamate activity in 29:27 3-epi-20-hydroxy-ecdysone activity in 29:27 20-hydroxyecdysone activity in 29:27 makisterone C activity in 27 3 [3-methoxy-2 [~,14c~-dihydroxy5 [3-cholest-7-en-6-one activity in 29:27 22-O-methyl-20-hydroxyecdysone activityin 29:28 pinnatasterone activity in 29:28 polypodine B 2-O-cinnamate activity in 29:27 27-nor-2 [3,3[3,14a-trihydroxy- 5 [3cholest-7-en-6-one activity in 29:28 213,3[3,14c~-trihydroxy-5 [3cholest-7en-6-one 2,3-acetonide activity in 29:28 2 ~,3 [3,14ot-tris(tri-me thylsilylo xy)-5 ~-cho le st-7-en-6-one activity in 29:27 using Musca domestica larvae in 29:25 Musca domestica 18:698,19:124; 21:379;24:115,716;26:231 ;27:384; 29:25 Muscarin 10:394 from 2-deoxy-D-erythro pentose 10:394 from L-erythro pentose 10:394
Muscarine 21:52 L(+)-Muscarine 25:530 Muscarinic acetylcholine receptor 21:52,90 Muscarinic AchR antagonists 21:56 Muscarinic antagonist 22:19 Muscarinic receptor 21:95 ;22:18; 25:530,611 Muscarinic receptor antagonists 22:734 Muscarinic-l,2-receptor 21:95 Muscaroside C 15:200 Musci (mosses) 2:277 Muscle pain 24:898 aconitine for relieving 24:898 Musclide-A2 24:908 Musclide-A1 24:906-908 activation effects of 24:906 chemical structure of 24:908 medicinal uses of 24:906 protein kinase C activation effects 24:906 Musclide-B 24:908 (-)-Muscone 10:330,331 by three carbon ring expansion 10:330,331 (R)-Muscone 14:490 asymmetric synthesis of 14:490 synthesis of 1:632,633 via asymmetric cyclopropanation 14:490 Muscone 8:225,239,245;19:171 from Moschus moschiferus 8:219 [5,5]-Oxy-Cope rearrangement 8:247 synthesis of 8:224,242,243,247 Muscular activity 21:102 Mushroom amino acid 3:254 synthesis of 3:254 Mushroom monophenol (Omonooxygenase) 5:448 Mushroom tyrosinase 5:455 Mushrooms 1:680;17:153 Muskak 23:655 Mussaenda 25:180,183 Mustard (Brassicaceae) trypsin inhibitors 29:612 ATTI- 1 as 29:612 ATTI-A, ATTI-A', ATTI-B,
546
ATTI-C, ATTI-D as 29:612 effects on chymotrypsin 29:612 effects on trypsin 29:612 from Arabidopsis thaliana 29:612 from Brassica napus 29:612 from Brassica oleraceae 29:612 from Sinapis alba 29:612 MTI-2 as 29:612 RTI as 29:612 RTI-IIIA as 29:612 RTI-IIIC as 29:612 thrombin inhibitor as 29:612 Mustard-based prodrug 21:160 Mutagenesis 30:174 induction by xenobiotics 30:174 Mutagenic action 27:304 of human lymphocytes 27:304 Mutagenic activity 5:447;22:614;26: 675;30:750 of estrogen 5:447 of fumonisins 13:532 ofRubia tinctorum 26:675 in Ames test 30:750 Mutagenicity 7:9;22:623 Mutagenicity tests 27:303,304 Ames test 27:303 chromosome mutation test 27:303,304 for stevioside 27:303,304 forward mutation test 27:303 mammalian cell mutation test 27:304 micronucleus test 27:303 Mutagen-induced genetic variation 25:395 Mutagens 24:1061,1062 Mutamycin 5:615;13:435 Mutarotase 7:71 Mutation 30:377 in autistic children 30:377 Mutation inhibition activity 21:641 Mutatis mutandis 15:262 Muthuthi 23:658 Muurolane 15:247 et-Muurolene 21:282,283 Muurolene sesquiterpenes 21:282 Muzanzagenin 26:813,814
Muzigadial 24:182-185 synthesis of 24:182-185 Muzigodial 14:414;17:235 MVA 7:110 MVA-5-diphosphate 7:322,323 MVA-5-phosphate 7:322,323 MVAP 7:98 MVAPP 7:98 MVD assay 30:801 in vitro model 30:801 8 opioid activity in 30:801 MVD bioassay 30:807,818 [Tic2]deltorphin C activity in 30:807 in vitro 30:807,818 Myasthenia gravis 26:486 myc and c-jun pathways 25:271 cMycalamide A 5:366;10:413 Mycalamide B 10:413 Mycalamides 21:393 Mycalamides A & B 26:1231,1234 Mycalamide derivative 25:733 Mycale 25:698,727,831,892 Mycale adhaerens 15:386,19:558,613 Mycale sp. 5:366;9:19,22,24;28:712 as cytotoxic glutathione adducts 28:712 Mycalolides 25:831 Mycaminose 5:614 5-O-Mycaminosyl protylonolide 5:611, 612,615,616 Mycaminosylmcaose 5:614 Mycaperoxide 25:260 Mycaperoxide A 25:598 Mycaperoxide B 25:598 Mycarose 5:614 L-Mycarose nucleosides 4:256 Mycelia sterilia 9:203;26:482 Mycicetin-rhamnoside 22:615 Mycinamicin 5:613 Mycinolide 11:423,424 from allylic boronic ester 11:423,424 synthesis of 11:423,424 Mycinolide V 10:153 Mycoarbizins 25:781 Mycobactericum tuberculosis H37R 4:244
547
Mycobacterium 7:327;23:10;24:713, 733;26:1122 (all E) phytoene from 7:327 Mycobacterium avium 13:183;23:95; 26:1160
Mycobacterium avium-intracellulare 2:424;21:296
Mycobacteriumfallax 26:69 Mycobacterium intracellulare 2:428; 25:259
Mycobacterium leprae 9:322;23:136; 30:119 leprosols from 30:119 resorcinolic lipids derivatives from 30:119 Mycobacterium luteus 26:1122 Mycobacterium malmoense 26:1122 Mycobacterium phlei 12:103 Mycobacterium rhodochorus 25:156 Mycobacterium smegmatis 12:400; 23:474;26:227,1123,1155 Mycobacterium tuberculosis 12:398; 18:351 ;21:296;23:53 ;24:713 ;25:779; 26:1122,1155;27:284 Mycobacterium tuberculosis var. hominis 26:673 Mycobacterium vaccae 9:411 Mycoparasitism 21:223;22:74 Mycophenolic acid 22:247,259;24:549 antiviral microbial-derived compound 24:549 Mycoplasma sp. 12:48 Mycorhodin 2:139-152 Mycorrhijin A 25:782,785 Mycosamine 6:262 glycosidation by 6:276,277 in amphotericin B 6:261 Mycoses 22:60 Mycosphaerella lethalis 26:451 Mycosphaerella pinode 5:278 Mycosporine taurine 25:873 Mycothiazole 25:896;28:710 as novel lipid 28:710 anthelmintic properties of 28:710 Mycotoxicity 21:410 Mycotoxicoses 9:5 Mycotoxins 9:202-208,216;13:519; 17:475 ;21:240;24:4
Mycotoxin MT81 26:805,806 Mycotrienin 23:54 Mycotrienin I 23:75 biosynthetic building units of 23:92 related compounds 23:75 Mycotrienins 23:74 (+)-Mycotrienins I 23:78 Mycotrienins II 23:75 Mydriatics 17:395 Myeloid leukemia cells differentiation 30:498 effect of 1c~,25-dihydroxyvitamin D3 30:498 Myelotoxicity 27:436;28:559 by doxorubicin 28:562 of chitosan 28:559 of fish oils 28:559 Myelotoxicity of 5-FU 28:561 chitosan inhibitory effect on 28:561 Mylabris cichorii 27:882 Mylabris phalerata 27:882 Myles' s synthesis 30:10-12 of discodermolide 30:10-12 Mylitta lapidescens 22:527 for epilepsy 22:527 Mylosuppression 25:447,448 effect of 5-fluorouracil 25:447, 448 S-(+)-Mymontanone 15:232 Myocardial infaction 25:598 Myocardial ischaemia 25:594;26:233 Myoclonic seizures 22:508 Myodesmanones 15:231 Myodesmonoid 15:232 Myoglobin 22:327 [3H]Myo-inositol 25:487 Myo-inositol 7:181;18:391;19:352-353; 26:1155 Myo-inositol 1-phosphate 11:216,217 by myo-inositol- 1-phosphate synthase 11:216,217 from glucose-6-phosphate 11:216,217 Myo-inositol triflates 18:439 Myo-inositol- 1-phosphate synthase 11:216
548
from beef testes 11:216 from Lilium longifolium 11:216 myo-mositol 1-phosphate by 11:216,217 Myomontanoid [3-ketols 15:232 Myomontanones 15:231 Myoporone 15:228 synthesis of 15:228 R-(+)-Myoporone 15:229 Myoporum bontioides 15:229 Myoporum deserti 15:228,229 Myoporum laetum 15:236 (-)-ngaione from 15:236 Myoporum montanum 15:229 Myoporum sp. 15:227 Myoporum tenuifolium 29:579 Myosin light chain kinase (MLCK) 25:522,523,524,547 Myrcena citricolor 21:206 Myrcenes 5:343,696;7:100,101 ;11:17, 18;17:604;25:125,130,131,541,544, 593 Myrciaria dubia 22:359 Myriapoda 21:3 Myriapora truncata 17:77 Myriastra clavosa 27:879 Myrica 17:375;26:905 Myrica gale 17:371 eudesm-11-en-4-ols from 14:450 (-)-selin-11-en-4c~-ol from 14:450 Myrica gale var. tomentosa 26:895,899 Myrica nagi 17:371 Myrica rubra 17:371 ;26:895 Myrica salicifolia 22:527 for convulsions 22:527 Myricanone 26:895 Myricatomentoside 1 & II 26:899 Myricetin 5:657 22:322,331,645,661; 26:742,746,747,750,757,758,763, 770;27:746,844 ;29:573,582 effects on ACE 29:580 effects on aminopeptidase N 29:577 effects on HIV- 1 protease 29:573 effects on LELA 29:585 effects on MMP 29:582 effects on NEP 29:581
Myricetin 3-O-rhamnoside 22:615 Myricetin 3-O-rhamnoside-gallate 22:615 Myricetin-3-5'-dimethyl ether-3glycosides 5:658 Myricetin-3'-methyl ether 5:657 Myricitrin 22:166 Myricoside 22:77 Myriogloia sciurus 9:83,84 marine sterols from 9:83,84 Myriophyllum 26:359 Myriophyllum spicatum 26:378 Myriosterol 9:83,84,87 Myristic acid 5:753 Myristica fragrance 21:594;26:226,858 dihydrodiisoeugenol from 26:226 5'-methoxydehydrodiisoeugenol from 26:226 Myristoylated alanine-rich C kinase substrate 27:860,861 Myrmecia gulosa 5:223,233,254 Myrmecocystus testaceus 15:383 Myrmica 6:454 Myrmica afracticornis 5:250 Myrmica americana 5:250 Myrmica brevispinosa 5:250 Myrmica emergana 5:250 Myrmica lobicomis 5:233,235,236,254 2,5-dimethyl-3-ethyl-pyrazines of 5:222 Myrmica rubra 5:235,250,254 2,5-dimethyl-3-methyl-pyrazines of 5:222 2,5-dimethyl pyrazines of 5:222 methyl pyrazines of 5:222 Myrmica ruginodis 5:235,236,254 2,5-dimethyl-3-ethyl-pyrazines of 5:222 Myrmica rugulosa 5:235,254 2,5-dimethyl-3-ethyl-pyrazines of 5:222 Myrmica sabuleti 5:235,254 2,5-dimethyl-3-ethyl-pyrazines of 5:222 Myrmica scabrinodis 5:235,236,254 2,5-dimethyl-3-ethyl-pyrazines of 5:222 2,5-dimethyl-3-methyl-pyrazines
549
of 5:222 2,5-dimethyl pyrazines of 5:222 Myrmica schencki 5:235,254 2,5-dimethyl-3-ethyl-pyrazines of 5:222 Myrmica sp. 5:233,235,236,250,254 2,5-dimethyl-3-ethyl-pyrazines of 5:222 Myrmica sulcinodis 5:235,236,254 2,5-dimethyl-3-ethyl-pyrazines of 5:222 Myrmicaria eumenoides 27:240 Myrmicinae 6:421,422,454,455 Myrothecim verrucaria 21:235 Myrothecium hapla 26:464,474 Myrothecium roridium 21:238 wortmannin from 21:238 Myrothecium sp. 21:233 Myrothecium verrucaria 21:235 myrocin B and C from 21:235 Myrrhis odorata Scop. 15:29;27:16 Myrsinaceae 21:674 Myrsine africana 9:400 Myrtaceae 21:581 Myrtenic acid 25:154 Myrtenol 25:153 (+)-Myrtine 16:461,476-477 synthesis of 16:461,476-477 Myrtoidine 26:1053,1064,1065 Myrtus communis L. 22:527 Mysorenone-A 5:759 Mysorenone-B 5:759 Mysorenone-C 5:759 Mystroxylon aethiopium 23:659 Mytenus macrocarpa 30:659 dammarane triterpenes from 30:659 Mytilitol 18:434 Mytiloxanthione 6:152 from Halocynthia roretzi 6:152 Mytiloxantin 10:153 Mytilus edulis 6:142,143,156;17:21; 28:654 Mytilus galloprovincialis 28:654 Myxococcus xanthus 10:78,79;28:144 Myxoderma platiacanthum 15:58,75,81 3 [3,5,6[3,15(x-tetrahydroxy-5 c~stigmastan-29-oic acid from 15:81
Myxoderma platyacanthus 25:872 Myxodermoside A 15:74 Myxomycetes 29:223 as primitive organisms 29:223 chemical constituents of 29:223,225 life cycle of 29:223 plasmodium of 29:223 pyrroloiminiquinone derivatives from 29:223 secondary metabolites of 29:223 slime molds as 29:223 sterols from 29:223 Myxomycota 9:202 Myxovirus 30:408 inhibitor of 30:408
Myzus persicae
22:95;23:302;26:850,851,859, 861,862 N(10)-methyleudiotomin E 25:902 N-(p-hydroxyphenthyl) actividine 25:538 N-(p-MPS)-indole 11:315,316 2-indolylacetaldehyde from 11:315,316 N,N'-Thiocarbonyldiimidazole 25:250 N,N-Dimethyl-5-(methylthio) varacin 25:833,834 N,N-Dimethyltryptamine 25:533 N-[3-hydroxy-3-methyl-glutaroyl]tryptophan 27:480 N I,N2-Bis(7-chloro-quinoline-4-yl) phenylenen-l,2-diamine 25:346 NJ,N4,N7,N10,N:3_penta- z- coumaro ylspermidine (coumaroyl amide) 29:573 synthesis N:,NS,N:~ zccoumaroyls of permidine 29:573 N402 Schiff-base coordination complexes 25:361 Na-+,K+ ATPase inhibitor 25:535 Na+/Ca 2+ antiporters 25:517 Na+/K+-transporting adenosine triphosphate (ATP)ase inhibitor 28:670 fromAgelas nakamurai 28:670
550
Na+C1--linked monoamine neurotransmitter transporter 25:537 Naamidine A 17:17 Naamine A 17:17 (+)-Na-benzyl-20-desethylaspidospermidine 18:323 synthesis of 18:323 Nabilone 19:197 synthesis of 19:197 N-acetyl-beta-D-glucosaminidase 25:274 N-acetylneuraminic (Neu5Ac) aldolase 30:424 structure of 30:424 N-acetylneuraminic (Neu5Ac) synthetase 30:424 structure of 30:424 5-N-acetylneuraminic acid 27:104 N-acetylneuraminic acid (Neu5Ac) 420,425 catalyzed by Neu5Ac synthetase 30:425 synthesis of 30:425 nAChR 21:110;27:281 Nactrexone 30:200 3-carboxamido analogues of 30:200 N-Acyl-4-methoxy-3-pyrroline-2-ones 21:415 NAD (P)-Oz-oxidoreductase activity 25:811 NADDP receptor Ca2+channels 25:539 NADDP receptors 25:534 NADH-dependent keto-reducing activity 25:500 NADP oxidoreductase 18:55 Nadsonia fulvescens 5:290 Naftifine 2:423;22:61 Nagata hydrocyanation 11:87 Nagata's reagent 16:13 Nagilactone A 28:480 anti-feedant activity of 28:480 Nagilactone C 28:475,480 anti-fungal activity of 28:475 anti-feedant activity of 28:480 Nagilactone E 28:475 anti-fungal activity of 28:475
Nagilactone F 28:499,502 total synthesis of 28:502 synthesis of 28:499 Naja naja 22:132 Najas sp. 26:361 Nakafuran-9 6:70 by Wittig olefination 6:70 from Chromodoris maridaditus 6:70 from Hypselodoris godefroyana 6:70 synthesis of 6:69,70 Nakanishi's induced CD method 5:700 Nakanishi's method 15:190,193,194 Naked sugar 12:338;14:179 Nakmurol A 25:688 Nallanin 25:541;27:844,845 Naloxone 22:24;30:802,804,815 effect of 30:815 Namenamicin 25:837,838 Na-methyl sarpagine methosalt 13:386, 387,405 Na-methyl vellosimine 13:386 NANA (N-acetyl neuraminic acid) 13:207-210 Nanamycin A 4:591-593,609 synthesis of 4:591-593,609 Nanaomycin D 4:591-593 synthesis of 4:591-593 (+)-Nanaomycin-A 11:127-130 biomimetic 11:127-130 from 4,10-dihydro-3 H-naphtho [2,3-c] pyran- 10-one (yellow pigment) 11:127 synthesis of 11:127-130 Nanaomycins 11:127 Nantrindole 30:803,804,806 antinociceptive action of 30:816 as 6-opioid receptor antagonist 30:803 blockade of 6-opioid receptors by 30:802 effects of 30:804 Naphthacene 11:113 Naphthacene glutarate 11:123 8,13-benzo [ 1]-naphthacene quinone from 11:123
551 Claisen condensation of 11:123 with acetoacetate dianion 11:123 6,11-Naphthacene quinones 11:122,123 from anthraquinone glutarates 11:122,123 from unprotected quinone 11:123 pentacene quinone from 11:123 synthesis of 11:122,123 Naphthacenequinone 11:123 Na-Naphthalene- 1,3,8-trisulfonate 2:51 Naphthaleneacetic acid 7:90,94 as auxin 7:90,94 Naphthalenediol 11:127 from [3-hydroxyglutarate and acetoacetate 11:127 1,8-Naphthalenediol 11:131 from [3-hydroxyglutarate 11:119 Naphthalene-isoquinoline alkaloids 13:646 2-Naphthalenethiol 14:509 conjugated addition of 14:509 to enones 14:509 Naphtharazin 30:326 structure of 30:326 7H-Naphtho [1,2,3-ij] [2,7] naphthyridin-7-one 23:5 Naphtho [2.3-c] pyran-5,10-quinone antibiotics 14:271 synthesis of 14:271 Naphthocyanidine 10:106 antitumor activity of 10:104 X-ray crystallographic analysis of 10:104 Naphthofurans 7:184 [3-Naphthol 4:400 1-(3,3- dime thyla llyl)- 2-hydroxynapthalene from 4:396, c~-Naphthol 4:400 Naphthols 20:276,20:283 Naphthomycin 23:54 Naphthomycinol 23:68 Naphthomycins F 23:65 Naphthopyran antibiotics 11:127-131 by [3,[3,8,8'-tetraoxoalkane dioates 11:127-131 synthesis of 11:127-131
Naphthopyrans 4:398,400 from Tebebuia chrysantha 4:400 from Glaium species 4:400 from Tecona grandis 4:400 Naphthoquinomycin 23:54 Naphthoquinomycin C 23:67 Naphthoquinomycin H 23:67 1,4-Naphthoquinone 23:53 1,2-Naphthoquinone 26:470 4-Naphthoquinone 26:470 Naphthoquinones 4:388,389;5:3,9,10; 7:435;20:276,283;22:637;27:849; 28:408,429;29:747,750;30:320 action of 28:429 against human rhinoviruses (HRVs) 29:750 analgesic effects of 29:725 antiamoebic effects of 29:725 antibacterial effects of 29:723 antifungal effects of 29:723,725 antiinflammatory effects of 29:725 antipsoriatic activity of 29:751 antipyretic effects of 29:725 antithrombotic effects of 29:725 antitumor effects of 29:723,729 antiviral 29:750 apoptosis induced by 29:727 biological properties of 29:723 biosynthesis of 2:226 13C-NMR assignments of 29:731 catalpalactone as 29:733 catalpone as 29:733 catalponol as 29:733 chemopreventive effects of 29:725,728 cytotoxic effects of 29:723 dehydrodunnione as 29:733 dehydrodunnione as 29:733 4,9-dihydroxy-ct-lapachone as 29:734 ~-dunnione as 29:733 from Verbenaceae 29:723 IH-NMR assignments of 29:731 HMBC correlations of 29:733 1-hydroxy-2-methylanthra2R,3 R-3-hydroxy-dehydro-isoct-lapachone as 29:733
552
quinone as 29:733 hydroxydunnione as 29:733 immunostimulating properties of 29:751 insecticidal activity of 29:751 IR data of 29:730 a-lapachones as 29:733 lapachol 29:723 larvicidal activity of 29:751 leishmanicidal effects of 29:723 mechanism of action of 29:747 menaquinone-1 as 29:733 mitochondrial respiration inhibition 28:by 28:429 molluscicidal activity of 29:751 molluscicidal activity of 7:427 occurrence of 29:723 production of 29:733 redox capacity of 30:320 streptocarpone as 29:733 structure of 29:723,734 synthesis of 3:450,451 synthesis of 3:450,451 topoisomerase inhibition by 29:727 toxicity of 29:751 trypanocidal effects of 29:723 UV data of 29:730 with isovaleraldehyde 4:396,398 with isovaleraldehyde 4:396,398 wound healing effects of 29:725 Naphthoquinones 7-methyljuglone 7:423 Naphthoquinones, antiparasitic 29:747 against Trypanosoma cruzi 29:748 as antileishmanial agents 29:747 as antimalarial drugs 29:747 as TcTR inhibitors 29:748 as trypanocidal agents 29:747 Naphthoquinones, leishmanicidal activity 29:749 against Leishmania braziliensis 29:749 against Leishmania donovani 29:749 against Leishmania enriettii 29:749 against Leishmania infantum
29:749 against Leishmania major 29:749 Naphthoxirene 7:407,408,423 Naphthyl borneol 13:76 Naphthyl C-glycoside 10:379 reaction of naphtyl-O-glycoside with boron trifluoride etherate 10:379 (R)-(+)-l-(l'-Naphthyl) ethanol 13:573 1-Naphthylacetone 30:218 brominated product of 30:218 13-Naphthylamine 8:378,388 (R)-l-Naphthylethylisocyanate 13:324 Naphthyridinomycin 10:108-115 antitumor activity of 10:107 biosynthesis of 10:104-106 synthesis of 10:107 Naphthyyridine alkaloids 4:524 Naphtooxirene derivatives 7:407 antifungal activity of 7:407 cytotoxicity of 7:407 glucosides of 7:407,408 Naphtoquinones 26:638;29:232 as myxomycetes pigments 29:232 homotrichione as 29:232 trichione as 29:232 Naphtylisoquinolines 27:819 Napoleogenin B 7:141 X-ray analysis of 7:139 NAPRALERT 19:751 Naproxen 6:309 Naproxene 14:505 antiinflammatory drug 14:505 synthesis of 14:505 Napthalenones 5:754 Napthodianthrones 22:644,647,649,672, 773 Napthomycin A 9:434 Napththylisoquinoline alkaloids 26:822 Napthylisoquinoline alkaloid, 7,1 'linked 20:438-441 asymmetric synthesis of 20:438-441 Napthylisoquinoline alkaloids 20:407-451 total synthesis of 20:407-451
553
Napthylisoquinoline alkaloids, 5,1 'linked 20:420-438 asymmetric synthesis of 20:420-438 Napthylisoquinoline alkaloids, 5,8'linked 20:442-451 asymmetric synthesis of 20:442-451 Napyradiomycin B~ 25:798 Napyrodiomycins A and B 25:797,798 Narburgia stuhlmanni 1:701,702 antifeedant from 1:701,702 Narciclasine 20:325,353,356;21:97; 22:29;26:610,612,613,616 Narciclasine-4-O-D-glucopyranoside 26:610,613 Narcissus alkaloids 20:233 Narcissus pallidulus 20:234 mesembrenone from 20:234 Narcissus pseudonarcissus 20:353,359, 391 ;22:459;26:608 lycorine from 20:233 Narcissus tazetta 26:610,618 Narcotic 30:200 fentanyl as 30:200 Narcotic analgesic effect 30:200 Narcotic opiate alkaloid 30:804 Narcotine 21:80,98,108 c~-Narcotine N-oxide benzoxazocine derivative 6:468 ring expansion of 6:468 thermally-induced rearrangement of 6:468 Nardoa gomophia 15:46 Nardoa novaecale 7:298 halityklosides A,B,D from 7:298 Nardoa tubercolata 15:71 (+)-5-epi-Nardol 14:374,375 synthesis of 14:374,375 (-)-Nardol 14:374,375 from Nardostachys jatamansi 14:374,375 Nardostachysjatamansi DC. 14:375; 22:527 for epilepsy, hysteria 22:527 for convulsive affections 22:527 for hysteroepilepsy 22:527
guaiane alcohol from 14:375 (-)-nardol from 14:374 Nargenicins 17:288 biosynthesis 17:286 chemistry of 17:286 macrolides 17:283 synthesis 17:291 Naringen 25:615 Naringenin 7:207,228;22:423;25:613, 614,618,653 ;26:745,759,762,768; 28:229,288 ;29:580 biological activity of 28:229 effects on ACE 29:580 (2S)-Naringenin 28:17 aromatase inhibition by 28:17 Naringenin chalcone 23:746;25:653; 28:271 in juice 28:271 in ketchup 28:271 in tomato skin 28:271 Naringin 23:747;25:469,541,544,613, 615,618;29:573,580 effects on ACE 29:580 effects on HIV-1 protease 29:573 Naringin dihydrochalcone 27:17,34 structure of 27:64 Naringinase 7:272 13-Narin-II8-4'-Ome-eridictyol 30:207 activity in formalin test 30:207 activity in writhing test 30:207 Narirutin 22:325;23:747 Narwedine 20:359 N-aryl glycine amides 27:285 N- [(quinolizidin- 1c~-yl)-methyl]benzotriazol-2-yl 27:285 Nash-Davies media 7:97 Nasipuri and Mitra 29:212 miltirone synthesis by 29:212 Na-sulfanomido fl-carbolin 25:6 Nasutitermes ephratae 27:385 Nasutitermes exitiosus 5:702;21:277 Nasutitermes nigriceps 27:385 Natriuretic effect 26:269 Natriuretic peptides (NPs) 25:367,381 Natsucitrines I,II 13:370 from Citrus natsudaidai 13:370 Natsudain 26:752
554
Natural (-)-steganone 29:392 steganes synthesis of 29:392 Natural abundance 9:110 of 170 9:110
of 33S 9:110 of 77Se 9:110 of 125Te 9:110 Natural algicides 26:380,381 in freshwater ecosystems 26:380,381 Natural analgesic products 30:195 capsaicin as 30:195 Ag-tetrahydrocannabinol as 30:195 morphine as 30:195 Natural anthracyclines 21:157 for antibody directed enzyme prodrug therapy 21:157 for prodrug monotherapy 21:157 prodrugs of 21:157 Natural antifungals 23:340 activation of 23:129 animal sources of 23:340 fungal sources 23:347 natural killer (NK) 23:129 plant sources 23:346 prokaryotic sources 23:349 structure of 23:340 Natural bioactive alkaloids 27:778 synthesis of 27:778 Natural bolaphile 25:813 Natural bridged biaryls 29:355,356 allocolchicine as 29:355 allocolchininoids as 29:355 antimitotic properties of 29:355 as anticancer compounds 29:355 axial chirality of 29:355 axial configuration of 29:356 effects on cell division 29:355 families of 29:355 interaction with tubulin 29:355 occurrence of 29:355 rhazinilam-type compounds as 29:355 steganacin as 29:355 steganes as 29:355 structural feature of 29:355,356 synthesis of 29:355,356 Natural cyclophanes 25:757
Natural ecdysteroids 29:18
3-epi-2-deoxy-20-hydroxy-
ecdysone as 29:18 25-deoxyecdysone as 29:18 2-dehydro-3-epi-20-hydroxyecdysone as 29:18 2-deoxy-20-hydroxyecdysone as 29:18 2-deoxy-3-dehyroecdysone as 29:18 3-deoxyecdysteroids as 29:18 9,20-dihydroxyecdysone as 29:18 20E-glycosides as 29:18 generation of 29:17 shidasterone as 29:18 Natural flavonol 30:224 antioxidant properties of 30:224 kaemferol from 30:224 Natural fungicides 21:181 Natural inhibitors 20:889;27:836 of carcinogenesis 30:591 ofphosphatases 20:889 of protein kinases 27:836 Natural killer cells (NK cells) 25:273 Natural oligopeptides 27:793 with biological activities 27:793 Natural phytotoxins 26:369 Natural podolactones 28:457,484 activity in biochemical assays 30:226 7,9(11)-dienolide as 28:457 effect on HIV- 1 integrase 7ct,Sc~-epoxy-9( 11)-enolide as 28:457 inhibition 30:226 a-pirone [8(14),9(11)-dienolide] as 28:457 Natural polyphenols 30:226 allelopathic activity of 28:484 Natural product inhibitors 24:418-442 competitive with FPP 24:418-438 competitive with Ras peptide 24:438-442 farnesyl-protein transferase as 24:403-464 non-competitive 24:442-462 Natural product libraries 29:646 as economic process 29:647
555
as robust process 29:647 bioinformatics driven assessment in 29:650 biomaterial selection in 29:647 by automated solid-phase synthesis 29:647 by Eldridge et al. 29:648 by Schmidt et al. 29:649 by standardized HPLC method 29:647 by Stewart et al. 29:649 custom chromatography features in 29:649 data management in 29:647 dual extraction strategy in 29:651 economic scale-up in 29:647 from bacteria 29:646 from fungi 29:646 from invertebrates 29:646 from marine sources 29:646 from microalgae 29:646 from microbial extracts 29:648 from plants 29:646 from terrestrial 29:646 Gilson liquid handling system in 29:649 high throughput structure elucidation in 29:647 high throughput technology of 29:646 HPLC-NMR of 29:670 HPLC-NMR-MS of 29:670 of alkaloid-like compounds 29:646 of benzopyrans 29:646 of benzylamines 29:646 of chemical structures 29:671 of cosmetic agents 29:650 of drugs 29:668 of drug metabolites 29:668 of dyes 29:668 offlavone analogues 29:646 of flavonoid-like compounds 29:646 of genus synonyms 29:671 of geographic location 29:671 of herbicides 29:668 of indolyl diketopiperazines
29:646 of Latin names 29:660 ofmappicine analogues 29:646 of molecular ions 29:667 of non-redundant pure compounds 29:647 of novel pharmaceuticals 29:650 of nutraceuticals 29:650 of oligoheterocycles 29:646 of pesticides 29:668 of polyphenol 29:649 of quinazolines 29:646 of secondary metabolites 29:649 of spectroscopic databases 29:661 of tannins 29:649 of taxonomic classifications 29:671 of textual data 29:671 oftyrosinase inhibitors 29:667 of UV spectrums 29:660 ofyohimbine analogues 29:646 phytologixTM discovery program of 29:650 predictive profiling in 29:647 selection methodology for 29:649 standardized isolation process in 29:647 usng enzymology 29:650 using bioengineering 29:650 using genornics 29:650 utilizing combinatorial methodology 29:650 with electron ionization mass spectra 29:668 Natural products 17:117,747-789; 21:373 ;24:351-398,473-555 ;27:398; 28:573,617 ;29:643 ;30:55,79,191, 219,703,738 170-NMR spectrum of 17:566 anti-metastatic activity of 28:559,573 anti-obesity action of 27:398 anti-psychotic activity of 24:1116 as antiviral agents 24:473-555 anti-tumor activity of 28:559 antitumor effect of 30:55,56
556
anti-rumor-promoting activity 24:215-264 architecture of 29:644 as analgesics 30:191 as anti-hypotensive drugs 29:643 as anti-inflammatory drugs 29:643 as anti-obesity materials 30:79 as antiulcer drugs 29:643 as bioactive compounds 24:473, 475 as cyclooxygenase enzyme 29:645 as lipoxygenase enzyme 29:645 as platelet aggregation inhibitors 29:653 biological activity of 27:393,405 by cationic intermediates 12:443-496 by oxidative phenolic coupling 20:263-315 by radical intermediates 12:443-496 chirality of 7:3-28 defensive role of 30:738 dereplication of 19:747-789 effects of 30:79 from medicinal plants 27:393; 29:643 from plants 30:703 in allergic inflammation 30:55 in arteriosclerosis 30:55 in cancer 30:55 m coronary heart diseases 30:55 m diabetes 30:55 m heart diseases 30:55 m hypertension 30:55 m thrombosis 30:55 m tumor metastasis 30:55 m tumor-bearing mice 28:573 medicinal aspects of 24:351-398 pharmacological studies of 27:393 plant derived 19:747-789 ring systems in 29:644 role of combinatorial synthesis in 29:644 role of high throughput screening in 29:644
solid phase synthetic techniques in 29:644 solid-phase extractions in 29:644 stereoselective synthesis of 12:443-496 synthesis of 19:117 use of 30:191 vascular physiological effect of 30:55 with polyene amide 21:373 Natural regulation 13:257-261 of gene expression 13:257-261 by antisense RNA 13:257-261 Natural steroid 30:504,505 ergosterol 30:505 sitosterol 30:505 stigmasterol 30:505 synthesis of 30:504 Natural steroids synthesis 30:504 of vitamin D analogues 30:504 Natural therapeutic herb 30:194 as analgesic 30:194 Natural vegetable polyphenolic extract 21:622 Naturally occurring protein kinase activators 27:829 Natzahualcoyone 23:709 Nauclea latifolia 26:1036 Naucletine 3:405 synthesis of 3:405 Naufraga 27:661 Nauphoeta cinerea 9:488,489;22:378 Navanax inermis 10:152;17:28 Navelbine 26:1047,1048,1049 Navenone B 10:152 Naviculla pelliculosa 26:358 Navonones 17:28 Nazarov cyclizations 3:11 ;13:34,35 BF3-OEt2 mediated 10:412 in (+)-A9(12) capnellene synthesis 6:43 of (+)-limonene 10:412 with BF3-Et20 8:242 Nazarov reaction 14:592,611 Nazarov's reagent 14:734 Nazlinin 14:758 biosynthesis of 14:760 from Nitraria schoberi 14:759 serotonergic activity of 14:759
557
Nb-methyl suaveoline 13:402,403,411 Nb-methyl-Nb-21-secotalpinine 13:3:391 NCI assay 18:878 N-containing compounds 24:527-533 as antiviral compound 24:527-533 N-containing sugar 24:917 chemical structure of 24:917 N-demethylansamitocin P-3 23:71 N-desacetylappaconitine 25:528 NDGA 17:316 synthesis of 17:316 NDGA compound 27:692 N-difloretin-6,7-disulphate 5:648,655 FAMBS fragmentation of 5:647 Neamphine 25:897,898 Neamphius huxleyi 28:688 neamphine from 28:688 Nebramine 14:145 Necator americanus 26:425,481,494 Necic acids 19:464 synthesis of 1:260-269 Epi-et-Necrodol 16:153 Necrodol 16:153 synthesis of 16:153 c~-Necrodol 16:153 synthesis of 16:153 [~-Necrodol 16:153 synthesis of 8:279 Necrosis 26:993;27:87 in mammalians 27:87 Necrotizing agent 25:613,615 Nectandra salicifolia 20:522 Nectandrin B 26:198 Nectria coccinea 21:227 Nectria fuckeliana 15:383 Nectria gibberella 9:203 Nectria haematococca 18:709 Nectria sp. 21:224 Nectriapyrone 15:351 Nef reaction 10:464;14:39;19:120,141, 146,152,153,173 reductive 14:633,634 Negamycin 1:370-377 synthesis of 1:370-377 Negative cotton effect 4:707
Negative ion chemical ionisation (NICI) 9:468,473,475 Negishi coupling reaction 30:13 Neighboring group participation 1:204, 205 acetamide assisted displacement 1:204,205 for hydroxyl inversion 1:427,428 Neisosperma glomerata 1:124 Neisseria 12:63 Neisseria gonorrhoeae 26:673 Neisseria meningitides 4:196,206; 29:324 diheptoses in 4:196,206 Neisseria perflava 7:69 Nejkpetin 5:654 Nemalion vermiculare 26:1137 Nematocidal activity 12:396;23:840; 26:439,443,451,454,461,466,469, 470,474,482,485,887 ;28:146 against Bursaphelenchus lignicolus 12:396;23:840 of 2-desoxo- 15c~-methyl-14(xhydroxy-MFA 28:347 of 2-desoxoparaherquamide A 28:331 of eliamid 28:146 of fatty acids 26:434 Nematoctonus robustus 23:343 Nematode endoparasites 12:7 Nematodes 1:435 activity against 1:435 Nematospiroides dubius 12:3 Nematostatic activity 26:429,430 Nemerosin 26:215 Nemertilline 21:51 Nemertini 21:3 Nemorensic acid 1:263 synthesis of 1:263 Nemorosine 20:669 from Salvia nemorosa 20:669 Nemorosone 22:660 Nemorosonol 22:659,690 Nenrasapora crassa 25:304 ergosterol mutants of 25:304 Neoandrographolide (andrographolide O-glucoside) 29:587 effects on proprotein convertase 29:587
558
Neoartanin 7:224 Neoastilbin 27:18,35 structure of 27:35 Neocapillene 7:222 Neocarzinostatin 10:150,154,171,175, 190 5-Neocedranol 5:792 13C-NMR spectrum of 5:792 Neochlorogenic acid 23:744,757 Neochromes 30:530,547 formation of 30:547 Neocurdione 23:825 Neodihydrothebaine 6:478,479 from thebaine 6:479 synthesis of 6:478,479 Neoeriocitrin 23:747 Neoglycoconjugates 26:1159 Neohesperidin 22:423;23:747;26:744 Neohesperidin dihydrochalcone 15:5, 30;27:17,34 structure of 27:34 Neohesperidyl saccharide 15:20 (+)-Neohobartine 11:294,295 structure elucidation of 11:294, 295 Neohop- 12-ene 25:59 Neohop-13(18)-ene 25:65 Neohop- 13-ene 25:59 Neointermedeol 14:451,452 from Amitermes excellens 14:451,452 from Artemisia schmidtiana 14:450 from Bothriochloa bladhi 14:4510 from Bothriochloa glabra 14:450 from Bothriochloa insulpta 14:450 from Bothriochloa intermedia 14:450 from [3-eudesmol 14:453,454 from Geigeria burkei 14:450 from Subulitermes bailey 14:451,452 from Subulitermes oculatissimus 14:451 from Subulitermes parvellus spAB 14:451
synthesis of 14:450-465 total synthesis of 14:453,454 Neoipecoside 26:129 Neoisomenthol 25:155 Neoisopecoside 26:129 Neojusticin A 26:243 as PAF-induced inhibitor 26:243 Neojusticin B 26:194,235 Neolaulimalide 19:569 cytoxicity of 19:569 Neolaurallene 5:361 Neolaurencenynes 19:454 Neolemnane 10:182 7-R, 8-R Neolignan 26:571 7-S, 8-S Neolignan 26:571 Neolignan rhamnoside 5:476,477 Neolignans 5:5,459-462,464,495,797; 8:159-161 ;16:561-564;17:311; 20:631 ;24:739,740,845,847,849, 888-890;26:184,244,551 ;30:219 anti-tumor activity of 24:845, 847,849 biosynthesis of 30:219 chronic inflammation alleviation by 24:887-895 from Chosemia arbutifolia 20:640 from Eucommia ulmoides 20:647 from Salix sachalinensis 20:627,629 structure of 30:219 synthesis of 5:797 Neolitsea sericea 28:419,422 24Z-ethylidenelanost-8-en-3one from 28:422 24-methylenelanost-8-en-3one from 28:422 lanostanes from 28:422 Neolupenol 22:117 Neomenthol 17:605;25:155 Neomycin 25:925,928 Neoneptalactone 16:289 Neoolivil 26:198 2-Neopentyloxy- 1-apocamphanecarboxylic acid 12:422,423 Neopetasin 29:87 activity in PLA assay system 29:87
559
activity in 5LOX assay system 29:87 Neopinone 18:55 synthesis of 10:180 Neoplastic activity 26:452;27:306 of stevioside 27:306 Neoplastic B cells 25:270 Neoplastic cell lines 26:752 Neoplastic transformation 5:448 of BALB/c3T3 cells 5:452 Neoproaporphine intermediates 6:480 dibenz [d,f] azonine derivative from 6:480 Neorabdosin (novelrabdosin) 15:112, 137 13C-NMR of 15:154 from Rabdosia eriocalyx 15:171 from Rabdosia nervosa 15:173 ~H-NMR of 15:145
Neorautanenia pseudopachyrrhiza 7:417 Neosachaftoside 7:207,227 Neosamine C 11:217,218 Neo-sarpagine 13:386 Neoseiulus fallacis 28:434 Neosidomycin 14:143 Neosiphonia 26:1175 Neosiphonia superstes 19:596,:607; 25:731 ;26:1207-1210 Neosiphoniamolide A 26:1210 Neosmilaster georgianus 15:58 Neosolaniol 6:242 Neosolaniol derivative 6:230,232 Neospirene intermediates 6:478 dibenz [d,J] azonine derivative from 6:478 Neothalibrine 26:825,827 Neothyone gibbosa 15:92 neothyoside A from 15:92 Neothyonidioside 7:279 from Neothyonidium magnum 7:278 Neothyonidium magnum 7:278 neothyonidioside from 7:278 Neothyoside A 15:92 from Neothyone gibbosa 15:92 Neotripterifordin 23:687 Neovacularization 28:572 effect ofegosterol 28:570,572
Neoxanthin 6:133,136,141,146;7:98, 320,321;30:530 as ant repellant 6:142 stereoisomer of 6:139 Neoxanthin derivatives 6:135,136 Neoxygambirtannine 1:125,126 Neozygites adjarica 28:434 Nepeta 26:172;30:268 Nepeta cataria 4:604;6:522 Nepeta hindostana 30:268 nepitrin from 30:268 Nepetajaponica 24:273 Nepetalactam 6:522 Nepetalactone 4:604,605;7:441,442 synthesis of 4:557,558 (+)-Nepetalactone 7:7 Nepetin 30:749 structure of 30:749 Nepetin-7-sulphate 5:655 Nephropathy 24:858 Nephtea chabroli 25:708 Nephteis brasiliensis 25:875 Nephteis fasicularis 25:859;28:644 as source of fasicularin 28:644 Nephthea chabrolii 21:281 Nepodin 9:400 Neptunia antiqua 7:4 Neptunia contraria 7:4 Neral 13:333;25:125,132,133,136,137, 138 Nereistoxin 18:697 Neric acid 25:133 Nerifol 9:293,296 Nerine bowdenii 20:352 Nerinejonquilia 20:391 Nerine papyraceus 20:391 Nerine poeticus 20:391 Nerine tazetta 20:391 Neriucoumarin acid 9:293,294 Nerium oleander 9:293-315;22:527 cyctotoxic agents from 9:293-315 for epilepsy 22:527 Neriumol 9:293,295 Neriumoside 9:293,294 Nerol 25:140,143,165;28:406 acaricidal property of 28:406 Neroli oil 27:373 Nerolic acid 20:5
560
Nerolideol 23:798 trans-Nerolidol 20:588 Nerolidol 9:531;21:589;25:125,162, 163,164,166,168 ;28:406 acaricidal property of 28:406 Nerolidyl pyrophosphate 6:247,248 Nerve growth factor 12:394;26:951; 30:504 effect of K-252a on 12:394 effect of staurosporine on 12:394 role in development of neurons 30:504 Nervine tonic 23:499 bacopa monnira as 23:499 Nervosanin 15:120 laC-NMR of 15:134 from Rabdosia nervosa lfi: 173 IH-NMR of 15:127 Nervosin 15:141 13C-NMR of 15:158 from Rabdosia nervosa 15:173 ~H-NMR of 15:150 Nervous polyarthritis 26:400 (1R)/(1S)-[ 1-3H]Neryl diphosphate 11:219,220 Nerylacetone 25:162,165,166,168,169 Neryldiphosphate 11:219,220 (+)-bornyl diphosphate from 11:219,220 N-ethylscopolamine 22:735 Netimicin 25:258 Netol '7:100,101,104,107,108,125 degradation of 7:105 Netropsin 5:558,575 analogues of 5:558 binding of DNA 5:575 structure of 5:549,550 synthesis of 5:554-556 Netropsin analogues 5:558,561-563,566 synthesis of 5:558,561-563,566 Netropsinin 5:552 Netschnikowia reukaufii 5:282 Netzahualcoyene 18:777 Netzahualcoyondiol 18:777 Netzahualcoyonol 18:777 Netzhualcoyone 5:747,749;7:147-149; 18:764,765,777,778 from Orthosphenia mexicana 7:147
Neu5Ac 30:425,440,445-448,460,463, 468 approach to 30:468 biosynthesis of 30:425 from non-carbohydrate precursor 30:460 Grignard reaction of 30:445-448 preparation of 30:440,463 role of N-acetyl-D-mannosamine in 30:425 role of phosphoenolpyruvate 30:425 synthesis of 30:445-448 total synthesis of 30:460 Neu5Ac aldolase 30:425,426 isolation of 30:425 mammals 30:425 use of 30:426 Neu5Ac aldolase catalysis 30:428 synthesis of KDO by 30:428 Neu5Ac analogs 30:426 preparation of 30:426 Neu5Ac precursor 30:461 and stereospecific hydroxylation 30:461 Neu5CBz 30:426 Neural catarrh 26:50 Herniaria hirsuta in 26:50 Neuralgia 30:203 use of ginseng root in 30:203 Neuraminic acid 11:466;16:105; 27:103-152;30:420 biological activity of 27:103-152 effects of 27:105,106 chemistry of 27:103-152 deaminated form of 30:420 Neuraminidase 16:75,93,105,106,107; 27:103,107,108,112-116 enzyme mechanism of 27:114 from viruses 16:108 inhibitor of 16:95,111 of bacteria 16:112 of influenza virus 27:114 target against influenza infection 2"/:103 Neuraminidase inhibitors 27:130 4-amino-3-nitrobenzoic acid 27:138 4-(N-acetylamino)-3-
561
guanidinobenzoic acid 27:138 4-amino-3-hydroxy benzoic acid 27:138,139 calyceramide A as 28:713 I-(4-carboxy-2-(3-pentylamino)phenyl)-5,5-(hydroxymethyl) pyrrolidin-2-one 27:150-152 2-deoxy-2,3-didehydro-Nacetylneuraminic acid 27:130,136 2,3-didehydro-2,4-dideoxy-4guanidyl-Neu5Ac 27:131,135 Neuraticidal 24:866,867 bioassay of 24:866-867 Neurite outgrowth activity 30:505 in hypothalamic neurons of rat 30:505 in neurons 30:505 of dictyosterol 30:505 of natural product 30:505 Neuritis 26:50 Herniaria hirsuta in 26:50 Neuritogenic activity 28:720 of Cucumaria echinata 28:720 Neuroblastoma 26:924,927 cell differentiation of 26:927 Neuroblastoma development 26:754 Neurochemical pathway 30:374 of autistic spectrum disorders 30:374 Neurodegeneration 30:224 role of free radicals in 30:224 Neurodegenerative disease 22:67 Neuroexcitatory activity 26:479 Neurogenic pain 30:205 induction by formalin 30:205 inhibition by incarvillateine 30:204 Neuroharmonal transmitter 22:15 Neurohormones 27:794 Neurokinin A 27:800 Neurokinin B 27:800 Neurokinin NKI receptor 30:203 interaction with ginseng 30:203 Neurolathyrrism 25:529 Neuroleaena lobata 26:808 2,3-Neurolenin 26:808 Neurolenin A&B 26:808,809
Neuroleptic drugs 26:270 Neuromuscular activity 21:152 Neuromuscular blocker 24:875,880-883 as biological action 24:875 effect ofcoclaurine as 24:887 glycyrrhizin as 24:151,880-883 paeoniflorin as 24:878-880 Neuromuscular blocking action 24:875-925 effect of cyclohexylidene on 24:883-887 of Kampo medicines 24:875-926 of N-methyl isocorydine 24:856 Neuromuscular blocking activity 24:851 Neuromuscular blocking effect 24:898-899 of aconite 24:898-899 of hypaconite 24:898-899 Neuromuscular blocks 22:58 Neuromuscular synapse 24:877-887 effect beta-eudesmol of 24:883-887 effect coclaurine of 24:887 effect cyclohexylidine of 24:883-887 effect glycyrrhizin of 24:880-883 effect medicinal plants of 24:877-887 effect paeoxiflorin of 24:878-880 effect p-phenylene-polymethylene bis-ammonium of 24:883-887 Neuron cell 27:806 Neuronal activity 30:376 in amygdala 30:376 role of human serotonin transporter gene (SLC6A4) in 30:376 Neuronal cell 28:315 crocin's effect on 28:315 Neuronal differentiation 30:368 effect of serotonergic neurotransmission on 30:368 Neuronal excitability 30:194 role of cannabinoids 194
562
Neuronal functioning 30:378 serotonin action on 30:378 Neuronal signal transduction 21:5 Neurons 30:367 Neuropathological studies 30:376 in autistic brains 30:376 Neuropatic pain syndromes 30:193 use of capsaicin in 30:193 Neuropeptide analogues 27:798 Neuropeptide FF 22:25 Neuropeptide receptor 25:688 Neuropeptide Y 21:72;27:800 Neuropeptides 9:493-495;25:387 from marine invertebrates 9:493-495 Neuroplant 22:692 Neuroprotective properties 28:173,177 of Ginkgo biloba L. 28:173,177 Neuropsychiatric disorders 24:1093-1134 natural product-derived treatment of 24:1093-1134 Neuroreceptors 21:89 alkaloids with 21:3-111 Neurospora crassa 5:277-279;8:297; 22:477;26:228,1016,1128 Neurospora sp. 30:528 neurosporaxanthin from 30:528 Neurosporaxathin 30:517 structure of 30:517 Neurosporene 7:30-354;20:588 cyclization 7:330-329 from 7,8,11,12-tetrahydro-qJ,Wcarotene 7:330-329 lycopene from 7:330-329 (9Z,7'Z,9'Z)-Neurosporene 7:335 from (9Z, Z,9')-carotene 7:332 (7Z,9Z,7'Z,9'Z)-lycoptne from 7:332 Neurotensin 27:799,800 Neurotoxic shell 21:300 Neurotoxicity 26:965,1004 HK-Neurotoxicity 26:993 Neurotoxin alkaloids 1:385 Neurotoxins 17:3 Neurotransmitters 21:5;22:25;25:516; 30:367 serotonin as 30:367 Neurotransmitter antagonists 25:515
Neurotransmitter converting protein 25:512 Neurotransmitter degradation 30:377 by monoamine oxidase (MAO) 30:377 Neurotransmitter receptors 25:512 Neurotransrnitter signalling 25:517 Neurotransmitter transporting protein 25:512 Neurotransmitter-gated ion channels 25:519 Neurotrophic activity 23:469;24:854 28:174,177 in neural injury 28:174 of Ginkgo biloba L. 28:177 of Magnolia liliflora 24:854 ofS-alkyl cysteines 23:469 Neurotrophic agents 24:1060 Neurotropic factors (NTFs) 504 in maintenance of nerve cells 30:504 role in survival of nerve cells 30:504 Neutraceuticals 25:597 Neutral lipid 30:788 Neutrophil cytosol 27:842 Neutrophiles 22:437 Neutrophils respiratory burst inhibitor 28:16 broussoaurone A as 28:16,17 Newbouldia leavis 22:527; 29:747 for convulsions in children 22:527 N-formyl methionyl-lucyl-phenylalanine (FMLP) induced superoxide 25:47 N-formyl-catharinine 27:778 NF-~cB activation 25:470;30:206 effect ofparthenolide 30:206 NF-•B assay system 29:89 3-acetoxycosmnolide activity in 29:89 2c~-acetoxy- 14-hydroxy- 15-isovaleroy-loxy-9-oxo-costunolide activity in 29:89 9ct-acetoxy-4[3,15-epoxymiller1(10)Z-enolide 15-Acetoxy-9cthydroxy-8 p-methacryl-oyloxy14-oxo-acanthospermolide
563
activity in 29:89 15-acetoxy-9ot-hydroxy-8 [3methacryl-oyloxy- 14-oxoacantho spermolide activity in 29:89 NF-~:B Nuclear factor kappa B 25:470, 711 (-)-Ngaione 15:236 from Myoporum laetum 15:236 N-Glycoylneuraminic 30:427 synthesis of 30:427 Ngouniensine 1:55 biogenesis of 6:503 NHAc 30:421 structure of 30:421 N-Heterocyclic ring 27:782 aromatization of 27:782 Niacinic acid 26:968 Nic-l,10,11,17 20:182 Nic-l-lactone 20:242 Nic-2 lactone 20:215,224 Nicalbin A 20:180,242 Nicalbin B 20:181,242 Nicandra physaloides 20:248;25:300 Nicandra steroids 20:180,182 Nicandrenone 20:181 Nicandria physaloides 20:238 Nicasterol 9:36,37,43 biosynthesis of 9:43 from Calyx nicaeensis 9:37 Nicholas reactions 3:83,84 Nichora's method 12:175 Nickel boride 3:472 desulfurization with 3:472 Niclosamide 7:428 Nicotiana alata 29:610 Nicotiana glauca 29:604 Nicotiana glauca x N. Langsdorffii 29:609 Nicotiana glutinosa 7:101,110;23:343; 29:605 sclareol from 7:121 Nicotiana langsdorffii 29:604 Nicotiana plumbaginifolia 26:1146 Nicotiana rustica 22:742 Nicotiana setchelli 1:662 Nicotiana sylvestris 29:609
Nicotiana tabacum 1:671;20:135; 21:661;22:527;25:665,666;26:1145; 28:400;29:609,611 for convulsions 22:527 furostanol triglycosides from 21:661 Nicotianamine 29:578 effects on ACE 29:578 nitrogen compounds 29:328 against Candida genus 29:328 against genus Pseudomonas 29:329 against methicillin-resistant strains 29:331 against Selenastrum capricornutum 29:329 against Staphylococcus aureus 29:331 apoptotic activity of 29:333 cytotoxicity of 29:329 effects on bacteria 29:328 glycopeptide antibiotics as 29:332 herbicide resormycin as 29:329 Nicotina sp. 7:124,126 nicotine synthase from 11:204, 206 Nicotinaldehyde 21:147 Nicotinamide adenine dinucleotide phosphate (NADPH) 27:405 Nicotinamide coenzyme 17:481 R-(+)-Nicotine 22:12 (S)-Nicotine 11:204,206 biosynthesis of 11:204,206 by nicotine synthase 11:204,206 from nicotinic acid 11:204,206 S-(-)-Nicotine 22:12 Nicotine 21:51,98,110;22:10,508,724; 26:487;27:284 (-)-Nicotine 22:17;27:281 (+)-Nicotine 22:17 Nicotine l'-N-oxide 22:12 Nicotine N-glucuronide 22:12 Nicotine synthase 11:204,206 from Nicotina sp. 11:204,206 Nicotinic acetylcholine 21:14,51 Nicotinic acetylcholine receptor 18:695
564
Nicotinic acetylcholine receptor 21:51, 90;22:16;25:528 Nicotinic Ach receptor 21:21 Nicotinic acid 11:204,206;21:147; 26:965 (S)-antabine from 11:204,206 by nicotine synthase 11:204,206 (S)-nicotine from 11:204,206 Nicotinic receptor 21:102 Nicotinic toxins 18:697-699 Nicrophorus americanus 22:81 Niddanolide 11:162-164 NIDDM 21:458 Nifurtimox 26:792 Nigakihemiacetal-A 23:314 Nigakihemiacetal-D 23:314 Nigakilactone-E 23:313,314 Nigakilactone-L 23:314 Nigella satvia L. 29:694 Nigeran 5:299,310 antitumor activity of 5:317 Nigericin 3:58 Nigroporus durus 13:305 Nigrospora oryzae 26:227 Nigrospora sphaerica 21:721 Nikkomycin X 22:63 Nikkomycin Z 22:63 Nimbidin 9:296;26:815 Nimbocinone 9:297,298 Nimbolide 26:815 Nimocinolide 9:297-299 Nimolicinoic acid 9:297,298 Nine-carbon sugars 4:179 by ascent of sugar series 4:179 osmylation of 4:180-182 synthesis of 4:179 Wittig olefination of 4:180 Nine-membered rings 3:77 by Claisen rearrangement 3:77 by intramolecular DielsAlder/ozonolysis 3:79,80 by ring expansions 3:76 from 1,3-diol monotosylates 3:73,74 synthesis of 3:73,111;6:472-482 by ring contraction 6:474-482 of ring destruction 6:475,482 by ring interconversion 6:472-482
Ningalins 23:242 Ninhydrin 10:258 Niphates erecta 25:717 Niphates sp. 25:732 Niphatevirin 25:717 Nipoglycosides A, B, C, D 15:55 Nippostrongylus brasiliensis 22:401; 25:815,896;26:465 kalihinol Y from 26:465 NIR absorption spectra 30:549 of canthaxanthin 30:549 of lycopene 30:549 ofphytoene 30:549 of radical anions 30:549 of [3-carotene 30:549 Niranthin 17:318 synthesis of 17:318 Nirtetralin 26:195,237 Nirurine 5:49-51 Nishimura's catalyst 6:80,81 Nishizawa complex 16:665 Nisia nervosa 22:401 Nisia strovenosa 22:401 Nitensidines A-C 20:488 Nitidine 4:544;13:656;14:770;21:89; 22:27 antileukemic activity of 14:769 biological activity of 27:179 from pseudoberberine 14:775, 776 synthesis of 4:544;14:775-777 Nitrabirine 14:742,743 Nitramidine (dehydronitrarine) 14:759 biosynthesis of 14:760 (+)-Nitramine 14:541 from Nitraria sibirica 14:541 via Sharpless asymmetric epoxidation 14:544 (-)-Nitramine 14:544 from L-prolinol 14:544 Nitramine 14:731,762 biomimetic synthesis of 14:748-750 biosynthesis of 14:748 13C-NMR of 14:742 diastereoslectivity in 14:743-747 enantioselectivity synthesis of 14:743-747 from L-prolinol 14:743-747
565
from Nitraria sibirica 14:743 IH-NMR of 14:742 Nitraraine 14:764,765 biological activity of 14:759 biosynthesis of 14:765 cardiovascular activity 14:764 from (S)-glyceraldehyde 14:765 synthesis of 14:765 Nitraramine 14:755,756 biomimetic synthesis of 14:755,756 biosynthesis of 14:754,755 biosynthesis retroanalysis of 14:754,755 from Nitraria schoberi 14:750 via Diels-Alder reaction 14:751-754 stereochemistry of 14:752 synthesis of 14:751-754 X-ray analysis of 14:750 Nitraria alkaloids 14:731-768 synthesis of 14:731-768 Nitraria kornarovii 14:762 isokomarovine from 14:762 komaroine from 14:762 komarovicine from 14:762 komarovidine from 14:762 komarovine from 14:762 komarovinine from 14:762 nitramarine from 14:762 tetrahydro-komarovinine from 14:762 tetrahydronitramarine from 14:762 tetramethylene tetrahydro-[3carboline from 14:758 Nitraria schoberi 1:125 isonitrarine from 14:759 nazlinin from 14:758 nitramidine from 14:759 nitraramine from 14:750 nitrarine from 14:759 schoberine from 14:757 schoberidine from 14:759 spiroalkaloids from 14:742 Nitraria sibirica 14:541 isonitramine from 14:541 nitramine from 14:541
(-)-sibirine from 14:541 spiroalkaloids from 14:542 Nitraria sp. 14:742-765 Nitraria tangutorun 25:20 Nitrarine 14:731 biological activity of 14:759 biomimetic synthesis of 14:761, 762 biosynthesis of 14:760 retroanalysis of 14:761,762 Nitrate reductase-dependent NO production 26:930 Nitrate reductases 24:999-1001,1005 enzymatic activity 24:999-1001, 1005 Nitrene insertion 1:8,9,167 Nitric oxide 25:470,477,598;26:909, 911-914 as mediator of antitumor immune response 26:921-923 as signal in plant defense response 26:937-949 as plant growth regulator 26:934, 935 bioactivity of 26:909,911-914 role in cell apoptosis 26:925,926 role in cell differenciation 26:926 Nitric oxide production inhibitor 28:16 broussoaurone A as 28:16 Nitrile oxide cyclization 12:20-22 intramolecular 12:20-22 isonitramine by 14:745 Nitro C-glycoside 10:394 from Seebach silyl nitronate nitroaldol 10:394 stereoselective cyclization of 10:394 synthesis of 10:394 Nitro [3-C-glycoside 10:394 from Seebach silyl nitronate nitroaldol 10:394 stereoselective cyclization of 10:394 1-(2-Nitro) phenylethyl ester 27:332 4-Nitro- 1,2-phenylenediamine (NPD) 23:475 (E)- 1-Nitro- 1-pentadecene 19:118 3-Nitro-l-propylallolactoside 27:521
566 3-Nitro- 1-propyl-13-D-gentiobioside 27:521 (S)-5-Nitro-2-pentanol 19:155 2-Nitro-4-methyl-phenol 8:300 Nitroaldol (Henry) condensation 1:408, 409,417,418;19:159 KF catalysed 1:417,418 Nitroaldol reaction 1:427,428 2'-Nitroangelicin 23:380 p-Nitroanilide 30:834 hydrolysis of 30:834 p-Nitroaniline 21:162;27:520 Nitrobenzene oxidation assays 25:666 2-Nitrobenzenesulfonyl chloride 1:443,444 conversion of alcohols to chloride 1:443,444 o-Nitrobenzyl 4:302 as protecting group 4:302 4-Nitrobenzyl bromide 6:513,514 quaternization by 6:513,514 Nitroblue tetrazolium reduction 20:515 Nitrocyclitol 7:157 Nitrocyclitol diglycoside 7:157,158 Nitrocycloalkanones 8:244c~Michael addition of 8:244 2-Nitrocyclopentadecanone 19:172 11-Nitrodaunomycinones 14:23 (Z)- 1-Nitrodec-4-ene 19:124 c0-Nitroesters 19:133 Nitrogen compounds 29:328 armentomycin as 29:328 avoparcin as 29:332 benzoxazines as 29:343 chloptosin as 29:333 chlorocardin as 29:328 4-chlorothreonine as 29:328 chlorpeptin as 29:332 clazamycins as 29:343 complestatin as 29:332 depsipeptides as 29:329 enduracidins A as 29:332 glutamic acid analgues as 29:328 glycopeptide antibiotics as 29:332 herbicide resormycin as 29:329 leucine antimetabolites as 29:328
neopyrrolomycin as 29:343 neuroprotectins as 29:332 pepticinnamines as 29:329 pyrrolomycin A as 29:343 streptopyrol as 29:343 structure of 29:330 vancomycins as 29:331 Nitrogen inversion 1:369 of quinolizidines 1:387 Nitrogen Kagan's ether analogue 30:216 3,4-dihydroxyphenylserine as 30:216 Nitrogen oxides 25:665 Nitrogen sugar inhibitors 7:41-48 Nitrogen ylide 1:249 Nitroindole condensation 11:437,438 Nitroketone 6:447,448 cyclization of 6:447,448 2-C-Nitromethyl nucleosides 4:252 2-Nitromethylene nucleosides 4:251, 252 Nitronate addition 1:505 Nitrone 1:230,254,277 1,3-dipolar cycloaddition of 1:230,254,277 dibenz [c,g] azonine derivative from 6:474,475 from cis (trans) canadine Noxide 6:474,475 photolysis of 6:474,475 synthesis of 1:230 Nitrone cyclization procedure 14:737 Nitrone cycloaddition 1:37-375;12:290, 291 asymmetric 1:374,375 intramolecular 14:744 nitramine synthesis by 14:744 Nitrone-based synthesis 6:442 Nitrone-olefin 11:283 1,3-dipolar cycloaddition of 11:283 intramolecular 11:283 10-Nitronoracronycine 20:796 9-Nitronoracronycine 20:796 Nitro-olefins 12:411,413 alkoxides 12:411,413 2-amino alcohols from 12:411,
567 413 Michael additions of p-Nitrophenyl 1,4-dithiomaltotrioside 8:344,351 X-ray data of 8:351 p-Nitrophenyl 1-thiogalactopyranoside derivative 8:341,342 o-Nitrophenyl 1-thio-13-Dgalactopyranoside 8:315 o-Nitrophenyl 4-O-triflylgalactoside 8:343 o-Nitrophenyl 4-thiomaltoside 8:350, 351 p-Nitrophenyl glycosides 7:56 o-Nitrophenyl S-c~-D-glucopyranosyl-(1 4)-S-4-thio-et-D-glucopyranoside (Onitrophenyl 4,4-dithio-maltotrioside) 8:341,342 Nitrophenyl thiogalactoside 7:48 [3-galactoside inhibition with 7:48 o-Nitrophenyl a-maltoside 8:350 o-Nitrophenyl [3-D-galactopyranoside 8:315 4-Nitrophenylcarbonate 21:170 p-Nitrophenylchloroformate 21:166 4-Nitrophenylchloroformate 21:168 p-Nitrophenylethyl 4:285 p-Nitrophenyl-N-acetyl-f3-D- glucosaminide (NAG) 7:415,417 3-Nitropropanoic acid 15:351;19:117 biological activity of 19:117 Nitropropionic acid-glucose derivatives 25:190 3-Nitropropyl-gluosides 25:190 selniferous derivatives 25:190 4-Nitroquinoline-l-oxide 23:536; 25:937 4-Nitroquinoline-N-oxide 24:218,261, 263 Nitroquinoline-N-oxide 26:271 Nitrosamine 25:65 Nitrosine 7:232 N-Nitroso bis(2-oxopropyl) amine 27:795 [4+2] Nitroso cycloaddition 1:378 Nitroso Diels-Alder reaction 1:378,380, 381,383
intramolecular 1:385-392 Nitrosobenzene 9:573 Nitrosoglutathion (GSNO) 26:948,951 N-Nitrosopyrrolidine 6:439,441 alkylation of 6:439,441 C-Nitroso-sugar 23:68 C-Nitro-sugar 23:68 S-Nitrosylation 26:914,924,925,939 Nitzschia palea 18:698 Nitzschia pungens 21:302;26:479 N-Linked glycans 10:499 N-linked glycosylation 27:256 NMDA 21:5,19,95 NMDA receptor 21:19,70;22:667 NMDA receptor-mediated responses 25:966 NMDA-induced currents 28:319 in hippocampal neurons 28:319 N-Menthene 25:152 N-Methyl chloropyrrole 25:761 N-Methylamino-L-alanine (L-BMAA) 25:529 N-Methyl-D-aspartate binding glutamate receptors 25:529 N-methylhomatropine 22:739 N-methylmaysenine 21:445,446 synthesis of 21:445,446 N-methylmitomycin C (porfiromycin) 13:433 N-methylmorpholine-N-oxide 16:323 as cooxidant 16:323 N-methyl-N-nitrosurea (MNU) induced colon tumors 25:46 N-methylscopolamine 22:738,739 NMMNO method 19:277 N-monosubstituted formamides 12:113 dehydration of 12:113 isocyanides from 12:113 NMR 9:93-161;13:334-337;24:137, 138;30:550 application of 30:550 isotopic analysis by 13:334-337 of chalcogens 9:109-126 of saponins 24:138 structure elucidation by 9:127-161 NMR analysis 27:343 ofabscisic acid 27:343
568
NMR data 4:60-67,69,70 of Aspidosperma alkaloid analogues 4:60-67,69,70 NMR signals 30:587 of (-)-hernone 30:587 NMR spectra 18:534-546;25:435; 30:718 of Baccharis oxide 30:718 of brassinosteroid metabolites 18:534-546 of disaccharide lactone 6:395 of disaccharide methylester 6:395 ofMurNAc 8-1actones 6:390,391 of oligosaccharides 17:128 of steroid epimers 17:131 2D-NMR spectral analysis 21:764 NMR spectroscopy 7:29;21:403,579 NMR studies in structure elucidation 26:1040 2D NMR techniques 21:767 N-N'-dimethyl-4-desmethylene bicylomycin 12:68-70 synthesis of 12:68-70 N-nitro-L-arginine methyl esters 25:595,598 N-nitrosodiethylamine 25:66 NNK-induced lung tumorigenesis 25:65 "No name" lactones 10:17-25 NO synthase inhibitor 25:595 NO + 2:6 reaction with alkenes 2:6 reactions with hydrocarbons 2:4,5 Nobiletin 23:747;26:746,752 Nobilisitine A&B 26:610,619 Nobotanin A 23:404,409 Nobotanin B 23:411,405 Nobotanin C 23:404 Nobotanin E 23:404 Nobotanin F 23:404,409 Nobotanin G 23:405 Nocamycin 14:97 from Nicardiopsis syringae 14:98 Nocamycin A and B 21:412 Nocamycin I and II 21:411 Nocardia 9:433,434;25:153;26:451
Nocardia aerocolonigensis 5:55;21:263 rebeccamycin from 21:263 Nocardia aeroligenes 1:3 Nocardia brasiliensis 23:94 Nocardia interforma 10:587 Nocardia lactamdurans 22:263 Nocardia mediterranei 9:431,433,435, 440,441 ;23:54,55,57,93 rifamycin S from 12:37 rifamycin W from 12:39 Nocardia uniformis 12:118 monocyclic [3-1actams from 12:118 Nocardicine A 12:118,119 synthesis of 12:118,119 3-Nocardinic acid 12:118 synthesis of 12:118 Nocardioides 17:285;25:719 Nocardiopsis dassonvillei 12:366,367 TAN-999 from 12:366,367 Nocardiopsis sp. 5:55 Nocardiopsis sp. K-252 1:4 Nocardiopsis sp. K-252a 12:366,368 K-252a from 12:366,368 Nocardiopsis sp. K-290 12:366,368 K-252b from 12:366,368 K-252c from 12:366,368 K-252d from 12:366,368 Nocardiopsis ~?' ngae 14:97,98 nocamycm from 14:97,98 Nociceptors 30:191,193 activation of 30:193 in periphery 30:193 Nocodazole 22:462 Noctiluca miliaris 5:353;21:260 Noctuidae 18:772 Nocturnal epilepsy 22:513,521-522 Cocculus sermentosus for 22:517 Herpestis monniera for 22:513 Flemingia strobilifera for 22:521 Hemidesmus indicus R. for 22:522 Morinaga oleifera for 22:526 Nodakenetin 23:351 Nodifloretin-7-sulphate 5:655 Nodosin 15:173 from Rabdosia longituba 15:173 from Rabdosia nervosa 15:173
569
Nodososide 7:296-297,300;15:76 from Pentaceraster alveolatus 7:298 from Protorester nodosus 7:295 6-epi-Nodososide 7:300 from Pentaceraster alveolatus 7:298 Nodularia sp. 9:496 nodularin from 9:496 Nodularia spumigena 20:894,896; 27:880 Nodularins 9:498,18:269 from Nodularia species 9:496 dihydronodularin from 9:496 biological activities of 20:896, 897 biosynthesis of 20:899 chemical structure of 20:894-897 structure-activity relationship 20:897-899 synthetic approaches for 20:899-902 inhibition of protein phosphatases by 20:903 three dimensional structure of 20:903-907 molecular dynamics simulation of 20:907-910 Nodusmicin 4:620 biogenesis of 4:620 Nodusmicin activity 17:290 against Staphylococcus aureus 17:290 Nodutin (ENOD) 25:379 NOE 21:692,744,745,760,762 NOE difference experiments 6:140,163; 11:303,304;19:398 of enukokurin 2:226 of marchantin A trimethyl ether 2:104,105 oligosaccharides 17:129 NOE effects 19:398 NOE experiment 23:338,623 ofabscisic acid 27:338 ofteucrolivin A 23:623 ofteucrolivin B 23:623 of teuflavin 23:623 ofteupestalin A 23:623 NOESY 23:27
NOESY experiment 30:582 of (+)-N-formylovigerine 30:582 NOESY interactions 30:587 of (-)-6'-hydroxyyatein 30:587 of (-)-hernone 30:587 NOESY measurements 21:235 NOESY spectrum 2:63,64,272;10:268, 269 ofsacculaplagin triacetate 2:83 Noformycin 5:554 Nogalamycin 4:345,358;14:47,48 absolute configuration 4:355 synthesis of 4:330,355-357 synthesis of DEF fragment 4:359 Nogalamycin congeners 14:76 antitumor activity of 14:76 Nogalamycines 4:330 synthesis of 4:330 Nogalamycinone 4:358 construction of DEF rings 4:358 synthesis from arabinose 4:355, 356 7-dis-Nogalarol 14:86 Nogarene 14:47 (+)-Nogarene 14:65-68 total synthesis of 14:65-68 Nojigiku alcohol 16:147 synthesis of 16:147 (+)-Nojigiku alcohol 4:676 Nojirimycin 6:351 ;42,50;11:267 enzymatic aldol condensation 10:535,536 from Bacilus 10:524 from Bacilus amylocique faciens 10:524 from Bacilus polymyxa 10:524 from Bacilus subtilis 10:524 from Streptomyces ficellus 10:524 from Streptomyces lavendulae 10:524 from Streptomyces nojiriencis 10:524 from Streptomyces roseochromogenes 10:524 glucoamylase inhibitors of 10:525 c~-glucosidase inhibitors of 10:526
570
~-glucosidase inhibitors of 10:526 glucosidases inhibiton with 7:41 invertase inhibitors of 10:526 synthesis of 10:529-538 takadiastase inhibitors of 10:525 trehalase inhibitors of 10:526 Nojirimycin analogues 7:70 sialidases inhibition by 7:42 Nojirimycin C-glycoside disaccharide 10:390,391 by Wittig reaction 10:390,391 with tetra- O-benzyl-D-glucose 10:390,391 Nojirimycin hiptitol derivatives 7:42 ot-glucosidase inhibition with 7:43 Nomamyrmex esembecki 5:250 NO-mediated apoptosis 26:943 in animals 26:943 NO-mediated intramolecular disulfide formation 26:914 Nomenclature 7:318 of carotenoids 7:318 Nominal mass 2:26 NO-modulated transcription factors 26:946 (5E, 8Z)-3-9( 1-Non- 8-enyl)- 5-(E)- 1prop-l-enyl] pyrrolizidine 6:446 in Celaner antarcticus 6:445, (-)-Nonacetic acid 10:341,423 from 2,3-unsaturated C-glycofuranosyl 10:341,423 synthesis of 10:341,423 Non-acetylenic ot-ketols 6:153 optical purity of 6:153 Nonactic acid intermediate 1:600,601 synthesis of 1:600,601 Nonactic acids 3:58;18:229-268 synthesis of 3:228 Nonactin 10:424 Nonactin-potassium thiocyanate complex 18:229 Nonaene chromophore 30:526 Nonanal 28:406 acaricidal property of 28:406 7-Nonanolide 13:311,312 Nonaols 15:74
Nonaribonucleotide 4:302 1,3Z,5Z,7E-Nonatriene 21:306 Nonblue 26:1271 Non-cicosanoid mediators 27:693 Non-classical cannabinoids 30:195, 197,198 group of cannabinoid receptor ligands 30:197 Non-classical [3-1actams 12:112 Non-covalent peptide 18:918-920 Non-cytotoxic prodrugs 21:158 Non-eicosanoid mediators 27:693 (Z)-3-Nonen- 1-yl-anion synthon 19:122 Non-enveloped viruses 30:627 adenovirus 30:627 poliovirus 30:627 Nonenzymic 27:81 induced linoleic acid oxidation of 27:81 unsaturated epoxy hydroxy acids by 27:81,82 Non-flavonoidal alkaloids 21:124 Non-holostane triterpenoids 28:600 bivittoside B 28:600 kuriloside C 28:600 psolusoside B 28:600 Non-insulin-dependent diabetes mellitus 25:534 Non-isoprenoid 9:313-381 phenolic lipids from 9:313-381 Nonitol 11:464 synthesis of 11:464 Non-legume,non-cereal Bowman-Birk protease inhibitor homologues 29:600 Ananas BI-I, BI-II, BI-III, BI-IV, BI-V, BI-VI as 29:600 BBI-homologue as 29:600 effects on bromelain 29:600 effects on cathepsin 29:600 effects on cathepsin L 29:600 effects on chymotrypsin 600 effects on cysteine proteases 29:600 effects on elastase 29:600 effects on papain 29:600 effects on thrombin 29:600 effects on trypsin 29:600 fromAnanas comosus 29:600
571
fromHelianthus annuum 29:600 from Solanum tuberosum 29:600 Helianthus BBI SFTI-1 as 29:600 potato BBI as 29:600 Nonmeningeal crytococcosis 2:423 Non-metastatic cells 16:76 Non-nitrogenous acetonylchromone 21:139 Non-nitrogenous steroidal saponin 23:573 C37-Norcarotenoids 23:178 Norsegoline 23:270 Nortrewiasine 23:70 Non-NMDA binding glutamate receptors 25:529 Non-NMDA receptors 25:519 Non-nucleosides 20:533 Nonofuranose 11:458 synthesis of 11:458 Non-phenolic linear diarylheptanoids (type 1) 26:883,884,905 Non-protein aspartic protease inhibitors 29:571-575 inhibition of pepsin by 29:571 phenolics as 29:571 terpenes as 29:571 Non-protein cysteine proteases inhibitors 29:575 against common cold (rhinovirus) 29:576 against rheumatoid arthritis 29:576 from Fusarium compactum 29:575 from Hakea gibbosa 29:576 from Solanum tuberosum 29:593 ginsenoside Rh-2 as 29:576 in clinical trials 29:576 triterpene sulphates as 29:575 Non-protein inhibitors 29:575 against common cold (rhinovirus) 29:576 against rheumatoid arthritis 29:576 from Fusarium compactum 29:575 from tlakea gibbosa 29:576 ginsenoside Rh-2 as 29:576
in clinical trials 29:576 ofcystein proteases 29:575 triterpene sulphates as 29:575 Non-protein metallopeptidase inhibitors 29:577-583 alkaloids as 29:578 from natural sources 29:577 phenolics as 29:577 terpenes as 29:578 Non-protein serine protease inhibitors 29:584-590 from natural sources 29:585 phenolics as 29:584 terpenes as 29:585 Non-small cell lung cancer 23:293 Non-specific DNA damage 26:1004 Non-specific immune response 26:923 Non-specific immunity 24:140-142,146 Non-specific immunomodulators 23:129 Non-steroidal anti-inflammatory drugs (NSAIDs) 25:610;30:192,744, 752 clinical use of 30:192 use in dental surgery 30:192 use in headache 30:192 use in osteoarthritis 30:192 use in rheumatism 30:192 Non-sugar fraction 27:409,410 biological activity of 27:409,410 Non-terpenoid-type alkaloids 5:111 5-hydroxytetrahydroxyharmane 5:111 5-hydroxytryptamine 5:111 tetrahydroharmane 5:111 Non-trichothecene secondary metabolites 13:519-551 of Fusarium 13:519-551 Non-tumorigenic 30:593 JB6 precursor cells as 30:593 Nonulosonic acid 11:466;30:421 preparation of 11:466 Nonulosonic acid analogues 30:426 formation of 30:426 role ofhexoses 30:426 2-Nonulosonic acid derivatives 30:467 Non-volatile constituents 26:297-301 of saffron 26:297-301
572
14-t-Nonylphenol 9:37 sulphurisation of 9:372 (+)-Nootkatone 13:300;16:239 from (+)-valencene 13:300 (-)-Nootkatone 16:267 Nootkatone 25:128,170,171 Nopalea coccinellifera 20:734 Nopaline 21:185 NO-participation 26:936,937 in antioxidant cellular systems 26:936,937 (+)-Nopinone 16:235,239 (1R)-(+)-Nopinone 19:190,207 (S)-(-)-Nopinone 19:207 Nor-Adrenaline 15:328;22:668,669; 25:530,595 ;30:192,204,377,627,787 as hyperforin inhibitor 30:627 effect of monoamine oxidase (MAO) 30:377 inhibition of hypotensive effect of 30:787 re-uptake inhibition by DPHD 30:204 Nor-Adrenergic imidazoline receptors 25:530 Nor- or bisnorditerpenoids 28:454 nagilactone C 28:454 nagilactone E 28:454 oidilactone C 28:454 Nor thomasterolA 15:48 24(+)-3-epi- 18-Nor- 18,19-dihydroantirhine 14708 by alkaline decarboalkoxylative cyclization 14:708 from tetrahydropyridine 14:708 28-Nor-22,23-diepibrassinolide 16:344 24-Nor-25-hydroxy-vitamin D3 9:515 Nor-6,7-secoangustilobine 9:178 23-Nor-6-oxodemethyl pristimerol 7:147,148 23-Nor-6-oxopristimerol 7:147,148,150 Noracronycines (6-hydroxypyrano [2,3,c] acridin-7-ones) 13:348,357,359; 20:793 Noradrenaline release 30:787 from sympathetic nerve fibers 30:787 Noradrenaline-induced lipolysis 30:83 activation by caffeine 30:83
(+)-Norallosedamine 13:475,476 Norambrenolide 20:692 from Salvia yosgadensis 20:692 Norambrienolide ether 26:394 (+)-Noraporphines 16:509 Norartocarpetin 28:226,230 anti-human immunodeficiency virus (HIV) activity of 28:226 biological activity of 28:230 D-Noraspidospermane skeleton 19:114 Norathyriol 25:543;27:902 Norbelladine 20:325,347,359 Norbixin 20:726 5-Norborne-2-one 13:557 Norbornene 6:76,77 (• from 6:76,77 trans-5-Norbornene-2,3-dicarbox ylic acid 8:153,154 (+)-(R)-5-Norbornene-2-carboxylic acid 8:148,149 (IR)-5-Norbornene-2-one 8:148,149 synthesis of 8:148,149 (+)-Nb-Norbuxupapine 2:189,190 structure of 2:189,190 Norcapillene 7:222 Norcaradine 13:32 Norcardia 10:153;21:436,442 machecin I and II from 21:486 Norcardia alba 25:162 Norcardia argentisis 17:283 Norcardia mediterranei 21:421,425 Norcarene derivative 1:567 photoinduced preparation of 1:567 Norcaronols 6:36 in poitediol synthesis 6:36 Nor-carotenoids 30:516 Norcepharadione-A 20:481 Norcepharadione-B 20:481 synthesis of 3:439,440 Nor-C-fluorocurarine 1:36 synthesis of 1:40,46-48 Norcitronellol 19:83 Norcoclaurine 13:662 S-Norcoclaurine 18:53 Norcodeine 22:10 Norcoradiene cycloheptatriene-type electrocyclic rearrangement 6:72,73
573
in dihydrospiniferin 1-synthesis 6:72,73 5,15-Norcorrinoids 9:598 17-Norcrassin 8:29,30 (+)-Norcyclomicrobuxeine 2:195,196 strcuture of 2:195,196 Nordamnacanthal 26:641,657,663,673 Nordibromonitrile 21:307 Nordidemnin B 10:257,271 synthesis of 10:294-298 Nordihydroguairaretic acid (NDGA) 26:191 Norditerpene 9:16,17,21 3E,5Z-Norditerpene diene 9:24,25 Norditerpenes 17:11 Nordlihydroguaiaretic acid 22:126 Nordostachysjatamansi DC. 22.'527 Norectal 27:483 Norephedrine 21:57 (R,S)-(-)-Norephedrine 22:14 Norepinephrine 9:579;21:95;22:19; 25:516,536,537,538 a-subtype 8:395 [3-subtype 8:395 synthesis of 8:395-406 Norepinephrine-augmenting lipolytic activity 27:400 ofoolong tea 27:400 Noreugenin 4:382,384;21:124,148,149 6,8-diprenylnoreugenin from 4:382,384 prenyl bromide with 4:382,384 6-prenyl noreugenin from 4:382, 384 8-prenyl noreugenin from 4:382, 384 Norficisterol 9:579 Norfluorocurarine 5:123 ;9:190-192 (+)-Norglaucine 16:508 Norhalichondrins A 5:378,380,382,383 Norhalichondrins B 5:378,381,382 Norhalichondrins C 5:378,381,382 Norharman 5:353;21:80,84,96,97; 25:531 Norhebesterol 9:40,41,43 Norhyoscyamine 17:398 7-Norisocrassin 8:29,30 Norisoflavone 17:19
Norlabdane diterpenoids 20:692 from Salvia yosgadensis 20:692 Norlignans 30:222 as diarylethanoid derivatives 30:222 structure of 30:222 Normacusine B 5:124;9:171;13:386, 400,401,429 Normal-phase HPLC 21:537 Normelicopicine 13:352,363-365,368, 378 Normelionine F 1:127;26:1060 (+)-Normetazocine 16:478 synthesis of 16:478 (+)-Normorphinandienones 16:505 Nomicotine 16:427;22:12 synthesis of 16:427 Nomomanone 20:74 Nomuciferine (51) 27:880,881 Noroleanane saponins 7:139 from Clemisia petrici 7:138 Noroxymorphone 18:47,48 Nor-pachoulenol 25:171,172 (+)-Nor-patchoulenol 4:674 Norpinguisanolide 20:469 Norpinguisone 2:227,228 Norplicacetin 4:244 Norpluviine 20:351,20:352,20:356 Norpontevedrine 3:439,440 synthesis of 3:439,440 (R,S)-(-)-Norpseudoephedrine 22:14 Norreticuline 11:205 (-)-Norreticuline 18:86 Norrish cleavage 8:207 ofalkylphenacyl sulfides 8:207 Norrish II reaction 8:128-131 of gibberellin aldehyde ester 8:128-131 Norrish II process 7:147 Norrish reaction 20:74 Norrish type 1 photo-cleavage 19:35 upon UV irradiation 19:35 Norrish type II photocyclization 14:659-664 Norrish type II photofragmentation 14:659-664 in carbohydrate 14:659-664 Norrish type II reaction 4:419,420; 14:645-665
574
Norrisolide 17:12,13 (+)-Norruspoline 13:476 Norsalanodione 19:135 Norsecurine 10:155 Norsecurinine 10:153;14:657 Norsesquiterpene 25:163,166 Norsesterpene 9:16-18,25 Norsesterpene cyclic peroxides 9:15,16, 18,22 3E,5Z-Norsesterterpene diene 9:24,25 (i)-Norsolanadione 19:135 Norswertianoline 22:541,533 Norterpene 9:15-33 biosynthesis of 9:15-33 marine 9:15- 33 Norterpene cyclic peroxides 9:15-33 19-Nortestosterone 5:449,450 Northern blotting analysis 15:449 (+)-Nortrachelogenin 26:270 Nortrachelogenin 5:522;26:192,233 O-glucosylation of 5:531-533 O-methylation of 5:531-533 Nortrachelogenin methyl ether 5:531-533 O-glucosylation of 5:531-533 O-methylation of 5:531-533 Nortrachelogenin-di-[3-D-glucoside 5:522 Nortracheloside 5:522,532 O-glucosylation of 5:531-533 O-methylation of 5:531-533 N-Nortropacocaine 1:383-385 synthesis of 1:383-385 Nortropane 22:721,732 Nortropine 1:378 Norushinsunine 21:79 Norvaline 21:297 (S)-Norvaline 13:512 D-Norvaline 19:18 Norysca 30:609,610 NOS inhibitors 25:471 NOS-dependent NO production in plant cells 26:931-934 Nostoc commune 21:275;26:362 Nostoc linckia 19:587;21:303;25:794 Nostoc NSW 26:95/10 26:367 Nostoc sp. 9:496-499;25:789;26:352, 366,372
Nostoc sphaericum 12:366,370
indolo [2,3 a] carbazoles from 12:366,370 Nostocyclophane D 25:794 Nostocyclophanes 25:757 Nothenia anomala 26:440 Nothenia brasiliensis 26:446,463-465, 471,483-485,487,488,492,493 Nothenia dubius 26:432,463,471 Nothogenia fastigiata 26:1138;30:403, 408 anti-influenza activity of 30:408 xylomannans from 30:403 Notholaena affinis 5:678-680 Notholaena aschenborniana 5:676,681 Notholaena californica 5:677-679 Nothomyrmecia macrops 5:233 Notodoris citrina 17:17 Notodoris gardineri 17:18 Notoncus ectatommoides 5:224,230,254 Notopterygium incisum T. 29:696 Novalal 25:152,153 Novel analgesics 30:206 target of 30:206 Novel gallic acid derivatives 30:208 design of 30:208 Novobiocin 26:366 Novoimanine 30:628 antimicrobial activity 30:628 fl-N-oxalylamino L-alanine (L-BOAA) 25:529 Noyori BINAL-H reagents 10:22-24,37 Noyori procedure 11:96 Noyori Ru-BINAP catalyst 13:503 Nozaki reaction 12:13 intramolecular 12:13 Nozaki-Hiyama reaction 30:24 Nozaki-Kishi coupling reaction 30:8, 10,11 Nozaki-Oshima methylenation 6:185 Nozaki-Oshima reagent 6:189 deuterated 6:189 Nozaki's reagent 14:637 NPAA 21:20,70 N-phenyldehydronoraporphine 16:516 (+)-N-pivaroyltetrahydroisoquinoline 16:512 n-Propyl 2-propenethiosulfinate 23:467
575
NSAIDs (classical) 30:192 effects on COX enzymes 30:192 side effects of 30:192 N-substituted NeuAc derivatives 30:427 preparation of 30:427 N-sulfonation 11:291 of 3-indolyacetic acid 11:291 N-Terminal extracellular 22:20 N-tosylated phenylalanine derivatives 30:216 conversion of 30:216 Nuciferin 21:70 Nuclear factor kB 25:598 Nuclear Overhauser Effect (NOE) 2:57-77 ;21:690;27:335 ofabscisic acid 27:336 Nuclear Overhauser experiments 5:3 of artemisinin 5:26 of eupatorenone 5:29 of 10-hydroxy- 11-methoxydracaenone 5:18 of lareantin 5:10 ofprionitin 5:31 Nuclear sterol regulatory element binding protein nSSREGP 25:388 Nuclease 13:271,288,289 Nucleating scaffold proteins 25:335 Nucleobase 19:511 Nucleoidin glucoside 25:781 Nucleophile 16:399 Schollkopf type 16:403 Nucleophilic addition 16:439;19:527 2-amino alcohol by 12:411,413 of 2-1ithio-3,3-diethoxy- 1-propen with N bulc 12:36 of ketonucleosides 19:527 of organolithium reagents 12:411,413 of c~-alkoxydimethyl hydrazones 12:411,413 to a-amino aldehydes 12:411, 414 intramolecular 16:439 to carbonyl compounds 12:36 by allyltin derivatives 11:442, 443 by carbanion reagents 11:439-443 by vinyl carbanions 11:440,441
of chiral ot-keto acetals 4:330-332 of nonylmagnesium bromide 19:493 Nucleophilic agents 19:121 Nucleophilic conjugate addition 4:479 to 2-(1 '-hydroxyethyl) propenoates 4:479 Nucleophilic displacement 19:68,191 intramolecular 16:426 ofallylic acetate 16:426 Nucleophilic epoxidation 19:167 Nucleophilic substitution 14:438-445 Lewis acid-mediated 14:484 of acetals 14:484 Nucleoside analogues 20:532 Nucleoside antibiotics 1:397-431 synthesis of 1:397-431 Nucleoside phosphoramidites 4:272, 273,291 synthesis of 4:272,273,291 Nucleosides 4:221-265;24:527-533 as antiviral compound 24:527-533 hexopyranose Nucleotide 9:605 Nucleotide-gated ion channels 25:527 Nudibranchs 17:105;21:358-361 isocyanides in 21:358 isothiocyanates in 21:358 Nudiposide 26:195 Numida meleagrus 5:836 hemoglobin components of 5:836 N-unprotected Neu5Ac 30:427 preparation of 30:427 Nuphar indolizidine 1:292 synthesis of 1:292 Nupharin C 23:402 Nyssaceae 23:405 (+)-Nupharolutine 13:488,489 synthesis of 13:488,489 Nutrient media 2:366,367 Nutrients bioavailability 27:312,314 Nutritional benefits 23:775 of phenolic antioxidants 23:775 N-vanillyl-N-(3-acyloxy-2-benzylpropyl)-thioureas 30:201 as vallinoids 30:201
576
(+)-Nyasol 26:230,231 as antiprotozoal agent 26:230 Nyctanthes arbortristis 26:807 Nymania-1 20:492 (-)-Nymphone 26:199,212;30:569,590 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 26:212; 30:589 Nymphs 22:401 Nypa fruticans 7:176 Nysson spinosus 5:225,231,251,253 (R)-(O)-benzylglycidol 13:624 O, O-dimethylmalekulatine 30:584 from (+)-malekulatine 30:584 O, O-dipropylphosphoroselenoic acid ester 30:529 OA-antibiotics 4:434 in carbapenem 4:434 2,3,4,6-Tetra-O-acetyl- 1-thio-ot-Dglucopyranoside 8:319 Oat carcinoma of lung 1:276 Obaberine 26:824,826 Obavatifol 26:202,219,220 O-B enzylhydroxylamine 22:295 Obesine 20:370 Obesity 27:398;30:79,80,83 gold thioglucose (GTG) in 27:398 model of 27:398 role of oolong tea 30:80 use of orlistat (Ro 18-0647) 30:83 Oblongolide 15:473 Obovaten 26:202,219 Obovatinal 26:219, 26:220 Obsessive compulsive disorder 30:368, 369 effect of circadian activity on 369 role of serotonin (5-HT) 30:368 Obtusifoliyl linoleate 9:461 Obtusifuluol 9:39 from cycloeucalenol 9:39 Occelasterol 9:41 (+)-Occidol 16:214
Occupational asthma 30:337 carmine use for 30:337 Oceanapamine 25:706 Oceanapia sagittaria 25:894 Oceanapia sp. 21:260,269;25:706,894; 28:713 dithiocyanates from 28:713 pyridoacridine alkaloids from 21:254 nematocidal activity of 28:713 thiocyanatin A from 28:713 thiocyanatin B from 28:713 thiocyanatin C from 28:713 Ocetaxel 25:245 Ochnaceae 7:408 Ochraceolide 697 20R-Ocotillone 23:546 20S-Ocotillone 23:546 Octanol 23:341 1Octocorallia 23:153 Odorless garlic 23:465 Oenothein A 23:418 Oenothein B 23:404,410 Oenotheins 407 Oil-macerated garlic 23:466 Oleanane 23:692 Oleanolic acid 23:535,707 Oleoeuropein 23:746 Oligorization 23:403 Oligostilbenoid vaticaffinol 23:538 Oligostilbenoids 23:531,534,547 Ochratoxin A and D 15:388 Ochratoxins 15:387,388 from Aspergillus ochraceus 15:382 Ochrobirine 1:199,200 synthesis of 1:199,200 (-)-Ochropposinine 14:565 from piperidine 14:565 synthesis of 14:565 Ochrosia elliptica 6:521 epchrosine from 6:521 Ochtodenes 5:343 Ocillatoria spongeliae 21:310 c~-Ocimene 21:582 [3-Ocimene 7:95;21:582;28:406 acaricidal properties of 28:406 cis-Ocimene 21:600 trans-Ocimene 21:600
577
Ocimene 25:125,130,131 Ocimenone 25:143,144 Ocimum 29:579 Ocimum americanum L. 22:527 Ocimum americanum var. pilosum 30:256 vicenin-2 from 30:256 Ocimum basilicum L. 5:473,474;7:108, 109;22:392,527 ;27:374,376 for epilepsy 22:527 Ocimum grandiflorum 30:256 isothymusin from 30:256 Ocimum gratissimum L. 22:527 Ocimum kenyense 21:595,617 Ocimum micranthum 28:400 Ocimum sanctum L. 21:616;22:527; 29:572 Ocimum sp. 29:572 Ocimum suave 22:527 Ocotea foetens 26:850 Ocotillol-type saponins 21:672 5,9-Octacosadienoic 25:721 (9E,12Z)-Octadecadienoate 9:566 (9,12Z)-Octadecadienoic acid (linoleic acid) 9:560 Octadecane-l,2,3,4-tetrol 5:704 L-ribo-Octadecane- 1,2,3,4-tetrol 5:705, 707 L-xylo-Octadecane- l ,2,3,4-tetrol 5:705,707 Octadecanoic acid 26:361 Octadecanoids 1:528 Octadecyl ferulate 26:666 Octadecylsilane 21:530 Octadecyne-6 2:14 CI (NO) mass spectrum 2:14 3,7-Octadien- 1-ol 12:467,468 stereoselective synthesis of 12:467,468 (3E)-3,7-Octadien- 1-ol 2:466,467 stereospecific preparation of 2:466,467 Z-Octadocene-6 2:7 CI (NO) spectrum 2:7 (1R,2S,3R,4aS,7R,8S, 8aS,9aR)Octahydro- 1,2,7,8-tetrahydroxy-3[(1R)- 1-hydroxy ethyl]-6hydroxymethyl-pyrrolo-[2, l-b] benzoxazole 10:506
Octahydro- 1H-[ 1]-benzopyrano-[4,3,2,e,f]-isoquinolines 18:81 Octahydro- 1H-benzo furo- [3,2,-e ]isoquinolines 18:81 Octahydro-5-oxoindolizine- 1,28-triol 12:328 Octahydro-benzazecine 6:483 synthesis of 6:483 Octahydrobenzofuran 12:10,11 from cyclohexanone 12:22-24 (+)-Octahydrodeacetyldebromolaurencin 10:233 trans-Octahydroflavopereirine 1:143 synthesis of 1:143 Octahydroflavopereirines 1:133,134 synthesis of 1:133,134 Octahydroindolizine 11:229;12:275 (1S,2R,8R,8aR)-Octahydroindolizine1,28-triol 12:313 from Astagalus emoryanus 12:313 from Metarhizium anisopliae 12:313 from Oxytropis sericea 12:313 from Rhizoctonia leguminicola 12:313 from Swainsona canescens 12:313 synthesis of 12:313-325 Octahydroindolizine- 1,2-diols 12:303-306 Octahydroindolizine- 1-ol 12:278 Octahydroindolizine-2-ols 12:283,284 synthesis of 12:283,284 Octahydroindolizine-7-ols 12:285-289 Octahydroindolizine-8 c~-ols 12:300-303 (-)- 1,2,3,4,6,7,12,12b-Octahydroindolo [2,3-c~] quinolizine 12:383 Octahydroisoquinoline 12:457 diastereoslective synthesis of 12:457 from 6-hydroxy-4a-aryl-transdecahydro-isoquinoline 12:457 Octaketides 9:267;21:211 Octalactin 25:728 Octalactin A and B 25:728 trans-Octalin 6:13,14 (-)-polygodial from 6:13,14 Octalin coupling reagent 13:586
578
cis-Octalone 6:550,551 dimethylsulfoxonium methylide addition to 6:550,551 (+)-Octalone 6:552-554 [3.3.0]Octan-2-one derivative 10:412 Octandecanoid pathway 25:374 Octanedioic acid derivative 11:117 tetraoxoalkane dioates from 11:117 Octanoic acid 21:197 Octanol 21:589 (R)-y-Octanolide 13:310 8-Octanolide 13:312 Octant rule 2:167;9:255,743,18:623,628 in 5cz-cholestan-3-ene 2:168 in citronellal 2:168 for conjugated ketones 2:168 for cyclopropyl ketones 2:168 for c~-halogeno ketones 2:168 for oxido ketones 2:168 Octa-O-acetyl 1-thiomannosyl disaccharide 8:319,321 Octa-O-acetylated 2-thiosophorose 8:327 Octa-O-acetyl-cz-D-mannopyranosyl 1thio-cz-D-mannopyranoside 8:321 Octa-O-acetyl-f3-f3-manno-trehalose derivative 8:319-321 from 2,3,4,6-tetra-O-acetyl-[3-Dmannopyranosyl chloride 8:319-321 synthesis of 8:319-321 Octapeptide bromocontryphan 21:320 Octapeptides 9:487-489 Octapetide patellamide 25:878 Octatrienal 6:292,293 pentaene from 6:292,293 Octa- O-acetyl- 1-thio-a, ec-trehalose 8:318,321 6-Octen- 1-al 14:506,507 RH(I) catalyzed 14:506,507 stereoselective cyclization of 14:506,507 2-Octen-l-ol 13:304 1-Octen-3-ol 13:304,326 Octocorallia 21:272
Octolasion tyrtaeum 30:828 from Lumbricidae family 30:828 Octopamine 21:57 Octopus vulgaris 28:647 Octose derivatives 11:462-464 synthesis of 11:462-464 Octosyl acids 1:398 synthesis of 1:422-431 Octotea pretiosa 19:117 S-(+)-Octoteine 16:506 Octulosonic acid 11:466;30:421 preparation of 11:466 Octulosonic bicyclic precursors 30:473 synthesis of 30:473 Octyl-13-D-glucopyranoside 18:832 Octyl-13-D-glucopyranoside micelles 18:838 Odakaic acid 5:384,385,388 ODN analogues 19:539 Odonicin 15:171,176 from Rabdosia eriocalyx 15:173 from Rabdosia longituba 15:173 from Rabdosia nervosa 15:173 Odonticin 5:66,204 ~H-NMR spectrum of 5:205 Odonticinin 5:66 13C-NMR spectrum of 5:209 ~H-NMR spectrum of 5:209 Odontin 5:204,66 Odontinin 5:208,66 Odontomachus brunneus 5:223-225, 237,254 Odontomachus clarus 5:224,228,254 Odontomachus hastatus 5:224,228,254 Odontomachus sp. 5:221,232,225,228, 237,238 Odontomachus troglodytes 5:223-225, 237,238,254 Odor perception 21:580 Odoracin 26:465 Odoratin 27:499 Odour substances 27:378 activity of 27:378 ODS column 27:351 Oebalus pugnax 22:401 OECD and ICH 27:304 ofmutagenesis test 27:304 Oenothera biennis 23:404;29:573, 581,589
579
Oenothera erythrosepala 23:404 Oenothera laciniata 23:404 Omphalia lapidescens 23:140 Oncomelania hupensis 23:537 Oestrogen 25:516 Oestrogenic activity 28:257,293,302 ofAc-SAMM 2 23:31 of agrimoniin 23:429 ofalienanin B 23:429 ofalysine B 23:634 ofalysine D 23:634 ofalysine E 23:634 ofbacopasaponin A 23:509 ofbacopasaponin B 23:509 ofbacopasaponin C 23:510 ofbacopasaponin D 23:510 of bidentatin 23:609 of BZSAM 23:31 ofBZSAMM 1 23:31 of casuarictin 23:428 of corilagin 23:428 of3-deacetylalysine B 23:634 of6-deacetylsandrasin A 23:624 of 2-deoxychemaedroxide 23:609 ofellagitannin oligomers 23:428 of 7-epi-eudesm-4(15)-ene1[3,6c~-diol 23:635 of 7-epi-eudesm-4(15)-ene1[3,613-diol 23:635 of lO-epi-teuclatriol 23:635 of7-epi-teucrenone B 23:637 of 12-epi-teucvidin 23:601 ofeuphorbin F 23:429 ofgemin A 23:429 of gnaphalin 23:614 ofheterophylliin B 23:429 of 3[3-H-neo-clerodanes 23:607 of 11-hydroxy-valenc 1(10)-ene2-one 23:635 oflaevigatin B 23:429 of leuvicenone I 23:631 of natural products 24:215-264 ofnobotanin F 23:429 ofnobotanin G 23:429 ofnupharin A 23:428 of plant compounds 28:257,302 of Podophyllum extracts 26:169
of polyphenols 28:293 of pecaresidins A acetate 23:195 ofpecaresidins B acetate 23:195 of pedunculagin 23:428 ofplectrinone A 23:631 of rearranged diterpenoids 23:629 ofrugosin D 23:429 ofrugosin F 23:429 of SAM 23:31 of SAM MM1 23:31 ofSAMM 1 23:31 of SAMM 2 23:31 ofsandrasin A 23:624 ofsandrasin B 23:624 ofsanguiin H-6 23:429 ofsanguiin H-10 23:429 of sesquiterpenoids 23:633 stachyulrin 23:428 of strictinin 23:428 oftellimagrandin I 23:428 of teuchamaedrin C 23:618 of teucladiol 23:635 of teuclatriol 23:635 ofteucrolivin A 23:624 of teucrolivin F 23:626 of teucvidin 23:597,599 ofteucvin 23:597,599 of teuflavin 23:622 of teuflidin 23:597,599 of teuflin 23:596,599 of teuhetone 23:637 ofteuhetone A 23:637 ofteupernin A 23:607,610 of teupernin B 23:610 ofteupestalin A 23:622 ofteuvlncenone A 23:631 ofteuvlncenone C 23:631 ofteuvmcenone E 23:631 of teuvmcenone F 23:631 ofteuvlncenone G 23:631 of teuvlncenone H 23:631 of vaticaffinol 23:544 of verrucosin 26:228 of vescalagin 23:428 of villosin A 23:631 of villosin B 23:631 ofvillosin C 23:631 of woodfordin A 429
580 Officigenin 7:140 from Guaiacum officinale 7:139 Offord method 9:541 electrophoretic mobility 9:541 OG 25:98,99 antihepatotoxic effect of 25:98,99 antiviral activity of 25:114 Ogebikase 25:654 O-Glycoside 10:344,370-380 intramolecular rearrangement 10:379 stereoselective synthesis of 10:340 OH scavenging activity 22:316 24-epi-l ct,25(OH)2D2 30:494 binding affinity of 30:494 1,25(OH)2D3 calf thymus receptor 30:496 competitive binding to 30:496 lct,25(OH)2D3 metabolites 30:495 1a,25(OH)2D4 30:495,499,500,501,504 synthesis of 30:501 9-no r- 9-0 H-he xahydrocannab ino 1 (HHC) 30:195,196 structure of 30:197 type of non-classical cannabionoid 30:197 Ohno's cyclization method 4:466,467 Ohno's lactone 8:148,149 synthesis of 8:148,149 Ohtsuk-Tahara synthesis 14:677,678 of taxodione 14:677,678 6or- 14a-OH-withanone 20:205,20:220 Oidiodendrolide B 28:475 anti-fungal activity of 28:475 Oidiodendron griseum 28:454 Oidiodendron truncatum 28:454 Oidiodendrum griseum 28:472 terpenoid dilactones from 28:472 Oidiodendrum truncata 28:475 Oidiolactone C 28:505 synthesis of 28:505 Oidiolactones 28:475 antifungal activities of 28:475 Oils 9:529-536 of Artemisia species 9:529-536
Oishi's macrocyclic lactam contraction 12:187 Okadaic acid 17:19;19:128;20:896,897, 907,908;21:301 ;25:9,10,731,832; 27:875,876 from dinoflagellates 25:543 Okadaic acid-induced TNF-a-gene expression 25:470 Okenone 7:339,361 Olacaceae 22:720 for hysteria 22:720 Old world cutaneous leishmaniansis 2:314 cause of 2:312 Olea 29:589 Olea capensis 5:514 Olea europa 3:254 Olea europaea L. 5:505,515,521,523, 524,531,7:427,477;29:586;587 Oleacein 29:581 effects on ACE 29:581 Olean-12-en-3[3,1 ltx-diol 5:747 Olean- 12-ene 22:100 Olean-12-ene sapogenol 7:161,163 anodic oxidation of 7:161,163 Olean- 12-ene-3fl,23,28-triol 25:60,64 18a-Olean-12-ene-3fl,23,28-triol 25:64 Olean- 12-ene-3fl, 23,28-triol tri-Ohemiphathalate sodium 25:65,66 Olean- 12-ene-3fl-23,28-triol 25:60 18a-Olean-12-ene-3fl-28-diol 25:60 Oleanane 9:267 Oleanene acylated bidesmosides 21:675 Oleanane glucuronoide 25:89-92,94,121 Oleanane saponins 25:183,203 Oleanane triterpenes 7:131-174 Oleanane triterpenoids 25:60 Oleananes 22:94;25:64 arjunolic acid 25:64 Oleanane-type saponin 21:662,665, 666,655,674;25:207 Oleanderol 9:293,294 Oleanderolic acid 9:293-295 Oleandomycin 5:613 Oleanen-28,30-dioic acids 7:145 Oleanene glucuronosides 25:117 Oleanene-28-oic-acid-3-Omonodesmosides 21:675
581
Oleanene-type triterpene saponins 25:103 9'-Oleanoglycotoxin-A 7:428 molluscicidal activity of 7:428 Oleanolic acid 2:129;7:134,154,189, 429,430,432,434;9:51,55,57,293; 20:6;21:651,656,665 ;24:132;25:59, 61,107,541 ;29:575;30:697,718,719 antiviral activity of 17:135 against carrageenan edema 17:138 3-epi-oleanolic acid 15:281 from Eremophila caerulea 15:281 from Eremophila platycalyx 15:281 from Salvia divaricata 20:702 from Salvia glutinosa 20:707 from Salvia montbretii 20:704 from Salvia nemorosa 20:702 from Terminalia alata 7:134 structure of 30:718 Oleanolic acid 3-O-glucuronide 25:106, 107,108 Oleanolic acid 28-O-glucuronide 25:106,107,108 Oleanolic acid-type glucuronides saponins 25:106 hepatoprotective effect of 25:106 Oleanolic glycosides 17:126-127 Oleanyl cation 25:181 Olearia paniculata 25:255 Oleficin 28:135 antibiotic activity of 28:135 Olefin 12:151,152 reduction of 12:151,152 with high stereoselectivity 12:151,152 oxidative cleavage of 30:43 cis-Olefin 14:569 benzylation of 14:569 from propargyl alcohol 14:569 trans-Olefin 14:570 E-allylic alcohol from 14:570 benzylation of 14:570 Olefin conjugation 1:442 with DBU 1:442 Olefin cyclization 1:655-673 biomimetic 1:655-673
using mercury (II) triflate/amine complex 1:655-673 Olefin isomerization 4:49 ofallyl acetates 4:49 with Pd (MeCN)2 C12 4:49 Olefin metathesis 3" 18 Olefin stain 12:207 Olefin-arene photocyclization 3:28 Olefinic dioxolane acetal 14:471 cyclization of 14:471 from (2R,3R)-2,3-butanediol 14:471 Olefin-ketocarbene cyclization reaction 6:41 in (+)-isocycloeudesmol synthesis 6:41 Olefins 1:451,453;4:503,504;7:390, 9:315;13:313;27:749,752 conversion to chlorohydrins 1:451 isomerization 1:453 with Rh (PPh3)3 C1 1:453 halogenation of 27"749,752 Oleic acid 11"192,193;25:333;26:434 30:56,64,65,66,68,69 antitumor activity of 30:56 biosynthesis of 11" 192,193 effect on DNA synthesis in LLC cells 30:68 effect on liver metastatic tumor colonies 30:66 effect on matrigel-induced capillary-like tube network 30:68 effect on spleen weight 30:66 from carp oil 30:65 in Cladosporium eladosporioides 11"194 in Penicillium brefeldianum 11"192 inhibition of tumor growth by 30:64 inhibitory actions of 30:69 Matrigel-induced angiogenesis (in vivo) 30"69 Oleiferin-B 26:228,230 Oleiferin-F&G 26:228,230 Olentes 17:200 Oleoresin 10:3,26
582
Oleoside 26:319 1-Oleoyl-2-acetylglycerol 12:390 1-Oleoyl-2-acetyl-rac-glycerol 12:397 induced platelet aggregation 12:397 Oleoylacetylglycerol 25:536 D-Oleoylphosphatidylcholine 25:333 Di-Oleoylphosphatidylethanolamine 25:333 Oleum chenopodii 20:12 Oleuropein 7:442,472;26:324,334,343 partial synthesis of 7:471 Oleuropic acid 25:141 Olfaction 25:521 Olidago virga- aurea 29:586 Olide 20:660 from Salvia potentillifolia 20:660 from Salvia yosgadensis 20:660 Oligazulenes 14:314 Oligo (N-methylpyrrolecarboxamide) antibiotics 5:549-554 isolation and structure of 5:549-554 molecular interactions of 5:575-581 synthesis of 5:575-581 Oligo-2'-5'-adenylates 14:286 synthesis of 14:286 Oligoadenylate synthease 25:718 Oligobiosaminide 22:177 Oligocerus hemorrhages 17:14 Oligodeoxyribonucleotides 4:269-307 automated synthesis 4:280-276 deprotection 4:282,283 hydrogen phosphonate method for synthesis 4:274-276 phosphite method for synthesis 4:271-274 phosphotriester method for synthesis 4:268-271,301-303 purification 4:282,283 synthesis of 4:268,307 synthesis on polymer supports 4:274-276 uses of 4:267,268 Oligoflavanoids 21:497 Oligogalacturonides 25:485,486,487
Oligoheptoses 4:195,196,198 by trichloroacetimidate method 4:203-208 synthesis of 4:203-208 Oligomer 8:377 Oligomeric catechins 27:837 Oligomeric compound 27:778 biological activity of 27:778 Oligomeric DNA 8:373,374,376 Oligomerization 12:189 base-catalyzed 14:271,272,274 of levoglucosenone 14:271,272, 274 of PBG 9:595 Oligonucleotides 4:264-266;25:390 purification of 4:282,283 synthesis of 4:264-316 Oligonychus sp. 28:423 Oligopeptide elicitors 25:396 Oligopeptides 10:639-669;22:23,25; 24:524;27:793 active against HSV and MV 24:521 antibacterial activities of 27:793-804 biological activities of 27:793-804 biomimetic studies of 10:639-669 synthesis of 10:639-669 Oligophagous chrysomelid beetle 26:871 Oligophylidene 13:348,350 from Acronychia oligophylebeia 13:348,350 Oligoribonucleotide synthesis 4:303 by phosphite method 4:303 by H-phosphonate method 4:304,305 by phosphotriester method 4:301-303 protecting group for 2'-hydroxy 4:296 Oligosaccharide moiety 28:611 ofpatagonicoide A 28:611 NOESY correlations of 28:611 Oligosaccharides 4:11,18,29,31-36,39, 42,45,62,69,72,143,203-208,
583
216-218,235,270,278,287-289,291, 315-338;6:397,398,406;22:30 13C-NMR of 4:207,219 IH-NMR of 10:461 biosynthesis of 10:468 chemical synthesis of 14:283-312 FAB-MS of 10:461 from diheptoses 4:204-206 from glycosidases 10:468,470, 471 from glycosyl transferase 10:468-470 of L-glycero-D-manno-heptoses 4:207 synthesis of 4:2-7-212; 8:315-338;10:457-493 Oligosaccharidic moiety 27:524,673 of saponins 27:673 Oligosaccharyltransferase 10:501 Oligosporic actinomycete 14:98 Oligosporic actinomycete strain 21:412 Oligosporon 26:449 Oligostatins 10:517 amylase inhibitor of 10:516 antibacterial activity of 10:516 from Streptomyces myxogenes 10:515 mammalian c~-amylase inhibitors 10:516 microbial c~-amylase 10:516 synthesis of 10:516 Oligostatins C 10:515,516,236 Oligostatins D 10:516 from Streptomyces myxogenes 10:515 Oligostatins E 10:516 from Streptomyces myxogenes 10:515 Oligotide degradation 13:288 3'-exonuclease in 13:288 Olivacine 5:125 Olivacine-type alkaloids 5:88,89 olivacine 5:88,89 Olivacinic acids 4:435,457 as epithienamycin A,B,E and F 4:434 as epithienamycin C and D 4:434
Olive oil 27:697 composition of 27:698,699 effect on nitric oxide metabolism 27:721 effect on reactive oxygeninduced toxicity 27:722 hydrocarbons from 27:700 influence ofcultivar on 27:707 phenols from 27:702,703 prooxidant effects of 27:713 sterols from 27:702 tocopherols from 27:702,703 triterpenes from 27:702 volatile components of 27:700, 701 (+)-Oliveroline 16:511-512 5'-(2H3)-Olivetol 19:191 Olivetol (1,3-dimydorxy-5-pentylbenzene) 9:344;19:186 for 3,5-dimethoxybenzoic acid 9:344 Olivetol dimethyl ether 19:188 (-)-Olivil 5:525 (-)-Olivil-4"-13-D-glucoside 5:525 (-)-Olivil-di-13-D-glucoside 5:525 Olivin 3:173,175 synthesis of 3:191-197 Olivomcin 3:173,175,245 4-en-6[3-ol-one 27:477 -3',5'oMe, 4'[(t-butyldimethylsilyl)oxi] 27:928 Olong tea 27:400 anti-obesity action of 27:400 OLR-1 30:194 as endogenous peptide opioids 30:193 Oltremare process 9:331 Olvanil 30:193,202 analgesic action of 30:193 as anti-inflammatory substances 30:201 as capsaicin congener 30:201 as vanilloid receptor agonists 30:202 for analgesia 30:201 phamacological profile of 30:201
584
role in vasorelaxation 30:201 structures of 30:202 Omeprazol 25:612 O-methyl derivative 11:137 ofkidamycin "glycone" 11:137 O-methyl psychotrins 13:656 1'-O-methyl-ABA 27:334 O-methylancistrocladine 20:408,426, 427,432,436 O-methylbaccharocephol 30:716 structure of 30:716 O-methylfurodysinin 17:9 O-methyltetradehydrotriphyophylline, 7,1-Linked 20:417 O-methyltranferase 25:498,499 Ommatins 26:965,991,992 Ommidinis 26:990 Ommins 26:990 Ommochrome 26:998,1018 Omphalea diandra 11:431 Omphalotins A-D 26:483-486 Omphalotus 29:271 Omphalotus illudens 26:706 Omphalotus olearius 26:483 Onchidal 17:27 Onchidella benneyi 17:27 Onchocerciasis (river blindness) 1:435 treatment of 1:435 Oncogene function inhibitor 15:439-463 from microbial secondary metabolites 15:439-463 screening of 15:463 Oncogene signal inhibitory activity 22:621 Oncogenesis 19:351;25:545 Oncogenic viruses 15:439 Oncolytic effects 25:460 effect of TNF-a 25:460 Oncomelania 7:425 Oncopeltus fasciatus 22:383,393 Oncopeltus spp. 22:392 Oncorhyncolide 21:297 Oncosperma tigillaria 7:176 OncoVax-P 28:545 against prostate cancer 28:545 monophosphoryl lipid A in 28:545
One-carbon homologation 3:238 ofallylic alcohols 3:238 Onekotanogenin 7:278-280 Oneostemon bojerianum 30:139 5-alkylresorcinols from 30:139 Onitin 24:221;26:706 O-NMR spectroscopy 17:557 17 of 1-adamantyl phosphoryl derivatives 9:116-118 ofaryl derivatives 17:557 of chromones 9:113-116 of cumarins 9:113-116 of flavones 9:113-116 of 7-methoxychromanone 9:113 of psoralen 9:114,115 Onnamide 26:1231 Kishi's retrosynthesis of 26:1231 Onnamide A 5:364,365;26:1198, 1231-1234 HETCOSY of 5:367 Onobrychis viciifolia 21:507 a,y-Onoceradienedione 1:658,659 synthesis of 1:658,659 Onocerane triterpenoids 1:658-660 synthesis of 1:658-660 Ononis natrix 15:386 6,8- dihydroxy- 3-unde cyl-3,4dihydroisocoumarin from 15:386 Ononis speciosa 21:591 Onychine 2:443,443 anticandidal activity of 2:443, 443 Onychium auratum 26:706 Onychopetalum amazonicum 2:442 Oochromonas malhamensis 2:293 Oocyte mutation 22:376 Oolong tea 27:401 biological activity of 27:401 Oolong tea 30:80,82 classification of 30:80 Oomycetes 9:202,203;22:460,482; 25:299,303 Oosponal 24:914-917 inhibition of histamine release 24:914-917 Oospora astringens 24:914 oosponol from 24:914-917 Oospores 22:482
585
Open reading frames (ORFs) 25:379 Operon 8:315 protein synthesis 8:315 Operophtera brumata 4:566 Ophiarachna incrassata 7:308,309 Ophiarthrum elegans 7:308,309;15:96 Ophidianoside B,C 7:290,293 Ophidianoside F 7:293,399 from Linckia laevigata 7:290 Ophidiaster ophidianus 7:290;18:460 Ophiobolane 3:93,94 Ophiobolane sesquiterpenes 1:563 Ophiobolin 16:138;26:468 (+)-Ophiobolin C 16:141 synthesis of 16:141 Ophiobolin F 1:563,569 Ophiobolin K 26:468 Ophiobolus vermisporis 28:125 Ophiocarpine 1:190,191 synthesis of 1:190,191 (-)-epi-Ophiocarpine 1:190,191 Ophiocoma dentata 7:308,309;15:96 Ophiocoma echinata 28:721 Ophiocomina nigra 15:100 Ophioderma longicaudum 7:96,309 longicaudoside A and B from 7:94,308 Ophiodiaster ophidianus 15:46 Ophiolepis superba 15:84,96 Ophiomastix annulosa 15:99 Ophiorachna incrassata 15:96 Ophiorine A 1:125,126 Ophiorine B 1:125,126 Ophiorrhizajaponica 1:125 Ophiorrhiza pumila 30:344 anthraquinones from 30:344 Ophiosparte gigas 15:99 Ophioxanthin 28:721 5,6,5 '-6'-tetrahydro-[3,[3carotene-3,4,3 ',4'-tetraol 4,4'disulfate as 28:721 as carotenoid sulfate 28:721 Order aspidochirota 28:594 stichloroside A from 28:594 stichloroside A1 from 28:594 stichloroside A2 from 28:594 stichloroside B from 28:594 stichloroside B1 from 28:594
stichloroside C1 from 28:594 stichloroside C2 from 28:594 Ophistobranch 21:317 Ophiura sarsi 15:98 cholest-5-ene-3 c~,4[3,21-triol3,21-disulphate from 15:98 Ophiuroidea 15:43,94-100,265,307-309 Opiate receptors 21:72;22:24;25:533 Opiates 25:265 as A~ adenosine agonists 25:265 Opioid 22:19;30:193,194,799,799,800 as analgesic 30:799 as anti-nociceptive 30:193 in neurotransmitter system 30:799 pharmacodynamics of 30:799 pharmacokinetics of 30:799 physiochemical properties of 30:800 side effects of 30:194 Opioid agonist 30:813 Opioid analogues 30:800,813 analgesic potencies of 30:800 development of 30:813 permeation of 30:800 structure activity relationship studies (SAR) of 30:800 wOpioid antagonist 30:813 activity of 30:813 Opioid dipeptide 6-antagonist 30:808 physiochemical properties of 30:809 Opioid drug effects 30:203 of ginsenosides 30:203 inhibition by ginseng extracts 30:203 Opioid interaction 30:807 with ~:-receptors 30:807 Opioid peptides 27:801 ;30:799,814 biological activity of 27:801 classes of 30:799,814 from Phyllomedusa amphibians 30:799,814 Opioid receptivity 30:808 of ligands 30:808 g-Opioid receptor 25:530;30:205,801, 802,804,814
586
activity in guinea-pig ileum bioassay 30:802 affinity of 30:802 binding affinities of 30:205 binding sites of 30:814 in MVD assay 30:801 in vitro bioassay of 30:804 interaction with 30:804 pharmacological bioassay of 30:801 radioligand binding assay of 30:801 type of G-protein-linked receptor 25:530 8-Opioid receptor 30:193,799,802,814 as endogenous peptide opioids 30:193 binding sites of 30:814 blocked by naltrindole 30:802 role in analgesia 30:799 Opioid receptor affinities 30:814 of glycopeptides 30:814 determination of 30:814 8-Opioid receptor antagonist 30:204, 803,804 H-Dmt-Tic-Ala-OH (DTA) as 30:804 inhibition of antinociception by 30:204 K-Opioid receptor antagonist 30:204 inhibition of antinociception by 30:204 wOpioid receptor antagonist 30:204 inhibition of antinociception by 30:204 Opioid receptor binding 30:812 of pentapeptides 30:812 Opioid receptor complex 30:194 8-Opioid receptor ligand 30:817 Opioid receptor subtypes 30:800 delta 1 30:800 delta 2 30:800 Opioid receptors 21:95;22:24;30:200 binding of 30:200 ligands for 30:200 Opioid receptors affinity 30:8178in vitro 30:817
pharmacological assay (guineapig ileum) for 30:817 Opioid system 30:799 dynorphins in 30:799 endorphins in 30:799 enkephalins in 30:799 in central nervous system (CNS) 30:799 in peripheral tissues 30:799 ligands of 30:799 physiological functions of 30:799 receptor types (~t,8,K) 799 Opioid tripeptide 8-antagonist 30:808 physiochemical properties of 30:809 Opisthiolopis heterophylla 9:320 Opisthobranchia 17:3 Opium alkaloid 18:45 (+)-Oplopanone 15:247 Oplopanone 15:250 Oppenauer oxidation 13:451 ;20:749 Oppolzer-Battig synthesis 6:45,46 of(+)-A 9(12)capnellene 6:45,46 Oppolzer's acryloyl sultams 10:138 Oppolzer's aldehyde 14:726 (+)-vincamine from 14:726 Oppolzer's chiral acryloyl sultam 19:314 Oppolzer's chiral auxiliary 11:307,308 from (+)-camphorsulfonyl chloride 11:307,308 preparation of 11:307,308 with (E)-3-chloroacryloyl chloride 11:307,308 Opportunistic infections 22:58 Opportunistic Listeria infection 30:773 in immunodeficient mice 30:773 Opportunistic ningi 22:56 Oppositol 6:9,10 from Laurencia subopposita 6:9,10 synthesis of 6:9,10 Opsins 10:150 Optical activity detection 9:462 Optical isomers 27:378 of carvone 27:378
587
Optical purity 6:153 of acetylenic (x-ketols 6:153 of non-acetylenic c~-ketols 6:153 Optical resolution 6:544,552 of (+)-3-oxycyclopentane carboxlic acid 6:559 Optical rotatory dispersion 2:153 Optically active sulfoxides 4:489-491 synthesis of 4:489-491 Opulus iridoids 7:41 O-Quinonic 30:169 formation of 30:169 Oral care products 21:613 Oral glucose tolerance test 27:409 Orbiculamide A 26:1181 Orbiculin D 29:88 activity in NFkB assay system 29:88 activity in NO assay system 29:88 Orbiculin H 29:88 activity in NFkB assay system 29:88 activity in NO assay system 29:88 Orbiculin I 29:88 activity in NFkB assay system 29:88 activity in NO assay system 29:88 Orchis morio 26:1144 Orcinol reagent 19:755 Orconecttes limosus 19:628,668 Oreaster reticulatus 7:304-306;15:61 asterosaponin P~ from 7:297,300 Oreganic acid 24:430 structure of 24:430 Oregonin 17:360;25:543 Orellanine 22:32 Organic synthesis 6:301-303 by 1,3-dithiane 6:301-303 with FAMSO 6:311-323 with MT-sulfone 6:330-340 Organoboranes 8:472,473,478 Organochlorines 25:767 Organocopper reagents 1:626,627 addition to or,D-unsaturated acetals and ketals 1:626,627
Organocuprate reagent 14:509 conjugated addition of 14:509 to enones 14:509 Organoleptic properties 27:379 Organolithium intermediate 21:397 Organolithium reagents 12:411,413 2-amino alcohol by 12:411,413 to (x-alkoxydimethylhydrazones 12:411,413 nucleophilic addition of 12:411, 413 Organometallic addition 4:142 to N, O-protected D-allothreoninal 4:142 Organometallic reactions 4:396,398 in prenylation methods 4:396, 398 Organometallic reagents 4:328-333 nucleophilic additions of 4:328-333 Organometallic tropone derivatives 1:573 addition of Gringard reagent 1:573 addition of organolithium reagents 1:573 Organopalladium reactions 16:367 Organoselenium technology 13:5 Organosilicon compounds 13:473-518 Organosulfar compounds 23:355,455485 chemistry of 23:455-485 from garlic 23:468 in garlic 23:455-485 Oriamide 25:884,885;26:1184;28:682 as cytotoxic peptide 28:682 Oricia renieri 2:121 Oridonin 15:171 from Rabdosia eryocalyx var. laxiflora 15:171 from Rabdosiajaponica 15:172 from Rabdosia longituba 15:173 from Rabdosia macrophylla 15:173 from Rabdosia rosthornii 15:174 from Rabdosia rubescens 15:174 from Rabdosia ternifolio 15:175 Orientin 25:594;29:580 effects on ACE 29:580
588
Origanum compactum 30:269 pyranosyl flavone from 30:269 Origanum genus 27:376 Origanum marjorana 21:599,618; 29:588 Origanum syriacum 27:376 Origanum syriacum var. bevanii 28:427 acaricidal activity of 28:412 Origanum vulgare L. 21:596;22:528; 27:376;29:573,580 for epilepsy 22:528 Orina sp. 25:712 Orinthine 25:66,937 Oriola xanthornus 5:837 hemoglobin components of 5:837 Oripainine 25:533 agonist/antagonist effects 25:533 Orizia latipes 24:119 Ormocarpum kirkii 22:528 for epilepsy 22:528 Ormosanine 14:738,739 biosynthesis of 14:738,739 from L-lysine 14:738,739 Ornithine 22:724 D-Ornithine 27:795 Ornithine decarboxylase 20:513;22:616, 725;25:45,66 by staurosporine 12:393 induction of 12:393 in human bladder carcinoma T24 cells 12:393 role on TPA induced inhibition 25:45 Omithine decarboxylase inhibition 26:924 Ornithine glucuronides 25:90,103 hepatoprotective activity of 25:90,103 L-Ornithine nitro derivative 11:437 condensation of 11:437 Ornithogalum saundersiae 21:636 Ornithopus sativus 18:514,520,523, 529-533 castasterone from 18:503 24-epicastasterone from 18:503 Ornoside 26:318,319,322 Ornosol 26:319,333 Oroidim sp. 21:270
Oroidine 25:783,785;26:819 Orophea enneandra 26:204,255 (-)-epieudesmin from 26:204 (-)-eudesmin from 26:204 (-)-phylligenin from 26:204 Orotidine monophosphate decarboxylase 7:387 Oroxylin A 30:288 structure of 30:288 Oroxylum indicum 29:572,581 Orsellinic acid 9:328,341,346-348, 366,367;11:536 biosynthesis of 11:199 by Penicillium madriti 1l: 198 Ortho-alkoxyacetophenones 14:648 Ortho-alkoxyphenyl ketones 14:647-650 Ortho-alkoxyphenylglyoxalate esters 14:648 Ortho-benzyloxyacetophenone 14:655,656 by Norrish type II photoelimination 14:655,656 from ortho-benzyloxyvalerophenone 14:655,656 Ortho-benzyloxybenzophenone 14:648 Ortho-benzyloxyvalerophenone 14:647 ortho-benzyl ox yac etopheno ne from 14:655,656 Orthoester Claisen rearrangement 1:446,447,598 of divinyl carbinols 3:41 Orthometallation 14:684,686 Ortho-methoxybenzophenone 14:647, 648 photocyclization of 14:647 photoreduction of 14:647 Orthomycins 29:324 against fungi 29:324 against gram-negative bacteria 29:324 against Neisseria meningitides 29:324 against Staphylococcus aureus 29:324 against Streptococcus pyogenes haemolyticus 29:324 against yeasts 29:324 avilamycin A as 29:325
589
avilamycin as 29:324 chemical structure of 29:326 curamycin as 29:324,325 flambamycin as 29:324 from cotton seed 29:327 from soy meal 29:327 from streptomycetes 29:324 genisteins as 29:327 pentalenolactones as 29:328 Orthoptera 22:371,398 Orthoquinodimethanes 3:434 synthesis of 3:434 Orthoquinodimethanes 3:434 synthesis of 3:434 Ortho-quinone 23:165 OrthoscuticeHa ventricosa 17:90,95,101 Orthosiphol A 29:103 activity in TPA bioassay system 29:103 Orthosiphol B 29:103 activity in TPA bioassay system 29:103 Orthosiphon stamineus 29:103 Orthosiphone aristatus 24:274 Orthosphenia 18:754 Orthosphenia mexicana 7:756,758 netzahualcoyon from 7:147 orthosphenic acid from 7:147 triterpenes of 7:147 Orthosphenic acid 7:148,167 from Orthosphenia mexicaca 7:147 X-ray analysis of 7:147 Orthosphenin 18:755;23:678 Oxadiazinone 23:257 Oxazolidine aldehyde 23:188 14-Oxotricosanoic acid 23:823 Oxycurcumenol 23:836 P 8/1-OG 23:84 Orygyia pseudotsugata 20:124 Oryza oryzacystatin-I 29:593 effects on papain 29:593 effects on cathepsin H 29:593 Oryza sativa 1:529,522;20:247;23:342; 25:377 ;29:599;605 Oryzias latipes 21:365 Oscillariolide 19:567 isolation of 19:567
NOESY data of 19:567 relative stereochemistry 19:567 Oscillatoria sp. 19:567;26:352 Oscillatoria agardhii 26:352,365 Oscillatoria cf. chalybea 26:362,373, 379 Oscillatoria genera 27:879 Oscillatoria latevirens 26:364 Oscillatoria nigroviridis 18:294;19:586
Oscillatoria perornata f. attenuata 26:373,374,379
Oscillatoria spongeliae 21:283 Oscillatoxin D 18:269-309 synthesis of 18:269-309 Oscillaxanthin 20:592 Oscillol 20:592 (~)-Oscine 22:731 Oscsllatoria agardtii 25:799 Osladin 15:27;27:16,31,32 structure of 27:32 Osmanthus 26:327 Osmium (III) chloride 12:162 Osmium tetraoxide 4:169,178 hydroxylation with 4:508,509 in cis-bishydroxylation 4:160, 163 selectivity of 4:160-162,172,180 Osmorhiza longistylis DC 27:16 trans-anethole from 27:16 Osmylation 1:141,413,441;4:160,162, 175-185;6:182;13:400,401 ;16:323, 324,326,329,332;19:226-275 anti-stereoselective 4:161,162, 167,170,171,178 in synthesis of eight-carbon sugars 4:163-172 in synthesis of eleven-carbon sugars 4:188 in synthesis of nine-carbon sugars 4:180-182 in synthesis of seven-carbon sugars 4:175-179 in synthesis of ten-carbon sugars 4:192-185 Kishi's rules 1:413,414 of allylic ethers 1:413,414 of chiral allylic alcohols 4:160 of bis-allylically substituted
590 cyclopentenes 19:355 syn-stereoselective 19:355 Osteoarthritic cartilage 30:318 Osteoarthritis 30:192 use of inflammatory drugs (NSAIDs) 30:192 use of prostaglandin inhibitors 30:192 Osteoarthritis pathophysiology 30:318 interleukin- 113 role in 30:318 Osteomalacia 9:509 Osteoporotic drug 25:711 Ostertagia circumcinta 26:453,490 Ostertagia ostertagi 26:484 Osthol 20:497 from Limonia acidissima 20:497 Ostodes 25:242 Ostreopsis lentcularis 26:69 Ostrina furnacolis 23:66 Ostrinia nubilalis 26:186 Ostryajaponica 17:369 Ostrya sp. 17:369 Otanthus maritmus 21:378,381;24:687 piperide trienamide from 21:378 piperidine from 21:378 piperovatine from 21:378 12-O-tetradecanoylphorbol- 13-acetate 20:513 Otivarin 18:193;26:441,442 Otoba parvifolia 26:186 Otonecine 1:242;8:211 synthesis of 1:242;8:211 Otophylloside A 22:518,538 Otophylloside B 22:518,538 Otoseine 26:875 Ottonia anisum 24:704,710,711 Ottonia corcovadensis 24:693,694, 704,711 Ottonia vahlii 21:378 Ouabagenin 3-O-L-rhamnoside 25:535 Ouabain receptor 26:216 Ouchterlony plate technique 7:115 Oudemansiella mucida 3:257;22:249 Oudemansin A 3:257-259 synthesis of 3:257-259 Oudemansin B 3:257-259 synthesis of 3:257-259 Ouregidione 20:481 Ourouparia gambir 1:25
Ourouparine 1:125,126,137,138 synthesis of 1:137,138 Oval glucose tolerance test 27:409 Ovalicin 22:261 ;26:459 Ovaliflavanone 4:378 8-prenylfavanone in 4:378 Ovaliflavanone B 4:378 allylation of 4:21 and 6,8-diprenylflavanone in 4:378 Ovarian cancer 24:933 Ovarian cancer treatment 24:933 taxol for 24:933 Ovarian tumor 30:5,27 clinical development for 30:5 chemotherapeutic agent for 30:5 effect of pironetin derivatives in 30:27 inhibitors of tubulin 30:27 OVCAR-3 cells 21:175 Overhauser effect 11:293,15:204-206 in saponins 15:204-206 Overman synthesis 13:487,488 of(+)-elaeokanine B 13:487, 488 of (+)-streptazoline 13:514,515 (+)-Ovigerine 30:565,590,594 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 as platelet aggregation inhibitor 30:594 cytotoxic effect of 30:589 Ovihernangerine 30:566,584 by HREIMS of 30:584 ElMS of 30:584 IR spectrum of 30:584 molecular formula of 30:584 UV spectrum of 30:584 (+)-Ovihemangerine 30:590 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:589 Oviparous insects 22:376 Oviposition attractant pheromone 3:157
591 Oviposition inhibitor 28:403 dibenzyltrisulfide as 28:403 Oviviviparous insects 22:377 6-Ovolhiol CR1 25:813 Ovoperoxidase 25:813 Ovothiol A-C 25:813 4-Ovothiol AR1 25:813 5-Ovothiol RB1 25:813 Ovothiols 28:716 from marine invertebrate eggs 28:716 of mercaptohistidines 28:716 Ovoverdin 6:161 Oxa concept 9:515 cis-5-Oxa- 1-indanones 6:558 cis-selective formation of 6:558 22-Oxa- 1c~,25-dihydroxy-vitamin D3 9:518,519 20-Oxa- 1c~,25-dihydroxy-vitamin D3 9:518 22-Oxa- 1ct-hydroxy-vitamin D3 9:518,519 Oxa- 1c~-hydroxy-vitamin D3 9:5182025-Oxa-25-phospa-vitamin D3 9:520, 521 synthesis of 9:521 25-Oxa-25-phospha-vitamin D3 9:509-528 total synthesis 9:509-528 1-Oxabenz [a] anthracene 11:136,137 Oxabicycles 10:214 synthesis of 10:214 (-)-(1S,4S)-7-Oxabicyclo [2.2.1] hept-5en-2-one 12:340 7-Oxabicyclo [2.2.1 ] hept-5-en-2-ylderivatives 11:462 7-Oxabicyclo [2.2.1 ] heptan-2-ones 14:180 Oxabicyclo [3.2.1] octane 12:28,29 Oxabicyclo [4.3.1 ] decane 10:214 synthesis of 10:214 7-Oxabicyclo [4.3.0] nonane 12:28 (+)-(1R,4R)-7-Oxabicyclo[2.2.1 ] hept-5en-2-one 12:340 Oxacillin 9:413 A3&Oxahydrindene 12:18,19 Oxahydrindene subunit, of avermectins 12:9-11
Barrett's approaches for 12:9-11 Crimmins synthesis of 12:11,12 Danishefsky synthesis of 12:12, 13 Fraser-Reid synthesis of 12:13, 14 Hanessian synthesis of 12:14,15 Hirama synthesis of 12:15,16 Ireland approach for 12:15,16 Julia synthesis of 12:19,20 Jung synthesis of 12:19,20 Kozikowski approach 12:20-22 Ley synthesis of 12:25,26 Smith synthesis of 12:25,26 Vang synthesis of 12:26,27 White synthesis of 12:27,28 Williams approach for 12:28-30 9-Oxaisotwist-8-en-2-one 8:166-168 synthesis of 8:166-168 Oxalacetic acid 30:433,435 as pyruvate equivalent 30:433 reaction of 30:433 7-Oxalactone 19:252 regioselective preparation of 19:252 Oxalic acid 7:180;28:386 in honey 28:386 in mangrove plants 7:180 Oxaloacetic transminase 25:935 Oxalyl chloride 9:526 Oxamicetin 4:234,241 Oxandra espinata 26:807 7-Oxanorbornenyl derivatives 11:462-464 homologation with 11:462-464 Oxaphosphetane 6:545 Oxaquinolizidine 24:578,604,605 13C spectra of 24:604,605 Bis- 1-Oxaquinolizidines macrocyclic alkaloids 21:267 Oxaspiropentane 10:616,617 Oxaspiropentane rearrangement 10:616-618 1,2,3-Oxathiazolidin-2-ones 14:518,519 Oxatricyclo [4.4.2.015] structure 6:538,539 Oxatropane 6:433,434 solenopsin A from 6:433,434
592 Oxaunomycin 14:493,495 synthesis of 14:493,495 [ 1,2]-Oxaza ring formation 6:472 by Meisenheimer rearrangement 6:472 1,2-Oxazine 6:449 monomorine I from 6:449 Oxazine 8:291 Oxazine alkaloid 25:542 Oxazoles 22:9 Oxazolidene-2,4-dione 13:483 Oxazolidine-2-ones 12:446 Oxazolidine-2-thiones (goitrogens) 26:1074 Oxazolidines 1:337 cycloreversion of 1:337 2-Oxazolidinone 12:411,415 3-acetyl-2-oxazolone from 12:411,415 acyclic amino alcohol from 12:428-430 acyclic N-boc amino alcohols from 12:428-430 from 1,35-tris (2-hydroxyethyl) cyanuric acid 12:411,415 N-protection of 12:428-430 2-oxazolone from 12:411,415 ring opening of 12:428-430 with di-tert-butyl dicarbonate [BOC)20] 12:428-430 debenzylation of 14:569 from N-benzoylcarbamate 14:569 pyrrolidine derivative from 14:569 Oxazolidinone auxiliaries 18:161 2-Oxazolidinone ring 12:428-430 4-methoxy group on 12:428-430 substitution of 12:428-430 2-Oxazolidone derivatives 12:166 synthesis of 12:166 Oxazoline 10:474-477;25:881 as chiral auxiliary 4:327,332,333 of 2-acetamido-2-deoxy-Dglucose 6:399 in the synthesis of Li substances 10:473 in the synthesis lacto-N-biose 10:473
A-2-Oxazoline 4:140,141 from D-threonine 4:140,141 with furfurylithium 4:140,141 Oxazoline derivative 6:399 Oxazoline method 6:393 Oxazoline rings 4:86 synthesis of 4:86 Oxazolo [4,3-a] decahydroisoquinolines 12:464 2-Oxazolone 12:411,415 from 2-oxazolidione 12:411,415 preparation of 12:411,415 N-acetyl derivative 12:411,415 Oxepahyperforin 30:613 structure of 30:613 Oxepan-4-ones 10:219 Oxepane 10:202,205-207 synthesis of 10:202,205-207, 209-212,214,215,224-226 bis-Oxepane 10:205 cis-Oxepane 10:211,212 trans-Oxepane 10:211,212 synthesis of 10:211,212 Oxepane diterpenes 24:806 Oxepanols 10:230 synthesis of 10:230 3-Oxepanols 10:231 synthesis of 10:231 Oxepanone 10:205,209 3-Oxepanones 10:209,210 Oxepins 10:236 synthesis of 10:236 Oxetane 22:219 Oxetanocin 10:585-627 synthesis of 10:585-627 Oxetanocin A 10:619,620 antiviral activity of 10:619,620 by N-glycosidation 10:595-607 from acyclic nucleoside derivative 10:588,592 from Bacillus megaterium 10:585 from furanosyl nucleoside 10:592-595 total synthesis of 10:587-608 transformation of 10:586,587 with 1-O-acyl-oxetanose 10:597-604 with oxetanosyl derivative
593
10:595-607 with oxetanosyl halide 10:604-607 Oxetanocin G 10:586,587 antiviral activity of 10:619,620 Oxetanocin H 10:586,587 Oxetanocin X 586,587 Oxetanosin A 19:511 Oxetanosyl halide 10:604-607 synthesis of 10:604-607 P-450-Oxidase 22:9 Oxidation 24:13,16,17,27,28,32,33,36, 37,80,82,94-96,104,124,178,179, 185;27:749,774 aerial 16:66 by ninhydrin 16:83 by Sharpless procedure 8:23 enantioselective 13:54 enzymatic 13:58 in vitro 6:138 in vivo 6:138 Lemieux-Johnson, 4:592,593 nitro to keto 1:417,418 of (+)-catechin 27:774 of cytochrome P450 enzymes 27:348 of terminal acetylene 27:348 of xenobiotics 27:749 of vincristine 27:778 of (-)-bomeol 16:124 of (+)- 5-methoxylaudanosine 16:506 of (+)-camphor 16:149,153 of (+)-laudanosine 16:506 of 1,1'-methylene bis (3,7diisopropylazulene) 14:340,341 of 1,3 dimethylazulene 14:336, 337 of 1,5-diisopropylazulene 14:337,338 of 1-isopropylazulene 14:336 of 2-ethyl-5-pentylpyrrolidine 6:444 of 2-furycarbinol 19:473 of 3,3'-methylene bis (guaiazulene) 14:343-345 of 4,6,8-trimethylazulene 14:341,342 of alcohol 16:40,350
of alcohols to ketones 4:331 of aldehyde 16:294;19:210 of alkene 16:459 of allylic alcohol 16:296 of amides 1:10 of aromatic compounds 6:509 of azulenic hydrocarbons 14:313-354 ofbenzylic alcohol 19:225 of bromonaphthol 16:48 of cholesterol 17:207 of conjugated dienes 16:420 of dimethyl 2-amino- 1,3azulenedicarboxylate 14:339 of di-substituted azulenes 14:336,337 of ellipticine 6:509 of enol acetate 19:207 of enol ether 16:85 ofenolate 16:474 of FAMSO 6:326 of formaldehyde dimethyldithioacetal 6:326 of friedelin 7:160,161 of genipin 16:313 ofguaiazulene 14:313-354 of hemiacetal 1:453,454 of hydrazide 16:473 of lactol 19:473 of oleanane triterpenoids 7:159-161 of olefin 10:111 ofolefins to ketones 4:333 of phenolate 19:233 of phenylsulfide 16:296 ofphosphite linkage 4:280 ofphosphonate linkage 4:280 ofphosphonium ylides 4:558, 559 of secondary hydroxyl group 19:489 of sulfide to sulfone 1:454,456 of taraxerone 7:160,161 of tertiary allylic alcohol 19:262 of tetrahydroisoquinolinols 16:519 of tetra-substituted azulenes 14:343-345 of tri-substituted azulenes
594
14:339-342 of unactivated carbons 2:90-103 of cc,[3-unsaturated ketones 4:100 Pd (II) catalysed 4:100 photochemical 1:159 regioselective 19:262 Swern 1:453,454 using Kelly procedure 10:111 with AczO-AcOH 8:160,162 with Attenburrow-MnO4 8:119 with benzeneselenic anhydride 4:40,41,52 with ceric ammonium nitrate 4:331,332;6:472 with ceric sulphate 1:159 with Collin's reagent 1:360,363, 367 with DDQ 8:169;19:473 with HzOz-aq. NaOH 8:163 with HgO/I2 1:454,456 with iodine 1:126,138 with Jones reagent 19:136 with KMnO4-NaOtBu 1:417 with manganic acetate 4:72 with mCPBA 2:90-103;19:71 with MnO2 8:198;16:294 with N(n-Prop)4 RuO4 8:150-152 with o-chloranil 1:131,132,135, 137 with osmium tetraoxide 10:111 with OsO4 8:23;16:292 with oxone (KHSOs) 1:454,456 with palladium 1:131,133 with Pb (OAc)4 8:165 with PCC 19:62,473,541 with PDC 19:145,265 with Ph I (OCOCF3)2 4:73 with PPC 1:440 with pyridinium chlorochromate (PCC) 8:22,23,163;11:401 with pyridinium dichromate 4:331 with RuO4 1:404,405;8:150-152 with RuO4-NalO4 8:162 with SeO2/t-BuOOH 8:2,3 with silver carbonate 1:453,454 with silver oxide 11:86 with sodium chlorite 16:83 with sodium metaperiodate
4:50;19:354 with sodium periodate 16:293 with Swern oxidant 6:119,120 with tetrapropylammonium metaperiodate 1:379,380 with thallium acetate 4:72 with thallium nitrate 4:338; 8:166,167,169 [3-Oxidation 21:458;25:166 Oxidation-Wittig homologation 13:612, 613 stereospecific 9:255,256 Oxidative burst 27:65,66 Oxidative cleavage 30:8 ofp-methoxybenzyl (PMB) ether 30:8 Oxidative conversion 19:484 Oxidative coupling reaction 8:160 olefin 8:160 of phenol 8:160 Oxidative cyclization 9:533 of davanones 9:533 Oxidative decarboxylation 1:536 of cx-keto acids 1:536 Oxidative degradation 13:303-306 of fatty acids 13:303-306 of ilimaquinone 9:31 Oxidative demethylation 5:769 Oxidative DNA damage 25:66 Oxidative elimination 3:260 of arylselenide 3:260 Oxidative halogenation 27:750 and electron transfer 27:750 Oxidative hydroboration 12:318,322, 344;14:460,461 Oxidative hydrolysis 30:438 formation of 30:438 ofdithioacetal moiety 30:438 of KDO derivative 30:438 Oxidative Nefconditions 19:73 Oxidative olefination 4:448 Oxidative phenolic coupling 20:291-293 in biosynthesis of 20:291-293 natural products by 20:263-315 Oxidative rearrangement 16:650 Oxidative transformations 7:159-168 Oxidative-degradation system 7:105 Oxidative-hydralase system 7:105
595
Oxidising action 2:3 of NO in CI (NO) mass spectra 2:3 Oxidizing agents 19:120 Oxidizing enzymes 6:520 in Strychnos dinklagei 6:520 Oxido ketones 2:169 CD of 2:169 octant rule for 2:168 12,13S-Oxido-9Z, 11-octadecadienoic acid 9:577 3,19R-Oxido-coronaridine 5:127 22,25-Oxidoholothurinogenin 7:268 Oxidopyraziniums 1:341,342 Oxidopyridinium ions 1:340 1,3-dipolar cycloadditions of 1:340 Oxidopyrylium-alkene cycloaddition 12:269 Oxido-reductase 17:480,481 C-Oxidoreductase 7:105 6R-3,6-Oxido-voacangine-N4-oxide 5:127 Oxime sulfonate 6:433,43 solenopsin B from 6:433,43 Oxinastatin-4 25:721 Oxindole alkaloids 15:485-487;25:3,4, 25,26,27,33 Oxindoles 9:196,197 Oxindole-type alkaloids 5:107 conopharyngine oxindole 5:107 7S-isovoacristine 5:107 Oxinellamides 25:757 Oxirane opening 1:560,561 influence of (x-OH 1:560,561 reaction with lithiated nucleophile 1:157 regiospecifity of 1:560,561 with dilithioacetate 1:558,560, 561 Oxirane ring opening 30:463 Oxirans 12:411,413 2-amino alcohol by 12:411,413 ring opening of 12:411,413 with nitrogen nucleophiles 12:465 Oxitropium 22:738 Oxo reaction 3:223,4:255
Oxo-(E)-2-decenoic acid 19:123 synthesis of 19:123 queen substance 19:123 12-Oxo- 11-nor-drim-8-en- 14-oic acid 29:87 6-Oxo- 12-methylroyleanone- 18-oic acid 20:661 from Salvia divaricata 20:661 7-Oxo- 13-epi-pimara-8,15-diene- 18-oic acid 20:690 from Salvia heldrichiana 20:690 6-Oxo-16-epi-silicine 5:126 cis-3-Oxo- 1-hydroxyindolizidine s 12:279 trans-3-Oxo- 1-hydroxyindolizidines 12:279 Ent-4-Oxo-2,3 3-dihydrosolamin 18:197-199 synthesis of 18:197-199 4-Oxo-2,33-dihydrosolamin 18:199 2-Oxo-2,3-dihydrotryptamine 26:117 3'-Oxo-20'-deoxyleurosidine 14:812 from 20'-deoxyleurosidine 14:812 25-Oxo-25-phosphacolecalciferol 9:522 8-Oxo-2'-deoxyguanosine (8-oxo-dG) 8:376,378,388,392 8-Oxo-2c~,9-dihydroxy-trans, transgermacra- 1( 10),4(5)-dien-trans-6,12olide 27:563 9-Oxo-3-fluorenelacetate 11:124 from diethyl phthalate 11:124 bis-(2-Oxo-3-oxazolidinyl) phosphinic chloride 12:46,47 19-Oxo-3 [3,20S-dihydroxydammar-24ene 18:650 3-Oxo-4,5-oxidosteroids 12:236 photoisomerization of 12:236 6-Oxo-4,8-dimethylnonanoic acid 15:228 1-Oxo-4'-Demethoxy-3',4'-methylenedioxyrocaglaol 26:203 3-Oxo-4-methyladipic acid 8:306 2-Oxo-4-phenyl-3-butenoate 20:849, 20:851-853 2-Oxo-7,7-dimethylbicyclo [2.2.1 ] heptane-1-carboxylic acid (ketopinic acid) 12:416,417
596
1-Oxo-7c~-hydroxysitosterol 20:707 from Salvia glutinosa 20:707 3-Oxo-8 ot-hydroxy- 10e~H-eremo-phila1,7(11)-dien-12,8[3-olide 29:87 activity in NO assay system 29:87 2-Oxo- 8 [3-methacryloyloxy- 10othydroxy-guaia-3,11 ( 13)-dien-6c~, 12olide 29:90 activity in NFkB assay system 29:90 2-Oxo-8 [3-methacryloyloxy- 10[3hydroxy-guaia-3,11 ( 13)-dien-6ot, 12olide 29:90 activity in NFkB assay system 29:90 2-Oxo-8 [3-methacryloyloxy-guaia1( 10),3,11 (13)-trien-6c~, 12-olide 29:90 activity in NFkB assay system 29:90 13-Oxo-9,11-octadecadienoic acid 27:73 generation of 27:73 13-Oxo-9-hydroxy- 10-octadecenoic acid 27:73 generation of 27:73 1-Oxo-abieta-8,11,13-triene- 18-oic acid 20:667 from Salvia tomentosa 20:667 3-Oxoadipic acid 8:295-297 1-Oxoaethlopinone 20:680 from Salvia candidissima 20:680 2-Oxoaldonates 20:857 13-Oxoambliofuran 1:671 synthesis of 1:671 [3-Oxoamides 14:650,651 N-alkyl-4-hydroxy-2-pyrrolidinones from 14:650,651 photochemistry of 14:650,651 3'-Oxoanhydrovinblastine 14:812-814 from anhydrovinblastine 14:812-814 from anhydrovinblastine N-oxide 14:812-814 Oxoaporphine alkaloids 2:434 in candidiasis 2:434
Oxoaporphines 20:483 ofMilius banacea 20:483 of Xylopia acthiopica 20:483 synthesis of 3:441 Oxoavicine 3:446,447 synthesis of 3:446,447 6-Oxo-B/C-trans-morphinan 12:465 3-Oxobicyclo [4.3.0.] nonan-2-one-type skeleton 20:68 4-Oxobutanoic acid amides 21:385 4-Oxobutanoic ethyl ester 21:385 N-(4-Oxobutanoyl) piperidine 21:385 4-Oxobutryric acid 9:548 N-(3-Oxobutyl) cytisine 15:525 from Echinosophora koreensis 15:525 6-Oxocampestanol 25:415,420 cis-Oxocan-3-one 10:235 Oxocan-4-ones 10:219 from titanium tetrachloride mediated cyclization 10:219 Oxocane 10:213,214,219,220,232,236 synthesis of 10:213,214,219,220, 232,236 cis-Oxocane (pseudo-gloeosporone) 10:217,218 synthesis of 10:217,218 3-Oxocanones 10:235 by [3,3]-sigmatropy 10:235 synthesis of 10:235 Oxocarbenium ion 16:94,95,108 formation of 16:94 2-Oxo-carboxylates 20:840-842 (R)-2-hydroxycarboxylates to 20:840-842 reduction of 20:840-842 6-Oxocativic acid 25:250 Oxocene 10:204 oxidation of 10:204 synthesis of 10:203,204,211, 218,224,225 unsaturated 10:231 Oxocenones 10:217 synthesis from 8-1actones 10:217 (+)-8-Oxocephalotaxine 18:319 3-Oxo-cholesta-4,23-dien-22-01 9:84,85,87 Oxocompostelline 3:428 synthesis of 3:428
597 3-Oxo-conoduramine 5:129 3-Oxo-conopharyngine 5:128;9:174 3-Oxo-coronaridine 5:124 5-Oxo-coronaridine 5:127 6-Oxo-coronaridine 5:127 3-Oxocoronaridine 9:171 3-Oxo-coronaridine hydroxyindolenine 5:127 1-Oxo-costic acid 6:16 by Collins oxdation 6:16 synthesis of 6:16 Oxocularine 3:428 synthesis of 3:428 6-Oxo-cycloartan-3,16 25:200 3-Oxocyclopentane carboxylic acid 6:558,559 5-Oxo-cylindrocarpidine 5:128 24-(E)-3-Oxo-dammara-20,24-dien-26al 30:657 ~H-NMR spectrum of 30:657 IR spectrum of 30:657 2-Oxo-D-gluconate 20:857 Oxodienoic acids 9:563 7-Oxo-dihydrokarounidiol 22:124 13-Oxo-dodeca-5Z,8Z,10E-trienoic acid 9:534 6-Oxo-drimenol-3a-isovalerate isofraxidin ether 27:593 17-Oxoellipticine 6:508-510,512 biosynthesis of 6:521 by regiospecific oxidation 6:508 from ellipticine 6:508 from N-~-oxy-17-oxoellipticine 6:515 17-hydroxyellipticine from 6:515 reduction of 6:509,515 spectral data of 6:509 synthesis of 6:509,510,511 3-Oxo-erythrinans 3:469 by [2+3] cycloaddition 3:469 by non-oxidative coupling 3:468,469 6-Oxoferruginol 20:670 from Salvia napifolia 20:670 Oxoferruginol 20:673 from Salvia acetobulosa 20:673 from Salvia multicaulis 20:673
1-Oxoferruginol 20:673 from Salvia acetobulosa 20:673 from Salvia multicaulis 20:673 from Salvia napifolia 20:670 3-Oxoferruginol 20:673 from Salvia acetobulosa 20:673 from Salvia multicaulis 20:673 7-Oxoferruginol- 18-al 20:669 A3(4)-15-OxO-flabellin 27:579 4-Oxo-flavonoids 28:263 structure of 28:263 (+)-Oxogambirtannine 13:489,490 21-Oxogelsemine 15:478 from Gelsemium sempervirens 15:479 19-Oxogelsenicine 15:481,482 from Gelsemium elegans 15:482 21-Oxogelsevirine 15:478,479 from Gelsemium rankinii 15:479 19-Oxo-gelsevirine 15:481 from Gelsemium elegans 15:481 4-Oxogeranyl acetate 9:530 1-Oxo-gibberellin 8:121,122 synthesis of 8:121,122 Oxoglaucine 2:436,441 ;20:483 2-Oxoglutarate 22:729 [3-Oxoglutarate derivative 11:130,131 (+)-semivioxanthin from 11:130, 131 7-Oxohernagine 30:565,590,595 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 as platelet aggregation inhibitor 30:594 cytotoxic effect of 30:589 3-Oxo-heyneanine 5:127 (+)- 1-Oxoindolizidine 12:279 hydrogenation of 12:279 synthesis of 12:279 with (+)-3-bromocamphor-8sulfonic acid 12:280 with (3)-3-bromocamphor-8sulfonic acid 12:280 (-)-(S)- 1-Oxoindolizidine 12:279 configuration of 12:279
598 7-Oxoindolizidine 12:286 7-ethyl-7-hydroxyindolizidine 12:286 7-hydroxy-7-phenylindolizidine from 12:286 reduction of 12:286,287 synthesis of 12:286,287 (S)-l-Oxoindolizidine 12:314 (+)-2-Oxoindolizine 12:283,284 reduction of 12:283,284 synthesis of 12:283,284 2-Oxo-isocaproate 26:968 7-Oxoisomultiflorenol 22:124 6-Oxoisophorone 20:573 Oxoisophorone 20:607 4-Oxoisophorone 27:337 6-Oxo-isophorone 6:144,145 14-Oxoisopimaric acid 20:689 from Salvia candidissima 20:689 from Salvia wiedemanni 20:688 23-Oxoisopristimedrin III 7:147-149 23-Oxo-isopristimerin 5:744,745,748 3-Oxo-isovoacangine 5:125 15-Oxolabda-8(17),11Z, 13E-trien- 19oic acid 29:101 activity in EBV bioassay system 29:101 activity in skin-1 bioassay system 29:101 15-nor- 14-Oxolabda-8(17), 12E-dien- 19oic acid 29:101 activity in EBV bioassay system 29:101 15-Oxolabda-8(17), 13Z-dien- 19-oic acid 29:101 activity in EBV bioassay system 29:101 3'-Oxoleurosidine 14:813 from leurosidine 14:813 2 l'-Oxoleurosine 14:813 from leurosine 14:813,814 3'-Oxoleurosine 14:813 from leurosine 14:813 2-Oxo-L-gulonate 20:858 3-Oxo-malabarica- 14(26), 17E,21-triene 27:591 11-Oxo-manoyl oxide 25:252,256 6-Oxo-methuenine 5:126
5-Oxomilbemycin D 12:20 conversion to milbemycin D 12:20 (+)-3-Oxo-minovincine 5:125 3-Oxominovine 19:92 11-Oxomogroside V 15:24;27:14,26,27 structure of 27:27 13-Oxomyricanol 17:371 4-Oxo-mytiloxanthin 6:152 from Asterias rubens 6:151 3'-Oxo-Na-demethyl-Na formylleurosine from 14:818,819 3'-Oxo-Na-demethyl-Na-formylleurosine
14:818,819 from 3'-oxoleurosine 14:818,819 Oxonane 10:209 Oxonantenine 2:436 Oxone (KHSOs) 1:454,456 oxidation of sulfide to sulfone 1:454,456 4-Oxonerol 9:530 Oxonitidine 3:446-447 synthesis of 3:446-447 13-Oxo-octadecadienoates 9:563 3-Oxo-oxepanes 10:209 3-Oxopachysiphine 9:190 3-Oxopentanoic acid 12:172 (4-Oxopentyl) D-glycoside 10:420 photolysis of 10:420 Oxoperexinone 5:773 conversion to dehydrooxoperexinone 5:773 synthesis of 5:772,773 Oxophoebine 20:483 Oxopropyl glycosides 30:45523-( 1-Oxopropyl) pyrrol-2 (5 H)-one 13:111-113 3-(2'-Oxoprop yl-)- 19-epi-he yne anine 5:128 3-(2-Oxopropyl-)-coronaridine 5:126 21-Oxopseudotabersonine 19:108 7-Oxoquinocarcinol methyl ester 19:296 7-Oxoquinonemethide dispermoquinone 30:672 structure of 30:672 24-Oxo-reissantiadiol 5:744,748,750 3-Oxo-reissantiadiol 5:744,748,750 7-Oxoroylcanone 20:712
599 7-Oxoroyleanone 26:402 6-Oxoroyleanone- 18-oic acid 20:661 from Salvia divaricata 20:661 3-Oxosalvipisone 20:680 from Salvia candidissima 20:680 1-Oxosalvipisone 20:688 from Salvia candidissima 20:680 Oxosanguinarine 27:173 structure of 27:173 6-Oxo-silicine 5:126 3-Oxosilphenene 3:6,62 (-)-5-Oxosilphiperfol-6-ene 13:11-13 5-Oxosilphiperfol-6-ene 3:6,63 20-Oxosteroid 19:467 3-Oxotabersonine 9:190;5:127;19:103 7-Oxotetradehydronoraporphine 16:504 5-Oxotetrahydrofuran-3-acetic acid 27:522 3-Oxotirucalla-7,24-diene-21-oic acid (triterpene) 29:575 effects on HIV- 1 protease 29:575 1-Oxotrienylpyrrol-2(5/-/)-ones 13:121124 Oxotryptamine 26:118 3'-Oxovinblastine 14:813 from vinblastine 14:813 3-Oxovincadifformine 9:190;19:9394,99,102-103 formation of 19:102 from Amsonia elliptica 19:93 synthesis of 19:92 19-Oxo-voacangine 5:128 3-Oxo-voacangine 5:128 11-Oxo-c~-amyrin 20:707 1-Oxo-c~-longipinane 27:587 1-Oxo-c~-longipinene (vulgarone B) 9:534 11-Oxo-~-amyrin 20:707 N-b-Oxy- 17-oxoellipticine 6:513 from Nb-oxyellipticine 6:515 from Strychnos dinklagei 6:515 17-oxoellipticine from 6:515 reduction of 6:515 spectral data of 6:515,519 17-Oxy-20-desethyl-A2~ ~)-didehydroeburnamonine 14:729
from desethyleburnamonine enamine 14:729 Oxyacanthine 21:57 Oxyallyl zwitterion 14:587 Oxyaminations 12:411,413 2-amino alcohol by 12:411,413 of alkenes 12:411,413 Oxyayanin A 5:679 Oxyberberine 6:470 magallanesine from 6:470 Oxybisberberine 1:191 Oxychelerythrine 14:773-775 from berberine 14:773-775 reduction of 14:773-775 synthesis of 14:773-775 through enamide-aldehyde cyclization 14:774,775 to chelerythrine 14:774,775 Oxychelirubine 14:777,778 chelirubine from 14:777,778 macarpine from 14:781-783 Oxychlororaphine 26:365 Oxy-Cope rearrangnement 3:96;6:28, 29,36,538-540;7:216;8:179,234,246, 249;10:61,416;11:43,45-49,627; 18:17 anion assisted 16:459 anionic 4:591;16:127,127;19:6 in the synthesis of macrocycles 8:245 of tertiary alkoxide 16:127 suprafacial 16:12 13-Oxycoptisine 6:492 from protopine alkaloids 6:492 in furodysinin synthesis 6:28,29 in furodysin synthesis 6:28,29 in poitediol synthesis 6:36 Oxycoryina fascicularis 25:251,727 Oxycyclopropanes 8:34,35 synthesis of 8:34,35 Oxydifficidin 5:606,607 Oxydihydromorusin 28:230 biological activity of 28:230 N-b-Oxyellipticine 6:507,519 N-b-oxy- 17-oxoellipticine from 6:516 spectral data of 6:516 Oxyferryl porphyrin rt 27:738
600
Oxy- functionalization 27:749 of aromatic amines 27:749 of phenols 27:749 Oxygen compounds 29:317 lysolipins I as 29:317 naphtocyclinone as 29:319 naphtomevalin as 29:319 of simocyclinon D8 29:319 [3-X-4-Oxygenase 21:304 Oxygenases 22:4 6-4tx-Oxygenated aryldecahydroisoquinolines 12:457,458 stereospecific synthesis of 12:457,458 AS-7-Oxygenated brassinosteroids 18:515-520 synthesis of 18:515-520 Oxygenated cembranes 8:15 Oxygenated homophthalates 11:120 polysubsituted anthracenes from 11:120 Oxygenated monoterpenoids 27:373 Oxygenated pyrazines 5:246,247,251 Oxygenated trichodiene 13:524 [3-Oxygenated-t-amino acids 12:476-489 stereoselective synthesis of 12:476-489 Oxygen-containing heterocycles 10:220,221 by cyclization of mixed acetals 10:220,221 from Lewis acid catalyzed reaction 10:220,221 Oxyhemoglobin 26:986 Oxymercuration 10:67,185,324 Oxymercuration cyclization 1:423,425 Oxymercuration-demercuration procedure 14:538,539 Oxynitidine 14:775,776 nitidine from 14:775,776 Oxysanguilutine 14:777,778 sanguilutine from 14:777,778 Oxysporidinone 21:218 Oxystigma buecholtzii 25:165 Oxystiols 5:405-410 cytotoxic activity of 5:406
Oxyterihanine 14:776,777 from protoberberine 14:776,777 synthesis of 14:775-777 Oxytocin 2:30 reduction during FAB MS 2:30 Oxytrogenin 25:96 Oxytropis genera 27:523 Oxytropis sericea 27:516 Oxytropis sp. 27:253,444,514 Ozonization 1:264,265 ;26:355 ofolefin 1:439 of (+)-dihydrolimonene 6:541 Ozone-triphenylphosphine adduct 4:554 oxidation ofylides with 4:558, 559 Ozonization reaction 14:416,417 with thujone 14:416,417 Ozonolysis 4:523;5:590;6:137,298,299; 8:139;9:338,359,525,527;11:337, 338,369;12:81 ;14:101 ;16:495,649, 712;20:409;21:417,432,712,714,715; 26:81,86;30:486,489 in steroid moiety synthesis 30:486 of ergosterol 30:489 cardanol methylether by 9:338 ofalkene 16:462 of diacetate 5:599 ofdiacet" 'irumamycin 5:599 of enol emer 16:495 of enyne 16:384 of ergosterol 16:336 of olefins 10:565 ofseleno ether 16:7 of stigmasterol 16:324,336 of streptolydigin 14:101 reductive 4:523 Ozonolytic cleavage 13:258,604 of (+)-A3-carene 16:258 Ozonolytic degradation 6:137 of 19'-hexanoylfucoxanthin 6:137 of peridinin 6:137 Ozoroa mucronata 5:824,830;9:316, 327;21:591 P substance 30:193 as pro-nociceptive 30:193
601
P 13 (phosphatidyl linositol)-kinaseindependent pathway 25:264 p l.Moraprenyl, p2_(ot_D_galacto_ pyranosyl) diphosphate 8:108 P-388 model 25:823 P-388 (mouse lymphoma) 30:691 phenolic triterpenes against 30:691 P-388 (murine lymphocytic leukemia) 30:588 activity of (-)-deoxypodophyllotoxin against 30:588 activity of (-)-yatein against 30:588 P-388 leukemia cells 21:263,414 P-388 lymphocytic leukemia cell 25:764 P388 mouse leukemia 12:390 staurosperine activity against 12:390 P-388 murine leukemia cells 21:411 P69 subtilases 25:391 Paccardi 26:1215 Pachastrella sp. 25:704;28:699 Pachiclavularia violacea 17:610 Pachodynerus erynnis 5:223 (+)-Pachydictyol-A 6:11 by reductive transposition 6:11 from Pachydictyon aociaceum 6:11 from c~-santonin 6:13 synthesis of 6:11,13 Pachydictyon coriaceum 6:11,70 (+)-pachydictyol A from 6:11,70 sanadaol (~-crenutal) from 6:70 Pachygone dasycarpa 29:578 Pachyman 5:288,317 antitumor activity of 5:317 Pachymatismin 25:717 Pachymeinopsis lanceolata 25:722 Pachymic acid 22:117;25:63,64 Pachypelilins 25:709 Pachypellina sp. 21:260;25:710 Pachyrrhizus erosus 24:779,822-826; 25:93 anti-feeding activity of 24:825 isoflavonoids of 24:823,824
Pachyrrhizus palmatilobis 24:822 biological activity of 24:823 chemical activity of 24:823 Pachysiphine 5:127,9:190 Pachystazone 20:670 from Salvia napifolia 20:670 Pachystima 18:741 Pacifagorgiol 9:254 from Pacifigorgia adamsii 9:254 X-ray crystal analysis of 9:254 Pacifigorgia adamsii 6:10;18:614,615 pacifigorgiol from 9:254 Pacifigorgiol 6:11 ;18:624,625 Clardy synthesis of 6:10 from Pacifigorgia admsii 6:10;18:624 synthesis of 6:10,11 Packed column GC 9:453-456 in gas chromatography 9:453-456 Paclitaxel 21:136;22:33;22:33;25:245 Padmatin 7:228 Paecilomyces lilacinus 26:432 Paecilomyces sp. 25:725 Paecilomyces variotti 2:341 ;12:103; 22:70 Paeon laciflora 21:584 Paeon mouton 21:584 Paeonia albiflora 22:508,528 Paeonia emodi 22:528 for epilepsy, convulsions,hysteria and hysteroepilepsy 22:528 Paeonia lactiflora 22:528 Paeonia officinalis L. 22:528 for epilepsy, hysteria and convulsions 22:528 Paeonia suffruticosa 22:528 for convulsions 22:528 Paeoniflorin 22:528,540;24:878-880 as neuromuscular blocker 24:878-880 Paeonol 21:584,585 PAF 30:594 antiplatelet activity of 30:594 PAF antagonist activity 24:740 of 2,6-diaryl-3,7-dioxa bicyclo [3.3.0.] octanes 24:740 PAF antagonists 24:854,1061-1085; 25:275,615
602
of Magnolia biondii 24:845,854 of Magnoliafargesii 24:854,862 PAF-antagonism 21:134 Paffic acid 7:5 PAF-induced inhibitors 26:240 (+)-acetoxypinoresinol dimethyl ether as 26:241 arctigenin as 26:241 arctigenin methyl ether as 26:241 chamigrenal as 26:244 cinnamophilin as 26:240 dehydroschisandrol A as 26:245 denudatin as 26:240 (+)-epipinoresinol dimethyl ether as 26:241 epiyangambin as 26:242 fargesin as 26:241 gomisin M as 26:240 honokiol as 26:240 (+)-isogmelinol as 26:241 isogmenolin as 26:241 isoyangambin as 26:242 justicidin B as 26:243 justicidin E as 26:243 kadsurenin H as 26:240 kadsurenone as 26:240 L-653,150 as 26:242 machililin G as 26:242 magnolol as 26:240 magnone A as 26:245 magnone B as 26:245 meso-dihydroguaiaretic acid as 26:240 methylpiperbetol as 26:243 neojusticin A as 26:243 phillygenin as 26:241 (+)-pinoresinol dimethyl ether as 26:241 piperbetol as 26:243 piperol A as 26:243 piperol B as 26:243 pregomisin as 26:244 puberulin A as 26:243,244 puberulin C as 26:243,244 schisandrol A as 26:245 (-)-syringaresinol as 26:243 taiwanin E as 26:243 taiwanin E methyl ether as
26:243 (+)-yangambin as 26:242 PAF-induced thrombocytopenia 26:242, 243 Pagicerine 5:128;9:181 Pagisulfine 5:126;9:172 Paicalein 30:70 Pain 30:191,194,203 control of 30:194 sensory component of 30:191 use of ginseng root in 30:203 with cannabinoids 30:194 Pain disorders treatment 192 by COX-2 inhibitor 30:192 Pain mechanisms 30:191 Pain mediator 30:192 cytokines as 30:192 glutamate as 30:192 histamine as 30:192 leukotrienes as 192 noradrenaline as 30:192 prostaglandins as 30:192 substance P as 30:192 Pain sensation 30:201 Pain transmission 30:194 Paitantin 4:588-590 synthesis of 4:588-590 Pakaraimoideae 23:531,553 Pal and Mukerjee 29:180 pisiferic acid synthesis by 29:180 Palaemon macrodactylus 22:79 Palasonin 26:457 Palauamine 25:770,771 Palauolide 10:152;29:111 activity in PLA bioassay system 29:111 Palauolol 29:111 activity in PLA bioassay system 29:111 Palindromic structure 25:371 Palisota ambigua 22:528 for epilepsy 22:528 Palladium (II) acetate 10:344 Palladium (0)-catalyzed condensation 12:300 Palladium (0)-catalyzed coupling 21:381 Palladium (0) 3:82,83 for macrocyclization 3:82,83
603
Palladium (0) catalyzed cyclization 8:228 ofallylic acetates 8:228 Palladium acetate 1:19 coupling with 1:19 Palladium black 14:763 as catalyst 14:763 Palladium catalysed acetalization 1:584 Palladium catalysed coupling 3:258 with [PdC12(PPh3)-Cu I)] 1:532 Palladium catalyzed rearrangement 14:625 Palladium coupling reaction 30:12 Palladium dehydrogenation 1:129,130 Palladium mediated coupling 10:341 regiospecificity of 10:341 stereochemistry of 10:342 stereospecificity of 10:341 Palladium mediated oxidation 12:241 Palladium-catalyzed biaryl coupling 29:407 rhazinilam synthesis by 29:407 Palladium-catalyzed coupling reaction 30:8 of vinyl iodide 30:8 Palladium-catalyzed cross-coupling reaction 30:17 Palladium-catalyzed cross-coupling 21:392 Palladium-induced indolizidine ring formation 12:299 Palladium-promoted reaction 16:367 ofvinylic bromide 16:367 (+)-Pallescensin A 10:409;18:17 from marine sponge 10:409 synthesis of 10:409 Pallescensin-1 6:31 from (R)-(-)-cyclocitral 6:31 palleseensin F from 6:31,32 palleseensin G from 6:31,32 synthesis of 6:31 Pallescensin-A 6:20,23 from Disidea pallescens 6:20,23 from trimethyl decalone 6:20 Gariboldi synthesis of 6:20 synthesis of 6:20,23 Pallescensin-C 6:69 Pallescensin-D 6:69
Pallescensin-E 6:31,32 from Disidea pallescens 6:31 frompallescensin-1 6:31,32 synthesis of 6:31,32 Pallescensin-G 6:31,32 from Disidea pallescens 6:31 from pallescensin-1 6:31,32 synthesis of 6:31,32 Pallidol 26:555,560 Palliferidin 5:722-724 Palliferinin 5:723 Pallinin 5:722-724 Palmatine 1:214;21:57,84,733 Palmitate esters 9:469 of spinasterol 9:470 Palmitic acid 9:315;25:333;26:434; 30:65,104 from carp oil 30:65 Palmitoleic acid 9:341;25:333 l'-O-Palmitoyl-3'-O-(6-sulfox-Dquinovopyranosylglycerol 25:868 N-Palmitoyl- S- [2,3-bis (palmitoyloxy) propyl]-L-Cys-Ser 18:926 Palmitoyltransferase 21:196 Palmrosa oil 25:132 Palomo's reagent 21:428,442 Palustrin 16:453 from Equisetum palustre 16:453 Palustrol 20:17 Palustroside I 25:97 Palustroside II 25:104 Palustroside III 25:104,106 hepatoprotective activity of 25:106 Palythoa 25:735 Palythoa sp. 26:69 Palythoa toxica 5:390 Palythoa tuberculosa 5:390,391,393 Palytoxin 3:209;5:390-394,403 Pamaquine 22:150 Panacene 25:786 Panagrellus redivivus 26:429,432,434, 435,438,450,455,467,473 Panagrolaimus 26:488 Panal 15:247 from Eupatorium trapezoideum 15:247 Panarine 13:387
604
Panax ginseng 10:153;21:638,665; 22:96,528 ;24:146,147,154,919;25:95 6;27:394,445 ;30:344 chikusetsusaponin III from 21:665 suspension cultures of 30:344 Panaxjaponicus 21:670 chikusetsusaponins from 21:670 Panax notoginseng 21:669;24:261263;25:476 dammarane saponins from 21:645 Panax quinquefolius L. 22:528 for convulsions 22:528 Panax sp. 21:645;27:686 saponins from 21:645 Panax zingiberensis 21:665 zingiberoside R1 from 21:665 Panaxacol 10:153 Panaxatriol saponins 21:669 Panaxynol 27:422 Pancratium maritimum 20:359;26:610, 613,615-617 N, O-dimethylnorbelladine from 20:359 Pancreatic acinar cells 18:857 Pancreatic acini 12:394 from rat and mouse 12:394 Pancreatic lipase activity 30:79,88,89, 90,94,108 effect of Platycodi radix on 30:79,88 effects of inulin extracts on 30:90 effects of Platycodi radix extract on 30:90 in vitro 30:88,90,94 inhibition of 30:79,108 Pancreatic lipase activity inhibition 30:86 by oolong tea 30:86 Pancreatic lipase inhibitor 30:83 orlistat (Ro 18-0647) as 30:83 Pancreatic spasmolytic polypeptide 27:805 Pandalus sp. 19:672 Pandanus amarillifolius 21:419 bilirubin from 21:419
holomycin from 21:419 pandamarine from 21:419 Pandanus odoratissimus 26:255 Pandaros acanthifolium 5:384;25:832; 28:710 Pandicine 5:129;13:393 Pandine 5:127 Pandine-type alkaloids 5:127 pandine 5:105 Pandoline 14:832 dehydrosecodine 14:832 from indoloazepine 14:831,832 from dehydrosecodine 14:832 from indoloazepine 14:831 synthesis of 14:831-833 20-epi-Pandoline 5:124 synthesis of 14:831-833 (+)-Pandoline 9:190 Panduratin A 23:821 Panicles 23:568 Pantherinine 23:270,272 Papsorbic acid 23:342 (6)-Paradol 23:818 (7)-Paradol 23:818 Paradol 23:818 (8)-Paradols 23:846 Pelargonidin 3-rutinoside 23:752 Pelargonidin derivatives 23:750 Pelorgonidin 23:742 Penaresidins 23:185 Penaresidin A acetate 23:195 Panek's synthesis 26:1224,1225 of dipeptide 26:1224 of [3-methylaspartate 26:1225 Panganensine R 26:1055,1057 Panganensine X&Y 26:1055,1057 Panic disorder 30:368,369 effect of circadian activity on 369 role of serotonin (5-HT) 30:368 Panicein-A 15:295 Panicein-B l 15:296 Panicein-B2 15:295 Panicein-B3 15:296 Panicein-Cl 15:296 Paniculatine 18:4 Paniculides 7:118 (R)-Panolactone 13:326 Panotima angularis 26:698 PAN-oxides 21:97
605
Pantalenolactone E-methyl ester 1:698, 700 synthesis of 1:698,700 Pantoea agglomerans 28:539 Pantoisofaranoid A 25:802 Pantoisofaranoid B 25:802 Pantoisofaranoid C 25:802 Pantolactone 16:475 R(R)-Pantolactone 3:252,253;8:140,141, 145-147,150 synthesis of 3:252,253 Pantolactone homologue [(3S,4S)dihydro-4-ethyl-3-hydroxy-4methyl-2(3H)-furanone] 10:442,443 absolute stereochemistry of 10:442,443 from Marshallia tenuifolia 10:442,443 synthesis of 10:442,443 Pantoneura plocamioides 25:801 Pantopyranoids A,B and C 25:801 Pantothenate synthetase 25:319 Papakusterol (glaucasterol") 9:36,37,41 from Pseudothesis species 9:37 from Sarcophyton glaucum 9:37 Papavarine 6:495;25:561 2,7-benzoxazacycloudeeine derivative from 6:495 Papaver oreophilum Rupr. 27:163 Papaver radicatum Rottb. 27:163 Papaver somniferum 17:633;18:45,54; 20:292;27:163 ;30:193 as analgesic 30:193 codeine from 30:193 morphine from 30:193 papaverine from 30:193 thebaine from 30:193 Papaver somniferum 30:193 as analgesic 30:193 Papaver sp. 21:488;27:158 Papaveraceae 21:3,733 Papaveraldine 8:265,266 synthesis of 8:265,266 Papaverine 21:97,98,102,109,488 Papaveroideae 27:161 Papaya 29:592 effects on caricain chymopapain 29:592
effects on papaya proteinase papain 29:592 (+)-Papilamine 2:181,182 13C-NMRshifts 2:182 structure of 2:182,182 Papilamine 2:205 (+)-Papilicine 2:205 13C-NMR shifts 2:205 structure of 2:178,182,183 Papilio 26:990 Papilio xuthus 18:682 Papillary carcinoma 26:712 Papillomas 26:693 Papillomavirus 30:405,394 cause of cancer 30:394 cause of papillomas 30:394 Paprika oleoresin 20:721 Papuamides A-D 25:714 Papuamine 24:573,650,658,659,665 Papulacandin 10:387 from gluconolactone 10:387 Papulin 26:592,593 Papulinone 26:592 Papyraceabromine-A 18:692 Paracaudina ransonetii 7:278 caudinoside A from 7:278 Paracentrone 6:136;10:153 Paracentrotus lividus 15:104 Paracoccidioides brasiliensis 5:307, 323,326;23:474 Paracoccidioides sp. 5:307,325,328 (S)-(-)-Paraconic acid 1:687 Paracresol 16:580 oxygenation of 16:580 (+)-Paradisiol 14:456-465 from (-)-7-epi-cyperone 14:453 from grape fruit oil 14:449 synthesis of 14:456-465 total synthesis of 14:453 5-epi-Paradisiol 14:456-465 (+)-dihydrocarvone 14:454 synthesis of 14:456-465 total synthesis of 14:454 Paraensidimmerins A and C 2:122 X-ray structure of 2:122 Paraherquamide A 26:490,491 ;28:331, 367 antiparasitic activity of 28:332 asymmetric synthesis of 28:367
606
conversion of PHB to 28:335 hydroxylation of MFA 28:335 total synthesis of 28:367 (+)-Paraherquamide B 28:359 conversion of MFA to 28:333 stereocontrolled synthesis of 28:358 Paraherquamides 28:331,332 synthesis of 28:332 Paraherquamides C-G 26:490 Paramecium 25:494 Paramuricea camaleon 6:72 Paramyxovirus 30:408 Parancistrocerus fulvipes 5:223-225 Parancistrocerus perennis 5:224 Parancistrocerus rufovestis 5:224 Parancistrocerus sp. A $:224 Parancistrocerus sp. B 5:224
Para-nitrophenyl-fl-D-glycopyranoside 25:306 Pararespula vulgaris 19:130 Parasitemia 25:329;30:596,694 induction by Plasmodium yoelii N67 cell line 30:596 Parasitemia inhibitor 30:597 in vivo 30:597 Parasiticidal activity 26:229 of lignans 26:229 Parasitmia 25:329 Parasorbic acid 13:539 Parastichopus californicus 15:87 holotoxins A, A~, B and B~ from 15:87 Parathymosin ot 8:433,434 Parathyona sp. "/:277 parathyonoside R from 7:277 parathyonoside T from "/:277 Parathyonoside R 7:277 from Parathyona sp. "/:277 Parathyonoside T 7:277 Paratocarpin L 28:229 biological activity of 28:229 Paratocarpus venenosa 29:773 Paratrichodorus 26:456 Paratylenchus hamatus 26:429 Paravespula vulgaris 14:526 2-methyl- 1,6-Dioxaspiro [4.5] decane from 14:526 Paraxanthine 22:6
Parbendazole 26:444 Parguerol 25:757 Parguerol triacetate 25:788 Parikh oxidation 12:305 Parikh-Doering oxidation 14:60 Parinari genus 28:36 Paris' polyphylla 22:528 for epilepsy 22:528 Paris' vietnamiensis 21:670 steroidal glycoside from 21:670 Parishin A 27:581 Parishin A-C 7:235,237 Park and Danishefsky 29:486 valienamines synthesis by 29:486 Parkeol 21:314,315 Parkia roxburgii 24:274 Parkinson's disease 22:310,343;25:531 Parmelia sulcata 5:313 Paromeria laevigata 24:275 Paromomycin 26:785,831 Parsons approach 12:24 for hexahydrobenzofuran component 12:24 of avermectins 12:24 Parthenim confertum 29:90 Parthenin 26:808,809;29:91 activity in TPA assay system 29:91 activity in EPP assay system 29:91 Parthenocissin A&B 26:567,568 Parthenolide 24:848,856;27:565,856; 29:88 activity in TPA assay system 29:88 activity in iNOS assay system 29:88 activity in NFkB assay system 29:88 activity in TNFc~, CRG assay system 29:88 activity in CRG assay system 29:88 antibiotic activity of 24:856 antinociceptive effects of 30:206 as anti-inflammatory 30:206 effect on NF-KB activation 30:206
607
Partial synthesis 6:157-160 of acetylenic carotenoids 6:157-160 of anguidine 6:225,226 of carotenoid sulfates 6:150 of gibberellins 6:186-194 Parus gambeli 5:836 hemoglobin components of 5:836 Parvaquone 26:804 Parvifoline 5:800,801 conversion to isoparvifolinone 5:800,801 Parvifoline A 15:118 13C-NMR of 15:132 from Rabdosia parvifolia 15:173 IH-NMR of 15:125 Parvifoline B 15:116 13C-NMR of 15:130 from Rabdosia parvifolia 15:173 ~H-NMR of 15:123 Parvifolinoic acid 15:174 from Rabdosia parvifolia 15:174 Parvifoliside 15:140 13C-NMR of 15:157 from Rabdosia parvifolia 15:173 IH-NMR of 15:148 Parvistemonine 21:770 Parvoviruses 30:394 Paspaline 21:79 Paspalitrem 21:79 Paspalum scrobiculatum 15:352-356 Paspalum utwillei 22:401 Passeer domesticus 5:836 hemoglobin components of 5:836 Passerini reaction 12:131,138 Passiflora 25:180,183 Passiflora coerulea 29:572 Passiflora incarnata 22:528 Passiflora quadranglaris 25:205,206 Passiftoraceae 25:180 Passive immunization 30:406 with hyperimmune globulin 30:406 Pasteurella multocida 4:196 riheptoses in 4:196 Patagonicoide A 28:603 NOESY correlations of 28:603
Patchaulol 25:125,170 Patchino ([3-patchouline oxide ) 11:56,57 Patchornik mehtod 12:120 cx-Patchoulene 4:677 [3-Patchoulene 4:677 (-)-[3-Patchoulene oxide 12:201,202 (-)-Patchouli alcohol 16:245 synthesis of 16:245 Patchouli alcohol 4:677;11:55;16:151; 21:584;25:170 [3-Patchouline oxide (patchino) 11:56,57 (-)-Patchoulol 8:423 (+)-Patchoulol 8:423-425 synthesis of 8:423-425 Pateamine 28:709 dilactone functionality of 28:709 total synthesis of 28:709 Patellamide A 4:93-99;25:879 revised structure 4:93-99 synthesis of 4:97-99 Patellamide B 4:93-99;25:879 revised structure 4:93-99 synthesis of 4:97-99 Patellamide C 5:419,420;25:879 cytotoxic activity of 5:419 revised structure 4:93-99 synthesis of 4:97-99 Patellamide E 25:879 Patellamide G(1) 25:879 Patellamides 4:93-99;28:624 as macrophage scavenger receptor inhibitor 28:624 X-ray crystallography of 28:624 synthesis of 4:93-99 Patellamides A-D 5:419,420;10:242, 243 Patellamides B 5:419,420 cytotoxic activity of 5:419 Patellazoles A-C 10:243;25:891 Paterno-Buchi photocycloaddition 10:440 Paterson's synthesis 26:1229;30:22-26 of discodermolide 30:22-26 of swinholide A 26:1229 of iso-swinholide A 26:1229 Pathenolide 7:117,120
608
Pathogenesis-related gene expression 25:394 Pathogenic bacteria 30:421 Legionella pneumophila 30:421 Pseudomonas aeruginosa 30:421 Shigella boydi 30:421 Pathogenic fungi 5:598 Alternaria kikuchiana 5:598 Botrytis cinerea 5:598 Piricularia oryzae 5:598 Pathogenic toxins 6:538 Pathogen-induced necrosis 25:660 Pathogen-induced oxygenase 26:947 Pathological anxiety 30:376 role of serotonin (5-HT) in 30:376 Pathophysiological inflammatory reactions 30:744 Patinopecten yessoensis 17:20;19:579; 28:653 Patiria miniata 15:55 miniatoside A and B from 15:61 patirioside A from 15:48 Patiria pectinifera 7:297,302;15:61 Patirioside A 15:48 Patrinia intermedia 22:528 Patrinoside 7:441 Pattende's synthesis 12:180,181 of verticillene 12:180,181 Patuletin 3-glucoside 7:227 Patulin 24:458;26:449 FPTase inhibition by 24:458 Paulsen method 6:357 Pauly's reagent 17:396 Pauridiantha lyalii 26:1036 Pauson-Khand cyclization 3:83,84 Pavinan alkaloids 30:217 Pavine alkaloids 6:471 Pavine-benzyltetrahydroisoquinoline dimer 30:583 Paw oederma 30:207 inhibition of 30:207 Paxilline 21:79 Paxillus atrotomentosus 29:288 Paxillus atrotomentosus var.bambusinus 29:273,274 Payne rearrangement 4:173,179,186, 344;11:10,36,38;12:209
PBG (porphobilinogen) 9:591-593,596, 607 oligomerization of 9:595 PBG deaminase 9:592-597,604 PBP-2 4:433 PBS (phosphate buffered saline) 25:455 PbTx-2 21:300,301 PCC Oxidation 6:545 Pd(O)-catalyzed carbonylation 10:29 PDC oxidation 16:23 Pd-catalyzed cross coupling reactions 10:161-163 PDE-1 1:163,164,178-180 synthesis of 3:306-319 PDE-I Dimer 3:331 synthesis of 3:331 PDE-II 1:163,164,178,180 Pectachol 7:224 Pectenol A,B 6:147 2-Pectenotoxin 19:580 cytoxic activity of 19:580 Pectenotoxin 25:2 25:729 Pectenotoxin-1 and-2 17:19,20 Pectenotoxin-3 17:20 Pectenotoxin-4 19:579 Pectin esterase 25:486 Pectinase 25:483,485 Pectinasic enzymatic activity 24:995-998 Pectinioside E 15:47,48 Pectinioside G 15:57 Pectinophora gos~ypiella 20:25,20:28 Pectinosides A-F 7:290,293,304 Pectolinarigenin 7:227;30:725,748 antispasmodic activity of 30:748 from Salvia limbata 20:712 structure of 30:725 Pedaliaceae 7:407,417,423 Pedamide 1:623 enantioselective synthesis 1:623 (+)-Pedamine 14:499 synthesis of 14:499 Peddiea fischeri 22:471 Pederin 5:336;14:499;26:1233,1234 Pediastrum simplex 26:379 (-)-Peduncularine 11:284;13:491,492 absolute configuration of 11:284 from (S)-malic acid 11:284,285
609 synthesis of 11:284,285;13:491, 492 Peduncularine 9:178 Pedunculariside 29:84 activity in COX assay system 29:84 activity in EPP assay system 29:84 Peduncularistine (18,19-dehydroaristotelin- 15-one) 9:171 (+)-aristoserratine from 11:296 Peganum harmala L. 2:369;22:529; 26:828 for hysteria 22:529 Pelagococcus subviridis 6:135 Pelandjauic acid 9:316 Pelargonidin 26:748 Pelargonidin (anthocyanidin) 29:585 effects on LELA 29:585 effects on MMP 29:582 Pelargonidin-3-rutinoside-5-glucoside 5:658 Pelargonidin-4,5-diglucosides 5:658 Pelargonium fragrans 7:112 Pelargonium graveloens 7:100,101; 27:375 Pelargonium hortorum 21:591 Pelargonium roseum 27:377 Pelargonium sp. 7:95,96,100,112; 29:582 Pelargonium xhortorum 30:146 for pest resistance 30:146 Pelenolide 7:230 Pellegata oxidation 19:226 Pellia endiviifolia 2:278,279 Pellia sp. 2:90 Pellina sp. 5:419;21:260;25:709,723 Pellitorine 10:152 from Anacyckus pyrethrum 10:162 Pelmatozoa 7:265,266 c~-Peltatin 5:481,483;26:193 [3-Peltatin 5:481,483,493;26:193 methyl ether of 26:193 (+)-[3-Peltatin A methyl ether 18:586, 589,592,596 Peltatins 26:222 Peltigera aphtosa 5:313
Penaeusjaponins 25:718 Penaeus vannamei 19:628 Penam carboxylic acid 12:127-129 synthesis of 12:127-129 Penam derivatives 12:127 Penam product 11:212,213 by isopenicillin-N-synthase 11:212,213 formation of 11:213 from cx-aminobutyrate 11:212, 213 stereochemical course of 11:213 Penares sollasi 23:194 Penares sp. 28:460;713 as ct-glucosidase inhibitor 28:713 penarolide sulfate A from 28:713 Penaresidin B acetate 23:195 Penazetidine A 23:194 Pentacylic pyridoacridine alkaloids 23:273 1,5-Pentanediol diacetate 188 Pentathiepins 23:236 19-O-n-Pentyldamavaricin Fc 23:97 n-Pentyldamavaricin Fc 97 Peonidin 3-rutinoside 23:746 Peptide 23:341 Peralillo 23:657 Perfused organ system 23:12 Peridinin 23:178 Peritassin A 676 Peritassine B 23:676 Peroxyplakoric acid A1 23:341 Penaresidines 18:460 from Penares sp. 18:460 Penaustrosides A and B 15:91 DSfromPentacta australis 15:91 Pencillium raistrickii H10BA2 24:933 Pendolmycin 15:456,462 tumour promoter activity of 15:462 Penduletin 7:227;30:726 structure of 30:726 Penems 4:448,476 absolute stereochemistry of 4:435 by azetidinone synthesis 4:437 synthesis 8:262 Penicillic acid 26:449
610
Penicillins 4:432,433,435,442;6:385; 9:413;17:614-617;30:738 biosynthesis of 11:211-213 cephalosporin C from 11:211-213 chemical shifts of 4:442 from 5-(L-c~-aminoadipoly)-Lcycteinyl-D-valine (LLD-ACV) 11:211-213 semi synthesis of 17:614-617 Penicillin derivatives 12:129-131 synthesis of 12:129-131 Penicillinates 4:437 stereoselective reduction 4:437 Penicilliopsis clavariaeformis 22:649 Penicillium 25:828,901 Penicillium alladadense 5:300 Penicillium allii 21:622 Penicillium atrovenetum 19:117;23:268 Penicillium brefeldianum 11:192 Penicillium brevicompactum 5:299, 13:553 ;17:475;19:168 Penicillium calaviforme 5:300 Penicillium carneum 26:490 Penicillium caseiculum 13:305 Penicillium charlesii 5:296,299; 26:490,1128 Penicillium chrysogenum 5:299,300, 15:351 ;17:616;21:607,608; 22:263;26:1281 Penicillium citrinum 5:300,13:553, 19:168;22:251 Penicillium cyclopium 28:119 Penicillium digitatum 12:103; 25:138-140,145,148,149 Penicillium erythromellis 5:300 Penicillium expansum 5:299;7:13, 14;26:228 Penicillium frequentans 4:588 Penicillium griseofulvum 9:341 ;22:80; 23:343 Penicillium hirsutum 21:622 PenicilIium islandicum 5:299,300; 21:413 ;22:649;24:341 ;28:134 Penicillium italicum 25:150 Penicillium javanicum 5:299 Penicillium luteum 5:299 Penicillium madriti 11:198 Penicillium nigricans 26:805
Penicillium notatum 7:71;17:615; 21:221 ;329;25:770,780 glucose oxidase from 7:71 isocyanide xanthocillin from 21:329 xanthocillin from 21:221 Penicillium ochrochloron 5:300 Penicillium oxalicum 27:849 Penicillium palitans 4:588-590 Penicillium paraherquei 26:490;28:331 Penicillium patulum 5:300;11:198 Penicillium raistrickii 5:300;29:269 Penicillium raistrickii H10BA2 24:933, 938,939,940,944,963,965 Penicillium roqueforti 13:305;25:129; 26:490;28:331,332 microbial hydroxylation of 28:346 reaction of 28:336 spiroalkyl analogs of 28:355 Penicillium rugulosum 10:646 Penicillium scleriotorum 5:299 Penicillium sp. 5:299,301,325,326; 17:475 21:198,204,224; 24:933-972 ;25:155,797 ;26:450,482 bioactive compounds of 24:933-972 taxanes from 24:942-943 taxol production of 24:933-972 Penicillium thomii 22:627 Penicillium turbatum 11:194 antibiotic A 26771B by 11:194 Penicillium urticae 21:240;22:266 patulin from 21:240 Penicillium varians 5:300 Penicillium wortmannii 21:238 wortmannin from 21:238 Penicillium zacinthae 5:300 Penicillus dumetosus 18:688 Peniophora 26:462 Peniophora filamentosa 29:265 Peniophora gigantea 29:265 Peniophora sanguinea 29:293,294,298 biosynthesis in 29:298 Penitrem 21:79 Pennisetum glaucum 29:593 Pennogenin 2:445;21:660 Pennyroyal oil 25:156
611 Penstemide 7:441 activity against P-388 lymphocytic leukemia 16:295 from Penstemon deutus Dongl. ex. Lindl. 16:295 synthesis of 16:295 Penstemon barbatus 24:799,836-837 iridoid glycosides of 24:836,837 Penstemon campanulatus 24:837-838 cytotoxic activity of 24:837 iridoid of 24:837,838 Penstemon gentianoides 24:839 Penstemon linarioi 27:837 phenylethanoid glycoside from 27:837 Penstemon rosseus 24:838 anti-fungal activity of 24:839 iridoid of 24:838 Penstemonoside 7:486 Pentaacetyl gluconic acid 30:450 Pentaacetyl pyranoses 14:663 1,2,4,7,8-Pentaacetyl-D-glucooctopyranose derivatives 11:468 Pentabromopsendilin 21:298 Pentabromopseudoline 25:776 Pentacenediquinone 11:122 5,7,12,14-Pentacenediquinone 11:124 Pentacenequinone 11:121-123 from naphthacenequinone 11:123 pentacenediquinone 11:122 synthesis of 11:121,122 Pentaceraster alveolatus 7:290, 304-306;15:46,61 6-epi-nodosides from 7:34 nodososide from 7:298 Pentacta australis 15:91 DS-penaustrosides A and B from 15:91 Pentacyclic triterpenes 30:207 protein kinases inhibition by 30:207 Pentacyclic triterpenoid esters 9:460 Pentacyclic triterpenoids 25:55 fridelane 25:55 glutinane 25:55 hopane 25:55 lupane 25:55 moretenane 25:55
multiflorane 25:55 taraxastane 25:55 taraxerane 25:55 Pentacyclopropane core 21:397 3-[(Z)-Pentadec-8-enyl] phenol 9:323 Pentadecadeoxy nucleotide 13:261 1-Z-8-Pentadecadiene 2:8 CI (NO) mass spectrum 2:8 6-Pentadecatrienylsalicyclic acid 21:593 5-Pentadecenal 26:75 wittig reaction of 26:75 5-Pentadecen-l-ol 26:75 6-(Pentadecenyl) salcyclic acid 5:825 13C-NMR spectrum of 5:825 form alkyllithium 5:826 1H-NMR spectrum of 5:825 synthesis with metallic salts 5:826 6-(10'-Z-Pentadecenyl) salicyclic acid 5:825 ~3C-NMR spectrum of 5:825 ~H-NMR spectrum of 5:825 3-Pentadecyl phenol 2:280,281 ;9:323, 343 6-Pentadecyl salicylic acid 2:280,281 5-Pentadecylresorcinol 21:592,593 Pentadecylresorcinol 9:314 6-Pentadecylsalicyclic acid 21:592,593 (2E,4E)-2,4-Pentadienamide 10:155 Pentadienols 9:572 asymmetric hydroxylation of 9:572 Pentadin 15:36 Pentadiplandra brazzeana 27:18,19,38 brazzein from 27:18 pentadin from 27:19,38 Pentaene 6:292,293 from octatrienal 6:292,293 Pentafubalol 20:273 Pentagalloyl glucose 22:508,528,540 Pentagastrin 25:613 Pentaglycosides 7:276,286,287,289, 290;28:601 from sea cucumbers 28:601 3fl, 6a, 16fl,24a,25-Pentahydroxy-9fl, 19cyclolanostane 25:184 Pentahydroxy-agarofuran 18:744
612
2c~,3[3,1213,20S,25-Pentahydroxydammar-23-ene 18:650 3,5,7,3',4'-Pentahydroxyflavone 27:841 3 [3,1613,2113,23,28-Pentahydroxyo lean12-ene 18:650 A4-3[3,6~,8,15ct, 16[3-Pentahydroxysteroids 15:64 2,3,4,5,6-Pentahydroxyxanthone 25:350-351 Pentaketides 21:207,208 Pentalenene 13:6-8 synthesis of 13:6-8 epi-Pentalenene 3:6,61 Pentalenene 3:8,9,12,19,25,44 synthesis of 3:8,9,12,19,25,44 Pentalenic acid 3:6,61 epi-Pentalenic acid 3:6,61 Pentalenolactone 13:6,26;21:230 biosynthesis of 13:30 Pentalenolactone antibiotic 18:7-10 Pentalenolactone E 13:29,30 methyl ester 13:29,30 Pentalenolactone P 13:30-32 methyl ester 13:30-32 Pentamera calcigera 28:598 calcigeroside B from 28:598 Pentamethyl ether 17:459 qS-Pentamethylcyclopentadienyl 21:222 Pentamidine (pentacarinat(R)) 26:791, 793 Penta-N, O-acetyl valiolamine 13:199 (+)-Penta-N, O-acetyl-validamine 13:196 Penta-N, O-acetylvalienamine 13:198 Pentane 9:564 as marker 9:564 in lipid autoxidation 9:564 (2R,4R)-2,4-Pentanediol 14:507,508 acetal from 14:507,508 (2R,4R)-2,4-Pentanediol acetals 1:605 diastereoselective allylation 1:605 (2R,4R)-2,4-Pentanediol ketals 1:591, 594 diastereoselective reductive cleavage 1:591,594 Penta-N-O-acetyl-dl-validamine 10:521 stereoselective synthesis of
10:521 synthesis of 10:518-521 3-Pentanone 30:10 aldol condensation of 30:10 Penta-O-acetyl-D-galactose 21:162,165, 166 Penta-O-acetyl-D-gulopyranose 14:659-664 synthesis of 14:659-664 Penta-O-acetyl-D-iodopyranose 14:659-664 synthesis of 14:659-664 Penta-O-acetylgalactofuranose 14:232 1,2,3,4,6-P enta- O-galloyl- D-D-gluc o se (galloyl ester) 29:589 effects on PEP 29:589
Nl,N4,N7,Nl~
yl-
spermidine (coumaroyl amide) 29:573 effects on HIV- 1 protease 29:573 Pentapeptide dolastatin 25:885 Pentapeptolide 21:408 Pentapora fasciata 18:715 Pentaquine 22:150 Pentasaccharides 10:475,476 by glycosylation 10:475,476 synthesis of 10:475,476 Pentaspadon motleyic 9:316 Pentaspadon officinalis 9:316 1,2,3,5,6-Pentathiepanes 25:843 Pentenal 11:343,344 from (S)-(-)-citronellol 11:343, 344 methyl-substituted 11:343,344 Pentenolides 10:11,12 Pentenylation 12:466 Pentobarbital 30:62 Pentodialdofuranose 4:190 Wittig olefination of 4:190 Pentosan polysulphate 30:412 Pentoses 30:430 as substrates 30:430 6-Pentyl-2H-pyran-2-one 21:196 n-Pentylmagnesium bromide 21:386 2-n-Pentylquinoline 26:820 6-Pentyl-~,-pyrone 13:297 PEP (phosphoenolpyruvate) 11:182 Peppermint 26:745
613 Pepstatin 12:476 synthesis of 12:476 Pepstatin (L-valyl-L-valyl-(3S,4S)statinyl-L-alanyl-(3S,4S-statine) 12:432,433 Pepticinnamins 24:438,439 structure of 24:439 ot,?-trans-Peptidation 6:410-412 Peptide 9:537-557 from bacteria 9:537-557 semi-synthesis of 17:646 siderophores 9:537-557 tandem mass spectrometry of 9:537-557 Peptide antagonists 18:863-865 Peptide cross linkages 2:19-42 Peptide derivatives 12:155 Peptide elicitors 25:393,395,397 Peptide enod 25:40 25:379 Peptide hormones 27:794,798 Peptide prohormones 25:387 Peptide signals 25:387,388 Peptide-antagonists 24:910-913 Peptides 24:522,527-533,802, 1017-1019,1078;27:804 as antiviral compound 24:522, 527-533 biological activity of 27:804 from animal tissues 27:802 from plant tissues 27:802 Peptidoglycan 6:385-420 biosynthesis of 6:404 relation of sugar-peptide structures to 6:385-420 Peptidoglycan-related compounds 6:404-420 structural confirmation of 6:406 Peptidoleukotrienes 30:225 type of leukotrienes 30:225 Peptidomimetic chemistry 12:477 Peptidonimetic inhibitors 25:39 Peptidophospogalactomannan 5:301 Peptidorhamnomannans 5:324 Peptidyl transferase 7:387 Peptolide 10:280;21:408 Peptostreptococcus sp. 25:925 Peracid oxidation 14:320-324 of guaiazulene 14:320-324 Peraksine (vomifoline) 13:389
Perezinone 5:771,772 allylic oxidation 5:772 derivatives of 5:771,772 structure of 5:771,772 a-Perezol 5:765,767,781,782 synthesis of 5:799 [3-Perezol 5:781,782 ),-Perezol 5:781,782,786 Perezone 5:763-813 chemistry of 5:763-813 Diels-Alder reactions of 5:768 intramolecular cycloaddition 5:782 structural modifications of 5:798 synthesis of 5:769,770 transformation to pipitzol 5:792-800 (-)-Perezone 8:39 Perforene 6:30;10:182 from chamigrene precursor 6:30 from Laurencia perforata 6:30 structure confirmation of 6:30,31 Perforenone 6:29,30,32,33 epiguadalupol from 6:30 from cyclophptenone enolate 6:29,30 from Laurencia perforata 6:29 guadalupol from 6:30 Majetich synthesis of 6:32,33 synthesis of 6:29,30,32,33 Perfragilins A and B 25:825 Perhydroazulene 1:547 Perhydroazulene synthesis 1:541-556; 3:44 Perhydrogenation 6:149 of (3R,3 R ~)-zeaxanthin 6:149 (-)-Perhydrohistrionicotoxin 16:443 synthesis of 16:480 (+)-Perhydrohistrionicotoxin 19:14, 19:17 Perhydroindane esters 6:179,180 preparation of 6:179,180 Perhydroisoindol- 1-one 15:355 Perhydronaphthalene derivative 6:179, 180 Perhydrophenanthrene group 6:54-58 Perhydrophenanthrene skeleton 1:661 synthesis of 1:661
614 Perhydroquinolines 25:859 Peri interaction 1:386 Periandra dulcis Mart 15:26;27:15, 16,30 periandrin from 7:142 periandrin I from 27:16,30 periandrin II from 27:16,30 periandrin III from 27:16,30 periandrin IV from 27:16,30 periandrin V from 27:16,30 Periandra mediterranea (Vell.) 15:26;27:16,30;27:15,16,30 periandrin I from 27:15,30 periandrin II from 27:16,30 periandrin III from 27:16,30 periandrin IV from 27:16,30 Periandradulcins 15:191 Periandric acids I-IV 7:142 Periandrin I 15:22;27:15,30,31 structure of 27:31 Periandrin II 27:16,30,31 structure of 27:31 Periandrin III 27:16,30,31 structure of 27:31 Periandrin IV 27:16,30,31 structure of 27:31 Periandrin V 27:16,30,31 structure of 27:31 Periandrins 7:142 Periandrins I-IV 15:26 Pericaria 22:634 Pericentral hepatocyte necrosis 25:466 Periconia byssoides 25:790;29:479 Pericosine A 25:790,791 [2cy+2cy+2~]-Pericyclic reaction 16:621 [2~+2~+2~]-Pericyclic reaction 16:628 Pericyclic reactions 3:418 of arynes 3:418 Pericyclivine 5:124;9:171 Peridiain 30:522 structure of 30:522 Peridinin 6:133,134,136,137,141,142, 145;10:153 ;20:581,583 stereoisomer of 6:139 synthesis of 6:144 Peridinin derivatives 6:135,136 Peridininol 6:136,142,143 (S)-Perilla alcohol 11:324 oxymercuration of 11:324
Perilla alcohol 19:214 Perilla frutescens 15:5;21:605608;27:13,20 Perillaldehyde 20:6;21:607,608,610, 622;25:146,147 ;29:83 activity in AM assay system 29:83 activity in RAS assay system 29:83 (-)-Perillaldehyde 14:361 ;16:245 perillic acid from 6:545 (-)-sirenin from 6:545,546 S-(-)-Perillaldehyde 16:230 (R)-(+)-Perillaldehyde 19:205;16:230 (+)-Perillaldehyde 19:206 Perillartine 15:14;27:10,13,20 as sweetener 27:10 structure of 27:20 Perillene 14:506 chiral acetals from 14:506 Perillic acid 6:545;25:145,146,147,150; 29:83 activity in NFkB assay system 29:83 from (-)-perillaldehyde 6:545 iso-Perillic acid 29:83 activity in RAS assay system 29:83 activity in RAS assay system 29:83 Perillyl alcohol 21:607;25:146,147,148, 149,150;28:426;29:83 activity in colon-1 assay system 29:83 activity in lung-1 assay system 29:83 activity in mam-2 assay system 29:83 activity in AP assay system 29:83 activity in APO assay system 29:83 activity in DIF assay system 29:83 activity in NFkB assay system 29:83 activity in RAS assay system 29:83 activity in UVB assay system
615
29:83 as bioactive monoterpenoid 28:426 Perindrins I-IV 7:142 from Periandra dulcis 7:142 Periodate 2:346 oxidation of glucoamylase 2:346 perrottetianal 2:278,280 Periodate-nitromethane procedure 4:240 for purine synthesis 4:240 Peripheral analgesic properties 26:400, 415 Peripheral nervous system 30:194 cannabinoid receptors in 30:194 Peripheral neuropathy 26:1130 as syndrome type-lA 26:1130 Peripheric antinociceptive effect 26:416 trans-anti-Periplanar fashion 11:301, 302 Periplaneta 26:991 Periplaneta americana 6:538;8:182, 221 ;9:488-490;22:377,397 ;26:991 Periplaneta bunnea 8:182 Periplanetajaponica 8:182 (+)-Periplanone 8:182 synthesis of 8:182 Periplanone-A 6:538,539 (-)-Periplanone-B 6:541,542;16:218 from (+)-dihydrolimonene 6:541,542 synthesis of 6:538-542;16:218 Periplanone-B 182,226,227 synthesis of 8:179-182,226,227 Still's synthesis of 8:247-249 Periploca sepium 24:273,289 Periscogenin 7:228 Periselectivity 1:569,570 Peritassa 18:754 Peritassin A and B 18:755 Perivine 5:112,114 Periwinkle 4:29 Perkin condensation 12:381 intramolecular 12:381 Permeation 30:800 ofopioid analogues 30:800 Permethyl cyclopentanone 8:4,5 synthesis of 8:4,5 Permethylated (meso)-pentitols 4:182 Permethylated L-arabinitol 4:18,182
Permethylation 5:199 Permethyl-O-rhamnose moiety 27:879 Permethyl-[3-cyclodextrin 13:328,329 Perna canaliculus 25:864;28:656 Peronosporales 9:203 Peroxidase 14:820,821;21:356;25:657, 663 Peroxidase-catalyzed dimerization 27:765 ofp-coumaryl-hydroxy oxyagmatine 27:765 ofp-coumaryl-hydroxyagmatine 27:765 Peroxidase-catalyzed reactions kinetics 27:741 Peroxidase-mediated oxidation 27:777 of (+)-catechin 27:777 Peroxidases 27:735,755 for synthesis of natural bioactive alkaloids 27:778 from grapevine 27:756 in synthesis bioactive alkaloids 27:788 in synthesis ofbioactive plant phenols 27:755 Peroxidized oil-treated group 27:408 Peroxisomes (microbodies) 22:343 Peroxisomicine A~, A2, A3 22:563,564, 588,590,592,593,596,598,599,600, 601,602 Peroxisomicines 22:568,570,582,594, 596 3c~-Peroxyarmefolin 27:550 5ct,8c~-Peroxycholesterol 5:406 cytotoxic activity of 5:406 Peroxyparthenolide 27:566 Peroxyplakoric acid A1 methyl ester 23:344 Petrosolic acid 23:218 Petunidin 23:742,748 Phaseollinisoflavan 23:342 Phenazine analog 23:166 Phenolic metabolism 23:741 Phenylalanine ammonia lyase (PAL) 23:741 Phenylalanine 23:234,740 Phenylethylamine 23:234
616
(R)-Phenylglycine methyl ester (PGME) 23:203 (S)-Phenylpropanoid glycosides 23:487,521 Phenylpropenoids 23:740 Phillyraeoidin A 23:403 Phillyraeoidin B 23:403 Phillyraeoidin C 23:403 Phillyraeoidin D 23:403 Phloretic 2'-glucoside 23:745 Phloridzin 23:745,746 Perpenthylated-[3-cyclodextrin 27:368 Perrotetin E 2:285;20:280 Perrottetins E-G 2:283,284,285 Persea americana 22:395;23:342; 25:943;29:593 Persea indica 26:850,851,852 cinnzeylanol from 26:850 cinnzeylanone from 26:850 epi-cinnzeylanol from 26:850 idicol from 26:850 innzeylanine from 26:850 perseanol from 26:850 ryanodanes from 26:850 ryanodol from 26:850 ryanodol- 14-monoacetate from 26:850 vignaticol from 26:850 Persea major 9:402 Persea obovatifolia 26:219 obavatifol from 26:219 obovaten from 26:219 obovatinal from 26:219 perseal A&D from 26:219 Perseal A-D 26:202,219 Perseanol 26:850 Persia thunbergii 28:419 Persoona elliptica 9:320,355 Persoonal 9:320 Persoonal dimethylether 9:355 synthesis of 9:355 Perthamide B 26:1187 Perulactone 20:194,223,224,241 Perun conformation 13:156,157 Pervasive development disorder (PDDs) 30:372,384 Asperger's syndrome (AS) 30:372 autistic disorder (AD) 30:372
childhood disintegrative disorder (CDD) 30:372 effect on social skills in 30:372 group of 30:372 Rett's disorder (RTT) 30:372 Pervasive development disorder-not otherwise specified (PDD-NOS) 30:384 Pervicosides A, B and C 15:92 (-)-Pessione 26:823 Pestaliotopsis longiseta 21:204 epiepoxydon from 21:204 (+)-harveynone from 21:204 oxysporone from 21:204 Pestalotan 5:308 Pestalotan polyol 5:319-321 antitumor activity of 5:391,320 Pestalotia sp. 5:307,308 antitumor activity of 5:319 Pestalotin 1:637,638;21:198 enantioselective synthesis of 1:637,638 Pestalotis cryptomeriaecola 21:198 Pesticidal activity 18:196 of staurosperine 12:397 Pesticides 9:383,391 Petasin 29:87 activity in 5LOX assay system 29:87 activity in PLA assay system 29:87 activity in PAF assay system 29:87 Petasinecine 1:237 enantioselective synthesis of 1:637,638 Petasites hybridus 29:87 Petchia ceylanica 5:135,140,147, 149,173 Petchicine 9:190,192 Petersaponin I 21:673 Petersianthus macrocarpus 21:673 Peterson olefination 3:202;8:247,248; 11:10,11;19:374 in [3-dictyopterol synthesis 6:19,189 (-)-Petiodial 16:310 from Udotea petiolata 16:310
617 Petitgrain oil 27:373 from leaves 27:373 from twigs 27:373 Petiveria alliacea L. 28:403 Petrocaulon purpurascens 22:348 Petrosapongia nigra 25:697 Petrosapongiolides 25:697 Petroselimum crispeum L. 25:666 Petroselinum sativum 22:457 apigenin-7-O-apiosyl-glucoside from 22:457 Petrosia contignata 25:713 Petrosia ficiformis 9:42 26- dehydro- 25- epiap lys tero 1 from 9:40 dihydrocalysterol from 9:37 (23R,24R)-23,24-methylenecholesterol from 9:37 Petrosia hebes 9:37 dihydrocalysterol from 9:37 hobesterol from 9:37 petrosterol from 9:37 Petrosia seriata 21:267;25:694 petrosin A,B,C from 21:267 Petrosia sp. 25:722,723 Petrosia weinbergi 25:703;28:705,706 antiviral activity of 28:705 antiviral metabolites from 28:706 orthoesterol disulfate A from 28:705 orthoesterol disulfate B from 28:705 orthoesterol disulfate C from 28:705 weinbersterol disulfate A from 28:706 Petrosterol 9:36,37,40-43 biosynthesis of 9:41-43 from Cribrocalina vasulum 9:37 from Helicondria species 9:37 from Petrosiaficiformis 9:37 from Petrosia hebes 9:37 synthesis 9:37 Peturin chloride 20:738 Peucedanum ostruthium (L.) 29:699 Peumus boledus 22:32,354 Peyssonelia sp. 25:694 Peyssonols A 25:694
Peziza vesiculosa 5:277;23:118,133 Pezizales 9:203 Pfaffia baniculata 7:135 pfaffic acid from 7:135 pfaffosides A-F from 7:135 Pfaffic acid 7:135 from Pfaffia paniculata 7:135 X-ray analysis of 7:135 Pfaffosides A-F 7:135 from Pfaffia paniculata 7:135 PGE2 25:463 as down-regulator of TNF-a 25:465 P-glycoprotein 21:158 PGM 6:385 antimetastatic properties of 6:386 PHA 25:271 Phaca (L.) 27:444 Phaeocystis sp. 6:135 PhaJfia rhodozyma 7:361 (3R,3'R)-astoxanthin from 7:321 Phag-inhibitory activity 26:187 of Melia azedarach 26:187 Phagocytes 22:343 Phagocytic activities 21:651 Phagocytic cells 22:112 Phagocytic chemiluminescence 24:142 Phagocytosis 21:96;24:140-142 Phakallistatin 25:5 25:830 Phakellia 25:847 Phakellia cardus 23:216 Phakellia costata 25:830;28:683 Phakellia flabellata 21:270 Phakellia mauritiana 25:770 Phakellins 21:270 Phakellistain 25:429,715,716 pharmacological effects of 25:429 Phakellistatin 5 28:683 as cytotoxic heptapeptide 28:683 Phalacrocorax niger 5:837 hemoglobin components of 5:837 Phalloidin 21:96 Phallusia manillata 10:249 Phanerochaete chrysosporium 13:309; 26:186,1014 Pharaoh ants 6:445
618
Pharbitis purpurea 19:247 Pharmaceutical importance 23:497 of acaciaside 23:497 Pharmacodynamic effects 23:12 Pharmacodynamic properties 30:799 of opioid 30:799 Pharmacodynamics 23:19 Pharmacognosy 13:629-669 Pharmacokinetic parameters 30:501 of 1a,25(OH)2D3 30:501 of 1c~,25(OH)2D4 30:501 Pharmacokinetic properties 30:799 of opioid 30:799 Pharmacokinetic studies 30:500,811, 818 of 1a,25(OH)2D analogue 30:500 ofdi (DTOH) 30:811,818 of tripeptide (DTAOH) 30:811,818 Pharmacokinetic trials 30:592 Pharmacokinetics 21:258;23:19 Pharmacological actions 27:393,431; 30:55 of Baicalein 27:431 of natural products 30:55 Pharmacological activity 10:115-117; 21:4,278,457 ;23:247,797; 24:875-926;30:287,603,797,813 of acylphloroglucinols (hyperforins) 30:603 of aulacocarpinolid 23:797 ofaulacocarpin A 23:797 ofaulacocarpin B 23:797of biflavones 30:603 ofdeltorphin C 30:813 of dermorphin 30:813 of D-glucopyranosyl moiety 30:813 of flavonoids 30:287 of flavonol glycosides (quercetin) 30:603 of Kampo medicines 24:875-926 of Labiatae family 30:287 of metabolites 30:603 of naphtodianthrones (hypericins) 30:603
of quinocarins 10:115-117 ofningalin A 23:247 ofningalin B 23:247 of ~t receptor agonists 30:797 of p receptor antagonists 30:797 of 8 receptor agonists 30:797 of 5 receptor antagonists 30:797 of rc receptor agonists 30:797 of K receptor antagonists 30:797 Pharmacological approaches 30:55 Pharmacological bioassay 30:801 of la opioid receptor 30:801 of 6 opioid receptor 30:801 Pharmacological effects 25:429 of phakellistain 25:429 Pharmacological profiles 30:762 of Chlorella 30:762 of green algae 30:762 Pharmacological properties 22:735; 26:556-559;27:767,844;30:843 of earthworm fibronolytic enzymes (EFEs) 30:843 oftropane alkaloids 22:735 of resveratrol oligomers 26:556-559 Pharmacological responses 21:100 Pharmacological studies 21:748;30:304 ofBgt A 21:754 of quinones 30:303 Pharmacologically active compounds 24:848-858 Pharmacologically active polymers 30:395 Pharmacophore 4:434;21:257 ;30:196, 198 in carbapenem 4:434 of 3-alkyl-5-arylimidazolidinediones 30:198 Pharmacophore models 12:264 Pharoah ant trail pheromone 1:276,277 synthesis of 1:276,277 Phase distribution techniques 7:488 Phase I trial 28:540 with monophosphoryl lipid A 28:540 Phase transfer catalysed oxidation 7:161,163 Phasecoside IV 25:97
619
Phaseic acid 6:559-562;27:346,350 formation of 27:346 isomerization rates of 27:350 Phaseogenin 25:97 Phaseolinone 6:555,556 synthesis of 6:556 X-ray crystallography of 6:555 Phaseollidin 20:496,497 Phaseollin 4:391,392 synthesis of 4:391,392 Phaseolus angularis 29:617,618 Phaseolus aureus 29:598 Phaseolus coccineus 25:93 Phaseolus lunatus 26:472;29:598 Phaseolus tribe 26:931 Phaseolus vulgaris 19:268;23:342; 25:489;26:1136;29:598 23-O-[3-D-glucopyranosyl-2-epi25-methyldolich-osteron from 18:495,522 cell suspension of 2:369 isozymes from 9:563 olean- 12-ene-type triterpene saponins from 21:659 Phaseoluteone 28:229 biological activity of 28:229 Phaseoside I 25:95,104 Phase-sensitive NOESY spectrum 26:12-14,29,34 ofbisdesmoside 26:41 ofdianchinenoside E 26:34 of mimusopin 26:14 of SAPO 30 26:41 of SAPO 50 26:41 of saponariosides C 26:12 ofvaccaroside D 26:29 Phaseside III 25:97 Phase-transfer conditions 6:326,327, 330,332;19:277,279 Phase-transfer reaction 19:231 catalyzed by 19:100 Phasianus colchius 5:836 hemoglobin components of 5:836 Phegmacine B2 22:580 Pheidole pallida (minors) 5:235,236, 254 2,5-dimethyl-3-ethyl-pyrazines of 5:222
Phelgmacine A2 22:580 (-)-c~-Phellandren-8-ol 11:307,308 a-Phellandrene 21:582,594;29:83 activity in AM assay system 29:83 [3-Phellandrene 7:100,101 ;21:582,594; 27:372 (-)-c~-Phellandrene 27:379 (+)-~-Phellandrene 27:379 Phellibiline 3:256 Phelline comosa 3:484 Phelline spp. 3:456 Phellinus genus 19:351 Phellinus tremulae 19:171 Phenalenone 26:474 Phenanthrene 25:542 based PKA inhibitor 25:542 Phenanthrene annulated 8hydroxyindolizidine 12:300 Phenanthrene ring enlargement 29:374 in allocolchicinoids total synthesis 29:374 9-Phenanthrenemethanol halofantrine chloroqvine 26:782,820,825,836 Phenanthrenes 20:280 Phenanthridines 4:542 from anils 4:542 Phenanthroindolizidine alkaloids 12:300 from Tylophora hirsuta 12:300 Phenazine- 1-carboxylic acid 21:186 Phendoxidase 25:719 (R)-ct-Phenethylamine 10:31 (S)-c~-Phenethylamine 10:31 Phenethylisoquinoline derivative 6:487 Phenidone 9:579;22:126 Phenobarbitol 25:66;24:218 Phenobarbitol induced hepatic tumors 25:46 Phenobarbitone 22:507 Phenol oxidase systems 16:584 in plants 16:584 Phenol/formaldehyde resins 9:330 Phenolase 25:654 Phenolic antioxidant activity 23:766, 767 methods for evaluation of 23:766 substrates used in 23:767
620
Phenolic cinnamic acid derivatives 9:219,220 Phenolic components 17:455;25:668; 27:483,836,853 ;28:200 bioactivity of 25:668 kuwanon G as 28:200 of Morus alba 17:455 Phenolic coupling reactions 16:504 Phenolic ellagic acid 25:543,546 Phenolic glycosides 27:687 Phenolic linear diarylheptanoids 26:885-894,905 Phenolic lipids 17:645;30:111,139, 150-176 bioactive 30:111 biological properties of 30:150-176 biosynthesis of 9:341,342 non-isoprenoid 9:313-362 occurrence of 30:111 separation of 30:139 structural elucidation of 30:139 synthesis of 9:343-369; 30:139-150 utilisation of 9:369-372 Phenolic triterpenes 7:150-152;30:674, 679,691 against HT-29 (human colon carcinoma) 30:691 against MEL-28 (human melanoma) 30:691 against P-388 (mouse lymphoma) 30:691 against A-549 (human lung carcinoma) 30:691 biogenesis of 7:150-152 from Kokoona zeylanica 7:147-149 Phenolic (x-diazoketone 6:60,61 bromochammigrene from 6:60, 61 spiroannulation of 6:60,61 Phenolics 17:444;24:503-509 170-NMR 17:586 as antiviral compound 24:503-509 in adventitious root cultures 17:444 in hairy root cultures 17:444
Phenols 17:586;27:702,703;24:297302;30:724 as antioxidants 30:724 as aromatizers 30:724 as colouring agents 30:724 as flavourings agents 30:724 as secondary metabolites 30:724 anodic oxidation of 8:159-172 chemoselective protection of 19:304 chromanes from 4:394 oxidation with TI (03)3 (TTN) 8:166,169 from olive oil 27:703 in the food industry 30:724 oxy-functionalization of 27:749 pharmaceutical interest 30:724 photosenstized oxygenation of 16:582 Phenol-sulfuric acid method 25:435 Phenoxazinone 26:965,1009,1014 Phenoxazone 26:493 Phenoxychromones 7:220 from Artemisia capillaris 7:220 Phenoxyl groups 16:611 quenchers of 16:611 Phensulfinylation 19:470 Phenyalkylamines 25:534 verapamil 25:534 N -Phenyl- [3-naphthylamine 26:359 Phenyl-4,6-di-O-benzyl-2,3-dideoxy-Derythro-hex-2-enopyranoside 10:354 et-C-glycopyranoside from 10:354 [3-C-glycopyranoside from 10:354 Phenyl 4-deoxy-[5-D-xylo-hexopyranoside 14:148 Phenylalanine 7:111 Phenyl cyclohexyl selenoxide 9:120, 121 Phenyl cyclohexyl sulphones 9:118,119 338 (NMR) of 9:118,119 Phenyl cyclohexyl telluride 9:123,124 ~25TeNMR of 9:123,124 3-Phenyl derivatives 27:841 [3-Phenyl glucoside 16:589 coupling of 16:595
621
Phenyl glucosides 17:437 Phenyl propanoids 24:503-509;27:768 as antiviral compound 24:503-509 ~x-Phenyl selenide 6:16 in [3-dictyopterol precursor synthesis 6:16 Phenyl sulfone derivative 30:486 dehydration of 30:486 hydrogenation of 30:486 synthesis of 30:486 vic-Phenyl thiobenzoate 6:541-542 metal reduction of 6:541-542 Phenyl thiogalactoside 7:48 Phenyl [3-D-galactopyranoside 8:315 4-Phenyl- 1,2,4-triazoline 3,5-dione (PTAD) 11:388-393 1-Phenyl-2-buten- 1-one 3:129 reaction with silyl enol ether 3:129 2-Phenyl-2-methylseleno-6-bromo heptane 8:6 1-Phenyl-2-nitroethane 19:118 3-Phenyl-3,4-dihydroisocoumarins 15:387 Phenylacetaldehyde 6:312;28:406 acaricidal properties of 28:406 synthesis of 6:312 Phenylacetic acid derivatives 6:320-322 synthesis of 6:320-322 Phenylacetonitrile 28:406 acaricidal properties of 28:406 2-Phenylacetyl-13-carbolines (R,S and T) 25:782 Phenylalanine ammonia-lyase 26:938 Phenylalanine 11:204,206 hyoscyamine from 11:204,206 scopolamine from 11:204,206 synthesis of 11:417,418 L- [U-C 14]Phenylalanine 15:347 L-Phenylalanine 5:467,470,474;19:323; 21:218,728 Phenylalanine 22:255;25:652,653,660, 928 Phenylalanine hydrolases 25:718 Phenylalanine lyase 7:111
(2S,3S)-Phenylalanine-3-d- 11:417,418 from (S)-pinanediol phenyl boronate 11:417,418 (S)- (x-Phenylamine 19:18 as a chiral auxiliary 19:18 Phenylation 19:497 of aldehyde 19:497 chemoselective 19:497 24-R-Phenylbrassinolide 19:477 23-Phenylbrassinosteroid 19:277-278 y-Phenylbutyrophenone 14:648 2-Phenylchromone 22:457 3-Phenylcyclohexanone 12:25 sulfenylation of 12:25 10-Phenylcytochalasins 15:353 4a-Phenyldecahydroisquinoline 12:458 3-Phenyldihydroisocoumarins 15:387 Phenyldizene 9:581 o-Phenylene phosphorochloridate 8:74 o-Phenylenedimethanol 11:130,131 ketal of 11:130,131 Phenylephrine-induced vasoconstriction 30:72,73,75 effect of nitric oxide (NO) synthetase 30:73 effect ofxanthoangelol 30:74 effect ofxanthoangelol E 30:74 Phenylethanal 30:215 reaction of 30:215 (R)-Phenylethanoid glycosides (1,7bis(3,4-dihydroxyphenyl)heptan-3ol) 25:543 Phenylethanoids 25:465;26:330 antimicrobial activity of 26:330 2-Phenylethanol 7:104,105,111,112,125 (S)- 1-Phenylethylamine 13:485 Phenylethylamine 25:538 (S)-(-)-2-Phenylethylamine 8:300 X-ray crystallography of 8:300 (S)-2-Phenylethylamine 8:301 (S)- 1-Phenylethylamines 14:555,556 (R)- 1-Phenylethylamines 14:555,556 piperidine derivative from 14:555,556 pyrrolidine derivative from 14:555 pyrrolidone derivative from 14:560,561 N-(R)- 1-Phenylethylcarbamates 18:427
622
(S)- 1-Phenylethylglutarimide 13:477 (R)-Phenylethylisocyanate 13:324,325 9-Phenylfluoren-2-yl amine 12:338 (-)-Phenylglycinol 14:744 condensation of 14:744 with glutaric dialdehyde 14:744 Phenylglycinol 19:311 (R)-Phenylglycinol 19:38 bis-Phenylhydrazine 12:377,378 into N-methylarcyriaflavin A 12:337,338 Phenylhydrazine 9:581 autoxidation of 9:581 1,2-bis-Phenylhydrazone 12:377 Fischer indolization of 12:377 Phenyliodosyl bis (trifluoroacetate) 21:391 Phenylisothiocynate 25:435 Phenylketonuria 30:374 autistic features in 30:374 Phenyllactate 12:223,225 synthesis of 12:223,225 [3-Phenyllactic acid 26:592 Phenyllactic acid 22:728;30:216 conversion of 30:216 Phenyllactoyl-CoA 22:728 Phenyllanine hydroxycinnamate 25:652 8-Phenylmenthol 13:76 (-)-8-Phenylmenthyl 19:14 8-Phenylmenthyl ester 13:74,76 (-)-Phenylmenthyl ester of methylmalonic acid 10:411 asymmetric alkylation of 10:411 8-Phenylmenthylglyoxalates 18:190 2-Phenylnaphthalene 30:214 C-condensation of 30:214 from arylethanals 30:214 mechanism of formation of 30:214 9-Phenylphenalenones 17:372 Phenylpolysiloxane 9:457 Phenylpropanes 22:644 Phenylpropanoid 25:541,543,651 curcumin 25:543 Phenylpropanoid alkaloids 25:540 D-cathinone 25:531 D-cathine 25:531 L-ephedrine 25:531 pseudoephedrine 25:531
Phenylpropanoid compounds 25:651, 659 Phenylpropanoid derivatives 28:403 acaricidal activity of 28:403 Phenylpropanoid moieties 27:853 Phenylpropanoid pathway 26:154 Phenylpropanoid wood 20:613 Phenylpropanoids 5:419,420,426,427; 15:29;24:228-232,302,799,845-847, 849 biological activity of 5:505 Phenylpropargylic ethers 4:368,369 chromenes from 4:368,369 Phenyl-pyrrole analogues 29:406 rhazinilam synthesis of 29:406 Phenylpyruvic acid 22:728 N-Phenylquinoneimine 26:976 trans- 5 -P hen yl-se l eno-4-me tho x y
derivatives 12:418,419 as 2-amino alcohol synthon 12:418,419 Phenylselenyl alkanes 9:119 77Se-NMR of 9:119 Phenylselenyl bromide 14:737 in quinolizidine formation 14:737 Phenylselenyl chloride 6:426-428 cyclofunctionalization with 6:426-428 Phenylselenyl cyclohexane 9:119-120 77Se-NMR of 9:119-120 o~-Phenylselenyl ester 21:387 Phenylselenylation 1:242,248 Phenylserine 30:216 conversion of 30:216 Phenylsulfone derivatives 30:488 synthesis of 30:488 1-(Phenylsulfonyl) indole 6:509,510 regiospecific lithiation of 6:509, 510 (E)-bis(Phenylsulfonyl)ethylene 19:6 2-Phenylsulfonyl-l,3-dienes 21:379 Phenylthio ester 13:506 zirconium enolate of 13:506 2-Phenylthio glucals 10:346 by direct lithiation 10:346 Phenylthiohydantoin (PTH) derivative 2:33 phorbol 2:261
623
3-(Phenylthiomethyl) camphor 4:763, 764 4,5-trans and 4,5-cis-5-Phenylthiooxazolidin-2-ones 12:481 5-Phenylthiooxazolidin-2-ones 12:481 N-Phenyltrifluoromethanesulphonimide 20:581 N -Phenyl-c~-naphthylamine 26:359 Phenyl-[3-D-glucopyranoside derivatives 7:55,56 kinetic parameters of 7:55,56 a-Phenyl-~,-lactone derivative 10:410, 411 alkylation of 10:410,411 stereoselective 10:410,411 Phenytoin 22:507 Pheochromocytoma 26:927 Pheomelanins 26:1018 Pheophytin 25:691 Pheromonal function 6:458 Pheromonal specificity 7:6 Pheromone 16:138 of California red scale 16:138 Pheromone activity 7:6 Pheromones 1:276,389,682-684,695; 7:193 ;16:138;19:122;28:428 against Tetranychus mites 28:428 farnesol as 28:428 fire ant 1:682,683 from Pharoah ants 1:389;4:606 macrocyclic 8:219 naphthoquinones as 28:428 nerolidol as 28:428 of california red scale 16:138 of cigaratte beetle 1:695 of Vespa orientalis 1:684 oriental hornet 1:684 structure of 28:428 Phidolopora pacifica 17:92 Philanthotoxins 21:70 Philanthus triangulum 5:223,224,231, 251,253 Phillygenin 5:489-491,522;26:237,241 as PAF-induced inhibitor 26:241 Phillygenin 4-O-glucoside 5:476,490 Phillyrea latifolia L. 29:685 Phillyrin 26:201
Philodendron scandens 9:317,321 Phleba strigosozonata 29:296 Phlebia radiata 26:1013 Phlebotomus 26:783 Phleum pratense L. 27:217 9'-O-(-)-Phlligenin 26:255 Phloeodictine B 25:829 Phloeodictine C12 25:829 Phloeodictines 25:829 Phloeodictyon 25:829;28:688 Phlomis aurea 30:265 apigenin 7-glucoside from 30:265 Phlomis betonicoides 1:666;15:20; 27:14,24 baiyunoside from 27:14,25 phlomisoside I from 27:14,25 Phlomis medicinalis 25:251 Phlomis mendocina 25:133 Phlomis spectabilis 30:265 Phlomis younghusbandii 25:257 Phlomisflavoside A 30:294 structure of 30:294 Phlomisflavoside B 30:294 structure of 30:294 Phlomisoside I 15:20;27:14,25 structure of 27:25 Phlomisoside II 15:20 Phlomosides 25:251 Phloretin (2',4,4',6'-tetrahydroxydihydrochalcone) 29:577 effects on aminopeptidase N 29:577 Phloretin (2',4,4', 6'-tetrahydroxydihydrochalcone) 29:577 from aglycone 29:577 Phloretin (dihydrochalcone) 29:582 effects on MMP 29:582 Phloridzin 21:520,522 Phlorizidin 26:800,801 Phlorizin 27:17,33,34 structure of 27:34 Phloroacetophenone 9:341 Phloroglucinol 4:391;9:328,329,341; 13:355-359;21:520,522,542 Phloroglucinol derivatives 30:629 antimicrobial activity of 30:629 Phloroglucinols 22:644,650,656; 30:610,629
624
antimicrobial activity 30:629 Phlorotannins 21:520 Phocomelia 7:10,21 Phoenix canariensis 27:840 Phoenix dactylifera 18:507 Phoenix paludosa 7:189 Phoenix reclinata 22:529 for epilepsy 22:529 Phogostimulants 23:643 Pholacantha synonyma 10:320 Pholagacanthus thyrsiflorus 25:251 Phoma betae 4:601 Phoma destructiva 6:555 Phoma exigna var. indoxi dabilis 6:555 Phoma sorghina 28:114 Phoma sp. 22:251,253;25:691;28:122 Phomactins 24:1062 biological activities of 24:1062 Phomasetin 28:122 as HIV inhibitor 28:122 Phomenone 6:554-556 synthesis of 6:556 (+)-Phomenone 6:555 synthesis of 6:555 Phomis 26:172 Phomolactone 15:350,351 Phomopsin-A 25:886 Phomopsis 9:203 Phomopsis citri 15:341 Phomopsis convolvulus 15:341-345 Phomopsis foeniculi 26:1128 Phomopsis helianthi 15:341,345,346 Phomopsisjuniperovora 15:346 Phomopsis leptostromiformis 15:341, 347 Phomopsis longicolla 15:341 Phomopsis oblonga 15:383,388-392; 21:207 5-methylmellein from 15:385 nectriapyrone from 21:207 Phomopsis paspalli 15:341,352 Phomopsis viticola 15:341 Phomosin 15:346 Phoracantha synonyma 6:542;8:222 macrocycles from 8:221 (+)-Phoracantholide 19:154 isolation of 19:154 Phoracantholide I 8:222
(-)-Phoracantholide I 10:320-323 synthesis of 10:320-323 Phoracantholide J 8:222 Phoracantholide K 8:222 Phoracantholide M 8:222 Phoracantholide O 8:222 from Phoracantha synonyma 8:222 Phoracantholides 8:222,242 Phoracantholides I,J,K,M,O 8:222 Phorbas sp. 19:601;25:759 Phorbol 1:546,547,20:19;25:242 synthesis of 12:245-272 total synthesis of 12:265-272 Phorbol 12-myristate fl-acetate 25:598 Phorbol 12-mysristate- 13-acetate 25:488,937,948 Phorbol ester 25:726 Phorbol ester promotors 25:66 Phorbol ester-induced activation 12:389 inhibition of 12:389 Phorbol esters 10:4;25:243,246,524, 536,542,543 ;27:830;30:593 in tumor-promotion 30:593 Phorbol mimic 12:264 intramolecular 12:264 from fulvene 12:264 stereoselective 12:264 synthesis of 12:264 Phorbol myristate acetate (PMA) 12:245 ;23:474 ;30:70 Phospho enol pyruvate (PEP) 23:82,741 Physcion 23:797 Phytohemagglutinin (PHA) 23:474 Pichilan 23:115 Phorbol- 12,13-dibutyrate 25:542; 27:831 Phorbol- 12-myristate- 13-acetate (PMA) 25:242 Phorbolbased pKC activators 25:524 Phorboxazole A 19:600 antifungal activity of 19:600 Phorboxazoles 25:756 Phorboxazoles A & B 25:759,760 Phormidium autumnale 26:358 Phormidium bohneri 26:365 Phormidium sp. 26:364 Phormidium tenue 25:868
625
Phosgene 12:113 isocyanides from 12:113 Phosphaheterocyclics 9:509-528 bis-Phosphaneoxide 9:527 Phosphatase 14:304 Phosphate 27:872 hydrolysis of 27:872 Phosphate acceptor 27:822 Phosphate buffered saline 25:434 Phosphate derivatives 4:231 antileukemic activity of 4:231 antivirus activity of 4:231 of 2,4-pyrimidinedione 4:231 Phosphate protecting groups 4:285 Phosphatidyliserine 22:35;25:938 Phosphatidyl inositol phosphateactivated protein kinase 25:522,547 Phosphatidyl inositol-3,4,5-triphosphate (PIP3) 25:522,547 Phosphatidyl inositol-3,4-kinase (PIP2) 25:522,547 Phosphatidyl inositol-3-kinase (P13K) 25:522,525 Phosphatidylinositol 15:441;25:475,487 L-a-Phosphatidylcholine 25:333 Phosphatidylcholine 9:565;30:79,103 Phosphatidylcholine vesicles 18:848, 856 L-a-Phosphatidylethanolamine 25:333 Phosphatidylinositol 3-kinase 18:394; 27:843 Pho sphatidylino sito 1 -4,5-b ipho sphate (IP3) 25:521 Phosphatidylinositol cycle 25:483,494 Phosphatidylinositol kinases 27:842 Phosphatidylinositol phosphateactivated proteins 25:517 Phosphatidylinositol turnover 15:452 Phosphatidylinositol-3,4,5-trisphosphate 18:410,427;25:516,517;27:828 Phosphatidylinositols 18:445-450 synthesis of 18:445-450 Phosphatidyl-myo-inosito 1-4,5bisphosphate 18:392 L-a-Phosphatidy-L-serine 25:333 5-Phosphino-aldopyranoses 6:366-375 Phosphino-aldoses 6:360-365 5-Phosphino-aldoses 6:365,366 6-Phosphino-aldoses 6:375,376
Phosphinothricin 6:352 4-Phosphinyl aldoses 6:360-365 7-Phosphinyl-aldoctanose 6:377 4-Phosphinyl-aldofuranoses 6:360-365 5-Phosphinyl-aldopyranoses 6:366-375 6-Phosphinyl-aldoseptanose 6:377 from 6-deoxy-6 [(ethoxy), alkyphos-phinyl]-Dglucopyranose 6:377 1-Phosphinyl-aldoses 6:353-356 2-Phosphinyl-aldoses 6:357,358 3-Phosphinyl-aldoses 6:359,360 5-Phosphinyl-aldoses 6:365,366 6-Phosphinyl-aldoses 6:375,376 1-Phosphinyl-ketoses 6:353-356 Phosphinyl-L-fucosamine analogs 6:369 Phosphite method 4:271-274,280 for oligonucleotide synthesis 4:271-274,280 in oligoribonucleotide synthesis 4:303 mechanism of 4:272 oxidation reaction 4:280 Phosphitylating agents 4:272,273; 13:276 Phosphitylation 8:388,389 2',5' -Phosphodiester 14:283 antiviral activity of 14:283 cyclic 14:283 synthesis of 14:283 Phosphodiester method 4:267 for oligonucleotide synthesis 4:267 Phosphodiesterase (PDE) 5:512;12:399; 13:288;25:507,597 Phosphodiesterase (PDE) inhibitor 25:275,488 Phosphoelnolpyruvate-dependent aldolases 30:424 structure of 30:424 Phosphoenol pyruvate (PEP) 11:182 Phosphoenol pyruvate carboxykinase 25:523 Phosphoenol pyruvate synthetase 11:182,208,209 (Z)-[3-3H]Phosphoenolpyruvate 11:183, 184 Phosphoenolpyruvate (PEP) 21:304; 30:423,429,425
626
irreversible aldol reaction of 30:429 irreversible condensation of 30:425 synthesis of 30:423 Phosphofructokinase 7:387 Phosphogalactomannan 5:299 6-Phosphogluconic acid 25:670 6-Phosphogluconic dehydrogenase 25:670 Phosphoglycerate 21:304 Phosphoglyceric acid 11:208 Phosphoglycogen synthase 25:525 Phospholipase 21:5,50;22:308 Phospholipase A2 12:397;22:21,112, 616,629;25:263,270,374,688,734, 842,867,903 Phospholipase A2 inhibitor 25:47,593 Phospholipase B 25:333 Phospholipase C (PLC) 15:448;22:19, 21,25 ;25:521,522,530,548,696 Phospholipase C-y (PLCy) 25:545 Phospholiphase A2 21:252 Phospholipid bilayer 18:848 Phospholipids 12:233;17:644;24:521, 522 as antiviral compound 24:521, 522 Phosphomannans 5:280 O-Phosphomannans 5:284,285 Phosphomannomutase 26:1140 Phosphomolybdic acid 22:108 Phosphomonoester formation 4:285 phospate protecting groups for 4:285 3-Phosphomonoesterase 12:399 staurosporine effect on 12:399 Phosphonate condensation 19:83 Phosphoniosilylation 3:79,80 of enones 3:79,80 Phosphonium mercaptides 4:554 Phosphonium ylides 4:553-578 acylation with thioesters 4:554 acylation with trimethylsily esters 4:564 oxidation 4:553,558 Phosphopolyprenols 8:100-103 biosynthesis of 8:100-103 glycosyl esters of 8:63
Phosphoprotein (P-Pr) 25:522,548 Phosphoprotein phosphatases (PPs) 25:517,521 Phosphoramidate linkage 4:293 stability of 4:293 Phosphoramidates 13:273,274 Phosphoramidite 4:306;8:373;13:265, 267,268,269,270;18:398 in coupling reactions 4:306 synthesis of 8:388-390 Phosphoramidite cycle 13:268 Phosphoramidite method 13:270 methylphosphonates by 13:270 Phosphoramidites 8:373;13:265,267, 268,269,270;18:398 synthesis of 8:388-390 Phosphoribosyl pyrophosphate aminotransferase 7:387 ortho-Phosphoric acid 27:820 Phosphoric acid 8:63;21:357 diesters of 8:63 Phosphorodichloridate 8:83 Phosphorodithioates 13:268,269,270, 271,274 from thiophosphoramidites 13:272,273 Phosphoroimidazolidate 8:90 Phosphorothioates 13:263,268,269 diastereoselective synthesis of 13:276 Phosphorus analogs 6:352,355,357,358 of D-arabinitol 6:355 of D-arabinofuranose 6:352,355 of D-furctofuranose 6:352,355, 357,358 of D-fructose 6:355 of D-glucopyranose 6:352,355, 370,373,376 of D-gycitol 6:355 of D-mannofuranose 6:355 of D-ribofuranoses 6:352,355, 359,363,364 Phosphorus oxychloride 8:72,73 with diisopropylamine 12:113 5'-Phosphoryl oligonucleotides 4:286, 288,294,294 synthesis of 4:286,288,294,294 Phosphorylase kinase 25:264;27:852 activity of 27:852
627
Phosphorylases 7:35 3'-Phosphorylated adenosine derivative 14:288 2'-Phosphorylated diribonucleotides 14:308,309 by calf intestinal alkaline phosphatase 14:308,309 dephosphorylation of 14:308,309 2-Phosphorylated oligoribonucleotides 14:688-696 synthesis of 14:688-696 Phosphorylated phsophotidylinositol 25:487,488 Phosphorylated RNAs 14:308,3092[A(2'-p)pA(2'-p)pU] 14:308,309 synthesis of 14:308,309 Phosphorylation 30:808 of G-coupled proteins 30:808 Phosphorylation 8:97,100;9:391; 12:384;18:395,397-402;30:808 methylphosphonates by 13:272 of alcohols 8:80 of citronellol 8:76 of E-geraniol 8:76 of G-coupled proteins 30:808 ofmevalonic acid 7:322 of prenols 8:75,80 with dihydrogen phosphate 8:105 Phosphoserine 25:517 Phosphothreonine 25:517 Phosphotriester method 4:268-271, 301-303 ;13:271,272 for oligodeoxyribonucleotides synthesis 4:268-271,301-303 in oligoribonucleotide synthesis 4:301-303 methylphosphonates by 13:272 reaction mechanism 4:270 using polymer support 4:271 Phosphotriesters 13:263,271 synthesis of 13:272 Phosphotyrosine binding SH2 domains 25:525 2-Phospinyl-ketoses 6:357,358 Photoaddition 3:102,103;24:201 Photoaffinity probes 27:330 Photoautotrophic cell lines 7:9 N-phthalylaspartic acid 7:10
Photobacterium damsela 25:719
Photochemical hydrolysis 6:331,333 Photochemical [2+2] cycloaddition 1:548 Photochemical acyl migration 1:51 Photochemical annulation 6:48 in (+)-Ag(12)-capnellene synthesis 6:48 of 13-diketone 6:48 Photochemical decarboxylation 3:487 ofallylic carboxyls 3:487 Photochemical olefin isomerization 1:413,414 Photochemical oxidation 1:159 Photochemical reaction 6:330,331 Photochemical rearrangement 1:547; 14:356-360 Photochemical synthesis 20:302,303 Photochemical transformation 1:218, 219 of protoberberine 1:218,219 of spirobenzylisoquinoline 1:218,219 Photochemical valence isomerization 1:189 Photocyclization 1:45,52,63,141; 3:14-17,19,20,309,414;14:65;16:32; 24:759,760 of oxopropyl ester 8:131 ofphenacyl ester 8:133 non-oxidative 3:403-406 of enamides 3:401-403 reductive 3:402,407,407-410,414 Photocycloaddition 11:20;16:651 [2+2]-Photocycloaddition 3:97;6:39; 8:251 ;10:405,406;16:264 diastereoselective 14:502 of cyclic enones 14:502 with chiral a,~-unsaturated acetals 14:502 [6rt+2rt]Photocycloadditions intramolecular 1:568,569 ofalkenyltropones 1:568,569 Photocytotoxic action 30:315 ofhypericin 30:315 Photodeoxygenation 3:199 Photodermatosis 30:607 of hypericism 30:607
628
Photodiode array detection 9:462 Photodynamic activity 23:361 of coumarin 23:335,356,357, 353,368,376,393,550,553 Photo-Fries rearrangement 499 Photo-induced annulation 12:293 of N-alkylated pyrrolidinones 12:293 Photo-induced deazetation 22:205 Photo-induced deoxygenation process 14:166 Photoinduced electron transfer 30:540 in [3-carotene 30:540 in canthaxanthin 30:540 Photo-induced electron-transfer 14:166 Photo-induced reduction 14:166,167 of esters 14:166,167 Photo-initiated radical allylation 12:487 Photoisomerization 12:236 of 3-oxo-4,5-oxido steroids 12:236 of ABA 27:354 cis, trans-Photoisomerization 27:355 Photolactone 8:134 Photolithography 13:646 Photolysis 6:475,476 of (+)-laudanosine methiodide 6:475,476 of (-)-orientalinone 16:512 of (4-oxopentyl)D-glycoside 10:420 of carbohydrate derivatives 14:649,650 of enamine 16:469 of N-alkenylbenzotriazoles 13:445,446 of nitrone 6:474,477 of phthalimide derivatives 14:649,650 of trans-canadine N-oxide 6:474 of [3-ketoester 14:652 Photo-oxidation 6:472,491,492;16:604; 30:443 role in aldol reaction 30:443 Photo-oxygenation 1:190,214; 4:419-421,424;14:597,601
of coptisine 1:191 of palmatine 1:191 ofprotoberberine 1:203 Photophosphorylation 21:98 Photopyridone 10:618,619 from pyridone 10:618,619 Photorearrangement 16:512 Photoreduction 1:257 intramolecular 1:257 Photosensitized oxidation 6:138,142 Photosensitizers 30:607 hypericism as 30:607 Photosensitizing activity 23:353 of coumarin 23:335,356,357, 353,368,376,393,550,553 Photosolvolysis 6:475,476 of 2,5-benzoxazonine 6:475,476 ring destruction by 6:475,476 Photosolvolytic reactions 6:472,475, 477,484 Photosynthesis 30:521,762 Photosystem 30:537 cation radicals in 30:537 Phototoxic 17:378 Phragmalin derivative 9:105 Phryma leptostachya 26:231 (+)-haedoxan A from 26:231 (+)-haedoxan D from 26:231 (-)-haedoxan D from 26:231 Phthalic acid 17:441 Phthalide annelation 4:322,341 Phthalide isoquinoline alkaloids (+) bicculine 25:528 bicuculline 25:532 N-methyl bicuculline 25:528 narcotoline 25:533 norbicuculline 25:537 a-narcotine 25:533 tetrahydropapaveroline 25:533 Phthalideisoquinoline alkaloids 1:187, 189;21:69 Phthalideisoquinoline alkaloids Phthalimides 26:1161 N-Phthalylglutamic acid 7:9 thalidomide from 7:9 N-Phthalyl-L-glutamic acid 7:10 S-thalidomide from 7:10 Phthoramycin 5:607-609 Phloretin 21:520,522;22:458
629
Phycobiliproteins 26:376 fl-Phycoerythrin 22:317
Phycomyces blakeslearus 18:806; 25:318 (15Z)-phytoene from 7:327 Phycomyces sp. 5:276,294 Phycomycetes 22:460 Phycopsis terpnis 25:858 Phyllacton I 25:695 Phyllacton H 25:695 Phyllamycin B 26:196 Phyllamyricin E 26:194 Phyllamyricoside A 26:196 Phyllanthin 26:237 Phyllanthocin 8:281 synthesis of 8:281 (+)-Phyllanthocindiol 16:255 synthesis of 16:255 Phyllanthostatin A 26:196 Phyllanthus 29:572 Phyllanthus acuminatus 26:211 phyllanthostatin A from 26:211 Phyllanthus amarus 26:117;27:840; 29:572 activity of 27:840 phypophyllanthin from 26:217 phyllanthin from 26:217 Phyllanthus emblica 29:587 Phyllanthus emblicata L. 22:529 for epilepsy and convulsions 22:529 Phyllanthus genus 30:207,208 analgesic effect of 30:208 in treatment of hepatitis 30:207 use in kidney disturbances 30:207 use in urinary lithiasis 30:207 use in folk medicine 30:207 Phyllanthus myrtifolius 26:225 phyllamyricin E from 26:225 phyllamycin B from 26:225 phyllamyricoside A from 26:225 retrojusticidin B from 26:225 Phyllanthus niruri 5:49;17:317,343, 421,441,443 ;26:233,237 hyophyllanthin from 26:233 hypophyllanthin from 26:237 nirtetralin from 26:237 phyllanthin from 26:237
Phyllanthus urinaria L. 22:529 for epilepsy and convulsions in children 22:529 Phyllantin 26:191 Phyllantoside 14:519 Phyllatocin 19:128 Phyllida varicosa 21:364,366 Phyllidia bourguini 17:16 Phyllidia ocellata 25:858 Phyllidia pustulosa 21:358,359,360, 361,366;25:852;28:651 4~-isothiocyanogorgon- 11-ene from 28:651 Phyllidia sp. 6:80 2-isocyanopupukeanene from 6:80 Phyllidia varicosa 6:79,17:15 2-isocyanopupukeanene from 6:79 Phyllidiidae 17:15 Phyllirin 26:237 Phyllocladus trichomanoides 27:838 Phyllocoptruta oleivora 28:423 Phyllodulcin 15:5;27:7,5,17 from Hydrangea macrophylla 13:660;15:30 from Melaleuca leucadendron 15:387 of stevioside 27:5 structure of 27:7 thaumatin 27:5 Phyllomedusa sauvagii 23:341
Phytophthora megasperma 23:138
Phytophthora parasitica 23:115,133 Phyllomedusin 27:800 Phylloquinone 25:236;30:304 as primary metabolites 30:304 Phyllospongia foliascens 28:709 in serological reactions 28:709 sulfated galactolipid M-6 from 28:709 Phyllospongia sp. 25:695 Phyllostachys nigra Lodd 22:529 for convulsions in children 22:529 Phyllostachysin A 15:163-165,167 13C-NMR of 15:165
630
from Rabdosia phyllostachys 15:174 IH-NMR of 15:164 Phyllostachysin B 15:118 13C-NMR of 15:132 from Rabdosia phyllostachys 15:174 1H-NMR of 15:125 Phyllostine 4:610,611 synthesis by retro-Diels-Alder reaction 4:610,611 Phylum chordata 28:621 Physagulin C 20:180,242 Physagulins E 20:194 from Physalis angulaten 20:194 Physagulins G 20:194 from Physalis angulaten 20:194 Physalaemin 27:800 Physalin 20:247 Physalin A 20:182 from Physalis angulaten 20:182 Physalin B 20:183-189,234 from Physalis alkekengi 20:182 Physalin C 20:182 from Physalis alkekengi 20:182 from Physalis minima 20:234 Physalin D 20:182,238 from Physalis minima 20:234 Physalin F 20:182 from Physalis minima 20:234 Physalin G 20:182 Physalin H 20:182 Physalin I 20:182 Physalin J 20:182 Physalin K 20:182 Physalin L 20:189 Physalin N 20:189 Physalin O 20:189 Physalindicanol A 20:238 Physalindicanol B 20:238 Physalis acnes 20:32 Physalis alkekengi 20:182,189,191,247; 22:729,740 physalin A from 20:182 physalin B from 20:182 physalin C from 20:182 physalin L from 20:189 physagulius E from 20:194
physagulins G from 20:194 zeaxanthin from 7:360 Physalis angulata 20:180,182,194,247 Physalis berghei 20:522,524 Physalis cordeana 20:470 Physalis cubeba 20:619 Physalis lancifolia 20:182 Physalis minima 20:234,238,247 A4,6-hydroxyphysalin from 20:189 Physalis mirabilis 20:859 Physalis peruviana 20:247 Physalis pubescens 20:180,189,191,247 physapubescin from 20:189 physapubenolide from 20:189 pubescenin from 20:191 Physalis vulgaris 20:845,849,851,853, 854,857 Physalis yoelii 20:521 Physalolactone 20:246 Physalolactone B-3-O-[3-(D)glucopyranoside 20:191 from Physalis peruviana 20:191 Physangulide 20:246 Physapubenolide 20:180,191,242 from Physalis pubescens 20:189 Physapubescin 20:180,189,191,224, 224,242 from Physalis pubeseens 20:189 Physarium sp. 5:275 Physarum polycephalum 5:275,276; 28:133;29:23 ;223,239;29:239 all-trans-N-[ 11-(2-acetylamino3-hydroxyphenyl)2,4,6,8,10undecapentaenoyl]-S-glutamine from 29:240 as myxoamoebae 29:243 chemical constituents of 29:239 chrysophysarin A from 29:242 constituents of 29:243 cultivation of 29:247 DNA polymerase activity of 29:244 isomers of 29:245 lysophosphatidic acid from 29:243 metabolites of 29:242 pigments of 29:241 plasmodial constituents of
631
29:239 polycephalins from 29:242 spore germination by 29:250 sterol contents of 29:240,243 synthetic derivatives of 5:246 Physcicon 22:608,609,610,617,618,619, 620 Physcicon-8-O-fl-D-glucoside 22:617, 618 Physical properties 18:844-848 of lipo-gastrin 18:844-848 of lipo-CCK 18:844-848 Physicon-8-D-glucoside 22:609,610 Physiological activities 21:373 Physiological effects 26:207;30:192 of COX- 1 enzyme 30:192 of phytoestrogens 26:207 Physiological function 30:637,799 of opioid system 30:799 of triterpenes 30:637 Physiological properties 4:13 of galanthamine 4:13 of pretazetting 4:13 Physiological responses 21:98,109 (-)-Physostigmine 14:637;19:144-145; 22:29 for Alzheimer disease 14:637 from (-)-eserethole 14:637,638 synthesis of 14:636-638 Physostigmine 13:70,631 ;21:52,84, 102;22:17,736;25:536;26:838 as immunosuppressive drug 25:536 Physovenine 21:84;25:536 as immunosuppressive drug 25:536 Phytosterol 9:454 Phytoalexin rishitin 25:319 Phytoalexin synthesis 25:507 Phytoalexins 4:391,392;7:119,184; 9:221 ;13:637 ;25:484;26:468,472, 473,494,745,1289;27:60-62,498 antimicrobial properties of 16:564 from ethylene 27:60 from glycoproteins 27:60 fromjasmonic acid 27:60 by liberation of enzymes 27:61 oligopeptides as 27:60
oligosaccharides as 27:60 production of 16:573 reactive oxygen compounds (ROS) as 27:61 salicylic acid as 27:60 generation of 27:60,61 Phytoanticipin 25:294,321,662 Phytochemicals 21:457 as hypoglycemic agent 21:459, 488 Phytochrome 7:92 Phytochrome proteins 25:529 Phytoecdysone 25:55,59,546 Phytoecdysteroids 20:114;26:699;29:10 ajugalactone as 29:13 ajugasterone D as 29:13 biological data of 29:11 carthamosterone as 29:13 cyasterone as 29:13 identification of 29:10 mode of action of 29:14 novel modifications in 29:11 physicochemical data of 29:11 side-chain lactones in 29:11 sidisterones as 29:13 stachysterone D (shidasterone) as 29:13 structural diversity of 29:11,12 (15-Z)-Phytoene 7:325-326,329,335 from Phycomyces blakesteeanus 7:327 ( 15Z,9'Z)-phytofluene from 7:332 Phytoene 7:330-335,360;20:588,590; 26:299,300;30:519 desaturation reactions of 7:327-329 from geranylgeranyl diphosphate 7:321,322,325 from prephtoene diphosphate 7:325-327 geometrical isomers of 7:329 phytofiuene from 7:327-329 structure of 30:519 Phytoestrogens 26:207 physiological effects of 26:207 Phytofluene 7:330-335;20:588,590; 26:299,300;30:519
632
~-carotene from 7:327-329 from phytoene 7:327-329 structure of 30:519 (15Z,9Z)-Phytofluene 7:335 (9Z,9'Z)-~-carotene from 7:332 from (15Z)-phytoene 7:332 Phytoharmones 25:367 Phytohemaglutinin (PHA) 25:267 Phytohormones 8:115-135,227 Phytol 21:589;25:245 Phytolacca acinosa 7:144,145 triterpenoids of 7:144,145 Phytolacca americana 13:655 Phytolacca dodecandra 7:427,428,430, 434 ;21:660;28:400 tick toxicity of 28:400 Phytolaccagenin A 7:144,145 Phytolaccanol 7:144,145 Phytolysis 27:330 of bovine serum albumin 27:330 (All-E)-Phytone 7:325-325,327,329 from Mycobacterium sp. 7:327 Phytoparasitic nematodes 22:401; 26:427,428 Phyto-pathogenic oomycete 25:395 Phytopathogens 21:232 Phytophthora 25:303,395,396 Phytophthora cinnamomi 21:190,199, 223,233 Phytophthora elicitins 25:395 Phytophthora infestans 5:276;21:181; 26:936 Phytophthora megasperma 25:303,396 Phytophthora nicotianae var. parasitica 26:404,418 Phytophthora parasitica 5:607 Phytophthora sojae 22:498 Phytophthora sp. 5:276;7:183;9:203; 21:197,221 Phytopolysaccharide (PS) 30:401 inhibitors of 30:401 Phytoprotectants 25:320 Phytosphingolipids 18:457-490 synthesis of 18:457-490 biological activities of 18:459, 460 D-ribo-C~8-Phytosphingosine 18:471, 478,485 D-xylo-C~6-Phytosphingosine 18:479
D-ribo-Phytosphingosines 18:465 Phytosphingosines 5:709;18:786,806 Phytosterol esters 9:458 Phytosterolemia (lipid storage disease) 9:478 Phytosterols 18:520;22:482 Phytosulfokines 25:368,380 Phytosulfokines signal 25:379 Phytotherapeutic preparations 30:703 from plants 30:703 Phytotoxic activity 15:345;21:238-240; 22:626;26:452 Phytotoxins 6:554-556;15:342;17:475; 21:204;30:751 toxic effects of 30:751 Phytoxin pisatin 25:322 PI turnover inhibitors 15:452 biological activity of 15:461,462 PI-4, PIG, CDI homologue 29:591 effects on cathepsin D, trypsin 29:591 Pica pica 5:836 hemoglobin components of 5:836 Picea 27:372;29:589 Picea abies (L.) Karl. 1~;:498;25:666; 27:370,385 Picea cocos 29:99 Picea glehni 20 99,100 Picea sitchenes, 19:247 Piceantannol 9:391 ;22:630;25:541, 543,546 from Euphorbia lagascae 9:391 protein-tyrosine kinases (PTK) inhibition by 9:390,391 Piceid 22:609;26:530,571 cis-Piceid 22:611,619,621 Picha strasssburgensis 5:287 Pichia angusta 21:391 Pichia anomala IFM 47182 28:476 Pichia bovis 5:287 Pichia farinosa 5:283 Pichia ohmeri 5:283 Pichia pastoris 5:283;26:1263,1269, 1288 Pichia sp. 5:281,297 Pichia terricola 1:706 reduction with 1:706 Pichia totetana 5:283
633
Pichia vanro'i 5:283 Picicularia oryzae 5:287,598 Piclavine A 16:453 antibacterial activiy of 16:453 antifungal activity of 16:453 from Clavela picta 16:453 Picnomon acarna L. Cass. 22:529 Picomavirus 30:406 Picraline 5:125;9:183,184 Picrasane 11:71,73,96,105 Picrasidine F 1:126 (+)-Picrasin B 11:76,77 synthesis of 11:76,77 (+)-A2'3picrasin B 11:76,77 synthesis of 11:76,77 Picrasin-A 23:314 Picrasin-B 5:38-41;7:396 Picrasin-D 23:314 Picrasin-E 23:314 Picrasinol-C 23:314 Picrasinol-D 23:314 Picrasinoside A-G 7:384,385 Picrasma ailanthoides 7:369,385; 23:291 Picrasma quassioides 1:126;23:291 Picrocrocin 25:954;26:293,295,296, 298-300,303,306,307 Picrolemma pseudocoffea 7:369,381 Picromycin 5:615,616 Picronolide 5:615 13C-NMR spectrum of 5:39,40 IH-NMR spectrum of 5:41,41 Picropodophyllone 18:600;24:771; 26:193 Picropodophyllotoxin 26:166,193 Picrotoxin 22:508 Picrotoxinin 17:608;26:867,868 Pictet-Spengler condensation 1:72; 14:633 Pictet-Spengler cyclization 8:265,266, 288,289;19:301 ;30:216 Pictet-Spengler reaction 1:139,140; 4:13,16,17,23 ;10:87;13:408-410; 14:633,759,761,763 (+)-endo-6-bromocamphor from 4:644 Pictet-Spengler type reaction 19:91 of tryptamines 19:91
Piericidin 28:435 as inhibitor of 28:435 Piericidin A 28:436 as complex I inhibitor 28:436, 437 Piericidin B! N-oxide 15:457 Piericidins 15:457,458 Pieris brassicae 26:702 Pieris rapae 18:771;26:439 Pierreodendrom kerstingii 7:369,379, 398 Piers annulation 6:21,22 of methylene cyclophexane 6:21,22 Piers synthesis 6:22 ofpalauolide 6:22 PIFA 21:391 Pig liver esterase (PLE) 13:56 asymmetric hydrolysis with 1:685 Pig pancreatic lipase 1:685,686 asymmetric hydrolysis 1:685, 686 Pigment-producing parasites 25:25 Pikramycin 11:161 Pikronolide 11:158-163 synthesis of 11:158-163 Piliformic acid 21:197 (c~ S, 13R)-Pilocarpine 16:697-698 synthesis of 16:697-698 Pilocarpine 21:488,753,754;22:19,736; 25:530 Pilocarpine-M-receptor complex 21:754 Pilocarpusjaborandi 27:522 Pilocarpus sp. 21:488 Pilosine 25:530 Pimagnolin 30:592 as EBV inhibitor 30:592 Pimarane 25:241 Ent-Pimarane 9:267,283-288 Pimarane diterpenes 23:842 Pimarane skeleton 19:395 Pimarane-type diterpenoids 20:688-690; 21:721 Pimaricin 6:261 relative configuration of 6:261 Pimenta dioica 28:398,403 acaricidal activity of 28:403 Pimenta racemosa 29:99
634
Pimpinella anisum 28:427 acaricidal activity of 28:427 Pimpinella anisum 5:473;28:427 Pimpinella sp. 28:431 ( 1E)-propenyl-4-hydroxybenzene from 28:431 against Typhlodromus telarius 28:431 epoxy-anoltiglate from 28:431 epoxy-seudoisoeugenolisobutyrate from 28:431 epoxy-pseudoisoeugenoltiglate from 28:431 isoeugenolisobutyrate from 28:431 phenylpropanoids from 28:431 pseudoisoeugenolisobutyrate from 28:431 Pimpinellin 22:522,539 Pimprinine 22:533,641 Pinaceae 25:245,246,249 Pinacol 8:18 titanium induced coupling 8:18 Pinacol (1-bromoallyl) boronate 11:424 (c~-alkoxyallyl) boronic ester from 11:424 Pinacol coupling 18:443 Pinacol rearrangement 11:52-54; 14:360-362;15:500;18:174;19:397; 24:785,786 of arboreol 24:785,786 of hydronaphthalene- 1,10-diol monosulfonate esters 14:356 of 9f3-hydroxy- 11-oxoderivative 19:399 Pinacol-pinacolone rearrangement 16:127 of diol 16:127 Pinacol-type derivatives 8:4 (-)-cis-Pinane 17:605 (R)-Pinane diol 11:410 Pinane monoterpenoids 25:153 (S)-Pinanediol 11:410 from (+)-ot-pinene 11:410 synthesis of 11:410 (S)-Pinanediol (dichloromethyl) boronate 11:411
(S)-Pinanediol [(1R)- 1-chloroalkyl] boronate 11:411 (R)-Pinanediol [(IR)- 1-chloroethyl] boronate 11:414 (S)-Pinanediol [(IS)-l-chloroalkyl] boronates 11:410,411 synthesis of 11:411 (S)-Pinanediol [(benzyloxy) methyl] boronate 11:420,421 L-ribose from 11:420,4421 serine from 11:420 (S)-Pinanediol boronic esters 11:410, 411 Pinanediol esters 11:412-414 insect pheromones from 11:412-414 (R)-Pinanediol methyl boronate 11:414 eldanolide from 11:414 (S)-Pinanediol phenylboronate 11:417, 418 (2S,3S)-phenylalanine-3-d from 11:417,418 (S)-Pinanediol propylboronate 11:412, 413 (3S,4S)-4-methyl-3-heptanol from 11:412,413 Pine 20:16 Pine tall oil 14:642 Pinellia ternata 24:272 (+)-[3-Pinene 27:372 (-)-[3-Pinene 16:234,235,239,245,248; 27:372 Ritter reaction of 11:281,282 with 3-indolyl acetonitrile 11:281,282 (+)-cc-Pinene 4:644;8:477;13:72; 16:147,234,242;20:594 ;27:373 (-)-ot-Pinene 27:385 structure of 8:477;11:280;27:385 a-Pinene 7:95,99-101,105-107;8:474, 475,478;21:582,598,601,619,622; 22:663;25:125,145,149,151 as chiral auxiliary 8:475 hydroboration of 8:475 [3-Pinene 9:350;13:336;20:594;21:582, 607,619,622;25:145,154 a-Pinene epoxide 25:153 Pinguisenol 2:283,287
635
(-)-Pinidine 14:572 from Pinus sp. 14:572 synthesis of 16:482 Pinifolic acid 25:258 (+)-Pinitol 18:431 Pinitol 7:181 Pinna muricata 19:616;25:871;28:657 Pinnaic acid 19:616 Pinnatazane 5:216,9:81 Pinnatifidone 5:216,217;9:81-83,87 (+)-Pinnatol-D 6:26 from Laurencia pinnata 6:26 synthesis of 6:26 Pinnatoxin 19:616 Pinner reaction 5:557,558,561,566,574 Pinns strobus 25:245 Pinobanksin 30:729 structure of 30:729 Pinocarveol 25:153 Pinocarvon 20:13 Pinocembrin 7:228;9:399,400;23:802, 821 ;28:229;30:728 biological activity of 28:229 structure of 30:728 (+)-Pinoresinol 5:523,526,526,538; 20:619;26:157,177,188,200,229,270, 474 Pinoresinol 5:464,465,557,558,561, 566,574 ;26:249;27:760 polymerization of 27:760 epi-Pinoresinol 5:489-492 (+)-epi-Pinoresinol 5:522,526,530 O-glucosylation of 5:525 O-methylation of 5:525 (+)-Pinoresinol diglucoside from 26:235 Pinoresinol dimethyl ether 26:233 neojusticin B 26:235 (+)-Pinoresinol dimethyl ether 26:241 as PAF-induced inhibitor 26:241 (+)-epi-Pinoresinol dimethyl ether 5:526 (+)-Pinoresinol dimethyl ether 5:526, 536 (+)-l-Pinoresinol dimethylether 26:200 (-)-Pinoresinol di-13-D-giucoside 26:200 Pinoresinol monoglucoside 26:235
(+)-Pinoresinol monomethyl ether 5:526;26:200 (+)-Pinoresinol monomethyl ether [3-Dglucoside 5:526 (+)-Pinoresinol-4'- [3-D-glucoside 5:523 (+)-epi-Pinoresinol-4'-~-D-glucoside 5:526 (+ )-Pinoresinol-di-O-[3-D-glucos ide 20:646 (+)-Pinoresinol-di- [3-D-glucoside 5:523 (-)-Pinoresinol-[3-D-glucoside 26:200 (+)-Pinoresinol-[3-D-glucoside 26:200, 270 (+)-Pinostrobin 23:821 Pinostrobin 7:228 Pinosylvin 22:627 Pinosylvin monomethyl ether 26:472 (i)-Pinresinol 26:267,268,269 Pinus 26:905 Pinus canarienis 26:859 Pinus caribaca 25:151 Pinus densiflora 26:471 Pinus flexilis 26:887;27:853 Pinus halepensis 28:420 Pinus koraensis 5:701,702 Pinus maritima 29:583 Pinus massoniana 26:472,474 Pinus nigra 25:249;28:420 Pinus palustris 25:151 Pinus parviflora 30:407 acidic polysaccharide from 30:407 Pinus peuce 27:370, 372 Pinus pinaster 28:420 Pinus pinea 28:420 Pinus radiata 7:99,101,105,106,108, 109 Pinus sp. 7:106;21:501;27:372 Pinus sylvestris 17:604,19:247; 23:342;25:249,666;27:370 Pinus thunbergii 19:247,18:498;21:417; 26:471 Pinusolide 25:275;29:102 activity in CRO bioassay system 29:102 Piocarvone 25:153 Piophocarpus tetragonolobus 19:247 Pi-Pd complex 10:59
636
Pipecolic acid 13:475 Piper acutisleginum 24:693,695 Piper aduncum 24:699,711,712 Piper amalago 24:685,687,688, 691-694,699-702,704,710,712 Piper amides 24:683-783 biological activity 24:708-715 isolation of 24:705-708 structure elucidation 24:705-70 synthesis of 24:717-733 Piper argyophyllum 24:686,695 Piper attenuatum 24:693,695,697 Piper aurantiacum 24:699,709,710 Piper betel 24:693,695,710;26:243,469 Piper brachystachyum 24:688,692,697 Piper callosum 21:378;24:692,693,704, 710,711 Piper chaba 24:692,709,710,711 Piper clusii 20:619 Piper decurrens 26:232 Piper demeraranum 24:700 Piper futokadsura 24:695;26:240 kadsurenin from 26:240 kadsurenin H from 26:240 Piper guineense 17:317;21:378;24:684, 686,692-698,703-705,709,711,712, 716,717 Piper kadsura 26:240 denudatin 26:240 Piper khaslana 24:693 Piper longum 21:379;22:509,529; 24:686,691,692,695-697,699,702, 709,710 Piper mantii 24:697 Piper marginatum Jacq. 27:16 trans-anethole from 27:16 Piper maritmus 24:687-689,695,705, 709,710,712 Piper methysticum 13:660;22:508,530; 24:711,799 kawain from 13:660 Piper nigrum 10:152;21:379;22:530; 24:273,683,686,687,689,691-697, 701,704;26:819 piperine from 26:819 Piper novae-hollandiae 24:686,692, 693,695,711,712 Piper officinarum 10:151;24:689,695, 697,709,710
Piper ovatum 21:378;24:684,704,710 Piper peepuloides 24:707,709 Piper puberulum 26:243 puberulin A&C from 26:243 Piper regnellii 22:358 Piper retrofractum 22:530 Piper ridley 24:697,698,705,707 Piper sarmentosum 21:378;24:686, 687,697,702,709-712,731 ;29:684 Piper schmitii 24:700 Piper sp. 24:683-738 Piper sumatranum 17:348 Piper sylvaticum 21:378;24:686,695, 709,712 Piper trichostachyon 21:378;24:687, 694,696,697 trichostachine from 21:379 trichonine from 21:379 Piper umbelata 22:358 Piper wightii 24:700 Piperaceae 21:373,374 Piperadinoisoquinolines 12:447 2,5-Piperazine dione 10:84,90,125 Piperazinedione 12:81,82;28:359 from d,/-homoserine 12:81,82 sulfenylated 12:81,82 Piperazines 10:638,640 from diketopiperazines 10:638 Piperazinomycin 10:630,631,652 synthesis of 10:638-640 X-ray crystal structure of 10:638 Piperbetol 26:243,244 as PAF-induced inhibitor 26:243 pipercallosine from 21:379 piperovatine from 21:379 Pipercide 21:379,381,383 Piperettylpyrrolidine 21:379,3821Piperic acid 21:374,378 Pipericide 10:152 Az-Piperideine 14:739 1,4-addition of 14:754,755 AI-Piperideine 14:739,753,759 A3-Piperideine 14:753,754 Piperideine 6:424,429 from cyclopentanone 6:424,429 cis reduction of 6:428 trans reduction of 6:428 synthesis of 6:422-434
637
Piperidine 9:70-73;10:671,672;14:739; 21:378;22:739 glycosidase inhibitors of 10:524 (2S)-Piperidine 23:190 Piperidine alkaloids 6:422-434; 13:474-483 ;21:106;25:528 fl-alanine-3-aminopropionic acid 25:537 anabasine 25:521 7-coniine 25:528 from Nitraria species 14:742-765 guvacine 25:537 isoguvacine 25:528 (-)-lobeline 25:528 (+)-N-methylconiine 25:528 nicotine 25:528 nipecotic acid (3-piperidinecarboxylic acid) 25:537 nomicotine 25:528 synthesis of 16:453-502 Piperidine alkaloid hydrochloride 30:204 antinociceptive action of 30:204 Piperidine derivatives 14:557,578 1H-NMR spectra of 14:557,578 (R)-(+)- ct-methoxy- a(trifluoromethyl) phenyl acetyl ester from 14:557,578 (-)-ajmalicine from 14:563,564 (-)-tetrahydroalstonine from 14:563,564 (+)-yohimbine from 14:566,567 absolute configuration of 14:557,558 diastereoselective synthesis of 12:471-476 from (R)-l-phenyl ethyl amine 14:555,556 from (S)-1-phenyl ethyl amine 14:555,556 optical purity of 14:557,558 Swern oxidation of 14:572 synthesis of 12:471-476; 14:553-559 Piperidine venom alkaloids 6:423 distribution of 6:423 in ants 6:422-434
Piperidinium salt 14:753,754 A3-piperdeine from 14:753,754 reduction of 14:753,754 4-(4-Piperidly) indoloquinolizidine 14:761 from nitrarine 14:761 via schoberidine 14:761 3-Piperidinol alkaloids synthesis 29:419 by stereodivergent process 29:419 Piperidiol 21:147 1-(2-Piperidyl)-propan-2-ol 12:284 Piperine 22:530,541 (+)-cis-Piperitol 5:701,702 Piperitenone 25:150;29:83 activity in AM assay system 29:83 (+)-Piperitone 16:264;29:83 activity in AM assay system 29:83 (-)-Piperitone 6:15 (-)-zonarene from 6:15 Piperitone 9:530 Piperlongumine 24:703 Piperlonguminine 21:378,382 Piperol A 26:243,244 as PAF-induced inhibitor 26:243 Piperol B 26:243 as PAF-induced inhibitor 26:243 Piperonal 4:13,14 Piperonyl butoxide 5:402 Piperylene 24:708 Pipitzol 1:568;5:792-794 synthesis of 1:568 transformation from perezone 5:792-794 [3-Pipitzol 5:781 CD curves of 5:781 chemistry of 5:782-785 isolation/structure of 5:778-782 stereochemistry of 5:781 synthesis of 5:782,799,800 ~-Pipitzol 5:782,799 CD curves of 5:782,799 chemistry of 5:782-785 13C-NMR spectrum 5:786-785 isolation/structure of 5:778-782 stereochemistry of 5:781
638 13-Pipitzol derivatives 5:783-785 chemistry of 5:783-785 Pippali 21:379 Piptocalyx moorie Oliv. 4:709 [3-Piptzone 5:783 from O-methyl-b-pipitzol 5:783 Piqueria trinervia 24:779,817-819; 28:404 diterpenes of 24:817 herbicidal activity of 24:819 monoterpenes of 24:817 toxicity to gravid female ticks 28:404 Piquerol 26:807 Piquerol A 24:819,820;28:404,405 acaricidal activity of 28:404 diacetate 24:820 in control of vector 24:819 Piquerol B 28:404 acaricidal activity of 28:404 toxicity to gravid female ticks 28:404 Pirano flavonoids 26:744 Piricularia oryzae 2:434;23:112; 26:1210 Pirkle reagent 9:241 Pironetin 30:3,26-46 ( 5R, 6R)-5-ethyl-5,6- dihydro6[(E)-(2R,3S,4R,5S)-2-hydroxy4-methoxy-3,5-dimethyl-7nonenyl]-2H-pyran-2-one 30:29 13C NMR of 30:29 ~H NMR of 30:29 against transplanted murine tumor cell lines P 388 leukemia 30:27 antitumor activity of 30:27,28 as antitumor agent 30:3 as immunosuppressive agent 30:3 as plant growth regulator 30:26 biological activity of 30:26 effect on 3Y1 cell 30:27 biosynthesis of 30:26,29 Chida's synthesis of 30:38-40 Dias synthesis of 30:44-46 effect on cell cycle progression 30:27
effect on DNA content 30:27 Gurjar's syntheses of 30:33-37 immunosuppressive effect of 30:26 IR of 30:29 isolation of 30:26 Kawada's synthesis of 30:30-33 Keck's synthesis of 30:42-44 Kitahara's synthesis of 30:40-42 structure elucidation of 30:26 structure of 30:3,27 synthetic routes to 30:3,30 X-ray crystallographic analyses of 30:29 Pironetin derivatives 30:27 effect on uterine tumor 30:27 effect on ovarian tumor 30:27 Piroxicam 20:514 Pisaster brevispinus 15:61 pisasteroside A from 15:61 Pisaster giganteus 15:66 Pisaster ochraceus 15:61 pisasteroside A from 15:61 Pisasteroside A 15:61 from Pisaster brevispinus 15:61 from Pisaster ochraceus 15:61 Pisatin 12:399 by K-252a 12:399 inhibition of 12:399 in pea epicotyls 12:399 Piscerythrol 22:473 Piscicidal activity 2:289 of frullanolide 2:289 of liverwort terpenes 2:289 ofplagiochiline A 2:289 ofpolygodial 2:289 of sacculatal 2:289 Pisidium guajava 5:837 hemoglobin components of 5:837 Pisiferal 20:673 from Salvia acetobulosa 20:673 from Salvia multicaulis 20:673 Pisiferic acid 29:170 analogues of 29:170 antibacterial activity of 29:170 antifungal activity of 29:170 as abietane type diterpene acid 29:170
639
dehydroabietic acid analogue of 29:170 effects on DNA synthesis 29:170 ferruginol analogue of 29:170 podocarpic acid analogue of 29:170 Pisiferic acid synthesis 29:173 by Banerjee 29:174 by Geiwiz and Hasslinger 29:185 by Mori and Mori 29:182 by Pal and Mukerjee 29:180 enone cyclization in 29:173 from abietic acid 29:188 ketones preparation in 29:174 starting materials for 29:177 transannular oxidation in 29:173, 174 yield in 29:174 Pissodes 27:384 Pistachia vera 9:316,327,339 Pistacia chinensis 28:234 Pistacia integerrima 21:582;22:118 Pistacia lentiscus 29:580 Pistacigesrimone A 22:118 Pisum sativum 17:402;18:708,710; 19:247;25:93,417;26:832,1263; 29:599,605 Pitasalbine 4:615 synthesis of 4:615 Pithecellobium dulce 21:657 Pithecolobium saman 22:530 Pithomyces sp. 9:203 ;25:172 (2R,5S)-Pitoyl 25:144 Pituranthus tortuosus 27:687 Pityol 1:692 formation from sulcatol 1:692 synthesis of 1:691,692 Pityrophthorus pityographus 1:692; 25:144 Pityrosporium sp. 13:309 Piulella xylostella 23:66 Pivalate ester 1:312,313 Pivaloyl chloride 12:322 in aldolate trapping 4:17,18 Pivaloyl group 6:292,293 protection with 6:264,268,276, 282,283 Pivaloylation 13:32
PK-1051 21:408 PKA 25:541 inhibitor of 25:541 PICA inhibitors 25:527,538,542,550 acridine based 25:542 ellagic acid as 25:550 isoquinoline based 25:542 phenanthrene based 25:542 PKA-catalyzed phosphorylation 25:529 PKA-gated Na + channels 25:521 PKC 25:271,526,536,543,721,726 diacylglycerol activated 25:66 PKC activation 30:71 inhibition of 30:71 PKC inhibitor 25:544,550 ellagic acid as 25:550 PKG 25:523,527 PLA2 25:669,695,696,704,902 Placenta 30:561 role of Hernandia moerenhoutiana in 30:561 role of Hernandia nymphaeifolia in 30:561 role of Hernandia voyronii in 30:561 Placentoside A 7:302 from Sphaerdiscus placenta 7:298 Plactranthus caninus 7:119 Plagiochila 21:281 Plagiochila acanthophylla 2:81,280 Plagiochila hattoriana 2:280 Plagiochila yokogurensis 2:280 Plagiochiline A 2:279,280,288 Plagiochiline B 2:279,280 Plagiochiline C 2:287 Plagiochiline I 2:279,280 Plagiochins 20:291 Plagiolactone 16:216 Plain peptide signals 25:402 Plakellia sp. 25:715 Plakinastrella sp. 26:73 Plakorin 23:211 Plakortin 5:354,355;9:18 Plakortis 23:201;26:492 Plakortis angulospiculatus 18:719 Plakortis halichondroides 18:719 Plakortis lita 5:353,354;18:718,719; 23:201;25:724
640 Plakoside A and B 25:721 Plakosides 25:722 Plamepsin I and II 25:330 Plamitoleic acid 30:65 from carp oil 30:65 Planaxis sulcatus 17:22,28 Planaxool 17:22,23 Plane of polarization 2:159 rotation of 2:159 Planinin 26:267 Plankoilide 25:724 Plankortis simplex 25:721 Planotortaix excessan 7:193 Planotortaix leafroller 7:193 Plant extracts 24:524-526 in vitro antiviral activity 24:524-526 Plant growth regulator 26:934-935 role of nitric oxide in 26:934-935 Plant growth regulatory activity 2:289 of liverwort terpenes 2:289 of polygodial 2:289 Plant growth stimulants 9:383,384 Plant injury 27:59-88 chemical responses to 27:59-88 Plant Kunitz serine protease inhibitor proteins 29:603 ACTI-A (ACTI-A-S-S- ACTI-B) as 29:603 A-II & A-III (22 kDa), B-I & B-II as 29:603 BASI (barley a-amylase & subtilisin inhibitor) as 29:604 BnD22 as 29:603 BoKPI as 29:603 Carica KPI as 29:604 CLSI-II as 29:603,604 CoATi as 29:606 DE5 as 29:603 DrTI as 29:604 ECI as 29:604 effects on actinidin ananain 29:606 effects on chymotrypsin 29:603,604 effects on chymotrypsin kallikrein plasmin 29:604 effects on elastase 29:603,606
effects on ETI-a - plasminogen activator 29:604 effects on Factor XIIa 29:603 effects on inferred KPI (wounding-induced Kunitz homologue) 29:605 effects on Kallikrein 29:603,604 effects on KPI homologues 29:604 effects on Kunitz PI homologue 29:605 effects on serine protease 29:603 effects on soybean KPI homologue 29:605 effects on STI (Kunitz) homologue 29:604 effects on subtilisin 29:604,605 effects on subtilisin BPN' proteinase K 29:603 effects on trypsin 29:603,604 Enterolobium EcTI as 29:604 Erythrina DE-1, DE-2, DE-3, DE-4 as 29:604 Erythrina ETI-a ETI-b as 29:604 from Acacia confusa 29:603 from Adenanthera pavonina 29:603 from Albizziajulibrissin 29:603 from Alocasia macrorrhiza 29:603 from Arabidopsis thaliana 29:603 from Bauhinia bauhinioides 29:603 fromBauhinia mollis 29:603 from Bauhinia pentandra 29:603 from Bauhinia variegata (mountain ebony) 29:603 from Brassica napus 29:603 from Brassica oleraceae 29:603 from Canavalia lineata 29:603,604 from Carica papaya 29:604 from Delonix regia 29:604 from Enterolobium contorsiliquum 29:604 from Erythrina caffra 29:604 from Erythrina latissima 29:604 from Erythrina variegata 29:604
641
from Glycine max 29:604 from Hordeum vulgare 29:604 from Ipomoea batatas 29:604 from Lycopersicon esculentum 29:604 from Nicotiana glauca 29:604 from Nicotiana glutinosa 29:605 from Nicotiana langsdorffii 29:604 from Oryza sativa (rice) 29:605 from Pisum sativum (pea) 29:605 from Populus deltoides 29:605 from Populus balsamifera 29:605 from Populus tremuloides 29:605 from Populus trichocarpa 29:605 from Prosopisjuliflora 29:605 from Psophocarpus tetragonolobus 29:605 from Richadella dulcifica 29:605 from Salix viminalis 29:605 from Schizolobium parahybum 29:605 from Solanum tuberosum 29:605 from Swartzia pickellii 29:606 from Theobroma cacao 29:606 from Triticum aestivum 29:606 ct-fucosidase as 29:605 pF4 & pKEN 14-28 KPI genes as 29:606 T-CDI-B1 KPI genes as 29:606 genes encoding KPI-like proteins as 29:603 GTPI as 29:603 gwin3 as 29:605 heat-stress-induced protein (HTI) as 29:603 KPI as 29:603 KTi-S as 29:604 Kunitz PI homologue AM66 as 29:606 Lycopersicon Miraculin-like protein as 29:604 Lycospersicon TI gene as 29:604 miraculin (MIR) as 29:605 NgPI as 29:605
p20 as 29:604 p340 & p34021 as 29:606 PCPLs homologues as 29:606 PI-4, PIG, CDI homologue as 29:605 PjKTI as 29:605 PKI-1 as 29:606 potato cysteine protease inhibitor as 29:605 potato serine protease inhibitors PSPI-21-5.2 as 29:606 Pt nodulin as 29:605 pTI as 29:606 PtTI1, PtTI2 & PtTI3 as 29:605 rice a-amylase-subtilisin inhibitor as 29:605 SPC as 29:605 sporamin A & sporamin I3 as 29:604 SVTI as 29:605 SWIN1.1 as 29:605 SWTI as 29:606 TPP 11 (gene expressed in flower tissue) as 29:604 tumour-related protein as 29:604 WASI as 29:606 water-soluble chlorophyllcarrying protein as 29:603 WBA-1 as 29:605 WBTI-2 as 29:605 WTI-1 as 29:605 Plant peptides 29:594 Ala-Phe dipeptide as 29:594 Ala-Pro-Gly-Ala-Gly-Val-Tyr septapeptide as 29:595 Asp-Ile-Gly-Tyr-Tyr pentapeptide as 29:595 Asp-Tyr-Val-Gly-Asn entapeptide as 29:595 derived from plant protein proteolysis 29:594 effects on ACE enzyme 29:594596 glutathione (tripeptide) as 29:595 Gly-Gly-Val-Ile-Pro-Asn (hexapeptide) as 29:595 His-His-Leu (tripeptide) as 29:595
642
Ile-Arg-Ala (tripeptide) as 29:595 Ile-Arg-Ala-Gln-Gln (pentapeptide) as 29:595 T-L-glutamyl-(+)-allyl-L-cysteine sulphoxide (dipeptide) as 29:595 Thr-Val-Val-Pro-Gly (pentapeptide) as 29:596 Val-Ser-Pro (tripeptide) as 29:596 Val-Tyr (tripeptide) as 29:596 Plant peroxidases 27:737 as versatile catalysts 27:737 Plant polyphenols 28:257,281,300 anthocyanins as 28:257 bioactivity of 28:257 epidemiological studies on 28:300 flavanols as 28:257 flavanones as 28:257 flavones as 28:257 in humans 28:281 isoflavones as 28:257 occurrence of 28:257 proanthocyanidins as 28:257 structure of 28:257 Plant polysaccharides 19:692 Plant proteases 25:389 Plant pyrolysins 25:392 Plant regulatory activity 28:480 ofpodolactone E 28:480 Plant serpins 29:613 BSZ4 as 29:613 BSZ7 as 29:613 BSZx as 29:613 effects on 4APC, cathepsin G 29:613 effects on cathepsin G 29:613 effects on chymotrypsin 29:613 effects on elastase 29:613 effects on elastase, factors VIIa/TF, Xa, XIIa, kallikrein 29:613 effects on serine protease 29:613 effects on thrombin 29:613 effects on trypsin 29:613 Rye serpins RSZa, RSZb, RSZc 1, RSZc2, RSZd, RSZe & RSZf as
29:613 WSZ1 as 29:613 WSZlb as 29:613 Plant sources 23:547 of omuseka 23:657 of onagraceae 23:404 of oosponol 23:355 of opportunistic infection (OI) 23:4 of orchinol 23:342 Plant tissue culture 7:120-126 applications of 7:120-126 degradation processes in 7:103-107 techniques of 7:89-96 terpenoids synthesis by 7:87-129 Plantago major 29:84 Plantainoside D 25:543 Plants 24:490-544;25:459 alkaloids from 24:493-497 antiviral compounds from 24:492-544 as antiviral agents 24:490-544 carbohydrates of 24:497,498 hepatoprotective effect of 25:106 Plaque forming units (PFU) 24:483 Plasma desorption (PD) MS 2:50;9:487 Plasma glucose 27:412 biological activity of 27:412 Plasma ions 2:3 Plasma LDL 23:739 Plasma membrane H§ 25:374 Plasma membrane-located receptors 25:518,522 Plasma-cholestrol lowering activity 23:512 of saikosaponins 23:512 Plasma-membrane-located signals receptors 25:518 Plasmepsin 25:352 Plasmepsin I 25:331 Plasmepsin II 25:331 Plasmid 9:592,593 Plasmin 30:830,838 Plasmin-activator 30:839 EFE as 30:839 Plasminogen activator (e-PA) 30:826 from Eiseniafetida 30:827 Plasminogen activator (t-PA) 25:221
643
Plasminogen activator inhibitor (PAI) 30:844 Plasminogen activator inhibitor- 1 (PAI- 1) 27:433,435 Plasminogen inhibitors 30:841 from Eiseniafetida 30:841 role in tissue protection 30:841 Plasmodia 25:348 Plasmodium 25:327,544;26:779-781, 797,798,800,802-804,815,825,1030, 1035,1036,1063 Plasmodium berghei 7:391,394,395; 25:333,338,341 ;26:1063 Plasmodium chabaudi 26:789 Plasmodium falciparum 7:391,392394,424;13:656;20:516,517,519522;21:744;22:145;23:238,819; 25:328,330-332,334,336,338, 340-342,345,348,350-352,359,527, 814 ;26:230,231,456,466,781-783, 788,789,797,800,801,804,805,808, 811,813,815,816,819,820,822-824, 828,837-839,1037,1063 ;28:148; 29:569 antimalarial activity of 7:424 Plasmodium genus 19:587 Plasmodium lophurae 26:803 Plasmodium malariae 20:516,517; 25:328;26:781,837 Plasmodium ovale 20:516;26:781,789 Plasmodium strains 30:694 against human adenocarcinoma cell line HT-29 30:694 Plasmodium vivax 20:516;25:328; 26:781,783,789,803,837 Plasmodium yoelii 21:744;26:789,828 Plasmopara viticola 27:768 Plastoquinone 26:368 Platelet 30:593 role in hemostatic process 30:593 Platelet activating factor (PAF) 26:240-245 ;30:594 and antagonism 26:240-245 and coagulation 26:240-245 as potent phospholipid inflammatory mediator 28:188 by inhibiting phospholipase A 2 12:397
platelet aggregation induced by 30:594 Platelet activating factor antagonist activity 26:183 effect of Schisandra on 26:183 Platelet activation 30:70 role of serine protease in 30:70 role of thrombin in 30:70 Platelet aggregation 12:397;21:263; 26:756,758;30:593,594,838 arterial thrombosis due to 30:593 collagen induction by platelet activating factor (PAF) 30:594 induction by arachidonic acid 30:594 induction by thrombin 30:594 inhibition of 12:397 Platelet aggregation inhibition 23:357 of osthole 23:357 and ovarian cancer 23:294 Platelet aggregation inhibitor 1:4; 28:16,17;30:594 broussoaurone A as 28:16,17 broussoflavan A as 28:16 broussoflavonol E as 28:17 broussoflavonol F as 28:17 (-)-deoxypodophyllotoxin as 30:595 (-)-hernone as 30:595 (-)-yatein as 30:595 (+)-epiaschantin as 30:595 (+)-epimagnolin as 30:595 (+)-epiyangambin as 30:595 (+)-hernandaline as 30:594 (+)-laurotetanine as 30:594 (+)-malekulatine as 30:594 (+)-ovigerine as 30:594 (+)-reticuline as 30:595 (+)-thalicarpine as 30:595 (+)-vateamine-2 ' [~-N-oxide as 30:595 7-oxohernagine as 30:595 dehydrohernandaline as 30:594 Hernandia species as 30:594 hernangerine as 30:594 isoquinoline alkaloids as 30:594 isovanillin as 30:594 lignans as 30:594 N-methylhernangerine as 30:594
644
Platelet antiaggregant 25:595 Platelet arachidonate metabolism 27:422 of polyacetylene compounds 27:422 Platelet serotonin (5-HT) 30:380 in autistic patients 30:380 Platelet-derived growth factor (PDGF) 15:441 ;25:593,598 Platenonolide 11:163 Platycarya 26:905 Platycarya genera 27:755 Platycarya strobilacea 26:899 Platycaryol 26:899 Platycodi radix 30:89,91 effects on liver triacylglycerol 30:89 effects on liver weight 30:89 effects on plasma triacylglycerol level 30:90 effects on total cholesterol 30:89 Platycodon grandiflorum 22:97 Platyconin 5:640 Platynecine 1:237,238;3:54;13:484,485 synthesis of 1:246 Platyphyllone 17:361 Platystemon genera 27:163 Plausibe mechanism 19:392 Plaustroside I 25:104 (PLE) (Pig liver esterase) 13:56 Pleckstrin homology 25:525 Plectranthus 25:238 Plectrinone A 23:530 Pleiocarpa mutica 1:124 Pleiocarpa talbotii 13:397,424 Pleiocarpamine 5:125,126;9:179; 13:397,405 16-epi-Pleiocarparrflne 5:126,128 Pleiocarpamine-type alkaloids 5:82,83 pleiocarpamine 5:82,83 16-epi-pleiocarpamine 5:83 Pleiotropic effect of TNF-a 25:460 Pleisopermium alarum 13:351,20:497 Pleraplysilla spinifera 6:72 spiniferin 1 from 6:72 Pleuran 23:115 Pleurobranchus forskalii 25:887;28:642 Pleuromutilin 3:88,89
(+)-Pleuromutilin 8:418 by double Michael additon 8:418 synthesis of 8:418 Pleuronectes platessa 25:131 Pleurotellol 3:7,65 Pleurotus glabellatus 25:131 Pleurotus ostreatus 5:288;23:115,119; 26:111 Pleurozia acinosa 25:252 Plexaura homomalla 9:570 Plexiglass 22:375 Plicacetin 4:244 activity of 4:244 synthesis of 4:244 Plinthogali 17:200 Plocamadiene A 25:701 Plocamium 25:701 Plocamium cartilagineum 18:714; 25:701 Plocamium castatum 25:701,781 Plocamium coccineum 17:9 Plucchea sagittalis 22:349 5,3',4'-trihydroxy-3,6,7-trihydroxy-3,6,4 '-trimethoxyflavone from 22:349 5,7,3' -trihydro xy- 3,6,4 ' -trime thoxy-flavone from 22:349 5,7,3 ',4'-tetrahydoxy-3,6,8trimethoxy flavone from 22:349 Pluchea arguta 5:202,204;9:65;24:112 Pluchea lanceolata 22:117 Pluchea sp. 9:65-68 sesquiterpenes from 9:65-68 Pluchecin 5:203,204;9:66 Pluchecinin 5:205;9:66 4-epi-Pluchecinol 9:66 Pluchidinol 9:66-69 Pluchidione 9:66,67,69 Plumaran-type akaloids 5:71,89, 165-174 Plumbagic acid 2:228 biosynthesis of 2:228 Plumbagin 2:212,214,215,222;4:612, 613;26:470,804 Plumbago scandens 2:225 Plumbago zeylanica 2:215,226;22:530 quinones of 2:212-231
645
Plumbaseylanone 2:229,230 biosynthesis of 2:229,230 conversion to methylene-3,3'biplumbagin 2:218,219 conversion to plumbagin 2:218, 219 mass spectral fragmentation of 2:221 structure of 2:218-221 Plumeran 26:140 Plumericin 7:441 synthesis of 16:29%301 Plumieride 7:439 Pluradomycins 4:432 in carbapenem 4:432 PLUTO plots 9:281 Pluviatilol 5:703 Pluviine 20:352 PMA 25:938 inhibitor of 25:938 PMA-thrombin 30:70 inhibition of 30:70 PM-located voltage-gated Ca 2+channels 25:534 PMT 21:157,176,177 preclinical development of 21:176 Pneumocandins 22:69;23:343 Pneumocystis carinii 2:421;22:248; 26:804,835 PNU-141962 28:353 isotopic labeling of 28:353 Poa annua L. 27:217 Pocine pancreatic elastase (PPE) 30:830,831,843 homologous sequences of 30:831 Podachaenin 29:90 activity in NFkB assay system 29:90 Podachaenium eminens 29:89 (+)-Podocardic acid 14:639-642 synthesis of 14:639-642 Podocarpaceae 25:246 Podocarpane 9:297;25:241 (+)-Podocarpic acid 10:407 Podocarpic acid 14:667-670 taxodione from 14:667-670
D-Podocarpic acid 4:405-408 in (+)-confertifolin synthesis 4:405-408 in (+)-isodrimenin synthesis 4:405 synthesis of 4:405-407 Podocarpus dacrydioides 14:449,450 (-)-selin- 11-en-4ct-ol from 14:449,450 Podocarpus elatus 29:10 Podocarpus ferrugineus 25:246 Podocarpus gracilor 28:462 Podocarpus hallii 28:462 Podocarpus macrophylus 28:462 Podocarpus milanjianus 28:464 Podocarpus nagi 21:602;28:464;29:579 Podocarpus nakaii 28:463;29:10 Podocarpus neriifolius 28:463 Podocarpus nivalis 28:458 Podocarpus nubigena 28:463 Podocarpus philippinensis 28:462 Podocarpus polystachyus 28:462 Podocarpus purdeanus 28:458 Podocarpus saligna 28:466 Podocarpus sellowii 28:464 Podocarpus sp. 28:453 Podocarpus totara 21:602;28:454 podolactones from 28:454 totarol from 21:602 Podocarpus urbanii 28:459 Podochaenium eminens 7:416 Podolactones 28:453,454,455,495 antifeedant activity of 28:454 anti-inflammatory activity of 28:453,454 anti-tumor activity of 28:453,454 biogenetic pathway for 28:455 fungicidal activity of 28:453,454 growth regulatory activity of 28:454,453 insecticidal activity of 28:453, 454 synthesis of 28:495 (-)-Podophyllotoxin 24:767 from endo addition 24:767 synthesis of 24:767 Podophyllotoxin 5:461,462,475,477, 478-483,485,488,489,493,494;11:5; 18:554,555,561 ;24:740;22:471,740;
646 26:149,154-159,166,168-178,184, 193,205,210,220,231,272,799,858 4-aminoaryl 26:162 derivatives of 24:740;26:162, 163,164 1-o-quinone 26:162 synthesis of 3:435;18:597-601; 24:740 Podophyllotoxone 5:480,481,483; 18:599
Podophyllum 26:149,151,153,154,156158,169-174,177,178,183,188, 205,210 antitumor activity of 26:210 Podophyllum bankakri 26:149 Podophyllum emodi 17:341;26:149,153, 154,156,158,171,173,178 podorhizol from 18:556 Podophyllum extracts 26:169 of antiviral activity 26:169 Podophyllum hexandrum 5:474,477, 480,482,483,485-497,488,493, 494;26:227 4 '- O- demethl dehdrop odophyllotoxin from 26:227 picropodophyllone from 26:227 Podophyllum peltatum 5:480,483-485, 493 ;17:341 ;18:557 ;24:269,774; 26:149-152,158,171-178;29:578 podorhizol from 18:556,557 podophyllotoxin derivatives of 7:416 Podophyllum sp. 5:461,477,481,483, 485,489,493 Podopyllotoxin-13-D-glucoside 26:193, 210 Podorhizol 5:484;18:554,565;26:192; 30:569,592 as EBV inhibitor 30:592 from Podophyllum emodi 18:556 from Podophyllum peltatum 18:557 acid catalysed cyclization 5:485 epi-Podorhizol 5:486 (+)-Podorhizon 18:588 Poecillastra sp. 19:580;25:731 Pogonomyrmex barbatus 5:250 Pogonopus speciosus 9:401 Pogonopus tubulosus 9:401
Pogostemom cablin 25:171 Pogostemon purpurascens 5:681 Pogostemon sp. 8:423 (-)-patchoulol from 8:423 (-)-seychellen from 8:423 Pogostol 23:812 Pohnpei 28:661
13-isothiocyanatocubebane from 28:661
1-isothiocyanatoaromadendrane from 28:661 2-thiocyanatoneopupukeanane from 28:661 4-thiocyanatoneopupukeanane from 28:661 thiocyanates from 28:661 Poison gland alkaloids 6:422-465 Poitediol 6:36 by Claisen reaction 6:36 by intramolecular aldolcyclization 6:36 by oxy-Cope rearrangement 6:36 from bicyclo [6.3.0] undecanone 6:36 from Laurencia poitei 6:35 from norearonols 6:36 Gadwood synthesis of 6:35-37 relation to dactylol 6:35 synthesis of 6:35-37 Pokweed mitogen (PWM) 25:271 Polar get theory 7:30,50,51 Polarized light 2:154 circularly 2:154 elliptically 2:154 linearly 2:154 Polauamine 25:784 Policimoside 23:640 Polio vaccine 25:817 Polio virus 30:411,743 replication of 30:411,743 use of antivirals 30:411 Polio virus type 1 30:743 antiviral activity of 30:743 Polio virus type 3 30:326 aloe-emodin against 30:326 Poliomyelitis 30:394,411 transmission of 30:411 vaccination against 30:411
647 Poliovirus SV 24:524 activity of actinoplanic acids against 24:524 Pollen 24:922-924 contraction by 24:922-924 Polonovski reaction 1:105-110,112; 14:715-746,811,815,816,857,858, 869-872 modified 4:31 Polonovski-Potier-Husson reaction 1:49,79,80 Polpunonic acid 7:146,150 Poly unsaturated fatty acid (PUFA) 25:932,948 (Poly) peptide hormones 25:387 (Poly) peptide ligands 25:385 Poly-3-hydroxybutanoate (PHB) 1:690 Polyacetylene alcohols 27:686 structure of 27:686 Polyacetylene compounds 27:422,660, 686,870 from acetonic extract 27:686 from panaxynol 27:870,871 from roots 27:686 Polyacetylenes 24:521,522,541-544 as antiviral compound 24:521, 522,541-544 Polyacrylamide 7:92 Polyacrylamide gel electrophoresis 4:283 for oligonucleotide purification 4:283 Polyalthia excessa 28:416 Polyalthia longifolia 28:416 Polyalthia viriclis 22:400 Polyamine biosynthesis 1:408 Polyamine-modulatory site 22:25 Polyamines 25:66 Polyandrocarpa sp. 10:248 Polyandrocarpamide A 23:241 Polyandrocarpamide B 23:241 Polyandrocarpamide C 23:241 Polyandrocarpamide D 23:241 Polyaromatic alkaloids 17:23 Polyarthritis 26:398 Polyasparagine 25:334 Polyazulenes 14:314 Polybrominated biphenylethers 17:10; 21:283,284
Polybrominated methylthioindoles 25:863 Polycanthisine alkaloid 27:251 NMR studies of 27:251,252 Polycarbocyclic marine triterpenoids 6:3-105 total synthesis of 6:3-105 Polycarpa 25:836 Polycarpa aurata 23:260;25:706, 836;28:640 Polycarpa clavata 28:640 Polycarpamine A 23:277;25:836;28:640 as disulfide alkaloid 28:640 as sulfur-containing antifungal agent 28:640 polycarpine as 28:640 synthesis of 28:640 Polycarpamine B 23:277;25:835,836; 28:640 as disulfide alkaloid 28:640 as sulfur-containing antifungal agent 28:640 polycarpine as 28:640 synthesis of 28:640 Polycarpamine C 25:836;28:640 as sulfur-containing antifungal agent 28:640 synthesis of 28:640 Polycarpamine D 25:836;28:640 as sulfur-containing antifungal agent 28:640 Polycarpamine E 28:640 as sulfur-containing antifungal agent 28:640 Polycarpine 23:240;25:836 Polycarpol 9:399,400 Polycavernosa tsudai 19:570 Polycavernoside A 19:571,572 stereochemistry of 19:571 toxicity of 19:572 Polycavernosides 19:570 Polycephalin B 28:134 structure of 28:134 Polycephalin C 28:134 structure of 28:134 Polychlorinated biphenyl 27:304 Polychlorinated dibenzodioxins 25:757 Polychlorinated dibenzo-p-dioxin (PCDD) congeners 30:763
648
Polychlorinated phenyl ether 25:792 Polycis-carotenoids 7:330-335 Polycis-prenols 8:66 Polycitone-A 23:242,251 Polycitor adriaticus 28:642 Polycitor sp. 25:834 Polycitorella mariae 25:837;28:634 citorellamine from 28:634 Polycitrins 23:242,245 Polyclinum planum 28:643 polyclinal from 28:643 Polyclonal antibodies 15:368 Polyclonal antibodies against ARS2 25:435 Polycondensation 7:458 Polycycles 8:278 synthesis of 8:278 Polycyclic amine alkaloids 24:573-672 13C-NMR data of 24:618-620, 652-655 monocyclic alkaloids of 24:611-612 pentacyclic alkaloids 24:619-662 tetracyclic alkaloids of 24:612 Polycyciic amine alkaloids 24:573-672 synthesis of 24:613-617 Polycyclic arenes 11:113 functionalization of 11:113 Polycyclic aromatic compounds 7:8-10 polyfunctionalized 11:113 synthesis of 11:119-127 via aromatic 13,[3,8,8-tetraoxoalkanedioates 11:119-127 Polycyclic pyridoacridines 23:276 Polycyclic terphenyls 29:286 as sarcodonin 29:289 4,5-dihydroxy- 1,2-benzoquinone core of 29:287 4',4"-dihydroxyphlebiarubrone as 29:286 episarcodonins as 29:290 epoxyenedione as 29:286 phlebiarubrone as 29:286 sarcodonin ot,[3,y as 29:290 spiromentins E-J as 29:288 Polycyclic-p-terphenyls 29:279 cycloleucomelone as 29:279 thelephoric acid as 29:279 Polydimethylacrylamide resin 18:921
Polydiscamide A 25:865,866;26:1201 Polyenal macrolides 6:261 biological activity of 6:261 in tumor therapy 6:261 Polyenamides 21:388 from fungi 21:388 Polyene acetal 14:471 tetracyclization of 14:471 Polyene amide 21:373 natural product with 21:373 Polyene antibiotics 25:299 Polyene cyclization 8:188 acid catalyzed 8:188 biomimetic 14:740 initiators 1:656 steroids from 14:740 Polyene macrolides 22:58 Polyene synthesis 20:571 Polyenoyltetramic acids 21:374,410, 413;28:132 Polyester sesquiterpenes 18:743 Polyether antibiotic 10:340;11:194 methylmalonyl CoA with 11:195 synthesis of 10:340 Polyether toxin 17:20 Polyethers 5:377-398 Polyethylene 22:375 Polyfibrospongia australis 25:694 Polyfibrospongia sp. 19:577 Polygala fruticosa 7:415;23:342 Polygala polygama 17:341 Polygala senega 21:666 senegasaponins from 21:666 Polygalacic acid 21:634 Polygalactosamine-galactan 23:109 Polygalacturonase 25:374 Polygalacturonides 25:486 Polyglucuronic acid 23:109 1,4-[3-Polyglucuronide 14:254 Polyglycosyl ceramides 10:459 Polygnum cuspidatum 27:405 for hyperlipidaemia 27:405 Polygodial 1:467,468;2:278,279,286, 289;6:108;7:103,110,121-123; 17:235,244;21:608,610,618,619; 22:612;26:461 ;29:87;30:193,206 activity in EBV assay system 29:87 activity in Skin 1 assay system
649 29:87 activity in CRG assay system 29:87 activity in CRO assay system 29:87 activity in AA assay system 29:87 activity in BRK assay system 29:87 activity in CPS assay system 29:87 activity in HTM assay system 29:87 activity in PAF assay system 29:87 antinociceptive action of 30:206 chiral synthesis 1:701,702 piscicidal activity of 2:289 from thujone-derived synthons 14:413-421 Ju-Fang synthesis of 6:14 piscicidal activity of 2:289 synthesis of 14:413-421 Yu-Lin-Wu synthesis of 6:14 (+)-Polygodial 6:13 by Ley's procedure 6:13 Ju-Fang synthesis of 6:14 synthesis of 6:13,14,19,125 Yu-Lin-Wu synthesis of 6:14 Polygonaceae 22:634 Polygonal 22:612 Polygonaquinone 22:610,611 Polygonati rhizoma 21:668 14a-OH-diosgenin from 21:668 Polygonum auberti 22:607,608,609, 613,614,615,621 Polygonum avaculare 22:614,632 Polygonum bistorta 22:118,119,632 Polygonum caepitosum 22:633 Polygonum chinense 22:614 Polygonum conspicum 22:632,634 Polygonum coriavium 22:614 Polygonum culiinerve 22:609 Polygonum cuspidatum 22.'607,608, 609,611,633,637;27:854;30:340 anthraquinone emodin from 30:340 for hyperlipidaemia 27:405 Polygonum debile 22:632
Polygonum dumetorum 22:633 Polygonum ellipticum 22:610 Polygonumfalcatum 22:610 Polygonumfilliforme 22:615,632,634 Polygonum glabrum 22:614 Polygonum hydropiper 7:100,101,103,
110,121;17:237;21:608;22:612,614, 633,634,635;29:87 Polygonumjaponicum 22:633 for convulsions 22:530 Polygonum lapathifolium 22:633 Polygonum longisetum 22:633 Polygonum maackianum 22:632 Polygonum multiflorum 22:610,633 Polygonum nakai 22:633 Polygonum napalense 22:632,634 Polygonum nodosum 7:427;22:614,615 Polygonum orientale L. 22:632;29:579, 580 Polygonum panjutinii 22:611 Polygonum pensylvanicum 27:837 Polygonum perfoliatum 22:632 Polygonum persicaria 22:633 Polygonum plebejum 22:6.12 Polygonum pubescens 22:633 Polygonum sachalinense 22:608,609, 610,620,633 Polygonum sagittatum L. var. Sieboldi 22:632 Polygonum senegalense 7:427;22:614 Polygonum senficosum 22:632 Polygonum sp. 22:460;27:405;28:579; 29:581 biological activity of 27:405 Polygonum suffultum 22:632 Polygonum tenuicale 22:632 Polygonum thunbergii 22:466,632 Polygonum tinctorium 22:612,633 Polygonum virginianum 22:615 Polygonum viviparum 22:632 Polygonum werichii 22:633 Polygraphus poligraphus 27:370 Polygyala gazensis 26:204 eudesmin from 26:204 kobusin from 26:204 magnolin from 26:204 yangambin from 26:204 Polyhistidine 25:337 Polyhydroxy steroids 23:159
650
Polyhydroxy sterols 5:410;23:177 Polyhydroxydihydro-13-agarroduran 23:663 examples of 23:663 sesquiterpene skeletons of 23:663 Polyhydroxyindolizidines 12:275; 27:252 biological activity of 27:252 Polyhydroxylated 2-phenylnaphthalenes 30:225 effect on 5-1ipoxygenase inhibition 30:225 Polyhydroxylated phytohormone brassinolide 25:414 Polyhydroxylated steroids 23:159 3fl,5a,6a, 15a-Polyhydroxylated steroids 25:872 Polyhydroxy-p-terphenyl 29:295-298 biosynthesis of 29:295-297 synthesis of 29:298 Polyhydroxysteroids 15:72-76 Polyhydroxyterphenyls 29:300 synthesis of 29:300 Polyketide 7:266 Polyketide antibiotics 5:589,601,613 biosynthesis of 5:598 Polyketide biosynthesis 5:613 Polyketide methodology 11:130,131 (+)-semivioxanthin synthesis by 11:130,131 Polyketide pathway 21:196,203,213 metabolities derived from 21:196,203,213 Polyketide sulfates 7:266 of Comantheriaperplexa 7:266 of Comatualpectinata 7:266 Polyketide synthase 25:502 Polyketides 13:664;24:1050 aromatic natural products 11:113-149 biosynthesis of 11:191-207 cytotoxic effects of 24:1055, 1085 synthesis of 18:155-192 Polylactosaminoglycans 10:461,486 Polymastia boletiformis 25:704;28:704 Polymastia sp. 18:716
Polymastiamide A 28:704 as antimicrobial steroid 28:704 Polymastiamides 25:704 Polymer 17:646 semi-synthesis of 17:646 Polymer support synthesis 4:274, 277-283 protecting groups 4:276 protocol for oligonucleotide synthesis 4:288 Polymer supports 3:82,83 for macrocyclization 3:82,83 Polymerase activity 25:826 Polymerase chain reaction (PCR) 30:384,843 Polymerization 27:760 of dihydrodiconiferyl alcohol 27:760 of guaiacylglycerol-[3-Oconiferyl alcohol 27:760 ofcinnamyl alcohols 27:760 ofconiferyl alcohol 27:760 ofp-coumaryl alcohol 27:760 ofsinapyl alcohol 27:760 of pinoresinol 27:760 Polymixin B 12:387 protein kinase inhibitor of 12:387 Polymorphic S locus 25:386 Polymorphonuclear leukocytes 25:432 Polymorphonucleated neutrophil (PMN) 23:345 Poly-N-acetyllactosamine 10:477 by regioselective [3-glycosylation 10:477 synthesis of 10:477 Polyneuridine 5:74,75,124;9:171 Polyodiumformosanum 24:256 Polyodium nipponica 24:256 Polyodium vulgare 24:256 Polyol ingenol 25:242 Polyols 9:267 Polyorchis penicillans 9:493,494 Polyoxin C 1:399-400 synthesis of 1:399-400 Polyoxins 1:404;22:63;23:343 antifungal action of 1:399 chitin synthetase inhibition by 1:399
651
Polyozellus multiplex 29:277
Polyphagous lepidopteran 26:871 Polyphenol assay 21:524 Polyphenol oxidase inhibitors 21:587 Polyphenoloxide (PPO) 25:657 Polyphenols 7:409;17:421,427-429; 28:177,257,293 ;30:224,226,227 anti-atherosclerotic activity of 28:257,293 anti-carcinogenic activity of 28:257,293 anti-inflammatory activity of 28:200,257,293 anti-microbial activity of 28:257,293 anti-oxidant activity of 28:257,293 anti-HIV activity of 30:226 antiinflammatory activity of 30:224 antimitotic activity of 30:224 anti-tumor activity of 30:224 antiviral activity of 30:224 anxiolytic activity of 28:177 as anti-HIV agents 30:227 biological activities of 30:224 Polyphenols acteoside 25:476 (+)-ampelopsin 25:476 curcumin 25:476 (-)-epigallocatechin gallate 25:476 gomisin A 25:476 hovenin I 25:476 lithospermate B 25:476 tetrahydroswertianolin 25:476 naringin 25:476 Polyphenyl oxidase (PPO) 23:786 Polyphenylalanine synthesis 7:386 Polyphosphoric acid cyclization 1:58 Polyphosphoric acid trimethyl silyl ester (PPSE) 12:377 Polypodine B 25:59 Polypodium glycyrrhiza 15:28;21:674; 27:16,32 polypodoside A from 27:16,32 polypodoside B from 27:16,32 steroidal saponin from 21:674 Polypodium vulgare L. 15:28;27:16; 29:10
osladin from 27:16 Polypodogenin 15:28 Polypodoside A 27:16,32 structure of 27:32 Polypodoside B 27:16,32 structure of 27:32 Polypodosides A and B 15:27 Polyponus circinatus 5:288,308 Polyporic acid 29:265,298 antibacterial activity of 29:265 as antileukemic principle 29:265 dimethoxy derivative of 29:266 effects on dihydroorotate dehydrogenase enzyme 29:266 effects on lipid peroxidation 29:266 synthesis of 29:298 Polyporus betulinus 5:288 Polyporusfomentarius 5:289 Polyporus giganteus 5:288 Polyporus igniarius 5:289 Polyporus leucomelas 29:277 Polyporus nidulans 29:265 Polyporus rutilans 29:265 Polyporus tumulosus 5:288,290 Polyprenols (dolichols) 8:68-114 as antiinflammatory agents 8:64 NMR spectroscopy of 8:97 synthesis of 8:68-114 Polyprenyl diphosphate sugars 8:63,64, 68-106 deacetylation of 8:88 from phosphorobenzimidazolidate 8:90 from phosphoroimidazolidates 8:89,107,108 synthesis of 8:68-70,86-92 Polyprenyl monophosphate sugars 8:82 from glycosylcation 8:82 from glycosyl-oxyanion 8:83 from phosphoroamidates 8:80, 81,107 synthesis of 8:68,69,82-86 synthesis with prenyl cation 8:69 synthesis with prenyl halides 8:69 synthesis with tosylates 8:69 Polyprenyl phosphates 8:70,71 from prenyl trichloroacetimidates
652
8:70,71 synthesis of 8:68-72 Polypropionates 17:25,26;18:155 Polyquinane 13:39 Polyquinane terpenes 3:117-124 synthesis of 3:117-124 Polyradiculitis 22:584 Polyrhaphin A 17:12 Polysaccharide gums 29:543 in adhesives 29:543 in beverages 29:543 in personal care produts 29:543 in pharmaceuticals 29:543 processed foods 29:543 Polysaccharides 5:275-340;7:31-33, 72 ;8:315 ;9:296,297 ;23:163 ;24:540, 541,1003-1004,1009,1077 antigenicity of 19:689-745 as antitumor agent 5:315 as antiviral compound 24:540, 541 as cell-surface antigens 5:322 enzymatic activity 24:10031004,1009,1077 structural features of 23:163 Polysaccharidic molecule 30:395 as virus inhibitor 395 Polyscias 7:435 Polyscias dichroostachya 21:660 Polysialoglycoprotein 11:429 of rainbow trout eggs 11:429 Polysiloxanes 13:327 synthesis of 13:327 Polysine 25:334 Polysiphonia lanosa 4:712 Polystyrene latex particles 25:270 Polysubstituted 7-oxabicyclo [2.2.1] heptan-2-ones 14:179 Polysubstituted anthracenes 11:120 Polysubstituted dihydropyrans 10:340 from enolate Claisen rearrangement 10:340 synthesis of 10:340 Polysyncaraton lithostrotum 25:837; 28:645 Polytheonamide B 25:715 Polytheonamides 26:1193 Polytomella coeca 2:294 Polyunsaturated fatty acids 27:59,62,67
Polyurethane 7:92 1,3-[3-Polyuronide 14:254 Polyvinyl chloride 22:375 Pomeranz-Fritsch isoquinoline synthesis 129 Pomeranz-Fritsch reaction 16:510 Pomiferin A 20:665 from Salvia pomifera 20:665 Pomiferin GA 20:665 from Salvia pomifera 20:665 Ponaras reagent 13:16 Ponasterone-A 26:700 Ponasteroside 26:700 Poncirus trifoliata 29:579 Pondorf-Meerwein-Verley method 17:605 Ponera pennsylvanica 5:224,230,254 Ponerinae 6:421 Pongamia glabra 22:530;29:771 for epilepsy 22:530 Pongamia pinnata 28:401 Ponicidin 15:174 from Rabdosia rosthornii 15:174 from Rabdosia rubescens 15:174 from Rabdosia ternifolia 15:175 Poniciretin 25:618 Pontevedrine 3:439,440 synthesis of 3:439,440 Pontiatriene 7:221 Pontoneureins A and B 25:801 Populus balsamifera 29:605 Populus deltoides 29:605 Populus maximowiczii 20:627 Populus tremuloides 26:358;29:605 Populus trichocarpa 29:605 Poracantholide I,J 6:544 absolute configuration of 6:544 synthesis of 6:542-544 Porania pulvillus 7:298 poranoside A from 7:299,301 Poranoside A 7:299 from Porania pulvillus 7:301 Poraster superbus 7:299 Porcine pancreatic lipase 16:664 Porcine spleen 12:390 by K-252a 12:390 protein kinase in 12:390 Porcirin 25:618 Porella cordeana 20:469
653
Porella perrottetian 2:280 Porella sp. 2:90 Porfiromycin 13:433 synthesis of 13:440 Porfiromycin 23:81 from Streptoverticillium ordum 13:433 synthesis of 13:440 Poria cocos Wolf 5:288;22:120;25:956 Poricoci acid 25:64 Poricoci acid A 22:122;25:57 Poricoci acid B 22:122;25:57 Porifera 21:3 Poriferasterol 9:399;16:323,332;23:638 Porlieria chilensis 22:352;26:249 dihydroguaiaretic acid from 26:249 guayacasin from 22:352;26:249 isopregnomisin from 22:352; 26:249 Porninsal 17:155 Poronia piliformis 21:197 Porphobilinogen (PBG) 9:591-593 isolation of 19:173 Porphyrin complexes 25:354,355 Porphyrins 25:327,338,340,359,361; 27:745 Porphyromonas gingivalis 23:536 Porson 17:371 ;26:895 Porter's reagents 21:516 Porteresia coarctata 7:189 Porthetria dispar 19:481 Portieria hornemannii 23:342;25:702, 767;26:809 Portulaca oleracea 22:360 13-carotene from 22:360 Positional isomers 29:378 allocolchicinoids total synthesis of 29:378 Post translational modification 25:367 "Post-malonate" exchange process 11:193 Potamogeton sp. 26:361 Potassium ferricyanide 22:204,211 Potassium graphite (CsK) 11:366,367 Potassium hexamethyldisilazide (KHMDS) 24:22-25,42,43 Potassium hydroxide 22:204
Potassium kojate 12:261 O-alkylation of 12:261 Potassium tri (seco-butyl) borohydride 1:261 Potato carboxypeptidase inhibitor 29:596 GM7 as 29:596 Potato disc bioassay 9:399,401,402 Potato discs 9:399 crown gall tumors on 9:399 Potato multicystatin PMC proprotein 29:593 effects on papain PMC 29:593 Potato tubers 28:259 in gallic acid 28:259 in protocatechuic acid 28:259 in salicyclic acid 28:259 n syringic acid 28:259 in vanillic acid 28:259 Potato type I serine protease inhibitors 29:607 Af4 gene product as 29:608 amaranth trypsin inhibitor (AmTI) as 29:607 Arabidopsis genes encoding- 8 potato type 1 serine protease inhibitors as 29:607 ASI-I as 29:609 BGIA as 29:608 Bm7 & Prl0 as 29:608 BTI-1 & BTI-2 as 29:608 BWI-1 as 29:608 BWI-3c; BWI-4c as 29:608 BWI-4a as 29:608 CI- 1a & CI- lb as 29:608 CI-lc 29:608 CI-2 29:608 CMTI-V as 29:608 DI-1 as 29:608 effects on activated Hageman factor (XIIa), trypsin 29:608 effects on bacterial subtilisin-like proteases 29:608 effects on cathepsin G 29:607 effects on chymotrypsin 29:607609 effects on factor XIIa 29:607 effects on Glu-specific protease 29:608
654 effects on plasmin 29:607 effects on serine protease 29:609 effects on Streptomyces griseus glutamate endopeptidase 29:608 effects on subtilisin 29:607,609 effects on BPN' subtilisin 29:607 effects on Carlsberg subtilisin 29:607 effects on Streptomyces alkaline 29:607 effects on protease 29:607 effects on Aspergillus protease 29:607 effects on proteinase K 29:607 effects on Bacillus protease 29:607 effects on pronase 29:607 effects on trypsin 29:608 effects on chymotrypsin 29:608 effects on cathepsin G 29:608 ERI as 29:608 from Amaranthus caudatus 29:607 from Amaranthus hypochondrionacus 29:607 from Arabidopsis thaliana 29:607 from Canavalia lineata 29:607 from Cucurbita maxima 29:608 from Fagopyrum esculentum 29:608 from Hordeum vulgare 29:608 from Linum usitatissimum 29:608 from Lycopersicon esculentum 29:608 from Momordica charantia 29:608 from Nicotiana glauca x N. langsdorffii 29:609 from Nicotiana sylvestris 29:609 from Nicotiana tabacum 29:609 from Sambucus nigra 29:609 from Viciafaba 29:609 from Vigna (Phaseolus) angularis 29:609 from Zea mays (corn) 29:609 GTI as 29:609
LUTI as 29:608 maize protease inhibitor as 29:609 MCI-3 as 29:608 NSTI-I as 29:609 PI-I variant as 29:609 P I-I variants A, B, C & D as 29:609 PIN1 as 29:609 pumpkin fruit trypsin inhibitor as 29:608 Sambucus SPI as 29:609 subtilisin inhibitor as 29:607 TI-1 as 29:608 Vicia PI-I as 29:609 Potato type II serine protease inhibitors 29:610 ARPI as 29:610 aubergine as 29:611 CEVI57 as 29:610 6-domain PI precursor NaProPI (NaPI II) as 29:610 4-domain PI-II precursor NaPI IV as 29:610 effects on chymotrypsin 29:610 effects on pronase 29:610 effects on Streptomyces griseus proteinase B 29:611 effects on trypsin 29:610 from Capsicum annuum 29:610 from Lycopersicon esculentum 29:610 from Nicotiana alata 29:610 from Nicotiana glutinosa 29:610 from Nicotiana tabacum 29:611 from Solanum americanum 29:611 from Solanum melongena 29:611 from Solanum tuberosum 29:611 PCI-I as 29:611 Pepper leafPIs as 29:610 PI-II as 29:611 PI-II K as 29:611 PI-II precursor PI2-1 as 29:611 PI-II precursors NGPI-1 as 29:610 PI-II variants B, C & D as 29:611
655
Pin2-L as 29:611 Pin2-R as 29:611 PSI- 1.1 as 29:610 PTI as 29:611 SaPIN2a & SaPIN2b as 29:611 Potato viruses 30:412 antiviral activity against 30:412 Potato-saponin 25:319 a-chaconine 25:319 Potentilla tormentilla 21:542 Potentillin 23:397 Pothomorphe peltata 22:356 uses of 22:356 Pothomorphe spp. 22:357 Pothomorphe umbellata 22:356 Pothos scandens L. 22:530 for convulsions 22:530 Potier's synthesis 14:869-873 of vinblastine 14:869-873 Potomogeton nodosus 25:260 Potyalthia macropoda 25:260 Polyphenol 22:344 Powdered garlic 23:465 PP inhibitors 25:521 PP1 inhibitors 25:543 PP2A inhibitors 25:543 pp60v-src protein tyrosine kinase inhibition activity 28:698 ofhalistanol sulfate 28:698 (PPL) (pig pancreatic lipase) 13:54,55 PPO activity 25:656 PPO cytochemistry 25:654 PPO phenolic compounds 25:656 PPSE 1:15 for cyclization 1:15 PQQ (Pyrroloquinoline quinone) 1:170-172 synthesis of 1:170-172 Pradimicin A 22:62;23:343 Praeterienolide 27:554 Pramanicin 21:196;28:149,150 as antifungal agent 28:149 Prasinophyceae 6:134,147 Pratylenchus 26:432 Pratylenchus coffeae 26:436 Pratylenchus curvitus 26:477 Pratylenchus neglectus 26:464 Pratylenchus penetrans 26:429, 436-438,449,473,477,481
Pratylensus scribneri 26:472 Pravachol 22:251,252 Pravastatin 13:598;15:450 Prazosin 8:395 Preakuammicine 1:31-35 Precapnelladiene 3:89-91 ;6:33,34; 22:210 by enone-alkene photocycloaddition 6:33,34 from Capnella imbricta 6:33 from triquinane 6:33,34 synthesis of 3:89-91 ;6:33,34 (+)-epi-Precapnelladiene 6:34,35 by Baeyer-Villiger oxidation 6:34,35 by endo-Diels Alder reaction 6:3,34 by intramolecular photocycloaddition 6:34,35 by Sharpless oxidation 6:34 by Wittig olefination 6:33,34 synthesis of 6:33-35 Precipitation technique 13:647 Preclathridine A 17:18 Preclavulone A 8:140 Preclinical development 21:176,177 of A.D.E.P.T. 21:176,177 of benzylcarbamate prodrug HMR1826 21:176,177 of HMR1826 21:176,177 of P.M.T. 21:176,177 Precocene I 2:126,127;4:395,397,398 synthesis of 4:395,397,398 Precocene II 26:471;4:395,397,398 synthesis of 4:395,397,398 Precocenes 22:395 Precondylocarpine 1:31-33,40 Precorrin-N 9:597 Precorrins 1-8 9:597,598,600-604,607 Precyclospongiaquinone-I 15:298 Predator mites 28:434 as pathogen 28:434 Prednisolone 9:411,419-421 (20R)-5a-Pregn-9(11)-ene-3 [3,6c~,20triol (asterogenol) 7:288,291 Pregnane steroids 21:308 Pregnanes 24:289 17(20) Z/E-Pregnenes 10:59 ene reaction of 10:59
656
Pregnenolone 5:711;10:68;16:322; 21:309;25:419 from chloesterol catabolism 5:709 Pregomisin 26:244,247 as PAF-induced inhibitor 26:244 Prehispanolone 25:273 effect on B cell proliferation 25:273 Prelissoclinamide 1 25:880 Prelissoclinamide 2 25:880 Prelog-Djerassi lactone 3:225-257; 10:423 synthesis of 3:227,255-257; 16:711 Prelog-Djerassi lactonic acid 14:267 synthesis of 14:267 Premaxillary dysgenesis 23:571 Premna oligotricha 25:257 Prenyl bibenzyls 2:283,285,286 distribution in Radula sp. 2:286 Prenyl bromide 4:382-387,389,398 C-alkylation of phenolates with 4:382-386 with Diels-alder adduct 4:388, 389 with 3,4-dihydroumbelliferone 4:398 with 5,7-dihydroxyisoflavone 4:382,385 with 2,6-dimethoxy-4hydroxyacetophenone 4:386, 387 with noreugenin 4:382-384 with umbelliferone 4:385,386 7-O-Prenyl coumarin 4:385,386 from umbelliferome 4:385,386 Prenyl diphosphates 7:322 from mevalonic acid 7:322 Prenyl monoesters of 8:33 Prenyl substituents 27:929 Prenyl transferase 7:96,108,323,324, 348 Prenyl transferase reactions 7:321 Prenylated benzophenones 4:375,379 in Visima decipiens 4:378 Prenylated bichalcones 29:777 configuration of 29:777 dihydrochalcone as 29:779
dorstenone as 29:777 flavanone as 29:779 isobavachalcone as 29:778 structure of 29:778 Prenylated biphenyl 4:389 synthesis of 4:389 Prenylated chalcone 27:928 from hops 27:928 Prenylated coumaric acids 30:730 structure of 30:730 Prenylated flavones 29:783 8-prenyl-6,7-(2,2-dimethyldihydro-p yrano)- 5,3 ', 4 'trihydroxyflavone as 29:785 Prenylated flavonols 29:793 6, 8-b &-(3,3-dime thylallyl)5,7,4 '-trihydroxy- 3 'methoxyflavonol as 29:793 3,5,7,3 '-tetraoxygenate d flavonoids as 29:793 para-Prenylated phenol 4:375,376 Prenylated phenolic compounds 4:367-402 synthesis of 4:36%402 Prenylated xanthones 7:410,411,423 a-mangostin 25:541 y-mangostin 25:541 Prenylation methods 4:367-402 by alkali metals 4:386-400 by chromanes 4:394-396 by Friedel-Crafts alkylations 4:391,394 by organometallic reactions 4:396,398 by silver oxide method 4:386 by trimethylsilyl intermediates 4:394 in basic media 4:386-391 of 2,6-dihydroxy-4-methoxyacetophenone 4:386,387 of 1,3-dimethoxybenzene 4:89 Prenylcitpressine 13:350 from Citrus grand& 13:350 6-Prenyleriodictyol 28:229 biological activity of 28:229 8-Prenyleriodictyol 28:229 biological activity of 28:229
657
8-Prenylflavanone 4:378,380 from 7-hydroxyflavanone 4:378,380 6-Prenylflavanone 4:378,380 from 7-hydroxyflavanone 4:378,380 Prenylflavones 28:225;30:207 anti-human immunodeficiency virus (HIV) activity of 28:226 antinocicieptive effect of 30:207 Prenylhydroquinone 5:440;10:248 2-Prenyljuglone 4:388,389 synthesis of 4:388,389 Prenyl-naphthoquinone lapachol 29:719 antibacterial activity of 29:720 anticancer activity of 29:720 antifungal activity of 29:720 antitrypanasomal activity of 29:747 antitumor promoting activities of 29:720 as cytomegalovirus protease inhibitors 29:720 as photosensitizer 29:739 biological activities of 29:719 derivatives of 29:740 from lawsone 29:719 identification of 29:719,722 interconversion of 29:721 isolation of 29:722 [3-1apachone as 29:720 metal complexes of 29:739 paphthoquione derivatives as 29:720 reactivity of 29:736 structural elucidation of 29:719 synthesis 29:719 use in cancer 29:720 use in colds 29:720 use in debilitating 29:720 use in diabetes 29:720 use in dysentery 29:720 use In fevers 29:720 use an flu 29:720 use in gastro-intestinal problems 29:720 use in Hodgkins disease 29:720 use in infections 29:720 use in lupus 29:720
use in osteomyelitis 29:720 use in Parkinson's disease 29:720 use in psoriasis 29:720 use in respiratory problems 29:720 use in skin ulcerations 29:720 use in syphilis 29:720 Prenyl-naphthoquinone lapachol 29:719 Prenylnaphto- 1,2-quinone 27:851 6-Prenylnaringenin 28:229 biological activity of 28:229 8-Prenylnoreugenin 4:382,384 from noreugenin 4:382,384 4-Prenyloxycoumarin 4:375,376 7-Prenyloxyflavanone 4:378,380 from 7-hydroxyflavanone 4:378,380 (+)-Prenylpiperitol 26:267 (-)-Prenylpluviatilol 26:267 Prenyl-protein transferases 24:408,409 Prenylquinone 10:248 N-Preotected or-amino aldehydes 4:122114,117,118,125-127,130 in L-alaninal 4:127 synthesis by oxidative methods 4:113,114 synthesis by reductive methods 4:114 asymmetric synthesis 4:117,118 Prep ANP 25:381 Preparation 10:414,415;23:57,60,84 of (+)-6-epi-ot-cyperone 10:408 of (cQ-terpineol 11:307,308 of 2,2-di-C-methyl-3-deoxy-4ulose 10:414,415 of 2,3-unsaturated allyl glycoside 10:420 of 2-indolyl acetaldehyde 11:315,316 of a building block 11:307,308 of acyclic c~,~-dialkylated ester 10:411 of aristotelin- 19-ol 11:312 ofaristotelin-19-one 11:312 of 4-acetoxy-[3-1actam 12:160-162
658
of 3-acetyl-2-oxazolone 12:411, 415 of 2-axazolone 12:411,415 of chiral auxiliaries 12:416-418 of chiral building blocks 13:73-84 of C-methylated hexopyranose 10:414,415 of diastereomeric aminonitrile 10:126,127 of hexopyranose derivatives 10:426-428 of indolo-[2,3-a] quinolizidine 14:704-706 of indoloquinolizidine enamines 14:727 of indoloquinolizidine Nb-metho salt 14:718,719 of indoloquinolizidine Nb-oxides 14:711-714 of low-valent-titanium reagent 11:364 of monofluorinated chiral building blocks 13:81 of nonulosonic acid 11:466 ofoctulosonic acid 11:466 of Oppolzer's chiral auxiliary 11:307,308 of rifamycin S 23:57,60,84 of sulfoxides 14:517-519 of tetrahydropyrazinone 10:138-140 of titanium trichloride 11:364 of [3-hydroxybutanoic acid ester 10:410 titanium (0) 11:366,367 with zinc/copper couple 11:364 Prepatellamide B formate 25:879 Prephenic acid 11:188 formation of 11:188 Prephytoene diphosphate 7:325-327 phytoene from 7:325-327 Prepinnaterpene 6:9,10 from Laurencia pinnata 6:9 from Laurencia subopposita 6:9 synthesis of 6:9,10 Preproproteins 25:400 Prepsammaplin A 25:844,845 Prepsammaplin B 25:844,845
Prepsammaplin C 25:844 Prepsammaplin D 25:844 Preseychellogenin 15:91 Presilphiperfolan-9-ol 9:535 Presqualene diphosphate 7:325 squalene from 7:325 Prestegane B 26:192,249,269 Pretaxoids 20:107 Pretazettine 15:135;21:97 from Amaryllidaceae 4:3,4 from haemanthidine 4:17 physiological properties of 4:13 retrosynthesis of 4:3,4 synthesis of 4:17,20 Preulithiacyclamide 25:879 Preurogen (hyroxymethylbilane) 9:591, 592,596 Preussia isomera 21:209 thepreussomerins from 21:209 Preussomerins 24:447-449 structures of 24:447 Previtamin D derivatives 30:486 thermal isomerization of 30:486 Previtamin D-form 9:515 Prevost reaction 5:189;14:853,858 Prexylisoflavones 27:844 (-)-Prezizaene 10:410 synthesis of 10:410 Prezizaene 15:248 synthesis of 15:248 (-)-Prezizanol 10:410;15:248 synthesis of 10:410;15:248 Prianicin-A 9:15 Priano melanos 25:822;28:685 Priano sp. 9:15;25:760,822 muqubilin from 9.I5 Prianosin A 25:823 Prianosins C and D 25:823 Prianosinsdischabdins 25:802 Prickles 27:59 as plant protecting organs 27:59 Primaquine 22:150;25:349,350;26:836 Primary biliary cirrhosis 25:463 Primary granulosa cells 25:269 apoptosis in 25:269 Primary hormone 27:321 Primary solid-tumor growth 30:64 effect of triterpenoids on 30:64 Primin 9:338
659
Primula denticulata 5:211 Primula obconica 7:427 Primula viscosa 20:740 Primulagenin A 9:400 cis-Principle 4:584,585 in Diels-Alder reactions 4:584, 585 Prins cyclization 18:174 Prins reaction 13:41,42;18:882,891 (-)-Prinsepiol 26:200,270 Prionitin 5:31 APT spectrum of 5:31 ~3C-NMR spectrum of 5:31,32 COSY spectrum of 5:31,32 CSCM 1D spectrum of 5:31,32 ~H-NMR spectrum of 5:31,32 INEPT spectrum of 5:31,32 NOE spectrum of 5:31,32 Prions 24:482 Pristimarin 30:692 cytotoxic activity of 30:692 Pristimera grahamii 23:659 Pristimeria indica 30:664 celastrol from 30:664 pristimerin from 30:664 Pristimerin 7:147-152;18:757,760,765, 776,77823:709;26:813,814 PRL1 & PRL2 proproteins 29:592 effects on cysteine protease 29:592 Proacaciaside-I 23:498 Proacaciaside-II 23:498 Proansamycin 23:54 Proansamycin B-M1 23:65 Proansamycins A,B 9:439,440,443 Proanthocyanidin dibenz [b,d] oxocin 15:347 L-[U-C 14] Proline 15:347 Proanthocyanidines 24:799 Proanthocyanidins 15:33,34;21:497, 501,502,500,511,515,516,517,518; 22:644,663 ;25:666;26:672;27:35, 37,893;28:278,292 in apples 28:278 in grapes 28:278 in pears 28:278 in strawberrys 28:278 structure of 27:37;28:278 Pro-apoptopic 27:851
Proaporphine dienones 2:259 correlation between specific rotation and absolute configuration 2:259 Proaporphines 2:251-259 absolute configuration of 2:253 stereochemistry of 2:253 Probes 27:332 activity of 27:346 for 7',7'-difluoro-ABA 27:348 for 7'-hydroxylation 27:348 for 8'-hydroxylation 27:346 for ABA receptors 27:332 for abscisic acid receptors 27:330 for determining the abscisic acid reception 27:331 for isomerization to phaseic acid 27:348 for structure activity relationship 27:332 ofabscisic acid 27:332 Probit-graphic interpolation method 25:47 Procambarus bouvieri 19:665 Procambarus clarkii 19:627 Prochiral carbonyl groups 4:332,333 asymmetric addition to 4:332, 333 Prochiral ketones 1:689 chiral alchohols from 1:689 reduction with yeast 1:689 Prochiral naphthalene rings 4:332 asymmetric additions to 4:332 Prochiral sulfides 14:517,518 asymmetric oxidation 14:517, 518 Prochloron 10:243 Procumbide 7:477 Procurcumenol 29:90 activity in TNFcz assay system 29:90 Procyanidin 25:544;26:697;29:585 effects on LELA 29:585 Procyanidin A2 21:505 Procyanidin B1 21:505,534,535,539; 29:580 effects on ACE 29:580
660
Procyanidin B2 21:522,526-528,534, 540,545,548,553 ;22:663 ;29:580 effects on ACE 29:580 Procyanidin B-2 3,3'-di-O-gallate (condensed tannin) 29:580 effects on ACE 29:580 Procyanidin B3 21:528,535 Procyanidin B4 21:522,523,539 Procyanidin B5 21:527,528,535 Procyanidin B-5 3,3'-di-O-gallate 29:580 effects on ACE 29:580 Procyanidin C1 21:534,527,528,534, 545,553 Procyanidin C2 21:528,535;29:580 effects on ACE 29:580 Procyanidin dimer 25:541 Procyanidin glycoside 25:594 Procyanidin polymer (flavan-3-ol polymer) 29:580 effects on ACE 29:580 Procyanidin, O-glycosides 21:499 Procyanidins 21:497-557 analysis of 21:497-557 quantitative analysis of 21:507qualitative analysis of 21:507Procyanidins (polyphenolic oligomers) 29:582 effects on collagenase 29:582 Procyanidins B6 21:535 Prodelphinidins 21:515,545;25:544; 26:697 Prodigiosin 8:272,273 synthesis of 8:272,273 Prodrug monotherapy 21:157 natural anthracyclines for 21:157 Prodrugs 21:157 of natural anthracyclines 21:157 Progesterone 25:139,421 Prognosis 22:56 Proguanil 26:783 Pro-inflammatory cytokines 25:461 Pro-inflammatory substances 30:206 in chronic painful inflammatory diseases 30:206 Projulinine 5:211 Prokaryotes 21:303;27:736 Prolactin (PRL) 25:265 Proleus mirabilis 25:259
Proliferation 30:368,378 effect of serotonergic neurotransmission on 30:368 serotonin action on 30:378 /-Proline 14:555,556 piperidine derivative from 14:555,556 pyrrolidine derivative from 14:555 Proline endopeptidase 2:35 Prolines 4:327;16:603-608;25:320,371, 372 as chiral auxiliaries 4:327 photooxidation of 16:603-608 l-Prolinol 14:743-747 as chiral auxiliary 14:743-747 Prolycopene 7:330-335 Prolysine 25:388 prophylactic effects of 25:429 Pro-nociceptive prostaglandins 30:192 in inflammation 30:192 Pro-nociceptive transmitter 30:194 release inhibition of 30:194 Proothramycins 21:374 Prooxidant activities 30:745 in thiobarbituric acid assays 30:745 of chemiluminescence 30:745 of tert-butyl hydroperoxide 30:745 Prooxidant property 30:524 of carotenoids 30:524 Propacin 5:5,8,497 Propane- 1,3-diols 13:53-105 asymmetric synthesis of 13:53-105 enantioselective 13:53-55 enzymatic 13:55 transesterification of 13:53-55 1,3-Propanediol 8:373,376;14:653 1,3-Propanedithiol 11:357 Propanedithiol 6:301,302 protection with 6:301,302 (S)-Propanolol 6:346,347 synthesis of 6:346,347 (S)-Propargyl alcohol 13:585 Propargyl alcohol 14:569 cis-olefin from 14:569
661
pyrrolidine derivative from 14:569,570 Propargyl alcohol 14:569 cis-olefin from 14:569 pyrrolidine derivative from 14:569,570 9'-Propargyl-abscisic acid 27:348 Propargylic alcohols 14:473 synthesis of 14:473 Propargylic titanium reagent 12:24 from alkyne 12:24 with methacrolein 12:24 Yamamoto condensation of 12:24 Propelargonidins 21:515 [3.3.3]-Propellane 13:3-39 Propellane sesquiterpenes 13:37-39 [m,n, 1]Propellanes 14:490 asymmetric synthesis of 14:490 via asymmetric cyclopropanation 14:490 (E,Z) S-1-Propeny allyl thiosulfinate 23:467 (E,Z)-S- 1-Propenyl methanethiosulfinate 23:467 (R)-(Z)-Propenyl p-tolyl sulfoxide 10:671,672 S -trans-2-Propenyl-~/-glutamylcysteine
23:458 S- 1-Propenyl cysteine 23:464 S-1-Propenylcysteine sulfoxide 23:458 S-2-Propenylcysteine thiosulfinate 23:468 Propenylphenol 5:459,472,473 Prophylactic activity 13:666 Prophylactic drugs 30:407 Prophylactic effect 25:429 of prolysine 25:388 [2-2H2, 2-13C] Propionate 11:196,197 incorporation of 11:196,197 incorporation into erythromycin A 11:196,197 incorporation into erythromycin B 11:196,197 incorporation into lasalocid A 11:196,197 incorporation into monensin A 11:196,197
Propionibacterium acnes 25:463,471 ;
28:534 mononuclear cell infiltration induced by 25:463 Propionibacterium shemanii 9:598,600604;11:182 Propionic acid derivatives 12:163,165, 169 Propionyl CoA 11:195 carboxylation of 11:195 (2S)-methylmalonyl CoA from 11:195 Propiophenone derivative 30:731 structure of 30:731 Propolis 25:945 Propranol 27:394 from glucose 27:394 Proprotein covertase (PC) 25:388,402 Proprotein processing protease 25:392 Propyl 1-thio-[3-D-galactopyranosides 8:315 (1R,6R,TS)-7-(2-Propyl)-4,10-dimethyl-
bicyclodecane 21:282 2-n-Propyl-4-tert-butyl-cyclohexanone 14:645 24-Propylidenecholesterol 9:37 biosynthesis of 9:37 Propylidene-c~-D-ribo-hexafuranose 14:155 2-n-Propylquinoline 26:820,821 Prorhinotermes simplex 19:118 Prorocentrolide 19:617 stereochemistry of 19:617 Prorocentrum 27:875 Prorocentrum lima 5:384,17:20,19:617; 21:301 Prorocentrum maculosum 21:301 Prorocentrum sp. 21:301 5 '-ProS proton 27:338 (+)-Prosafrinine 13:482 Prosafrinine synthesis 29:419 by stereodivergent process 29:419 Prosafrinine/iso-6-cassine synthesis 29:425 of c~,ct'-disubstituted 3piperidinol alkaloids 29:425 Prosapogenin 1 25:209
662
Prosapogenin 2 25:209 Prosapogenin 3 25:209 Prosapogenin 4 25:209 Prosapogenin 5 25:209 Prosapogenin 6 25:209 Prosapogenin A 821 Prosapogenin B 23:821 Prosapogenols 7:268
Proserpinaca palustris 26:359
Prosobranchia 17:3,19;21:3 Prosoflorine 9:72,73,77 (+)-Prosophylline 13:481 Prosophylline synthesis 29:419 by stereodivergent process 29:419 Prosopidione 9:68,69 (+)-Prosopinine 18:347 Prosopinine synthesis 29:419 by stereodivergent process 29:419 Prosopinoline 9:71,77 Prosopis chilensis 28:424 Prosopis glandulosa 29:580 Prosopisjuliflora 5:211 ;9:68-73 ;29:605 alkaloids from 9:70-73,290 terpenoid diketone from 9:68,69 Prosopis sp. 29:420 Prostacyclin 12:399;16:388;22:112, 616,629;25:598 preparation of 16:386 Prostaglandin 1:686,687;5:377, 815-833 ;7:483 ;9:290,559,571; 13:659;17:642; 19:550;24:541-544; 30:192 as antiviral compound 24:541-544 as pain mediator 30:192 anticancer clavulones 16:366 asymmetric synthesis of 4:607 in mast cells 30:192 nociceptive effect of 30:192 synthesis of 16:364-394 A-Prostaglandin 16:366 (+)-(15S)-Prostaglandin A2 10:418 synthesis of 10:418 Prostaglandin analogue 7:479-483 Prostaglandin derivative 2:51 Prostaglandin E 20:534 (-)-Prostaglandin El 19:163
Prostaglandin E2 12:399;21:594 by staurosperine 12:399 production of 12:399 Prostaglandin Ez-dependent flavonoids cytoprotection effect of 25:607 Prostaglandin endoperoxide receptor antagonist 25:593 Prostaglandin F2~ 8:140;10:419 Prostaglandin H2 (PGH2) 25:595 Prostaglandin 12 (prostacyclic) 12:399 by K-252a 12:399 by staurosperine 12:399 production of 12:399 Prostaglandin inhibitors 30:192 clinical use of 30:192 use in rheumatism 30:192 use in osteoarthritis 30:192 use in headache 30:192 use in dental surgery 30:192 Prostaglandin lactones 19:549 Prostaglandin synthetase 5:816,819 Prostaglandin synthetase inhibitors 5:815-833 Prostaglandin synthetase inhibitory activity 21:591 Prostaglandins A2 19:571 Prostaglandins (PGs) 19:162 Prostaglandins E2 19:571 Prostanoids 30:192 formation of 30:192 from arachidonic acid 30:192 Prostanoids from 30:192 Prostate cancer 23:294 Prostate cancer prevention 30:525 role oflycopene in 30:525 Prostoglandin F2 3:227 synthesis of 3:227 Prostoglandin PGA2 3:247 synthesis of 3:247 Prosystemin 25:373,374,375 Prosystemin cDNA 25:370 Prosystemin polypeptide 25:375 Proteacea 9:319,328 Protease 6:551;16:737;30:226,831 chymotrypsin 30:831 earthworm chymotrypsinogen 30:831 F-III-l(2) 30:831 human leukocyte elastase (HLE)
663
30:831 lugworm chymotrypsinogen 30:831 pocine pancreatic elastase (PPE) 30:831 role in HIV 30:226 trypsin 30:831 U(t)-PA, plasmin 30:831 Protease inhibitor proteins from plants 29:596 effects on metallo-carboxy peptidase 29:596 Protease inhibitors 24:487,488;26:800; 29:567 Bowman-Birk as 29:567 cereal bifunctionals as 29:567 chymotrypsin as 29:568 destructive potential of 29:568 in Alzheimer's disease 29:567 in angiogenesis 29:567 in cancer inflammatory disease 29:567 in protozoal infection 29:567 in viral infection 29:567 Kunitz as 29:567 mustard family of 29:567 of metallocarboxypeptidase 29:567 of serine protease 29:567 pepsin as 29:568 phytocystatins as 29:567 potato type 29:567 proteins as 29:567 serpin as 29:567 trypsin as 29:568 Proteases 24:1005;29:567 enzymatic activity 24:1005 in apoptosis 29:567 in blood clotting 29:567 in cell division 29:567 in digestion 29:567 in extracellular matrix digestion 29:567 in inflammatory responses 29:567 in peptide bond hydrolysis 29:567 in protein destruction 29:567 regulation of 29:568
3',5'-Protected adenosine derivative 14:286 2'-phosphorylation of 14:286 N-Protected alaninals 4:121,122 and threo selectivity 4:122 N-O-Protected D-allo-threoninal 4:143 organometallic addition to 4:142 Protected ribonucleotides 4:300 for oligoribonucleotide synthesis 4:300 N-O-Protected or-amino aldehyde 4:130 in cyclocondensation 4:130 Protecting groups 4:299 acid labile 4:299 anilido 4:286 base labile 4:299 benzyl 4:299 2'-O-t-butyldimethylsilyl (TBDMS) 4:299 1-[(2-chloro-4-methyl) phenyl]4-methoxy-piperidin-4-yl (CTMP) 4:299 5-chloro-8-quinolyl 4:286 2-cyano- 1,1-dimethylethyl 4:285 2-cyanoethyl group 4:285 dimethoxytrityloxyethyl sulfonyl ethyl 4:285 for 2'-hydroxyl 4:296 for 5'-hydroxyl 4:297 for internucleotidic phosphate group 4:268 for phosphomonoester formation 4:285 in polymer support synthesis 4:276 p-methoxybenzyl (MBn)) 4:300 3-methoxy- 1,5-dicarbomethoxypentanyl (MDMP) 4:300 methoxytetrahydropyranyl 4:297 (1-methyl- 1-methoxy) ethyl (MME) 4:300 monomethoxytrityloxyethylamino 4:289 o-nitrobenzyl (NB) 4:300,301 p-nitrophenylethyl 4:285 ent-pseudoguaianolide intermediate 4:675 2-(2-pyridyl) ethyl 4:286 tetrahydropyranyl 4:297
664
trihaloalkyl 4:285 3,4,5-trimethoxybenzoyl 4:299 Protection 1:440,442,443;6:284,285; 18:403-421 of alcohol 1:440,442,443 of inositols 18:403-421 with cyclocarbonate group 6:284,285 with lauryl chloride 6:429 with MEM 6:558,559 with methoxyethoxy group 6:298,299 with methoxymethyl group 6:282,283 with O-isopropylidene 6:269,270 with pivaloyl ester 6:264,268 with propanedithiol 6:300,301 with tert-Bu Me2SiOCH2COC1, 1:440,442,443 with tert-butyldimethyl silyl ether 6:264,268 with tetrahydropyranyl ether 6:264,268 Protection/deoxygenation procedures regioselective 14:744 Protection-deprotection reaction 30:461 G-Protein 22:18,19 Protein binding 27:377 Protein biosynthesis 21:97,98 Protein kinase 5:384;23:537 Protein kinase A (PKA) 12:384;30:192 in regulation of ionotropic receptors 30:192 Protein kinase activity 28:677 ofxestoquinolide B 28:677 Protein kinase C 12:233,253,364; 27:822,827,828,830,834 classical forms of 27:822 from Dictyostelium discoideum 12:384 from mammalian cells 12:384 used for anticancer drug design 12:384 Protein kinase C (PKC) activator 30:70 Protein kinase C inhibition 24:573; 25:46,488 by xestocylamine 24:573 Protein kinase classical form 27:822 of glycoprotein 27:737
Protein kinase G (PKG) 12:384 Protein kinase inhibition 30:207 by pentacyclic triterpenes 30:207 Protein kinase inhibitor 23:168,180 secosterols as 23:168,180 Protein kinases 27:826 activity of 27:826 Protein phosphatase inhibitors 25:707;27:872-874 inhibitor of 25:707 Protein phosphate 27: Protein phosphorylation 27:819 by natural products 27:819 biochemical basis of 27:820 Protein S-nitrosylation 26:913 Protein synthesis 30:407 inhibitor of 30:407 Protein transduction domain (PTD) 30:840,844 Proteinaceous polysaccharide 27:511 Proteinaceous receptor 25:371 Proteinase activity 21:150 Proteinases 21:224 Protein-coupled receptor 27:821 GProteine kinase C activity 21:638 Proteins 24:522,527-533,1017 as antiviral compound 24:522, 527-533 Protein-tyrosin~ ",-inase activity 27:842 offlavonoid aglycones 27:842 of glycosides 27:842 ofKoelreuteria henryi 27:842 Protein-tyrosine kinase inhibitory activities 27:839 Protein-tyrosine kinases (PTK) 9:390, 391 inhibition by piceatannol 9:390, 391 Proteolytic activity 30:841 Proteolytic systemin inactivation 25:375 Proteus 12:63 Proteus ganera 29:311 Proteus mirabilis 12:400;20:712,837, 840,842,853,855,858;22:627;26:402, 1155 Proteus vulgaris 9:308;12:103,400; 20:831,837,839,840,859,879;22:627 Prothymosin 8:433-435
665
Protides 24:1016-1018 amino acids derivatives 24:1016, 1017 Protium kleinii 30:206 anti-inflammatory effect of 30:206 antinociceptive effect of 30:207 Protoanemonin 10:149,186 Protoanthocyanidins 22:631 Protoberberine 5:42;22:20,29 Protoberberine alkaloids 1:217,218; 21:84;27:749 from spirobenzylisoquinolines 1:217,218 photochemical formation 1:217, 218 ring D inversion 217,218 synthesis of 1:217-221 Protoberberinephenolbetaines 1:190-192 synthesis of 1:190-192 Protoberberines 14:769-803 synthesis of 3:444-446 Protocatechuic acid 8:295,296;22:609; 23:750,761 ;29:589 effects on PEP 29:589 Protodesilylation 12:322 Protodestannation 1:490 Protodioscin 23:824 Protohypericin 22:646,648,649; 30:607,608 structure of 30:608 Proton pump inhibitors (PPIs) 25:612 Protonated astaxanthin 30:534 delocalisation of 30:534 in crustacyanin 30:534 structure of 30:534 Protonated carotenoids 30:546 bond lengths of 30:546 dipole moments of 30:546 exo-Protonation 4:654,655,657,658 Proton-proton NOE 2:70 Proton-translocating NADH:Q oxidoreductase 28:435 high-affinity inhibitors of 28:435 Protooncogenes 25:47,269 ?'-myc and bcl-2 25:267 Protopanaxadiol glycoside 21:665 Protophyrin IX (PPIX) 25:335,354,355
Protopine 21:68 Protopine alkaloid allocryptopine 25:539 Protopine alkaloids 1:187,189; 6:488-491;21:69 by Hofmann elimination 6:488, 489 dihydrocoptisine conversion to 6:491 from tetrahydroberberine derivatives 6:488,489 from tetrahydroprotoberberine precursors 6:491 Protopine alkaloids N-oxide derivatives 6:494 dibenzo oxazacycloundecine derivatives from 6:494 Protopine N-oxide 6:494 corydalisol from 6:494 hypcorine from 6:494 Protopseudohypericin 22:648;30:607, 608 structure of 30:608 Protoreaster nodosus 7:290,304-306; 15:46,60 5ct-cholestan-313,6a, 8,15et, 1613, 25-hexol from 15:77 nodosocide from 7:295 Protoreasteroside 7:290,293 Protorifamycin 23:54,62 Protorifamycin I 9:440 Protorubradirin 23:54,68,69 methanolysis of 23:69 Protosappanine B 20:276 Protostephanine 6:480;21:769 biosynthesis of 6:480 from 1-benzyltetrahydroisoquinoline system 6:480 in Streptomycesjaponica 6:480 synthesis of 6:478 Protostreptovaricin 21:430;23:54 Protostreptovarlcin group 23:54 Protostreptovarlcin I 23:62,65 Protostreptovaricin II 23:62 Protostreptovaricin III 23:62 Protostreptovarlcin IV 23:62 Protostreptovarlcin V 23:62 Prototimosaponin A 21:111,668 Prototropic cyclization 25:141
666
Protozoa 2:293-319 glycocomplexes of 5:612 Protozoocidal activity 30:329,741,742 against Leishmania 30:329 against Plasmodium 30:329 against Tryponosoma 30:329 genus Baccharis 30:741 in vitro 30:329 of neo-clerodane diterpenoids 30:742 of quinone derivative 30:329 Protozoocidal compounds 30:740 use of 30:740 Protozoocidal neo-clerodane diterpenoids 30:741 structure of 30:741 Protylonolide 5:611-615 Proxiphomin 13:123,125 synthesis of 13:123,125 Proxisomicine A1 22:559 Proxyelocytic leukaemia (HL-60) cells 27:842 Prumysin 23:343 Prunectin 22:446,458,460,495 Prunella vulgaris 29:588;30:401 antiviral activity of 30:401 Prunin 26:745 Prunus avium 23:746 Prunus cerasus 20:721 ;23:746 Prunus domestica 21:506;23:750 Prunus ovium 21:498 Prunus persica 21:503 Prunus sp. 26:1157;29:577 Prymnerium parvum 25:794 Prymnesin-2 25:794,795 Psalliota bispora 13:310,304 Psalliota campestris 5:289 Psamaplin B 25:858 Psammaplin A (bisprasin) 28:693 effects on Bacillus subtilis 28:693 Psammaplysilla 25:833;28:693 Psammaplysilla purpurea 25:719; 28:693 antimicrobial activity of 28:693 as tyrosine kinase inhibitor 28:693 presammaplin A from 28:693 psammaplin B from 28:693
psammaplin C from 28:693 psammaplin D from 28:693 Psammocinia 25:761 Psathyrotes ramosissima 7:427 Pschorr reaction 20:301;16:504 Pschorr-type diazo-couplings 20:301, 302 Pseudaxinyssa 9:38;25:857;28:665 or,c0-bis-isothiocyanates of 28:665 Fijian species of 28:65 e~-isothioc yano-o- formyl analogues of 28:665 Pseudaxinyssa pitys 21:356;25:854; 28:659 farnesyl isothioycyanate from 28:659 Pseudoakuammicine 1:32 (-)-Pseudoakuammigine 9:183 Pseudoarachniotus roseus 21:389 aranorosin from 21:389 Pseudoaspidosperma alkaloids 19:90, 103 Pseudoaspidospermanes 19:105 (+)-20R-Pseudoaspidospermidine 5:123 (-)-20S-Pseudoaspidospermidine 5:125 Pseudobactin (pyoverdins) 9:537-539, 541,547,551,553 X-ray crystal analysis of 9:539 Pseudobaptigenin 22:446 Pseudobases 27:171 disproportionation of 27:174 of sanguinarine 27:174 Pseudoberberine 14:775,776 reduction of 14:775,776 Pseudobersana mossambicensis 20:478 bioactive steroids from 20:476 (+)-Pseudocarpamic acid 13:482 Pseudo-cellobiose 13:213,215,219 Pseudoceratidine 25:785 Pseudoceratina purpurea 25:720,774, 784 Pseudoceratina verrucosa 25:712 Pseudoceretina 25:719 Pseudodilution 3:82,83 Pseudo-disaccharides 13:195,,218,219, 221,223-225,236,238,240,241,244, 246,247
667
synthesis of 13:212-216 Pseudodistoma arborescens 23:264 Pseudodistoma aurum 25:782 Pseudodistoma kanoka 10:249;23:185 Pseudodistomin A 23:188 relative configuration of 23:188 Pseudodistomin B 23:188 relative configuration of 23:188 Pseudodistomin B acetate 23:188 Pseudodistomin C 23:88,187,192 IH-~H-COSY spectrum of 23:187 HSQC spectrum of 23:187 Pseudodistomin C acetate 23:187,188 ~H-NMR of 23:187 HMBC spectrum of 23:187 HSQC spectrum of 23:187 Pseudodistomins 23:185,186 Pseudodistomins A,B 10:249 Pseudodoynerus quadrisectus 5:224, 232 (+)-Pseudoephedrine 12:479,480 synthesis of 12:479,480 d-Pseudoephedrine 18:602 Pseudoerythromycin A 13:159 Pseudoginsenoside 15:191 Pseudoginsenoside RP-1 21:673 Pseudo-gloeosporone 10:220 synthesis of 10:220 Pseudoguaiane 7:209 Pseudoguaiane 11~, 13-dihydrohelenalin acetate 29:90 activity in CRO assay system 29:90 ent-Pseudoguaianolide intermediate 4:675 Pseudoguaianolide sesquiterpenes 1:545,546 Pseudoguainolides 24:72 Pseudoheliotridane 1:242,257 synthesis of 1:258 Pseudohypericin 7:421 ;22:645,647, 664,671,674,687;30:608,627 against cytomegalo virus 30:627 against human immunodeficiency virus- 1 30:627 against influenza virus 30:627 as virucidal agents 30:627 retroviral activity of 7:421
Pseudoindoxyl-type alkaloids 5:102 conopharyngine pseudoindoxyl 5:102 19R-hydroxyibogaminepseudoindoxyl 5:102 ibogaine pseudoindoxyl 5:102 ibogamine pseudoindoxyl 5:102 voacangine pseudoindoxyl 5:102 voacristine pseudoindoxyl 5:102 Pseudo-isomaltose 13:213,215,219 Pseudojujubogenin 23:511,503 Pseudo-laminarabiose 13:213 Pseudolaric acid A 21:754 Pseudolaric acid A-[3-D-glucopyranosylester 21:754 Pseudolaric acid B 13:653;21:754-759; 23:342 antifertility activity of 21:758 antifungal activity of 21:758 as fertility-regulating agent 13:653 synthesis of 21:757 Pseudolaric acid B-[3-D-glucopyranosylester 21:754 Pseudolaric acid C 21:755 Pseudolaric acid E 21:755 Pseudolarin kaempferi 21:654;23:342 Pseudolycorine 21:97 Pseudo-maltose 13:212,213,215,219 Pseudomanas ~yringae 26:583,590592,594,595,598,599,607 Pseudomonas 5:434;9:37;18:429,430; 21:185-187;22:81 ;25:145,146,148, 152,153,155,929;26:69,582,584,588, 597,617,969,1124;1134 papakusterol (glaucasterol) from 9:37 for enantioselective hydrolysis 12:337 Pseudomonas aerginosa 1:370,377; 3:302;5:434 ;9:308,537,540,553,555; 12:63,103,401 ;14:144,236;19:601; 21:610;23:41,235 ;25:133,257,258, 259,394,828;26:330,331,365,402, 1151;30:739 antibacterial activity against 30:739 antifungal activity against 30:739
668
Pseudomonas alginate 26:1151 Pseudomonas amygdali 26:583,587, 590,599 Pseudomonas aureofanines 9:527 Pseudomonas bromopseudilin 21:298 Pseudomonas caryophylli 26:594 Pseudomonas cepacia 4:432;21:205 Pseudomonas cepacia lipase 30:473 in isopropenyl acetate 30:473 Pseudomonas chloroaphis 9:537 Pseudomonas ciccaronei 26:595,599 Pseudomonas cichoriae 9:537 Pseudomonas citronellolis 25:132, 133,165 Pseudomonas clavata 25:836 Pseudomonas convexa 25."133 Pseudomonas coriacea 12:294 Pseudomonas denitrificans 9:600,603, 604,606 Pseudomonas diminuta 26:1155 Pseudomonas eruciviae 25.168 Pseudomonas fluoescens 3:263;9:537; 10:78;21:186,296;25." 152,394;26:78, 333,334 Pseudomonasfluorescens lipase 1:685; 13:54,55 Pseudomonas genus 19:791 Pseudomonas incognita 25:133,140, 141,147 Pseudomonas iodina 27:219 Pseudomonas lipase PSL 13:55 Pseudomonas magnesiorubra 28:115 Pseudomonas maltophilia 4:432 Pseudomonas medicinalis 25:257 Pseudomonas morganii 5:434 Pseudomonas perolens 13:320 Pseudomonas pseudomallei 25.'140 Pseudomonas putida 4:647;8:296,298, 303,305,309 ;9:537 ;13:58,299; 18: 430;25:131,156,661 Pseudomonas sorghi 9:220 Pseudomonas striiformis 9:220 Pseudomonas syringae 4:590;9:537; 25.399,394,398 Pseudomonas syringae pv. Maculicola 26:593,933 Pseudomonas taetrolens 13:320
Pseudomonic acid 10:339 by Claisen rearrangement 10:339 synthesis of 10:339,425 Pseudomonic acid C 3:263-267 synthesis of 3:263-267 Pseudomyrmecine sp. 6:421,422 Pseudo-NANA 13:210 synthesis of 13:210 Pseudonigeran 5:276,280,288 Pseudo-nitzschia multiseries 25.'729 Pseudo-oligosaccharide inhibitors 10:503 Pseudo-oligosaccharides 13:235-246 synthesis of 13:235-246 Pseudopelletierine 21:51 Pseudophrynamines 18:726 Pseudophrynaminol 18:725 Pseudophryne coriacea 725 Pseudophryne genus 19:52 Pseudophryne guentheri 726 Pseudophryne occidentalis 18:726 Pseudoplatanus 25:376 Pseudoplexaura crucis 8:20 Pseudoplexaura flagellosa 8:20 Pseudoplexaura porosa (Plexaura crassa) 8:20 crassin acetate from 8:20 Pseudoplexaura wagenaari 8:20 crassin acetate from 8:20 Pseudopteranes 23:171 Pseudopterasin 15:259;25:689,690 Pseudopterogorgia 23:153 Pseudopterogorgia acerosa 23:154,164, 170,175 Pseudopterogorgia americana 6:18,27, 21:313;23:154,160 (-)-[3-gorgonene from 6:18,27 Pseudopterogorgia bipinnata 23:154, 175,178 Pseudopterogorgia elisabethae 15:259; 23:154;25.'690;29:689 pseudopterosins A-D from 6:74 Pseudopterogorgia hummelinkii 23:154 Pseudopterogorgia kallos 23:154,175 Pseudopterogorgia rigida 23:154,164, 181 Pseudopterogorgia sp. 23:179 biological activity of 23:179 3-epi-Pseudopterosin 15:259
669 Pseudopterosin A 16:214,262 Pseudopterosin E 16:262;25:689 (-)-Pseudopterosin-A 6:74,75 Broka's synthesis of 6:74,75 by Chan-Brownbridge procedure 6:74,75 by Friedel-Crafts alkylation 6:74,75 by glycosidation 6:74,75 by Michael addition 6:74,75 by selenation-oxidation 6:74,75 from (S)-(-)-Limonene 6:74,75 Pseudopterosins 23:154,158,180 synthesis of 23:154,158,180 Pseudopterosins A-D 6:74,75 from Pseudopterogorgia elisabethae 6:74 Pseudopuropurin 26:657,663,666,675 Pseudorabies virus 30:404 in vitro replication of 30:404 role ofheparin 30:404 Pseudostichoposide A 15:94 from Pseudostichopus trachus 15:94 Pseudostichopus trachus 15:94 pseudostichoposide A from 15:94 Pseudosuberites hyalinus 18:696 Pseudo-sugars (carba-sugars) 13:187-255 Pseudotabersonine 5:124 Pseudoterane skeleton 23:170 Pseudo-tetrasaccharides 13:238 Pseudotheonamides A~,A2,B2,C, & D 26. 1194 Pseudo-trehalose 13:213,215 Pseudo-trisaccharides 13:237,238 synthesis of 13:212-217 Pseudotropine 1:383-385 synthesis of 1:383-385 Pseudotsuga menziesii 27:837,838 Pseudovincadifformine 19:103,19:105 P seudovincadifformine-type alkaloids 5:103-105 14,15-anhydrocapuronidine 5:103-105 14,15-anhydro- 1,2-dihydrocapuronidine (+)-capuronidine 5:104
(+)-20R- 1,2-dehydropseudoaspidospermidine 5:104 (+)-20S-hydroxy- 1,2-dehydropseudoaspidosper midine 5:104 (+)-20R- 18,19-dihroxypseudovincadifformine 5:104 (+)- 19-hydro xy- 20-ep i-p ando line 5:105 20-epi-pandoline 5:105 (+)-20R-pseudoaspidospermidine 5:104 (-)-20S-pseudoaspidospermidine 5:104 (+)-20R-pseudovincadifformine 5:105 (+)-20S-pseudovincadifformine 5:105 Pseudovincamines 1:114 Pseudovobparicine 5:125 Pseudoxanthoma elasticum 26:675 (-)-Pseudoyohimban 10:155 Pseudoyohimbine 25:29,30 Pseurata A 15:116 13C-NMR of 15:130 from Rabdosia pseudo-irrorata 15:174 IH-NMR of 15:123 Pseurata B 15:118 13C-NMR of 15:132 from Rabdosia pseudo-irrorata 15:174 1H-NMR of 15:125 Pseurata C 15:116 13C-NMR of 15:130 from Rabdosia pseudo-irrorata 15:174 ~H-NMR of 15:123 Pseurata D 15:118 13C-NMR of 15:132 from Rabdosia pseudo-irrorata 15:174 IH-NMR of 15:125 Pseurata E 15:120 t3C-NMR of 15:134 from Rabdosia pseudo-irrorata 15:174 ~H-NMR of 15:127 Pseurata F 15:118 13C-NMR of 15:132
670
from Rabdosia pseudo-irrorata 15:174 1H-NMR of 15:125 Psiadia 7:411 Psiadia trinervia 7:411-413;23:342 Psidium guajava 21:581;22:530;29:579 Psidium guianense 21:614 Psidium guyava L. 22:530 for epilepsy and convulsions in children 22:530 PSII inhibitors 26:368,371 Psilocine 21:68 Psilocybe mexicana 25:531 Psilocybine 21:68 Psilostachyins 7:215,237 Psi-tectorigenin 15:452,453,456 Psittacula krameri 5:837 hemoglobin components of 5:837 PSK derivatives 25:378 PSK in mitosis 25:377 PSK-receptor 25:378 PSK-a activity 25:378 Psolus fabricii 7:278,279;15:89;28:598 Psolus patagonicus 28:597 Psolus tabricci 25:701 Psolusoside A 7:278,279 from Psolusfabricii 7:278 Psolusoside B 7:278,279;15:89 Psoluthurin A 7:278,279 Psophocarpus tetragonolobus 29:605 Psoralea corylifolia L. 29:705 Psoralea glandulosa 22:354 Psoralen 9:402;18:978,20:499 170-NMR of 9:111,112 Psoriasis 9:514,517;30:484 use of l(x,25(OH)2D3 30:484 Psoroptes 28:416 Psoroptes cuniculi 21:612;28:415 Psoroptes mites 28:410 in bull fattening management 28:410 spread of 28:410 Psorospermin 13:368 from Psorospermum febrifugum 13:368 (+)-Psorospermin 4:371,372 synthesis of 4:371,372
Psorospermum febrifugum 7:417-420, 424 psoprspermin from 13:368 Psorosporum 22:580 Psudobaptigenin 27:498 Psychiatric disorders 30:369 anorexia 30:369 bipolar disorder 30:369 bulimia 30:369 effect of circadian activity on 30:369 obsessive compulsive disorder 30:369 panic disorder 30:369 schizophrenia 30:369 seasonal effective disorder 30:369 unipolar depression 30:369 Psychloleine 21:72 Psychodelic drugs 26:820 cocaine as 26:820 morphine as 26:820 semisynthetic LSD as 26:820 Psycholeine 22:26 Psychological effects 21:580 Psychomotor retardation 26:1130 as syndrome type-lA 26:1130 Psychoses 21:101 Psychotonin M 22:691,695 Psychotria campoutans 26:804 Psychotria curviflora 22:530 for convulsions 22:530 Psychotropic activity 7:7 Psychovegetative disorders 22:643,684 Psycotria colorata 30:205 to relieve abdominal pain 30:205 use in earache 30:205 Psycotria sp. 30:205 trimmer hodgkinsine from 30:205 Psyllium 13:660 Ptaquiloside 26:703,705,706,707,709712,714,716,719,722-725,727 three dimensional view of 26:710 Ptaquiloside Z 26:719,720 Ptaquilosin 26:723 Pteidanoside's 26:703,722 toxicity of 26:703,722
671 Pteridanoside 26:722 Pteridioside 26:704 Pteridium aquilinum 6:194 Pteridium aquilinum var. caudatum 26:687,690-692,695,696,698,699, 702,703,720,722,724,725,727 Pteridium arachnoideum 26:699 Pteridium esculentum 26:699 Pteridium laliusculum 26:690,702 Pteridium sp. 26:685-692,694-702, 704,720,721,723,724,726 Pteridophyllum genera 27:163 Pteridophyta 27:735 Pteris aquilina 26:691 Pteris cretica 26:745 Pterocarpanes 26:745 Pterocarpans 4:377,378,383,385,386; 20:730,774,775 ;22:76 synthesis of 16:564-565 Pterocarpenoids 27:894 Pterocarpus santalinus 20:774 Pterocarya paliurus Batal 21:674;27:16 pterocaryoside A from 27:16 pterocaryoside B from 27:16 secodammarane from 21:674 Pterocaryoside A 27:16,31,32 structure of 27:32 Pterocaryoside B 27:16,31,32 structure of 27:32 Pterocaulon plystachium 22:347 rhamnetin from 22:347 Pterogorgia citrina 17:99 Pterogyne nitenes 20:489 guanidine alkaloids from 20:488 Pterogynidine 20:488 Pterogynine 20:489 (+)-Pteropodine 13:490,491 Pterosin A&B 26:702 Pterosin F 26:700,701,702 Pterositlbene 22:627 Pterosterone 26:700 papuline 26:585 papulinone 26:585 t-zeatin 26:585 t-zeatin riboside 26:585 Pterostilbene 20:730,20:774 Pterygote 22:376 Ptilocaulin 6:4 synthesis of 6:4
Ptilocaulis spiculifer 28:690 alkyl sulfate from 28:690 dakaramine from 28:690 Ptilometra sp. 28:719 anthraquinones from 28:719 Ptilosarcus gurney 21:252 ptilosarcone from 21:252 Ptilostemonal 8:39,40 Ptilostemonol 8:46,47 synthesis of 8:46,47 Ptilostemonol acetate 8:40,41 synthesis of 8:47 Ptilota filicina 25:718 P-Toluene sulfonic acid 22:203 PTX 251 D alkaloid 27:250 PTX 341A 27:247-249 structure of 27:249 PTX B alkaloid 27:249,250 PTX-A alkaloids 27:247-249 Ptychodiscus brevis 6:135 Ptygonum bistorta 22:118 Puberulin A 26:243,244 as PAF-induced inhibitor 26:244 Puberulin A&C 26:243,244 Puberulin C 26:243,244 as PAF-induced inhibitor 26:244 Pubescenin 20:191 from Physalis pubescens 20:191 Pubescenol 20:180,20:181,20:194 Puccinia 9:203,220,222 Puccinia antirrhini 9:220 Puccinia arachidis 9:220 Puccinia coronata 9:220,226 Puccinia coronata f sp. avenae 9:220223,228 Puccinia coronata f sp.jestucae 9:221 Puccinia graminis 9:220,226 Puccinia graminis f sp. tritici 9:220, 221,228 Puccinia helianthi 9:220 Puccinia podophylli 26:176 Pueraria lobata 25:93 Pueraria thomsonii 25:93 Puerariae Flos 25:91,94,99,100 Puerariae lobata 25:91,103 Puerarin 22:446 PUFA 25:933 PuGPu sequences 21:419 Pulchea indica 7:185
672 Pulcherricium caeruleum 29:284 Pulcherrimins A 20:475 Pulcherrimins D 20:475 Pulegone 1:579;25:125,156;27:375 ketone chiral auxiliaries from 1:579 preparation of 1:579 structure of 27:375 (S)-Pulegone 13:598;20:74 S-(-)-Pulegone 16:192 R-Pulegone 20:272 (+)-Pulegone 9:535;10:410;13:11,13; 16:192,225 ;18:319;21:585 ;26:86,88; 29:83;8:224 activity in AM assay system 29:83 Pullulan 5:288,289,307,314 Pullulanases 10:498 Pulmericin 16:299 antifungal activity of 16:299 antileukemic activity of 16:299 cytotoxic activity 16:299 Pulmiliotoxins 16:426 Pulmonary colonization 19:370 Pulmonary tumors 24:224,232,261 Pulmonary vascular injury 30:70 role of serine protease in 30:70 role of thrombin in 30:70 Pulmonata 17:3 Pulsatilla chinensis 29:652,653 Pulse experiment 9:598,599 Pumiliotoxin 12:294;19:53,463 enantioselective synthesis of 4:584,585;19:53 Pumiliotoxin A 1:287;11:244;19:52-59 synthesis of 1:287;19:52-59 synthesis of analogues 1:294 Pumiliotoxin A-C 9:321,323 Pumiliotoxin alkaloids 27:238,239 allo-PTX 323 B alkaloid 27:249,250 biological activity of 27:249,250 fragmentation pathway of 27:239 Pumiliotoxin B 12:294;19:54 absolute configuration of 12:294 activity of 12:294 diastereomer of 12:294 (15S, 16S)-erythro diastereomer
of 12:294 from Dendrobates pumilio 12:294 synthesis of 12:296;19:54 (+)-Pumiliotoxin C 16:459-460 synthesis of 16:459-460 (-)-Pumiliotoxin C 18:319 Pumiliotoxin C (decahydroquinolines) 11:244 (-)-Pumiliotoxin C 6,19:8-10,12-13 hydrochloride salt of 19:4 racemic synthesis of 19:4 total synthesis of 19:4 X-ray crystallographic analysis of 19:4 Pumiliotoxin N-oxides 12:323 from Dendrobates speciosus 12:294 Pumiliotoxins 21:73 Pumilitoxin 251D 19:52,19:486 synthesis of 12:296 Pummerer intermediate 3:461 ;14:646 Pummerer reaction 1:63-65;4:139,464; 10:678,682;11:326,327;14:539-546, 747;19:14 Pummerer rearrangement 4:36-39,496, 505,506,510;6:317-319,321,328,335; 12:160,161,324;14:539;16:230,671 Punaglandin 1:687 synthesis of 1:687 Punctatin 14:646,647 synthesis of 14:646,647 Punctularia atropupurescens 29:286 Pungency 17:379 Punglandis 5:377,385 Punica granatum L. 21:504;22:530; 29:582,584 for epilepsy 22:530 Punta Toro virus 30:411 treatment of 30:411 Pupukeanane skeleton 25:851 (+)-Pupukeanone 6:83,84 from Diels-Alder adduct 6:83,84 from 4,6-dimethyl- 1,3-cyclohexadiene 6:83,84 synthesis of 6:83,84 (+)-9-Pupukeanone 6:83,84 by Birch reduction 6:83,84 by intramolecular Diels-Alder
673
reaction 6:83,84 from p-cresyl methyl ether 6:83,84 Schiehser-White synthesis of 6:83,84 Purealidins 25:757 Purealidins J, K and Q 25:766,767 Purealidins N,P and Q 25:766,767 Purification 4:282,283 of oligonucleotides 4:282,283 Purification methods 30:825 affinity chromatography as 30:825 gel filtration as 30:825 high-pressure liquid chromatography (HPLC) as 30:825 ion exchange as 30:825 sulfuric ammonia precipitation as 30:825 Purifying blood 26:50 Herniaria hirsuta in 26:50 Purine alkaloids 21:72 Purine receptors 25:532 Purines 220 9:73 Puromycin reaction 7:386 Purpurea glycoside A 15:362 Purpurea glycoside B 15:362 Purpurin 25:543,544;26:640,649,657, 663,666,674 Purpurogallin 25:546;29:589 effects on PEP 29:589 Purpurone 23:252 Purpurosamine 13 4:120-127 synthetic approaches to 4:120-127 6-epi-Purpurosamine B 4:120-127 synthetic approaches to 4:120-127 6-epi-Purpurosamine B derivative 4:125 synthesis of 4:125 Purpurosamine C 4:115; 125 by [4+2] cycloaddition 4:115 from levoglucosenone 14:268 synthesis of 4:115-118 total synthesis 4:123 synthesis of 14:268 Purpuroxanthin 26:657,666 Pusescenol 20:242 Pustulan 5:311,322
Putative receptor proteins 25:398 Putative satiety factor 24:910 effect of cholecystokinin 24:910 Putranjivadione 30:644 stereochemistry of 30:645 NOESu experiment of 30:645 Putrescine 22:724;25:66;26:1259, 1260,1263,1276,1277 Putterlickia verrucosa 23:70 Puupehenone 15:299;25:698,699 from Heteronema species 6:23 from Hyrtios eubanuma 6:23 synthesis of 6:23,24 Puwainaphycin C 25:793,794 Pycnamine 26:824,826 Pycnanthus angolensis 26:219,473 Pycnogonids 17:105 Pycnonotus cafer 5:837 hemoglobin components of 5:837 Pycnonotusjocosus 5:837 hemoglobin components of 5:837 Pycnopodia heliantoides 15:46 pycnopodiosides A,B and C from 15:61 Pycnopodiosides A, B and C 15:61 from Pycnopodia heliantoides 15:61 Pycnoporus 26:1013 Pycnoporus cinnabarinus 26:1010-1016 Pycnoporus coccineus 26:1012 Pycnoporus sanguineus 26:1012 Pygmol 7:218 from Artemisia pygmaea 7:218 Pyochelin 21:186 Pyocheline 9:539,540 Pyoluteoin 21:186;23:349 Pyoverdins (pseudobactin) 9:538,539, 541-547,549-555 biogenesis of 9:552,553 Pyrano [2,3-b] pyridin-2-one 13:545 Pyrano [2,3-c] acridin-7-one-(acronycine) derivatives 13:348 Pyrano [3,2-b] acridin-6-one(isoacronycine) derivatives 13:348 Pyranoacridone 13:347,358,370,-374 Pyranoannulated diquinane derivatives 10:426-428
674
Pyranocoumarin 20:497,499;27:429 biological activity of 27:429 decursin 25:543 decursin angelate 25:543 Pyranocoumarin decursin 27:835 Pyranofoline 13:348,349,370,372 Pyranoid carbasugars 29:466 acarbose as 29:467 as analogues of UDP-galactose 29:472 as cellular messengers 29:467 as insulin release mediators 29:467 as naturally occurring aldohexoses 29:466 as protein anchors 29:467 as sweeteners 29:467 biological activities of 29:466 carbaaldopyranoses as 29:467 effects on glycosidase enzyme 29:467 effects on glycosyltransferase enzyme 29:467 gabosines as 29:467 galactosyltransferase inhibition by 29:472 validamine as 29:467 Pyranoid carbasugars synthesis 29:466 by Duhram 29:466 by Furuta 29:466 by McCasland 29:466 Pyranoid glycal 10:342 palladium-mediated reactions of 10:342 stereoselective arylation of 10:345 Pyranoid linalool oxide 25:143 cis and trans 25:143 Pyranonaphthoquinones 4:591 Pyranose 17:638 derivative of 17:638 semi-synthesis of 17:638-640 Pyranosic homologation 21:431,432 Pyranoside 10:373 enol esters from 10:373 stereoselective C-glycosylations 10:373 4-O-Pyranosyl sugars 15:436 6-O-Pyranosyl sugars 15:436
Pyranoxanthones 7:411 Pyrazinamide 2:424 Pyrazines 13:318-321 synthesis of 5:254-258 Pyrazofurin 10:355 synthesis of 10:355 Pyrazofurin A 10:392 by Wittig reaction 10:392 from ribofuranose 10:392 Pyrazofurin B 10:392 by Wittig reaction 10:392 from ribofuranose 10:392 Pyrazolopyridines 1:167 Pyrenomycetes 23:109 Pyrenophora avenae 19:154 (-)-Pyrenophorin 19:154-155 antifungal antiobiotic 19:154-155 produced by 19:154 synthesis of 19:154 Pyrenophorin 4:518-520 synthesis of 4:518-520 Pyrethrin 27:581 Pyrethrin analogues 14:397-405 insecticidal activity of 14:398 synthesis of 14:397-405 Pyrethrin I 27:589 Pyrethrin II 27:589 Pyrethroidinin 27:582 Pyrethrosin 27:566 Pyricularia oryzae 1:404;4:598;12:401; 15:385;22:398,273;28:114 Pyricularia sp. 16:302 Pyridine monoterpene alkaloids 6:527-530 Pyridine nucleotides 20:868 Pyridine substrates 18:369 Pyridine-2,5-dicarboxylic acid 12:283 bicyclic keto-acid from 12:283 Pyridine-2-carboxamide-netropsin 5:570 Pyridinebetaine B 25:873 Pyridinium acetate 11:84,85 lactonization with 11:84,85 Pyridinium acetate 11:84,85 lactonization with 11:84,85 Pyridinium chlorochromate 7:478; 11:93,94;12:492;21:739
675
oxidation with 4:117,118;6:116, 118 Pyridinium dichromate 11:350 Pyridinium methylides 1:334,335 cycloaddition with 1:334,335 Pyridinium salts 1:91 reduction with dithionite 1:91 Pyridinone 13:545 Pyridne carboxaldehyde 6:3122from 2-bromopyridine 6:312 Pyrido [4,3,2,-m,n,]acridine skeleton 25:894 Pyrido [4,3,2,-m,n] thiazolo [32-b] acridinum skeleton 25:893 Pyrido [4,3b] carbazole alkaloids 6:513,514 in Loganiaceae from 6:507 11H-Pyrido-4,3,2-acridine moiety 21:269 Pyridoacridine 25:707,709 Pyridoacridine alkaloids 23:268 Pyridoacridine alkaloids 28:639 cytotoxic effects on KB cells 28:639 Pyridoacridines 21:269 Pyridone 10:618,619 photopyridone from 10:618,619 Pyridone-oxazole B 90063 25:841 Pyridones 18:315-386 selective synthesis of 18:315-386 Pyridoxal phosphate 10:148 Pyridoxine 2:424 2-(2-Pyridyl) ethyl 4:286 as protecting group 4:286 2-Pyridylcarbinol 12:283 hydrogenation of 12:283 Pyrilium oxide 1:189 isomerization of 1:189 Pyrilium salt 7:459 Pyrimethamine 20:526;26:805 Pyrimidine nucleoside 4:223,224 Pyrimidine phosphorylase 4:230 inhibition of 4:230 Pyrimidine phosphorylase 4:230 inhibition of 4:230 Pyrimidine-2-amino-2-deoxynucleosides 4:239 synthesis of 4:239
Pyrimidinone 26:220;22:292 Pyrocatechol 8:305 from phenol 8:295 from benzene 8:295 Pyrocurzerenone 23:827 Pyrogallic acid 26:359 Pyrogallol 20:273;22:319;25:613 Pyroglutamic acid 13:112 3-acylpyrrol-2(5 H)-ones from 13:112 3-methoxycarbonylpyrrol-2 (5 H)one from 13:112 (S)-Pyroglutamic acid 19:32 chiral pool 19:32 ofkuwanon G 17:455 L-Pyroglutamic acid 26:1242 Pyroglutamic acid 27:394 from red Ginseng root 27:394 structure of 27:394,395 Pyrrole-2-carboxylic acid 26:819 Pyroloiminoquinones 25:824 Pyrrolomycins 25:757 Pyrolysin 14:268;17:455;25:390 levoglucosenone from 14:268 ofisoquinoline N-oxide 6:468 of N-acyllactams 6:430,431 of N-lauryl-6-methyl-2piperidone 6:430,431 of acid-treated cellulose 14:268 ofprotopine N-oxide 6:494 of microgranular cellulose 14:268 Pyronaridine 25:344 T-Pyrone 5:591 ;22:312 c~-Pyrone 5:590;15:474 oc-Pyrone convolvupyrone 15:342 T-Pyrone ring 23:57 c~-Pyrones 23:339 T-Pyrones 23:339 Pyrones 22:76;24:541-544 as antiviral compound 24:541-544 Pyrrhocoris apterus 22:382,383,392 (3S,5R,6S,3'R)-Pyrrhoxanthin 30:517 structure of 30:517 Pyrrhoxanthinol 6:143,145 synthesis of 6:143,145 Pyrrocorphins 9:604,605
676
Pyrroglutamic acid 6:438-440 (2S,5 R )-cis- 5 -butyl-2-heptyl pyrrolidine from 6:438-440 Pyrrol [2,l-j] quinolines 25:859 Pyrrole 8:269;22:13 synthesis of 8:269 Pyrrole alkaloids 17:88 Pyrrole-amidine antibiotics 5:561 Pyrrole-imidazole alkaloid 28:690 taurodispacamide A 28:690 antihistaminic activity of 28:690 Pyrrolidine 5:3;21:378,385;22:204,739 (2R,5S)-cis-Pyrrolidine 6:438 from L-glutamic acid 6:438 synthesis of 6:438 (3R,5S)-trans-Pyrrolidine 6:439-440 from L-glutamic acid 6:439-440 synthesis of 6:439,440 Pyrrolidine (2R,3R) 12:281 Pyrrolidine alkaloids 12:472; 13:474-483 asymmetric synthesis of 6:442,443 synthesis of 6:442,443,445 Pyrrolidine derivatives 14:556,570 absolute configuration of 14:556,570 alkaline hydrolysis of 14:569, 570 from alkyne compound 14:570 from c~-allokanic acid 14:556, 557 from allyl alcohol 14:571 ~H-NMR spectra of 14:556 from (R)-l-phenyl ethyl amine 14:555 from (S)-1-phenyl ethyl amine 14:555 from propargyl alcohol 14:569, 570 from L-serine 14:568 from L-tartaric acid 14:568 pyrrolizidine alkaloids from 14:568-571 synthesis of 12:471-476; 14:553-559,568-571 via asymmetric intramolecular Michael reaction 14:553-559,568-571
via Sharpless asymmetric epoxidation 14:568-571 Wittig reaction of 14:556,557 (+)-Pyrrolidine oxime 19:84 Pyrrolidine ring construction 6:437-439 in pyrrolidine venom alkaloid synthesis 6:437-439 Pyrrolidine venom alkaloids 6:437-439 by pyrrolidine ring construction 6:437-439 distribution o f 6:436 in ants 6:434-444 relative configuration of 6:435 synthesis of 6:436,443,444 2,4-Pyrrolidinedione ring system 21:374 Pyrrolidines 10:524 glycosidase inhibitors of 10:524 [LPyrrolidino-L-rhodino-pyranoside 14:132 2-Pyrrolidones 14:560,561 absolute configuration of 14:560,561 a-allokainic acid from 14:560,561 from (R)-l-phenyl ethylamine 14:560,561 from (S)- 1-phenyl ethylamine 14:560,561 synthesis of 14:560,561 via asymmetric intramolecular Michael reaction 14:560,561 Wittig reaction of 14:560,561 Pyrroline alkaloids 6:436,443,444 synthesis of 6:436,443,444 [2+3]Pyrroline annulation 3:55 intermolecular 3:57 Pyrroline intermediate 6:447,448 syn-addition to 6:447,448 1-Pyrroline- 1-oxide 12:290 cycloaddition with pentene 12:290 3-(A~-Pyrroliniumyl) propanal 12:293 with benzyl-3-oxohexanoate 12:293 Pyrrolintrin 25:757 Pyrrolinyl-fl-carbolines G,H,J,P & Q 25:782
677 Pyrrolizidine 10:564;22:13 synthesis of 10:564 Pyrrolizidine alkaloids 14:568-571; 21:4,97 synthesis of 1:267-275,325,326 from pyrrolidines 14:568-571 total synthesis of 3:49-55 Pyrrolizidines Pyrrolnitrin 21:186 Pyrrolo [1,2-a] indoles 13:437 Pyrrolo [2, I-C][ 1,4]benzodiazepines (PBDs) 21:419 Pyrrolo[ 1,4]benzodiazepine (PBD) 21:419 Pyrrolo [2,1 -C] [ 1,4]benzodiazepines 21:419 Pyrrolo-2(5H)-ones 13:110,112,113, 117,118,120-130,133,136,139,140, 144,150 Pyrroloindole 1:178,180 Pyrrolomycin antibiotics 25:794 Pyrrolone 21:415,416 Pyrroloquinoline alkaloids 7:444; 21:311 Pyrroloquinoline quinone 9:581 Pyrroloquinolines 25:705,707 1-Pyrrolylacetic acid 19:18 Pyrrolyl-fl-carbolines A and M 25:782 Pyrromethene 9:592,593 Pyrromycin 4:317 e-Pyrromycinone 11:120 Pyrromycinone 4:330 synthesis of 4:330 Pyrroxanthin 23:178 Pyrus 29:588 Pyrus communis 23:750;26:592;29:588 Pyruvate 20:855-859 Pyruvate dependent aldolases 30:423 catabolic function of 30:423 equilibrium of 30:423 in vivo 30:423 Pyruvate kinase 11:208 Pyruvate orthophosphate dikinase 11:182 from Propionibacterium shermanii 11:182 Pyruvate-dependent aldolases 30:424 structure of 30:424 Pyruvic acid 23:463
Pythium 25:303 Pythium acanthicum 5:276 Pythium middletoni 21:199 Pythium sp. 5:276;21:197,221 Pythium ultimum 7:183,190;21:186, 187,211,219-221,223,229,238; 22:482 Pytophthora cinnamomi 5:276 Pytressin-induced coronary spasm 25:594 Pyura sacciformis 23:257
QSAR analysis 30:195 of A8-tetrahydrocannabinol 30:195 Quadrangularin A 26:567 Quadranguloside 25:206 Quadrature detection 9:97 (-)-Quadrone 16:127 (+)-Quadrone 4:674 Quadrupole mass spectrometers 9:487 Quantamycin 1:429,430 synthesis of 1:429,430 Quantitation 21:548 using UV absorbance 21:548 Quasi-dimeric-type alkaloid 5:111 ceridimine 5:111 Quasi-molecular ions 2:4,43,47 Quassi excelsia 7:124 Quassia amara 7:392 quassin from 7:392 Quassia indica 23:296 Quassia simarouba 28:400 Quassimarin 11:79,80,95-105 synthesis of 11:79,80,95-105 Quassin 7:124,392,396;11:71,105; 25:59,548;26:816,817 1513-acyloxyquassin from 11:79,80 from Quassia amara 7:392 synthesis of 11:73-76 (+)-Quassin 11:76,77 synthesis of 11:76,77 Quassinoid derivatives 23:303 preparation of 23:303 Quassinoid glycoside 23:296 Quassinoids 5:38-40;7:391-394; 24:282-284
678 L3C-NMR spectrum of 5:38-40 ~H-NMR spectrum of 5:39-41 antileukaemic activity of 7:382-387 antimalarial activity of 7:391-394 antitumor 11:71-111 APT spectrum of 5:39 CSCM 1D spectrum of 5:39 DEPT spectrum of 5:39 from Brucea antidysenterica 7:374-376 from Bruceajavanica 7:377-379 metabolism of 7:388 SFORD spectrum of 5:38 SINEPT spectrum of 5:39 synthesis of 11:71-111 toxicity of 7:388,389 Quaternary benzo [c]phenanthridine alkaloids chelerythrine 27:155,156, 161,162 chemistry of 27:155 fagaridine 27:156 formation of free bases in 27:155 in Fumariaceae family 27:155, 157,161 in Papaveraceae family 27:155, 157,161 isofagaridine 27:156 nitidine 27:156 punctatine 27:156 sanguinarine 27:155,156,161, 162 Quaternary carbon 8:3-14;14:631-644 asymmetric 10:405-412, 426-428 asymmetric induction of 10:412 chiral construction of 4:4-27; 14:631-644 synthesis of 8:3-14 through addition-elimination process 14:631-644 Quaternization 6:513,514 by 4-nitrobenzyl bromide 6:513, 514 Quebrachamine 14:632-636;19:143 synthesis of 14:632-636;19:143 Quebrachidine 5:127,9:183,13:405
Quebrachidine-type alkaloids 5:78 14-ethoxy- 15,18-oxidoquebrachidine (hyderabadine) 5:78 quebrachidine 5:78 tetraphyllicine 5:79 tetraphyllicine monomethoxybenzoate 5:79 tetraphyllicine trimethoxybenzoate 5:79 Quebrachitol 10:521,522 D-Quebrachitol 18:396 L-Quebrachitol 13:190,201,219;18:439 valiolamine from 13:199 Queen substance 4:554,555 synthesis of 4:554,555 Quercetagetin 7:227;25:541 3,5,6,7,3',4'-Quercetagetin (6-hydroxyquercetin hexahydroxyflavone) (flavonol) 29:573 effects on HIV-1 protease 29:573 Quercetin 5:652,7:206,227,15:460; 20:782;22:166,317,323,327,328,352, 423,425,427,429,431,433,434,436, 438,440,441,614,645,664,661,663, 665 ;23:537,551,742 ;23:773 ;26:314, 359,742,746-748,750,757,758,696, 697,714,1008;27:895,746;29:578; 30:208,749 analgesic effect of 30:208 effects on aminopeptidase N 29:578 effects on ACE 29:580 effects on HIV- 1 protease 29:573 effects on LELA 29:585 effects on NEP 29:581 effects on PEP 29:589 structure of 30:749 Quercetin 3-glucoside 23:342 Quercetin 3-O-a-L-rhamnopyranoside 28:64,65 anti-oxidant activity of 28:64,65 Quercetin 3-O-[3-D-galactopyranoside 28:64 anti-oxidant activity of 28:64 Quercetin 3-rutinoside 23:747
679
Quercetin 3-rutinoside 4'-diglucoside 23:747 Quercetin-3 [3-D-glucopyranoside-6"gallate 22:614 Quercetin-3,7-digalactoside 26:314 Quercetin-3-glucoside 26:314,763 Quercetin-3-methyl ether 20:712 from Salvia limbata 20:712 Quercetin-3-O- [3-D-glucopyranoside-2' gallate 22:165 Quercetin-3-O-(2"-O-galloyl)-glucoside 29:580 effects on ACE 29:580 Quercetin-3-O-dirhamnoside 22:615 Quercetin-3-O-rhamnopyranoside-2"gallate 22:615 Quercetin-3-O-rhanmoside 22:615 Quercetin-3-O-tx-L-rhamnopyranoside 28:64 anti-oxidant activity of 28:64 Quercetin-3-rutinoside 28:285 in foods 28:285 Quercetin-3 [3-D-glucopyranoside-2"gallate 22:614 Quercetin-4'-glucoside 28:285 in foods 28:285 Quercitrin 26:359;29:581 effects on ACE 29:581 Quercus aliena 23:417 Quercus faginea 27:663 Quercus genera 27:755 Quercus ilex ssp. ballota 27:663 Quercus imbricaria 21:657 Quercus infectoria 22:530 for epilepsy 22:530 Quercus pedunculata 29:589 Quercus phillyraeoides 23:403 Quercus sp. 21:502 Quercus tinctoria 29:581 Queretaroic acid 25:60 Questin 22:609,610 Questinol 22:609,610 Quidine 25:344 Quiesone 9:219,220 Quil A 21:646,650 Quillic acid [3-O-[3-D-galacttopyrano syl- ( 1---~2) [[3-D-
xylopyranosyl-(1--~3)]-[3-Dglucurono-pyranoside] 26:21 Quillaia 26:55 of adjuvant activity 26:55 Quillaic acid 7:155,156;21:646,670 Quillaja saponaria 21:646,648;24:131, 133,138,139,144,149,152,155-158, 167,171;26:54 Quinacrine 22:147;25:593 Quinaldic acid 20:118 by Streptomyces azurens 11:209, 210 from L-tryptophan 11:209,210 Quinalizarin 25:543,544 Quinate 23:740 Quinghaosu 7:238 Quinic acid 12:15;23:744 enoate triol from 12:15 derivatives of 17:144 (-)-Quinic acid 13:201,422 Quinic acid esters 25:919,947 Quinidine 21:73,96,97,102,108,109, 488;22:146,32,35 ;25:347 ;25:347 Quinimax 26:836 Quinine 21:73,96,97,102,108,109,488; 25:344,347,478,546;25:344,347,478, 546;26:97,780,781,800,835,838,888; 3:385,7:424,13:656 Quinizarin 25:544 Quinizarin-2-carboxylic acid 26:664 Quinizirine 4:350 attachment of sugars 4:350 Quinoaldimine 26:1272 Quinocarcin 10:117,126;19:290 absolute configuration of 10:126 antitumor activity of 10:117 chemical modification of 19:290 inhibitor of DNA 19:290 structure of 19:289 structure-activity relationship of 19:289 synthesis of 1:341,342; 10:120-141 (-)-Quinocarcin 19:289,311 absolute stereochemistry of 19:311 antimicrobial activity of 19:289 antitumor activity of 19:289 isolation of 19:289
680
retro-synthetic plan of 19:311 total synthesis of 19:311-316 Quinocarcinamide 19:304-305 retrosynthetic analysis of 19:304-305 structure of 19:289 Quinocarcinol 19:289,291 pharmacological activity of 19:290 (• 19:293-294 retrosynthetic analysis of 19:293-294 Quinocarcins 10:115-117 pharmacological activity of 10:115-117 transformation of 10:119-120 Quinocide 22:150 o-Quinodimethanes 4:582,583 generation of 4:582,583 Quinoketimine 26:1272 Quinolidizine macrocyclic alkaloids 21:285 Quinoline alkaloids 13:662;21:68,73,84 Quinoline antimalarial drugs 25:329, 348,349 Quinoline drug family 25:343,360 Quinoline drugs 25:348 Quinoline quinone methide 2:128 Quinoline-5-carboxylic acid 14:763 isokomarovine from 14:763 komarovidine from 14:763 Quinoline-8-carboxaldehyde 14:763 Quinoline-based antimalarials 25:344 Quinoline-ring antimalarial drugs 25:327 Quinolines 10:185;20:517,518;22:14; 23:268 ;25:327,345,347,348 ;25:327, 345,347,348 Quinolinic acid 26:965,966,968,970 Quinolizidine 21:56,73,107;24:578, 604,605 ;27:244,246 ~3C spectra of 24:604,605 structure of 27:244,246 Quinolizidine alkaloids 13:483-489, 732-742;21:51,73,91,98,110; 27:233,276,287 bioactivity of 27:233 biosynthesis of 14:738,739 from amphibans 27:234
from ants 27:234 structure of 27:233 synthesis of 1:365-367; 14:732-738 Quinolizidine alkaloid vasicinol 25:536 Quinolizidine alkaloid spartein (lupinidine) 25:534 bis-Quinolizidine alkaloids 21:267 Quinolizidine derivatives 27:284,285 testing against Mycobacterium tuberculosis 27:284 Quinolizidines 1:369;22:14 nitrogen inversion in 1:369 trans to cis epimerization 1:369 Quinolone alkaloids 2:121 dimeric 2:121 Quinone 5:429-441,754,821,822; 24:503-509,541-544 as antiviral compound 24:503509,541-544 o-Quinone 5:434 Quinone methide 5:464-466,487,492, 744,745,747 Quinone methides 30:694 antiplasmodial activity of 30:694 o-Quinone methides 4:582,583 1,4-Quinone unit 23:53 Quinone Diels-Alder adducts 16:548 o-Quinoneimine 26:976,986,988,992, 998,1000,1002 Quinoneimine 26:979 Quinonemethide 5-isopropylidene-3,8dimethyl- 1-azulenone 14:320 Quinonemethide compounds 2:408 Quinone-methide triterpenes 5:745 Quinonemethide triterpenoids 23:709 examples of 23:709 Quinonemethides 30:666 biosynthetic pathway of 30:666 Quinones 7:427;23:537,551 ;27:849; 30:304,682 biosynthesis of 30:682 from angiosperms 30:304 from bacteria 30:304 from fungi 30:304 from gymnosperms 30:304 from lichens 30:304 molluscicidal activity of 7:427 occurrence of 30:304
681
plant sources of 23:551 structural characteristics of 30:304 ortho-Quinones 27:849 Quinone-styrene reaction 16:547, 551-552,559,560,564,565 Lewis-acid promoted 16:565 Quinonization 26:1287 Quinonoid 7:408 Quinoproteins 9:581 ;26:1259,1270, 1273,1277,1278,1279,1283,1285, 1286,1290 Quinotin-heme complex 25:348 Quinovic acid 7:218,60 derivatives of 17:123 glycosides of 17:124-125 antiviral activity of 17:134 from Artemisia vulgaris 7:218 D-Quinovose 7:268,270,273,275,277, 278,190 Quinovose 7:270,272,275,286-289,292, 293,302 Quinuclidine derivative 1:112 Quisqualic acid 22:25;26:476 Quisqualis indica 26:476 Rabbit muscle aldolase (RAMA) 11:467 Rabbit pancreas 12:390 by staurosporine 12:390 study of protein kinase in 12:390 Rabbit veins 12:390 study of protein kinase in 12:390 Rabdocoetsin B 15:171 fromRabdosia coetsa 15:171 Rabdocoetsin D 15:138 13C-NMR of 15:155 from Rabdosia coetsa 15:171 IH-NMR of 15:146 Rabdoepigibberellolide 15:112 from Rabdosia shikokiana 15:112 Rabdoforrestin A 15:120 13C-NMR of 15:134 from Rabdosia forresti 15:171 ~H-NMR of 15:127 Rabdohakusin 15:162,63 13C-NMR of 15:165
from Rabdosia umbrosa var. hakusanensin 15:175 lH-NMR of 15:164 Rabdoinflexin A 15:140,149,157,172 13C-NMR of 15:157 from Rabdosia inflexa 15:172 lH-NMR of 15:149 Rabdoinflexin B 15:118 13C-NMR of 15:132 from Rabdosia inflexa 15:172 IH-NMR of 15:125 Rabdokaurin A 15:138 13C-NMR of 15:155 from Rabdosia longituba 15:173 IH-NMR of 15:146 Rabdokaurin B 15:143 13C-NMR of 15:161 from Rabdosia longituba 15:173 JH-NMR of 15:152 Rabdokumin A 15:118 ~3C-NMR of 15:132 from Rabdosia kunmingensis 15:172 IH-NMR of 15:125 Rabdokunmin B 15:116 13C-NMR of 15:130 from Rabdosia kunmingensis 15:172 ~H-NMR of 15:123 Rabdokunmin C 15:118 13C-NMR of 15:132 from Rabdosia kunmingensis 15:172 ~H-NMR of 15:125 Rabdokunmin D 15:118 13C-NMR of 15:132 from Rabdosia kunmingensis 15:172 IH-NMR of 15:125 Rabdokunmin E 15:120 13C-NMR of 15:134 from Rabdosia kunmingensis 15:172 IH-NMR of 15:127 Rabdolasional 15:143,153,162 13C-NMR of 15:161 from Rabdosia lasiocarpa 15:172 1H-NMR of 15:153
682
Rabdolatifolin 15:162,163 13C-NMR of 15:165 from Rabdosia umbrosa 15:175 from Rabdosia umbrosa var. latifolia 15:175 ~H-NMR of 15:164 Rabdolongin A 15:139 from Rabdosia langituba 15:173 IH-NMR of 15:148 Rabdolongin B 15:112 Rabdoloxin A 15:119 13C-NMR of 15:132 from Rabdosia loxothyrsa 15:173 1H-NMR of 15:126 Rabdoloxin B 15:119 13C-NMR of 15:133 from Rabdosia flexicaulis 15:171 from Rabdosia kunmingensis 15:172 from Rabdosia loxothyrsa 15:173 from Rabdosia parvifolia 15:173 ~H-NMR of 15:126 Rabdophyllin G (rabdosin C) 15:112, 144,162,176 from Rabdosia gaponica var. glaucocalyx 15:171 from Rabdosia henryi 15:172 from Rabdosiajaponica 15:172 from Rabdosia longituba 15:173 from R. macrophylla 15:173 lH-NMR of 15:153 Rabdophyllin H 15:140 13C-NMR of 15:157 from Rabdosia macrophylla 15:173 ~H-NMR of 15:148 Rabdoserrin A 15:140,149 t3C-NMR of 15:157 from Rabdosia inflexa 15:172 from Rabdosia serra 15:174 1H-NMR of 15:172 Rabdoserrin B 15:172 Rabdoserrin D 15:119,174 Rabdosia amethystoides 15:167 Rabdosia diterpenoids 15:112 classification of 15:112
Rabdosia eriocalyx 15:176 Rabdosia gerardiana 15:167 Rabdosia glutinosa 15:167 Rabdosiajaponica 15:111 Rabdosia laxiflora 15:176 Rabdosia lophanthoides 15:167 Rabdosia macrophylla 15:167 Rabdosia occidentalis 15:176 Rabdosia parvifolia 15:167 Rabdosia shikokiana 15:162,176 rabdoepigibberellolide from 15:112 Rabdosia sp. 15:111-185 diterpenoids from 15:111-185 Rabdosia strachey 15:167 Rabdosia trichocarpa 15:135,176 Rabdosichuanin A 15:142 ~3C-NMR of 15:159 from Rabdosia setschwanensis 15:174 IH-NMR of 15:151 Rabdosichuanin B 15:141 13C-NMR of 15:158 from Rabdosia setschwanensis 15:174 IH-NMR of 15:150 Rabdosichuanin C 15:142 13C-NMR of 15:159 from Rabdosia setschwanensis 15:174 ~H-NMR of 15:151 Rabdosichuanin D 15:140 13C-NMR of 15:157 from Rabdosia setschwanensis 15:174 1H-NMR of 15:148 Rabdoside 1 15:140 ~3C-NMR of 15:157 from Rabdosia eriocalyx 15:171 lH-NMR of 15:148 Rabdoside 2 15:140 13C-NMR of 15:157 from Rabdosia eriocalyx 15:171 1H-NMR of 15:149 Rabdosin 30:227 structure of 30:227 Rabdosin A 15:172 from Rabdosiajaponica 15:172 Rabdosin B 15:112,162
683
Rabdosin C 15:112 Rabdosinate 15:144 13C-NMR of 15:161 from Rabdosia gaponica var. glaucocalyx 15:171 from Rabdosia japonica 15:172 ~H-NMR of 15:153 Rabdosinatol (glaucocalyxin C) 15:112, 116 13C-NMR of 15:130 from Rabdosiajaponica 15:172 from Rabdosia japonica var. glaucocalyx 15:172 ~H-NMR of 15:123 Rabdoternin A 15:139 13C-NMR of 15:156 from Rabdosia ternifolia 15:175 IH-NMR of 15:147 Rabdoternin B 15:140 13C-NMR of 15:157 from Rabdosia ternifolia 15:175 1H-NMR of 15:148 Rabdoternin C 15:139 13C-NMR of 15:156 from Rabdosia ternifolia 15:175 IH-NMR of 15:147 Rabdoumbrosanin 15:162,163 ~3C-NMR of 15:165 from Rabdosia umbroba 15:175 IH-NMR of 15:164 Rabidaea platyphylla 22:513 for epilepsy 22:513 Rabies virus 30:409 inhibitor of 30:409 Rabies virus infection 30:409 in chicken embryo-related cells 30:409 Rabies virus replication 30:409 in nerve fibers 30:409 Rabyuennane A 15:119,133 from Rabdosia yuennanensis 15:175 IH-NMR of 15:126 Rabyuennane B 15:119 from Rabdosia yuennanensis 15:175 IH-NMR of 15:126 Rabyuennane C 15:120 ~3C-NMR of 15:134
from Rabdosia yuennanensis 15:175 1H-NMR of 15:127 Racemic acerolide 23:176 synthesis of 23:176 Racemic alcohol 11:348 by lithium aluminum hydride reduction of methyl ester 11:348 preparation of 11:348 Racemic compactin 13:562,563 synthesis of 13:562,563 Race-specific elicitor 25:397,398 Race-specific peptide elecitors 25:398, 399,400,401 Rachitic bone healing potencies 30:484 of vitamin D2 30:484 of vitamin D3 30:484 of vitamin D4 30:484 of vitamin D5 30:484 of vitamin D6 30:484 of vitamin D7 30:484 Raddeanamine 1:201,202 synthesis of 1:201,202 Raddeanidine 1:203,204 synthesis of 1:203,204 Raddeanone 1:203 synthesis of 1:203 Radermachera xylocarpa 29:722 Radical chemistry 16:30 Radical coupling reactions 11:464,465 Radical cyclization 1:256-258,292; 24:15-18 of haloolefins 3:13 of phenylselenyl derivative 3:462 of tertiary alcohol 16:235 stereoselective 19:54 thermal 16:41 tin mediated 1:483,490 with R3 SnH 3:38 Radical induced deoxygenations 14:157-162 of carbohydrates 14:157-162 Radical mechanism 14:166 Radical Michael addition 12:281 Radical olefin cyclization 3:327 Radical oxidation 27:346 Radical polymerization 6:541,542
684 Radical reduction 11:141 2-deoxy- 1-hydroxysugars from 11:141 of dithiocarbonates 3:475 Radical scavenging activity 23:362 of coumarin 23:335,356,357, 353,368,376,393,550,553 Radical spirocyclization 16:28,33,35, 41,51,53,63 thermal 16:55 Radical-alkene cyclization 3:327,328 Radical-cation coupling 24:776,777 Radicicol (monorden) 26:452 Radicinin 9:417,418 Radioimmunoassay 2:368,92,114,115; 15:361,500;19:628 of (+)-carvone 7:114,115 of(-)-carvone 7:114,115 Radioligands 30:814 from brain membrane synaptosomes 30:814 Radioprotecitve effect 23:134 Radioprotective activity 23:107 of [3-glucans 23:107 Radopholus similis 25:662;26:474 Radula complanata 2:283 Radula kojana 2:283 Radula perrottetii 2:283 Raeedeanine 1:203,205,206 synthesis of 1:203,205,206 Rahydroshikoccin 15:167 Rainbow trout eggs 11:429 polysialoglycoprotein of 11:429 Ralstonia solanacearum 26:933 RAMA (rabbit muscle aldolase) 11:467 RAMA-catalyzed reaction 14:176 Ramalina usnea 5:310,313 Raman spectrometry 26:1267 Raman spectroscopy 30:540 principles of 30:540 scope of 30:540 limitations of 30:540 Ramberg-Backlund olefination 18:205, 206 Ramberg-Backlund reaction 8:208 Ramberg-Backlund rearrangement 24:12,13 Ramulosin 16:3 from Pestalotia ramulosa 16:3
Randall-Selitto test 21:673 Randia dumetorum 21:660 Randia esculenta 22:530 for convulsions 22:530 Randia siamensis 21:673 Random Bi-Bi process 11:201 Random screening 24:415-418 of chemical selection 24:415,416 of combinatorial libraries 24:417 of compound libraries 24:415418 Random screening 24:415-418 of chemical selection 24:415,416 of combinatorial libraries 24:417 of compound libraries 24:415-418 Raney nickel 6:150,151 desulfurization 11:357 catalytic hydrogenation with 6:425 Ranitidine 25:612,617 Rankinidine 9:196,472 rANP-triggered signal transduction 25:382 Ranunculaceae 25:180;27:161,164,754 Rapamycin 22:257;25:892 Rapanea laetevirens 9:321 Rapanea melanophloeos 21:660,662 Rapanea umbellate 30:657 24-(E)-3-oxo-dammara-20,24dien-26-al from 30:657 Rapanone 7:183 Raphael 29:382 steganes synthesis by 29:382 Raphanation 4:227 Raphanus sativus L. 18:507;19:247; 23:342;26:1075 homoteasterone from 18:507 (3R*, 6S*)-Raphanusanins 26:1084 3R*, 6R*Raphanusanins 26:1084 Raphe nuclei 30:368 role in cognitive functions 30:368 Raphidophyceae I,II 6:134 Raphisia pallida 25:705 Rapoport 29:374 allocolchicinoids total synthesis by 29:374
685 Ras famesyltransferase inhibitors 21:404 Ras function inhibitors 15:450,451 compactin 15:450,451 oxanosine 15:449 Ras oncogene 22:621 ;24:403 Ras protein 24:403-464 famesylation of the carboxy terminal cystein residue of 24:403-464 post-translation modification of 24:403-404 Raspaciona aculeata 25:700 Rassu 29:453,483,489 carbafuranose synthesis by 29:453 dibromide synthesis by 29:483 thiocarbapyranoses synthesis by 29:488 Rat brain protein kinase C 12:389 Rat brain synaptosomes 30:807 ~t-affinity in 30:807 Rat mammary carcinogenesis model 30:592 cancer chemopreventive activity in 30:591 Rat serum vitamin D-binding protein (DBP) 30:494 binding assay for 30:494 Ratibida columnifera 19:771 Rattle box 1:514 Raubasine (ajmalicine) 25:30,31 Raucubaine 9:183,184 Raucubainine 9:183 Rauflorine 9:183 Raumacline 13:390,391 Rauniticine 9:171 Rauscher leukemia virus 21:430 Rauwolfia alkaloids 14:553;19:748 Rauwolfia heterophylla 1:125 Rauwolfia nitida 1:125,126 Rauwolfia sellowii 1:125 Rauwolfia serpentina 1:125,126,283, 390;2:369; 13:629,660;19: 748; 22:531; 26:1060;29:362 deserpidine from 8:283 for epilepsy 22:531 reserpine from 8:283 Rauwolfia suaveolens 13:390,411
Rauwolfia tetraphylla 1:126 Rauwolfia verticillata 13:391 Rauwolfia vomitoria L. 1:125,427;
22:531 for epilepsy 22:531 Rauwolscine 8:395,400,429;21:57; 22:19,22 Ravensara aromatica 27:377 Ravidomycin 10:343 C-glycoside analogues of 10:374 Reaction mechanism 14:561,562 of asymmetric intramolecular Michael reaction 14:561,562 Reactivity 27:740 of enzyme intermediates 27:740 Read and Vining 29:295 biosynthesis by 29:295 Rearranged abietane diterpenes 20:680-688 Rearranged diterpenoids 23:629 iaC-NMR data of 23:630 ~H-NMR data of 23:630 Rearranged lanostanes 5:750 Rearranged quinone-methide 5:744,745 [3,3]-Rearrangement 10:236 1,2-Rearrangement 10:412 of~,y-epoxy alcohols 10:412 Rearrangement 3:342,355-387,467,480; 10:233-236;24:204,292-293 of homohrringtonine skeleton 24:292 in C-glucoside synthesis 3:225-228 intramolecular 3:226-228 of substituted hydronaphthalene 14:355-387 of [4.3.1 ]-bicyclodecanes 14:355 anionic 3:467 of sulfonyl group 6:342 of 1-benzyl tetrahydroisoquinoline system 6:480 reductive 3:227 Rearrangement of camphor 4:626,627 2,6-hydride shifts in 4:626,627 2,3-exo-methyl shifts in 4:626, 627,633,634 1,2-Rearrangement reaction 10:592, 593
686
from pyranosides 10:592,593 pinacol type 10:592,593 Rebaudioside 27:8,9,13,22;314 in Sprague-Dawley 27:314 Rebaudioside A 15:16;27:5;29:101 activity in TPA bioassay system 29:101 Rebaudioside B 15:17;27:13,23,300 structure of 27:23 Rebaudioside C 15:16;27:13,22,23,300; 29:101 activity in TPA bioassay system 29:101 structure of 27:23 Rebaudioside D 27:13,23,300 structure of 27:23 Rebaudioside E 27:13,23,300 structure of 27:23 Rebeccamycin 5:55,56 aglycone of 1:15,19 antitumor activity 1:394 biosynthesis of 12:374 from Saccharothrix aerocolonigenes 12:366,368,374 synthesis of 1:21 synthesis of aglycone 1:15,19 Rec-assay 28:225 of 6-prenyleriodictyol 28:225 of 8-prenyleriodictyol 28:225 ofgancaonin C 28:225 of isoliquiritigenin 28:225 of licoisoflavanone 28:225 oflicoisoflavone B 28:225 ofsemilicoisoflavone B 28:225 Receptivity 9:110 oflTo 9:110 of 33S 9:110 of 77Se 9:110 of 125Te 9:110 131-133Receptor 21:18 a-Receptor 21:58 [3-Receptor 21:58 6-Receptor 22:296 g-Receptor 22:296 e~2Receptor 8:395-397,399 8-Receptor affinity 30:814 binding properties of 30:814
g-Receptor affinity 30:814 binding properties of 30:814 of glycopeptide 30:814 8-Receptor agonists 30:797 pharmacological activity of 30:797 p-Receptor agonists 30:797 pharmacological activity of 30:797 ~c-Receptor agonists 30:797,806 pharmacological activity of 30:797 p-Receptor antagonists 30:797 pharmacological activity of 30:797 8-Receptor antagonists 30:797 pharmacological activity of 30:797 ~c-Receptor antagonists 30:797 pharmacological activity of 30:797 Receptor binding 27:377 Receptor binding assay 30:810 in vitro 30:810 mouse vas deferens (MVD) activity in 30:810 of guinea-pig ileum (GPI) 30:810 Receptor binding properties 30:815 of Tyr-D-Ala-Phe- [~-DGlc(OAc)4]Tyr-Pro-Ser-NH2 30:815 of Tyr-D-Ala-Phe-Asp-Val-ValGly-NH2 (deltorphin C) 30:815 of Tyr-D-Ala-Phe-Asp-Val-ValThr([3-d-Glc)-Gly-NH2Tyr-DAla-Phe-Thr[~-D-Glc(OAc)4]Val-Val-Gly-NH2 30:815 of Tyr-D-Ala-Phe-Asp-Val-ValThr[[~-d-Glc( OA c )4]-G ly-NH2 : 30:815 of Tyr-D-Ala-Phe-Gly-Tyr-ProSer-NH2 (deltorphin C) 30:815 of Tyr-D-Ala-Phe-Gly-Tyr-ProThr([3-D-Glc)-Gly-NH2 30:815 of Tyr-D-Ala-Phe-Gly-Tyr-ProThr[[3-D-Glc(OAc)4]-Gly-NH2. 30:815
687
of Tyr-D-Ala-Phe-Thr(13-D-Glc)Tyr-Pro-Ser-NH2 30:815 of Tyr-D-Ala-Phe-Thr([3-D-Glc)Val-Val-Gly-NH2 30:815 Receptor tyrosine kinase (RTK) 25:512, 522,548 Receptor-like protein tyrosine phosphatases 27:874 132/Otz_Receptors 21:18 oc3[32-Receptors 27:282 ~4132-Receptors 27:282 Receptors 27:363;30:421 and cell-cell adhesion 30:421 and cell-cell communication 30:421 antigenic determinants of 30:421 for bacteria 30:421 ofchiral proteins 27:363 with enzymatic activity 27:824 without enzymatic activity 27:825 Recifeiolide 4:573 synthesis of 4:573 total synthesis of 8:176 Recinoleic acid 13:308-310,312,313, 315 Recombinant DNA 7:122 Recombinant DNA methods 2:352-360 Recombinant DNA techniques 7:29,609 Recombinant DNA technology 2:322 Recombinant prourokinase (pro-UK) 30:839 as fibrinolytic enzymes 30:839 Recombinant tissue-type plasminogen activator 30:839 as fibrinolytic enzymes 30:839 Recombination energy 2:3 of NO + 2:3 Red algae 23:342 Red rhizomes 23:820 Red sea tunicate 23:240 Red wine 27:430 biological activity of 27:430 Red wine 28:274 (+)-catechin in 28:274 (-)-epicatechin in 28:274 Red-A1 19:482 reduction with 6:289,290
Red-A1 19:482 reduction with 6:289,290 Red-colored cyanidin 21:515 Redox enzymes 24:983-987,1003 enzymatic activity 24:983-987, 1003 Redox inhibitors 30:225 of 5-1ipoxygenase 30:225 Redox-based assays 21:511 Red-Pigment Concentration Hormone (RPCH) 19:656 4'-Reduced- abscisic acid 27:334 Reduced nicotinamide adenine dinucleotide (NADH) 30:384 Reducing agents 19:120 3oc-Reductase 19:636 3[3-Reductase 19:636 Reductase inhibitory activity 21:590 Reduction 1:10,28-30,33,131,155-159, 165,166,315,316,386,592-595, 698-701 ;3:253,237,339-345,358, 590,660,718;6:115,116,119,124,126, 129,229,285,286,288,289,292,295, 296,298,299,428,426,509,511-515; 8:6,7,19,23,34,81-84,87,91-93, 98-100,103-106,162,163,165,181, 322,323,388,288;11:364-366; 12:19,45,151,152,281,283,287,290, 297,300,301,411,414;13:54,58,72, 499-502;16:155,294,295,301,307, 348;17:495;24:8,13,16,17,20,30-32, 60-63,65,66,68,72,73,85,94,103, 110,111,124,175,182,188,190,206, 207;27:830 2-amino alcohol by 12:411,414 acetal/ketal cleavage by 1:591-595 asymmetric 4:339-345 Baker's yeast 19:129 by Ueno method 10:322,323 catalytic 19:475 chelation controlled 3:253 chemoselective 16:307;19:299, 329 diastereoselective 1:591-595; 14:499-502;19:334 during FAB mass spectra 2:28-30,33,35 enantioselective 13:54
688
enzymatic 13:58
H-H-C-Relayed 13C-1H correlation spectrum 2:101 intramolecular 12:283;16:420 1-selectride 11:365,366 of (+)-2-oxoindolizine 12:284 of (-)-camphorquinone 4:660 of 17-oxoellipticine 6:509,511 of 1-piperideines 6:426 of 2-enals 20:831-839 of 2-enoates 20:824 of 2-methylseleno-2-phenyl-6heptene 8:7 of 2-oxocarboxylates 20:840-842 of 3-ketotrichothecene 6:229 of 7-oxoindolizidine 12:286,287 of 8-azido- 1-p-menthene 11:288 of allyl alcohol 20:831-839 of allylic alcohol 16:348 of amide 19:145 of azide 16:19 of carbonyl group 19:226,229 of C-C double bond 20:824 of conjugated double bond 16:155 of C-Se bond 8:7 of cuparenones 8:6 of cyclic [3-keto esters 1:697-701 of cyclopropane carbonitrile 12:287 of diterpenes 27:830 ofenamines 1:386 of exocyclic double bond 19:53 of exo-methylene-'/-lactone carbonyl 1:315,316 of farnesal 8:19 of fumarates 20:831-839 of halide 11:364 of imines 6:426,428 of indolizomycin 12:301 of isoxazolidine 12:290 ofketo group 16:348 ofketo lactone 16:301 of ketones 1:131 of kingiside-aglycone-O-silyl ether 16:307 of lactone to lactol 1:315,316
of N-[3-oxy-17-oxoellipticine 6:511 of primary mesylate 16:19 ofsubstrate 17:495 of symmetrical diketones 19:129 ofa,[3-acetylenic ketones 13:72 of a-amino ketones 12:411,414 of a-halo ketones 19:193 regioselective 6:288,289;16:135 selective 19:119,228 stereoselective 11:91 ;12:151, 152;19:259,473-474, 476 stereospecific 11:98 threo-selective of 12:300 under Luche conditions 12:297;19:357 using TIC13 (DME) 8:19 using titanium trichloride 11:364 with (S)-Alpine-hydride 19:158 with Baker's yeast 12:281 with BH3-Me2 S 12:281 with Bu2A1H 8:163 with Bu3SnC1-NaBH4 1:512 with DIBAH 6:426 with DIBAL 6:285,286;8:165; 16:295 with diisobutyl aluminium hydride 1:315,326;4:589,590; 6:115,116;11:105,106 with Et3SiH/BF3 10:388 with hydrazine 1:131 with K-selectride 12:151,152 with LAH 19:475 with LiA1H4 8:23,162,163,181 with lithium aluminum hydride 11:364 with lithium triethylborohydride 11:83,84 with L-Selectride 6:298,299; 19:147 with NaBH3CN 8:162 with NaBH4 16:348 with NaBH4/MoO3 4:237 with NaBH4/NiC12 4:237 with NaCNBH3 1:386 with NiC13-NaBH4 3:165,253 with Ph3P 12:281 with Raney Ni 16:294
689
with REDAL 6:288,289 with Selectride 8:181 with sodium borohydride 19:296 with sodium cyanoborohydride 11:87 with sodium dithionite 16:45 with sodium hydrotelluride 11:81,82,92,93 with TIC14 1:591-595 with trialkyl aluminium 6:426 with tributyl tin hydride 4:718 with tri-N-butyltin hydride 8:34 with yeast 1:697-701 with zinc/copper couple 11:364 Reductive acetylation 4:232,324 Reductive alkylation 10:409 of c~(phenylthio) methyl enone 10:409 Reductive amination 1:253,289,290, 301 ;11:302,350,429,437,438,445, 446,450 with acetone/cyanoborohydride 11:301,302 of 1,4-diketones 6:437,438 of ketones 6:429 of triketones 6:445,446 of 2,6,9-undecatrione 6:450 Reductive aminocyclization 6:433,434 of alkane-2,6-diones 6:433,434 Reductive cleavage 1:439 with LAH 1:439 Reductive cyclization 1:106,279,281 indolizidine from 11:241,242 of ketones 11:241,242 Reductive decyanation 6:431,432 of 2,6-dialy-2-cyanopiperidines 6:431,432 Reductive desulfurization 12:81,167, 307-309,319;14:185 Reductive elimination 19:6 of acyloxysulfones 4:522 ofallylic radicals 4:525 with low valent titanium 4:521-535 with zinc copper couple 4:119 Reductive hydrolysis 19:155 Reductive methylation 4:55;6:553,554
Reductive N-methylation 6:435,443 in ant alkaloids synthesis 6:435,443 Reductive opening 1:519 with Et3A1C1-CH2C12/Et3SiH 1:519 Reductive oxygenation 10:532 with NaBH4-DMF-O2 10:532 Reductive ozonolysis 4:523 Reductive rearrangement 3:253 of 3,4,6-tri-O-acetyl-D-glucal 3:253 Reductive transposition 6:11 in (+)-pachydictyol-A synthesis 6:11 Reduetline 21:405,406,407 Reflectance fluorometry 9:453 Reflexin 4:712 Reformatsky reaction 1:41,312,313, 520;8:232;14:478,727;20:569 of ethyl bromodifluoroacetate 16:727 of chiral 2-bromopropionic acid derivative 12:166 [3-selectivity of 12:167 vinylogous 3:38,39 with 4-acetoxy [3-1actam 12:166 Refractive index detection 9:462 Refractory breast cancer treatment 24:933 taxol for 24:933 Regelone 30:643 structure of 30:643 Regeol A 30:675 ~3C-NMR data of 30:675 IH-NMR of 30:675 MS spectrum of 30:675 UV absorption of 30:675 Regeol C 30:675 ~3C-NMR data of 30:675 ~H-NMR data of 30:675 NMR spectra of 30:675 Reginin D 23:405,412 Regioisomers 22:222 (-)-Regiolone 21:209 Regio-pyranocoumarins 18:993 Regioselective 11:315,316 ketalization 11:315,316
690
oxymercuration 11:324 ring expansion 11:280,281 Regioselective acylation 12:346,404 Regioselective alkylation 6:546,547 Regioselective aza-annulation 18:319, 327 Regioselective dehydration 13:561 Regioselective Diels-Alder reaction 14:48 Regioselective glycosidation 6:262 Regioselective hydroboration 13:130 Regioselective Michael addition 18:319 Regioselective nucleophilic substitution 18:406 Regioselective phosphorylation 18:399 Regioselective reactions 24:3,9,10,742 O-methylation 24:742 radical carbocyclization 24:3 reduction 24:9,10 Regioselective reduction 6:289,290 Regioselective tosylation 12:218 Regioselective [3-glycosylation 10:477 Regioselectivity 4:118,142,372,373,391 in Diels-Alder reactions 4:584-586 of C-aryl glycoside 11:142 of 2-substituted 1,2,3,4tetrahydronaphthalene acetate 11:118 of Claisen rearrangement 4:368, 369 of Friedel-Crafts alkylations 4:391 ofhydroboration 4:116 Regiospecific 22:225 Regiospecific cleavage 11:267,268 of oxirane ring 11:267,268 Regiospecific enolization 12:84 Regiospecific lithiation 6:509,510 of 1-(phenylsulfonyl) indole 6:509,510 Regiospecific oxidation 6:508 of ellipticine 6:508 17-oxoellipticine from 6:508 Regiospecific sulphonation 4:633 of camphor 4:633 Regiospecificity 4:391 of Friedel-Crafts allylations 4:391
Regularoside B 15:51,52 Regularosides A,B 7:290,293,299 Reich-Sharpless reaction 24:194,195 Reichstein substance-S 9:416,417 21-acetate of 9:417 17,21-diacetate of 9:416,417 3-enol-17,21-triacetate of 9:416, 417 17-monoacetate of 9:416,417 Reidispogiolide C 26:1209 Reidispongia 26:1175 Reidispongia coerulea 26:1207,1208 Reidispongiolide A-C 26:1207,1208 Reimer-Tiemann reaction 2:67,68 ~3C-Relaxation measurements 2:67,68 Reinera sp. 25:723 related compounds of 25:538 Reissantiatrol oxide 5:744,748 Reissantiol oxide 5:744,748,750 Relative configuration 5:704,39-59,261 of antibiotics 6:261 of bisabolones 8:39-59 o f (+)-castanospermine 12:332 of 2-hydroxyindolizidines 12:284 of lienomycin 6:261 ofpimaricin 6:261 of pyrrolidine venom alkaloids 6:435 of (-)-slaframine 12:309,310 of(-)-swainsonine 12:313 oftetramycines A,B 6:261 of tetrols 5:705 Relative confiuration 23:188 of pseudodistomin A 23:188 ofpseudodistomin B 23:188 Relative stereochemistry 9:18-23 of taxanes 12:191 Relaxation 24:910-913 effect of cholecystokinin 24:910-913 ~H-Relaxation measurements 2:67,68 of phenol 8:33,34 IH-Relaxation measurements 2:67,68 of phenol 8:33,34 Relayed COSY 9:151,152 Relectional symmetry 7:3
691 Remote functionalisation 7:166-168 of camphor 4:625-697 Remote oxidation 4:645,646 of (+)-bornyl acetate 4:645,646 of (+)-camphor 4:645,646 of (+)-isobornyl acetate 4:645, 646 Renal cancer 23:294 Renal dipeptidase 13:84 insensitivity with 13:84 Renealmia alpinia 25:266 Renghol 9:319 Rengyo 16:576 antibacterial effect of 16:576 as antinflammatory agent 16:576 synthesis of 16:587-588 Rengyolone 16:616 Rengyoside 16:584-587 synthesis of 16:584-587 Rengyoside A 16:587-588 synthesis of 16:587-588 Rengyoside B 16:584-587 reduction of 16:587 synthesis of 16:584-587 Rengyoside C 16:588-592 synthesis of 16:588-592 Reniera sarai 22:30 Reniera sp. 21:266 1,6-D imethyl-7-methoxy-5,8dihydroisoquino-line- 5,8-dione from 21:263,266 renierone from 21:265 Renieramycin A 10:97-100 synthesis of 10:97-100 Renieramycin analogues 10:100 Renieramycin B 10:79,97 Renieramycin C 10:79,97 Renieramycin D 10:79,97 Renieramycin E 10:79 Renieramycin F 10:79 Reniformin A 15:112 Reniformin B 15:119,126,133,172 Reniformin C 15:137,145,154,172 Repandine 26:824,826 Repandusic acid (hydrolysable tannin) 29:573 effects on HIV- 1 protease 29:573
Repellent properties 28:395 of Amblyomma variegatum 28:395 Reperfusion injuries 30:224 role of free radicals in 30:224 Replacement of sulfur by oxygen 1:560 by [2,3]-sigmatropic rearrangement of sulfoxide 1:560 Replic plating technique 7:115 Reproduction ofchirality 4:345 Reptoside 29:83 activity in EBV assay system 29:83 Resacetophenone 4:388,389 Rescinnamidine 9:174 Rescinnamine 9:174,19:748;21:488 Rescorcinolic lipids 30:165-167 effects on enzymatic activity 30:165-167 interaction with proteins 30:165-167 Rescorcinolic lipids 30:165-167 interaction with proteins 30:165-167 Resda luteola 26:632 Reserpiline 5:128 Reserpine 1:159;2:369,399,400,415, 283,174,410,13:631,267;18:64 ;21:57 ,84,488;25:538 as immunosuppressive drug 25:538 conversion to 3,4,5,6-tetradehydroreserpine 1:159 from levoglucosenone 14:267 oxidation of 1:159 photochemical oxidation of 1:159 reaction with ceric sulfate 1:159 synthesis of 14:267 synthetic approaches to 3:339,400,415 Resistance-modifiers 30:595 antimalarial drugs as 30:595 Resistant Plasmodium species 30:595 in chloroquine sensitivity 30:595 Resolution 1:319,324-327 diastereomeric 1:585-588 kinetic 1:589 through chiral ketones 1:585-588
692
of ketones 4:342,325 of racemic anthracyclinones 4:319 with Ender's reagent 4:327 with (-)-N-methylephedrine 4:326 with (+)-threitol 4:324,325 Resonance frequency 9:110 of 170 9:110 of 33S 9:110 of 77Se 9:110 of ~25Te 9:110 Resonance Raman spectra 30:540 of carotenoid cation radicals 30:540 Resorcinol 9:341 ;21:522 Resorcinol dimethyl ether 14:692,693 Resorcinolic lipids 30:119,158,160, 162-164 as antifungal fluids 30:160 as growth reulators 30:162-163 as hair restoration-lotion 30:160 used in gingival infections 30:160 Resorcinolic lipids interaction 30:169-172 with phospholipids 30:169-172 [3-Resorcylic acid 13:539 Resortive effect on progenitor cells 25:448,449 Respiration 5:858,859;23:375 coumarin effect on 23:335,353, 356,357,368,376,393,550,553 in birds 5:858,859 Respiratory ailments 24:847 Respiratory depression 30:799 due to analgesic alkaloid 30:799 Respiratory disorder 30:224 role of free radicals in 30:224 Respiratory infection 30:408 Respiratory syncytial virus 30:395 Respiratory toxins 24:1002,1063 Respiratory tract infections 26:50 Herniaria hirsuta in 26:50 Response decay mechanism 25:491 Response modifiers 23:129 biological 23:129 Responsive element binding protein 27:825
Restriction enzymes 13:636 Restrytirol A-C 26:553,558,570,571 Resveratrol 22:609,627;25:546;26:753; 27:430;854,855;28:582 biological activity of 27:430 effects in LLC-bearing mice 28:582 effects on tumor volume 28:582 effects on tumor weight 28:582 Resveratpole 20:782 cis-Resveratrol 22:611,619;26:555,571 trans-Resveratrol 26:560;27:768 homooligomers of 27:768 (E)-Resveratrol 3-O-[3-D-glucoside 23:533 Resveratrol oligomers 26:507-511,513529,533,534;532,556-559 isolation of 26:533,534 pharmacological properties 26:556-559 sources of 26:513-529 trans-Resveratrol oligomers 27:768 Resveratrol tetramers 23:535 Resveratrol trans-dehydrodimer 26:555, 565 Resveratrol trimers 23:534 cis-Resveratrol-O-~-glucoside 22:611, 619 Resveratrolside 26:530,571 Retained placenta 30:597 treatment of 30:597 use of Hernandia moerenhoutiana in 30:597 use of Hernandia nymphaeifolia in 30:597 Reticulatacin 17:270;18:205 hemi-synthesis of 18:219,220 Reticulatamol 18:212 Reticulatamone 18:195,212 Reticuline 11:205 (R)-Reticuline 18:53,54;20:291,292; 22:10 (+)-Reticuline 30:566,595,596 antimalarial activity of 30:595 antiplasmodial activity of 30:596 as platelet aggregation inhibitor 30:594 effect on antiplasmodial activity 30:596
693 (S)-Reticuline 8:53,14:771 Reticulo-endothelial system (RES) 23:129 Reticulose 20:531 Retigeranic acid 3:5,6,8,67 synthesis of 3:10 retroaldolization 3:74,75,100, 101 retronecine 3:54 (-)-Retigeranic acid A 13:23-25;16:227 from Loberia retigera 13:22 X-ray crystal structure of 13:22 Retigeranic acid B 13:23-25 (11Z)-Retinal 10:150 Retinal 10:153;29:111;30:520,521 activity in AM bioassay system 29:111 in visual signal transduction 30:520 structure of 30:521 13-cis-Retinioic acid 4:526,531-534 synthesis of 4:531-534 Retinoic acid 10:154;29:111;20:514; 25:59,60,515 ;30:493,498,521 activity in AM, EBV, skin-1, ODC bioassay systems 29:111 ester of 30:521 in cell differentiation 30:521 in development 30:521 in growth regulation 30:521 structure of 30:521 via nuclear receptors 30:521 trans-Retinoic acid 4:527 Retinoic acid analogues 4:534,536 synthesis of 4:534,536 Retinoid chemistry 28:69 recent progress in 28:69 Retinoid retinol 29:111 activity in AM, EBV bioassay systems 29:111 Retinoids 22:126;25:44,515;29:110 in mammary cancer 29:110 in urinary bladder cancer 29:110 Retinol 30:520 cleavage of 30:520 13-cis-Retinol 4:513-534 synthesis of 4:513-534 Retinol (vitamin A) 28:69 in mammalian food 28:69
Retinol acetate 29:111 activity in AM bioassay system 29:111 Retinol palmitate 29:111 activity in AM bioassay system 29:111 Retinyl phosphate 8:78 synthesis of 8:78 Retro aldol process 19:194 Retro Diels-Alder cleavage 5:634; 9:295,300 Retro Diels-Alder fragmentation 4:40, 41 to secodine 4:40,41 Retro Diels-Alder reaction 4:614,615; 24:721,722 synthesis of actinidine 4:614,615 synthesis of ~-caryopterone 4:612-614 synthesis of crotepoxide 4:162 synthesis of epiepoformine 4:612,613 synthesis of epiepoxydon 4:610 synthesis of epoformine 4:612 synthesis of epoxydon 4:610 synthesis ofligularone 4:615 synthesis ofpetasalbine 4:615 synthesis of phyllostine 4:610 Retro Michael reaction 14:748 Retro[2+2]cycloadition 19:221 Retro-aldol degradation 12:216 Retro-aldol fragmentation 12:212 Retro-aldol reaction 7:286,288,291; 10:168,303,329;18:284,285 Retro-aldolisation 4:4,7,56,14:180 Retro-Diels-Alder fission 21:556 Retro-Diels-Alder reaction 21:387 Retroene 24:29,30 Retroene reaction 11:46,47;16:246 Retrograde aldol reaction 6:78 Retrograde Michael reaction 6:173,187, 199,200 Retrojusticin B 26:194 Retro-Mannich reaction 1:157,158; 6:497 ;10:99,333,682;11:55,56; 13:181,397,423,460;18:18 of O-quinol acetate 16:521 Retro-Michael elimination 12:490
694
Retronecic acid 1:264-266 synthesis of 1:264-266 Retronecine 8:222,223;13:484,485; 14:568;19:489 coupling reagent 1:268,269 chiral synthesis of 19:489 synthesis of 1:228,231,232, 234-239,241,246,249,325,326 unnatural monoesters of 1:268 Retro-Prins reaction 16:248 Retroprotoberberines 1:218,219 biogenesis of 1:218,219 Retrorsine N-oxide 22:13 Retrospective study 23:17 Retrosynthetic analysis 27:189 ofhemiacetal ethers 27:189 Retroviral enzymes 30:397 inhibitor of 30:397 Retroviruses 30:394,397,408 causative agent of immunodeficiency syndrome 30:394 inhibitor of 30:408 Retro-Wittig reaction 18:78,176 Rett's disorder (RTT) 30:372,373,384 by mutations in MECP2 gene 30:373 genetic basis of 30:373 Retulinal 1:36 Retuline 1:38,39 Retusine 23:798 Reutericyclin 28:127 as antibiotic 28:127 Reverse Michael addition 3:473,25 Reverse transcriptase 4:267;25:941; 30:226,395,397 role in HIV replication cycle 30:226 role in viral replication 30:397 Reversed-phase HPLC 5:651-659; 21:542 Reversible inhibitors 7:40 glycosidase inhibitors as 7:40 Reversion 4:123 of asymmetric induction 4:123 Reymosin 7:232;27:555 Reynoutna japonica 22:608 Reynoutria japonica var. typica 24:273
Rh (II)-catalyzed carbenoid insertion 13:501,502 Rhabdastrella sp. 21:273 Rhabditis sp. 26:432,488 a-Rhammosidation reaction 8:359 Rhamnaceae 25:469;27:3 Rhamnazin 7:228;26:314 Rhamnetin 29:578,581 effects on ACE 29:581 effects on aminopeptidase N 29:578 Rhamnocitrin 7:228 Rhamnomannans 5:303,305,309,325 Rhamnopyranosides 5:657 L-Rhamnopyranosyl 15:7 c~-L-Rhamnopyranosyl (1-2)-~-Larabinopyranosyl)-3-O-acetyloleanolate 21:732 [3-L-Rhamnopyranosyl glycosides 7:70 9-(oc-L-Rhamnopyranosyl purines 4:233 synthesis of 4:233 L-Rhamnose 1:261,387,144,181 synthesis of 1:510 furaneol from 13:318 Rhamnose 22:312 L-Rhamnose 27:506 Rhamnosidase 7:70 c~-L-Rhamnosidase 7:70 from Aspergillus niger 7:70 Rhamnosidation 8:359 of cholestanol 8:366 of cholesterol 8:366 ot-Rhamnosides 8:359,366 [3-Rhamnosides 8:366 3-O-Rhamnosil-kaempferol 22:355 Rhanmosyl chloride 8:359-362,368,369 (2,3,4-Tri-O-benzyl-c~-Lrhamnosyl chloride) thermal glycosidation with 8:359-362, 368,369 3-O-Rhamnosyl galactoside 22:634 (- )-( tra ns-4 '-Rhamno s yl o x y-3 '-me t ho x ycinnamoyl) lupinine 15:521 from Lupinus luteus 15:521 (-)-( cis-4 '-cz-L-Rhamnosyloxycinnamoyl) epi-lupinine 15:521 from Lupinus hirsutus 15:521
695
(-)-( trans-4'-o~-L-Rhamnosyloxycinnamoyl) epilupinine 15:521 from Lupinus hirsutus 15:521 (- )-( tra ns-4 '- Rhamno s yl o x y-c inna mo yl ) lupinine 15:521 Rhamnosyl-quercetin 25:541 3-0L-Rhamno-c~- 1,4-D-galacturonan 27:506 Rhamnus catartica 22:583 Rhamnus frangula 22:583 Rhamnus purshiana 22:583 Rhaponticin 22:630 Rhatannins 17:439 Rhazia stricta 5:135,140-144,150,152, 153,165,167,169,176,178;29:362 Rhazigine 5:144 biogenesis of 5:144 Rhazimanine 9:170,172 Rhazimine 5:180,181 Rhazine (E-akuammidine) 13:403 Rhazinilam synthesis 29:371,401 by Levy and co-workers 29:373 by Smith 29:371 Emde degradation in 29:373 mCPBA oxidation in 29:373 by Baudoin-Gueritte 29:407 by Gueritte and co-workers 29:407 by palladium-catalyzed biaryl coupling 29:407 by Smith 29:402 challenges in 29:401 iminium intermediate in 29:405 of (-)-rhazinilam by Sames 29:404,405 of (+)-rhazinilam by Magnus 29:406 of phenyl-pyridine analogues 29:410 of phenyl-pyrrole analogues 29:406 quaternary C-20 stereogenic center in 29:403 racemic type of 29:401 rhaziniliam analogues obtained by Suzuki-Miyaura biaryl coupling 29:410 Schiffbase formation in 29:404 Suzuki coupling in 29:409
using Gupton methodologies in 29:406 using the Barton-Zard reaction in 29:406 (-)-Rhazinilams 29:362 absolute configurations of 29:362 analogues of 29:364 as axially chiral phenyl-pyrrole 29:362 as microtubule poisons 29:364 leuconolam as 29:363 3-oxo- 14,15-dehydrorhazinilam as 29:363 3-oxorhazinilam as 29:363 rhazinal as 29:363 semi-synthesis of 29:363 synthesis of 29:364 tubulin-binding properties of 29:364 X-ray structure of 29:363 Rhazizine 5:178-180 Rheedia gardneriana 30:207 antinocicieptive effect of 30:207 Rheedia madrunno 22:658 Rheum emodi T. 30:327 physcion from 30:327 Rheum palmatum 17:421,439;27:849, 850;29:579 Rheum spp. 29:589 Rheumatism 26:50;30:192,691 Herniaria hirsuta in 26:50 use of non-steroidal antiinflammatory drugs (NSAIDs) 30:192 use of prostaglandin inhibitors 30:192 Rheumatoid arteriosclerosis 30:70 Rheumatoid arthritis 21:152;22:310; 26:170,486;30:70,204,225 in treatment of CPH82 26:170 in rats 30:204 reagent-induced 30:204 treatment of 30:225 use of Kalopanax pictus in 203 rHFPtase inhibitor 24:440 cembranolide as 24:439 Rhinacanthin E 26:191,226 Rhinacanthin F 26:191,226
696
Rhinacanthus nasutus 26:226;29:747 rhinacanthin E&F from 26:226 Rhinoclaviella sp. 26:673 Rhinotermitidae 19:118 Rhipicephalus appendiculatus 28:396 Rhipicephalus evertsi 28:396 Rhipicephalus genera 28:404 Rhipicephalus haemaphysaloides 28:405 Rhipicephalus sanguineus 28:400 Rhipicephalus spp. 28:407 Rhipocephalus phoenix 18:689 Rhizobia 25:395 Rhizobiaceae 25:379 Rhizobium 22:345 Rhizobium lipopolysaccharides 26:931 Rhizobium meliloti 25:395 Rhizobium symbiosis 25:659 Rhizoctonia 9:203 Rhizoctonia leguminicola 7:11 ;19:468; 27:254,255,515 (-)-( 1S,2R,8aS)-indolizidine- 1,2diol from 12:303 slaframine from 12:306 (-)-swainsonine from 12:313 Rhizoctonia solani 7:190;13:233,234; 21:182,187,197,199,202,205,219, 220,229,213,223,238;22:459,489, 499;26:404, Rhizophora apiculata 7:180-182,189, 194,195 Rhizophora mangle 7:175 Rhizophora mucronata 7:176,180,188, 189,192,194,195 Rhizophora sp. 7:176 Rhizophora stylosa 7:179-181,193 Rhizophoraceae 22:718,720 Rhizophorine 7:192 Rhizopogon 29:271 Rhizopus arrhizus 17:629;23:20,23,25 Rhizopus delemar 2:322,341 Rhizopus nigricans 17:629;24:74,76; 25:253,261,318 Rhizopus niveus 2:322,341 glucoamylase from 7:49 Rhizopus oligosporus 26:1007 Rhizopus sp. 2:322,323,276 glucoamylase from 2:341 Rho plus values 17:553
Rhodiola sachalinensis 29:590 Rhodiola sacra 29:590 Rhodiosin (flavonol glycoside) 29:589 effects on PEP 29:589 Rhodium 6:424 catalytic hydrogenation with 6:424 Rhodium (1) 1:177-179 decarbonylation by 1:177-179 Rhodium catalyst 4:436 in carbene insertion reaction 4:436 Rhodium catalyzed isomerization 4:22,23 Rhodium III chloride 22:222 Rhodnius prolixus 26:187,230;22:383 Rhodobacter sphaeroides 28:521 Rhodoccus rhodocrous 8:299,302,303, 312 muconolactone methyl isomerase from 8:307 Rhodococcus equi 22:282 Rhodococcus erythropolis 25:150 Rhodococcus rubropertinctus 25:162, 165,166 Rhododendron arboretutn 29:571 Rhododendron chrysanthum 20:17 Rhododendron cinnabarinum 29:585 Rhododendron Crrugineum 20:17 Rhododendron ,,trsutum 20:17 Rhododendron luteum 20:17 Rhododendron molle 13:660 rhomitoxin from 13:660 Rhododendron ponticum 20:17 Rhododendron simsii 20:17 Rhododendron sp. 25:242 Rhodomelol 4:712,725 (-)-y-Rhodomycinone 14:14-17 enantioselective synthesis of 14:14-17 [3-Rhodomycinone 4:347,348 enantioselective synthesis of 4:347,348 Rhodomycinones 4:345-349 synthesis from amino acids 4:345-349 synthesis from hydroxy acids 4:345-349 Rhodophida bifida 20:356
697 Rhodophin glucoside 30:521,522 structure of 30:522 Rhodophyllis membranacera 5:410 Rhodophyta 27:735 Rhodopin 18:823;20:591,592 Rhodosamine 4:317 Rhodotorula acuata 21:391 Rhodotorula glutinis 5:292,309 Rhodotorula lactosa IFO1424 13:233 Rhodotorula minuta 5:292,299 Rhodotorula peneaus 5:292 Rhodotorula rubra 7:340;26:673 torularhodin from 7:340 Rhodotorula sp. 5:291,292 Rhodotoxin 20:17 Rhodoxanthin 20:118 Rhoeadine 1:218,219 biogenesis of 1:218,219 Rhoeadine alkaloids 1:187,189 from indenobenzazepines 1:212-214 from spirobenzylisoquinolines 1:212-214 synthesis of 1:212-217 Rhoeagenine 1:213,213 synthesis of 1:213,213 Rhoifolin 25:594,595;29:573 effects on HIV- 1 protease 29:573 Rhoiptelea 26:905 Rhoiptelea chiliantha 26:895,902 Rhoiptelol A&B 26:895,902 Rhombenone 24:456 FPTase inhibition by 24:456 Rhomitoxin 13:660 Rhone-Poulenc 28:71 vitamin A synthesis by 28:71 Rhopaloeides sp. 25:698 Rhopaoloic acid A B and C 25:698 RHPLC 9:333 Rhus cotinus 29:579 Rhus rhodantherma 29:579 Rhus sp. 9:337;27:840 Rhus succendanea 9:319 Rhus vernicifera 9:318,328,329,331,339 Rhus(toxicodendron) 9:318,328,339 Rhus(toxicodendron) diversilobum 9:318 Rhus(toxicodendron) radicans 9:318
Rhynchoidomonas 2:298 Rhyncholacis penicillata 26:471 Rhynchophylline 25:26 Rhynchophylline ent-allo A- 17demethoxy 5:127 Rhynchophylline-type alkaoids 5:83,84 ent-allo-A- 17-demethoxyrhynchophylline (eatharinensine) 5:83,84 Rhytidoponera aciculata 5:224,229,254 Rhytidoponera chalybaea 5:224,225, 229,246,254 Rhytidoponera metallica 5:224,226, 229,243-247,251,252,254,255,262, 266;15:384 Rhytidoponera sp. 5:230,247 Rhytidoponera victoriae 5:223,224,229, 251,254 Ribavirin 24:490;25:31 Ribenol 25:250 Ribes nigrum 20:721 Ribes rubrum 27:839,840 extracts of 27:839 Ribes sanguineum 27:839 extracts of 27:839 Ribi cell fractionator 19:694 Ribitol 4:510 synthesis of 4:510 Riboflavin 20:730,773;26:1007 D-Ribofuranoses 6:363,364 phosphorus analogs of 6:352,355,359,363-366,368 synthesis of 6:363,364 [3-Ribofuranosyl heterocycles 10:369, 370 Ribofuranosylethynes 10:359 D-Ribo-hexitol 6:357,358 C2-P bond analog of 6:357,358 D-Ribo-hexofuranose 6:369 2-azido-D-arabino-hexofuranoses from 6:369 from D-allofuranose 6:369 R-Ribonolactone 19:357 L-Ribonolactone 19:359 D-Ribonolactone 6:292 (4S)-hydroxymethyl butanolide from 6:292 Ribonuclease T ~ 4:271 gene synthesis 4:271
698
Ribonucleic acid 22:28 Ribonucleotide resin 4:301 preparation of 4:301 Ribooligonucleotides 4:268 synthesis of 4:268 Ribosomal process 22:29 Ribosomal protein $6 kinase 12:390 Ribosome-inactivating proteins (RIPs) 24:523 dimeric 24:523 single chain (homologous) 24:523 Ribostamycin 11:216-218 biosynthesis of 11:216-218 by Streptomyces ribosidificus 11:216 from glucose 11:216-218 Riboypyranoses 6:366,367 Dsynthesis of 6:366,367 D-Riburanitrose 19:118 Riccardin A 2:282,283 Riccardin B 2:282,283 Riccardin C 2:282,283 Riccardins 2:109,282,283 distribution in Hepaticae 2:283 structure of 2:109 Rice blast disease 1:404,529 Richardella dulcifica 27:39;29:605 miraculin from 27:39 Ricinoleate 26:361 Ricinoleic acid 9:387;21:197;30:193 analgesic action of 30:193 Ricinus communis L. 22:531;28:400; 30:193 ricinoleic acid from 30:193 Rickettsial pathogens 28:394 Cowdria ruminantium as 28:394 Riddellinne 7:23 Ridentin 7:231,232;27:566 Rieke's zinc 13:146 Rifampicin 9:37,38,431-435,439-443; 12:39-47,37,38;20:714 Rifampin 2:424;23:59 synthesis of 12:39-45 total synthesis of 12:46,47 Rifamycin 23:52 Rifamycin B 21:421;23:55,86 related compounds of 23:55 ansa moieties 23:86
Rifamycin B producer 23:88 Rifamycin G 23:57 Rifamycin 0 23:82 Rifamycin R 23:57 Rifamycin S 1:521-528,10:150,153; 23:57,60,84 absolute configuration of 23:85 preparation of 23:57,60,84 21-epi-Rifamycin S 23:56 Rifamycin W 10:153;23:60 Rifamycin W-hemiacetal 23:61 Rifamycin W-lactone 23:61 Rifamycin Z 23:61 Rifamycins 9:431-435,439-443;21:420, 434;23:5,79 carbon- 13 NMR spectral studies of 23:55 Rifamycins B 21:421 Rifamycins L 21:421 Rifamycins O 21:421,422,425 Rifamycins S 21:421,422,425 Rifamycins SV 21:421,422,425 Rifamycins Y 21:421 Rifamycin-type macrolides 24:545,546 antiviral microbial-derived compound 24:545,546 Rift valley fever infection 30:411 treatment of 30:411 Rigidin 10:247;23:242,245 Rigidone 23:166 Rimantadine 24:489 Rimantidine 27:108 for treatment of influenza in infections 27:108 Rimsulfuron 25:669 Ring (C)-homoberberin analogue 6:496 spiro-isoquinoline derivative from 6:496 Stevens rearrangement of 6:496 Ring B-homoberberine analogue 6:496 dibenz [c,g] azacycloundecine 6:496 derivative from 6:496 reaction with dimsyl sodium 6:496 Ring cleavage 16:139 of (+)-9,10-dibromocamphor 16:139
699
Ring cleavage reactions 4:667-673 of camphor 4:667-673 of camphor derivatives 4:667-673 Ring closure 11:10 by Mitsunobu procedure 11:10 Ring construction 3:226,310;6:474, 475,482 by diazotization 3:225,226 in benzazocine derivative synthesis 6:468-471 in benzoxazocine derivative synthesis 6:468-477 intramolecular 11:42,43 nine-membered rings from 6:474,475 of furanosyl nucleoside 10:592-595 of lactone triflate 10:605 oxetanocin A synthesis by 10:592-595 thermal 3:310 to eight-membered rings 3:67,77 to nine-membered rings 3:76 to oxetane-2-carboxylate 10:605 Ring destruction 6:468-471,475-497 by CNBR-induced reaction 6:476,477,484,486 by chloroformate ester-induced reaction 6:477 by photosolvolysis 6:475,476 in benzazocine derivative synthesis 6:468-471 in benzoxazocine derivative synthesis 6:468-471 nine-membered rings formation by 6:468-471 of tetrahydroisoquinoline systems 6:477 Ring enlargement 10:232,233 by migration 10:232,233 by rearrangements 10:232,233 Ring expansion 6:468,472,477,478; 11:6,7,28-31,109 regioselective 11:6,7 2,4-benzoxazocine derivatives from 6:469 in aporphine alkaloids 6:469
in (+)-spiniferin- 1 synthesis 6:73,74 of erythrinan-3-one 6:477,478 of ct-narcotine N-oxide 6:468 Ring interconversion 6:468-475,478, 482-497 in benzoxazocine derivative synthesis 6:468-471 nine-membered rings from 6:468-471 Ring opening 12:411,413 2-amino alcohol by 12:411,413 of oxirans 12:411,413 with nitrogen nucleophiles 12:411,413 Ring transformation 10:303-336 Ring transposition procedure 6:374,375 Ring-phosphino-D-xylopyranoses 6:374,375 synthesis of 6:374,375 Rishitin 26:460 Ristocetin 10:657-659;26:366 Riterella rubra 23:241 Ritonavir 24:489 inhibitor of HIV-protease 24:489 Ritter reaction 11:281,282 Hg(II)-mediated 11:281,282 Ritterazines 18:881-884 synthesis of 18:900-902 Ritterella sigillinoides 5:253;25:782, 816;28:633 Ritterella tokioka 18:881,882 Rivulalactone 20:473 Rizophora apiculata Blume 30:396 Rizophora mucronata 30:396 RJ bioassay 30:807,814 activity of deltorphin B in 30:807 of glycopeptide 30:814 RNA 13:257-294 antisense 13:257-294 synthesis of 13:284-285 T7RNA polymerase 4:306 enzymatic ribonucleotide synthesis 4:306 m-RNA polymerase 7:387 RNA polymerase I 13:258,259 RNA virus 30:394 arenavirus type of 30:394
700
bunyavirus type of 30:394 coronavims 30:394 influenza virus 30:394 measles virus 30:394 parainfluenza virus 30:394 picomavirus type of 30:394 rabies virus 30:394 reovirus type of 30:394 rotavirus type of 30:394 RNA-dependent RNA polymerase activity 30:407 virion-associated 30:407 RNA-directed DNA-polymerases 29:127 inhibition by Sf-9 cell line 29:33 RNase II 13:289,290 RNase III 13:260 Robinia pseudoacacia 25:93;27:374; 29:572 Robinin (kaempferol 3-O-galactosylrhamnosyl-7-O-rhamnoside) (flavonol O-glycoside) 29:573 effects on HIV- 1 protease 29:573 Robinioside A 25:97 Robinioside B 25:96 Robinioside C 25:96 Robinioside D 25:96 Robinioside E 25:96 Robinioside F 25:96 Robinioside G 25:96 Robinioside H 25:96 Robinioside I 25:95 Robinioside J 25:95 Robinson annelation 1:17-21,29,81, 446,478;6:18,19:29,30,56,57,58,55, 148,182;11:33,78,93-96,108;14:678, 679;24:201,206,207,208 bicyclic enone from 14:678,679 of (+)-carbomenthone 6:547,548 of 2-carboethoxycyclohexanone 14:678,679 of ethyl vinyl ketone 14:678,679 of cycloheptenone enolate 6:29, 30 of ethyl vinyl ketone 6:19 of 2-methyl- 1,3-cyclohexadione 6:19 trimethyl decalone by 6:19,20
Robinson annulation reaction 14:406-425 chiral sesquiterpenes from 14:406-425 Robinson-Schopfcondensation 1:294, 295 Robustic acid 4:382,384;27:844 by C-prenylation 4:382,384 from desoxybenzoin 4:382,384 Rocaglamide 16:565 antileukaemic activity of 16:565 synthesis of 16:565 Rocaglaol 26:220 Rocaltrol 9:513 Roche acid 1:471 Rodobyrum giganteum 2:277 Rodophilia bifida 26:615 Roemeria sp. 2:253 (-)-Roemerialinone 2:257,512 Roeperanone 30:621 structure of 30:621 ROESY 21:764,767;23:27 ROESY correlation 30:586 of (7R,8S,7'R,8'R)-(+)-7'-acetyl5'-methoxypicropodophyllin 30:586 ROESY experiment of 30:646 structure of 30:646 ROESY spectrum 17:129 of oligosaccharides 17:129 Rofecoxib 30:192 as COX-2 inhibitor 30:192 Rohituka-3 20:492,493 Rohitukine 21:130,131,134,135, 141,147,151-153 Role 27:797 of cholecystokinin 27:797 of gastrin 27:797 of protein phosphorylation 27:821 Rollidecin 26:793 Rollinia emarginlu 26:793 Rollinia mucosa 18:208 rolliniastatin from 18:208 Rollinia ~ylvatica 9:399 Rollinia ulei 27:880 Rolliniastatin I 17:262,272 Ent-Rolliniastatin-1 18:210,211 synthesis of 18:210,211
701
Rolliniastatin- 1 26:793 Rolliniastatin-2 18:208 from Rollinia mucosa 18:208 synthesis of 18:208,209 Rollinicin 17:277 Rollinone 17:278 Romalea microptera 9:488,489 Romneya genera 27:163 Roosters 27:302 Ropholic acid A 25:698,699 Roridin D 30:736,737 structure of 30:737 Roridin E 26:811,812 Roridins 30:743 antiviral activity of 30:743 ROS (Reactive Oxygen Spp.) 27:504, 505 ROS Scavenging activity 22:317 of flavonoids 22:317 Rosa bourbonia 25:132 Rosa damascena 7:104,107,109-112, 125;14:425 (x-damascenone from 14:425 f3-damascenone from 14:425 y-damascenone from 14:425 ct-damascone from 14:425 [3-damascone from 14:425 ),-damascone from 14:425 6-damascone from 14:425 Rosa damascena cv. trigintipentalla 7:125 Rosa davurica 23:404 Rosa rugosa 23:397,404;29:83 Rosa sp. 7:102,105,107,108,125 Rosaceae 23:396,404;30:610 acylphloroglucinols from 30:610 Rosamine 5:160 Rosane diterpenoids 20:474 of Vellozia candida 20:474 Rosaramicin 5:613 Rosaranolide 11:160 synthesis of 11:164 Roscoe 9:321 Rose bengal 1:190 Rose oil components 14:425-431 synthesis of 14:425-431 Rose oil ketones (damascones) 14:425
Rose oxide 25:138 trans and cis 25:138 Rosefuran 19:174 Rosenolactone 19:402 synthesis of 19:402 ROSEY 6:140 Roshenin A 23:416 Roshenin B 23:416 Roshenin C 23:416 Roshenin D 23:416 Rosibiline 9:183 Rosicine 5:170,171 biogenesis of 5:171 Rosiridin (monoterpene glycoside) 29:590 effects on PEP 29:590 Roskamp condition 14:653 Rosmanol (abietane diterpene) 29:575 effects on HIV-1 protease 29:575 Rosmanol (abietane diterpene) synthesis 29:575 from camosolic acid 29:575 Rosmarinecine 1:29,7:15 (-)-Rosmarinecine 19:149 isolation of 19:149 Rosmarinic acid 7:96;25:921 ;28:262; 29:581,582 effects on ACE 29:581 effects on collagenase 29:582 from Coleus sp. 7:96 in culinary herbs 28:262 in mixed herbs 28:262 in stuffing 28:262 Rosmarinus 29:579 Rosmarinus officinalis 21:599;29:587 Rosmarinus sp. 21:599;26:746;29:582 Rosthorin A 15:123,139 13C-NMR of 15:130,156 from Rabdosia coesta 15:171 from Rabdosiajaponica 15:172 from Rabdosia rosthornii 15:174 ~H-NMR of 15:116,147 Rosthornin B 15:119 13C-NMR of 15:133 from Rabdosia rosthornii 15:174 ~H-NMR of 15:126
702
Rotation Locular Counter-Current Chromatography (RLCC) 7:429; 24:137 Rotational correlation time 2:61,62 Rotational isomers 27:340 structure of 27:340 Rotational strength 2:145 Rotational symmetry 7:4 Rotavirus gastroenteritis 30:406 treatment of 30:406 Rotaviruses 30:406 Rotenoids 24:218-228,799;27:893 Rotenolone 28:436 as complex I inhibitor 28:436, 437 Rotenone 7:193;26:473;28:436 as complex I inhibitor 28:436, 437 Roteopsis furnensis 29:89 Rothin A,B 7:232 Rothrockene 7:208,209 from Artemisia tridentata sp. nothrockii 7:208 Rottlerin 27:853,854 Rotundifuran 29:101 activity in APO bioassay system 29:101 Rous sarcoma 5:592 Roxbin A 23:404 Roxithromycin 13:169,183 Roylea calycina 25:252 Royleanone 14:684,692;15:173 from Rabdosia lophanthoides var. gerardiana 15:173 RPR113228 24:437 structures of 24:437 R-Solanidine 23:575 RTK tyrosine kinase 25:545 RT-PCR analyses 28:323 of tumor necrosis factor TNF-c~ 28:323 Rubella virus replication 30:374,409 autistic features in 30:374 blocking by 30:409 inhibitory effect on 30:409 Ruberythric acid 26:629,640,642, 657,674 Rubescensin C 15:174 from Rabdosia rubescens 15:174
Rubescensin D 15:163,164,167 13C-NMR of 15:165 from Rabdosia rubescens 15:174 ~H-NMR of 15:164 Rubia akone 24:304,307 Rubia cordifolia 10:640;19:776;24:273, 304,307 Rubia spp. 24:304 Rubia teep 26:675 Rubia tinctorum 24:304;26:629-632, 638,639,641,643,644,647,648,650, 653,656,657,658,666,675-677 anthragallol from 26:657 lucidin from 26:657 munjistin from 26:657 mutagenic activity of 26:675 nordamnacanthal from 26:657 pseudopurpurin from 26:657 purpurin from 26:657 rubiadin from 26:657 xanthopurpurin from 26:657 Rubiaceae 21:97,124,153;25:180 Rubiadin 26:657,664,666,676 Rubiadin 3-~-primeveroside 26:657 Rubiadin glucoside 26:657 Rubiadin-l-methyl ether 26:806 Rubianin 26:664 Rubiflavin A 11:136 Rubixanthin 20:727 Rubottom epoxidation 11:75 Rubottom oxidation 12:215 Rubradirin 23:54,68,88 ansa moiety of 23:88 Rubradirins 9:438,19:118 Rubrolides A 25:789,790 Rubrolides B 25:789,790 Rubrolides C 25:789,790 Rubrosides A 25:763 Rubrosides B 25:763 Rubrosides C 25:763 Rubrosides D 25:763 Rubrosides E 25:763 Rubrosides F 25:763 Rubrosides G 25:763 Rubrosides H 25:763 Rubus ellipticus 22:531 Rubus foliolosits 25:251
Rubus fructicosus 20:721 Rubus ideans 20:721
703 Rubus sp. 21:535 Rubus suavissimus 15:16,18;27:13,14,
22-24 desglucosylstevioside from 15:14 ent-Kaurene from 27:22 labaneglycosides from 27:22 rubusoide from 27:13 rubusoside from 15:14 steviol 13-O-[~-D-glucoside from 27:13 suavloside A from 27:14,22 suavioside B from 27:14,22,23 suavioside G from 27:14,22,24 suavioside H from 27:14,22,24 suaviosdie I from 27:14,22,24 suavlosdie J from 27:14,22,24 Rubusoside 15:18;27:13,22,23 from Rubus suavissimus 15:18 structure of 27:23 Rudea aurea 25:93 Rudivirus 30:409 Rufescine 1:167 Rufigallol 25:349,350,351 1,2,3,5,7-hexahydroxy anthraquinone 25:349 Rugosanin 15:142,151,159,174 13C-NMR of 15:159 from Rabdosia rugosa 15:174 IH-NMR of 15:151 Rugosin D 23:403,404,407 Rugosin E 23:404,407 Rugosin F 23:403,404 Rugosin G 23:404 Rule 4:568,587 endo-in Diels-Alder reactions 4:586,587 Rule of Ruzika 25:130 Rumex 22:634 Rupestomic acid 7:237 Rupicolin A 7:235;27:582 Rupicolin B 7:235;27:582;29:90 activity in CRO assay system 29:90 Rupin A 7:235 Rupin B 7:235 Ruscogenin (triterpene) 29:587 effects on pancreatic ELA 29:587
Ruscus aculeatus 29:587
Rusmarinecine 22:183 (+)-Ruspolinone 13:477 Russula sp. 17:153 Russula subnigricans 25:765 Russulaceae 26:461 Russulares 17:200 Russuphelin A 25:765 Russuphelin B 25:765 Russuphelin C 25:765 Russuphelin D 25:765 Russuphelins 25:757 Ruta chalespensis 7:427;22:531 for convulsions 22:531 Ruta graveolens L. 22:531 for epilepsy, hysteria, convulsions and fits in children 22:531 Ruta tuberculata 22:531 Rutaceae 21:3,373,374,583,611 ;27:164, 377,361,372,375 Rutaecarpine 24:296 Rutein 30:523 in human retina 30:523 Ruthenium (III) chloride 12:162 Ruthenium tetraoxide 1:27,28;22;230 Ruthenium-catalyzed oxidation 12:175 Rutin 7:228;22:166,317,323,424,645; 23:747;25:469,608,610,613,615; 26:314,666,747,762,763,768,769; 29:573 ;30:208,747 analgesic effect of 30:208 effects on HIV-1 protease 29:573 structure of 30:747 7-Rutinoside 23:747 3-Rutinoside 5-glucoside 5:658 Ryanodanes 26:850 Ryanodine 21:I6,79,110;22:34 Ryanodine barely 22:34 Ryanodine receptor (RyR) 25:534,535 Ryanodine receptor Ca 2§ channels 25:535 Ryanodine/spiganthineryanoids 26:852, 853 Ryanodine-type compounds 26:850,852 Ryanodol 26:850,856 Ryanodol-14-monoacetate 26:850
704
Ryanodol-type diterpenes 26:852 insecticidal effects of 26:852, 1136 Rydon bromination 6:287,288 Rylander oxidation 12:198 Rzedowskia tolantonguensis 18:756, 764;23:682 33S 9:109-126 natural abundance of 9:110 respectivity of 9:110 resonance frequency of 9:110 spin quantum number of 9:110 Sa mae sarn 28:574 antitumor activity of 28:574 as mild cathartic 28:574 from cassigarol A 28:574 from piceatannol 28:574 from piceatannol acetate 28:574 (+)-cis/trans -Sabinene 11:221,222 biosynthesis of 11:221,222 from geranyl diphosphate 11:221,222 stereochemistry of 11:222 (-)-Sabinene 16:267;27:372 (+)-Sabinene 27:372 Sabinene 7:98-101;9:530;20:16 Saccharide 19:465;24:1006 synthesis of 19:465 uses and derivatives of 24:1006 Saccharomyces bailii 1:689;8:238 Saccharomyces carlsbergensis 19:601; 25:759 Saccharomyces cerevisiae 1:689,694; 2:353,390;3:302;5:418;10:526; 12:103 ;13:302,307,312;17:241; 18:721,722,727 ;20: 470;22:1,264, 398,627,628;23:110,112,115,125, 126,134,474 ;25:143,258,780,782; 26:227,228,618,673,1123,1125, 1126,1129,1283;28:474 dimethyl allyldiphosphate isomerase from 11:201 streptovaricin C from 23:64 Saccharomyces dobzhanskii 5:287 Saccharomyces drosophila 5:287 Saccharomyces fibuligera 25:308 Saccharomyces kluyveri 26:1127 Saccharomyces lactis 5:287 Saccharomyces lodderi 5:283
Saccharomyces microellipsodes 5:283 Saccharomyces phaseolosporus 5:287 Saccharomyces pretoriensis 5:283 Saccharomyces rosei 5:283 Saccharomyces sake 12:401 Saccharomyces sociasi 5:287 Saccharomyces sp. 5:279 Saccharomyces vager 5:283 Saccharomyces wieckerhamii 5:287 Saccharopolyspora erythraea 22:265 Saccharopolyspora spinosa 28:404 Saccharothrix 12:366,368 bromorebeccamycin from 12:366,368 11-dechlorobeccamycin from 12:366,368 rebeccamycin from 12:366,368 Saccharothrix mutabilis 19:290 Saccharothrix mutabilis subsp, chichijimaensis 10:117 Saccharothrixes 29:230 Saccharum officinale 27:191 Saccharum officinarum 15:3;29:593 Sacchromyces epidermidis 26:1095 Sacchromyces sp. 26:1087 Saccorliza polyschides 25:758 Sacculaplagin 2:81-90 absolute configuration of 2:89 derivative of 2:89 ~H-NMR of 2:82 structure of 2:81-90 sacculaplagin triacetate 2:83-88 13C,IH-COSY spectrum of 2:86 COSY spectrum of 2:83 2D-INADEQUATE spectrum of 2:88 long range 13C,tH-COSY spectrum of 2: 87 NOESY spectrum of 2:84,88 Sacculatal 2:278,279,289 piscicidal activity of 2:289 Sacculatane diterpenoids 2:90278,279 Sacupira branca 29:103 Saegusa oxidation reaction 16:430 Saegusa ring expansion 6:37,38 in tricarboxylic epoxide 6:37 Safety evaluation 27:299 of stevin 27:299 of stevioside 27:299
705
Saffron 26:296,297,299,301-305; 28:313,314,315 anti-tumor activity of 28:314,315 as coloring agent 28:313 uses in medicine 28:313 Safracin A 10:78,79 Safracin B 10:78,79 Safracins 25:826 Saframycin 10:78;23:254;25:826 antibacterial activity of 10:78 antitumor activity of 10:78 synthesis of 10:83-100 transformation of 10:101-103 Saframycin A 10:77-87,101,103;23:256 synthesis of 10:84-87,92-96 Saframycin B 10:77-79,82,86,88-93, 101 Saframycin C 10:77-82,86,97 synthesis of 10:101-103 Saframycin D 10:77-79,82,86 synthesis of 10:101-103 Saframycin E 10:77-79 Saframycin F 10:78,79,82 Saframycin G 10:78,79,82,103 Saframycin H 10:78,79 Saframycin Mxl 10:78,79,101,102 Saframycin Mx2 10:78,79 Saframycin R 10:78,79 Saframycin S 10:78,79,101 Saframycin Y3 10:78,79 Safranal 25:956;26:293,295,296,298, 300,303,306,307 Safronitrile 14:430,431 [~-damascenone from 14:430,431 Sagecoumarin 30:220 isolation of 30:220 structure of 30:220 Sagitol 25:894,895 Sagittaria sagittifolia 29:617 Saikogenin F 27:671 Saikogenin F-triglycoside 21:656 Saikogenins 23:512 Saikosaponin 6 27:674 structure of 27:675 Saikosaponin 8 27:674 structure of 27:675 Saikosaponins 21:611;23:487;24:146; 25:90,474 ;27:660,665,666,667,693 biological activity of 27:693
from Aerial parts 27:665 Saikosaponin acid 21:657 Sainfoin 26:1268 Sainfoin proanthocyanidins 21:523 Sakuranetin 7:207,228;26:802 Salacia 18:741 ;23:651 Salacia campestris 30:639,667 cyclase activity of 30:639 Salacia krausii 30:667,693,694 against bilharziasis 30:693 against dysentery 30:693 28-hydroxyisoiguesterine from 30:667 quinone methides from 30:694 Salacia macrosperma 7:150 salaspermic acid from 7:150 Salacia madagascariensis 30:667 isoiguesterine from 30:667 Salacia oblonga 30:645 uses of 30:645 Salanacea 21:622 Salaspermic acid 7:146,147,167 from Salcia macrosperma 7:150 Salcolene axide 9:534 Salcomine 5:823,824 Salcomine-oxygen 14:780 Salicyclic acid 23:750;25:391,653,655, 659-662,664,666,669;27:63 elicitor of pathogen related genes 27:63 generation of 27:63Salicyclic acids 9:327 Salicylate hydroxylase 25:661 Salicylihalamides A and B 25:728 Salicyloyl ester 5:722,723 ofjaeschkeannadiol 5:722,723 Salimo salar 25:723 (2'S)-Salinixanthin 30:517 structure of 30:517 Salinomycin 11:152 Saliva desoleana 26:407,409,410,411 composition of 26:407,409,410, 411 Saliva officinalis 26:391,403,404 Saliva sclarea 26:395,396,404 composition of 26:404 Salivary peptide P-C 24:906-909 from human saliva 24:906-909 inhibition of arginine induced
706
glucagon release 24:909 potentiation of glucose induced in insulin release by 24:909 (+)-Salivene 16:265 Salix caprea 29:581 Salix fragilis 30:195 salicin from 30:195 Salix petsusu 20:627 Salix purpurea 30:195 salicin from 30:195 Salix sachalinensis 20:613,627,628,631, 641,645 Salix sp. 21:535 Salix viminalis 29:605 Salmonella 12:63;26:1161 Salmonella abortus 28:539 in human macrophages 28:521 in peritoneal carcinomatosis 28:533 phase I trials with 28:539 receptor for 28:520 Salmonella anatum 6:262 O-antigen from 6:262 Salmonella choleraesuis 21:607 Salmonella enteridis 12:401;26:673 Salmonella minnesota 28:537 Salmonella monteyideo 8:102 Salmonella mutagenicity assay 22:682 Salmonella newington 8:101;14:233; 26:1160 O-antigenic polysaccharide from 14:233 Salmonella paratyphi 9:308;26:673 Salmonella schottmuelleri 9:308 Salmonella thompson 8:102 Salmonella typhi 9:308;12:401;21:275, 600;26:673 Salmonella typhimurium TM677 27:305 Salmonella typhimurium 5:440;9:214, 606;12:401 ;20:512;21:585,601,602; 22:616, 623,624,682;23:478;25:837; 26:673,675,676,707,712,722,1002, 1093,1099-1101,1104,1105;28:519 Salmonella typhimurium TA 27:305 Salmonella typhosa 12:401 Salsolane 9:534 Salsolidine 21:84 Salsoline 21:97
Salsolinol 21:84;22:24 Salutaridine 18:54,58,71,73,20:292 (+)-Salutaridine 22:10 Salutaridinol 18:54,55 Salvia 26:172;30:242 flavonoids of 30:242 Salvia acetobulosa 20:673 horrnonone from 20:673 1-oxoferruginol from 20:673 3-oxoferruginol from 20:673 18-oxoferruginol from 20:673 pisiferal from 20:673 sempervirol from 20:673 Salvia aethiopis L. 29:100,690 Salvia blepharophylla 30:246 diosmetin from 30:246 pedalitin from 30:246 Salvia candidissima 20:680,688,691 11-hydroxy- 12-methylabieta8,11,13-triene 11 ~-hydroxymanoyl oxide from 20:691 14-oxoisopimaric acid from 20:688 1-oxoethiopinone from 20:680 1-oxosalvipisone from 20:680 3-oxosalvipisone from 20:680 7-acetyhorminone from 20:660 713-hydroxysandracopimaric acid from 20:688 8,13-di-epi-manoyl oxide from 20:691 candidissiol from 20:680 cryptanol from 20:660 crysoeriol from 20:712 diosmetin from 20:712 ferruginol from 20:660 horminone from 20:660 isopimaric acid from 20:688 manoyl oxide from 20:691 microstegiol from 20:680 montbretyl- 12-methyl ether 20:661 salvipisone from 20:680 Salvia cyanescens 30:244 salvigenin from 30:245 6-hydroxy-7,4-dimethoxyapigenin from 30:245 Salvia desoleana 26:391,406,407, 413-419
707 antiinflammatory activity of 26:416 Salvia divaricata 20:661 6-horminone-18-oic acid from 20:661 6-oxo- 12-methylroyleanone- 18oic acid from 20:661 13-sitosterol from 20:702 oleanolic acids from 20:702 oxoroyleanone-18-oic acid from 20:661 salvinine from 20:660 ursolic acid from 20:702 Salvia dominica 27:377 Salvia forskahlei 20:672,710 Salvia fruticosa 27:376,377 Salvia gilliessi 21:600 Salvia glutinosa 20:707 3-acetoxy-olean-9,11-diene from 20:707 c~-amyrin acetate from 20:707 11-cholest-5-ene-313,7c~-diol- 1one from 20:707 erithrodiol 28-acetate from 20:707 313-hydroxy- 11-oxo-oleana- 12ene from 20:707 313-hydroxy- 11-oxo-ursa- 12-ene from 20:707 7c~-hydroxysitosterol from 20:707 lupeol from 20:707 1-oxo-7cz-hydroxysitosterol from 20:707 oxo-c~-amyrin from 20:707 11-oxo-[3-amyrin from 20:707 oleanolic acid from 20:707 stigmasterol from 20:707 sitosterol from 20:707 ursolic acid from 20:707 Salvia heldreichiana 20:690,711 7-oxo- 13-epi-pimara-8,15-diene18-oic acid from 20:690 7p-hydroxy sandracopimaric acid from 20:690 di (4,4'-hexyloxy-carbonylphenyl) ether from 20:709 heldrichinic acid from 20:670
isopimaric acid from 20:690 salvigenin from 20:711 Salvia hierosolymitana 20:672 forskalinone from 20:672 Salvia leucophylla 20:4 Salvia limabata 20:673,683,702,712 abieta-8,11,13-triene from 20:673 ~-amyrin from 20:702 dehydrosalvilimbinol from 20:683 eupatilin from 20:712 ferruginol from 20:673 12-hydroxysapriparaquinone from 20:683 3,12-hydroxysapriparaquinone from 20:683 2-hydroxysaprorthoquinone from 20:683 limbinol from 20:683 luteolin from 20:712 manool from 20:691 pectolinarigenin from 20:712 quercetin-3-methyl ether from 20:712 salvilimbinol from 20:683 stigmasterol from 20:702 vergatic acid from 20:702 Salvia miltiorrhiza 2:402,26:235,29:212 cell suspension cultures of 2:402 danshensuan B from 26:235 Salvia montbretii 20:666,678,712,704 c~-amyrin from 20:704 apigenin from 20:712 7,7'-bistaxodione from 20:678 cirsitiol from 20:712 3 ~3-O-trans-p-coumro ylmonogynol A from 20:704 3 ~-O-trans-cis-coumaroylmonogynol A from 20:704 11,11 '-didehydroxy-7,7'-dihydroxytaxodione from 20:678 demethyleryptoj aponol from 20:666 ferruginol from 20:666 ferruginyl 12-methyl ether from 20:666 hypargenin F from 20:666
708 6-hydroxy-salvinolone from 20:666 7-hydroxy-axodione from 20:666 14-hydroxyferruginol from 20:666 luteolin from 20:712 lupeol from 20:704 monogynol A from 20:704 oleanolic acid from 20:704 salvinolone from 20:666 salvinolonyl- 12-methyl ether from 20:666 ~-sitosterol from 20:704 taxodione from 20:666 ursolic acid from 20:704 Salvia multicaulis 20:676,690 7[3-hydroxy-3,11-dioxo-pimara8(14),15-diene from 20:690 horminone from 20:673 12-methyl-5-dehydrohorminone from 20:676 12-methyl-5-dehydroacetylthorminone 20:676 1-oxoferruginol from 20:673 3-oxoferruginol from 20:673 18-oxoferruginol from 20:673 pisiferal from 20:673 sempervirol from 20:673 salvipimarone from 20:690 Salvia napifolia 20:670 acetyl-horminone from 20:670 cryptanol from 20:670 cryptojaponol from 20:670
11,12-dioxoabieta-8,13-diene
from 20:670 7,20-epoxyroyleanone from 20:670 ferruginol from 20:670 horminone from 20:670 1-oxoferruginol from 20:670 6-oxoferruginol from 20:670 pachystazone from 20:670 sugiol from 20:670 6,12,14-trihydroxyabieta6,8,11,13-tetraene from 20:670 Salvia nemorosa 20:669,702,712; 22:531
apigenin from 20:712 c~-amyrin from 20:702 2(x, 14-dihydroxydehydroabietic acid from 20:669 eupatilin from 20:712 luteolin from 20:712 24-methylenecycloartenol from 20:702 nemorosine from 20:669 oleanolic acid from 20:702 salvipisone from 20:683 salvinemoral from 20:702 [3-sitosterol from 20:702 stigmast-7-en-3-one from 20:702 stigmast-4-ene-3-one from 20:702 stigmast-7-en-3-ol from 20:702 ursolic acid from 20:702 Salvia officinalis L. 7:119;11:220; 25:128;26:402;27:376,377 ;28:391; 30:219 antimicrobial activity of 26:402 essential oils from 28:391 Salvia pinnata 30:244 apigenin from 30:244 luteolin from 30:244 Salvia plebeia 30:247 hispidulin 7-glucuronide from 30:247 Salvia pomifera 20:663,702,705 (z-amyrin from 20:702 erithrodiol from 20:705 ferruginyl 12-methyl ether from 20:663 23-hydroxygermanicone from 20:705 18-hydroxyabieta-8,11,13-triene7-one from 20:663 lupeol from 20:702 moradiol from 20:705 moronic acid from 20:705 pomiferin A-G from 20:663 [3-sitosterol from 20:702 taraxasterol from 20:702 Salvia potentillifolia 20:660 Salvia prionitis 5:31,33,36 Salvia sclarea 7:101,103,110,123; 20:633,660,669,691,712;22:531;
709 25:246,253 ;26:391-395,397,398, 400-406,412,413,415-419;27:376, 377 sclareol from 7:121 antimicrobial activity of 26:401 Salvia serotina 28:400 Salvia sp. 21:599 biological investigations of 20:659 chemical investigations of 20:659 Salvia splendens 5:646 Salvia tchihatcheffii 20:676,707 3-acetylerythrodiol from 20:707 28-acetylerythrodiol from 20:707 3-acetyloleanolic aldehyde from 20:707 313-acetylolean- 12-en-28-al from 20:707 salvitchitatine from 20:676 tchitatine from 20:676 Salvia tomentosa 20:9,667 ferruginol from 20:667 horminone from 20:667 1-oxo-abieta-8,11,13-triene- 18oic acid from 20:9 Salvia triloba 20:711;29:588;30:243 salvigenin from 20:711;30:243 Salvia uliginosa 30:247 petals of 30:247 Salvia wiedemanni 20:688,711 7[3-hydroxysandracopimaric acid from 20:688 isopimaric acid from 20:688 14-oxoisopimaric acid from 20:688 salvigenin from 20:711 Salvia yosgadensis 20:692,712 ambrenolide from 20:692 apigenin-7-methyl ether from 20:712 apigenin-4-methyl ether from 20:712 apigenin-7,4-dimethyl ether from 20:712 apigenin-6,4-dimethyl ether from 20:712 apigenin from 20:712
6c~,14-dihydroxymanoyl oxide15,17-diene- 16,19-olide from 20:697 6~x,16-dihydroxymanoyl oxide14,17-diene- 16,19-olide from 20:697 6(x-hydroxyambrenolide from 20:692 6(x-hydroxynorambrenolide from 20:692 6or -hydroxy-8(x-acetoxy- 13,14, 15,16-tetranorlabdane- 12-oic acid 20:692 kaempferol-3-methyl ether from 20:712 luteolin from 20:712 norlabdane diterpenoids from 20:692 norambrenolide from 20:692 yosgadensonol from 20:696 13-epi-yosgadensonol from 20:696 yosgandensolide A and B from 20:696 Salvianolic acids 30:221 synthesis of 30:221 Salvigenin 20:711;30:726 from Salvia triloba 20:711 from Salvia heldrichiana 20:711 from Salvia wiedemannii 20:711 structure of 30:726 Salvilimbinol 20:683 from Salvia limbata 20:683 Salvinemorol 20:702 from Salvia nernorosa 20:702 Salvinine 20:660 from Salvia divaricata 20:660 Salvinolone 5:34;20:666 APT spectrum of 5:34 ~3C-NMR spectrum of 5:33,34 CSCM 1D spectrum of 5:34 from Salvia montbretii 20:666 ~H-NMR spectrum of 5:33,34 INEPT spectrum of 5:34,35 Salvinolonyl-12-methyl ether 20:666 from Salvia montbretii 20:666 Salvipimarone 20:714 from Salvia multicaulis 20:690
710 Salvipisone 20:680 from Salvia candidissima 20:680 from Salvia nemorosa 20:683 Salvitchitatine 20:676 from Salvia tchihatcheffii 20:676 Salvitin 7:206-228 SAM (S-adenosylmethionine) 9:597, 601,603,604 ;23:21,29,34,41 SAM biomethylation 316 SAM MM 23:38 structure elucidation of 23:39 SAM MM1 23:29,41 ~3C-NMR assignments of 23:31 ~H-NMR assignments of 23:29 Samaderine-B 23:299 Samaderine-C 23:299 Samaderine-E 23:299 Samandarine 21:73 Samarium iodide mediated cyclization 8:232 Sambucinic acid 6:213,214,252;9:211 Sambucinol 6:213,214,246;9:207,210215,216 biosynthesis of 6:249,250 Sambucoin 6:213,214,237,247, 249;9:211 Sambucoinol 6:247 from sambucoin 6:247 Sambucus nigra 28:424;29:609;30:407 antiviral activity of 30:407 SAMM 23:26 SAMM 2 23:30,33,35,36 ~3C-NMR assignments of 23:31 chemical degradation of 23:30 crystallization of 23:33 ~H-NMR assignments of 23:29 HMBC spectrum of 23:28 hydrolysis of 23:32 mass spectra of 23:35 mechanism of 23:35 N-acetylation of 23:36 salt formation of 23:33 structure elucidation of 23:26 structure of 23:30 tautomeric structure of 23:36 tautomerism in 23:36 SAMM1 23:29,34,35,36,41 13C-NMR assignments of 23:31 ~H-NMR assignments of 23:29
structure elucidation of 23:34 tautomeric structure of 23:37 tautomerism in 23:36 Sampangine mammalian metabolite (SAM MM) 23:38 Sampangine-[3-glucopyranoside 23:3,25,30 Sampangine-[3-glucuronic acid (SAM MM1) 23:25 Sampangine-4'-O-methyl-[3-glucopyranoside (SAMM1) 23:3 13C-NMR assignments of 23:31 ~H-NMR assignments of 23:29 structure elucidation of 23:34 tautomeric structure of 23:37 tautomerism in 23:36 Sampangine-6-oxide 23:7 Sample preservation 21:501 Sampsoniones 30:625 structure of 30:625 (+)-Sanadaol 6:70,71 by intramolecular Michael addition 6:70,71 from bicyclo [2.2.2] octane derivative 6:70,71 synthesis of 6:70-72 Sanadaol ([3-crenutal) 6:71 from Dictyota crenulata 6:70 from Pachydictyon coriaceum 6:70 Sandalwood 20:730,774 Sandfly fever sicilian virus (SFSV) 30:410,412 phlebovirus type of 30:410 Sandosaponin A and B 21:659 Sandrasin A 23:624,625 ~3C-NMR data of 23:625 ~H-NMR data of 23:625 Sandrasin B 23:624,625 ~3C-NMR data of 23:625 ~H-NMR data of 23:625 Sandrosaponin I-X 27:678 sulfate olefaction of 27:678 Sang-Bai-Pi 28:209 as herbal medicine 28:209 Sanggenol C 28:230 biological activity of 28:230
711 Sanggenol M 28:230 biological activity of 28:230 Sanggenon A 28:212,230 biological activity of 28:212,230 from moraceous plants 28:201 Sanggenon B 28:230 biological activity of 28:230 from moraceous plants 28:210 Sanggenon C 28:212,230 biological activity of 28:230 from moraceous plants 28:201 Sanggenon D 28:212 biological activity of 28:212 from moraceous plants 28:210 Sanggenon M 28:230 biological activity of 28:230 Sanggenon O 28:201 from moraceous plants 28:201 Sanginarine 22:27 Sanguanella 23:656 Sanguidimerine 27:138,169 structure of 27:169 Sanguilutine 14:777,778,780,781; 27:172 free bases of 27:177 pK constant of 27:172 protoberberines 14:777,778 synthesis of 14:777,778,780,781 Sanguinaria canadensis L. 27:155,158, 159,162,169 Sanguinarine 5:42-46;14:770,771; 793-795;27:158,164,172,173,177, 178;21:68,80,89,96,97,102,108,109; 22:16,26,29,32;25:541;26:488 APT spectrum of 5:45 biological activities of 27:178, 179 biosynthesis of 14:770,771 13C-NMR spectrum of 5:45 CSCM 1D spectrum of 5:46 derivatives of 27:172,173 from coptisine 14:793-795 1H-NMR spectrum of 5:42 INEPT spectrum of 5:45 pK constant of 27:172 spectrum of 5:46 synthesis of 14:793-795 through cationic cyclization 14:793-795
Sanguirubine 14:770;27:156-158,159, 172 chelirubine 27:156-158,161,162 pK constant of 27:172 Sanguisorba officinalis 17:421,423; 23:397 polyphenols from 17:423 Sanguiwarine 13:662 Sanicula 29:581,582 Saniculoideae 27:661 7-Sanshool 10:152;21:378,380 Sanshool 26:450 [3-Santalene 4:607,608 asymmetric Diels-Alder reaction 4:607,608 (+)-c~-Santalene 4:674;16:136 (+)-epi-~-Santalene 4:675 (+)-[3-Santalene 4:675 (-)-[3-Santalene 8:145-148;16:136 synthesis of 8:145 c~,~-Santalol 29:91 activity in skin-1, ODC assay systems 29:91 from sandalwood oil 29:91 (+)-c~-Santalol 4:674;16:128 (+)-~-Santalol 4:674;8:145-148;16:128 synthesis of 8:145 (-)-Z-[3-Santalol 8:145 synthesis of 8:145 (-)-E-[3-Santalol 8:145-147 synthesis of 8:145 [3-Santalol 8:145 from Santalum album 8:145 Santalum album 8:145 [3-santalol from 8:145 Santamarin 7:232;27:555 Santin 7:228 (-)-ot-Santionin 6:11,12,548;20:760 guaianolide from 6:548 (• from 6:11,12 Santonia chamaecyparissus 7:100, 101;29:88 Santonin 13:660 fromArtemisia maritima 13:660 (l)-c~-Santonin 14:406-413 synthesis of 14:406-413 (-)-c~-Santonin 14:464;24:53-125 eudesmane alcohol from 14:464
712 photochemical rearrangement of 14:357-360 [3-Santonin 2:163 6-epi-Santonin 24:123 Santonin 26:462,463,466,477,478 c~-Santonin 7:212,232;29:88 activity in CRG assay system 29:88 6-epi-ct-Santonin 6:27 (-)-dictyolene from 6:27 ~-Santonin 7:212,213 Sapargine 25:528 as immunosuppressive drug 25:528 Sapindaceae 7:427 Sapindoside B 21:656 Sapindus emarginatus L. 22:531 for epileptic fits 22:531 Sapindus mukurossi Gaertn 22:531;27:21 Sapindus rarak DC 21:660;27:13 mukurozioside from 27:13 Sapindus trifoliatus L. 22:531 for epilepsy, hysteria and hysteroepilepsy 22:531 Sapintoxin 7:188,189 Sapium 25:242 Sapium genera 27:830 Sapium indicum 7:188 4a-sapinine from 7:187 SAPO 50 26:41 hemolytic activity of 26:41 Sapogenin 1:305;9:51,61,73;18:649,650 Sapogenol 7:139,156,157,270,286; 24:132;25:89,94,116 Saponaria 26:55 of adjuvant activity 26:55 Saponaria officinalis 24:131,144,149, 155,161 ;26:3,4,5,6,10,13,15,17,18, 20,27,30,42,54,57 ;30:407 antiinflammatory activity of 26:27 antiviral activity of 30:407 gypsogenic acid from 26:5,6,18 gyspogenin from 26:5,6,18 3 [3-hydroxy-oleana-11,13(18)dien-23,28-dioic acid from 26:5,6
saponariosides C-M from 26:10,12,13,17,18 saponaside A from 26:17,2023,423,4-secogypsogenic acid from 26:5,6 triterpenoid saponins from 26:17,20 Saponarioside C 26:26 HMBC correlations of 26:15,25 HOHAHA spectrum of 26:10 MALDI-TOF MS of 26:26 phase-sensitive NOESY spectrum of 26:12 Saponification 6:146,162,445,447; 19:322 Saponin avenacin A-1 25:320 Saponin Bb 21:664 Saponin C2 27:41,45,46 structure of 27:46 Saponin E 27:41,45,47 structure of 27:47 Saponin fraction 30:86 in oolong tea 30:86 Saponin glycosides 23:343 Saponin H 27:41,45,47 structure of 27:47 Saponin QS-21 21:646 Saponinase 25:312 4ot-Saponine 7:187 from Sapium indicum 7:187 Saponins 1:305;9:50-64,402;7:155,156, 190,426-432,434,435 ;18:649,650; 23:497;24:131,215,241 ;27:446,671 from Caralluma tuberculata 9:62-64 from Guaiacum officinale 9:5059 from Symphytum officinale 9:6062 from Zygophyllum propinquum 9:59-62 molluscicidal activity of 7:427,428 ofcycloartane series 27:446 ofquillaic acid 7:155,156 oligosaccharidic moiety of 27:524,673 sulfate olefaction of 27:678
713 structure elucidation of 15:187224 Saposhnikovia divaricata 27:422; 29:682 Saposhnikoviae radix 27:422 Saprolegnia parasitica 9:577,578 Saprophyton glaucum 9:37 papkusterol (glaucasterol) from 9:37 Saprorthoquinone 5:36 Saquayamycnis 24:480 FPTase inhibition by 24:480 Saquinavir 24:489 inhibitor of HIV- 1 protease 24:489 SAR 26:167,168;30:205 of (+)-allomatrine 30:205 of (+)-matrine 30:205 of podophyllotoxins 26:167,168 Sarain A 21:308 Saraine (cyclostellamine) 24:573,650, 651,660-662 Sarasinoside A~ 192 Sarcina lutea 12:401;23:199 Sarcinaxanthin 7:355-357;20:597 Sarcoaidesterols A & B 25:704 Sarcocapnos enneaphylla 3:428
Sarcodon leucopus (Sarcodon laevigatus) 29:278 M5076-Sarcoma 19:289 Sarcoma-180 26:303
Sarcomelicope agyrophylla 20:807 Sarcomelicope simplieifolia 20:807 Sarcomelicope dogniensis 20:806 Sarcomelicope glauce 20:806 Sarcophaga bioassay 29:25 ajugasterone C activity in 29:28 amarasterone A activity in 29:28 amarasterone B activity in 29:28 cyasterone activity in 29:28 ponasterone A 2~-glucoside activity in 29:28 pterosterone activity in 29:28 rubrosterone activity in 29:28 sengosterone activity in 29:28 stachysterone C activity in 29:28 capitasterone activity in 29:28 Sarcophine 21:280
Sarcophytol A 10:4,5;21:279,281; 29:100 activity in EBV assay system 29:100 activity in colon-2 assay system 29:100 activity in liver-2 assay system 29:100 activity in lung-1 assay system 29:100 actwity in mam-3 assay system 29:100 actwity in pancr assay system 29:100 actwity in skin-2 assay system 29:100 Sarcophytol B 8:18;29:100 activity in skin-2 assay system 29:100 activity in mam-3assay system 29:100 antileukemic activity 8:18 carbonyl coupling 8:18,19 synthesis of 8:18,19 Sarcophyton glaucum 8:18;21:279 Sarcophytum sp. 25:704 Sarcoptes mites 28:410,416 cause of human scabies 28:410 symptoms of 28:410 Sarcoptes scabiei 28:409,416 cause of mange mites 28:409 cause of scabies 28:409 Sarcosine 1:335,336;25:537 decarboxylation of 1:335,336 Sarett oxidation 14:635 Sarett reagent 4:434;6:27,28 Sargasm horneri 30:400,405 anti-CMV activity of 30:405 polysaccharide (PS) from 30:400 Sargassum lacerifolium 25:867 Sargassum muticum 26:1152 Sargassum tortile 20:25-27,29,34-36 Sargasum muticum 30:400 polysaccharide (PS) from 30:400 Sargramostim 13:661 Saringosterol (24-hydroperoxy-24-vinylcholesterol)10:249 Sarisan 7:415
714 Sarkomycin 3:44;8:150 as antitumor agent 8:150 synthesis of 3:44;8:150 Sarmentine 21:378,384,386 Sarmentosin 21:737,738,739,740 synthesis of 21:739,740 Sarothalen B 26:797 Sarotherodon nilotica 7:184 Sarothra gentianoides 30:605 n-nonane from 30:605 Sarpagine 13:384-386,403,427,429 Sarpagine-type indole alkaloids 15:466471 Sarracenin 3:239;7:442 synthesis of 3:44,243 Sassafras sp. 21:596 Sativene 17:608 (-)-Sativene 4:675 (+)-cis-Sativenediol 16:265 Satratoxins 30:743 antiviral activity of 30:743 Saucy-Marbet rearrangement 10:417 Saururus cernuus 17:319 Saussurea lactone 7:216,237 Saussurea lappa 22:531 ;29:89,90 for epilepsy 22:531 Savinin 13:653;26:231 as cytotoxic agent 13:653 Saxicola insignis 5:837 hemoglobin components of 5:837 Saxidomus gigantius 5:3 Saxifragifolins A and B 15:200 from Androsce saxifragiifolia 15:200 Saxitoxin 5:403;17:3;18:697,698;21:73; 25:684,730 synthesis of 1:342 Sayasaponin I 25:120 Scaberoside B5 15:211 Scaevola racemigera 6:522 strychnovoline from 6:522 12-epi-Scalaradial 6:111 from Dictyoceratidae 6:58 Scalaradial 6:111 ;25:695,696 from Dictyoceratidae 6:58 Scalarane 6:111,123 Scalarane ring system 6:58
(+)-Scalarane-type sesterterpenes 6:122-129 synthesis of 6:122-129 Scalardysin 25:697,900 Scalarene-type sesterterpenes 6:107-132 stereoselective synthesis of 6:107-132 12-epi-Scalarin 17:10 Scandenoside R11 27:15,25,26,27 structure of 27:27 Scandenoside R6 27:15,25,26 structure of 27:26 Scanning electron microphotographs 27:399 structure of 27:399 Scanning electron microscopy (SEM) 23:335,380 Scapaniapyrone A 9:95 O2-Scavenging acitivity 22:314,345 Scavenging activity 21:675;26:204 ofKrameria triandra 26:204 Scavenging effects 23:443 of tannic acid 23:443 Sceletium alkaloid A4 1:333 synthesis of 1:333 Scenedesmus obliquus 26:373 Sceptrin 25:779 SCH 207278 24:451 FPTase inhibition by 24:451 Schaefferia cuneifolia 18:761 Schaffer collateral 25:959 Schefflera sp. 27:686 Schelhammera spp. 3:455,483 epi-Schelharnrnericine 3:483,484 epi-Schelhamrneridine 3:486,456 synthesis of 3:486,456 Schelhammmera pedunculata 3:484,486 Schelhammmericine 3:501,484 Schiff base 14:175,16:397,401 Schiff formation 19:42 Schiff's base mechanisms 20:833 Schilrs synthesis 14:861,862 of vinblastine 14:861,862 Schima walichii 23:405 Schimawalin B 23:405 Schinus terebinthifolius 22:131 Schisandra 26:183 decrease of heart rate 26:183 effect on cardiovascular system
715
26:183 effect on heart rate 26:183 for treatment of hepatitis 26:183 platelet activating factor antagonist activity in 26:183 Schisandra chinensis 26:203,204,244, 247,249-251,255,258,265 chamigrenal from 26:244 gomisin N from 26:249 pregomisin from 26:244 schisandrin A from 26:203,244 schisandrol A from 26:203 schisandrol B from 26:203 schisandrin C from 26:203 Schisandra rubriflora 26:205 Schisandrin 26:238,270 Schisandrin A 26:197,244 Schisandrin C 26:224 Schisandrol A 26:245 as PAF-induced inhibitor 26:245 Schisanhenol 26:250,251 Schisantherin D 26:197,223,224, 247,256 Schistocerca 9:498 Schistocerca gregaria 24:715,716; 26:700;29:6 Schistochila appendiculata 2:280281 Schistosoma haematobium 7:425 Schistosomajaponicum 7:425;23:138 Schistosoma mansoni 7:425,428;23:138 Schistosomiasis (Bilharzia) 7:405,408, 425,426,435 Schistosomicidal activity 1:545 (-)-Schizandrin 20:412 Schizandrin 26:197 Schizandrin B 5:461,462 S-(-)-Schizandrin C&D 26:250 Schizaphis graminum 23:535 Schizolobium parahybum 29:605 Schizonepeta tenuifolia 26:251,252 schizotenuin A from 26:251,252 schizotenuin C~ from 26:251,252 schizotenuin C2 from 26:251,252 Schizonticidal drug 26:837 Schizophrenia 21:101 ;25:531 ;30:368, 369,379 effect of circadian activity on 30:369 Schizophyllan 5:321 ;23:115,123
Schizophyllan triple helix 23:120 Schizophyllum commune 1:680,681; 8:352;5:288,316;18:460,813,814; 23:111,115;25:452 cellulase from 8:352 fruiting body formation of 1:680,681 Schizosaccharomyces octosoporus 5:280,286,293 Schizosaccharomyces pombe 5:280,286;12:398;18:721 ;26:1093,10 97,1098,1128 Schizotenuin A 26:251 Schizotenuin C1 & C2 26:251 Schizothrix calcicola 18:294,20:586 Schlerochiton ilicifolius A 15:335; 27:18,38 monatin from 27:18 Schlessinger 29:370,384 steganes synthesis by 29:370,384 Schlosser-Wittig reaction 16:482 Schmidt reaction 16:472 intramolecular 16:472 Schmidt rearrangement 13:95;16:472; 29:365 in allocolchicinoid synthesis 29:365 Schoberidine (dihydronitrarine) 1:125, 126;14:759 biosynthesis of 14:760 Schoberine 14:758 biosynthesis of 14:758 from Nitraria schoberi 14:757 X-ray analysis of 14:757 Schoellkopf reagent 10:653,655 chiral induction with 10:653, 655 Schollkopf system 4:125 Schollkopfs isocyanides 10:88 c~-metalated 10:88 Schotten-Baumann acylation 10:131 with 2,2,3-trimethylethanolamine 10:131 Schotten-Baumann reaction 11:448 Schottenol glucoside 30:720 structure of 30:720 Schreiber's synthesis 30:6-10 of (+)-discodermolide 30:6 Schumannificine 21:142-145,148-150
716
Schumanniophyton magnificum 21:139,140 Schumanniophyton sp. 21:124,125, 144,153 Schumanniphytine 21:145,147 Schwann's cells 22:586 Schwanniomyces alluvius 5:283 Schwanniomyces castelli 5:283 Schwartz's reagent 21:381 Schweinfurthia papilionaceae 9:75, 76,78 alkaloids from 9:75,76,78 Schweinine 9:75,76,78 Sciadopitys verticillata 20:107; 23:489,493 Scilla maritima 25:535 Scillarenin 3-O-glusyl rhanmoside 25:535 Scilloideae 21:644 [3-Scission 23:768 Scitonemin A 5:429 13-epi -Sclareol 25:246 Sclareol 7:100,101,103,110,122-123; 26:394,402 from Nicotiana glutinosa 7:121 from Salvia sclarea 7:121; 20:691 Sclareol glycol 25:265 Sclareol isomers 25:266 Sclareolide 25:253;26:394 7a-hydroxy derivative 25:253 Scleritoderma 25:703 Scleritoderma sp. 26:1215 Scleroglucan 5:279,314;23:115 antitumor activity of 5:317 Sclerosporal 6:546 synthesis of 6:549-551 Sclerosporene 6:546 Sclerosporin 6:549-551 absolute configuration of 6:549551 from Sclerotiniafructicola 6:546 structure elucidation of 6:546549 synthesis of 6:546-551 (+)-Sclerosporin 6:549-551 from (-)-carvone 6:549-551 Sclerotinia 4:246
Sclerotinia cinera 12:401 Sclerotinia fructicola 6:546,547 sclerosporin from 6:546 Sclerotinia sclerotiorum 15:385;18:269; 21:197,209;23:125;26:405,418; 28:123 Sclerotinin A and B 15:385 Sclerotium cerevisiae 5:279-282, 285,323 Sclerotium fermenti 5:280 Sclerotium fragilis 5:280,282 Sclerotium glucani 5:277 Sclerotium glucanicum 5:314; 23:115,142;30:401 scleroglucan from 30:401 Sclerotium libertiana 5:277 Sclerotium rolfsii 5:314;21:234,235; 23:142;26:405,418 Sclerotium rouxii 5:282 Scolytus multistriatis (elm-bark beetle) 15:348;19:127 Scolytus scolytus 15:348,349 Scopadiol 21:690 Scopadulan- type diterpenoids 21:692, 721 biosynthesis of 21:721-723 structure activity relationship of 21:717 synthesis of 21:706-717 Scopadulciol 21:691 Scopaduleic acid A and B 21:690 Scopadulin 21:690 Scopaliajaponica 22:531 Scoparia dulcis 21:689,690,692,704, 722,723 ;25:263 ;27:193 ;29:101 Scoparic acid A,B and C 21:690;25:263 Scoparinol 29:101 activity in CRG bioassay system 29:101 from Scoparia dulcis 29:101 Scopariosides A-D 15:68 Scoparone 5:515,516;22:532,541; 26:315,332-334,342 Scopine 16:442;22:731 synthesis of 16:442 Scopodrimol 7:224 Scopofarnol 7:204,205,224 L-Scopolamine 21:104
717 Scopolamine 5:515,520,521 ;13:662; 21:98,56,488;22:730,731 antichlolinergic agent 17:395 from Hyoscyamus niger 13:631 from phenylalanine 11:204,206 Scopoletin 5:515,520;7:117,120,204, 205,224 ;22:532,541 ;23:342,354,356, 536,550;26:315,333,666 analgesic activity of 5:521 hypertensive activity of 5:521 Scopolia genus 17:395 Scopoliajaponica Maxim. 5:505; 22:742,532 atropine from 5:505;22:742 for convulsions 22:532 Scopolia sp. 21:104 Scopolin 5:515,516;7:204,205,224 Scorbethane 4:725 Scorpiurus muricatus 19:117 Scoulerine 11:204,205 aromatization of 11:204,205 by S-tetrahydroprotoberberine oxidase 11:204 to dehydroscoulerine 11:204,205 SCR gene expression 25:387 Scripus maritimus 9:391 Scrophularia auriculate 29:84 Scrophularia canina 7:476 Scrophularia scorodonia L 29:685 Scropolioside A 29:84 activity in TPA assay system 29:84 Scrovalentinoside 29:84 activity in TPA assay system 29:84 Sculponeatin A 15:141 13C-NMR of 15:158 from Rabdosia sculponeata 15:174 ~H-NMR of 15:150 Sculponeatin B 15:142 13C-NMR of 15:159 from Rabdosia sculponeata 15:174 ~H-NMR of 15:151 Sculponeatin C 15:141 13C-NMR of 15:158 from Rabdosia sculponeata
15:174 1H-NMR of 15:150 Sculponeatin D 15:144 13C-NMR of 15:161 from Rabdosia sculponeata 15:174 1H-NMR of 15:153 Scutellarein 21:690;30:288 structure of 30:288 Scutellaria altissima 30:250 baicalein from 30:250 Scutellaria baicalensis 24:219-228; 27:431 ;29:678;30:55,56,69,254,289 baicalein from 30:55 flavonoids from 30:56,289 in allergric inflammatory disease 30:69 viscidulin III from 30:254 Scutellaria discolor 30:251 norwogonin from 30:251 wogonin from 30:251 Scutellaria galericulata L. 22:532 for epilepsy 22:532 Scutellaria lateriflora L. 29:678 Scutellaria ocellata 30:248 wogonin from 30:248 Scutellaria orthocalyx 29:679 Scutellaria przewalskii 30:249 apigenin from 30:249 Scutellaria spp. 29:581 Scutellaria tenax 5:678 Scutellariae radix 27:431 biological activity of 27:431 Scutionin (xB 30:685 13C-NMR spectra of 30:685 2D NMR spectroscopic data of 30:685 ~H-NMR spectra of 30:685 molecular formula of 30:685 structure of 30:685 Scyllo-inositol 7:37,38 from c~-glucosidases 7:37,38 Scyllo-nitrocyclitols 7:157 Scylonema hofmanni 26:363 Scyphyphora hydrophyllaceae 7:176 Scytatidlin 22:73 Scytonema mirabile 28:144 Scytonema sp. 5:429
718 SDB 21:695 inhibitory effect of 21:695 SDC 21:695 inhibitory effect of 21:695 SDS buffers 25:338 SDS denaturation 25:333 SDS micelles 18:832 SDS PAGE gels 25:370 SDS-electrophoresis 7:284 SDZ-249-665 30:201 antinociceptive activity of 30:201 anti-hyperalgesic activity of 30:201 77Se 9:109-122 natural abundance of 9:110 respectivity of 9:110 resonance frequency of 9:110 spin quantum number of 9:110 SE Additions 10:17-25 Sea cucumbers 28:597 calcigeroside C2 from 28:597 calcigeroside D2 from 28:597 cucumarioside A0-1 from 28:597 cucumechinoside A from 28:597 cucumechinoside B from 28:597 cucumechinoside C from 28:597 cucumechinoside D from 28:597 cucumechinoside E from 28:597 cucumechinoside F from 28:597 triterpene glucosides from 28:601 Seasonal affective disorder 30:369 effect of circadian activity on 30:369 Seaweeds 30:404 anti-CMV activity of 30:404 SEB staphylococcal enterotoxin B 25:465 Secale cereale L. 18:500,502,512; 19:247;27:125,188,191,193,216,217; 29:613 allelopathic interaction of 27:125,216 Secalonic acid 27:849 13,14-Seco- 13,14-dioxoabiet- 13-en- 18oic acid 29:100 activity in EBV assay system 29:100
6,7-Seco- 19,20-epoxyangustilobine 9:178 6,7-Seco-6-cyanostemmadenine 9:178 9,10-Secoabieta-8,11,13- trien- 18,10olide 13:70 Seco-acid 12:52,53 lactonization of 12:52,53 via-2-pyridine thiol ester 12:52,53 Secoadociaquinones A and B 25:861 Seco-ajmalicine 14:563,564 Seco-analogues 15:229 6,7-Secoangustilobine A,B 9:178 2,3-Secoaromadendrane sesquiterpenoids 2:280 (-)-5-Nor-4,5-Secoartemisinin 22:161 Secodehydroabietane 10:407 from pine tall oil 14:642 synthesis of 14:642 Secodeoxybouvardin 10:640-642 D-Secodesethylcleavamine 4:33 vinblastine analogues from 4:33 D-Secodesethylvincadifformine 4:33 synthesis of 4:33 Secodines 4:39-41 Secodine-type alkaloid 5:110 decarbomethoxy- 15,20,16,17tetrahydrosecodine 5:110 9(11)-Secodinosterol 21:312,313 Secodolastane 9:79 1,2-Secoemetine derivatives 6:485 amoebicidal activity of 6:485 synthesis of 6:485 9(11)-Secogorgosterol 21:312 Secogorgosterols 23:166 3,4-Secogypsogenic acid 26:29 Secoiridoid glycosides 25:471 Secoiridoids (isoprenoids) 7:185,442, 443;13:67;16:289;26:330 antimicrobial activity of 26:330 gentiopicroside type 7:443 oleuropein type 7:443 secologanin type 7:443 Secoisolariciresinol 20:108; 26:204,205,206 (-)-Secoisolariciresinol 26:156,157, 186,188,191 (-)-Secoisolariciresinol diglucoside 26:191
719 Secoisolariciresinol diglycoside 26:248 (+)-Secoisolariciresinol di-p-coumarate 20:620 Secolactam 25:33 Seco-lanostane triterpenes 22:105 Secologanin 1:31,32;7:442,477,478; 13:662;15:487 ;20:47 ;26:95-98,100, 105,110,111,114-118,127,132,137, 138,140,143,144 chemical transformation of 26:97,99 coupling reactions of 26:113, 114,119 from Lonicera morrowii A. Gray 16:307 tryptamine condensation with 6:520 Secomanoalide 18:717 "Second generation" synthesis 12:269 ofphorbol 12:269 Second messenger 25:516 Secondary allylic ethers 3:249 [2,3]-Wittig rearrangment of 3:249 Secondary hydroxyl protection 1:312,313 as tert-butyldimethylsilyl ether 1:312,313 Secondary isotope effects 9:572 Secondary metabolism 7:93,98,110,112, 114,119,120 Secondary metabolites 15:226,227; 18:677-728;23:592;28:3,432,617 acaricidal activity of 28:432 biological activity of 28:617 biosynthesis of 20:291-293 chemistry of 23:592 evolution of 18:677-728 production of 2:369-415 sector rules 2:165 Secondary metastatic tumor growth 30:64 effect of triterpenoids on 30:64 Secophenanthoindolizidine alkaloid 27:517 Seco-polyol 12:48,49 Seco-pseudoaspidospermane skeleton 19:104 Seco-pseudopterosins 23:158
2,3-Secoreserpine 25:12,33 3,4-Secoreserpine 25:12,33 9(11)-Secosteroids 21:312,313 Secosterol 9:510 9,11-Secosterols 23:168 Seco-taxane 12:181,182,203 synthesis of 12:181,182,203 Secoxyloganic acid 26:100 Seco-yohimbine 14:566,567 yohimbine from 14:566,567 Secretory activity 21:98 Secretory fungal peroxidases 27:736 Securidoca longepedunculata 22:532 Securiflustra securifrons 18:691 Securinega alkaloids 5:49 Securinega sp. 10:153 Securinine 21:69;22:26 (-)-Securinine 25:528 Securinine alkaloids 14:657-659 via Norrish type II reaction 14:657-659 Securinol A 14:657 Securinol B 14:657 (+)-Sedacryptine 13:481 (-)-Sedamine 10:677;13:475,477 Sedative 22:513-514,599;27:660 arnica as 22:559 Artocarpus heterophyllus as 22:513 Basilicum polystachyon for 22:514 Sedative activity 21:673 Sedative in convulsions 22:518 Crocus sativus L. for 22:518 Sedative in epilepsy 22:535 Withania somnifera L. as 22:535 (+)-Sedridine 16:457 Sedum sarmentosum 21:737 Seed oil (Croton oil) 25:242 Segetalic acid 26:30 Segoline A 23:276 Selagin 7:228 Selaginella tamariscina 24:273 Selection 7:116,117 by autoxicity 7:116,117 of metabolically-active cells 7:114-117 Z-Selective 4:125 Wittig olefination of 4:125
720
Selective acylation 12:346;13:586; 14:163 ~t-Selective agonist 30:807 dermorphin 30:807 Selective aldehyde reduction 13:579 8-Selective antagonist 30:806,811 Tyr-Tic-Phe-NH2 30:806 Selective antitumor activity 15:355 Selective benzoylation 13:557;14:244 Selective cleavage 7:155 of bisdesmosides 7:155 of ester type glycoside linkage 7:154,155 of glucuronide linkage 7:156-158 of sugar aglycone linkage 7:154-158 Selective cytotoxicity 13:648 Selective deoxygenation 14:160 of maltose 14:160 of primary alcohol 16:348 Selective deprotection 12:345 [3-Selective glucosylation 15:28 Selective heteronuclear J-resolved spectroscopy 2:147 Selective hydrogenation 6:83 in (+)-9-isocyanopupukeanane synthesis of 6:83 with iridium black 6:83,85 Selective hydrolysis 12:343;13:571 2D Selective J-resolved spectra 2:115 Selective ketalization 6:33;24:175 Selective mesylation 12:326,335 Selective monotosylation 13:620 Selective O-methylation 12:485 5-Selective opioid agonist 30:817 deltorphin B 30:817 g-Selective opioid peptide 30:802 5-Selective opioid peptide 30:817 Selective reaction 6:282,283 acylation 6:282,283 esterification 6:276 formation of cis-5-oxo- 1indanones 6:558 hydrolysis 6:285,286 Selective redox reaction 20:817-881 chiral synthesis by 20:817-881
Selective reduction 14:145;24:9,10 of methyl 4,6-O-benzylidene-2,3di-O-tosyl-ot-D-glucopyranoside 14:145 Selective silylation 12:330;24:30-32 K-selectride 12:475 oftriol 4:184 Selective skeletal rearrangement 14:377 Selective synthesis 18:315-386 of 5-1actams 18:315-386 of pyridones 18:315-386 c~-Selective thermal glycosidation 8:367 of cyclooligosaccharide 8:367 of cyclo-L-rhamnohexaose 8:367 c~-Selective thermal rhamnosylation 15:28 Selective thiocarbonylation 14:162 of sucrose derivative 14:162 with thiocarbonyl diimidazole 14:162 syn-Selectivity 12:58 to (2R)-methyl aldehyde 12:58 K/g-Selectivity 30:811 of 6N-cinnamoyl- [3-naltrexamine (CNX) 30:811 of ICI 19944 30:811 ofk opioids 30:811 6,~t-Selectivity 30:819 in vivo 30:819 of glyco analogues 30:819 threo-Selectivity 4:130,145 in cyclocondensation 4:130,145 in N-protected alaninals 4:122 erythro-Selectivity 4:143 endo-Selectivity ( UL-addition) 6:549, 550;8:411,415-417 K-Selectride 14:179 anhydride reduction with 3:489 in stereoselective reduction 4:437,459 L-Selectride 16:454;19:72,419,478,494, 629 reduction with 4:470,516;6:38, 39;14:378,379;18:235 1,2,3-Selenadiazoles 9:121-123 77Se-NMR of 9:121-123 Selenastrum capricornutum 26:373,
721 374,377-379;29:329 Selenation oxidation 6:74,75 in (-)-pseudopterosin-A synthesis 6:74,75 Selenium dioxide 1:549,550;22:222 for allylic oxidation 1:549,550 Selenium dioxide oxidation 1:74 Selenium glycoside 10:382,383 c~- Selenoalkyllithiums 8:5,11 as key intermediates 8:3 c~-Selenobenzyllithiums 8:3,5,11 Selenocyclization 11:98,99,101,102 Selenoetherification 10:207;11:109 Seleno-lactonization 13:622,623 Selenoxide-based elimination 1:248 Selenylation 1:452;6:70 Self-incompatibility (SI) 25:402 Self-incompatibility in pollen 25:386,393 Self-inhibitors 9:230,231 bioassay of 9:230,231 biological activity of 9:222,237 (-)-Selin-11-en-4c~-ol 14:450,451 biological activity of 14:450,451 from Euginia uniflora 14:450,451 from Humulus lupulus 14:450 from Myrica gale 14:451 from Pisidium guajava 14:450 from Podocarpus dacrydiodes 14:449,450 from Riccardiajackii 14:450 synthesis of 14:456-465 Selin-11-en-4c~-ol 21:581 (-)-c~-Selinene 14:406-413 from tosylhydrazone 14:411 synthesis of 14:406-413 (+)-~-Selinene 16:214 (+)-a-Selinene 16:220 [3-Selinene 21:581;23:815 (+)-c~-Selinene 6:40 from cycloeudesmol 6:40 Selinum vaginatium 5:728 Selligueafeei Bory 15:33;27:18,35 selligueain A from 27:18,35 Selligueain A 15:33;27:18,35,36,37 structure of 27:36
Semecarpus anacardium L. 22:532 for epilepsy and hysteroepilepsy 22:532 Semecarpus heterophylla 9:319 Semecarpus vernicifera 9:319 Semi synthesis 29:363 of (-)-rhazinilams 29:363 Semibullavene 5:776 13C-NMR spectrum of 5:776 Semi-empirical methods (AMI) 22:568, 569,576;30:542 for calculations 30:542 Semilicoisoflavone B 28:229 biological activity of 28:229 Semiochemicals 6:537-566 chiral synthesis of 6:537-566 synthesis of 8:219-256 Semiquinolamine 26:1273 Semisynthetic LSD 26:820 as psychodelic drug 26:820 (+)-Semivioxanthin(9,10-dihydroxy-7methoxy-naphtho-[2,3,c] pyran- 1 (1H)-one) 11:130 antibiotic activity of 11:130 antifungal activity of 11:130 by polyketide methodology 11:130,131 from ~-oxoglutarate derivative 11:130,131 synthesis of 11:130,131 Sempervirine 15:466,467 synthesis of 1:136,140,141, 145,146,157 Sempervirol 20:673 fromSalvia acetobulosa 20:673 from Salvia multicaulis 20:673 Sendai virus infection 30:412 Senecio isatideus 21:305,306 Senecio 26:872 Senecio amplexicaulus 14:450 endesm- 11-en- 14-ols from 14:450 (+)-intermedeol from 14:450 Senecio erraticus 26:874 Senecio glaber 26:874 Senecio litura 26:851,853-855,858860,863-866 Senecio microphyllus 26:874
722 Senecio oxyodontus 13:13 senoxydene from 13:13 Senecio palmensis 26:859 Senecio toxicosis 7:23 6a-Senecioloxychaparin 7:380,381,396 Senecionine 22:35;26:876 6c~-Senecioyloxychaparrinone 7:380383,396 Senecivernic acid 1:264 Senercinine 1:203 synthesis of 1:203 Senescent plant 27:86 lipid peroxidation products of 27:86 sapogenins from 27:466 Senieramycin 25:826 77Se-NMR 9:119 of phenylselenyl alkanes 9:119 of phenylselenyl cyclohexane 9:119,120 of 1,2,3-selenadazoles 9:121-123 Senna multiglandulosa 22:580 Senna occidentalis 26:1143 Senna spp. 22:580;26:1139 Sennosides 30:305 structure of 30:305 Sennosides A,B,C and D 11:127 Senoxydene 3:6,8,62,118;13:14-20 from Senecio oxyodonius 13:13 synthesis of 3:10 Sensory neurons 30:194 hyperpolarisation of 30:194 Sentellaria scandens 30:253 5,7,2 ',5 '-tetrahydroxy- 6methoxyflavanone from 30:253 Separation scheme 27:507 of polysaccharide 27:507 Sepedonium ampullosporum 25:318 Sephadex G-200 chromatography 2:392,395,399 Sephadex LH-20 21:532;30:234 use for flavonoid purification 30:234 Sephadex LH-20 chromatography 30:502 Sepositoside A 15:59,60;7:295 from Echinaster sepositus 7:294 Separation method 27:507
Septicine 1:277,284,287,293,360,361 synthesis of 1:277,284,287,293, 360,361 (+)-Septicine 16:454 synthesis of 16:454 Septoria lycopersici 25:293,295,301, 302,304,307,308,314-316 Sepulchre's method 19:367 Seqarine 1:35 Sequencerules 5:774 Sequential Horner-Emmons condensation 13:608 Sequestration 17:93,104 Sequiterpenoids 27:855 Sequoia sempervirens 28:408 Ser264 inhibitors 26:368 Seratia marcescens 12:103 Serendipitous deconjugation 12:28 Sergeolide 7:381,382 Sergolide 26:815 Serial Michael additions 14:756 Sericea lespedeza 21:502,521 L-Serinal 4:122,127,130 and Danisefsky's- diene addition 4:130 in cyclocondensation 4:122 Serindea warneckei 23:342 Serine 11:420;27:850;30:836 activity of 27:850(z2macroglobulin inhibition by 30:836 synthesis of 11:420 L-Serine 4:130;21:218 L-alanine analogue of 4:127 pyrrolidine from 14:568 Serine protease inhibitor proteins 29:617 arrowhead PIs API-A & API-B as 29:617 Brassica BN as 29:618 Brassica TIBN as 29:618 Cassia defensin PI as 29:617 Cp-thionin as 29:617 effects on barley malt cysteine endoproteinases 29:617 effects on chymotrypsin 29:617 effects on subtilisin 29:618 effects on subtilisin (or-amylase inhibitors) 29:617
723
Eleusine double-headed TRY-c~amylase inhibitor I-2 as 29:617 from Brassica nigra 29:618 from Brassica napus 29:618 from Cassia fistula 29:617 from Eleusine coracana 29:617 from Hordeum vulgare 29:617 from Phaseolus angularis 29:617,618 from Sagittaria sagittifolia 29:617 from Sinapis arvensis 29:618 from Vigna unguiculata 29:617 Hordeum lipid transfer proteins as 29:617 Phaseolus Defensin PI as 29:617 Phaseolus LTP PI as 29:618 Serine proteases 25:388;29:570;30:70, 830,832,833,840 active site of 30:833 amino acid of 30:833 annelid worm from 30:832 binding groups of 30:833 blood clotting factors as 29:570 cathepsin G as 29:570 chymase as 29:570 chymotrypsin as 29:570 cleavage site of 30:833 cysteine proteinase inhibitor 25:370 EFEa as 30:840 F-I-2 as 30:840 F-II as 30:840 F-I-I as 30:840 granzymes as 29:570 in angiogenesis 29:570 m blood clotting 29:570 in cytosolic proteolysis 29:570 m digestion 29:570 in inflammation 29:570 m proprotein processing 29:570 m tissue remodelling 29:570 kallikrein as 29:570 plasmin as 29:570 poly phenol oxidase 25:370 prolyl endopeptidases as 29:570 role in blood coagulation 30:70 role in platelet activation 30:70 role in pulmonary vascular injury
30:70 serine proteinase inhibitor II 25:370 subtilisin as 29:570 thrombin as 29:570 trypsin as 29:570 tryptase as 29:570 up-and down-stream of 30:833 urokinase type plasminogen activator as 29:570 Serine proteinase inhibitor I 25:370 as defense proteins 25:370 Serine proteinase inhibitor II 25:370 Serine receptor 27:824 Serine-threonine-specific receptor protein kinases (S/T-RPKs) 25:520 Serjania salzmanniana 21:660 Serotonergic innervations 30:377 autoradiographic imaging 30:377 in cerebral cortex 30:377 in neonatal rats by immunohistochemical techniques 30:377 physiological role of 30:377 Serotonergic neurons 30:368,376 in raphe nuclei 30:376 role in 30:regulation of neurogenesis 30:368 Serotonergic neurotransmission 30:368 abnormalities of 30:368 effect on behavioral dysfunction 30:368 effect on neuronal differentiation 30:368 effect on proliferation 30:368 effect on synaptogenesis 30:368 Serotonergic receptors 21:68;22:21 Serotonin 21:10,17,19,50,68,84,91,95, 101,104,108;22:111,668,669,673;26: 267 ;30:367,368,369,376,377,378, 379,381,384,627 as hyperforin inhibitor 30:627 as neurotransmitter 30:367 effect on synaptogenesis 30:378 in apoptosis 30:367 in cell proliferation 30:367 in presynaptic neuron 30:381 morphogenic properties of 30:367 neurochemical connection of
724 30:368 receptor activity of 30:379,382 role in anxiety 30:368 role in austism 30:368 role in brain processes 30:367 role in depression 30:368 role in human mood 30:368 role in hypertension 30:368 role in irritable bowel syndrome 30:368 role in mental disorders 30:368 role in migraine 30:368 role in obsessive-compulsive disorder 30:368 role in panic disorder 30:368 role in pathological anxiety 30:376 role in schizophrenia 30:368 role in social interaction 30:368 role in social phobia 30:368 Serotonin (5-HT) receptors 30:376,378, 382,383 in brain 30:383 in limbic brain regions 30:383 pharmacological aspects of 30:378 type of G-protein-linked receptor 25:530 Serotonin (5-HT) re-uptake inhibitors 30:368 mechanism of 30:368 Serotonin (5-HT) synthesis 30:370,376, 377 from tryptophan 30:370 in autistic children 30:377 Serotonin (5-HT) transporter-linked polymorphic organ 30:384 Serotonin (5-HT) transporter-linked polymorphic region (5-HTTLPR) 30:381 Serotonin (5-HT) 1AR receptor antagonists 30:378 in postnatal treatment 30:378 Serotonin (5-HT)sA receptor 30:375 in brain development 30:375 in phenotypic behavioral irregularities 30:375 in purkinje cells 30:375 mRNA expression of 30:375
Serotonin action 30:378 on apoptosis 30:378 on maturation 30:378 on neuronal functioning 30:378 on proliferation 30:378 Serotonin agonists 25:531 anticomplementary activity of 25:46 role of cyclic AMP-dependent protein kinase 25:46 delayed-type allergy suppressant activity of 25:46 induced edema 25:46 Serotonin induced edema 25:46 Serotonin secretion 12:390 inhibition by K-252a 12:390 Serotonin synthesis inhibitor 30:378 parachlorophenylalanine as 30:378 Serpenticine 1:125 Serpentine 1:125;5:125;26:1060;27:782 Serpentinine 1:126,147 Serproidins 22:83 Serratenone 11:309 from hobartin 19-ol 11:305 Serratia marcescens 9:308;12:401; 22:627;26:402 Serratia sp. 4:434;12:103 (-)-Serratoline 11:321,322 1,2-rearrangement of 11:321,322 Serricomin 14:275 absolute configuration of 14:275 from cigarette beetle (Lasioderma serricorne) 14:275 from levoglucosenone 14:267,275 synthesis of 1:695;14:267,275 ent-Serrulatane 15:259 Serrulatane 15:257-260 from Eremophila drummondii 15:259 Serum ALT activity 25:471,476 of sweroside 25:471,476 ofColchicum autumnale 25:473 Serum lipid extracts 9:453 cholesteryl esters from 9:453 Serum TC 27:420 biological activity of 27:420
725
Serum transaminase 27:415,417,420 biological activity of 27:415, 417,420 Serum transaminase activity 25:469 of Curcumia longa L. 25:469 Serum triglyceride 27:404 biological activity of 27:404 Serum tumor necrosis factors (TNF-a) 25:459 Sesamin 5:461,462,703;7:219; 24:755;26:231,259,260,264 synthesis of 24:755 (+)-Sesamin 26:200,267 ;27:593 (-)-Sesamin 26:268 Sesaminol 26:249,260,264 Sesamin-type lignanes 219 Sesamol 26:249,253 Sesamolin 26:231,253,260 Sesamolinol 26:249,253 Sesamum angolense 7:407,417,423; 23:342,343 Sesamum indicum 26:249 pinoresinol from 26:249 sesaminol from 26:249 sesamol from 26:249 Sesbania drummondii 1:305,514 Sesbania punicea 1:305 Sesbania sesban 7:427,432,433; 21:506,542 Sesbania vesicaria 1:305 Sesbanimide A 1:306-320,514,521 synthesis of 1:306-320,514,521 Sesbanimide B 1:306-320 synthesis of 1:306-320 Sesbanimide B2 1:515 Seselin 20:497;23:338 Sesmin 26:246,264 Sesquicamphenes 16:136 Sesquicamphors 16:136 Sesquicarene 17:609 Sesquilignans 20:613,621 from Abies sachalinensis 20:613,621 from Chosema arbutiflia 20:644 from Eucommia utomoidis 20:644 from Salix sachalenensis 20:627 Sesquiphellandren structure 27:587
[3-Sesquiphellandrene 8:46,51,55; 21:583 from R-(+)-citronellal 8:45 synthesis of 8:45 Sesquiterpene 5:3,368,721-741 ;6:110, 125,133;7:95,98,100,102,117,120, 122,124,185-187,205,427;9:64-68, 531,534,535;13:3-52;15:227-251; 17: 8,27,28,153-154,196-197,607; 18:743-752;20:468;22:609,379; 24:175-213,847 form Stylotrichium rotundijbluim 8:58 from Ammania baccifera 9:65 from Cadabafarinosa 9:64,65 from Curcuma longa 8:52 fromFerula communis 8:59 from Fusarium sporotrichiodes 9:210,212 from Lychnophora sellowii 8:485O from Pluchea arguta (Conyza odentophylla) 9:65-68 from Zingiber officinale 8:52 in Artemisia sp. 7:209-218 molluscicidal activity of 7:427 synthesis of 8:39-59,165172;13:3-52;24:175-213 triquinanes 13:3-52 Tri-nor-Sesquiterpene 9:66 Sesquiterpene alkaloids 18:753 Sesquiterpene isocyanides 6:79,80 in Halichondride 6:79 in nudibranchs 6:79,80 Sesquiterpene isothiocyanates 25:848 Sesquiterpene ketone eremophilone 15:226 Sesquiterpene lactone 7:426;8:195-201; 24:799;27:856 in Artemisia sp. 7:202,209218,230,231 molluscicidal activity of 7:427 structure of 27:479 Sesquiterpene pyridine-type alkaloids 30:695 Sesquiterpene quinones 5:768-771 antimicrobial activity of 5:429 cytotoxic activity of 5:429 synthesis of 5:768-771
726 Sesquiterpene synthetase (cyclase) 7:109,110,123 Sesquiterpenoid intermediate 4:767 Sesquiterpenoid spathulenol 29:91 Sesquiterpenoids 8:39,9:81,249-256; 20:659,660;21:583 ;23:633,825 ;29:86 13C-NMR data of 23:634 ~H-NMR data of 23:634 costunolides as 29:97 parthenolides as 29:92 polygodial as 29:91 sesquiterpene lactones as 29:86 structures of 29:93 zerumbone as 29:97 Sesquiterpenoids drimane-type synthesis 29:127 avian myeloblastosis virus (AMV) inhibition by 127 by Jauch 29:127 Cieplak's theory in 29:127 enantiospecific total- 29:127 endo selection in 29:127 7t-facial selections in 29:127 Homer-Emmons carbon elongations in 29:127 starting from 2,3-anhydro-Darabinitol derivative 29:127 tetracyclic intermediate in 29:127 use of Sharpless asymmetric epoxidation strategy in 29:127 Sessile marine 21:3 Sesterpenes 6:110,123;20:696 Setaria cervi 21:674 Setaria FMTI 29:600 Setaria italica 25:781 ;26:476 Setomimycine 20:277 Seubert's medium 25:153 Seven membered cyclic ethers 10:209, 224-226,234 by rhodium carbenoid mediated cyclization of hydroxy c~-diazo-[3-keto esters 10:209 Seven-carbon sugars 4:175-179 synthesis by osmylation 4:175179
Seven-membered cyclic-ct-adduct 12:117 Seven-membered oxepane 10:202 Seven-membered rings 10:309-311 from five-membered rings 10:309-311 Sex pheromone 6:537-546 synthesis of 6:537-546 Sexual potency 28:4 ofbroussoflavonol G 28:4 Seychellene 8:423-425 synthesis of 8:423-425 Seychellogenin 7:270 SFORD spectrum 2:93 SFORD techniques 18:972 sGOT 30:292 activities of 30:292 sGPT 30:292 activities of 21:654;30:292 Shaagrockol B 28:675 anifungal activity of 28:675 Shaefferia cuneifolia 23:659 Shahamin C 17:12 Shanzhiside methyl ester 7:471 Shapiro reaction 13:509,578;22:238 Shapiro reaction, modified 1:460,461 Shapiro synthesis 11:84 Sharpless asymmetric dihydroxylation 16:332;18:197 ;20:592 Sharpless asymmetric epoxidation 1:265,266,487,488,507,508,510,532, 538;4:496;10:534,598,599;12:11, 18;13:621 ;14:568-571,828;16:296, 342,492;18:217 ;19:431,435,443, 478;20:450;21:422 diastereofacial-selective manner 19:492 dihydroxylation of 19:246 of 2-ethyl-2-propen- 1-ol 14:828 of 2-heptenol 19:61 of allylic alcohol 10:534; 12:11;19:45 of geraniol 19:139 osmium-catalyzed 19:246 pyrrolidines from 14:568-571 regioselective manner 19:492 Sharpless epoxidation 4:173,174,179, 186,187,203,339-345,506,514,516; 6:268,269,287,289;10:39,40,66;11:7,
727
8,59,60,83,93,94,267,268;14: 746; 18:197,204,205,244 (+)-nitramine by 14:746 enantioselective 4:343,344;6:287 of 1-cyclohexenyl alcohol 14:746 ofallylic alcohols 4:312,516 kinetic resolution by 4:342 transesterification 13:53,54 Sharpless hydroxylation 12:218 Sharpless kinetic resolution 10:236 of (+)-N-benzyloxycarbonyl-3hydroxy-4-pentenylamine 12:281 Sharpless method 4:483 in thienaycin synthesis 4:483 Sharpless oxidation 24:748 4:602;10:289;12:353 ;16:296,342; 19:463 of [3-hydroxyl olefin 16:296 with diethyl L-(+)-tartorate 16:342 in (+)-precapnelladiene synthesis 6:34 Sharpless reaction 13:203,204;19:375 Sharpless vicinal hydroxyamination 12:219 SHELXTL program series 9:8 Shermilamine A 10:245 Shermilamine B 10:245;17:23;25:820 Shermilamine C 23:272 Shermilamines D 25:820 Shermilamines E 25:820 Shewanella putrefaciens 26:69 Shiffbase 21:735 [ 1,5]-Shift 3:34 of cis-alkyl vinylcyclopropanes 3:34 1,2-H Shifts 1:331,332 Shigella flexnert 14:233 O-antigenic polysaccharide from 14:233 Shigella ambigua 26:673 Shigella boidii 26:673 Shigella boytic 25:260 Shigella dysenteriae 9:308 Shigella flexneri 26:673,1160;29:526
Shigella flexneri 14:233 O-antigenic polysaccharide from 14:233 Shigella largei-sachsii 26:673 Shigella lycopersici 25:306,313 Shigella shiga 25:260 Shigella sonnei 9:308;12:401 ;26:673 Shigella sp. 12:63 Shikimate 23:740 Shikimate 3-phosphate 11:185,186 with phosphoenolpyruvate 11:185,186 Shikimate pathway 17:471-472;23:337; 25:328 Shikimate/arogenate pathway 25:652 Shikimic acid 10:45;11:182-191; 21:298 ;23:93 ;25:928,929 antibiotics 11:182-191 synthesis of 4:561,552;13:188 Shikimic acid derivatives 29:478 (+)antitumoral activity of 29:479 as unsaturated carbauronic acid 29:479 pericosine B as 29:479 van der Walle approach to 29:478 Shikimic pathway 30:420,431,609
3-deoxy-D-arabino-2heptulosonic acid 7-phosphate (DAHP) role in 30:431 Shikoccidin 15:119 from Rabdosia shikokiana var. occidentalis 15:174 from Rabdosia umbrosa 15:175 from Rabdosia umbrosa var. latifolia 15:175 Shikoccin 15:162-164 13C-NMR of 15:165 from Rabdosia shikokiana var. occidentalis 15:174 from Rabdosia umbrosa 15:175 from Rabdosia umbrosa vat. hakusanensis 1fi: 175 from Rabdosia umbrosa var. latifolia 15:175 Shikokianal acetate 15:173 from Rabdosia nervosa 15:173
728
Shikonin 7:96,112,116 from Lithospermum erythrorhizon 7:88 Shimming 9:112 Shimofuridin A 23:199 Shimofuridin B 23:199 Shimofuridin C 23:199 Shimofuridin D 23:199 Shimofuridin E 23:199 Shimofuridin F 23:199 Shimofuridins 23:196 Shine-Dalgamo sequence 13:262 Shing and Wang 29:485 Shingofungins 21:196 Shinjudilactone 23:315 Shinjulactone C 5:800 formation from ailanthone 5:800 Shinjulactone-B 23:315 Shinjulactone-K 23:315 Shinpterocarpin 28:229 biological activity of 28:229 Shizandra chinensis B 18:589;25:476 Shizophyllan 23:141 Shimofuridin G 23:199 Shodoptera littorolides 20:245 Shogaol 9:321 ;23:846;26:475 Shonachalin A-D 7:231,232,237 from cyano derivative 10:355 from free sugars 10:393,394 from 2,3-O-isopropylidene ribofuranose 10:393 from ribofuranosyl anisyl telluride 10:385 from [3-ribosylrimethoxybenzene 10:382 synthesis of 10:355,381,382, 385,393,394 Wittig reaction of 10:393,394 Shorea disticha 23:547 Shoreaphenol 23:533 Shug Chher 25:275 Shuteria vestita 22:459 (-)-Shyobunone 16:264 Sialic acid analogues 27:116-129 aromatic sialic acid analogues 27:134-140 carbocyclic sialic acid analogues 27:140-141 long chain ester analogues
27:122-129 polar analogues 27:118-122 Sialic acids 2:309;27:103;30:423 biological function of 27:103 model for 27:111 effect on viscosity of glycoprotein 27:105 glycosidic linkage of 27:105 in transport of molecules 27:105 metabolism of 30:423 model for 27:111 structure of HA1 binding site 27:110 Sialidase 7:42,70;16:76,86,87,93,112 crystal structure of 16:93 from Streptococcus sp. 16:86,87 nojirimycin analogues inhibition with 7:42 Sialylaldolase catalyzed 11:466 condensation 11:466 Sialyltransferase 10:500,501 Sialyltransferase activity 16:81 Siamenoside I 15:24;27:15,26,27 structure of 27:27 Siamine 1:163,164 synthesis of 1:174,175 Siastatin A 10:551 from Streptomyces verticillus var. quintur" 10:550 Siastatin B 16:,/;10:550 absolute configuration of 16:77;10:550 antimetastatic activity of 16:81 from Streptomyces culture 16:76 methyl ester 16:97 N-acetyl-[3-D-glucosaminidase 10:550 neuraminidase inhibitor of 10:550 relative configuration of 10:550;16:77 stereoselective synthesis of 16:75-122 synthesis of 10:551,552 [3-glucuronidase 10:550 Sibiricine 1:203 Sibiricol 4:375,376 synthesis of 4:375,376
729
(-)-Sibirine 14:539-544 asymmetric synthesis of 14:539544 from l-prolinol 14:542 from Nitraria sibirica 14:541 Sibirine 14:744 synthesis of 14:744 Sibirinine 14: 743 from nitramine 14:743 synthesis of 14:743 3-epi-Sibirosaine 4:135,138,139 synthesis of 4:135,138,139 Sibirosamine 4:135,138,139 synthesis of 4:135,138,139 Sida acuta 5:751 Sida carpinifolia 5:752 Sida cordifolia L. 5:75;22:532 for fever 22:532 Sida rhombifolia 5:751 Sida sp. 5:751 Side effect 30:194,799 of analgesic alkaloid 30:799 of opioids 30:194 Sideritis angustifolia 29:687 Sideritis arborescens 25:249,250 Sideritis foetens 25:250,254;29:102 Sideritis gomerae 25:249 Sideritisjavalambrensis 25:250,263, 274;29:102 Sideritis leucantha 22:429 Sideritis lycopersici 25:308,314 Sideritis marmorea 30:260 trimethoxykaempferol from 30:260 Sideritis mugronensis 25:250; 29:102,701 Sideritis nutans 25:249 Sideritis raeseri 30:258 apigenin from 30:258 Sideritis shiga 25:260 Sideritis sp. 5:658;30:259 p-coumaroylglucosides from 30:259 Sideritis varoi 25:250 Siderophores 9:537-557;19:791-833 from bacteria 9:537-557 from flourescent Peseudomonads 19:791-833 peptide 9:537-557
Sidnutol 25:249 Sidnyaxanthin 6:151 Sidnyum turbinatum 28:643 1-heptadecanyl sulfate from 28:643 1-hexyl sulfate from 28:643 1-octadecanyl sulfate from 28:643 sodium (2S)-2,6,10,14-tetramethylpentadeca- 1,18-diyl sulfate from 28:643 Sidonops microspinosa 28:681 Sieberoside I 25:191,196,225 Sieberoside II 25:196,225 Sieversin 7:236 [ 1,2]-Sigmatropic (Stevens) rearrangement 6:315 Sigmatropic 1,3-H-migration 18:166 [2,3]-Sigmatropic elimination 12:11 of PhSeOH 12:11 [1,5]-Sigmatropic H shift 10:70 Sigmatropic migration 19:208 with phenylselenium 19:208 [2,3]-Sigmatropic rearrangement 1:401,560;3:354;6:316;8:209;11:15, 16,24,30,45,46,48,49,188,326,327; 12:93,95,467;13:72,418,519,589; 14:533,534;16:173,255,621, 622-623,627 ;19:259;24:67,68 for C-S to C-O conversion 1:560 of allylic sulfonium ylide 16:255 ofsulfoxides 1:560 ofallylic sulfoxides 11:326,327 of 6-alkenyl-4-oxapyran-2-ones 10:460 of allylic (alkyl) ketene acetal 10:417 of allylic azides 10:418 of allylic thiocyanates 10:418 of allylic trichloroacetimidates 10:421 ofallylic sulfoxides 11:326,327 suprafacial 16:627 [3,3]-Sigmatropic rearrangement 1:53, 228,401 ;3:228;4:522 ;6:222,224,225; 8:245,251 ;10:333,416-420;11:15, 16,45,46,48,49,188;12:95,193,249;
730
13:418,519,589;14:625;19:6;24:4,67, 68,81-83;21:386 Sigmatropic rearrangement 12:246-250; 13:420,564;16:340 [ 1,3]-Sigmatropic rearrangement 16:254,617 [1,5]-Sigmatropic rearrangement 4:333; 11:27,3:289 [ 1,7]-Sigmatropic shift 2:128 [1,5]-Sigmatropic shift 24:763 [1,5]-Sigmatropic shift of hydrogen 12:182 [3,3]-Sigmatropy 10:235 Sigmoidin A 28:229 biological activity of 28:229 Sigmoidin B 28:229 biological activity of 28:229 Sigmosceptrellins A-C 9:20,22,24-29 absolute stereochemistry of 9:16 from Sigmosceptrella laevis 9:16 X-ray analysis of 9:16,20 Signal pathway-associated proteins 25:370 acyl-CoA binding protein 25:370 calmodulin 25:370 lipooxygenase 25:370 prosystemin 25:370 nucleotide diphosphate kinase 25:370 Signal reception 30:377 in autistic children 30:377 Signal transduction 21:20 Signal transduction mechanisms 25:518 Signal transduction pathways 25:514, 515 Signal transductors/activators of transcription (STATS) 25:519 Sih's compactin synthesis 13:593 Silandrin 26:255 as antihepatotoxic agent 26:255 Sildenafil 30:155 used for erectile dysfunction 30:155 Silene fortunei 26:46,47,55 Silenejenisseensis 24:150,151, 26:45,46,47 Silene latifolia 26:45 Silene rubicunda 26:45 Silene sp. 26:45
Silene succulenta 26:45 Silene villossa 26:45 Silene vulgaris 26:47,48 Siler trilobum 29:83 Silica gel column chromatography 30:62 in isolation of triterpenoid fractions 30:62 Silicatein 25:717 Silicine 5:126 20-epi-Silicine 5:126 Silicon ethers 6:262 in glycosidation 6:262 Silicon-containing nucleophiles 14:472 Siliconizing agent 22:375 Silicotungstic acid 22:108 Siliquariaspongia japonica 25:723,759 Siloxane bridged oligonucleotides 13:271 Siloxy methyl 8:179,180 [3-Siloxyacetals 14:483 with organometallic reagent 14:483 [1,3]-Siloxy-Cope ring expansion 8:246 Siloxydiene 4:334 asymmetric Diels-Alder reaction with 4:34 Silphinene 3:62,118;8:165,166; 13:9-11,20;26:864,865,866,867,871 from Silphium perfoliatum 13:8 synthesis of 3:8,9,16,25 total synthesis 8:165,166 Silphinium perfoliatum 8:165;13:8,11 silphinene from 8:165;13:8 (-)-silphiperfol-6-ene from 13:8,11 Silphiperfol-5-en-3-ol 9:515,516 7c~H-Silphiperfol-5-ene 3:6,63 synthesis of 3:15 7[3H-Silphiperfol-5-ene 3:6,63 synthesis of 3:15 13 (+)-Silphiperfol-6-ene 13:11 from Silphium perfoliatum 13:11 Silphiperfol-6-ene 3:6,8,14,15,62 synthesis of 3:14,15 9-epi-Silphiperfol-6-ene 3:62
731 Silver (II) oxide 5:769 oxidative demethylation with 5:769 Silver cyanide 12:113 allyl isocyanide from 12:113 Silver oxide 11:86 oxidation with 11:86 Silver oxide method 4:386 in prenylation methods 4:386 Silver staining 17:396 Silver sulphamate 9:433 Silver triflate 3:216 in C-glucosidation 3:216 Silver trifluoroethane sulphonate method 4:323,324 Silybin 26:255 as antihepatotoxic agent 26:255 Silybum marianum 5:496;26:255 silymarin from 13:660 Silydianin 8:166-168 as antihepatotoxic agent 8:166 synthesis of 8:166-168 Silyl enol ether 3:129 reaction with 1-phenyl-2-buten1-one 3:129 reaction with unsaturated ketones 3:129 Silyl enolate Claisen rearrangement 1:563;2:685 Silyl group 1:452,453 removal with n-Bu4 NF 1:452, 453 Silyl ketene acetals 10:422,423 Claisen rearrangement of 10:422,423 O-Silyl ketene acetals 3:243 in Claisen rearrangemment 3:243 Silyl Pummerer rearrangement 4:550 Silylacetylenic reagents 14:473 Silylated phosphonium ylides 4:546 reaction with acid silyl esters 4:546 synthesis of 4:563 Silylation 6:16,19,20,25,26,30-33, 39-41 ;11:338,369;19:518 Silylenol ethers 4:475-477 c~'-Silyloxy (E)-enone 19:59
0~-Silyloxy propargylsilanes 10:227 by exocyclic ring closure 10:227 synthesis of 10:227 (S)-3-Silyloxy-2-methylpropanal derivatives 30:19 Silyloxydienes 4:113 in cyclocondensation 4:113 Silyl-Wittig reaction 14:461,463,464 Silymarin 5:496;13:660;25:612,614; 26:754 Silymonin 26:255 as antihepatotoxic agent 26:255 Silyvinylalane 12:295 Simaba amara 7:369,381 Simaba cedron 7:392 Simaba cuspidata 7:369,381 Simaba guianensis 26:815 Simaba multiflora 7:369,380,396 Simalikalactone-D 7:391,392,395, 396,398;11:72,79;26:815,816 Simarinolide 23:299 Simarolide 7:392,396;11:71 Simarouba 26:837 Simarouba glauca 13:660 glaucarubin from 13:660 Simaroubaceae species 11:71 Simaroubaceous plants 7:369-404 Simaroubolides 22:146 Simerestis welwitschii 23:660 Simiarenol 20:17 from Artemisia anomala 7:218 from Artemisia argyi 7:218 SIMM 21:736 Simmons-Smith cyclopropanation 6:72;11:29,30;16:703 Simmons-Smith reaction 6:5,234,235; 8:34;14:490;24:190 annulation by 6:5 diastereoselective 14:487-489 of chiral vinyl ether alcohols 14:487,488 of c~,p-unsaturated acetals 14:489-491 Simmons-Smith reagent 14:490 chelation controlled delivery 1:637 cyclopropanation with 1:631,632 Simocyclinon 29:319 antibiotic activity of 29:319
732 cytostatic effects of 29:319 structure of 29:319 Simple isoquinolines 21:84 Simplexin 20:234 SIMS 21:731,732 Simvastatin 15:450;22:251,253 Sinapaldehyde 5:471 Sinapic acid 5:469,470;23:744,771; 25:434,653,655,920;28:262 in broccoli 28:262 in citrus juices 28:262 in kale 28:262 in leafy brassicas 28:262 Sinapis alba L. 25:781;26:612,1074 Sinapis arvensis 29:618 1 '-O-S inapo yl- 6'- O-galloyl- [3-Dglucopyranose 26:359 Sinapyl alcohol 5:767,771,774,775; 25:653;27:760 polymerization of 27:760 (Z)-Sinapyl alcohol 5:472 Sindbis virus 17:135;26:223 Sinefungin 1:408-410;11:437,438; 24:547;26:830 antiviral microbial-derived compound 24:547 isolation of 19:177 synthesis of 1:408410,11:437,438 Sinensetin 23:747;26:746 Single nucleotide polymorphisms (SNP) 30:384 Single pathway modeling 23:18 Single-helix configuration 23:122 Singlet oxygen 3:439,440 addition to isoquinolines 3:439,440 as dienophile 4:612 Singmadocia symbioltica 25:902 Sinigrin 26:481 Sinomenine 25:472,476 hepatoprotective effect of 25:472 Sinomenium acutum 25:476 (-)-Sinularene 6:75 from Sinularia mayi 6:75 synthesis of 6:75,76 (+)-5-epi-Sinularene 6:76,77 synthesis of 6:76,77 Sinularia sp. 21:276;29:91
Sinularia dissecta 23:170;25:704 Sinularia flexibilis 25:690 Sinularia nanolobata 25:690 Sinularia sp. Sinularin 8:15 11-epi-Sinulariolide 17:22 12-epi-Sinulariolide 17:22 11-epi-Sinuriolide 17:28 Siol acetate 724,728 Siphocampylus verticillatus 30:204 antinociception effect of 30:204 piperidine alkaloid hydrochloride from 30:204 Siphonaria atra 17:25 Siphonaria baconi 17:25,28 Siphonaria diemenesis 17:24 Siphonaria laciniosa 17:25 Siphonaria maura 17:25,26 Siphonaria normalis 17:25,27 Siphonaria sp. 17:23,26,28 Siphonaria zelandica 17:25 Siphonarin A 17:25,27 Siphonarin B 17:25 Siphonoborgia sp. 9:37 (22R, 23R)-22,23- methylene cholesterol from 9:317 Siphonodictyal-A 15:297 Siphonodictyal-B 15:293,298 Siphonodictyal-C 15:298 Siphonodicytal-D 15:300 Siphonodicytal-E 15:294 Siphonodictyoic acid 15:293 Siphonodictyol-G 15:293 Siphonodictyol-H 15:298 Siphonodictyon coralliphagum 28:669 bis(sulfato)cyclosiphonodictyol A from 28:669 siphonodictyal D from 28:669 siphonodictyols G from 28:669 Siraitia grosvenorii 15:5,22; 27:6,7,14,15 mogroside IV from 27:14 mogroside V from 27:6,7,14 siamenoside I from 27:15 Siraitia siamensis 15:24;27:14,15 siamenoside I from 27:15 Sirenin 17:609 (-)-Sirenin 6:544-546 from (-)-perillaldehyde
733 6:545,546 synthesis of 6:544-546 Siricic acid methyl ester 7:132,133 from diacetyl dimethyl bartogenate 7:132,133 from Terminalia siricia 7:132 (-)-Siringaresinol 27:503 structure of 27:504 Siroheme 9:583,586 Strychnos nux vomica L. 22:533 Sisafolin 23:353 Sitakisogenin 27:45,48 structure of 27:48 Sitakisosides I-IX,XI-XIII,XVI,XVIII 27:41,45,47,48 structures of 27:48 Site-1 proteases 25:390 Siteselective a-lithiation 24:9 Sitobion avenae 27:213 Sitoindoside II 26:219 as chemopreventive agent 26:219 Sitophilus granarius 18:698;24:101 Sitophilus oryzae 9:299;21:595,618; 24:716 [3-Sitosterol 2:129,9:288,289,399,412, 413 ;20,707 ;21:690;22:482 ;23:797; 26:358;27:477 androstenedione from 9:411 from Salvia divaricata 20:702 from Salvia montbretti 20:704 from Salvia nemorosa 20:702 from Salvia pomifera 20:702 microbial degradation of 9:411 Sitosterol 5:753,7:124,9:454 (24R)-24-ethyl cholest-5-en-3bol) 9:447 from Salvia glutinosa 20:707 Sitosterol 3-glucoside 7:218 from Artemisia rupestris 7:218 from Artemisia valentina 7:218 Sitosterol palmitate 9:472,473 13-Sitosterol glucoside 22:609,610 [3-Sitosterol-3-O-13-D-glucoside (phytosterol glycoside) 29:590 effects on PEP 29:590 Sitosterone 9:288,289 [3-Sitosteryl linoleate 9:461
Sitosteryl stearate 9:454 Sitterash 23:655 Sium latifolium 5:724,728,20:6 Sium latijugum 5:728 Sivasinolide 27:556 Six-membered cyclic ethers 10:209 by rhodium carbenoid mediated cyclization of hydroxy ~-diazo[3-keto esters 10:209 Six-membered ring 8:175 Skaanderup and Madsen 29:496 carbaoxirose/carbaoxetoses synthesis by 29:496 Skeletal rearrangements 7:159-168 Skimiate pathway 25:652,653 Skimmianine 3:385,386;22:534,535,542 Skimmin 3:224 Skin cancer 5:747 Skin diseases 30:732 Skin inflammation 30:323 anthrones used for 30:323 SKK Moth 1:704-706 juvenile hormone from 1:704706 SK-MEL-2 (skin) 22:621 SK-OV-3 (ovarian) 22:621 Skullcapflavone II 30:288 structure of 30:288 Skyrin 22:649 (+)-Skytanthine 21:128 Skytanthine 7:444 Slaframine 1:289;14:568;27:252 biological activity of 27:252 synthesis of 1:289 (+)-l-epi-Slaframine 12:309 synthesis of 12:309 (+)-6-epi-Slaframine 12:311,312 synthesis of 12:311,312 (-)-Slaframine 18:386 activity of 12:306 biosynthesis of 12:307 enantioselective synthesis of 12:309,310 relative configuration of 12:309,310 synthesis of 12:307-312;16:484 Slaframine alkaloids 27:250,255 as muscarinic agonist 27:255
734 Slaframine type alkaloids 27:250 HPLC determination of 27:251 Slave-keeping ants 6:454 Sleeping sickness 2:293,302 Small cell lung cancer 27:799,802 Smenochromene-B 15:295 Smenochromene-C 15:295 Smenochromene-D 15:295 Smenodiol 15:293,297 Smenoquinone 5:434,425 antimicrobial activity of 5:434, 425 Smenorthoquinone 5:431,432;15:291, 292 antimicrobial activity of 5:434, 435 Smenospondiol 5:431-433,435437,439; 15:292,293 Smenospongia aurea 5:437 8-epichromazonaral from 15:291 Smenospongia sp. 5:429,430,432434,439 Smenospongiarine 5:431-433,435,436 Smenospongidine 5:431-433,435,436 Smenospongine 5:434,425 antimicrobial activity of 5:434, 435 cytotoxic activity of 5:435 Smenospongorine 5:431,432,433,436 Smilagenin 7:138 from Echinophora lamellose 7:136 Smilax glycyphylla Sm. 27:17 glycyphyllin from 27:17 Smiles rearrangement 23:415 Smirnovia turkestana Bunge 27:517 Smith 29:371,402 rhazinilam synthesis by 29:371 Smith degradation 1:436,439;5:197 Smith indole synthesis 1:155 Smith reaction 7:270 Smith rhazinilam synthesis by 402 Smith synthesis 12:25,26;30:13-19 of avermectin oxahydrindene subunit 12:25,26 of (-)-discodermolide 30:13-19 Smith-Leml-Opitz syndrome 23:582 Smodingium argutum 9:318 Smoke-bush 23:657
Smooth muscle contraction 24:875-925 of Kampo medicines 24:875-926 Smooth muscle Na+/H+ antiporter system 12:390 Smooth muscle relaxation 24:875-925 as biological action 24:875 of Kampo medicines 24:875-926 SNl-products 11:319,320 SN2 reaction 11:207;14:747;16:296 oftriflate 16:296 S N 2 type cyclocarbamation 12:479 SNZ-alkylation 13:585 SNZ-displacement 13:589;14:156 SN2-nucleophiles 16:415 SNZ-type condensation 14:147 SNZ-type reaction 14:269 Snail enzyme 7:268 Snake 8 kDa polypeptide toxin ~xbungarotoxin 25:528 Snake bite 30:691 treatment of 30:691 use of Crossopetalum gaumeri 30:691 SNAr reaction 20:410 Snechocystis sp. 25:718 SNIF-NMR 13:334,336 33S-NMR 9:188,119 of phenyl cyclohexyl sulphones 9:188,119 SN'-process 11:323 intramolecular 11:323 (+)-Snularene 6:78,79 by Claisen rearrangement 6:78,79 by intramolecular [4+2] cycloaddition 6:85 by intramolecular type-I Mg-ene reaction 6:76,77 by mesylation 6:76,77 by O-methylation 6:76,77 by Wittig condensation 6:85 by Wittig olefination 6:79 from bicyclo [3.1.0] hexan-2-one 6:79 from bicyclo [3.2.1] octanone 6:78,79 from Collins-Wege intermediate 6:78,79 from exo (endo)-methylbicyclo
735
[2.2.1 ]-hept-5-ene-2-carboxylic acids 6:76 from norbornene 6:76,77 synthesis of 6:76-79,85,86 Snyder et al. 29:214 miltirone synthesis by 29:214 Sobrerol 29:83 activity in mam-2 assay system 29:83 activity in GST assay system 29:83 activity in RAS assay system 29:83 Social phobia 30:368 role of serotonin (5-HT) 30:368 Soda Fabrik 28:71 synthesis of 29:439 vitamin A synthesis by 28:71 Sodium (or potassium) 2,6-dimethylheptyl configuration of 28:642 Sodium amalgam 11:349 desulfonylation with 11:349 Sodium artesunate 13:657;22:154 Sodium bistrimethylsilylamide 6:540 cyclization by 6:540 Sodium borohydride 8:468-470 Sodium cyanoborohydride 11:87 reduction with 11:87 Sodium dodecyclosulfate-polyacrylamide 25:499 Sodium hexamethyldisilazide 13:63; 24:24,25 methylation with 13:63 Sodium hydrotelluride 11:81,82,92,93 reduction with 11:81,82,92,93 Sodium metaperiodate 25:134 Sodium methanethiolate 6:340 Sodium naphthalene 11:371 Sodium naphthalenide 6:541,542 Sodium phenylselenide 6:489,490 reaction with (+)-canadine 6:489,490 Sodium salt of caffeic acid tetramer 24:742,743 anti-HIV activity of 24:742 Sodium triacetoxyborohydride 22:279, 286 Sodoponin 5:171 from Rabdosia eriocalyx 15:171
from Rabdosia setschwanensis 15:174 from Rabdosia ternifolia 15:175 Sodoptera littorais 18:772 Sofalcone 22:425,431 Soft acids/bases 3:409 Soft agar transformation assay 30:592, 593 for isolation of (7R,8S,7'R,8'R)30:(+)-7'-acetylpicropodophyllin 30:593 for isolation of lignan 30:593 Soilborne fungi 21:181 bioactive metabolites from 21:181 Soilborne phytopathogens 21:182 biological control of 21:182 Solamargine 21:84 Solamin 18:202-206 asymmetric synthesis of 18:202206 hemi-synthesis of 18:219-220 Solamum melongena 23:757 Solanaceae 22:720,723 Solanaceae alkaloids 11:229 steroidal type 11:229 Solanaceous plants 17:395 Solanaceous sp. 25:304,368 Solanaceous steroidal glycoalkaloids 26:467 Solanapyrone A 17:475;4:620 bioietric synthesis 4:620 synthesis of 4:598,599 solanapyrone B 4:598 Solandelactones 24:455 FPTase inhibition by 24:455 Solanesol 8:66,78 Solanidane 7:17-22,24 Solanidane alkaloids 23:574 structure of 23:574 Solanidane N-oxide 7:23 Solanidane-induced teratogenicity 23:573 22S,25R-Solanidanes 23:585 Solanidine 7:18,19,21;23:573,584 25S-Solanidine 23:584 22R-Solanidine 7:18,22 22S,25R-Solanidine 7:19-21 22S,25S-Solanidine 7:22,23
736 Solanidine-N-oxide 23:584 22R,25S-Solanidines 7:20 Solanine 21:79,80,96,98,102,109 c~-Solanine (solatriose) 7:18-20,22; 23 ;21:80;23:573,584 ;25:300,305, 311;26:818,868 Solanum acaule 23:343 Solanum alkaloids 7:17,19,21,22,24 Solanum americanum 22:532;29:611 Solanum carolinense L. 22:532 for epilepsy and convulsions 22:532 Solanum dasyphyllum 22:532 as anticonvulsant agent 22:532 Solanum dimidiatum 22:739 Solanum dulcamara 20:135;29:591 Solanum eleagnifolium 7:19 Solanum incanum L. 22:532;28:400 for epilepsy 22:532 Solanum indicum L. 20:135;22:532 Solanum kwebense 22:739 Solanum mammosum 7:427 Solanum melongena L. 20:135;21:239; 22:532,721;29:591,611 Solanum nigrescens 21:662 Solanum nigrum 22:532 as anticonvulsant agent 22:532 Solanum ridellii 7:23 Solanum sodomaeum L. 22:532 as antiepileptic agent 22:532 Solanum sp. 7:21,22;25:293 Solanum torvum 22:532 Solanum tuberosum 7:20,22;20:135; 22:721 ;26:936,941 ;29:582,584,600 Solanum umbelliferum 20:489 steroidal alkaloids from 20:489 Solanum xanthocarpum 20:135;22:532 for epilepsy 22:532 Solaria cervi 26:467 Solarmargine 26:817 (x- Solarmargine (chacotriose) 26:819 Solasodine 7:19,21;15:28; 20:489,490;22:28 ;23:573,575,584 Solasodine glycoside 7:19 from Solanum elegnifolium 7:19 Solasodine-3-O-13-D-glucopyranoside 20:489
Solaster borealis 15:55 solasteroside from 15:55 Solasteroside A 15:55 from Solaster borealis 15:55 Solavetivone 26:461 Solenopis aurea 6:423 piperidine venom alkaloids in 6:423 Solenopsin A 6:426,427;16:453 antibiotic activity of 16:453 from methylvinyl ketone 6:426,427 from oxatropane 6:433,434 hemolytic activity of 16:453 insecticidal activity of 16:453 synthesis of 6:426,433,434,448 Solenopsin B 6:430 absolute configuration of 6:430 enantioselective synthesis of 6:429,430,433,434 from oxime sulfonate 6:433,434 (+)-(S,S)-Solenopsin-A 6:431,432 asymmetric synthesis of 6:431,432 Solenopsins 6:422-434;21:89 synthesis of 6:422-434 Solenopsis A 1:389,390 Solenopsis carolinensis 6:423 piperidine venom alkaloids in 6:423 Solenopsis conjurata 6:450 indolizidine alkaloids in 6:450 piperidine venom alkaloids in 6:423 Solenopsis eduardi 6:423 piperidine venom alkaloids in 6:423 Solenopsis fugax 6:436 piperidine venom alkaloids in 6:436 Solenopsis geminata 6:423 piperidine venom alkaloids in 6:423 Solenopsis invicta 1:682;3:273;5:228 pheromone synthesis 1:682 piperidine venom alkaloids in 6:423
737
Solenopsis littoralis 6:423 piperidine venom alkaloids in 6:423 Solenopsts molesta 6:436 pyrrolidine venom alkaloids in 6:436 Solenopsts pergandei 6:423 piperidine venom alkaloids in 6:423 Solenopsts punctaticeps 6:423 pyrrolidine venom alkaloids in 6:423 Solenopsts richteri 6:423 piperidine venom alkaloids in 6:423 Solenopsts saevissima 6:423 piperidine venom alkaloids in 6:423 Solenopsts sp. 6:450,454;11:231;27:246 alkyl-l-piperideine in 6:422 arthropod alkaloids from 11:231 Solenopsis texanas 6:436 pyrrolidine venom alkaloids in 6:436 Solenopsis xyloni 6:422,423 2-methyl-6-alkyl- 1-piperideine in 6:422 piperidine venom alkaloids in 6:422,423 Solid tumors neovasularization 25:593 Solidago altissima 19:247 Solidago saponins 15:191 Solidago sp. 6:28 kolavenic acid from 6:28 Solidago virgaurea 21:634,660,662 Solid-phase extraction 21:529,577 Solid-phase method 6:405 in MDP analogs synthesis 6:405 Solmonella anatum 8:101,103 Solon 22:427,440;25:618 Solricin 26:135 26:362 Solunum xanthocarpum 22:532 Solution conformation 24:319-321 Solvent extraction 21:575 Somatostain 22:25;25:265 as A~ adenosine agonists 25:265 Somatostatin analog 27:795,796 Somatostatin receptor 21:72;22:26; 25:530
type of G-protein-linked receptor 25:530 Somatostatine receptor 21:72 Somatotropin (STH) 13:661 ;25:265 Songistatin 1 19:580 Sonic hedgehog gene 23:563,580 Sonic hedgehog proteins 23:581 intramolecular autoprocessing reactions of 23:581 Sonneratia alba 7:176,194,195 Sonneratia apetala 7:188 Sonneratia caseolaris 7:176 Sonneratia grifithie 7:195 Sonneratia ovata 7:176 Sonneratia sp. 7:176 Sonodione 30:566 from Hernandia sonora 30:566 Sonomolide A,B 21:237 Sophora chrysophylla 15:522 Sophora flavescens 9:148;25:93;26:487; 29:705 Sophora griffithii 9:149 Sophorajaponica 26:1142;29:573 Sophora significantly 22:431 Sophora sp. 30:205 sophoranol from 30:205 Sophora subprostrata 22:425; 25:93;29:774 Sophora tomentosa 15:522 (-)-epilamprolobine from 15:522 (+)-epilamprolobine N-oxide from 15:522 5-(3'-methoxycarbonylbutyroyl) amino me thyl-tra ns-qu inolizidine N-oxide from 15:522 Sophora tonkinensis 27:275 Sophoradin 22:425,432;25:612 Sophoradiol 25:95,111,112,115,116,118 Sophoradiol glucoronides 25:111, 114,119 Sophoradiol glycoside 25:115 Sophoradiol monoglucuronide (SoMG) 25:111,112,113,114,115,121 Sophoradiol OG 25:94,99 Sophoraflavoside 25:96 Sophoroflavoside III 25:96 Sophoroflavoside IV 25:96 3-Sophoroside 23:746
738 Sophorosyl ([3-D-glucopyranosyl(2---~1)-[3-D-glucopyranosyl) sugar unit 15:20 Sopongiacidin B 25:798,799 Sorangium cellulosum 25:779 Sorbic acid 10:149;152 Sorbinil 22:171 D-Sorbitol 1:307 Sorbitol dehydrogenase 25:472 Sorbus aucuparia 10:152;23:342 Sordaria fimicola 21:209,227,228,241 Sorelline 9:178;11:310,311 formation of 11:310,311 from hobartin- 19-ol 11:305 from (+)-20-hydroxyhobartine 11:323 indole-protected 11:310,311, 328-330 synthesis of 11:326-328 Sores 30:616 tricyclic acylphloroglucinols in 30:616 Sorgassum tortile 25:839 Sorghum 21:502-505,516,535 Sorghum bicolor 9:322,344 ;21:505 ;29:593,601 Sorgoleone 26:370 Sorivudine 24:474,486 as anti-viral agent 24:474,486 Sorocea bonplandii 17:458 Soroceal 28:201 from moraceous plants 28:201 Sorocein F 28:230 biological activity of 28:230 SOS chromotest 22:623 Sotmatal opening 27:345 for abscisic acid 27:345 Sotolon 13:318,319 Soulamea soulameoides 7:396 Soulamea tomentosa 7:369,381 Soulameanone 7:395,396 Soularubinone 7:381,382,392 Souliea 25:180 Sour orange 23:747 Sowdanones 25:705 Sowden method 4:197,203 in L-glycero-D-mannoheptose synthesis 4:197,203
Soya bean flour 9:412,413 enzymatic hydrolysis of 9:412,413 Soyabean saponins 25:222,223 hypocholesterdemic effects of 25:222 Soyapogenin III 25:95 Soyapogenin IV 25:95 Soyapogenin V 25:95 Soyasapegenol E 25:97,115,120 Soyasapogenol A glycoside 103 Soyasapogenol B 15:187;23:416,517; 25:94,95,102-104,111,112,115, 118-120,184-186,203 Soyasapogenol B glucuronides 25:114, 119 Soyasapogenol B monoglucuronide (SBMG) 25:102,121 Soyasapogenol BOG 25:99 Soyasapogenol D 23:416 Soyasapogenol E glucuronides 25:114 Soyasapogenol F 23:416 Soyasaponin 25:90 Soyasaponin I 25:95,99,102,103,112, 114,115-118,120,203 Soyasaponin A 21:674 Soyasaponin A3 15:196 from Glycine max 15:196 Soyasaponin A3 25:95,104 Soyasaponin Ab 21:675 Soyasaponin B 25:115,116 Soyasaponin I 15:187;21:642,643,659, 675;24:215 22,24-di-O-methyl soyasapogenol B from 7:157,158 Soyasaponin I and II 25:222,223 Soyasaponin II 21:665;25:103,115, 116,119 Soyasaponin III 25:103,110,112, 114,116-118 Soyasaponin IV 25:103,203 Soyasaponin Me ester II 25:203 Soyasaponin Me ester III 25:203 Soyasaponin V 21:659;25:104 Soyasaponin [3g 21:675 Soyasaponins 27:398 anti-obesity action of 27:398 biological activity of 27:399
739
from soybeans 27:398 structure of 27:398 Soyasaponins I-IV 25:101 Soybean isoflavones 28:286 in humans 28:286 Soybean lipoxygenase-1 30:225 studies on 30:225 Soybean trypsin inhibitor (SBTI) 30:843,836 Soymida febrifuga 29:585 SP-175 22:538,515 Sp6 RNA polymerase 4:306 enzymatic ribonucleotide synthesis 4:306 Sparteine 14:738,739;21:73,91,95, 98,109;22:23,34,35 ;27:279,280 biosynthesis of 14:738,739 from L-lysine 14:738,739 (-)-Sparteine 15:520;22:14 (+)-Sparteine 22:17 Spartidienedione 30:715 structure of 30:715 Spasmogenic 24:799 biological activity 24:799 Spasmolytic activity 23:358;28:257, 293 ;30:264,561,748 of Hernandia moerenhoutiana 30:561 of Hernandia voyronii 30:561 of imperatorin 23:350,358 of plant polyphenols 28:257,293 of Thymus satureioides 30:264 on guinea pig ileum 30:748 on smooth muscles 30:264 Spasmolytics 17:395 Spasms 22:522 Hedeoma pulegioides L. for 22:522 Ledebouriella seseloides for 22:524 Spatane diterpenoids 6:39 biological activities of 6:39 from Dictyotaceae 6:38 synthesis of 6:39,40 tricyclo [5.3.0.0 2'6] decane in 6:38,39 (+)-Spathulenol 15:248 from Eremophila cuneifolia 15:248
from Eremophila paisley 15:248 from Eremophila racemosa 15:248 from Eremophila arummondi 15:248 from Eucalyptus spathulata 15:248 from Salvia sclarea 20:660 (-)-Spathulenol 16:245 Spathulenol 9:531 ;26:402; 30:607,715,724 structure of 30:724 Spatol 6:39 biological activities of 6:39 (+)-Spatol 6:40,41 by aldol cyclization 6:40,41 synthesis of 6:40,41 Specific rotations 2:259 ofproaporphine dienones 2:259 (-)-Specionin 9:70-72;10:425;20:486 antifeedant activity of 10:425 synthesis of 10:425,426 (-)-Spectalinine 20:486 Spectinomycin 11:216 biosynthesis of 11:216 by TDP-glucose oxidoreductase 11:216 from glucose 11:216 from Streptomyces sp. 11:216 Spectral data 6:148,150,155,156; 26:1078 for HMTP 26:1078 of acetylenic carotenoids 6:148,150,155,156 of apparicine 6:505 of brafouedine 6:503-506 of 19'-butanoylfucoxanthin 6:138 of 3,14-dihydroellipticine 6:518 of dinklageine 6:524,526 of ellipticine 6:519 of epchrosine 6:505 of gentianine 6:528,529 of gyroxanthin 6:162 of 16 (S)-hydroxy- 16,17dihydroapparicine 6:505 of 10-hydroxyellipticine 6:518 of 18-hydroxyellipticine 6:515,519
740
of isobrafouedine 6:503-506 of 8-methoxy-8,10dihydrogentianine 6:528,529 of 7-O-[4-methyl-5 hydroxyethyl nicotinoyl] strychnovoline 6:526 of 17-oxoellipticine 6:509,519 of N-b-oxyellipticine 6:519 of N-b-oxy- 17-oxoellipticine 6:515,519 of strellidimine 6:516,518 of strychnovoline 6:524,526 of 3,14,4,21-tetrahydroellipticine 6:518 Spegatrine 13:387 Spergulagenic acid A 7:144,145 Spergularia ramosa 26:49 Spermatophyta 18:740 Spermicidal activity 26:53 of Gypsophila paniculata 26:53 Spermidine 9:74;23:519;26:932,1263 Spermidine alkaloid 9:73 synthesis of 16:423 Spermine 23:519;26:932,1263 Spermine alkaloids 9:75;13:650 Spermostrychnine 26:1064,1065,1066 Sphacriales 9:203 Sphaeranthus indicus 9:145 Sphaerechinus granularis 15:104 Sphaereophorus globosus 5:310 Sphaerodiscus placenta 7:304-306 22-dehydrohalitylosides D,E from 7:298 halitylosides A,B,E from 7:298 placentoside A from 7:298 Sphaerophorin cetraria 9:317 Sphaerotheca pannosa 27:178 Sphaerotrichia 26:1121 Spheciospongia vagabunda 9:37 (24S,25 S)-24-26-c yc locho lestero 1 from 9:37 Sphenostylins A 7:413,414 Sphenostylins D 7:413,414 Sphigosine- 1-phosphate 25:535 Sphigosyl-phosporylcholine 25:535 Sphingadienine 1:681 Sphingofungins 18:460,469 Sphingolipid biosynthesis 22:248
Sphingolipid receptor C a 2+ channels 25:535 Sphingolipid receptors 25:534 Sphingolipids 13:533 Sphingosine 12:412;13:531;18:786 D-(+)-erythro-Sphingosine 18:461 Sphingosine derivative 25:721 Sphingosine-related marine alkaloids 23:185 Sphinxolide 10:153;17:17 antitumor activity of 17:17 Sphinxolides B-G 26:1207,1208,1209 Sphizomelme 25:333 Sphondin 22:539,522 Spiciformin 7:211,231 ;27:567 Spider mite 1:702 hatching inhibitor 1:702 Spigelia anthelmia 26:852;28:400 Spilantes leiocarpa 24:103 Spilanthes alba 10:152;21:378;24:690 Spilanthes mauritiana 21:378;22:532 Spilanthes oleracae 24:689 Spin quantum number 9:110 of 170 9:110 of 33S 9:110 of 77Se 9:110 of ~25Te 9:110 Spin trapping experiments 9:573 Spinaceamin 15:328 Spinacetin 7:228 Spinacia oleracea L. 22:482;29:586 Spinasterol 9:470 palmitate ester of 9:470 (+)-Spinescin 26:267 Spingosine kinase 25:269 Spiniferin- 1 6:72 from Pleraplysilla spinifera 6:72 (+)-Spiniferin- 1 6:73,74 by intramolecular cyclopropanation 6:73,74 by ring expansion rearrangement 6:73,74 synthesis of 6:73,74 Spiniferin-1 and 2 21:361 Spinning band distillation 11:359 Spinning-band column distillation 11:288 (-)-Spinosine 26:823 Spinosyn A 28:405
741
Spinosyn B 28:405 structure of 28:405 Spinus tristis 5:836 hemoglobin components of 5:836 Spiphonodicyton coralliphagem 25:694 Spiramycin 5:613,614 Spiranolide 11:160 Spirastrella abata 25:722 Spirastrella sp. 25:719 Spirastrella spinispirulifera 25:759 Spirilloxanthin 20:591 Spiro (4,5) decane skeleton 25:851 Spiro [4.5] decane 10:315 synthesis of 14:544-546 Spiro [4.5] decane group 6:59-65 Spiro [4.5] decane system 6:59 construction of 6:59 Spiro [5.4] indolenine system 11:329 Spiro [5.5] undecane group 6:59-65 construction of 6:59 Spiro [5.5] undecanone derivative 6:61 Spiro compound 16:46 Spiro isoxazole dematives 25:757 Spiro systems construction 6:60-65 by intermolecular cyclization 6:59 Spiroacetal subunits 12:27,28 White synthesis of 12:27,28 Spiroalkaloids 14:743-756 diastereomeric 14:743-756 from Nitraria schoberi 14:742 from Nitraria sibirica 14:742 Spiroalkyl analogs 28:357 biological activity of 28:357 of MFA 28:357 Spiroannelation 4:7,12;14:546 in bromochamigrene synthesis 6:60,61 of cyclohexanone aldehyde 6:61 of phenolic cx-diazoketone 6:60,61 Spirobenzoquinone furan unit 6:55 in stypolidione 6:55 synthesis of 6:55 Spirobenzylisoquinoline alkaloids 1:187-189 formation from 8,14cycloberbines 1:198-202
from 8-methoxyprotoberberinephenolbetaines 1:202-204 synthesis of 1:197-206 Spirobenzylisoquinolines 1:218,219 biogenesis of 1:218,219 Spirobncarbocyclic chamigranes 6:60 from Laurencia species 6:60 synthesis 6:59,60 Spirocyclic core 21:391 synthesis of 21:391 Spirocyclic systems 6:59-65,85 Spirocyclization 10:170;14:649,755; 16:28 enantioselective 14:750 Spiro-dehydration reaction 12:64 Spiro-diastereomers 8:382-384,386 Spiro-diterpenes 15:260-263 Spirodysin 21:310;25:692 Spirodysin intermediate 4:676 Spiroepoxynucleosides 4:252,257 synthesis of 4:252,257 Spiroethers 18:269-309 synthesis of 18:269-309 Spiro-indolenine derivatives 11:392395 Spiroiridal triterpenoid 28-deacetylbelamcandal 25:543 Spiro-isoquinoline derivative 6:496 of ring C-homoberberine analogue 6:496 Spiroketal enol ethers 7:220 Spiroketal reduction 18:276,277 with DIBAH 18:276,277 with Silane-Lewis acid 18:277,278 Spiroketals 9:530;13:60 diaxial configuration 1:476 stereoselective synthesis of 14:519-521 Spiroketone 8:288 from ketolactam 8:287 Spirolaurenone 6:64 from homogeranonitrile bromohydrin 6:64 relation to glanduliferol 6:63 synthesis of 6:64,65 Spiromentins B 29:300 synthesis of 29:300
742 Spiro-oxirane ring derivatives 23:605 13C-NMR data of 23:608 tH-NMR data of 23:608 of neo-clerodanes 23:605 Spiropentanopyrrolizine oxime 19:84,19:146 synthesis of 19:84,19:146 Spiroquinazoline 22:26 Spiro-rearrangement 12:99 Spirosolanes 7:17-22,24 Spirostane 21:643;25:55 Spirostane glycosides 17:136 Spirostane saponin 21:674 Spirostane-type saponin 21:675 Spirostanol 21:643 Spirostanol saponin 21:636,637 Spirovetivane 6:59 as sesquiterpene 6:59 Spirovetivane-type sesquiterpenes 14:546 enantioselective synthesis of 14:546 Spirulina platensis 25:725; 30:399,404,408 anti-influenza activity of 30:408 biological activity of 30:404 calcium spirulan from 30:399 polysaccharide (PS) from 30:408 Spizella arborea 5:837 hemoglobin components of 5:837 Spizella passerina 5:837 hemoglobin components of 5:837 Spleen/adipose tissue weight 30:56,57, 66 effect of fucoidan on 30:56,57 effect of oleic acid on 30:65 Splicing reaction 13:261,290 Spodoptera eridania 7:396;26:871 Spodoptera exigea 25:792 Spodopterafrugiperda 14:451 ;23:666 Spodoptera littoralis 18:772,20:245; 21:252,257,262,264,266,267,273,27 5 ;23:291,669,842 ;26:850,852854,869,870-872,874-876 Spodoptera litura 24:715,716;26:850 Spongia hispida 15:312
Spongia mycofijiensis 19:568; 25:896;28:710
Spongia nitens 17:10 Spongia officinalis 6:56,107,108;
17:10;25:688 Isoagatholactone from 6:56,107, 108 Spongia sp. 5:371;6:107,111;25:759 Spongia-13 (16), 14-dien- 19-oic acid 6:107,109 Spongia-13 (16),14-diene 6:107,109 (+)-Spongia-13 (16),14-diene 6:1112 synthesis of 6:116,118 Spongiacidin A 25:798,799 Spongiacidins A-D 25:711 Spongiadiol 6:107,109 epi-Spongiadiol 6:107,110 Spongian diterpenes 9:4 Spongian diterpenoids 1:662 synthesis of 1:662 Spongian-type diterpenes 6:107-132 stereoselective synthesis of 6:107-132 Spongiaquinone 15:298,318-321 Spongiaquinone potassium salt 15:298 Spongiatriol 6:107,109 epi-Spongiatriol 6:107,109 Spongiidae 6:107;19:568;25:688 Spongistatine 1 and 9 25:759,760 Spongistatins 25:757 Spongistatins 4 and 5 25:759 Spongosorites sp. 25:707,799 Spongouridin 5:403 Spontaneous apoptosis 26:926 Spontaneous metastasis 25:440 Sporangium cellulosum 26:450 Sporobolomyces odorus 13:309,312; 21:197 Sporobolomyces roseus 5:291 Sporobolomyces sp. 5:291 ;13:315 Sporogen-AO 1:697,698 synthesis of 1:697,698 Sporogen-AO 1 6:551-556 (+)-Sporogen-AO 1 6:553,554 synthesis of 6:553,554 Sporogenic substances 6:538-546 Sporogenesis 6:546 Sporomia fungi 15:384 6-methoxymellein from 15:384
743
Sporomiella australis 22:70 Sporomiella intermedia 22:70,253; 23:344
Sporothrix curviconia 5:304 Sporothrix flocculosa 21:189;22:74 Sporothrix inflata 5:304 Sporothrix rugulosa 22:74 Sporothrix schenckii 5:302-305,322,325 monohexosylceramides from 18:807 Sporothrix schenckii var. luriei 5:304 Sporothrix sp. 5:302,304,325,328 Sporotrichum dimorphosporum 8:349 xylanase A from 8:349 xylanase B from 8:349 Sporotrichum pulverulentum 26:1013 Sporotrichum thermophile 2:323 Sporulation 6:552 classification of fungi by 6:546 Sprekelia formosissima 20:356 S-Propyl cysteine (SPC) 23:458,468 S-Propyl-y-glutamylcysteine 23:458 Sputtering of ions (SIMS) 5:632 by bombardment with fast ions 5:632 Squalene 7:131;9:39;21:314 from presqualene diphosphate 7:325 Squalene biosynthesis 7:322 Squalene cyclization 1:655 Squalene oxide cyclase 14:740 Squalestatins 21:192;22:253,256 Squamocin 26:793,794 Squamone 9:398 Squarroside A 26:31,50 immuno-modulatory effect of 26:31 from Vaccaria segetalis 26:50 Squash family serine protease inhibitors 29:614 BD-TI-II as 29:614 CMTI-I as 29:614 CMTI-III as 29:614 CMTI-IV as 29:615 CPGTI-I as 29:615 CPTI-II as 29:615 CSTI-IIb as 29:614 Cucumis CMCTI-I as 29:614 Cucumis CMeTI-A as 29:614
CVTI- 1 as 29:614 Ecballium EETI-II as 29:615 effects on cathepsin G 29:615 effects on elastase 29:615 effects on endopeptidase 29:614 effects on factor Xa, factor XIIa, kallikrein, trypsin 29:615 effects on lysyl endopeptidase 29:614 effects on trypsin 29:614-616 effects on Xa, XIIa, kallikrein, plasmin, trypsin 29:614 ELTI-I as 29:615 from Bryonia dioica 29:614 from Citrullus vulgaris 29:614 from Cucumis melo 29:614 from Cucumis melo 29:614 from Cucumis sativus 29:614 from Cucurbita maxima 29:614 from Cucurbita pepo 29:615 from Ecballium elaterium 29:615 from Echinocystis lobata 29:615 from Lagenaria leucantha 29:615 from Luffa acutangula 29:615 from Luffa cylindrica 29:615 from Momordica charantia 29:615,616 from Momordica cochinchinensis 29:616 from Momordica repens (Cucurbitaceae) 29:616 from Tricosanthes 29:616 HMTI-I as 29:614 LATI as 29:615 LATI-II as 29:615 LLDTI-I as 29:615 LLDTI-II as 29:615 MCEI-I as 29:615 Squatene 22:253 Src homology domain 2 27:824 SRE oncogene 15:443 (+)-Srilankine 16:525-527 synthesis of 16:525-527 S-Solanidine 23:575 Stachenol 29:101 activity in EBV bioassay system 29:101
744
Stachenone 29:101 activity in EBV bioassay system 29:101 Stachybotrin A 22:72 Stachybotrin B 22:72 Stachybotrys sp. 9:203 ;21:233 Stachys chrysantha 30:270 xanthomicrol from 30:270 Stachys flavonoids 30:270-272 Stachytarpheta cayennenis 25:611,613; 28:400;29:84 n-Stacking model 4:609 Stagonospora genus 28:149 Standinger reaction 1:352,353 Standishinal 29:100 activity in EBV assay system 29:100 Standishinal diacetate 29:100 activity in EBV assay system 29:100 bis-Stannane 21:400 Stannoxane 1:274 Stanols 9:469,470 Stansioside 7:462,463 Stapfinine 5:125,172,173;9:172 Staphylococcal mammary infection 23:137 in ewes 23:137 Staphylococcus albus 22:398 Staphylococcus aureofaciens 28:135 as antibacterial agent 28:135 Staphylococcus aureus 3:302;5:368, 370;505,511 ;7:282,304,309;8:102; 9:308,500;10:117;12:401;13:162,164 ,173,181,183;17:285;18:777,778; 19:556,601,712;20:30,32;21:62,266, 599,600,601,602,604,615 ;22:627, 628,675;23:41,136,158,474,535; 25:253,257,259,260,271,765,770, 776-778,789,791,821 ;26:77,79,83, 227,330-333,402,673 ;29:269,324, 339;30:628,739 antibacterial activity against 30:739 antibacterial properties of 30:628 antifungal activity against 30:739 minimal inhibitory concentration (MIC) of 30:693
Staphylococcus botryosum 25:305 Staphylococcus citerus 9:308 Staphylococcus coli 23:533 Staphylococcus epidermidis 9:308;12:401 ;13:164,173 ;20:712;25: 776;26:402,1093,1095,1097,1098 minimal inhibitory concentration (MIC) of 30:693 Staphylococcus ganera 29:311 Staphylococcus haemolyticus 25:776 Staphylococcus hominis 25:258 Staphylococcus spp. 26:556 Staphyllococcus saprophyticus 30:693 minimal inhibitory concentration (MIC) of 30:693 Staphyllococcus warnieri 30:693 minimal inhibitory concentration (MIC) of 30:693 Starfish fertilisation inhibitor 28:712 callyspongin B as 28:712 Statil 22:172 Statine 10:260,261,263,266,267,272 diastereoselective synthesis of 12:479-481 from (R)-c~-hydroxy-13phenylpropionate 12:479 from methyl (R)-a-hydroxyphenyl propionate 12:480 synthesis of 12:477,480 (+)-Statine 12:430,431 mutual transformation of 12:430,431 with epistatine 12:430,431 (3S,4S)-Statine 12:476 synthesis of 13:513 (-)-Statine (3S,4S)-4-amino-3-hydroxy6-methylheptanic acid 12:432 biological activity of 12:432 from (4S,5 S)-allyl-4-methoxy-2oxazolidinone 12:432,433 synthesis of 12:432,433 Staurogyne merguensis Wall. 27:39,40 strogin 1 from 27:39,40 strogin 2 from 27:39,40 strogin 4 from 27:39,40 Staurosponine ("AM-2282") 12:365 from Streptomyces staurosporeus 12:365
745
Staurosporine 1:3,4;5:55-61 aglycone of 1:10,22;12:379-381 antibacterial activity of 12:384 biosynthesis of 12:373,374 dynamic NMR study of 12:367 from Streptomyces diastatochromogenes 12:366 from Streptomyces sp. C-71799 12:366 from Streptomyces sp. PK-286C 12:366 from Streptomyces staurosporeus 12:367 synthesis of 1:5,22 X-Ray crystal structure of 12:367 Staurosporine ("M-193") 12:365 from Streptomyces sp. M- 193 12:165 Staurosporine (NB-2025) 12:411 from Streptomyces actuosus 12:411 Staurosporine aglycone 5:55 ~H-NMR spectrum of 5:58 Staurosporinone (K-252c) 12:379-381 synthesis of 12:379-381 Stavudin 24:474,486,488 as anti-viral agent 24:474,486, 488 Steam distillation 21:575 Stearic acid 11:192;13:308; 21:189;25:333;26:461 ;30:65 biosynthesis of 11:192 from carp oil 30:65 in Penicillium brefeldianum 11:192 Steffimycin 4:350 Steganacin 5:461,462;26:196,216 (+)-Steganacin 29:382,384,392 steganes synthesis of 29:382, 384,388,392, (+)-/(-)-Steganacin 29:387 steganes synthesis of 29:387 Steganangin 26:216 Steganes 29:360 absolute configuration of 29:360 antitubulin activity of 29:399, 400 association with dibenzo-
cyclooactadiene lignans 29:360 asymmetric synthesis of 29:360 bulky sugar moiety in 29:401 demethylation of aryl methoxy groups in 29:401 microtubules assembly inhibition by 29:399 (-)-steganacin as 29:360 (-)-steganangin as 29:360 (-)-steganol as 29:360 (-)-steganone as 29:360 SAR of 29:399 structural variety of 29:360 tubulin assembly inhibition by 29:360 Steganes synthesis 29:369,380 by Brown and Robin 29:392 by Enders 29:389 by Kende 29:380,384 by Kende/Schlessinger 29:391 by Koga 29:386 by Krow 29:384 by Magnus 29:389,390 by Meyer 29:394 by Motherwell 29:399 by Raphael 29:382 by Schlessinger 29:384 by Suzuki-Miyaura 29:396 by Ziegler/Brown/Robin 29:391 cross-coupling reactions in 29:396 diastereoselective approach in 29:394,398 driving force for 29:381 from dibenzylbutyrolactone yatein 29:369,371 Grignard/oxazoline (Meyers) biaryl coupling in 29:394 intramolecular oxidative biaryl coupling in 29:384 isomerization studies of 29:380 matairesinol-type intermediate in 29:371 of (-)-isostegane 29:389 of (-)-steganone 29:393 of (-)-steganone by Molander 29:398 of (-)-steganone by Uemura 29:397
746
of (+)-yatein 29:388 of (+)-steganacin 29:382,384, 387,392 of (i)-steganone 29:382,390 of natural (-)-steganone 29:392 oxidative dimerization of coniferyl alcohol in 29:370 phenanthrene ring enlargement in 29:382 role of stegane diastereoisomers in 29:382 stereoconvergent type of 29:389 shikimic acid-cinnamic acid pathway in 29:369 Suzuki biaryl coupling in 29:396 Ullmann biaryl coupling in 29:391 use of vanadium in 29:391 weaknesses of 29:395 Stegangin 26:196,216 Steganoate B 26:216,217 Steganolide A 26:216,217 (-)-Steganone 24:780,781 of arylnaphthalene derivatives 24:788-789 of dibenzocycooctadiene derivatives 24:790-791 of dibenzylbutane derivative 24:781-784 of dibenzylbutyrolactone derivative 24:781-784 of 2,6-diaryl-3,7-dioxabicyclo [3.3.0]octanes 24:785-787 of tetrahydrofurans 24:785-787 transformations and interconversions 24:781-791 (+)-Steganone 29:382,390 steganes synthesis of 29:382,390 Steganotaenia araliacea 17:346; 26:216;29:360 episteganangin from 26:216 steganangin from 26:216 stegancin from 26:216 steganolide A from 26:216 steganoate B from 26:216 Stellaria media 24:273;25:781 Stellattamide B 27:251 from Korean sponge 27:251 Stellera chamaejasme 27:831
Stelleta globostellata 21:254,273 Stelleta sp. 21:269,273;25:700 Stelletamine 25:893,895 Stelletins A,B,C,D,E,F and G 21:273 Stellettamine 28:687 N-deacetylkuanoniamine C from 28:687 total synthesis of 28:687 Stellettanide A 25:705 Stellettanide B 25:705 Stellettazoles B 25:706 Stellettazoles C 25:706 Stelospongia conulata 15:312 Stemmadenine 1:49;26:139 conversion to condylocarpine derivatives 1:49 oxidative cyclization of 1:49 synthesis of 1:41,43-55 Stemmadenine derivative 6:520 Stemofoline 21:769 Stemonajaponica 21:759 Stemona mairei 21:759,764 Stemona parviflora 21:759,764 Stemona sessilifolia 21:759,764 Stemona tuberosa 21:752,760,764,769 Stemonidine 21:759,769 Stemonoporol 23:533;26:562 Stemonoporous canaliculatus 23:547 Stemotinine 21:759-762 Stemphylium botryosum 25:307 Stemphylium epidermidis 25:258,259 Stemphylium radicinum 19:154 Stemphylium solani 25:302,303,307 Stemphylium sonnei 25:260,305 Stenbergine 26:610,614 Stenodynerus floridans 5:223,253 Stenodynerus fulvipes 5:223,224, 232,253 Stenogramme interrupta 30:402 carrageenans from 30:402 Stenophyllol A&B 26:564 Stenotrophomonas maltophilia 28:140 Stentor coerulus 22:647 Stentorin 22:647 Stephania cepharantha 22:533 for epilepsy 22:533 Stephania erecta 20:522;29:578 Stephaniajaponica 6:480 protostephanine in 6:480
747
Stephania pierrei 20:522 Stephania tetrandra 22:69;24:895; 25:476;29:578 Stephania venosa 2:253 Stephanitis 26:443 Stephanotis lutchuensis Koidz. var. japonica 21:674,27:41 sitakisoside I-IV, XI-XIII from 27:41 sitakisoside XVI from 27:41 sitakisoside XVIII from 27:41 Stepharine 2:254,225 hydrogenation of 2:254,225 Steptocarpus dunnii 29:733 Steptonivicin 23:356 Steracaulon ramulosum 5:310,311 Sterculia lychophora 24:275 Sterculia urens Roxb. 30:405 antiviral activity of 30:405 Stereocaulon japonicum 5:310 Stereochemical control 29:422 of c~,c~'-disubstituted 3piperidinol alkaloids 29:422 Stereochemical inversion 6:178 Stereochemical revision 9:19 of methyl nuapapuanoate 9:19 Stereochemistry 8:296-298;30:502, 584,586,587 in Diels-Alder reaction 4:122, 123 of (7R,SS,7'R,8'R)-(+)-7'-acetyl5 '-methoxypicropodophyllin 30:586 of 3-carboxymuconate 8:296298 of acetylenic carotenoids 6:152138 of allenic carotenoids 6:135-138 of bicyclomycin 12:64 of C45 carotenoids 7:355-360 ofCs0 carotenoids 7:355-360 of carotenoid biosynthesis 7:317-367 of cis, cis-3-carboxymuconic acid 8:297 of cyclization 7:338-354 of cycloaddition 4:122,123 of (-)-hernone 30:587 of lithio dianion-imine
condensation 4:446,447 of (+)-malekulatine 30:584 of spiroethers 18:303-305 of trans BC-ring fusion 12:205 Stereochemistry of cycloaddition 4:122, 123 in Diels-Alder reaction 4:122, 123 Stereocontrol methods 1:578 Stereocontrolled approach 29:379 to allocolchicinoids total synthesis 29:379 Stereocontrolled 3yn aldol reaction 13:546 Stereocontrolled synthesis 28:358 of (+)-paraherquamide B 28:358 Stereodifferentiating reactions 16:399 using chiral auxiliaries 4:327345 Stereodivergent process 29:419 decahydroquinoline-type dartpoison frog synthesis by 29:419 iso-6-cassine synthesis by 29:419 3-piperidinol alkaloids synthesis by 29:419 prosafrinine synthesis by 29:419 prosophylline synthesis by 29:419 prosopinine synthesis by 29:419 Stereogenic center 22:236 Stereogenicity 7:5 Stereoisomeric alkaloids 21:759 Stereoisomeric mixtures 6:152 Stereoisomers 17:483;30:145 of fucoxanthin 6:139 of neoxanthin 6:139 of peridinin 6:139 of triene 30:145 Stereomutation mixture 6:139-141 iodine catalyzed 6:139-141 Stereomutation studies 6:154 of acetylenic carotenoids 6:154 of diacetylenic alloxanthin 6:153 of monoacetylenic-7,8didehydroastaxanthin 6:153 of tetradehydroastaxanthin 6:153
748
Stereoselective 24:3,12,15,27-34,45,46, 70-72,742,745,746,759,760,763-765, 773,774,777,778 alkylation 24:12 conjugate addition 24:15 coupling 24:742,745,746,759, 760,763-765 dienone-phenol rearrangement 24:777,778 epoxidation 24:3,27-34,45,46 a-hydroxylation 24:70-72 Mukaiyama reaction 24:773,774 offl-keto ester 24:759,760 ortho-ester Claisen rearrangement 24:3 radical carbocyclization 24:3 reduction 24:745,746,759,760, 763,765 Stereoselective addition 19:33 in D-glycero-D-galactoheptose synthesis 4:198,199 Stereoselective aldol condensation 6:264,268 Stereoselective arylation 10:345 C-glycosidation 10:345 Stereoselective C-glycosylations 10:373 Stereoselective construction 19:470 of withanolide D-type side chain 19:470 Stereoselective epoxidation 4:505; 6:553,554;11:165,166,172;14:366 of tetracyclic intermediates 14:148-150 Stereoselective glycosidation 8:359 Stereoselective hydrogenation 10:551, 552 Stereoselective intramolecular reductive alkylation 10:541 Stereoselective ketone reduction 13:600 Stereoselective Michael addiction 13:619 Stereoselective pinacol-type rearrangement 15:509 Stereoselective reduction 10:537;11:91, 99,100,103,104,170-172;12:337; 14:72,378,529 by 1,3-asymmetric induction double bond hydrogenation 14:147
of azetidinone 4:437 of brasilenone 6:7,8 of chiral [3-keto sulfoxide 14:529 ofpenicillinates 4:437 of [3-ketoester 6:429,430 with diisopropylamine borane 4:437 withDipodascus sp. 12:337 with K-Selectride 4:437 with NaBH4 CeC13 3:483-485 with tetrabutylammonium borohydride 3:483-485 Stereoselective ring opening 12:346 Stereoselective synthesis 6:5-38,54;8:9; 12:353,354,467,468;15:243 ;18:193227 of (+)-dolasta-1 (15),8-dien-14 [3-ol 6:54 of (+)-eremophilone 15:243 of (-)-swainsonine 12:330 of (+)-castanospermine 12:353, 354 of cis cyclopentane 8:9 of 3,7-octadien-l-ol- 12:467,468 of acetogenins 18:193-227 of bicarbocyclic fused systems 6:5-38 of carbonolides 11:163-172 of cis-2,6-dialkylpiperidines 6:431,432 of doxorubicin 14:3-46 of forsythide aglycone dimethyl ester 16:294 of leuconolides 11:163-172 of maridonolides 11:163-172 of methyl cyclopentanoid monoterpenes 20:41-46 of natural products 12:445-498 of oligonucleotides 13:275-281 of spiroketals 14:519-521 of tetraponerine-8 6:452 of threo-2-amino alcohols 12:489-493 of trans-2,6-dialkylpiperidines 6:431,432 of vitamin D 10:43-75 of [3-oxygenated y-amino acids 12:476-489
749 of E-retinal 28:74 of diterpenes bioactive 29:169 oftrans cyclopentane 8:9 Stereoselective Wittig reaction 12:312 Stereoselective a-hydroxylation 9:518 ~-Stereoselectivity 10:466 Stereoselectivity 4:161,162,167,168, 170-172,175,178,183,188;12:452 of oxazolo [4,3-a] isoquinolines 12:452 of (Z)-conjugate esters 4:177,178 of C(3)-monosubstitution reactions 4:653 of (E)-nonenopyranuronate 4:180,181 of osmylation 4:161,162,167, 168,170-172,175,178,183,188 of Wittig reaction 4:175 endo-Stereoselectivity 4:657,659 Stereospecific- 11:98;12:298 cyclization 12:298 reduction 11:98 Stereospecific cationic cyclization 12:456 Stereospecific deuteration 20:839 Stereospecific hydroxylation 1:404,405 Stereospecific intramolecular-DielsAlder cycloaddition 6:86,87 in 7,20-diisocyanoadociane synthesis 6:86,87 Stereospecific oxidation/reduction 17:484 Stereospecific preparation 12:466,467 of (3E)-3,7-octadien- 1-ol 12:466,467 of 6-oxygenated 4otaryldecahydroisoquinolines 12:457,458 Stereospecific reduction 4:234 ofketonucleosides 4:234 Stereospecific synthesis 18:197-202 Stereospecific c~-glycosylation 30:459 Stereospecificity 14:201-259 of glycosylation reactions 14:201-259 Stereum purpureum 26:133 Steric effect 27:355 of benzene ring 27:355
Sterllaria dichotoma 26:41 Steroid alkaloid glycosides 24:132,133 Steroid glycoside 24:132 Steroid hormones 13:634;27:823 Steroid intermediate 4:674,675 Steroid moiety 30:486 acetylation of 30:486 deoxygenation of 30:486 iodonization of 30:486 LiA1H4 reduction of 30:486 ozonolysis of 30:486 synthesis of 30:486,487 Steroid saponins 7:426;15:27-29 molluscicidal activity of 7:427 Steroidal alkaloids 2:175-207;21:73, 79,80,84,109;23:575 from Veratrum califorincum 7:16 from Solanum umbelliferum 20:489 teratogenic potencies of 23:575 Steroidal amines 7:16-24 teratogenic metabolites of 7:2124 toxic 7:16-24 Steroidal estrogens 5:448 Steroidal glycoalkaloid 25:293,295,297, 302,303 Steroidal glycosides 7:286,303 substrates 17:483 Steroidal ketones 5:698-701 Steroidal lactones 14:439;20:135-148 cardiac active steroids 14:439 from Digitalis putpurea 14:439 Steroidal type solanaceae alkaloids 11:229 Steroid-alkaloid glycoside 5:110 Steroid-pyrazine 18:875-905 via c~-amino ketones 18:885-887 Steroids 21:451,459;23:637;24:10281033,1034,1081,1082 as antiviral compound 24:510521,533-540 of marine fungi 24:1028,1034, 1081 Steroids C-27 5:46 synthesis of 8:188-195 semi-synthesis of 17:622-631
750
Sterol biosynthesis 25:303 inhibitor of 25:303 Sterol sulfate (6(x-) 28:702 cytotoxicity against 28:702 Sterol sulfates 21:314 Sterols 5:17:78-79,153,207,403,405; 474 ;23:168;24:799;25:43 antitumor activity of 25:43 antiinflammatory activity of 25:43 from olive oil 27:702 Sterulic acid 9:38,44,45 biosynthesis of 9:45 Steryl esters 9:457-486 catalytic deuteration of 9:476 chromatographic analysis of 9:457-486 extraction of 9:449,450 HPLC analysis of 9:460-464 LC/MS of 9:476-478 mass spectrometric analysis of 9:447-486 Steryl ferulates 9:473,474 Steryl palmitates 9:454 of 5(x/5[3-cholestanol 9:454 of cholesterol 9:454 Steryl xylosides 7:282 Stetter thiazolium salt method 6:437438 Stevens [ 1,2]-sigmatropic rearrangement 6:315 Stevens and Bisacchi synthesis 14:684686 of taxodione 14:684-686 Stevens condensation 3:463 Stevens rearrangement 6:497;16:470471 of ring C-homoberberine analogue 6:496 Stevia 27:299-317 acute toxicity tests of 27:307 allergenic activity of 27:315 as sweetener 27:299-317 bioavailability of nutrients 27:312-314 chronic toxicity studies of 27:306-308 effect on fertility 27:309,310 for diabetics 27:314
for stevioside 27:307,310 immunological activity of 27:315 nutritional significance of 27:314,315 safety evaluation of 27:299-317 subacute toxicity studies of 27:307,308 Stevia extract 27:307,310,314 for diabetics 27:314 Stevia leaves 27:315 immunological activity of 27:315 Stevia phlebophylla 15:16 Stevia plant 27:315 allergenic activity of 27:315 Stevia purpurea 8:44-46 1-bisasolones from 8:44-46 Stevia rebaudiana 15:4,5;27:8,9,13, 22,299,311 ;29:101 ent-kaurene from 27:22 labdane glycosides from 27:22 of asteraceae 27:299 rebaudioside A from 27:8,9,13 rebaudioside B from 27:13 rebaudioside C from 27:13 rebaudioside D from 27:13 rebaudioside E from 27:13 stevia extract from 27:8 steviolbioside from 27:13 stevioside from 27:8 sugar-transferred Stevia extract of 27:8 Stevia selriana 25:251 Steviol 27:304,305,307,312 acute toxicity tests of 27:307 effect on fertility 27:312 mutagenicity tests with 27:304 Steviol 13-O-[3-D-glucoside 15:18 27:13,22,23 structure of 27:23 Steviol epoxide 27:302 Steviolbioside 27:13,23,300 strucutre of 27:23 Steviolmonoside 15:18 Stevioside 31715:16;27:8,9,13,22,299317;29:101 activity in TPA bioassaysystem 29:101
751
activity in skin-1 bioassay system 29:101 acute toxicity tests of 27:307 allergenicity problems of 27:315 as sweetner 27:299-317 chronic toxicity studies of 27:306,307,308 effect on fertility 27:309,310 for phenylketonuria 27:315 mutagenicity tests for 27:303,304 nutritional significance of 27:314,315 purity of 27:316,317 structure of 27:300 subacute toxicity studies of 27:307,308 Stichlorogenol 7:272 Stichloroside A~ 7:272,274;15:87 Stichloroside A2 7:272,274;15:87 Stichloroside B~ 7:272,274;15:87 Stichloroside B2 7:272,274;15:87 Stichloroside Ct 7:272-274;15:87 Stichloroside C2 7:272-274;15:87 from Stichopus chloronotus 15:87 Stichococcus bacillaris 26:358 Stichopodiadae 7:272-274,282 Stichoposide A 7:272-274,282 Stichoposide B 7:272-274 Stichoposide D 7:273 from Stichopus variegatus 7:273 Stichopus chloronotus 7:272; 15:87;28:593 stichlorosides A1, B~, C~ and A2, B2, C2 from 15:87 Stichopus japonicus 7:277 holotoxins A, A~, B and B~ 15:87 Stichopus sp. 7:282 Stichopus variegatus 7:272,282 stichoposide D from 7:273 Stictanin 9:186 Sticticine 9:190,192 Stigmast-4-ene-3-one 20:702 from Salvia nemorosa 20:702 Stigmast-7-ene-3-ol 20:702 from Salvia nemorosa 20:702
Stigmast-7-ene-3-one 20:702 from Salvia nemorosa 20:702 Stigmastane 25:49 Stigmastanyl ferulate 9:454 Stigmasterol 2:129;9:284,295;7:124; 18:515 ;! 6:323 ;22:482;25:61 ;30:208, 505,570,719 analgesic effect of 30:208 from Salvia glutinosa 20:707 from Salvia limbata 20:702 Stigmasterol [(24S)-24-ethyl-cholest5,22-dien-3 ~-ol] 9:447,454,455 Stigmasteryl-[3-D-glucopyranoside 7:190 Stigosine 1:260 Stilbella sp. 21:224 trans-Stilbene 11:423,424 pallescensin-E from 6:31 (E)-Stilbene 20:302 Stilbene 5:467;9:391;22:609, 611;23:342 oxidation of 30:222 Stilbene derivatives 27:405,409;28:579 biological activity of 27:405,409 2,3,5,4'-tetrahydroxystilbene-2O-D-glucoside as 28:579 in LLC-bearing mice 28:579 piceid as 28:579 resveratrol as 28:579 tumor growth inhibition by 28:579 Stilbene dimer 9:258-263 from Gnetumla 9:258 Stilbene estrogens 5:453 Stilbene oligomers 27:767 Stilbene phytoalexin 25:662 Stilbene synthase 25:502,655 Still olefination 10:157;12:46,47 Still procedure 13:88 Still rearrangement 13:22 Still synthesis 6:47,542;10:18 of (+)-A9(12)-capnellene 6:47 of asperdiol 10:18 Stille reaction 26:1236 Stille-type Pd (0) catalysis 16:435 Stillingia lineata 7:417 Stimasteme 9:288,289
752
Stimulant agent 23:642 of teucrium sp. 23:642 Stimulatory 24:845 biological activity 24:845 Stimulus-response mechanisms 25:515 Stipitatic acid 1:340,341 synthesis of 1:340,341 Stiretrus anchorago 26:66 Stizolobic acid 21:70 Stoichactis helianthus 26:11 Stomoxys calcitrans 26:691 Stomphia coccinea 15:66;28:717 benzyltetrahydroisoquinoline imbricatine from 28:717 Stongylocentrotus purpuratus 9:575 Stork modification 10:185 of Michael addition 10:185 Stork-Boeckmann enone 12:262 Stork's vinyl radical cyclization 12:15 Stomiamide A 23:252 Stomiamide B 23:252 Stomiamide D 23:252 Stowell's iodide 8:146,147 S-Transferase (GST) 23:470 Stratospheric ozone concantractions 25:663 Strawberry anthocyanins 23:751 HPLC chromatogram of 23:751 Streblus asper 26:467 Strecker reaction 6:312 intramolecular 19:36 Strecker-type reaction 10:463 Strellidimine 6:516,519 biogenesis of 6:516,519 from Strychnos dinklagei 6:516 spectral data of 6:516,518 synthesis of 6:516,517,519,520 Strempeliopine 9:186 Strenbergia lutea 26:609-612,614,615 Streotpmyces lysosuperficus 1:417 Strepromyces albolongus 23:61 Streptal 14:102 Streptavidin 18:919 (+)-Streptazolin 13:514,515 Overman synthesis of 13:514,515 Streptococci 29:535 classification of 29:535 identification of 29:535
pathogenicity of 29:535 serological groups of 29:535 Streptococci 29:535 pathogenicity of 29:535 serological groups of 29:535 Streptococcus bovis 19:696 Streptococcus durans 25:259 Streptococcus faecalis 4:432,12:103, 401 ;19:696;25:259,260;26:77,83 Streptococcus fecalis var. liquifaciens 25:923 Streptococcus fecium 25:925 Streptococcus ganera 29:311 Streptococcus haemolyticus 26:673 Streptococcus mutans 7:69;18:673, 20:32,34,36;23:536;26:64,226,227; 27:778 Streptococcus pneumoniae 14:233; 25:780;26:1154 capsular polysaccharide 14:233 Streptococcus pyogenes 5:601,9:308; 10:117;13:162,173,181,183;19:492; 25:452,776
Streptococcus pyogenes haemolyticus 29:324
Streptococcus salivarius 26:402 Streptococcus sanguis 7:69;26:402 dextransucrase from 7:41
Streptococcus sobrinus 27:316,778 Streptococcus sp. 5:325;16:108; 21:615;25:257;26:1145;29:230 Streptokinase (SK) 30:839,844 fibrinolytic enzymes 30:839 Streptokinase/streptodornase 25:271 Streptolic acetate 14:104 Streptolic acid 14:102,104 (+)-Streptolic acid 14:112-114 synthesis of 14:112-114 Streptolydigin 14:97,98,100,101 Streptolydigin phosphonate tetramic acid 14:117,118,132-134 synthesis of 14:117,118,132-134 Streptolygidin 28:130 antibiotic activity of 28:130 as bacterial RNA polymerase inhibitor 28:130 as terminal DNA transferase inhibitor 28:130 Streptomyccs griseus SS-20 24:937
753
Streptomyce lividans 26:1010 Streptomyces achromogenes 23:68,88 Streptomyces actuosus 12:365;21:399 staurosporin (NB-2025) from 12:365 alisamycin from 21:399 Streptomyces aizunensis 12:63 aizumycin from 12:63 Streptomyces albus 21:420 porothramycin A from 21:420 Streptomyces aldus 25:781 Streptomyces althioticus 28:143 Streptomyces amakusaensis 19:178 Streptomyces ambofaciens 5:613,614 Streptomyces antibioticus 11:214,215; 21:303 ;26:1010;29:319 chlorothricin producer 11:214,215 Streptomyces arenae 29:319 Streptomyces aureofaciens 21:414; 29:312 Streptomyces aureus 5:429,434 Streptomyces avermitilis 1:435;28:396 avermectins from 12:3 Streptomyces azureus 11:209 thiostrepton from 11:209 Streptomyces bikiniensis 18:700 Streptomyces cacaoi 23:343 Streptomyces cacaoi var. asoensis 1:399 Streptomyces caespitosus 9:431 ;13:434 albomitomycin A from 13:433 isomitomycin A from 13:433 mitomycins A-C from 13:433 Streptomyces cattleya 11:210; 12:145;29:343 thienamycin from 11:210;12:145 Streptomyces cellulosae 12:103,54; 21:197 Streptomyces chrysomallus 8:102; 26:1010 Streptomyces cinnamonensis 11:197 Streptomyces clavuligerus 22:263 Streptomyces coelicolor 5:617,618; 22:263,265 Streptomyces collinus 11:189191 ;23:65,66;29:322 ansatrienin (mycotrienin) from 11:189
enoyl CoA reductase from 11:190-191 Streptomyces curacoi 29:325
Streptomyces diastatochromogenes 12:366 staurosporine from 12:366 Streptomyces distallicus 5:551 Streptomyces erythreus 13:166;25:780 Streptomyces exfoliatus 23:343 Streptomyces flaveolus 14:97,98; 21:412; 28:131 tirandamycin A from 14:98 tirandamycin B from 14:97,98; 21:412 Streptomyces flavogriseus 10:103 Streptomycesfradiae 5:591 ;29:329 urdamycin from 11:134 Streptomyces fungicidus 29:332 Streptomyces genus 29:321 Streptomyces globisporus 29:326 Streptomyces gougerotti 4:242 Streptomyces graminofaciens 29:326
Streptomyces griseochromogenes 4:242;18:269;28:127
Streptomyces griseoflavus 12:63; 19:165,167,177 ;21:403 colabomycin A from 21:403
Streptomyces griseolavendus 15:445;27:869
Streptomyces griseolus 1:408;26:830 Streptomyces griseoplanus 10:104 Streptomyces griseoru-biginosus 21:405 Streptomyces griseoviridis 26:444; 29:320
Streptomyces griseus 1:514;7:388; 18:700;19:587 ;21:304 ;22:80;23:474; 29:611 actinophage B 1 from 21:408 aplasmomycin from 21:304 Streptomyces griseus var. autrophicus 26:454,1123,1155 Streptomyces grisline 12:300 indolizomycin from 12:300 Streptomyces hagronensis 21:401 U-56407 from 21:401 Streptomyces hydroscopicus 21:388; 23:72;29:332 Streptomyces hygroscopicus ssp limoneus 13:223
754
Streptomyces hygroscopicus var. geldanus 21:437 Streptomyces hygroscopicus var. Limoneus 29:480 Streptomyces incarnatus 19:177;26:830 Streptomyces kasugaensis 23:343 Streptomyces lavendulae 10:7780;21:266;25:825 ;29:332
Streptomyces lusitanus 10:103 Streptomyces lydicus 14:105; 21:411;28:126;130 streptolydigin from 14:97,98,100 Streptomyces malachitofuscus 29:317 Streptomyces matensis 11:113;28:143 vineomycin A l from 11:113 Streptomyces matensis ssp. vineus 5:594 Streptomyces mediocidicum 11:278 telocidines from 11:278
Streptomyces melanovinaceus 10:115,19 :289,340
Streptomyces miharaensis 1:404 Streptomyces mobaraensis 15:457 Streptomyces morookaensis 4:242 Streptomyces nigellus 23:61 Streptomyces nitrosporeus 29:339 Streptomyces noboritoensis 5:590 Streptomyces nodosus 4:513; 23:343,347 amphotericin B from 6:261 Streptomyces nodosus var. asukaensis 11:189;21:401 asukamycin from 11:189 Streptomyces nogalater 14:47 nogalamycin from 14:47 Streptomyces nourcei 22:58,80 Streptomyces novoguineensis 1:404; 22:273 Streptomyces OM-4842 5:597 Streptomyces orientalis 21:406 reductomycin from 21:405 Streptomyces oxamicetus 4:234 Streptomyces pactum 15:457 Streptomyces parvulus 21:403;28:135 manumycin A from 21:403 manumycin D from 21:403 Streptomyces phaechromogenes var. ikaruganensin 28:138
Streptomyces phaeochromogenes 5:553; 18:10
Streptomyces plicatus 4:243,244 Streptomyces primprina 22:533 Streptomyces pulveraceus sp. 27:883 Streptomyces purpeofuscus 26:373 Streptomyces pyogenes 29:536 Streptomyces ramulosus 10:443 (-)-acetomycin from 10:443
Streptomyces refuineus 21:420
anthramycin from 21:420
Streptomyces rhishiriensis 11:189 ansatrienin (mycotrienin) from 11:189 Streptomyces rimosus 11:135; 23:24,42,45 tetrangomycin from 11 : 135 tetrangulol from 11:135 Streptomyces rimosus var. paromomycinus 28:118 Streptomyces riseochromogenes 23:343 Streptomyces rishiriensis 23:75 Streptomyces rosa var. 0S-3966 11:127 Streptomyces roseopalvus 22:263 Streptomyces rugosporus 29:339 Streptomyces sandaenis 13:434 Streptomyces sapporonensis 12:63 bicyclomycin from 12:63 Streptomyces setonii 22:273,275 Streptomyces showdoensis 29:265 Streptomyces sp. M-193 12:365 Streptomyces sp. N-126 12:366,368 Streptomyces sp. PK-286C 12:366 staurosporine from 12:366 Streptomyces sp. RK-286 12:366 RK-286 C from 12:366 Streptomyces spectabilicus 20:796 Streptomyces spectabilis 21:430;23:3 streptovaricins A-G from 21:430 Streptomyces spiroverticillatus 18:269; 27:879 tautomycin from 18:269
Streptomyces spiroverticillatus Streptomyces staurosporeus 1:3;5:55; 21:262
Streptomyces strain 21:414,437; 28:138;29:328
Streptomyces subflavus ssp. irumaensis 5:597
755
Streptomyces tanashiensis 5:618 Streptomyces teryimanensis 12:300 indolizomycin from 12:300
Streptomyces thiolutens 21:420
mazethramycin A from 21:420
Streptomyces tirandis 3:270;
21:411;28:131 tirandalydigin from 14:97,98 tirandamycin A from 14:98;21:411 Streptomyces tolypophorus 23:56 Streptomyces toyocaensis 26:493 Streptomyces venezuelae 5:552;29:309 Streptomyces verticillatus 9:433-434 Streptomyces violaceoruber 4:255; 11:214,215 ;29:317 as granaticin producer 11:214,215 Streptomyces virginiae 29:332
Streptomyces viridochromogenes 29:325
Streptomyces viridosporus 15:441 Streptomyces xanthochromogenus 21:405 reductomycin from 21:405 Streptomyces xanthocidicus 29:328 Streptomyces zelensis 1:180;3:310 Streptomycetes 29:477 Streptomycin sp. 21:410 Streptopelia chinensis suratensis 5:837 hemoglobin components of 5:837 Streptopelia orientalis 5:837 hemoglobin components of 5:837 Streptopyrone 22:471 Streptosporagium sibiricum 26:1211 Streptovaricin 23:54 Streptovaricin A 21:430,431 ;23:64 Streptovaricin B 23:64 Streptovaricin C 23:64,65,79 ansa moieties 23:86 ~3C-NMR spectrum of 23:64 conversion of 23:65 Streptovaricin D 21:432,435;23:64 biosynthesis of 23:64 ~3C-NMR spectroscopy of 23:6 Streptovaricin E 23:64 Streptovaricin F 23:64
Streptovaricin Fc 23:65 Streptovaricin G 23:64 Streptovaricin J 23:64 Streptovaricin U 21:430;23:65 Streptovaricins 21:420,430,434;23:60 Streptoverticilium rimofaciens B98891 4:245 Streptoverticillium ardum 13:433 porfiromycin from 13:433 Streptoverticillium fervens 21:395 FR-900848 from 21:395
Streptoverticillium mobaraense 12:366,370 BE-13793 C from 12:366,370 Streptoverticillium olivoreticuli 22:533 Streptoverticillium olivoreticuli ssp. neoenacticus 10:638 Streptoverticillium verticillus 19:351 Strictalamine 5:155,154 Strictaminolamine 5:157,158 Strictanes 22:95 Strictanine 5:167 Stricticine 5:176 Strictine 5:153 Strictosamide 26:115,127 Strictosidine 1:89-91;2:376;15:486; 26:114-116,127,128,130,131,135 biosynthesis of indole alkaloids 1:90,91 dehydrogeissoschizine from 15:487,488 3~-H Strictosidine 26:97 Strictosidine lactam 2:375 Strictosidine synthase 13:662;27:781 from secologanin 27:781 from tryptamine 27:781 from strictosidine 27:781 Striga asiatica 5:823;9:364;30:162 infection with 30:162 Strobilurin A 22:249 Strobilurins 22:247,249 Strobilurus tenacellus 22:249 Strogin 1 27:2,39,40 structure of 27:40 Stromelsin m-RNA 12:398 Stronglyocentrotus purpuratus 25:813 Stronglyophora hartmani 15:312 Strongylin-A 15:300
756
Strongylocentrotus droebachiensis 7:285;15:104 Strongylocentrotus intermedius 7:285 sulfated sterols from 7:285 Strongylocentrotus nudus 25:788 Stro ngylocentro tus purpuratus 15:104;28:717 Strongyloides ratti 26:486 Strongyloides stercolaris 26:486 Strongylophora 25:690 Strongylophora durissima 21:275 strongylophorimis from 21:275 Strongylophora sp. 21:254. meroditerpenoids from 21:254 Strongylophorine dimer 21:285 Strongylophorine meroditerpenes 21:275 Strongylophorine-2 21:275 Strongylophorine-3 21:275 Strongylophorine-4 21:275 Strongylostatin 7:1,2,285 Strphanthus gratus 25:537 Structural elucidation 28:601 of sea cucumber triterpene glycosides 28:601 Structural studies 15:392-408 of xenocoumacins 15:392-408 Structural-functional activity relationship 23:108 Structure 27:323,438,423,501,677,758, 761,762,823 ;30:64,197,202,369,485, 571-580 of 1ot,25-dihydroxyvitamin D 30:485 of 1(x-hydroxyvitamin D analogues 30:485 of 2-phenyl-4H- 1-benzopyran-4one 27:841 of 5-hydroxytryptamine 30:370 of 5-hydroxytryptophan 30:369,370 of 9-nor-9 [3-OH-hexahydrocannobinol (HHC) 30:196 of achillamide 27:480 of acylated flavonoid glycosides 27:501 of aminoalkylindoles 30:196
of anandamide endocannabinoids 30:196 of astragaluquinone 27:500 of black sugar-1 27:412 of cannabinoid receptor ligands 30:197 of capsaicin 30:202 of capsazepine 30:202 of CP-55 30:940 of diarylpyrazoles 30:196 of eucryphin 27:397 of flavonoid 27:484 of ganoderic acid F 30:63 of monoterpenoid indole alkaloids 27:781 of nitrocompounds 27:532 of olvanil 30:202 of sandrosaponin 27:674 ofsandrosaponin III 27:674 of saponins 27:677 of tea saponins 27:402 of tryptophan 30:369 of A9- tetrahydrocannabinol (THC) 30:197 Structure activity relationship 20:791798;21:21,262,284,578,661,665,666 in acronycine 20:791-798 ofbioactive metabolites 21:251 of microcystins 20:897-899 ofnodularins 20:897-899 of scopadulan-type diterpenoids 21:717 Structure activity relationship studies (SAR) 30:195,494,800 of anandamide 30:196 of aspirin 30:195 ofopioid analogues 30:800 of vitamin D analogues 30:493 Structure confirmation 6:406 of peptidoglycan-related compounds 6:406 ofperforene 6:30,31 Structure dereplication 29:658 bioactive natural product database in 29:670 challenges in 29:671 data collection in 29:658 DEREP databases in 29:670 fraction splitting in 29:658
757 general aspect of 29:658 hardware selection in 29:658 (HPLC-ESI-MS) in 29:659 LC/MS/MS for 29:658 LC/NMR for 29:658 LC/PDA for 29:658 molecular ion profile of 29:659 natural products information system (NAPIS) in 29:671 of active crude extracts 29:659 of HTP fraction library 29:664 of novel chemical entities 29:658 protocol development in 29:658 Structure determination 6:135,138; 23:436 of allenic carotenoids 6:135-138 of oligomeric hydrolyzable tannins 23:436 Structure elucidation 15:187-224; 26:535-551 ;27:467,667 by MS, IR, NMR spectroscopy 27:659 of abscisic acid 6:559 of pironetin 30:26 of ptaquiloside 26:708 of reseveratrol oligomers 26:535-551 of saponins 15:187-224;27:667 of sclerosporin 6:546-556 Structure identification 27:240-247 of (-)-myrmicarin 27:240-247 of (+)-myrmicarin 27:240-247 Structure modification 6:405 in MurNAc 6:405 Structure-activity profile 12:220,221 oftaxol 12:220,221 Structure-activity relationship 23:154; 27:893,923 ;28:404 of eugenol 28:404 of flavanoids 27:923 Structure-antioxidant activity relationship 23:773 Structure-based inhibitor modeling 30:832 of (EFEa) 30:832 Structure-function relationship 21:21, 50,84 Structure-odour relationship 27:378 Structure-terata correlations 23:572
Strurnus vulgaris 5:836 hemoglobin components of 5:836 Strychnane alkaloids 6:520 Strychnan-type alkaloids 5:71,85,174180 Strychnine 1:74,75;7:444;9:186-188; 21:98;22:9,18,25,508,530;26:868 as immunosuppressive drug 25:530 Strychnine N-oxide 26:1049 Strychnobrasiline 26:1050,1054,1055, 1058,1063 Strychnochromine 9:183 Strychnofendlerine 26:1063,1064,1065, Strychnofluorine 1:38 Strychnopentamine 26:1062 anticancer activity of 26:1060 Strychnopivotine 1:38,39 Strychnos 6:503;26:1030-1032,1035 Strychnos alkaloids 16:435;26:10291031,1040,1049,1053,1054,1060, 1063-1065,1067 Strychnos atlantica 26:1050 Strychnos bifurcata 26:1034,1039 Strychnos bisindole 26:1062 anticancer activity of 26:1060 Strychnos camptoneura 26:1060 Strychnos cinnamomifolia 22:533 for epilepsy 22:533 Strychnos colubrina 26:1029 Strychnos decussata 26:1032,1035,1036 Strychnos dinklagei 6:503-536 alkaloids of 6:503-506 brafouedine from 6:503-506 cantleyine from 6:503-506 dinklageine from 6:522 ellipticine from 6:506 gentianine from 6:529 10-hydroxyellipticine from 6:509 18-hydroxyellipticine from 6:513 isobrafouedine from 6:503-506 8-methoxy-8,10-dihydrogentianine from 6:529 7-O-[4-methyl-5-(1-hydroxyethyl) nicotinoyl] strychnovoline from 6:522,527
758
monoterpene alkaloids from 6:522-527 oxidizing enzymes in 6:520 N-b-oxy- 17-oxoellipticine from 6:513,515 strellidimine from 6:516 venoterpine from 6:527 Strychnos diplotricha 26:1034,1038 Strychnos divaricans 26:1055 Strychnos floribunda 26:1032 Strychnos grossweilleri 1:125;26:1060 Strychnos guianensis 26:1055 Strychnos henningsii 26:1032, 1039,1035 Strychnos longicaudata 1:124 Strychnos madagascariensis 26:1033, 1035 Strychnos melinoniana 1:124,125 Strychnos mitis 26:1033 Strychnos monoindole 26:1061 anticancer/antiprotozoal 26:1061 Strychnos mostueoides 26:1034,1035 Strychnos myrtoides 26:1034,1035, 1038,1039,1050,1053,1065 Strychnos ngouniensis 1:124 Strychnos nux vomica L. 26:143, 1029;27:780 cantleyine from 6:503 Strychnos panganensis 26:1033, 1052,055 Strychnos pentantha 26:1034,1039 Strychnos potatorum 26:1031, 1032,1036 Strychnos sp. 26:1032-1034 alkaloid of 26:1032-1034 Strychnos spinosa 26:1033 Strychnos toxifera 26:143 Strychnos trichoneura 26:1034 Strychnos usambarensis 1:124,126; 26:1060,1063 Strychnos vacacoua 6:503 bakankoside from 6:503 Strychnos vomica 26:1052 Strychnospermine 26:1064,1065,1066 Strychnovoline 6:523,524 from loganin 6:523,524 from Scaevola racemigera 6:522 from Strychnos dinklagei 6:522
spectral data of 6:524,526 synthesis of 6:523,524 Strychnoxanthine 1:125;26:1060 Strychnozairine 1:38,39;9:186 Stryhcynan-type alkaloids 1:31,32 biosynthesis of 1:31,32 Stubenrauch's technique 4:414 Stubomycin 23:51 Sturmus pagodarun 5:837 hemoglobin components of 5:836 Styelid ascidians 23:241 Stylissa carteri 25:712,791 Stylocheilus longicauda 17:4,104; 19:549 Stylophora pistillata 28:646 palythrine-threonine- sulfate from 28:646 Stylophorum diphyllum 27:159 Stylophorum genera 27:163 Stylophorum lasiocarpum 27:159 (S)-Stylopine 14:771 biosynthesis of 14:771 from (S)-reticuline 14:771 Stylopine 21:57
Stylopus australis 28:704 Stylosanthes hamata 28:399 against Boophilus microplus 28:399
Stylosanthes humilis 28:399 against Boophilus microplus 28:399
Stylosanthes scabra 28:400 Stylosanthes sp. 400 Stylotella agminata 25:770 Stylotella aurantium 21:351,356,366, 367;25:113,783,784 Stylotellanes A and B 21:346,356,357 Stypodiol 6:54 from Stypopodium zonale 6:54 Stypodiol methyl ether 6:55 14-deoxy-stypodiol from 6:55 reaction with Jones reagent 6:55 Stypoldione 5:439;6:55;17:8 from Stypopodium zonale 6:54 Stypopodium 25:691 Stypopodium flabelliforme 25:690; 28:432
759
Stypopodium zonale 5:439;6:54;21:275 stypodiol from 6:54 stypoldione from 6:54 Styracaster 25:872 Styracaster caroli 15:75,76 carolisterol A-C from 15:75,76 Styrene-quinone reactions 16:551-552 Styrenes 16:551;27:753 cycloaddition reactions of 16:561 epoxidation of 27:753 polymerization of 16:551 Styryl azide thermolysis 3:314,315 Styrylpyrones 9:393-395,403 Suaveoline 13:383,390,391,402,403 synthesis of 13:408,411-418 Suavioside A 27:14,22 strucutre of 27:24 Suavioside B 27:14,22,23 structure of 27:23 Suavioside G 27:14,22,24 structure of 27:24 Suavioside H 27:14,22,24 structure of 27:24 Suavioside I 27:14,22,24 structure of 27:24 Suavioside J 27:14,22,24 structure of 27:24 Subacute toxicity 27:307 from animals 27:307 of stevioside 27:308 Subclone 5:448 of BALB/c 3T3 embryo derived mouse fibroblasts 5:448 Subcosine I 1:367,370 (+)-Subcosine I 16:477 synthesis of 16:477 Subcosine II 1:367,368 Subcutaneous pentylenetetrazole Seizure threshold test (ScPTZ) 22:508 Subellinone 22:660 Suberea creba 25:719 Suberenol 20:497 from Pleisopermium alatum 20:497 Subergorgia suberosa 13:26 Subergorgic acid 3:6,60;13:26-29 Suberin 25:655,658,666;26:1262
Suberosenone 25:695 Suberosin 20:497 from Pleisopermium alatum 20:497 Suberosol 22:97 Subproside II 25:95 Subproside IV 25:96 Subproside 111 25:97 Subproside V 25:95,104 Subproside VI 25:95 Subproside Vll 25:95 Substantial kinetic isotope effect 11:212 2-Substituted 2,4,5-trimethyl- 1,3dioxolanes 14:480 "with mixed hydride reagent" (LiAIH4/A1C13) 14:480 3-Substituted 2'-hydroxyflavonoids 5:631 tri-Substituted azulenes 14:339-351 Substituted benzo[c] phenanthridines 4:544 in cancer chemotherapy 4:544 3-O-Substituted glycals 10:343 from (1,3-dimethyl-2,4-dioxo1,2,3,4-tetrahydro-pyrimidin-5yl) mercuric acetate 10:343 2-Substituted glycals 10:348 ct-anomers from 10:348 5-Substituted indolizidines 11:245 N-Substituted oxazolidin-2,4-diones 12:464 2-Substituted oxepanes 10:215,216 Substituted phenols 16:571-638 biogenesis-like transformation of 16:571-638 2-Substituted quinolines 3:391-393,395 4-Substituted quinolines 3:396 5,6-Substituted tetralin 8:396 c~-adrenergic activity of 8:396 6,7-Substituted tetralin 8:396 [3-adrenergic activity of 8:396 N-Substituted valiolamine derivatives 7:47 (R)-4-Substituted-2-oxazolidinones 12:435,436 from (R)-N-Boc-2-aminoalcohol 12:435,436
760
use as chiral auxiliaries 12:435,436 4-Substituted-2-oxazolidinones 12:416,417 from ketopinic acid 12:416,417 from 4-methoxy-2-oxazolidinones 12:435-438 optical resolution of 12:437,438 preparation of 12:437,438 Substrate binding domain 17:487,494 for HLADH 17:500,502-503 surrogates 17:498 Substrate control 23:16 Substrate specificity 27:745 of peroxidases 27:745 Subtilase (SBT) 25:388,390, 391,392,402 Subtilisin 25:388 Subtilisin/kexin-isozymel (SKI 1) 25:390 Subtilisin-like serine protease 25:388 Subulitermes bailey 14:451,452 eudesm-11-en-4-ols from 14:451 neointermedeol from 14:451,452 Subulitermes oculatissimus 14:451 neointermedeol from 14:451 Subulitermes parvellus 14:451 neointermedeol from 14:451 Succinate 22:255 Succinate dehydrogenase 26:800 Succinate ubiquinone oxydoreductase inhibitions 26:924 Succinic acid 21:398 Succinic acid dehydrogenase 7:387 Succinimidochloroformate 21:165 Succinoxidase 22:328 Succinoyl-andrographolide 29:588 effects on furin 29:588 Succinyl betulinic acid 25:61 Succinyl CoA 11:195-197 (2R)-methylmalonyl CoA from 11:195-197 Suchilactone 18:590 Sucrase 7:38,57,69,181;10:504,505 castanospermine inhibition with 7:12 Sucrase isomaltase 10:498 Sucrononic acid 15:6
Sucrose ([3-D-fmctofuranosyl)- 1-thio-c~D-glucopyranoside 2:414;8:325; 27:3,4,5 as sweetener 27:3 1-thio analog of 8:322 FD spectrum of 2:52 synthesis of 8:322 Sucrose substitutes 27:4,5 acesulfame-kas 27:4 sweetness of 27:4,5 aspartame as 27:4 cyclamate as 27:4 glycyrrhizin as 27:5 mogroside V as 27:5 neotame as 27:5 saccharin as 27:4 sucralose as 27:4 sucronic acid as 27:4 super aspartame as 27:5 Sucupira branca 29:103 Sudha and Nagarajan 29:472 carbaaldopyranoses synthesis by 29:472 SUDHL-4-1ymphoma 21:138 Sufentanil 30:200 as morphine analogue 30:200 Suffruticosol A-C 26:555,566 Sugar aglycone linkage 7:154,157,158 cleavage ",y diazomethane 7:155,1J6 Sugar analogs 6:351-384 Sugarcane cystatins 29:593 effects on cysteine proteases 29:593 Sugar components 11:213-219 Sugar derivatives 20:116 Sugar derived heptosyl bromide 30:440 as substrate 30:440 Sugar derived heptosyl bromide 30:440 in KDN synthesis 30:440 in Neu5Ac synthesis 30:440 Sugar enones 10:337 Sugar impersonator 7:14 swainsonine as 7:14 Sugar protons 30:240 stereochemistry of 30:240 Sugar sweetner mechanism 27:4,12 non-sugar sweetner system 27:11,12
761
Sugar-epoxide 14:168 reductive cleavage of 14:168 Sugar-peptide structures 6:385-420 reactions of 6:385-420 relation to peptidoglycan 6:385420 synthesis of 6:379-414 Sugars 4:349-359 as chiral building blocks 4:349359 L-Sugars 4:504 advantages of 4:504 Sugar-shape alkaloids 12:276 Sugiol 20:670;23:682 from Salvia napifolia 20:670 Suicide inhibitors 9:593;27:347;27:348 for abscisic acid 8'-hydroxylase 27:347 of 8'-hydroxylase 27:348 Suicide substrates (irreversible inhibitors) 7:36-40 Suillus 29:271 Sulcatol 1:692 conversion to pityol 1:692 synthesis of 1:691,692 5'-O-Sulfanoyl-2-chlorodensine 25:781 Sulfate olefaction 27:678 of sandrosaponin I-X 27:678 of saponin 27:678 Sulfated pentapeptide 25:376,377 Sulfated sterols 7:285 from Strongylocentrotus intermedius 7:285 Sulfated trisaccharide moiety 27:673 34-Sulfatobastadin 13 28:695 as endothelin A receptor inhibitor 28:695 c~-Sulfenylacetamide 3:461 cyclization to erythrinans 3:461 trans-Sulfenylation 12:73,76 intramolecular 12:73,76 Sulfer-containing furanosesqui-terpenes 25:814 Sulfhydryl compounds (SH) 22:442 Sulfide contraction reaction 6:438,439 Sulfide isoquinolines 25:824 Sulfide pyridoacridines 25:819 Sulfide pyrroloquinolines 25:822
Sulfide-containing pyrroloiminoquinones 28:685 as antileukaemic agents 28:685 prianosin A as 28:685 structure of 28:685 Sulfidopeptide lipoxins 9:576 Sulfinates 4:490 Sulfinemycin 26:443 Sulfinyl carbanion 1:451 Sulfinylesters 4:491-494otin aldol type condensations 4:491-494 synthesis of 4:490,491 Sulfircin 28:672 as N, N-dimethylguanidinium salt 28:672 hipposulfates A from 28:672 Sulfite reductase 9:603 Sulfobus solfataricus 25:720 Sulfoethyl glucan (SEG) 23:139 Sulfonation 16:127 of endo-3-bromocamphor 16:127 Sulfone 28:715 as constituent of Mediterranean sponge 28:715 Sulfone anion addition 1:471 to epoxide 1:471 Sulfone coupling reaction 4:526,528 Sulfones 17:91 Sulfonic acid 25:900 Sulfonium ion-induced cyclocarbamation 12:487 Sulfonoceramides 25:868 Sulfonoglycolipids 25:868 Sulfonolipids 25:868 Sulfonyl group 6:342 1,3-rearrangement of 6:342 O-Sulfonylation 12:338 Sulfonylurease 21:459,488 Sulfoquinovosyl diacylglycerols (SQDG) 25:868 Sulforhodamine B (SRB) method 25:267 Sulforhodamine B 20:524,537 Sulfoxidation 27:752 of methyl p-tolyl 27:752 Sulfoxides 4:489-491;6:310;14:517-519 preparation of 14:517-519 monochlorinated sulfoxide from
762 6:310 synthesis of 4:489-491 6-Sulfo-a-D-quinovopyranosyl-(1-7 3)l',2-diacylclycerol 25:868 Sulfur 6:307-349 properties of 6:307,309 Sulfur accumulation 2:275 in liverworts 2:275 Sulfur analogue 12:160,161 by Pummerer rearrangement 12:160,161 from (R)-2-methyl- 1,3-butanediol 12:160,161 Sulfur stablized carbanions 3:81,82 Sulfur-assisted C-C bond formation 6:308 Sulfur-containing compounds 17:81 Sulfur-containing cyclic peptides 28:678 biological activities of 28:678 cytotoxicity of 28:678 discodermin A as 28:678 discodermin B as 28:678 discodermin C as 28:678 discodermin D as 28:678 Sulfur-containing diketopiperazine cyclo-(L-Pro-thiopro) 25:828 Sulfuretin 22:427 Sulfuric ammonia precipitation 30:825 enzyme isolation by 30:825 Sulphated glycoprotein 23:163 Sulphated polysaccharide (PS) 30:398, 400,405 anti-CMV activity of 30:405 anti-HIV activity of 30:398 antiviral activity against HIV 30:400 effect on viral replication 30:400 from marine sources 30:400 inhibitory effect of 30:398 mechanisms of action of 30:400 Sulphated polysaccharide (PS) extracts 30:399 from brown algae 30:399 from red seaweed 30:399 inhibitory activity of 30:399 Sulpheno-cycloamination 1:228 Sulphonation 4:628,633,634 of camphor 4:628
of (+)-endo-3-bromocamphor 4:628 regiospecific 4:633,634 Sulphonium ylids 13:144 sigmatropic rearrangement of 13:144 Sulphonylurea drugs 25:534 Sulphur trioxide/pyridine complex 30:527 chlorosulphinic acid from 30:527 pyridine from 30:527 Sulphuretin 22:424 Sulphurisation 9:371,372 of 4-t-nonylphenol 9:372 Sultam 1:24,25 SUMT 9:603,604,606 Supercritical fluid chromatography (SFC) 9:464,466 Sunflower cystatin phytocystatin 29:593 effects on cathepsin H ficin 29:593 effects on papain 29:593 Sunflower multicystatin 29:593 effects on papain 29:593 Sunillin 22:77 Sunwa 23:655 Supella longipalpa 22:377 Supercritical fluid (SF) 23:467 Supercritical fluid extraction (SFE) 21:576;23:467 Super-hydride 3:279;22:435 reduction with 3:279 Superoxide dismutase 22:309; 25:931;26:974 Superoxide dismutase activity 21:669 Superstolide A 19:597 absolute configuration of 19:597 NOESY data of 19:597 relative stereochemistry of 19:597 Superstolide A&B 26:1209 Supinidine 1:229,233,234,237,248250,259,339;3:51,54 Supinine 1:339;26:874 Suppressing activity 30:308 on cells proliferation 30:308
763
Suppurative dermatitis 22:607 use of Platycodon grandiflorum in 30:88 1,3-Suprafacial migration 8:297 Suramin 26:342,791 Surangin B 4:390,391 from Mammea longifolia 4:391 Surface ionization techniques 2:46-53 Surface-immunoglobulins 18:915,916 Susceptible Burkitts lymphoma (BL) 25:272 apoptosis in 25:272 (-)-Suspenol 16:595-601 enantiospecific synthesis of 16:595-601 stereo structure of 16:592,595 Suspensaside 5:513 antihypertensive activity of 5:513 Suspension cultures 7:92,93 Suspensolide 8:234-236 synthesis of 8:234-236 oxy-Cope rearrangement of 8:234 from Anastrepha suspensa 8:222 E,E-Suspensolide 8:236 via Mitsunobu cyclization 8:236 Z,E-Suspensolide 8:236 Sustantia nigra 22:24 Sutcatol 25:143,144,145,163 Suvanine 28:670 as acetyl cholinesterase inhibitor 28:670 total synthesis of 28:672 Suzuki coupling 21:148;26:1248 oforganoboronic acids 16:435 Suzuki coupling reaction 30:19,22 Suzuki methodology 21:382 Suzuki reaction 20:300 Suzuki-Miyaura 29:396 steganes synthesis by 29:396 Suzuki-Miyaura cross coupling 26:74 of 4-bromo- 1-butyl-9borabicyclononane 26:74,75 Suzuki-type coupling 20:445 Swainosonine 22:30 Swainsona canescens 12:313;27:515 (-)-swainsonine from 12:313 Swainsona galegifolia 27:255
Swainsona sp. 7:11;10:558;27:514 8a-epi-Swainsonine 1:280 synthesis of 1:280 (-)-Swainsonine 12:313 absolute configuration of 12:313 biosynthesis of 12:313,314 enantiospecific synthesis of 12:313,314 from (-)-(1S,2R,8aS)indolizidine- 1,2-diol 12:303 from Astragalus emoryanus 12:313 from Astragalus lentiginosus 12:313 from Astragalus oxyphysus 12:278 from Metarhizium anisopliae 12:313 from Oxytropis sericea 12:313 from Rhizoctonia leguminicola 12:313 from Swainsona canescens 12:313 relative configuration of 12:313 stereoselective synthesis of 12:330 synthesis of 12:313-325 (-)-l-epi-Swainsonine 12:322,325 from (S)-glutamic acid 12:325 (-)-8-epi-Swainsonine 12:325 benzylidene-3-deoxy-cz-Dglucopyranoside 12:326, 327 divergent synthesis of 12:330 from (R)-glutamic acid 12:325 synthesis of 12:328 (-)-Sa-epi-Swainsonine 12:330 divergent synthesis of 12:330 from 2,3-O-isopropylidene-Eerythrose 12:330, 331 synthesis of 12:328,329 Swainsonine 7:32,44,112; 22:183;27:515 absolute configuration of 7:14;10:558 as sugar impersonator 7:14 asymmetric epoxidation of 10:561
764
biological activity of 27:252 enantioselective synthesis of 10:561 enantiospecific synthesis of 10:564 from Astragalus lentiginosis 7:11 from Astragalus lentiginosus 10:558 from Metarhizium anisopliae 10:558 from Rhizoctonia leguminicola 10:558 fromSwainsona species 10:558 from gastrointestinal tract 27:525 Horner-Emmons olefination of 10:561 immunomodulation by 7:16 isolation of 19:487 inhibition ofnaranginase 27:255 inhibition of (+)-ramannosidase by 27:255 inhibition cellular mannosidases by 27:252 lysosomal inhibitor of 10:559 mannosidase I inhibitors 10:527 mannosidase II inhibitors 10:527 relative configuration of 10:558 synthesis of 1:280,281,289, 290;10:541 ;19:487 ot-mannosidase inhibition by 7:11 epi-Swainsonine 7:44 (-)-Swainsonine N-oxide 12:276 Swainsonine stereomers 12:325 Swallowed garlic 23:465 Swartzia madagascariensis 7:417,427, 429,431,432 Swartzia pickellii 29:606 Swartzia simplex 7:427,429 Sweet orange 23:747 Sweet taste 27:10,11 activation by receptorindependent mechanism 27:12 receptor for 27:11 Sweeteners 2:357 Sweetness inducers 27:39,40 arabinogalactin as 27:39
caffeic acid conjugates cynarin as 27:39 chlorogenic acid as 27:39 curculin as 27:39 miraculin as 27:39 strogin 1 as 27:39,40 strogin 2 as 27:39,40 strogin 4 as 27:39,40 Sweetness inhibitors 27:40-43 alternoside I as 27:41 altemoside II as 27:41 alternoside III as 27:41 alternoside IV as 27:41 alternoside V as 27:41 from Gymnema alternifolium as 27:40 from Gymnema sylvestre as 27:40-43 from Hovenia dulcis Thumb. as 27:40 from Stephanotis lutchuensis var. japonica as 27:40 from Ziziphos jujuta P. Miller as 27:40 gymaemasaponin III as 27:41,43 gymaemasaponin IV as 27:41,43 gymaemasaponin V as 27:41,43 gymnemlc acid I as 27:41,42 gymnemlc acid II as 27:41,42 gynmemlc acid III as 27:41,42 gymnemac acid IV as 27:41,42 gynmemac acid IX as 27:41,42 gynmemlc acid V as 27:41,42 gynmemac acid VI as 27:41,42 gynmemac acid VIII as 27:41,42 gynmermc acid X as 27:41,42 gynmermc acid XI as 27:41,42 gymnemic acid XII as 27:41,42 gymnemic acid XIII as 27:42,42 gymnemic acid XIV as 27:41,42 gynmemic acid XV as 27:41,42, 45 gymnemic acid XVI as 27:41,42, 45 gymnemic acid XVII as 27:41, 42,45 gynmemic acid XVIII as 27:41, 42,45 hoduloside I as 27:41
765 hoduloside II as 27:41 hoduloside III as 27:41 hoduloside IV as 27:41 hoduloside IX as 27:41 hoduloside V as 27:41 hoduloside VII as 27:41 hoduloside VIII as 27:41 hoduloside X as 27:41 hovenoside I as 27:41 jujubasaponln II as 27:41 jujubasaponln III as 27:41 jujubasaponm IV as 27:41 jujubasaponln V as 27:41 jujubasaponln VI as 27:41 jujubasaponm zizyphus saponin III as 27:41 jujuboside B as 27:41 saponin C2 as 27:41 saponin E as 27:41 saponin H as 27:41 sitakisoside XIII as 27:41 sitakisoside XVI as 27:41 sltakisoside XVIII as 27:41 sltakisoside I as 27:41 sitakisoside II as 27:41 sitakisoside III as 27:41 sitakisoside IV as 27:41 sltakisoside IX as 27:41 sitakisoside V as 27:41 satakisoside VI as 27:41 sltakisoside VII as 27:41 sitakisoside VIII as 27:41 sltakisoside X as 27:41 sitakisoside XI as 27:41 sitakisoside XII as 27:41 zlziphin as 27:41 Zizyphus saponin I as 27:41 Zizyphus saponin II as 27:41 Swenton's bicyclic intermediate 14:13 Swem method 19:452 Swern oxidation 1:451;4:19,200,210, 418,425 ;5:20,21,254-257,386,447, 449,497,705-708,821-824,826;6:11, 13,21,25,50,57,58,62,66,67,74,75,11, 9,120,129,192,193 ;8:3-59,64,65,68, 69,81,82,115-135,139,157, 159-172,175-201,205-217,219-256, 261,274,277-282,283-292,315-350, 359- 370,373-392,395-406,409-428,
433-463,466,467,478 ;9:37,224,225, 228,241-243,248,343-369,434; 10:3-42,47,51,52,59,65,69,70, 77-145,155,156,159,166,167,168, 171,180,188,241-302,307-311, 315-317,320-323,330,331,350,351, 386,414,418,419,421,423-428,436, 437,439-448,457-493,507-511, 514-516,532,534,551,552,561, 585-627,629-669,682-685;11:3-69, 71-111,117,119-144,151-172, 229-275,277- 377,379-425,429-480; 12:9-33,35-62,65-95,113-135, 145-177,181-225,233-274,275-363, 375-383,411-444,445-498;13:2,3,22, 84,108-120,125,132,138,139,142, 165,187-255,264-281,288,289,328, 353-367,383-471,473-518;18:91, 176-178,198,201,210,260,282,283, 297,475,623,633,641 ;19:22,33,42, 45,62,207,238,296,304,307,341,373, 426,452,473,497-498;20:50,75,592 in synthesis of (-)-warburganal 4:418,425 of (+)- 1O-O-methyl- 18,19dihydrohunterburnine 14:706-708 of (+)-11-epiambinine 14:790,791 of (+)- 11-epicorynoline 14:785- 787 of (+)- 11-epiisocorynoline 14:785-787 of (+)- 16-hydroxydihydrocleavamine 14:850-853 of (+)- 18,19-dihydroantirhine 14:406-408 of (+)- 18,19-dihydrohunterbumine 14:406-408 of (+)-3-epi-18,19dihydroantirnine 14:707,708 of (+)-3-epicorynantheidol 14:790,791 of (+)-5-epi-nardol 14:374,375 of (+)-alloaromadendrane4b, lOa-diol 14:379-384 of (+)-alloaromadendrane4c~, 10a-diol 14:379-384
766
of (+)-alloyohimbane 14:710,711 of (+)-ambinine 14:788-791 of (+)-bulnesol 14:365 of (+)-chelamine 14:793-795 of (+)-chelidonine 14:793-795 of (+)-confertin 14:362 of (+)-corynanthediol 14:709,710 of (+)-corynoline 14:785-787 of (+)-eburnamonine 14:728 of (+)-epialloyohimbane 14:710,711 of (+)-homochelidonine 14:796 of (+)-isocorynoline 14:785-787 of (+)-tirandamycin A 14:120123,129-132,134-138 of (+)-tirandamycin B 14:123126 of (+)-vincamine 14:726 of (+)-a-bulnesene 14:364,365 of (-)-(10R)-hydroxydihydroquinine 14:564,565 of (-)-7-deoxydaunomycinone 14:493,494 of (-)-ajmalicine 14:563,564 of (-)-allo-yohimbane 14:267,277,278 of (-)-ambrox 14:420-425 of(-)-chokol 14:490 of (-)-eburunamenine 14:636 of (-)-eldanolide 14:272,273 of (-)-epi-ambrox 14:420-425 of (-)-eserethole 14:636-638 of (-)-esermethole 14:639 of (-)-Ireland alcohol 14:119,120 of (-)-lardolure 14:487 of (-)-N-acetylamphetamine 14:496,497 of (-)-ochropposinine 14:565 of (-)-physostigmine 14:636-638 of (-)-polygodial 14:413-421 of(-)-selin-11-en-4ot-ol 14:456465 of(-)-talaromycin B 14:538,539 of (-)-tirandamycin A 14:114117 of (-)-trans-cognac lactone
14:272-273 of (-)-trans-whisky lactone 14:272,273 of (-)-warburganal 14:413-421 of (-)-c~-selinene 14:406-413 of (-)-8-multistriatin 14:273,274 of (+)-africanol 14:487,488 of (+)-arborescin 14:365,366 of(+)-carissone 14:406-413 of (+)-dihydropinidine 14:572,573 of (+)-eburnamine 14:636 of (+)-isoambrox 14:420-425 of (+)-multistriatin 14:267 o f (+)-pedamine 14: 499 of (+)-PS-5 14:497,498 of(+)-streptolic acid 14:112-114 of (+)-tirandamycic acid 14:110112,127-129 of (+)-yohimbine 14:566,567 o f (+)-zaluzanin 14:366,367 of (+)-~-eudesmol 14:406-413 of (+)-13-eudesmol 14:490 of(E)-olefinic alcohol 19:452 of (1)-ct-santonin 14:406-413 of (R)-(-)/(S)-(+)-3'-methoxy-4'O-methyl joubertiamine 14:501,502 of (S)-2-(6-methoxy-2-naphthyl) propanoic acid 14:473 of (S)-5-hydroxy-2-penten-4olide 14:273,274 of (S)-trans-g-butenyl 14:473 of (S)-y-acetylenic-~,aminobutyric acid (GABA) 14:473 of 1,2,4,6-tetra-O-acetyl-2,3didehydro-3-deoxy-c~D-threo-hexopyranose 14:173 of 1,2,4,6-tetra-O-acetyl-3-
deoxy-ct-D-lyxo-he xop yranose 14:173 of 1,2-dehydroaspidospermidine 14:635,636 of 1,3-diols 16:11 of 10-hydroxy corynanthediol 14:709,710 of 13-methyltetrahydroproto-
767
berberine 14:790 of 16-carbomethoxyvelbanamine 14:831,832 of 16'-demethoxycarbonyl-16'epi-deoxy vinblastine 14:850-852 of 2-methyl- 1,6-dioxaspiro [4.5] decane 14:526-531 of 2'-phosphorylated ribonucleotides 14:304-312 of 2-pyrrolidones 14:560,561 of 3,4-anhydro-c~-Daltropyranoside 14:170 of 3-arylisoquinoline alkaloids 14:796-799 of 3-deoxy- 1,2: 5,6-di-O-
isopropylidene-D-xylo-
hexofuranose 14:172 of 3-deoxy- 1,2:5,6-di-Oisopropylidene-(x-D-ribohexofuranose 14:168-171 of 3-deoxy-D-ribohexofuranoside 14:164 of 3-deoxy-D-ribo-hexose derivative 14:163 of 3-deoxy-hexoses 14:143-200 of 3'-deoxykanamycin A 14:145 of 4-deoxy-D,L-xylohexopyranose 14:178 of 4-deoxy-D-lyxo-hexose 14:158 of 4-deoxy-D-ribohexopyranoside 14:164 of 4-deoxy-hexoses 14:143-200 of 5,6-methanoleukotriene 14:489,490 of 5-carba-levoglucosenone 14:279 of 5-epi-paradisiol 14:454,456465 of 7,8-demethylene sanguinarine 14:783,784 of adriamycin 14:474,475 ofaflatoxin M2 14:651-657 of alcohol 16:313,480 of alkaloids 14:632-639 of allylic alcohol 16:261 of ambergris fragrances 14:420425
of aminocyclitol 14:147 of amiteol 14:456-465 of anthracyclines 14:271 of apovincamine 14:635,636 of aspidospermidine 14:632-636 of benzyl 4,6-O-benzylidene-3deoxy-f3-D-ribo-hexopyranoside 14:153,154 of branched RNAs 14:284-303 of bulgecinine 14:193 ofcalabarbean alkaloids 14:636638 of carbohydrate derivatives 14:659-664 of cardenolide 14:440-444 of catharinine 14:847 of chelamidine 14:796 of chelerythrine 14:773-775,796 of chelirubine 14:777,778 ofchiral alkoxy-allenes 14:480 ofchiral sesquiterpenes 14:406425 of chiral steroid analogues 14:431-444 of chiral vinyl ether alcohol 14:486 of cis-c~,ot'-disubstituted pyrrolidines and piperidine 14:571-574 of cleavamine 14:810 ofcorydaline 14:790 of damascones 14:425-431 of D-and L-lividosamine 14:186193 of daunomycin 14:474,475 of daunomycinone 14:5-8,24-42 of desepoxymethylenomycin 14:602 of dihydrobenzofuranol 14:651 of dihydrochelerythrine 14:773775,796 of dihydronitraraine 14:765 of dihydrosanguinarine 14:793795 of diterpenoids 14:639-642 of d/-carbomethoxydihydro cleavamine 14:831-833 of dl-coronaridine 14:847,850853
768
of dl-dihydrocatharanthine 14:850-853 of ebumamonine 14:632-636 of emetine 14:565 of epilupinine 14:704-709 of epivincadine 14:635,636 ofeudesm-11-en-4-ols 14:449467 of fagaronine 14:775-777 of guaiani alcohol 14:374 ofhomoallylic alcohol 19:238 of hydroazulene sesquiterpenes 14:355-387 of ibophyllidine 14:847 of iboxyphylline 14:847 of indole alkaloids 14:632636,703-730 of insect juvenile hormone analogues 14:391-397 of intermedeol 14:452,453,456465 of isoeburnamine 14:635,636 of isokomarovine 14:763 of isolevoglucosenone 14:279 of isonitramine 14:543,743-747 of isoretronecanol 14:737 of isovelbanamine 14:865-869 of isovincadifformine 14:850853 of komarovicine 14:763 of komarovidine 14:763 of komarovine 14:763 of komarovinine 14:763 oflambertic acid 14:640-642 ofleurosine 14:811 of lupine alkaloids 14:731-768 of lupinine 14:737,738 of macarpine 14:781-783 of methyl 2,3,6-tri-O-benzoyl-4deoxy-D-xylo-hexopyranoside 14:158,159 of methyl 2,3-di-O-benzyl-4-
deoxy-a-D-xylohexopyranoside 14:153 of methyl 3-deoxy-4,6-O-
benzylidene-D-lyxohexopyranoside 14:167 of methyl-2,3,6-tri-O-benzoyl-4O-(trifluoromethane sulfonyl)-
[3-D-galactopyranoside 4:164 of minovine 14:635,636 of modhephane 14:490 of monomorine I 14:575 of N-acetyl-D-lividosamine 14:188,191 of naphtho [2.3.c] pyran-5,10quinone antibiotics 14:271 of naproxene 14:505 of neointermedeol 14:453,454, 456-465 of nitidine 14:775-777 of nitramine 14:743-747 of nitrarine 14:765 ofnitraramine 14:751-754 of Nitraria alkaloids 14:731-768 of N-methyl decarine 14:783,784 of oligoribonucleotides 14:283312 of oxaunomycin 14:493-495 of oxychelerythrine 14:773-775 of oxyterihanine 14:775-777 ofpandoline 14:831-833 of paradisiol 14:453,456-465 of penta-O-acetyl-Dglucopyranose 14:659-664 of penta- O-acetyl-D-isopyranose 14:659-664 of piperidine 14:553-559 ofpiperidine derivative 14:572 ofpodocarpic acid 14:639-642 of polysaccharides 14:201-259 of Prelog-Djerassi lactoic acid 14:267 of primary alcohol function 19:42 ofpropargylic alcohols 14:473 of punctatin 14:646,647 ofpurpurosamine C 14:268 ofpyrethrin analogues 14:391397 of pyrrolidine 14:553-559,568571 of quebrachamine 14:632-636 of quinolizidine alkaloids 14:731-768 of reserpine 14:267 of rose oil components 14:425431
769
of sanguilutine 14:777,778, 780,781 of sanguinarine 14:793-795 of seco-dehydroabietane 14:642 of securinine alkaloids 14:657659 of serricornin 14:267,275 of sibirine 14:744 of sibirinine 14:742,743 of spiro [4.5] decane 14:544-546 of stereoisomers of eudesm- 11en-4-ols 14:456-465 of streptolydigin phosphonate tetramic acid 14:117,118, 132-134 of taxodione 14:667-702 of tetrahydroalstonine 14:563, 564 of tetrahydrocorysamine 14:790 oftetramic acid 14:110 of tetrodotoxin 14:267,276,277 of thalictricavine 14:790 of velbanamine 14:810,865-869 of vinblastine 14:805-884 of vincadifformine 14:635,636 of vincadine 14:635,636 of vincamine 14:635,636 of vincaminorine 14:635,636 of vitamin E and K 14:478,479 of c~-cyanobenzyl alkyl ether 14:473 of a-linked 3'-deoxy cyclitol 14:147 of 13-adrenergic blocking agents 14:473 of 13-cyperone 14:406-413 of [3-damascenone 14:430-432 of 13-elemol 14:406-413 of T-citromycinone 14:8-10 of tc-tabersonine 14:847 of primary alcohol 30:45 Swern reaction 4:425;6:125;9:526; 11:90 Swern-Wittig protocol 19:22 Sweroside 25:471,476;26:103,104 chemical transformation of 26:103,104
serum ALT activity of 25:471, 476 Swertiajaponica 22:533;25:476 Swertiaperennis L. 22:533 Swertia purpurescens 22:533 Swertia randaiensis 22:533 Swertia sp. 25:471 Swertianoline 22:521,533,541 Swietenia mahagoni 25:943 Swinfolide 5:356,357;396,397; 15:589;25:730,731 Swinholide A 18:186-190;26:1229 paterson's synthesis of 26:1229 synthesis of 18:186-190 stereostructure of 19:589 X-ray analysis of 19:589 Swinholide A&B 26:1196,1227 Swinhonsterols A-C 26:1178 Swinolides D-G 26:1198 Sydnone 1:343 Sylibum marianum 22:428,431,440 Sylvaticin 9:399;26:793 Sylvestroside I 7:443 Symbiodinium sp. 25:722 Symbiotic algae 23:234 Symbiotic marine microorganisms 23:185 bioactive metabolites 23:185 Symbiotic zooxanthellae 23:177 Sympathetic ganglia 30:782 blockade of 30:782 Sympathetic nerve activity 30:787 Sympathomimetic amines 12:411 Symphacia obvelata 26:463,471, 478,493 Symphomyrtus subgenus 24:233 euglobals of 24:233 Symphonia globulifera 22:659 Symphytoside A 9:61,62 Symphytum 29:582 Symphytum officinale 9:60-62; 21:670;28:400 saponins from 9:60-62 Symploca hydnoides 25:887
Symplocos helminthosporium carbonum 27:498
Symplocos lancifolia 27:17,33,34 phlorizin from 27:17,33,34
770
Symplocos microcalyx 27:17,34 trilobatin from 27:17 Symplostatin 25:2;25:886,887 Syn elimination 16:335,357 of selenoxide 16:335 of trifluroacetate 16:357 Syn hydrostannation 19:62 Synapic potential mediation 28:318 by non-NMDA receptors 28:318 Synaptic actions 30:381 of serotonin 30:381 Synaptic dopamine transporters 25:539 Synaptic glycine transporters 25:539 Synaptic serotonin transporters 25:539 Synaptogenesis 30:368,377 effect of serotonergic neurotransmission on 30:368 role in rodents 30:377 role of serotonin in 30:377 Synaptolepis kirkii 22:533 for epilepsy 22:533 Syndrome type- 1A 26:1130 adipose tissue distribution as 26:1130 cerebellar dysfunction as 26:1130 liver insufficiency as 26:1130 peripheral neuropathy as 26:1130 psychomotor retardation as 26:1130 Synechococcus leopoliensis 26:359, 362-364 Synechococcus sp. 21:304,305 Synechocystis PCC 26:366 Synechocystis trididemni 10:251 Syn-enoate 8:140 Syn-epoxidation 16:442 Synergies interaction 21:601 Synergistic activity 21:673 Synergistic effect 21:608,611; 30:498,596 ofhervelines B 30:596 ofhervelines C 30:596 of retinoids 30:498 of vitamin D derivatives 30:498 Synergistic interaction 21:698 of acyclovir(ACV) 21:698
of ganciclovir (GCV) 21:698 with ganciclovir (GCV) 21:698 Synergistic purgative actions 30:306 of rheinanthrone 30:306 of aloe-emodin-anthrone 30:306 Syn-isomerization 11:220,221 metal ion-assisted 11:220,221 tertiary allylic isomer from 11:220,221 Synoicum prunum 25:723 Synthase 9:435 Synthesis 21:161,391,706-717,741-743, 746-748,757 ;23:813 ;24:1-47,53-125, 175-213,488,491,573-672,686, 744-755,779,780; 26:635-637,642; 27:197,204,207,778;28:234,331, 332,338,495,503,508,640,670;29: 169,298,299,355,356,421,433 ;30: 370,485-494,504,608 from c~-amyrin 29:583 from fukinolic acid 29:582 from methyl 3-(indol-3yl)pyruvate 29:231 glucopyranose 8:316,318 in vitro 30:608 of 9-oxo-6,72H,1 lfll-I-eudesm-4en-6,12-olide 24:79,80 of(+) HON 13:512-513 of (+)-l-epi-slaframine 12:309 of (+)-l-oxoindolizidine 12:279, 28O of (+)-2-oxoindolizine 12:283, 284 of (+)-5-epipumiliotoxin 18:340 of (+)-6-demethylstatine 13:514 of (+)-6-epi-slaframine 12:311,312 of (+)-apovincamine 18:331 of (+)-cathenamine 13:490,491 of (+)-cis-1-hydroxyindolizidine 12:279 of (+)-dihydroanatoxin-A 13:494 of(+)-elacokanine C 12:289-293 of(+)-elaeokanine A 12:289; 13:487 of(+)-elaeokanine C 13:487 of (+)-epilupinine 13:483,484
771
of (+)-eremophilone 15:243 of(+)-gabaculine 13:509,510 of (+)-indolyzomycin 12:301-330 of (+)-isoretronecanol 13:483, 484 of (+)-mesembrine 13:492,493 of (+)-Na-benzyl-20-desethylaspidospermidine 18:323 of (+)-nanaomycin-A 11:127-130 of (+)-nupharolutine 13:488,489 of (+)-O-methylpallidinine 12:470,471 of (+)-pleuromutilin 8:418 of (+)-semivioxanthin 11:130, 131 of (+)-seychellene 8:412, 423-425 of (+)-slaframine 12:307-312 of (+)-statine 12:432,433 of (+)-tashiromine 18:353 of (+)-tetrahydroalstonine 13:490,491 of (+)-tetrangomycin 11:135-139 of (+)-~-allokainic acid 13:508, 516 of (+)-8-coniceine 13:486,487 of (-)-(1R,8aS)- 1-hydroxyindolizidine 12:281 of (-)-(1S,2R,8aR)-indolizidine1,2-diol 12:303,304 of (-)-(1S,2R,8aS)-indolizidine1,2-diol 12:303,305 of (-)-l ,8a-epi-slaframine 12:312 of (-)- 1-epi-castanospermine 12:333-335,344 of (-)-8,8a-di-epi-swainsonine 12:329-332 of (-)-8a-epi-swainsonine 12:328,329 of (-)-8-epi-castanospermine 12:344 of (-)-8-epi-swainsonine 12:328 of (-)-alstonerine 13:383 of (-)-anatoxin-A 13:493,494 of (-)-aristeromycin 8:148,149
of (-)-eudesma-3,5-diene 24:116,117 of (-)-E-[3-santalene 8:145,146 of (-)-E-[3-santalol 8:145,146 of (-)-hobartine 11:280-283 of (-)-indolizidine alkaloids 11:246-267 of (-)-isostegane 24:779,780 of(-)-muscone 10:330,331 of (-)-patchoulol 8:423-425 of (-)-peduncularine 11:284,285; 13:491,492 of (-)-periplanone B 8:227 of (-)-phoracantholide I 10:320- 323 of (-)-rhazinilams 29:364 of (-)-specionin 10:425,426 of (-)-steganacin 24:779 of (-)-stegane 24:779,780 of (-)-Z-[3-santalol 8:145,146 of (-)-[3-santalene 8:145,146 of (-)-[3-mrmerone 8:51-54 of (+)-(15S)-prostaglandin A2 10:418 of (+)-(1S,8aS)-1-hydroxyindolizidine 12:281 of (+)-(6R,7S,8S,8aR)-trihydroxyindolizidine 12:347 of (+)-(6S,7R,8R,8aR)-trihydroxyindolizidine 12:347,348 of (+)- 1,8a-di-epi-castanospermine 12:335,336 of (+)-6,7-di-epi-castanospermine 12:342-344 of (+)-6-deoxycastanospermine 12:337,338 o f (+)-6-ep i- cas tano spermine 12:342-344 of (+)-acetomycin 10:443-448 of (+)-allopumiliotoxins 267A 12:297 of (+)-allopumiliotoxins 339B 12:298-300 of (+)-aristofruticosine 11:323-325 of (+)-aristoserratine 11:296 of (+)-aristoteline 11:280-283 of (+)-asteltoxin 10:439-442
772
of (+)-biotin 13:514-516 of (+)-castanospermine 11:267-271 of (+)-castanospermine 12:321, 332-342,353,354 of(+)-colart N 24:58,59 of (+)-compactin 11:335-377; 13:555-615 of (+)-hastanencine 12:472 of (+)-heliotridine 12:472-474 of (+)-mdolizidine alkaloids 11:246-267 of (+)-isoeremolactone 8:423, 425-428 of (+)-makomakine 11:280-283 of (+)-mevinolin 11:335-377; 13:561 of (+)-monomorine I 11:231-244 of (+)-picrasin B 11:76,77 of (+)-pseudoephedrme 12:479, 480 of (+)-quassin 11:76,77 of (+)-steganacm 24:779 of (+)-streptazoline 13:514,515 of (+)-thienamycin 13:498-504 of (+)-tuberiferm 24:56,57 of(+)-A 2"3picrasin B 11:76,77 of (+)-c~-homonoj irimycin 11:431,432 of (+)-c~-santalol 8:145,146 of (+)-fl-cyperone 24:116,117 of (+)-3[3-hidroxinagilactone F 28:503 of (1 ~ 1)-aldosyl aldoside 8:317-327 of (1--,2) aldosyl ketoside thiodisaccharide 8:324 of (1---~2) linked thiodisaccharides 8:327,328 of (1---~4) linked thiodisaccharides 8:331-338 of (2R,3R)-3-hydroxyglutamic acid 12:477 of (2S,3 R)- 3-amino-2-hydroxy-4phenylbutyric acid (AHPBA) 12:433,434 of (2S,3 R)-[5-hydroxy-L-glutarnic acid 12:431,432
of (3R)-7-amino- ~-hydroxybutyric acid 12:434 of (3R,4S)-4-methyl-3-heptanol 11:415,416 of (3S,3R)-3-amino-2-hydroxy-5methylhexanoic acid (AHMHA) 12:433,434 of(3S,4R)-statine 12:480;13:513 of (3S,4S)-4-methyl-3-heptanol 11:412,413,415 of a-amyrin linoleate (c~-amyrin cis-9, cis- 12-octadecadienoic acid ester) 29:583 of c~-amyrin linoleate (c~-amyrin cis-9,cis- 12-octadecadienoic acid acid ester) 29:585,586 of ot-amyrin palmitate (c~-amyrin hexadecanoic acid ester) 29:583 of (d, /)-bulnesol 10:310,311 of (d,/)-trichodiene 10:307-309 of (d/)-acorenone 10:315-317 of (d/)-ot-cuparenone 8:3,4 of (E)-3-bromoacrylates 8:150, 151 of (E)-trans- 1-hydroxy- 10-vinyl2-cyclodecene 8:196 of (E,E)-diallylic ether 8:176 of (E, Z)-2,6-cyclodecadiene 8:177 of (R)-(-)-homolaudano sin 13:494 of (R)-(+)-tetrahydro-palmatine 10:682,683 of (R)/(S)-homoproline 13:513, 514 of (S)-pinanediol 11:410 of (Z)-trans- 1-hydroxy- 10-vinyl2-cyclodecene 8:196 of (ot-chloroalkyl) boronic ester 11:410 of (c~-haloalkyl) boronic ester 11:425 of 1,2-disaccharide 8:362,366 of 1,3,5-trihydroxyacridin-9-one 13:357,358 of 1,3-dihydroxyacridin-9-one 13:355
773
of 1,5-dihydroxy-2,3-dimethoxy10-methylacridin-9-one 13:354, 355 of 11-ene-eudesmanes 24:110, 111 of 11-hydroxyeudesmanes 24:110-112 of 11-hydroxynoracronycine 13:356-358 of 1 lfl-angeloxy-a-santonin 24:69,70 of 14c~-hydroxymarcfortine A 28:338 of 15-tritiated GA3 8:128,129 of 16c~-hydroxymarcfortine A 28:338 of 19,10-thio-3-epi-gibberellin A~ 8:125,126 of 19,10-thiogibberellins 8:125 of 19,20-dehydrotalcarpine 13:411,427,428 of 1-aldo-C-glycosides 10:350, 351 of 1-aryl bicyclo [3,10] hexane derivatives 8:12 of 1-aryl-2-methyl cyclohexane 8:9 of 1-aryl-2-methyl cyclopentane 8:9 of 1-deoxy-8-epi-wangustin 24:104-106
of 1-deoxyivangustin 24:104-106
of 1-deoxynojirimycin 12:332 of 1-methyl- 1-phenyl-2(methylseleno)methyl cyclopentane 8:7,8 of 1-O-acetyl oxetanose 10:597-604 of 1-thio analog of sucrose ([3-Dfructofuranosyl 1-thio-c~-Dglucopyranoside) 8:324 of 1-thiosucrose 8:326 of 1-thio-c~,c~-trehalose 8:318 of 1ct,24R-dihydroxyvitamin D3 11:384,385 of 1c~,24S-dihydroxyvitamin D3 11:384,385
of 1a,25-dihydroxy-(24R)fluorocholecalciferol 10:69 of 1~,25-dihydroxycholecalcifero126,23(S)-lactone 10:59 of 1c~,25-dihydroxyvitamin D2 11:393-395 of 1~,25-dihydroxyvitamin D3 11:384,385 of 1~,25S,26-trihydroxycholecalciferol 10:69 of 1c~,313-diacetoxy-23,24dinorchola-5,7-dien-22-al 11:398-402 of 1a,3 ~-diacetoxy-23,24dinorchola-5,7-dien-22-ol 11:398-402 of 1ct,313-diacetoxychola-5,7dien-24-al 11:398-402 of 1c~,313-diacetoxychola-5,7dien-24-ol 11:398-402 of 1c~-hydroxy vitamin D3 10:59 of 1c~-hydroxyvitamin D2 11:381-383 of 1a-hydroxyvitamin D2 ( 1Shydroxycalciol) 11:380,381 of lfl-hydroxyeudesmanolides 24:64 of 1~-hydroxyvitamin D2 11:402-404 of 1[3-hydroxyvitamin D3 11:402-404 of 1[3-methylcarbapenems 12:145-177;13:84 of 2-(c~-hydroxyalkyl) pyrrolidines 12:473 of 2-(e~-hydroxyalkyl) piperidines 12:453-456 of 2,3,4,5-substituted tetrahydrofurans 11:433 of 2,3-dibenzylbutrolactones 24:744-754 of 2,3-unsaturated- 1-thioglycosides 8:346 of 2,6,7-trideox-2,6-imino-Dglycero-D-manno-heptitol 11:467
774
of 2,6,7-trideoxy-2,6-imino-Dglycero-D-gluco-heptitol 11:467 of 22,23-dihydro- 1cx,25dihydroxyvitamin D2 11:395-398 of 24,24-dihomo- 1cc,25dihydroxy vitamin D3 11:385-387 of 24-epi-D2 30:490 of 24-epi-D6 30:490 of 24-epiteasterone 18:515 of 24-epityphasterol 18:515 of 25E,26-hydroxy vitamin O2 10:65,69 of 25-hydroxy vitamin D2 10:69 of 25-hydroxyvitamin D3 11:388-393 of 2-allylphenol 8:169 of 2-amino alcohols 12:411-444 of 2-deoxy-24-epibrassinolide 18:515 of 2-deoxy-2-desmethylene bicylomycin 12:87 of 2-deoxy-3,24-diepibrassinolide 18:515 of 2-flurorostradiol 5:447,449 of 2-hydroxy-6-methylbenzoic acid 9:347,350 of 2-hydroxyindolizidines 12:283,284 of 2-isocephems 12:126,127 of 2-iso-oxacephems 12:128,129 of 2-1ithio-2-phenyl-6-heptene 8:7,8 of 2-methylseleno-2-phenyl 6heptene 8:7 of 3,13-diacetyl-GA3 8:122,123 of 3,13-diacetyl-GA3 phenacyl ester 8:133 of 3,4-dihydroisoquinoline 8:230 of 3,5-disubstituted indolizidine alkaloids 11:245-259 of 30-methyloscillatoxin D 18:294-309 of 3-amino-5-hydroxybenzoic acid 9:434 of 3-cyanocephem derivative 12:135
of 3-dehydro-24-epiteasterone 18:512,513 of 3-dehydroteasterone 18:512, 513 of 3-deoxy- 1~,25-dihydroxy vitamin D3 10:70 of 3-deoxyrosaranolide 11:164 of 3-hydroxy-2-hydroxymethyl6-substituted piperidines 12:474 of 3-nocardinic acid 12:118 of 3-thioxylobiose 8:329 of 4 S-[3-D-galactopyranosyl 4thio-D-galactose 8:339 of 4-acetoxy-[3-1actam 12:160-162 of 4-aryl- 1,2,3,4-tetrahydroisoquinoline derivative 12:451 of 4-aryltetralin-type lignan 18:586-588 of 4-S-D-xylopyranosyl 4-thio-Dxylose 8:338,339 of 4-S-cx-D-glucopyranosyl 4thio-D-glucose 8:331,332 of 4-S-[3-D-galactopyranosyl 4thio-D-glucose 8:335 of 4-S-[3-D-glucopyranosyl 4thio'D-glucose 8:336,337 of 4a-arylisoquinoline ring system 12:457,458 of 5,8-disubstituted indolizidine alkaloids 11:260-267 of 5-acetyl-DIBOA 27:263,204 of 5-amino-7-methoxy-2,2dimethyl chroman 13:358,359 of 5-demethylene-6-deoxybicyclomycin 12:75,76 of 5c~-carbahexopyronoses 13:190-207 of 6(E)-alkylidene-8-hydroxy-8methylindolizidines 12:294,295 of 6(Z)-alkylidene-8-hydroxy-8methylindolizidines 12:295,296 of 6,12-sequiterpenolides 24:53-55 of 6,7,8-trihydroxyindolizidine 12:348 of 6,7-dihydroxyindolizidine 12:348
775
of 6-acetamido-6-deoxycastanosperimine 12:345,346 of 6-deoxy-24-epi-castasterone 18:512,513 of 6-hydroxy-4a-aryl-cisdecahydro- isoquinoline 12:458,459 of 6-hydroxyindolizidines 12:285,286 of 6-S-[3-D-galactopyranosyl 6thio-D-glucose 8:339 of 6-S-[3-D-glucopyranosyl 6thio-D-glucose 8:339 of 7-hydroxy-3-oxoindolizidine 12:287,288 of 7-hydroxy-7-methyl-5oxoindolizidine 12:289 of 7-hydroxyeudesman-6,12olides 24:112 of 7-hydroxyeudesmanes 24:112 of 7-hydroxyindolizidines 12:286-289 of 7-methyl-2-methylseleno-2phenyl-6-octene 8:9,10 of 7-O-ethylrosmanol 29:575 of 7-oxoindolizidine 12:286,287 of 7-thiogibberellin A3 8:123-127 of 8-(3,5-dimethoxyphenyl) octan-l-ol 9:339 of 8,12-elemanolide 24:103,104 of 8,12-sequiterpenolides 24:53, 56,98-107 of 8,14-cedranoxide 8:163-165 of 8-deoxyvernolepin 24:94, 95,98 of 8-geranylapigenin 28:234 of 8-hydroxyindolizidines 12:293 of 9-hydroxyanthracene 11:119 of A-62232 8:400 ofA-65265 8:399,400 ofA-65638 8:400 of abscisic acid 10:167 of acarbose 10:511,515 of acoragermacrone 8:178 of acridin-9-one derivatives 13:353-361 of ACRL toxin 18:178-185
of acyclic amino acids 13:512-516 of acyclic bastadins 10:629-631, 634,635 of adiposin-1 10:514,515 of adiposin-2 10:514,515 ofagelasidine A 28:670 ofagelasidine B 28:670 of agelasphin-9b 18:467-469 of AI-77-B 15:412-418 of aklavinone 11:121,122 of alizarin 26:635-637,642 of alkaloid 223A 29:439 of alkaloids 8:283-292 of allo-aristoteline 11:318-322 of allopumiliotoxins 12:297-300 of alpinolide 23:813 of alstonerine 13:383,408,411, 416,-423 of aluminum borohydride 8:467 ofambrucitin 10:386 of amino acids 11:417; 13:507-516 of amino sugars 13:190-207 of amino-5 a-carba-deoxyhexopyranoses 13:203-207 of aminoacylheptoglycosides 11:433-435 of amphibian alkaloids 29:433 of amylostatin 10:507-509 of amylostatin XG 10:507,510, 511 ofanacardic acids 5:826 of analogs of thapsigargin 24:83 of anisomelic acid 10:13-17 ofantiallergic drugs 29:300 of antisense oligonucleotides 13:264-281 of aopinolide 23:813 ofarbusculin D 24:69 ofarcyriacyanin A 12:382,383 of arcyriaflavin-A 12:376-379 of arcyriaflavin-B 12:379 of arcyriarubin-A 12:375,376 of arcyriarubin-B 12:375,376 of arcyrin/arcyrinin model compounds 12:383 of aristolasicone 11:315-317
776
of aristotelia alkaloids 11:277-334 of aromatic selenoacetals 8:5 of asatone 8:168 of ascocorynin 29:299 ofaspochalasin C 13:131,132, 134 of aspochalasin B 13:142,143 of atisirene 10:180 of avermectins 12:9-33 ofaza analogues 27:207 of aziridinomitosenes 13:444 of azocine 8:207 of baogongteng A 21:751,752 of bastadin-6 10:636-638 ofbenz[a] anthracene antibiotics 11:134-144 of benzalmalonates 9:224,225 of benzyllithuim 8:5 of beryllium borohydride 8:467 ofbicyclo [2.2.2] octanes 8:412-417,419,422,423 ofbicyclo [3.2.2] piperazinedione 12:71 ofbicyclo [5.2.2] piperazinedione 12:84,85 of bicyclohumulenone 8:161-166 of bicyclomycin 12:65-95 of bilobol 9:354 ofbinaphthaleneterol 8:221-223 of bioactive natural products 13:473-518 ofbisabolones 8:39-59 of bis-indolymaleimides 12:375-383 of blood group I active oligosaccharides 10:457-493 of boromycin 10:414 ofbranched amino sugar 10:421 of branched pentasaccharide 10:476,477 of branched tetraacetate 10:476, 477 of branched trisaccharide 10:474-476 of brasilenol 9:249 of brassinosteroids 18:507-520 of bruceantin 11:71-73,79-95 ofbursecan 24:754
of butenolides 11:453 of C18-desmethylcytochalasin D 8:212-217 ofcalamanenenes 15:251 of calichemicin 12:283 of carbacepham 8:262 of carba-disaccharides 13:219-221 of carbapenam 8:262 ofcarba-sugars 13:187-255 of carbocycles 8:410-422 of carbocyclic oxetanocins 10:608-619 of carbohydrates 11:420-422 of carbonolide 11:158-172 of carbonolide A 11:165,166 of carcinogenic adducts 8:373-392 of cardol monoene 9:354 of carotenoids 20:561 of carpanone 8:168 of carpetimycins 12:135 of casbene 8:16,17 of castelanolide 11:74-76 ofcembranes 10:3-42 of cembranoid 8:18-32 of cembranolide 8:16,17 of cembrene 8:15,16 of cembrene diterpenes 8:15,32 of cephalostatins 18:900-902 of cepham derivatives 12:131-133 of C-glycopyranosyl-~-amino acid 11:470-472 of C-glycosides 11:139-144 of chiral allyl boronates 11:393, 394 ofchiral [3-1actams 12:121 of cholesta-5,7-diene- 1c~,3[3,25triol 11:390-393 of chroman 13:359,360 of civetone 8:224 ofcleomeolide 23:488,491 of codeinone 10:180 of conjugated dienes 8:275 of convergent lactone synthon 13:604 of costunolide 8:175-181
777 of coumarinolignan propacin 5:497 of crassin 8:19-32 ofcrassin acetate 10:6,7 of C-sucrose 11:469,470 of cuanzin 8:283-292 of cubitene 8:221,230 of cuparene 8:6 of cuparene analogue 8:6 of cyanocycline A 10:108-115 of cyanohydrin 8:225,226 of cyclaradine 8:148,149 of cyclic amino acids 13:507-512 of cyclodextrins 8:367 of cyclohemiacetals 27:196 of cyclo-L-rhanmohexaose 8:359-370 of cyclooctenone 8:35 of cyclooligosacharides 8:359-370 of cyclopropane derivatives 8:11,12 of cyclosarkomycin 8:150 of cycloundecenones 8:214 of cytochalasin B 10:166; 13:116,117 ofcytochalasin C 13:148,199 ofcytochalasin D 13:134-139 ofcytochalasin G 13:130,131 of cytochalasin H 13:125-129 of cytochalasins 8:213 ofd, l-chaparrinone 11:105,106 of D-allo-c~-amino acid 11:460, 461 ofdecumbenine B 21:735 of dehydroisoerivanin 24:61,62 of dendrobatid alkaloids 11:244-267 of deoxybouvardin 10:640-642 of deoxybouvardin methyl ether 10:640-642 of deoxycubebin 24:754 of desmethoxycuanzine 8:285-292 of des-N-methylnoracronycine 13:355,356 of desoxyasperdiol 10:29,30
of diacetoxybinaphthyl 8:222, 223 of dibenzylbutryrolactone lignans 5:486 of diborane 8:466-468 ofdidemnin-A 10:275,276,281 of didemnin-B 10:276,281 of didemnin-C 10:276,281 of dihydroacarbose 10:508 of dihydromevinolin 13:575, 608,609 of dihydronapthalene 8:402 ofdihydropyrrole 10:112,113 ofdihydroreynosin N 24:65,66 of dihydrosantamarin 24:64-66,77 of dihydrothiopyrone 8:207 of diisopropyl (bromomethyl) boronate 11:425 of diquinanes 13:3-52 of disaccharides 11:469 of diterpenes 29:169 of diterpenes (rumor-promoting) 12:233-274 of d/-camptothecin 12:283 of DNA 8:373-392 of dolaisoleucine 12:477, 483-486 ofdracaenones 5:20,21 of D-(x-aminouronic acid 11:459,460 of ebumamonine 8:264 of elaeocanine 12:454 of eldanolide 11:414 of elemanolides 24:91-98 of enone 8:279 of ent-4-oxo-2,33dihydrosolamin 18:197 of ent-brefeldin A 8:148,149 ofent-rolliniastatin-2 18:208,209 of enyne 8:280 of enzymes 8:315 of epi-corrossoline 18:200 ofepigloeosporone 9:241,242 of epimeric 2,3-epoxy brassinosteroids 18:512 of epipodophyllotoxin 18:597-601 ofepoxyallylic ether 10:589,590
778
of epoxyse squiphellandrene 8:57,58 of equisetin 13:545-547 of eremophilone 10:436,437 of erythromycin A 12:48-54 of erythronolide A 11:152, 11:153,157 ;12:46-54 of erythronolide A seco acid 11:154-156 of ethyl 2-methoxy-6-methylbenzoate 9:345,346 of exo-brevicomin 11:413,414 of flavonoidal alkaloids 21:130 of flexibilene 8:16,17 of freelingyne 10:167 of fruticosonine 11:286 of fukiic acid (phenolic acid) 29:582 of futoenone 8:159 of futoquinol 8:169 ofgalactose prodrugs 21:161 of gangliosides 18:486-488 of GDIBOA 27:188,209 of germacrone 8:178 of gibberellic acid 8:119 of gibberellins 8:115-135 of gibberellins GA4 8:115,119 of gibberellins GAs5 8:119,121 ofgibberellins GAs7 8:121-123 of gibberellins GA60 8:119, 121-123 of gibberellins GAy 8:115,119 of ginkgolic acid 9:355 of glaucambinone 11:79,80,105 ofgloeosporone 9:228,241 of glucuronic prodrugs 21:169 ofglutamic acid 11:419 of glycerol 11:392,393 ofglycosyl ester 8:66 of glyfoline 13:361-367,375-380 of gorgiacerone 23:173 of guainolides 24:80 of guggultetrols 5:707 of guianin 8:159 of haageanolide 8:175-181 ofhelminthosporal 8:162,163 of hernandin 18:579-584 of heteroatom mediated 8:205-217
ofhexalin alcohol 13:601 of hexepi-uvaricin 18:207-216 of higher carbon sugars 11:429-480 ofhobartine derivatives 11:309, 310 of hobartine- 19-ol 11:309 of homothienamycin 8:262 of humulene 8:156 ofhuperzine A 21:746-748 ofhuperzine A from 21:746-748 of hydroazulene 24:80 of hydroxy-amino-acid 12:431-438 of hydroxylated indolizidines 12:263-275 of I-active oligosaccharide containing lactose 10:477-479 of I-active oligosaccharide containing lactose 10:477-479 of Ii-active oligosaccharide containing mannose 10:477-479 of indolizidine alkaloids 11:229-275 of indolo [2,3-a] carbazoles 12:375-383 of ingenol 12:233-345 of inositol phosphates 18:391-451 ofionophore X-14547 A 10:425 of ipsenol 10:188 of isoantibodies 29:542 of isocyanides 12:113 ofisodeoxybouvardin 10:644, 645 of isodeoxybouvardin methyl ether 10:644,645 of isodihydrofutoquinol 8:169, 170 ofisodityrosine 10:630 of isoerivanin 24:61,62 ofisoindolone 8:212 of isoingenol 12:234-245 of isojunenol 24:109 of isolobophytolide 8:205-217; 10:10-13 of isomaltoside 11:469-471 ofisomitomycin A 13:35-37
779
of isopeduncularine 11:284,285 of isoquinoline quinone antibiotics 10:77-145 of isosilybin 5:486 ofjatrophone 10:155,156 ofjunenol 24:109 of K-252c (staurosporinone) 12:379-381 ofketo phosphonate 13:560 of kidamycin aglycone 11:135-139 of klaineanone 11:74-76 oflacto-N-biose I 10:467,468 oflactone synthon 13:615-628 of lactosamine 10:461-467 of L-allo-c~-amino acid 11:460, 461 of large ring compounds 8:19-32 oflasalocid A 10:424 of leucomelone 29:299 ofleukotriene B3 10:159 of leukotriene B4 10:168 oflicochalcone 21:741-743 oflicochalcone 21:741-743 of lignans 18:551-606 of lignarenones A,B 10:167,171 of lithium borohydride 8:467 of LL-Z1271c~ 28:495 of longipinene 8:33,36,37 of 1-oxoeudesma-2,4-dien-11ill-I12,62-olide 24:65,66 of L-ribose 11:390,391 of ludovicin C 24:61,62 of lupeol palmitate (lupeol hexadecanoic acid ester) 29:587 of L-xylo-guggultetrol 5:705-708 of L-xylo-octadecane- 1,2,3,4tetrol 5:707 of lycogalic acid 29:231 of L-c~-aminouronic acid 11:459,460 of la-dihydroxyarbusculin B 24:61,62 of 1a-hydroxyeudesmanolides 24:61,62 of macrocarbocyclic 8:16-18 of macrocycle A 10:280,281
of macrocyclic cytochalasans 13:108-120 of macrocyclic semiochemicals 8:219-256 of macrolide 8:176;10:423 of macrolide antibiotics 12:35-62 of macroline 13:383,411,423, 424 of macroline-related alkaloids 13:383-432 of maesanin 5:821-824 of mannans and oligomers 26:1158 of melicopicine 13:353,354 of methoxybipyrrole aldehyde 8:273 of methyl (2E,4E)-2,4nonadienoate 10:166 of methyl epijasmonate 8:152-157 of methyl jasmonate 8:152-157 of methyl-c~-peracetylhikosaminide 11:449-451 of methynolide 11:158-163 of methyomycin 11:151 ofmevinic acid 13:553-625 of mevinoline 13:605 ofmitomycin A 13:439-442 of mitomycin B 13:439,441 ofmitomycin C 13:440 of mitomycins 13:433-471 of monocyclic [3-1actams 12:120,121 of monosaccharides 13:207-212 of morphine 18:56-98 of mukulol 8:178 of muscone 8:242,243 of mycinolide 11:393,394 ofmyoporone 15:228 of N,N'-dimethyl-4-desmethylene bicyclomycin 12:68-70 of N-acetyllactosamine 10:461-467 ofnagilactone F 28:499 of N-alkyl analogues 8:211 of naphthopyran antibiotics 11:127-133
780
of natural bioactive alkaloids 27:778 of natural bridged biaryls 29:355,356 of natural products 8:175-201, 409-428 of natural steroids 30:504 of N-benzoyl-iso-serinate 12:223,225 of N-benzoylpyrrolinone 8:212 of neolignans 8:159-172 of neopinone 10:180 of nitrosterene 8:230,232 of N-methylcyriaflavin A 12:377-379 of N-methylmaysenine 21:445,446 ofnocardicine A 12:118,119 ofnonactic acid 10:423,424; 18:229-268 ofnonactin 18:260-265 of nonitol 11:464 of nonofuranose 11:458 of nordidemnin-B 10:294-298 of norepinephrine 8:395-406 of octahydroindolizidine-8-ols 12:293 of octahydroindolizine-2-ols 12:283,284 of octahydroindolizine-6-ols 12:285,286 of octahydroindolizine-7-ols 12:286-289 of octa-O-acetyl 1-thio-mannosyl disaccharide 8:320 of octose derivatives 11:462-464 ofOhno's lactone 8:148,149 ofoidiolactone C 28:505 ofoligomeric DNA 8:373 of oligopeptides 10:629-669 of oligosaccharides 8:316 of oligostatins 10:516 of O-methylancistrocladine 8:228,229 of oscillatoxin D 18:269-309 of otonecine 8:211 ofoxetanocin A 10:587-608 of oxetanocins 10:585-627
of oxetanosyl chloride 10:604- 607 of oxycyclopropane 8:34,35 of pantolactone homologue 10:442,443 ofpapaveraldine 8:263 ofparaherquamides 28:331,332 of penam carboxylic acid 12:127-129 ofpenems 8:262 of penicillin derivatives 12:129-131 ofpenicillins 12:115,116 of pentacenequinone 11:121,122 of pentacyclic diterpenoids 8:418 of pentalenene 13:6-8 of pepstatin 12:476 of periplanone B 8:156, 179-182,226,227 of permethyl cyclohexanone 8:4,5 of permethyl cyclopentanone 8:4,5 of persoonol dimethylether 9:355 of petrosterol 9:37 ofpeudolaric acid B 21:757 of phenolic lipids 9:343-369 of phenylalanine 11:417,418 of phenyllactate 12:223 of pheromones 9:351 of phorbol 12:245-272 of phosphatidyl inositols 18:445- 450 of phosphoramidite 8:388,389 of phosphorylated polprenols 8:64,65 ofphosphotriesters 13:272,273 of phyllanthocin 8:280 of phytosphingolipids 18:457-490 of picrotoxinin 8:279 of pikronolide 11:158-163 of piperazinomycin 10:638-640 ofpodolactones 28:495 of podophyllotoxin 18:597-601 of polene synthons 20:571,573 ofpolycarpamine A 28:640
781 ofpolycarpamine C 28:640 ofpolycycles 8:278 of polycyclic aromatic compounds 11:119-127 of polyhydroxy-p-terphenyls 29:298 of polyhydroxyterphenyls 29:300 of poly-N-acetyllactosamine 10:323 ofpolyporic acid 29:298 of polyprenyl diphosphates 8:65,68,69,81 of polyprenyl monophosphates 8:65,68,69,82 of polysiloxanes 13:328 ofporfiromycin 13:440 ofprezizanol 15:248 of protein 8:315 of proxiphomin 13:122,123 of pseudo-disaccharides 13:212-216 ofpseudolaric acid B 21:757 ofpseudomonic acid 10:425 of pseudo-NANA 13:210 of pseudo-oligosaccharides 13:235-246 of pseudopterosins 23:154,158, 180 of pseudo-trisaccharides 13:212-216 ofp-terphenylquinones 29:299 of ptilostemonol 8:45,47 ofptilostemonol acetate 8:47 of pumiliotoxin 12:294,296 ofpumiliotoxin 251D 12:294, 295 metabolism 5:449 ofpyrazines 5:254 ofpyrrole formation 8:269 of quassimarin 11:79,80 of quassin 11:73-76 of quassinoids 11:1-111 of quaternary carbons 8:3-14 of quinocarcin 10:125-141 of quinocarcinol 10:120-124 ofR (-)-muscone 8:224,225 of R-(+)-p-carvomenthene 8:49 ofracemic acerolide 23:176
ofracemic compactin 13:562, 563 of recifeiolide 8:176 of renieramycin A 10:97-100 ofretinoic acid 30:493 ofrifamycin S 12:37,38 ofrifamycin W 12:39-47 ofritterazine K 18:900-902 of RNA 13:284,285 of rosaranolide 11:164 of saframycin A 10:84-87,92-96 ofsaframycin B 10:88-93 ofsaframycins 10:83-100 of sarcophytol B 8:18,19 of sarmentosin 21:739,740 of sarmentosin 21:739,740 of scopadulane-type diterpenoids 21:706 of secasterone 18:512 of seco-taxane 12:179,180,201 of serine 11: 420 of serotonin 30:370 of sesquiterpenes 24:53-125, 175-513 of shikimic acid 13:188 of sildydianin 8:166,167 of silphinene 8:165,166 of silybin 5:486 of sinefungin 11:437,438 of siozonarol 24:188-190 of sodium trimethoxyborohydride 8:467 of sopadulan- type diterpenoids 21:706-717 of sorelline 11:326,327 ofspirocyclic core 21:391 ofspirocyclic core 21:391 of spiroethers 18:269-309 ofspiromentins B 29:300 of steganone 24:779,780 of sterepolide 8:280 of steroid 8:167-174 of steroid moiety 30:486 of suaveoline 13:383,408, 411-417 of supensolide 8:222,234,236 of swinholide A 18:178-185 oftalcarpine 13:383,411, 424-426
782
of tautomycin 18:269-309 of taxane 11:3-69;12:181-216 of taxol 12:217-221 of taxusin 11:55-59;12:200,221 of terpenes 8:33-37 of terpenoid alkaloids 8:418 of terphenylquinones 29:298,299 of terprenin 29:300 of tetracyclic diterpenoids 8:418 of tetrahydrofuran derivatives 24:754,755 of tetramethoxyturriane 8:228, 229 of tetraoxoalkanedioates 11:117 of tetrols 5:708 ofthelephoric acid 29:298 of thiodisaccharides 8:316-330, 339,342,343,346 of thiolactone 8:205-207 of thiooligosaccharides 8:316, 317-330 of thiotrisaccharides 8:340 of threo-(4S,5S)-4-benzylamino5-hydroxy-2-methyl-6phenylhex- 1-ene 12:478,479 of thromboxane B2 10:419 ofthymosin or1 8:437-446 ofthymosin oti~ 8:447 ofthymosin [34 8:447-453 of thymosins 8:437-454 ofthymosins B8 8:456,457 oftjipanazole D 12:382 oftjipanazole E 12:382 of trans-7-formyloxy-8amethylindolizidine 12:288 of trans-hydrindane 10:51 oftricarbonyls 8:261-274 of triplolide 23:686 of triquinane terpenes 10:426-428 of triquinanes 13:3-52 of tunicamycins 11:446-449 of uranium (iv) borohydride 8:467 of urdamycinone B 11:134,135, 142-144 of uridine diphosphate-galactose 10:468
of validamine 13:190 of validamycin A-H 13:228-232 of valienamine 10:507;13:199 of valine 11:418,419 of valiolamine 13:201 of vancomycin 10:661-669 of verrucarol 10:426-428 of verticillene 12:182,183 of villalstonine 13:405 of vinblastine 14:805-884 of vincristine 14:805-884 of vinylsilanes 8:242,243 of vitamin D 11:379-408 of vitamin D aldehyde 10:52 of vitamin D analogues 30:485-494 of vitamin D derivatives 30:491 of vitamin D2 30:490 of vitamin D3 30:490,493 of vitamin D4 30:490 of vitamin D5 30:490 of vitamin D7 30:490 of xylerythrins 29:299 of xylosides 8:362 of yomogin 24:104-106 of Z,Z- 1,4-dienic macrolides 8:242 of zearalenone 13:536-543 of zeralenone 8:176,177 of zonarol 24:188-190 ofzygosporin E 13:146,147 of Z-[3-7-unsaturated macrolide 8:222,232 of Z-y-unsaturated carboxylic acids 8:239 of AS'7-unsaturated brassinosteroids 18:515-520 of AL7-oxygenated brassinosteroid 18:515-520 of Ag(12)-capnellene 13:34,35 of A-benzyl- 1,2,3,4-tetrahydroisoquinolone alkaloids 10:683-685 of o~(1--+4)-linked 4,4'dithiotrisaccharides 8:344,345 of o~-l,4-disaccharide 8:369 of a-amino acid 12:435-438 of o~-copaene 8:33-36
783 of c~-cyclodextrins 8:367,368 of ct-D-fructofuranosyl- 1-thio-[3D-glucopyranoside 8:325,327 of (x-dicarbonyls 8:261-274 of ct-enamino derivative 8:262 of ct-halomethylcycloheptane 8:35-37 of (x-hydroxy- [3-amino acid 12:493 of (x-longipinene 8:33,36,37 of (x-mono-alkoxylated piperzinediones 12:84 of [3 (1--~4) linked 4,4'dithiotrisaccharides 8:347,349 of [3,[3-trehalose 8:317,318 of 13-copaene 8:33-36 of [3-galactosidase 8:315,316 of [3-hydroxy ester 11:395 of [3-hydroxy macrolides 8:231,232 of J3-1ongipinene 8:33,36,37 of [3-necrodol 8:279 of ~-sesquiphellandrene 8:45, 46,51,55 of D-turmerone 8:51,52 of ),-allenyl-GABA 13:514 of?-aminobutyric acid (GABA) 13:514 of ?-dehydro-cz-amino acid 11:471,472 of c~,(x-disubstituted 3piperidinol alkaloids 29:421 reaction with lead tetraacetate 5:21 reaction with tristrifluoroacetate (TTFA) 5:21 via phenolic oxidative coupling 5:21 Synthetase 7:123 Synthetic access 27:185-225 to benzoxazinones 27:185-225 Synthetic acronycine 20:789 Synthetic analogues 29:359 of allocolchicinoids 29:359 Synthetic approaches 4:120;14:805884;20:899-902
of microcystins 20:899-902 of nodularins 20:899-902 to 6-epi-purpurosaine B 4:120 to purpurosamine B 4:120 to vinblastine 14:805-884 to vincristine 14:805-884 Synthetic consonance 3:4 Synthetic derivatives 26:162;29:246 of acetylsalicylic acid 26:162 of 4[~-aminoaniline 26:162 of 2-aminobenzothiazole 26:162 of 2-mercaptobenzothiazole 26:162 Synthetic dissonance 3:4 Synthetic ecdysteroid analogues 29:19 11ct-acyl turkesterone as 29:19 dacryhainansterone as 29:19 2-(4,5-dimethoxy-2-nitrobenzyl)20-hydroxyecdysone as 29:19 25-fluoroponasterone A 29:19 26-iodoponasterone A as 29:19 Synthetic fuorinated compounds 29:344 5-fluoro-6-fluoro-substituted alkaloids as 29:344 5-fluoro-Nb-acetyltryptamine as 29:344 5-fluoro-[3-hydroxy-Nb-acetyltryptamine as 29:344 6-fluoro-[3-hydroxy-Nb-acetyltryptamine as 29:344 fluorotryptamines as 29:344 Synthetic methods 20:294-307 of biaryls 20:294-307 of diarylethers 20:307 Synthetic peptide 18:920-926 Synthetic pharmacological agents 30:224 antioxidant activity of 30:224 Synthetic podolactones 28:484 allelopathic activity of 28:484 Synthetic psychotropic agents 24:1093 Synthetic reagents 6:307-349 dithioacetal S-oxides as 6:307349 dithioacetal S,S-dioxides as 6:307-349
784
Synthetic routes 29:227 to arcyriaoxocin A 29:227 Synthetic strategies 29:128,129,130,452 for carbaaldofuranoses 29:452 of kuehneromycin A 29:128, 129,130 Synthetic studies 15:493-500 of humantenine-type oxindole alkaloids 15:493-500 of koumine-type alkaloids 15:500-503 of sarpagine-type alkaloids 15:487-493 Synthetic substrate analogues 7:29-86 in enzyme-carbohydrate interactions 7:29-86 Synthon 22:218 Syringa 26:327 Syringaldehyde 18:569;23:798 Syringaresinol 5:475,476;24:741 anti-platelet aggregation activity of 24:741 (-)-Syringaresinol 26:243 as PAF-induced inhibitor 26:243 (+)-Syringaresinol 26:267,270 (+)-Syringaresinol 5:524,526,530; 26:200 O-glucosylation of 5:525 O-methylation of 5:525 (-)-Syringaresinol diacetate 26:200 (+)-Syringaresinol dimethyl ether 5:526;26:200 (-)-Syringaresinol di-[3-D-glucoside 5:524;26:200 (+)-Syringaresinol di-[3-D-glucoside 26:200 Syringaresinol-[3-syringaresinol ether 4,4'-di-O-[3-D-glucopyranoside 20:700 Syringic acid 23:750,798 Syringin 5:471 Syringyl subunits 25:653 Syringylglycerol-[3-sinapyl alcohol ether di-p-hydroxy-benzoate 20:636 Syringylglycerol- [3-syringaresinol ether glycoside 20:700 System resonance 3:46
Systemic acquired resistance (SAR) 25:40,394 Systemic wound response protein 25:402 Systemin 25:85,371,374,375,377,380 derivative 25:389 Systemin (II) 25:370 Systemin activity 25:373 assay for 25:373 Systemin maturation 25:376 Systemin oligopeptide 25:371 Systemin polypeptide 25:371 Systemin signal 25:374 Systemin-triggered changes 25:374 Syzygium carynocarpum 29:708 Syzygium malaccense 29:708 T and B-cell epitope chimeras 18:929,930 T-2 toxin 9:28,210;13:522 from Fusarium sporotrichioides 13:522 T-2 Toxin analogues 6:242 T4 polynucleotide kinase 13:289 T7 RNApolymerase 13:284 Tabarin 7:232 Tabebuia avellanadae 5:16;15:385; 27:851 Tabernaelegantine-A 5:128 Tabernaelegantine-B 5:128,129 Tabernaelegantine-C 5:128 Tabernaelegantine-D 5:128 Tabernaelegantinine-A 5:129 Tabernaelegantinine-B 5:129 Tabernaemontana ciliata 5:83 Tabernaemontana divaricata 9:166-168 Tabernaemontana eglandulosa 5:109 Tabernaemontana orientalis 5:70 Tabernaemontana pachysiphon 5:110 Tabernaemontana rigida 5:107 Tabernaemontana sp. 5:69-70,83,84, 86,89,93;9:164,165 indole alkaloids from 5:69-134 Tabernaemontana spp. 22:533 Tabernaemontaninol 5:125 Tabernaemontine 5:112,125 Tabernamine 5:129 Tabernanthe iboga 22:533
785 Tabernanthine 5:124;25:533 as immunosuppressive drug 25:533 Tabernulosine 5:126 ~-Tabersonine 14:833 synthesis of 14:847 Tabersonine 5:124;9:190;19:90 biosynthesis of 4:616 from Amsonia tabernaemontana 19:90 synthesis of 19:103 (-)-Tabersonine 4:35 conversion to vindoline analogues 4:35 enantioselective synthesis 4:41,42 hydroxylation of 4:35 Tabidi 17:200 Tabotoxin 4:582 synthesis of 4:582 Tabtoxinine 26:372 Tacamine 1:114;9:179,180 16-epi-Tacamine 5:127 16R-Tacamine 5:127 Tacamine-type alkaloids 5:109,110 16,17-anhydrotacamine 5:109,110 16R-decarbomethoxytacamine 5:109 19S-hydroxytacamine 5:110 17-hydroxytacamonine 5:109 tacamine (16R) 5:110 tacamine (165) 5:110 16-epi-tacamonine 5:109 Tacamin-type alkaloids 5:71 Tacamonine 5:109,126;9:180,181 Tachykinin 9:318 Tachykinins 27:798 of substances P 27:798 of substances K 27:798 of neuropeptides 27:798 Tachytes guatemalensis 5:223,253 Tacraline 5:125 Tageretin 26:746,752,758 Tagetes erecta 21:600 Tagetesfilicifolia Lag. 21:618;27:16 trans-anethole from 27:16 Tagetes sp. 26:437 (E)-Tagetone 21:613
(Z)-Tagetone 21:613 Tagetone 25:143,144 Tail flick test 30:802,810 for determination of antinociception 30:802 ofdeltorphin II 30:810 of DTAOH+DEL II 30:810 of DTOH+DEL II 30:810 Taiwania cryptomeriodes 17:333; 26:232;28:418 helioxanthin from 26:232 Taiwanian E 26:194,243 methyl ether of 26:194,243 Taiwanin E 26:243 as PAF-induced inhibitor 26:243 Taka-amylase (endo-glucanase) 7:34,35 maltotetraoses from 7:34,35 Takai reaction 30:38,41 Takai's homologation 26:1224 Takano's reaction 12:26,27 of enoate 12:26,27 with cyclopentadiene 12:26,27 Takano's synthesis 14:865-867 of vinblastine 14:865-867 of vincristine 14:865-867 Talarommycin A 3:262,264 synthesis of 3:262,264 Talaromyces flavus 21:239 Talaromyces stipitatus 14:531 talaromycin A and B from 14:531 Talaromyces wortmannii 27:858 Talaromycin A 1:700,701;14:531539;19:128 synthesis of 1:700,701;14:531539 via Evans asymmetric induction procedure 14:531 via asymmetric reductions of ~keto esters 14:533,534 via [2,3] sigmatropic rearrangement 14:533,534 Talaromycin A,B 3:262;14:531-539 asymmetric synthesis of 14:531 539 synthesis of 3:262 (-)-Talaromycin B 14:538,539 synthesis of 14:538,539
786 Talcarpine 5:83,125;13:383385,388,391,397-399,411,423-426 from ajmaline 13:424-426 synthesis of 13:383,411,424-426 epi-Talcarpine 5:83,127 Talekin derivatives 7:233 Talin protein 27:9,10 as sweetner 27:9,10 Talinum tenuissimum 7:427,435 Talisopine 534,542 L-Talitol 4:505 advantages of 4:505 D-Talopyranose 6:360 C4-P bond analogs of 6:360 L-Talopyranoside 6:360 C4-P bond analogs of 6:360 Talpinine 13:388,389,391,397-399 Tamao oxidation 19:536 (-)-Tamariscol 18:625 from Frullania tamarisci 18:614-624 Tamariscol 9:255 from Frullania tamarisci 9:254 oxidation of 9:254,255 Tamarix articulata 22:533 for epilepsy 22:533 Tamarix gallica L. 22:533 for epilepsy 22:533 Tamaulipin A 7:231 from Artemisia hispanica 7:211 Tambjamines 17:89,94,105 A,B,C & D 17:89 E & F 17:94 Tamine 26:965 Tamirin 27:568 Tammariscol 2:278,279 Tamoxifen 20:515;26:222 Tamus communis 17:130,132 TAN-1030A 12:366,367 from Streptomyces sp. C-71799 12:366,367 NOE experiment of 12:367 TAN-420 23:54 TAN-999 12:366,367 from Nocardiopsis dassonvillei 12:366,367 Tanacetin 27:556 Tanacetol A 27:574 Tanacetol B 27:574
Tanacetrum vulgare 7:94,95,98,101, 102,108,109,112,120 Tanacetum albipannosum 27:570,590 Tanacetum annuum 27:575 Tanacetum argenteum 27:551,565,579 Tanacetum argyrophyllum 27:555 Tanacetum aucheranum 27:586,587 Tanacetum balsamita 27:551,591 Tanacetum chiliophyllum 27:551,556 Tanacetum cilicium 27:575 Tanacetum cinerariaefolium 27:551, 571 Tanacetum corymbosum 27:586 Tanacetum densum 27:551 Tanacetum ferulaceum 27:549 Tanacetum heterotomum 27:590 Tanacetum indicum 27:575 Tanacetum microphyllum 27:564,574; 29:89,703 Tanacetum odessanum 27:586 Tanacetum parthenifolium 27:581 Tanacetum parthenium 7:119,120; 24:849;27:548,566,856;29:88,686,70 3;30:206 active anti-migrane principle in 24:849 in treatment of migraine 30:206 Tanacetum poteriifolium 27:560 Tanacetum praeteritum 27:549 Tanacetum pseudoachillea 27:557 Tanacetum ptarmicaeflorum 27:558, 567 Tanacetum santolina 27:550,555,566 Tanacetum santolinoide 27:551,567 Tanacetum serotinum 27:550 Tanacetum sinaicum 27:553 Tanacetum sp. 27:634,547 allergent activity of 27:634 anticoagulant and antifibrinolytic activity of 27:635 antihelmintic activity of 27:636 antiinflammatory activity of 27:637 antiulcer activity of 27:639 biological activities of 27:547 cytotoxic effects of 27:639 insecticidal activity of 27:641 phytochemical studies of 27:548-594
787
phytotoxic activity of 27:643 prophylactic activity against migraine 27:643 Tanacetum tanacetioides 27:555 Tanacetum vulgare 11:221 ;27:548,549; 28:426;29:703 extracts 28:427 acaricidal activity of 28:427 Tanachin 27:569 (+)-Tanakamine 9:178 (+)-Tanakine 9:178 Tanalbin A 27:570 Tanalbin B 27:570 Tanaparthin derivatives 7:236,237 Tanaparthin-c~-peroxide 27:582 Tanaparthin- 13-peroxide 27:582 seco-Tanapartholide 27:585 Tanaphillin 27:586 Tanapraetinolide 27:556 Tanapsin 27:557 Tanargyrolide 27:570 iso-Tanargyrolide 27:570 Tanavulgarol 27:593 Tanciloide 27:583 iso-Tanciloide 27:583 Tanciloide 8a-methylbutyrate 27:583 Tandem conjugate addition 24:745,746, 758,771 Tandem Grignard reaction 19:11 Tandem mass spectrometry (FABMS/MS) 9:468,487-507 of peptides-protein 9:468,487507 Tandem Michael addition 4:556,557 with Cu (I)-tributylphosphine 4:556,557 Tandem Michael-aldol reaction 3:138143 Tandem process (two-stage coupling process) 12:55-58 mechanistic consideration of 12:55-58 Tangeretin (5,6,7,8,4'-pentahydroxyflavone) 23:747;29:573 effects on HIV- 1 protease 29:573 Tangeretin (5,6,7,8,4'-pentamethoxyflavone) 7:413
TANGO sequence 9:97,98 Tangulic acid 7:133 from Barringtonia acutangula 7:132 Tangutorine 25:20,21,33 Tanichthys alobonubes 25:794 Tannic acids 28:280 structure of 28:280 Tannin-derivatives 22:609 Tannins 7:194,426,427;20:16;23:395, 420,442,445;24:510-521 ;27:413,416 as antiviral compound 24:510521 biological activity of 27:413,416 molluscicidal activity of 7:427 Tannunolide A 27:583 Tannunolide B 27:584 Tannunolide C 27:584 Tannunolide D 27:584 Tannunolide E 27:584 Tansanin 27:570 Tanshinone I and II 22:175 Tanshione I 29:100 activity in AM assay system 29:100 Taondiol 6:54 from Taonia atomaria 6:54 (+)-Taondiol 6:56 synthesis of 6:56 Taondiol methyl ether 6:56 biomimetic synthesis of 6:56 from all-trans-geranylgeraniol 6:56 Taonia atomaria 6:54;21:275;25:249 taondiol from 6:54 Tar cancer 7:8 Tararomycin stipitatus 3:262 Taraxacum officinale Wigg. 27:215; 28:424;29:586 allelopathic interaction of 27:215 Taraxastanes 25:59,64 faradiol 25:61 heliantriole 25:61 Taraxastene triterpenes 22:104 w-Taraxastene triterpenes 22:104 A2~ 25:57 qJ-Taraxasterol 22:109;23:535 64 ~-Taraxasterol 25:57,58,59,
788 Taraxasterol 9:267;27:591 from Salvia pomifera 20:702 Taraxerane 23:692;25:59 Taraxerane derivatives 7:144,145 Taraxerol (taraxer- 14-en-313-ol) 7:189; 29:588 effects on TRY 29:588 Taraxerone 7:161,162 oxidation of 7:161,162 Taraxeryl cis-p-hydroxycinnamate 7:189 Target-oriented (linear) synthesis 29:452 carbaaldofuranoses 29:452 Targionia hypophylla 2:278 Taricha torosa 18:724 Taridin A-C 7:231 (R,R)-Tartaric acid 12:295
(3R,4R)-3,4-bis-(benzyloxy) succinic anhydride from 12:295 1,2-dihydroxy-hexahydro-3 (2H)indolizidines 12:295 D,L-Tartaric acid 6:315 R,S-4-hydrocyclopentenones from 6:315 L-Tartaric acid 14:568 pyrrolidine from 14:568 L-(+)-Tartaric acid 21:200 Tartaric acid 7:180 in mangrove plants 7:180 (R,R)-Tartaric acid salt 11:289 of (S)-c~-terpinylamine 11:289 recrystallization of 11:289 Tartaric conjugates 28:262 in coffee 28:262 Tashiromine 15:523 from Maackia tashiroi 15:523 (+)-Tashiromine 18:353 synthesis of 18:353 Tasmanin 9:196 Taspine 22:361 Taste principles 2:278-280 hot and bitter 2:278-280 liverwort 2:278-280 Taste receptors 29:42 Tathy lyncurium 25:718 Tatraclinis articulata 25:246 Tatridin A 27:571
Tatridin B 27:571 Taurin 7:183,184,186,232;17:90; 25:536,537,872,873 Tauroacidin A 25:713,798,870 Tauroacidin B 25:713,798,870 Taurookadaic acid 5:385,388 Tauropine dehydrogenases 25:718 Tauropinnaic acid 25:871 ;28:657 as phospholipase A2 inhibitor 28:657; stereochemistry of 28:657 Taurospongin A 23:212,213; 25:721,871 ;28:690 acetylene acids of 23:212 as DNA polymerase inhibitor 28:690 as HIV reverse transcriptase inhibitor 28:690 as sulfated acetylenic fatty acid derivative 28:690 Tautomeric forms 4:724,725 ofascorbic acid 4:724,725 Tautomerism 14:100;23:36 in tetramic acids 14:100 in SAMM 1 23:36 in SAMM 2 23:36 Tautomerization 27:771 of MO4 27:771 Tautomycin 18:269-309 synthesis of 18:269-309 from Streptomyces spiroverticillatus 18:269 Taveniera abyssinica 26:473 Tawicyclamide A 25:883 Tawicyclamide B 25:883 Taxaceae 7:416;11:3;25:244;26:185 Taxagifine 11:5;20:81 Taxamairins A and B 20:118 Taxane 11:4-6 biological activity of 11:4-6 relative stereochemistry of 12:191,195 synthesis of 11:3-69;12:181-216 Taxane derivatives 20:80,107 Taxane diterpenes 12:179-231 chemical studies of 12:179-231 synthesis of 3:100-110 Taxchinine A and B 20:101
789
Taxifolin (dihydroflavonol) 22:323,326; 29:583 effects on MMP 29:583 Taxifolin 3- O-c~-L-rhamnopyranoside 28:64 anti-oxidant activity of 28:64 Taxine A and B 20:80 Taxinine 11:4;12:179,208-210 Taxiresinol 20:107 from 7". paccata 20:108 Taxisol 28:559 as anticancer drug 28:559 Taxodiaceae 25:249;26:185 Taxodione 19:405,20:712 Banerjee and Carrasco synthesis of 14:695-699 biological activity of 14:667 Burnell synthesis of 14:685,687689 Engler synthesis of 14:692-695 from abietatriene-7-one 14:685,687-689 from abietic acid 14:67274,676,677,689-692 from [3-cyclocitrol 14:673-676 from dimethoxy benzene 14:670-74,681,682 from ferruginol 689,690 from isopropylcatechol 14:684686 from 2-methoxy-3-isopropyl- 1,4benzoquinone 14:692-695 from podocarpic acid 14:667670 from Salvia montbretti 20:666 from Taxodium distichum 14:667 Haslinger and Michael synthesis of 14:692-695 Johnson synthesis of 14:681-684 Matsumoto synthesis of 14:670676 Mori-Matsui synthesis of 14:667-670 Stevens and Bisacchi synthesis of 14:684-686 synthesis of 3:436;14:667702;19: 405,20: 712 ;24:202-206 Watt synthesis of 14:681-684
Taxodium distichum 14:667 taxodione from 14:667 Taxoids 24:933 mass spectral analysis of 24:933, 934 Taxol 11:3:12:179,180;21:96;22:217, 218 ;23:490;24:269,271,276,405,933972;25:244,245;26:753,811,812,828, 830;27:857;30:5 absolute configuration of 11:3 antitumor activity of 12:180 as microtubule stabilizing agent 30 biological activity of 12:179,180 de novo synthesis of 24:933 for treatment of ovarian cancer 24:933 for treatment of refractory breast cancer 24:933 from Taxus brevifolia 11:5 ;12:180;13:654 partial synthesis of 12:208,210 structure of 24:405 structure-activity profile of 12:220,221 synthesis of 13:654 Taxol C and D 20:81 Taxol-resistant breast cancer 30:5 clinical development for 30:5 chemotherapeutic agent for 30:5 Taxol-resistant colon cell 30:5 Taxol-resistant ovarian cell 30:5 Taxopneustes pileolus 7:283-285 Taxotere 25:245;12:179,180 biological activity of 12:179,180 X-Ray crystallography in analysis of 12:225 Taxus baccata 11:61,20,79,80, 112,116,118;22:533;25:245 10-deacetylbaccatin III from 11:61 abscessic acid from 10:118 betuloside from 20:111 escholtzxanthine from 20:118 for epilepsy 22:533 isotaxiresinol from 20:108 secoisolariciresinol from 20:108 taxiresinol from 20:108 taxicatin from 20:116
790
Taxus brevifolia 7:416;11:5 ;12:180; 20:140;22:717 ;24:269;25:244,245; 26:112 brevitaxin from 26:212 diterpenes of 7:416 taxol from 11:5,12:180 Taxus canadensis 20:107 canadensiene from 20:107 Taxus chinensis 20:107 Taxus cuspidata 20:80 Taxus cuspidata var. nana 24:276,278 Taxus floridata 20:81 Taxus mariei 20:108 c~-conidendrine from 20:108 kojic acid from 20:118 Taxus media 20:81 Taxus sp. 20:79-123;24:270-276 chemical constituents of 20:79-123 Taxus wallichiana 20:107;22:533 wallifoliol from 20:107 Taxusin 11:55-59;12:200,201;16:151 synthesis of 11:55-59;12:200, 201;16:151 (-)-Taylorione 16:259 Tazettine 20:325,353,370,385; 26:614,618 Tazetting 4:17 TBDMS (Tert-butyldimethylsilyl chloride)283 TBDMSCi protection 4:388,389 in (+)- 5- O-methyllicoricidin synthesis 4:388,389 O-TBDPS lactaldehyde 18:164 TCDD (2,3,7,8-tetrachlorodibenzo-pdioxin) receptor 1:5 T-cell activation 25:463 T-cell mediated cytotoxicity 25:466 T-cell mediated liver injury 25:463 T-cell stimulation 23:129 T-cell subsets 25:442 antitumor-effect of 25:442 ),6-T-cells 30:766,768 in CVE-administered mice 30:768 in protection after listerial infection 30:766 Tchitatine 20:676 from Salvia tchihatcheffii 20:676
TDP glucose oxidoreductase 11:214216 TDP-4-oxo-6-deoxy-D-glucose by 11:214,215 TDP-4-oxo-6-deoxy-D-glucose 11:214,215 by TDP glucose oxidoreductase 11:214,215 from TDP-D-glucose 11:214,215 (6S)-TDP-D-[4-2H1, 6-3H] glucose 11:214 (6R)-TDP-D-[4-2H1, 6-3H] glucose 11:214 TDP-D-glucose 11:214,215 by TDP glucose oxidoreductase 11:214,215 TDP-4-oxo-6-deoxy-D-glucose from 11:214,:215 Te 125 9:109-126 natural abundance of 9:110 receptivity of 9:110 resonance frequency of 9:110 spin quantum number of 9:110 Te 125NMR 9:123,124 of phenyl cyclohexyl telluride 9:123,124 Tea 30:80 effect on lipids (total cholesterol triglyceride) 30:80 Tea saponin 30:84,86 effect on pancreatic lipase activity 30:86 effect on parametrial adipose weight 30:85 effect on triacylglycerol contents 30:84 Tea tannins 25:44 Tea tree (Melaleuca alternifolia) 28:415 activity against Psoroptes cuniculi 28:415 Teasteron 3-myristale 18:495,500 from Lilium longiflorum 18:495 Teasterone 16:324,334;18:500,512,520; 25:415,421,422 from cyclosterol 16:324,334 Tebbe olefination 3:270 Tebbe reagent 14:119;16:226;24:12,I9
791
Tebbe rearrangemet 6:46,47 in (+)-A9(~2)-capnellene synthesis 6:46,47 Tebebuia chrysantha 4:388 naphthopyrans from 4:388 Tebuquine 25:344 Techniques 7:89-96 of plant tissue culture 7:89-96 Teclea natalensis 13:348,350 Tecleanthine 13:348,350 from Teclea natalensis 13:348,350 Tecoma araliaceae 29:722 Tecoma stans 26:1010 Tecomoside 7:440,455 Tecona grandis 4:388 naphthopyrons from 4:388 Tectoquinone 26:665 Tectorigenin 22:473 Tedania ignis 19:558;25:814,828,896 Tedanolides 19:558-566 Teferidine 5:722,723 Teferin 5:722,723 Tegolophus australis 28:423 Tehuacana 22:571 Teleocidin 10:4 Teleocidin A 2:286 Teleocidin B 25:59,65 Teleogryllus commodus 5:815,830,831 Telesto riisei 1:687 punaglandin from 1:687 Tellimagrandin II (eugenin) 23:401 ; 26:359,372 Telocidines 11:278 from Streptomyces mediocidicum 11:278 Telomer 8:224 Telomerizations 12:416;21:387 Temisin 7:237 Template selectivity 1:608 Temuconine 26:824,825,827 Ten-carbon sugars 4:182-187 by epoxide route 4:182-187 by osmylation 4:182-187 Tenebrio molitor 22:386,393 Teniposide 5:461,462;13:654;20:458; 26:160,163,212,213 Tenuazonic acid 28:114 analogues of 28:115
antibacterial activity of 28:115 antiviral activity of 28:115 as growth inhibitor 28:115 for peptide inhibition 28:115 Tenuifolin B 28:229 biological activity of 28:229 Tenuiorin 20:471,472 Tenuispinoside A, B, C 15:51,52 Tenulin 20:10 Tephrosia luninifolia 29:785 Tephrosin 28:436 as complex I inhibitor 28:436, 437 Teratogenic agents 23:563 Teratogenic metabolites 7:21-24 of steroidal amines 7:21-24 Teratogenic potencies 23:575 of steroidal alkaloids 23:575 Teratogenicity 7:19-22,24;23:576, 577,584 ofjervanes 23:576,577,584 of solanidanes 23:576,577,584 of spirosolanes 23:576,577 Terbinafine 22:61 Terbutylstannyl)-D-glycal 10:3441-( Terferol 29:265 as acetylcholinesterase (AchE) inhibitor 29:265 bearing oxygenated functions 29:265 Tergalloyl group 23:415 Terihanine 27:160 6-oxoderivative of 27:160 Termilignan 26:224,225,228,231 Terminal acetylene 27:348 oxidation of 27:348 5'-Terminal guanylic acid 14:283 cyclization of 14:283 via 2'-5'phosphodiester 14:283 Terminalia alata 7:134 arjunolic acid from 7:134 maslinic acid from 7:134 maslinic lactone from 7:134 oleanolic acid from 7:134 terminolic acid from 7:134 Terminalia arjuna 7:133 arjunosides I-IV from 7:133 terminic acid from 7:133 terminoic acid from 7:133
792
Terminalia bellerica 26:228,231 anolignan B from 26:224,231 termilignan from 26:224,231 thannilignan from 26:224 Terminalia chebula 22:533 for epilepsy 22:533 Terminalia genera 27:755 Terminalia siricia 7:132 siricic acid methyl ester from 7:132 Terminalia tomentosa 7:134;23:515 Terminalis sp. 7:133-135 triterpenes of 7:133-135 Terminoic acid 7:134 from Terminalia arjuna 7:133 Terminolic acid 7:135 from Terminalia alata 7:134 Termite soldiers 14:451 defensive secretion of 14:451 Termitinae 8:220 Ternary complexes 9:563,567,569571,575 Ternifolin 15:140 from Rabdosia ternifolia 15:175 IH-NMR of 15:148 Terpene acid 5:756 Terpene isothiocyanates 25:847 Terpene metabolism 7:108-110 Terpenes 5:403;7:208-219;8:219;17:4, 15,613,642;21:599;24:510521;29:74,76 anti-inflammatory activities of 29:74,81 anti-mutagenic activity of 29:76 apoptosis induction by 29:76 as antihealants 14:451 as glues 14:451 as irritants 14:451 as repellents 14:451 bioactives of 29:74 chemopreventive activities of 29:74,81 classes of 29:74 ear edema inhibition by 29:76 effects on 5-1ipoxygenaseenzyme 29:76 effects on 7,12-dimethylbenz [a] anthracene (DMBA) induced mammary tumors 29:76
effects on activated protein 1 (AP-1) activity 29:76 effects on active oxygen species formation 29:76 effects on azoxymethane induced colon tumors 29:76 effects on cellular differentiation 29:76 effects on cyclooxygenase (COX) enzyme 29:76 effects on cytochrome P450 (CYP) enzyme 29:76 effects on Epstein-Barr virus earlyantigen (EBV-EA) activation 29:76 effects on glutathione formation 29:76 from fungi 29:74 from human peroxidases enzyme 29:76 effects on glutathione-Stransferase induction 29:76 effects on hepatic tumors 29:76 effects on inducible NO synthase enzyme 29:76 effects on mammary DMBADNA adduct 29:76 effects on MU induced mammary tumors 29:76 effects o,, pancreatic tumors 29:76 effects on pulmonary tumors 29:76 effects on TPA-induced EBV activation 29:113 effects on transcription factor (NF-AT) induction 29:76 effects on UVB-induced AP-1 transactivation 29:76 gastric carcinogenesis inhibition by 29:76 in Artemisia sp. 7-208-219 in bioassay systems 29:74 inhibitory effects of 29:113 mono- classes of 29:74 sesqui- classes of 29:74 sester- classes of 29:74 synthesis of 7:87-129;8:33-37 Terpenic indanones 26:701
793
Terpenoid biosynthesis 7:322,330 Terpenoid diketone 9:68,69 from Prosopisjuliflora 9:68,69 Terpenoid intermediates 4:676,677 Terpenoid sapogenins 27:446 Terpenoid 21:272;23:535,548;24:533540;27:20,855 ;29:795 as antiviral compound 24:533540 14ot-hydroxy-7,15isopimaradien- 18-oic-acid as 29:795 Terpenoids (classified) 30:706 diterpenes (C20) 30:706 monoterpenes (C10) 30:706 sesquiterpenes (C15) 30:706 triterpenes and steroid (C30) 30:706 Terphenyllin 29:267 against sea urchin (Hemicentrotus pulcherrimus) embryos 29:268 against Staphylococcus aureus 29:269 analogues as drug 29:270 antioxidant activity of 29:269 as plant growth inihibitor 29:268 biosynthesis of 29:296 cytotoxicity of 29:268,269 3,3 dihydroxy-6'-desmethylterphenyllin as 29:269 dimethylether of 29:268 effects on cell proliferation 29:268 effects on wheat coleoptile growth 29:268 genotoxicity of 29:269 3-hydroxyterphenillin as 29:268 ortho-hydroxy group in 29:269 mutagenicity of 29:269 peroxidation inhibition by 29:269 scavenging effects on a,o~diphenyl-[3-picrylhydrazyl (DPPH) radicals 29:269
o rtho-T erphen ylquino ne phlebiarubrone 29:296 biosynthesis of 29:296
p-Terphenylquinones 29:263 antibacterial activity of 29:264 anti-inflammatory activity of 29:264 anti-insect activity of 29:264 antioxidant activity of 29:264 as atromentin 29:263 as fungal pigments 29:263 as polyporic acid 29:263 as atromentin 29:263 as fungal pigments 29:263 as polyporic acid 29:263 cytotoxic activity of 29:264 from fruiting bodies of basidiomycetes 29:264 numbering systems of 29:264 polyhydroxy-p-terphenyls as 29:264 structure of 29:264 synthesis of 29:299 taxonomical names of 29:264 Terphenyls 29:274 as DPPH radical scavengers 29:274 as PEP inhibitors 29:277 atromentin as 29:271 aurantiacin as 29:272 butlerins A-F as 29:278 curtisian A-D as 29:274 2,3-diacetoxy-4',4",5,6tetrahydroxy-p-terphenyl as 29:274 3,6-dibenzoylatromentin as 29:272 flavomentins A - D as 29:272 from Boletopsis grisea (Polyporus griseus) 29:277 from Lichens 29:278 from Paxillus atrotomentosus vat bambusinus 29:273,274 from Polyozellus multiplex 29:277 from Thelephora ganbajun 29:272,274 functions of 29:271 ganbajunin A as 29:272 ganbajunins C-G as 29:274 in Alzheimer's disease 29:277 isolation by Steglich 29:273
794
leuco-atromentin as 29:273 leucomentins as 29:273 polyporic acid as 29:278 polyozellin as 29:277 thelephorin A as 29:274 thelephoric acid as 29:278 Terphenyls bearing seven oxygenated functions 29:277 against gram-positive bacteria 29:278 cycloleucomelone as 29:278 cytotoxicity data for 29:278 leuco-peracetate as 29:277 polyhydroxy-p-terphenyls as 29:278 protoleucomelone as 29:277,278 4,3",4"-trihydroxy derivative of polyporic acid as 29:277 Terphenyls with alkylated C-18 skeleton 29:291 arenarin B as 29:292 betulinans as 29:291 muscarufin as 29:292 a-Terpincol 25:135,140,141,142, 154 (-)-Terpinen-4-ol 27:370,376 structure of 27:376 Terpinen-4-ol 29:83 activity in AM assay system 29:83 from Melaleuca altemifolia 29:83 ~-Terpinene 21:582,585;29:83 activity in AM assay system 29:83 [3-Terpinene 21:582 T-Terpinene 21:582,585;29:83 activity in AM assay system 29:83 (-)-Terpinene-4-ol 21:585 (+)-Terpinene-4-ol 21:585 (S)-c~-Terpineol 11:288,289 Terpineol 21:595 ot-Terpineol 11:307,308;28:406;29:83 acaricidal property of 28:406 activity in RAS assay system 29:83 preparation of 11:307,308
4-Terpineol 28:426 as bioactive monoterpenoid 28:426 Terpineol-4 20:16 (-)-c~-Terpinol 27:364 (+)-c~-Terpinol 27:364 Terpinolene 29:83 activity in AM assay system 29:83 ~-Terpinyl acetate 21:600 (S)-c~-Terpinyl amine 11:283 alkylation of 11:283 from (-)-ot-pinene 11:288 from (S)-c~-terpineol 11:289 synthesis of 11:288 with indole-protected tryptophyl bromide 11:283 with HN3/BF3 11:288 Terprenins 29:270 against human leukaemia 29:271 against human lung cancer 29:271 against mouse spleen lymphocytes 29:271 antiproliferative activity of 29:271 as antiallergic drugs 29:271 effects on antigen-specific IgE production 29:271 effects on pyrimidine biosynthesis 29:271 synthesis of 29:300 Terramycin 4:609 synthesis of 4:609 Terrecyclic acid 21:233,234 (+)-Terrecyclic acid A 4:674 Terrein 21:239 Terrestrial haloperoxidase 25:758 Terrin 10:152 Terron phoenicoptera 5:837 hemoglobin components of 5:837 Tert-butyl hydroperoxide 25:171 3-Tert-butyl-4-hydroxyanisole (BHA) 25:944,948 Tertiary metabolites 18:680,681 Terulopsis petrophilum 21:758
795
Tessaria dodoneifolia 15:31 ;27:17, 34,35 dihydroquercetin 3-O-acetate 4'methyl ether from 27:17,34 (2R, 3R)-dihydroquercetin 3-0acetate from 27:17,34 Testosterone 25:419,516 3,7,11,15-Tetamethylhexadeca2,6,10,14-tetraene- 1,9-diol 20:25 Tetanus 22:551 Tetaracyclic polyol esters 25:242 Tethysfimbria 19:552 nudibranch from 19:551 O, 'O, O ', O '-Tetraacetyl-4-(4"brombenzyl) vincoside 26:116 O, 'O, O ', O '-Tetraacetyl-4-(4"-brom benzyl) strictosidine 26:127 O, 'O, O ', O '-Tetraacetylsecologanin 26:116,118,125 Tetraacetyltubastrine 5:360 Tetrabenzyl-myo-inositol 18:444 Tetrabutyl ammonium fluoride 11:369 Tetracarbocyclic bridged systems 6:8687 Tetracarbocyclic sesterterpenes 6:58 Tetracarhocyclic fused systems 6:58 Tetrachlorodibenzodioxin 25:767 Tetrachlorodibenzofuran 25:767 2,37,8-Tetrachlorodibenzofuran (T4CDF) 30:763 excretion of 30:763 Tetracyclic diterpenes 6:107;8:220 Tetracyclic intermediates 14:736-738 stereoselective epoxidations 14:736-738 Tetracyclic naphthacene derivative 11:120 from 1,8-dimethoxynaphthalene glutarate 11:120 Tetracyclic polycitrins 23:246 Tetracycline Tetracycline antibiotics 20:520 Tetracycline metabolites 29:315 4-aminoanhydrochlortetracycline as 29:315 anhydrochlortetracycline as 29:315 chloraureovocidin as 29:315 chloro-A-C-diquinone as 29:315
chlorpretetramide as 29:315 chlortetramide-blue as 29:315 chlortetramide-green as 29:315 dehydrochlortetracycline as 29:315 dehydrodemethylchlortetra cycline as 29:315 6-demethyl-6-deoxy-7chloraureovocidin as 29:315 6-demethyl-6-deoxy-7chlortetramide-green as 29:315 methylchlorpretetramide as 29:315 methylchlortetramide-blue as 29:315 methylhydroxychlorpretetramide as 29:315 4-oxoanhydrochlortetracycline as 29:315 4-oxochlortetracycline as 29:315 4-oxodehydrochlortetracycline as 29:315 Tetracyclines 21:109;29:312 anhydrotetracycline 29:312 as halogen acid antibiotics 29:312 chloro derivative of 29:312 demethylchlortetracycline as 29:312 for anthrax 29:312 for bacterial pneumonia 29:312 for brucellosis 29:312 for louse-borne typhus 29:312 for lymphogranuloma 29:312 for pertussis 29:312 for rickettsioses 29:312 for scarlet fever 29:312 for tularemia 29:312 for viral diseases trachoma 29:312 in agriculture 29:312 in calf breeding 29:312 in food additives 29:312 in pig breeding 29:312 in sheep breeding 29:312 metabolites of 29:314 resistance to 29:312 semisynthetic type of 29:312 structure-funtion relationship of
796 29:312 structures of 29:312 synthetic type of 29:312 (+)-(S)-Tetradecan- 13-olide 19:158 isolation of 19:158 Tetradecano- 14-1actone 19:157 isolation of 19:157 12-O-Tetradecanoyl phorbol- 13-acetate 25:44,222,272,542,948 12-O-Tetradecanoylphorbol13-acetate (TPA) 2:286;12:390;21:642,744; 27:482,827,830;30:592,593,695 as tumor-promotion agent 30:592 in vitro bioassays of 30:592 inhibition of 30:695 role in tumor-promotion 30:593 Tetradecanoylphorbolacetate TPA response elements (TREs) 25:524 (2)-5-Tetradecenyl acetate 7:193 (2)-8-Tetradecenyl acetate 7:193 Tetradecyl acetate 7:193 3,4,5,6-Tetradehydro- 18,19dihydrocorynan-thenol 1:124 7,8,7',8'-Tetradehydroastaxanthin 6:153 from Asterias rubens 6:152,161 Tetradehydroastaxanthin 6:153 stereomutation studies of 6:15 (3S, 3S')-7,8,7', 8'-Tetradehydroastaxanthin 6:159 synthesis of 6:157 Tetradehydroastaxanthin diacetate 6:154 Tetradehydroglaucine 3:428 3,4,5,6-Tetradehydrositsirikine 1:124 3,4,5,6-Tetradehydro-[3-yohimbine 1:125,126 2,3,13,15-Tetra-deoxy-evoninol 18:744 2,3,13,15-Tetradeoxy-isoeuoniminol 18:745 Tetradeuteropyrocatechol 8:296 Tetradium glabrifolium 27:164 benzophenanthridine alkaloids in 27:164 Tetradotoxin 21:73 Tetraglycoside 7:268,269,273, 275,281,286 Tetraheptoses 4:196 in Aeromonas hydrophila
chemotype II 4:196 in Vibrio ordalii 4:197 Tetrahydroswertianolin (THS) 25:477 Tetrahydro- [3-carbolines 23:260,266 activity of 23:266 Tetrahydro- 1,2-oxazoles (isoxazolidines) 1:359 reduction of 1:359 Tetrahydro-2H-pyran 11:140,141 from lactol 11:140,141 Tetrahydro-2-oxazinones 12:382-384 acyclic amino alcohol from 12:382-384 1,2(3)-Tetrahydro-3,3'-biplumbagin 2:213,215,216;5:754,755 ~H-NMR spectrum of 2:226,227 UV spectrum of 2:226 structure of 2:226 (S)-Tetrahydro-5-oxo-2-furancarboxylic acid 13:311,325 Tetrahydroalstonerine 13:420,421,423 (+)-Tetrahydroalstonine 13:490,491 synthesis of 13:490,491 (-)-Tetrahydroalstonine 14:563,564 from piperidine 14:563,564 synthesis of 14:563,564 Tetrahydroalstonine 5:127;9:171; 25:30,31 Tetrahydroanabasine 14:739 nitramine from 14:739 via retro Michael reaction 14:748 Tetrahydroanthracenes (vismiones) 7:418-420 antiproliferative activity 7:419 Tetrahydroaplysulphurin-1 9:7,8;17:15 Tetrahydrobellidifolin 25:467 Tetrahydrobenz [c~] anthracene 11:134,135 from triketone 11:134,135 5,6,7,8-Tetrahydrobenze [[3] indolizidine 11:318,319 from allohobartine 11:318,319 Tetrahydrobenzofurofuranol 14:654 preparation of 14:654 Tetrahydroberberine derivatives 6:488,489
797
protopine alkaloids from 6:488,489 Tetrahydrobiopterin 26:917,950 Tetrahydrobisanhydrobacterioruberin 20:599,601 Ag-Tetrahydrocannabinol 19:18; 22:515,537;25:532,533;30:195 as natural analgesic product 30:195 from marijuana 25:532 structure of 30:197 type of classical cannabionoid 30:197 AS-Tetrahydrocannabinol 22:515,537; 30:195 computational molecular modeling of 30:195 QSAR analysis of 30:195 Tetrahydrocannabinol 7:7;30:196 molecular field analysis of 30:196 psychotropic activity of 7:7 A6-Tetrahydrocannabinol (THC) 30:194 as analgesic 30:194 in migraine 30:194 pharmacological properties of 30:195 pharmacological studies of 30:194 Tetrahydrocephalostatin 18:892-895 Fuchs synthesis of 18:892-895 Tetrahydrocorysamine 1:221 ;14:796 corydalic acid methyl ester from 14:796 corynoline from 14:796 synthesis of 1:221;14:796 3,14,4,21-Tetrahydroellipticine 5:125 Tetrahydroeremophilone 15:240 Tetrahydroeucarvone 8:34 Tetrahydroeucarvone trimethylsilyl enol ether 8:34-36 synthesis of 8:34-36 Tetrahydrofuran lignans 26:198,199 Tetrahydrofurans 17:325 Tetrahydrofurofurans 17:344 Tetrahydrogeraniol 21:589 Tetrahydrohalichondramide 17:17 Tetrahydroharmane 5:124
(+) Tetrahydroharmine 25:16 (-)-Tetrahydroharmine 25:18 1,2,3,4-Tetrahydroindolo [2,3-a] quinolizine 1:148 synthesis of 1:148 (+)-Tetrahydroionone 2:163 1,2,3,4-TetrahydroisoquinoIine 22:9 S-Tetrahydroisoquinoline 16:506 Tetrahydroisoquinoline 18:58,595; 25:826,828 Tetrahydroisoquinoline Tetrahydroisoquinoline alkaloids 21:322;23:253 3,14,4,21-Tetrahydroisoquinoline precursors 6:495 cyclodimerization of 6:495 macrocyclic derivatives from 6:495 Tetrahydroisoquinoline systems 6:477 ring destruction of 6:477 1,2,3,4-Tetrahydroisoquinolines 12:446 Tetrahydroisoquinolines 2:172 CD of 2:172 helicity rule for 2:172 Tetrahydrojervine 23:575,585 Tetrahydrokomarovonine 14:762 from Nitraria komarovii 14:762 Tetrahydronaphthalene 11:115 Tetrahydronaphthopyrone 17:361 derivatives of 17:361 Tetrahydronitramarine 14:762 from Nitraria komarovii 14:762 3,14,4,19-Tetrahydroolivacine 5:125 Tetrahydrooxepine 10:588,589 (R)-(+)-Tetrahydropalmatine 10:682,683 synthesis of 10:682,683 Tetrahydropalmatine 21:733;22:22 (+)- 15,20,15',20-Tetrahydropresecamine 5:124 Tetrahydroprotoberberine precursor 6:491 protopine alkaloids from 6:491 S-Tetrahydroprotoberberine-oxidase (STOX) 11:204,205 Tetrahydropyran 10:339 enantioselective synthesis of 1:637
798 from Claisen ester enolate rearrangement 10:339 Tetrahydropyranyl ether 6:264,268 protection with 6:264,268 Tetrahydropyranylation 14:694,695 Tetrahydropyrazinone 10:138-140 preparation of 10:138-140 1,3,4,5-Tetrahydropyrdo [4,3,2,de] quinoline 25:822 Tetrahydropyridine 14:708 alkaline hydrolysis of 14:708 (+_)-3-epi-18,19-dihydroantirhine from 14:708 (+)-3-epi- 18-nor- 18,19dihydroantirhine from 14:708 Tetrahydropyridinium salts 6:447 in coccinelline synthesis 6:447 Tetrahydroschelhammeridine 3:484 Tetrahydrosecodine 19:90 from Rhazya stricta 19:90 16,17,15,20-Tetrahydrosecodine 19:91 1,2,3,4-Tetrahydrosempervirine 1:139 Tetrahydrosquamone 9:398,399 (+)-Tetrahydrostepharine 2:255 Tetrahydroswertianolin (THS) 25:467 hepatoprotective activity of 25:467 Tetrahydroxanthone 25:465 bis-Tetrahydroxanthone 27:849 Tetrahydroxanthyletin 4:396,398 synthesis of 4:396,398 2,3,5,4'-Tetrahydroxy stilbenez-2-O-Dglucoside 27:407,408 5,6,13,14-Tetrahydroxy- 1,2,9,10tetrahydro- 1,9-epoxydibenzo [a,e] cyclooctene 30:227 role in HIV-1 in inhibitor activity 30:227 3fl,6a, 16fl,25-Tetrahydroxy-20(R), 24(S)-epoxy-9,19-cycloalanostane 25:179 3fl,6 a, 16fl,24 a-Tetrahydroxy-20,25epoxy 9/3,19-cyclolanostane 25:184 3fl,6a, 16fl,24 a-Tetrahydroxy-20,25epoxy-9fl, 19-cyclolanostane 25:184
(22R,23R,24S)-2c~,3ot,22,23-Tetra-
h ydro x y-24- methyl- B- homo- 6 a -oxa-5ot-cholestan-6-one 18:495 5,6,7,4'-Tetrahydroxy-3,3',5-5trimethoxyflavone 5:757 2,4,2 ',4 '-Tetrahydroxy- 3 '-prenylchalcone 28:16 aromatase inhibition by 28:16 5,7,2 ',4 '-Tetrahydroxy- 3- geranyl fl avone 28:17 aromatase inhibition by 28:17 3 [3,6cx,12o~,20-Tetrahydroxy-5 cx-cholest9(11)-en-23-one 15:51 313,5,613,15c~-Tetrahydroxy-5c~stigmastan-29-oic acid 15:81 from Myxoderma platiacanthum 15:81 1,3,5,7-Tetrahydroxy-8-isoprenylxanthone 29:571 Candida albicans aspartic protease inhibition by 29:571
1a,7fl,24a,25-Tetrahydroxy-9fl, 19-
cyclolanostane 25:184 Tetrahydroxy-9fl, 19cyclolanost-24E-ene 25:185 Tetrahydroxyethylated rutoside 22:320 (2 S)-5,7,2 ',4 '-Tetr ahydroxyflavanone 28:17 aromatase inhibition by 28:17 7,8,3',4'-Tetrahydroxyflavone 25:541 5,7,3 ',4'-Tetrahydroxyflavone 27:843
(1S,6S,7R,8aR)-Tetrahydroxy-
indolizidine 12:332 1,6,7,8-Tetrahydroxyindolizidine 27:514 Tetrahydroxylated alkaloids 12:349 313,1613,23,28-Tetrahydroxyolean- 12-ene 18:650 3[3,16[3,21 [3,28-Tetrahydroxyoleanan12-en-22-one 27:47,48 structure of 27:48 Tetrahydroxypavinan 30:225 effect on 5-1ipoxygenase inhibition 30:225 Tetrahydroxysterol 23:177 3,3,4,5-Tetrahydroxystilbene 22:626 2',3,4',5-Tetrahydroxystilbene 27:768 3,3',4',5-Tetrahydroxystilbene 27:768
799 2,3.4'-5-Tetrahydroxystilbene-2-O-fl-Dglucoside 22:611,619 1,3,6,7-Tetrahydroxyxanthone 22:662, 664,665 Tetrahydro-fl-carbolines 25:782,815 7,8,11,12-Tetrahydro-~,~-carotene 7:327-329 from t~-carotene 7:327-329 neurosporene from 7:327-329 Tetrahymena pyriformis 2:294;23:71 Tetrahymena thermophilas 2:306; 4:268;23:216 1(2,3,4,6-tetra-O-benzoyl-[3glucop yranosyl)-2-p yri dine from 4:224 1,1,3,3,-Tetraisopropyl disiloxane- 1,3diyl (TIPS) 14:287 desilylation of 14:287 Tetraketides 21:204 Tetrakis (triphenyl phosphine) palladium (0) 10:342;21:746 Tetralins 10:185 [3-Tetralone 9:439 Tetralones 8:401 reduction of 8:402 Tetralysine 25:336 Tetrameles nudiflora 22:533 for convulsions 22:533 Tetramer (russuphelol) 25:765 (24S) 313,5,613,15c~-Tetramethoxy-5(xchole-st-8(9)-en-24-ol 15:76 Tetramethoxyflavone 23:747 3,5,6,7-Tetramethoxyflavone 5:652, 654;7:413 5,6,7,8-Tetramethoxyflavone 5:652;7:413 3,4,3 ',4'-T etrame tho xylignan- 7-o 1 26:228,230 antifungal activity of 26:228 1,1,3,3-Tetramethyl guanidine (TMG) 14:272;19:525 Tetramethyl urea 6:395,396,400 Tetramethylammonium hydroxide 21:51,52 Tetramethylene tetrahydro- [3-carboline N-oxide 14:758,759 biosynthesis of 14:759 from Nitraria komarovii 14:758
Tetramethylene tetrahydro-13-carboline ( 1,2,3,4,6,7,12,12b-octahydroindolo [2,3-a]-quinolizidine) 14:758,759 biosynthesis of 14:759 from Nitraria komarovii 14:758 Tetramethyleneglutaric acid 22:166 Tetramethylethylenediamine TMEDA 5:823 1,1,3,3-Tetramethylguanidine 21:746 2,2,6,6-Tetramethylpiperidine 12:261 N, N,N', N'-Tetramethylsuccinamide 11:115 3,5,8,10-tetraoxododec anedioate from 11:115 Tetramic acid 28:109,110 biological activity of 28:110 13C-NMR of 28:113 derivatives of 28:109 1,5-dihydro-4- hydro xy-2 Hpyrrol-2-one as 28:109 IR values of 28:113 2,4-pyrrolidinedione as 28:109 spectral properties of 28:111 structure of 28:110,111 synthesis of 28:110 UV spectra of 28:113 Tetramic acid antibiotics 14:97-141 biological activity of 14:107-110 synthesis of 14:97-141 Tetramic acid glucosides 25:763 Tetramic acid-4-hydroxy-2-pyridone 21:216 Tetramic acid-containing compounds 28:109
biological activity of 28:109 Tetramorium caespitum 5:235,254 2,5-dimethyl-3-ethyl-p yrazines from 5:223 2,5-dimethyl pyrazines of 5:222 methyl pyrazines from 5:222 Tetramorium impurum 5:235,254 2,5- dimethyl- 3-e thyl-p yrazine s from 5:223 2,5-dimethyl pyrazines from 5:222 methyl pyrazines from 5:222 Tetramycines A,B 6:261 relative configuration of 6:261
800 Tetranactin 16:658 synthesis of 16:658 Tetra-N-butylammonium fluoride 6:119-121 deprotection with 6:119-121 Tetrandine 21:79,80,109 (+)-Tetrandine 29:578 effects on ACE 29:578 (+)-Tetrandine-2'-N-c~-oxide 29:578 effects on ACE 29:578 Tetrandrine 22:20,35;25:472,476 Tetrane isothiocyanates 25:854 Tetraneurin A 29:91 activity in TPA assay system 29:91 (+)-Tetrangomycin 11:136-139 from Streptomyces rimoss 11:135 synthesis of 11:135-139 Tetrangulol 11:135-139 from Streptomyces rimoss 11:135 synthesis of 11:135-139 Tetranichus mites 28:433 neem extracts against 28:433 Tetranichus urticae 28:434 Tetranoic acid 25:695 Tetranortriterpenoids 2:269;9:94,95, 101,297,299 19,19',20,20'-Tetranor-13-carotene 30:550 structure of 30:550 Tetra-N-propylammonium perruthenate 12:312 Tetranychus 28:428 Tetranychus urticae 1:702;28:424,425 2,3,4,6-Tetra- O-acetyl- 1-S-acetyl- 1-thioc~-D-glucopyranose 8:316,318 synthesis of 8:316,318 2,3,4,6-Tetra- O-acetyl- 1-thio-c~-Dmannopyranoside 8:320,321 Tetra-O-acetyl- 1-thio-13-Dgalactopyranose 8:317,339 2,3,4,6-Tetra- O-acetyl- 1-thio- 13-Dglucopyranose 8:323,326 1,2,4,6-Tetra-O-acetyl-2,3-didehydro-3deoxy-ot-D-threo- hexopyranose 14:173
synthesis of 14:173 1,2,4,6-Tetra- O-acetyl-3-deoxy- c~-Dlyxo-hexopyranose 14:173 synthesis of 14:173 1,2,3,4-Tetra- O-acetyl-6-deoxy- 6-iodo[3-D-glucopyranose 8:339 2,3,4,5-Tetra-O-acetyl-D-arabino-hex-2ulosonate 20:859 3,21,22,28-Tetra-O-acetylj egosapogenol 7:141 2,3,4,6-T etr a- O- ac etyl- c~-Dglucopyranosyl bromide 12:382 condensation of 12:382 tjipanazole D with 12:382 2,3,4,6-Tetra- O- acetyl- ~-Dgalactopyranose 21:168,169 2,3,4,6-Tetra-O-acetyl-ot-Dgalactopyranosyl carbamate 21:168 2,3,4,6-Tetra-O-acetyl-c~-Dglucopyranosyl 2,3,4,6-tetra-Oacetyl- 1-thio-c~-D-mannopyranos ide 8:320, 321 2,3,4,6- Tetra- O- ac etyl- cz-D- gluc op yranosyl bromide 8:317,332,338, 363,364 Tetra-O-acetyl-ot-D-glucosyl bromide 14:227 1,3,4,6-Tetra- O-benzyl- 1-thio- [3-Dfructopyranose 8:322 1,3,4,6-Tetra-O-benzyl-Dfructofuranose 8:323-326 synthesis of 8:323-326 Tetra-O-benzyl-D-glucose 10:390 by Wittig reaction 10:390 for synthesis of iodo C-glycosyl derivative 10:390 D- 1,2,5,6-Tetra-O-benzyl-myo-inositol 18:425 D- 1,4,5,6-Tetra-O-benzyl-myo-inositol 18:444 2,3,4,6-Tetra-O-benzyl-~-D-galactopyranosylbromide 14:150 2,3,4,6-Tetra- O-benzyl-a-Dglucopyranosylchloride 8:360,361 thermal glycosidation with 8:360,361 1,2,3,6-Tetra- O-galloyl-13-D-gluco se (galloyl ester) 29:589
801 effects on PEP 29:589 Tetraol 12:237 Tetraol derivative 6:291,292 2,6,8,10-Tetra-O-methyl NDGA 26:191 13,~,6,6'-Tetraoxoalkanedioates 11:114-119 aromatization of 11:114-119 formation of 11:114-119 naphthopyran antibiotics by 11:127-131 Tetraoxoalkanedioates 11:118 BF3 mediated 11:117 from glutaric acid derivative 11:118 from heptanedioic acid derivatives 11:117 from octanedioic acid derivative 11:117 synthesis of 11:117 3,5,8,10-Tetraoxododecanedioate 11:115 from N,N,N',N'-tetramethyl succinamide 11:115 Tetrapanax papyriferum 22:96 N:, N 5, N: o,N: 4_T etra-p-co umaro ylspermidine 29:574 effects on HIV- 1 protease 29:574
N1,NS, N l o,N 14_Tetra_p_coumaro yl_ spermidine synthesis 29:574 from N:,NS, N:~ coumaroylspermidine 29:574 Tetrapeptide derivative 25:376,377 Tetraphyllicine 5:126 Tetraphyllicine dimethoxybenzoate 5:128 Tetraphyllicine monomethoxybenzoate 5:128 Tetraphyllicine trimethoxybenzoate 5:128 Tetraplaura tetraptera 7:434;21:660, 673;22:534 as anticonvulsant 22:534 Tetraponera sp. 6:451 Tetraponerine 1-8 6:451,452 Tetraponerine-7 6:452 Tetraponerine-8 6:452 stereoselective synthesis of 6:452
synthesis of 6:451 X-ray analysis of 6:451 Tetrapyrrole synthesis 9:592-597 enzymes of 9:592-597 Tetrasaccharide globoside 14:150 towards E. coli 14:150 Tetrasaccharides 6:406;7:320, 337;25:295 as transition state analogues 7:337 Tetrastachyne B6 5:124 Tetrasubstituted azulenes 14:343-345 oxidation of 14:343-345 Tetrasubstituted enamino esters 18:358 2,3,4,5-Tetrasubstituted tetrahydrofurans 11:433 synthesis of 11:433 C40Tetraterpenes 7:317 Tetraterpenoids 17:611 1,2,4,5-Tetrathianes 25:842,843 Tetratogenic activity 23:569 ofveratrum alkaloids 23:569 Tetratogenicity 27:309 Tetrazole-catalyzed reaction 14:288 Tetrazoliumblue reagent 19:755 Tetrazomine 10:117,19:289-290 antibacterial activity of 10:117 antitumor activity of
10:117;19:290 antimicrobial activity of 19:290 cytotoxicity of 19:290 isolation of 19:290 structure of 19:289 1,3,4,6-Tetra- O-acetyl- 2- O-trifluoro methylsulfonyl- [3-D-mannopyrano se 8:327 D-Tetritol 6:357 phosphorus analogs of 6:357 Tetrocarcin A 19:118 Tetrocarcin B 19:118 Tetrodotoxin 5:403;7:306;18:697 from levoglucosenone 14:267,276,277 synthesis of 14:267,276,277 Tetrol 5:704-709 ribo-Tetrol 5:705,706,708 L-xylo-Tetrol 5:707,708 synthesis of 5:707,708 Tetrol esters 5:708,709
802
Tetronic acid 6:111;10:261,262,266,272 Teuchamaedrin C 23:618 ~H-NMR data of 23:619 13C-NMR data of 23:619 Teucladiol 23:635 Teuclatriol 23:635 l O-epi-Teuclatriol 23:635 7-epi-Teucrenone B 23:636 ~3C-NMR data of 23:637 Teucrin H-2 23:612 Teucrium alyssifolium 633 Teucrium arduini 30:255 cirsimaritin 4'-glucoside from 30:255
Teucrium botrys 618 Teucrium chamaedrys 23:618 Teucrium divaricatum 23:632 Teucrium flavum 23:621 Teucrium fruticans 7:119;23:630 Teucrium gnaphalodes 23:614,619 Teucrium heteropyllum 23:636 Teucrium japonicum 23:601 Teucrium kotschyanum 23:601 Teucrium lanigerum 23:598 Teucrium massiliense 23:614 Teucrium micropodioides 23:616 Teucrium oliverianum 23:626,623 Teucrtum pestalozzae 23:621 Teucrtum polium 21:584;23:598,633 Teucrium pumillum 23:645 Teucrtum pyrenaicum 23:618 Teucrtum scorodonia 23:598 Teucrium sp. 23:591;26:172;29:687; 30:255 antiseptic agent of 23:642 astringent agent of 23:642 carminative agent of 23:642 diaphoretic agent of 23:642 diuretic agent of 23:642 stimulant agent of 23:642 tonic agent of 23:642 Teucriumlactone 20:74,20:76 Teucrolivin A 23:623 ~3C-NMR data of 23:628 ~H-NMR data of 23:627 NOE experiments of 23:624 Teucrolivin B 23:623 NOE experiments of 23:623,624
Teucrolivin F 23:626-628 13C-NMR data of 23:628 ~H-NMR data of 23:627 Teucvidin 23:594,597,599 ~3C-NMR data of 23:599 ~H-NMR data of 23:599 Teucvin 23:594,597,599 13C-NMR data of 23:599 IH-NMR data of 23:599 Teuflavin 23:622-623 ~3C-NMR data of 23:622 NOE experiments of 23:623 Teuflidin 23:594,597,599 13C-NMR data of 23:599 ~H-NMR data of 23:599 Teuflin 23:596,599 13C-NMR data of 23:599 ~H-NMR data of 23:599 Teugin 23:609 Teugnaphalodin 23:619 ~3C-NMR data of 23:619 ~H-NMR data of 23:619 Teupernin 23:609 Teupernin A 23:609,610 13C-N MR data of 23:610 ~H-NMR data of 23:610 Teupernin B 23:609,610 13C-NMR data of 23:610 ~H-NMR data of 23:610 Teupestalin A 23:622-623 13C-N MR data of 23:622 ~H-NMR data of 23:622 NOE experiments of 23:623 Teupestalin B 23:623 13C-NMR data of 23:622 NOE experiments of 23:623 Teupolin I 23:598 related diterpenoids of 23:600 Teupyrin A 23:618 ~H-NMR data of 23:619 Teurin F 23:609 Teurin G 23:609 Teusalvin A 23:609 Teusalvin B 23:609 Teusalvin F 23:620 12R-epi-Teuscordinin 23:612 Teuvincenone A 23:630 Teuvincenone B 23:630 Teuvincenone C 23:630
803
Teuvmcenone D 23:630 Teuvlncenone E 23:630 Teuvlncenone F 23:630 Teuvlncenone G 23:630 Teuvlncenone H 23:630 Teuvlncenone I 23:630 TG-1 2:445,446 anti-fungal activity of 2:445,446 TG-11 2:446 anti-fungal activity of 2:446 Th2 cells 30:773 differentiation of 30:773 in antibody production 30:773 in humoral immunity 30:773 Th2-type immune response 30:778 inhibition by IFN~, 30:778 Thadiantha grosvenorii 15:22 Thalamocortical connection 30:377 development of 30:377 Thalamus 30:193,377 serotonin synthesis in 30:377 Thalassiosira weissflogii 25:731 Thalassoma bifasciatum 25:787 Thalepogane skeleton 25:688 (+)-Thalicarpine 30:567,595 as platelet aggregation inhibitor 30:594 (+)-Thalicsimidine 16:506 Thalicsimidine 20:301 Thalictricavine 1:220,221;14:771 synthesis of 1:220,221;14:771 Thalictrum 25:180 Thalictrum foliolosum 22:534 Thalictrum isopyroides 22:534 Thalictrum minus vat. Microphyllum 22:534 Thalictrum rugosum 22:534 S-Thalidomide 7:10 from N-phthalyl-L-glutamic acid 7:10 Thalidomide 7:9 from N-phthalyglutamic acid 7:9 synthesis of 7:9 (R)-Thalidomide (hypnotic) 14:517 (S)-Thalidomide (teratogenic) 14:517 Thalifoline 30:566,590 activity in human cancer cell line 30:589 activity in murine cancer cell line
30:589 cytotoxic effect of 30:589 Thaligrisine 22:22 (+)-Thaliporphine 16:509 Thaliporphine 3:426,428 synthesis of 3:426,428 Thallium (III) compounds 20:305,306 Thallium nitrate 4:338 oxidation with 4:338 Thallium nitrate (TTN) oxidation 10:631-635,637,638,640,641,644647,653,654,661,662,666,667 Thallium triacetate 4:72-76 oxidation of 17-hydroxyaspidospermidines 4:74 oxidation of 3-oxo-tabersonine 4:72 oxidation with 4:70-76 Thannilignan 26:224,225 Thapsia sp. 25:536 Thapsia villosa 18:685 Thapsigargin 25:536,543 thebaine 25:533 Thaumatin 15:5,36;27:9,10 analogs of 27:9,10 Thaumatin I 15:5 Thaumatin II 15:5 Thaumatococcus daniellii 15:5;27:19 thaumatin from 27:19 THC metabolites 19:188 detection of 19:188 in human urine 19:188 Thea sinensis 19:247 Theaceae 23:404,405 Theaflavin 20:782;28:274 formation of 28:274 Theaflavin digallate (polycyclic benzopyran) 29:583 effects on type IV collagenase 29:583 Theaflavingallates 28:274 formation of 28:274 Theaflavins 22:187 Thearubigins 28:274 formation of 28:274 Thebaine 18:49,55,57;22:10 neodihydrothebaine from 6:479 [3-Thebainone 18:65 Theileria 26:804
804 Thelenota ananas 7:272;28:593
thelothurin A from 7:273 theothurin B from 7:273 Thelenotoside A 7:273,274 Thelenotoside B 7:273,274,282 Thelephora ganbajun 29:279 Thelephoric acid 29:296 biosynthesis of 29:296 synthesis of 29:298 Thelothurin A 7:273 from Thelenota ananas 7:273 Thelothurin B 7:273 from Thelenota ananas 7:273 Theobroma cacao 21:534;29:606 Theobromine 22:6;25:539 Theoezeolide A 26:1199 Theoneberine 26:1200 Theonegramide 26:1186 Theoneila swinhowe 26:1176-1178, 1180,1186-1191,1194,1196, 1197,1200 Theonella conica 26:1189 Theonella cupola 26:1190 Theonella mirabilis 26:1191;28:716 Theonella sp. 5:355,364;21:393;414; 25:714,715,771,772,775,878,884, 892,900;26:1175,1176,1179,1181, 1184,1188,1193,1198-1200,1212, 1217;28:682;710 aurantoside A and B from 21:414 Theonella sponges 28:681 keramamides F from 28:681 theonellapeptolide congener from 28:681 thiazole-containing cyclic peptides from 28:681 Theonella swinfoei 5:356,396,20:894, 896,589;28:136 Theonelladins A-D 26:1200 Theonellamide 23:341;25:771,772; 26:1185 cytotoxicity of 26:1185 Theonellamides A-F 26:1185 Theonellapeptolides 26:1187-1189 antimicrobial activity of 26:1189 Theonellasterol 26:1176,1177 Theonellasterone 26:1176,1177 Theonellin isothiocynanate 25:848
Theonezolide A 23:221 Theonezolide B 23:223.224 Theonezolide C 23:223 Theonezolides 23:220;28:710 as cytotoxic agents 28:710 ~3C-NMR spectrum of 23:221 ~H-NMR spectrum of 23:221 FABMS spectrum of 23:224 Theonezolides A-C 25:984 Theopalauamide 26:1186 Theopederins 21:393 Theopederins A 26:1199 Theophylline 21:109;22:5,6,27,508; 25:488,539 7-N-Theophylline derivatives 4:225 of galactopyranose 4:225 of glucopyranose 4:225 of glucose 4:225 of mannopyranose 4:225 Therapeutic agents 30:396 for AIDS 30:396 Therapeutic application 30:399 of sulphated polysaccharide (PS) 30:399 Therapeutic effects 27:379 of aroma 27:379 Therapeutic efficacy 21:697 against HSV-1 corneal infection 21:697 of SDB 21:697 Therapeutic potential 27:893 of flavonoids 27:893 Therapeutic uses 22:736 oftropane alkaloids 22:736 Therapeutic vaccines 28:541 against cancer 28:541 Therapy 30:393 for bacterial infection 30:393 for fungal infection 30:393 for parasitic infection 30:393 for viral infection 30:393 Therioaphis maculata 8:221 germacrene-A from 8:221 Thermal [4+2] addition 8:412 Thermal Claisen rearrangement 24:3-5, 29,30 Thermal fragmentation 10:420 of [2'-(phenylselenyl) ethyl] glycoside 10:420
805 Thermal glycosidation (metal free) 8:361,362,365,366 ofallyl glucoside 8:365,366 ofallyl rhamnoside 8:365,366 of (+)-baiyunol 8:362 of cholestanol 8:365,366 of cholesterol 8:361,362,365,366 of decanol 8:362,365 of dihydrolanosterol 8:362,365, 366 of geraniol 8:362,365 of glucoside 8:362,365,366 of glucosyl chloride 8:361,362 of mannosyl chloride 8:361,362 of methanol 8:365 of 1-methylcyclohexanol 8:365, 366 of methyl glucoside 8:365 of rhamnosyl chlorides 8:361, 362 of xylosyl chlorides 8:361 Thermal mannosidation 8:359,369,370 Thermal model ofnociception 30:205 analgesic effect in 30:205 Thermal rhamnosidation 8:359,369,370 Thermally-induced rearrangement 6:468 of ~-hydrastine N-oxide 6:468 of c~-narcotine N-oxide derivative 6:468 Thermitage 25:388 Thermococcus tadyiricus 25:842 Thermodynamic characteristics 27:350 Thermolabile intermediate 21:306 Thermolysis 3:314,315;4:626,627;6:472 of 1,5-benzoxazocine N-oxide 6:472 of 2-benzazocine N-oxide derivative 6:472 of camphor- 10-sulphonyl bromide 4:626,627 of (+)-laudanosine N-oxide 6:472 ofstyryl azides 3:314,315 Thermolytic cyclization 6:429 ofalkenyl azides 6:429 of azides 6:429 Thermophilic bacteria 11:190
Thermophilic bacterium 23:92 Thermoplasma acidophilum 26:1155 Thermopsis chinensis 15:523 (+)-5,6-dehydrolupanine from 15:523 Thermopsis lupinoides 15:523 (+)-lupanine N-oxide from 15:523 Thermospray Ionization Mass Spectrometery (TSP-MS) 19:750 Theronine deaminase 25:370 Thespesia populnea 27:855 Thevisidol 7:467 Thexyl borane 4:116,117 hydroboration with 11:83 reduction with 4:116,117 Thiaarachidonic acids 9:569,570 Thiarubrine A&C 26:437 Thiazinotrienomycin 23:54 Thiazinotrienomycin A 23:77,97 Thiazinotrienomycin B 23:97 Thiazole alkaloid 25:711 Thiazole amino acids 4:83-86 Hantzsch synthesis 4:85,86 synthesis of 4:83-86 via thiazolidine 4:85 Thiazole nucleoside 10:392 by Wittig condensation of 10:392 from ribofuranose 10:392 Thiazolidenedione class 21:488 Thiazolidine 14:735 chiral auxiliaries from 14:735 into tin(II) enolates 14:735 transformation of 14:735 Thiazoline 25:881 3-Thiazoline derivatives 12:129 Thiazolo [4,3-a] isoquinoline 12:447 E-2-Thiazolyl-c~, [3-enones 30:443 2-Thiazolyl methylenetriphenyl phosphorate (2-TMP) 11:443,444 2-Thiazolylcarbonitrile N-oxide (2TNO) 11:443,444 Thief ants 6:434 trans-2,5-dialkylpyrrolidines in 6:434 2,5-dialkylpyrrolines in 6:443 (5Z,8E)-3-heptyl-5-methyl pyrrolizidine in 6:445
806
Thiele acetylation 10:120,121 (+)-Thienamycin 13:498-504 synthesis of 13:498-504 Thienamycin 4:431,432;12:145 absolute stereochemistry of 4:433,435,440,464 antibacterial activity of 4:431,432;12:145 antibiotic activity of 12:122 biosynthesis of 4:434; 11:210,211 by Sharpless method 4:438 carbapenem antibiotic 11:210 chemical shifts of 4:442 from 3-hydroxybutyric acid 4:438 from glutamic acid 11:210,211 from methionine 11:210,211 from Streptomyces cattleya 12:145 immipenem derivative of 4:431,432 Kuhn-Roth oxidation of 11:210,211 PBP-2 affinity for 4:433 structure elucidation of 12:145 structure of 4:433 ~-lactamase inhibition by 12:145 [3-1actamase stability of 4:431 nor-Thienamycine 4:434 4H-Thieno [2,3-D] azonine derivative 6:476 synthesis of 6:476 Thieno analogues 6:491 of protopine alkaloids 6:491 synthesis of 6:491,492 X-ray analysis of 6:491 Thienopyridines 1:167 (2E)-5-(2-Thienyl)-2-penten-4-ynal 10:153 (2-Thienyl)-acetic acid 6:322 synthesis of 6:322 from 2-thiphene carbaldehyde 6:322 Thin layer chromatography 2:368;9:164 for culture development 2:368 of indole alkaloids 9:164 Thio sugars 6:351-384
19,10-Thio-3-epi-gibberellin A ~ 8:125,126 synthesis of 8:125,126 Thioacetal 14:660,661 hydrolysis of 14:660,661 with cadmium carbonate 14:660 with mercury (II) chloride 14:660 Thioacetates 28:666 absolute configuration of 28:666 conversion to furodysin 28:666 Thioacrolein 23:464 Thioaldehyde cycloaddition 8:207-217 Thioaldehyde Diels-Alder reaction 8:207,210,213 6-Thioallolactitol 8:353 6-Thioallolactose 8:338,339 Thioallolactose 8:339,342,353 Thio-analogues 7:48 of galactosides 7:48 Thiocarbafuranoses 29:465 arabinocarbafuranose as 29:466 lyxocarbafuranose as 29:466 TB SOTf/DIPEA-promoted silylative protocol for 29:465 Thiocarbapyranoses 29:488 as neuraminidase inhibitor 29:488 contracted type of 29:490 expanded type of 29:490 in medicinal chemistry 29:488 Thiocarbapyranose synthesis 29:488 by Lew and Kim 29:488 by Rassu 29:489 a-Thiocarbocation 1:240 Thiocarbonate 1:442,443 pyrolytic elimination of 1:442, 443 Thiocarbonylimidazole 19:54 4-Thiocellobiose 8:332,333,351,352 4-Thiocellooligosaccharides 8:348,349 Thio-Claisen rearrangement 1:53; 14:865-867 isovelbanamine by 14:865-867 velbanamine by 14:865-867 Thiocoraline 25:842 Thiocyanate 8:316;21:346 Thiocyanate-derived functionally 21:329
807
(IS*,4S*, 6S*,7R*)-4-Thioc yanato- 9cadinene 28:660 X-ray analysis of 28:660 2-Thiocyanatoneopupukeanane 25:859 (-)-4-Thiocyanatonepupukeanane 25:858 2-Thiocyanatopupukeanane 21:346 (1R*,2R*,5R*,6S*,7S*)-2-Thiocyanatopupukeanane 25:869 Thiocyanotoneopupukeanane 25:858 Thiodepsipeptide thiocoraline 25:841 5-Thio-D-glucose 6:351 4-Thiodisaccharide 8:330,332 Thiodisaccharides (1-->4) linkage 8:329 1,2-trans 1-Thiodisaccharides 8:317, 318 1-Thiodisaccharides 8:317-326 synthesis of 8:317-326 Thiodisaccharides 8:317-340 synthesis of 8:317-340 Thiodisaccharides (1-->2) linkage 8:327 Thiodisaccharides (1-->3) linkage 8:329 Thiodisaccharides (1-->6) linkage 8:338 Thiodisaccharides (6-->6) linkage 8:340 5-Thio-D-mannopyranose 6:351 5-Thio-D-mannose 28:715 as naturally occurring 5-thiosugar 28:715 Thioesters 4:554 acylation of phosphonium ylides 4:554 3'-Thioether 27:331 Thiofurodysinin 25:814;28:667 as furanosesquiterpene 28:667 Thiofurodysinin acetate 25:814,815 6-Thiogentiobiose 8:337,338 7-Thiogibberellin 8:123,124 synthesis of 8:123,124 19,10-Thiogibberellins 8:124,125 synthesis of 8:124,125 3-Thioglucofuranose-(3--> 1)-[3-xylosyl3-thioglucofuranosethiodisaccharides 8:329 1-Thioglycerol 2:20 in FAB mass spectrometry 2:20 1-Thioglycoses 8:316,323, 326,328,329,332
Thioglycosides 1:429,430 synthesis of 1:429,430 1-Thioglycosides 1:429,430;8:315-317; 8:315-317 synthesis of 1:429,430 Thioglycosidic linkage 16:114 4-Thioglycosyl maltotriosides 8:343,344 2-Thio-hexopyranose-4-ulo se nucleosides 4:252 synthesis of 4:252 Thiohydroximate- O-sulphonate 26:480 1-Thioisosucrose (~-D- fructo- furano syl 1-thio- ~-D-glucopyranoside) 8:324 synthesis of 8:326 Thioketalization 14:680,681 ;24:80 2-Thiolacetate 8:322 Thiolacetates 8:317 ),-Thiolactone 8:125,126 Thiolactone 8:206,207 synthesis of 8:206,207 4-Thiolactose 8:334,335 Thiolbenzoates 8:316 Thiolester 12:147 with triethyl phosphite 12:147 Thiolester enolates 12:167-170 4-acetoxy-[3-1actam with 12:167170 C4-alkylation with 12:167-170 Thiolesters 8:316 5-Thio-L-rhamnose 6:351 4-Thiomaltose 8:331,332 4-Thiomaltoside 8:330,331 synthesis of 8:330,331 4-Thiomaltotriose 8:343,344 4'-Thiomaltotrioside derivative 8:343,345 synthesis of 8:343,345 Thiomarinol A 25:840 Thiomarinol C 25:840 Thiomarinol D 25:840 Thiomarinol F 25:840 Thiomarinol G 25:840 Thiomarinols 25:838,840 Thiomercury derivatives 8:316 cc-Thiomethylpyrrole 9:593 3-Thiomethylrifamycin S 23:61 3-Thiomethylrifamycin SV 23:55
808
Thiomycalalides A and B 25:831 Thionins 22:75 Thionolactones 10:208 by macrolactonization 10:208 desulphurization of 10:208 synthesis of 10:208 Thio-oligonucleotide 13:283 Thio-oligosaccharides 8:316-346 reaction with enzymes 8:315 synthesis of 8:316-346 Thiophanate-methyl 22:462 Thiophene 7:202,203,222 Thiophene C-glycosides 10:349 from glycals 10:349 Thiophene derivatives 7:222 2-Thiophenecarbaladehyde 6:322 (2-thienyl)-acetic acid from 6:322 Thiophenes 24:521,522 as antiviral compound 24:521, 522 Thiophenol 6:542;14:750 elimination of 6:540 Thiophenolate complex 14:750 non-chelating 14:750 Thiophenyl-glycosides 10:381 allylation of 3:222 Thiophosgene 22:288 Thiophosphoramidites 13:269,270 phosphorodithioates from 13:269,270 2-Thiosophorose 8:326,327 synthesis of 8:326,327 Thiostrepton 11:209,210 biosynthesis of 11:209,210 from quinaldic acid 11:209,210 from Streptomyces azureus 11:209 1-Thiosucrose 8:323,325,326,348 synthesis of 8:323,325,326,348 Thiosugars 8:315 5-Thiothistidine derivative 25:813 2-Thiothistidines 25:813 4'-Thio-toyokamycin 6:351 Thiotrisaccharides 8:340,341 cis-2 -Thioxocyclopenta[d]pyrimidine4-one 22:291 2-Thioxopyrrolidines 26:1098 antifungal activity of 26:1098
3-Thioxovincadifformine 19:103 2-Thioxylobiose 8:328 synthesis of 8:328 3-Thioxylobiose 8:329 4-Thioxylobiose 8:336 4-Thioxylobioside 8:349 4-Thioxylooligosaccharides 8:348,349 1-Thioxylose 8:336 1-Thio-a,c~-dimannosyl analog of c~,~trehalose 8:321 1-Thio-c~,ct-disaccharide 8:319,320 1-Thio-a,ct-trehalose 8:318322,347,348 1-Thio-a,13-disaccharide 8:318,319 1-Thio-ct-D-glucopyranose 8:318,340 1-Thio-[3,[3-trehalose 8:317,347 1-Thio- [3-D-galac top yrano se tetraacetate 8:317 1-Thio-D-D-galactopyranoside 8:315 1-Thio- 13-D-gluc op yrano se 8:332,333,340 1-Thio-~-galactopyranosides 7:48 inhibition constants of 7:48 Thitsiol 9:319,340,336,360 Thladiantha grosvenorii 15:5 Thomasic acid 17:338 synthesis of 17:338 Thopsentia sp. 26:464,466 Thorecta choanoides 15:312;25:694 Thorecta sp. 5:410 Thorectandra excavatus 18:717 Thorectolide monoacetate 18:717 Thorectopsamma xana 25:844 Thornasteroside A 7:286290,293,299; 15:45,52 from Acanthaster planci 7:288 from Asterias annurensis versicolor 7:287 from Linckia laevigata 7:290 fromLuidia maculata 7:289 from Nordoa gomophia 7:290 from Thromidia catalai 15:46 retro-aldol reaction of 7:291 24R-and (24S)-Thoronasterol A 15:48 Thorpe-Ziegler reaction 10:328 Three component reaction 4:572,573 Three dimensional NMR spectroscopy 26:1044-1046
809
Three-carbon almulations 6:42,49,50, 52,74,75 in (+_)-A9(12) capnellene synthesis 6:42 in capnellenol synthesis 6:48,50 in dolasta-1 (15), 7,9-trien-14-ol synthesis 6:52 Three-carbon ring expansion 10:330, 331 (-)-muscone by 10:330,331 Three-dimensional structure 20:903-907 of microcystins 20:903-907 of nodularins 20:903-907 (+)-Threitol 4:325,326 ketalisation with 4:325,326 resolution ofketones with 4:325,326 synthesis of 4:324,325 D-Threitol 6:355 phosphorus analogs of 6:355 L-Threitol derivative 11:238,239,246249 L-Threitol tetraacetate 4:505 synthesis of 4:505 Threo ethyl [3-hydroxy-[3-(2-piperidyl) propanooates 12:279 from ethyl [3-hydroxy-13-(2pyridyl) propanooates 12:279 Threo-2-amino alcohols 12:430,431 interconversion of 12:430,431 stereoselective synthesis of 12:489-493 to erythro-2-amino alcohol 12:430,431 Threo-configurational product 12:415,416 Threo-erythro interconversion 12:430, 431 of 2-amino alcohol 12:430,431 L-allo-Threonin 4:134 in methyl-L-sibirosaminide synthesis 4:135 D-Threonin 4:134-136 in lincosamine synthesis 4:140,141 A-2-oxazoline from 4:140,141
D-allo-Threonin 4:134-136 in D-glycero-D-mannoheptose synthesis 4:205 D-Threoninal 4:135,136 D-allo-Threoninal 4:135,137,143-145 N,N-diprotected 4:145 in heterodienophile 4:143 Threonine 22:21 ;27:850 activity of 27:850 L-Threonine 4:134,149;16:4,7-9 Threonine kinases 27:824 D-Threose 3:185 synthesis of 3:185 Threo-selective reduction 12:300 Threo-c~-methyl-[3-bornyl carboxylic ester 11:425 from (c~-bromoalkyl) boronic ester 11:425 Threo-[3-hydroxyglutamic acid 12:430,431 mutual transformation of 12:430,431 with erythro derivative 12:430,431 L- Threo-f3-methylaspartic acid 14:102 Throboxane A2 25:600 Thrombin 30:70,594,838 platelet aggregation induction 30:by 594 role in blood coagulation 30:70 role in platelet activation 30:70 role in pulmonary vascular injury 30:70 Thrombin fibrin clots 30:154 generation of 30:154 Thrombin receptor agonist peptide 30:69,70 in cultured HUVECs 30:69 Thrombin time assay 30:403 Thrombin-induced adhesion 30:55 Thrombin-stimulated ELAM- 1 30:70,71 inhibitory effect on 70,71 Thrombocystosis 30:839 treatment of 30:839 Thrombolytic agent 30:839 adverse effect of 30:839 bleeding complications due to
810 30:839 recombinant prourokinase (proUK) as 30:839 recombinant tissue-type plasminogen activator as 30:839 re-occlusion due to 30:839 staphylokinase as 30:839 Thromboplastin time assay 30:403 Thrombosis 30:55,839,840 role of natural products in 30:55 treatment of 30:839,840 Thromboxane 5:513 ;22:25,616,629 semi-synthesis of 17:642 synthesis from glucose 3:226,227 Thromboxane A2 26:266 Thromboxane B2 10:419;22:112 synthesis of 10:419 Thromboxane synthase inhibitor 25:593 Thromidia catalai 7:299;15:46 thornasteroside A from 15:45 Thromidioside 7:299,302 Thromolysin 25:438,439 Thrush 2:422 tomatine 2:46 DCI spectrum of 2:46 THS hepatocyte apoptosis effect 25:467 THS inhibited hepatocyte apoptosis 25:468 Thuidiaceae 29:321 Thuja occidentalis 2:402,20:16 Thuja orientalis L. 20:16;22:534 for convulsive disorders of children 22:534 Thuja plicata D. 5:476;14:389,390; 16:269;17:338;23:343 ;26:188; 27:384;28:408 thujone from 14:389,390 Thuja standishii 29:87,101 cis-[3-Thujaketonic acid 14:392,393 a-Thujaketonic acid 14:392,393 from thujone 14:392,393 trans-f3-Thujaketonic methyl ester 14:393,395 [3-Thujaplicin 1:572 synthesis of 1:572
a-Thuj aplicin 29:583 effects on carboxypeptidase A 29:583 Thujia orientalis 8:3 essential oil from 8:3 Thujic acid 22:393 Thuj one 14:390-447;20:16 from cedar leaf oil 14:389 from Thuja plicata 14:389 insect juvernile hormone analogues from 14:391-397 (+)-3-Thujone 27:384 [3-Thujone 28:427 acaricidal activity of 28:427 a, [3-Thujone 9:530 Thujopsis 26:172 Thujopsis dorablata 21:621;29:583 Thujopsis plicata 29:583 Thujopsis sp. 21:615 Thuya occidentalis 21:617 Thymbra spicata 30:272 luteolin from 30:272 Thymelaceae 25:242,243,246 Thymelaceous plants 27:833 activator from 27:833 Thymic humoral factor-gamma 2 27:804 Thymidine 23:97 3H-Thymidinemethod 25:266 Thymidylate 22:29 Thymine polyoxin C 1:404,405 Thymine-guanine 22:28 Thymocytes 9:390 Thymol 13:299,300;21:596,598, 599,601,602,613;28:426 as bioactive monoterpenoid 28:426 Thymoquinones 5:774 al-a~-Thymosin 8:433 Thymosin at 8:1,433,434 by recombinant DNA cloning 8:437 by solid-phase 8:437-439 by solution 8:439-446 synthesis of 8:437-446 Thymosin a~ 8:433,434 synthesis of 8:447 Thymosin [3II 8:435
811
Thymosin ~12 8:435 Thymosin ~4 8:448
by recombinant DNA cloning 8:448 by solid phase 8:448,449 by solution method 8:449-453 synthesis of 8:447-453 Thymosin 134xen 8:435 Thymosin ~4 Ala 8 : 4 3 5 Thymosin [39 8:453-455 by solid phase method 8:453-455 by solution method 8:453-455 synthesis of 8:453-458 c~-Thymosins 8:433;27:804,806 ~-Thymosins 8:433,436;27:804 y-Thymosins 8:433 Thymosins 8:433,437-458 synthesis of 8:433,437-458 Thymovar 28:391 employed as Frakno thymol frame 28:391 Thymus peptides 8:433 Thymus piperella 30:263 luteolin 7-glucoside from 30:263 Thymus sp. 21:598;26:172,746;29:579 Thymus vulgaris L. 21:599,617,619, 621 ;27:374 ;28:390;391,415 Thyroid hormone 27:314 Thyroxine 27:314 Thyrsiferol 5:361-363 biogenesis of 5:363 Thyrsiferyl-23-acetate 5:361-363 Tiam et al. 29:198 carnosic acid synthesis by 29:198 Tibouchina semidecandra 23:404,405 Tigliane 12:246 Tigliane diterpenoids 25:542 Tigliane diterpenoid esters 25:543 4-deoxyphorbol 25:543 12-deoxyphorbol 25:543 4,20-dideoxy-5-hydroxyphorbol 25:543 Tigliane ring system 12:245-265 construction of 12:245-265 Tigliane skeleton 25:242 Tiglic acid 5:778 HETCOR spectrum of 5:778
Tigloylgomisin P 26:197 6c~-Tigloyloxy chaparrin 7:381,382 c~-Tigloyloxy chaparrinone 11:4,6 (-)- 13c~-Tigloyloxymultiflorine 15:524 fromLupinus hirsutus 15:524 3fl-Tigloyloxytropane 22:729 3-Tigloyltropine 21:56 [3-Tigogenin cellobioside 21:671 Tilapia mossambica 5:370 Tilapia nilotica 7:183,185,187 Tilia chordata 22:679 Tilia sp. 21:537 Tiliaceae 23:511,533 Tilletiopsis sp. 5:291 Time-off-flight (TOF) mass spectrometer 25:434 Time-resolved resonance Raman spectroscopy 30:540 Timosaponin 24:919-922 anti-hyperglycemic effects of 24:919-922 chemical structure of 24:921 potentiation of pilocarpineinduced saliva secretion by 24:921 Tin (II) enolate 12:164 of achiral thiazolidin-2-thione derivative 12:166 with tin triflate 12:164 Tin acetylide 1:475 palladium mediated acylation 1:475 Tin enolate 12:170 from ketone 12:170 with 4-acetoxy-[3-1actam 12:170 with high [3-selectivity 12:170 Tin hydride reduction 12:271 Tin c~-alkoxyanions 3:281 Z-trisubstituted olefins from 3:281 Tin(II) enolates 14:735 thiazolidines from 14:735 Tin-assisted tosylation reaction 30:463 Tinea pedis 474 Tingenol 18:778 Tingenone 5:744,746,747,750;7:145, 146,149;18:757,760,776;23:709;26:8 13,814;30:665,668
812 structure of 30:665 Tiotropium 22:738 Tiphia sp. 5:225,253 Tiqueside 21:671 Tirandalydigin 14:97,104 from Streptomyces tirandis 14:98 Tirandamycic acid 10:423 from pyranosidic glycal 10:423 synthesis of 14:103 (+)-Tirandamycic acid 16:661 synthesis of 14:110-112,127-129 Tirandamycin 3:268 (+)-Tirandamycin A 14:120-123,129132,134-138 total synthesis of 14:120123,129-132,14:134-138 Tirandamycin A 14:97,100,101,103,115 biological activity of 28:131 from Streptomyces tirandis 14:98 total synthesis of 14:115 (-)-Tirandamycin A 16:661 total synthesis of 14:114-
117,129-132
(+)-Tirandamycin B 14:123-126 total synthesis of 14:123-126 Tirandamycin B 14:97,98 from Streptomyces flaveolus 14:97,98 Tirotundin 29:89 activity in NFkB assay system 29:89 Tirucalla-7,24-dien 1613-ol 9:301 Tirucalla-8,24-diene- 16-one 9:302 Tirucallanes 9:297,300, 302,307;25:50 Tirucallin B 23:406 DT-Tirucallol 9:301 AT-Tirucallol (tirucalla-7,24-dien-313-ol) 29:588 effects on CHY 29:588 Tissue bioassays 29:29 Drosophila melanogaster use in 29:31 ecdysone activity in 29:31 20-hydroxyecdysone activity in 29:31
imaginal disc bioassay as 29:29 inokosterone activity in 29:31 makisterone A activity in 29:31 ponasterone A activity in 29:31 rubrosterone tested in 29:31 use of Calliphora victina in 29:31 use of Chilo suppressalis in 29:29 Tissue culture 7:146,371,376,389;23:12 of Maytenus buchanii 7:146 of Tripterygium wilfordii 7:146 Tissue plasminogen activator (t-PA) 30:830,844 Tistularin 25:720 Titanium 4:421-535 reductive elimination with 4:421-535 Titanium (IV) catalyzed 12:241 cyclization 12:241 Titanium (O) 11:366,367 by titanium trichloride 11:366,367 preparation of 11:366,367 with potassium graphite 11:366,367 Titanium reagent 3:80,81 ;11:366,367 application of 11:371 discovery of 11:366,367 in dicarbonyl coupling 3:80,81 Titanium tetrachloride 11:358 Titanium tetrachloride catalyzed reaction 8:141-143,146,151 of acrylate 8:142 Titanium tetrachloride method 4:252 for 6-deoxynucleoside synthesis 4:232 Titanium tetraisopropoxide 4:505 in stereoselective epoxidation 4:505 Titanium trichloride 11:366,367 titanium (O) from 11:366,367 with potassium graphite 11:366,367 Titanium-induced carbonyl coupling reactions 8:15,25,31 Titanium-induced coupling 11:345,368 Titanium-induced intramolecular pinacol coupling 8:18
813
Titanocene dichloride 10:30 Tithofolinolide 29:87 activity in DIF assay system 29:87 Tithonia diversifolia 29:90 Tjipanalzole A1 12:371 from Tolypothrix tjipanasensls 12:366 Tjipanazole A2 12:366,371 from Tolypothrix tj'ipanasensls 12:366,371 Tjipanazole B 12:366,371 from Tolypothrix tjipanasensls 12:366,371 Tjipanazole C1 12:366,371 from Tolypothrix tjlpanasensts 12:366,371 Tjipanazole C2 12:366,371 from Tolypothrix tjipanasensts 12:366,371 Tjipanazole C3 12:366,371 from Tolypothrix tjipanasensls 12:366,371 Tjipanazole C4 12:366,371 from Tolypothrix tjipanasensts 12:366,371 Tjipanazole D 12:382 condensation of 12:382 from Tolypothrix tjipanasensis 12:366,371 synthesis of 12:282 tjipanazole E from 12:382 with 2,3,4-tetra-O-acetyl-a-Dglucopyranosylbromide 12:382 Tjipanazole E 12:382 from Tjipanazole D 12:382 from Tolypothrix tjipanasensis 12:366,371 synthesis of 12:382 Tjipanazole F~ 12:366,371 from Tolypothrix tjipanasensis 12:366,371 Tjipanazole F2 12:366,371 from Tolypothrix tjipanasensis 12:366,371 Tjipanazole GI 12:366,371 from Tolypothrix tjipanasensis 12:366,371
Tjipanazole G2 12:366,371 from Tolypothrix tjipanasensis 12:366,371 Tjipanazole I 12:366,371 from Tolypothrix tjipanasensis 12:366,371 Tjipanazole J 12:366,371 from Tolypothrix tjipanasensis 12:366,371 TLR2 30:777,778,781,782 from gram-positive bacteria 30:778 in ARS-2 mediated cellular activation 30:781 in cellular reponses 30:782 T-Lymphocytes 22:259;27:799 TMAO-urea complex 18:678 TMB (3,4,5,-trimethoxybenzoy) 25:477 cytotoxic action of 25:477 TMG 21:746 2-TMP (2-thiazolyl methylene triphenyl phosphorate) 11:443,444 TMS enol ether 4:8,10,36,38 formmation from ketone 4:8,10 TMS triflate 1:514 TMSI 21:740,746 TMSOF (2-(trimethylsiloxy) furan) 11:451,453 TMSOTF 1:308;4:91,92 deblocking of BOC 4:91,92 TNF-c~ 21:616;25:461,462-465,469, 472,474;28:320 caspase activity of 28:320 dependent liver injury 25:470 in macrophages treatment 25:473 oncolytic effects 25:460 inhibition by THS 25:468 TNF-c~ bioassay system 29:103 acanthoic acid activity in 29:103 2c~-acetoxy- 14-hydroxy- 15-isovaleroyloxy-9-oxo-costunolide activity in 29:89 TNF-c~ cytotoxicity 25:475,477 TNF-c~ dependent liver injury 25:472, 473,476,477 TI~F-c~ induced lethality 25:474
814 TNF-ot production 25:468,470,471473,475 suppression of 25:472 inhibition of 25:475 TNF-c~ receptor (TNF-R) 25:477 TNF-c~ release 28:220 Artocarpus flavonoids against 28:220 TNF-c~-dependent inflammatory liver injury 25:460,461,465,466 TNF-c~-dependent models 25:476 TNF-c~-gene expression 25:470 TNF-ot-induced hepatocyte apoptosis 25:471 TNF-Gt-induced hepatotoxicity 25:469,471 TNF-c~-mediated cytotoxicity 25:466 TNF-ct-sensitive L929 cells 25:467 2-TNO (2-thiazolylcarbonitrile N-oxide) 11:443,444 Tobacco budworm 12:397 Tobacco hornworm 24:865 bioassay of 24:865 Tobacco mosaic virus infection 30:412 against yeast mannans 30:412 Tobacco norsesquiterpenes 3:58 Tobacco protoplasts 25:380 Tobacco syntaxin 27:330 Tobagolide 23:172 acetylation reaction of 23:172 Tobramycin 14:145 (+)-~-Tocopherol 26:251,258,261 (+)-y-Tocopherol 26:261 ot-Tocopherol 9:313,579,580;22:318, 326,358 ;23:771 ;25:236,792,930,936, 944,946;26:337,993,1006 phosphatidylcholine 22:318 synthesis of 4:494-501 synthesis of chroman ring 1:644, 645 synthesis of side chain 1:644,646 c~-Tocopherolquinones 30:304 as primary metabolites 30:304 Tocopherols 27:700 from olive oil 27:700 TOCSY 2D 6:140 TOCSY-1D 6:140 Toddalia 27:164
Toddalia aculeata. 27:158,164,177 Todolactol A 20:619 Todolactol B 20:614,616,617,619 Todolactol C 20:616,619 Todolactol D 20:618,619 Todomatsu 20:613 Todomatuic acid 22:385,391 Toga virus infection 30:409 in pregnant women 30:409 vaccination against 30:409 Toga viruses 30:394,409 (R)-Tolbinap-ruthenium (II) complex 12:153 (S)-Tolbinap-ruthenium (II) complex 12:153 Tolerance 30:194,799 due to analgesic alkaloid 30:799 due to opioids 30:194 Tollens oxidation 8:25 with AgNO3 8:25 Tolrestatin 22:171 Toluamide 21:735 (rt-Toluenesulfonyl) methyl isocyanide (TOSMIC) 3:321,322 double addition of 3:321,322 (p-Toluenesulfonyl) methyl isocyanide(TOSMIC) 3:321,322 double addition of 3:321,322 para-Tolyl isocyanate 21:169 2-(p-Tolyl)-sparteine 27:263 monoperchlorate salt 27:263 Tolypathrix nodosa 25:691 Tolypocladium geodes 21:225 peptaibols from 21:225 Tolypocladium inflatum 21:225;22:257 Tolypocladium niveum 21:225,227 Tolypocladium niveus 26:486 Tolypodiol 29:100 activity in TPA assay system 29:100 Tolypomycin 23:54 Tolypomycinone 23:56 Tolypothrix nodosa 21:275;29:100 TOMAC 6:326,330 Tomatidine 7:19,21 ;21:84;23:573, 576,584 ;25:295,296,297,300,301, 306,316-318 detoxification of 25:293 enzymatic detoxification of
815
25:304 mechanism of action of 25:306 Tomatidine-3 ~-lycotetrose 23:585 fl2-Tomatinase 25:306 Tomatinases 25:306 Tomatine 7:18,19,21 ;21:79,80;25:294, 295,296,297,298,299,300,301,302, 306,311,312,315-322;26:818 glycoalkaloid 25:304 deglycosylation 25:295 c~-Tomatine 25:293,296,297,306;26:467 steroidal glycoalkaloid 25:294 fll-Tomatine 25:295,314,317 fl2-Tomatine 25:295,301,306,317 7-Tomatine 25:296,297 6-Tomatine 25:296 Tomatine subproducts 25:317 Tomatine-detoxyfying enzymes 25:293 Tomato (pro) systemin 25:371 Tomato chalcones 23:744 Tomentosic acid 23:515 Tomentoside 25:199 Tomentoside II 25:199 Tonic 30:64 carp as 30:64 Tonic agent 23:642 of Teucrium sp.as 23:642 Tonsillitis 30:88 use of Platycodon grandiflorum in 30:88 Toothache 30:203 use of ginseng root in 30:203 TOP-53 26:163 in anticancer treatment 26:163 Topa 23:241 Topa quinone 26:1259,1266-1269,1284, 1285 Topoisomerase 21:634;23:537 Topoisomerase (TOPO) II-mediated decateration of kinetoplast DNA 25:820 Topoisomerase 1-inhibitory properties 27:851 from Tabebuia avellanadae tree 27:851 Topoisomerase I 16:27;25:721 Topoisomerase I and II 12:370,394, 396,20:500
Topoisomerase I inhibition 26:825 Topoisomerase II 5:581,16:27,20:246; 21:269;25:708,709,862 Topoisomerase II activity 23:245 Topoisomerase II expression 26:924 Topoisomerase II-sensitive (CHO) cell line Xrs-6 25:824 Topoisomerase inhibitory 24:867,868 bioassay of 24:867-868 Topoisomerase inhibitory activity 24:848 of costunolide 24:848 Topotecan 13:655,20:458;21:136 Topozolin 28:229 biological activity of 28:229 Topsentia sp. 25:704;28:701 in guanosine diphosphate/Gprotein RAS exchange assay 28:701 sulfates of 28:701 topsentiasterol sulfate A from 28:701 topsentiasterol sulfate B from 28:701 topsentiasterol sulfate C from 28:701 topsentiasterol sulfate D from 28:701 topsentiasterol sulfate E from 28:701 Topsentia sponge 27:861 Topsentinols A-J 25:703 Torachroysone-8-O-D-glucoside 22:609 Tormentic acid (triterpene) 22:125; 29:575;30:207 antinocicieptive effect of 30:207 effects on HIV- 1 protease 29:575 Torpane alkaloid 25:530 atropine 25:530 cocaine 25:537 ecgonine 25:537 hyoscamine 25:530 hyoscine (scopolainine) 25:530 Torpedo califronica 18:721 Torrentin 7:233 Torresea acreana 29:599 Torularhodin 7:339 from Rhodotorula rubra 7:340
816
Torulopsis colliculosa 5:283,292 Torulopsis glabrata 25:258 Torulopsis gropengiesseri 5:293 Torulopsis lactis-condensi 5:293 Torulopsis magnoliae 5:293 Torulopsis sp. 5:292;21:758 Tosic acid 19:208 2'-O-Tosyl-5'-O-trityladenosine 19:519 Tosylation 6:287,288,11:359,19:518; 22:208 of nucleosides 19:516 y-Tosyl-N-isobutylcrotonamide 21:383 c0-Tosyloxy-c~-phenylthiocrylontriles 6:540 Total fatty acids 24:1009-1015 fatty acid derivatives of 24:1015 Total Ion Chromatogram (TIC) 19:766 Total plasma cholesterol 30:95 effect of chitin-chitosan on 30:95 Total synthesis 26:66,67,69,71,72,75, 77,78,87,90;28:367,502,661,672, 687,709;29:148 carbaaldopyranoses synthesis by 29:471 of (-)-acetomycin 24:5 of (-)-anastrephin 24:5 of (-)-epianastrephin 24:5 of (-)-verrucarol 24:3,25-47 of (+)-eremantholide A 24:5-7, 11,13 of (10Z, 15Z)- 10,15-eicosadienoic acid 26:90 of (4E,7S)-(-)-7-methoxy-4-tetra decenoic acid 26:78 of (5Z,9Z)-5,9-hexacosadienoic 26:82 of (R)-22-methyl-5,9-octacosadienoic acid 26:87 of (R)-2-methoxyhexadecanoic acid 26:78 of (Z)-2-methoxy-5-hexadecanoic acid 26:77 of 10,13-dimethyltetradecanoic acid 26:67 of 11-methyl- 12-octadecenoic acid 26:69 of 25-oxa-25-phospha-vitamin D3 9:509-528;24:3,5,7,11-15,25-47
of 7-methyl-6(E)-hexadecenoic acid 26:71 of 7-methyl-6-octadecenoic acid 26:72 of 9,13-dimethyltetradecanoic acid 26:66 of destomic acid 4:130 of ecdysteroids 29:17 ofent-calyculin A 26:1234, 1235-1239,1240 oferythromycin A 12:53,54 oferythronolide A 12:46-53 of galantinic acid 4:127 ofhalipanicine 28:661 of koumidine 15:493 of kuehneromycin A 29:148 of methyl (Z)-2-methoxy-6-hexa decenoate 26:75 of Mniopetals 29:148 ofnagilactone F 28:502 of Na-Methyl-D ~8-isokoumidine 15:493 ofparaherquamide A 28:331,367 of pateamine 28:709 of phorbol 12:265-272 of purpurosamine C 4:123 ofrifamycin W 12:46,47 of stellettamine 28:687 of suvanine 28:672 of vitamin D3 9:510 Totarane 25:241 Totarol 2:403;29:103 activity in EBV bioassay system 29:103 Totarol derivative 9:297 Totipotency 7:94-96 of cell cultures 7:94-96 Totoacetate 7:464 Tournefolal acid 30:223 structure of 30:223 Tournefortiolide derivatives 7:233 from Artemisia tournefortiana 7:212 Touroacidins A and B 25:797 Tovomita krukovii 29:578 Toxadocia cylindrica 28:711 Toxadocial A 28:711 as sulfated long chain alcohols
817
28:711 thrombin inhibition by 28:711 Toxadocial B 28:711 as sulfated long chain alcohols 28:711 thrombin inhibition by 28:711 Toxadocial C 28:711 thrombin inhibition by 28:711 Toxic chemical 30:762 dioxin as 30:762 polychlorinated biphenyl (PCB) as 30:762 Toxic free heine 25:327 Toxic xenobiotic 25:935 Toxicity 7:279-282;24:153 of asterosaponins 7:303 of fumonisine 13:532 of holothurins 7:279-282 of quassinoids 7:388,389 to reproductive organs 27:311 Toxicity assays 26:790 for extracellular promastigote 26:790 Toxicity effects 27:444 on animals 27:444 Toxicity study 27:306 of stevioside 27:306 Toxiclona toxius 28:675 toxicol A from 28:675 toxiusol from 28:675 Toxicokinetics 23:19 Toxicological activities 21:4 Toxicological responses 21:99 Toxicological studies 27:301 Toxiferine 21:52,102;25:528 as immunosuppressive drug 25:528 Toxigenic moulds 9:201-203 Toxin 5:403,404,411 ;9:9-11,209-211 of echinoderms 7:265-316 Toxisterol-B 2:162 Toxocara canis 17:379;24:714; 26:470,471,474,887 Toxocara mystax 26:471 Toxoplasma 26:783,804 Toxoplasma gondii 13:183;26:835 Toxotrypana curvicauda 5:239,252 2-methyl 6-vinyl-pyrazines of 5:222
Toyocamycin 15:459;24:547,548 antiviral microbial-derived compound 24:547,548 TPA 25:55,59 inhibitory effects on 25:55 induction of EBV-EA activation by 25:59 TPA induced edema (TPA) 25:45 TPA induced inhibition 25:45 role of ornithine decarboxylase (ODC) 25:45,66 TPA induced ornithine decarboxylase inhibition (ODC) 25:45,46 TPA induced skin tumors 25:46 TPA stimulated 32pi incorporation 25:60 in HeLa cells 25:60 TPA-induced assay 25:58,61 TPA-induced ear edema 25:57,58 TPA-induced edema inhibition (CRO) 25:45 TPA-induced inflammation 25:47,48,63 TPA-induced inflammatory edema 25:56 TPA-induced ODC accumulation 25:60 TPA-induced secretion 12:397 from pancreas islets 12:397 of insulin 12:397 TPA-mediated DNA 25:937 TPA-responsive element 15:441 TPA-type tumor promoters 25:61 TPSTe 4:269 as condensing agent 4:269 Tracheal mites 28:389 effects of vegetable oils on 28:389 (+)-Trachelanthamidin 19:145 isolation of 19:145 synthesis of 19:145 Trachelanthamidine 1:246,228,232 synthesis of 1:246,228,232-237, 240,246,248-250,259,260,325, 326,339;3:51 (+)-Trachelanthamidine 13:483 Trachelanthamine 1:267 synthesis of 1:267 Trachelanthic acid 1:260,261,270
818
Trachelogenin 24:742 inhibition of replication of HIV- 1 24:742 Trachelogenin 5:522,531,533; 26:192,233 (-)-Nor-Trachelogenin 26:474 Tracheloside 5:532,533 O-methylation of 5:532,533 O-glucosylation of 5:532,533 Trachelospermum asiaticum Nakai var. intermedium 5:505,515,521,526,545 Trachelospermum jasminoides 26:233 arctigenin from 26:233 matairesinol from 26:233 nortrachelogenin from 26:233 trachelogenin from 26:233 Trachycladine 25:775 Trachycladus laevispirulifer 25:775 (-)-Trachyloban- 19-oic 26:812 Trachyloban- 19-oic acid 29:103 activity in EBV bioassay system 29:103 trans-communic acid methyl ester activity in EBV bioassay system 29:101 Trachylobium verrucosum 25:252 Trachyopsane 25:848,851 Trachyopsis aplysinoides 28:660 Trachyopsis halichondroides 25:70;428:700 26-norsokotrasterol sulfate from 28:700 Tradescantia multiflora 25:382 Traditional medicine 17:113 Tragacantha Bunge 27:444 Tragacanthin polysaccharide (PS) 30:411 effect on liver 30:411 effect on liver infection scores 30:411 effect on mortality 30:411 effect on serum transaminase 30:411 effect on spleen virus titer 30:411 from Astragalus brachycentrus 30:411 Tragopogon saponins 15:191 Tramesanguin 26:1012
Trametes cinnabarma 26:1012 Tranquillizers 21:101 Tranquillizing activity 30:200 of droperidol 30:200 Trans aldehydo lactol 8:22,23 Trans, trans-ceratospongami d 25:902,903 Trans- 1,2-dihydroxylimonene 25:150 (E)- Trans- 1-hydroxy- 10-vinyl-2cyclodecene 8:196,197 synthesis of 8:196,197 (Z)- Trans- 1-hydroxy- 10-vinyl-2cyclodecene 8:196,197 synthesis of 8:196,197 trans- 1-Propenyl 2-propene thiosulfinate 23:459 trans-2-aryl-2,3-Dihydrobenzo furan moiety 27:767 Trans-3 '-hydroxycotinine 22:12 Transacetalation 8:287,288;11:82, 83,109 acid-catalyzed 14:654 intramolecular 14:654;11:109 Transacylase 25:501 Transannular [2,3]-Wittig rearrangement 8:195-201 synthesis of costunolide 8:195201 synthesis ofhaageanolide 8:195201 Transannular [4+2] cycoaddition 5:796, 797 Transannular acylation 3:81,82 of sulfur stablized carbanions 3:81,82 medium ring formation by 3:81,82 Transannular cyclization 13:440 Transannular deprotonation 10:222 Transannular Diels-Alder reaction 8:187-195 Transannular ketal cyclization 11:59 Transannular oxidation 29:173,174 in pisiferic acid synthesis 29:173,174 Transannular reaction 8:175,19:66,418 Transannular SN 2 cyclization 15:500 Trans-anti-trans-anti stereochemistry 8:188
819
(+)-Trans-chrysanthemic acid 16:221,257,258 (+)-Trans-cognac lactone 16:693 Transcription initiation 5:580 Transcriptional activity 30:496,497 of 1c~,25(OH)2D analogue 30:497 Transcriptional factor 25:470 Transcriptional inhibitors 25:461 Transcylase 25:502 Transducin 25:521 Trans-epoxysqualene 25:181 Transesterification 1:267,8:288,292; 21:168 enantioselective 1:685;13:53,54 enzymatic 13:55 oftricyclic lactones 12:30 of propane- 1,3-diols 13:53-55 trans-Farnesyl diphosphate 21:230 Transferase 7:58;17:480 Transferrins 9:537,555 Transformation 23:488,491,503,511; 24:53-62,72,73,78,80,90;27:74 biomimetic 11:292-295 hobartine-aristoteline 11:292-295 of 9-hydroperoxy- 10,12,15octadecatrienoic acid 27:74 of artemisin 24:78 ofbacogenin A1 23:503,511 of bile alcohols 17:217 ofcleomeolide 23:488,491 of oxetanocin A 10:586,587 of quinocarcin 10:119,120 of saframycins 10:101-103 of santonin 24:80,90 of santonin to sesquiterpenes 24:53 Gl0-Transgenic plant 25:661 Transglycosylation 7:54,55,61 Transilin 7:228 (+)-Trans-isopiperitenol 17:605 Transition probabilities 2:57,58 Transition state analogue 7:49 of lysozyme 7:49 tetrasaccharides as 7:49 Transition states in synthesis 29:161 of kuehneromycin A 29:161 Transketalization 1:415,417,457
Translactonization 8:21,29 intramolecular 13:159 Translation inhibitors 21:98 Transmethylation 2:53 inhibition of 1:408 in FAB spectra 2:53 Trans-piceid 22:611,617,619,622 Trans-pinocarveol 23:819;25:154 Transplantable Meth A tumor 30:776 Transplanted murine rumor cell lines P 388 30:27 pironetin against 30:27 trans-p-Methyoxycinnamate 23:818 1,3-Transposition 4:165 of allylic system 4:165 Trans-resveratrol 22:611,619,621,622, 627
Trans-resveratrol-O4-fl-glucoside 22:611,619
(+)-Trans-sesquifenchene 16:236 D-(+)-Trans-sobrerol 25:152 Trans-squalene oxide 25:182 (+)-Trans-whiskey lactone 16:695 synthesis of 16:695 Transylidation 4:560,563,564 Trapajaponica 23:405 Trapa quadrispinosa 24:273 Trapaceae 23:405 Trapanin A 23:405 Trapanin B 23:405 TRAP-induced ELAM- 1 expression 30:70 inhibition of 30:70 Tras Glogi area 25:114 Traumatic acid 27:75 generation of 27:75 Traxacum officinale 25:391 Tr-B 20:492,493 Treatment 26:787-788,804;30:597 of Chagas disease 26:787 of cryptosporidiosis 26:788 of malaria 26:804;30:597 of postpartum hemorrhage 30:597 of morning sickness 30:597 Trechonolide A 20:181 a,c~-Trehalase 7:32,69;10:498 Trehalase 7:50,58,60,69;8:318-322
820
ot,cf-Trehalose 14:148 a,c~-Trehalose 8:347,348;10:499; 13:216,223 Trehalose derivative 6:40,401 Trelox 25:933 Trema guineensis 22:534 for epilepsy 22:534 Trema orientalis 22:534 for epilepsy 22:534 Tremaster novaecaledoniae 15:45,72,75,96 Tremasterol A, B and C 15:72 Trematode (fluke) 12:7 Tremella mesenterica 5:288,289,307 Tremella sp. 5:288 Tremorgenic toxins 24:1060 Trestatin A 10:517 Trestatin B 10:517 c~-amylases inhibitor of 10:517 amylo-c~- 1,4-a- 1,6-glucosidase 10:517 from Streptomyces dimorphogenes 10:517 Trewia nudiflora 23:70 Triabunnine 9:195;11:299,300 Triacetic acid lactone 25:498 ( IS)-( 1,3,6/2)- 1,2,3-Triacetoxy-4acetoxy-methyl-6-azidocyclohex-4ene 10:507 Triacetyl-l,2,-dipalmitoyl-3-O-(6'-sulfo2-2',3',4'-D-quinovopyranosyl) glycerol 25:868 Triacontanal 7:189 Triacontanol 21:240 2'-/3'-Trialkyl silyl ribonucleosides 14:285 silyl migration in 14:285 Trialkylaluminium compounds 1:624, 625 addition to a,[3-alkynyl acetals 1:624,625 addition to c~,[3-unsaturated acetals 1:624,625 diastereoselective addition of 1:624,625 Trialkylalumnium 6:428 Trianion 1:13 of indole-3-acetic acid 1:13
Tribenzo[a,c,e] cycloheptatrien-5-one 11:125 from diethyl 2,2'-bi-1-benzoate 11:125 synthesis of 11:125 Tribenzotropone 11:125 D-2,3,6-Tribenzyl-myo-inositol 18:397 Tribolium castaneum 9:299; 21:612;23:66 Tribolium confusum 24:101 Tribophyton mentagrophytes 21:758 Tribrominated bisindole alkaloid 25:765 1,8-Tribromo-3,4,7-trichloro-3,7dimethyl-1, 5-octadine 25:783 1,4,10-Tribromo-3-chloro-7(14) ene-c~chamigrene 5:217 113,4[3,10[3-Tribromo-3-chloro-7( 14)ene-c~-chamigrene 9:81 Tribulus terrestris 24:273;26:259 tribulusamide A from 26:259 tribulusamide B from 26:259 Tribulusamide A&B 26:259 (E)-2-(Tributylstannyl) ethenyllithium 21:400 Tributyltin radical 1:490 addition to olefin 1:490 (Z)-[3-Tributyltinpropenamide 21:392 (Z)-Tributylvinylstannanes 10:162 cross-coupling reactions with 10:162 Tricarbocyclic bridged systems 6:74-86 Tricarbocyclic epoxide 6:37,38 by Saegusa ring expansion 6:37,38 (+)-dactylol from 6:37 synthesis of 6:37,38 Tricarbocyclic fused systems 6:38-58 stereoselective synthesis of 6:3858 Tricarbonyl (diene) iron complex 12:280 Tricellaria ternata 17:92 Trichia floriformis 29:232 as myxomycete species 29:232 arcyriaflavin B from 29:232 2,4-dihydroxynaphthoquinone chromophore of 29:232
821
Trichia varia 29:236 Trichilia emetica 20:492,493 Trichilia glabra 30:411 anti-polio virus activity of 30:411 Trichilin-4 20:492 Trichiline-A 20:493 Trichinella spiralis 22:401 ;26:483 Trichlorinated orcinol 25:786 Trichloroacetamidate 6:276,277 from D-glucose 6:276,277 3-Trichloroacetamido-3-C-vinylderivative 10:421 Trichloroacetimidate method 4:207-209 condensation of 4:207-209 in oligoheptose synthesis 4:205, 206 ~-Trichloroacetimidates 14:212,213 c~-Trichloroacetimidates 14:212,213 Trichloroethyl carbamate 1:71 Trichloroleucine metabolite 25:801 Trichloromethylperoxyl 22:322 Trichocolea tomentella 2:278 Trichocoleopsis sacculata 2:278,279 Trichocoleopsis sp. 2:90 Trichoderma 22:251,627 Trichoderma hamatum 21:240 Trichoderma harzianum 8:352;21:197, 198,199,201,213,214,227,223,225, 233 cyclonerodiol from 21:226,227 harziandione from 21:209,234 harzianins HA from 21:225 tetramic aicd from 21:216 4-thiocellobiose from 8:352 trichoharzin from 21:211 trichokindins from 21:225 trichorozins from 21:225 trichorzianines from 21:225 Trichoderma koningii 21:198,229 cyclonerodiol from 21:226 gliodeliquescins from 21:225 ergokonin A and B from 21:237 heptelidic acid from 21:229 trichoacorenol from 21:231 trichokonins from 21:225 trikoningins KA from 21:225 trikoningins KB from 21:225
Trichoderma lignorum 8:352;21:182 xylanases from 8:352 Trichoderma longibrachiatum 21:206, 212,225;25:725 Trichoderma polysporum 21:212,227 polysporins from 21:225 tetrahydrofura analogues from 21:227 trichosporins from 21:225 trichopolyns from 21:225 Trichoderma pseudokoningii 21:225 harzianins HK from 21:225 Trichoderma reesei 8:348,351,21:225; 23:128;25:308 cellobiohydrolases from 8:348,351 cellobiohydrolase A from 8:351 cellobiohydrolase B from 8:351 Trichoderma saturnisporum 21:225 saturnisporins from 21:225 Trichoderma sp. 5:368;7:406;21:191, 196-198,202,203,212,213,215,221, 223,224,226,227 ;25:155 ;26:482, 1128 Trichoderma virens 21:232 4-thiocellobiose from 8:352 Trichoderma viride 21:191,197,212, 221,223,225,229,234,237 ergokonin A and B from 21:237 trichodermin from 21:232 trichotoxins from 21:225 suzukacillins from 21:225 Trichodermin 6:233 Trichodermol 24:25,26 (d/)-Trichodiene 10:307-309 synthesis of 10:307-309 Trichodiene 6:247-250;9:212214;13:524 Trichodiene-derived compounds 6:213,214 Trichodienoids 13:524,525 Trichodiol 6:247,248;13:524 Trichodonin 15:112,162 Trichoguattine 16:515 from Guatteria trichostermon 16:515 Trichokaurin 15:173 from Rabdosia longituba 15:173 Tricholma giganteum 23:126,134
822
Tricholomoidei 17:198 Trichomans vaginalis 22:625 Trichomes 22:75 Trichommonas foetus 2:293 staurosporine against 12:397 Trichomonads 22:617 Trichomonas gallinae 2:294 Trichomoniasis 12:397;22:625 Trichomycetes 9:202;22:246 Trichonine 10:152 Trichophylline 9:190-192 X-ray crystal analysis of 9:192 Trichophyton rubrum 26:1159 Trichophyton granulosum 5:294 Trichophyton interdigitale 5:294, 298,598;12:401 Trichophyton mentagrophytes 2:446; 12:401 ;20:28,30,31 ;21:602;22:627, 628 ;23:199;25: 780;26:227,673; 28:476 isomagnolol from 26:227 magnolol from 26:227 Trichophyton rubrum 5:294,236; 12:401,21:602;22:627 Trichophyton schonleinii 5:294 Trichophyton sp. 5:294,328; 21:396;26:1127,1128 Trichophyton tonsurans 12:401 Trichoplusia 5:832 Trichorabdal A 15:142 13C-NMR of 15:158 from Rabdosia trichocarpa 15:175 from Rabdosia weisiensis 15:175 ~H-NMR of 15:150 Trichorabdal B 15:142 13C-NMR of 15:160 from Rabdosia trichocarpa 15:175 ~H-NMR of 15:151 Trichorabdal C 15:143 13C-NMR of 15:160 from Rabdosia trichocarpa 15:175 IH-NMR of 15:151 Trichorabdal D 15:144 13C-NMR of 15:161 from Rabdosia trichocarpa
15:175 1H-NMR of 15:153 Trichorabdal E 15:144 from Rabdosia trichocarpa 15:175 ~H-NMR of 15:152 Trichorabdal F 15:143 from Rabdosia trichocarpa 15:175 ~H-NMR of 15:152 Trichorabdal G-acetate 15:143 from Rabdosia trichocarpa 15:175 ~H-NMR of 15:152 Trichorabdal H 15:112,143,162 13C-NMR of 15:160 from Rabdosia trichocarpa 15:175 lH-NMR of 15:152 Trichorabdonin 15:144 13C-NMR of 15:161 from Rabdosia trichocarpa 15:175 IH-NMR of 15:153 Trichormus var. P-9 26:359 in agar-diffusion assays 26:359 Trichosanthes anguins L. 22:534 for epilepsy 22:534 Trichosanthes kirilowii 13:655,660; 22:124 c~-Trichosanthin 13:655 Trichosanthin 13:660 Trichosporon aculeatum 5:283,292 Trichosporon cutaneum 5:292,294 Trichosporon fermentans 5:292 Trichosporon inkin 5:294 Trichosporon sericeum 5:294 Trichosporon sp. 5:292;25:150 Trichosporon undulatum 5:294 Trichostatin 21:388 Trichostatin B 21:388 Trichostatin C 21:388 Trichostrongylus colubriformis 26:429, 440,443,453,461,472,484,490,491 ;2 8:349 Trichothecene complex 30:751 of antibiotics 30:751 Trichothecene mycotoxins 13:517
823
Trichothecenes 9:203,205,207-213; 10:307;13:524 ;21:232;30:751 biosynthesis of 6:249-259 fungal toxins 30:751 phytotoxicity of 30:751 role in mycotoxicoses 30:751 role in plant pathogenicity 30:751 synthesis 9:213-247 toxicity toward eucaryotic organisms 30:751 Trichothecinol A 29:88 activity in EBV assay system 29:88 Trichothecinols B 29:88 activity in EBV assay system 29:88 Trichothecium 21:233;26:464 Trichothecium roseum 10:307;29:88 Trichothecolone 6:237,239 Trichoviridin 21:362 Tricin 7:228 Triclisia sp. 26:824 Tricophyton mentagrophytes 9:297; 26:228 Tricophyton rubrum 26:228 Tricuspidatol A 26:568 Tricycic diterpenes 6:108 Tricyclic aromatic glutarates 11:121,122 pentacyclic derivatives 11:121,122 Tricyclic gephyrotoxins (perhydrobenzoindolizidines) 11:244 Tricyclic natural products 6:74 by intramolecular cycloalkylation 6:74 synthesis of 6:74-86 seco-(11,12)-12,13-Tricyclic quinolizidines 27:265 dehydromultiflorine 27:265 seco-(11,12)-5,6-dehydromultiflorine 27:265,266 Tricyclic resin acid 15:16;27:22 Tricyclic xanthone 25:349 Tricyclo [3.2.1.02'7] octane 8:419 Tricyclo [5,3.1.01'5] undec-9-ene-8,11diones 8:163 Tricyclo [5.2.2.0 !'5] undecane 8:426,427
Tricyclo [5.3.0.0 2"6]decane group 6:40 spatane diterpenoids in 6:38,39 Tricyclo [6.3.0.046] undecane group 6:42-50 Tricyclo [6.3.0. 3'7] undecane 13:3,4,37 Tricyclo [6.3.0. 4'8] undecane 13:3, 13:4, 13:37 Tricyclo [7.1.0.016] decane group 6:4042 Tricyclo [8.1.0.0 2"6]undecane group 6:50.51 Tricyclo [9.3.0.0] tetradecane 12:246 Tricyclo [9.3.0.038] tetradecane group 6:52-54 Tridacna crocea 23:178 Tridacna maxima 28:652 arsenic-containing sugar sulfate from 28:652 Tridecagalacturonides 25:486 n-Tridecane 21:600 Tridecapeptide polydiscamide A 25:867 3-Tridecyl phenol 2:280,281 6-Tridecyl salicyclic acid 2:280,281 Tridensone 18:640-643 from Bazzania tridens 18:639 Tridentata marginata 25:896;28:646 tridentatol A from 28:646 tridentatol B from 28:646 tridentatol C from 28:646 Tridentatol A,B and C 25:895,896 1,2,4-Trideoxy- 1-nitro-2-phosphinyl-Lpentitol 6:357 2,6,7-Trideoxy-2,6-imino-D-glycero Dmanno-heptitol 11:467 synthesis of 11:467 2,6,7-Tride oxy-2,6-imino-D- gl yc ero-Dgluco-heptitol 11:467 synthesis of 11:467 2,3,4-Trideoxy-DL-glycerohexopyranose 7:35,36 endo-dextranase reaction with 7:35,36 2,3,13-Trideoxyevoninol 18:745 3,4,13-Trideoxyevoninol 18:745 2,3,13-Trideoxyisoeuoniminol 18:746 Trideoxynucleosides 4:525 synthesis of 4:525 Tridesmosides 15:188 Trideuteriolactone 8:303,304
824
Trideuteriopyrocatechol 8:303 8',8', 8'-Trideutero-ABA 27:348 Trididemnic acid A 23:268 Trididemnic acid B 23:268 Trididemnum cyanophorum 4:102; 5:427,428;10:244,250,251,252,262, 294 Trididemnum palmae 10:252 Trididemnum solidum 4:102;10:245, 250,252,253;25:118 Trididemnum sp. 5:422;10:245;12:303, 477 ;21:252;25:819,820;28:638 didemnine A from 12:477 didemnine B from 12:303 from Guam 28:638 shermilamine A from 28:638 Tridiemnum genus 17:23 1,4,6-Trien-3-one 11:379,380,388 1,5,7-Trien-3[3-ols 11:379,380 (E,E,E)-Triene 8:188-190 synthesis of 8:188-190 (Z,E, E)-Triene 8:188-190 synthesis of 8:188-190 Trienomycin 11:189 from Streptomyces sp. 11:189 Trienomycin 23:54 Trienomycins A 23:77 (+)-Trienomycin A 23:78 absolute stereochemistry of 23:78 Trienomycin B 23:77 Trienomycin C 23:77 Trienomycin D 23:77 Trienomycin E 23:77 Trienomycin F 23:77 3-Trienoylpyrrol-2(5H)-ones 13:140 Trienylpyrrol-2(SH)-one 13:122, 123,133,134 Triethyl silane 3:218 reduction ofhemiketal 3:218 Triethylammmonium formate 3:184 Pd2 catalysed reduction 3:184 Triethylsilyl silyl ethers 11:339 bis (Triethylsilylacetylene) 10:249 Triethylsilylation 11:363,364 3-Triethylsilyloxy- 1,4-pentadiene 12:242 to 2-methylene- 1,3-dithiane 12:242
Triflic acid 21:746 Triflouim sp. 25:667 Triflouroacetic acid (TFA) 25:6,434 Trifluoperazine 25:487 Trifluorinate [3-ionylideneacelic acid 27:346 of 16,16,16-trifluororetinal 27:346 8'-Trifluorinated analog 27:347 8',8',8'-Trifluoro-ABA 27:346 from methyl ester 27:346 Trifluoroacetic acid 21:143 Trifluoroacetoxyselenylation 12:473 3-Trifluoroacetylallohobartine 11:318, 319 from allohobartine 11:318,319 N-Trifluoroacetyl-L-acosamine 4:150,151 synthesis of 4:150,151 N-Trifluoroacetyl-L-daunosamine 4:150,151 synthesis of 4:150,151 2-[bis(2,2,2-Trifluoroethoxy)phosphoryl]- 1,3-dithiane 30:459 Trifluoromethanesulfonates 8:316 TrifluoromethanesulphoxJic acid 26:1162 (+)- ot-Trifluoromethyl-ctmethoxyph~- vl acetic acid 12:478 Trifluoroperazme 12:387 protein kinase inhibitor of 12:387 Trifluralin 25:669 Trifluridine 24:487 as anti-viral agent 24:487 2,2,2-Trifluroethylhydrazonemethyl 9deoxy-9-oxo-ot-apopicropodophyliate 26:195 4-O-Triflylgalactoside derivative 8:330, 331 synthesis of 8:330,331 Trifolium repens 26:696 Trifolium subterraneum 29:577 14-endo-Trig cyclization 13:589 5-exo-Trigaryl radical-alkene cyclization 3:327,328 Triglyceride lipase 25:523 Triglycosides 7:270,273,275,286,287
825
Trigonella foenumgraecum 21:671; 26:1139,1141,1268;27:277;28:425 Trigonoside I 25:192,224 Trigonoside II 25:194,224 Trigonoside III 25:194,224 Trihaloalkyl protecting group 4:286 removal of 4:286 Triheptoses 4:196 in Aeromonas salmonicida 4:196 in Enterobacteriaceae 4:196 in Pasteurella multocida 4:197 in Phenylobacterium immobile K2 4:196 Trihydroxy fatty acids 27:77 enzymic generation of 27:77 1c~,3[3,4[3-Trihydroxy-(5 c~,7a, 11 [3H,10c~ methyl)-eudesman- 12,6c~-olide 27:553 2,3,22 [~-Trihydroxy-24-29-dinor1,3,5(10), 7-friedelatetraene-6,21dione-23-al 30:679 13C-NMR experiment of 30:679 HREIMS of 30:679 IR absorption of 30:679 molecular formula of 30:679 ROESY experiment of 30:679 structure of 30:679 2,3,22 [3-Trihydroxy- 24- 29-dinor- 25 (9-->8)- 1,3,5(10), 7- frie de latetraene21-one-23-al 30:680 13C-NMR of 30:679 tH-NMR spectrum of 30:679 HMBC of 30:679 HMQC experiment of 30:679 molecular formula of 30:679 2-[3 a,7 a, 11 a-Trihydroxy-24-oxo-5flcholan-24-yl] amino ethanesulfonate 25:872 5,3',5'-Trihydroxy-3,6,7,4'tetramethoxyflavone 5:757 ( 1S)-2,3,4-Trihydroxy-5(hydroxymethyl)- 1-cyclo-hexy-1 amine [5 a-carba-ot-Dglucopyranosylamine] 13:195 2 c~,313,6p-Trih ydro xy-5 c~-pre gn ane- 20one 18:532,532 5,8,4'-Trihydroxy-6,7,3'trimethoxyflavone 5:628,655
5,3',4'-Trihydroxy-6,7,8trimethoxyflavone 5:655 5,8,4'-Trihydroxy-6,7-dimethoxyflavone 5:628,629 5,3',4'-Trihydroxy-6,7dimethoxyflavone 5:655 5,6,4,-Trihydroxy-7,3-dimethoxyflavone 5:655 la,3 [~,10c~-Trihydroxy-7ot, 11 [3Hgermacra-4Z-en- 12,6ot-olide 27:563 3fl,6a, 16fl-Trihydroxy-9,19-cyc lolanost-24-ene 25:185 3fl, 6 a, 16fl-Trihydroxy-9fl,19-cyclolanost-24-oxo,25-ene 25:185 6,12,14-Trihydroxyabieta-6,18,11,13tetraene 20:670 1,3,5-Trihydroxyacridin-9-one 13:352 synthesis of 13:357,358 ent-3[3,16or, 17-Trihydroxyatisane 29:100 activity in mam-2 assay system 29:100 1c~,25S,26-Trihydroxy-cholecalciferol 10:69 synthesis of 10:69 l[3,6c~,8c~-Trihydroxycostic acid methyl ester 27:558 Trihydroxyethylated rutoside 22:320 1[3,4c~,6ot-Trihydroxy-eudesm- 11 -en6o~,12-olide 27:553 3,3',4'-Trihydroxyfl avone 25:544 5,7,4'-Trihydroxyflavone 27:842 3,5,7-Trihydroxyflavones 22:614 Trihydroxyicosadienoic acid 9:577 (+)-(6S,7S, SR,SaR)-Trihydroxyindolizidine 12:347,348 enantiospecific synthesis of 12:347,348 synthesis of 12:347 6,7,8-Trihydroxyindolizidine 12:348 from methyl 2-azido-4,6-Obenzylidene-2-deoxyot-D-altropyranoside 12:348 synthesis of 12:348 1,7,8-Trihydroxyindolizidine 27:514 5,6,7-Trihydroxylated coumarin 5:516,517,520
826
Trihydroxylean- 12-ene saponins 25:179,191 4,5,6-Trihydroxynorleucine 14:192 2[3 (3 ,4, 5-Trihydroxyphenyl) alanine (Topa) 23:241 2,4,5-Trihydroxyphenylalanine 26:1266 3,4',5-Trihydroxystilbene 27:767 cis-3,5,4'-Trihydroxystilbene 4'- O- [3-D(6-O-galloyl)- glucoside (stilbene glycoside) 29:589 effects on PEP 29:589 Trihydroxystilbene reseratrol 26:507,511 /3,16fl,22 a-Trihydroxytaraxastene 25:623 1,24,25-Trihydroxyvitamin D2 9:513 1a,24-R,25-Trihydroxyvitamin D3 9:521 6,7,8-Trihyroxylated coumarin 5:516,517,520 Triiodothyronine 27:314 2,4,6-Triisopropylbenzenesulfonyl chloride 4:269 as condensing agent 4:269 2,4,6-Triisopropylbenzenesulfonyl chloride 4:269 as condensing agent 4:269 2,4,6-Triisopropylbenzenesulfonyl-4nitro-imidazole TPSNI 4:269 as condensing agent 4:269 2,4,6-Triisopropylbenzenesulfonyl-4nitro-imidazole TPSNI 4:269 as condensing agent 4:269 Trijugin A 2:267,268;9:94,95 Trijugin B 2:267,268 Triketones 6:445,446 reductive amination of 6:445,446 Trillium glycosides 2:443 antifungal activity of 2:443 Trillium grandiflorum 2:443;23:343 Trillium smalii 21:662 Trillium tschonoskii 2:443 Trilobatin 15:31 ;27:17,33,34 structure of 27:34 Trimer 5:754 of plumbagin 5:754 ofplumbazeylanone 5:754,756 Trimethoxy benzohydroheptalone 3:289,290
synthesis of 3:289,290 (-)-trans-2-( 3 ",4 ",5 "-Trime tho x y
b enzyl)- 3-(3 ',4 '-ethylene dioxyenzyl) butyrolactone 26:192 3,4,6-Trimethoxy phenyl-O-glucoside 27:410 2,4,6-Trimethoxyacetophenone 9:288, 289 3,4,5-Trimethoxycinnamate 18:580 6,7,8-Trimethoxycoumarin 26:317, 332-334,342 5,6,7-Trimethoxyflavone 5:640,652, 654;7:413 3,5,7-Trimethoxyflavone 5:652-654; 7:413 5,7,8-Trimethoxyflavones 5:640 2,4,5-Trimethoxystyrene 9:402 Trimethyl decalone 6:19,20 by Robinson annulation 6:19,20 from ethyl vinyl ketone 6:19 from 2-methyl- 1,2-cyclohexadione 6:19 in euryfuran synthesis 6:20 in pallescensin-A synthesis 6:20 synthesis of 6:19,20 O, O, O-Trimethyl korupensamine A and B 20:450 Trimethyl orthoacetate 14:725 corynan-17-oic acid methyl esters from 14:725 Trimethyl orthoformate 1:448,449 methylation with 1:448,449 Trimethyl silyl enolate 14:572,573 ozonolysis of 14:572,573 piperidine derivative from 14:572,573 l',3,3'-Trimethyl-l,2'-biazulene 14:336 3,7,11-Trimethyl- 1,6,10-dodecatrien-3ol 25:161 (Z)-3,7-11-Trimethyl- 1,6-dodecadiene3,10,11,triol 25:164 2,6,10-Trimethyl-2,5-epidi-oxy-7,10epoxydodeca-11-en 27:594 (5S, 6S,7S, 10R)-2,6,10-Trimethyl-2,5epidioxy-7,10-epoxydodeca-3,11dien-5-ol 27:594 6-(3,7,11-Trimethyl-2,6,10dodecatrienyl)-2-metho xy-phydroquinone 15:294
827
2-(3,7,11-Trimethyl-2,6,10dodecatrienyl)-hydroquinone 15:294 (2E,6E)-3,7,11 -Trimethyl-2,6dodecadien- 1,10,11-triol 25:166 1,1,2-Trimethyl-2-phenyl cyclopentane 8:6,7,10,13 2,2,5-Trimethyl-5-hexenal 6:45,46 (+)-Ag~l2)-capnellene from 6:45,46 1,3,8-Trimethylallantoin 22:6 6,4,4'-Trimethylangelicin 21:617 Trimethylanilinium hydroxide 21:145 4,6,8-Trimethylazulene 14:341,342 oxidation of 14:341,342 [3,3-(Trimethylendioxy) propyl] magnesium bromide 11:284,285 Trimethylpyrrocorphin 9:604 2-(Trimethylsiloxy) furan (TMSOF) 11:451,453 2-Trimethylsiloxyfuran 3:167 3-exo-Trimethylsilyl camphor 4:663, 664 N-Trimethylsilyl cinnamylidene imine 4:455,457 Trimethylsilyl cyanide 1:156 in glycosylcyanide synthesis 3:210-212 Trimethylsilyl derivative 4:223 in nucleosides synthesis 4:223 Trimethylsilyl enolate 14:572,573 ozonolysis of 14:572,573 piperidine derivative from 14:572,573 Trimethylsilyl esters 4:564 acylation of phosphonium ylides 4:564 Trimethylsilyl intermediates 4:394 in prenylation methods 4:394 N-Trimethylsilyl iodohydrin 1:277 Trimethylsilylmethylation 1:249 Trimethylsilyl triflate (TMSOT) 12:419,420 bis-(Trimethylsilyl) hydrogen phosphate 8:69 1-Trimethylsilyl)imidazole 21:740 2,3-bis-[(Yrimethylsilyl)oxy butadiene 12:377
1,2-bis-phenylhydrazone from 12:377 with maleimide 12:377 2-(Trimethylsilyl)oxy] butadiene 12:377 2-Trimethylsilyl- 1,3-dithiane 12:156 N-Trimethylsilyl-3-(trimethylsily) propynaldimine 4:457 Trimethylsilyl-3-butyn- 1-ol 12:473 2-Trimethylsilyl- 1,3-dithiane 12:156 2-(Trimethylsilyl)oxy] butadiene 12:377 Trimethylsilylated compound 30:239 NMR spectrum of 30:239 Trimethylsilylation 1:272,273 3-endo-Trimethylsilylcamphor 4:663, 664 Trimethylsilyldiazomethane 4:91,92 esterification of 4:91,92 Trimethylsilylisocyanate 3:309 N-acylation of indoline 3:309 Trimethylsilylmethylation 1:249 Trimethylsilyloxy butadiene 14:751,752 with methylene glutarimide 14:751,752 4-(Trimethylsilyloxy)-[~-lactam 12:160, 161 from enolsilyl ether 12:160,161 2-Trimethylsilyloxy-6-hexadecenonitrile 26:76 2-Trimethylsilyloxybutadienes 4:581 in Diels-Alder reactions 4:581 2-Trimethylsilylthiazole (2-TST) 11:443,444 Trimethylsilyvinylalanate reagent 12:295 Trimethyltin chloride 21:147 1,3,7-Trimethylurate 22:6 Trimethysilyl iodide 21:746 Trimusculus reticulatus 17:27 Trimyristin 5:753;9:455 Trinervitermes bettonianus 21:277 8,9,10-Trinor camphor 4:656,657 C(3)-monobromination of 4:656,657 3,4,6-Tri- O-acetyl- 1,2-0cyanoarylidene-cz-D- galactose 14:224
828
3,4,6-Tri-O-acetyl- 1,2-Ocyanoethylidene-c~-D-mannose 14:229 2',4', 5-Tri- O-acetyl- 1,3,3'-tris(Nbenzyloxycarbonyl)geramine 14:146 2,3,4-Tri- O-ac etyl- 1-thio- p-Dxylopyranose 8:328,329,336 3,4,6-Tri-O-acetyl-2-O-benzyl-glycosyl bromide 14:258 2,4,6-Tri-O-acetyl-3-O-trityl-F3-Dgalactopyranoside 14:225 7-Tri-O-acetyl-6-deoxy-[3-L-galactopyranosyl) (2,3,4-theophylline 4:232 synthesis of 4:232 Tri-O-acetyl-D-glucal 6:221,222; 10:338;14:193 3,4,6-Tri-O-acetyl-D-glucal 8:343,344 2,3,4-Tri-O-acetyl-ot-D-glucopyranosyl bromide) uronate 21:170 3,4,6-Tri- O-ac etyl- [3-D-gluc op yrano syl chloride 8:360-362 3,4,6-Tri-O-benzoyl-2-phthalimido-2deoxy-c~-D-glycosyl bromide 14:242 1,2,3 -Tri- O-benzo yl-4- O-triflyl- Larabinose 8:336 1,2,3-Tri-O-benzoyl-4-S-(2,3,4-tri-Oacetyl-[3-D-xylopyranosyl)-4-thio-[3D-xylopyranose 8:336
1,3 ,5-Tri-O-benzo yl-myo-inositol
18:422 2,3,4-Tri-O-benzyl-ot-L-rhamno syl chloride 8:360,364 thermal glycosidation with 8:360,364 2,3,6-Tri-O-butyroyl-myo-inositol 1,4-5-trisphosphate 18:409 3,4,5-Tri-O-caffeoylquinic acid 25:920 1,2,6-Tri-O-galloylglucose (glucose gallic acid ester) 29:589 effects on PEP 29:589 Triol 4:166 selective silylation of 4:184 Triol oleate 21:232 3,4,5-Trioloeolglycerol 25:333 2,3,6-Tri-O-methyl 27:367
2,3,4,Tri-O-methylgalactose 15:431; 25:438 3',4',5'-Tri-O-methyltricetin 25:541 Triose-phosphate isomerase 7:30 2,4,8-Trioxabicyclo [3.3.0] octane 10:412 cis-fused 10:412 Trioxilin 9:576 Tripartol 7:204,205,224 Tripchlorolide 23:688
IV:,N5,1V:~
ylspermi d ine
29:574 effects on HIV- 1 protease 29:574 Tripdiolide 2:404,405;23:684 production of 2:407,409,411 Tripeptide 9:494 Triphenyl phenol scutigeral 30:193 analgesic action of 30:193 Triphenylmethyl phosphonium permanganate 3:182 Triphenylphosphine 11:342;22:228 Triphenylphosphonium methylide 11:351,352;22:204 deprotonation of 11:351,352 with sec butyllithium 11:351,352 N-(Triphenylphosphoranylidene)-[3alanine methyl ester 12:301 Triphenyltin hydride 6:427,428 in reductive of selenides 6:427,428 Triphophyllum peltatum 26:813,822 Triphosgene 12:113 isocyanides from 12:113 1,4,5-Triphosphate 22:25 Triphosphate isomerase 21:298 Triphyophylline 20:418,420,438 Triple-helical collagen 23:120 Triplolide 23:686 synthesis of 23:686 triepoxide analogs of 23:686 Tripneustes gratilla 7:283,284 Triprenylated flavones 29:790 dorsilurin A as 29:790 dorsilurin D as 29:791 Tripterifordin 23:687 Tripterospermum lanceolatum 27:902
829
Tripterygium doianum 30:654 3 [3-acetoxy- 11-ursen- 13cz,30olide from 30:654 Tripterygium hypoglaucum 30:646,654 hypodiol from 30:646 triptohypol D from 30:654 Tripterygium regelii 23:696 Tripterygium wilfordii 2:403,404,414, 416;7:146;18:771 ;22:109,137;132; 23:660;29:99;30:639,641,648,664, 676,689,690
3,5-di-tert-4-hydro xy-N-
isobutylbenzamide from 29:24 4-phenylamino- 1,2,3,4tetrahydroquinolines from 29:24 RG- 102240 (GS-E) from 29:23 RH-0345 (halofenozide) from 29:23 RH-2485 (methoxyfenozide) from 29:23 RH-5992 (tebufenozide) from 29:23 2[3,3[3,20R,22R-tetrahydroxy-25fluoro-5 [3-cholest-8,14-dien-6one from 29:18,19 2~,3 f3-dyhdroxy-olean- 12-ene22,29-1actone from 30:648 2 [3,22D-dihydroxy-3,21-dioxo24- c arb oxyl-29-nor- frie de lan methyl ester from 30:641 6o~-hydroxytriptocalline-A from 30:641 as anti-AIDS agent 30:639 as anticancer compound 30:639 as insecticide 29:22;30:639 as traditional medicine 30:689 bisacylhydrazines as 29:22 celastrol from 30:664 for rheumatoid arthritis treatment 30:689 for spondylitis treatment 30:689 in gene switch systems 29:23 in treatment of rheumatoid arthritis 30:639 in treatment of spondylitis 30:639 inhibitory effects of 30:690
maocrystal as 29:23,24 pristimerin from 30:664 QSAR studies of 29:22 tissue culture of 7:146 triterpenes of 7:146 triptocallic acid D from 30:648 wilforic acid A from 30:676 Tripterygium wilfordii var. regelii 30:639,642 regelone from 30:642 regeol B from 30:639 Triptinine A 23:691 Triptinine B 23:691 Triptobenzene H 23:682 Triptobenzene I 23:682 Triptocallic acid A 30:653 13C-NMR of 30:653 lH NMR of 30:653 2D NMR of 30:653 FAB-MS NMR of 30:653 IR NMR of 30:653 structure of 30:653 Triptocallic acid B 30:652 structure of 30:652 Triptocallic acid C 30:652 ~3C-NMR data of 30:652 EI-mass fragmentation pattern of 30:652 molecular formula of 30:652 Triptocallic acid D 30:648 t3C-NMR spectrum of 30:648 FAB-MS spectrum of 30:648 IH-13C COSY spectra of 30:648 tH-NMR spectroscopic data of 30:648 NOESY experiment of 30:648 stereochemistry of 30:648 structure of 30:648 Triptocalline A 30:640,641 t3C-NMR spectrum of 30:641 structure of 30:641 Triptofordin F-2 29:88 activity in EBV assay system 29:88 Triptofordin F-2 671 Triptogelin A-1 23:671,672;29:88 activity in EBV assay system 29:88
830 activity in skin-1 assay system 29:88 Triptohypol A 30:677 laC-NMR experiment of 30:677 ~H-NMR spectrum of 30:677 NOESY experiment of 30:677 Triptohypol B 30:677 laC-NMR spectrum of 30:677 Triptohypol C 30:678 13C-NMR data of 30:678 molecular formula of 30:678 structure elucidation of 30:678 UV absorption of 30:678 Triptohypol D 30:654,655 13C-NMR spectral data of 30:654 1H-NMR data of 30:654 2D-NMR spectral data of 30:654 HMBC of 30:656 molecular formula of 30:654 NOESY spectrum of 30:654,656 structure of 30:655 Triptolide 2:404;23:684;29:100,198 activity in APO assay system 29:100 activity in COX assay system 29:100 activity in NFkB assay system 29:100 activity in TNFtx assay system 29:100 against murine L- 1210 leukemia 29:200 as oxygenated diterpene 29:198 biological activity of 29:198 cytotoxicity of 29:200 immunosuppressive activity of 29:200 inflammatory properties of 29:200 9,11-epoxy- 14[3-hydroxy system of 29:200 isolation of 29:198 physical properties of 29:199 Triptolide synthesis 29:200 by Banerjee and Az6car 29:208 by Berchtold et al. 29:200,203 by van Tamelen 29:203 by Yang et al. 29:210
starting material for 29:208 yield of 29:210 Triptolidenol 23:688 Triptolides 23:684 derivatives of 23:684 Triptonide 23:684 Triptonine A 676 Triptonine B 23:676 Triptoquinone A 29:99 activity in iNOS assay system 29:99 Triptoquinones A-G 23:689,690 Tripyranoside 21:432 Triquinane 6:33,34;13:3-25 angular 13:3-25 diterpenes 13:3-52 linear 13:34-56 precapnelladiene from 6:33,34 sesquiterpenes 13:3-52 synthesis of 6:33,34;13:3-52 Triquinane derivatives 7:216 Triquinane terpenes 10:426-428 Claisen rearrangement by 10:426-428 synthesis of 10:426-428 Triquinanes 3:5-7 angular 3:5-7 linear 3:5 synthesis of 3:5-48 Tris (4,5-dichlorophthalimido) trityl bromide (CPTrBr) 14:288 Tris (4,5-dichlorophthalimido)trityl bromide (CPTrBr) 14:288 Trisaccharide 7:31,181 Trisaccharide moiety 27:675 Triscutin A 30:687 13C-NMR spectra of 30:687 ~H-NMR spectra of 30:687 2D NMR spectroscopic data of 30:687 molecular formula of 30:687 structure of 30:687 Triscutin B 30:688 13C-NMR spectra of 30:688 2D NMR experiments of 30:688 FAB-MS of 30:688 ~H-NMR spectrum of 30:688 molecular formula of 30:688 structure of 30:688
831
Trishomononactate 18:253 Trisnorsesquiterpene 21:282 Trisporic acid 7:341,342 from Blakeslea trispora 7:340 Tristamine 25:819,820 2',4',5'-Trisubstituted flavones 5:630 (E)-Trisubstituted olefin 1:406,407 synthesis of 1:406,407 Trisubstituted olefins 4:565 synthesis of 4:565 C30Triterpene 7:317 Triterpene alcohol 25:43,44 Triterpene glycoside 7:267,281;21:314; 24:132;28:596,587,589 antifungal activity of 28:589 cytotoxic activity of 28:589 cytostatic activity of 28:589 hemolytic activity of 28:589 immunomodulatory activity of 28:589 Triterpene quinone methides 7:150-152 biogenesis of 7:150-152 from Cassine balae 7:145,150 from Kokoona zeylanica 7:148152 Triterpene saponin gypenosides 24:144 Triterpene saponins 7:426,427; 21:673;24:131-147 olluscicidal activity of 7:426,427 Triterpenes 5:3,38-41;7:124,131-174; 6:110;15:281,282;18:757-769;17:80; 21:237;23:494;24:241-249,285,799; 25:478;27:702;30:637-663 biological activities of 30:637 bupleuroside III, IV and XIII 25:476 chemistry of 30:637-663 from olive oil 27:702 ginsenoside Rs and Rg 1 25:476 glycyrrhizin 25:476 derivatives 17:118 from ~-amyrin 7:131-145 ofBarringtonia sp. 7:132,133 of Guaiacum officinal 7:139 of Terminalia sp. 7:133-135 physiological function of 30:637 scorzoneroside A,B,C, 25:476 Triterpenic acid glycoside 21:743
Triterpenoid fractions 30:59,60,62 activity in matrigel-implanted angiogenesis assay 30:62 effects on hemoglobin 30:59,60 effects on leukocytes 30:59,60 effects on red cell 30:59,60 isolation of 30:62 Triterpenoid hydrocarbons 24:256-258 Triterpenoid intermediate 4:676 Triterpenoid quinonemethides 23:707 Triterpenoid saponins 27:454 acetylastragaloside 27:456 agroastragaloside I 27:454 agroastragaloside II 27:454 agroastragaloside III 27:456 agroastragaloside IV 27:456 alexandroside I 27:454 asernestioside A 27:456 asernestioside B 27:456 asernestioside C 27:456 askendoside B 27:456 askendoside D 27:456 askenodoside A 27:454 askenodoside C 27:454 askenodoside F 27:454 askenodoside G 27:454 astrachrysoside A 27:456 astragaloside I 27:456 astragaloside II 27:457 astragaloside III 27:457 astragaloside IV 27:457 astragaloside V 27:457 astragaloside VI 27:457 astragaloside VII 27:457 astragaloside VIII 27:457 astragaloside VIII Me ester 27:464 astramembrannin II 27:457 astrasleversianm I 27:457 astrasleverslanm II 27:458 astrasleversxanln III 27:458 astrasleverslanm IV 27:458 astrasleverslanln IX 27:458 astras~eversmnm V 27:458 astrasleversmnm VI 27:458 astrasleverslanm VII 27:458 astrasleverslanln VIII 27:458 astras~eversxanm X 27:458 astrasleverslanm XI 27:458
832
astrasieversianin XII 27:458 astrasieversianin XIII 27:458 astrasieversianin XIV 27:458 astrasieversianin XV 27:458 astravermcin I 27:459 astraverrucln II 27:459 astraverrucm III 27:459 astraverrucln IV 27:459 astraverrucln V 27:459 astraverrucln VI 27:459 astresieversianin XVI 27:459 astrojanoside A 27:464 azukisaponin V 27:464 brachyoside A 27:454 brachyoside B 27:459 brachyoside C 27:454 cephalotoside A 27:454 comploside II 27:464 cycloalpioside 27:463 cycloalpioside A 27:450 cycloalpioside B 27:459 cycloalpioside C 27:459 cycloalpioside D 27:459 cycloaraloside E 27:459 cycloaraloside F 27:459 cyclocanthoside A 27:454 cyclocanthoside B 27:454 cyclocanthoside C 27:454 cyclocanthoside D 27:455 cyclocanthoside E 27:455 cyclocanthoside G 27:455 cyclocarposide 27:459 cyclocephaloside I 27:461 cyclocephaloside II 459 cyclogaleginoside A 27:460 cyclogaleginoside B 27:460 cycloglobiceposide A 27:460 cycloorbicoside A 27:463 cycloorbicoside G 27:463 cyclopycnanthoside 27:455 cyclorbicoside B 27:463 cyclosieversiosdie F 27:460 cyclosieversiosdie G 27:460 cyclosieversioside D 27:460 cyclosieversioside E 27:460 cyclosieversioside H 27:460 dasyanthoside A 27:462 giganteoside D 27:464 huangqiuenin 27:460
huangqiyenin B 27:455 huangqiyenin D 27:460 isostragaloside I 27:460 isostragaloside II 27:460 isostragaloside IV 27:460 macrophyllosaponin D 27:455 macrophyllosaponin C 27:455 macrophyllosaponin B 27:455 macrophyllosaponin A 27:455 monglycoside I 27:455 monglycoside II 27:455 robinioside 27:464 sieberoside I 27:460 sieberoside II 27:461 sophoraflavoside II 27:464 soyasaponin I 27:464 soyasaponin I Me ester 27:464 soyasaponin II Me ester 27:464 soyasaponin III Me ester 27:464 soyasaponin IV 27:464 tomentoside I 27:462 tomentoside II 27:462 trigonoside I 27:461 trigonoside II 27:461 trigonoside III 27:461 trojanoside A 27:461 trojanoside B 27:461 trojanoside C 27:455 trojanoside D 27:455 trojanoside F 27:455 trojanoside H 27:461 trojanosie E 27:455 Triterpenoid saponins 27:454,671 of saikosaponin 27:671 Triterpenoids 5:743-745,750;7:189191 ;9:293-295,297,300,302,307,308; 20:702;22:97 ;23:535,637 ;24:215; 25:43 ;30:55,56,58,59,61,64 antiinflammatory activity of 25:43 antimetastatic effects of 30:58 antitumor activity of 25:43;30:58 biosynthesis of 22:97 effect on angiogenesis 30:61 effect on DNA synthesis 30:61 effect on liver metastasis 30:55 effect on primary solid-tumor growth 30:64
833 effect on secondary metastatic tumor growth 30:64 effect on tumor cell colonies 30:59 effect on tumor growth 30:55 Trithiane 10:244;23:236;25:837 1,2,3-Trithiane 23:235 Trithiane analogue 23:237 1,4,4'-Trithiocello-oligosaccharides 8:348,349 1,4,4'-Trithiocellotrioside 8:348,349 1,2,4-Trithiolanes 25:840,843 15-Tritiated GA3 8:128,129 synthesis of 8:!28,129 Triticum 9:321 Triticum aestivum 18:503,512,520; 19:247 ;27:188,191,193,215,217,218; 29:585,613 allelopathic interaction of 27:214-218 3-dehydroteasteron from 18:500 Triticum BBI 29:600 Triticum vulgare 9:321 Tritofordin F-2 23:672 Triton 11:347 Triton B 6:320-322;12:244 Tritonia crocosmaeflora 23:96 Tritrophic interaction 27:213,214 DIMBoA in 27:213,214 6-O-Trityl protection 6:370 Tritylation 6:282,284,292,293 Trityl-cyanoethylidene condensation 14:219-226 polysaccharides by 14:228 Tritylperchlorate 4:236 as catalyst 4:236 Triumbellatin 20:283 Trixikingolide 13:39,41-46 Triyne alcohol 21:190 Troglatizone 459,488 Trojanoside A 25:193 Trojanoside B 25:194 Trojanoside C 25:198 Trojanoside D 25:198 Trojanoside E 25:198 Trojanoside F 25:198 Trolox 22:324;26:672 Tropacocaine 1:383-385;22:722 synthesis of 1:383-385
Tropane 1:380-382 synthesis of 1:380-382 Tropane alkaloids 17:395;21:56 biosynthesis of 17:395 13C-incorporation 17:416 distribution of 17:401,406 synthesis of 1:378-385;16:442 Tropanyl compounds 25:29 Trophozoite extract 25:334,342,354 Trophozoite stage 25:329 Trophozoites 25:332,333 acetonitrile extract of 25:333 Tropic acid 22:8,718 Tropical diseases 30:329 malaria as 30:329 Tropical ulcers 5:745 Tropilaelaps clareae 28:387 Tropine 1:378;7:191;22:725 3ot-Tropine 22:718 Tropinone 1:378 Tropolones 1:340;23:343 synthesis of 1:340 Tropone 1:549,554-573;10:178;13:624 1,8-addition of lithio tert butyl acetate 1:554 addition to enolates 1:554,555 as diene in [4n + 2re] cycloadditions 1:566,571 cis-hydroazulene from 12:251 diazoketone insertion 1:555 for perhydroazulene synthesis of 1:549-556 iron tricarbonyl complexes 1:572 organometallic derivatives of 1:572,573 photochemical electrocyclic closure 1:549 vinyl sulfide cycloaddition 1:567 Tropone alkaloids 11:204 Trop ono- 1,2-dihydro- 3,6-phena thro line 25:820 Tropoyl-CoA 22:728 Trost cyclization 16:423 ofallylic acetate 16:423 TRPM8 30:193 type of ionotropic receptor 30:193 use in cold-allodynia 30:193
834
TRPVI 30:193 activation of 30:193 receptor desensitisation of 30:193 role in neuropeptide release 30:193 role in nociceptor excitation 30:193 TRPVI (VRI) activation 30:193 by acidosis 30:193 by lipid mediators 30:193 by noxious heat 30:193 TRPVI expression 30:206 effect of capsaicin on 30:206 effect ofpolygodial on 30:206 TRPVI receptor blockade 30:203 by ginsenosides 30:203 Trunculin A 5:354,355 Trunculins A-B 9:18 from Latrunculia brevis 9:20 X-ray analysis of 9:20 Trunkamide A 25:883 fl-Truxilline 22:722 ot-Tmxilline 22:722 Trychostrongylus 26:425 Trypamosoma 18:791,793 Trypanasoma dionisii 18:801-804
Trypanasoma verpertillionis
18:801,804 Trypanocidal activity 26:800 Trypanocidal effect 30:741 of Paraguayan compositae 30:741 Trypanosimatids 18:793
Trypanosoma berghei brucei 26:791,797
Trypanosoma berghei gambiense 26:785-787,791,792,828
Trypanosoma brucei rhodesiense 26:785-787,791,792,825
Trypanosoma burcei 18:448,449;28:148 polysaccharides of 2:3 l0
Trypanosoma congolense 26:785 Trypanosoma conorhini 2:311 Trypanosoma cruzi 18:796-802;23:137, 473 ;24:818,819;26:230,673,787,788, 792,793,797,799,801,802,813,819, 822,828;28:148;29:748
glycosphingolipids of 18:796802 glycocomplexes of 2:302-309 Trypanosoma mega 18:804 glycocomplexes of 2:310,311 polysaccharides of 2:310,311 Trypanosoma spp. 2:301-310;26:786, 779,780,785,786,797,800,803,806808,810,822,824,828,838 glycocomplexes of 2:301-310 polysaccharides of 2:301-310 Trypanosoma vivax 26:785 Trypanosomal 24:799 biological activity 24:799 Trypanosomatides 2:301,314 higher 2:301,314 lower 2:295-301 polysaccharides of 2:295-301 Trypanosomiasis 26:781,785,786,787, 840 Trypanosomicidal activity 26:230 of veraguensin 26:230 of grandisin 26:230 Trypanothione synthesis 26:808 Trypsin 9:500;22:622;25:483; 30:830,831,837 Arg-X cleavage site of 30:837 homologous sequences of 30:831 Lys-X cleavage site of 30:837 Trypsin production 30:204 inhibition by hederagenin monodesmosides 30:204 Tryptamine 9:167,168,177,178; 13:662;15:487;19:100;22:5;26:966 secologanin ondensation with 6:520 Tryptamine-secologanin indole alkaloids 21:129 Tryptanthrin 22:612 Tryptase inhibitor 26:1129 Tryptic digest 9:499,503,504 Tryptic peptide 9:499,503 Tryptofordin 18:772 from Trypterigium wilfordii 18:771 Tryptohypol F 30:647,648 ~3C-NMR spectrum of 30:648 ~H-NMR of 30:648
835 MS spectra of 30:648 NOESY spectrum of 30:648 stereochemistry of 30:648 structure of 30:647 Tryptophan 1:31;11:200;25:823, 885,928;30:369 by 4-(y,y-dimethylallyl) tryptophan synthase 11:200 isoprenylation of 11:200 quinaldic acid from 11:209,210 stereochemical course of 11:200 structure of 30:369 D-Tryptophan 25:885 Tryptophan decarboxylase activity 30:371 in brain neurons 30:371 in non-nervous tissue cells 30:371 Tryptophan derivative 28:369 construction of 28:369 Tryptophan hydroxylase (TPH) activity 30:370 in beta-cells 30:370 in intestinal cells 30:370 in mast cells 30:370 in mononuclear leukocytes 30:370 in pancreatic enterochromaffin cells 30:370 Tsilanimbine 1:38,39 Tsitsikammamine A and B 25:709 2-TST (2-trimethylsilyl thiazole) 11:443,444 (+)-Tsugacetal 26:195 (-)-Tsukushinamine-A 15:520 TTN (thallium nitrate oxidation) 10:631-635,637,638,640,641,644647,653,654,661,662,666,667 Tubastraea aurea 5:359 Tubastrea micrantha 5:360 Tubastrine 5:359-361 Tubatosides 15:191 Tube dilution test 20:712 Tubeimoside I 21:634,637,639,641, 657,731 antitumor activity of 21:733 from Bolbostemma paniculatum 7:143,144
Tubeimoside III 21:732,730,745 Tubeimoside IV 21:735 Tu-bei-Mu (Bolbostemma paniculatum) tubeimoside I from 7:143,144 Tubercidin 25:712,713 Tuberculatin 26:194,263 Tuberculosis 12:37 rifampicin for 12:37 Tuberostan 4:382,383 from (+)-isomedicarpin 4:382,383 Tuberostemonine 21:769 Tuberous sclerosis 30:374 autistic features in 30:374 Tubifolidine 1:41,42,45,46,51,52,67 synthesis of 1:41,42,45, 46,51,52,67 20-epi-Tubifolidine 1:67 synthesis of 1:67 Tubifoline 1:41,45,46,51,52 synthesis of 1:41,45,46,51,52 Tubipora musica 24:119 Tubocurarine 13:631 ;21:52,102 from Chondodendrum tomentosum 13:631 d-Tubocurarine 18:698;22:30 et-D-Tubocurarine 22:17 Tubotaiwinal 1:40 (+)-Tubotaiwine 5:125 Tubotaiwine 1:33,40;6:503;9:190,191 biogenesis of 6:503 synthesis of 1:41,49,50 Tubotaiwine-N4-oxide 5:125 Tubulanus punctatus 18:725 Tubules 22:32 Tubulin 11:5;22:32;26:753,828 fl-Tubulin 22:461 (+)-Tubulosine 18:330 Tubulosine 9:401 ;13:92;21:97;22:29 X-ray crystal analysis of 9:401 Tulipa gesneriana 19:247 Tulipinolide 7:231 Tulirinol 27:572 Tullidinol 22:574,575,585,588,590 Tullidinol B1,B2 22:574,575,577 Tullidora 22:558 Tumor 28:532;30:61 effect of lipid A on 28:532
836
in host response to LPS 28:531 in LLC-bearing mice 30:61 Tumor cell colonies 30:59 role of triterpenoid fractions 30:59 Tumor growth 28:581 ;30:56,57,60, 64,70 effects of 2,3,5,4'-tetrahydroxystilbene-2-O-D-glucoside on 28:581 efect of fucoidan on 30:56 effect of triterpenoid fractions on 30:60 in LLC-bearing mice 28:581 in sarcoma 30:56 in spleen 30:64 inhibition by carp oil 30:64 inhibition by oleic acid 30:64 prevention of 30:60 Tumor metastasis 25:440,454;30:55 role of natural products in 30:55 Tumor necrosis factor-a (TNF-ot) 5:385,387;12:396;23:142,475; 25:459,460,461,477,598;27:851; 28:219 as tumor promoter 28:219 staurosporine effect on 12:396 Tumor prevention 30:64 use of carp oil 30:64 Tumor production inhibition 30:695 Tumor promoter 2:286,287;30:592 TPA as 30:592 Tumor specificity 25:442 Tumor therapy 6:261 polyene macrolides in 6:261 Tumorigenesis 30:316 initiation of 30:316 promotion of 30:316 Tumor-inhibitory activity 23:126; 24:202-206 of yeast glucan 23:126 Tumor-promoting 12:233-274 diterpenes 12:233-274 synthesis of 12:233-274 phorbol ester 25:190 Tumor-promotion agents 30:592 diterpene esters from 30:592 12-O-tetradecanoylphorbol 13acetate (TPA) as 30:592
Tumour-inhibiting activity 17:341; 20:408 Tumour-promoter activity 15:462 of pendolmycin 15:462 Tuna oil 28:566 anti-tumor activity of 28:566 Tunaxanthin 7:320 Tunefulin 27:585 Tunicaminyl uracil 10:572 asymmetric induction of 10:572 Tunicamycins 1:398,417-42;11:430, 446-449 dolichyl-pp-Glc NAc inhibitor of 10:569 from Streptomyces lysosuperificus 10:568 total synthesis of 10:570-572 synthesis of 1:417-421 ;11:446449 Tunicata 21:3 Tunicates (Ascidians) 19:549;21:321 ; 28:621 ascidiacyclamide from 28:622 bistratamides from 28:622 lissoclinamides from 28:622 patellamides from 28:622 Tunichlorin 10:245,246 Tunichrome A 10:241,242 Tunichrome An-1 23:242 Tunichrome B-1 23:242 Tunichromes 23:241,243 Turbatrix aceti 26:481 Turbo connutus 7:270 mixed glucosidase from 7:270 Turdoides somerville 5:837 hemoglobin components of 5:837 c~-Turmerone 23:834 [3-Turmerone 23:834 (+)-ar-Turmerone 26:457 (-)-ar-Turmerone 8:39 [LTurmerone 8:51,55,56 from Curcuma longa 8:52 (-)-[3-Turmerone 8:52,55,56 synthesis of 8:52,55,56 Turnefocidine 1:228,246;3:54 synthesis of 1:228,246 Turpentine 25:151
837
Turus migratorius 5:836 hemoglobin components of 5:836 Tussilagin 1:230,231 synthesis of 1:230,231 Tutufa lissostoma 18:724 Twelve-carbon sugars 4:190 synthesis of 4:190 Two-spotted spidermite 12:397 Two-stage coupling process (tandem process) 12:35-62 Two-stage mouse skin model 30:591 cancer chemopreventive activity in 30:591 TXB~ production 25:593 Tylenchulus semipenetrans 26:456,469 Tylocrepine 21:97 Tylohirsutidine 12:301 Tylohirsutine 12:301 Tylonolide 10:170;11:152,158-163,164 synthesis of 11:158-163 Tylopherine 21:97 Tylophora hirsuta 12:300 phenanthroindolizidine alkaloids from 12:300 Tylophora sp. 1:360 Tylophorine 1:360-362;4:604,605 synthesis of 1:360,362;4:604,605 Tylosin 5:609,612,10:153,170 Type-111 secretion system 25:394,398 Typha latifolia 19:247;26:358,361 Typhasterol 16:324;18:500,512,520 synthesis of 19:258 Typhlodromus urticae 28:430 asimicin from 28:430 desacetyluvaricin from 28:430 squamocin from 28:430 Tyr-(Me)2-D-Phe-Gly-Val-Val-NH2 30:812,813 activity in GPI assay 30:812 binding bioactivity of 30:813 functional bioactivity of 30:813 Tyr-(Me)2-D-Phe-NH2 30:812,813 activity in GPI assay 30:812 binding bioactivity of 30:813 functional bioactivity of 30:813 Tyr(Me)z-Phe-NH2 30:813 binding bioactivity of 30:813 functional bioactivity of 30:813
Tyr-(Me)2-Phe-NHCH3 30:812 energy map of 30:812 ~251-Tyr2, Ala 16-systemin 25:373 Tyramine 6:525,529;22:14,630,631 Tyr-D-Ala-Phe-[[3-D-Glc(OAc)4]TyrPro-Ser-NH2 30:815 receptor binding properties of 30:815 Tyr-D-Ala-Phe-Asp-Val-Val-Gly-NH2 (deltorphin C) 30:815 receptor binding properties of 30:815 Tyr-D-Ala-Phe-Asp-Val-Val-Thr([3-DGlc)-Gly-NHzTyr-D-Ala-Phe-Thr[ [3D-Glc(OAc)4]-Val-Val-Gly-NH2 30:815 receptor binding properties of 30:815 Tyr-D-Ala-Phe-Asp-Val-Val-Thr [[3-DGlc(OAc)4]-Gly-NH2 30:815 receptor binding properties of 30:815 Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2 (deltorphin C) 30:815 receptor binding properties of 30:815 Tyr-D-Ala-Phe-Gly-Tyr-Pro-Thr([3-DGlc)-Gly-NH2 30:815 receptor binding properties of 30:815 Tyr-D-Ala-Phe-Gly-Tyr-Pro-Thr[[3-DGlc(OAc)4]-Gly-NH2 30:815 receptor binding properties of 30:815 Tyr-D-Ala-Phe-Thr([3-D-Glc)-Tyr-Proser-NH2 30:815 receptor binding propertxes of 30:815 Tyr-D-Ala-Phe-Thr([3-D-Glc)-Val-ValGly-NH2 30:815 receptor binding properties of 30:815 d-Tyr(Me)z-Phe-G-V-V-NH2 30:813 binding bioactivity of 30:813 functional bioactivity of 30:813 d-Tyr(Me)z-Phe-NH2 30:813 binding bioactivity of 30:813 functional bioactivity of 30:813
838
Tyrindoxyl sulfate 28:652 as Tyrian purple dye 28:652 Tyromyces sambuceus 21:197 Tyrophagus putrescentiae 28:421 Tyrosin nitrosylation 26:926 Tyrosinase activity assay 21:587 Tyrosinase inhibitory activity 21:587 (-)-Tyrosine 16:595 photooxygenation of 16:595 Tyrosine 16:608 mechanisms of 16:608 oxygenation of 16:595 [lac(u)]Tyrosine 21:322 L-Tyrosine 21:414 Tyrosine 21:738;23:234;27:751 iodination of 27:751 Tyrosine ammonia-lyase (TAL) 5:467,468;25:669 Tyrosine kinase 12:394 Tyrosine kinase activity 15:441 ;21:135; 27:854 Tyrosine kinase inhibition 21:135,152 Tyrosine kinase inhibitors 15:447449;25:691,720 biological activity of 15:447-449 Tyrosine kinase-mediated signaling 25:545 Tyrosine kinase receptor 27:824, 825,827 Tyrosine kinases 25:597 Tyrosine phosphatases (PTPases) 25:519 Tyrosine phosphorylated STAT dimer (P-STAT) 25:522,548 Tyrosine phosphorylation 26:753 Tyrosine-specific kinase 19:178 inhibitor of 19:178 Tyrosol 16:582;22:79;26:333 photosensitized oxygenation of 16:582 Tyr-Tic-NH2 30:809 activity in functional bioassay 30:809 Tyr-Tic-Phe-NH2 30:806 as 8 selective antagonist 30:806 U2 66 myeloma cell 25:273
Uang synthesis 12:26,27 of avermectin oxahydrindene subunit 12:26,27 of (7-hydroxystaurospermines) 12:26,27 Ubiquinol- 10 26:1006 Ubiquinone 22:253 Ubiquinone oxydoreductase 26:924 UC 11136 21:396 Uca pugilator 19:628 UCF 1-A,B and C 21:404 Uchotensimine 1:201,202 synthesis of 1:201,202 UCN-01-UCN-02 12:386 antitumor activity of 12:395 from Streptomyces sp. N-126 12:366,368 protein kinase inhibitor of 12:386 Udotea flabellum 16:312 Udoteatrial 16:312-316 antimicrobial activity of 16:312,315-316 from Udoteaflabellum 16:312 synthesis of 16:312-316 UDP glucose coniferyl alcohol glucosyltransferase 5:471 UDP-galactosamine (UDP-GaIN) 25:461 UDP-GlcNAc 1:417 distribution of metabolism 1:417 U-endo-fl-l,4 galactanase 25:436 Ueno method 10:322,323 reduction by 10:322,323 U-exo-fl-galactosidase 25:436 Ugi reaction 12:114-138;26:1221 Uhdoside 26:321,322 3',4-O-Uimethylcedrusin 26:202,269 Ulapualide A and B 17:16 Ulapualides A 19:609 antifungal activity of 19:609 Ulbelliferae 7:115,119,120,415 Ulbelliferone 7:224 Uleine 1:56-58 synthesis of 1:56-58 Ulicyclamide 5:419,420;10:242; 25:880,882 cytotoxic activity of 5:419 Ulicyclamide group 4:83,84
839
Ulithiacyclamide 5:419;10:242;25:879 cytotoxic activity of 4:101,102; 5:419 synthesis of 4:89,90,99,100 Ulithiacyclamide B 25:879 Ulithiacyclamide E 25:879 Ulithiacyclamide G 25:879 Ullmann biaryl synthesis 20:294-301 Ullmann diarylether synthesis 20:307310 Ullmann macrocyclization 20:308 Ulmann reaction 10:629-631,641,644, 646-653,655,661,667;13:353,354, 364 ;20:294,296,297 ;24:779,780 intramolecular 10:640 Ulmus thomasii 17:338 Ulosonic acid 30:422,432,433,438 acylation reactions for 30:438 chemical synthesis of 30:432 strategies towards 30:438 synthesis of 30:422 treatment of enolpyruvate 30:432 Ulosonic acid synthesis 30:451-458 alternative approach to 30:452 from glycals 30:453-458 from pyranoses 30:451-453 2-Ulosonic ester halides 30:467 glycosylation reactions of 30:467 Ultracentrifugation 20:497 Ultra-turrax-type homogenizers 21:503 Ultra-violet diode array detection 21:543 Ultraviolet spectrophotometry (UV) 5:621,622 of flavonoids 5:621,622 of flavonols 5:622 of 3-methoxyflavones 5:622 2'-substituted flavonoids 5:622 of 2',4',5'-trisubstituted flavonol3-methyl ether 5:630 Ulva lactuca 7:338;30:408 (6S,6'S)-e,a-carotene from 7:338 anti-influenza activity of 30:408 Ulva perfusa 21:305 Ulva sp. 25:725 (+)-Umbelactone 16:694 synthesis of 16:694
Umbelliferae 23:512 Umbelliferae genera 27:361,686 Umbelliferone 4:385,386;9:114;20:497; 23:356 from Pleisopermium alatum 20:497 in 6-(3,3-dimethylallyl)-7hydroxycoumarin synthesis 4:385,386,20:497 in osthenol synthesis 4:385,386 in 7-O-prenylcoumarin synthesis 4:385,386 in xanthone synthesis 385,386 with prenyl bromide 4:385,386 Umbellifolide 7:215,237 from Artemisia umbellijbrmis 7:215 Umbelliprenin epoxide 1:661 cyclization of 1:661 Umbilicaria angulata 5:311 Umbilicaria caroliniana 5:311 Umbilicaria polyphylla 5:311 Umbraculum mediterraneum 25:831; 28:650 Umbrosianin 15:119 13C-NMR of 15:133 from Rabdosia umbrosa 15:175 lH-NMR of 15:126 Umbrosin A 15:175 from Rabdosia umbrosa 15:175 from Rabdosia umbrosa var. hakusanensis 15:175 Umezakia 26:352 Umpolung 10:160,167 Umpolung-Michael-Addition 8:46 Uncaria genus 17:122 Uncaria guaianensis 17:116,124; 22:363 Uncaria rhyncophylla 22:534 for convulsions in children 22:534 Uncaria tomentose 22:362 Uncarine C,D,E and F 25:25 Uncatalyzed thermal cycloaddition reaction 12:425 (Z)-Undec-8-ene-2,5-done 19:161 Undecane 21:600 N-Undecane 6:453,454 as alarm pheromone 6:453,454
840
1,3Z,5Z,8Z-Undecatraene 21:306 Undecatrione 6:450 reductive amination of 6:450 (Z)-5-Undecen-2-one 19:123 6-Undecyl catechol 2:280 3-Undecyl phenol 2:280,281 6-Undecyl salicylic acid 2:280,281 Undecylenic acid 8:224 Undecylprodigiosin 8:272 Unedoside 7:440 Ungeremine 26:610,616,617,618 Ungernia minor 26:616 Unipolar depression 30:369 effect of circadian activity on 30:369 Unnatural enantiomer 27:346 Unnatural sialic acid analogues 30:428 synthesis of 30:428 Unnatural ulosonic acid analogues 30:460 synthesis of 30:460 Unonpsine 26:827 Unprotected quinone 11:123 naphthacenequinone from 11:123 2,3-Unsaturated 1-thioglycosides 8:343 synthesis of 8:343 ( 11)-Unsaturated 5~x-8cxperoxystrerols 5:406 c~,[3-Unsaturated acetal 14:502 cyclic enones with 14:502 from dialkyl tartarates 14:489-491 photocycloaddition of 14:502 Simmons-Smith reaction of 14:489-491 Unsaturated acetals 14:490 cyclopropanation of 14:490 from (-)-(2S,3S)-1,4dibenzyloxy-2,3-butanediol 14:490 2,3-Unsaturated allyl glycoside 10:420 preparation of 10:420 A asymmetric aldol reaction of 12:162 4-unsubstituted [3-1actam from 12:162
2,3-Unsaturated allyl glycoside 10:420 preparation of 10:420 Unsaturated amides 24:683-738 Unsaturated anacardic acids 30:143 synthesis of 30:143 AS'7-Unsaturated brassinosteroids 18:515-520 A'~,[3-Unsaturated butenolide ring 25:276 c~,~-Unsaturated butyrolactones 11:453 Unsaturated C-18 fatty acids 1:528-533 Unsaturated carbapyranoses 29:475 as enzyme inhibitors 29:475 as herbicidal 29:475 biological properties of 29:475 preparation of 29:475 rancinamycins as 29:476 synthesis by Arjona 29:477 unnatural antipode of 29:475 Unsaturated carbapyranoses synthesis 29:475 by Arjona 29:475 c~,[3-Unsaturated carbonyl compounds 4:46 oxidation of 4:46 c~,[3-Unsaturated carboxyl system 27:349 2,3-Unsaturated C-glycofuranosyl 10:341 by Claisen reaction 10:341 from glycal 10:341 Unsaturated C-glycopyranoside 10:345 frompyranoid glycals 10:345 synthesis of 10:345 2,3-Unsaturated C-glycoside 10:346, 349,350 from Claisen rearrangement 10:338 from lithioglycal 10:312 from peracetylated glycals 10:350 regioselectivity of 10:350 stereoselectivity of 10:350 synthesis of 10:350 1,2-Unsaturated C-glycoside 10:349 Unsaturated C-glycoside 10:354,355 alkylation with dibenzylidene acetal bis (diphenylphosphino)
841
ethane 10:343 alkylation with trifluoroacetate ester 10:343 by palladium (0)- 10:354,355 [3-dicarbonyl C-glycoside 10:348 from glycosyl fluoride 10:368 from peracetylated glycols 10:343 2,3-Unsaturated C-nucleoside 10:341, 342 by reaction of furanose-glycals 10:341 synthesis of 10:341 with pyrimidine-mercury/ palladium acetate 10:341 Unsaturated epoxy hydroxy acids 27:81,82 by nonenzymic induced oxidation of linoleic acid 27:81 (E)-c~,[3-Unsaturated ester 13:89 5,6-Unsaturated hexopyranosyltheophylline synthesis of 4:237 ct,13-Unsaturated imide 12:162asymmetric aldol reaction of 12:162 4-unsubstituted [3-1actam from 12:162 c~,[3-Unsaturated ketone 12:46 XH-NMR spectrum of 12:46 NOE experiments of 12:46 in Luche-type reduction 4:130 reaction with silyl enol ethers 3:126,127,129 reduction of 4:382,383 stereochemistry of 12:46 synthesis of 6:339,340 with 2-methyl-6-vinylpyridine 14:438 Unsaturated ketonucleosides 4:248,253 synthesis of 4:248,253 tumor inhibition by 4:253 A-8,9-Unsaturated lactol 4:420,421 in endoperoxide rearrangement 4:420,421 Z-[3,7-Unsaturated macrolide 8:232 synthesis of 8:232
(x,[3-Unsaturated methoxymethylester 10:412 fragmentation-recombination of 10:412 (x,13-Unsaturated nitroolefins 14:636638 2,3-Unsaturated nucleosides 4:223 1,3-intramolecular shift of 4:223 2-Unsaturated nucleosides 4:225 Unsaturated nucleosides 4:235-237 synthesis of 4:235-237 Unsaturated O-glycosides 10:354,355 c~,[3-Unsaturated orthoesters 3:146-149 Michael acceptors 3:146-149 A4-Unsaturated oxepene 10:221 2,3-Unsaturated pentose 10:425 from D-xylal 10:425 ALUnsaturated sterols 25:56 schottenol 25:56 spinasterol 25:56 2,3-Unsaturated c~-C-glycopyranosylarenes 10:345 Unstable D-mannose derivative 30:462 Unsubstituted 2-oxazolidone derivative 12:164,166 low [3-selectivity of 12:166 with 4-acetoxy ~-lactam 12:164,166 4-Unsubstituted [3-1actam 12:162 4-acetoxy [3-1actam from 12:162 by asymmetric aldol reaction 12:162 by asymmetric hydrogenation 12:162 of [3-keto amide 12:162 of (x,[3-unsaturated imide 12:162 oxidation of 12:162 with peracids 12:162 Unsymmetrical chiral biaryls 20:410 Unsymmetrical onoceranoid triterpene 1:543 synthesis of 1:543 Unsymmetrical pyrazines 18:887-892 Uoamine B 28:644 3-thiomethylacrylate ester group of 28"644 Uperolein 27:754
842
(+)-Upial 6:65,66 from Dysideafragilis 6:65 synthesis of 6:65,66 14-epi-Upial 6:67,68 by Knoevenagel condensation 6:67,68 by vinylation 6:67,68 by Wittig reaction 6:68 synthesis of 6:67,68 U-plasminogen activator (u-PA) 30:844 Uptake blocker 21:84 Uranium (IV) hexafluoroacetylacetonate 8:466,467 Urapualide A 5:396,397 Urapualide B 5:396 Urdamycin A 11:134 antifungal activity of 11:134 antitumor activity of 11:134 from Streptomyces fradie 11:134 Urdamycin B 11:134 urdamycinone B from 11:134 Urdamycin E 5:596;11:134 Urdamycin G 11:134 (+)-Urdamycinone B 11:142-144 from L-rhamnal 11:142-144 from urdamycin B 11:134 synthesis of 11:134,135,142-144 Urdamycins 5:596;11:134 Uredinales 9:203 Urediniomycetes 9:202,203 Uredospores 9:220-222 bioassay of 9:220-222 Ureterolithiasis-drug-therapy 27:382 Urethanase 25:719 Urethane 14:566,567 cyclization of 14:566,567 Uric acid 25:930 Uridine 23:97 Uridine 5'-triphosphate 27:820 Uridine diphosphate Nacetylglucosamine 1:399 Uridine diphosphate-galactose (UDPgal) 10:468 synthesis of 10:468 Urinary tract infections 26:50 Herniaria hirsuta in 26:50 Urine retention 30:194 as opioid's side effect 30:194
Urogens I-IV 9:591,592,596, 598,600,602-605,607 Uromyces phaseoli 9:220 Uronate 14:180 Uronic acid 7:156;25:435,486; 26:1154,1156 Uronide elicitors 25:488 Uronolactones 14:192 Uroporphyrinogens 9:607 Urospora penicilliformis 26:1137 Uroterpenol 29:83 activity in mare-2 assay system 29:83 activity in RAS assay system 29:83 Ursane 22:94;23:692;25:53,57,59 Ursane triterpene 29:585 effect on CHY 29:585 Ursolic acid 2:129;7:189;9:293,295, 402;21:671 ;23:535,701,707;25:59, 60,61,66,543 ;28:18,40;29:588; 30:720 effects on HIV- 1 protease 29:575 effects on LELA 29:588 from Eremophila caerulea 15:281 inhibition of HIV- 1 protease dimerization by 28:18 structure of 30:720 Ursonic acid 23:535 Urtica dioica L. 29:697 Urushiols 9:318,325,328, 329,331,334,338,352-354,356,358360;364;30:146 from anacardic acid 9:341 ozonisation of 30:146 Usambarensine 21:56;26:1062 anticancer activity of 26:1060 Usambarine 26:1063 (+)-Ushinsunine 16:511 Usnea rubescens 5:310 Usnea sp. 5:311,313 Usnic acid 9:387 Ustilaginales 9:203 Ustilago maydis 22:263;25:389 Ustilago sp. 9:203 Ustillaginomycetes 9:202,203 Utenone A 23:208
843 Uterine tumor 30:27 effect of pironetin derivatives in 30:27 Utilin 9:96 X-ray crystal structure of 9:95 Usambarine 26:1062 anticancer activity of 26:1060 UV absorptions 30:581-583 of (+)-N-formylovigerine 30:582 of 7-formyldehydroovigerine 30:581 of ernamymphine 30:582 ofherveline A 30:583 UV irradiation 30:486,489 ofprovitamins 30:486 of provitamin D derivatives 30:489 UV spectroscopy 9:164,173 of indole alkaloids 9:164,173 UV spectrum 30:570,584,587 of (-)-6'-hydroxyyatein 30:587 of (-)-hernone 30:587 of demethylsonodione 30:570 of ovihernangerine 30:584 Uvaol 9:293,20:6,17;22:122,125; 29:588 ;30:721 ;29:575 effects on HIV- 1 protease 29:575 effects on LELA 29:588 structure of 30:721 Uvaria accuminata 17:251 uvaricin from 18:193 Uvaria narum 18:221 isodencetyl uvaricin from 18:221 Uvaria pauciovulata 28:422 Uvaricin 17:271 from Uvaria acuminata 18:193 UV-DAD 21:543,544,545,550,554
Vaccaria segetalis 26:50 imunomodulatory effect of 20:50 Vaccaroside D 26:29,30 enzymatic hydrolysis of 26:30 COSY of 26:29 HMBC/HSQC correlations of 26:29 HOHAHA spectrum of 26:29
phase-sensitive NOESY spectrum of 26:29 Vaccaroside E 26:30 Vaccaroside F 26:29,30 1H and 13C spectra of 26:30 acid induced rearrangement of 26:31 alkaline and enzymatic hydrolysis of 26:30 FAB-MS of 26:30 HMBC/HSQC correlations of 26:29 IR spectrum of 26:30 Vaccination 30:408 for respiratory infection 30:408 Vaccinia 27:873 Vaccinium angustifolium 23:782 Vaccinium corymbosum 29:585 Vachanic acid (illicic acid) 7:212,236 Vadrikine 9:193 Vaginatin 5:724,725,728 Valanimycin 26:443 (+)-Valencene 13:300 (+)-nooktatone from 13:300 Valencene 25:125,128,170,171 Valepotriates 13:660 from Valeriana officinalis 13:660 n-Valeraldehyde 19:484 Valerian 13:660 Valeriana hardwickii 22:534 for epilepsy 22:534 for hysteria 22:534 for hysteroepilepsy 22:534 Valerianajatamansi 22:534 Valeriana leshchenaultii 22:534 Valeriana officinalis L. 6:524;22:534; 26:270 for epilepsy 22:534 for hysteria 22:534 for hysteroepilepsy 22:534 (+)-l-hydroxypinoresinol from 26:270 monoterpene alkaloids from 6:524 (+)-pinoresinol-[3-D-glucoside from 26:270 (+)-pinoresinol from 26:270 (-)-prinsepiol from 26:270
844
Valeriana wallichii 22:534 for epilepsy 22:534 for hysteria 22:534 Valerinaol 21:583 y-Valerolactone 18:198 Validamine 10:518;13:189,195,225; 29:481 effects on galactosidases 29:481 effects on mannosidases 29:481 effects on N-linked oligosaccharide-processing mannosidases 29:481 from Streptomyces hygroscipieus subsp, limoneus 10:518 porcine intestinal disaccharidases 10:518 yeast ot-glucosidase inhibitor of 10:518 synthesis of 13:190 Validamine synthesis 29:481 by Kameda 29:481 by Yoshikawa 29:481 Validamycin 7:47 as a-glucosidase inhibitors 7:47 Validamycins A-H 13:223,235 synthesis of 13:228-232 Validamycin B 13:195,223,224 synthesis of 13:231,232 Validamycin G 13:195,223,224 Validamycin A 13:228-231 from Streptomyces species 13:189 synthesis of 13:228-231 Validone 13:195 Validoxylamin A 7:46;13:195,223-228 Validoxylamines B,G 13:224-228 Valienamine 13:189,195,198;29:486 as neuraminidase inhibitors 29:487 as c~-amylase inhibitor 29:486 c~-glucosidase inhibitors of 7:46;10:518 by [2,3]-sigmatropic shift 10:523 from Streptomyces hygroscopicus subsp, limoneus 10:518 from L-quebrachitol 13:199 porcine intestinal disaccharidases 10:518
stereoselective synthesis of 10:521,522 synthesis of 10:507;13:199 valiolamine from 13:201 yeast et-glucosidase inhibitor of 10:518 Valienamines 29:486 acarbose as 29:486 synthesis by Kim's group 29:487 carbapyranuronic acid as 29:487 guanidine substituted cyclohexane derivatives as 29:487 Valienamines synthesis 29:486 by Bianco 29:487 by Park and Danishefsky 29:486 (3S,4R)- [4-2H1, 4-3Hl]Valine 11:211 Valine 11:418,419 synthesis of 11:418,419 L-[U-C13]Valine 15:347 Valine 22:33,381 l-Valinol 10:406 8-Valinol 10:406 (S)-Valinol 20:436 Valinomycin 10:256 Valinuoctins 24:459 FPTase inhibition by 24:459 Valiolamines 13:189,195;29:484 as glucosidase inhibitor 29:484 biological potential of 29:484 from valienamine 13:201 in clinical trials 29:484 in treatment of diabetes 29:484 N-[2-hydroxy- 1-hydroxymethyl) ethyl]-derivative of 29:484 porcine intestinal disaccharides 10:518 synthesis of 13:201 yeast ot-glucosidase inhibitor of 10:518 Valiolamine synthesis 29:485 by Ikegami 29:485 by Shing and Wang 29:485 starting from tetra-O-benzylgluconolactone 29:485 Vallapin 7:185,187 Vallartanone A 17:26 Vallartanone B 17:26 (+)-Vallesamidine 18:318
845
19,20-Z-Vallesamine 5:137,138 ~3C-NMR spectrum of 5:137,138 ~H-NMR spectrum of 5:137,138 COSY-45 spectrum of 5:138 IR spectrum of 5:137 mass spectrum of 5:137 UV spectrum of 5:137 Vallesamine 5:87,88,123,135;6:504; 9:171-173 Vallesiachotaman-type alkaloids 5:71, 84 isovallesiachotamine 5:85 vallesiachotamine 5:85 Vallesiachotamine 1:89,90;2:375;5:127 synthetic derivatives 1:91-94 Vallesiachotamine lactones 1:95-98 Vallinoids 30:200,201 N-alkylhomovanillamides as 30:201 N-vanillyl-N-benzylureas as 30:201 N-vanilly-N-(3-acyloxy-2benzylpropyl)-thioureas as 30:201 resinifeonoids as 30:201 Valoneanic acid 20:272 Valoneoyl group 23:400,403,415 in olegomers 23:403 Valproic acid 22:507;23:572 enantiomeric analogs of 23:572 Valsa ceratosperma 15:385 5-methylmellein from 15:385 Valtrate 7:441 Van Deemter curve 9:458 Van der Waals effects 17:556,558 Van Tamelen 29:203 triptolide synthesis by 29:203 Vanacoside 22:609 Vanacosides A 22:613 Vanacosides B 22:613 Vanadium (V) compounds 20:305 Vanadium haloperoxidase 25:758 Vanaliculatol 26:553 Vancomycenic acid 20:283 Vancomycin 10:629,630,657-660; 25:791 ;25:791 ;26:366;20:283,296 synthesis of 10:661-669
Vancoresmycin 28:150 activity against gram-positive bacteria 28:150 Vancouveria hexandra 29:788 Van de Walle (iridoids) 8:139 Van de Walle approach 6:16 in [3-dictyopterol synthesis 6:16 in dictyopterone synthesis 6:16 Vandrikidine 9:193 Vanilla planifolia 25:126 Vanillic acid 23:750;25:90,671,924,925 p-Vanilliccinnamic acid 25:923 Vanillin 25:126 o-Vanillin 4:21 allylation of 4:21 Vanillin 7:88,457;8:309;9:457;13:337, 338,362,363 Vanillin assay 21:502,519-522 Vanilline phosphoric acid 22:129 Vanilloid receptor agonist 30:202 olvanil as 30:202 capsaicin as 30:201,202 structure of 30:202 Vanillomopis arborea 29:89 Vanilloyl imidazole 25:8372Vanilloylglycine 25:90,923 Vantanea peruviana 29:708 Varacin 23:236,237 thiomethyl derivative of 23:237 Varacin A 25:834 Varacin B 25:834,835 Varacin C 25:835 Varacin-lissoclinotoxin 25:833 Varamine A,B 10:243,244 Varamines 25:821;25:893 Variabilin 25:717,718 Varicella-Zoster virus 30:394 cause of 30:394 Varicinal A 23:56 Varroajacobsoni 28:387 honey bees tolerant to 28:387 toxicity of 28:387 Varroa mites 28:383,384,392 as honey bee parasites 28:384 biological activity of 28:392 Vascular dilatation activity 23:139 Vascular physiological action 30:55,69 of natural products 30:55,69
846 Vasicine 5:751,752 from vicinal tricarbonyl 8:274 Vasicinol 5:752 Vasicinone 5:752 Vasoconstriction 21:91 Vasodilating activity 21:379 Vasodilator 23:358 scoparone as 23:358 Vasodilator activity 23:358 of scoparone 23:358 Vasodilator effect 25:595 of acetylcholine 25:595 Vasodilatory activity 30:275 ofSatujera obovata 30:275 Vasopressin 22:25;27:800 Vasoprotective agent 22:443 Vasoprotective effects 28:302 of green tea 28:302 Vasorelaxant chalcone 25:540 Vatdiospyroidol 23:533,538,546;26:563 structure of 23:546 (+)-Vateamine-2 ' [3-N-oxide 30:567, 590,595 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 as platelet aggregation inhibitor 30:594 cytotoxic effect of 30:589 Vateriopsis 23:532 Vatica affinis 23:538,547 Vatica diospyroides 23:533,538,547 Vaticaffinol 23:533,538,544 13C-NMR data of 23:544 ~H-NMR data of 23:544 mass fragmentation of 23:544 Vaticaffinol 26:553,562 Vaticaphenol A 23:533,538;26:563 Vatienamine 22:177 Vaucheriaxanthin 6:135,136 Veatchine 3:435;26:868 synthesis of 3:435 Vedejs reagent 11:80,81 Vegetable phenolics 23:752 in artichoke 23:752 in asparagus 23:754 in broccoli 23:756 in cabbage 23:756
in carrot 23:754 in cauliflower 23:756 in celery 23:755 in chicory 23: 758 in chive 23:758 in crucifferae 23:756 m cucumber 23:757 in cucurbitaceae 23:757 in eggplant 23:757 in endive 23:758 m garlic 23:758 in leeks 23:758 m lettuce 23:758 an melon 23:757 in onion 23:761 an pepper 23:763 in pumpkin 23:757 In spinach 23:764 m squash 23:757 in sweet 23:763 In tomato 23:765 Veinotonic activities 21:633 Velbanamine 14:810,862,863;26:1047, 1048 from 1-glutamic acid 14:866-867 synthesis of 14:810,865-869 via thio-Claisen rearrangement 14:865 14,20R-Velbanamine 5:124 Vellosimine 13:386,403 Vellozia candida 20:474 rosane diterpenoids of 20:474 Velocitermes velox 14:451,452;27:385 from Peru 27:385 (+)-intermedeol from 14:451,452 Velutin 7:228 Velutinal 26:461 Venetian lagoon 28:702 Venom gland alkaloids 6:422-465 Venoterpine 6:527 Venturia inequalis 21:217;22:459 Venustatriol 5:361-363 biogenesis of 5:363 Vepridimerine A 2:122-124 biosynthesis of 2:122-124 structure of 2:121 synthetic approaches to 2:125-128 total synthesis of 2:127,128
847
Vepridimerine B 2:122-124 biosynthesis of 2:122,123 structure of 2:121 synthetic approaches to 2:125-128 total synthesis of 2:127,128 Vepridimerine C 2:122-124 biosynthesis of 2:123,124 structure of 2:122 synthetic approaches to 2:125-128 total synthesis of 2:127,128 Vepridimerine E 2:128 Vepridimerines 2:121-128 Vepris lousii 2:121 Veprisimmerines A, C and E 2:123 biosynthesis of 2:123 Veprisine 2:127,128 dimerization of 2:121,122 thermolysis of 2:127,128 Veraguensin 26:230,231,799 trypanosomicidal activity of 26:230 Veramines 25:821 Verapamil 25:534,673;26:1063 as Ca2+-channel blocker 25:487 Veratraldehyde 6:334;26:1013 (3,4-dimethoxyphenyl) methyl ketone from 6:334 Veratrate 5:725,726 of epoxyj aeschkeanodiol 5:725,726 of lancerotol 5:725,726 Veratridine 21:73;22:19,24,35;25:534 Veratrine 21:73,80 Veratrum 23:563-589 embryonic development of 23:563-589 Veratrum album 23:569 Veratrum alkaloids 7:16,20-22 Veratrum califormicum 7:16;23:564, 568,569 steroidal alkaloids from 7:16 Veratrum nigrum L. 22:534 in convulsions 22:534 Veratrum sp. 21:97 Veratryl alcohol 26:1013 Verbascoside 22:77;25:468;26:327,328
Verbasum thapsus L. 22:535 in infantile convulsions 22:535 Verbenaceae 25:249 Verbenalin 7:349,476,490 Verbenol 25:152 cis-D-Verbenol 25:152 (+)-Verbenone 15:227;16:242 from Eremophila dempsteri 15:227 Verbenone 25:152,153 Verbesina 26:437 Verbesina rupestris 16:131 Vergatic acid 20:702 from Salvia limbata 20:702 Verlotorin 7:231 Vermeerin 20:10 Vermeersiekate 20:10 Vermisporin 28:125 antimicrobial activity of 28:125 Vernodalin 26:808,809 Vernolepin 4:584,585 synthesis of 4:584,585 Vernonia amygdalina 26:808;28:400 tick toxicity of 28:400 Vernonia brachycalyx 26:798,811 Vernonia chinensis 22:535 in convulsions in children 22:535 Vernonia galpinii 5:728 Vernonia hildebrandtii 22:535 in convulsions in children 22:535 Vernonia patula. 22:535 Verolide 26:808 Verongamine 25:721 Verongia sp. 10:632 Verongia spengelii 5:410 Verongula gigantea 25:721 Veronica persica 25:781 Verrucarin A 26:464 Verrucarinolactone 3:252-259 synthesis of 3:252-259 Verrucarins 30:743 arenavirus junin 30:743 herpes simplex virus type II (HSV-2) 30:743 Verrucarol 6:225,227,237,241 2,13-deoxygenation of 6:234 Claisen rearrangement by
848
10:426-428 synthesis of 10:426-428 (+)-Verrucosidin 10:439 Verrucosin 26:228 of antiviral activity 26:228 Verrucosin A-B 17:15 Versicoside A 7:288,293; 15:47 Versicosides A-C 7:293 from Arterias amurensis versicolor 7:287 Vertebrate toxicity 21:98 Vertebrate-parasitic nematodes 26:428 Verticelline 11:25-28 synthesis of 11:26-28 Verticillane 12:182,183;18:607 synthesis of 12:182,183 Verticillium alboartrum 25:299,302, 307,311 Verticillium balanoides 27:868 Verticillium biguttatum 21:205 Verticillium dahliae 21:205,239;25:305, 307,311 Verticillium lecanii 28:404 Verticillium sp. 21:221 Verticillol 11:28,12:181 from Seidopitys verticillata 20:107 Verticillol 23:489,493 Verticillol norketodiepoxide 23:493 Vertinoids 21:206 (-)-Vertinolide 16:700 synthesis of 16:700 Vesicant activity 1:365 Vesicular glutamate transporters 25:538 Vesicular monoamine transporter type 2 (VMAT2) inhibitor 30:380 Vesicular monoamine transporters 25:538 Vesicular stomatitis virus (VSV) 26:223;30:743,752 replication of 30:743 Vesiscular stomatitis 25:779 Vesititol 28:224 anti-microbial activity of 28:224 Vespa orientalis 4:494,19:133 Vespidae 6:421
Vestitol 28:243 anti-Helicobacter pylori activity of 28:243 Veterinary medicine 28:383 for ectoparasites control 28:383 Vetiver grass 28:399 for controlling ticks 28:399 phetchabun as 28:399 'Si Sa Ket' as 28:399 'Uthai Thani' as 28:399 Vetiver oil sesquiterpene 15:273 Vetiveria zizanioides 27:377 (-)-~-Vetivone 16:267 Vexibinol 25:612 Vezical hematuria 26:689 Viagra (sildenafil) 25:541 Vibrio algmolyticus 26:70 Vibrio anguillarum 23:164,238;25:877 Vibrio cholerae 4:195;25:521 Vibrio genera 29:311 Vibrio ordalii 4:195 tetraheptoses in 4:195 Vibrio sp. 21:259,310 Vibrio valnificus 25:718 Vibsanol 26:255 Vibumium dilatatum 4:712 Viburnum awabuki 26:255 9'-O-(-)-phlligenin from 26:255 vibsanol from 26:255 Viburnum suspensum 25:251,257,259 Viburtinal 7:458,459 from Viburnum tinus 16:302 from Viburnum opulus 16:302 Vicenin 7:228 Vicia angustifolia 29:599 Viciafaba L. 19:247;23:341;25:93; 26:748;27:218;29:609 Vicia sativa 25:93;29:591 Vicinal oxyamination reaction 11:61 1,2,3-Vicinal tricarbonyl unit 8:261-274 synthesis of 8:261-274 Vicinal tricarbonyls 8:261-274 Vicoa indica 29:89 Vicolides 29:89 activity in CTN bioassay system 29:89 Vietnamese ginseng 21:672 Vigabatrin 22:508 Vigna angularis 25:93;29:609
849 Vigna radiata 18:522 23- O- [3-D- gl ucop yrano sy 1 brassinolide from 18:522 Vigna unguiculata 25:93;29:617 Vignaticol 26:850 Viguiera gardneri 29:90 Viguirea aspillioides 26:810 (-)-trachyloban- 19-oic-from 26:810 Vikankata 23:656 Villagorgia rubra 21:260 Villagorgins 21:260 Villamine 13:396,397 Villastonine 13:383,392,397,404,429 synthesis of 13:405 X-ray analysis of 13:399 Villastonine N-4 oxide 13:392 Villosin A 630 Villosin B 23:630 Villosin C 23:630 Vilsmeier formylation 1:507,508; 18:233 Vilsmeier reaction 6:322 Vilsmeier's reagent 9:422-424 Vinamidine 2:389,390,398 Vinblastine 2:370,372,287,389,390; 4:29;8:283;12:179;13:633; 14:805-884;19:748;20:458;21:84, 264,488 ;22:33 ;24:269;25:269; 27:744,781,782 anticancer activity of 14:805 Atta-ur-Rahman's first synthesis 14:850-859 Buchi's synthesis of 14:868,869 from catharanthine 14:854-858 from Catharanthus roseus 8:283;14:805 Gorman's synthesis of 14:862-864 Kuehne's synthesis of 14:831-849 Kutney's synthesis of 14:805-821 Magnus's synthesis of 14:821-830 N-demethyl deacetylvindoline from 14:862,863 Potier's synthesis of 14:869-873 3'-oxovinblastine from 14:813
Schill's synthesis of 14:861,862 synthetic approaches to 14:805-884 synthesis of 5:187-189 Takano's synthesis of 14:865-867 velbanamine from 14:862,863 Atta-ur-Rahman's first synthesis of 14:850-859 biosynthesis of 4:31 Buchi's synthesis of 14:868,869 deacetylvindoline from 14:862, 863 first synthesis of 4:32 from anhydrovinblastine 14:820, 821,871 from catharanthine 14:854-858 from Catharanthus roseus 8:283;14:805 from leurosine 14:860 Gorman's synthesis of 14:862-864 Kuehne's synthesis of 14:831-849 Kutney's synthesis of 14:806-821 Magnus's synthesis of 14:821-830 Potier's synthesis of 14:869-873 Schill's synthesis of 14:861,862 synthesis of 5:185-187 synthetic approaches to 14:805-884 Takano's synthesis of 14:865-867 velbanamine from 14:862,863 Vinca major elegantissima 1:124 Vinca minor 2:370;26:144;29:573 (-)-eburnamonine from 8:283 (+)-vineamine from 8:283 Vinca rosea (Catharanthus roseus) 24:269 Vincadiffine 5:125 9 -Vincadifformine 14:833;19:92 from Panadaca caducifolia 19:90 Vincadifformine 2:370;19:101-102,115 derivatives of 19:115 enantioselective synthesis of
850
4:40,41 from Vincadifformis 19:90 preparation of 19:101 synthesis of 14:635,636 total synthesis of 19:93 transformation of 19:89 (-)-Vincadifformine 4:35;5:126 conversion to vindoline analogues 4:35 20R-pseudovincadifformine 5:123 20S-pseudovincadifformine 5:125 (+)-Vincadifformine 5:124 Vincadifformine-type alkaloids 5:92 apodine 5:92 apodinine 5:93 cylindrocarpidine 5:93 O-demethylpalosine 5:92 (+)-demethylaspidospermine 5:92 desoxoapodine 5:92 10-hydroxy' 11-methoxytabersonine 5:93 12-demethoxycylindrocarpidine 5:92 12-hydroxyvincadifformine 5:92 14,15-dihydroxyvincadifformine 5:92 5-oxo-cyclindrocarpidine 5:93 haxuntine 5:93 hazuntinine 5:93 homocylindrocarpidine 5:93 lochnericine 5:92 mehranine 5:90,92 (+)-minovincine 5:92 (+)-3-oxo-minovincine 5:92 tabersonine 5:92 (+)-vincadifformine 5:90,92 (-)-vincadifformine 5:92 Vincadine 14:635,636 synthesis of 14:635,636 Vincaleukoblastine 13:634 Vincamajine 9:183 (+)-V incamine 14: 726 from Oppolzer's aldehyde 14:726 synthesis of 14:726 16-epi-Vincamine 2:370
Vincamine 2:370;8:283,292,13:660; 19:89 from Vinca minor 8:283;13:660 synthesis of 1:117,118;5:187, 189,190;14:635,636 (-)-Vincamine 5:127 (-)-16-epi-Vincamine 5:127 (-)-21-epi-Vincamine 5:127 (+)-Vincamine 5:127 (+)-16-epi-Vincamine 5:127 (+)-21-epi-Vincamine 5:127 Vincamine-eburnamine type alkaloids 10:411 Vincamine-related alkaloids 8:266 synthesis of 8:266 Vincamine-type alkaloids 5:107,108 Vincaminoreine 14:635,636 synthesis of 14:635,636 Vincamone 19:90 Vincanicine 1:36;9:193 Vincanidine 1:36;5:126 Vincarpine 1:124 Vincomycins B2 5:594,595 Vincosamide 26:115,116,117,127 Vincosan-type akaloids 5:71 (-)-vincamine 5:108 (+)- 14,15-dehydro- 16-epivincamine 5:108 (+)-16-epi-vincamine 5:108 (+)-apovincamine 5:107,108 (+)-vincamine 5:108 14,15-dehydro- 12methoxyvincamine 5:108 vincamine 5:108 Vincoside 26:127,128,130,135,136 313-H Vincoside 26:97 Vincovaline 14:840-846 enantioselective synthesis of 14:840-846 Vincristine 2:390,398;9:387;11:5, 12:396;13:633 ;20:458;21:84,488; 22:24,29,33 ;24:269,405 ;27:778 anticancer activity of 14:805 Atta-ur-Rahman's first synthesis of 14:850-859 biosynthesis of 4:31 Buchi's synthesis of 14:868,869 first synthesis of 4:32 from catharanthine 14:854-858
851 from Catharanthus roseus 8:283;14:805 Gorman's synthesis of 14:862-864 Kuehne's synthesis of 14:831-849 Kutney's synthesis of 14:805-821 Magnus's synthesis of 14:821-830 N-demethyl deacetylvindoline from 14:862,863 oxidation of 27:778 Potier's synthesis of 14:869-873 Schill's synthesis of 14:861,862 synthetic approaches to 14:805-884 synthesis of fi: 187-189 Takano's synthesis of 14:865-867 velbanamine from 14:862,863 19-epi-Vindoline 2:375 Vindoline 2:370,371,373,375,390,392, 398,399,400,401,402;5:185; 14:806-884 ;22:33 ;26:1047,1048; 27:747,782 conversion to 16'decarbomethoxy-20'-deoxy vinblastine 4:30,31 coupling with 16-hydroxydihydrocleavamine 4:30,31 coupling with catharanthine 4:32 enantiosynthesis of 4:38,39 in biosynthesis of vinblastine 4:31 synthesis of 4:55 Vindoline analogues 4:29-81 synthesis of 4:29-81 Vindoline-N-methylamide 14:870,871 from 15,20S-dihydrocatharanthine N-oxide 14:870, 871 Vindolinine 2:377;9:183,186 Vindorosine 4:34,55 synthesis of 4:34,55 Vineomycin A~ 11:113 antibacterial 11:113 antitumour 11:113
from Streptomyces matensis 11:113 Vineomycin A1 5:594,595 from Streptomyces matensis subsp, vineus 5:593 Vineomycin B2 10:370 synthesis of 10:370 Vineomycin B2 methyl ester 11:140 Vinervine 1:35 Vinervinine 1:35 (-)-Viniferal 26:570 Viniferifuran 26:570 ~-Viniferin 16:565;23:533,560 antifungal agent 16:565 synthesis of 16:565 (-)-c-Viniferin 26:530 (+)-~-Viniferin 26:530,532,551 (-)-c~-Viniferin 26:535,560 Viniferin 26:552,569 2-Viniferin 26:552,570 ~-Viniferin 26:553,560 (+)-c~-Viniferin 26:558,560 (-)-trans-g-Viniferin 26:560 (+)-c~-trans-g-Viniferin 26:560 cis-~-Viniferin 26:567 1,2-Viniferin 27:767 e-Viniferin 27:767 (+)-~-Viniferin 27:855 ~-Viniferin diol 26:569 Viniferins 27:770,766 in spermatophytic plants species 27:770,766 Vinlogous phenylseleno etherification 12:11,12,25 Vinorelbine 26:1048,1049 Vinorine 13:400,402 Vinoxine 1:62 total synthesis of 1:62 Vinrosidine 14:857,859 synthesis of 14:857,859 Vinyl 4H-1,2 dithiin 23:4593Vinyl 4H-1,3 dithiin 23:4592Vinyl acetate 1:562,563 reaction with methyl lithium 1:562,563 Vinyl acetate 1:562,563 reaction with methyllithium 1:562,563
852
Vinyl azides 1:165 preparation of 1:165 Vinyl carbanions 11:440,441 nucleophilic addition with 11:440,441 Vinyl carbene 3:27 (Z)-Vinyl chromium 30:10 Vinyl cuprate addition 3:189,190, 195,196 Vinyl ether 14:487,488 from (3S,5S)-2,6-dimethyl-3,5heptanediol 14:487,488 from (2R,4R)-2,4-pentanediol 14:487,488 Vinyl iodide 12:48-53;30:8 from D-glucose 12:37,38 from 1,2,5,6-Di-Oisopropylidene D-glucose 12:41 from D-ribose 12:50 palladium-catalyzed coupling reaction of 30:8 (Z)-Vinyl iodide 30:20 oxidation of 30:20 condensation of 30:20 Vinyl palladation 16:371 of 4-cyclopentene- 1,3-diols 16:371 Vinyl radical cyclization 12:24 Vinyl stannane 1:490 synthesis of 1:490 from tributyltin/acetylene 1:490 Vinyl sulfoxides 10:673-676 cyclization of 10:673-676 Vinyl sulfoximines 10:679 cyclization of 10:679 Vinyl tricarbonyl hydrate 8:267-272 2-Vinyl-4H- 1,3-dithiin 23:469 Vinylacetyl chloride 14:453,454 condensation of 14:453,454 with 9-chloro- 1-p-menthene 14:453,454 Vinylallenes 4:522 sigmatropic rearrangement 4:522 Vinylation 6:86,87 in 7,20-diisocyanoadociane synthesis 6:86,87 in 14-epi-upial synthesis 6:67,68 of olefins 16:416
Vinylaziridination 3:55 [2+3] 3:55 [4+1] 3:55 Vinylaziridine 3:50 cleavage of 3:50 4-Vinylcatechol 25:925,926 Vinylcatechol 25:927 Vinylcyclobutane 3:465,466 rearrangement of 3:465,466 Vinylcyclopropane isomerization 3:15 Vinylcyclopropane-cyclopentene 3:38, 44,47 rearrangement 3:38,44,47 Vinylcyclopropanes 3:38,44,47 from 1,4-dienes 3:38,44,47 pyrolysis of 3:34 via allylic S N 2 process 3:47 Vinylcyclopropylcarbene 14:627 6-Vinyldihydropiran-2-carboxylate template 30:465 Vinylfurans 25:694 Vinylic anions 4:497 inversion of 4:497 Vinylic ethers 4:116 hydroboration of 4:116 Vinylic sulfoxides 4:501,502 for synthesis of esterone 4:501,502 for synthesis of vitamin E 4:494501 Vinylketene acetals 14:503,504 asymmetric Diels-Alder reaction of 14:503,504 Vinylnitrene cyclization 1:178-180 Vinylogous amide susbtrates 18:376, 386 Vinylogous carbamate substrates 18:344,377 Vinylogous urea substrates 18:363 Vinylogous urethane 25:10,11,33,34 Vinyloxetane 10:588,589 Vinyloxiranes 3:55-58 synthesis of dihydrofurans 3:55-58 Vinyloxyborane-imine reaction 4:465,466 carbapenem precursors by 4:469 stereochemistry of 4:467,468
853 Vinylpicoline 14:437,438 bis-annelating agent 14:437,438 Vinylpyridine 14:438 Vinylsilane 8:242 A1C13 catalyzed Friedel-Crafts acylation 8:242 synthesis of 8:242 Vinylsilane-medicated bicyclization 13:615 Violanin 5:646 Violaxanthin 20:575,727;30:530 Violer~hrin 30:518,519 structure of 30:519 Viologen oxidoreductase 20:840,858 Violoxanthin 7:98 Viral 2'-deoxythymidine kinase 30:395 Viral adhesion 16:113 Viral diseases 30:732 Viral DNA 30:226 integration of 30:226 Viral DNA polymers 30:395 for herpes simplex virus 30:395 for varicella-zoster virus 30:395 phosphorylation of 30:395 Viral envelope glycoproteins 30:404 natural sulphated polysaccharide (PS) 30:404 Viral glycoprotein 27:109 haemagglutinin 27:109-112 neuraminidase 27:112-114 Viral glycoproteins 25:388 Viral infections 30:394,742 therapy of 30:394 Viral mutation 30:407 Viral proteins 24:477,478 Viral sialidase 16:112 Virantmycin 29:339 antifungal activity of 29:339 antiviral activity of 29:339 effects on lipids peroxidation 29:339 inhibition of glutamate toxicity 29:339 Virenamide 25:888 Virenamide A 23:244;28:644 as cytotoxic linear peptides 28:644 Virenamide A-E 25:888
Virenamide B 23:244;28:644 as cytotoxic linear peptides 28:644 Virenamide C 23:244;28:644 as cytotoxic linear peptides 28:644 Virenamide D 23:244 Virenamide E 23:244 Virgaureasaponin E 21:641,651 Virgilia 26:1157 Virginiamycin 5:606 Viridifloric acid 1:260,261 enantioselective synthesis of 1:260,261 Viridiflorine 1:267 synthesis of 1:267 Viridin antibiotics 21:238 Viridiofungin A 24:433,434 Viridiofungins 21:191,192,196 Viroid-like RNA 30:406 Viroids 24:482 Virola elongata 17:319;22:356 Virola oleifera 26:228 3,4,3',4'-tetramethoxylignan-7-ol from 26:228 oleiferin-B from 26:228 oleiferin-F-from 26:228 oleiferin-G from 26:228 Virola sebifera 18:726;22:356;26:186 Virola surinamensis 26:230 grandisin from 26:230 veraguensin from 26:230 Virosecurinine 21:69 Virucidal activity 21:665 Virucidal agents 30:627 hypericin as 30:627 pseudohypericin as 30:627 Virus 30:393,394 adeno- 30:393 herpes- 30:393 pox- 30:393 replication of 30:394 Virus replication 30:395 role of 30:395 Virus-cell binding inhibitors 30:398 inhibition of 30:398 Virus-specific treatment 30:407 Virustatic pharmaceuticals 17:421 Viscidulin 1 5:678
854
Viscidulin A-C 7:236 Visconolides 20:180 Vismia 22:580 Vismia decipiens 4:378 Vismiaphenone A 378,379 Vismiaphenone B 4:378,379 Vismione D 7:419 antimalarial activity of 7:424 antiproliferative activity of 7:419 Vismione F 7:419 Vismiones 7:418,419 Visnadin 23:351,357 Visnea mocanera 21:548 Vitaceae 27:766 Vitamin A 7:114;9:412,413;20:569, 570,605,720,748,750;23:271,739 by diene synthesis 6:308 synthetic approaches to 4:526-531 Vitamin A synthesis 28:71 by Baadische Anilin 28:71 by Hoffmann-LaRoche 28:71 by Rhone-Poulenc 28:71 by Soda Fabrik 28:71 Vitamin A~ 30:520 dietary source of 30:520 for development 30:520 role in visual process 30:520 structure of 30:520 Vitamin BI2 9:591-609;16:150 evolutionary aspects of 9:591-609 mechanistic aspects of 9:591-609 synthesis of 16:150 Vitamin B-12 intermediates 4:674-677 Vitamin C 23:739 Vitamin C,E,K,A,D 25:236 Vitamin D 9:509-511,515;10:43-75; 30:498 adverse effect of 30:498 semi-synthesis of 17:621 stereoselective synthesis of 10:43-75 synthesis of 4:522;11:379-408 Vitamin D aldehyde 10:52 synthesis of 10:52 Vitamin D analogues 30:483,484, 485,489
in vivo activities of 30:484 metabolism of 30:485 pharmacokinetic properties of 30:484 structure-activity relationships (SARs) of 30:483 synthesis of 30:489 Vitamin D analogues synthesis 30:485-494 Vitamin D derivative 30:489,491 synthesis of 30:491 Vitamin D metabolites 14:471 stereoselective synthesis of 14:471 Vitamin D receptors 9:512 Vitamin D response elements (VDREs) 30:496 promoter of 30:496 Vitamin D2 9:510,513,521,522,524; 10:43,63,64;11:381 ;30:484,490 role in bone calcium mobilization 30:484 role in intestinal calcium transport 30:484 role in rickets 30:484 synthesis of 30:490 Vitamin D3 11:380;30:490,493 degradation of 4:523 fluorinated analogs of 9:517 metabolism of 9:514,521 total synthesis of 9:510 X-ray crystal analysis of 9:510 synthesis of 30:490,493 Vitamin D4 30:485,490 synthesis of 30:490 Vitamin D5 30:490 synthesis of 30:490 Vitamin O7 30:490 synthesis of 30:490 Vitamin deficient rat serum DBP 30:496 competitive binding to 30:496 Vitamin K 26:638 Vitamin KI (naphthoquinone) 29:585 effects on coagulation 29:585 Vitamin L2 6:351 Vitamin P 23:740 Vitamins 2:366,367 semi-synthesis of 17:620,640
855
Vitamin C 20:34 Vitamins E 4:494-501,9:580,20:34 Vitamins E and K 14:478,479 synthesis of 14:478,479 Vitellogenin 22:376 (+)-Viternal 16:257 Vitex lucens 29:579 Vitex negundo 22:535 for convulsions in children 22:535 Vitex peduncularis 29:84 Vitex rotundifolia 29:101 Vitexin 25:594,595 Vitis vinifera 20:721,723,724,731; 21:204;26:530;27:756,757;29:585 (+)-Vitisfuran A 26:570 (-)-Vitisfuran B 26:570 trans-Vitisin A 26:558,568 Vitisin A 26:568 (+)-cis-Vitisin A 26:568 (-)-trans-Vitisin B 26:559,569 (-)-cis-Vitisin B 26:569 (+)-Vitisin C-E 26:559,569 (-)-Vitrenal 16:260 Vittatine 20:352,20:356 Viverra civetta 8:219 VLDL-LDL 21:671 Vmax values 30:95 oflipase activity 30:95 Vminalol 29:585 effect on CHY 29:585 effects on HIV- 1 protease 29:574 effects on collagenase 29:583 VO-(acac)2-TBHP 10:39,40 epoxidation with 10:39,40 of allylic alcohols 10:39,40 Voabasine 5:112 Voabasine-type alkaloids 5:77 10-hydroxy-16-epi-affinine 5:77 16-epi-affinine 5:75,77 16-epi-vobasinic acid 5:77 3-(2-aminoethylthio) desoxovobasine (pagisulfine) 5:78 accedine 5:77 affinine 5:75,77 anhydrovobasindiol 5:77 dregamine 5:75,77
dregaminol 5:77 dregaminol-methylether 5:78 Nl-demethyl- 16-epi-accedine 5:77 N~-methyl-16-epi-affinine 5:77 pagicerine 5:78 pagisulfine 5:75 perivine 5:75,77 tabemaemontanine 5:75,77 tabemaemontaninol 5:75,77 vincadiffine 5:78 voacarpine 5:75,77 vobasinol 5:75,77 Voacamidine 5:129 Voacamine 5:113,125 Voacamine-N'4-oxide 5:129 Voacanga thouarsii 22:535 19-epi-Voacangarine 9:174 Voacangine 5:99,127,174 Voacangine hydroxyindolenine 5:100, 128 16-epi-Voacarpine 15:466,467 from Gelsemium elegans 15:469 Voacarpine 5:127 Voachalotine 5:75,127,179 Voacorine 5:123 19-epi-Voacorine 5:129 Voacristine 5:127 hydroxindolenine 5:101 19-epi-Voacristine 5:128,130 Voacristine hydroxyindolenine 5:128 Voacristine pseudoindoxyl 5:128 Voaphylline 5:124,172 Voaphylline hydroxyindolenine 5:126 Voaphylline- 14,15-diol- 19-hydroxy 5:126 Voaphylline- 14R, 15S-diol 5:124 Voaphylline-type alkaloids 5:90 Voaphylliine 9:171 Vobasine 9:181,182,503 16-epi-Vobasinic acid 5:127 Vobasinol 5:111,123,171 Vobparicine 5:123 Vobparicine-N4-oxide 5:123 Vobtusine 5:124 Voglibose 22:177 Volatile components 26:298;27:700 of olive oil 27:700 of saffron 26:298
856
Volatile compounds 23:641 Volatile oil 30:605 constituents of 30:605 Voltage-gated Ca2+channels 25:517 Voltage-gated ion channels 25:520 Voltage-gated K + channel 25:531 Voltage-gated Na + channels 25:533 Voltage-sensitive calcium channel 30:203 blockade of 30:203 by ginsenosides 30:203 Volubilide 30:661 13CNMR of 30:661 2DNMR experiments of 30:661 IHNMR of 30:661 HREIMS of 30:661 molecular formula of 30:661 X-ray data of 30:661 Volubilide formation 30:663 structure of 30:663 mechanism of 30:663 Volucrispora aurantiaca 29:266 Volucrisporin 29:266,295 biosynthesis of 29:295 structure of 29:266 Volumetric methods 21:508 Volutamides 25:757 Volutamides A-E 25:786 Volvariella volvacea 5:287,288,290, 316,320;23:115 Vomifoline (peraksine) 13:389 Vomitoxin (desoxynivalenol) 9:204-207,215,216 Von Braun degradation 18:51 Voriconizole 22:60 VPC coinjection experiments 14:684 VSV 24:524 activity of actinoplanic acids against 24:524 Vulgarin 7:233 Vulgarol 7:209 from Artemisia vulgaris 7:208 (-)-Vulgarolide 18:19,20 Vulgarolide 27:594 Vulgarone A 27:588 Vulgarone B 9:534;27:588 Vulgaxanthine I,II 20:725 Vulvovaginitis 2:422
"W" arrangement 14:742 Wachendorfia 17:372 Wacker oxidation 10:308,309,316; 13:494;14:560,561,584;16:481; 18:273,283,633 ;19:29 in (+)-brasilenol synthesis 6:7 Wacker process 11:238,241,246;16:85 Wadsworth-Emmons chain extension 13:596 Wadsworth-Emmons condensation 1:52,60;13:573 Wadsworth-Emmons cyclization 23:493 Wadsworth-Emmons reaction 1:176, 177;7:480;11:89;12:328;16:349; 18:897;24:720 intramolecular 11:108 Wadsworth-Emmons-Horner reduction 20:450 Wadsworth-Homer-Emmons olefination 26:1230 Wadsworth-Horner-Emmons reaction 1:401,402 Wagner-Meerwein rearrangement 4:38, 39,626-628,633,634,637,643 ;6:52, 149,181 ;12:37,131,147,236,245,248, 356,363-368;24:30-32 of end-6-silyloxy-isoborneol 16:147 1,2-Wagner-M," rweinshift 18:882 Waiakeamide 2,d:684 as cyclic hexapeptide 28:684 Waitzia acuminata 25:251 Waixenicin-A 5:370 Wakayin 23:259 Waksmania aerata 27:219 Wallenberg's procedure 6:298,299 warburganal 6:108 WALTZ sequence 15:205 Warabi 26:691 Warangolone 25:541 ;27:844,845 Warburganal 29:87 activity in skin-1 assay system 29:87 Warbugia stuhlmannii 17:234 Warbugia ugandensis 17:234 (-)-Warburganal 14:413-421 antifeedant properties 14:413-421 by Swem oxidation 4:418,425
857
from (+)-confertifolin 4:418 from 1-abietic acid 4:416 from manool 4:418,420,424,425 from Warburgia stuhlmanii 4:403 from Warburgia ugandensis 4:403 synthesis of 4:403,416-418,424; 14:413-421 Warburganal 24:175-182 synthesis of 24:175-182 Warburganol 2:288 Warburgia stuhlrnanii 4:403,427; 24:182 Warburgia ugandensis 4:403,427; 22:635;24:182 Warfarin 23:359 Warren procedure 3:257 Warts 30:405 Wartski imine Diels-Alder reaction 16:458 Watersipora subtorquata 28:620 5,7-dihydroxy-6-oxo-6Hanthra[ 1,9-bc]thiophene- 1carboxylic acid from 28:620 Water-soluble materials 17:481 Water-soluble polymers 30:395 biopolymers in 30:395 Watt synthesis 14:678-681 of taxodione 14:678-681 Wax esters 9:452,455,463,470 Wayakin 25:707 Webiol 5:725,727 angelate of 5:725,727 Wedelia asperrirna 20:8 Wedelia glauca 20:8 Wedelia paludosa 26:810 ent-kaura- 16-en- 19-oic acid from 26:810 Wedelia scaberrima 7:427 Wedeloside 20:8 Weight loss 30:56 due to cancer drugs chemotherapy 30:56 Weiler's reaction 11:115 Weinerb reaction 26:1239,1243 Weinreb's amide 30:473 synthesis of 30:473
Weisiensin A 15:112,120 13C-NMR of 15:134 from Rabdosia calcicolus 15:171 from Rabdosia nervosa 15:173 from Rabdosia weisiensis 15:175 ~H-NMR of 15:127 Weiss reaction 18:286 Weiss-Cook condensation 3:23,24 Welch procedure 10:308,309 demethoxycarbonylation by 10:308,309 Welch synthesis 6:17 of isozonarol 6:17 of zonarol 6:17 Wender synthesis 13:445,446 of 7-methoxymitosene 13:445,446 Wender's [4+4] cycloaddition strategy 12:189 Wenkert's enamine 1:113;14:727 synthesis of 14:727 Wenkert-type enamine 8:284,285 Weolignans 27:765 biological activity of 27:765 Wessley-Moser rearrangement 2:133,665 Western blotting analysis 15:449 Wharton reaction 10:47 Wharton rearrangement 10:36,37 Wheat cystatins 29:594 effects on cathepsin B 29:594 effects on cathepsins 29:594 effects on chymopapain 29:594 effects on cysteine proteases 29:594 effects on ficin 29:594 effects on papain 29:594 Wheat flour 28:259 vanillic acid in 28:259 syringic acid in 28:259 (-)-trans-Whisky lactone 14:272,273 from levoglucosenone 14:272, 273 synthesis of 14:272,273 (+)-trans-Whisky lactone 19:152 Whistler method 6:367
858 White synthesis 12:15,27,28 of avermectin B la aglycone 12:15,27,28 Whole insect assays 29:29 20E 22-O-benzoate tested in 29:30 cyasterone activity in 29:30 24(28)-dehydromakisterone A activity in 29:30 2-deoxy-20-hydroxyecdysone activity in 29:30 20E 2,25-dibenzoate tested in 29:30 ecdysones tests in 29:30 integristerone A activity in 29:30 nusilsterone activity in 29:30 polypodine B activity in 29:30 ponasterone A activity in 29:30 rapisterone D activity in 29:30 turkesterone activity in 29:30 Wieland Miescher ketone 24:175-213 bioactive terpenes from 24:175-213 Wieland-Gumlich aldehyde 9:183 Wieland-Gumlich diol 1:38,39 (+)-Wieland-Miescher ketone 10:409 Wieland-Miescher ketone 6:18,19; 11:16-18,50,51,53;17:608,29 absolute configuration of 17:53 endesmanes from 6:18,19 endesmanolides from 6:18 synthesis of 6:18,19 Wierenga intramolecular alkylative closure 3:325,326 Wiesnerella denudata 2:280 Wighteone 28:226,229 anti-human immunodeficiency virus (HIV) activity of 28:226 biological activity of 28:229 Wihtacinstin 20:246 Wihtangulatin A 20:246 Wikstroemia indica 26:270;27:833 activator from 27:833 (+)-nortrachelogenin from 26:270 Wikstromol 26:192
Wilcox and Gaudino 29:460,461 carbaketofuranose synthesis by 460,461 Wilcoxon test 2:434 Wild plasmodium constituents 29:236 6-alkyl-4-methoxypyran-2-one s ceratiopyron A as 29:237 ceratioflavin A as 29:237 Wildman procedure 4:19,22 Wilfordic acid 23:674 Wilfordine 18:772 from Maytenus rigida 18:771 Wilfordine 23:678 Wilforic acid A 30:676 13C-NMR spectra of 30:677 ~H-NMR spectrum of 30:676 IR absorption bands of 30:676 structure of 30:677 UV absorption bands of 30:676 Wilforic acid B 30:639 HREIMS spectrum 30:639 structure of 30:639 Wilforic acid C 30:640 ~3C spectrum of 30:640 Wilforine 23:678 Wilforlide 23:696 Wilforol E 23:682 Wilforol F 23:682 Wilfortine 23:681,678 Wilkinson catalyst 6:10,11;9:459,474; 10:39;11:354,363 ;12:8,35,37,38,40, 50,267,311;13:564;18:207;19:500 for decarbonylation 16:340, 345,350 Wilkinson complex 11:363 decarbonylation with 11:363 Willgerodt reaction 14:681,682 Williams approach 12:28-30 for avermectin oxahydrindene subunit 12:28-30 Williams enantioselective synthesis 6:15 of (-)-zonarene 6:15 Williamson ether synthesis 6:386 Willow (Salix species) 30:192 analgesic properties of 30:192 anti-inflammatory properties of 30:192 antipyretic properties of 192
859
Wilson synthesis 10:48 Winstein spirocyclization 3:325 Wiothanicandrin 20:242 Wistaria brachybotrys 21:642;24:221, 223,224,241,247,261 ;25:93,222 Wistariasapogenol A 25:97 Wisterlasaponm A 21:642 Wistarlasaponln B3 25:95 Wistarlasaponm A2 25:97 Wistarlasaponln A3 25:97 Wistariasaponm BI 15:206 Wistarlasaponm B2 25:95 Wistariasaponln C 25:222 Wistanasaponm D 25:97,116,118 Wisterlasaponm G 21:642 with OsO4 1:404,405 Wistariasaponin YCI 25:96,104 Wistariasaponin YC2 25:96 Wistariasaponins 25:222 Wistarin 6:8 from Ircinia wistarii 6:8 Wisteria floribunda 24:273 Withaferin A 20:138,180,194,204,214, 215,220,234,245 Withaferoxolide 20:221,223 Withania ashwagandha 22:535 Withania coagulans 20:238 Withania somnifera L. 20:138,180,181, 234,238,241,246,247;22:535 as antiepileptic 22:535 as sedative in epilepsy 22:535 Withanicandrin 20:182,223,224 Withanolide 19:463,470 antitumor activity of 19:470 biological activities of 19:470 insect antifeedant properties of 19:470 novel structure of 19:470 Withanolide D 20:180 Withanolide E 20:204,214,220, 221,245,246 Withanolide G 20:139 Withanolide glycosides 20:191 Withanolide M 20:180,242 Withanolide Q 20:180,20:241 Withanolide R 20:180.241 Withanolide S 20:245 Withanolide Y 20:180 Withanone 20:220
Withaperuvin F 20:181 Withaphysalins 20:241 Withaphysalins A 20:189 from Physalis minima 20:189 Withaphysalins B 20:189 from Physalis minima 20:189 Withaphysalins C 20:189 from Physalis minima 20:189 Withasomniferol 20:181 Withasomnine 1:343 synthesis of 1:343 Witkop photocyclization 1:52 Wittig condensation 3:462;12:281; 13:620;14:112;19:59;20:582 of olefin 5:708 in (+)-sinularene synthesis 6:85 Wittig coupling 10:9,15;13:617 in 7,20-diisocyanoadociane synthesis 6:86,87 Wittig cyclopropanation 21:397 Wittig homologation 3:268,269;11:100, 101 ;18:196,216;21:397 Wittig methodology 21:391 Wittig methylenation 6:185,165; 18:177;19:42 Wittig olefin 30:443 formation of 30:443 Wittig olefination 1:460,461,473,487, 488;4:123,163,164,169,176,252,279, 280,285,286;8:413 ;10:429;12:327, 330;13:604;14:129,132,460,461; 16:377,378,388,484 ;18:8 ;19:22,137; 21:388,397,415,428,439,440,445; 24:8;26:1234 for fused lactone nucleoside synthesis 4:254 in (+)-precapnelladiene synthesis 6:39 in (+)-stoechospermol synthesis 6:39 in nakafuran-9 synthesis 6:70 in nine-carbon sugars synthesis 4:180 of amino aldehyde 16:490 of D-galacto-hexodialdopyranose 4:163,164 of D-lyxo-pentodialdofuranoside 4:176 of heptodialdopyranose
860
derivative 4:180,181 of hexodialdopyranoside derivative 4:169 of pentodialdofuranose 4:190 of t-butyl 2-C-methyl-2,3,4,7tetradeoxyhept-6-ulopyranoside 10:414 with N-pentylidene triphenylphosphorane 5:822 Z-selective 4:125 Wittig reaction 1:221,399,400,447,448, 531,533,535,538;3:258,288,488; 4:126,150,175,202,553-578;5:828;
6:16-19,21,61,68,125,157,158,225, 226,269,279,281,285,286,301,302, 425,558,559;8:46,146,147,161-164, 223,224;9:351,352,354,356,358,360, 362;10:48,55,68,166,308,309,389 392,510;11:367;12:319,321,350,488; 13:32,35,37,125,141,175,200,208, 482,508,594 ;16:4,39,60,85,248,352, 702; 18:178,233,234,255,256,288, 297,618;19:10,20,43,72,267,367, 373,396,495;20:563,566,567,571, 572,578,584,586-592,594,599,601, 602,606,759;21:380,412,446;24: 7,188,190,719,720;26:65,66,70,72, 73,75,81,83-91 ;30:146,442,443 in 3-deoxy-2-ulosonic acids 30:443 C-glycosides by 3:218-220 hydroxyl directed 1:406,407 intramolecular 4:573,575 of iodide 14:556,557 of aldehyde 8:163,164,223, 224;19:495 of glutarimide 14:560 of ketone 8:162 of pyrrolidine derivative 14:556,557 of bromodecanal 26:83 of 8-formyloct-5-enoate 26:86 of (E)-5-methyltetradec-4-enal 26:72 of 12-hydroxy-2-methyldodecanal 26:70 of 6-methyl-2-heptanone 26:65 of 7-methyl-2-heptanone 26:65 of 5-methyl-2-hexanone 26:66
of 5-pentadecenal 26:75 stereoselective 12:12 stereoselectivity 4:175 unstabilized 1:406,407 with Corey reagent 19:452 with ethyl (triphenylphosphoranylidene) acetate 14:553,554 with formylmethylene triphenyl phosphorane 1:535,536,538 with glutaric dialdehyde 14:560 with heptylidene triphenylphosphorane 5:828 with hexylidenetriphenylphosphorane 19:495 with sugars 3:218-220 Wittig reagent 4:126;158;6:71;10:63; 11:72,78;16:64;19:57;30:15 conformational models 3:248, 252 in lactone synthesis 3:252,255 in synthesis of higher-carbon sugars 4:158 of secondary allylic ethers 3:249 of tertiary allylic ethers 3:251 of zirconium enolates 3:241 of ot-allyloxy anions 3:248-250 stereochemical induction 3:248252 Wittig reduction 21:397 Wittig ylide 6:181,183 Wittig-Horner chain extension 21:390 Wittig-Horner condensation 11:159,298 Wittig-Homer cyclization 12:292 intramolecular 12:292 Wittig-Horner homologation 18:333 Wittig-Horner olefination 11:431-435 Wittig-Horner reaction 4:602,603; 7:484;10:673;12:324,462;18:247, 623;19:256;29:427 marine alkaloids synthesis by 29:427 Wittig-Homer reagent 19:84 Wittig-methylenation 10:413 of L-mannose 10:413 Wittig-type condensation 21:409 Wittig-type methodology 21:383 Witting olefination 30:443 of sugar aldehydes 30:443
861
Wogonin 30:287 anti-inflammatory action of 30:289 structure of 30:287 Wolff rearrangement 19:18;21:438 of diazoketone 10:593-595 oxetane ring formation 10:592,593 Wolff ring contraction 6:178,179 Wolff-Kishner cyclization 1:58 Wolff-Kishner reaction 14:684 Huang-Minlon modification of 14:684 Wolff-Kishner reduction 2:235;4:416; 6:6,17,509;8:164,165;13:6,11,12, 21-23,403 ;14:277,278,359,417,419, 452,453,728;15:231 ;18:35;19:135; 21:707;24:175,176-179,199 Woodchuck hepatitis virus 20:535 Woodfordia fruticosa 23:404 Woodfordin A 23:404 Woodfordin B 23:404 Woodfordin C 23:410 Woodinine 23:267 Woodward reaction 19:363 Woodward reagent K 6:238,247,405 Woodward-Hofmann rule 2:128;3:401 Woorenoside-V 26:268 Wortmannin 6:219,220 Wounding-Induced Protein Kinase 26:946 Writhing test 30:207 activity of 13-narin-II8-4'-Omeeridictoyol in 30:207 role of biflavonoid in 30:207 Wulff 29:379 allocolchicinoids total synthesis by 29:379 Wurmbea sp. 6:158 xanthophils from 6:158 Wurtz coupling 9:344 Wuweizisu B&C 26:247,251,256,258, 263 Wyeronic acid 23:341,345
X14766A 29:317 against gram-positive bacteria 29:315
complexes of 29:317 from Mexican soil 29:317 Xanathomonas adaptation 25:399 Xanthan 26:1155;29:545 6-acetyl-mannose in 29:545 as exocellular polysaccharide gum 29:545 glucose in 29:545 glucuronic acid in 29:545 mannose in 29:545 4,6-pyruvate mannose in 29:545 rheological properties of 29:545 Xanthate 1:452,453 formation 1:452,453 rearrangement to dithiocarbonate 1:452,453 Xanthines 22:20,314 Xanthine oxidase 30:224 interaction with 30:224 Xanthium spinosum 25:781 Xanthium strumarium 27:346 Xanthoangelol 22:432 Xanthoangelo113 30:74,77 inhibitory mechanism of 30:74,77 effect on phenylephrine-induced vasoconstriction 30:74 Xanthoangelol E 30:76 effect on phenylephrine-induced vasoconstriction 30:74,76 inhibitory action of 30:76 Xanthobaccin A 28:140 as fungitoxic metabolite 28:140 Xanthobaccin B 28:140 as fungitoxic metabolite 28:140 Xanthobaccin C 28:140 as fungitoxic metabolite 28:140 Xanthocephalum linearifolium 25:251 Xanthoceras sorbifolia 7:139,141; 29:575 triterpenoids of 7:139,141
Xanthocercis zambesiaca 24:917,918 Xanthochymol 22:658 Xanthocidin 14:602,603,610 Xanthohumol 27:928 Xantholignans 5:495,496 Xanthommatins 26:967,988-992,995 Xanthomonas 26:582,605
862
Xanthomonas c. pv. armoraciae 26:596 Xanthomonas c. pv. carotae 26:596 Xanthomonas c. pv. orizae 26:596 Xanthomonas c. pv. raphani 26:596 Xanthomonas campestris 5:314;12:401; 26:596,1154;29:545 Xanthomonas campestris pv. Vitians 26:596 Xanthomonas compestris pv. vesicatoria 25:399 Xanthomonas fragariae 26:596 Xanthomonas hortorum campestris pv. vitians 26:596,606 Xanthomonas maltophilia 23:474 Xanthomonas oryzae 12:398;25:395, 398 carboxylate against 12:398 Xanthone hypothesis 25:351 Xanthone a-mangostin 25:531,536 inhibitor of CaZ+-ATPase 25:536 Xanthones 5:495,595,705,706,759; 7:410,411 ;17:436;20:285;22:644; 23:343 ;24:503-509;25:350,351; 26:805,806;27:902;30:622 as antiviral compound 24:503-509 Claisen rearrangement of 4:368, 370-372 derivative of 5:759 from heartwood 30:622 from umbelliferone 4:385,386 Xanthonoids 5:758 Xanthonolignans 5:5 Xanthonolignoid kielcorin 22:662 Xanthoperyl methyl ether 14:673, 674,676 Xanthophyll cycle 30:521 C40-Xanthophylls 20:607 Xanthophylls 7:318,360 Xanthopurpurin 3-methylether 26:665 Xanthopurpurin 26:657,665,676 Xanthopurpurin dimethylether 26:665 Xanthorrhizol 5:802,804;23:830;24:288 synthesis of 5:802 Xanthotoxin 9:402;10:153;23:352,353 from Limonia acidissima 20:497 Xanthoxyletin 2:118;9:288,289;20:497 Xanthoxylol 26:226
Xanthoxylon hostile 22:535 for epilepsy 22:535 Xanthurenic acid 19:649;23:268; 26:966,991 microbial transformation of 26:991 Xanthyleton 23:338,342 Xenia 25:690 Xenicane 25:690 Xenobiotic metabolites 7:103 Xenobiotics 9:582,583;26:755;27:749 and cooxidation 9:582,583 oxidation of 27:749 Xenochemicals 18:680,681 Xenocoumacins 15:381-472 biological activities of 15:408-412 from Xenorhabdus nematophilus 15:389 introduction of 15:381,382 isolation of 15:388-392 structural studies of 15:392-408 Xenopus 25:294 Xenopus laevis 8:435;27:805 [3-thymosin from 8:435 thymosin [~4• from 8:435 Xenopus oocyte 15:451 Xenopus-derived 27:807 Xenorhabdus nematophilus 15:389 xenocoumacins from 15:389 Xenorhabdus spp. 15:381 Xerocosmus 29:271 Xeromphis spinosa 7:427 Xestaspongins 25:732 Xestin AB 18:718,719 Xestoaminol A 26:487 Xestocylamine activity 24:573 inhibition of protein kinase C 24:573 Xestomycin 25:826 Xestoquinol 17:62 total synthesis of 17:62 CD and absolute stereochemistry of 17:66 Xestoquinolide B 25:862;677 protein kinase activity of 28:677 Xestoquinone 17:62;25:861 total synthesis of 17:62
863 CD and absolute stereochemistry of 17:66 Xestospongia 25:694 Xestospongia ashmorica 21:262;25:710 [~-carboline alkaloids from 21:254 Xestospongia carbonaria 25:861; 28:677 Xestospongia exigua 15:312;17:33; 21:267 xestospongin A from 21:267 xestospongin B from 21:267 xestospongin C from 21:267 xestospongin D from 21:267 Xestospongia genus 25:861 Xestospongia sapra 15:312;17:33; 28:677 Xestospongia sp. 5:350,353;18:718; 21:260,265,266;25:703,709,710, 769,859,898;26:487 (22R ,23 R)-22,23-methylenecholesterol from 9:37 XHCORRD 9:268,285 Ximenia americana L. 22:535 for convulsions in children 22:535 Ximenia caffi'a 22:535 for epilepsy 22:535 Xindongnin A 15:116 13C-NMR of 15:130 from Rabdosia dawoensis 15:171 from Rabdosia rubescens 15:174 ~H-NMR of 15:123 Xindongnin B 15:119 13C-NMR of 15:133 from Rabdosia rubescens 15:174 IH-NMR of 15:126 Xiphidium 17:372 Xiphimena diversicaudatum 26:460 X-ray absorbance spectroscopy (XAS) 25:359 X-ray absorption fine spectroscopy (EXAFS) 25:338 X-ray analysis 5:474,478,488,494,508, 509,750,754,755 carbonyl]-2-oxazolone 12:423 of (+)-isoconcinndiol 6:26
of (+)-aristoserratine 11:296 of (+)-aristoteline 11:278 of(+)-retigeranic acid A 13:22 of (22R,23,R)-22,23methyenecholesterol from 9:36,37 of 1,1,6,6-tetrachloro-3,4diphenyl hexane 9:86,88 of 11-bromoebenzoate 7:389 of 1-N-(-p-bromobenzoyl) mitomycin A 13:434 of 2,5-benzooxazonine derivatives 6:180,181 of 2,7-benzooxazacycloundecine 6:199 of 5-deoxygoniopypyrone 9:394 of 7-p-bromoanilino-7-demethoxy mitomycin B 13:434 of amphotericin B 6:261 of aureol 9:31 of cyclofriedo-oleanone 7:152 ofdidemnin-B 10:266-268 of diphosphane adamantane 9:528 oferythromycin A 13:156 of glocosporone 9:228 of goniofufurone 9:394 of goniopypyrone 9:394 ofisomitomycin A 13:468 of laurenene 13:19,20 of maytensifolic acid 7:152 of methylamine dehydrogenase 9:582 ofmitomycin A,C 13:334 ofmitomycin B 13:334 ofmitomycin C 13:334 ofN-acetyl muramic acid 6:387 ofnapoleogenin B 7:139 of netzahualcoyon 7:147 of orthosphenic acid 7:147 ofpacifigorgiol 9:254 ofpfaffic acid 7:135 of phaseolinone 6:555 of plumbazeylanone 5:754,755 of pseudobactin 9:539 of reissantioloxide 5:750 ofretigeranic acid B 13:25 of sigmosceptrellins-A-C 9:16 oftetraponerine-8 6:451
864
of thieno analogue 6:195 of trichophylline 9:191 of trunculins-A-B 9:20 of tubulosine 9:401 of villalstonine 13:399 of vitamin D3 9:510 X-ray crystal structure 9:7-9,272,283; 15:213 brominated, nargenicine 17:296 of ascidiacyclamide 4:93 of azadirachtin 9:94,103,105 ofcadlinolide A 9:7-9,272,283 of caudicifolin 9:288 of chromodorolide A 9:4,5 of ent- 13 [S]-hydroxyatis- 16-ene3,14-dione 9:272,273 of novel natural products 9:3-13 ofoxazoline 17:303 ofpiperazinomycin 10:638 of staurosporine 12:367 of taxotere 12:225 of urdamycin A 11:134 of utilin 9:3 of zoanthaminone 9:10,11 X-ray crystallography 21:204,209,213, 224,228,231,430,435,693,694,756, 759,762;24:138 ofsaponins 24:138 X-ray diffraction 6:196 Xuxua 23:657 Xuxuarines El3 30:682,683 13C-NMR spectra of 30:682 IH-NMR spectra of 30:682 CD spectral of 30:683 FAB-MS of 30:683 ROESY of 30:683 Xylanase A 8:349,351 Xylanase B 8:349,351 Xylanases 8:336,349,351,352;25:312 Xylanasic 24:983-993 enzymatic activity 24:983-993 Xylans 26:1156 Xylerithrin 29:298 biosynthesis of 29:298 Xylerythrins 29:293,299 5-O-methylxylerythrin as 29:293 peniophorinin as 29:293 peniosanguin as 29:294 synthesis of 29:299
Xylitol pentaacetate 4:509 synthesis of 4:509 Xylobiose 8:352 Xylocarpin 7:190,191 Xylocarpus grantum 7:190,191,195 Xylocarpus moluccensis 7:176,191,195 xylomollin from 7:185 Xylocarpus sp. 7:176 Xyloccensins A,B,D,F 7:191 D-Xylofuranose 6:359 C3-P bond analog of 6:359 Cs-P bond analogs of 6:365-367, 375 9-[5'deoxy-5'(methylthio)-/3-DXylofuranosyl)adenine 25:829 D-Xylo-hexofuranose 6:365,367,372 Cs-P bond analogs of 6:365,367, 372 Xylomannans 5:290,294 Xylomollin 7:185 from Xylocarpus moluccensis 7:185 Xylopia aethiopica 20:484;21:611 oxoaporphines of 20:483 Xylopia aromatica 21:600 Xylopia longifolia 21:600 Xylopine 21:57 Xylopinine 1:217,218;3:435 synthesis of 1:217,218;3:433 6- O-/3-D-Xylopiranoside 25:224 D-Xylopyranoses 6:366,367 synthesis of 6:366,367 3-O-[3-Xylopyranosides 15:64 D-Xylopyranosyl 15:7 4-S-D-Xylopyranosyl -4-thio-D-xylose 8:336 D-Xylose 6:263,278;7:144,268,270, 275,277,278,299 ;30:452 1,2-O-isopropylidene derivative from 6:269,270 L-Xylose 6:263,278 1,2-O-isopropylidene derivative from 6:269,270 Xylose 7:71,72,181,270,272,273, 275,292,293,299 [3-Xylosidase 7:58,70;8:352;25:210 from Bacillus pumilus 7:270 Xylosidase 7:270
865
3-Xyloside 23:745 [3-D-Xyloside permease 8:352 Xylosides 8:362 synthesis of 8:362 Xylosyl chlorides 8:359-362 [3-Xylosyl- ( 1-->3)-thio gluc o fur ano se thiodisaccharide 8:329 Xylotheca tettensis var. fissistyla 22:535 in convulsions 22:535 Yadanzioside A-G,I-L,N,O 7:378-379, 392 Yadanzioside-A 23:313 Yadanzioside-B 23:312 Yadanzioside-E 23:313 Yadanzioside-F 23:312 Yadanzioside-G 23:288,313 Yadanzioside-L 23:312 Yadanzioside-M 23:313 Yadanzioside-N 23:288,313 Yadanziosides M,P 7:376 Yadanziosides-G,N 7:275,376 YADH 17:482 Yahazunol 15:297 Yakuchinone A and B 17:362 Yakuchinone-A 23:804 Yamada's synthesis 12:203 Yamaguchi conditions 26:1229,1230 of 4-AboA 27:193,203,204,225 Yamaguchi method 11:154,157,158 Yamaguchi reagent 11:157 Yamamoto condensation 12:24 of propargylic titanium reagent 12:2 regioselective 12:24 stereoselective 12:24 Yama-Ninj in 27:429 Yamayomogenin 7:236 Yang et al. 29:210 triptolide synthesis by 29:210 Yangambin 24:741 anti-platelet aggregation activity of 24:741 (+)-Yangambin 26:242,243,264 as PAF-induced inhibitor 26:242 Yarrowia lipolytica (Candida lipolytica) 13:308,312,313 Yarrowinina lipolytica 25:150
Yashabushidiol A 17:359 Yashabushiketodiol 17:359 (-)-Yatein 18:557,566;26:157,192,213, 218;30:569,587,588,590,595 activity against A549 (human lung adenocarcinoma) 30:588 activity against HT-29 (human colon carcinoma) 30:588 activity against KB-16 (human oral epidermal carcinoma) 30:588 activity against P-388 (murine lymphocytic leukemia) 30:588 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 as platelet aggregation inhibitor 30:594 cytotoxic effect of 26:213; 30:589 (+)-Yatein 29:388 steganes synthesis of 29:388 Yatein 5:484-488 cis-Yatein 5:486 trans-Yatein 5:487 Ydiginic acid 14:101 Yeast alcohol dehydrogenase 17:482 Yeast glucans 23:115,113 13C-NMR spectrum of 23:114 structure of 23:113 Yeast glycogen phosphorylase 27:821 Yeast kex 2 protease (Kexin) 25:387, 388,389 Yeast mutant 30:171 fusion of 30:171 Yeast reduction 1:482;13:560 Yeasts 1:689 for asymmetric reduction 1:689 "Yellow pigment" 11:127-129 Yellow rhizomes 23:820 Yenhusomidine 1:204,205 synthesis of 1:204,205 Yenhusomine 1:204,205 Yersinia 4:195 Yessotoxin 17:20;28:653 analogues of 28:653 in diarrhetic shellfish poisoning (DSP) 28:653
866 YH-47522 21:388 Yinghaosu A 26:807 YL-037098 21:391 5-Ylidene- 1,4-dioxalan-4-one intermediate 30:441 (E)-5-Ylidenepyrrol-2-(5H)-one 21:416 y-Ylidene-y-butyrolactone structure 26:363 Ylides 4:554-556 acylation of 4:554-556 YM-47522 21:373,374,391 2-Ynoic acid 21:386 Yohambinine 9:171 (-)-Yohimban 18:384 (-)-allo-Yohimbane 14:267,277,278 from levoglucosenone 14:267, 277,278 synthesis of 14:267,277,278 Yohimbane 2:173,357,377;5:74,127; 11:302,303 ;14:751,765 synthesis of 3:406,407 Yohimbanoid alkaloids 10:688 (+)-Yohimbine 14:566,567 enantioselective synthesis of 14:566,567 from piperdine derivative 14:566,567 (+)-Yohimbine 14:566,567 enantioselective synthesis of 14:566,567 from piperdine derivative 14:566,567 Yohimbines 2:375,377;3:399,403; 8:395 ;21:57,98,108;25:20,29,530 as immunosuppressive drug 25:530 from Corynanthe yohimbe 8:283 lead tetraacetate oxidation 1:158 oxidation of ring C 1:158 synthesis of 3:407-410 Yohimbine precursor 3:435 synthesis of 3:435 Yohimbine-type alkaloids 5:73,74;25:3 Yomogi alcohol 9:530 Yomogiartemin 7:236 Yomogin 7:233;29:87 activity in iNOS assay system 29:87 activity in NO assay system
29:87 systems 29:87 Yoshikawa 29:481 validamine synthesis by 29:481 Yuanhuacine 13:660 Yu-Lin-Wu synthesis 6:14 of (+)-polygodial 6:14 of (-)-polygodial 6:14 Yunganogenin C 25:96 Yunganosides 15:297 Yurenolide 23:341,343 (Z)-zinc (II) enolate 12:166 Zahavin A 29:103 activity in AOS bioassay system 29:103 from marine soft coral 29:103 Zahna africana 21:657 oleanane saponins from 21:657 Zaitev reaction 1:318,517,518 Zalcitabin 24:474,486,488 as anti-viral agent 24:474,486, 488 Zalerion arboricola 22:69,248;23:343 (-)-3-epi-Zaluzanin 14:365 (+)-Zaluzanin C 14:366,367 synthesis of 14:366,367 (+)-Zaluzanin D 14:366 Zamthaxylum americanum 9:402 Zanardi and co-workers 29:473 carbaaldopyranoses synthesis by 29:473 Zanthoxyllum naranjillo 26:799 Zanthoxylum ailanthoides 10:152; 21:378;24:690;26:188;27:167 Zanthoxylum armatum 26:267 Zanthoxylum avicennae DC. 27:159 Zanthoxylum chalybaeum 22:535; 27:160;29:692 Zanthoxylum clavaherculis 24:686,689
Zanthoxylum conspersipunctatum 27:164
Zanthoxylum holtzianum 22:535 in convulsions 22:535
Zanthoxylum integrifolium 27:167 Zanthoxylum liebmannianum 26:450 Zanthoxylum nitidum DC. 27:159, 160,168
867 6-oxoderivative of 27:160
Zanthoxylum punctatum 27:159 Zanthoxylum simulans 22:536;27:863 Zanthoxylum sp. 27:164 Zanthoxylum spinosum 27:170 Zanthoxylum tessmanii 27:159 Zanthoxylum usambarense 27:160 Zanthoxylum xanthoxyloides 21:611 Zaragozic acid A 23:344 Zaragozic acids 21:192,193;23:344; 24:431-433 structures of 24:431-433 Zea luxurians 29:600 Zea mays 27:215 allelopathic interaction of 27:215 Zea mays L. 19:247;23:342;25:671; 27:191,193,215 ;29:594,609 Zearalenone 6:213,214;9:203,204,206; 13:536-543 synthesis of 13:536-543 Zearalenone glycoside 13:539 Zearalenone-4-sulfate 13:539 Zeatin 4:227 Zeaxanthin 7:320,330,336,343,349, 351,358,363 ;6:139;20:573 ;21:305; 26:299,300,306;27:321 ;30:520,521, 523 13C-NMR of 7:342,345,346 ~H-NMR of 7:347,348 5,6-epoxidation of 30:521 absolute configuration of 7:360 allenic carotenoids from 6:139 C-3 hydroxylation of 7:359-361 from Physalis alkekengi 7:360 functions of 30:523 in biosynthesis 6:139;27:321 (3 R,3 R ')-Zeaxanthin 6:136,149 Zeaxanthin disulphate 30:528 from zeaxanthin 30:528 synthesis of 30:528 Zederol 23:827 Zedoarondiol 23:825 Zefbetaine 26:610,616,617 iso-Zefbetaine 26:616 Zelus leucogrammus 2:299,301 Zemplin conditions 6:409 Zemplin de-O-acetylation 12:348 Zemplin O-deacetylation 6:412 Zemplin reaction 6:411
Zemplin transesterification method 21:163 Z-Enediones 16:648 Z-Enolate 16:661 Zephyranthes flava 26:616 Zeralenone 8:176,177 from 0~-iodoalkyl-2phenylthiomethyl-4,6dimethoxybenzoate synthesis of 8:176,177 Zerumbone 23:836;29:91 activity in EBV assay system 29:91 activity in colon-1 assay system 29:91 activity in AOS assay system 29:91 activity in APO assay system 29:91 activity in COX assay system 29:91 activity in iNOS assay system 29:91 activity in TNFc~ assay system 29:91 Zerumin A 23:809 Zerumin B 23:809 Zeuxis siquizorensis 18:724 Zeylandiol 5:744,746;7:147,148 Zeylanol 5:744,745;7:147,148 Zeylanone 2:212-215;5:754,755 Zeylanonol 5:744-747;7:147,148 Zeylasterone 5:744-747;7:147-150; 23:711;30:674,676 structure of 30:676 Zeylasterone-2,3-dimethyl ehter 18:765 (+)-Zeylenol 23:841 Z-homoallylalcohol 30:41 Lindlar's catalyst 30:41 Zidovudine 23:97;24:474,486,487 as anti-viral agent 24:474,486, 487 Ziegler/Brown/Robin 29:391 steganes synthesis by 29:391 Zimmerman-Traxler transition state 4:445 Zinc (II) chloride 12:172,173 1,4-dehydro-[~-lactam from
868
12:172,173 with 4-acetoxy-13-1actam 12:172, 173 Zinc (II) iodide 12:164 Zinc amalgam 30:222 Zinc borohydride 1:261;4:348 reduction with 1:261;4:348 Zinc bound alkoxide 17:481 Zinc clathridine 17:18 Zinc mediated coupling 1:264,265 Zinc-copper couple 4:424 in deoxygenation 4:424 in reductive elimination 4:165 Zinc-dust 12:166 in deoxygenation 4:424 Zincke's salt 19:38 Zincophorin 3:276,277 synthesis of 3:276,277 Zingerone 9:321;23:804 Zingiber 17:365;26:905;23:843 Zingiber amaricans 24:274 Zingiber cassumunar 23:815,842 Zingiber off~cinale 9:321;17:365; 23:845 ;24:273,900;26:474,902 sesquiterpene from 8:52 Zingiber off~cinarum 17:378 Zingiber ottensi 22:536 for convulsions 22:536 Zingiber zerumbest 29:91 Zingiberaceae 23:797-865 phytochemistry of 23:797-865 (-)-Zingiberene 8:45 from R-(+)-citronellal 8:45 synthesis of 8:45 Zinnia elegans 25:377;27:765 Zinnolide 4:598 Zinziber cassumar 17:365 Zinziber officinale 17:365 Zirconium (IV) enolate 12:168 Zirconium derivatives 9:453 as fluorescence-inducing reagent 9:453 Zirconium enolate 3:249;13:506 ofphenylthio ester 13:506 [2,3]-Wittig rearrangement of 3:249 Z-Isomers 30:441 by transesterification 30:441 Zizaane sesquiterpenoids 16:125
ent-Zizaenes 15:251 Zizaenes 15:273 Zizane 15:227
(-)-2-epi-Zizanoic acid 4:674
(+)-Zizanoic acid 4:674;8:425 Ziziphin 18:671;27:42,47-49 structure of 27:49 Ziziphusjujuba P. Miller 15:36;18:671; 21:674;27:42,47,48 jujuba saponin II from 27:41 jujuboside B from 27:41 saponin I-III from 27:42 ziziphin from 27:41 Ziziphus mauritiana 20:507 Zizyphus 27:42,49 Zizyphus spinachristi 21:666 christinin A from 21:666 Zn(II) protoporpyhyrin (IX) 25:335 Zoanthaminone 9:10,11 biogensis of 9:10 X-ray crystal structure of 9:10,11 Zoanthid 9:10;25:711 Zoanthus sp. 25:711;28:646 sphingolipid hariamide from 28:646 zoanthid A from 28:646 Zoapatanol 10:210 total synthesis of 10:210 Zoapatline 19:389 isolation of 19:389 (-)-Zonarene 6:15 by transannular ene cyclisation 6:15 from Dictyopteris zonaroides 6:15 from (-)-piperitone 6:15 synthesis of 6:15,16 Williams enantioselective synthesis of 6:15 Zonaric acid 15:297 Zonarii 17:198 Zonarol 6:18;9:40;15:296,320 from Dictyopteris undulata 6:17 Rau synthesis of 6:17 synthesis of 6:17,18 Welch synthesis of 6:17 Zonarone 15:296
869
Zonotrichia leucophyrys 5:837
hemoglobin components of 5:837 Zoobotryon verticillatum 17:85 Zooecdysteroids 29:10 biochemical roles of 29:10 classification of 29:10 20,26-dihydroxyecdysone as 29:10 hydroxyecdysonoic acid as 29:10 Zoogloea ramigera 1:689,690 Zoospore attractants 22:482-502 Zooxanthellae 9:47;21:272 Zuurbergenin 7:236 Zwitterion 6:336 Zwitterionic anthocyanins 5:664 Zwitterionic aza-Claisen rearrangement 16:466 Zwitterionic aza-Claisen rearrangement 16:466 Zygadenine 21:73 Zygomycetes 9:202,203; 18:814 glycosphingolipids from 18:806 Zygomycota 22:246 ascomycetes from 22:246 Zygomycotina 9:202 Zygophyldsides A,B 9:59,60 Zygophyllum propinquum 9:59-62 saponins from 9:59-62 Zygosporin E 13:146,147 synthesis of 13:146,147 Zygosporium masonii 15:356 Zymogen activation 25:391 Zymosan 26:342;30:778 from yeast 30:778 Zymosan-activated macrophages 25:274 Zyzzafuliginosa 25:708,760,770 Zyzza massalis 25:760,898 Zyzzya cf. marasailis 25:790,824; 28:686;29:253 discorhabdin A from 28:686 makaluvamine F from 28:686
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871
CUMULATIVE ORGANIC SYNTHESIS INDEX VOLUMES 1-30
Abietic acid 29:188 pisiferic acid synthesis from 29:188 ABA 27:341,354 of l'-Methyl ether 27:341 photoisomerization of 27:354 Abnormal Beckmann rearrangement 16:133 Abramov reaction 6:353 Abscisic acid 27:322,335,337,388 conformations of 27:335 metabolic inactivation of 27:322 NOE experiment of 27:338 (-)-Abscisic acid 27:346 formation of 27:346 (+)-Abscisic acid 27:346 formation of 27:346 Abscisic acid ring 27:336,338 interconversion of 27:336 Abscisic acid-GE 27:354 hydrolysis of 27:354 Abscisic aldehyde 27:321 in biosynthesis 27:321 Acetalization 1:584 trans-Acetalization 4:325,326,331,338, 339,495 Acetolysis 30:489 Acetylation 19:480 of syn alcohol 19:480 13-Acetylation procedure 10:447 for acetomycin synthesis 10:447 stereoselective 10:447 Acetylation reaction 23:172 of tobagolide 23:172 2-Acetylbutyrolactone 8:284,285 (___)-N-Acetylcolchinol 29:376 allocolchicinoids total synthesis of 29:376 Acetylenation 1:611,612 of acetals diastereoselective 1:611,612 Acetylenic oxy-Cope rearrangement 8:250
N-Acetylneuraminic acid (Neu5Ac) 30:420,425 synthesis of 30:425 Acetylsalicylic acid 26:162 synthetic derivatives of 26:162 Acid-catalysed aldol condensation 30:217 of phenylacetone 30:217 Acid-catalysed cyclisation 30:217 of 1-benzyl- 1,2,3,4-tetrahydro isoquinolines 30:217 Acid-catalysed methanolysis 30:44 Acid-catalysed rearrangement 6:115; 23:487,515 of aglycones 23:487,515 of (+)-endo-3-bromocamphore 16:147 of spiro cyclic lactone 16:225 Acid-labile protecting groups 30:441 5-Active peptide analogues 30:801 synthesis of 30:801 1 lo~-Acyl turkesterone 29:19 as synthetic ecdysteroid analogues 29:19 Acylation 30:627 of hexaenal 6:264,267 selective 6:283,284 with N,N-diisopropylcarbamoyl chloride 10:15 intramolecular 16:18 with Cbz-L-alanine 16:18 with ethylchloroformate 16:19 N-Acylation 16:22 with Cbz-L-alanine 16:22 Acyliminium ion cyclization 1:244; 12:305,320,335 N-Acyliminium ion cyclization 11:290 intramolecular 11:284,285 N-Acyliminium ion-polyene cyclization 12:464 N-Acyliminium ion-vinylsilane cyclization 12:453 l-Acylindoles photoisomerisation 1:51
872 Acylnitroso Diels-Alder reaction 1:386,4:606 Acylnitrosocycloaddition 19:355 1,4-Addition 24:6 of hydride 24:6 syn Addition 8:296-298,304 Addition reaction 12:35-62 of chiral vinyllithium compounds 12:35-62 to t~-methyl-substituted aldehyde 12:35-62 1,4-Addition reaction 14:696,697 Addition-elimination mechanism 11:185,187 for 5-enolpyruvylshikimate 3phosphate synthase 11:185,187 Adenosine 30:384 conversion of 30:384 Aflatoxin M2 14:651-657 Norrish type II reaction 14:651-657 (_+)-Africanol Claisen rearrangement 6:51 Agelasidine A 28:670 synthesis of 28:670 Agelasidine B 28:670 synthesis of 28:670 Aglycone 23:487,515;27:667 anomeric configurations in 27:667 acid-catalysed rearrangement of 23:515 Agrofoglio 29:461 carbafuranose synthesis by 29:461 A1-Abed and Seepersaud 29:460 carbaketofuranose synthesis by 29:460 Alcohol dehydrogenase 17:479 Alcohol inversion 1:456,457,459 Alcohol protection 1:558 as MEM ether 1:558 Aldoheptofuranoses asymmetric quaternization 10:428-432 Johnson-Claisen rearrangement in 10:432-436 Aldol condensation 13:448,468;24:728, 729;30:213,215,423,433,472 acid-catalyzed 16:216,220
aldolase-catalyzed stereocontrolled 30:423 asymmetric induction in 4:328,329 base-catalyzed 16:220 by aromatisation 30:213 by cyclisation 30:213 chelation controlled 10:286 crossed 11:296,297 diastereoselective 4:328,329; 12:15,16 enzyme assisted 30:472 intermolecular 10:182,183, 318-320;11:113,115 internal 1:363-365 intramolecular 10:303,306,318, 329,330;16:141,216,221,228, 259,260 of arylethanals 30:215 of furanone 12:13 of silyl enol ether/acetone 11:296,297 stannic chloride catalysed 4:328,329 TIC14 catalysed 1:537,538 and [3-elimination 12:13 anti-Aldol condensation 30:435 Aldol condensation-intramolecular cyclisation 30:217 Aldol coupling reactions 11:435-439 Aldol cyclization 6:49,50;24:201 2-amino alcohol by 12:411,414 asymmetric 4:327 chiral acetals in 4:329 chiral synthons for 4:491 of ct-sulfinylesters 4:491-494 of aldehyde 12:174,411,414 of ascorbic acid 4:699-705 in (+)-spatol synthesis 6:40,41 stereoselective 12:154 with enolsilyl ether 12:174 with isonitrile 12:411,414 with N-acylimine 12:160 Aldol reactions 13:206;30:438 from alditols 30:438-445 intramolecular McMurry approach 13:602 Aldol stereoselectivity 12:72
873 Aldol syntheses 30:434 from acyclic aldoses 30:434-438 Aldol type addition 16:656 Aldol type condensation 8:426,427 of aldehydes 8:426,427 with 2-trimethylsiloxy-3methylfuran 8:426,427 Aldolization 6:7,9,10,17 Aldol-type cyclization reaction 29:436 in alkaloids synthesis 29:436 Aldol-type reaction 12:36 stereocontrolled 12:36 stereoselective 12:166 Aldose aldehydes 30:446 elongation of 30:446 Alizarin 26:635-637,642 synthesis of 26:635-637,642 Alkaline hydrolysis 27:671 Alkaloid 223A 29:439 C-6 epimer synthesis in 29:442 conjugate addition reaction in 29:441 of dart-poison frog alkaloid 2071 29:444 stereochemistry of 29:444 stereoselectivity of 29:443 stereoelectronically favored axial attach in 29:443 Alkanol 7:231 asymmetric hydration of alkene 13:451 asymmetric hydroboration of alkene 13:451,452 oxyamination of alkene 12:411, 413 photochemical additions to alkene 1:642 A3'4Alkene 12:22 o-Alkenyl dehydroglycosides 3:245 6-Alkenyl-4-oxapyran-2-ones 10:340 by enolate Claisen rearrangement 10:340 Claisen rearrangement of 3:245 hydroboration of cis-alkenes 8:471,472 thermolytic cyclization of 6:429 Alkylation 10:408,409;14:491-499; 24:2,10,11,14,22,23,25,201, 210,749;30:627
asymmetric 11:367 base (LDA) mediated 10:408,409 diastereoselective 14:491-499 enantioselective 10:412 in basic media 4:389-391 intramolecular 16:125;19:486 of (-)-arctigenin 24:749 of (S)-o~-terpinylamine 11:283 of 1,5-acetyl- 1-thiohex-2enopyranosides 10:342 of 1-benzyl-2,6-dicyanopiperidine 6:433 of l-phenyl-l-methyl 6,7 selenol-ethyllithium 8:6,7 of 2-acetoxy-5,6-dihydro-2Hpyrans 10:342 of acetals 1:613-616 of benzyllithium 8:6 of carbanion 8:176 of carvone 10:408,409 ofchiral acetals 12:489-493 of cyanohydrin 8:16 of cyanohydrin ethers 8:177-179, 183 of dianion 11:284,285 of dimethyl malonate 8:185,186 ofdioxolane enolates 1:644 of (-)-dimethyl matairesinol 24:749 of (-)-enterolactone 24:749 of (-)-hinokinin 24:749 of (-)-kusunokinin 24:749 of (-)-yatein 24:749 of FAMSO 6:313 of fluoromalonate 13:82 of methylmalonate 13:79 of MT-sulfone 6:334 of N-nitrosopyrrolidine 6:439,441 of silver cyanides 12:113 of sulfur stabilized carbanion 8:16 of trans-2,5-bis (methoxymethoxymethyl) pyrrolidine 10:412 of w-haloalkylphenylthioacetate 8:176 of t~-methyl-phenylacetic acid 10:412
874
of ~-phenyl-y-lactone 10:410, 411 of ~-ketoester 8:181,191 palladium-mediated 16:422 regioselective 10:342 stereoselective 10:342,410,411; 11:284,285 synthesis of 3:166,167 TIC14 catalysed 1:615 via sequential dianion generation 16:371 with l-TMS-2-pentyne 11:284, 285 with 2,5-dibromo-2-methyl pentane 8:6,7 with 3-butynyl p-toluene sulphonate 14:559 with allylic halide 8:178 with benzyloxymethyl chloride 6:561 with di-t-butyl dicarbonate 14:559 with House procedure 10:308, 309 with indole-protected tryptophyl bromide 11:283 with organometallic reagents 1:613-616 S -Alkylation 8:214;13:145 intramolecular 13:145 7-Alkylation 6:76,77 in (+)-sinularene synthesis 6:76,77 N-Alkylation 16:99,104 reductive 16:99,104 with D-glyceraldehyde 16:99,104 with L-glyceraldehyde 16:99 O-Alkylation 6:385 of glucopyranoside 6:388 of N-substituted amides 10:215 of potassium kojate 12:261 of w-haloalcohol 8:195 of ~-D-glucopyranoside 6:385 3-Alkylpiperidine alkaloids 24:575-579, 581-584,588-605,611-670
biogenesis of 24:662-670 total synthesis of 24:588-605, 656 Alkynyl Grignard reagents 6:448 reaction with 1-methoxycarbonyl pyridinium chloride 6:448 reaction with 2-methylpyridinium salts 6:429 Allene epoxide 8:36 rearrangement of 8:36 Allenylindium 30:19 Allenylzinc reagents 30:19 Alliin 23:341,457,458,461 formation of 23:461 from S-allyl ~/-glutamylcysteine 23:461 Allocolchicine analogues 29:378 allocolchicinoids total synthesis of 29:378 Allocolchicinoid synthesis 29:364 for biological screening 29:366 from colchicine 29:364 role of colchicine tropolone ring in 29:364 Schmidt rearrangement in 29:365 to prodrug of N-acetylcolchinol 29:366 Allocolchicinoids 29:356 semi-synthetic analogues of 29:359 synthetic analogues of 29:359 Allocolchicinoids total synthesis 29:373,379 by Banwell 29:377,378 by Boy~ and Brossi 29:378 by Cook 29:375 by Rapoport 29:374 by Wulff 29:379 intramolecular oxidative biaryl coupling in 29:376 of (-)-N-acetylcolchinol methyl ether 29:375 of (+_)-colchinol methyl ether 29:374 of (+_)-jerusalemine 29:377 of (_+)-N-acetylcolchinol 29:376 of allocolchicine analogues 29:378
875 of colchinol analogue 29378 o f positional isomers 29:378 phenanthrene ring enlargement i n 29:374 stereocontrolled approach to 29:379 Allyl acetates 4:2 1,49 isomerization of 4:49 allylation of 4:2 I Allyl ether 1:453 isomerization to vinyl ether 1:453 Allyl glycidyl ether 10:588,589 cyclimtion of' 10588,589 oxetane ring formation by 10588,589 a-Ally1 glycosides 10:348 by miti SN' displacement 10:348 from D-glucal triacctate 10:4I9 Allyl isocyanidc 12:1 I3 from ally1 iodide 12: I I3 from silver cyanide 12: 1 I3 Allyl mangenesc reagent 4:34,344 n-Ally1 palladium complcx 4500; 10:2 I4,2 15 n,-AIlyI Pd alkylation 10:10- 13 intramolecular 10:I0- I 3 Allyl sulfones 3:23 addition to enoncs 3:23 Allyl sulfoxide anions 3:2 I ,22,435 addition to cnones 3:2 I ,22 synthesis of 3:435 Allylamincs 12:411,414 2-amino alcohol by 12:4I 1,4I4 cyclocarbaniations 12:4I I ,4 14 Allylation 1:604-610;24:198 diastereoselective 1:604-610 of 2-acetylcyclohexanone 10:4 I 2 of FAMSO 6:3 I5,3 I6 with ally1 acetate 10:412 Allylation reaction 12:484,14:474; 30:452 stereochemical outcome of 30:452 O-Allylation-Claisen rearrangement 12:269 Allylboration 8:477,478
Allylboronate 1:3 I 1,312 stereoselective addition to glyceraldehyde 1:3I I ,3 I2 n-Allylcation complex 3:82,83 Allylcerium 8:24 Allylchromium reagent 30:24 Allylchromium species 3:81 coupling with carbonyls 3:8 1 medium ring compounds from 3:sI a-Allylglucosides 3:2 14,2IS synthesis of 3:2 14,215 Allylic polyprenols 8:66,67,72 synthesis of 8:66,67,72 Allylic acetoxylation 16:420 Allylic alcohol 12:46,47 allylic aldehyde from 12:46,47 amides from 14:722,723 asymmetric cyclopropanation of 14:490,491 biomimetic cycliLation of 14:717-720 by Claisen rearrangement 14:722,723 epoxidation of 10:39,40 2,3-epoxy alcohol from 14570 from (R,R)-2,3-butanediol 14:490 from acetylenic ketone 11:424 from r>-glucose 10:428-438 from diniethyl -tartrate 11:267,268 Johnson-Claisen rearrangement of 10:428-438 mesylation of 4: 172,I73 one-carbon homologation 3:238 oxidation of 12:46,47,16:594 preparation of 11:424 sharpless epoxidation of 14:570 transformation of 3020 with MnOz 12:46,47 with VO (acac)'-TBHP 10:39,40 Z-Allylic alcohols 4:203 cis-hydroxylation of 4:203 Allylic bromination 6:207 Allylic carbocation 4: 172- I74 asymmetric epoxidation of 4: 172-174
876 Allylic carboxyl group 3:487 phytochemical removal of 3:487 Allylic C-O bond cleavage 1:557,558 with dissolving lithium/amine reduction 1:557,558 Allylic displacement reactions 16:397 palladium catalyzed 16:397 Allylic ethers 4:116 hydroboration of 4:116 Allylic glycolate esters 10:437 Ireland-Claisen rearrangement of 10:437 Allylic hydroxylation 1:535;6:200,201 with SeO2/tert-butylhydroperoxide 1:535 Allylic oxidation 3:448;6:126,159,162; 8:197,198;11:11,40,41 ;12:311; 16:420,669;24:36,37,56-58, 72-74,79,89,90,179,180,186,187 of perezinone 5:722 with Collins reagent 11:83,84 with manganese dioxide 11:356, 357 with SeO2 1:549,550 Allylic radicals 4:525 reductive elimination of 4:525 Allylic rearrangement 4:556;6:159; 14:191;16:305,617,669 Allylic sulfoxide rearrangement 1:560, 564 Allylic ~-hydroxysulfoxides 4:503,504 stereoselective hydroxylation 4:503, 504 Z-Allylic ~-ketosulfoxides 4:509,510 synthesis of 4:509,510 Allylmetal additions 8:16 cz-Allyloxy anions 3:248-250 [2,3]-Wittig rearrangement of 3:248-250 Allylsilane 14:482 Allylstannane 1:247,256,312,313; 10:17-25 Allyltin derivatives 11:442,443 nucleophilic addition by 11:442, 443 Allyltitanium phosphorus reagent 30:17 Allysilane 1:314
Alpinolide 23:813 synthesis of 23:813 Aluminium hydride 3:474 selective reduction with 3:474 Amadori rearrangement 18:680 Amalgam procedure 14:746 Amide cyclisation 4:546 Amidoalkylation 10:108 intramolecular 10:108 Amidoalkylation reagents (Nacyliminium ions) 13:473-518 Amidocarbonylation 16:408 Amidocyclization 1:382 Amination 6:429;16:438 intramolecular 6:429;16:438 Amines 6:429 formation from ketones 6:429 photosensitized oxidation of 16:604 reductive animation of 6:429 ~z-Amino acid 12:115,435-438 as chiral building blocks 1:678-684 by hetero Diels-Alder adducts 12:435,436 conversion to amino sugars 4:111-156 synthesis of 12:435-438 Amino acid 16:395-414,604 as chiral synthons 4:625 by c~-halo boronic ester 11:417-420 photooxidation of 16:604 synthesis of 11:417-420, 13:507-516,16:395-414 L-allo-c~-Amino acid 11:460,461 synthesis of 11:460,461 ~-Amino acids 12:158,159 by hetero-Diels Alder reaction 12:158,159 cyclization by UGl-reaction 12:116 cyclization of 12:115,116 ~-lactams from 12:115 synthesis of 12:155,158,159 c~-Amino acids/esters 1:331-338 conversion to azomethine ylides 1:331-338
877 decarboxylation of 1:331-336, 337 imines from 1:33 I Amino acylase 1:678-680 for synthesis of a-amino acids 1:678-680 2-Amino alcohols 12:4 1 1,414 by aldol reaction 12:41 1,414 by cyclocarbamation 12:4 I I ,4 13 by electrophilic addition 12:41 1, 414 by Michael reaction 12:4 1 1,4I3 by nucleophilic addition 12:41 1, 4 1 3,4 14 by oxyaminations 12:41 I ,4 I4 by reduction 12:41 1,414 by ring-opening of oxirane 12:41 1,413 from 2-oxazolone 12:4 I 1-444 synthesis of 12:41 1-444 a-Amino aldehydes 12:4 I I ,4 14 2-amino alcohol by 12:4 I I ,4 I4 in [4+2] cycloaddition 4: I 1 1 in Diels-Alder reaction 4: I20 metalloorganic addition to 4: 124 N,N-diprotected 4: I24 nucleophilic addition of 12:4 I I , 414 preparation of 4: I I3,l 14 N, O-protected 4: 130 Amino carbonylation 14:568 intramolecular 14568 palladium (2') catalyzed 14568 a-Amino ketones 12:4 1 1,414 2-amino alcohol by 12:41 1,414 reduction of 12:41 1,414 steroid-pyrazine dimers via 18:885-887 Amino sugars 4: 1 1 S- 1 18 synthesis from glycine 4:l 15-1 18 synthesis of 13:190-207 3-Amino-3-deoxynucleosides 4:240 synthesis of 4:240 3-Amino-3-deoxysugars 4: I50 synthesis of 4: I SO 6-Amino-6-deoxysugars 4: 1 1 I , 127 from a-amino acids 4: 1 1 I , 127
6-Amino-6-deoxyuloses 4: 124 synthesis of 4: 124
S-Amino-7-methoxy-2,2-dimethylchroman 13:358,359 synthesis of 13:358,359
(L-a-Aminoadipo1y)-L-cysteinyl-Dvaline 6-(LLD ACV) 11:2 I 1-2 13 cephalosporin C from 11:211-213 penicillins from 11:2 1 1-2 13 Amino alcohol 11:298,299 benzyl-protected 11:298,299 with aldehyde 11:298,299 5'-Aminoalkyl oligonucleotides 4:294, 29s synthesis of 4:294,295 4P-Aminoaniline 26: 162 synthetic derivatives of 26: 162 2-Aminobenzothiazole 26: 162 synthetic derivatives of 26: 162 Aminocarbafuranoses 29:462 as building blocks 29:462 diversity-oriented synthesis of 29:463 in structure-based drug discovery 29:464 Aminodeoxyhexosyl-purines 4:238-248 synthesis of 4:238-248 Aminodeoxyhexosyl-pyrimidines 4~238-248 synthesis of 4:238-248 Aminohexose derivatives 1:25-27 synthesis of 1:25-27 Aminolysis 12:279 intramolecular 12:279 of disaccharide lactone 6:407 of MurNAc &lactones 6:393 a-Aminonitriles 14:7 16-718 formation of 14:7 16-7 I8 via Polonovski reaction 1417 16-718 2-Aminonucleosides 4:238 fusion reactions for 4:238 synthesis of 4:238,239 4-Aminooctanal diethyl acetal 6:445,447 condensation of 6:445,447 with diethyl-3-oxo-glutarate
878 6:445,447 with ethanal 6:445,447 5-Aminooligonucleotides 4:294-292 synthesis of 4:294-292 7-Amino-substituted Neu5Ac derivatives 30:426 synthesis of 30:426 via azido derivative 30:426 L-~z-Aminouronic acid 11:459,460 synthesis of 11:459,460 Aminyl radical heterocyclization 1:292 of chloramines 1:292 Ammonolysis 16:97,98 with ammoniacal methanol 16:97,98 Amphibian alkaloids 29:433 synthesis of 29:433 or linoleate (c~-amyrin cis-9,cis12-octadecadienoic acid ester) 29:583 synthesized from c~-amyrin 29:583 c~-Amyrin palmitate (cz-amyrin hexadecanoic acid ester) 29:583 synthesis from ~z-amyrin 29:583 Anacardic acid 11 (Z)-diene 30:144 synthesis of 30:144 Anacardic acid 8(E)-monoene 30:143 by trans elimination reaction 30:143 Anacardic acid 8(Z)-diene 30:144 synthesis of 30:144 Anacardic acids 30:147-148 synthesis of 30:147-148 Analogs 27:336-337 conformational property of 27:337 Angelaud and Landais 29:467 carbaaldopyranoses synthesis by 29:467 1,2-Anhydro-3,4:5,6-di-O-isopropylidene-D-mannitol 30:439 reaction of 30:439 Anion mediated alkylation 8:229 of difunctional acyclic terpenoids 8:229 [3,3]Anion radicals 30:549 dimerisation of 30:549
Anionic oxy-Claisen 12:93 Anionic oxy-Cope rearrangement 3:77,78 eight-membered rings by 3:77,78 Anionic pinacol rearrangement 14:360 Annelation 19:227 of resorcinol 19:227 of substituted phenol 19:227 regiospecific 19:227 Annelation reaction 14:694,695 Annulation 6:5 by Simmons-Smith reaction 6:5 intramolecular 10:407 of 1 methyl-2-tetralone 14:670,671 of cz-diazo-[3-keto ester 10:407 of cyclohexane ring system 6:5,6,29,30 of cyclopentane ring system 6:6-8,30,31 of enolate 10:414,415 of methylenecyclohexane 6:21, 22,53,54 ofpiperidone derivative 14:734 Rh (II)-mediated 10:407 Robinson annulation 6:17-21, 29,30 with 3-methylsilyl-3-butene-2one 10:414,415 [2+3]-Annulation 3:7 annulation methods 3:7 for five-membered rings 3:7 of aldehydes 3:5-58 triquinane synthesis by 3:47,48 [4+l]-Annulation 3:40-45 triquinane synthesis by 3:40-45 [4+4]-Annulation 3:78 Danheiser version 3:78 for 8-membered ring synthesis 3:78-79 intermolecular 3:78 nickel catalysed intramolecular 3:78 Anodic methoxylation 13:485,494 Anodic oxidation 7:161,163;8:159172;13:474,475,479 of ~-N-acetyl-e-N-tosy-L-lysine methyl ester 12:309,310
879 Anomeric configurations 27:469,667 in aglycone 27:667 Anomeric deprotection 6:413-416 of disaccharide dipeptides 6:413-416 Ansamycins 23:79 biosynthesis of 23:79 Antiallergic drugs 29:300 synthesis of 29:300 Aopinolide 23:813 synthesis of 23:813 Arabinose 30:433 reaction of 30:433 L-Arabinose 30:452 allylation of 30:452 Arcyriaoxocin A 29:227 synthetic routes to 29:227 Arene carbene 3:324,325 Arene-metal rt-complexes 20:310-312 Arene-olefin metaphotocycloaddition 3:14 Arenes 27:749,754 hydroxylation of 27:749,754 microbial oxidation of 18:430-432 Arndt-Eistert homologation 1:237; 13:116 Arndt-Eistert reaction 13:79,93 Aromatic amines 27:749 oxy-functionalization of 27:749 Aromatic compounds 6:509 oxidation of 6:509 Aromatic phosphoramidates 14:286 Aromatization 7:360-363;11:114-119; 27:782 of N-heterocyclic ring 27:782 Aryl C-glycosides 10:362,363 from ribofuranosyl chloride 10:362,363 Aryl methyl ketone 14:473 chiral acetal of 14:473 asymmetric cyanation of 14:473 Aryl [3-C-glycosides 10:377 by condensation with tribenzyloxy benzene 10:377 by Lewis acid assisted condensation of aryl ether 10:375
2-Arylbenzofuran synthesis 30:223 from benzylalcohols 30:223 Aryl-C-glycosides 11:139-142 by condensation 11:139-142 via polyketides 11:139-142 synthesis of 11:139-142 Arylethanals 30:214 acid treatment of 30:214 aldol condensation of 215 2-phenylnaphthalene from 30:214 1,2,9,10-tetrahydro- 1,9-epoxy dibenzo[a,e]cyclooctenes (Kagan's ether) from 30:214 Arylethanoid derivatives 30:213 reaction of 30:213 N-(Arylidene) benzyl amines 1:343 2-azaallyl anions from 1:343 isomerization of 1:343 Aryllactic acid 30:216 decomposition of 30:216 Arylnapthalene derivatives 24:762-775 synthesis of 24:761,766 Arylpropanoid 30:213 reaction of 30:213 Arynes 3:418-421,422-454 generation of 3:418-421,422-454 nucleophilic additions of 3:418, 421-437 Ascocorynin 29:296 biosynthesis of 29:296 synthesis of 29:299 Asinger condensation 12:127,129 Astaxanthin 30:518,520,533,538,543 course of formation of 30:543 radicals cations of 30:538 Asymmetric cyclization 10:611,631633 Asymmetric [3+2] dipolar cycloaddition 13:500 Asymmetric 1,3-dipolar cycloaddition 1:371-375 Asymmetric additions 4:332 to prochiral carbonyl groups 4:332 to prochiral naphthalene rings 4:332 Asymmetric aldol condensation 12:162; 13:63
880
Asymmetric aldol methodology 21:438 Asymmetric alkylation 10:411 of methylmalonic acid 10:411 of (-)-phenylmenthyl ester 10:411 Asymmetric allylboration 8:477,478 Asymmetric aza-annulation reaction 18:378,379 Asymmetric bromolactonization 4:338, 339 with acetals from tartaric amides 4:338,339 with N-bromoacetamide 4:338, 339 with chiral acetals 4:338,339 with unsaturated (S)-proline amides 4:336,337 Asymmetric carbocyclization 6:62,63 in (-)-2R,6S, 8S,9S)-2,8-dibromo9- hydroxy-~-chamigrene synthesis 6:62,63 Asymmetric catalysts 17:323 hydrogenation of 17:323 synthesis of 17:479 Asymmetric cyclization 14:506,507 biomimetic 14:506,507 of chiral acetal 14:506,507 Asymmetric cyclopropanation 14:488 with methyl carbenoid 14:488 Asymmetric Diels-Alder reaction 8:139-157 at chiral auxiliaries 4:607 in prostaglandin synthesis 4:607 in tetramycin synthesis 4:607 using chiral boron reagent 4:609 in [3-santalene synthesis 4:607 Asymmetric Diels-Alder technology 13:602 Asymmetric dihyroxylation 11:60; 19:269-270,274,278,284 Asymmetric dimethylation 10:412-415 Asymmetric epoxidation 4:172-174; 10:561;12:323 of (+)-N-benzyloxycarbonyl-3hydroxy-4-of allylic alcohols 4:172-174;10:561 ;12;323
of pentenylamine 12:281 of swainsonine 10:561 Asymmetric esterification 9:25 Asymmetric hydration 13:71 of alkenes 13:71 Asymmetric hydroboration 8:473,474, 478;13:71,72 Asymmetric hydrogenation 12:162; 16:411 ;24:749 BINAP-Ru-catalyzed 4:439 of 13-keto esters 4:439 Asymmetric hydrolysis 1:684,685 by esterases 1:684,685 by lipases 1:684,685 of N-acetyl t~-amino acids 1:678,679 Asymmetric hydrosilylation 13:72 intramolecular 13:72 Asymmetric hydroxylation 9:572 of pentadienols 9:572 1,4-Asymmetric induction 4:203,495 Cram's cyclic model of 4:203, 495 in (-)-piperitone 6:15 in aza-annulation reaction 18:373-386 in dienolate addition 3:47 in diyl trapping 3:20 in Ireland-Claisen rearrangement 3:237 reversion using sulfoxides 4:511 self-immolative 3:237 with chiral auxiliaries 4:499-517 Asymmetric induction 10:412;12:153, 156;14:471,507,508,524,553 1,2-Asymmetric induction 11:231-238 1,4-Asymmetric induction 12:156 1,5-Asymmetric induction 14:499 1,3-Asymmetric induction 14:529,552 1,6-Asymmetric induction 14:530 Asymmetric ketoester cyclization 4:328-330 Asymmetric metallation 14:511 of chiral arylaldehyde acetal chromium tricarbonyl complexes 14:511 Asymmetric Michael addition 4:501, 502 in estrone synthesis 4:501,502
881
Asymmetric osmylation 19:269 Asymmetric oxidation 14:517,518 of prochiral sulfides 14:517,518 of sulfide 4:489 sulfoxides from 14:517,518 with chiral sulfamyloxaziridines 4:489 with chiral titanium complexes 4:489 Asymmetric quaternization 10:426-428 by Claisen rearrangement 10:426-428 by consecutive alkylation 10:405,406 of aldohexofuranose derivatives 10:428-432 of c~-carbon of 7-1actones 10:405 Asymmetric reduction 10:410 by Baker's yeast 10:410 of acetoacetic acid ethyl ether 10:410 of acetylenic ketone 11:424 of acyclic 13-hydroxy ketones 14:183,184 of 13-keto esters 14:533,534 with Baker's yeast 1:689 with Ipc2BH 8:476 Asymmetric synthesis 24:744-754,761, 766,767,772,773,775,777,780,781 by diastereofacial selection 13:62-70 by enantiofacial selection 13:70-73 by enantiotopic discrimination 13:60-62 of (+)-azaisopicrostegnane 24:775,777 of conidendrin 24:772,773 of 2,3- dibenzylbutyrolactones 24:744-754 of (+)-gomisin A 24:775-777 of (+)-isolarresinal 24:767 of (+)-isoschizandrin 24:775,777 of (-)-isoschizandrin 24:780,781 of (+)-paulownin 24:761,766 of (-)-podophyllotoxin 24:767, 775
of (+)-schizandrin 24:775-777 of (-)-schizandrin 24:780,781 of paraherquamide A 28:331,367 of carbaoxirose/carbaoxetoses 29:490 of (-)-ajmalicine 14:563,564 of (-)-sibirine 14:539-544 of (+)-(S,S)-solenopsin A 6:431, 432 of (+)-castanospermine 12:346 of (+)-elaeokanine A 12:351,352 of (+)-elaeokanine C 12:351,352 of (R)-muscone 14:490 of (MS)- 1,6-dioxaspiro [4.5] decane 14:523,524 of (R/S)-1,7-dioxaspiro [5.5]undecane 14:521-526 of [m, n, 1] propellanes 14:490 of 2-deoxy-D-arabino-hexose 14:176,177 of 3-deoxy-D-ribo-hexose 14:176 of 4-acetoxy-3-[ 1'-(tertbutyldimethyl-silyloxy) ethyl]azetidinone 4:448 of 4-deoxy-D-lyxo-hexopyranose 14:176 of 5, l-linked naphthylisoquinoline alkaloids 20:420-438 of 5,8-1inked naphthylisoquinoline alkaloids 20:442-451 of 7, l-linked naphthylisoquinoline alkaloids 20:438-441 of anthracycline antibiotic 14:492,493 of azetidinone 4:448 of buphanisine 4:14,15 of chiral alkaloids 10:671-689 of chiral building blocks 14:551-581 of chiral isoquinolines 10:671 of chiral piperidines 10:671 of crinine 4:14,15 of desoxydaunomycinone 14:23 of indolizidine alkaloids 6:442, 443 of monomorine I 6:449,450 ofpyrrolidine alkaloids 6:442, 443
882
of pyrrolizidine alkaloids 6:442, 443 of R,S-4-hydroxycyclopentenones 6:315 of solamin 18:202-206 of talaromycin A and B 14:531-539 propane- 1,3-diols by 13:53-105 via chiral organoboranes 8:465-478 with chiral sulfur reagents 10:671-689 Asymmetric transformation 13:77 crystallization-induced 13:77 of malonic acid derivative 13:88 Asymmetric 11:367 alkylation 11:367 catalytic epoxidation 11:431, 432 catalytic osmylation 11:431,432 cycloaddition 11:358 dihydroxylation of 11:423,424 trans-stilbene 11:423,424 Asymmetrization 11:241,242 of (y-symmetric ketones 11:241,242 Atromentin 29:296 biosynthesis of 29:296 Atta-ur-Rahman synthesis 14:850 of (+_)-16-hydroxydihydrocleavamine 14:850 of (+_)-16-methoxycarbonyldihydrocleavamine 14:850 of (+)-coronaridine 14:850 of (+)-dihydrocatharanthine 14:850 of (+_)isovincadifformine 14:850 of (+)-~-dihydrocleavamines 14:850 of (+)-[3-dihydrocleavamines 14:850 of anhydrovinblastine 14:857 of vinblastine 14:850-859 of vincristine 14:850-859 Atta-ur-Rahman's first synthesis 14:850-859 biosynthesis of 4:31 Buchi's synthesis of 14:868,869
first synthesis of 4:32 from catharanthine 14:854-858 from Catharanthus roseus 8:283;14:805 Gorman's synthesis of 14:862-864 Kuehne's synthesis of 14:831-849 Kutney's synthesis of 14:805-821 Magnus's synthesis of 14:821-830 N-demethyl deacetylvindoline from 14:862,863 Potier's synthesis of 14:869-873 Schill's synthesis of 14:861,862 synthetic approaches to 14:805-884 synthesis of 5:187-189 Takano's synthesis of 14:865-867 velbanamine from 14:862,863 Automated synthesis 13:257-294 of oligonucleotides 13:257-294 of oligodeoxyribonucleotides 4:280 reaction cycle 4:281 Automatic DNA synthesizer 4:304 Autooxidation 14:335,336 of l-methylazulene 14:335,336 of benzylic positions 16:571 of guaiazulene 14:316-319 of phenylhydrazine 9:581 Axial 2-1ithiotetrahydropyrans 10:380 by reduction with lithium di-tertbutylbiphenylide 10:380 from 2-(phenylthio)tetrahydropyrans 10:380 Axial C-glycopyranosides 10:365,366, 382 Axillarin 7:26 Aza-[2,3]-Wittig rearrangement 19:22, 45,50 2-Azaallyl anions 1:344-347 by deprotonation of imines 1:344-347 by C-Si of C-Sn bond cleavages 1:344-351,353 from imines 1:344-347
883
from N-lithioimidazolidines 1:344,349-351 from N-metalloaziridines 1:344,348,349 generation of 1:348,350 geometry of 1:348,350 Azaallylic anions 4:547 with aryl halides 4:547 Aza-annulation 18:315-386 of enamine related substrate 18:315-386 Aza-annulation reaction 18:373-386 asymmetric induction in 18:373-386 Azabicyclo ketone system 14:571-574 asymmetric cleavage of 14:571-574 cis-o~,c~'-disubstituted piperdine by 14:571-574 pyrrolidines by 14:571-574 Aza-Claisen rearrangement 16:467 Aza-Cope reaction 16:481 Aza-Cope rearrangement 1:68,69 Mannich directed 1:68,69 Aza-Cope-Mannich strategy 16:435 Aza-Diels-Alder approaches 16:456 Azadiene Diels-Alder 3:311 1-Azadiene Diels-Alder cycloadditions 16:457 2-Azadienes 4:7,10-14,17 metalloenamines from 4:7, 10-14,17 2-Azahexatriene 3:395 thermal cyclization of 3:395 Azatidine acetates 23:195 isomerization of 23:195 Aza-Wittig reaction 1:168,169 Azetidione derivatives 13:500 Mori's synthesis of 13:500 Azidation reaction 19:311 asymmetric 19:311 Azides 3:49 dipolar cycloaddition 3:49 thermolytic cyclization of 6:429 Azido-ene reaction 16:473 Azidonitration 1:420,421;10:465 Azido-olefin cyclization 13:447,448 Aziridine 10:138,139 from (S)-phenylglycinol
10:138,139 azomethine ylides from 1:328-331 fused 1:189,197 nucleophilic opening 1:201,202 photochemical opening 1:328 synthesis of 1:189,197 thermal opening in 1:328 2,2'-Azobisisobutyronitrile AIBN 24:16-18 Azomethine ylide cycoadditions 1:329,330 by aziridine thermolysis 1:329, 330 intramolecular 1:329,330 Azomethine ylides 1:331-332 by 1,2-H shifts 1:331-332 formation of 1:324-344 generation of 1:324,339 preparation by aziridine opening 1:328-331 preparation by desilylation 1:324-328 preparation from c~-amino acids 1:331-338 Azulenes 14:332 autooxidation of 14:332 electrochemical oxidation of 14:325 oxidation of 14:332-334 Baadische Anilin 28:71 vitamin A synthesis by 28:71 Backbone rearrangements 7:159, 161-166
Bacogenin A~ 23:503,511 transformation of 23:503,511 Baeyer-Meerwein rearrangement 24:30-32 Baeyer-Villiger oxidation 24:30-32,42, 43,191,192 Baeyer-Villiger reaction 27:94 9-hydroperoxy- 10,12,15octadecatrienoic acid by 27:74 Baeyer-Villiger rearrangement 4:139, 153,647,667 ;8:154,597,598;27:74 Baeyer-Villiger ring expansion 13:601
884
Bakankosine 26:101,102 chemical transformation of 26:101,102 Baker's yeast 4:158,263,324,325,340, 341,410,542,543,552,553;6:13; 10:410;13:58,59,307,309;20:573, 593,818,820 Baker's yeast reduction 13:662,176 Baldwin's rule 14:792,793 Ban condensation 1:135 Banerjee 29:174 pisiferic acid synthesis by 29:174 Banerjee and Az6car 29:208 triptolide synthesis by 29:208 Banerjee et al. 29:194,215 Carnosic acid synthesis by 29:194 miltirone synthesis by 29:215 Banwell 29:377,378 allocolchicinoids total synthesis by 29:377,378 Baogongteng A 21:751,752 synthesis of 21:751,752 Bartlett demethylation 8:119 Barton oxidation 13:72 9-BBN (9-borabicyclo-[3.3.1 ] nonane) 13:72 Barton radical decarboxylation 18:75, 340 Barton reaction 14:160 Barton reduction 12:303 Barton's modification 19:135 Barton-Crich's decarboxylative oxygenation 24:43,44 Barton's procedure 6:282-288,607 Barton's protocol 6:21 in free radical deoxygenation 6:21 Barton's reaction 6:228,230,231 Barton-type deoxygenation 20:71 Base promoted cyclisations 4:541 of aryl halides 4:541 Base-catalyzed equilibration 14:460 Base-induced rearrangement 12:91 mechanism of 14:372-374 of hydroazulene mesylates 14:22-25 of hydronaphthalene- 1,4-diol monosulfonate esters 14:356
of hydronaphthalene tosylates 14:368-370 Baudoin-Gu~ritte 29:407 rhazinilam synthesis by 29:407 Bayer-Villager oxidation 25:425 24-epi-catasterone by 25:425 9-BBN 4:116,117 reduction with 4:116,117 trans-BC-ring fusion 12:205 stereochemistry of 12:205 Beaucage sulfurizating agent 13:269 Beckman fragmentation 19:486 of anti-oxime 19:486 of erythromycin-9-oxime 13:160,161 of oxacyclopentanone ring 16:221 of oxime 16:240,330;19:14,498 Bellus rearrangement 8:205 Benz-annulation reaction 1:505,506 Benzene ring 27:355 steric effect of 27:355 Benzilic-type rearrangement 3:226 1,4-Benzoquinones 16:547-570 enantiospecific reactions of 16:547-570 stereospecific reactions of 16:547-570 Benzosampangine 23:3,5,42 biotransformation of 23:3,5,42 Benzoxazinoid acetal glucosides 27:191-194 chemical synthesis of 27:196,207-210 enzymatic degradation of 27:191-196 Benzoxazinones 27:185-225 synthetic access to 27:185-225 Benzoxazione aglucones 27:190-191, 195,196-207 chemical synthesis of 27:196-205 synthesis of analogues 27:205-207 2,4-Benzoxazocine derivative 6:469 by ring expansion 6:469 Benzoxazocine derivatives 6:468-471 by ring construction 6:468-471 by ring destruction 6:468-471
885
by ring interconversion 6:468-471 from o~-narcotine N-oxide 6:468 synthesis of 6:468-471 1,5-Benzoxazocine N-oxide 6:472 1,6,5-benzodioxazonine from 6:472 thermolysis of 6:472 Benzoxazolidone derivative 12:164,166 boron enolate of 12:164,166 C4-alkylation by 12:164,166 stereoslective 12:164,166 2,5-Benzoxazonine 6:473 carbocation intermediate in 6:473 derivatives of 6:476,47 photosolvolysis of 6:475,476 synthesis of 6:473 N-Benzoylcarbamate 14:569 cyclization of 14:569 from 2,3-epoxy alcohol 14:569 2-oxazolidinone from 14:569 N-Benzoylpyrrolinone 8:212,213 synthesis of 8:212,213 1-Benzyl-2,6-dicyanopiperidine 6:433 alkylation of 6:433 decyanation of 6:433 2,6-dialkylpiperidines from 6:433 1-Benzyl-3-methylnaphthalene 30:217 formation of 30:217 from phenylacetone 30:217 Benzyl-4,6-O-benzylidene-3-deoxy-13-Dribo-hexopyranoside 14:11,12 synthesis of 14:11,12 Benzylation 6:268-270,287,288 O-Benzylation 12:327 N-Benzylation 7:41-43 of 1,4-dideoxy- 1,4-imino-Lallitol 7:41-43 Benzylic hydroperoxide rearrangement 3:316-319 3,5-O-Benzylidenation 12:52,53 of (9S)-9-dihydroerythronolide A 12:52,53 Benzylidene glycal 10:344 Benzylisoquinolines 3:422 synthesis of 3:422
Benzyllithium 8:6 alkylation of 8:6 Benzyloxycarbonylation 12:478 Benzyne cyclization 4:541-551 Benzyne reaction 16:514 BF3 rearrangement 5:782,783 BF3-mediated method 11:117 Bianco 29:487 valienamines synthesis by 29:487 Bicyclic C-glycoside 30:470 cleavage of 30:470 Bicyclic I]-lactam 12:172,173 by Diels-Alder reaction 12:172,173 from cyclic imines carboxylic acid 12:117 from 2H-4H, 1,3-dioxin derivatives 12:160,161 synthesis of 12:172,173 Bicyclo [2.2.1 ] heptanes 8:415 synthesis of 8:415 Bicyclo [2.2.2] octane 6:70,71 (+)-sanadaol from 6:70,71 by double Michael addition 8:422 from Li-cyclohexadienolates 8:422 from o~,[3-unsaturated esters 8:422 synthesis of 8:4! 2-422 Bicyclo [3.2.1] octadione 8:161,162 synthesis of 8:161,162 Bicyclo [3.2.2] piperazinedione 12:71 synthesis of 12:71 Bicyclo [3.3.1] nonanes 3:95 conformation of 3:95 fragmentation of 3:74 Bicyclo [4.3.1] dec-2-en-7-one 6:69 by Grob fragmentation 6:69 by intramolecular [2 + 2] photocycloaddition 6:69 synthesis of 6:69 Bicyclo [4.3.1] decanone 6:70 nakafuran-9 from 6:70 synthesis by four carbon polar annulation 6:17,21
886
Bicyclo [5.2.2] piperazinedione 12:84, 85 synthesis of 12:84,85 Biellmann coupling 10:6-10 Bimolecular [6~+4~] tropone diene 12:241 cycloaddition of 12:241 Bimolecular conjugate addition 24:768 Bimolecular cyclization 24:769 BINAP 13:72 BINAP-Ru-catalyst 4:439 in asymmetric hydrogenation 4:439 Bioactive marine natural products 21:293 biosynthesis of 21:293 Bioactive terpenes 24:175-213 from Wieland Miescher ketone 24:175-213 Bioflavours 25:125128,129,294,300, 329,401,659,661,662 de novo synthesis of 25:128,129, 294,300,329,401,659,661,662 Biogenesis 23:204,211,253,255, 395-453;27:515 ofmanzamenone K 23:204,211 of ellagitannin oligomers 23:395-453 of ecteinascidins 23:253,255 of swainsonine 27:515 Biological Diels-Alder reaction 17:451 Biological screening 29:366 allocolchicinoid synthesis for 29:364 Biomethylation 9:47 Biomimetic cationic polyene cyclization 12:456 Biomimetic cyclization 14:681-684 of allylic alcohol 14:681-684 Biomimetic olefin cyclization 1:671-673 Biomimetic polyene cyclisations 7:131 Biomimetic synthesis 24:743 Biosynthesis 21:293;23:51,79; 27:321;29:295 abscisic aldehyde in 27:321 by Read and Vining 29:295 in Clitocybe subilludens 29:296
in Peniophora sanguinea 29:298 in Phleba strigosozonata 29:296 of ansamycins 23:51,79 of ascocorynin 29:296 of atromentin 29:296 of bioactive marine natural products 21:293 of deoxylapachol 29:736 of ecdysteroids 29:5 of gingerol 23:848 of isocyanide group 21:349 of isoprenyl- 1,4-naphthoquinones 29:735 of lapachol 29:734 of lawsone 29:736 of lignans 24:742-744 of macrolide antibiotics 29:322 of manool 25:253,254,259 of melanin 26:1019 of menaquinone-1 29:736 of nitrogen compounds 29:328 of ortho-terphenylquinone phlebiarubrone 29:296 of polyhydroxy-p-terphenyl 29:295-297 of scopadulan-type diterpenoids 21:721-723 of streptovaricin D 23:64 of terphenyllin 29:296 of tetracyclines 29:312 of thelephoric acid 29:296 of triterpenoids 22:97 of volucrisporin 29:295 of xylerithrin 29:298 zeaxanthin in 27:321 Biosynthetic pathways 24:846,847 for production of natural products 24:846,847 Biosynthetic studies 23:266,260 of [3-carbolines 23:260,266 Biotransformation 23:3,5,42;24:74-76, 309-318 of benzosampangine 23:3,5,42 of cis-6fl-sesquiterpene 24:74,75 of 6fl-eudesmanolioes 24:76 Biotransformation rates 27:377 Birch reduction 11:286 of o-toluidine 11:286
887 of 6-methoxy-l-tetralone 12:235 of 4-methoxytoluene 12:22-24 ofp-cresyl methyl ether 6:83,84 Bis (trimethylsilyl) ethylene glycol 1,3-dioxolane formation 1:584 reaction with aldehydes 1:584 reaction with ketones 1:584 Bis (trimethylsilyl)- 1,2-ethanedithiol 1,3-dithiolanes 1:584 reaction with aldehydes 1:584 reaction with ketones 1:584 [B is(tri fl uoroaceto xy )iodo ]ben zene 30:439 as reagent 30:439 Bischler-Napieralski reaction 3:460, 93,633,790;8:291 Bischler-Napieralski condensation 14:763 isokomarovine from 14:763 komarovidine from 14:763 of tryptamine 14:763 with quinoline-5-carboxylic acid 14:763 Bischler-Napieralski cyclization 4:20, 23,444 Bis-Fischer indolization 12:376,377 Bisketene 4:349 Bis-quinolizidnie macrocycles 24:606 synthesis of 24:606-609 total synthesis of 24:610,611 Blue oxonium ions 30:531,532 formation of 30:531 via cyclic hemiketals 30:532 Boat-boat inversion potential 27:343 of 1,4-cyclohexadiene 27:343 BOC anhydride method 12:121 BOC functionality 4:91,92 deblocking with TMSOT 4:91,92 (R)-N-BOC-2-amino alcohols 12:435, 436 with thionyl chloride 12:435,436 N-BOC-L-threonine methyl ester 12:430 from methyl trans (4S,5R)-5methyl 3-tert butoxycarbonyl-2o x o-ox azol idi ne- 4- c arbo xyl ares 12:430 N-BOC-tyrosine 16:609 photooxygenation of 16:609
Boekman-Silver synthesis 6:18 of (-)-[3-gorgonene 6:18 Bombesin analog 27:797 lrom emphibianskin 27:797 Borane-methyl sulfide complex 11:360 Boration 9:366-368 Bormination 4:629,633,634,656,657 of camphor 4:629,633,634, 656,657 of camphor derivatives 4:629632,633,634,636,656-658 Born-Oppenheimer approximation 2:155 Boron aldolate 30:23 in situ reduction of 30:23 Boron enolate 13:500 of 3 (R)-3-hydroxybutanethioate 13:500 Bose reaction 4:440,441 by 3-hydroxybutyric acid 4:440,441 by ketene-imine cycloaddition 4:440 in azetidinone formation 4:440, 441 Bovine serum albumin 27:330 phytolysis of 27:330 Boy~/Brossi 29:378 allocolchicinoids total synthesis by 29:378 Boyer and Hanna 29:497 carbaoxirose/carbaoxetoses synthesis by 29:497 Boyer and Lallemand 29:499 homochiral (+)-calystegines B2 synthesis by 29:499 homochiral (-)-calystegines B2 synthesis by 29:499 Bradsher cycloaddition 24:630,631 Branched amino sugars 10:421 synthesis of 10:421 Branched chain nucleosides 4:254-257 synthesis of 4:254-257 Branched decarbonucleotide 14:299,302 synthesis of 14:299,302 Branched hexaribonucleotide 14:291, 292 synthesis of 14:291,292
888
C-Branched nucleoside analogues 19:511-547 stereoselective synthesis of 19:511-547 Branched oligoribonucleotides 14:283-303 synthesis of 14:283-303 Branched RNAs 14:293 synthesis of [A(2'-pX)pX] 14:293 synthesis of [A(2'-pY)pX] 14:293 synthesis of [A(2'-pU)pU 14:293,294 synthesis of [CpUpA(2'-pGpU) pUpC] 14:299,301 synthesis of 14:284-303 via 3'-bis(2-cyanoethoxy) phosphoryl group 14:291,292 via 2',3'-bisphosphorylated ribonucleoside unit 14:284-290 via phosphoramidite approach 14:293,294 Branched tetrasaccharide 10:476,477 synthesis of 10:476,477 Branched triribonucleotide 14:294,295 synthesis of [A(2'-pA)pA] 14:294,295 synthesis of [A(2'-pG)pC] 14:289,290,297-299 synthesis of [A(2'-pG)pU] 14:290,298-300 synthesis of [A(pG)pC] 14:289,290 synthesis of [araA(2'-pU)pU] 14:294 synthesis of [GpA(2'-pG)pC] 14:295-297 synthesis of [pA(2'-pA)pA] 14:294,295 synthesis of [pppA(2'-pA)pA] 14:294,295 synthesis of [U(2'-pA)pU] 14:296,297 Branched trisaccharide 10:476,477 synthesis of 10:476,477 Brchtold et al. 29:200,203 triptolide synthesis by 29:200, 203
Bredereck's reagent 8:262,316 Bredt's rule 12:72 Bromination 14:269 3-bromo-levoglucosenone 14:269 chemoselective 19:314 Bromination-dehydrobromination sequence 12:237 Brominative cyclization 6:24 in brominated terpenoids 6:24 in glanduliferol synthesis 6:63,64 of (8R/S,9R/S)- 8-brome-9hydroxy-(E)-bisabolene 6:62,63 Brominative rearrangement 4:474 4-Bromo-azetidinone 4:474 Bromine addition 16:336 Bromlactonisation 8:301 of bromolactone 8:301 of (4S)-3-methylmuconolactone 8:300,301 Bromoboronylether 30:214,215 boron tribromide from 30:214 conversion of 30:215 Bromocarbenoid procedure 1:263 Bromocarbenoid ring expansion 1:263 Bromodecanal 26:83 wittig reaction of 26:83-91 Bromohydrin fcmation 1:523 Bromolactoniz,.lon 3:265,336-339,177 c~-(Bromomethyl)acrylate 30:470 condensation with 30:470 Brook-Rubottom-Hassner oxidation 12:25,26 ofenol silane 12:25,26 Brown and Robin 29:392 steganes synthesis by 29:392 Brown's crotylboration 18:280 Btichi and Powell 29:472 carbaaldopyranoses synthesis by 29:472 Burgess reagent 1:16,50,53,232,257, 296,601, Burguess reagent 24:178,179 Butenylation 12:458 (E)-2-Butenyldiisopinocampheylborane 13:135 3-Butenylmagnesium bromide 12:29,30 N-tert-Butoxycarbonylation 12:478,479
889
t-Butyl acetate 11:127,129 Claisen condensation of 11:127, 129 with naphthalene glutarate 11:127,129 t-Butyl hydroperoxide 12:323 tert-Butyl hypochlorite 1:45! addition to olefins 1:451 cyclization with 1:11,12 tert-Butyl tin hydrite 1:443,444,451 reduction of chlorides 1:443, 444,451 reduction of dithiocarbonate 1:452,453 tert-Butyldimethyl silyl ether 6:264, 268; 11:339;12:282 tert-Butyldimethylsilyl (TBDMS) group 4:299,304 tert-Butyldimethylsilyl ketene acetal 1:465 tert-Butyldimethylsilylation 6:119,120 t-Butyldiphenylsilyl ethers (TBDPS) 24:9-11 tert-Butyldiphenylsilyl trifluoromethanesulfonate 1:707,708 N-I-Butyldiphenylsilyl-S-benzyl-Smethyl sulfoximine 10:686-688 tert-Butylformamidines 6:430,431 2-(t-Butylimino)-2-[(diethylamino)]-1,3dimethylperhydro- 1,3,2-diazaphosphorine 12:342 Butyrolactones 3:252-225 y-Butyrolactone 16:687-726 C2-P bond analogs 6:357,358 of D-erythritol 6:357,358 of D-fructofuranose 6:357,358 of D-glucopyranoside 6:357,358 of D-ribohexitol 6:357,358 C3-P bond analogs 6:359,360 of D-allofuranose 6:359 of D-altropyranoside 6:359,360 of D-glucofuranose 6:359,360 of D,L-glyceraldehyde 6:359 of D-xylofuranose 6:359 C4-alkylations 12:159-172 of 13-1actams 12:159-172 with ester enolates 12:163,164
with imide enolates 12:164-168 with other nucleophiles 12:170-172 with thiolester enolates 12:168-170 C4-P bond analogs 6:360,363,364 of D-erythropentose 6:360,363, 364 of D,L-glycero-pentopyranose 6:360,361 of D-talopyranose 6:360 of L-talopranoside 6:360 Cs-P bond analogs 6:365,366 of D-erythropentofuranose 6:365,366 of D-ribofurnose 6:365,366,368 of D-xylofuranose 6:365-367,375 of D-xylo-hexofuranose 6:365, 366,372 C6 oxidation 25:415,424 of 6-deoxocastasterone 25:415, 424 C6-P bond analogs 6:376 of D-arabino-hexofuranose 6:376 of D-erythro-hexofuranose 6:376 of D-galactopyranose 6:376 of D-glucofuranose 6:376 of D-glucopyranose 6:376 of D-ribo-hexofuranoside 6:376 of D-ribo-hexofuranose 6:376 Cs-polyketide 12:290 Camphorquinone rearrangement 16:150 Cannizzaro reduction 19:536 Capnellanes 6:42 from (-)-A9~12~-capnellene 6:42 synthesis of 4:588 Capnellene 3:11,13,19,20,22 synthesis of 3:11,13,19,20,22 (-)-A9~12~-Capnellene 6:42 capnellanes from 6:42 (+)-A9~12)-Capnellene 6:45 by c~-alkaynone cyclization 6:45 by [2+2] cycloaddition reaction 6:43,44 by [4+2] cycloaddition reaction 6:43,44
890
by cyclopropane sliding reaction 6:48 by Diels-Alder reaction 6:46 by intramolecular alkylation 6:42,43 by intramolecular diyl trapping reaction 6:46 by intramolecular reductive coupling 6:48 by intramolecular type I Mg erie reaction 6:45,46 by methylenation 6:46,47 by 1,2-methyl shift 6:48 by Nazarov cyclization 6:43 by photochemical annulation 6:48 by three-carbon annulation 6:42 Dreiding synthesis of 6:45 from [3-diketone 6:48 from humulene 6:48 Grubb synthesis of 6:46,47 Liu-Kulkarni synthesis of 6:43,44 Oppolzer-Batting synthesis of 6:45,46 Stille synthesis of 6:47 synthesis of 6:42,43 with Tebbe reagent 6:46,47 A9(~Z)-Capnellene 3:7;13:34,35 synthesis of 13:34,35 from Capnella imbricata 13:34, 35 A(Jz)-Capnellene 213,813,10or 3:7 A9(lZ)-Capnellene-3[3,8[3,10or 3:7
A9(12)-Capnellene-313,813,10[3-14-tetrol 3:7 Ag(12)-Capnellene-5or162 3:7 Capnellene-2[3,S[3,10~z-triol 3:64 Capnellene-3[3,SI3,10or tetriol 3:64 Capnellene-5(z,813,10o~-triol 3:64 A9(~Z)-Capnellene-8[3,10or 3:7 AS/(9)-Capnellene 3:20 synthesis of 3:20 Capnellenols 6:49,50 by aldol cyclization 6:49,50 by three-carbon annulations 6:49,50 synthesis of 6:48-50
Capping reaction 4:279,280 in oligonucleotide synthesis 4:279,280 Carbaaldofuranoses 29:452 synthetic strategies for 29:452 target-oriented (linear) synthesis of 29:452 Carbaaldopyranoses synthesis 29:467 building-block for 29:469 by Angelaud and Landais 29:467 by Btichi and Powell 29:472 by Emmons-Horner-Wadsworth 29:471 by furan-based Diels-Alder approach 29:470 by Metha and Mohal 29:470 by microbial transformations 29:469 by Sudha and Nagarajan 29:472 by Toyokuni 29:471 by Zanardi and co-workers 29:473 chiral sources for 29:467 conditions for 29:468 diastereoselective routes to 29:471 exploitation of natural carbohydrates for 29:471 of glycosidase inhibitors 29:467 Carbacephems 12:121 synthesis of 12:121 Carba-disaccharides 13:219-221 synthesis of 13:219-221 Carbafuranose synthesis 29:452 by agrofoglio 29:461 by Ddsir6 and Prandi 29:455 by Lowary and Callam 29:457 by Lundt and Horneman 29:456 by Metha and Mohal 29:462 by Monti 29:458 by Rassu 29:453 conditions for 29:453 from cis-fused bicyclic furanone 29:452 of 2 C-methyl-4ec-carba-[3-Darabinoaldofuranose 29:459 of 2 C-methyl-4oc-carba-[3-Dlyxoaldofuranose 29:459
891
of 4~-carba-~-D-xylofuranose 29:452 starting from norborn-5-en-2-one 29:452 Carbafuranoses 29:451 diversity-oriented synthesis of 29:451 5a-Carba-glycosylamines 13:195-204 synthesis of 13:195-204 5a-Carba-hexopyranoses 13:190-207 synthesis of 13:190-207 Carbaketofuranose synthesis 29:460 by A1-Abed and Seepersaud 29:460 by Wilcox and Gaudino 29:460, 461 conditions for 29:460 5-Carba-levoglucosenone 14:279 1,4-exo-aducts of 14:279 3-deoxy derivative of 14:279 synthesis of 14:279 Carbanion 16:30 Carbanion reagents 11:439-443 Carbanion rearrangement 16:620 Carbanions 1:351-353 Carbaoxirose/carbaoxetoses 29:490 asymmetric synthesis of 29:490 enantioselective synthesis of 29:492 synthesis by Boyer and Hanna 29:497 synthesis by Ichikawa 29:492 synthesis by Skaanderup and Madsen 29:496 Carbapenams 8:262,263 synthesis of 8:262,263 (+)-6~-Carbaprostaglandin I2 1:698,699 synthesis of 1:698,699 Carbaseptanoses 29:493 total synthesis of 29:493 Carbasugars (alias pseudosugars) 29:449,507 synthesis of 29:449,507 Carba-sugars (pseudo-sugars) 13:187-255 synthesis of 13:187-255
4c~-Carba-~-D-xylofuranose 29:452 carbafuranose synthesis of 29:452 Carbene complexes 16:406 Carbene insertion reaction 4:436,438 Carbene-diene cyclization 3:29 Carbene-olefin cyclization 3:325 Carbenoid displacement 1:259 Carbenoid insertion 13:501-503 Carbinolamides 4:57 Carbinolamine 4:57,269,270 Carboalumination 1:454,455,459 with Me3A1, ZrCp2C12 1:454, 455,459 Carbocation intermediate 6:474 in 2,5-benzoxazonines syntheses 6:474 Carbocupration reaction 14:507,508 asymmetric induction in 14:507, 5O8 diastereoselective 14:507,508 of C2-homochiral cyclopropenes 14:507,508 Carbocycles 8:272 from palladium (+2)complexes 8:272 Carbocyclic oxetanocins 10:608-619 synthesis of 10:608-619 Carbocyclic spiro compounds 14:544-546 asymmetric synthesis of 14:544-546 2-Carboethoxy-2-deoxy-2-ulosoic acid esters 30:467 decarboxylation of 30:467 Carbohydrate derivative 14:659-664 synthesis of 14:659-664 via Norrish type II reaction 14:659-664 Carbohydrate lactones 10:385 C-glycosides from 10:385 13-Carbolines 23:260,266 biosynthetic studies of 23:260, 266 (+)-Carbomenthone 6:547,548 Robinson annulation of 6:547, 548 Carbomethoxylation 4:36,38 of ketone 4:36,38
892
Carbon versus oxygen alkylation 4:367 regioselectivity of 4:367 Carbon-bridged system 12:87 Carbonolides 11:163-172 stereoselective synthesis of 11:163-172 synthesis of 11:158-172 Carbon-tin bond 1:352,353 conversion to carbon-silicon bond 1:352,353 Carbonyl coupling reaction 8:16-18 titanium induced 8:16-18 Carbonyl reduction 1:622 diastereoselective 1:622 of I3-keto acetals 1:622 Carbonyl tosylhydrazone 30:32 reductive deoxygenation of 30:32 1,2-Carbonyl transposition 3:474,485 Carbonylation 19:189,195 palladium catalyzed 19:189,195 Carbopalladation 16:374 Carboxylation 11:195 (2S)-methylmalonyl CoA by 11:195 of propionyl CoA 11:195 Carboxylic acid 30:23 debenzylation of 30:23 oxidation of 30:23 Carboxylic acid anhydride variation 4:375 of Claisen condensation 4:375 Carboxylic acid silyl esters 4:564 with silylated phosphonium ylides 4:564 Carboxylic esters 6:334 into aldehydes 6:334 synthesis of 6:326327 Carbylamine reaction 12:113 isocyanides by 12:113 Carcinoembryonic antigen (CEA) 29:552 periodate oxidation of 29:552 Cardol 30:146 by decarboxylation 30:146 Carnosic acid synthesis 29:191 by Banerjee et al. 29:194 by Meyer et al. 29:191
by Tiam et al. 29:198 starting material for 29:191 Carnosolic acid 29:575 7-O-Methylrosmanol (abietane diterpene) synthesis from 29:575 Carnosolic acid 29:575 rosmanol (abietane diterpene) synthesis from 29:575 I]-Carotene 30:516,520,524,537,539544,546,548 protonation of 30:546,548 Carrol conditions 6:122 Carrol rearrangement 10:58,60 Carrol-Claisen rearrangement 6:417 Carvone 27:378 of optical isomers 27:378 D-Carvone epoxide 10:43 Horner-Emmons reaction of 10:43 Lythgoe aldehyde from 10:46 C-Aryl glycoside 10:370 stereoselective synthesis of 10:370 C-Arylglycals 10:344 by palladium catalyzed coupling 10:344 synthesis of 10:344 Catalysts 4:302 Catalytic asymmetric aldol reaction 18:485 Catalytic detoriation 9:476 Catalytic epoxidation 11:431,432 Catalytic hydrogenation 6:425;19:77; 24:179,180;30:454 of a r a b i n o isomer 30:454 of racemic ketoacid 24:181,182 with raney nickel 6:425 with rhodium 6:424 Catalytic hydrogenolysis 12:163,293; 22:277 Catalytic osmylation 11:431,432 Catalytic receptors 18:694 Catalytic reduction 19:76,91 Catalyzed rearrangement 16:512 (+)-Catechin 27:774 oxidation of 27:774 Catechol borane reduction 13:562
893 Cationic cyclization 14:793-795 (+)-chelamine by 14:793-795 (+)-chelidonine by 14:793-795 sanguinarine by 14:793-795 Cationic cyclopentannelation reactions 14:583-630 Cationic polyene polymerization 1:565 Cationic rt-cyclization 12:287 of N-acyliminium ion 12:287 C-C bond formation 6:307-349 Ce (OAc)3-BF3OEh 10:572 Ceric ammonium nitrate 4:322,323, 331,332 Ceric chloride 1:552 Cerium (III) chloride 14:753 Cerium ammonium nitrate (CAN) 14:780 Cerium carbanion 1:552 Cesium fluoride 1:563,564 (~-C-Glycosides 10:381 by condensation of methylallyl tri-n-butylstannane 10:381 by condensation with furan 10:377 by reaction of acyl ester 10:371 from pyridyl thioglycoside 10:382 from c~-tri-n-butyltin glycoside 10:384 stereoselectivity of 10:371 with allyltrimethylsilane 10:371 [3-D-C-Glycosides 10:383,384 from 3,4,6-tri-O-t-butyldimethylsilyl-2-deoxy D-glucopy ranosyl phenylsulfone 10:383, 384 C-Glycosyl compounds 10:373,374 by catalytic siloxymethylation of O-acylglycosides 10:373,374 by reaction with HSi R3/CO/ Co2(CO)8 10:373,374 C-Glycosylarenes 10:380 by reaction of benzoylated Oalkyl glycosides 10:380 C-Glycosylation 10:387 of aromatic ring 10:387 of heterocyclic ring 10:387
C-Glycosylcyanides 10:355 from acylated bromosugars 10:355 synthesis of 10:355 C-Glycosyl-oxirans 10:361 from acetobromoglucose 10:361 CH3SOCH2 27:512 from dimethylsulphoxide 27:512 Chactomellic acids 24:418-428 synthesis of 24:421-426 Chalcone synthesis 21:742 Khan's method for 21:742 Chan-Brownbridge procedure in (-)-pseudopterosin-A synthesis 6:74,75 Chelate model 11:268,269 Chelating transition state models 12:167 s-Chelation 11:234 13-Chelation 11:234 Chelation 12:149,150 Chelation controlled aldol condensation 10:286 Chelation controlled Grignard reaction 1:266 Chelation directed addition 3:271 Chelation-controlled addition 14:50 Chelation-controlled alkylation reaction 30:12 Chelation-controlled reduction 30:11 Chelation-controlled Sakurai reaction 12:333 Chelilutine 27:156-166 chemical reactivity of 27:166 isolation of 27:164-166 Chemical degradation 23:30; 27:191 - 196 of benzoxazinoid acetal glucosides 27:191-194 of low density lipoprotein 27:846 of SAMM 2 23:30 Chemical reactivity 27:156-166 of chelilutine 27:156-166 Chemical synthesis 27:196,207-210 of benzoxazinoid acetal glucosides 27:191-194 of benzoxazione aglucones 27:190-191,195,196-207
894
Chemical transformation 26:10 l, 102 of bakankosine 26:10 l, 102 of secologanin 26:97,99 of sweroside 26:103,104 Chemoselective epoxidation 14:366 Chemoselective hydroxylation 6:79 of bicyclic triene 6:79 Chemoselective reduction 10:85;30:25 of unsaturated ester 30:25 with lithium tri - t e r t butoxyaluminohydride 10:85 Chida's synthesis 30:38-40 of (-)-pironetin 30:38-40 Chiral 1,3-dioxane 14:480 Chiral 1,4-dihydropyridine 14:744 isonitramine from 14:744 Chiral 1-acylpyridinium salt 12:351 Chiral 2-amino alcohol 12:415,416 synthesis of 12:415,416 Chiral 4-hydroxyoxazolidin-2-ones 12:450 Chiral acetals 14:506,507 asymmetric cyclization of 14:506,507 asymmetric synthesis from 14:496-516 bromination of 14:505,506 diastereoselective 14:505,506 for asymmetric bromolactonizations 4:338,339 from (-)-(2S,3S)- 1,4-dimethoxy2,3-butanediol 14:496 from (2R,4R)-pentanediol 14:473 from (2S,4S)-pentanediol 14:481 from 1,3-diphenylpropane- 1,3diol 14:480 from C2-symmetric diols 14:469-516 from dialkyl tartarate 14:505,506 from perillene 14:506,507 nucleophilic additions of 4:330-332 preparation of 4:324 with methallylsilane 14:481 with trimethylsilyl cyanide 14:473 Chiral acetylenic acetals 14:471 chiral alkoxy-allenes from
14:471 with Grignard reagent 14:480 Chiral acrylates 8:416 Chiral acyclic [3-keto acetals 14:501 from (-)-(2R,3R)-2,3-butanediol 14:501 LiA1Hm-reduction of 14:501 Chiral alcohols 14:470 Chiral alkoxy-allenes 14:480 from chiral acetylenic acetals 14:480 synthesis of 14:480 Chiral alkyl (l,3-butadien-2-yl) methanols 14:474 Chiral allylboronates 11:423,424 synthesis of 11:423,424 Chiral allylic alcohols 4:160-161 Chiral amide bases 10:31-33 [2,3] Wittig ring contraction with 10:31-33 Chiral amines 14:496 from chiral imine 14:496 Chiral aryl Grignard reagents 14:508,509 diastereoselective addition of 14:508,509 Chiral arylaldehyde acetal chromium tricarbonyl complexes 14:511 asymmetric metallation of 14:511 Chiral auxiliaries 4:327 acetals as 4:327 asymmetric induction with 4:327-345 binaphthyl diols as 4:335 by (R)-(+)-~-methyl benzylamine 4:324 by 1-(-)-methyl ester 4:323 chiral diamides as 4:335 glycosides as 4:327 in asymmetric Diels-Alder reaction 4:345 in Diels-Alder reactions 4:334-336 oxazolines as 4:327,332,333 preparation of 12:416-418 prolines as 4:327 stereo-differentiating reactions 4:327
895
Chiral
Chiral
Chiral Chiral Chiral Chiral Chiral
Chiral
Chiral
Chiral
Chiral
sugar as 4:334-336 thiazolidine derived 14:735 boron reagent 4:609 from B (OCH3)-(R,R)-(+) tartaric acid 4:609 in asymmetric Diels-Alder 4:609 building blocks 13:73-84 from malonic acid derivatives 13:73-84 monofluorinated 13:81 preparation of 4:349-359,73-84 asymmetric synthesis of 14:551-581 via intramolecular Michael reaction 14:551-567 carbapenems 12:121 catalysts 17:479 chromatography 18:411 cyclized hemiacetal 14:487 from chiral vinyl ether 14:487 cycloalkanone acetal 14:486 chiral vinyl ether alcohols from 14:486 from (-)-(2R,4R)-2,4-pentane diol 14:486 cyclopropanation 14:401-405 of chiral pyrethroid analogues 14:401-405 of thujone 14:401-405 dienophiles 8:140 c~-hydroxcarboxylic acid derivatives 8:140 cycloaddition of 14:503 isoquinolinium salt with 14:503 dienyl ether alcohol 14:487,488 (+)-africanol from 14:487,488 cyclopropanation of 14:487,488 dioxane acetals 14:476 asymmetric nucleophilic cleavage of 14:476 diastereoselective cross-aldol reaction 14:472 from (2S,4S)-2,4-pen tanediol 14:471 from (2R,4R)-pentanediol 14:477,478 with organometallic reagents 14:476
Chiral
Chiral
Chiral Chiral
Chiral Chiral
Chiral
Chiral Chiral Chiral Chiral Chiral Chiral Chiral
Chiral
with Reformatsky reagents 14:477,478 enamine 14:553 asymmetric 14:553 intramolecular Michael reaction of 14:553 enol ethers 14:489 asymmetric 14:489 C-N bond formation 14:489 enone acetal 14:510 epoxidizing agent 4:172,173 diastereofacial selectivity of 4:172,173 chiral lactones 4:493 from tx,[3-acetylenic alcohols 4:493 from keto acids 4:493 preparation of 4:493 ester 14:552 fragments 6:282 of amphotericine B 6:282 synthesis of 6:282 imine 12:161 [2+2] cycloaddition of 12:161 from ethyl (S)-lactate 12:161 addition of organometallic reagents 14:496 chiral amine from 14:496 imine acetal 14:497,498 with lithium enolate 14:497,498 inducer 1:73 induction 18:480 with Schoellkopf reagent 10:653,655 isoquinolines 10:671 synthesis of 10:671 Lewis acids 8:140 monoterpenoids 27:361 isomerism of 27:361 N-acylated 2-oxazolone 12:419 2-amino alcohol synthon from 12:419 electrophilic addition of 12:419 from camphor-derived carboxylic acid 12:419 with bromine and phenyl selenyl chloride 12:419 with DPPOx 12:419 N-glycosyl nitrones 1:370,371
896
Chiral nitroolefination 14:631-644 of enolates 14:631-644 Chiral ortho ester 14:508 from diethyl (L)-tartrate 14:508 Chiral ortho ester vinyl ethers 14:503 Chiral oxazolines 4:333 Chiral piperidines 10:671 synthesis of 10:671 Chiral precursors 6:298,299 aspartic acid as 6:298,299 (S)-3-hydroxybutyrate c~ 6:300,301 (R)-methyl-p-tolylsulfoxide 6:301,302 Chiral pyrethroid analogues 14:398-405 from thujone 14:398-405 synthesis of 14:398-405 via chiral cyclopropanation 14:401-405 Chiral reduction 1:482 Chiral reproduction 4:346 Chiral sesquiterpenes 14:406-425 synthesis of 14:406-425 via Robinson annulation reaction 14:406-425 Chiral shift reagent 4:326 Chiral steroid analogues 14:431-444 synthesis of 14:431-444 Chiral steroidal acetal 14:481,482 from (2R,4R)-(-)-pentanediol 14:481,482 from (2S,4S)-(+)-pentanediol 14:481,482 with organometallic reagent 14:481,482 Chiral sulfamyloxaziridines 4:489 asymmetric oxidation with 4:489 oxidation of sulfides with 4:489 Chiral sulfoxides 10:671-685 to 3,4-dihydro-6,7-dimethoxyisoquinoline 10:679-685 Chiral sulfoximines 10:671-679 intramolecular addition to 10:671-679 to 3,4-dihydro-6,7-dimethoxyisoquinoline 10:679-685 Chiral sulfur reagents 10:671-689 asymmetric synthesis with 10:671-689
Chiral sulphoxide 14:747 (-)-sibirine from 14:747 Chiral synthesis 12:477 of amino acid 12:477 of 1-(c~-hydroxyalkyl)- 1,2,3,4tetrahydroiso quinolines 12:450 of bioactive natural products 13:84-99 of bioregulators 6:537-566 of semiochemicals 6:537-566 Chiral synthon 1:482 with yeast 1:482 for 2-aminoalcohols 12:416-425 Chiral tartaric amides 4:338,339 trans-acetalization of 4:338,339 Chiral template effect 12:489,500 Chiral templates 14:267-281 Chiral tertiary alcohols 14:491,492 asymmetric synthesis of 14:491, 492 from chiral c~-keto acetals 14:491,492 Chiral titanium complexes 4:489 asymmetric oxidation with 4:489 oxidation of sulfides with 4:489 Chiral vinyl ether alcohols 14:486 from chiral cycloalkanone acetals 14:486 synthesis of 14:486 Chiral vinyl halide 12:35,36 coupling reaction of 12:35,36 with chiral s-methyl-substituted aldehyde 12:35,36 Chiral vinyl sulfoxides 10:671-679 intramolecular addition to 10:671-679 Chiral vinyllithium compounds 12:35-62 addition reaction of 12:35-62 Chiral -cyano alcohols 14:475 from achiral ~-methoxycycloalkanone oxime acetates 14:475 synthesis of 14:475 via Beckmann fragmentation reaction 14:475 Chiral ylide 4:125 from L-malic acid 4:125
897
Chiral ~z,~-ethylenic acetals 14:479 from C2-symmetric diols 14:479 with phenyl or alkenyl copperBF3 reagents 14:479 Chiral c~,]3-unsaturated acetals 14:478, 479 from (R, R)-(+)-N, N, N', N'tetramethyl tartaric acid diamide 14:478,479 with organo-aluminum reagents 14:478,479 Chiral ~-aldoxime-ether acetal 14:496 organocerium reagents to 14:496 Chiral cz-amino acetals 14:483 Lewis acid-mediated reaction of 14:483 with silicon-containing nucleophiles 14:483 Chiral ~-keto acetals 14:491,492 chiral tertiary alcohol from 14:491,492 from (-)-(2R,3R)-2,3-butanediol 14:491 from (-)-(2S,3S)- 1,4-dimethoxy2,3-butanediol 14:491 Chiral c~-methyl-substituted aldehyde 12:35,36 coupling reaction of 12:35,36 with chiral vinyl halide 12:35,36 Chira113-1actams 12:121 synthesis of 12:121 Chiral-o-quinodimethanes 14:502,503 asymmetric intramolecular 14:502,503 Diels-Alder reaction of 14:502, 503 with C2-symmetric acetals 14:502,503 Chiton approach 17:211 Sharpless oxidation 17:211 Chloramphenicol 29:310 biosynthesis of 29:310 c~-Chlorinating reagent 6:310 of sulloxides 6:310 Chlorination 6:310,340;19:61 Chloroacetoxylation 16:443 Pd(II)-catalysed 16:443
(~x-Chloroalkyl) boronic esters 11:409, 410 synthesis of 11:409,410 Chloroamine 11:307,308 N-Chloroamines 6:437 from N-chlorosuccinimide 6:437 Hoffmann-Loeffler photocyclization of 6:437 Chloroformate ester-induced reaction 6:477,486 ring destruction by 6:477,486 Chloromercuric method 4:233 in synthesis of 6deoxynucleosides 4:233 (Chloromethyl) zinc reagent 14:490 3-Chloroperoxybenzoic acid 22:203 N-Chlorosuccinimide 6:310 DMSO reaction with 6:310 monochlorinated sulfoxide from 6:310 N-chloroamines from 6:437 Chlorosulfonyl isocyanate 4:475,477 cycloaddition with 4:475,477 1 -acetoxy-2-methylbutadiene with 12:150,151 [2+2] cycloaddition of 4:475; 12:150,151
Chloro-tris-(triphen yphosphine) rhodium decarbonylation with 5:802 Cholesterol biosynthesis 25:722 Cholesterol oxides 24:351-398 biosynthesis of 24:358-360 Cholesterol synthesis inhibition 25:525 Chroman 1:644,645 enantioselective synthesis of 1:644,645 Chromanes 4:391 from isoprene 4:391 from phenols 4:394 in prenylation methods 4:394-396 synthesis of 4:374 Chromium (II) reagents 3:81 Cieplak's theory 29:127 in sesquiterpenoids drimane-type synthesis 29:127 Cinnamyl alcohols 27:760 polymerization of 27:760
898
Claisen rearrangement 13:29,30,135, 142,358,417,437,438,443,613 Claisen condensation 1:49,99,100,174, 243,410;19:35 ;20:740;26:1237 dual Claisen condensation 11:114 of dicarboxylic acid derivatives 11:114 with acetoacetate dianion 11:114 Claisen cyclization 9:341 Claisen disconnection 19:228 Claisen ester enolate rearrangement 10:339 Claisen orthoester rearrangement 26:72 Claisen reaction 6:36 in poitediol synthesis 6:36 [3,3]-Claisen rearrangement 10:416-426 applications of 10:416-426 asymmetric quaternization with 10:426-428 carboxylic acid anhydride variation of 4:375 Eschenmoser modification 3:230 in (+_)-9-isocyanopupukeanane synthesis 6:82,83 in (+)-africanol synthesis 6:5 in (_+)-sinularene synthesis 6:78, 79 in lactone synthesis 3:252-255 indolo [2,3-a] quinolizidines by 14:722-724 internal asymmetric induction 3:234 Ireland modification 3:77,228 of 1,5-anhydro-4,6-O-benzylidene-D-ribo-hex- 1-enitol 10:420 of allyl ester 14:738 of allyl phenyl ethers 4:368 of carbohydrate derivatives 10:416-426 of carbohydrates 3:226 of chiral allylic alcohols 10:418 of cis 2,5-disubstituted dihydrofuran 10:423,424 of dihydropyran derivative 10:425 of E (3-hydroxy- l-propenyl)-[3-
D-glucopyranose tetra acetate 10:422 ofN,O-ketene acetals 3:232 of oxygen substituted systems 3:237-248 of silyl ketene acetals 422,423 of vinyl ether derivative 10:420 of vinyl ketene acetals 10:234, 235 of xanthones 4:368,370-372 ortholactone procedure 3:236 regioselectivity of 4:368,368 Claisen rearrangement 1:43,45,78,91, 172,173,180,181,230,243,251,457, 459,471,563;8:180;11:471 ;16:260, 340,439,471,623,627,703,712; 19:229;20:66,67 ;24:47,756,758 Classical Nazarov reaction 14:612 Cleavage of olefins 1:445 with t-BuOOHg/HsIO6 1:445 with Mo (CO)6 1:445 Clemensen reduction 12:240,279,697, 698;15:197,198 Clemmensen reduction 24:205 Clemmensen-type deoxygenation 19:18 Cleomeolide 23:488,491 transformation of 23:488,491 synthesis of 23:488,491 Climacostol 30:140,162 synthesis of 30:140 C-linked glycosyl acetylenes 10:358 from glycosylhalides 10:358 Clitocybe subilludens (Omphalotus subilludens) 29:296 biosynthesis in 29:296 CNBr-induced reaction 6:472-474,476, 477,484,486,488,489,491,492,495, 496 C-Nucleosides 10:337,338,355,358, 388-394 Cobalt-stablized carbocations 3:83,84 in macrocyclization 3:83,84 coculolidene 3:456,488 synthesis of 3:477,478,488,489 Colchicine 29:364 allocolchicinoid synthesis from 29:364
899
Colchinol analogue 29:378 allocolchicinoids total synthesis of 29:378 Collins allylic oxidation 6:27 in (-)-dictyolene synthesis 6:27 Collins oxidation 1:16,83,84,210,312, 313,315,316;6:16;11:83,84;19:320, 334,467 ;22:277 ;24:7 Collins reagent 6:115,350,317,335; 16:16;22:206,222 Collins-Wege intermediate 6:78,79 in (_+)-sinularene synthesis 6:78,79 Collinusin 24:769,770 synthesis of 24:769,770 Condensation 24:198 Conformational control 11:152-158 in macrolactonization 11:152-158 Conformational effects 12:115 Conformational property 27:337 of analogs 27:336 Conformational studies 27:258-259 of (-)-o~-isoparteine 27:259 of (+)-[3-isosparteine 27:259 Conformations 27:335 of abscisic acid 27:335,337 Coniferyl alcohol 27:760 polymerization of 27:760 1,4-Conjugate addition 10:405,406 of electrophile 10:405,406 to ~,13-unsaturated carbocyclic aldimines 10:405,406 Conjugate addition 3:8;14:510;24:12, ! 88-190,744,747-749,775 Conjugated dienes 8:278 synthesis of 8:278 Conjugated ketones 2:168 octant rule for 2:168 Conj ugation-deconj ugation epimerization 12:14 Controlled crisscross annulation 13:442 Convergent lactone synthon 13:604 synthesis of 13:604 Conversion 22:135 of cortisone to cortisol 22:135 Conversion of MFA 28:333 to (+)-paraherquamide B 28:333
Conversion of PHB 28:331,335,33 l, 367367 to paraherquamide A 28:331,367 Cook 29:375 allocolchicinoids total synthesis by 29:375 Cooke's dianion 13:594 Cooxidants 19:270 Cope elimination 3:468,470,471,494, 110 Cope reaction 13:109 Cope rearrangement 1:182,236,416, 566,567;3:47,98,139,190,191,249, 372;7:216;10:236 Cope ring enlargement 12:193 Copper (I) catalyzed Grignard additions 10:180 Copper (I) trifluoromethane-sulfonate benzene complex 1:271,272 Copper acetylide 4:396,398 Copper catalyzed Grignard reaction 11:81,82 Corey asymmetric osmylation 26:1232 Corey epoxide 13:568 Corey method 11:154,157 Corey procedure 6:562 Corey reagent 14:268;19:452 Corey's oxazaborolidine catalysts 18:182 Corey-Fuchs protocol 30:43 Corey-Kim oxidation 12:338 Corey-Mukaiyama method 1:271 Corey-Myers synthesis 6:195 Corey-Nicolaou method 12:52,53 Corey's lactone 7:480-482 Cornforth's methodology 30:434 Cortisone 22:135 conversion to cortisol 22:135 p-Coumaryl alcohol 27:760 polymerization of 27:760 p-Coumaryl-hydroxy oxyagmatine 27:765 pero x idase-c atal y zed dimerization of 27:765 p-Coumaryl-hydroxyagmatine 27:765 peroxidase-catalyzed dimerization of 27:765 Coupling reactions 26:113,114,119 of secologanin 26:113,114,119
900
C-prostaglandins 16:367-368 synthesis of 16:367-368 C-pyranosides 10:340 synthesis of 10:340 Cram (l,2-syn) coupling product 12:42, 43,45,48,50,55 Cram (1,2-syn)-selective coupling reaction 12:35,36 of chiralvinyl halide 12:35,36 with A chiral-~-methylsubstituted aldehyde 12:35,36 Cram addition 16:345 of enolates 16:345 of 2-1ithiofurans 16:346 Cram rule selectivity 1:608 Cram selectivity 19:473 Cram's rule 14:482;16:350 Cram's chelation model 19:320,482 Cram's product 19:471,476 Cramer reaction 8:77,80 Cram's cyclic model 4:201,491 of 1,2-asymmetric induction 4:201 Cram-selective aldol-lactonization 14:115 Crassin 8:19-30 titanium-induced coupling 8:19-30 p-Cresyl methyl ether 6:83,84 Birch reduction of 6:83,84 Criegee rearrangement 14:128 Crimmins synthesis 12:11,12 Cross coupling reactions 16:417 intramolecular 10:163 Pd-catalyzed 10:161,162 with (Z)-tributylvinyl-stannanes 10:162 Cross relaxation rates 2:60,61 Cross-aldol reaction 12:297 of (7R, 8aS)-8-hydroxy- 8-methyl7-oxoindolizidine 12:297 Cross-aldolisation 12:289,298 Cross-Claisen condensation 11:114 Cross-condensation 30:218,219 products of 30:219 Cross-conjugated hydronaphthalene dienones photochemical 14:356 rearrangement of 14:356
C2-symmetric diols 14:469-518 chiral acetals from 14:469-518 C2-symmetric ketene acetal 14:505 asymmetric cycloaddition of 14:505 to 3-formyl chromone 14:505 Crossed Aldol reaction 4:328,329 asymmetric induction in 4:328,329 Crossed Cannizzaro reaction 4:17,135 Crossed Wittig reaction 4:570 Crossed-Aldol condensation 1:596-603 diastereoselective 1:596-603 Johnson-Yamamoto mechanism 1:600 trans-Crotonamide 8:156 cis-Crotonamide 8:156,157 Crotonates 8:410-412,427 trans-Crotonates 8:141,147,155,157 cis-Crotonates 8:155-157 synthesis of 8:155-157 Crotonyl boronate addition 1:527 Crotyl halide 12:172 in zinc dust 12:172 with 4-acetoxy 13-1actam 12:172 Crotylborane reagent 12:36 Crotylboration 8:477 (-)-(E)-Crotyldiisopinocamphenyl borane 18:280,281 [E]-Crotylpotassium 8:477 [Z]-Crotylpotassium 8:477 Crown ether effect 11:234 Crystallization- induced 13:76 asymmetric transformation 13:76 C-Sucrose 11:469,470 synthesis of 11:469,470 CuI-tributylphosphine complex 4:556, 557 tandem Michael addition with 4:556,557 Cuprate 1:456,457,459,460 Curtius degradation 19:145 Curtius reaction 12:448,458 Curtius rearrangement 1:6,51,309,637, 638;19:68,79;21:435,746;26:1237 Curtius-type reaction 13:95
901 Cyanide versus isocyanide formation 3:207 Cyano trapping 1:105 2-Cyano-azadiene Diels-Alder reaction 16:458 a-Cyanobenzyl alkyl ether 14:473 synthesis of 14:473 Cyanoborohydride 8:205 Cyanogen bromide 2:34 fragmentation of glucoamylase 234 Cyanohydrin 8: 198 cyclization of 8: 198 synthesis of 8:225,226 Cyanohydrin ether 8: I77 alkylation of 8: 177 cyclization of 8:178 Cyantions 1:6 I2,6 13 diastereoselective 1:612,613 of acetals 1%12,613 Cyclic dienes 8:14 1 Cyclic ene-dione acceptors 4:709,71 1 in Michael reaction 4:707-709 Cyclic enones 14:502 [2+2]photocycloaddition of 14:502 with chiral a,P-unsaturated acetals 14502 Cyclic halo ether compounds 19:4 1 1-461 from marine origin 19:4 I 1-461 synthesis of 19:4 I 1-46I Cyclic hexadepsipeptides 13533 Cyclic hydroxamic acid 27: 199 a-hydroxylation of 27: 199 Cyclic ketones 6:3 13-315,332,333 synthesis of 6:313-315,332,333 Cyclic peroxides 5:353-355 Cyclic steroidal glycosides 15:59,60 Cyclic sulfides 8:205 Cyclic systems 6:33-38 synthesis by modifications of 6~3.1-38 de t i o w synthesis of 63.3 Cyclic P-keto esters 1:697-701 reduction with yeast 1:697-701 Cyclic-Cram diastereoselectivity 12:297
Cyclisation 30:2 13,462,717 of 3s isomer of 2,3-epoxy-2,3dihydrosqualene 30:7 17 of squalene 30:7 17 of triterpenoids 30:7 17 using TFA-water mixture 30:462 Cyclitol derivatives 7: 156, I57 Cyclization 11:22 1,222 (+)-(4R)-a-terpinyl from 11:221,222 acyliminium-mediated 10: I25 amide iminium ion 10:87 asymmetric 10:631-633 azido-olefin 13:447,448 bicyclic keto ester from 14509 by C-C bond formation 10:218-231 by C-0 bond formation 10:202 by diphenyl phosphoryl azide 10:641,644,652,656,657 by sodium bistrimethylsilylamide 6540 catalytic 8:278 Dieckmann 13:445 enzymatically controlled 11:287 in silver (I) triflate 12:8 1 intramolecular 1053 1-633; 11:253,254; 12: 156 iodotrimethylsilane mediated 11:109 Lewis acid mediated 10:87 ligase catalyxd 14:304,305 mechanism of 6:314,315;7:33533 8,358-360 of (-)-(3R)-linalyldiphosphate 11:22 1,222 of (L)-glutamic acid 6:438-440 of acyclic nucleoside derivative 10588,592 of ally1 glycidyl ether 10588, 589 of a-mono-alkoxylated piperaxinediones 12:90 of cyanohydrin ethers 8:194 of epoxy alcohol 10599,600 of epoxy allylic ether 10590, 59 I of glucose 11:219 of hexapeptide 10:289,290
902
of ketoesters 4:328-330 of lycopene 7:334-354 of neurosporene 7:334-354 of nitroketone 6:447,448 of oligoribonucleotides 14:304,305 of vinyl sulfoxides 10:673-676 of vinyl sulfoximines 10:679 of ~-diazo [3-keto ester acetals 14:509 oxetane ring formation by 10:588,589 oxetanocin A synthesis by 10:588-592 palladium catalysed 1:258 reductive 8:278 regioselectivity of 6:540 Rh (II)-catalyzed 14:509 stereochemistry of 7:338-354 stereoselectivity of 6:540 transannular 13:440 via S N 2 displacement 11:253, 254 with copper (II) perchlorate 12:85 with diphenyl phosphoryl azide 10:289,290 with Nicolaou reagent 10:121, 122 with pyridinium chlorochromate 11:93,94 Cyclization reaction 6:15,43,44 [2+2] cycloadditions 6:15,43,44 diastereoselective 14:506,507 in (+)-A 9(12) capnellene synthesis 6:43,44 in cadinane synthesis 6:15 in elemane synthesis 6:15 in germacrane synthesis 6:15 of 6-octen-l-al 14:506,507 Rh(I) catalyzed 14:506,507 Cyclized branched oligoribonucleotides 14:486,489 [2+3]-Cycloaddition 3:469 4-oxo-erythrinans by 3:469 [6+4]-Cycloaddition 1:571 intramolecular 1:571 of cyclopentadiene with tropone 1:570
of dienes to tropone 1:569-571 of 2-alkenyltropolones 5:799, 800 [2+2]-Cycloaddition 1:263,343;4:475; 8:45,185,207;11:15-20,45-47; 12:116,150-152,160,161,173,193, 416;15:266;16:127,470,732,733 carbocyclic oxetanocins synthesis by 10:610-616 enantioselective 10:610-616 in homoerythrinan synthesis 3:481,478 of allene 16:127 photochemical 16:125,469 with dichloroketene 13:6,36 synthesis of quinoline skeleton 3:385-397 [4+2]-Cycloaddition 1:282,323,420, 465,8:45,185,207;11:11,13,14,16, 260-267 ;16:4,444,493,732; 19:108-109,148,221,227 acid catalyzed 4:4 cycloaldolization 4:4,11,17,18, 22,23 diasteroselective 12:424,425 high pressure Eu (fod)3-mediated 4:121,143 in (+)-A -9(12) capnellene synthesis 6:43,44 in lincosamine synthesis 4:154 in purpurosamine C synthesis 4:115 of 2-alkenyltropolones 5:799 of 3-[(1S)-2-exo-alkoxy- 1apocamphanecarbonyl]-2oxazolones 12:424,425 of s-amino aldehydes 4:111 of kojic acid 5:799 reverse stereoselectivity of 4:122 to dialkyl azodicarboxylates 12:424,425 transannular 5:796,797 [3+4]-Cycloaddition 1:378,522,523 1,3-Cycloaddition 1:448,449 [8+2]-Cycloaddition 1:568 [6+3]-Cycloaddition 1:569 [4+4]-Cycloaddition 11:17 [6~+4~]-Cycloaddition 12:238
903
Cycloaddition 16:7,47 1,3-dipolar 1:247-250 asymmetric 1:371-375;11:300 by 3-hydroxy- l-arylthiobutene 4:477 by chlorosulfonyl isocyanate 4:475 E-exo-transition state 1:370,371 enolate induced 1:502-503 intramolecular [3+2] 1:247-250 intramolecular [4+1 ] 1:247-250 intramolecular nitrile oxide [INOC] 1:477,480,481 ionic 5:793 lanthanide catalyzed 1:413,415 MgBr2 mediated 1:474 Ni (O)-catalysed intramolecular 3:78,79 of (N-acryloyl) bornan- 10,2sultam 11:307,308 of alkene 11:468 of levoglucosenone 14:270,271 of olefinic ketone 1:693 photochemical [2+2] 1:548 stereoselection 1:370,371 Ticl4-catalyzed 11:307,308 with bisketene 4:349 with cyclopentadiene 11:307,308 with ethoxycarbonyl formontrile oxide 11:468 with unactivated olefins 1:338 [2+2]-Cycloaddition 24:190,191 of dichloroketone 24:190,191 [5+2]-Cycloaddition 8:160-163,16:552, 553;12:260,261 [3+2]-Cycloaddition 8:402,19:66,78, 80,174,367 of 2-azaallyl fragments 1:324 of azomethine 8:402 of azomethine ylide 19:80 intramolecular 19:367 stereospecific 19:367 Cycloaddition processes 12:250-261 for tigliane ring system 12:250-261 [3+2]-Cycloaddition reaction 12:155 of nitrone 12:155 to benzyl crotonate 12:155
Cycloaddition reaction 14:502-505,747, 19:226 diastereoselective 14:502-505 with 1-trimethyl silyloxybutadiene 14:747 of quinone monoketals 5:796, 797 [2+2 ]-C ycl oadd iti o n- fragm en tati o n 12:194,195 [4rt+2rt]-Cycloadditions 1:566-571 intramolecular tropone-olefin 1:568 inverse electron demand 1:566 with tropone as diene 1:566-571 Cycloadduct 12:425 chiral synthon of 2-amino alcohol from 12:425
trans-4-methoxy-2-oxazolidinone
from 12:425 [5+2]-Cycloadducts 16:555-559 [4+2]-Cycloadducts 16:732 [2+2]Cyclobutane formation 10:611, 613 Cyclobutanes 16:553 protic acid rearrangement of 16:553 rearrangements of 16:554 Cyclobutanone 10:618 oxaspiropentane rearrangement by 10:618 Cyclobutanone-ring expansion 3:23,24 Cyclocondensation 4:130,145 and threo-selectivity 4:130,145 Lewis acid catalyzed 11:446-451 Mg Brz-catalyzed 11:451 MgBr2 catalyzed 1:415,417 with Ce(OAc)3-BF3.OEt2 1:420,421 with Danishefsky's diene 4:122,130 with Eu FOD 1:420,421 with L-serinal 4:122 with N, O-protected s-amino aldehyde 4:130 with silyloxydienes 4:113 Cyclodecadienone 8:247 by [3+3]-Oxy-Cope rearrangement 8:247
904
by Diels-Alder reaction 8:249 photocycloaddition 8:250 Cyclodimerization 4:92,93 with DEPC 4:92,93 of tetrahydroisoquinoline precursors 6:495 Cyclofunctionalization 6:427,428 of ethylurethanes 6:427,428 with phenylselenyl chloride 6:427,428 Cyclohemiacetals 27:196 synthesis of 27:197 Cycloheptenone enolate 6:29,30 in perforenone synthesis 6:29,30 Robinson annulation of 6:29,30 1,4-Cyclohexadiene 27:343 of boat-boat inversion potential 27:343 Cyclohexane ring system 6:5,6,29,30 annulaton of 6:5,6,29,30 1,2-Cyclohexanediones 12:376,377 bis-Fischer indolization of 12:376,377 Cyclohexanone 8;36;30:141 aromatization of 14:637,638 by chiral lithium amides 14:571, 572 kinetic deprotonation of 14:571,572 monoacylation of 30:141 prochiral 4-substituted 14:571, 572 Cyclohexanone aldehyde 6:61 bromochamigerene from 6:61 spiroannulation of 6:61 spiro[5.5] undecenone derivatives from 6:61 2-Cyclohexen- 1-one 11:337,338 aldols from 11:337,338 kinetic deprotonation 11:337,338 with 4-pentenal 11:337,338 Cyclohexene derivatives 4:581 synthesis of 4:581 Cyclohexene imides 12:378 arcyriaflavin A from 12:378 bis-2-chlorophenylhydrazones from 12:379
N-methylarcyriaflavin A from 12:378 trans-Cyclohexenecarboxylic acid 11:340,341 by Diels-Alder addition 11:340,341 from (E)-crotonic acid 11:340,341 from butadiene 11:340,341 deprotonation of 14:658 with lithium diisopropyl amide 14:658 Cycloisomerization 8:297 of cis, cis-3-carboxymuconic acid 8:297 Cyclo-octanoid terpenes 6:33-36 synthesis of 6:33-36 Cyclopentane annulation 13:6,16 Cyclopentane ring system 6:6-8,30,31 annulation of 6:6-8,30,31 Cyclopentanol 14:647 formation of 14:647 in 8-alkoxy ketones 14:647 ring expansion of 8:245 Cyclopentanone 6:428,429 1-piperidenines from 6:428,429 Cyclopentene annulation 13:14 Cyclopropanation 14:489-491 diastereoselective 14:489-491 exo 1:252,253 intramolecular 16:222 of allylic alcohol-acetal 14:490,491 of diazo ketones 3:39,40 of ten-membered enones 8:179 of unsaturated acetal 14:490 with Me3S (O)I-NaH 8:186 with oxysulfurane 8:183 Cyclopropane ring opening 1:250-253 Cyclopropanone sliding reaction 6:37,48 (+)-A-9(lZ)-capnellene from 6:48 in (+)-dactylol formation 6:237 in eight-membered marine compounds 6:37 Cyclopropyl imine 1:250,251,296 acid catalysed rearrangement 1:250,251,296 Cyclopropyl ketones 2:168,169
905
Cyclopropyl-carbinol rearrangement 3:23 Cycloreversion 4:609 Cycopentannulation 1:551,552 Cytochrome P450 27:346 by hydroxylation 27:346 Cytochrome P450 enzymes 27:348 oxidation of 27:348 D-(-)-DIPT 19:490 D-(+)-DIPT 19:445,480,490 24-epi-D2 30:490 synthesis of 30:490 24-epi-D6 30:490 synthesis of 30:490 Dacryhainansterone 29:19 as synthetic ecdysteroid analogues 29:19 (+)-Dactylol 6:37 cyclopropanone sliding reaction in 6:37 DAH 30:444,448,473 precursor of 30:444 stereocontrolled total synthesis of 30:473 synthesis of 30:448 DAH ammonium salt 30:455 by spiroketal glycosides 30:455 DAHP 30:420,431,472 synthesis of 30:472 Dakin reaction 9:341 Danishefsky synthesis 12:12,13,15 of mitomycins 13:443 of avermectin A~a 12:12,13,15 Danishefsky's diene 1:460,474;4:122, 130,132;8:207;13:565;14:18, 636-638;16:474,496,654 Danishefsky's KDO synthesis 30:461 Danishefsky's pyran synthesis 1:460, 407 Dansylation 9:547,549 D-Arabinose-5-phosphate 30:429 irreversible aldol reaction of 30:429 Darzens reaction 17:612 Darzens-Nenitzescu condensation 19:235 DCC-HOSu procedure 6:407,409
DDQ (2,3-dichloro-4,5-dicyanobenzoquinone) 11:156,165 De novo synthesis 25:128,129,294,300, 329,401,659,661,662 of bioflavours 25:125 De novo-biosynthesis 25:374 Deacetylation 1:10 N-Dealkylation 27:754 and electron transfer 27:754 O-Dealkylation 27:754 and electron transfer 27:754 Deaminated Neu5Ac analogues 30:427 preparation of 30:427 Deamination 1:681 of (R)-2-aminohexadecanoic acid 1:681 Debenzylation 11:253,254;19:110,115; 30:441 Debenzylidenation 12:347 by Hanessian procedure 12:347 Deboronation 11:412,413 Debromination 4:336,337 Debromoaplysiatoxin 18:295,297; 19:219 (2E,4Z)-2,4-Decadienal 10:151 (2E,4E)-2,4-Decadienal 10:151,155 trans-Decahydro-5,8a-dimethyl- 1,6naphthalenedione derivatives 10:461 (+)-trans-Decahydroquinoline 219A 19:4,7 Decahydroquinoline-type dartpoison frog synthesis 29:419 by Stereodivergent process 29:419 Decarboalkoxylative cyclization 14:720-722 alkaline 14:720-722 indolo-[2,3-(z] quinolizidines from 14:720-722 stereochemical course of 14:720-722 Decarbomethoxylation 3:473 with MgC12/DMSO 3:473 with CaCIz/DMSO 3:475 Decarbonylation 3:308,309 Rh (I)-catalysed 3:308,309 with Wilkinson's catalyst 11:263
906
with chloro-tris-(triphenyphosphine) rhodium 5:802 Decarbonylation-iminium ion cyclization 4:38,39 Decarboxylation 16:371 of 13-keto ester 16:371 of anthrones 11:121 of 2-methyl-3-buten-2-yl acetate 11:130 Pd-catalyzed 11:143,144 of vinylogous 13-keto acid 14:678-681 Decarboxylative condensation 11:195 Deconjugation 1:464,465 Deconjugative alkylation 4:38 Decumbenine B 21:735 synthesis of 21:735 Decyanation 6:431-433 Defluorination 5:453,455,477 of 2-fluroestradiol 5:477,453,455 Degalactosylation 7:55 Degradation 9:31,32 of aureol 9:31,32 of enantio-sigmosceptrellin-A 9:28,29 of geraniol 7:104,105,116 of nerol 7:105 of ~-pinene 7:106 of S-HPOTE 27:71 of 13S-HPOTE 27:71 Degradation reaction 21:502 Dehomologation 12:95 Dehydration 10:124 with Burgess reagent 10:124 of N-monosubsituted formamides 12:113 of phenyl sulfone derivative 30:486 Dehydrobromination 11:341,342 Dehydrobruceantin 7:374 Dehydrodigalloyl group 23:397,399 in oligomers 23:399 Dehydrogenase enzymes 22:4 Dehydrogenation 2:3,4 in CI(NO) mass spectra 2:3,4 of amines 4:54 with CMD 4:85 with DDQ 1:8,9,59
with other oxidants 4:85 with palladium black catalyzed 14:763 with p-toluene sulfinyl chloride 4:54 with selenium reagents 14:440 with sulfur catalysis 14:763 Dehydrosulfinylation 6:342 De-isopropylidenation 4:200,201 Deketalization 14:678,679 Delocalised allylic cation 30:547 formation of 30:547 DeMayo reaction 3:74,75,102,103 Demercuration 1:671,672 with sodium borohydride 1:671,672 Demethoxycarbonylation 10:308,309 by Welch procedure 10:308,309 Demethylation 1:8,9 Dendrobates alkaloids synthesis 29:433-436 aldehydes synthesis in 29:435 aldol-type cyclization reaction in 29:436 alkyl group installation in 29:43 decahydroquinoline type of 29:433 stereochemical course of 29:434 De-N-protection 11:270 via hydrogenolysis 11:270 De-O-Acetylation 14:230,232 De-O-Benzylation 12:37,38,52 6-Deoxocastasterone 25:415,424 C6 oxidation of 25:415,424 3-Deoxy-2-ulosonic acid 30:419,420, 434,460 stereoselective synthesis of 30:434 6-Deoxy-5-enohexopyranoside 10:510 Ferrier reaction of 10:510 6-Deoxy-6-cobalt(III)-dimethylglyoximatopyridine 30:449 photolysis of 30:449 3-Deoxy-D-arabino-heptulosonic acid 7-phosphate 30:472 synthesis of 30:472 3-Deoxy-D-erythro-hexulosonic acid 30:437
907
by non chelate-controlled process 30:437 3-Deoxy-D-glycero-D-galactononulosonic acid 30:427 preparation of 30:427 Deoxygenation 19:516 of tert-alcohol 19:516 with AIBN 19:516 with Bu3SnH 19:516 with PBr3 1:391,392 of D-glucose 11:219 by zinc-copper couple 4:424 by zinc-dust 4:424 of ascorbic acid 4:420-423 in steroid moiety synthesis 30:486 9-Deoxygoniopypyrone 19:463,19:497 2-Deoxy-KDO 30:456 hydrogenation in 30:456 transformation of 30:456 2-Deoxy-KDO synthesis 30:470 concept of 30:470 Deoxylapachol 29:736 biosynthesis of 29:736 (-)-Deoxypodophyllotoxin 24:767 synthesis of 24:767 Deoxysikkimotoxin 24:767 asymmetric synthesis of 24:768 synthesis of 24:767 2-Deoxy-ulosonic acid analogues 30:467 for synthesis 30:467 3-Deoxy-ulosonic acids 30:435,451 construction of 30:451 synthesis of 30:435 3-Deoxy-s-D-arabino-2-heptulosonic acid (DHA) 30:420,439 from 1,4-cyclic sulfate and Darabinose 30:439 preparation of 30:439 1-(2-Deo xy-o~-D-ribo-he x op yran o sy1) cytosine cis-principle 4:586,587 endo-rule 4:587 in biogenesis 4:615-617 intermolecular 4:587-595 intramolecular 4:595-603 inverse electron demand 4:579, 580,604,605 lysergic acid by 4:504,605
manaomycin A by 4:591-593, 609 mechanism of 4:579,580 monomorine I by 4:606 nanaomycin d by 4:591-593 nepetalactone by 4:604,605 of acylnitroso 4:606 oxazoles in 4:604 palitantin by 4:588-590 prostaglandin by 4:607 pumiliotoxin by 4:584,585 regiochemistry of 4:584-586 retro 4:609-615 solanapyrone 4:598,599 stereochemistry of 4:586,587 stereochemistry of cycloaddition 4:122,123 terramycin 4:609 tetrazines in 4:604 triazines in 4:604 triquinanes by 4:588 vernolepin by 4:584,585 volume of activation 4:112 with heterodiene systems 4:583 with ketenacetals 4:357 with modified cyclohexadienes 4:583 with N-sulfinyl dienophile 4:356 with o-quino demethone 4:583, 584 with o~-amino aldehydes 4:120 13-santalene by 4:607,608 2-Deoxy-13-Neu5Ac 30:468 approach to 30:468 4-epi-2-Deoxy-~3-Neu5Ac 30:468 approach to 30:468 DEPC 4:92,93 cyclodimerization with 4:92,93 Dependent aldolases 30:423 synthesis of 30:423 Dephenyl thiolation 14:306 Deprotection 4:282,283 of oligonucleotides 4:282,283 of triethyl silyl group 4:533 with tetra-N-butylammonium fluoride 6:119-122 Deprotection of alcohol 1:558 with TMSC1/NaI 1:558
908 Deprotonation 10:425 LDA-mediated 10:425 of allylic ester 10:425 of 3-C-methyl-3-deoxy-2-ulose derivative 10:414,415 with N-lithio-2,2,6,6tetramethyl-piperidine 10:414, 415 asymmetric 11:241,242 azabicyclic ketone 11:241,242 DER peptides 30:816 structural modifications of 30:816 Desilylation 8:263 with HF-pyridine 8:263 of N-(trimethylsilyl) methyl iminium ions 1:325,328 with cesium fluoride 1:249 D6sir6 and Prandi 29:455 carbafuranose synthesis by 29:455 Desoxyribonucleotides synthesis 26:924 Dess-Martin oxidation 19:370-371 ; 26:1244 Dess-Martin periodinate 19:357 Desulfonylation 19:77;11:349 Desulfurization 21:426 Dethioacetalization 12:348 Detritylation 4:276-279,282,284 D-Glucose aldehyde 30:443 role in aldol reaction 30:443 hydrogenation of 30:443 cyclization of 30:443 D-Glyceraldehyde derived allylic alcohols 10:436,437 Johnson-Claisen rearrangement of 10:436,437 2,4-Diacetamido-2,4,6-trideoxyhexopiranoses 30:434 synthesis of 30:434 condensation of 30:434 3,4-Dialkoxyfurans 12:19,20 Diels-Alder cycloaddition 12:19,20 with alkyl coumalates 12:19,20 Dialkyl azodicarboxylates [4+4] cycloaddition 12:424,425
to 3-[(1S)-2-exo-alkoxy-1apocamphanecarbonyl]2-oxazolones 12:424,425 Dialkylation 6:332,341 Dialkylboranes 9:366 Dianion 11:284,285 alkylation of 11:284,285 condensation of 12:9,10 from 4-[tert-butyldiphenylsilyl)oxy]-2-(tributyl-stannyl)(E)-2-buten- 1-ol 12:9,10 of FAMSO 6:323-325 stereoselective 11:284,285 with 1-TMS-2-pentyne 11:284, 285 with ~,13-epoxy cyclohexanone derivative 12:9,10 Dianion aldol condensation 12:69 2,6-Diaryl-3,7-dioxabicyclo [3.3.0]octanes 24:755-762 synthesis of 24:755-762 Dias synthesis 30:44-46 of (-)-pironetin 30:44-46 Diastereoconversion 12:479 Diastereodifferentiating isomerization 14:510 4-hydroxy-2-cyclopentenone acetal from 14:510 of meso-3,4-epoxycyclopentanone 14:510 Diastereofacial selection 13:62-70 Diastereofacial selectivity 4:172,173 of chiral epoxidizing agent 4:172,173 Diastereolselective alkylations 1:613-616 Diastereolselective cyclopropanations 1:629-632 of ~,13-unsaturated acetals 1:629-632 Diastereomeric resolution 1:585-588 Diastereoselection 10:215 1,2-Diastereoselection 4:443,448,451, 472,474 Diastereoselective addition 14:508,509 of chiral aryl Grignard reagents 14:508,509 to carbonyl compounds 14:508, 509
909
of Grignard reagents 1:62 l to ketals 1:621 Diastereoselective aldol reaction 30:431 of pyruvate 30:431 Diastereoselective alkylation 17:324 Diastereoselective cyanation 14:473 Diastereoselective cyclizations 1:590,591 Diastereoselective cyclopropanation 6:544,545 Diastereoselective eliminative cleavages 1:618,619 Diastereoselective halolactonization 1:620,627-629 Diastereoselective Michael addition 6:86,87,286 Diastereoselective reduction 1:595 Johnson-Yamamoto rationale 1:595 of carbonyls 1:622 Diastereoselective routes 29:471 to carbaaldopyranoses synthesis 29:471 Diastereoselective synthesis 12:479-481 of (3R,4R)-staine 12:479-481 of 2(o~-hydroxyalkyl) piperidines 12:453 of 4o~-aryldecahydroisoquinolines 12:456-463 of 6-hydroxy-4o~-phenyldecahydro 12:457 of B/C-trans-morphinan 12:464-471 of octahydroisoquinolines 12:457 of piperidine derivatives 12:471 of pyrrolidine derivatives 12:471 of methylphosphonate 13:276-278 of phosphorothioate 13:276 Diastereoselective synthesis 27:208 of Blepharin 27:188,208,209 Diastereoselectivity 11:359;16:372 Diastereotopic groups 17:481 Diazidation 10:465 Diazoketone 1:492 cyclization of 1:492 from adenosine 10:593-595
preparation of 10:593-595 Wolff rearrangement of 10:593-595 Diazoketone insertion 1:555,556,564 copper mediated 1:555,556,564 cyclization 1:492 Diazomethane 1:404,405,439 esterification of 1:404,405 methylation with 1:435 ring expansion with 3:12 sugar aglycone linkage cleavage by 7:155,156 Diazotization 3:325,226 DIBAH reduction 6:428;14:634;19:172 DIBAL 1:177;14:529,530;19:318 reduction with 6:285,286,293, 288,294,299,549,550;11:432, 457;13:456,464,465 ;20:67 DIBAL reduction 21:391 (DIBAL-H) reduction 10:428,429 of o~,]3-unsaturated ester 10:428,429 Dibenzocyclooctadiene 24:775-781 derivatives of 24:775-781 synthesis of 24:775-781 Dibenzylbutyrolactone yatein 29:369, 371,380 steganes synthesis from 29:369, 371,380 Dibromide synthesis 29:482,483 by Rassu 29:482,483 Dibutyltin oxide 1:274 for stannoxane preparation 1:274 Di-C-alkylation 10:413 of D-mannose derivative 10:413 [3-Dicarbonyl 10:343-348 Dicarbonyl coupling 3:99 by Mukaiyama procedure 3:99 intramolecular 11:345,364-467 with TiC13/LAH 3:80,81 with TiC13/Zn-Cu 3:80,81 o~-Dicarbonyls 8:262 synthesis of 8:262 Dichlorocarbene addition 10:413 Dichloroketene 13:6 [2+2]cycloaddition with 13:6 (Dichloromethyl) boronic ester 11:409, 410
910
synthesis of 11:409,410 (Dichloromethyl) lithium 11:410 Dichloromethylenation 3:223 Dichloromethylphosphine 13:276 Dictyosterol 30:505,507 synthesis of 30:507 Dicyclohexylborane 4:116,117 Dicyclohexylcarbodiimide 12:328 Dieckmann condensation 3:191,289, 338,339;8:192,284,293 of ethyl 2-[ 1-(2-ethoxycarbonylmethyl) piperidinyl]-proponoate 12:284 of ethyl 4-[ 1-(2-ethoxycarbonyl pyrrolidinyl)]butyrate 12:293 Dieckmann cyclization 1:183,340; 10:328,408,410,411;12:126,147, 279,308,445;13:25,26,117,131-133; 14:34,35 ;24:3,33-35,42,43 Diels Alder dimerization 2:122,128 Diels-Alder adduct 6:84,85,125,340, 451;4:388,389 endo Diels-Alder adduct 6:33,34 in (_+)-precapnelladiene synthesis 6:33,34 Diels-Alder chemistry 16:9 of bicyclic intermediate 16:9 Diels-Alder cyclisation strategy 30:220 Diels-Alder equivalents 3:4 retro-Diels-Alder reaction 26:111,138 Diels-Alder reactions 20:769,770; 21:211,434;24:8-10,27-31,195196,762,763,766,76826:172;30:661 asymmetric 12:26,27;24:768 asymmetric intramolecular 14:502,503 atomic orbital coefficients in 4:585,586 betaenone B by 4:601,602 cadinane by 4:584,585 (+)-capnellene by 4:588 cholesterol by 4:587 (+)-coriolin by 4:588 coronafacic acid 4:590,591, 596,597 cycloaddition 16:7,219,245,422 diastereoelectivity of 4:441 dienes in 4:581-584 dienophiles in 4:584
diplodiatoxin by 4:500-602 effect of Lewis acids 4:586 Eu (fod)3-mediated 4:121,122, 143 exo versus endo transition state 1:373-374 facial selectivity in 10:351 for bicyclic compounds 8:410 frenolicin by 4:591,592,594,609 gephyrotoxin 223AB by 4:606 hetero 1:478 heterodienes in 4:583 heterodienophiles 4:112,583 high pressure 4:112,121,122 (+)-hirsutene by 4:588 imino 1:288,289;4:604,605 iminodienophile in 4:604,605 in (-F)-A9(12) capnellene synthesis 6:46 in (+_)-12-deoxy-scalaradial 6:58 in anthracyclinone synthesis 1:502,503 in synthesis of quinolines 3:387397 intermolecular 12:19,20,380; 10:409;12:19,20,380;16:4,24 456 intramolecular 1:71,347,478, 479;3:79,80;8:403-406;10:51, 52,155,156;11:11,92,93,99-108; 12:253;13:108,117-141,144, 149;14:735;19:11,464 intramolecular imino 1:385-382 intramolecular nitroso 1:379381,383 inverse electron demand 3:311; 16:433 Lewis-acid catalyzed 8:141 ; 12:26,27 non-catalyzed reaction 8:142 N-sulfinyl cycloaddition 22,23 odd carbon equivalent 3:419 of 1,3-butadiene 19:68 of 3,4-dialkoxyfurans amides 12:19,20 of amine 16:474 of butadiene 11:340,341 of chiral 1;3-dieneacylnitroso 19:11
911
of chiral o-quinodimethanes 14:502,503 of daunosamine derivative 10:375 of dimethyl acetylenedicarboxylate 12:379,380 of enal 19:66 of enantiomeric tetraenic acid derivative 10:409 of enedione 16:28,34 of furan 19:366 of furan dienes 12:253 of imines 3:55 of isoprene 19:226 of levoglucosenone 14:270,271 of methyl-(E)-3-acetoxyacrylate 11:306,307 of N-carbomethoxy pyrrole 19:77 of N-furfuryl-[3-chloroacryl amides 12:19,20 of N-substituted pyrroles 19:77, 226 of optically active nitroolefin 19:144 of orthoquinodimethane 11:92, 93 of perezone 5:768 of pyranose diene 10:351 ofpyridyl dienophile 19:75 of styrene 16:555 precursor of 16:5,261 regioselectivity 12:16,17 retro-Diels-Alder reaction 14:821,822 stereoselectivity 12:16,17 stereospecific 19:6 transition state of 16:5 with (E)-crotonic acid 11:340, 341 with 2-azaallyl anions 1:347 with acetal 14:502,503 with his (nitrophenyl) butadiene 12:379,380 with butadiene 11:356,357 with Danishefsky diene 16:10; 19:144, 208 with doubly activated butadienes 3:465
with isoprene 11:306,307 with ketoester 19:226 with methyl vinyl ketone 19:208 with nitroso compounds 1:359392;12:16,17,250,253,416 with ~-quinonediimide 3:322323 Diene dimerization 3:107 Ni(O)-catalysed 3:107 Diene isomerization 1:447,448 Diene synthesis 6:308 Diene-carbenoid addition 3:49 1,3-Dienes 8:278,280 cyclization of 8:278,280 palladium catalyzed 8:280 Dienes 4:525 formation by reductive elimination 4:525 c~-Dienes 3:38,39 cyclopenthesis from 3:38,39 ~-Dienes 3:38,39 synthesis of 3:38,39 Dienol disilyl ethers 12:172 Lewis acid cataylzed 12:172 with 4-acetoxy-[3-1actam 12:172 Dienone-phenol rearrangement 2:253, 615,625,628;19:406 Dienophiles 12:17 from L-ascorbic acid derivatives 12:17 synthesis of 12:17 in Diels-Alder reactions 4:583 Diethyl amino (di-t-butoxy) phosphine 14:305 Diethyl phosphorocyanidate (DEPC) 4:83 Diethylaluminum cyanide 3:213 Diff Quick reagent 30:596 co,co'-Dihalides 4:560-563 l,co-Dihaloalkanes 6:313,314 ketones from 6:313,314 Dihalomethylithiation insertion 26:1221 matteson method for 26:1221 Dihydrodiconiferyl alcohol 27:760 polymerization of 27:760 Dihydronapthalenes 24:743,744,765 from oxidative coupling
912 24:743,744 synthesis of 24:765 Dihydroxylation 11:423,424 Diisobutylaliminium hydride 1:523, 324,353;4:589,590 Diisobutylaluminium 6:115 Diisobutylaluminum hydride-Nbutyllithium "ATE" complex 14:595 Dilithium (cyano) dimethyl cuprate 11:361 Dilithium (cyano) divinyl cuprate 11:360,361 DIMBoA 27:213,214 in tritrophic interaction 27:213, 214 2-(4,5-Dimethoxy-2-nitrobenzyl)20-hydroxyecdysone 29:19 as synthetic ecdysteroid analogues 29:19 3,4-Dimethoxyphenylacetone 30:219 condensation of 30:214 reactions of 30:219 10,13-Dimethyl-9-tetradecen- 1-ol 26:66 hydrogenation of 26:66 c~-Dimethylation 6:8 in (+)-brasilenol synthesis 6:8 Dimethylchlorosulfonium chloride 9:526 Dimethylsulfoxonum methylide 6:550, 551 Dimethylsulphoxide 27:512 CH3SOCH2 from 27:512 9,13-Dimethyltetradecanoic acid 26:66 total synthesis of 26:66 10,13-Dimethyltetradecanoic acid 26:67 total synthesis of 26:67 Dimsyl sodium 6:482,492,493 DIOP 13:72 Dioxepinooxindole ring system 28:360 construction of 28:360 Dioxygenation 9:560,561,566,567,570, 573,575 R-Dioxygenation 9:574,575 Dipeptide 26:1224 panek's synthesis of 26:1224 Diphenyl phosphane chloride 9:524 Diphenyl phosphorazidate (DPPA) 4:83 Diphenylphosphoryl azide 10:289,290, 641,644,645,652,656,657
Diphosgene 12:113 Dipolar [3+2]cycloaddition 19:155 1,3-Dipolar addition 1:230,231,291 Dipolar cycloaddition 13:84-86;19:42 intramolecular 13:84-86;19:42 of methyl acrylate 19:309 of alkenes 16:463 of nitrile oxide 16:464 to 3-oxidopyrazinium 10:135 1,3-Dipolar cycloaddition 1:227,278, 284,285,324- 344 ;4:435;10:65,66, 138,139,215,216,11:238-241,264, 283 [3+2]-Dipolar cycloaddition 13:191,500 DIPT 4:172-174,179,186,187 Diradical trapping 3:20 Direct cis-hydroxylation 14:183 Directed hydromagnesiation 10:29,30 Directed-aldol condensation 15:15 Dirhodium tetrakis (trifluoroacetate) 10:210 Discodermolide 30:3,4,5,6,10-12, 13-19,17,19-21,22-26 Marshall's synthesis of 30:19-22 Myles' s synthesis of 30:10-12 Paterson's synthesis of 30:22-26 Schreiber' s synthesis of 30:6-10 Smith' s synthesis of 30:13-19 synthetic routes of 30:3 total synthesis of 30:5,13 Discriminative functionalization 10:415 in hexopyranoses 10:415 of geminal dimethyl groups 10:415 Disiamyl borane (bis(3-methyl-2-butyl) borane 14:183 Disiamylborane 4:116,117 Dissymmetrization 19:45 enzymatic 19:45 of meso compound 19:45 ~,~'-Disubstituted 3-piperidinol alkaloids 29:420 prosafrinine/iso-6-cassine synthesis of 29:425 stereochemical control of 29:422 synthesis of 29:421 cis-Disubstituted butyrolactones 24:751,753
913
by Stobbe condensation 24:751 Disulfide bond 2:28,30 Diterpenes 24:196-202,284,799;27:830 reduction of 27:830 synthesis of 24:197-202 Diterpenes,bioactive 29:169 stereoselective synthesis of 29:169
synthesis of 29:169 1,3-Dithialane system 1:537 synthesis of 1:537 1,3-Dithianyl derivative 30:434 acylation of 30:434 Dithioacetal 30:439,458 transformation of 30:439 Diversity-oriented synthesis 29:452, 463 of aminocarbafuranoses 29:463 of carbafuranoses 29:452 Divinyl cyclopropane rearrangement 12:246,247 D-mannono-nitriles 10:463 catalytic hemihydrogenation of 10:463 Nef reaction of 10:464 D-manno-octulosonic acid (KDO) 30:434 stereoselective synthesis of 30:434 DMAP (4-dimethylaminopyridine) 11:154,157 DMAPP 7:98,110,11:201,202,19:520 DMAT synthase 11:202 DM-CCK sonication 18:844 DMDP (2,5-dihydroxymethyl-3,4dihydroxy-pyrrolidines 7:13,14 DMSO 6:310,329,330 DNA synthesis 30:61,67 DNA-scission 30:164 by alkylresorcinol 30:164 Doebher-von Miller quinoline synthesis 1:171 Double cyclization reaction 10:121,122 Double dioxygenation 9:560,561 Double indolization 1:8,9 Double Michael addition 8:414,415 with extended acceptors 8:414, 415 with substituted c~,13-unsaturated
esters 8:412-414 with 2-trimethylsiloxycyclohexadienes 8:417 with ~,13-unsaturated ketones 8:418 Double Michael reaction 3:143,144,735 DRH 30:448 synthesis of 30:448 Duhram 29:466 pyranoid carbasugars synthesis by 29:466 Ecdysone synthesis 25:242 Ecdysteroids 29:3 biosynthesis of 29:5 total synthesis of 29:17 Ecteinascidins 23:253,255 biogenesis of 23:253,255 ED-71 30:492 synthesis of 30:492 Edgar-Greene-Crabbe intermediate 14:365 Edman degradation 2:33;9:489,499,549, 551;19:797;25:437 EFE 30:835,838,840-842 by photoreaction 30:841 Ehrlich products 13:300 Ehrlich's reagent 9:592;19:755;26:1277 ( 10Z, 15Z)- 10,15-Eicosadienoic acid 26:90 total synthesis of 26:90 Eight-carbon sugars 4:172-175 by epoxide route 4:172-175 by osmylation 4:163-175 synthesis of 4:163-175 Eight-membered marine compounds 6:37 biosynthesis of 6:37 by cyclopropanone sliding reaction 6:37,210,218-220, 224-226,234 Eight-membered rings 3:77 by anionic oxy-Cope rearrangement 3:77 by [4+4] annulation 3:78 by dicarbonyl coupling 3:81 by Michael additions 3:83 by Nicholas reactions 3:83,84
914 by retroaldolization of enonene-photo adducts 3:74,75 by ring contractions 3:76,77 by transannular acylation 3:81, 82 from allylchromium-carbonyl coupling 3:81 synthesis of 3:73-111 Electrochemical oxidation 14:325 of azulenes 14:325 of guaiazulene 14:325,326 Electrocyclic rearrangement 6:72 Electroenzymic reactions 20:877 Electrolysis 19:35 Electromicrobial dehydrogenation 20:867 Electromicrobial reductions 20:877 Electron mediators 20:821-824 rt-Electron SCF-CI-DV MO method 17:39-40,45,47 Electron transfer 27:749 4,4'-bis-jatrorrhizine (v) 27:749 oxidative halogenation 27:750 oxygen transfer 27:751 N-dealkylation 27:754 O-dealkylation 27:754 Electron-demand 17:553 Electrophiles 19:464 1,4-Electrophilic addition 1:487,488 Eleven-carbon sugars 4:188 by osmylation 4:188 synthesis of 4:187-190 Elimination 16:366,416 thermal 4:44,45 enantioselective epoxidation 4:29,30,343-345 by molybdenum (VI) oxodiperoxo complexes 4:344, 345 by Sharpless procedure 4:29,30 of non-functionalised olefins 4:344,345 syn-Elimination 11:184,188 1,4-Elimination 11:187 y-Elimination 19:165 Elimination 6:540 13-Elimination 11:184;24:8,9,10,13,15, 23
antiperiplanar 12:17 of 3-mesyloxy-l-threonate 12:17 stereoselective 12:17 Htinnig base-mediated 14:291, 292 13-Elimination reaction 10:593 Elimination with KN(SiMe3)2 1:440 Elimination-addition mechanism 14:457 Eliminative cleavages 1:618,619 Elkin-Ahn-Houk model 30:437 for asymmetric induction 30:437 Ellagitannin oligomers 23:395-453 biogenesis of 23:395-453 Emmons-Horner-Wadsworth 29:471 carbaaldopyranoses synthesis 29:471 Emphibian skin 27:797 bombesin analog from 27:797 Enamide photocyclization 3:404-406 non-oxidative 3:404-406 reductive 3:407-410,414 Enamide-aldehyde cyclization 14:772-779 Enamidines 6:430,431 Enamine formation 1:452 Enamine related substrates 18:315-386 Enamine-aldehyde cyclization 14:785-787 (_+)-corynoline by 14:785-787 (+_)-11-epicorynoline by 14:785-787 (_+)-1 l-epiisocorynoline by 14:785-787 (+_)-isocorynoline by 14:785-787 Enamines 14:791-793 acid-catalyzed 14:791-793 cyclization 14:791-793 reactions with acetylenes 3:95,96 singlet oxygen cleavage of 8:261 13-Enamino imine substrate 18:343,366 13-Enaminoesters 14:738 cyclization of 14:738 dehydropyrrolizidines from 14:738 Enaminosulfoxides 6:317,318 in ~-ketoacid derivatives synthesis 6:317,318
915
Enantiofacial selection 13:70-73 asymmetric synthesis by 13:70-73 Enantiomeric chiral auxiliary 12:342 Enantioselective- 6:445,446 epoxidation 6:445,446 fermentative reduction 6:158 hydrolysis 13:54 Michael addition 6:86 oxidation 13:54 reduction 13:54 Enantioselective hydrolysis 12:337 with Candida cylindracea 12:337 with Pseudomonas sp. 12:337 Enantioselective reactions 16:559 Enantioselective reduction 18:288 Enantioselective synthesis 22:235; 24:185;29:244,490,492 of (-)-( 1R-SaS)- 1-hydroxyindolizidine 12:281 of (-)-slaframine 12:311,312 of (-)-y-rhodomycinone 14:14-17 of (+)-( 1S,SaS)- 1-hydroxyindolizidine 12:281 of (+)-stoechospermol 6:39,40 of 2,5-dialkylpyprrolidine ant alkaloids 6:443 of 7,20-diisocyanoadociane 6:86,87 of epi-lupinamine 14:741,742 of kaurane-type diterpenes 14:546 of lupinamine 14:741,742 of solenopsin B 6:429,430 of spirovetivane-type sesquiterpene 14:546 of (+)-albicanol 24:185 of carbaoxirose/carbaoxetoses 29:490,492 of Physarum polycephalum 29:244 Enantioselective yeast hydrolysis 12:338 Enantiospecific dehydrogenation 24:742 Enantiospecific reduction 24:742 Enantiospecific synthesis 4:625;12:313, 314,317,318
Enantiotopic discrimination 13:60-62 asymmetric synthesis by 13:60-62 Enders 29:389 steganes synthesis by 29:389 Enders reagent 4:327 Endiyne antibiotic 10:154 Endoperoxide rearrangement 4:419,420 Ene cyclization 1:294,159,17 Ene reaction 10:59 of 17(20) Z/E pregnenes 10:59 intramolecular 3:21 ;11:91,108; 16:17,246 of acryloyl chloride 16:246 of N-sulfoxyl imines 16:17 metallo-variant 3:21 of malondialdehyde 6:225,226 Ene-quinone-methide 5:744,747,749 Ene-type reactions 1:616,617 Engler synthesis 14:692-695 Enoate triol 12:15 enantioselective 12:15 from (-)-quinic acid 12:15 synthesis of 12:15 Enol ether 30:441 cleavage of 30:441 Enol ether reaction 4:437 with azetidinone 4:437 enterobacteriaceae 4:196 triheptoses in 4:196 Enol silyl C-glycoside 10:342 Enol silyl ether (enolate) 12:160,161, 163,164 3-Enol- 17,21-triacetate 9:416-418 Enol-acetate nucleosides 4:237 synthesis of 4:237 Enolacetylation 30:486 of trienone 30:486 Enolate alkylation 14:738 Enolate Claisen rearrangement 10:340 Enolate formation 10:410,41 l LDA-mediated 10:410,411 of u 10:410,411 A2,3Enone 12:25 Enone 8:176-178,181,183-186,191; 11:344 E-Enone 8:177 Z-Enone 8:177 Enone epoxidation 10:36
916
Enone-alkene photocycloadditions 6:33,34 Enones 10:352-354 Ent-calyculin A 26:1234,1235-1239, 1240 total synthesis of 26:1234, 1235-1239,1240 Enyne 8:277-281 Enyne carbocyclization 12:263 Enzymatic aldol condensation 10:535, 536;11:216 Enzymatic cleavage 21:167 Enzymatic coupling 2:392,394,396, 398,399,401 Enzymatic cyclization 7:100 Enzymatic degradation 27:191-196 of benzoxazinoid acetal glucosides 27:191 - 194 Enzymatic enantiotopic differentiation 13:624 Enzymatic hydrolysis 21:165 Enzymatic oxidation 21:499 of sulfides 14:517,518 sulfoxides from 14:517,518 Enzymatic reaction 16:108,110,111 Enzymatic reduction 12:338,58 Enzymatic synthesis 30:423 of oligonucleotides 13:279,280 Enzymatic transesterification 13:55 Enzymatically controlled 11:287 Enzyme 30:423,430,835,840 for synthesis of carbohydrates 30:423 Enzyme catalyzed conversion 2:372 Enzyme catalyzed reactions 7:29 Enzyme intermediates 27:740 reactivity of 27:740 Enzyme-aided enantioselective acylation 18:428 Enzyme-aided enantioselective hydrolysis 18:426-428 Enzyme-carbohydrate interactions 7:29-86 Enzyme-catalyzed acylation 12:346 Enzyme-catalyzed reactions 9:612,176 Enzymic galactosylation 10:469 Enzymic generation 27:77 of trihydroxy fatty acids 27:77
24-Epi-catasterone 25:425
by Bayer-Villager oxidation 25:425 Epiisopodophyllotoxin 24:762,766,771 synthesis of 24:762,766 C-6Epimer synthesis 29:439,442 in alkaloid 223A 29:439,442 Epimerization 6:558,559,367 Epoxidation 11:470;16:571 ;24:30-32, 62,63,65,66,68,72,73,87,110-112, 175,188-190;27:753 enantioselective 16:571 hydroxy-directed 19:259 of allylic alcohol 16:342 of cannabidiol 19:236 of enol 19:259 ofenolsilyl ether 16:332 of ketone 8:182 of limonene 16:229 of methyl perillate 6:545 of stigmasterol 16:334 of vinylsilane moiety 16:268 of ~,13-unsaturated ketones 16:571 of ~-patchoulene 16:151 of styrene 27:753 regioselective 1:436,439 Sharpless 12:236 Sharpless asymmetric 1:278,279, 507,508,510 stereoselective 8:179-182; 16:349;19:372 with alkaline hydrogen peroxide 16:349 with t-BuOOH-KH 8:180-182 with t-BuOOH-Ti (OPr-i)4' 3:100,101 with Vo(acac)2/t-BuOOH 1:436,439 ~-Epoxidation 11:383 C (2,3)-13-Epoxidation 10:39,40 of allylic alcohols 10:39,40 Sharpless 10:39,40 with VO (acac)2-TBHP 10:39, 40 Epoxide alkylation 14:746 Epoxide opening 1:439 acid catalysed 1:439
917
cuprate mediated 1:536 organo cuprate mediated 1:536 with cuprate 1:456,457 with dimethyl cuprate 1:523 with Redal 1:538 Epoxide rearrangement 6:136,550,551 ~-Epoxide reduction 4:418 Epoxide-furanoid rearrangement 6:162 Epoxidisation system 7:105 Epoxy allylic ether 10:590,591 cyclization of 10:590,591 from D-ribose 10:590 synthesis of 10:589,590 ~,[3-Epoxy-aldehyde 30:473 synthesis of 30:473 Epoxyaldehydes 27:82 generation of 27:82 hydrolysis products of 27:82 Ergosterol 30:489,506,508 ozonolysis of 30:489 Ergosterol biosynthesis 30:485 Erythropoietin (EPO) 29:547,548 oxidation of 29:547 periodate oxidation of 29:548 Eschenmoser reaction 8:211 Eschenmoser ring contraction 9:601,602 Eschenmoser-Claisen rearrangement 10:417,419-421,427,428 Eschweiler-Clarke methylation 10:84, 165 Eschweiler-Clarke reaction 1:203, 384,385 Ester enolate Claisen rearrangement. 3:236,246,259,261-265,267-270, 274-276,278-280; 14:497 Ester epimerization 1:466 Ester exchange reaction 4:519 Ester type glycoside linkage 7:154,155 Esterase 13:303 Esterification 4:91,92,276,292,391,409, 412,413 Etherification 4:718-720 ~-Ethoxyacrylonitrile 30:449 photolysis of 30:449 Ethoxyvinyllithium 30:458 as reagents 30:458
l-Ethoxyvinyllithium 30:458 reaction with 30:458 ozonolysis of 30:458 Ethyl 2-(bromomethyl)acrylate 30:451 nucleophilic addition of 30:451 Ethyl 2-diazoacetate 30:446 reaction with 30:446 Ethyl or acrylate 30:450 radical conditions 30:450 reaction with 30:450 (2S,3S)-2-Ethyl-3,4-isopropylidenedioxy-propan- 1-ol 30:39 from L-malic acid 30:39 role in (-)-pironetin synthesis 30:39 Ethylene biosynthesis 25:657 7-O-Ethylrosmanol (abietane diterpene) 29:575 synthesis from carnosolic acid 29:575 Eu (fod)3-mediated [4+2] cycloaddition 4:121,122,143 Diels-Alder reaction 4:121,122 Eu (hfc)3 4:326 Eu FODTM 1:420,421 cyclocondensation using 1:420, 421 6 -Eudesmanolides 24:72,73 Eudesmin 24:755 synthesis of 24:755 Evan's alkylation 19:62 Evan's reduction 18:253 Evans aldol methodology 16:483 Evans aldol-condensation reaction 30:13,33 Evans asymmetric alkylation 1:455,456, 469,604 Evans asymmetric induction procedure 14:534 Evan's asymmetric strategy 12:435,436 Evan's chiral auxiliaries 12:435-438 Evans oxazolidinone-mediated syn-aldol condensations 30:44 Evan's rearrangement 16:296 Evan's-Cope reaction 12:193 Evan's-Cope ring expansion 12:192 Exo addition 8:160,161
918 Exo orientation 14:753 Exo-enol tautomer 14:101
rt-Facial selection 12:419-422 in methoxybromination 12:419-422 in methoxyselenylation 12:421, 422 reversed 12:419-422 Facial selectivity 10:36 FAMSO 6:311-313 aldehyde synthesis by 6:311-313 alkylation of 6:313 allylation of 6:315,316 dianion of 6:323-325 methyl methylthiomethyl sulfoxide in 6:309-325 organic synthesis by 6:311-323 oxidation of 6:311 preparation of 6:309-311 Farnesylation 24:409-410 of protein 24:409-410 Fast oligonucleotide deprotection (FOD) 13:266 Fat 27:402 hydrolysis of 27:402 Favorskii reaction 6:335 Favorskii rearrangement 8:225;10:410; 16:242;20:69,70 anti-Felkin product 30:17 Felkin-AHN model 11:234,440,474, 643;12:21;19:474 Felkin-ANH conformation 3:255,134 Felkin-ANH transition state 1:402,406, 423 Felkin-Nguyen (Anh) 8:213 Fenton process 25:931 Fenton reaction 22:316,327;25:330,634, 644 Ferredoxin-NAD oxidoreductase 20:835 Ferrier reaction 10:347,419,433-437, 510 Ferrier rearrangement 13:191,200,201, 203,210 Ferrier-type reactions 3:212,213 elimination-addition by 3:212, 213
filifolone by 3:40 synthesis of 3:40 Ferrihemoglobin 26:985,986,991 -mediated oxidation 26:991 Ferrous sulphate reduction 4:422,432 Fetizon oxidation 4:340,343,370 Fetizon's intermediate 12:196,198 Fetizon's photochemical route 12:195 Fetizon's reagent 1:349,366,508,570; 18:28 Fischer carbene complexes 1:505,506 Fischer indole reaction 14:845 Fischer indole synthesis 1:79,144,152, 284;11:285,492 Fischer indolization 1:15,51,60 Fischer projection 11:422,423 Fischer-Helferich procedure 4:222 Fischer-Kiliani synthesis 4:157-159, 175,179 Fisher-Irwin test 9:386 Fitzsimmon cycloaddition 11:447 Flagpole type interaction 14:736 Flash pyrolysis 1:250 Flash vacuum pyrolysis 3:27,588 Flash vacuum thermolysis 1:337 Flavone glycosides 30:235 acidic hydrolysis of 30:235 Flavonoidal alkaloids 21:130 synthesis of 21:130 Fluorination 13:81-83 of alkylmalonate 13:83 of chiral half-esters 13:81 of monalkyl malonic acid 13:81 with 1-fluoro-2,4,6-trimethylpyridinum-trifluoromethane sulfonate 13:82 5-Fluoro-6-fluoro-substituted alkaloids 29:344 as synthetic fluorinated compounds 29:344 5-Fluoro-Nb-acetyltryptamine 29:344 as synthetic fluorinated compounds 29:344 25-Fluoroponasterone A 29:19 as synthetic ecdysteroid analogues 29:19 Fluorotryptamines 29:344 as synthetic fluorinated compounds 29:344
919 6-Fluoro-13-hydroxy-Nb-acetyltryptamine 29:344 synthetic fluorinated compounds 29:344 5-F1uoro- 13-h y dro xy-Nb-acety 1tryptamine 29:344 as synthetic fluorinated compounds 29:344 FOD (last oligonucleotide deprotection) 13:361,267,268 Formation 27:346,877 of (+)-abscisic acid 27:346 of (-)-abscisic acid 27:346 of (HOABA) 27:346 ofphaseic acid 27:346 Formylation-diazotransfer procedure 10:594,595 8-Formyloct-5-enoate 26:86 wittig reaction of 26:65,66,70, 72,73,75,81,83-91 Four component condensation 12:11, 115,117 Four-carbon polar annulation 6:17,21, 29,30 Fourier transform methods 5:3 FPP 7:110,122 Fragmentation 25:255 of manoyl oxide 25:245, 248-250,253-255 Fragmentation-recombination 10:412 of ~,13-unsaturated methoxymethyl ester 10:412 to c~-hydroxymethyl unsaturated ester 10:412 Fraser-Reid synthesis 12:13,14 Free radical condensation 10:355 Free radical cyclization 3:326 Free radical deoxygenation 6:21 French research groups 29:498 homochiral (+)/(-)-calystegines B2 synthesis by 29:498 Friedal-Crafts acylation 8:16,13:448, 18:234 Friedal-Crafts reaction 1:499-501; 5:485;10:312,313;11:140,318,319; 14:7,670-676,681-684;19:306; 20:692
intramolecular 10:312,313, 11:140 Friedel-Crafts alkylation 6:61,62,74, 75;10:376;18:23 l Friedel-Crafts annulation 18:70 Friedel-Crafts products 6:309 Friedlander reaction 3:386 Fritsch-Buttenberg-Wiechell rearrangement 18:171 from anacardic acid 9:341 Frontal cortex 30:377 serotonin synthesis in 30:377 Fuchs synthesis 18:892-895 Fukiic acid (phenolic acid) 29:582 synthesis from fukinolic acid 29:582 Furan-based Diels-Alder approach 29:470 carbaaldopyranoses synthesis by 29:470 Furst-Plattner effect 19:357 Furuta 29:466 pyranoid carbasugars synthesis by 29:466 cis-Fused bicyclic furanone 29:452 carbafuranose synthesis from 29:452 Fused eight-membered ring systems 6:468-474 Fused eleven-membered ring system 6:494-497 Fused lactone nucleoside synthesis 4:252 Fused nine-membered ring system 6:472-482,483-493 Fusion reactions 4:236,38 Fusion technique 4:222 Galactose prodrugs 21:161 synthesis of 21:161 Or 14:150 of methyl 2-O-benzyl-4,6-Obenzylidene-13-D-galactopyranosides 14:150 [3-Galactosylation 10:470 Gassman oxindole synthesis 3:320
920
G-coupled proteins 30:808 phosphorylation of 30:808 GDIBOA 27:188,209 synthesis of 27:210 GDIM2BOA 27:188,209 synthesis of 27:210 Geiwiz and Hasslinger 29:185 pisiferic acid synthesis by 29:185 Generation 27:64,69-71,73,74,75,78, 79,83 of 13-oxo-9,11-octadecadienoic acid 27:73 of 13-oxo-9-hydroxy- 10octadecenoic acid 27:73 of 9S-hydroperoxy 10E, 12Z, 16Zoctadecatrienoic acid from 27:70,71 of jasmonic acid 27:64,71-73 of 16S-hydroperoxy9Z, 12Z, 14E-octa-decatrienoic acid (16S-HPOTE) 27:70 of 13-hydroperoxy-9Z- 11Eoctadecaenoic acid 27:69-71 of 2E-4-hydroperoxy-2-nonenal (4-HNE) 27:74,75,83 of 16-hydroperoxy- 10,12,14octa-decatrienoic acid 27:71 of LO" radicals 27:78,79 of traumatic acid 27:75 of epoxyaldehydes 27:82 of salicylic acid 27:63 8-Geranylapigenin 28:234 synthesis of 28:234 Ghosez cyclization 26:1230,1231 Gilben's reagent 26:1245 Gilman reagent 22:206 Gingerol 23:848 biosynthesis of 23:848 Glucocorticoid degradation 21:657 Glucose 27:394 propranol from 27:394 Glucuronic prodrugs 21:169 synthesis of 21:169 Glycals 30:453-458 homologation of 30:455 synthesis from 30:453-458 Glyco analogues activity 30:817 in vivo 30:817
Glycosidase inhibitors 29:467 carbaaldopyranoses synthesis of 29:467 Glycosidation 6:276,277 by mycosamine 6:276,277 by silicon ether 6:262,276,277 in (-)-pseudopterosin-A synthesis 6:74,75 Noyori's 1:671,672 of 1-O-acetyl-oxetanose 10:603 of adenine 10:605 of amphoteronolide B 6:276,277 regioselective 6:262 stereochemistry of 3:197 with oxetanosyl chloride 10:605 with silver triflate/TMU 1:670, 671 I3-directing 2-bromosugars 3:202 N-Glycosidation 10:595-607 oxetanocin-A synthesis by 10:595-607 with l-O-acyl-oxetanose 10:597-604 with oxetanosyl derivative 10:595-607 with oxetanosyl l',alide 10:604-607 Glycosyl thioformimidates 10:357 from glv osyl nitriles 10:357 C-Glycosylatio,, 1:429,430,513,514 c~-Glycosylation 13:217 1,2-cis-Glycosylation 14:209 1,2-trans-Glycosylation 14:209 c~-Glycosylation 30:457 O-Glycosylation 30:814 role in 8 receptor affinity 30:814 role in g receptor affinity 30:814 Glycosylation 6:395,397,398,400; 10:470,471,472,474-486 cis-Glycosylation procedures 14:202 Glycosylation reactions 14:201-259 Gmelanone 24:785,786 biomimetic synthesis of 24:785,786 Gomberg-Batchman-Hey reaction 20:310 Gorgiacerone 23:173 synthesis of 23:173
921
Grignard addition 10:147,167,180; 16:380;19:39,45,62,541 Grignard coupling 19:45 Grignard cross coupling reaction 14:575 Grignard reaction 1:261,262,533;4:330332,353,354;6:159,549,550;8:165, 166;9:344,345,352,527 ;11:81,82, 248,249;14:670;18:473,630;20:571, 589,592,595,599,600,604 Grignard reagent 4:160;19:33,35-36,38, 513,518 ;20:569,585,596,598 ;21:384; 30:30 Group transfer polymerization 8:409 Grubb synthesis 6:46,47 Grubbs ruthenium catalyst 30:463 Guaiacylglycerol-13-O-coniferyl alcohol 27:760 polymerization of 27:760 Gurjar's syntheses 30:33-37 of (-)-pironetin 30:33-37 Gypsogenic acid 24:151-153 mimonosides Ma from 24:151, 152 mimonosides Mb from 24:151, 152 mimonosides Mc from 24:151, 152 Haber-Weiss reaction 22:327,435; 26:975 Hakomori's procedure 27:512 Halipanicine 28:661 total synthesis of 28:661 Halogenation 27:749,752 of olefins 27:749,752 Hanessian reaction 1:511,512 Hanessian's deconj ugation-epimerization 12:13 of avermectin Bja derivatives 12:13 Hanessian's epimerization 12:28 macrocyclization with 12:28 Hanessian's procedure 12:347 from debenzylidenation 12:347 Hanessian's synthesis 12:12-15 of avermeetin B~a 12:12-15 Hantzsch synthesis 4:86 racemization during 4:86
Haslinger and Michel synthesis 14:689-692 of taxodione 14:689-692 Head-to-tail polymerization 27:774 Heathcock's asymmetric aldol reaction 18:283 Heck arylation 19:274,19:277 Heck coupling 19:276 Heck reaction 16:367,391,400,412,416, 418,427,429,430,432,435,438,439, 447;18:96;19:22,78,279,284 asymmetric 19:22 intramolecular 16:429,430, 438,439 of olefin 19:279 palladium-catalyzed 19:78 Pd(0) catalyzed 16:439 silver modifaction of 16:429 with 1-octen-3-one 16:391 Heck reaction conditions 19:227,279 Heck vinylation 16:432 intramolecular 16:432 Hemiacetal ethers 27:189 retrosynthetic analysis of 27:189 Hemiacetal moiety 30:450 reduction of 30:450 ozonolysis process 30:450 Hemiacetalization reaction 30:437 Henry condensation 1:408,409 Henry reaction 19:120,165,173 pyperidine-catalyzed 19:165 Heptanone 30:41 oxidation of 30:41 Heptulosonic 30:473 synthesis of 30:473 Heptulosonic acid analogues 30:473 Mukaiyama reaction of 30:473 Hetero Diels-Alder reaction 16:654 addition of 16:654 approaches to 16:456 asymmetric 11:260-267 diastereoselective 12:424,425 enantioselective 11:260-267 for nepetalactone synthesis 4:604,605 for tylophorine synthesis 4:604,605 gephyrotoxin 223AB by 4:606 gephyrotoxin by 4:606
922
iminodienophile in 4:604,605 intramolecular 6:449;14:757, 758;19:43,223 intramolecular Lewis acid catalysed 1:553 lysergic acid by 4:604,605 monomorine I by 4:606 of 2-methoxybutadiene 12:257 oxazoles in 4:604 pyran adduct from 12:257 reaction of 16:439 tetrazines in 4:604 triazines in 4:604 using nitroso dienophiles 1:378 with ethyl glyoxalate 12:257; 13:69,177,187,490,625,757,758 I3-amino acid by 12:158 Hetero Diels-Alder type cycloaddition 24:235 Hetero-Cope rearrangement 8:205 Heterocycloaddition 1:359-392 Heterodienophiles 4:143 in D-allo-threonimal 4:143 in Diels-Alder reaction 4:563 Heterolytic dissociation 6:307,308 Heterolytic fragmentation 13:575 Heteromercuration 1:382 of carbamates 1:382 (5Z,9Z)-5,9-Hexacosadienoic 26:82 total synthesis of 26:82 (Z)-9-Hexadecenoic acid 26:70 methanolysis of 26:65 Hg(H) mediated Ritter reaction 11:281, 282 (+)-313-Hidroxinagilactone F 28:503 synthesis of 28:503 High pressure technique 4:121 [4+2] cycloaddition by 4:121 in Diels-Alder reaction 4:112 Hilbert-Johnson reaction 1:399,400; 4:223,224,230,239 HOABA 27:346 formation of 27:346 Hoffmann degradation 18:51 Hoffmann rearrangement 1:410,411 Hoffmann's cycloaddition 18:257 Hoffmann-LaRoche 28:71 vitamin A synthesis by 28:71 Hoffmann-like rearrangement 19:14
Hoffmann-Loeffier photocyclization 6:437 of N-chloroamines 6:437 Hofmann degradation 6:480,489;9:547, 548;14:771-773,793-795 Hofmann elimination 6:481,488;16:53 Hofmann reaction 14:868 Hofmann rearrangement 3:313 Holton's taxol synthesis 12:220 Homoaldol reaction 8:156,157 Homoallylic alcohol 11:346,347 from epoxide 11:346,347 with vinylmagnesium bromide 11:346,347 Homoallylic coupling 10:118 Homochiral (+) synthesis 29:498 by Boyer and Lallemand 29:499 by French research groups 29:498 Homochiral diol auxiliaries 1:579-582 Homochiral ketone auxiliaries 1:579, 583,584 Homoenolate ions 3:217 from allylic esters 3:217 Homologation 6:32;11:257,258, 462-464;12:82;14:175 Homooligomers 27:768 of trans-resveratrol 27:768 Hoppe coupling 10:15 Hornet Bestmann oxidation 8:207 Homer reaction 6:285,286 Horner-Emmons carbon elongations 29:127 in sesquiterpenoids drimane-type synthesis 29:127 Horner-Emmons condensation 1:410, 411;10:13-17,19;11:432;14:129; 16:655;18:288 Horner-Emmons coupling 14:115,123 Horner-Emmons olefination 10:534, 441,442;14:126;16:460,490;18:288, 633 Horner-Emmons olefination procedure 30:458 for ketene dithioacetals 30:458 Horner-Emmons reaction 1:448,450; 5:828;8:16,209,270,271 ;9:356;10:43; 13:175,210,570;14:593 ;18:481,586;
923 19:14,45,62;20:567,575,580,585, 588,591,595,596,599,606;30: 32 Horner-Wadsworth-Emmons condensation 19:529 Horner-Wadsworth-Emmons olefination 20:567;21:432 Horner-Wadsworth-Emmons reaction 12:30;20:72-74 ;30:34,46 Horner-Wittig olefination 9:525,6:545, 546;10:157,159,164 ;16:673 ;19:448; 20:702 Horner-Wittig-type reagent 19:452 Houk's "inside crowded" model 12:57 Houk's "outside crowded" model 12:58 Houk's concept 11:240 House procedure 10:308,309 House's conditions 12:46,47 Hoye's 1:672 of (+)-3,3-dibromocamphor 16:135 of levoglucosenone 14:269 with NBS 19:314 Hoye's bromination 1:678 Hoye's procedure 6:56,57 Huang-Minlon modification 14:684 Huang-Minlon reduction 14:674,676, 677 Hudson lactone rule 10:262 Huisgen pyrrole synthesis 13:445 Huperzine A 21:746-748 synthesis of 21:746-748 Huperzine A 21:748,764 synthesis of 21:746-748 Hydration 4:332 mercury catalysed 4:332 of acetylenes 4:332 Hydrazine 1:20 reduction with 1:20 1,4-Hydride reduction 12:154 Hydride reduction 14:153;19:372 of sulfonates 14:153 [ 1,2J-Hydride shift 10:216,222;19:518 Hydride shift 9:45,46 2,6-Hydride shifts 4:626,627,634,643 in camphor derivative 4:634,643 in rearrangement of camphor 4:626,627 Hydride transfer 17:486-487 6,2-Hydride-shift 4:650,651
Hydroalanation 10:21,24,29 Hydroboration 8:470-473,475,478; 10:15;11:83,84,316,317,319;14:456, 681,682;16:472;19:367 highly stereoselective 12:151,152 of allylic ethers 4:116 of olefin 12:151,152 of vinylic ethers 4:116 regioselectivity 4:116 stereoselective 19:367 to alcohol 12:151,152 Hydroboration-oxidation 14:773,774; 24:203,204,210 Hydrocarbons 27:700 from olive oil 27:700 Hydroformylation 16:409 Hydrogen abstraction 16:41 Hydrogen peroxide oxidation 14:324, 325 Hydrogen phosphonate method 4:274-276 of oligonucleotide synthesis 4:274-276 mechanism of 4:275 1,5-Hydrogen shift 1:327 Hydrogenation 24:36,37,100,101,104,
119,182;30:486 2,3-anti selective 12:35,36
heterogenous 12:36 homogenous 12:35,36 of double bond 19:45;19:307 of ketones 19:27 of methyl acetoacetate 13:72,73 of phenyl sulfone derivative 30:486 of pyranone 19:468 of 13-ketoester 19:29 on naphthalene-Cr (CO)3 complex 4:343,344 stereoselective 12:151,152; 19:296,301 using Adam's catalyst 19:70 1-Hydrogenation 26:66 of 10,13-dimethyl-9-tetradecenol 26:66 Hydrogenolysis 6:276,426,435,451,168, 169;19:6,36,38,42,104,332,362, 367-368,37;121:200;30:17
924
of PMB group 30:17 Hydrolysis 1:678,679,682 asymmetric 1:678,679,682 by Candida cylindracea lipase 1:685 by lipases 1:684,685 by pig liver esterase 1:685 by pig pancreatic lipase 1:685 by Pseudomonas fluorescens lipase 1:685 of N-acetyl ~z-amino acids 1:678,679,684,685 acid-catalyzed 11:361 enantioselective 13:54 of abscisic acid-GE 27:354 of fat 27:402 of phosphate 27:872 photochemical 6:331,333 selective 6:285,286 Hydrolysis products 27:82 of epoxyaldehydes 27:82 Hydrolytic cleavage 12:428-430 Hydrolytic fragmentation 12:198 Hydroperoxide initiated 22:346 chemiluminescence 22:346 16-Hydroperoxy- 10,12,14-octadecatrienoic acid 27:71 generation of 27:71 9-Hydroperoxy- 10,12,15-octadecatrienoic acid 27:74 by Baeyer-Villiger reaction 27:94 transformation of 27:74 2E-4-Hydroperoxy-2-nonenal (4-HNE) 27:74,75,83 generation of 27:75 13-Hydroperoxy-9Z- 11E-octadecaenoic acid 27:69-71 generation of 27:69,70 or acids 1:446,447 as chiral building blocks 1:680,681 3-Hydroxy acids 4:625 as chiral synthons 4:625 w-Hydroxy acids 8:176,233,234,236 cyclization of 8:234 intramolecular esterification of 8:176 lactonization of 8:233,234,236
Hydroxy amino acids 12:431-438 synthesis of 12:431-438 co-Hydroxy C~4 30:145 synthesis of 30:145 (R)-2-Hydroxy carboxylates 20:840-842 dehydrogenation of 20:840-842 to 2-oxo-carboxylates 20:840-842,853 preparation of 20:842 N-Hydroxy compounds 8:376 Hydroxy dithioketal 10:203,204 trans-Hydroxy epoxide 10:205,206 cyclization of 10:205,206 Hydroxy epoxides 10:205-207 cis-Hydroxy epoxides 10:207 [3-Hydroxy ester 1:689-701 as chiral building blocks 1:689-701 from (~-bromoalkyl) boronic ester 11:425 synthesis of 11:425 Hydroxy ketones 10:205 syn selectivity of 10:205 3[3-Hydroxy- 13,14,15,16-tetranorlabda7,9( 11)-dien-( 19,613),(12,17)-diolide 28:508 synthesis of 28:508 12-Hydroxy-2-methyldodecanal 26:70 wittig reaction of 26:70 2-Hydroxy-3-(2-methoxyphenyl) propenoic acids 30:222 cyclisation of 30:222 3-Hydroxy-4-pentenyl amines 14:568 stereoselective cyclization of 14:568 to pyrrolidines 14:568 8'-Hydroxyabscisic acid 27:350 isomerization rates of 27:350 (3R)-3-Hydroxybutanethioate 13:500 boron enolate of 13:500 (R)-3-Hydroxybutanoic acid acetals 1:610 diasteroselective allylation of 1:610 3-Hydroxybutyrates 4:439 anti-products formation 4:439 in thienamycin synthesis 4:431
925 ~-lactam formation 4:446 lithio dianions of 4:441 3-Hydroxybutyric acid 4:431,438,440, 465,471,479,480 acid chlorides of 4:471 in thienamicin synthesis of 4:438-440 R,S-4-Hydroxycyclopentenones 6:315 absolute configuration 6:315 asymmetric synthesis 6:315 from D,L-tataric acid 6:315 10-Hydroxydecanoic acid 26:65 methanolysis of 26:65 Hydroxy-directed epoxidation 12:300 of trifluoracetate salt 12:300 2-Hydroxyfuran-2-one 30:222,224 decarboxylation of 30:222 lactonisation of 30:222 13-Hydroxyketone 30:23 1,3-anti reduction of 30:23 Hydroxyl inversion 1:204,205 Hydroxyl removal 1:454,456 cis-Hydroxylation 1:413,415 stereoselective 1:413,415;4:511 stereospecific 4:503,504 Whiteside's procedure 1:668 with Ba(CLO3)2 1:260 with CuC12/Cu/O2 5:827 with osmium tetroxide 4:508,509 with OSO4 1:260 12l]-Hydroxylation 13:663 Hydroxylation 5:827;24:70-72,76,178, 179;27:346,749,754 by cytochrome P450 27:346 by stereospecific double bond 11:464 of (l'R)-(-)-Abscisic acid 27:348 of arenes 27:749 of indoles 27:754 c~-Hydroxylation 4:331,333;13:43 cis-Hydroxylation 4:45,145,204,205, 344 lincosamine derivative from 4:145 of acrylates 4:45 of E-allylic alcohol 4:204 of Z-allylic alcohol 4:205 with OsO4-chiral base 4:344
C-3 Hydroxylation 7:359-361 1113-Hydroxylation 9:417 o-Hydroxylation 5:826 of 2-alkylbenzoic acids 5:826 ~-Hydroxylation 27:199 of cyclic hydroxamic acid
27:199
Hydroxylation 28:335 of MFA 28:335 of paraherquamide A 28:331,367 trans-Hydroxylation 1:413,414 of olefin 1:413,414 of olefinic double bond 16:16 with H202 1:260 with WO3 1:260 14~-Hydroxymarcfortine A 28:338 synthesis of 28:338 15~-Hydroxymarcfortine A 28:338 synthesis of 28:338 16c~-Hydroxymarcfortine A 28:338 synthesis of 28:338 4-Hydroxyphenylpyruvic acid 30:221 dimerisation of 30:221 8-Hydroxyquinaldic acid 26:991 microbial transformation of 26:991 Hyperforin 30:611,627,628 alkylation of 30:627 by acylation 30:627 cleavage of 30:611 oxidation of 30:627 Ichikawa 29:492 carbaoxirose/carbaoxetoses synthesis by 29:492 Ikegami 29:485 valiolamine synthesis by 29:485 Imine 12:173 [2+2] cycloaddition of 12:173 azaallyl anions from 1:331-344 cis reduction of 6:428 deprotonation of 1:331-344 preparation by Standinger reaction 1:352-353 trans reduction of 6:428 trans-3-acetyl-[5-1actam from 12:173
926
with diketene 12:173 ylides from 1:331-334 Iminium 'A' 2:390,2:398,402 Iminium 'B' 2:390,390 Iminium cyclization 1:243 Iminium ion cyclization 1:286,287 to vinylsilanes 1:286,287 Iminium ion-vinylsilane 19:52 Iminium ion-vinylsilane cyclization 12:454 [3-Imino carboxylic acid 8:384 2-Imino cyclic ethers 10:215 synthesis of 10:215 Imino Diels-Alder approach 14:732,733 Imino Diels-Alder reaction 4:36,37,604 [3-Imino sulfoxide substrate 18:382 5,8-Imi n o- 7-O-me syl-2,3,5,8-tetradeoxy-D-glucooctano- 1,4-1actone 12:325 Iminodienophile 4:604 in Diels-Alder reaction 4:604 Indole N-tert-butyloxycarbonyl 3:309, 310 thermolytic deprotection 3:309, 310 Indoles 27:754 hydroxylation of 27:749,754 Indoles synthesis 1:79,144,152 Fischer 1:79,144,152 Smith 1:360,365 Indolizidine alkaloids 7:11-13,453-502 synthesis of 1:360-365;10:556, 561;16:453-502 Indolizidone 12:298 cross-aldolisation of 12:298 from L-proline thioester 12:297 3-Indolyl-acetonitrile 11:281,282 Ritter reaction of 11:281,282 with (-)-~-pinene 11:281,282 Indolylmagnesium iodide 1:7 Indomethacin 27:689,690 INEPT (Intensive Nucleus Enhancement by Polarization Transfer) 27:469 influence on intracutaneous permeability 27:378,380 Inhoffen-Lythgoe diol 1:591,592 synthesis of 1:592 INOC reaction 1:480,481
Inouye's photochemical route 12:198 Interconversion 27:336 of abscisic acid ring 27:336,338 Intermolecular additions 24:201 Intermolecular aldol condensation 10:318-320 Intermolecular cationic [5+2] cycloaddition 8:160,161 Intermolecular cyclization 6:59 spirosystems construction by 6:59 Intermolecular Diels-Alder cycloadditions 24:33 Intermolecular Diels-Alder reaction 6:549,550;24:768 Intermolecular Knoevenagel type cyclization 24:33-40 Intermolecular Michael reaction 14:552 enantioselective 14:552 Intermolecular O-alkylation 8:198,199 Internal aldolization 6:81 in (+)-2-isocyanopupukeanane synthesis 6:81 Internal alkylation 6:74 in (+)-9-isocyanopupukeanane synthesis 6:80 Internal Diels-Alder reaction 6:86,87 Intramolecular [2+1] cycloaddition 6:52 Intramolecular [2+2] cycloaddition 12:193 Intramolecular [2+2] photoaddition 12:210 Intramolecular [2+2] photocycloaddition 6:69 Intramolecular [4+ 1] pyrroline annulation 1:250 Intramolecular [4+2] cycloaddition 6:85 in (_+)-sinularene synthesis 6:85 in 7,20-diisocyanoadociane synthesis 6:86,87 olefin tropolone 5:799 Intramolecular 1,3-dipolar cycloaddition 12:318 Intramolecular acetalization 14:60 Intramolecular acylinitroso Diels-Alder reaction 1:386 Intramolecular addition 10:3-11 to chiral sulfoximines 10:3-11
927
to chiral vinyl sulfoxides 10:3-11 Intramolecular Alder erie reaction 10:222,224 Intramolecular aldol condensation 6:549,550,231;15:235,269,297; 24:779,780 Intramolecular aldol cyclization 6:36, 66,67;18:633 in poitediol synthesis 6:36 in (-)-upial synthesis 6:66,77 Intramolecular aldol reaction 24:15,24, 25 Intramolecular alkylation 6:42,43; 8:225-233,540,558;24:13 Intramolecular amidoalkylation 1:246 Intramolecular aminomercuration 10:532,540;12:333 Intramolecular arylation 12:447-452 Intramolecular base-induced rearrangement 14:374 Intramolecular C-alkyation 24:9-11 Intramolecular carbenoid displacement 1:259 Intramolecular carbocyclization 24:15 Intramolecular chelation 14:53 Intramolecular Claisen condensation 18:299 Intramolecular coupling 6:546,547 Intramolecular cyclization 2:282; 21:36,37,398 nickel-catalyzed 2:282 spirosystems construction by 6:59 in (_+)-9-isocyanopupukeanane synthesis 6:82,83 Intramolecular cycloalkylation 6:6; 24:9,10 in (+)-amjitrienol synthesis 6:53 in tricyclic natural products synthesis 6:74 Intramolecular cyclopropanation 6:73, 74 Intramolecular Diels-Alder reaction 4:601,602 betaenone B by 4:601,602 coronafacic acid by 4:596,597 diplodiatoxin by 4:600-602 endo rule 4:18
fused versus bridged product 4:565 in biosynthesis 4:616,621 kinetic selectivity 4:601 solanapyrone A by 4:598 stereoselectivity 4:595,596 Intramolecular displacement reaction 12:311,344 Intramolecular diyl trapping reaction 6:46 Intramolecular double Michael addition 8:418 Intramolecular ene reaction 24:29,30, 759,760 Intramolecular glycosylation 14:236 Intramolecular heteroene reaction 12:295 Intramolecular Horner-Emmons condensation 12:341 Intramolecular Horner-Emmons reaction 24:15 Intramolecular Michael addition 6:70, 71 in (_+)-sanadaol (I]-crenutal) synthesis 6:70,71 Intramolecular Michael cyclization 14:552 of an acyclic compound 14:552 Intramolecular Michael reaction 6:178, 184,196 asymmetric 14:551-567 by chiral enamine 14:551-567 enantioselective 14:551-567 Intramolecular oxidative coupling 6:480 Intramolecular photocycloaddition 6:34, 35,54 in (+_)-epi-precapnelladiene synthesis 6:34,35 in isoamijiol synthesis 6:54 Intramolecular Pinner reaction 15:415 Intramolecular Prins reaction 24:64,65 Intramolecular radical-induced carbocyclization 24:15-18 Intramolecular reaction 11:45-47 (2+2) cycloaddition 11:45-47 [4+4] cycloaddition 11:17 1,3-dipolar cycloaddition 11:283-285 aldehyde-ketophosphonate
928
condensation 6:264,265 aldol condensation 11:90,108, 113,115;12:82 alkylation of 8:176,177 amidoalkylation 10:108 amidomercuration 12:281 aminolysis 12:279 annulation 10:407 asymmetric hydrosilylation 13:72 azido-olefin cyclization 13:447, 448 Biellmann coupling 10:6-10 C-C bond formation 12:65 cross coupling reaction 10:163 cross-aldolisation 12:289 cyclization 10:631-633;12:281, 327 dicarbonyl coupling 11:345, 364-367 Diels-Alder reaction 10:51,52, 155,409;11:11,92,93,99,108; 13:108-115;14:745 double cyclization 10:83 displacement 12:347 ene reaction 11:91-108 epoxide alkylation 14:746 esterification of 8:176 etherification 12:65 Friedal-Crafts acylation 10:131 Friedal-Crafts reaction 10:312, 313 hetero Diels-Alder reaction 6:449 Horner-Emmons condensation 10:13-17 imino Diels-Alder approach 14:732,733 Michael addition 11:312;14:736 Michael reaction 9:435,437; 10:51,52;13:180-443 mixed Claisen condensation 12:104 Mukaiyama condensation 10:181,182 N-acyliminium ion cyclization 11:284,285 nitrile oxide cyclization 14:745 nitrone cycloaddition 14:744
O-C bond formation 12:83 P~-allyl Pd alkylation 10:10-13 photocycloaddition 11:20 photoreduction 12:283 proton transfer 12:102 Pummerer reaction 10:682 rhodium II mediated 10:407 ring contraction 11:42,43 ring-opening 12:83 Sakurai reaction 10:182 S-alkylation 13:145 SE' additions 10:17-25 SN2 cyclization 12:85 SN'-process 11:323 stereoselective cyclization 10:92 translactonization 13:159 trans-sulfenylation 12:69,72 Ulmann reaction 10:640 Wadsworth-Emmons reaction 12:328 Wittig Horner reaction 11:152, 153 Wittig reaction 13:601 Wittig-Horner cyclization 12:292 Wittig-type reaction 12:147 or ester synthesis 10:407 Intramolecular reduction 14:153 Intramolecular reductive amination 12:316 Intramolecular reductive coupling 6:48,52,54 in (-I-)-A9(12) capnellene synthesis 6:48 in dolasta- 1 (15),7,9-trien- 14-ol synthesis 6:52 in isoamijiol synthesis 6:54 Intramolecular ring closure reaction 6:492 Intramolecular trans-ketalization 10:211 Intramolecular type I-"Mg-ene" reaction 6:45,46,76-78 in (___)-A9(12) capnellene synthesis 6:45,46 in (+)-sinularene synthesis 6:76,77
929 Intramolecular vinylogous aldol reaction 24:14,22,23 Intramolecular Wittig reaction 1:234, 235,573 Intramolecular rt-alkylation 6:184,185 Inverse electron demand 4:579,580,604 in Diels-Alder reaction 4:579, 580,604 using enamines 4:604 using enols 4:604 using ketone dithioacetal 4:604 Inversion 1:459 of alcohol center 1:204,205,456, 457,459 Mitsunobu protocol 1:459 Iodination 27:751 of tyrosine 27:751 Iodine pentoxide 1:51 oxidation of indoles to acylindoles 1:151 Iodine-catalyzed 6:139-141,153,154 stereomutation mixtures 6:139-141,154 isomerization 6:141,153,154 Iodocyclisation 10:391 of alkene 10:391 Iodocyclocarbamation 4:126 Iodoetherification 10:21,24 Iodolactone 8:153,154 Iodolactonization 1: 199,204-206, 254,526;13:208,622 by m-chloroperbenzoic acid 11:358,359 by iodine 11:358,359 Iodomagnesium salt 14:750 Iodomethylphenyl sulfide 4:463 alkylation with 4:462 26-Iodoponasterone A 29:19 as synthetic ecdysteroid analogues 29:19 Iodosulfonation 21:384 Iodotrimethyl silane 1:390;11:528 cyclization with 11:109 Ion-exchange column chromatography 19:519 Ionic cycloaddition 5:793 Ipc2BC1 8:476 as chiral reducing agent 8:476
IpcBH2 8:475,476 as chiral reducing agent 8:475, 476 (-)-Ireland alcohol 14:1 ! 9,120 synthesis of 14:119,120 Ireland approach 12:16,17 Ireland-claisen rearrangement 26:1227 kazmaier's modification of 26:1227 Ireland-Claisen rearrangement 3:268, 614;10:416,417,424-425,429; 18:230,231,259;20:67 in nonactic acid synthesis 3:228 of allylic glycolate esters 10:437 of silyl ketene acetal 10:423 Iron pentacarbonyl 14:689,690 Iron tricarbonyl derivatives 1:572 acylation of 1:572 of tropone 1:572 Iso-6-cassine synthesis 29:419 by stereodivergent process 29:419 Isoantibodies 29:542 synthesis of 29:542 Isocyanide group 21:349 biosynthesis of 21:349 Isocyanides 12:113 by alkylation of silver cyanide 12:113 by carbylamine reaction 12:113 by dehydration of N-minosubstituted formamides 12:113 from diphosgene 12:113 from phosgene 12:113 from triphosgene 12:113 isodendrocrepine 12:286 from dendrocrepine 12:286 Isolation 27:164-166 of chelilutine 27:156-166 Isomerism 27:361 of monoterpenoids 27:361 Isomerization 23:195 of azatidine acetates 23:195 R,S Isomerization 6:141 trans, cis Isomerization 6:141,142 cis-Isomerization 6:153,162 Isomerization process 27:350 kinetic characteristics of 27:350
930
Isomerization rates 27:350 of 8'-hydroxyabscisic acid 27:350 of phaseic acid (PA) 27:350 (-)-~-Isoparteine 27:259 conformational studies of 27:258-259 Isophorone 26:307 microbial transformation of 26:307 Isoprenyl- 1,4-naphthoquinones 29:735 biosynthesis of 29:735 Isoprenylation 11:200 by 4-(y,7-dimethylallyl ) tryptophan synthase 11:200 of tryptophan 11:200 Isopropylidene-D-glyceraldehyde 30:469 addition of 30:469 (+)-]3-Isosparteine 27:259 conformational studies of 27:258-259 (-)-Isostegane 29:389 steganes synthesis of 29:389 Iso-swinholide A 26:1229 paterson's synthesis of 26:1229 Italian researchers 29:495 carbaoxirose/carbaoxetoses synthesis by 29:495 Ito cyclization 10:6 Jasmonic acid 27:64,71-73 generation of 27:71,72 4,4'-bis-Jatrorrhizine (v) 27:749 and electron transfer 27:749 Jauch 29:127 sesquiterpenoids drimane-type synthesis by 29:127 Jenkins's synthesis 12:185,186 (+)-Jerusalemine 29:377 allocolchicinoids total synthesis of 29:377 Johnson synthesis 14:681-684 of taxodione 14:681-684 Johnson-Claisen rearrangement 10:428-438
of allylic alcohols 10:428-438 of aldoheptofuranoses 10:432-436 of D-glyceraldehyde derived allylic alcohols 10:436,437 of 4-(3-hydroxy- 1-propenyl) derivatives 10:436-438 of L-lyxofuranose derivatives 10:431,432 Johnson-Lemieux reaction 3:328 Jones oxidation 4:50,456,465,470, 490-492;16:29,30,323,248,235, 514,595,627,641,72,551,558;19:252, 304,320-321 ;21:715 ;22:277 ;26:1209, 1225 Jones reagent 6:17,25,55,78,509,515, 461;12:466,508,613; 14:818;19:173, 428 reaction with stypodiol methyl ether 6:55 Joullie method 10:283 Jourdan-Ullman condensation 13:353-355 Ju-Fang synthesis 6:14 of (+)-polygodial 6:14 of (-)-polygodial 6:14 of (e)-polygodial 6:14 Julia coupling 1:457,458,461-464 Julia olefination 21:397 Julia olefination reaction 16:230 Julia reaction 1:454,456 Julia sulfone 1:463 Julia synthesis 9:356 of 22,23-dihydroavermectin Bib 12:17-19 Kagan' s ether 30:215 cyclisation of 30:215 mechanism of formation of 30:215 Kameda 29:481 validamine synthesis by 29:481 Kato's synthesis 12:181,182 of seco-taxane 12:181,182 Katsuki-Sharpless epoxidation 12:324,481 Kawada's synthesis 30:30-33 of (-)-pironetin 30:30-33
931 Kazmaier's modification 26:1227 of ireland-claisen rearrangement 26:1227 KDN 30:421,422,433,440,444,448,462 configuration of 30:463 preparation of 30:440 synthesis of 30:444,448 total synthesis of 30:462 KDO 30:421,441,449,465,471 Aug6 synthesis of 30:465 debenzylation of 30:441 hydrogenolysis in 30:441 intramolecular cyclization of 30:441 modifications of 30:465 Pettus synthesis of 30:471 synthesis of 30:441 via cobaltoxime 30:449 KDO analogs 30:430 synthesis of 30:430 KDO synthesis 30:448,450,456 photochemical 30:448 radical cross-coupling in 30:448 radical elongation process in 30:450 via exo-glycals 30:456 Kedde reagent 19:753 Kende 29:380,384 steganes synthesis by 29:380,384 Ketalization 6:73,82,83,85 regioselective 11:41,42 trans-Ketalization 4:8,9 acid catalyzed 4:8,9 Ketalized Diels-Alder type adducts 17:458 Keten acetals 4:357 Diels-Alder reaction with 4:357 Ketene complex 16:406 Ketene dithioacetal derivative 12:156, 157 preparation of 12:156,157 Ketene dithioacetal S,S-diozides 6:733 synthesis of 6:33,334 Ketene silyl acetals 4:463,464 Ketene-imine cycloaddition 4:440,470472,474 1,2-diastereoselection 4:472 in Bose reaction 4:440,470
Keten yli de ne- triphe nylphosphorane 4:569,572 o~-Keto acetals 14:500,501 diastereoselective reduction of 1:622 from (-)-(2S,3S)- 1,4-dimethoxy2,3-butanediol LiAIH4reduction of 14:500,501 Michael addition of 14:500,501 with methyl addition of 14:510 [3-Keto acetals 14:497-499 addition of organometallic reagents to 14:497-499 diastereoselective 14:497,498 from (+)-(2R,3R)- 1,4-dimethoxy2,3-butanediol 14:497-500 from (R,R)-2,4-pentanediol 14:497,499 LiAIH4-reduction of 14:499,500 NaBH4-reduction of 14:500 [3-Keto esters 4:436,439 in asymmetric hydrogenation 4:439 [3-Keto thioester 11:195 reduction of 11:195 4-Keto-5-methyl-trans-decalins 9:30 [3-Keto-acid 8:384 decarboxylation of 8:297 3-Ketoadociaquinone A 17:33 13-Ketoamide 12:162 asymmetric hydrogenation of 12:162 4-unsubstituted [3-1actam from 12:162 o~-Ketoamide 11:286 from aminoketal 11:286 [3-Ketoester enolization 14:734 5-Keto-imine intermediate 6:480,481 benzodiazonin-3-one from 6:480,481 ~-Ketol rearrangement 11:53,54 Ketone 5:782,783 formation by epoxide rearrangement 5:782,783 Ketone reduction 1:415,417 Luche's conditions 1:415,417 stereoselective 1:415,417 to equatorial alcohol 1:415,417
932 with axial hydride attack 1:413, 415 with NaBH4-CeC13 1:413,419 Ketosugars 4:353,354 Grignard reactions with 4:353, 354 13-Ketosulfoxides 4:502 reaction with enolate anions 4:502 reduction of 4:502-504 synthesis of carbohydrates 4:504-512 synthesis of macrolides 4:513-512 ~-Keto-13,y-unsaturated acetal 14:496 addition of Grignard reagents 14:496 Khan's method 21:742 for synthesis of chalcone 21:742 Kibayashi's group 29:432 marine alkaloids synthesis by 29:432 Kinetic characteristics 27:350 of isomerization process 27:350 Kinetic resolution 1:508,698;3:23, 19:478 by Sharpless epoxidation 4:342 of secondary 2-furylcarbinols 19:478 under Sharpless epoxidation conditions 19:478 Kirk-Petrow reaction 10:409 Kishi synthesis 13:436-442,443,457, 458,461 of mitomycins 13:4-10,25,26,29 Kishi's retrosynthesis 26:1231 of onnamide 26:1231 Kishi's rule 1:404,130,163,167,168,171, 175;4:178,181,183,184,188,197,202, 203,705 Kishi's-model 4:503,504 Klemer fragmentation 3:201,202 Klemer-Rhodomeyer reaction 1:510, 511 Klyne's rule 26:8 of molecular rotation 26:8 Klyne-Hudson rule 15:207 Knapp and Sharma 29:214 miltirone synthesis by 29:214
Knoevenagel condensation 6:53,67,68, 316,320,328,331,334;24:36,37 in 14-epi-upial synthesis 6:67,68 Knoevenagel condition 11:140 Knoevenagel cyclisation 9:341 Knoevenagel reaction 13:109 Knoevenagel-Doebner condensation 24:717,718 Knoevenagel-type reaction 7:475 Kocienski-Lythgoe condensation 4:602,603 Kocienski-Lythgoe-Julia olefination reaction 11:393-395 Kodo-cytochalasin-1 and 2 15:353 Koenigs-Knorr condensation 3:199 modification of 3:199 Koenigs-Knorr coupling (AgzCO3AgCLO4) 1:419,420 Koenigs-Knorr procedure 10:571 Koenigs-Knorr reaction 8:206,258, 359,363 Koenigs-Knorr synthesis 10:466 Koga 29:386 steganes synthesis by 29:386 Koga's method 11:241,242 of asymmetrization 11:241,242 of G-symmetric ketones 11:241,242 Kolbe reaction 9:371 Konevenagel-type reaction 11:139 K6nigs-Knorr coupling 21:170 Kozikowski approach 12:20-22 for avermectin oxahydrindene subunit 12:20-22 Kozikowski's nitrile oxide 12:21,22 Kozikowski's retrosynthetic analysis 13:588 Krapcho decarboxylation 18:246 Krapcho's thermal dealkoxycarbonylation 24:39 Kraus method 6:225,226;11:129 Krebs cycle 7:112,117,387 Krebs cycle enzymes 11:197 Krebs tricarboxylic acid cycle 6:252 Krohncke reaction 20:602 Krohncke's procedure 6:513 Krow 29:384 steganes synthesis by 29:384
933 Kuehneromycin A 29:128,129 synthesis by Jauch 29:159 synthetic strategies of 29:129, 130 total synthesis of 29:148 transition states in synthesis of 29:161 Kuehne's synthesis 14:831-849 of vinblastine 14:831-849 of vincristine 14:831-849 Kuhn-Roth oxidation 11:210 Kutney's synthesis 14:806-821 of vinblastine 14:806-821 of vincristine 14:806-821 Kuwajima's B-ring cyclization route 12:190 Lactam carbonyl 3:474 selective reduction of 3:474 [3-Lactam compounds 12:155-159 from I3-amino acid 12:155-159 synthesis of 12:155-159 Lactam sulfoxide 3:109 cyclization of 3:109 (4R)-Lactone 8:305,306 anti addition of 8:305,306 Lactone 30:17,457 hydroboration-oxidation reaction of 30:457 hydrogenation of 19:469 methylation of 19:469 synthesis of 30:17 (4S,5S)-Lactone 8:296 S-Lactone 8:298,306 syn addition of 8:306 y-Lactone 19:470 reduction of 19:470 Lactone annulation 13:29-31 Lactone Claisen rearrangement 13:544, 596 Lactone methyl-isomerase 8:300 Lactone rearrangement fragmentation 3:96 Lactone synthesis 13:615-626 asymmetric synthesis of 13:621, 622
Lactone triflate 10:60 ring contraction reaction 10:605 to oxetane-2-carboxylate 10:605 Lactone unit 11:345-347 construction of 11:345-347 model studies on 11:345-347 of compactin and mevinoline 11:345-347 Lactonisation 12:157,158 acid-catalyzed 12:157,158 by Gerlach's procedure 6:542, 543 of N-acetyl muramic acid 6:389, 390,395 of -hydroxy-acids 8:233 with pyridinium acetate 11:84,85 Lapachol 29:734 biosynthesis of 734 Lauryl chloride 6:429 protection with 6:429 Lawsone 29:736 biosynthesis of 29:736 LDL peroxidation 30:224 induction by AAPH 30:224 induction by Cu 2+ 30:224 Lead tetraacetate 1:439 oxidation of diol 1:439 oxidation of ring C of yohimbine 1:158,439 glucuronide linkage cleavage by 7:156-158 Lead tetraacetate oxidation 5:788 Lemieuix oxidation 18:171 Lemieuix-Johnson oxidation 4:592,593; 10:591-592;13:613;18:81 Lemieux-Nagabhushan reaction 14:145 Leucomelone 29:299 synthesis of 29:299 L~vy and co-workers 29:373,401 rhazinilam synthesis by 29:373, 401 Lew and Kim 29:488 thiocarbapyranoses synthesis by 29:488 Lexitropsins 5:567,578 Ley synthesis 12:22-24 of avermectin Bla 12:22-24 Ley's procedure 6:13 in (_+)-polygodial synthesis 6:13
934
Licochalcone 21:740-744 synthesis of 21:741-743 Lignans 24:215,228-232,739-798 synthesis of 24:739 transformations of 24:739 Linoleic acid 27:68 lipid peroxidation of 27:59,68, 85,504,505 Linolenic acid 27:70 generation of 16S-hydroperoxy9Z, 12Z, 14E-octa-decatrienoic acid (l 6S-HPOTE) from 27:70 generation of 9S-hydroperoxy10E, 12Z, 16Z-octadecatrienoic acid from 27:70,71 Lipid hydroperoxides (LOOHs) 27:59, 67,68, 73,78 degradation products of 27:68 Lipid peroxidation 27:59,68,85,504,505 of linoleic acid 27:68 Lithiated trimethylsilylacetonitrile 1:311,312 Lithiation 5:827 of 2-methoxy-N, N-diethylbenzamide 5:827 of 3-methoxy-N, N-dimethylbenzylamine 5:828,829 with sec-butyllithium 5:827,828 1-Lithio glycals 10:345 by direct lithiation 10:345 from tributyltin 10:345 2-Lithio-2-phenyl-6-heptene 8:7,8 synthesis of 8:7,8 2-Lithio-3,3-diethoxy- 1-propene 12:36, 40,43 Lithiodianion-imine condensation 4:433,443-448,450,464 2-Lithiofuran 30:469 addition of 30:469 Lithioglycal 10:346 N-Lithioimidazolidines 1:349-351 anionic cycloreversion of 1:349-351 2-azaallyl anions from 1:349-351 Lithium/4,4'-di (tert. butyl) biphenyl (DTBBP) 11:309 Lithium aluminium hydride 22:288,293
Lithium di (c~-ethoxyvinyl) cuprate addition of 12:25 BF30Et2 promoted 12:25 to A2'3 enone 12:25 (E)-Lithium enolate 30:25,469 oxidation of 30:469 Lithium hexamethydisilazide (LHMDS) 24:9,10 Lithium isopropylcyclohexylamide (LICA) 10:410 Lithium methylcrotyl aluminate 6:298, 299 condensation with 6:298,299 Lithium organocuprates 4:555,556 1,4-addition 4:555,556 Lithium organyls 4:556-558 1,2-addition 4:556-558 Lithium triethyl borohydride 11:423 reduction with 11:83,84 Lithium tri-sec butylborohydride (Lselectride) 11:234 Liu-Kulkarni synthesis 6:43,44 LL-Z 1271 c~ 28:495 synthesis of 28:495 L-malic acid 30:38,39 (2S,3S)-2-ethyl-3,4-isopropylidene dioxypropan- 1-ol from 30:39 role in (-)-pironetin synthesis 30:38 LO" radicals 27:78,79 generation of 27:78 Lombardo methylenation 6:209 Lombardo reagent 11:40,41 methylenation with 11:40,41 Lossen rearrangement 26:1074 Low density lipoprotein 27:846 chemical degradation of 27:846 Lowary and Callam 29:457 carbafuranose synthesis by 29:457 Low-valent titanium 4:521-535 from reductive elimination 4:521-535 Low-valent titanium reagent 11:364 keto aldehydes with 11:364 preparation of 11:364 Luche reaction 1:474
935
Luche reduction 14:126,19:372-373 Luche-type reduction 4:130 with ct,~-unsaturated ketone 4:130 Lundt and Horneman 29:456 carbafuranose synthesis by 29:456 Lupeol palmitate (lupeol hexadecanoic acid ester) 29:587 synthesis from lupeol 29:587 Lupinyl moiety 27:285 L-xylo-heptulosonic acid 30:434 stereoselective synthesis of 30:434 Lycogalic acid 29:231 from oxidative dimerization of 3-(indol-3-yl)pyruvic acid 29:231 synthesis from methyl 3-(indol3-yl)pyruvate 29:231 Macrocarbocyclic rings 8:16-18 synthesis by titanium 8:16-18 with TIC13/Zn-Cu 8:16-18 Macrocyclic [2,3]-Wittig rearrangements 8:196 Macrocyclic reaction 8:175-201 Macrocyclic transannular reaction 8:187-201 conformational control in 11:152-163 of geranyl geranyl pyrophosphate 11:24 with Hanessian's epi-merization 12:28 Macrocyclic trichothecenes 30:751 inhibition of protein synthesis 30:751 Macrocyclization 4:591 ;8:21 ;11:24,152, 158,163;12:28 by allychromium species 3:81 by dicarbonyl coupling 3:80 by Michael additions 3:83 by Nicholas reactions 3:83,84 by transannular acylation 3:81 for synthesis for 8-membered rings 3:80-84 polymer supported 3:82-83
transition metal mediated 3:80, 83 Macroheterocyclization 16:423 palladium mediated 16:423 Macrolactamization 25:712 Macrolactonization 1:445,452,453,461, 462,464,465 ;8:233-242;9:246,247, 290;12:244;13:115,20 Macrolide antibiotics 29:321 biosynthesis of 29:322 Madelung reaction 1:52 Magnus 29:389,390 steganes synthesis by 29:389,390 Magnus's synthesis 14:821-830 of vinblastine analogues 14:821-830 of vincristine analogues 14:821-830 Maillard reaction 13:317-319 Majetich et al. 29:215 miltirone synthesis by 29:215 Majetich synthesis 6:32,33 of perforenone 6:32,33 Mallory stilbene photocyclization 3:305 Mannans and oligomers 26:1158 synthesis of 26:635-637,642 Mannich base methiodide 14:406-408 condensation of 14:406-408 with thujone 14:406-408 Mannich condensation 6:39 in (+)-stoechospermol synthesis 6:39 Mannich reaction 1:244;6:39;9:332; 13:473;16:481 intramolecular 14:746 of dimethyl t~-ethylmalonate 14:850 with diethylamine 14:850 with vitamin 4:715 Mannich-Aldol condensation 12:293 Manool 25:253,254,259 biosynthesis of 25:253,254,259 Manoyl oxide 25:245,248-250,253-255 fragmentation of 25:255 Manzamenone K 23:204,211 biogenesis of 23:204,211 Manzamines 24:573,575,614-616, 621-645
936
biosynthesis of 24:573 synthesis of 24:614,615, 623-645,669 Marfat-Helquist annulation 13:11,12 Marine alkaloids synthesis 29:427 by Kibayashi's group 29:432 enantioselective 29:426 Marine bioactive compounds 24:537-672 biochemical aspects of 24:573-672 structures of 24:573-672 synthesis of 24:573-672 Markovnikov orientation rule 22:277 Marschalk condensation 1:595 Marschalk reaction 4:346,347,350,352; 14:5,12 Marshall synthesis 6:73;30:19-22 of (-)-dictyolene 6:27 of dihydrospiniferin- 1 derivative 6:72,73 of (+)-diseodermolide 30:19-22 Martin reagent 13:601 Martin sulfurane reagent 6:204,205 Matteson method 26:1221 for dihalomethylithiation insertion 26:1221 McCasland 29:466 pyranoid carbasugars synthesis by 29:466 McFayden-Stevens reduction 8:273 McLafferty rearrangements 2:6;22:371 McMurry coupling 11:337,354 intramolecular 11:343,363,364 McMurry cyclization 11:27 McMurry reaction 9:250,255 intramolecular 11:337 McMurry reagent 13:601 CPBA oxidation 29:373 in rhazinilam synthesis 29:373 MCPBA oxidation 8:216 Mechanics 6:316,320 of acetal derivatives formation 6:335,336 of cyclization 6:314,345 Mechanism 4:638,639 of C (8) bromination of camphor 4:638,639 of C(9) bromination of camphor
4:633,634 of biomimetic olefin cyclization 1:671-674 of cyclization 7:335-338, 358-360 of Diels-Alder reaction 4:579, 580 of hydrogen phosphite method 4:277 of lithio dianion-imine condensation 4:444-447 ofphosphite method 4:272 ofphosphotriester method 4:270 Mediated oxidation 26:991 ferrihemoglobin 26:985,986,991 Medium ring ethers 10:201 biological activity of 10:201 synthesis of 10:201-239 Meerwein-Pondorf-Verley-Oppenauer 14:481 reaction intramolecular 14:481 Meerwein's reagent 8:205;12:289, 20:426 Meerwein's salt 12:300,305,320 Meisenheimer rearrangement 6:468 of allocryptopine N-oxide 6:468 of cis-(+)-laudanosine N-oxide 6:468 [1,2]-oxaza ring formation by 6:472 Melanin 26:1019 biosynthesis of 26:1019 Melatonin 30:369 synthesis of 30:369 MEM 6:558,559 protection with 6:558,559 MEM ethers 1:558 deprotection TMSC1/NaI 1:558 for alcohol protection 1:558 MEM-directed organometallic addition 12:201 Menaquinone- 1 29:736 biosynthesis of 29:736 synthesis of 29:226 2-Mercaptobenzothiazole 26:162 synthetic derivatives of 26:162 Mercaptolysis 6:279,280,282-286 Mercaptomethylation 6:323-325 Merck method 12:135
937 Merck procedure 4:453 for carbapenem formation 4:453 mercuric salt method 4:22 for nucleoside synthesis 4:22 Mercuric acetate 1:125 oxidative cyclization 1:133 Mercuric amidation 14:568 Mercury (II) triflate 1:657 formation of 1:657 Mercury (II) triflate/N,N-dimethylaniline complex 1:657,658 Mercury (II) trifluoromethanesulfonate 1:656 cationic olefin cyclization 1:656 Mercury group 1:659 replacement by OH group 1:659 Meridinol 24:752 synthesis of 24:752 Mesylate elimination 1:477 Mesylation 4:16,126,442;6:9,10,71,76, 77,229,289,290,390,548-550; 10:322,323 ;19:147,371 axial 1:415,417 of alcohol 19:494 of allylic alcohols 4:16 of primary alcohol 19:477 Metabolic inactivation 27:322 of abscisic acid 27:322 Metal acetates 11:116 Metal complexes 4:720-722 of ascorbic acid 4:720-722 Metal enolates 3:409 contact ion pair 14:497 from t~,~-disubstituted ethyl ester 14:497 Metal reduction 6:541,542 of vic-phenyl thiobenzoate 6:541,542 with sodium naphthalenide 6:541,542 Metalated arenes 11:140 Metalated sugar 11:140 Metallation 5:822,823 with n-butyllithium 5:822,823 Metallation reactions 4:386-389 in basic media 4:386-389 N,N-disubstituted amides with 4:389
N,N-disubstituted benzyl amines with 4:389 N-Metalloaziridines 1:348,349 2-azaallyl anions from 1:348,349 ring opening of 1:348,349 Metalloenamines 4:5-7,22 from 2-azadienes 4:7,10-14,17 Metallo-ene reaction 3:21;16:418,437 intramolecular 16:437 Metalloorganic addition 4:124 to t~-amino aldehydes 4:124 Metha and Mohal 29:462 carbafuranose synthesis by 29:462 carbaaldopyranoses synthesis by 29:470 13-Methallyltriphenylstannane 12:478 13-Methallytri-n-butylstannane 12:478 Methane sulphonate 6:126,127 DBU reaction with 6:126,127 Methanesulfonyl chloride 8:27-30 Methaniminium methylide 1:336,337 Methanolysis 6:276,390-395;19:42,442; 26:65 acid-catalyzed 14:563,564 alkoxyacrylate from 14:563,564 of (Z)-9-hexadecenoic acid 26:70 of 10-hydroxydecanoic acid 26:65 (4E,7S)-(-)-7-Methoxy-4-tetradecenoic acid 26:78 total synthesis of 26:78 (Z)-2-Methoxy-5-hexadecanoic acid 26:77 total synthesis of 26:77 Methoxybenzene 30:146,149 Birch reduction of 30:146 synthesis from 30:149 p-Methoxybenzyl (PMB) ether 30:8 oxidative cleavage of 30:8 (R)-3-p-Methoxybenzyloxy-2methylpropionaldehyde 30:10 aldol condensation of 30:10 Methoxybrominations 12:419-421 diastereoselective 12:419-421 of 3-[(IS)-2-exo-alkoxy- 1apoc amphan ec arbo nyl ]-2-
938 oxazolones 12:420,421 of 3 [(IS)-ketopinyl]-2-oxazolone 12:420,421 Methoxycarbonyl 6:540 as activating group 6:540 (R)-2-Methoxyhexadecanoic acid 26:78 total synthesis of 26:78 Methoxylated arylpyruvic acids 30:221 reaction of 30:221 Methoxylation 1:247 anodic 1:247 Methoxymercuration-demercuration 1:510 Methoxymethyl group 6:282,283 protection with 6:282,283 Methoxyphenyl 30:213 demethylation of 30:213 2-Methoxyphenyl acetones 30:222 cyclisation of 30:222 2-Methoxyphenylpyruvic acid 30:221 reaction with boron tribromide 30:221 Methoxyselenylations 12:421,422 of 3- [-2-exo-alkoxy- 1apocamphanecarbonyl]-2oxazolone diastereoselective 12:421,422 Methyl (Z)-2-methoxy-6-hexa decenoate 26:75 total synthesis of 26:75 (S)-(+)-Methyl 3-hydroxy-2-methylpropionate 30:17 (+)-discodermolide 30:17 in synthesis of 30:17 role in (-)-pironetin synthesis 30:30 or 3-ulosonates 30:459 stereoselective formation of 30:459 (+)-Methyl 4,6-O-benzylene-oc-Dglucopyranoside 30:30 role in (-)-pironetin synthesis 30:30 Methyl ester 27:346 8',8',8'-trifluoro-ABA from 27:346 l'-Methyl ether 27:341 ABA of 27:341
Methyl ketones 11:130 Claisen condensation of 11:130 from ester 11:130 synthesis of 11:130 Methyl phosphonates 13:271-281,287, 290 by phosphoramidite method 13:272 by phosphotriester method 13:272 diastereoselective synthesis of 13:279,280 Methyl ~-tolyl 27:752 of sulfoxidation 27:752 11-Methyl- 12-octadecenoic acid 26:69 total synthesis of 26:69 6-Methyl-2-heptanone 26:65 wittig reaction of 26:65 7-Methyl-2-heptanone 26:65 wittig reaction of 26:65 5-Methyl-2-hexanone 26:66 wittig reaction of 26:66 2 C-Methyl-4or arba- ~- Darabinoaldofuranose 29:459 carbafuranose synthesis of 29:459 (R)-22-Methyl-5,9-octacosa-dienoic acid 26:87 total synthesis of 26:87 7-Methyl-6(E)-hexadecenoic acid 26:71 total synthesis of 26:71 7-Methyl-6-octadecenoicacid 26:72 total synthesis of 26:72 ~-Methylaspartate 26:1225 panek's synthesis of 26:1225 Methylation 19:134 chemoselective 19:92, deoxygenative 19:519 Hakamori method 2:336 with trimethyl orthoformate 1:448,449 N-Methylation 6:478,491,492;19:321 of 1,4-dideoxy- 1,4-imino-Lallitol 7:41-43 of indolines 4:79 O-Methylation 6:76,77 of coumarins 5:516-520,
939 of lignans 5:525-532 in (__)-sinularene synthesis 6:76,77 13-Methylation 8:192,193 C-Methylation 7:207 in Artemisia austriaca 7:207 Methylenation 8:26,29,30 with Lombardo reagent 11:40,41 ~-Methylenation 8:21,29;10:13,17,25; 13:33 7-O-Methylrosmanol (abietane diterpene) synthesis 29:575 from carnosolic acid 29:575 (E)-5-Methyltetradec-4-enal 26:72 wittig reaction of 26:72 Meyer 29:394 steganes synthesis by 29:394 Meyer et al. 29:191 carnosic acid synthesis by 29:191 Michael (1,4-addition) reaction 147-199 Michael acceptors 16:650;18:315,329, 334,339,369 c~,]3-unsaturated orthoesters 3:146 Michael addition 5:181,182;6:5-7,74, 75 ;8:224,277 ;9:343,347 ;10:61,164, 183,412;11:96,97,123 ;14:5,37,39,42, 118,274;15:272;16:30,155,424,582, 700;18:10,63,81,333,343,355,374, 369,378;26:1237 2-amino alcohol by 12:411,413 asymmetric 14:510 base catalyzed 14:521 carbocycles 8:409-428 diastereoselective 11:286 enantiospecific 16:221,262,613 in the synthesis of 8:409-428 intermolecular 14:524 intramolecular 3:83;10:51; 11:312;12:17;14:521,523,524, 736;16:695 of alcohol 16:104 of alkoxides 12:411,413 of diene 16:548,595 of enolates 10:407 of levoglucosenone 14:271,272 of methyl group 10:414,415
of MT-sulfone 6:337,347 of natural products 8:410-412 of nitroalkane dianion 1:311, 312 of trimethylsilyl ketene acetal 10:353 of ~-ethylidene-y-lactone 10:405,406 of c~-formyl-~-phenyl acetic acid 10:408 of o~-keto acetal 14:510 stereoselective 1:489,490 Stork modification of 10:185 tandem 4:556,557 to nitro olefins 10:407;12:411, 413 to ]3-methylated enone 10:414, 415 with methyl vinyl ketone 14:510 Michael cyclization 16:437 intramolecular 14:552 Michael initiated ring closure 24:769, 770 for isopicropodophyllone analogues 24:769,770 retro-Michael reaction 26:110 Michael reaction 6:70,71 ;9:435,437, 516;11:31,38,39,41,42;13:29,30,180, 398,404-406,417,418,437,440,448, 458,609,618;16:494;24:7 aliphatic acceptors 4:705,706 alkenoylcyanide acceptors 4:709-711 asymmetric 14:551-567 chiral building block from 14:551-567 cyclic ene-dione acceptors 4:709 cyclic enone acceptors 4:707-709 intramolecular 14:551-567 reaction mechanism of 14:551-567 with quinone methides 4:712 with vitamic C 4:705-715 Michael type addition 18:65,269,302, 303,305,307,309
940
of nucleophilic glycosyl radical 11:464 [3-amino ketone 8:286 Michael-Aldol reaction 3:132-143 Michael-Arbuzov transformation 13:273 Michael-induced cyclization 14:755, 756 Michaelis-Arbuzov reaction 4:68 Michael-Michael construction 12:203 Michael-type acceptors 12:99 Michael-type addition 8:286 Michael-type quinolizidine ring closure 29:427 reaction pathways of 29:431 role of piperidine in 29:427 stereochemical course of 29:488 stereochemistry of 29:427 Wittig-Horner reaction in 29:427 Microbial hydroxylation 9:416 Microbial oxidation 18:430-432 of arenes 18:430-432 Microbial reduction 4:493 of keto acids 4:493 by Baker' s yeast 6:13 of K l o e c k e r a m a g n a 6:13 Microbial transformation 9:416;13:298 carbaaldopyranoses synthesis by 29:469 of limonene 16:208 of isophorone 26:307 of xanthurenic acid 26:991 of 8-hydroxyquinaldic acid 26:991 Microbiological reduction 13:556 of racemic dione 13:556 Microozonolysis 6:455 Microsomal oxidation 19:188 Miltirone synthesis 29:212 by Banjerjee et al. 29:215 by Knapp and Sharma 29:214 by Majetich et al. 29:215 by Nasipuri and Mitra 29:212 by Snyder et al. 29:214 Mitsonobu epimerization 24:63,64 Mitsonubu activation 3:328 Mitsonubu alkylation 3:313 Mitsunobu condensation 18:88 Mitsunobu conditions 16:461
Mitsunobu coupling 12:448 of 3,4-dimethoxyphenethyl alcohol 12:448 of 1-methyloxazolidien-2,4-dione 12:453 Mitsunobu displacement reaction 12:281 Mitsunobu inversion 1:695,697,698; 4:449,459;6:553,554 ;13:499,502; 18:7,237,246,259,281,470,893,903 Mitsunobu procedure 1:456;14:182 ring closure by 11:10 Mitsunobu reaction 1:205;4:86,456,457, 478,515,519;6:294,295;10:603; 11:404;12:305,312,319,468;13:201, 443,485;14:15,275;16:79,350; 18:174,217,235,471 with phthalimide 11:236 Mitsunobu reaction 22:283;24:36-37; 26:1236;30:20,38 Mniopetal E synthesis 29:131,133 approaches for 29:133 decomposition in 29:139 IMDA reaction of 29:1,3,9decatriene derivative in 29:131 via intramolecular Diels-Alder reaction 29:139 NOE experiments of IMDA adducts in 29:140 plausible transition states of 29:141 recovery of substrate in 29:139 use of Wittig reaction in 29:131 Mniopetals 29:128 total synthesis of 29:148 MO4 27:771 tautomerization of 27:771 Modified Eschenmoser method 3:482 Modified Eschweiler-Clarke conditions 6:476 Modified Schollkopfs procedure 15:443 Moffatt oxidation 12:325,335;14:814, 815 Molecular rearrangements 5:792-794 of perezone 5:792-794 of sesquiterpenes 5:794-800 of grandiflurenic acid 19:389-410
941
Molecular rotation 26:8 Klyne's rule of 26:8 Monoalkylation 6:341 of MT-sulfone 6:330,331,339, Monobenzylation 11:253,254 Monochlorinated sulfoxide 6:310 c~-alkoxysulfoxide from 6:310 chemcial reactions of 6:310 epoxysulfoxide from 6:310 from N-chlorosuccinimide 6:310 from sulfoxides 6:310 Monoterpenoids 27:361 isomerism of 27:361 Monti 29:458 carbafuranose synthesis by 29:458 Mori and Mori 29:182 pisiferic acid synthesis by 29:182 Mori synthesis 13:500 of azitidinone derivative 13:500 Mori-Matsui synthesis 14:667-670 to taxodione 14:667-670 Mosher ester 11:361 ;12:478 absolute configuration of 13:77 Mosher's (+)-MIPA ester 1:370,371 Mosher's method 15:76;17:264,271,276 Motherwell 29:399 steganes synthesis by 29:399 MT-sulfone 6:329 acidity of 6:329 alkylation of 6:334 dialkylation of 6:332 from DMSO 6:329,330 Michael addition of 6:337-339 monoalkylation of 6:330,331, 339 organic synthesis with 6:329,330 properties of 6:329 synthesis of 6:329,330 Mukaiyama ADD reagent 10:23,24 Mukaiyama aldol process 19:203 Mukaiyama aldol reaction 18:292; 30:17,42,43 Mukaiyama condensation 10:187 intramolecular 10:181,182,218 Mukaiyama conditions 12:244 Mukaiyama-Michael aldol condensation 16:664 Mukaiyama's protocol 11:289,296,297
Muzigadial 24:182-185 synthesis of 24:182-185 Myles' s synthesis 30:10-12 of discodermolide 30:10-12 Nagata hydrocyanation 11:87 Nagata's reagent 16:13 Nagilactone F 28:499 synthesis of 28:499 Nagilactone F 28:502 total synthesis of 28:502 l-Naphthylacetone 30:218 Nasipuri and Mitra 29:212 miltirone synthesis by 29:212 Natural (-)-steganone 29:392 steganes synthesis of 29:392 Natural bioactive alkaloids 27:778 synthesis of 27:778 Natural bridged biaryls 29:355,356 synthesis of 29:355,356 Natural steroid 30:504,505 synthesis of 30:504 Natural steroids synthesis 30:504 of vitamin D analogues 30:504 Nazarov cyclizations 3:11;13:34,35 BF3-OEt2 mediated 10:412 in (-+-)-A9(12) capnellene synthesis 6:43 of (+)-limonene 10:412 with BF3-Et20 8:242 Nazarov reaction 14:592,611 Nazarov's reagent 14:734 Nef reaction 10:464;14:39;19:120,141, 146,152,153,173 reductive 14:633,634 Negishi coupling reaction 30:13 Neighboring group participation 1:204,205 acetamide assisted displacement 1:204,205 for hydroxyl inversion 1:427,428 Neolignans 30:219 biosynthesis of 30:219 Neu5Ac 30:425,440,445-448,460,463, 468 biosynthesis of 30:425 Grignard reaction of 30:445-448 preparation of 30:440,463
942
role of phosphoenolpyruvate 30:425 synthesis of 30:445-448 total synthesis of 30:460 Neu5Ac aldolase catalysis 30:428 synthesis of KDO by 30:428 Neu5Ac analogs 30:426 preparation of 30:426 Neu5Ac precursor 30:461 and stereospecific hydroxylation 30:461 Neuraminic acid 30:420 deaminated form of 30:420 Neuropeptide analogues 27:798 N-Glycoylneuraminic 30:427 synthesis of 30:427 N-Heterocyclic ring 27:782 aromatization of 27:782 Nicholas reactions 3:83,84 Nichora's method 12:175 Nickel boride 3:472 desulfurization with 3:472 Nine-carbon sugars 4:179 by ascent of sugar series 4:179 osmylation of 4:180-182 synthesis of 4:179 Wittig olefination of 4:180 Nine-membered rings 3:77 by Claisen rearrangement 3:77 by intramolecular DielsAlder/ozonolysis 3:79,80 by ring expansions 3:76 from 1,3-diol monotosylates 3:73,74 synthesis of 3:73,111 ;6:472-482 by ring contraction 6:474-482 of ring destruction 6:475,482 by ring interconversion 6:472-482 Nishimura's catalyst 6:80,81 Nishizawa complex 16:665 Nitrene insertion 1:8,9,167 Nitrile oxide cyclization 12:20-22 intramolecular 12:20-22 isonitramine by 14:745 Nitroaldol (Henry) condensation 1:408, 409,417,418 KF catalysed 1:417,418 Nitroaldol condensation 19:159
Nitroaldol reaction 1:427,428 p-Nitroanilide 30:834 hydrolysis of 30:834 Nitroblue tetrazolium reduction 20:515 Nitronate addition 1:505 Nitrone 1:230,254,277 1,3-dipolar cycloaddition of 1:230,254,277 dibenz [c,g] azonine derivative from 6:474,475 from cis (trans) canadine Noxide 6:474,475 photolysis of 6:474,475 synthesis of 1:230 Nitrone cyclization procedure 14:737 Nitrone cycloaddition 1:37-375;12:290, 291 asymmetric 1:374,375 intramolecular 14:744 nitramine synthesis by 14:744 Nitrone-based synthesis 6:442 Nitrone-olefin 11:283 1,3-dipolar cycloaddition of 11:283 intramolecular 11:283 Nitro-olefins 12:411,413 alkoxides 12:411,413 2-amino alcohols from 12:411, 413 [4+2]Nitroso cycloaddition 1:378 Nitroso Diels-Alder reaction 1:378,380, 381,383 intramolecular 1:385-392 N-methylmaysenine 21:445,446 synthesis of 21:445,446 NO + 2:6 reaction with alkenes 2:6 reactions with hydrocarbons 2:4,5 NOE experiment 27:338 of abscisic acid 27:338 Nonenzymic 27:81 induced linoleic acid oxidation of 27:81 unsaturated epoxy hydroxy acids by 27:81,82 Norrish cleavage 8:207 of alkylphenacyl sulfides 8:207
943
Norrish II reaction 8:128-131 of gibberellin aldehyde ester 8:128-131 Norrish II process 7:147 Norrish reaction 20:74 Norrish type 1 photo-cleavage 19:35 upon UV irradiation 19:35 Norrish type II photocyclization 14:659-664 Norrish type II photofragmentation 14:659-664 in carbohydrate 14:659-664 Norrish type II reaction 4:419,420; 14:645-665 Noyori BINAL-H reagents 10:22-24,37 Noyori procedure 11:96 Noyori Ru-BINAP catalyst 13:503 Nozaki reaction 12:13 intramolecular 12:13 Nozaki-Hiyama reaction 30:24 Nozaki-Kishi coupling reaction 30:8, 10,11 Nozaki-Oshima methylenation 6:185 Nozaki-Oshima reagent 6:189 deuterated 6:189 Nozaki's reagent 14:637 N-substituted NeuAc derivatives 30:427 preparation of 30:427 N-sulfonation 11:291 of 3-indolyacetic acid 11:291 Nuclear Overhauser effect (NOE) 27:335 of abscisic acid 27:336 Nucleophile 16:399 Schollkopf type 16:403 Nucleophilic addition 16:439;19:527 2-amino alcohol by 12:411,413 of 2-1ithio-3,3-diethoxy- 1-propen with N bulc 12:36 of ketonucleosides 19:527 of organolithium reagents 12:411,413 of o~-alkoxydimethyl hydrazones 12:411,413 to s-amino aldehydes 12:411, 414 intramolecular 16:439 to carbonyl compounds 12:36 by allyltin derivatives 11:442,
443 by carbanion reagents 11:439-443 by vinyl carbanions 11:440,441 of chiral ~-keto acetals 4:330-332 of nonylmagnesium bromide 19:493 Nucleophilic agents 19:121 Nucleophilic conjugate addition 4:479 to 2-(1 '-hydroxyethyl) propenoates 4:479 Nucleophilic displacement 19:68,191 intramolecular 16:426 of allylic acetate 16:426 Nucleophilic epoxidation 19:167 Nucleophilic substitution 14:438-445 Lewis acid-mediated 14:484 of acetals 14:484 N-Unprotected Neu5Ac 30:427 preparation of 30:427 O, O-Dimethylmalekulatine 30:584 from (+)-malekulatine 30:584 Octalin coupling reagent 13:586 Octulosonic bicyclic precursors 30:473 synthesis of 30:473 O-Glycoside 10:344,370-380 intramolecular rearrangement 10:379 stereoselective synthesis of 10:340 1~,25(OH)2D4 30:495,499,500,501,504 synthesis of 30:501 Ohno's cyclization method 4:466,467 Ohno's lactone 8:148,149 synthesis of 8:148,149 Ohtsuk-Tahara synthesis 14:677,678 of taxodione 14:677,678 Oidiolactone C 28:505 synthesis of 28:505 Oishi's macrocyclic lactam contraction 12:187 Olefin 12:151,152 reduction of 12:151,152 with high stereoselectivity 12:151,152 oxidative cleavage of 30:43
944 cis-Olefin 14:569
benzylation of 14:569 from propargyl alcohol 14:569 Olefin conjugation 1:442 with DBU 1:442 Olefin cyclization 1:655-673 biomimetic 1:655-673 using mercury (II) triflate/amine complex 1:655-673 Olefin isomerization 4:49 of allyl acetates 4:49 with Pd (MeCN)2 C12 4:49 Olefin metathesis 3:18 Olefin stain 12:207 trans-Olefin 14:570 E-allylic alcohol from 14:570 benzylation of 14:570 Olefin-arene photocyclization 3:28 Olefinic dioxolane acetal 14:471 cyclization of 14:471 from (2R,3R)-2,3-butanediol 14:471 Olefin-ketocarbene cyclization reaction 6:41 in (_+)-isocycloeudesmol synthesis 6:41 Olefins 1:451,453;4:503,504;7:390, 9:315;13:313;27:749,752 conversion to chlorohydrins 1:451 isomerization 1:453 with Rh (PPh3)3 C1 1:453 halogenation of 27:749,752 Oligomerization 12:189 base-catalyzed 14:271,272,274 of levoglucosenone 14:271,272, 274 of PBG 9:595 Oligoribonucleotide synthesis 4:303 by phosphite method 4:303 by H-phosphonate method 4:304,305 by phosphotriester method 4:301-303 protecting group for 2'-hydroxy 4:296 Oligosaccharidic moiety 27:524,673 of saponins 27:673
Olive oil 27:697 hydrocarbons from 27:700 phenols from 27:702,703 sterols from 27:702 tocopherols from 27:702,703 triterpenes from 27:702 volatile components of 27:700, 701 One-carbon homologation 3:238 of allylic alcohols 3:238 Onnamide 26:1231 Kishi's retrosynthesis of 26:1231 Oppenauer oxidation 13:451 ;20:749 Oppolzer-Battig synthesis 6:45,46 of (• 9(12) capnellene 6:45,46 Oppolzer's acryloyl sultams 10:138 Oppolzer's aldehyde 14:726 (+)-vincamine from 14:726 Oppolzer's chiral acryloyl sultam 19:314 Oppolzer's chiral auxiliary 11:307,308 from (+)-camphorsulfonyl chloride 11:307,308 preparation of 11:307,308 with (E)-3-chloroacryloyl chloride 11:307,308 Optical isomers 27:378 of carvone 27:378 Optically active sulfoxides 4:489-491 synthesis of 4:489-491 Organic synthesis 6:301-303 by 1,3-dithiane 6:301-303 with FAMSO 6:311-323 with MT-sulfone 6:330-340 Organoboranes 8:472,473,478 Organocopper reagents 1:626,627 addition to ~,13-unsaturated acetals and ketals 1:626,627 Organocuprate reagent 14:509 conjugated addition of 14:509 to enones 14:509 Organolithium reagents 12:411,413 2-amino alcohol by 12:411,413 to ~-alkoxydimethylhydrazones 12:411,413 nucleophilic addition of 12:411, 413
945
Organometallic addition 4:142 to N, O-protected D-allothreoninal 4:142 Organometallic reactions 4:396,398 in prenylation methods 4:396, 398 Organometallic reagents 4:328-333 nucleophilic additions of 4:328-333 Organometallic tropone derivatives 1:573 addition of Gringard reagent 1:573 addition of organolithium reagents 1:573 Organopalladium reactions 16:367 Organoselenium technology 13:5 Organosilicon compounds 13:473-518 Orthoester Claisen rearrangement 1:446,447,598 Orthometallation 14:684,686 Orthoquinodimethanes 3:434 synthesis of 3:434 Osmium (III) chloride 12:162 Osmium tetraoxide 4:169,178 hydroxylation with 4:508,509 in cis-bishydroxylation 4:160, 163 selectivity of 4:160-162,172,180 Osmylation 1:141,413,441 ;4:160,162, 175-185;6:182;13:400,401 ;16:323, 324,326,329,332;19:226-275 anti-stereoselective 4:161,162, 167,170,171,178 in synthesis of eight-carbon sugars 4:163-172 in synthesis of eleven-carbon sugars 4:188 in synthesis of nine-carbon sugars 4:180-182 in synthesis of seven-carbon sugars 4:175-179 in synthesis of ten-carbon sugars 4:192-185 Kishi's rules 1:413,414 of allylic ethers 1:413,414 of chiral allylic alcohols 4:160 of bis-allylically substituted
cyclopentenes 19:355
syn-stereoselective 19:355 Overman synthesis 13:487,488 of (+)-elaeokanine B 13:487, 488 of (+)-streptazoline 13:514,515 Oxabicycles 10:214 synthesis of 10:214 Oxahydrindene subunit of avermectins 12:9-11 Barrett's approaches for 12:9-11 Crimmins synthesis of 12:11,12 Danishefsky synthesis of 12:12, 13 Fraser-Reid synthesis of 12:13, 14 Hanessian synthesis of 12:14,15 Hirama synthesis of 12:15,16 Ireland approach for 12:15,16 Julia synthesis of 12:19,20 Jung synthesis of 12:19,20 Kozikowski approach 12:20-22 Ley synthesis of 12:25,26 Smith synthesis of 12:25,26 Vang synthesis of 12:26,27 White synthesis of 12:27,28 Williams approach for 12:28-30 Oxalacetic acid 30:433,435 reaction of 30:433 [l,2]-Oxaza ring formation by Meisenheimer rearrangement 6:472 2-Oxazolidinone 12:411,415 3-acetyl-2-oxazolone from 12:411,415 acyclic amino alcohol from 12:428-430 acyclic N-boc amino alcohols from 12:428-430 from 1,35-tris (2-hydroxyethyl) cyanuric acid 12:411,415 N-protection of 12:428-430 2-oxazolone from 12:411,415 ring opening of 12:428-430 with di-tert-butyl dicarbonate [BOC)20] 12:428-430 debenzylation of 14:569 from N-benzoylcarbamate 14:569
946
pyrrolidine derivative from 14:569 Oxazolidinone auxiliaries 18:161 2-Oxazolidinone ring 12:428-430 4-methoxy group on 12:428-430 substitution of 12:428-430 2-Oxazolidone derivatives 12:166 synthesis of 12:166 Oxazoline 10:474-477 as chiral auxiliary 4:327,332,333 of 2-acetamido-2-deoxy-Dglucose 6:399 in the synthesis of Li substances 10:473 in the synthesis lacto-N-biose 10:473 A-2-Oxazoline 4:140,141 from D-threonine 4:140,141 with furfurylithium 4:140,141 Oxazoline derivative 6:399 Oxazoline method 6:393 Oxazoline rings 4:86 synthesis of 4:86 Oxazolo [4,3-a] decahydroisoquinolines 12:464 2-Oxazolone 12:411,415 from 2-oxazolidione 12:411,415 preparation of 12:411,415 N-acetyl derivative 12:411,415 Oxepan-4-ones 10:219 bis-Oxepane 10:205 cis-Oxepane 10:211,212 Oxepane 10:202,205-207 synthesis of 10:202,205-207, 209-212,214,215,224-226 trans-Oxepane 10:211,212 synthesis of 10:211,212 Oxepanols 10:230 synthesis of 10:230 3-Oxepanols 10:231 synthesis of 10:231 Oxepanone 10:205,209 3-Oxepanones 10:209,210 Oxepins 10:236 synthesis of 10:236 Oxetanocin 10:585-627 synthesis of 10:585-627 Oxetanosin A 19:511 ,B-Oxidation 25:166
Oxidation 24:13,16,17,27,28,32,33,36, 37,80,82,94-96,104,124,178,179, 185;27:749,774 aerial 16:66 by ninhydrin 16:83 by Sharpless procedure 8:23 enantioselective 13:54 enzymatic 13:58 in vitro 6:138 in vivo 6:138 Lemieux-Johnson, 4:592,593 nitro to keto 1:417,418 of (+)-catechin 27:774 of cytochrome P450 enzymes 27:348 of terminal acetylene 27:348 of xenobiotics 27:749 of vincristine 27:778 of (-)-borneol 16:124 of (+)-5-methoxylaudanosine 16:506 of (+)-camphor 16:149,153 of (+)-laudanosine 16:506 of 1, l'-methylene bis (3,7diisopropylazulene) 14:340,341 of 1,3 dimethylazulene 14:336, 337 of 1,5-diisopropylazulene 14:337,338 of 1-isopropylazulene 14:336 of 2-ethyl-5-pentylpyrrolidine 6:444 of 2-furycarbinol 19:473 of 3,3'-methylene bis (guaiazulene) 14:343-345 of 3,3'-methylene bis (guaiazulene) 14:344 of 4,6,8-trimethylazulene 14:341,342 of alcohol 16:40,350 of alcohols to ketones 4:331 of aldehyde 16:294;19:210 of alkene 16:459 of allylic alcohol 16:296 of amides 1:10 of aromatic compounds 6:509 of azulenic hydrocarbons 14:313-354 ofbenzylic alcohol 19:225
947 of bromonaphthol 16:48 of cholesterol 17:207 of conjugated dienes 16:420 of dimethyl 2-amino- I ,3azulenedicarboxylate 14:339 of di-substituted azulenes 14:336,337 of ellipticine 6509 of enol acetate 19:207 of enol ether 16:85 of enolate 16:474 of FAMSO 6326 of formaldehyde dimethyldithioacetal 6326 of friedelin 7: 160,I6 1 of genipin 16:3 13 of guaiazulene 1 4 3 13-3.54 of hemiacetal 1:4.53,454 of h y d r a d e 16:473 of lactol 19:473 of oleanane triterpenoids 7: 159-I61 of olefin 10: 1 1 1 of olefins to ketones 4:333 of phenolate 19:233 of phenylsulfide 16:296 of phosphite linkage 4:280 of phosphonate linkage 4:280 of phosphonium ylides 4558, 559 of secondary hydroxyl group 19:489 of sulfide to sulfone 1:4.54,4.56 of taraxerone 7: 160,16I of tertiary allylic alcohol 19:262 of tetrahydroisoquinolinols 16:s I9 of tetra-substituted azulenes 14:343-34.5 of tri-substituted azulenes 14339-342 of unactivated carbons 2:90-103 of cqp-unsaturated ketones 4: 100 Pd (11)catalysed 4: I00 photochemical 1: 159 regioselective 19:262 Swern 1:453,454 using Kelly procedure 10:1 1 1 with AczO-AcOH 8:160,162
with Attenburrow-Mn04 8:1 19 with benzeneselenic anhydride 4:40,4 132 with ceric ammonium nitrate 43.3 1,332;6:472 with ceric sulphate 1: 159 with Collin's reagent 1:360,363, 367 with DDQ 8: 169;19:473 with H&aq. NaOH, 8: 163 with HgO/12 1:4.54,4.56 with iodine 1: 126,I38 with Jones reagent 19:I36 with KMn0,-NaOtBu 1:417 with m CPBA 2:90-103 with manganic acetate 4:72 with mCPBA 19:71 with MnOz 8: 198;16:294 with N(n-Prop)4 RuO, 8: I SO-152 with o-chloranil 1:13I , 132,135, I37 with osmium tetraoxide 10: I I I with Os04 8:23;16:292 with oxone (KHS05) 1:454,456 with palladium 1: 13I , 133 with Pb ( OAC) ~ 8: 165 with PCC 19:62,473,.541 with PDC 19: 145,265 with Ph I (OCOCF& 4:73 with PPC 1:440 with pyridinium chlorochromate (PCC) 8:22,23,163;11:401 with pyridinium chlorochromate 1:208;6:1 I7 with pyridinium dichromate 4331 with RuOl 1:404,40.5;8:150- 1.52 with Ru04-NaI04 8: I62 with SeOz/t-BuOOH 8:2,3 with silver carbonate 1:453,454 with silver oxide 11:86 with sodium chlorite 1693 with sodium metaperiodate 4:50;19:354 with sodium periodate 16:293 with Swern oxidant 6:1 19,120 with tetrapropylammonium metaperiodate 1:3793 80 with thallium acetate 4:72
948
with thallium nitrate 4:338; 8:166,167,169 Oxidation-Wittig homologation 13:612, 613 stereospecific 9:255,256 Oxidative burst 27:65,66 Oxidative cleavage 30:8 of p-methoxybenzyl (PMB) ether 30:8 Oxidative conversion 19:484 Oxidative coupling reaction 8:160 olefin 8:160 of phenol 8:160 Oxidative cyclization 9:533 of davanones 9:533 Oxidative decarboxylation 1:536 of c~-keto acids 1:536 Oxidative degradation 13:303-306 of fatty acids 13:303-306 of ilimaquinone 9:31 Oxidative demethylation 5:769 Oxidative elimination 3:260 of arylselenide 3:260 Oxidative halogenation 27:750 and electron transfer 27:750 Oxidative hydroboration 12:318,322, 344;14:460,461 Oxidative hydrolysis 30:438 formation of 30:438 of dithioacetal moiety 30:438 of KDO derivative 30:438 Oxidative Nefconditions 19:73 Oxidative olefination 4:448 Oxidative phenolic coupling 20:291-293 in biosynthesis of 20:291-293 natural products by 20:263-315 Oxidative rearrangement 16:650 Oxidative transformations 7:159-168 Oxidative-degradation system 7:105 Oxidising action 2:3 of NO in CI (NO) mass spectra 2:3 Oxidizing agents 19:120 Oxidizing enzymes 6:520 in Strychnos dinklagei 6:520 Oxidopyridinium ions 1:340 1,3-dipolar cycloadditions of 1:340
Oxirane opening 1:560,561 influence of cz-OH 1:560,561 reaction with lithiated nucleophile 1:157 regiospecifity of 1:560,561 with dilithioacetate 1:558,560, 561 Oxirane ring opening 30:463 Oxirans 12:411,413 2-amino alcohol by 12:411,413 ring opening of 12:411,413 with nitrogen nucleophiles 12:465 Oxo reaction 3:223,4:255 13-Oxo-9,11-octadecadienoic acid 27:73 generation of 27:73 13-Oxo-9-hydroxy- 10-octadecenoic acid 27:73 generation of 27:73 Oxocarbenium ion 16:94,95,108 formation of 16:94 Oxocene 10:204 oxidation of 10:204 synthesis of 10:203,204,211, 218,224,225 unsaturated 10:231 Oxocenones 10:217 synthesis from ~5-1actones 10:217 Oxyallyl zwitterion 14:587 Oxyaminations 12:411,413 2-amino alcohol by 12:411,413 of alkenes 12:411,413 Oxy-Cope rearrangnement 3:96;6:28, 29,36,538-540;7:216;8:179,234,246, 249;10:61,416;11:43,45-49,627; 18:17 anion assisted 16:459 anionic 4:591;16:127,127;19:6 in the synthesis of macrocycles 8:245 of tertiary alkoxide 16:127 suprafacial 16:12 Oxy-functionalization 27:749 of aromatic amines 27:749 of phenols 27:749 Oxygenated monoterpenoids 27:373
949
Oxygen-containing heterocycles 10:220,221 by cyclization of mixed acetals 10:220,221 from Lewis acid catalyzed reaction 10:220,221 Oxymercuration 10:67,185,324 Oxymercuration cyclization 1:423,425 Oxymercuration-demercuration procedure 14:538,539 Ozonation 26:355 Ozone-triphenylphosphine adduct 4:554 oxidation of ylides with 4:558, 559 Ozonization 1:264,265 of olefin 1:439 of (+)-dihydrolimonene 6:541 Ozonization reaction 14:416,417 with thujone 14:416,417 Ozonolysis 4:523;5:590;6:137,298,299; 8:139;9:338,359,525,527;11:337, 338,369;12:81 ;14:101 ;16:495,649, 712;20:409;21:417,432,712,714,715; 26:81,86;30:486,489 in steroid moiety synthesis 30:486 of ergosterol 30:489 cardanol methylether by 9:338 of alkene 16:462 of diacetate 5:599 of diacetylirumamycin 5:599 of enol ether 16:495 of enyne 16:384 of ergosterol 16:336 of olefins 10:565 of seleno ether 16:7 of stigmasterol 16:324,336 of streptolydigin 14:101 reductive 4:523 Ozonolytic cleavage 13:258,604 of (+)-A3-carene 16:258 Ozonolytic degradation 6:137 of 19'-hexanoylfucoxanthin 6:137 of peridinin 6:137 Pal and Mukerjee 29:180 pisiferic acid synthesis by 29:180
Palladium (0) 3:82,83 for macrocyclization 3:82,83 Palladium (0) catalyzed cyclization 8:228 of allylic acetates 8:228 Palladium (O)-catalyzed condensation 12:300 Palladium (O)-catalyzed coupling 21:381 Palladium (II) acetate 10:344 Palladium acetate 1:19 coupling with 1:19 Palladium black 14:763 as catalyst 14:763 Palladium catalysed acetalization 1:584 Palladium catalysed coupling 3:258 with [PdC12(PPh3)-Cu I)] 1:532 Palladium catalyzed rearrangement 14:625 Palladium coupling reaction 30:12 Palladium dehydrogenation 1:129,130 Palladium mediated coupling 10:341 regiospecificity of 10:341 stereochemistry of 10:342 stereospecificity of 10:341 Palladium mediated oxidation 12:241 Palladium-catalyzed biaryl coupling 29:407 rhazinilam synthesis by 29:407 Palladium-catalyzed coupling reaction 30:8 of vinyl iodide 30:8 Palladium-catalyzed cross-coupling reaction 30:17 Palladium-catalyzed cross-coupling 21:392 Palladium-induced indolizidine ring formation 12:299 Palladium-promoted reaction 16:367 of vinylic bromide 16:367 Palomo's reagent 21:428,442 Panek's synthesis 26:1224,1225 of dipeptide 26:1224 of ]3-methylaspartate 26:1225 Paraherquamide A 28:331,367 asymmetric synthesis of 28:367 conversion of PHB to 28:335
950
hydroxylation of MFA 28:335 total synthesis of 28:367 (+)-Paraherquamide B 28:359 conversion of MFA to 28:333 stereocontrolled synthesis of 28:358 Paraherquamides 28:331,332 synthesis of 28:332 Parikh oxidation 12:305 Parikh-Doering oxidation 14:60 Park and Danishefsky 29:486 valienamines synthesis by 29:486 Parsons approach 12:24 for hexahydrobenzofuran component 12:24 of avermectins 12:24 Partial synthesis 6:157-160 of acetylenic carotenoids 6:157-160 of anguidine 6:225,226 of carotenoid sulfates 6:150 of gibberellins 6:186-194 Passerini reaction 12:131,138 Pateamine 28:709 total synthesis of 28:709 Paterno-Buchi photocycloaddition 10:440 Paterson's synthesis 26:1229;30:22-26 of discodermolide 30:22-26 of swinholide A 26:1229 of iso-swinholide A 26:1229 Pattende's synthesis 12:180,181 of verticillene 12:180,181 Paulsen method 6:357 Pauly's reagent 17:396 Pauson-Khand cyclization 3:83,84 Payne rearrangement 4:173,179,186, 344;11:10,36,38;12:209 PCC Oxidation 6:545 Pd(O)-catalyzed carbonylation 10:29 PDC oxidation 16:23 Pd-catalyzed cross coupling reactions 10:1161-163 Pellegata oxidation 19:226 Peniophora sanguinea 29:298 biosynthesis in 29:298 5-Pentadecenal 26:75 wittig reaction of 26:75
3-Pentanone 30:l0 aldol condensation of 30:10 N~,N4,N7 ' N lo, N l s_Pen ta_ -coumaroylspermidine (coumaroyl amide) 29:573 synthesis N~,NS, Nt~ - coumaroyls of permidine 29:573 Pentasaccharides 10:475,476 by glycosylation 10:475,476 synthesis of 10:475,476 Pentenylation 12:466 Peracid oxidation 14:320-324 of guaiazulene 14:320-324 Perhydrogenation 6:149 of (3R,3R')-zeaxanthin 6:149 Peri interaction 1:386 [2cy+2cy+2~]-Pericyclic reaction 16:621 [2~+2cy+2~]-Pericyclic reaction 16:628 Pericyclic reactions 3:418 of arynes 3:418 Periodate 2:346 oxidation of glucoamylase 2:346 Periodate-nitromethane procedure 4:240 for purine synthesis 4:240 trans-anti-Periplanar fashion 11:301, 302 Perkin condensation 12:381 intramolecular 12:381 Permethylation 5:199 Permethyl-O-rhamnose moiety 27:879 Peroxidase-catalyzed dimerization 27:765 of p-coumaryl-hydroxy oxyagmatine 27:765 of p-coumaryl-hydroxyagmatine 27:765 Peroxidase-catalyzed reactions kinetics 27:741 Peroxidase-mediated oxidation 27:777 of (+)-catechin 27:777 Peroxidases 27:735,755 for synthesis of natural bioactive alkaloids 27:778 in synthesis bioactive alkaloids 27:788 in synthesis of bioactive plant phenols 27:755
951 Peroxidized oil-treated group 27:408 Peterson olefination 3:202;8:247,248; 11:10,11 ;19:374 in 13-dictyopterol synthesis 6:19,189 Phaseic acid 27:346,350 formation of 27:346 isomerization rates of 27:350 Phenanthrene ring enlargement 29:374 in allocolchicinoids total synthesis 29:374 Phenolic coupling reactions 16:504 Phenolic lipids 30:111,139,150-176 synthesis of 30:139-150 Phenolic o~-diazoketone 6:60,61 bromochammigrene from 6:60, 61 spiroannulation of 6:60,61 Phenols 17:586;27:702,703 anodic oxidation of 8:159-172 chemoselective protection of 19:304 chromanes from 4:394 oxidation with TI (03)3 (TTN) 8:166,169 from olive oil 27:703 oxy-functionalization of 27:749 photosenstized oxygenation of 16:582 Phensulfinylation 19:470 ~-Phenyl selenide 6:16 in 13-dictyopterol precursor synthesis 6:16 Phenyl sulfone derivative 30:486 dehydration of 30:486 hydrogenation of 30:486 synthesis of 30:486 vic-Phenyl thiobenzoate 6:541-542 metal reduction of 6:541-542 1-Phenyl-2-buten- 1-one 3:129 reaction with silyl enol ether 3:129 Phenylacetaldehyde 6:312 synthesis of 6:312 Phenylacetic acid derivatives 6:320-322 synthesis of 6:320-322
Phenylation 19:497 of aldehyde 19:497 chemoselective 19:497 3-Phenylcyclohexanone 12:25 sulfenylation of 12:25 Phenylethanal 30:215 reaction of 30:215 2-Phenylnaphthalene 30:214 C-condensation of 30:214 from arylethanals 30:214 mechanism of formation of 30:214 Phenylpropanoid moieties 27:853 Phenyl-pyrrole analogues 29:406 rhazinilam synthesis of 29:406 Phenylselenyl bromide 14:737 in quinolizidine formation 14:737 Phenylselenyl chloride 6:426-428 cyclofunctionalization with 6:426-428 Phenylselenylation 1:242,248 Phenylserine 30:216 conversion of 30:216 Phenylsulfone derivatives 30:488 synthesis of 30:488 1-(Phenylsulfonyl) indole 6:509,510 regiospecific lithiation of 6:509, 510 ~z-Phenyl-y-lactone derivative 10:410, 411 alkylation of 10:410,411 stereoselective 10:410,411 Phosgene 12:113 isocyanides from 12:113 Phosphate 27:872 hydrolysis of 27:872 Phosphite method 4:271-274,280 for oligonucleotide synthesis 4:271-274,280 in oligoribonucleotide synthesis 4:303 mechanism of 4:272 oxidation reaction 4:280 Phosphitylating agents 4:272,273; 13:276 Phosphitylation 8:388,389 Phosphoenolpyruvate 30:423 synthesis of 30:423
952
Phosphonate condensation 19:83 Phosphoniosilylation 3:79,80 of enones 3:79,80 Phosphonium mercaptides 4:554 Phosphonium ylides 4:553-578 acylation with thioesters 4:554 acylation with trimethylsily esters 4:564 oxidation 4:553,558 Phosphoramidite 4:306 in coupling reactions 4:306 Phosphoramidite method 13:270 methylphosphonates by 13:270 Phosphoramidites 8:373;13:265,267, 268,269,270;18:398 synthesis of 8:388-390 Phosphorodichloridate 8:83 Phosphorodithioates 13:268,269,270, 271,274 from thiophosphoramidites 13:272,273 Phosphoroimidazolidate 8:90 Phosphorothioates 13:263,268,269 diastereoselective synthesis of 13:276 Phosphorus oxychloride 8:72,73 with diisopropylamine 12:113 Phosphorylation 8:97,100;9:391; 12:384;18:395,397-402 ;30:808 dihydrogen phosphate 8:105 methylphosphonates by 13:272 of alcohols 8:80 of citronellol 8:76 of E-geraniol 8:76 of G-coupled proteins 30:808 of mevalonic acid 7:322 of prenols 8:75,80 Phosphotriester method 4:268-271, 301-303 ;13:271,272 for oligodeoxyribonucleotides synthesis 4:268-271,301-303 in oligoribonucleotide synthesis 4:301-303 methylphosphonates by 13:272 reaction mechanism 4:270 using polymer support 4:271 Phosphotriesters 13:263,271 synthesis of 13:272 Photoaddition 3:102,103 ;24:201
Photoautotrophic cell lines 7:9 N-phthalylaspartic acid 7:10 Photochemical 6:331,333 hydrolysis 6:331,333 Photochemical [2+2] cycloaddition 1:548 Photochemical acyl migration 1:51 Photochemical annulation 6:48 in (+)-A9~12~-capnellenesynthesis 6:48 of 13-diketone 6:48 Photochemical decarboxylation 3:487 of allylic carboxyls 3:487 Photochemical olefin isomerization 1:413,414 Photochemical oxidation 1:159 Photochemical reaction 6:330,331 Photochemical rearrangement 1:547; 14:356-360 Photochemical synthesis 20:302,303 Photochemical transformation 1:218, 219 of protoberberine 1:218,219 of spirobenzylisoquinoline 1:218,219 Photochemical valence isomerization 1:189 Photocyclization 1:45,52,63,141; 3:14-17,19,"3,309,414;14:65;16:32; 24:759,760 of oxopropyl ester 8:131 of phenacyl ester 8:133 non-oxidative 3:403-406 of enamides 3:401-403 reductive 3:402,407,407-410,414 Photocycloaddition 11:20;16:651 [2+2]-Photocycloaddition 3:97;6:39; 8:251 ;10:405,406;16:264 diastereoselective 14:502 of cyclic enones 14:502 with chiral ~,]3-unsaturated acetals 14:502 [6rt+2rt]Photocycloadditions intramolecular 1:568,569 of alkenyltropones 1:568,569 Photodeoxygenation 3:199 Photodiode array detection 9:462 Photo-Fries rearrangement 499
953
Photo-induced annulation 12:293 of N-alkylated pyrrolidinones 12:293 Photo-induced deoxygenation process 14:166 Photoinduced electron transfer 30:540 in [3-carotene 30:540 in canthaxanthin 30:540 Photo-induced electron-transfer 14:166 Photo-induced reduction 14:166,167 of esters 14:166,167 Photo-initiated radical allylation 12:487 Photoisomerization 12:236 of 3-oxo-4,5-oxido steroids 12:236 of ABA 27:354 cis, trans-Photoisomerization 27:355 Photolactone 8:134 Photolithography 13:646 Photolysis 6:475,476 of (_+)-laudanosine methiodide 6:475,476 of (-)-orientalinone 16:512 of (4-oxopentyl)D-glycoside 10:420 of carbohydrate derivatives 14:649,650 of enamine 16:469 of N-alkenylbenzotriazoles 13:445,446 of nitrone 6:474,477 of phthalimide derivatives 14:649,650 of trans-canadine N-oxide 6:474 of [3-ketoester 14:652 Photo-oxidation 6:472,491,492;16:604; 30:443 role in aldol reaction 30:443 Photo-oxygenation 1:190,214; 4:419-421,424;14:597,601 of coptisine 1:191 of palmatine 1:191 of protoberberine 1:203 Photophosporylation 21:98 Photorearrangement 16:512 Photoreduction 1:257 intramolecular 1:257 Photosensitized oxidation 6:138,142
Photosolvolysis 6:475,476 of 2,5-benzoxazonine 6:475,476 ring destruction by 6:475,476 Photosolvolytic reactions 6:472,475, 477,484 Photosynthesis 30:521,762 Physarum polycephalum 29:239 synthetic derivatives of 246 Phytoalexin synthesis 25:507 Phytolysis 27:330 of bovine serum albumin 27:330 Pictet-Spengler condensation 1:72; 14:633 Pictet-Spengler cyclization 8:265,266, 288,289;19:301 ;30:216 Pictet-Spengler reaction 1:139,140; 4:13,16,17,23;10:87;13:408-410; 14:633,759,761,763 (+)-endo-6-bromocamphor from 4:644 Pictet-Spengler type reaction 19:91 of tryptamines 19:91 Piers annulation 6:21,22 of methylene cyclophexane 6:21,22 Piers synthesis 6:22 of palauolide 6:22 Pig liver esterase (PLE) 13:56 asymmetric hydrolysis with 1:685 Pinacol coupling 18:443 Pinacol rearrangement 11:52-54; 14:360-362; 15:500;18:174;19:397 of hydronaphthalene- 1,10-diol monosulfonate esters 14:356 of 913-hydroxy-11-oxoderivative 19:399 Pinacol rearrangement 24:785,786 of arboreol 24:785,786 Pinacol-pinacolone rearrangement 16:127 of diol 16:127 Pinacol-type derivatives 8:4 Pinner reaction 5:557,558,561,566,574 Pinoresinol 27:760 polymerization of 27:760 Piper amides 24:683-783 synthesis of 24:717-733
954
3-Piperidinol alkaloids synthesis 29:419 by stereodivergent process 29:419 Pirkle reagent 9:241 Pironetin 30:3,26-46 biosynthesis of 30:26,29 Chida's synthesis of 30:38-40 Dias synthesis of 30:44-46 Gurjar's syntheses of 30:33-37 Kawada's synthesis of 30:30-33 Keck's synthesis of 30:42-44 Kitahara's synthesis of 30:40-42 synthetic routes to 30:3,30 Pisiferic acid synthesis 29:173 by Banerjee 29:174 by Geiwiz and Hasslinger 29:185 by Mori and Mori 29:182 by Pal and Mukerjee 29:180 enone cyclization in 29:173 from abietic acid 29:188 ketones preparation in 29:174 starting materials for 29:177 transannular oxidation in 29:173, 174 yield in 29:174 Pivaloyl group 6:292,293 protection with 6:264,268,276, 282,283 Pivaloylation 13:32 Podolactones 28:495 synthesis of 28:495 Podophyllotoxin 24:740 synthesis of 24:740 (-)-Podophyllotoxin 24:767 from endo addition 24:767 synthesis of 24:767 Polonovski reaction 1:105-110,112; 14:715-746,811,815,816,857,858, 869-872 modified 4:31 Polonovski-Potier-Husson reaction 1:79,80 Polonvski-Potier reaction 1:49 Polycarpamine A 28:640 synthesis of 28:640 Polycarpamine B 28:640 synthesis of 28:640
Polycarpamine C 28:640 synthesis of 28:640 Polycondensation 7:458 Polycycles 8:278 synthesis of 8:278 Polycyclic amine alkaloids 24:573-672 synthesis of 24:613-617 Polycyclic arenes 11:113 functionalization of 11:113 Polycyclic aromatic compounds 7:8-10 polyfunctionalized 11:113 synthesis of 11:119-127 via aromatic 13,13,&&tetraoxoalkanedioates 11:119-127 Polyene acetal 14:471 tetracyclization of 14:471 Polyene cyclization 8:188 acid catalyzed 8:188 biomimetic 14:740 initiators 1:656 steroids from 14:740 Polyene synthesis 20:571 Polyhydroxy-p-terphenyl 29:295-297 biosynthesis of 29:295-297 Polyhydroxy-p-terphenyl s 29:298 synthesis of 29:298 Polyhydroxyterphenyls 29:300 synthesis of 29:300 Polymer support synthesis 4:274, 277-283 protecting groups 4:276 protocol for oligonucleotide synthesis 4:288 Polymer supports 3:82,83 for macrocyclization 3:82,83 Polymerization 27:760 of dihydrodiconiferyl alcohol 27:760 of guaiacylglycerol-[3- Oconiferyl alcohol 27:760 of cinnamyl alcohols 27:760 of coniferyl alcohol 27:760 ofp-coumaryl alcohol 27:760 of sinapyl alcohol 27:760 of pinoresinol 27:760 Polyphenylalanine synthesis 7:386 Polyphosphoric acid cyclization 1:58 Polyphosphoric acid trimethyl silyl ester (PPSE) 12:377
955
Polyporic acid 29:298 synthesis of 29:298 Polyprenyl diphosphate sugars 8:63,64, 68-106 deacetylation of 8:88 from phosphorobenzimidazolidate 8:90 from phosphoroimidazolidates 8:89,107,108 synthesis of 8:68-70,86-92 Polyprenyl monophosphate sugars 8:82 from glycosylcation 8:82 from glycosyl-oxyanion 8:83 from phosphoroamidates 8:80, 81,107 synthesis of 8:68,69,82-86 synthesis with prenyl cation 8:69 synthesis with prenyl halides 8:69 synthesis with tosylates 8:69 Polyprenyl phosphates 8:70,71 from prenyl trichloroacetimidates 8:70,71 synthesis of 8:68-72 Polypropionates 17:25,26;18:155 Pomeranz-Fritsch isoquinoline synthesis 129 Pomeranz-Fritsch reaction 16:510 Ponaras reagent 13:16 Pondorf-Meerwein-Verley method 17:605 Positional isomers 29:378 allocolchicinoids total synthesis of 29:378 Potassium ferricyanide 22:204,211 Potassium graphite (CsK) 11:366,367 Potassium tri (seco-butyl) borohydride 1:261 Potier's synthesis 14:869-873 of vinblastine 14:869-873 Prelog-Djerassi lactone 3:225-257; 10:423 synthesis of 3:227,255-257; 16:711 Prelog-Djerassi lactonic acid 14:267 synthesis of 14:267 Prenylation methods 4:367-402 by alkali metals 4:386-400 by chromanes 4:394-396
by Friedel-Crafts alkylations 4:391,394 by organometallic reactions 4:396,398 by silver oxide method 4:386 by trimethylsilyl intermediates 4:394 in basic media 4:386-391 of 2,6-dihydroxy-4-methoxyacetophenone 4:386,387 of 1,3-dimethoxybenzene 4:89 Prenyl-naphthoquinone lapacholsynthesis 29:719 from lawsone 29:719 Preparation 23:57,60,84 ofrifamycin S 23:57,60,84 Previtamin D derivatives 30:486 thermal isomerization of 30:486 cis-Principle 4:584,585 in Diels-Alder reactions 4:584, 585 Prins cyclization 18:174 Prins reaction 13:41,42;18:882,891 Probes 27:332 for 7',7'-difluoro-ABA 27:348 for 7'-hydroxylation 27:348 for 8'-hydroxylation 27:346 for isomerization to phaseic acid 27:348 Prochiral carbonyl groups 4:332,333 asymmetric addition to 4:332, 333 Prochiral ketones 1:689 chiral alchohols from 1:689 reduction with yeast 1:689 Prochiral naphthalene rings 4:332 asymmetric additions to 4:332 Prochiral sulfides 14:517,518 asymmetric oxidation 14:517, 518 Prolines 4:327 as chiral auxiliaries 4:327 /-Prolinol 14:743-747 as chiral auxiliary 14:743-747 Prolycopene 7:330-335 Propane- 1,3-diols 13:53-105 asymmetric synthesis of 13:53-105 enantioselective 13:53-55
956
enzymatic 13:55 transesterification of 13:53-55 (S)-Propargyl alcohol 13:585 Propargyl alcohol 14:569 cis-olefin from 14:569 pyrrolidine derivative from 14:569,570 Propargylic alcohols 14:473 synthesis of 14:473 Propargylic titanium reagent 12:24 from alkyne 12:24 with methacrolein 12:24 Yamamoto condensation of 12:24 Propranol 27:394 from glucose 27:394 Prosafrinine synthesis 29:419 by stereodivergent process 29:419 Prosafrinine/iso-6-cassine synthesis 29:425 of ~,~'-Disubstituted 3piperidinol alkaloids 29:425 Prosophylline synthesis 29:419 by stereodivergent process 29:419 Prosopinine synthesis 29:419 by stereodivergent process 29:419 Protecting groups 4:299 acid labile 4:299 anilido 4:286 base labile 4:299 benzyl 4:299 2'-O-t-butyldimethylsilyl (TBDMS) 4:299 1-[(2-chloro-4-methyl) phenyl]4-methoxy-piperidin-4-yl (CTMP) 4:299 5-chloro-8-quinolyl 4:286 2-cyano-l,l-dimethylethyl 4:285 2-cyanoethyl group 4:285 dimethoxytrityloxyethyl sulfonyl ethyl 4:285 for 2'-hydroxyl 4:296 for 5'-hydroxyl 4:297 for internucleotidic phosphate group 4:268 for phosphomonoester formation
4:285 in polymer support synthesis 4:276 p-methoxybenzyl (MBn)) 4:300 3-methoxy- 1,5-dicarbomethoxypentanyl (MDMP) 4:300 methoxytetrahydropyranyl 4:297 (1 -methyl- 1-methoxy) ethyl (MME) 4:300 monomethoxytrityloxyethylamino 4:289 o-nitrobenzyl (NB) 4:300,301 p-nitrophenylethyl 4:285 ent-pseudoguaianolide intermediate 4:675 2-(2-pyridyl) ethyl 4:286 tetrahydrofuranyl 4:297 tetrahydropyranyl 4:297 trihaloalkyl 4:285 3,4,5-trimethoxybenzoyl 4:299 Protection 6:284,285 with cyclocarbonate group 6:284,285 with lauryl chloride 6:429 with MEM 6:558,559 with methoxyethoxy group 6:298,299 with methoxymethyl group 6:282,283 with O-isopropylidene 6:269,270 with pivaloyl ester 6:264,268 with propanedithiol 6:300,301 with tert-butyldimethyl silyl ether 6:264,268 with tetrahydropyranyl ether 6:264,268 Protection of alcohol 1:440,442,443 with tert-Bu Me2SiOCH2COC1, 1:440,442,443 Protection of inositols 18:403-421 Protection/deoxygenation procedures regioselective 14:744 Protein biosynthesis 21:97,98 Prototropic cyclization 25:141 Pschorr reaction 20:301 ;16:504 Pschorr-type diazo-couplings 20:301,302 Pseudolaric acid B 21:754-759 synthesis of 21:757
957
Pseudopterosins 23:154,158,180 synthesis of 23:154,158,180 Pummerer intermediate 3:461 ;14:646 Pummerer reaction 1:63-65;4:139,464; 10:678,682;11:326,327;14:539-546, 747;19:14 Pummerer rearrangement 4:36-39,496, 505,506,510;6:317-319,321,328,335; 12:160,161,324;14:539;16:230,671 Pyranoid carbasugars synthesis 29:466 by Duhram 29:466 by Furuta 29:466 by McCasland 29:466 Pyridinium acetate 11:84,85 lactonization with 11:84,85 Pyridinium chlorochromate 7:478; 11:93,94;12:492 oxidation with 4:117,118;6:116, 118 Pyridinium methylides 1:334,335 cycloaddition with 1:334,335 Pyridinium salts 1:91 reduction with dithionite 1:91 Pyrolysis 14:268;17:455 levoglucosenone from 14:268 of isoquinoline N-oxide 6:468 of N-acyllactams 6:430,431 of N-lauryl-6-methyl-2piperidone 6:430,431 of acid-treated cellulose 14:268 of protopine N-oxide 6:494 of microgranular cellulose 14:268 Quassinoid derivatives 23:303 preparation of 23:303 Quaternary carbon 8:3-14;14:631-644 asymmetric 10:405-412, 426-428 asymmetric induction of 10:412 chiral construction of 4:4-27; 14:631-644 synthesis of 8:3-14 through addition elimination process 14:631-644 Quaternization 6:513,514 by 4-nitrobenzyl bromide 6:513, 514 Quinone-Diels-Alder adducts 16:548
Quinonemethides 30:666 biosynthetic pathway of 30:666 Quinones 30:304,682 biosynthesis of 30:682 Quinone-styrene reaction 16:547, 551-552,559,560,564,565 Lewis-acid promoted 16:565 Racemic acerolide 23:176 synthesis of 23:176 Radical chemistry 16:30 Radical coupling reactions 11:464,465 Radical cyclization 1:256-258,292; 24:15-18 of haloolefins 3:13 of phenylselenyl derivative 3:462 of tertiary alcohol 16:235 stereoselective 19:54 thermal 16:41 tin mediated 1:483,490 with R3 SnH 3:38 Radical induced deoxygenations 14:157-162 of carbohydrates 14:157-162 Radical mechanism 14:166 Radical Michael addition 12:281 Radical olefin cyclization 3:327 Radical oxidation 27:346 Radical polymerization 6:541,542 Radical reduction 11:141 2-deoxy- 1-hydroxysugars from 11:141 of dithiocarbonates 3:475 Radical spirocyclization 16:28,33,35, 41,51,53,63 thermal 16:55 Radical-alkene cyclization 3:327,328 Radical-cation coupling 24:776,777 Ramberg-Backlund olefination 18:205, 206 Ramberg-Backlund reaction 8:208 Ramberg-Backlund rearrangement 24:12,13 Random Bi-Bi process 11:201 Raney nickel 6:150,151;14:736,828 desulfurization 11:357
958
catalytic hydrogenation with 6:425 Raphael 29:382 steganes synthesis by 29:382 Rapoport 29:374 allocolchicinoids total synthesis by 29:374 Ras oncogene 24:403 Ras protein 24:403-464 farnesylation of the carboxy terminal cystein residue of 24:403-464 post-translation modification of 24:403-404 Rassu 29:453,483,489 carbafuranose synthesis by 29:453 dibromide synthesis by 29:483 thiocarbapyranoses synthesis by 29:488 Reaction mechanism 14:561,562 of asymmetric intramolecular Michael reaction 14:561,562 Reactivity 27:740 of enzyme intermediates 27:740 Read and Vining 29:295 biosynthesis by 29:295 Rearranged quinone-methide 5:744,745 [3,3]-Rearrangement 10:236 1,2-Rearrangement 10:412 of 13,7-epoxy alcohols 10:412 Rearrangement 3:342,355-387,467,480; 10:233-236;24:204,292-293 of homohrringtonine skeleton 24:292 in C-glucoside synthesis 3:225-228 intramolecular 3:226-228 of substituted hydronaphthalene 14:355-387 of [4.3.1]-bicyclodecanes 14:355 anionic 3:467 of sulfonyl group 6:342 of l-benzyl tetrahydroisoquinoline system 6:480 reductive 3:227 Rearrangement of camphor 4:626,627 2,6-hydride shifts in 4:626,627
2,3-exo-methyl shifts in 4:626, 627,633,634 1,2-Rearrangement reaction 10:592, 593 from pyranosides 10:592,593 pinacol type 10:592,593 Red-A1 19:482 reduction with 6:289,290 Reducing agents 19:120 Reduction 1:10,28-30,33,131,155-159, 165,166,315,316,386,592-595, 698-701 ;3:253,237,339-345,358, 590,660,718;6:115,116,119,124,126, 129,229,285,286,288,289,292,295, 296,298,299,428,426,509,511-515; 8:6,7,19,23,34,81-84,87,91-93, 98-100,103-106,162,163,165,181, 322,323,388,288;11:364-366; 12:19,45,151,152,281,283,287,290, 297,300,301,411,414;13:54,58,72, 499-502;16:155,294,295,301,307, 348;24:8,13,16,17,20,30-32,60-63, 65,66,68,72,73,85,94,103,110,111, 124,175,182,188,190,206,207; 27:830 2-amino alcohol by 12:411,414 acetal/ketal cleavage by 1:591-595 asymmetric 4:339-345 baker's yeast 19:129 by Ueno method 10:322,323 catalytic 19:475 chelation controlled 3:253 chemoselective 16:307;19:299, 329 diastereoselective 1:591-595; 14:499-502;19:334 during FAB mass spectra 2:28-30,33,35 enantioselective 13:54 enzymatic 13:58 H-H-C-Relayed 13C-1H correlation spectrum 2:101 intramolecular 12:283;16:420 1-selectride 11:365,366 of (+)-2-oxoindolizine 12:284 of (-)-camphorquinone 4:660 of 17-oxoellipticine 6:509,511 of 1-piperideines 6:426
959
of 2-enals 20:83 1-839 of 2-enoates 20:824 of 2-methylseleno-2-phenyI-6heptene 8:7 of 2-0x0 carboxylates 20:840-842 of 3-ketotrichothccene 6:229 of 7-oxoindolizidine 12:286,287 of 8-azido- 1 -p-menthenc 11:288 of ally1 alcohol 20:83 1-839 of allylic alcohol 16:348 of amide 19: 145 of azide 16: I9 of carbonyl group 19:226,229 of C-C double bond 20324 of conjugated double bond 16:155 of C-Se bond 8:7 ol' cuparenones 8:6 of cyclic P-keto esters 1597-701 of cyclopropane carbonitrile 12:287 of diterpenes 27:830 o f enamines 1:386 of exocyclic double bond 1 9 5 3 of exo-methylene-y-lactone carbonyl 1:3 I 5,3 16 o f farnesal 8: I9 of fumaratcs 20:83 1-839 of halide 11:364 of imines 6426,428 of indolimmycin 12301 of isoxazolidine 12:290 of keto group 16:348 of keto lactone 16:301 of ketones 1: I 3 1 of kingiside-agl ycone-O-sil yl ether 16:307 of lactonc to lactol 1:3 I 5,316 of N-P-oxy-I 7-oxoellipticine 651 I of primary mesylate 16:19 of symmetrical diketones 19: I29 of Tic& (DME) 8: 19 of titanium trichloride 11:364 of a$-acetylenic ketones 13:72 of a-amino ketones 12:4 1 I ,4 14 of a-halo ketones 19:193
regiowlective 6:288,289;16: 135 selective 19:1 19,228 stereoselective 11:9l;12:ISl, 152;19:259,473-474,476 stereospecific 11:98 thr-eo-selective of 12300 under Luche conditions 12:297;19:357 with (S)-Alpine-hydride 19:158 with Baker's yeast 12:28 1 with BH3-Me2S 12:28 I with Bu2AIH 8:163 with Bu3SnCI-NaBH4 1:s12 with DIBAH 6:426 with DIBAL 6:285,286;8: 165; 16:295 with diisobutyl aluminium hydride 1:315,326;4:589,590; 6:l 15,l 16;11:105,106 with Et,SiH/BF3 10:388 with hydruine 1:I3 1 with K-selectride 12: I5 I , 152 with LAH 19:475 with LiAIH, 8:23,162,163,181 with lithium aluminum hydride 11:364 with lithium triethylborohydride 11:83,84 with L-Selectride 6298,299; 19: 147 with NaBHICN 8 : 162 with NaBH, 16:348 with NaBH,/MoO, 4:237 with NaBHJNiCI? 4:237 with NaCNBHi 1:386 with NiC13-NaBH43:165,253 with PhlP 12:28 1 with Rancy Ni 16:294 with REDAL 6:288,289 with Selectride 8:I8 I with sodium borohydride 19:296 with sodium cyanoborohydridc 11:87 with sodium dithionite 16:45 with sodium hydrotelluride 11:81,82,92,93 with TiCll 1:591-595 with trialkyl aluminium 6426 with tributyl tin hydride 4:718
960 with tri-N-butyltin hydride 8:34 with yeast 1:697-701 with zinc/copper couple 11:364 Reduction 17:495 of substrate 17:495 Reductive acetylation 4:232,324 Reductive alkylation 10:409 of o~(phenylthio) methyl enone 10:409 Reductive amination 1:253,289,290, 301 ;11:302,350,429,437,438,445, 446,450 with acetone/cyanoborohydride 11:301,302 of 1,4-diketones 6:437,438 of ketones 6:429 of triketones 6:445,446 of 2,6,9-undecatrione 6:450 Reductive aminocyclization of alkane-2,6-diones 6:433,434 Reductive cleavage 1:439 with LAH 1:439 Reductive cyclization 1:106,279,281 indolizidine from 11:241,242 of ketones 11:241,242 Reductive decyanation 6:431,432 of 2,6-dialy-2-cyanopiperidi nes 6:431,432 Reductive demercuration 14:185 Reductive desulfurization 12:81,167, 307-309,319 Reductive elimination 19:6 of acyloxysulfones 4:522 of allylic radicals 4:525 with low valent titanium 4:521-535 with zinc copper couple 4:119 Reductive hydrolysis 19:155 Reductive methylation 4:55;6:553,554 Reductive N-methylation 6:435,443 in ant alkaloids synthesis 6:435,443 Reductive opening 1:519 with Et3A1C1-CH2C12/Et3SiH 1:519 Reductive oxygenation 10:532 with NaBH4-DMF-O2 10:532 Reductive ozonolysis 4:523
Reductive rearrangement 3:253 of 3,4,6-tri- O-acetyl-D-glucal 3:253 Reductive transposition 6:11 in (_+)-pachydictyol-A synthesis 6:11 Reformatsky reaction 1:41,312,313, 520;8:232; 14:478,727 ;20:569 of ethyl bromodifluoroacetate 16:727 of chiral 2-bromopropionic acid derivative 12:166 [3-selectivity of 12:167 with 4-acetoxy [3-1actam 12:166 vinylogous 3:38,39 Regio-pyranocoumarins 18:993 Regioselective 11:315,316 ketalization 11:315,316 oxymercuration 11:324 ring expansion 11:280,281 Regioselective acylation 12:346,404 Regioselective alkylation 6:546,547 Regioselective aza-annulation 18:319, 327 Regioselective dehydration 13:561 Regioselective Diels-Alder reaction 14:48 Regioselective glycosidation 6:262 Regioselective hydroboration 13:130 Regioselective Michael addition 18:319 Regioselective nucleophilic substitution 18:406 Regioselective phosphorylation 18:399 Regioselective reactions 24:3,9,10,742 O-methylation 24:742 radical carbocyclization 24:3 reduction 24:9,10 Regioselective reduction 6:289,290 Regioselective tosylation 12:218 Regioselective [3-glycosylation 10:477 Regioselectivity 4:118,142,372,373,391 in Diels-Alder reactions 4:584-586 of C-aryl glycoside 11:142 of 2-substituted 1,2,3,4tetrahydronaphthalene acetate 11:118 of Claisen rearrangement 4:368,
961 369 of Friedel-Crafts alkylations 4:391 of hydroboration 4:116 Regiospecific cleavage 11:267,268 of oxirane ring 11:267,268 Regiospecific enolization 12:84 Regiospecific lithiation 6:509,510 of l-(phenylsulfonyl) indole 6:509,510 Regiospecific oxidation 6:508 of ellipticine 6:508 17-oxoellipticine from 6:508 Regiospecific sulphonation 4:633 of camphor 4:633 Regiospecificity 4:391 of Friedel-Crafts allylations 4:391 Reich-Sharpless reaction 24:194,195 Reimer-Tiemann reaction 2:67,68 J3C-relaxation measurements 2:67,68 ~H-Relaxation measurements 2:67,68 of phenol 8:33,34 trans-Resveratrol 27:768 homooligomers of 27:768 Retro aldol process 19:194 Retro Diels-Alder cleavage 5:634; 9:295,300 Retro Diels-Alder fragmentation 4:40,41 to secodine 4:40,41 Retro Diels-Alder reaction 4:614,615 synthesis of actinidine 4:614,615 synthesis of o~-caryopterone 4:612-614 synthesis of crotepoxide 4:162 synthesis of epiepoformine 4:612,613 synthesis of epiepoxydon 4:610 synthesis of epoformine 4:612 synthesis of epoxydon 4:610 synthesis of ligularone 4:615 synthesis of petasalbine 4:615 synthesis of phyllostine 4:610 Retro Diels-Alder reaction 24:721,722 Retro Michael reaction 14:748 Retro[2+2]cycloadition 19:221 Retro-aldol degradation 12:216
Retro-Aldol fragmentation 12:212 Retro-Aldol reaction 7:286,288,291 ; 10:168,303,329;18:284,285 Retro-aldolisation 4:4,7,56,14:180 Retro-Diels-Alder fission 21:556 Retro-Diels-Alder reaction 21:387 Retro-ene reaction 11:46,47,16:246 Retrograde aldol reaction 6:78 Retrograde Michael reaction 6:173,187, 199,200 Retro-Mannich reaction 1:157,158; 6:497;10:99,333,682;11:55,56; 13:181,397,423,460;18:18 of O-quinol acetate 16:521 Retro-Michael elimination 12:490 Retro-Prins reaction of 16:248 Retrosynthetic analysis 27:189 of hemiacetal ethers 27:189 Retro-Wittig reaction 18:78,176 Reverse Michael addition 3:473,25 Rh (II)-catalyzed carbenoid insertion 13:501,502 Rhazinilam synthesis 29:371,401 by L~vy and co-workers 29:373 by Smith 29:371 Emde degradation in 29:373 mCPBA oxidation in 29:373 by Baudoin-Gubritte 29:407 by GuOritte and co-workers 29:407 by palladium-catalyzed biaryl coupling 29:407 by Smith 29:402 challenges in 29:401 iminium intermediate in 29:405 of (-)-rhazinilam by Sames 29:404,405 of (+)-rhazinilam by Magnus 29:406 of phenyl-pyridine analogues 29:410 of phenyl-pyrrole analogues 29:406 quaternary C-20 stereogenic center in 29:403 racemic type of 29:401 rhaziniliam analogues obtained by Suzuki-Miyaura biaryl coupling 29:410
962
Schiff base formation in 29:404 Suzuki coupling in 29:409 using Gupton methodologies in 29:406 using the Barton-Zard reaction in 29:406 (-)-Rhazinilams 29:362 semi-synthesis of 29:363 synthesis of 29:364 Rhodium 6:424 catalytic hydrogenation with 6:424 Rhodium (1) 1:177-179 decarbonylation by 1:177-179 Rhodium catalyst 4:436 in carbene insertion reaction 4:436 Rhodium catalyzed isomerization 4:22,23 Rhodium III chloride 22:222 Rhone-Poulenc 28:71 vitamin A synthesis by 28:71 Rieke's zinc 13:146 Rifamycin S 23:57,60,84 preparation of 23:57,60,84 Ring cleavage 16:139 of (+)-9,10-dibromocamphor 16:139 Ring cleavage reactions 4:667-673 of camphor 4:667-673 of camphor derivatives 4:667-673 Ring closure 11:10 by Mitsunobu procedure 11:10 Ring construction 3:226,310;6:474, 475,482 by diazotization 3:225,226 in benzazocine derivative synthesis 6:468-471 in benzoxazocine derivative synthesis 6:468-477 intramolecular 11:42,43 nine-membered rings from 6:474,475 of furanosyl nucleoside 10:592-595 of lactone triflate 10:605 oxetanocin A synthesis by 10:592-595
thermal 3:310 to eight-membered rings 3:67,77 to nine-membered rings 3:76 to oxetane-2-carboxylate 10:605 Ring destruction 6:468-471,475-497 by CNBR-induced reaction 6:476,477,484,486 by chloroformate ester-induced reaction 6:477 by photosolvolysis 6:475,476 in benzazocine derivative synthesis 6:468-471 in benzoxazocine derivative synthesis 6:468-471 nine-membered rings formation by 6:468-471 of tetrahydroisoquinoline systems 6:477 Ring enlargement 10:232,233 by migration 10:232,233 by rearrangements 10:232,233 Ring expansion 6:468,472,477,478; 11:6,7,28-31,109 regioselective 11:6,7 2,4-benzoxazocine derivatives from 6:469 in aporphine alkaloids 6:469 in (_+)-spiniferin-1 synthesis 6:73,74 of erythrinan-3-one 6:477,478 of c~-narcotine N-oxide 6:468 Ring interconversion 6:468-475,478, 482-497 in benzoxazocine derivative synthesis 6:468-471 nine-membered rings from 6:468-471 Ring opening 12:411,413 2-amino alcohol by 12:411,413 of oxirans 12:411,413 with nitrogen nucleophiles 12:411,413 Ring transformation 10:303-336 Ring transposition procedure 6:374,375 Ritter reaction 11:281,282 Hg(II)-mediated 11:281,282
963
Robinson annelation 1:17-21,29,8 l, 446,478;6:18,30,56,57,58,55,148, 182;11:33,78,93-96,108,678,679 bicyclic enone from 14:678,679 of (+)-carbomenthone 6:547,548 of 2-carboethoxycyclohexanone 14:678,679 of ethyl vinyl ketone 14:678,679 of cycloheptenone enolate 6:29, 30 of ethyl vinyl ketone 6:19 of 2-methyl- 1,3-cyclohexadione 6:19 trimethyl decalone by 6:19,20 Robinson annulation reaction 14:406-425 chiral sesquiterpenes from 14:406-425 Robinson-Schopf condensation 1:294, 295 Rosmanol (abietane diterpene)synthesis 29:575 from carnosolic acid 29:575 Rubottom epoxidation 11:75 Rubottom oxidation 12:215 Ruthenium (III) chloride 12:162 Ruthenium tetraoxide 1:27,28;22;230 Ruthenium-catalyzed oxidation 12:175 Rydon bromination 6:287,288 Rylander oxidation 12:198 Salicylic acid 27:63 generation of 27:63 Salvianolic acids 30:221 synthesis of 30:221 Samarium iodide mediated cyclization 8:232 SAMM 2 23:30 chemical degradation of 23:30 Sandrosaponin I-X 27:678 sulfate olefaction of 27:678 Saponification 6:146,162,445,447; 19:322 Saponins 27:673,678 oligosaccharidic moiety of 27:524,673 sulfate olefaction of 27:678 Sarett oxidation 14:635
Sarett reagent 4:434;6:27,28 Sarmentosin 21:737,738,739,740 synthesis of 21:739,740 Saucy-Marbet rearrangement 10:417 Schill's synthesis 14:861,862 of vinblastine 14:861,862 Schlessinger 29:370,384 steganes synthesis by 29:370,384 Schlosser-Wittig reaction 16:482 Schmidt reaction 16:472 intramolecular 16:472 Schmidt rearrangement 13:95;16:472; 29:365 in allocolchicinoid synthesis 29:365 Schoellkopf reagent 10:653,655 chiral induction with 10:653, 655 Schollkopf system 4:125 Schollkopf's isocyanides 10:88 c~-metalated 10:88 Schotten-Baumann acylation 10:131 with 2,2,3-trimethylethanolamine 10:131 Schotten-Baumann reaction 11:448 Schreiber' s synthesis 30:6-10 of (+)-discodermolide 30:6 Scopadulan- type diterpenoids 21:706-717 synthesis of 21:706-717 Scopadulane-type diterpenoids 21:706 synthesis of 21:706 Scopadulan-type diterpenoids 21:721-723 biosynthesis of 21:721-723 SE Additions 10:17-25 Secologanin 26:113,114,119 coupling reactions of 26:113, 114,119 Secologanin 26:97,99 chemical transformation of 26:97,99 Selective acylation 12:346;13:586; 14:163 Selective aldehyde reduction 13:579 Selective benzoylation 13:557;14:244 Selective cleavage 7:155 of bisdesmosides 7:155 of ester type glycoside linkage
964
7:154,155 of glucuronide linkage 7:156-158 of sugar aglycone linkage 7:154-158 Selective cytotoxicity 13:648 Selective deoxygenation 14:160 of maltose 14:160 of primary alcohol 16:348 Selective deprotection 12:345 l-Selective glucosylation 15:28 Selective heteronuclear J-resolved spectroscopy 2:147 Selective hydrogenation 6:83 in (+)-9-isocyanopupukeanane synthesis of 6:83 with iridium black 6:83,85 Selective hydrolysis 12:343;13:571 2D Selective J-resolved spectra 2:115 Selective ketalization 6:33;24:175 Selective mesylation 12:326,335 Selective monotosylation 13:620 Selective O-methylation 12:485 Selective reaction 6:282,283 acylation 6:282,283 esterification 6:276 formation of cis-5-oxo- 1indanones 6:558 hydrolysis 6:285,286 Selective redox reaction 20:817-881 chiral synthesis by 20:817-881 Selective reduction 14:145;24:9,10 of methyl 4,6-O-benzylidene-2,3di-O-tosyl-c~-D-glucopyranoside 14:145 Selective silylation 12:330 K-selectride 12:475 of triol 4:184 Selective silylation 24:30-32 Selective skeletal rearrangement 14:377 Selective synthesis 18:315-386 of 8-1actams 18:315-386 of pyridones 18:315-386 c~-Selective thermal glycosidation 8:367 of cyclooligosaccharide 8:367 of cyclo-L-rhamnohexaose 8:367
(z-Selective thermal rhamnosylation 15:28 Selective thiocarbonylation 14:162 of sucrose derivative 14:162 with thiocarbonyl diimidazole 14:162 Z-Selective Wittig olefination of 4:125 erythro-Selectivity 4:143 endo-Selectivity (UL-addition) 6:549, 550;8:411,415-417 syn-Selectivity 12:58 to (2R)-methyl aldehyde 12:58 threo-Selectivity 4:130,145 in cyclocondensation 4:130,145 K-Selectride 14:179 anhydride reduction with 3:489 in stereoselective reduction 4:437,459 L-Selectride 16:454;19:72,419,478,494, 629 reduction with 4:470,516;6:38, 39;14:378,379;18:235 Selenation oxidation 6:74,75 in (-)-pseudopterosin-A synthesis 6:74,75 Selenium dioxide 1:549,550;22:222 for allylic oxidation 1:549,550 Selenium dioxide oxidation 1:74 ~x-Selenoalkyllithiums 8:5,11 as key intermediates 8:3 c~-Selenobenzyllithiums 8:3,5,11 Selenocyclization 11:98,99,101,102 Selenoetherification 10:207;11:109 Seleno-lactonization 13:622,623 Selenoxide-based elimination 1:248 Selenylation 1:452;6:70 Semi synthesis 29:363 of (-)-rhazinilams 29:363 Sepulchre's method 19:367 Sequential Horner-Emmons condensation 13:608 Sequestration 17:93,104 Serendipitous deconjugation 12:28 Serial Michael additions 14:756 Serotonin (5-HT) synthesis 30:370,376, 377 from tryptophan 30:370
965 Sesamin 24:755 synthesis of 24:755 Sesquiterpene lactones 24:799 Sesquiterpenes 24:175-213,847 synthesis of 24:175-213 Sesquiterpenoids drimane-type synthesis 29:127 by Jauch 29:127 Cieplak's theory in 29:127 enantiospecific total- 29:127 endo selection in 29:127 rt-facial selections in 29:127 Horner-Emmons carbon elongations in 29:127 starting from 2,3-anhydro-Darabinitol derivative 29:127 tetracyclic intermediate in 29:127 use of Sharpless asymmetric epoxidation strategy in 29:127 Shapiro reaction 13:509,578;22:238 Shapiro reaction, modified 1:460,461 Shapiro synthesis 11:84 Sharpless asymmetric dihydroxylation 16:332;18:197;20:592 Sharpless asymmetric epoxidation 1:265,266,487,488,507,508,510,532, 538;4:496;10:534,598,599;12:11, 18;13:621 ;14:568-571,828;16:296, 342;16:492;18:217;19:431,435,443, 478;20:450;21:422 diastereofacial-selective manner 19:492 dihydroxylation of 19:246 of 2-ethyl-2-propen-l-ol 14:828 of 2-heptenol 19:61 of allylic alcohol 10:534 of allylic alcohol 12:11 of allylic alcohol 19:45 of geraniol 19:139 osmium-catalyzed 19:246 pyrrolidines from 14:568-571 regioselective manner 19:492 Sharpless epoxidation 4:173,174,179, 186,187,203,339-345,506,514,516; 6:268,269,287,289; 10:39,40,66; 11:7, 8,59,60,83,93,94,267,268;14:746; 18:197,204,205,244
(+)-nitramine by 14:746 enantioselective 4:343,344;6:287 of l-cyclohexenyl alcohol 14:746 of allylic alcohols 4:312,516 kinetic resolution by 4:342 Sharpless epoxidation 6:287 transesterification 13:53,54 Sharpless hydroxylation 12:218 Sharpless kinetic resolution 10:236 of (+)-N-benzyloxycarbonyl-3hydroxy-4-pentenylamine 12:281 Sharpless method 4:483 in thienaycin synthesis 4:483 Sharpless oxidation 24:748 4:602;10:289;12:353 ;16:296,342; 19:463 of I]-hydroxyl olefin 16:296 with diethyl L-(+)-tartrate 16:342 in (_+)-precapnelladiene synthesis 6:34 Sharpless reaction 13:203,204;19:375 Sharpless vicinal hydroxyamination 12:219 [l,5]-Shift 3:34 of cis-alkyl vinylcyclopropanes 3:34 1,2-H Shifts 1:331,332 (+)-Shikimic acid derivatives 29:478 van der walle approach to 29:478 Shine-Dalgarno sequence 13:262 Shing and Wang 29:485 activity of 30:380 decarboxylation of L-dihydroxyphenylalanine 30:371,380 valiolamine synthesis by 29:485 [ 1,2]-Sigmatropic (Stevens) rearrangement 6:315 Sigmatropic 1,3-H-migration 18:166 [2,3]-Sigmatropic elimination 12:11 of PhSeOH 12:11 [l,5]-Sigmatropic H shift 10:70 Sigmatropic migration 19:208 phenylselenium 19:208
966
[2,3]-Sigmatropic rearrangement 1:401,560;3:354;6:316;8:209;11:15, 16,24,30,45,46,48,49,188,326,327; 12:93,95,467;13:72,418,519,589; 14:533,534;16:173,255,621, 622-623,627;19:259 for C-S to C-O conversion 1:560 of allylic sulfonium ylide 16:255 of sulfoxides 1:560 of allylic sulfoxides 11:326,327 of 6-alkenyl-4-oxapyran-2-ones 10:460 of allylic (alkyl) ketene acetal 10:417 of allylic azides 10:418 of allylic thiocyanates 10:418 of allylic trichloroacetimidates 10:421 of allylic sulfoxides 11:326,327 suprafacial 16:627 [3,3]-Sigmatropic rearrangement 1:53, 228,401 ;3:228;4:522;6:222,224,225; 8:245,251;10:333,416-420;11:15, 16,45,46,48,49,188;12:95,193,249; 13:418,519,589;14:625;19:6 Sigmatropic rearrangement 12:246-250; 13:420,564 ;16:340 [ 1,3]-Sigmatropic rearrangement 16:254,617 [3,3]-Sigmatropic rearrangement 24:4, 67,68,81-83 [2,3]-Sigmatropic rearrangement 24:67, 68 [1,5]-Sigmatropic rearrangement 4:333; 11:27,3:289 [3,3]-Sigmatropic rearrangements 21:386 [1,7]-Sigmatropic shift 2:128 [1,5]-Sigmatropic shift 24:763 [ 1,5]-Sigmatropic shift of hydrogen 12:182 [3,3]-Sigmatropy 10:235 Sih's compactin synthesis 13:593 Silicon ethers 6:262 in glycosidation 6:262 Silicon-containing nucleophiles 14:472 Siliconizing agent 22:375
Siloxane bridged oligonucleotides 13:271 13-Siloxyacetals 14:483 with organometallic reagent 14:483 [1,3]-Siloxy-Cope ring expansion 8:246 Siloxydiene 4:334 asymmetric Diels-Alder reaction with 4:34 Silver (II) oxide 5:769 oxidative demethylation with 5:769 Silver cyanide 12:113 allyl isocyanide from 12:113 Silver oxide 11:86 oxidation with 11:86 Silver oxide method 4:386 in prenylation methods 4:386 Silver staining 17:396 Silver sulphamate 9:433 Silver triflate 3:216 in C-glucosidation 3:216 Silver trifluoroethane sulphonate method 4:323,324 Silyl enol ether 3:129 reaction with l-phenyl-2-buten1-one 3:129 reaction with unsaturated ketones 3:129 Silyl enolate Claisen rearrangement 1:563;2:685 Silyl group 1:452,453 removal with n-Bu4 NF 1:452, 453 Silyl ketene acetals 10:422,423 Claisen rearrangement of 10:422,423 O-Silyl ketene acetals 3:243 in Claisen rearrangemment 3:243 Silyl Pummerer rearrangement 4:550 Silylacetylenic reagents 14:473 Silylated phosphonium ylides 4:546 reaction with acid silyl esters 4:546 synthesis of 4:563 Silylation 6:16,19,20,25,26,30-33, 39-41 ;11:338,369;19:518 Silylenol ethers 4:475-477
967 c~-Silyloxy (E)-enone 19:59 03- Silyloxy propargylsilanes 10:227 by exocyclic ring closure 10:227 synthesis of 10:227 Silyloxydienes 4:113 in cyclocondensation 4:113 Silyl-Wittig reaction 14:461,463,464 Silymarin 5:496;13:660 Silyvinylalane 12:295 Simmons-Smith cyclopropanation 6:72;11:29,30;16:703 Simmons-Smith reaction 6:5,234,235; 8:34;14:490;24:190 annulation by 6:5 diastereoselective 14:487-489 of chiral vinyl ether alcohols 14:487,488 of ct,13-unsaturated acetals 14:489-491 Simmons-Smith reagent 14:490 chelation controlled delivery 1:637 cyclopropanation with 1:631,632 Sinapyl alcohol 27:760 polymerization of 27:760 Singlet oxygen 3:439,440 addition to isoquinolines 3:439,440 as dienophile 4:612 Siteselective -lithiation 24:9 Six-membered ring 8:175 Six-membered cyclic ethers 10:209 by rhodium carbenoid mediated cyclization of hydroxy ct-diazo13-keto esters 10:209 Skaanderup and Madsen 29:496 carbaoxirose/carbaoxetoses synthesis by 29:496 Skeletal rearrangements 7:159-168 Smiles rearrangement 23:415 Smith 29:371,402 rhazinilam synthesis by 29:371 Smith rhazinilam synthesis by 402 Smith degradation 1:436,439;5:197 Smith indole synthesis 1:155 Smith reaction 7:270
Smith synthesis 12:25,26 of avermectin oxahydrindene subunit 12:25,26 Smith' s synthesis 30:13-19 of (-)-discodermolide 30:13-19 SN~-products 11:319,320 S N 2 reaction 11:207;14:747;16:296 of triflate 16:296 SN2 type cyclocarbamation 12:479 SN2-alkylation 13:585 SN2-displacement 13:589;14:156 SN2-nucleophiles 16:415 SNZ-type condensation 14:147 SN2-type reaction 14:269 SNAr reaction 20:410 SN'-process 11:323 intramolecular 11:323 Snyder et al. 29:214 miltirone synthesis by 29:214 Soda Fabrik 28:71 synthesis of 29:439 vitamin A synthesis by 28:71 Sodium amalgam 11:349 desulfonylation with 11:349 Sodium artesunate 13:657 Sodium bistrimethylsilylamide 6:540 cyclization by 6:540 Sodium borohydride 8:468-470 Sodium cyanoborohydride 11:87 reduction with 11:87 Sodium hexamethyl disilazide (NaHMDS) 13:63 methylation with 13:63 Sodium hexamethyldisilazide 24:24,25 Sodium hydrotelluride 11:81,82,92,93 reduction with 11:81,82,92,93 Sodium methanethiolate 6:340 Sodium naphthalene 11:371 Sodium naphthalenide 6:541,542 Sodium phenylselenide 6:489,490 reaction with (+)-canadine 6:489,490 Sodium triacetoxyborohydride reduction 22:279,286 Soft acids/bases 3:409 Sowden method 4:197,203 in L-glycero-D-mannoheptose synthesis 4:197,203 Sphingolipid biosynthesis 22:248
968
Spiro [5.5] undecane group 6:59-65 construction of 6:59 Spiro systems construction 6:60-65 by intermolecular cyclization 6:59 Spiroannelation 4:7,12;14:546 in bromochamigrene synthesis 6:60,61 of cyclohexanone aldehyde 6:61 of phenolic ~-diazoketone 6:60,61 Spirocyclic core 21:391 synthesis of 21:391 Spirocyclic systems 6:59-65,85 Spirocyclization 10:170;14:649,755; 16:28 enantioselective 14:750 Spiro-dehydration reaction 12:64 Spiroethers 18:269-309 synthesis of 18:269-309 Spiroketal enol ethers 7:220 Spiroketal reduction 18:276,277 with DIBAH 18:276,277 with Silane-Lewis acid 18:277,278 Spiroketals 9:530;13:60 diaxial configuration 1:476 stereoselective synthesis of 14:519-521 Spiroketone 8:288 from ketolactam 8:287 Spiromentins B 29:300 synthesis of 29:300 Spiro-rearrangement 12:99 Splicing reaction 13:261,290 Squalene cyclization 1:655 n-Stacking model 4:609 Standinger reaction 1:352,353 (_+)-Steganacin 29:382,384,392 steganes synthesis of 29:382, 384,388,392, (+)-/(-)-Steganacin 29:387 steganes synthesis of 29:387 Steganes synthesis 29:369,380 by Schlessinger 29:370 from dibenzylbutyrolactone yatein 29:369,371 matairesinol-type intermediate in 29:371
oxidative dimerization of coniferyl alcohol in 29:370 shikimic acid-cinnamic acid pathway in 29:369 by Brown and Robin 29:392 by Enders 29:389 by Kende 29:380,384 by Kende/Schlessinger 29:391 by Koga 29:386 by Krow 29:384 by Magnus 29:389,390 by Meyer 29:394 by Motherwell 29:399 by Raphael 29:382 by Schlessinger 29:384 by Suzuki-Miyaura 29:396 by Ziegler/Brown/Robin 29:391 cross-coupling reactions in 29:396 diastereoselective approach in 29:394,398 driving force for 29:381 Grignard/oxazoline (Meyers biaryl coupling in 29:394 intramolecular oxidative biaryl coupling in 29:384 isomerization studies of 29:380 of (-)-isostegane 29:389 of (-)-steganone 29:393 of (-)-steganone by Molander 29:398 of (-)-steganone by Uemura 29:397 of (+)-/(-)-steganacin 29:387 of (+)-yatein 29:388 of (+_)-steganacin 29:382,384, 392 of (+)-steganone 29:382,390 of natural (-)-steganone 29:392 phenanthrene ring enlargement in 29:382 role of stegane diastereoisomers in 29:382 stereoconvergent type of 29:389 Suzuki biaryl coupling with (arene) chromium complexes in 29:396 Ullmann biaryl coupling in 29:391
969 use of vanadium in 29:391 weaknesses of 29:395 (+)-Steganone 29:382,390 steganes synthesis of 29:382,390 (-)-Steganone 29:397,398 asymmetric synthesis 24:780, 781 by molander 29:398 steganes synthesis of 29:397,398 by Uemura 29:397 transformations and interconversions 24:781-791 Stellettamine 28:687 total synthesis of 28:687 Stereochemical control 29:422 of c~,~'-disubstituted 3piperidinol alkaloids 29:422 Stereochemical inversion 6:178 Stereochemical revision 9:19 of methyl nuapapuanoate 9:19 Stereochemistry of cycloaddition 4:122, 123 in Diels-Alder reaction 4:122, 123 Stereocontrol methods 1:578 Stereocontrolled approach 29:379 to allocolchicinoids total synthesis 29:379 Stereocontrolled syn aldol reaction 13:546 Stereocontrolled synthesis 28:358 of (+)-paraherquamide B 28:358 Stereodifferentiating reactions 16:399 using chiral auxiliaries 4:327345 Stereodivergent process 29:419 decahydroquinoline-type dartpoison frog synthesis by 29:419 iso-6-cassine synthesis by 29:419 3-piperidinol alkaloids synthesis by 29:419 prosafrinine synthesis by 29:419 prosophylline synthesis by 29:419 prosopinine synthesis by 29:419 Stereoselective 24:3,12,15,27-34,45,46, 70-72,742,745,746,759,760,763-765, 773,774,777,778
alkylation 24:12 conjugate addition 24:15 coupling 24:742,745,746,759, 760,763-765 dienone-phenol rearrangement 24:777,778 epoxidation 24:3,27-34,45,46 -hydroxylation 24:70-72 Mukaiyama reaction 24:773,774 of -keto ester 24:759,760 ortho-ester Claisen rearrangement 24:3 radical carbocyclization 24:3 reduction 24:745,746,759,760, 763,765 Stereoselective addition 19:33 in D-glycero-D-galactoheptose synthesis 4:198,199 Stereoselective aldol condensation 6:264,268 Stereoselective arylation 10:345 C-glycosidation 10:345 Stereoselective C-glycosylations 10:373 Stereoselective construction 19:470 of withanolide D-type side chain 19:470 Stereoselective epoxidation 4:505; 6:553,554;11:165,166,172;14:366 of tetracyclic intermediates 14:148-150 Stereoselective glycosidation 8:359 Stereoselective hydrogenation 10:551, 552 Stereoselective intramolecular reductive alkylation 10:541 Stereoselective ketone reduction 13:600 Stereoselective Michael addiction 13:619 Stereoselective pinacol-type rearrangement 15:509 Stereoselective reduction 10:537;11:91, 99,100,103,104,170-172;12:337; 14:72,378,529 by 1,3-asymmetric induction double bond hydrogenation 14:147 of azetidinone 4:437
970
of brasilenone 6:7,8 of chiral I3-keto sulfoxide 14:529 of penicillinates 4:437 of [3-ketoester 6:429,430 with diisopropylamine borane 4:437 with Dipodascus sp. 12:337 with K-Selectride 4:437 with NaBH4 CeC13 3:483-485 with tetrabutylammonium borohydride 3:483-485 Stereoselective ring opening 12:346 Stereoselective synthesis 6:5-38,54;8:9; 12:353,354,467,468;15:243 ;18:193227 cis cyclopentane 8:9 of (_+)-dolasta-1 (15),8-dien- 14 13-ol 6:54 of (+)-eremophilone 15:243 of (-)-swainsonine 12:330 of (+)-castanospermine 12:353, 354 of 3,7-octadien-l-ol- 12:467,468 of acetogenins 18:193-227 of bicarbocyclic fused systems 6:5-38 of carbonolides 11:163-172 of cis-2,6-dialkylpiperidines 6:431,432 of doxorubicin 14:3-46 of forsythide aglycone dimethyl ester 16:294 of leuconolides 11:163-172 of maridonolides 11:163-172 of methyl cyclopentanoid monoterpenes 20:41-46 of natural products 12:445-498 of oligonucleotides 13:275-281 of spiroketals 14:519-521 of tetraponerine-8 6:452 of threo-2-amino alcohols 12:489-493 of trans-2,6-dialkylpiperidines 6:431,432 of vitamin D 10:43-75 of l-oxygenated y-amino acids 12:476-489 trans cyclopentane 8:9
of E retinal 28:74 of diterpenes bioactive 29:169 Stereoselective Wittig reaction 12:312 Stereoselective c~-hydroxylation 9:518 Stereoselectivity 4:161,162,167, 168,170-172,175,178,183,188, 12:452 of oxazolo [4,3-a] isoquinolines 12:452 of (Z)-conjugate esters 4:177,178 of C(3)-monosubstitution reactions 4:653 of (E)-nonenopyranuronate 4:180,181 of osmylation 4:161,162,167, 168,170-172,175,178,183,188 of Wittig reaction 4:175 [3-Stereoselectivity 10:466 endo-Stereoselectivity 4:657,659 Stereospecific- 11:98;12:298 cyclization 12:298 reduction 11:98 Stereospecific cationic cyclization 12:456 Stereospecific deuteration 20:839 Stereospecific hydroxylation 1:404,405 with OsO4 1:404,405 Stereospecific intramolecular-DielsAlder cycloaddition 6:86,87 in 7,20-diisocyanoadociane synthesis 6:86,87 Stereospecific oxidation/reduction 17:484 Stereospecific preparation 12:466,467 of (3E)-3,7-octadien-1-ol 12:466,467 of 6-oxygenated 4~aryldecahydroisoquinolines 12:457,458 Stereospecific reduction 4:234 of ketonucleosides 4:234 Stereospecific synthesis 18:197-202 from chiral pool 18:197-202 Stereospecific ~-glycosylation 30:459 Stereospecificity 14:201-259 of glycosylation reactions 14:201-259
971 Steric effect 27:355 of benzene ring 27:355 Steroid moiety 30:486,487 synthesis of 30:486,487 Steroid moiety synthesis 30:486 acetylation in 30:486 deoxygenation in 30:486 iodonization in 30:486 LiAIH4 reduction in 30:486 ozonolysis in 30:486 Sterols 27:702 from olive oil 27:702 Stetter thiazolium salt method 6:437438 Stevens [1,2]-sigmatropic rearrangement 6:315 Stevens and Bisacchi synthesis 14:684686 of taxodione 14:684-686 Stevens condensation 3:463 Stevens rearrangement 6:497;16:470471 of ring C-homoberberine analogue 6:496 Stilbenes 30:222 oxidation of 30:222 Still olefination 10:157;12:46,47 Still procedure 13:88 Still rearrangement 13:22 Still synthesis 6:47;10:18 of (+)-Ag~12t-capnellene 6:47 of asperdiol 10:18 Stille-type Pd (0)catalysis 16:435 Still's product 6:542 Stork modification 10:185 of Michael addition 10:185 Stork-Boeckmann enone 12:262 Stork's vinyl radical cyclization 12:15 Stowell's iodide 8:146,147 Strecker reaction 6:312 intramolecular 19:36 Strecker-type reaction 10:463 Streptovaricin D 23:64 biosynthesis of 23:64 Stubenrauch's technique 4:414 Styrene 27:753 epoxidation of 27:753 Styrene-quinone reactions 16:551-552
Styrenes 16:551 cycloaddition reactions of 16:561 polymerization of 16:551 Styryl azide thermolysis 3:314,315 Sudha and Nagarajan 29:472 carbaaldopyranoses synthesis by 29:472 Sugar aglycone linkage 7:154,157,158 cleavage by diazomethane 7:155,156 Sugar derived heptosyl bromide 30:440 in KDN synthesis 30:440 in Neu5Ac synthesis 30:440 Sugar-epoxide 14:168 reductive cleavage of 14:168 Sulfate olefaction 27:678 of saponin 27:678 of sandrosaponin I-X 27:678 Sulfated trisaccharide moiety 27:673 c~-Sulfenylacetamide 3:461 cyclization to erythrinans 3:461 trans-Sulfenylation 12:73,76 intramolecular 12:73,76 Sulfide contraction reaction 6:438,439 Sulfidopeptide lipoxins 9:576 Sulfinates 4:490 Sulfinyl carbanion 1:451 c~-Sulfinylesters 4:491-494 in aldol type condensations 4:491-494 synthesis of 4:490,491 Sulfonation 16:127 of endo-3-bromocamphor 16:127 Sultbne anion addition 1:471 to epoxide 1:471 Sulfone coupling reaction 4:526,528 Sulfones 17:91 Sulfbnium ion-induced cyclocarbamation 12:487 Sullbnyl group 6:342 1,3-rearrangement of 6:342 O-Sulfonylation 12:338 Sulforhodamin B 20:524,537 Sult-bxidation 27:752 of methyl p-tolyl 27:752 Sulfoxides 4:489-491;6:310;14:517-519 preparation of 14:517-519 monochlorinated sulfoxide from
972
6:310 synthesis of 4:489-491 Sulfur analogue 12:160,161 by Pummerer rearrangement 12:160,161 from (R)-2-methyl- 1,3-butanediol 12:160,161 Sulfur stablized carbanions 3:81,82 Sulfur-assisted C-C bond formation 6:308 Sulpheno-cycloamination 1:228 Sulphonation 4:628,633,634 of camphor 4:628 of (+)-endo-3-bromocamphor 4:628 regiospecific 4:633,634 Sulphonium ylids 13:144 sigmatropic rearrangement of 13:144 Sulphur trioxide/pyridine complex 30:527 chlorosulphinic acid from 30:527 pyridine from 30:527 Sulphurisation 9:371,372 of 4-t-nonylphenol 9:372 Super-hydride 3:279 reduction with 3:279 Suvanine 28:672 total synthesis of 28:672 Suzuki coupling 21:148;26:1248 of organoboronic acids 16:435 Suzuki coupling reaction 30:19,22 Suzuki methodology 21:382 Suzuki reaction 20:300 Suzuki-Miyaura 29:396 steganes synthesis by 29:396 Suzuki-Miyaura cross coupling 26:74 of 4-bromo- 1-butyl-9borabicyclononane 26:74,75 Suzuki-type coupling 20:445 Swainsonine 27:515 of biogenesis 27:515 Swern method 19:452 Swern oxidation 1:451 ;4:19,200,210, 418,425;5:20,21,254-257,386,447, 449,497,705-708,821-824,826;6:11, 13,21,25,50,57,58,62,66,67,74,75,11, 9,120,129,192,193;8:3-59,64,65,68,
69,81,82,115-135,139,157, 159-172,175-201,205-217,219-256, 261,274,277-282,283-292,315-350, 359-370,373-392,395-406,409-428, 433-463,466,467,478;9:37,224,225, 228,241-243,248,343-369,434; 10:3-42,47,51,52,59,65,69,70, 77-145,155,156,159,166,167,168, 171,180,188,241-302,307-311, 315-317,320-323,330,331,350,351, 386,414,418,419,421,423-428,436, 437,439-448,457-493,507-511, 514-516,532,534,551,552,561, 585-627,629-669,682-685 ;11:3-69, 71-111,117,119-144,151-172, 229-275,277-377,379-425,429-480; 12:9-33,35-62,65-95,113-135, 145-177,181-225,233-274,275-363, 375-383,411-444,445-498;13:2,3,22, 84,108-120,125,132,138,139,142, 165,187-255,264-281,288,289,328, 353-367,383-471,473-518;18:91, 176-178,198,201,210,260,282,283, 297,475,623,633,641;19:22,33,42, 45,62,207,238,296,304,307,341,373, 426,452,473,497-498;20:50,75,592 in synthesis of (-)-warburganal 4:418,425 of (+)- 1O-O-methyl- 18,19dihydrohunter-burnine 14:706-708 of (+)- 11-epiambinine 14:790,791 of (+)-11-epicorynoline 14:785- 787 of (+)- 1 l-epiisocorynoline 14:785-787 of (+)- 16-hydroxy dihydrocleavamine 14:850-853 of (+)- 18,19-dihydroantirhine 14:406-408 of (+)- 18,19-dihydrohunterburnine 14:406-408 of (+)-3-epi- 18,19dihydroantirnine 14:707,708 of (+)-3-epicorynantheidol 14:790,791 of (+)-5-epi-nardol 14:374,375
973
of (+)-alloaromadendrane4b, 10a-diol 14:379-384 of (_+)-alloaromadendrane4c~,10o~-diol 14:379-384 of (+)-alloyohimbane 14:710,711 of (_+)-ambinine 14:788-791 of (+)-bulnesol 14:365 of (_+)-chelamine 14:793-795 of (_+)-chelidonine 14:793-795 of (_+)-confertin 14:362 of (_+)-corynanthediol 14:709,710 of (_+)-corynoline 14:785-787 of (_+)-eburnamonine 14:728 of (_+)-epialloyohimbane 14:710,711 of (_+)-homochelidonine 14:796 of (_+)-isocorynoline 14:785-787 of (_+)-tirandamycin A 14:120123,129-132,134-138 of (+)-tirandamycin B 14:123126 of (_+)-vincamine 14:726 of (_+)-o~-bulnesene 14:364,365 of (-)-( 10R)-hydroxydihydroquinine 14:564,565 of (-)-7-deoxydaunomycinone 14:493,494 of (-)-ajmalicine 14:563,564 of (-)-allo-yohimbane 14:267,277,278 of (-)-ambrox 14:420-425 of (-)-chokol 14:490 of (-)-eburunamenine 14:636 of (-)-eldanolide 14:272,273 of (-)-epi-ambrox 14:420-425 of (-)-eserethole 14:636-638 of (-)-esermethole 14:639 of (-)-Ireland alcohol 14:119,120 of (-)-lardolure 14:487 of (-)-N-acetylamphetamine 14:496,497 of (-)-ochropposinine 14:565 of (-)-physostigmine 14:636-638 of (-)-polygodial 14:413-421 of (-)-selin-I l-en-4c~-ol 14:456-
465 of (-)-talaromycin B 14:538,539 of (-)-tirandamycin A 14:114117 of (-)-trans-cognac lactone 14:272-273 of (-)-trans-whisky lactone 14:272,273 of (-)-warburganal 14:413-421 of (-)-c~-selinene 14:406-413 of (-)-~5-multistriatin 14:273,274 of (+)-africanol 14:487,488 of (+)-arborescin 14:365,366 of (+)-carissone 14:406-413 of (+)-dihydropinidine 14:572,573 of (+)-eburnamine 14:636 of (+)-isoambrox 14:420-425 of (+)-multistriatin 14:267 of (+)-pedamine 14:499 of (+)-PS-5 14:497,498 of (+)-streptolic acid 14:112-114 of (+)-tirandamycic acid 14:110112,127-129 of (+)-yohimbine 14:566,567 of (+)-zaluzanin 14:366,367 of (+)-o~-eudesmol 14:406-413 of (+)-13-eudesmol 14:490 of (E)-olefinic alcohol 19:452 of (l)-c~-santonin 14:406-413 of (R)-(-)/(S)-(+)-3'-methoxy-4'O-methyl joubertiamine 14:501,502 of (S)-2-(6-methoxy-2-naphthyl) propanoic acid 14:473 of (S)-5-hydroxy-2-penten-4olide 14:273,274 of (S)-trans-g-butenyl 14:473 of (S)-y-acetylenic-yaminobutyric acid (GABA) 14:473 of 1,2,4,6-tetra- O-acetyl-2,3d idehydro-3-deoxy-c~D-threo-hexopyranose 14:173 of 1,2,4,6-tetra-O-acetyl-3deoxy-o~-D-lyxo-hexopyranose 14:173 of 1,2-dehydroaspidospermidine
974
14:635,636 of 1,3-diols 16:11 of l 0-hydroxy corynanthediol 14:709,710 of 13-methyltetrahydroprotoberberine 14:790 of 16-carbomethoxyvelbanamine 14:831,832 of 16'-demethoxycarbonyl- 16'epi-deoxy vinblastine 14:850-852 of 2-methyl- 1,6-dioxaspiro [4.5] decane 14:526-531 of 2'-phosphorylated ribonucleotides 14:304-312 of 2-pyrrolidones 14:560,561 of 3,4-anhydro-~-Daltropyranoside 14:170 of 3-arylisoquinoline alkaloids 14:796-799 of 3-deoxy- 1,2:5,6-di-O-
isopropylidene-D-xylo-
hexofuranose 14:172 of 3-deoxy- 1,2:5,6-di-Oisopropylidene-c~-D-ribohexofuranose 14:168-171 of 3-deoxy-D-ribohexofuranoside 14:164 of 3-deoxy-D-ribo-hexose derivative 14:163 of 3-deoxy-hexoses 14:143-200 of 3'-deoxykanamycin A 14:145 of 4-deoxy-D,L-xylohexopyranose 14:178 of 4-deoxy-D-lyxo-hexose 14:158 of 4-deoxy-D-ribohexopyranoside 14:164 of 4-deoxy-hexoses 14:143-200 of 5,6-methanoleukotriene 14:489,490 of 5-carba-levoglucosenone 14:279 of 5-epi-paradisiol 14:454,456465 of 7,8-demethylene sanguinarine 14:783,784 of adriamycin 14:474,475 of aflatoxin M2 14:651-657
of alcohol 16:313,480 of alkaloids 14:632-639 of allylic alcohol 16:261 of ambergris fragrances 14:420425 of aminocyclitol 14:147 of amiteol 14:456-465 of anthracyclines 14:271 of apovincamine 14:635,636 of aspidospermidine 14:632-636 of benzyl 4,6-O-benzylidene-3-
deoxy-~-D-ribo-hexopyranoside 14:153,154 of branched RNAs 14:284-303 of bulgecinine 14:193 ofcalabarbean alkaloids 14:636638 of carbohydrate derivatives 14:659-664 of cardenolide 14:440-444 of catharinine 14:847 of chelamidine 14:796 of chelerythrine 14:773-775,796 of chelirubine 14:777,778 ofchiral alkoxy-allenes 14:480 ofchiral sesquiterpenes 14:406425 of chiral steroid analogues 14:431-444 of chiral vinyl ether alcohol 14:486 of cis-c~,~'-disubstituted pyrrolidines and piperidine 14:571-574 of cleavamine 14:810 of corydaline 14:790 of damascones 14:425-431 of D-and L-lividosamine 14:186193 of daunomycin 14:474,475 of daunomycinone 14:5-8,24-42 of desepoxymethylenomycin 14:602 of dihydrobenzofuranol 14:651 of dihydrochelerythrine 14:773775,796 of dihydronitraraine 14:765 of dihydrosanguinarine 14:793795
975
of diterpenoids 14:639-642 of dl-carbomethoxydihydro cleavamine 14:831-833 of d/-coronaridine 14:847,850853 of d/-dihydrocatharanthine 14:850-853 of eburnamonine 14:632-636 of emetine 14:565 of epilupinine 14:704-709 of epivincadine 14:635,636 of eudesm-1 l-en-4-ols 14:449467 of fagaronine 14:775-777 ofguaiani alcohol 14:374 ofhomoallylic alcohol 19:238 of hydroazulene sesquiterpenes 14:355-387 of ibophyllidine 14:847 of iboxyphylline 14:847 of indole alkaloids 14:632636,703-730 of insect juvenile hormone analogues 14:391-397 of intermedeol 14:452,453,456465 of isoeburnamine 14:635,636 of isokomarovine 14:763 of isolevoglucosenone 14:279 of isonitramine 14:543,743-747 of isoretronecanol 14:737 of isovelbanamine 14:865-869 of isovincadifformine 14:850853 of komarovicine 14:763 of komarovidine 14:763 of komarovine 14:763 of komarovinine 14:763 of lambertic acid 14:640-642 of leurosine 14:811 of lupine alkaloids 14:731-768 of lupinine 14:737,738 of macarpine 14:781-783 of methyl 2,3,6-tri-O-benzoyl-4deoxy-D-xvlo-hexopyranoside 14:158,159 of methyl 2,3-di-O-benzyl-4deo x y-(z-D-xv lo-
hexopyranoside 14:153
of methyl 3-deoxy-4,6-Obenzylidene-D-lyxo-
hexopyranoside 14:167 of methyl-2,3,6-tri-O-benzoyl-4O-(trifluoromethane sulfonyl)I3-D-galactopyranoside 4:164 of minovine 14:635,636 of modhephane 14:490 of monomorine I 14:575 of N-acetyl-D-li vidosamine 14:188,191 of naphtho [2.3.c] pyran-5,10quinone antibiotics 14:271 of naproxene 14:505 of neointermedeol 14:453,454, 456-465 of nitidine 14:775-777 of nitramine 14:743-747 of nitrarine 14:765 of nitraramine 14:751-754 of Nitraria alkaloids 14:731-768 of N-methyl decarine 14:783,784 of oligoribonucleotides 14:283312 of oxaunomycin 14:493-495 of oxychelerythrine 14:773-775 of oxyterihanine 14:775-777 of pandoline 14:831-833 of paradisiol 14:453,456-465 of penta-O-acetyl-Dglucopyranose 14:659-664 of penta-O-acetyl-D-isopyranose 14:659-664 of piperidine 14:553-559 ofpiperidine derivative 14:572 ofpodocarpic acid 14:639-642 of polysaccharides 14:201-259 of Prelog-Djerassi lactoic acid 14:267 of primary alcohol function 19:42 ofpropargylic alcohols 14:473 of punctatin 14:646,647 ofpurpurosamine C 14:268 ofpyrethrin analogues 14:391397 of pyrrolidine 14:553-559,568571 of quebrachamine 14:632-636
976 of quinolizidine alkaloids 14:731-768 of reserpine 14:267 of rose oil components 14:425431 of sanguilutine 14:777,778, 780,781 of sanguinarine 14:793-795 of seco-dehydroabietane 14:642 of securinine alkaloids 14:657659 of serricornin 14:267,275 of sibirine 14:744 of sibirinine 14:742,743 of spiro [4.5] decane 14:544-546 of stereoisomers of eudesm-11en-4-ols 14:456-465 of streptolydigin phosphonate tetramic acid 14:117,118, 132-134 of taxodione 14:667-702 of tetrahydroalstonine 14:563, 564 of tetrahydrocorysamine 14:790 of tetramic acid 14:110 of tetrodotoxin 14:267,276,277 of thalictricavine 14:790 of velbanamine 14:810,865-869 of vinblastine 14:805-884 of vincadifformine 14:635,636 of vincadine 14:635,636 of vincamine 14:635,636 of vincaminorine 14:635,636 of vitamin E and K 14:478,479 of ~-cyanobenzyl alkyl ether 14:473 of c~-linked 3'-deoxy cyclitol 14:147 of ]3-adrenergic blocking agents 14:473 of [3-cyperone 14:406-413 of 13-damascenone 14:430-432 of 13-elemol 14:406-413 of T-citromycinone 14:8-10 of ~-tabersonine 14:847 of primary alcohol 30:45 Swern reaction 4:425;6:125;9:526; 11:90
Swern-Wittig protocol 19:22 Sweroside 26:103,104 chemical transformation of
26:103,104 Swinholide A 26:1229 paterson's synthesis of 26:1229 Syn elimination 16:335,357 of selenoxide 16:335 of trifluroacetate 16:357 Syn hydrostannation 19:62 Syn-enoate 8:140 Syn-epoxidation 16:442 Syn-isomerization 11:220,221 metal ion-assisted 11:220,221 tertiary allylic isomer from 11:220,221 Synthesis 21:161,391,706-717,741-743, 746-748,757;23:813;24:1-47,53-125, 175-213,488,491,573-672,686, 744-755,779,780; 26:635-637,642;
27:197,204,207,778;28:234,331,
332,338,495,503,508,640,670;29: 169,298,299,355,356,421,433;30: 370,485-494,504,608 from c~-amyrin 29:583 from fukinolic acid 29:582 from methyl 3-(indol3-yl)pyruvate 29:231 in vitro 30:608 of lycogalic acid 29:231 of 7-O-ethylrosmanol 29:575 of galactose prodrugs 21:161 of spirocyclic core 21:391 of sopadulan- type diterpenoids 21:706-717 of licochalcone 21:741-743 of huperzine A 21:746-748 ofpeudolaric acid B 21:757 of alpinolide 23:813 of aopinolide 23:813 of analogs of thapsigargin 24:83 of 11 -angeloxy- -santonin 24:69,70 of arbusculin D 24:69 of bursecan 24:754 of (+)-colart N 24:58,59 of (+)- -cyperone 24:116,117 of dehydroisoerivanin 24:61,62
977
of deoxycubebin 24:754 of 1-deoxy-8-epi-wangustin 24:104-106 of l-deoxyivangustin 24:104106 of 8-deoxyvernolepin 24:94, 95,98 of 2,3-dibenzylbutrolactones 24:744-754 of dihydroreynosin N 24:65,66 of dihydrosantamarin 24:6466,77 of 1 -dihydroxyarbusculin B 24:61,62 of 8,12-elemanolide 24:103,104 of elemanolides 24:91-98 of l l-ene-eudesmanes 24:110,111 of (-)-eudesma-3,5-diene 24:116,117 of guainolides 24:80 of hydroazulene 24:80 of 7-hydroxyeudesmanes 24:112 of 11-hydroxyeudesmanes 24:110-112 of 1 -hydroxyeudesmanolides 24:61,62 of l -hydroxyeudesmanolides 24:64 of 7-hydroxyeudesman-6,12olides 24:112 of isoerivanin 24:61,62 of isojunenol 24:109 of (-)-isostegane 24:779,780 of siozonarol 24:188-190 ofjunenol 24:109 of ludovicin C 24:61,62 of 1-oxoeudesma-2,4-dien-ll H12,62-olide 24:65,66 of 9-oxo-6,72H, 11 Heudesm-4-en-6,12-olide 24:79,80 of sesquiterpenes 24:53-125, 175-513 of 6,12-sequiterpenolides 24:5355 of 8,12-sequiterpenolides 24:53, 56,98-107
of (-)-stegane 24:779,780 of (-)-steganacin 24:779 of (+)-steganacin 24:779 of steganone 24:779,780 of tetrahydrofuran derivatives 24:754,755 of (+)-tuberiferm 24:56,57 of yomogin 24:104-106 of zonarol 24:188-190 of alizarin 26:635-637,642 of mannans and oligomers 26:1158 of cyclohemiacetals 27:196 of GDIBOA 27:188,209 of 5-acetyl-DIBOA 27:263,204 of aza analogues 27:207 of natural bioactive alkaloids 27:778 of 8-geranylapigenin 28:234 of paraherquamides 28:331,332 of 14o~-hydroxymarcfortine A 28:338 of 16c~-hydroxymarcfortine A 28:338 of podolactones 28:495 of (_+)-313-hidroxinagilactone F 28:503 of LL-Z 1271 o~ 28:495 of nagilactone F 28:499 of oidiolactone C 28:505 of polycarpamine A 28:640 ofpolycarpamine C 28:640 of agelasidine B 28:670 of agelasidine A 28:670 of diterpenes 29:169 of antiallergic drugs 29:300 of ascocorynin 29:299 of leucomelone 29:299 of polyhydroxy-p-terphenyls 29:298 of polyhydroxyterphenyls 29:300 ofpolyporic acid 29:298 ofp-terphenylquinones 29:299 of spiromentins B 29:300 of terphenylquinones 29:298,299 of terprenin 29:300 of thelephoric acid 29:298
978
of xylerythrins 29:299 of natural bridged biaryls 29:355,356 of (-)-rhazinilams 29:364 of ~x,~x-disubstituted 3piperidinol alkaloids 29:421 of amphibian alkaloids 29:433 of alkaloid 223A 29:439 of isoantibodies 29:542 of fukiic acid (phenolic acid) 29:582 of ~-amyrin linoleate (~-amyrin cis-9,cis- 12-octadecadienoic acid ester) 29:583 of c~-amyrin palmitate (c~-amyrin hexadecanoic acid ester) 29:583 of ~-amyrin linoleate (c~-amyrin cis-9,cis- 12-octadecadienoic acid acid ester) 29:585,586 of lupeol palmitate (lupeol hexadecanoic acid ester) 29:587 of 24-epi-D2 30:490 of 24-epi-D6 30:490 of natural steroids 30:504 of retinoic acid 30:493 of serotonin 30:370 of steroid moiety 30:486 of vitamin D analogues 30:485494 of vitamin D derivatives 30:491 of vitamin D2 30:490 of vitamin D3 30:490,493 of vitamin D4 30:490 of vitamin D5 30:490 of vitamin D7 30:490 of sarmentosin 21:739,740 of pseudopterosins 23:154,158, 180 of gorgiacerone 23:173 of racemic acerolide 23:176 of cleomeolide 23:488,491 of triplolide 23:686 of (+) HON 13:512-513 of (+)- l-epi-slaframine 12:309 of (+)- l-oxoindolizidine 12:279,280
of (+_)-2-oxoindolizine 12:283,284 of (+_)-5-epipumiliotoxin 18:340 of (_+)-6-demethylstatine 13:514 of (+_)-6-epi-slaframine 12:311,312 of (+_)-apovincamine 18:331 of (+_)-cathenamine 13:490,491 of (+_)-cis-l-hydroxyindolizidine 12:279 of (+_)-dihydroanatoxin-A 13:494 of (+_)-elacokanine C 12:289-293 of (+_)-elaeokanine A 12:289 of (+_)-elaeokanine A,C 13:487 of (_+)-epilupinine 13:483,484 of (+_)-eremophilone 15:243 of (_+)-gabaculine 13:509,510 of (+_)-indolyzomycin 12:301330 of (+)-isoretronecanol 13:483,484 of (+_)-mesembrine 13:492,493 of (+)-N -benzyl-20-_ desethylaspidospermidine 18:323 of (-L-_)-nanaomycin-A 11:127130 of (_)-nupharolutine 13:488,489 of (+_)-O-methylpallidinine 12:470,471 of (_)-pleuromutilin 8:418 of (_)-semivioxanthin 11:130,131 of (_)-seychellene 8:412,423425 of (_)-slaframine 12:307-312 of (_)-statine 12:432,433 of (_)-tashiromine 18:353 of (+_)-tetrahydroalstonine 13:490,491 of (_)-tetrangomycin 11:135-139 of (___)-~z-allokainic acid 13:508,516 of (+)-8-coniceine 13:486,487 of (-)-(1R,8aS)- 1hydroxyindolizidine 12:281 of (-)-( 1S,2R,SaS)-indolizidine-
979 I ,2-diol 12:303,305 of (-)- I ,8a-epi-slaframine 12:312 of (-)- 1 +pi-castanospermine 12:333-335,344 of (-)-( I S,2R,XaR)-indolizidine1,2-diol 12303,304 of (-)-8,Xa-di-q,i-swainsoninc 12329-332 of (-)-Xa-e~~i-swainsoninc 12:328,329 of (-)-X-q,i-castanospermi ne 12:344 of (-)-X-epi-swainsonine 12:328 of (-)-alstonerine 13:383 of (-1-anatoxin-A 13:493,494 of (-)-aristcromycin 8: 148,149 of (-)-E-P-santalenc 8: 145,146 of(-)-E-P-santalol 8: 145,146 of (-)-hobartinc 11:28O-283 of (-)-muscone 10:330,331 of (-)-patchoulol 8:423-425 of (-)-peduncularinc 11:284,285; 13:49 1,492 of (-)-pcriplanonc B 8:227 of (-)-phoracantholide I 10:320323 of (-)-specionin 10:425,426 of (-)-Z-P-santalol8: 145,146 of (-)-P-santalene 8: 14.5,I46 of (-)-p-turmeronc 8:5 1-54 of (+)-( lSS)-prostaglandin A2 10:418 of (+)-( I S,8aS)-I hydroxyindolidine 12:28I of (+)-(6R,7S,8S,8aR)Lri hydroxyindolizidinc 12:347 of (+)-(6S,7R,8R,8aR)lri hydroxyindolizidine 12:347,348 of (+)- 1 ,8a-di-epicastanospermine 12:335,336 of (+)-6,7-di-ei~i-castanospermine 121342-344 of (+)-6-deoxycastanosperniinc 12:337,338 of (+)-6-rpi-castanospermine 12:342-344
of (+)-acetomycin 10:443-448 of (+)-allopumiliotoxins 267A 12:297 of (+)-allopuniiliotoxins 339B 12:298-300 of (+)-indoliLidine alkaloids 11:246-267 of (-)-indolizidinc alkaloids 11:246-267 o f (+)-aristofruticosine 11:323325 of (+)-aristoserratine 11:296 of (+)-arktoteline 11:280-283 of (+)-asteltoxin 10:439-442 of (+)-biotin 13:s14-5 16 of (+)-castanosperniine 11:26727 1 of (+)-castanosperminc 12:32 I , 332-342,353,354 of (+)-compactin 11335-377; 13:555-6I5 of (+)-hastanencine 12:472 of (+)-heliotridine 12:472-474 of (+)-isoeremolactone 8:423,425-428 of (+)-makomakinc 11:280-283 of (+)-nicvinolin 11:335-377 of (+)-mevinolin 1356 I of (+)-monomorineI 11:23 1-244 of (+)-picrasin B 11:76,77 of (+)-pseudoephedrine 12:479,480 of (+)-quasin 11:76,77 of (+)-streptamline 13:s14,sI5 of (+)-thienamycin 13:498-504 o~(+)-A’.~ picrasin B 11:76,77 of (+)-a-homono.jirimycin 11:431,432 of (+)-a-santalol 8: 145,I46 of ( 1 +1 )-aldosyl aldoside 8 3 17-327 of ( 1 4 2 ) aldosyl ketoside thiodisaccharidc 8:324 of ( 1 +2) linked thiodisaccharides 8:327,328 of ( I +4) linked thiodisaccharides 8:33 1-338 of (2R,3R)-3-hydroxyelutamic
980
acid 12:477 of (2S,3R)-3-amino-2-hydroxy-4phenylbutyric acid (AHPBA) 12:433,434 of (2S,3R)-~5-hydroxy-L-glutamic acid 12:431,432 of (3R)-7-amino-13hydroxybutyric acid 12:434 of (3R,4S)-4-methyl-3-heptanol 11:415,416 of (3S,3R)-3-amino-2-hydroxy-5methylhexanoic acid (AHMHA) 12:433,434 of (3S,4R)-statine 12:480;13:513 of (3S,4S)-4-methyl-3-heptanol 11:412,413,415 of (d, l)-bulnesol 10:310,311 of (d,l)-trichodiene 10:307-309 of (dl)-acorenone 10:315-317 of (dl)-~-cuparenone 8:3,4 of (E)-3-bromoacrylates 8:150,151 of (E)-trans- 1-hydroxy- 10-vinyl2-cyclodecene 8:196 of (E,E)-diallylic ether 8:176 of (E, Z)-2,6-cyclodecadiene 8:177 of (R)-(-)-homolaudanosin 13:494 of (R)- (+)-tetrahydro-palmatine 10:682,683 of (R)/(S)-homoproline 13:513,514 of (S)-pinanediol 11:410 of (Z)-trans- 1-hydroxy- 10-vinyl2-cyclodecene 8:196 of (~-chloroalkyl) boronic ester 11:410 of (~-haloalkyl) boronic ester 11:425 of 1,2-disaccharide 8:362,366 of 1,3,5-trihydroxyacridin-9-one 13:357,358 of 1,3-dihydroxyacridin-9-one 13:355 of 1,5-dihydroxy-2,3-dimethoxy10-methylacridin-9-one 13:354,355
of 11-hydroxynoracronycine 13:356-358 of 15-tritiated GA3 8:128,129 of 19,10-thio-3-epi-gibberellin A~ 8:125,126 of 19,10-thiogibberellins 8:125 of 19,20-dehydrotalcarpine 13:411,427,428 of 1-aldo-C-glycosides 10:350,351 of l-aryl bicyclo [3,10] hexane derivatives 8:12 of l-aryl-2-methyl cyclohexane 8:9 of l-aryl-2-methyl cyclopentane 8:9 of 1-deoxynojirimycin 12:332 of l-methyl- 1-phenyl-2(methylseleno)methyl cyclopentane 8:7,8 of 1-O-acetyl oxetanose 10:597604 of 1-thio analog of sucrose (13-Dfructofuranosyl 1-thio-c~-Dglucopyranoside) 8:324 of 1-thiosucrose 8:326 of l-thio-~,c~-trehalose 8:318 of I c~,24R-dihydroxyvitamin D3 11:384,385 of 1c~,24S-dihydroxyvitamin D3 11:384,385 of 1c~,25-dihydroxy-(24R)fluorocholecalciferol 10:69 of 1~,25-dihydroxycholecalciferol 26,23(S)-lactone 10:59 of 1~,25-dihydroxyvitamin D2 11:393-395 of 1o:,25-dihydroxyvitamin D3 11:384,385 of 1~,25S,26-trihydroxycholecalciferol 10:69 of 1c~,313-diacetoxy-23,24dinorchola-5,7-dien-22-al 11:398-402 of 1c~,31]-diacetoxy-23,24dinorchola-5,7-dien-22-ol 11:398-402 of 1~,313-diacetoxychola-5,7-
981
dien-24-al 11:398-402 of 1o~,3[3-diacetoxychola-5,7dien-24-ol 11:398-402 of l~-hydroxy vitamin D3 10:59 of 1~-hydroxyvitamin D2 11:381-383 of 1o~-hydroxyvitamin D2 ( 1Shydroxycalciol) 11:380,381 of 1[3-hydroxyvitamin D2 11:402-404 of 113-hydroxyvitamin D~ 11:402-404 of l l3-methylcarbapenem 13:84 of 113-methylcarbapenems 12:145-177 of 2-(c~-hydroxyalkyl) piperidines 12:453-456 of 2-(c~-hydroxyalkyl) pyrrolidines 12:473 of 2,3,4,5-substituted tetrahydrofurans 11:433 of 2,3,4,6-tctra-O-acetyl- 1-Sacetyl- 1-thio-cz-Dglucopyranose 8:316,318 of 2,3-unsaturated- lthioglycosides 8:346 of 2,6,7-trideox-2,6-imino-Dglycero-D-manno-heptitol 11:467 of 2,6,7-trideoxy-2,6-imino-Dg ly c ero-D- gl uc o- hep ti tol 11:467 of 22,23-dihydro- 1(z,25dihydroxyvitamin D2 11:395398 of 24,24-dihomo- 1c~,25dihydroxy vitamin D3 11:385-387 of 24-epiteasterone 18:515 of 24-epityphasterol 18:515 of 25E,26-hydroxy vitamin D2 10:65,69 of 25-hydroxy vitamin D2 10:69 of 25-hydroxyvitamin D3 11:388-393 of 2-allylphenol 8:169 of 2-amino alcohols 12:411-444 of 2-deoxy-24-epibrassinolide
18:515 of 2-deoxy-2-desmethylene bicylomycin 12:87 of 2-deoxy-3,24diepibrassinolide 18:515 of 2-flurorostradiol 5:447,449 of 2-hydroxy-6-methylbenzoic acid 9:347,350 of 2-hydroxyindolizidines 12:283,284 of 2-isocephems 12:126,127 of 2-iso-oxacephems 12:128,129 of 2-1ithio-2-phenyl-6-heptene 8:7,8 of 2-methylseleno-2-phenyl 6heptene 8:7 of 3,13-diacetyl-GA3 8:122,123 of 3,13-diacetyl-GA3 phenacyl ester 8:133 of 3,4-dihydroisoquinoline 8:230 of 3,5-disubstituted indolizidine alkaloids 11:245-259 of 30-methyloscillatoxin D 18:294-309 of 3-amino-5-hydroxybenzoic acid 9:~34 of 3-cyanocephem derivative 12:135 of 3-dehydro-24-epiteasterone 18:512,513 of 3-dehydroteasterone 18:512,513 of 3-deoxy- 1cz,25-dihydroxy vitamin D3 10:70 of 3-deoxyrosaranolide 11:164 of 3-hydroxy-2-hydroxymethyl6-substituted piperidines 12:474 of 3-nocardinic acid 12:118 of 3-thioxylobiose 8:329 of 4 S-13-D-galactopyranosyl 4thio-D-galactose 8:339 of 4~-arylisoquinoline ring system 12:457,458 of 4-acetoxy-13-1actam 12:160162 of 4-aryl- 1,2,3,4-tetrahydroisoquinoline derivative 12:451
982
of 4-aryltetralin-type lignan 18:586-588 of 4-S-D-xylopyranosyl 4-thio-Dxylose 8:338,339 of 4-S-c~-D-glucopyranosyl 4thio-D-glucose 8:331,332 of 4-S-[3-D-galactopyranosyl 4thio-D-glucose 8:335 of 4-S-13-D-glucopyranosyl 4thio-D-glucose 8:336,337 of 5,8-disubstituted indolizidine alkaloids 11:260-267 of 5-amino-7-methoxy-2,2dimethyl chroman 13:358,359 of 5-demethylene-6-deoxybicyclomycin 12:75,76 of 5o~-carbahexopyronoses 13:190-207 of 6(E)-alkylidene-8-hydroxy-8methylindolizidines 12:294,295 of 6(Z)-alkylidene- 8-hydroxy- 8methylindolizidines 12:295,296 of 6,7,8-trihydroxyindolizidine 12:348 of 6,7-dihydroxyindolizidine 12:348 of 6-acetamido-6-deoxycastanosperimine 12:345,346 of 6-deoxy-24-epi-castasterone 18:512,513 of 6-hydroxy-4a-aryl-cisdecahydro- isoquinoline 12:458,459 of 6-hydroxyindolizidines 12:285,286 of 6-O-methylerythromycin A 166 of 6-S-13-D-galactopyranosyl 6thio-D-glucose 8:339 of 6-S-13-D-glucopyranosyl 6thio-D-glucose 8:339 of 7-hydroxy-3-oxoindolizidine 12:287,288 of 7-hydroxy-7-methyl-5oxoindolizidine 12:289 of 7-hydroxyindolizidines 12:286-289 of 7-methyl-2-methylseleno-2-
phenyl-6-octene 8:9,10 of 7-oxoindolizidine 12:286,287 of 7-thiogibberellin A3 8:123127 of 8-(3,5-dimethoxyphenyl) octan- 1-ol 9:339 of 8,14-cedranoxide 8:163-165 of 8-hydroxyindolizidines 12:293 of 9-hydroxyanthracene 11:119 of ~(1 --)4)-linked 4,4'dithiotrisaccharides 8:344,345 of A-62232 8:400 of A-65265 8:399,400 of A-65638 8:400 of abscisic acid 10:167 of acarbose 10:511,515 of acoragermacrone 8:178 of acridin-9-one derivatives 13:353-361 of ACRL toxin 18:178-185 of acyclic amino acids 13:512516 of acyclic bastadins 10:629631,634,635 of adiposin- 1 10:514,515 of adiposin-2 10:514,515 of agelasphin-9b 18:467-469 of AI-77-B 15:412-418 of aklavinone 11:121,122 of alkaloids 8:283-292 of allo-aristoteline 11:318-322 of allopumiliotoxins 12:297-300 of alstonerine 13:383,408, 411,416,-423 of aluminum borohydride 8:467 of ambrucitin 10:386 of amino acids 11:417;13:507516 of amino sugars 13:190-207 of amino-5a-carbadeoxyhexopyranoses 13:203207 of aminoacylheptoglycosides 11:433-435 of amylostatin 10:507-509 of amylostatin XG 10:507, 510,511 of anacardic acids 5:826
983 of anisomelic acid 10:13-17 of antisense oligonucleotides 13:264-281 of arcyriacyanin A 12:382,383 of arcyriaflavin-A 12:376-379 of arcyriaflavin-B 12:379 of arcyriarubin-A 12:375,376 of arcyriarubin-B 12:375,376 of arcyrin/arcyrinin model compounds 12:383 of aristolasicone 11:315-317 of aristotelia alkaloids 11:277334 of aromatic selenoacetals 8:5 of asatone 8:168 of aspochalasin C 13:131, 132,134 of aspochalasin B 13:142,143 of atisirene 10:180 of avermectins 12:9-33 of aziridinomitosenes 13:444 of azocine 8:207 of bastadin-6 10:636-638 of benz[a] anthracene antibiotics 11:134-144 of benzalmalonates 9:224,225 of benzyllithuim 8:5 of beryllium borohydride 8:467 of bicyclo [2.2.2] octanes 8:412417,419,422,423 of bicyclo [3.2.2] piperazinedione 12:71 of bicyclo [5.2.2] piperazinedione 12:84,85 of bicyclohumulenone 8:161-166 of bicyclomycin 12:65-95 of bilobol 9:354 of binaphthaleneterol 8:221-223 of bioactive natural products 13:473-518 of bisabolones 8:39-59 of bis-indolymaleimides 12:375383 of blood group I active oligosaccharides 10:457-493 of blood group i active oligosaccharides 10:457-493 of boromycin 10:414 of branched amino sugar 10:421
of branched pentasaccharide 10:476,477 of branched tetraacetate 10:476,477 of branched trisaccharide 10:474-476 of brasilenol 9:249 of brassinosteroids 18:507-520 of bruceantin 11:71-73,79-95 of butenolides 11:453 of Cja-desmethylcytochalasin D 8:212-217 of calamanenenes 15:251 of calichemicin 12:283 of carbacepham 8:262 of carba-disaccharides 13:219221 of carbapenam 8:262 of carba-sugars 13:187-255 of carbocycles 8:410-422 of carbocyclic oxetanocins 10:608-619 of carbohydrates 11:420-422 of carbonolide 11:158-172 of carbonolide A 11:165,166 of carcinogenic adducts 8:373392 ofcardol monoene 9:354 of carotenoids 20:561 of carpanone 8:168 of carpetimycins 12:135 of casbene 8:16,17 of castelanolide 11:74-76 of cembranes 10:3-42 of cembranoid 8:18-32 of cembranolide 8:16,17 of cembrene 8:15,16 of cembrene diterpenes 8:15,32 of cephalostatins 18:900-902 of cepham derivatives 12:131133 of C-glycopyranosyl-o~-amino acid 11:470-472 of C-glycosides 11:139-144 of chiral allyl boronates 11:393,394 ofchira113-1actams 12:121 of cholesta-5,7-diene- 10~,313,25-
984
triol 11:390-393 of chroman 13:359,360 of civetone 8:224 of codeinone 10:180 of conjugated dienes 8:275 of convergent lactone synthon 13:604 of costunolide 8:175-181 of coumarinolignan propacin 5:497 of crassin 8:19-32 of crassin acetate 10:6,7 of C-sucrose 11:469,470 of cuanzin 8:283-292 of cubitene 8:221,230 of cuparene 8:6 ofcuparene analogue 8:6 of cyanocycline A 10:108-115 of cyanohydrin 8:225,226 of cyclaradine 8:148,149 of cyclic amino acids 13:507512 of cyclodextrins 8:367 of cyclo-L-rhamnohexaose 8:359-370 of cyclooctenone 8:35 of cyclooligosacharides 8:359370 of cyclopropane derivatives 8:11,12 of cyclosarkomycin 8:150 of cycloundecenones 8:214 ofcytochalasin B 10:166; 13:116,117 of cytochalasin C 13:148,199 of cytochalasin D 13:134-139 of cytochalasin G 13:130,131 of cytochalasin H 13:125-129 of cytochalasins 8:213 of d, l-chaparrinone 11:105,106 of D-allo-~-amino acid 11:460,461 of dendrobatid alkaloids 11:244267 of deoxybouvardin 10:640-642 of deoxybouvardin methyl ether 10:640-642 of desmethoxycuanzine 8:285292
of des-N-methylnoracronycine 13:355,356 of desoxyasperdiol 10:29,30 of diacetoxybinaphthyl 8:222, 223 of dibenzylbutryrolactone lignans 5:486 of diborane 8:466-468 of didemnin-A 10:275,276,281 of didemnin-B 10:276,281 of didemnin-C 10:276,281 of dihydroacarbose 10:508 of dihydromevinolin 13:575,608,609 of dihydronapthalene 8:402 of dihydropyrrole 10:112,113 of dihydrothiopyrone 8:207 of diisopropyl (bromomethyl) boronate 11:425 of diquinanes 13:3-52 of disaccharides 11:469 of diterpenes (tumor-promoting) 12:233-274 of dl-camptothecin 12:283 of DNA 8:373-392 of dolaisoleucine 12:477,483486 of dracaenones 5:20,21 of D-o~-aminot~,-~.nic acid 11:459,460 of eburnamonine 8:264 of elaeocanine 12:454 of eldanolide 11:414 of enone 8:279 of ent-4-oxo-2,33dihydrosolamin 18:197 of ent-brefeldin A 8:148,149 of ent-rolliniastatin-2 18:208,209 of enyne 8:280 of enzymes 8:315 of epi-corrossoline 18:200 of epigloeosporone 9:241,242 of epimeric 2,3-epoxy brassinosteroids 18:512 of epipodophyllotoxin 18:597601 of epoxyallylic ether 10:589,590 of epoxysesquiphellandrene 8:57,58
985
of equisetin 13:545-547 of eremophilone 10:436,437 of erythromycin A 12:48-54 of erythronolide A 11:152, 11:153,157;12:46-54 of erythronolide A seco acid 11:154-156 of ethyl 2-methoxy-6methylbenzoate 9:345,346 of exo-brevicomin 11:413,414 of flexibilene 8:16,17 of freelingyne 10:167 of fruticosonine 11:286 of futoenone 8:159 of futoquinol 8:169 of gangliosides 18:486-488 of germacrone 8:178 of gibberellic acid 8:119 of gibberellins 8:115-135 of gibberellins GA4 8:115,119 of gibberellins GAs_s 8:119,121 of gibberellins GAs7 8:121-123 of gibberellins GA60 8:119,121123 of gibberellins GAy 8:115,119 of ginkgolic acid 9:355 of glaucarubinone 11:79,80,105 of gloeosporone 9:228,241 of glutamic acid 11:419 of glycerol 11:392,393 of glycosyl ester 8:66 of glyfoline 13:361-367,375-380 of guggultetrols 5:707 of guianin 8:159 of haageanolide 8:175-181 of helminthosporal 8:162,163 of hernandin 18:579-584 of heteroatom mediated 8:2052 17 of hexalin alcohol 13:601 of hexepi-uvaricin 18:207-216 of higher carbon sugars 11:4294 80 of hobartine derivatives 1 1:309,310 of hobartine- 19-ol 11:309 of homothienamycin 8:262 of humulene 8:156 of hydroxy-amino-acid 12:431-
438 of hydroxylated indolizidines 12:263-275 of I-active oligosaccharide containing lactose 10:477-479 of I-active oligosaccharide containing lactose 10:477-479 of Ii-active oligosaccharide containing mannose 10:477479 ofindolizidine alkaloids 11:229275 of indolo [2,3-a] carbazoles 12:375-383 of ingenol 12:233-345 of inositol phosphates 18:391451 of ionophore X- 14547 A 10:425 of ipsenol 10:188 of isocyanides 12:113 of isodeoxybouvardin 10:644,645 of isodeoxybouvardin methyl ether 10:644,645 of isodihydrofutoquinol 8:169,170 of isodityrosine 10:630 of isoindolone 8:212 of isoingenol 12:234-245 of isolobophytolide 10:10-13 of isolobophytolide 8:205-217 of isomaltoside 11:469-471 ofisomitomycin A 13:35-37 of isopeduncularine 11:284,285 of isoquinoline quinone antibiotics 10:77-145 of isosilybin 5:486 of jatrophone 10:155,156 of K-252c (staurosporinone) 12:379-381 of keto phosphonate 13:560 of kidamycin aglycone 11:135139 of klaineanone 11:74-76 of lacto-N-biose I 10:467,468 of lactone synthon 13:615-628 of lactosamine 10:461-467 of L-allo-~z-amino acid 11:460,461
986
of large ring compounds 8:19-32 of lasalocid A 10:424 of leukotriene B3 10:159 of leukotriene B4 10:168 of lignans 18:551-606 of lignarenones A,B 10:167,171 of lithium borohydride 8:467 of longipinene 8:33,36,37 of L-ribose 11:390,391 of L-xylo-guggultetrol 5:705-708 of L-xylo-octadecane-1,2,3,4tetrol 5:707 of L-(z-aminouronic acid 11:459,460 of macrocarbocyclic 8:16-18 of macrocycle A 10:280,281 of macrocyclic cytochalasans 13:108-120 of macrocyclic semiochemicals 8:219-256 of macrolide 8:176;10:423 of macrolide antibiotics 12:3562 of macroline 13:383,411, 423,424 of macroline-related alkaloids 13:383-432 of maesanin 5:821-824 of melicopicine 13:353,354 of methoxybipyrrole aldehyde 8:273 of methyl (2E,4E)-2,4nonadienoate 10:166 of methyl epijasmonate 8:152157 of methyl jasmonate 8:152-157 of methyl-(z-peracetylhikosaminide 11:449-451 of methynolide 11:158-163 of methyomycin 11:151 of mevinic acid 13:553-625 of mevinoline 13:605 of mitomycin A 13:439-442 of mitomycin B 13:439,441 of mitomycin C 13:440 of mitomycins 13:433-471 of monocyclic 13-1actams 12:120,121
of monosaccharides 13:207-212 of morphine 18:56-98 of mukulol 8:178 of muscone 8:242,243 of mycinolide 11:393,394 of myoporone 15:228 of N,N'-dimethyl-4-desmethylene bicyclomycin 12:68-70 of N-acetyllactosamine 10:461467 of N-alkyl analogues 8:211 of naphthopyran antibiotics 11:127-133 of natural products 8:175201,409-428 of N-benzoyl-iso-serinate 12:223,225 of N-benzoylpyrrolinone 8:212 of neolignans 8:159-172 of neopinone 10:180 of nitrosterene 8:230,232 of N-methylcyriaflavin A 12:377-379 of nocardicine A 12:118,119 of nonactic acid 10:423,424 ;18:229-268 of nonactin 18:260-265 of nonitol 11:464 of nonofuranose 11:458 of nordidemnin-B 10:294-298 of norepinephrine 8:395-406 of octahydroindolizidine-8-ols 12:293 of octahydroindolizine-2-ols 12:283,284 of octahydroindolizine-6-ols 12:285,286 of octahydroindolizine-7-ols 12:286-289 of octa-O-acetyl 1-thio-mannosyl disaccharide 8:320 of octose derivatives 11:462-464 of Ohno's lactone 8:148,149 of oligomeric DNA 8:373 of oligopeptides 10:629-669 of oligosaccharides 8:316 of oligostatins 10:516 of O-methylancistrocladine 8 :228,229
987
of oscillatoxin D 18:269-309 of otonecine 8:211 of oxetanocin A 10:587-608 of oxetanocins 10:585-627 of oxetanosyl chloride 10:604607 of oxycyclopropane 8:34,35 of pantolactone homologue 10:442,443 of papaveraldine 8:263 of penam carboxylic acid 12:127-129 of penems 8:262 of penicillin derivatives 12:129131 of penicillins 12:115,116 of pentacenequinone 11:121,122 of pentacyclic diterpenoids 8:418 of pentalenene 13:6-8 of pepstatin 12:476 of periplanone B 8:156,179182,226,227 of permethyl cyclohexanone 8:4,5 of permethyl cyclopentanone 8:4,5 of persoonol dimethylether 9:355 of petrosterol 9:37 of phenolic lipids 9:343-369 of phenylalanine 11:417,418 of phenyllactate 12:223 of pheromones 9:351 of phorbol 12:245-272 ofphosphatidyl inositols 18:445450 of phosphoramidite 8:388,389 of phosphorylated polprenols 8:64,65 of phosphotriesters 13:272,273 of phyllanthocin 8:280 of phytosphingolipids 18:457490 of picrotoxinin 8:279 of pikronolide 11:158-163 of piperazinomycin 10:638-640 of podophyllotoxin 18:597-601 of polene synthons 20:571,573
of polycycles 8:278 of polycyclic aromatic compounds 11:119-127 of poly-N-acetyllactosamine 10:323 of polyprenyl diphosphates 8:65,68,69,81 of polyprenyl monophosphates 8:65,68,69,82 of polysiloxanes 13:328 of porfiromycin 13:440 of prezizanol 15:248 of protein 8:315 of proxiphomin 13:122,123 of pseudo-disaccharides 13:212216 ofpseudomonic acid 10:425 of pseudo-NANA 13:210 of pseudo-oligosaccharides 13:235-246 of pseudo-trisaccharides 13:212216 of ptilostemonol 8:45,47 ofptilostemonol acetate 8:47 of pumiliotoxin 12:294,296 of pumiliotoxin 251D 12:294,295 of putative epoxyenone intermediate of estradiol metabolism 5:449 of pyrazines 5:254 ofpyrrole formation 8:269 of quassimarin 11:79,80 of quassin 11:73-76 of quassinoids 11:1-111 of quaternary carbons 8:3-14 of quinocarcin 10:125-141 of quinocarcinol 10:120-124 ofR (-)-muscone 8:224,225 of R-(+)-p-carvomenthene 8:49 of racemic compactin 13:562,563 of recifeiolide 8:176 of renieramycin A 10:97-100 ofrifamycin S 12:37,38 of rifamycin W 12:39-47 ofritterazine K 18:900-902 of RNA 13:284,285 of rosaranolide 11:164
988
of saframycin A 10:84-87,92-96 of saframycin B 10:88-93 of saframycins 10:83-100 of sarcophytol B 8:18,19 of secasterone 18:512 of seco-taxane 12:179,180,201 of serine 11:420 of shikimic acid 13:188 of sildydianin 8:166,167 of silphinene 8:165,166 of silybin 5:486 of sinefungin 11:437,438 of sodium trimethoxyborohydride 8:467 of sorelline 11:326,327 of spiroethers 18:269-309 of sterepolide 8:280 of steroid 8:167-174 of suaveoline 13:383,408,411417 of supensolide 8:222,234,236 of swinholide A 18:178-185 of talcarpine 13:383,411,424426 of tautomycin 18:269-309 of taxane 11:3-69;12:181-216 of taxol 12:217-221 of taxusin 11:55-59;12:200,221 of terpenes 8:33-37 of terpenoid alkaloids 8:418 of tetracyclic diterpenoids 8:418 of tetramethoxyturriane 8:228,229 of tetraoxoalkanedioates 11:117 of tetrols 5:708 of thiodisaccharides 8:316-330, 339,342,343,346 of thiolactone 8:205-207 of thiooligosaccharides 8:316,317-330 of thiotrisaccharides 8:340 of threo-(4S,5S)-4-benzylamino5-hydroxy-2-methyl-6phenylhex- 1-ene 12:478,479 of thromboxane B2 10:419 of thymosin al 8:437-446 of thymosin ~l~ 8:447 of thymosin 114 8:447-453
of thymosins 8:437-454 of thymosins B8 8:456,457 of tjipanazole D 12:382 of tjipanazole E 12:382 of trans-7-formyloxy-8amethylindolizidine 12:288 of trans-hydrindane 10:51 of tricarbonyls 8:261-274 of triquinane terpenes 10:426428 of triquinanes 13:3-52 of tunicamycins 11:446-449 of uranium (iv) borohydride 8:467 of urdamycinone B 11:134,135, 142-144 of uridine diphosphate-galactose 10:468 of validamine 13:190 of validamycin A-H 13:228-232 of valienamine 10:507;13:199 of valine 11:418,419 of valiolamine 13:201 of vancomycin 10:661-669 of verrucarol 10:426-428 of verticillene 12:182,183 of villalstonine 13:405 of vinblastine 14:805-884 of vincristine 14:805-884 of vinylsilanes 8:242,243 of vitamin D 11:379-408 of vitamin D aldehyde 10:52 of xylosides 8:362 of Z,Z- 1,4-dienic macrolides 8:242 of zearalenone 13:536-543 of zeralenone 8:176,177 of zygosporin E 13:146,147 of Z-13-y-unsaturated macrolide 8:222,232 of Z-y-unsaturated carboxylic acids 8:239 of A~'7-unsaturated brassinosteroids 18:515-520 of AL7-oxygenated brassinosteroid 18:515-520 of A9(12)-capnellene 13:34,35 of A-benzyl- 1,2,3,4-tetrahydro-
989
isoquinolone alkaloids 10:683-685 of ct-dicarbonyls 8:261-274 of ct-l,4-disaccharide 8:369 of or-amino acid 12:435-438 of o~-copaene 8:33-36 of o~-cyclodextrins 8:367,368 of o~-D-fructofuranosyl-1 -thio-13D-glucopyranoside 8:325,327 of t~-enamino derivative 8:262 of t~-halomethylcycloheptane 8:35-37 of t~-hydroxy-13-amino acid 12:493 of t~-longipinene 8:33,36,37 of t~-mono-alkoxylated piperzinediones 12:84 of 13(1 ---)4) linked 4,4'dithiotrisaccharides 8:347,349 of ~,~-trehalose 8:317,318 of 13-copaene 8:33-36 of 13-galactosidase 8:315,316 of 13-hydroxy ester 11:395 of 13-hydroxy macrolides 8:231,232 of 13-1ongipinene 8:33,36,37 of 13-necrodol 8:279 of 13-sesquiphellandrene 8:45,46,51,55 of 13-turmerone 8:51,52 of y-allenyl-GABA 13:514 of y-aminobutyric acid (GABA) 13:514 of y-dehydro-t~-amino acid 11:471,472 of baogongteng A 21:751,752 of decumbenine B 21:735 of flavonoidal alkaloids 21:130 of glucuronic prodrugs 21:169 of huperzine A from 21:746-748 of licochalcone 21:741-743 of N-methylmaysenine 21:445,446 of pseudolaric acid B 21:757 of sarmentosin 21:739,740 of scopadulane-type diterpenoids 21:706
of spirocyclic core 21:391 reaction with lead tetraacetate 5:21 reaction with tristrifluoroacetate (TTFA) 5:21 via phenolic oxidative coupling 5:21 Synthetic access 27:185-225 to benzoxazinones 27:185-225 Synthetic analogues 29:359 of allocolchicinoids 29:359 Synthetic approaches 4:120;14:805884;20:899-902 of microcystins 20:899-902 of nodularins 20:899-902 to 6-epi-purpurosaine B 4:120 to purpurosamine B 4:120 to vinblastine 14:805-884 to vincristine 14:805-884 Synthetic derivatives 26:162;29:246 of acetylsalicylic acid 26:162 of 413-aminoaniline 26:162 of 2-aminobenzothiazole 26:162 of 2-mercaptobenzothiazole 26:162 Synthetic ecdysteroid analogues 29:19 11~-acyl turkesterone as 29:19 dacryhainansterone as 29:19 2-(4,5-di metho x y-2-hi trobe nzy 1)20-hydroxyecdysone as 29:19 25-fluoroponasterone A as 29:19 26-iodoponasterone A as 29:19 Synthetic fluorinated compounds 29:344 5-fluoro-6-fluoro-substituted alkaloids as 29:344 5-fluoro-Nb-acetyltryptamine as 29:344 5-fluoro-I]-hydroxy-Nb-acetyltryptamine as 29:344 6-fluoro-13-hydroxy-Nb-acetyltryptamine as 29:344 fluorotryptamines as 29:344 Synthetic methods 20:294-307 of biaryls 20:294-307 of diarylethers 20:307 Synthetic reagents 6:307-349 dithioacetal S-oxides as 6:307-
990
349 dithioacetal &S-dioxides as 6:307-349 Synthetic routes 29:227 to arcyriaoxocin A 29:227 Synthetic strategies 29:128,129,130,452 for carbaaldofuranoses 29:452 of kuehneromycin A 29:128, 129,130 Synthetic studies 15:493-500 of humantenine-type oxindole alkaloids 15:493-500 of koumine-type alkaloids 15:500-503 of sarpagine-type alkaloids 15:487-493 Synthetic substrate analogues 7:29-86 in enzyme-carbohydrate interactions 7:29-86 Synthetic type 29:312 of tetracyclines 29:312
Taxodione 24:202-206 synthesis of 24:202-206 Taxoids 24:933 Taxol 24:269,271,276,405,933-972 de novo synthesis of 24:933 TBDMSCi protection 4:388,389 in (+)-5-O-methyllicoricidin synthesis 4:388,389 Tebbe olefination 3:270 Tebbe reagent 14:119;16:226;24:12,19 Tebbe rearrangemet 6:46,47 in (+)-A9~jz)-capnellene synthesis 6:46,47 Telomerizations 12:416 Template selectivity 1:608 Ten-carbon sugars 4:182-187 by epoxide route 4:182-187 by osmylation 4:182-187 Terminal acetylene 27:348 oxidation of 27:348 Terphenyllin 29:296 biosynthesis of 29:296 o rtho-Terphen y lquinone
Takai reaction 30:38,41 Takai's homologation 26:1224 Takano's reaction 12:26,27 of enoate 12:26,27 with cyclopentadiene 12:26,27 Takano's synthesis 14:865-867 of vinblastine 14:865-867 of vincristine 14:865-867 Tandem conjugate addition 24:745,746, 758,771 Tandem Grignard reaction 19:11 Tandem Michael addition 4:556,557 with Cu (I)-tributylphosphine 4:556,557 Tandem Michael-aldol reaction 3:138143 Tandem process (two-stage coupling process) 12:55-58 mechanistic consideration of 12:55-58 Target-oriented (linear) synthesis 29:452 carbaaldofuranoses 29:452 Tautomerization 27:771 of MO4 27:771
phlebiarubrone 29:296 biosynthesis of 29:296 p-Terphenylquinones 29:299 synthesis of 29:299 Terprenin 29:300 synthesis of 29:300 Tetrabutyl ammonium fluoride 11:369 Tetracyclines 29:312 biosynthesis of 29:312 synthetic type of 29:312 Tetrahydropyran 10:339 from Claisen ester enolate rearrangement 10:339 Tetrahydropyrans 1:637 enantioselective synthesis of 1:637 Tetrahydropyranyl ether 6:264,268 protection with 6:264,268 Tetrahydropyranylation 14:694,695 Tetramic acid 28:110 synthesis of 28:110 Tetra-N-butylammonium fluoride 6:119-121 deprotection with 6:119-121 Tetra-N-propylammonium perruthenate 12:312
991
Nt,NS, N~~ 4-Tetra-p-coumaro yl spermidine (phenolic amide) synthesis 29:574 from NI,NS, N:~ coumaroylspermidine 29:574 Tetra-substituted azulenes 14:343-345 oxidation of 14:343-345 Tetrazole-catalyzed reaction 14:288 Tetrazolium blue reagent 19:755 Thallium (III) compounds 20:305,306 Thallium nitrate 4:338 oxidation with 4:338 Thallium nitrate (TTN) oxidation 10:631-635,637,638,640,641,644647,653,654,661,662,666,667 Thallium triacetate 4:72-76 oxidation of 17-hydroxyaspidospermidines 4:74 oxidation of 3-oxo-tabersonine 4:72 oxidation with 4:70-76 Thaumatin 27:9,10 analogs of 27:9,10 Theaflavin 28:274 formation of 28:274 Thelephoric acid 29:296 biosynthesis of 29:296 Thelephoric acid 29:298 synthesis of 29:298 Thermal glycosidation (metal free) 8:361,362,365,366 of allyl glucoside 8:365,366 of allyl rhamnoside 8:365,366 of (+)-baiyunol 8:362 of cholestanol 8:365,366 of cholesterol 8:361,362,365,366 of decanol 8:362,365 of dihydrolanosterol 8:362,365, 366 of geraniol 8:362,365 of glucoside 8:362,365,366 of glucosyl chloride 8:361,362 of mannosyl chloride 8:361,362 of methanol 8:365 of l-methylcyclohexanol 8:365, 366 of methyl glucoside 8:365 of rhamnosyl chlorides 8:361,
362 of xylosyl chlorides 8:361 Thermal [4+2] addition 8:412 Thermal Claisen rearrangement 24:3-5, 29,30 Thermal fragmentation 10:420 of [2'-(phenylselenyl) ethyl] glycoside 10:420 Thermal mannosidation 8:359,369,370 Thermal rhamnosidation 8:359,369,370 Thermally-induced rearrangement 6:468 of I3-hydrastine N-oxide 6:468 of or N-oxide derivative 6:468 Thermolysis 3:314,315;4:626,627;6:472 of 1,5-benzoxazocine N-oxide 6:472 of 2-benzazocine N-oxide derivative 6:472 of camphor- 10-sulphonyl bromide 4:626,627 of (+)-laudanosine N-oxide 6:472 of styryl azides 3:314,315 Thermolytic cyclization 6:429 of alkenyl azides 6:429 of azides 6:429 Thiele acetylation 10:120,121 Thioacetal 14:660,661 hydrolysis of 14:660,661 with cadmium carbonate 14:660 with mercury (lI) chloride 14:660 Thioacetates 28:666 conversion to furodysin 28:666 Thioaldehyde cycloaddition 8:207-217 Thioaldehyde Diels-Alder reaction 8:207,210,213 6-Thioallolactitol 8:353 6-Thioallolactose 8:338,339 Thioallolactose 8:339,342,353 Thiocarbapyranoses synthesis 29:488 by Lew and Kim 29:488 by Rassu 29:489 cr 1:240
992
Thiocarbonate 1:442,443 pyrolytic elimination of 1:442, 443 4-Thiocellobiose 8:332,333,351,352 4-Thiocello-oligosaccharides 8:348,349 Thio-Claisen rearrangement 1:53; 14:865-867 isovelbanamine from 14:865-867 velbanamine from 14:865-867 Thiocyanates 8:316 5-Thio-D-glucose 6:351 4-Thiodisaccharide 8:330,332 Thiodisaccharides 8:317-340 synthesis of 8:317-340 Thiodisaccharides (1-->4) linkage 8:329 1,2-trans 1-Thiodisaccharides 8:317, 318 1-Thiodisaccharides 8:317-326 synthesis of 8:317-326 Thiodisaccharides (1--->2) linkage 8:327 Thiodisaccharides (1-->3) linkage 8:329 Thiodisaccharides (1--->6) linkage 8:338 Thiodisaccharides (6-->6) linkage 8:340 5-Thio-D-mannopyranose 6:351 Thioesters 4:554 acylation of phosphonium ylides 4:554 Thioglycosides 1:429,430 synthesis of 1:429,430 1-Thioglycosides 8:315-317 Thioglycosidic linkage 16:114 2-Thio-hexopyranose-4-ulose nucleosides 4:252 synthesis of 4:252 Thioketalization 14:680,681;24:80 Thiolactone 8:206,207 synthesis of 8:206,207 Thiolester 12:147 with triethyl phosphite 12:147 Thiolester enolates 12:167-170 4-acetoxy-13-1actam with 12:167-170 C4-alkylation with 12:167-170 Thiolesters 8:316 5-Thio-L-rhamnose 6:351 Thiomercury derivatives 8:316 Thionolactones 10:208 by macrolactonization 10:208
desulphurization of 10:208 synthesis of 10:208 Thio-oligonucleotide 13:283 Thio-oligosaccharides 8:316-346 reaction with enzymes 8:315 synthesis of 8:316-346 Thiophene C-glycosides 10:349 from glycals 10:349 2-Thiophenecarbaladehyde 6:322 (2-thienyl)-acetic acid from 6:322 Thiophenol 6:542;14:750 elimination of 6:540 Thiophenolate complex 14:750 non-chelating 14:750 Thiophenyl-glycosides 10:381 allylation of 3:222 Thiophosphoramidites 13:269,270 phosphorodithioates from 13:269,270 Thiosugars 8:315 4'-Thio-toyokamycin 6:351 Thiotrisaccharides 8:340,341 3-Thioxovincadifformine 19:103 2-Thioxylobiose 8:328 synthesis of 8:328 3-Thioxylobiose 8:329 4-Thioxylobiose 8:336 4-Thioxylobioside 8:349 4-Thioxylooligosaccharides 8:348,349 1-Thioxylose 8:336 Thorpe-Ziegler reaction 10:328 Three component reaction 4:572,573 Three-carbon annulations 6:42,49,50, 52,74,75 in (q-)-A 9(12) capnellene synthesis 6:42 in capnellenol synthesis 6:48,50 in dolasta- 1 (15), 7,9-trien- 14-ol synthesis 6:52 Three-carbon ring expansion 10:330, 331 (-)-muscone by 10:330,331 Three-dimensional structure 20:903-907 of microcystins 20:903-907 of nodularins 20:903-907 Threo-2-amino alcohols 12:430,431 interconversion of 12:430,431 stereoselective synthesis of
993
12:489-493 to erythro-2-amino alcohol 12:430,431 Threo-erythro interconversion 12:430, 431 of 2-amino alcohol 12:430,431 Threo-selective reduction 12:300 Tiara et al. 29:198 carnosic acid synthesis by 29:198 Tin (II) enolate 12:164 of achiral thiazolidin-2-thione derivative 12:166 with tin triflate 12:164 Tin acetylide 1:475 palladium mediated acylation 1:475 Tin enolate 12:170 from ketone 12:170 with 4-acetoxy-13-1actam 12:170 with high [3-selectivity 12:170 Tin hydride reduction 12:271 Tin ~-alkoxyanions 3:281 Z-trisubstituted olefins from 3:281 Tin(II) enolates 14:735 thiazolidines from 14:735 Titanium 4:421-535 reductive elimination with 4:421-535 Titanium (IV) catalyzed 12:241 cyclization 12:241 Titanium (O) 11:366,367 by titanium trichloride 11:366,367 preparation of 11:366,367 with potassium graphite 11:366,367 Titanium reagent 3:80,81;11:366,367 application of 11:371 discovery of 11:366,367 in dicarbonyl coupling 3:80,81 Titanium tetrachloride 11:358 Titanium tetrachloride catalyzed reaction 8:141-143,146,151 of acrylate 8:142
Titanium tetrachloride method 4:252 for 6-deoxynucleoside synthesis 4:232 Titanium tetraisopropoxide 4:505 in stereoselective epoxidation 4:505 Titanium trichloride 11:366,367 titanium (O) from 11:366,367 with potassium graphite 11:366,367 Titanium-induced carbonyl coupling reactions 8:15,25,31 Titanium-induced coupling 11:345,368 Titanium-induced intramolecular pinacol coupling 8:18 Titanocene dichloride 10:30 TMAO-urea complex 18:678 2-TMP (2-thiazolyl methylene triphenyl phosphorate) 11:443,444 TMS enol ether 4:8,10,36,38 formmation from ketone 4:8,10 TMS triflate 1:514 TMSOF (2-(trimethylsiloxy) furan) 11:451,453 TMSOTF 1:308;4:91,92 deblocking of BOC 4:91,92 2-TNO (2-thiazolylcarbonitrile Noxide) 11:443,444 Tobagolide 23:172 acetylation reaction of 23:172 Tocopherols 27:700 from olive oil 27:700 (R)-Tolbinap-ruthenium (II) complex 12:153 (S)-Tolbinap-ruthenium (II) complex 12:153 Tollens oxidation 8:25 with AgNO3 8:25 (rc-Toluenesulfonyl) methyl isocyanide (TOSMIC) 3:321,322 double addition of 3:321,322 2'-O-Tosyl-5'-O-trityladenosine 19:519 Tosylation 6:287,288,11:359,19:518 of nucleosides 19:516 co-Tosyloxy-c~-phenylthiocrylontriles 6:540 Total synthesis 26:66,67,69,71,72,75, 77,78,87,90;28:367,502,661,672, 687,709;29:148
994 of 25-oxa-25-phospha-vitamin D3 9:509-528;24:3,5,7,11-15,25-47 ofdestomic acid 4:130 of erythromycin A 12:53,54 of erythronolide A 12:46-53 of galantinic acid 4:127 of koumidine 15:493 of Na-Methyl-D~S-isokoumidine 15:493 of phorbol 12:265-272 of purpurosamine C 4:123 of rifamycin W 12:46,47 of vitamin D3 9:510 of (-)-acetomycin 24:5 of (-)-anastrephin 24:5 of (-)-epianastrephin 24:5 of (+)-eremantholide A 24:5-7, 11,13 of (-)-verrucarol 24:3,25-47 of ( 10Z, 15Z)- 10,15-eicosadienoic acid 26:90 of (R)-22-methyl-5,9-octacosadienoic acid 26:87 of 9,13-dimethyltetradecanoic acid 26:66 of 10,13-dimethyltetradecanoic acid 26:67 of (5Z,9Z)-5,9-hexacosadienoic 26:82 of (Z)-2-methoxy-5-hexadecanoic acid 26:77 of (4E,7S)-(-)-7-methoxy-4-tetra decenoic acid 26:78 of (R)-2-methoxyhexadecanoic acid 26:78 of 11-methyl- 12-octadecenoic acid 26:69 of 7-methyl-6(E)-hexadecenoic acid 26:71 of 7-methyl-6-octadecenoic acid 26:72 of methyl (Z)-2-methoxy-6-hexa decenoate 26:75 of ent-calyculin A 26:1234, 1235-1239,1240 of paraherquamide A 28:331,367 of nagilactone F 28:502 of halipanicine 28:661 of suvanine 28:672
of stellettamine 28:687 of pateamine 28:709 of kuehneromycin A 29:148 of Mniopetals 29:148 of ecdysteroids 29:17 carbaaldopyranoses synthesis by 29:471 TPSTe 4:269 as condensing agent 4:269 Transacetalation 8:287,288;11:82, 83,109 acid-catalyzed 14:654 intramolecular 14:654;11:109 Transannular [2,3]-Wittig rearrangement 8:195- 201 synthesis of costunolide 8:195201 synthesis of haageanolide 8:195201 Transannular [4+2] cycoaddition 5:796, 797 Transannular acylation of sulfur stablized carbanions 3:81,82 medium ring formation by 3:81,82 Transannular cyclization 13:440 Transannular deprotonation 10:222 Transannular Diels-Alder reaction 8:187-195 Transannular ketal cyclization 11:59 Transannular oxidation 29:173,174 in pisiferic acid synthesis 29:173,174 Transannular reaction 8:175,19:66,418 Transannular S N 2 cyclization 15:500 Transcription initiation 5:580 Transesterification 1:267,8:288,292; 21:168 enantioselective 1:685;13:53,54 enzymatic 13:55 of tricyclic lactones 12:30 of propane-l,3-diols 13:53-55 Transformation 23:488,491,503,511; 24:53-62,72,73,78,80,90;27:74 biomimetic 11:292-295 hobartine-aristoteline 11:292295 of bile alcohols 17:217
995 of oxetanocin A 10:586,587 of quinocarcin 10:119,120 of saframycins 10:101 - 103 of cleomeolide 23:488,491 of bacogenin A~ 23:503,511 of artemisin 24:78 of santonin 24:80,90 of santonin to sesquiterpenes 24:53 of 9-hydroperoxy- 10,12,15octadecatrienoic acid 27:74 Transglycosylation 7:54,55,61 Transition states in synthesis 29:161 of kuehneromycin A 29:161 Transketalization 1:415,417,457 Translactonization 8:21,29 intramolecular 13:159 Transmethylation 2:53 inhibition of 1:408 in FAB spectra 2:53 1,3-Transposition 4:165 of allylic system 4:165 Transylidation 4:560,563,564 Traumatic acid 27:75 generation of 27:75 2'-/3'-Trialkyl silyl ribonucleosides silyl migration in 14:285 Trialkylaluminium compounds 1:624, 625 addition to ~z,13-alkynyl acetals 1:624,625 addition to ~z,13-unsaturated acetals 1:624,625 diastereoselective addition of 1:624,625 Trialkylalumnium 6:428 Trianion 1:13 of indole-3-acetic acid 1:13 Tribenzo[a,c,e] cycloheptatrien-5-one 11:125 from diethyl 2,2'-Bi-l-benzoate 11:125 synthesis of 11:125 Tribenzotropone 11:125 Tributyltin radical 1:490 addition to olefin 1:490 (Z)-Tributylvinylstannanes 10:162 cross coupling reactions with 10:162
Tricarbocyclic bridged systems 6:74-86 Tricarbocyclic epoxide 6:37,38 by Saegusa ring expansion 6:37,38 (_+)-dactylol from 6:37 synthesis of 6:37,38 Tricarbocyclic fused systems 6:38-58 stereoselective synthesis of 6:3858 Tricarbonyl (diene) iron complex 12:280 Trichloroacetamidate 6:276,277 from D-glucose 6:276,277 3-Trichloroacetamido-3-C-vinylderivative 10:421 Trichloroacetimidate method 4:207-209 condensation of 4:207-209 cz-Trichloroacetimidates 14:212,213 13-Trichloroacetimidates 14:212,213 Trichloroethyl carbamate 1:71 Trideoxynucleosides 4:525 synthesis of 4:525 Triethyl silane 3:218 reduction of hemiketal 3:218 Triethylammmonium formate 3:184 Pd2 catalysed reduction 3:184 Triethylsilyl silyl ethers 11:339 bis (Triethylsilylacetylene) 10:249 Triethylsilylation 11:363,364 8'-Trifluorinated analog 27:347 8',8',8'-Trifluoro-ABA 27:346 from methyl ester 27:346 Trifluoroacetoxy-selenylation 12:473 3-Trifluoroacetyl-allohobartine 11:318, 319 from allohobartine 11:318,319 N-Trifluoroacetyl-L-acosamine 4:150,151 synthesis of 4:150,151 N- Tri fl uoroac etyl-L-dau no sam ine 4:150,151 synthesis of 4:150,151 Trifluoromethanesulfonates 8:316 4-O-Triflylgalactoside derivative 8:330, 331 synthesis of 8:330,331 14-endo-Trig cyclization 13:589
996
5-exo-Trigaryl radical-alkene cyclization
3:327,328 Triglycosides 7:270,273,275,286,287 Trihaloalkyl protecting group 4:286 removal of 4:286 Trihydroxy fatty acids 27:77 enzymic generation of 27:77 2,4,6-Triisopropylbenzenesulfonyl chloride 4:269 as condensing agent 4:269 2,4,6-Triisopropylbenzenesulfonyl-4nitro-imidazole TPSNI 4:269 as condensing agent 4:269 Trimethyl decalone 6:19,20 by Robinson annulation 6:19,20 from ethyl vinyl ketone 6:19 from 2-methyl- 1,2cyclohexadione 6:19 in euryfuran synthesis 6:20 in pallescensin-A synthesis 6:20 synthesis of 6:19,20 Trimethyl orthoformate 1:448,449 methylation with 1:448,449 Trimethylsilyl enolate 14:572,573 ozonolysis of 14:572,573 piperidine derivative from 14:572,573 Trimethylsilyl cyanide 1:156 in glycosylcyanide synthesis 3:210-212 Trimethylsilyl derivative 4:223 in nucleosides synthesis 4:223 Trimethylsilyl esters 4:564 acylation of phosphonium ylides 4:564 Trimethylsilyl intermediates 4:394 in prenylation methods 4:394 N-Trimethylsilyl iodohydrin 1:277 Trimethylsilyl triflate (TMSOT) 12:419,420 bis-(Trimethylsilyl) hydrogen phosphate 8:69 2,3-bis-[(Trimethylsilyl)oxy butadiene 12:377 1,2-bis-phenylhydrazone from 12:377 with maleimide 12:377 2-(Trimethylsilyl)oxy] butadiene 12:377
2-Trimethylsilyl- 1,3-dithiane 12:156 N-Trimethylsilyl-3- (trimethyl sily) propynal-dimine 4:457 Trimethylsilyl-3-butyn- 1-ol 12:473 Trimethylsilylation 1:272,273 3-endo-Trimethylsilylcamphor 4:663, 664 Trimethylsilyldiazomethane 4:91,92 esterification of 4:91,92 Trimethylsilylisocyanate 3:309 N-acylation ofindoline 3:309 Trimethylsilylmethylation 1:249 Trimethylsilyloxy butadiene 14:751,752 with methylene glutarimide 14:751,752 4-(Trimethylsilyloxy)-13-1actam 12:160, 161 from enolsilyl ether 12:160,161 2-Trimethylsilyloxybutadienes 4:581 in Diels-Alder reactions 4:581 2-Trimethylsilylthiazole (2-TST) 11:443,444 Trimethylsilyvinylalanate reagent 12:295 Triol 4:166 selective silylation of 4:184
N1,NS,Nl ~
y lspermidine
29:574 N 1,N5,N10,N 14 -Tetra-p-coumaroylspermidine (phenolic amide) 29:574 synthesis from 29:574 Triphenylmethyl phosphonium permanganate 3:182 Triphenylphosphine 11:342 Triphenylphosphonium methylide 11:351,352 deprotonation of 11:351,352 with sec butyllithium 11:351,352 N-(Triphenylphosphoranylidene)-~alanine methyl ester 12:301 Triphenyltin hydride 6:427,428 in reductive of selenides 6:427,428 Triphosgene 12:113 isocyanides from 12:113 Triplolide 23:686 synthesis of 23:686
997
Triptolide synthesis 29:200 by Banerjee and Az6car 29:208 by Brchtold et al. 29:200,203 by van Tamelen 29:203 by Yang et al. 29:210 starting material for 29:208 yield of 29:210 Triquinane 6:33,34 angular 13:3-25 diterpenes 13:3-52 linear 13:34-56 precapnelladiene from 6:33,34 sesquiterpenes 13:3-52 sesterterpenes 13:3-52 synthesis of 6:33,34;13:3-52 Triquinane derivatives 7:216 Triquinane terpenes 10:426-428 Claisen rearrangement by 10:426-428 synthesis of 10:426-428 Triquinanes 3:5-48 angular 3:5-7 linear 3:5 synthesis of 3:5-48 Tris (4,5-dichlorophthalimido) trityl bromide (CPTrBr) 14:288 Trisubstituted olefins 4:565 synthesis of 4:565 Triterpenes 27:702 from olive oil 27:702 Triterpenoids 22:97 biosynthesis of 22:97 Triton B 6:320-322;12:244 Tritrophic interaction 27:213,214 DIMBoA in 27:213,214 Tritylation 6:282,284,292,293 Trityl-cyanoethylidene condensation 14:219-226 polysaccharides by 14:228 Tritylperchlorate as catalyst 4:236 Tropolones 1:340 synthesis of 1:340 Tropone 1:549,554-573;10:178;13:624 1,8-addition of lithio tert butyl acetate 1:554 addition to enolates 1:554,555 as diene in [4rt + 2rt] cycloadditions 1:566,571
cis-hydroazulene from 12:251 diazoketone insertion 1:555 for perhydroazulene synthesis of 1:549-556 iron tricarbonyl complexes 1:572 organometallic derivatives of 1:572,573 photochemical electrocyclic closure 1:549 vinyl sulfide cycloaddition 1:567 Trost cyclization 16:423 of allylic acetate 16:423 TTN (thallium nitrate oxidation) 10:631-635,637,638,640,641,644647,653,654,661,662,666,667 Two-stage coupling process (tandem process) 12:35-62 Tyrosine 27:751 iodination of 27:751
Uang synthesis 12:26,27 of avermectin oxahydrindene subunit 12:26,27 of (7-hydroxystaurospermines) 12:26,27 Ueno method 10:322,323 reduction by 10:322,323 Ugi reaction 12:114-138;26:1221 Ullmann biaryl synthesis 20:294-301 Ullmann diarylether synthesis 20:307310 Ullmann macrocyclization 20:308 Ulmann reaction 10:629-631,641,644, 646-653,655,661,667;13:353,354, 364 ;20:294,296,297 ;24:779,780 intramolecular 10:640 Ulosonic acid 30:422,432,433,438 acylation reactions for 30:438 chemical synthesis of 30:432 strategies towards 30:438 synthesis of 30:422 treatment of enolpyruvate 30:432 Ulosonic acid synthesis 30:451-458 alternative approach to 30:452 from glycals 30:453-458 from pyranoses 30:451-453
998
2-Ulosonic ester halides 30:467 glycosylation reactions of 30:467 Umpolung 10:160,167 Umpolung-Michael-Addition 8:46 Uncatalyzed thermal cycloaddition reaction 12:425 Unnatural enantiomer 27:346 Unnatural sialic acid analogues 30:428 synthesis of 30:428 Unnatural ulosonic acid analogues 30:460 synthesis of 30:460 2,3-Unsaturated 1-thioglycosides 8:343 synthesis of 8:343 r acetal 14:502 cyclic enones with 14:502 from dialkyl tartrates 14:489-491 photocycloaddition of 14:502 Simmons-Smith reaction of 14:489-491 Unsaturated acetals 14:490 cyclopropanation of 14:490 from (-)-(2S,3S)- 1,4dibenzyloxy-2,3-butanediol 14:490 2,3-Unsaturated allyl glycoside 10:420 preparation of 10:420 Unsaturated amides 24:683-738 Unsaturated anacardic acids 30:143 synthesis of 30:143 A~7-Unsaturated brassinosteroids 18:515-520 synthesis of 18:515-520 c~,13-Unsaturated butyrolactones 11:453 Unsaturated C-18 fatty acids 1:528-533 Unsaturated carbapyranoses 29:475 preparation of 29:475 synthesis by Arjona 29:477 Unsaturated carbapyranoses synthesis 29:475 by Arjona 29:475 cz,13-Unsaturated carbonyl compounds 4:46 oxidation of 4:46 2,3-Unsaturated C-glycofuranosyl 10:341
by Claisen reaction 10:341 from glycal 10:341 Unsaturated C-glycopyranoside 10:345 from pyranoid glycals 10:345 synthesis of 10:345 2,3-Unsaturated C-glycoside 10:346, 349,350 from Claisen rearrangement 10:338 from lithioglycal 10:312 from peracetylated glycals 10:350 regioselectivity of 10:350 stereoselectivity of 10:350 synthesis of 10:350 1,2-Unsaturated C-glycoside 10:349 Unsaturated C-glycoside 10:354,355 alkylation with dibenzylidene acetal bis (diphenylphosphino) ethane 10:343 alkylation with trifluoroacetate ester 10:343 by palladium (0)- 10:354,355 [3-dicarbonyl C-glycoside 10:348 from glycosyl fluoride 10:368 from peracetylated glycols 10:343 2,3-Unsaturated C-nucleoside 10:341, 342 by reaction of furanose-glycals 10:341 synthesis of 10:341 with pyrimidine-mercury/ palladium acetate 10:341 Unsaturated epoxy hydroxy acids 27:81,82 by nonenzymic induced oxidation of linoleic acid 27:81 (E)-~,~-Unsaturated ester 13:89 5,6-Unsaturated hexopyranosyltheophylline synthesis of 4:237 ~,[3-Unsaturated imide 12:162 asymmetric aldol reaction of 12:162 4-unsubstituted ~-lactam from 12:162
999 (z,13-Unsaturated ketone 4:129 in Luche-type reduction 4:130 reduction of 4:382,383 c~,13-Unsaturated ketone 12:46 JH-NMR spectrum of 12:46 NOE experiments of 12:46 stereochemistry of 12:46 ~,13-Unsaturated ketones 14:438,753 with 2-methyl-6-vinylpyridine 14:438 c~,[3-Unsaturated ketones 3:126,127, 129;6:339,340 reaction with silyl enol ethers 3:126,127,129 synthesis of 6:339,340 Unsaturated ketonucleosides 4:248,253 synthesis of 4:248,253 tumor inhibition by 4:253 A-8,9-Unsaturated lactol 4:420,421 in endoperoxide rearrangement 4:420,421 Z-[3,y-Unsaturated macrolide 8:232 synthesis of 8:232 ~x,13-Unsaturated methoxymethylester 10:412 fragmentation-recombination of 10:412 ~x,lg-Unsaturated nitroolefins 14:636638 2,3-Unsaturated nucleosides 4:223 1,3-intramolecular shift of 4:223 2-Unsaturated nucleosides 4:225 Unsaturated nucleosides 4:235-237 synthesis of 4:235-237 Unsaturated O-glycosides 10:354,355 c~,13-Unsaturated orthoesters 3:146-149 Michael acceptors 3:146-149 A4-Unsaturated oxepene 10:221 A4-Unsaturated oxocenes 10:223 2,3-Unsaturated pentose 10:425 from D-xylal 10:425 Unsubstituted 2-oxazolidone derivative 12:164,166 low l-selectivity of 12:166 with 4-acetoxy 13-1actam 12:164,166 4-Unsubstituted 13-1actam 12:162 4-acetoxy 13-1actam from 12:162
by asymmetric aldol reaction 12:162 by asymmetric hydrogenation 12:162 of [3-keto amide 12:162 of cz,lg-unsaturated imide 12:162 oxidation of 12:162 with peracids 12:162 Unsymmetrical chiral biaryls 20:410 Unsymmetrical onoceranoid triterpene 1:543 synthesis of 1:543 Unsymmetrical pyrazines 18:887-892 (_+)-Upial 6:65,66 from Dysideafragilis 6:65 synthesis of 6:65,66 Urethane 14:566,567 cyclization of 14:566,567 Uridine diphosphate Nacetylglucosamine 1:399 Uridine diphosphate-galactose (UDPgal) 10:468 synthesis of 10:468 Uronolactones 14:192 Ursolic acid 29:575 ursolic acid methyl ester (ursene triterpene) synthesis from 29:575 Ursolic acid methyl ester (ursene triterpene) synthesis 29:575 from ursolic acid 29:575 Urushiol 30:146 ozonisation of 30:146 Urushiols (catechols) 9:318,325,328, 329,331,334,338,352-354,356,358360,364 Validamine synthesis 29:481 by Kameda 29:481 by Yoshikawa 29:481 Valienamines synthesis 29:486 by Bianco 29:487 by Park and Danishefsky 29:486 Valiolamine synthesis 29:485 by Ikegami 29:485 by Shing and Wang 29:485
1000 starting from tetra-O-benzylgluconolactone 29:485 Van Tamelen 29:203 triptolide synthesis by 29:203 VandeWalle approach 6:16 in 13-dictyopterol synthesis 6:16 in dictyopterone synthesis 6:16 Vedejs reagent 11:80,81 Vicinal oxyamination reaction 11:61 1,2,3-Vicinal tricarbonyl unit 8:261-274 synthesis of 8:261-274 Vicinal tricarbonyls 8:261-274 Vilsmeier formylation 1:507,508; 18:233 Vilsmeier reaction 6:322 Vilsmeier's reagent 9:422-424 Vinamidine 2:389,390,398 Vinblastine 2:370,372,287,389,390; 4:29;8:283 ;12:179;13:633 ;14:805884 ;19:748 ;20:458 3'-oxovinblastine from 14:813 anticancer activity of 14:805 Atta-ur-Rahman's synthesis of 14:850-859 biosynthesis of 4:31 Buchi's synthesis of 14:868,869 deacetylvindoline from 14:862,863 first synthesis of 4:32 from anhydrovinblastine 14:820,821,871 from catharanthine 14:854-858 from C a t h a r a n t h u s r o s e u s 8:283;14:805 from leurosine 14:860 Gorman's synthesis of 14:862864 Kuehne's synthesis of 14:831849 Kutney's synthesis of 14:806821 Magnus's synthesis of 14:821830 Potier's synthesis of 14:869-873 Schill's synthesis of 14:861,862 synthesis of 5:185-187 synthetic approaches to 14:805884 Takano's synthesis of 14:865-
867 velbanamine from 14:862,863 Vincristine 2:390,398;9:387;11:5, 12:396;13:633 ;20:458 ;27:778 anticancer activity of 14:805 oxidation of 27:778 Vinyl acetate 1:562,563 reaction with methyllithium 1:562,563 Vinyl azides 1:165 preparation of 1:165 Vinyl carbanions 11:440,441 nucleophilic addition with 11:440,441 Vinyl carbene 3:27 Vinyl cuprate addition 3:189,190, 195,196 Vinyl ether 14:487,488 from (3S,5S)-2,6-dimethyl-3,5heptanediol 14:487,488 from (2R,4R)-2,4-pentanediol 14:487,488 Vinyl iodide 12:48-53 from D-glucose 12:37,38 from 1,2,5,6-Di-Oisopropylidene D-glucose 12:41 from D-ribose 12:50 (Z)-Vinyl iodide 30:20 oxidation of 30:20 condensation of 30:20 Vinyl iodide 30:8 palladium-catalyzed coupling reaction of 30:8 Vinyl palladation 16:371 of 4-cyclopentene- 1,3-diols 16:371 Vinyl radical cyclization 12:24 Vinyl stannane 1:490 synthesis of 1:490 from tributyltin/acetylene 1:490 Vinyl sulfoxides 10:673-676 cyclization of 10:673-676 Vinyl sulfoximines 10:679 cyclization of 10:679 Vinyl tricarbonyl hydrate 8:267-272 Vinylacetyl chloride 14:453,454 condensation of 14:453,454 with 9-chloro- 1-p-menthene 14:453,454
1001 Vinylallenes 4:522 sigmatropic rearrangement 4:522 Vinylation 6:86,87 in 7,20-diisocyanoadociane synthesis 6:86,87 in 14-epi-upial synthesis 6:67,68 of olefins 16:416 Vinylaziridination 3:55 [2+3] 3:55 [4+!] 3:55 Vinylaziridine 3:50 cleavage of 3:50 Vinylcyclobutane 3:465,466 rearrangement of 3:465,466 Vinylcyclopropane isomerization 3:15 Vinylcyclopropane-cyclopentene 3:38,44,47 rearrangement 3:38,44,47 Vinylcyclopropanes 3:38,44,47 from 1,4-dienes 3:38,44,47 pyrolysis of 3:34 via allylic SN 2 process 3:47 Vinylcyclopropylcarbene 14:627 Vinylic anions 4:497 inversion of 4:497 Vinylic ethers 4:116 hydroboration of 4:116 Vinylic sulfoxides 4:501,502 for synthesis of esterone 4:501,502 for synthesis of vitamin E 4:494501 Vinylketene acetals 14:503,504 asymmetric Diels-Alder reaction of 14:503,504 Vinylnitrene cyclization 1:178-180 Vinylogous amide susbtrates 18:376, 386 Vinylogous carbamate substrates 18:344,377 Vinylogous urea substrates 18:363 Vinyloxetane 10:588,589 Vinyloxiranes 3:55-58 synthesis of dihydrofurans 3:5558 Vinyloxyborane-imine reaction 4:465, 466 carbapenem precursors by 4:469 stereochemistry of 4:467,468
Vinylpicoline 14:437,438 bis-annelating agent 14:437,438 Vinylpyridine 14:438 Vinylsilane 8:242 A1C13 catalyzed Friedel-Crafts acylation of 8:242 synthesis of 8:242 Vinylsilane-medicated bicyclization 13:615 Violaxanthin 20:575,727 Viologen oxidoreductase 20:840,858 Viral DNA polymers 30:395 phosphorylation of 30:395 Vitamin A synthesis 28:71 by Baadische Anilin 28:71 by Hoffmann-LaRoche 28:71 by Rhone-Poulenc 28:71 by Soda Fabrik 28:71 Vitamin D analogues 30:483,484, 485,489 synthesis of 30:489 Vitamin D analogues synthesis 30:485494 Vitamin D derivative 30:489,491 synthesis of 30:491 Vitamin D2 30:484,490 synthesis of 30:490 Vitamin D 3 30:490,493 synthesis of 30:490,493 Vitamin D4 30:485,490 synthesis of 30:490 Vitamin D5 30:490 synthesis of 30:490 Vitamin D 7 30:490 synthesis of 30:490 VO-(acac)2-TBHP 10:39,40 epoxidation with 10:39,40 ofallylic alcohols 10:39,40 Volatile components 27:700 of olive oil 27:700 Volucrisporin 29:295 biosynthesis of 29:295 Von Braun degradation 18:51 Wacker oxidation 10:308,309,316; 13:494;14:560,561,584;16:481; 18:273,283,633 ;19:29 in (___)-brasilenol synthesis 6:7
1002
Wacker process 11:238,241,246,16:85 Wadsworth-Emmons chain extension 13:596 Wadsworth-Emmons condensation 1:52,60;13:573 Wadsworth-Emmons cyclization 23:493 Wadsworth-Emmons reaction 1:176, 177;7:480;11:89;12:328;16:349; 18:897;24:720 intramolecular 11:108 Wadsworth-Emmons-Horner reduction 20:450 Wadsworth-Horner-Emmons olefination 26:1230 Wadsworth-Horner-Emmons reaction 1:401,402 Wagner-Meerwein rearrangement 4:38, 39,626- 628,633,634,637,643 ;6:52, 149,181 ;12:37,131,147,236,248,245, 356,363-368 ;24:30-32 of end-6-silyloxy-isoborneol 16:147 1,2-Wagner-Meerwein shift 18:882 Wallenberg's procedure 6:298,299 warburganal 6:108 Warburganal 24:175-182 synthesis of 24:175-182 Warren procedure 3:257 Wartski imine Diels-Alder reaction 16:458 Watt synthesis 14:678-681 of taxodione 14:678-681 Weiler's reaction 11:115 Weinerb reaction 26:1239,1243 Weinreb's amide 30:473 synthesis of 30:473 Weiss-Cook condensation 3:23,24 Weiss reaction 18:286 Welch procedure 10:308,309 demethoxycarbonylation by 10:308,309 Welch synthesis 6:17 of isozonarol 6:17 of zonarol 6:17 Wender synthesis 13:445,446 of 7-methoxymitosene 13:445,446 Wender's [4+4] cycloaddition strategy 12:189
Wenkert's enamine 1:113;14:727 synthesis of 14:727 Wenkert-type enamine 8:284,285 Wessley-Moser rearrangement 2:133,665 Western blotting analysis 15:449 Wharton reaction 10:47 Wharton rearrangement 10:36,37 Whistler method 6:367 White synthesis 12:15,27,28 of avermectin B la aglycone 12:15,27,28 Wieland-Gumlich aldehyde 9:183 Wieland-Gumlich diol 1:38,39 Wieland-Miescher ketone 6:18,19 endesmanes from 6:18,19 endesmanolides from 6:18 synthesis of 6:18,19 (+)-Wieland-Miescher ketone 10:409 Wieland-Miescher ketone 11:16-18,50, 51,53;17:608,29 absolute configuration of 17:53 Wierenga intramolecular alkylative closure 3:325,326 Wilcox and Gaudino 29:460,461 carbaketofuranose synthesis by 460,461 Wildman procedure 4:19,22 Wilkinson catalyst 6:10,11;9:459,474; 10:39;11:354,363 ;12:8,35,37,38,40, 50,267,311 ;13:564;18:207;19:500 for decarbonylation 16:340, 345,350 Wilkinson complex 11:363 decarbonylation with 11:363 Willgerodt reaction 14:681,682 Williams approach 12:28-30 for avermectin oxahydrindene subunit 12:28-30 Williams enantioselective synthesis 6:15 of (-)-zonarene 6:15 Williamson ether synthesis 6:386 Wilson synthesis 10:48 Winstein spirocyclization 3:325 Witkop photocyclization 1:52 Wittig condensation 3:462;12:281; 13:620;14:112;19:59;20:582
1003 of olefin 5:708 in (k)-sinularene synthesis 6:85 Wittig coupling 10:9,15;13:617 i n 7,20-diisocyanoadociane synthesis 6:86,87 Wittig cyclopropanation 21:397 Wittig homologation 3:268,269;11:100, 101;18:196,216;21:397 Wittig methodology 21:39 I Wittig methylenation 6: 185,165; 19:42;18: I77 Wittig olefin 30:443 formation of 30:443 Wittig olefination 1:460,46 1,473,487, 488;4:252,123,I63,I64,I69,I76,279, 280,285,286;8:4 13;10:429;12:327, 330;13:604;14: 129, I32,460,46 1; 16:377,378,388,484;18:8;19:22,137; 21 :388,397,4 15,428,439,440,445; 24:8;26: 1234 for fused lactone nucleoside synthesis 4:254 in (+)-precapnelladiene synthesis 6:39 in (+)-stoechospermol synthesis 6:39 in nakafuran-9 synthesis 6:70 i n nine-carbon sugars synthesis 4: 180 of amino aldehyde 16:490 of D-galacto-hexodialdopyranose 4: 163,164 of D-l y xo-pentodialdofuranosidc 4: 176 of heptodialdopyranose derivative 4: 180, I8 1 of hexodialdopyranoside derivative 4: I69 of pentodialdofuranose 4: 190 of r-hutyl 2-C-methyl-2,3,4,7tetradeoxy hept-6-ulopyranoside 10:4 I4 with N-pentylidene triphenylphosphorane 5:822 Z-selective 4: I25 Wittig reaction 1:22 1,399,400,447,448, 53 I ,533,535,538;3:258,288,488; 4: 126,i SO, 175,202,553-578;5:828; 6: 16- I9,2 I ,6 I ,68,125,157, I 58,225,
226,269,279,28 I,285,286,301,302, 425,558,559;8:46,146,I47,I6 I - 164, 223,224;9:35 I ,352,354,356,358,360, 362;10:48,55,68,I66,308,309,389 3923 10;11:367;12:3I9,321,350,488; 13:32,35,37,125,141,175,200,208, 482,508,594;16:4,39,60,85,248,352, 702;18: 178,233,234,255,256,288, 297,618;19: 10,20,43,72,267,367, 373,396,495;20:563,566,567,57I , 572,578,584,586-592,594,599,60I , 602,606,759;21:380,4I2,446;24: 7,188,190,719,720;26:65,66,70,72, 73,75,8 133-9I ;30:146,442,443 in 3-deoxy-2-ulosonic acids 30:443 C-glycosides by 3:218-220 hydroxyl directed 1:406,407 intramolecular 4573,575 of iodide 14:556,557 o f aldehyde 8: 163,164,223, 224,19:495 of glutarimide 14:560 of ketone 8:I62 01' pyrrolidine derivative 14:556,557 of hromodecanal 26:83 of 8-formyloct-5-enoate 26:86 of (E)-S-methyltetradec-4-enal 26:72 o f 26: 12-hydroxy-2-methyldodecanal 26:70 of 6-methyl-2-heptanone 26:65 of7-methyl-2-heptanone 26:65 of 5-methyl-2-hexanone 26:66 of 5-pentadecenal 26:75 stereoselective 12: 12 stereoselectivity 4: 175 unstabil ized 1:406,407 with Corey reagent 19:452 with ethyl (triphenylphosphoranylidene) acetate 14:553,554 with formyulmethylene triphenyl phosphorane 1535,536,538 with glutaric dialdehyde 14560 with heptylidene triphenylphosphorane 5:828 with hexylidenetriphcnyl-
1004
phosphorane 19:495 with sugars 3:218-220 Wittig reagent 4:126;158;6:71;10:63; 11:72,78;16:64;19:57;30:15 conformational models 3:248, 252 in lactone synthesis 3:252,255 in synthesis of higher-carbon sugars 4:158 of secondary allylic ethers 3:249 of tertiary allylic ethers 3:251 of zirconium enolates 3:241 of a-allyloxy anions 3:248-250 stereochemical induction 3:248252 Wittig reduction 21:397 [2,3]Wittig ring contraction 10:34-42 by chiral amide bases 10:31-33 [2,3]-Wittig sigmatropic rearrangement 10:61,62 Wittig ylide 6:181,183 Wittig-Horner chain extension 21:390 Wittig-Horner condensation 11:159,298 Wittig-Horner cyclization 12:292 intramolecular 12:292 Wittig-Horner homologation 18:333 Wittig-Horner olefination 11:431-435 Wittig-Horner reaction 4:602,603; 7:484 ;10:673 ;12:324,462;18:247, 623 ;19:256;29:427 marine alkaloids synthesis by 29:427 Wittig-Horner reagent 19:84 Wittig-methylenation 10:413 of L-mannose 10:413 Wittig-type condensation 21:409 Wittig-type methodology 21:383 Witting olefination 30:443 of sugar aldehydes 30:443 Wolff rearrangement 19:18;21:438 of diazoketone 10:593-595 oxetane ring formation 10:592,593 Wolff ring contraction 6:178,179 Wolff-Kishner cyclization 1:58 Wolff-Kishner reaction 14:684 Huang-Minlon modification of 14:684
Wolff-Kishner reduction 2:235;4:416; 6:6,17,509;8:164,165;13:6,11,12, 21-23,403 ;14:277,278,359,417,419, 452,453,728;15:231 ;18:35;19:135; 24:175,176-179,199 Wolf-Kischner reduction 21:707 Woodchuck hepatitis virus 20:535 Woodward reaction 19:363 Woodward reagent K 6:238,247,405 Woodward-Hofmann rule 2:128;3:401 Wortmannin 6:219,220 Wulff 29:379 allocolchicinoids total synthesis by 29:379 Wurtz coupling 9:344 Xanthurenic acid 26:991 microbial transformation of 26:991 Xenobiotics 27:749 oxidation of 27:749 Xylerithrin 29:298 biosynthesis of 29:298 Xylerythrins 29:299 synthesis of 29:299 Xylitol pentaacetate 4:509 synthesis of 4:509 D-Xylo-hexofuranose 6:365,367,372 Cs-P bond analogs of 6:365,367, 372 Xylosides 8:362 synthesis of 8:362 Xylosyl chlorides 8:359-362 Yamada's synthesis 12:203 Yamaguchi conditions 26:1229,1230 of 4-AboA 27:193,203,204,225 Yamaguchi method 11:154,157,158 Yamaguchi reagent 11:157 Yamamoto condensation 12:24 of propargylic titanium reagent 12:2 regioselective 12:24 stereoselective 12:24 Yang et al. 29:210 triptolide synthesis by 29:210
1005
(+)-Yatein 29:388 steganes synthesis of 29:388 Yeast reduction 1:482;13:560 Yeasts 1:689 for asymmetric reduction 1:689 Yoshikawa 29:481 validamine synthesis by 29:481 Yu-Lin-Wu synthesis 6:14 of (__)-polygodial 6:14 of (-)-polygodial 6:14
(Z)-zinc (II) enolate 12:166 Zaitev reaction 1:318,517,518 Zanardi and co-workers 29:473 carbaaldopyranoses synthesis by 29:473 Z-Diene 16:4 Zeaxanthin 27:321 in biosynthesis 27:321 Zeaxanthin disulphate 30:528 synthesis of 30:528 Zemple'n conditions 6:409 Zemplen de-O-acetylation 12:348 Zemple'n O-deacetylation 6:412 Zemple'n reaction 6:411 Zemplen transesterification method 21:163 Z-Enediones 16:648 Z-Enolate 16:661 Z-homoallylalcohol 30:41 Lindlar's catalyst 30:41 Ziegler/Brown/Robin 29:391 steganes synthesis by 29:391 Zimmerman-Traxler transition state 4:445 Zinc (II) chloride 12:172,173 1,4-dehydro-13-1actam from 12:172,173 with 4-acetoxy-13-1actam 12:172,173 Zinc (II) iodide 12:164 Zinc borohydride 1:261;4:348 reduction with 1:261;4:348 Zinc bound alkoxide 17:481 Zinc clathridine 17:18 Zinc mediated coupling 1:264,265
Zinc-copper couple 4:424 in deoxygenation 4:424 in reductive elimination 4:165 Zinc-dust 12:166 in deoxygenation 4:424 Zincke's salt 19:38 Zirconium (IV) enolate 12:168 Zirconium derivatives 9:453 as fluorescence-inducing reagent 9:453 Zirconium enolate 13:506 ofphenylthio ester 13:506 Zirconium enolates 3:249 [2,3]-Wittig rearrangement of 3:249 Z-Isomers 30:441 by transesterification 30:441 Zwitterionic aza-Claisen rearrangement 16:466
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1007
CUMULATIVE PHARMACOLOGICAL ACTIVITY INDEX VOLUMES 1-30 A~ adenosine agonists 25:265 somatostain as 25:265 opiates as 25:265 A2-agonists 25:265 A-549 (human lung adenocarcinoma) 30:588 activity of (-)-deoxypodophyllotoxin against 30:588 activity of (-)-yatein against 30:588 1AA oxidation 25:657 inhibitor of 25:657 AADC 30:380 activity of 30:380 deficiency of 30:380 in abnormal sleeping 30:380 in eye movement abnormalities 30:380 in feeding difficulties with esophagea reflux 30:380 Abdominal constriction test 30:207 activity of (-)-menthol in 30:207 Abdominal pain 30:203,205 use of ginseng root in 30:203 use of Psycotria colorata in 30:205 19(4--+3)-Abeo-8 c~,13(S)-epoxylabda4(18), 14-diene 29:102 activity in EBV bioassay system 29:102 19-nor-Abieta-4( 18),8,11,13-tetraen-7one 29:100 activity in EBV assay system 29:100 Abieta-8,11,13-trien-7-one 29:99 activity in EBV assay system 29:99 18-nor-Abieta-8,11,13-triene-4c~,7a, 15triol 29:99 activity in EBV assay system 29:99 Abieta-8,11,13-triene-7ot, 15,18-triol 29:99 activity in EBV assay system 29:99
Abieta-8,11,13-triene-7o~,l 5,18-triol 7acetate 29:99 activity in EBV assay system 29:99 Abietic acid 29:99 activity in TPA assay system 29:99 activity in CRG assay system 29:99 Abiotic stress 23:741 Abri Herba 25:99 antihepatotoxic effect of Ogs from 25:99 Abrus precatorius L. 22:510 for epilepsy 22:510 Abscisic acid 27:331,352 activity of 27:331 biological activity of 27:332 Abscisic acid analogs 27:323-329 activity of 27:483 Absinthin (guaine sesquiterpene dimer) 29:574 effects on HIV- 1 protease 29:574 Absintholide (guaine sesquiterpene dimer) 29:574 effects on HIV- 1 protease 29:574 (2S)-Abyssinone II 28:17 as aromatase inhibitor 28:17 Acacetin (5,7-dihydroxy-4'-methoxyflavone) 29:571 inhibition of HIV- 1 protease 29:571 Acalyphafi'uticosa sk. 22:510 for epilepsy 22:510 Acanthodendrilla sp. 28:702 antifungal activity of 28:702 Acanthoic acid 29:103 activity in TNF~ bioassay system 29:103 Acanthophyllum squarrosum 26:55 immunomodulatory effect of 26:55
1008
Acarbose 13:3 as cx-amylase inhibitor 13:3 as ot-glucosidase inhibitors 7:47 as antihyperglycemic drug 10:505 as antihyperlipoproteinaemic drug 10:505 Acaricidal activities 24:799;28:403,406, 412,422 against Dermatophagoides pteronyssinus 28:422 against Psoroptes cuniculi 28:412 against Rhipicephalus appendiculatus 28:406 for killing adult ticks 28:403 of caffeine 28:422 ofCuminum cyminum 28:427 of essential oils 28:412,427 of Eucalyptus camaldulensis 28:427 of eugenol 28:403 of extract prepared by microwave assisted process (MAP) 28:427 of Lavandula angustifolia 28:412 oflinalool 28:412 of Margaritaria discoidea 28:406 of Origanum syriacum var. bevanii 28:427 of phenylpropanoid derivatives 28:403 ofPimenta dioica 28:403 of Pimpinella anisum 28:427 of Tanacetum vulgare extracts 28:427 of ~-thujone 28:427 Acaricidal properties 28:400,406 of benzaldehyde 28:406 of carvacrol 28:406 of cedrene 28:406 of cx-cyclocitral 28:406 of ~-cyclocitral 28:406 of Euphorbia obovalifolia latex 28:400 of Ficus brachypoda latex 28:400
of geraniol 28:406 of (E)-geranylacetone 28:406 of ct-ionone 28:406 of linalool 28:406 of m-cymene 28:406 of methyl salicylate 28:406 of nerol 28:406 of nerolidol 28:406 of nonanal 28:406 of 13-ocimene 28:406 ofphenylacetaldehyde 28:406 of phenylacetonitrile 28:406 of a-terpineol 28:406 Acaricide 28:381,429,435 cross-resistance of 28:429 Acetaminophen 30:192 as analgesic/antipyretic 30:192 (-)-Acetomycin 10:443 antimicrobial activity of 10:443 antitumor activity of 10:444,447 (+)-5-epi-Acetomycin 10:447 antitumor activity of 10:447 2(x-Acetoxy- 14-hydroxy- 15-iso-valeroyloxy-9-oxo-costunolide 29:89 activity in NFkB assay system 29:89 activity in TNF(x assay system 29:89 9cx-Acetoxy-4~, 15-epoxymiller- 1( 10)Zenolide 29:89 activity in NFkB assay system 29:89 3~-Acetoxy-813-isobutyryloxy-reynosin 29:87 activity in Mam-2 assay system 29:87 activity in DIF assay system 29:87 15-Acetoxy-9 ~-hydroxy- 8 [3-methacryloyloxy- 14-oxo-acanthospermolide 29:89 activity in NFkB assay system 29:89 15-Acetoxy-9cx-methacryloyloxy-8 ~hydroxy- 14-oxo-acantho- spermolide 29:89 activity in NFkB assay system 29:89
1009 3-Acetoxycostunolide 29:89 activity in NFkB assay system 29:89 15-Acetoxy-eremantholide B 29:89 activity in NFkB assay system 29:89 activity in TNF~ assay system 29:89 9~-Acetoxy-miller- 1( 10)-Z-enolide 29:89 activity in NFkB assay system 29:89 (+)-Acetoxypinoresinol dimethyl ether 26:241 as PAF-induced inhibitor 26:241 6c~-Acetoxyvouacapan- 17,7[3-1actone 29:103 activity in AOS bioassay system 29:103 Acetyl- 11-keto-[3-boswellic acid (triter-pene) 29:585 effects on LELA 29:585 Acetylcholine 25:516,519,520,527,530, 547 nicotinic receptor for 25:519 vasodilator effect of 25:595 Acetylcholine receptor 18:863 Acetylcholine-gated Na+/K§ 25:527 Acetylcholinesterase inhibitors 21:585 [3-(1-6)-N-Acetylglucosaminyl transferase 10:486 in biosynthesis of I-antigens 10:486 8-Acetylharpagide 29:83 activity in EBV, liver-l, lung-2, skin-1, skin-4 assay systems 29:83 (+)-Acetylphomalactone 19:479 antifungal activity of 19:479 antitumor activity of 19:479 insect antifeedant activity of 19:479 plant growth inhibitory effect of 19:479 ( TR, 8S, 7 ' R, 8 ' R )-( + )-7 '-Acetylp icro-
podophyllin 30:568,593
use of soft agar transformation assay 30:593 4c~-O-Acetyl-pseudoguain-6[3-olide 29:90 activity in TPA assay system 29:90 Ach receptor 21:92,98 AChE activity 21:748 AChE inhibitor 21:749 Aciclovir (9-[2-hydroxyethoxy methyl] guanine) 10:585 antiviral activity of 10:585 Acid-induced abdominal contraction test 30:205 activity of (+)-allomatrine in 30:205 activity of (+)-matrine in 30:205 Aconite 24:898-899 neuromuscular blocking effect of 24:898-899 Aconitine 24:898-900 as anti-inflammatory agent 24:898 as cardiotonic agent 24:898 for relieving muscle pain 24:898 Acorus calamus L. 22:510 for epilepsy 22:510 Acquired immunodeficiency syndrome (AIDS) 23:3;25:734,941,948;30:412 Acridine 25:542 based PKA inhibitor 25:542 Acronycine 13:365-375 antitumor activity of 13:365-375 [~-Actin 30:779 cytokine mRNA expression of 30:779 (+)-Actinobolin 16:3 antineoplastic activity of 16:3 as microbial antitumor antibiotics 16:3 dental cariostatic activity of 16:3 immunosuppressive activity of 16:3 Actinomycin 26:1009 Actinomycin D 24:547 antiviral microbial-derived compound 24:547 Actinomycin D (Dactinomycin) 26:1009
1010
Actinoplanes sp. 25:777 effect on K-cells-IL2-activated killer cells 25:273 Actinoplanic acids 24:428-429 activity against VSV, HSV-1, poliovirus SV, FMDV 24:524 Activators 27:833 from Daphne cannabina 27:833 from Daphne mezereum 27:833 from Thymelaceous plants 27:833 from Wikstroemia indica 27:833 6-Active peptide analogues 30:801 synthesis of 30:801 Activities 22:354;25:257;27:323,331, 333,504,513 for Astragalus spp. 27:483 from Phyllanthus amarus 27:840 of Astragali radix 27:513 of abscisic acid 27:331,352 of abscisic acid analogs 27:323-329 of diarylheptanoids 27:852 of enzymes 27:378 of flavonoids 27:504 of fluorinated probes 27:333 ofhydrolysable tannins 27:840 of labdane 25:257 of monoterpenes 27:384 ofodour substances 27:378 ofphosphorylase kinase 27:852 of protein kinases 27:826 of serine 27:850 of threonine 27:850 of tyrosine 27:850 of xanthine oxidase 22:354 Actomysin ATPase-activating activity 23:193 ofpenaresidin A 23:193 of penaresidin B 23:193 Acute diarrhoeal disease 30:747 Acute gastritis 30:153 Helicobacter pylori as causative agent of 30:153 Acute hepatitis 30:406 chemotherapy of 30:406 Acute leukemia 14:805 in children 14:805
vinblastine for 14:805 vincristine for 14:805 Acute myocardial infarction (AMI) 30:839,844 use of fibrinolytic agent 30:839 Acute pain 30:799 analgesic alkaloid in 30:799 Acute toxicity 27:307 of stevioside 27:307 of steviol 27:307 Acyclic 11-carboxy- 12-nor-transnerolidol 29:87 activity in EBV assay system 29:87 Acyclic cis-nerolidol 29:87 activity in EBV assay system 29:87 Acyclic trans-nerolidol 29:87 activity in EBV assay system 29:87 Acyclovir 24:474,486;25:116;26:226 as anti-viral agent 24:474,486 Acylovir-resistant HSV-1 25:940 Addiction 30:799 by analgesic alkaloid 799 Adenocarcinoma 1:276;26:712 of colon 1:276 Adenocorticorophic hormone(ACTH) 25:265 Adenohypophysical hormones 25:265 Adenosine A1 receptors 25:532 Adenosine receptors 22:25,20 S-Adenosylmethionin-dccarboxylase inhibitor 26:830 Adenylate cyclase activator 25:488 Adenylate cyclase system 25:493 Adenylyl cyclase 25:532 inhibition of 25:532 Adipokinetic hormones 9:487,489 Adipose tissue 30:81 Adipose tissue distribution 26:1130 as syndrome type-lA 26:1130 Adiposin-1 and 2 10:514 inhibitory activity against aamylases 10:514 Adiposins 10:514 antibacterial activity of 10:514 a-glucosidase inhibitors of 10:513
1011 Adjuvant activity 21:646,650;26:55 of Gypsophila 26:55 of Quillaia 26:55 of Saponaria 26:55 Adjuvant arthritis 22:119 Adjuvant induced polyarthritis 25:46 inhibition of 25:46 Adrenaline 30:58 intravenous infusion of 30:58 a2-Adrenergic 25:530 type G-protein-linked receptor 25:530 Adrenergic activity 23:356 of coumarin 23:335,353,356, 357,368,376,393,550,553 Adrenergic agonists 21:109 Adrenergic alkaloids 21:68 Adrenergic antagonists 21:57;25:530 Adrenergic blocker 22:19 ~-Adrenergic blocking agents 14:473 synthesis of 14:473 (z-Adrenergic neurons 21:18 [3-Adrenergic neurons 21:18 ot-Adrenergic receptor 21:18 [3z-Adrenergic receptor 21:51 [3-Adrenergic receptor kinase 21:264 Adrenergic receptors 21:57;22:19; 25:271,530 c~-Adrenergic receptors 21:90 (x2-Adrenergic receptors 21:90 [32-Adrenergic receptors 27:825 [3-Adrenoceptors 22:667 ~-Adrenoceptors 25:30 Adriamycin 14:474 4-demethoxy analogs of 14:474 synthesis of 14:474,475 Adriamycin-resistant P-333 cell 21:264 Aerugidiol 29:90 activity in HPT assay system 29:90 Aethiopinone 29:100 activity in CRG assay system 29:100 ~t-Affinity 30:807 in guinea pig brain membranes 30:807 in rat brain synaptosomes 30:807
8-Affinity 30:807 with deltorphins 30:807 Aflastatin A 28:127,128 as aflatoxin inhibitor 28:128 Aflastatin B 28:127,128 as aflatoxin inhibitor 28:128 Aflatoxin inhibitor 28:128 aflastatin A as 28:127,128 aflastatin B as 28:127 African swine fever virus (ASFV) 30:410,412 effect of marine microalgae on 30:410 in vitro 30:410 transmission of 30:410 African trypanosomiasis (HAT, sleeping sickness) 26:784 Agastanol (diterpene) 29:574 effects on HIV- 1 protease 29:574 Agastaquinone (diterpene) 29:574 effects on HIV-1 protease 29:574 Agelas nakamurai 28:670 antispasmodic activity of 28:670 Na+/K+-transporting adenosine triphosphate (ATP)ase inhibitor from 28:670 Age-related mascular degeneration 30:525 role oflutein in 30:525 role of zeaxanthin in 30:525 Agglutination 30:204 inhibition by hederagenin monodesmosides 30.-204 Agglutination inhibitors 2:308,309 Aggregation 25:358,360 ofheme into hemozoin 25:360 of porphyrin and metalloporphyrin systems 25:358 Aggregation pheromone 1:692 of Gnathotrichus 1:692 Aggreticin 5:597 platelet aggregating inhibitor 5:597 Aging 30:224 role of free radicals in 30:224
1012
Agnuside 29:84 activity in COX assay system 29:84 ~t-Agonist 30:799,801 dermorphins as 30:799 inhibitory effects of 30:801 6-Agonist 30:799,807 deltorphins as 30:799 [LeuS]enkephalin as 30:807 6-Agonist (D-Ala2) deltorphin II 30:801 evaluation of 30:802 Agonist effect 25:533 of oripainine 25:533 ~t-Agonist tetrapeptide 30:813 k-Agonist U-50 30:807 activity in GPI assay 30:807 Agonistic activity 21:68,95 Agonists 21:51 c~2-Agonists 8:396-298 Agropyron repens L. 27:216 allelopathic interaction of 27:21 AIDS 2:421-426;21:297,616,661,665; 22:248;30:226,396 mechanism of action of 30:226 AIDS virus 12:245 AIDS-associated lymphoma 21:138 Ailantinol A 23:317 cytotoxicity of 23:317 Ajoene 28:432 acaricidal activity of 28:432 against Tetranyehus urticae 28:432 anticoagulant properties of 28:432 Akaterpin 28:673 as phosphatidylinositol phospholipase C inhibitor 28:673 Akendo 29:100 activity in TPA bioassay system 29:100 activity in CRG bioassay system 29:100 Alanine transaminase (ALT) 25:475 Alarm pheromone 6:453,454 n-undecane in 6:453,454
Alaternin 30:321 as antioxidant 30:321 Albanin D 28:229 biological activity of 28:229 Albanin F 28:230 biological activity of 28:230 Albanol A 28:17,230 as aromatase inhibitor 28:17 biological activity of 28:230 Albanol B 28:229 biological activity of 28:229 Albizzia harveyi Foum. 22:511 for epilepsy 22:511 Alcohol consumption 30:374 autistic features in 30:374 Alcohol dependence 30:799 Aldose reductase inhibition 6:20;21:593 alkaloids in 21:3,20,109 as medicine 21:109 biorational plant protectants 21:109 by (+)-dysideapalaunic acid 6:20 by ion channels 21:3,20 Aldose reductase inhibitor 22:166; 28:691 from Dictyodendrilla sp. 28:691 Algal and cyanobacterial toxicity 26:376 testing of 26:376 Algicidal activity 26:358 Alginasic 24:995-998 enzymatic activity of 24:995-998 Alkaloid 24:527-533;30:563,596,799 as analgesic 30:799 as antiviral compound 24:527-533 in vivo antimalarial assay 30:596 in vivo intrinsic activity of 30:596 molluscicidal activity of 7:427 Alkenyl phenols 7:427 molluscicidal activity of 7:427 3-Alkyl-5-arylimidazolidinediones 30:198 as CBI cannabinoid receptor 30:198 as pharmacophore 30:198 Alkylresorcinol 30:159,167 as drug 30:159
1013 Allamandicin 16:299 antifungal activity of 16:299 antileukemic activity of 16:299 antimicrobial activity of 16:299 cytotoxic activity of 16:299 Allamdin 16:299 antifungal activity of 16:299 antileukemic activity of 16:299 cytotoxic activity of 16:299 Allelochemical 9:387,21:107 Allelochemical alkaloids 21:103 Allelopathic activities 20:391 ;21:109; 24:845;28:483 of natural podolactones 28:484 of synthetic podolactones 28:484 Allelopathic agent 26:187 Allelopathic interactions 27:214-218 of Agropyron repens L. 27:216 ofAvenafatua L. 27:215 of Avena sativa 27:216 ofAvena strigosa L. 27:215 of Lactuca sativa L. 27:215 of Secale cereale L. 27:125,216 of Taraxacum officinale Wigg. 27:215 of Triticum aestivum L. 27:215 of Zea mays 27:215 Allelopathy 24:867;25:658 bioassay of 24:867 Allergenic dermatitis 2:277,280-281 Allergenic property 30:157 of anacardic acid 30:157 Allergenicity problems 27:315 of Stevia 27:315 of stevioside 27:315 Allergen-specifc IgE 30:773 Allergen-specific Th2 response 30:776 Allergic encephalomyelitis 21:135 Allergic inflammation 30:55 role of natural products in 30:55 Allergic inflammatory disease 30:69 use of Scutellaria baicalensis in 30:69 Allergic reactions 30:773 Allergy inhibitors 5:759 Allergy processes 30:225 role of leukotrienes in 30:225 Allium cepa L. 22:511 for epilepsy 22:511
Allocolchicinoid synthesis 29:364 for biological screening 29:366 Allocolchicinoids 29:356 effects on tumour vasculature 29:366 in clinical trials 29:366 (+)-Allomatrine 30:205 activation of kappa-opioid receptors by 30:205 activity in acid-induced abdominal contraction test 30:205 antinociceptive effect of 30:205 SAR of 30:205 Allyl formate-induced liver injury 25:466 Aloe arborescens 30:309 against colon carcinogenesis 30:309 Aloe barbadensis 30:341,412 against coxsackie virus 30:412 Aloe spp. 30:338 in acute liver injury 30:338 Aloe vera L. 22:511 for epilepsy 22:511 Alphitolic acid 28:62 anti-microbial activity of 28:62 Alstoniascholaris R. Br. 22:512 for epilepsy 22:512 Alstonia venenata R. Br. 22:512 for epilepsy 22:519 Alternosides I-V 27:41,44,45 as sweetness inhibitors 27:41 Altholactone 19:498 biological activity of 19:498 Alvaxanthone 28:229 biological activity of 28:229 Alycoprotein-rich substance (CVS) 776 against experimental metastasis 30:776 antitumor effect of 30:776 Alzheimer dementia progression 21:585 Alzheimer's diseases 14:637;21:748, 749;22:343 ;30:504 (-)-physostigmine for 14:637 Alzheimer's disease therapy 25:530, 536,710
1014
Amantadine 27:108 for treatment of influenza A 27:108 Amariin (hydrolysable tannin) 29:572 effects on HIV- 1 protease 29:572 Amastatin [(2S,3R)-3-amino-2-hydroxy5-methylhexanoyl-L-valyl-L-valylL-aspartic acid)] 12:434 leucine aminopeptidase inhibitor of 12:434 Amblyomma variegatum 28:395 repellent properties of 28:395 Ambrosanolide 29:90 activity in EPP assay system 29:90 Amebicidal activity 6:485 of emetine 6:485 of 1,2-secoemetine derivatives 6:485 Amentoflavone (3',8"-biapigenin) (biflavone) 29:578 effects on ACE 29:578 American trypanosomiasis (Chagas disease) 26:784,798 Ames test 27:303,304 Amidiol (taraxast-20(30)-ene-3[3,16[3diol) (triterpene) 29:585 against bacterial diseases of rice plants 29:480 as neuraminidase inhibitors 29:464 biological profile of 29:480 effects on CHY 29:585 effects on glycosidase enzyme 29:480 in structure-based drug discovery 29:464 Aminoalkylindoles 30:196,197,198 as cannabinoid receptors ligands 30:197 T-Aminobutyric acid (GABA) 30:782, 784 as inhibitory neurotransmitter 30:782 effects on blood pressure 30:784 effects of 30:784 Aminocyclitol inhibitors 10:517-524
3-Aminoflavones 27:926 for cytotoxicity 27:926 Aminoglycopyranoses 7:47 [3-glactosidase inhibition with 7:47 2-Aminooxetanocin A 10:619,620 antiviral activity of 10:619,620 Aminoquinone 5:437 immunosuppressive effect of 5:437 Aminotransferase activity 19:650 (3R)-y-Amino-[3-hydroxybutyric acid 12:434 biological activity of 12:434 as central inhibitory transmitter 12:434 Amoebicidal activity 26:458 Amoebicides 7:398 AMOX 28:224 anti-microbial activity of 28:224 Amoxicillin 25:617;26:366 Amphetamine 25:537 as immunosuppressive drug 25:537 Amphibian alkaloids 29:433 pharmacological activity of 29:433 Amphidinolide M 19:566 cytotoxicity of 19:566 Amphidinolide Q 19:560 cytotoxicity of 19:560 Amphotericin B 2:421,422,446; 4:513-520;6:261-306;10:150;17:245; 26:794,795 Ampicillin 25:258 AMPK phosphorylates 25:525 Amygdala 30:375,376,379 effect on dorsal raphe serotonin (5-HT) neurons 30:376 Amylase 24:995-998 enzymatic activity of 24:995-998 c~-Amylase inhibitor 13:189 acarbose as 13:189 Amylostatins GXGGG 10:509 inhibitory activity of 10:509 Amylostatins GXG 10:509 inhibitory activity of 10:509
1015
Amylostatins GXGG 10:509 inhibitory activity of 10:509 Amylostatins XG 10:509 inhibitory activity of 10:509 synthesis of 10:507-511 Amylostatins XGG 10:509 inhibitory activity of 10:509 Amylostatins XGGG 10:509 inhibitory activity of 10:509 ~-Amyrenol 29:585 effect on CHY 29:585 effects on HIV- 1 protease 29:574 effects on collagenase 29:583 ~-Amyrin 29:585 effect on CHY 29:585 effects on HIV- 1 protease 29:574 effects on collagenase 29:583 Amyrin 30:206 use in inflammatory skin conditions 30:206 c~-Amyrin (c~-amyrenol; viminalol) (ursane triterpene) 29:574,583 effects on collagenase 29:583 effects on HIV- 1 protease 29:574 [3-Amyrin (ursene triterpene) 29:574 effects on HIV- 1 protease 29:574 c~-Amyrin linoleate 29:583 effects on collagenase 29:583 c~-Amyrin linoleate (c~-amyrin cis9,cis- 12-octadecadienoic acid acid ester) 29:585 effects on CHY 29:585 c~-Amyrin palmitate (c~-amyrin hexadecanoic acid ester) 29:583 effects on collagenase 29:583 Anabsin (guaine sesquiterpene dimer) 29:574 effects on HIV- 1 protease 29:574 Anabsinthin (guaine sesquiterpene dimer) 29:574 effects on HIV- 1 protease 29:574 Anaesthetic activity 21:378
Anagallis arvensis L. 22:512 for epilepsy 22:512 Analeptic 30:72 Angelica keiskei use as 30:72 Analgesia 30:200,799,800,801 by 8-opioid receptor activation 30:801 by opioid 30:799 in mice 30:800 role of delta opioid receptor in 30:799 role of mu-opioid receptors in 30:799 Analgesic 17:633;30:193,194,204,799 alkaloid 30:799 use of Cannabis sativa L. as 30:194 use of Di~psacus a~per as 30:204 use of Papaver somniferum as 30:193 Analgesic action 30:193 of olvanil 30:193 of ricinoleiic acid 30:193 of triphenyl phenol scutigeral 30:193 Analgesic activity 21:595,673;23:153, 180;26:32,56;30:195,198-201,817 ofbarbatosides A and B 26:56 of cembranes 23:180 ofdianosides A-1 26:32 of DPDPE 30:817 of enkephalyn 30:817 of kallilolides 23:180 of kallilolides 23:180 of opioids 30:198-201 ofpseudopterolides 23:180 of pseudopterosins 23:153, 158,180 of secopseudopterosins 23:180 structure-activity relationships (SAR) 30:198 Analgesic alkaloid 30:799 addiction due to 30:799 for acute pain 30:799 gastrointestinal depression due to 30:799 respiratory depression due to 30:799
1016
side effects of 30:799 tolerance due to 30:799 Analgesic characteristics 30:817 Analgesic drug 30:191,192,203 development of 30:192,203 use of 30:191 Analgesic effects 26:401,403,404,406, 416,418;30:205,208 by K + channel modulations 30:208 in thermal models of nociception 30:205 of furosin 30:208 of gallic acid 30:208 of geraniin 30:208 of Phyllanthus genus 30:208 of quercetin 30:208 of rutin 30:208 of stigmasterol 30:208 Analgesic mechanism 30:193 Analgesic potencies 30:800,813 ofopioid analogues 30:800,813 Analgesic properties 30:207 of menthol 30:207 Analgesics 30:191 in pain treatment 30:191 natural products as 30:191 Analgesics/antipyretics 30:192 acetaminophen as 30:192 dipyrone as 30:192 Anandamide 30:195,196 as endogenous cannabinoid 30:195 pharmacological properties of 30:195 SAR of 30:196 Anaplastic carcinoma 26:712 Andalusol 29:102 activity in ACM bioassay system 29:102 activity in CRG bioassay system 29:102 activity in NFkB bioassay system 29:102 activity in NO bioassay system 29:102 activity in TPA bioassay system 29:102
Andrastins 24:452,453 FPTase inhibition by 24:403-464 Andrographolide 29:102 activity in AOS bioassay system 29:102 activity in iNOS bioassay system 29:102 activity in NO bioassay system 29:102 Anencephaly 23:571 Anethofuran 29:83 activity in GST assay system 29:83 ANF-activated membrane bound guanylate cyclase 25:523 Angelica keiskei 30:55,56 inhibition of catecholamineinduced vasoconstriction by 30:55 use as analeptic 30:72 use as diuretic 30:72 use as lactagogue 30:72 use as laxative 30:72 use in catecholamine-induced vasoconstriction 30:72 use in coronary hcart diseases 30:72 use in hypertension 30:72 Angiogenesis 2~:757;30:56,61-64 by fibroL.ast growth factor 30:56 by matrigel 30:56 effect of matrigel/VEGF/heparin mixture 30:61 effect of triterpenoids on 30:61,62 in vivo 30:61 inhibition by carp oil 30:69 Angiogenesis inhibition 24:888-890 by magnosalin 24:888-890 Angiogenesis inhibitor 22:262 Angiogenesis inhibitory activity 24:406 of phosphocombretastatin (disodium salt) A-4 24:406 Angiogenic response 30:61 role ofheparin 30:61 Angiostatic activity 21:435 Angiotensin II-induced hypertension 25:595
1017 Angustone B 28:228 biological activity of 28:228 Anilidopiperidines 30:200 in central analgesic activity 30:200 Animal models with osteoporosis 30:499 effect of 1ot,25(OH)2D4 on 30:499 Animal product 24:904-916 effect on cardiovascular arrythmia 24:904 Animals 26:221;26:943 metastatic secondary tumor in 26:221 NO-mediated apoptosis in 26:943 Annonaceous acetogenins 28:437 as complex I inhibitor 28:436,437 Annona glabra seeds 28:430 acetogenins from 28:430 against Dermatophagoides pteronyssinus 28:430 against Typhlodromus urticae 28:430 Annonidium monni 22:512 for epilepsy 22:512 Annulatophenonoside 30:624 Anolignan A&B 26:224 HIV-1 RT inhibition by 26:224 (-)-Anonaine 24:857 hypotensive effect of 24:857 Anorexia 22:588;30:369 effect of circadian activity on 369 Ansamycin 24:545-546 antiviral microbial-derived compound 24:545-546 Ansamycin antibiotics 23:51-106 antitumor activities of 23:96 biological properties of 23:93 cytotoxic activities of 23:96 Ant repellant 6:142 neoxanthin as 6:142 Antagonism 26:240-245 of platelet activating factor (PAF) 26:240-245 Antagonisms 21:601
8-Antagonist activity 30:810,811,817 against DEL antinociception 30:811 in vitro 30:818 of DTAOH 30:810,811 of DTOH 30:810,811 of 5-opioid receptor 30:818 Antagonist cannabinoid receptors 25:532 Antagonist effect 25:533;26:756 of dioxin 26:756 of oripainine 25:533 Antagonistic activity 20:515;21:233; 23:187 ;26:460,1065 Antagonistic alkaloids 21:4 Antagonists 21:52;22:16 ~:-Antagonists 30:807 Antedematose activities 21:633 Anthelmintic activity 1:408,5:552; 23:356;26:425,446,450,451,456,466, 476,478,481,482,487,491 ofpsoralen 23:356 Anthelmintic agents 12:3 Anthelmintics 26:426,431,444,465,478, 479,493;28:331,332 broad spectrum activity of 28:332 diminished activity of 28:331 Anthracycline antibiotics 14:492 antitumor activity of 14:492 Anthracycline antibiotics 21:157 Anthracycline prodrug 21:175 Anthracyclinones 4:318 biological activity of 4:318 cardiotoxicity of 4:318 Anthraquinone-based PKA inhibitors 25:544 Anthraquinones 30:304,307 structure-activity relationship (SAR) of 30:307 Anti-complementary activity of OG 25:17 Anti TNF-a antibody 25:461 Anti-addictive activity 21:95 Antiadrenergic alkaloids 21:102 Anti-AIDS activity 23:705 ofbetulinic acid 23:705
1018
Anti-AIDS agent 11:267 (+)-castanospermine 11:267 Antiallergenic drug 26:759 Antiallergenic effects 12:39826:264, 265 of K-252a 12:398 of staurosporine 12:398 Anti-allergic 30:71,72 baicalein as 30:71,72 Antiallergic activities 18:674;21:656, 657,659,594;23:364;26:759 of coumarin 23:335,356,357, 353,3 68,376,393,550,553 Antiallergic properties 21:660 Anti-angiogenesis 24:875 as biological action 24:875 Anti-angiogenesis action 24:875-925 of Kampo medicines 24:875-926 Antiangiogenic activity 21:437 Antiangiogenic agents 26:757 Antiangiogenic effects 30:63 of ganoderic acid F 30:63 Antianoxic activity 21:585 Anti-anxiety agent 26:413 Anti-apoptotic effects 28:175 Anti-arabic antibodies 29:543 Antiarone B 28:229 biological activity of 28:229 Antiarone F 28:229 biological activity of 28:229 Antiarone G 28:229 biological activity of 28:229 Antiarone H 28:229 biological activity of 28:229 Antiarone I 28:226,229 anti-human immunodeficiency virus (HIV) activity of 28:226 biological activity of 28:229 Antiarone J 28:229 biological activity of 28:229 Antiarrhythmic activity 23:356;30:200 of coumarin 23:335,356,357, 353,368,376,393,550,553 of loreainide 30:200 Anti-ARS2 antibody 25:435 Anti-arthritic agents 22:116 Anti-asthmatic activity 24:852 Antiatherosclerotic activity 23:355,468; 28:257,293
of organosulfar compounds 23:355,455-485 ofpolyphenols 28:257,293 Anti-bacterial 24:25 biological activity of 24:25 Antibacterial action 30:158 of resorcinols 30:158 Antibacterial activities 5:512,747;10:78, 117;11:134;12:398;14:145;20:245, 712 ;21:21,108,109,190,207,213,214, 230,237,262,266,267,275,284,601, 615 ;23:41,126,164,235,258,355,468, 375,472,473,531,534,800;24:573, 856,857;26:226,1002;28:140,688; 30:328,738 of 1,2,3-trithiane 23:235 of 3',4'-dideoxykanamycin 14:145 of 5-methoxydehydrodiisoeugenol 26:226 of acteoside 5:512 of allicin 23:473 of allicin 23:473 of anonaine 24:856,857 ofbenz [a] anthracene antibiotics 11:134 of bicyclic phloeodictine B 28:688 of caryophyllene 23:535 of celastrol 5:747 ofcopalliferol A 23:534 ofcopalliferol B 23:534 of coumarin 23:335,353,356, 357,368,376,393,550,553 of curcmene derivatives 23:164 of curcumene derivatives 23:164 of curcumenes 23:180 of curcumenes 23:180 of dicoumarol 23:354,375 of dicoumarol 23:375 of dihydrodiisoeugenol 26:226 of distichol 23:535 of forsythiaside 5:512 of HA 26:1002 of Hypericumperforatum 30:628 of ikarugamycin 28:140 of ircenals 24:573 of isoeugenol 26:227 of kaempferol 23:535
1019
of myricetin 23:535 of organosulfar compounds 23:355,455-485 of organosulfur compounds 23:355,468 ofphenylpropanoids 5:512 ofresveratrol 23:531 ofresveratrol 23:74,531,534,746 of rhein 30:328 of saframycins 10:78 of SAM 23:41 of SAM MM1 23:41 of sampangine metabolites 23:40 of sennosides 30:328 of sesquiterpenes 23:180 ofsesquiterpenes 23:180 of staurosporine 12:398 of streptomycin 23:41 of streptormycin 23:41 of suspensaside 5:512 of teraxasterol 23:535 of tetrazomine 10:117 of thiosulfinates 23:472 of thiosulfinates 23:472 of toralactone 30:328 of trithiane 23:235 ofurochordamine A 23:258 ofurochordamine A 23:258 ofurochordamine B 23:258 ofurochordamine B 23:258 of a-gurjunene 23:535 of [3-hydroxyacteoside 5:512 Antibacterial agent 5:377 aplasmomycin as 5:377 aurantinins as 5:601 chimeramycin as 5:613 Antibacterial effect 23:135 of [3-glucans 23:107,111,115,135 Antibacterial flavone 30:740 structure of 30:740 Antibacterial macrolide 5:613,747 Antibacterial metabolite 23:165 Antibacterial properties 30:628 against Staphylococcus aureus 30:628 Antibacteriophage activity 21:408 Antibiotic 24:799 biological activity of 24:799
Antibiotic activity 11:130;12:192; 17:283 ;21:188,202,223,239,364,437; 23:649;24:953-954 ;28:121 of 2-isocephems 12:192 of 2-iso-oxacephems 12:192 of celastroloids 23:649 of equisetin 28:121 of HIRE 24:951-954 ofmacrolide 17:283 of semivioxanthin 11:130 of thienamycin 12:188 Antibiotic potency 4:432 of imipenem 4:432 of 1-[3-methylthienamycin analogue 4:432 Antibiotic T-1384 5:549 Antibiotics 30:738 ansamycin 9:431-445 bio-organic chemistry of 9:431-445 biosynthesis of 11:207-213 from microorganisms 5:589 isoquinolinequinones 10: 77-145 mitomycin 9:431-445 relative configuration of 6:261 shikimic acid derived 11:182-191 sugar components of 11:213-222 Antibiotics A 26771 B 11:194 by Penicillium turbatum 11:194 Anti-bleeding activity 26:56 of Dianthus superbus var. longicalycinus 26.56 Antibodies 2:345-348;7:29;29:521, 529-532 active sites of 29:529 activity of 29:531 against carbohydrate containing antigens 29:521,536 against Streptomyces pyogenes 29:537 anti-BSA 29:532 anti-gum arabic 29:532 anti-lactose 29:532 antigen complex of 29:531 as vaccines 29:521 immunoglobulin classes of 29:521 in medicine 29:521
1020
inhibition of 29:521,531 inhibition patterns of 29:536 inhibition via agar diffusion data 29:531 role in immunization 29:524 secretion of 29:525 Antibody dependent cell mediated cytotoxicity (ADCC) 25:273 Antibody dependent cellular cytotoxicity (ADCC) 27:803 Antibody directed enzyme prodrug therapy 21:157 natural anthracyclines for 21:157 Anti-CAM IgG 25:491,492 Anticancer activity 14:805;21:135,136; 23:335,356,357,353,368,376,393, 550,553 ;26:741,760,1060;27:807 DNA-damaging natural products with 20:457-500 of vinblastine 14:805 of vincristine 14:805 of flavopiridol 21:135,136 of ecteinascidins 23:253,255 of coumarin 23:335,356,357, 393,550,553 of strychnos bisindole 26:1062 of 18,19-dihydrousambarine 26:1062 of 5',6'-dihydrousambarensine 26:1062 of strychnopentamine 26:1062 of usambarensine 26:1062 of usambarine 26:1062 of magainin-2 27:807 of flavopiridol 21:135 Anticancer agent 14:805;19:511; 22:234;30:291 Scutellaria indica use as 30:291 Anticancer compounds 13:347-382; 14:805 Anti-cancer effects 23:475 ofallyl sufides 23:475 Anticancer peptide 27:799 Arg-D-Trp-NmetPhe-D-Trp-MetNH2 as 27:799 Anticancer treatment 14:805;26:162, 163
GL-311 used for 26:162 TOP-53 in 26:163 vinblastine for 14:805 Anticandidal activity 20:485 Anti-carcinogenic activity 21:585; 22:345 ;28:257,293 of polyphenols 28:257,293 Anticaries activity 18:673 Anti-catarrhal activity 26:398 Anti-ChE activity 21:748 Anticholinergic 21:102 Anticholinergic agents 17:395 Anticholinesterase activity 22:30 Anticholinesterase alkaloid 21:744 Antichromonal action 22:625 Anti-CMV activity 30:404,405 of Sargassum horneri 30:405 of seaweeds 30:404 of sulphated polysaccharide (PS) 30:405 Anticoagulant activity 30:395,399,403 of coumarin 23:335,353,356, 357,368,376,393,550,553 ofheparin derivatives 30:399 ofpolysaccharide (PS) 30:395 of sulphated polysaccharides (PS) 30:403 Anticoagulation 30:838 mechanism of 30:838 Anti-coagulative principles 23:835 Anticoccidial activity 21:401 Anticoccidium agent 4:591 Anti-complement activity 22:136; 25:46;26:340 ofserotonin agonists 25:46 of cyclic AMP-dependent protein kinase 25:46 of serotonin agonists 25:46 Anti-complementary 22:307 Anticonvulsant 22:511,524,534 Afraegle paniculata as 22:511 Arisaema amurense var. serratum as 22:512 Asparagus recemosus as 22:513 Jatropha gossypifolia L. as 22:524 Jatropha multifida L. as 22:524 Lantana camara L. as 22:524 Tetrapleura tetraptera as 22:534
1021 Anti-convulsant activity 24:858;28:176 of bilobalide 28:176 Anticonvulsant agent 22:511,512, 515-517,519,524,532,534 ;26:413 Afraegle paniculata as 22:511 Ampelopsisjaponica as 22:511 Boerhavia diffusa L. as 22:514 Clausena anisata as 22:517 Calliandra portoricensis as 22:515 Cinnamomum camphora as 22:516 Carum carvi L. as 22:515 Arisaema amurense vat. serratum as 22:512 Calliandra portoricensis as 22:515 Carum carvi L. as 22:515 Cinnamomum camphora as 22:516 Clausena anista as 22:517 Daucus carota w. as 22:517 Jatropha gossypifolia L. as 22:524 Jatropha multifida L. as 22:524 Lantana r L. as 22:524 Solanum dasyphyllum as 22:532 Solanum nigrum as 22:532 Tetrapleura tetraptera as 22:534 Anticonvulsive action 26:399 Anticonvulsive agent 22:512 Ampelopsisjaponica as 22:512 Anti-crocin mAb 25:957 Antidepressant 30:603,624,627 activity ofhyperforin 30:627 activity of Hypericum perforatum as 30:624 use of hypericin as 30:624 use of Hypericum perforatum 30:627 Antidepressant drugs 21:101 Anti-depressant effects 28:177 of Ginkgo biloba L. 28:177 Antidepressant efficacy 30:335,626,627 chemical modification of 30:627 of Hyperici herb 30:335 of hypericin 30:626 Antidepressant-like effect 30:204,334 in forced swimming test 30:334
in mice 30:204 of Hyperici herb 30:334 of Siphocampylus verticillatus extract 30:204 Anti-dextran antibodies 29:538 of the IgG class 29:538 Anti-diabetic agents 7:47;30:340 quinonic derivatives as 30:340 Antidiarrheal activity 30:200 of loperamide 30:200 Anti-digoxin antibodies 15:374 Antidote 5:751 for scorpion sting 5:751 for snake bite 5:751 Antidote activity 22:460,462-482 Antidysenteric agent 5:758 Antiedema activity 12:384;22:443 of staurosporine 12:384 Antiemetic agent 24:900 gingerol as 24:900 Antiepileptic 22:516 Celastrus paniculta as 22:516 Withania somnifera L. as 22:535 Antiepileptic activity 22:516,517,532, 535 of Celastrus paniculata as 22:516 of Citrullus colocynthis as 22:517 ofSolanum sodomaeum L. as 22:532 of Withania somnifera L. as 22:335 Antiepileptic agent 22:517,532 Citrullus colocynthis as 22:517 Solanum sodomaeum L. as 22:532 Antiepileptic drugs (AED) 22:507 Antiestrogenic activity 26:221 Antiestrogenic effects 26:209 Anti-exudative activity 22:97 Anti-fatty liver 30:94 action of Platycodi radix 30:94 Antifeedant 17:153,234,23724:845,866 bioassay of 24:866 biological activity 24:845 Antifeedant activity 2:277;10:425; 21:254,273,611,770;23:319,321,
1022
341-344,348,666,670,671 ;24:101; 26:461,851 ;28:480;30:696 against insects 23:666 against mammals 28:480 of (-)-specionin 10:425 of 1-deoxy-2 p,3 [3-epoxynagilactone A 28:480 of allicin 23:341 of amphotericin B 23:343 ofbombinins 23:341 ofbruceantin 23:321 of Celastrus angulatus 23:666 of chlorodimeform 23:319 of chlorodimeform 23:319 of cispentacin 23:344 of culmorin 23:344 of drosomysin 23:341 of griseofulvin 23:343 ofjaspamide 23:341 ofjuglone 23:342 ofleukotoxin 23:341,345 of majusculamide 23:344 ofnagilactone A 28:480 ofnagilactone C 28:480 ofneoquassin 23:319 ofnigakilactone E 23:319 of Pachyrrhizus erosus 24:779, 822-826 ofperoxyplakoric acid 23:341 ofpicrasin B 23:319,321 ofpradimicin A 23:343 of pristimerin 30:696 of quassin 23:319,321 of sesquiterpenes 23:670,671 of sinharine 23:343,348 of tannic acid 23:341 of tingenone 30:696 of tomatin 23:342 of xanthylletin 23:342 of yadanziolide A 23:321 of yurendide 23:341 Antifeedant assays 18:771-774 Antifeedant effect 26:853,861,863,871, 874,876 Antifeedant properties 22:234 Antifeedant sequiterpenes 23:668,669 from Elaeodendron buchananii 23:669 from Euonymusfortunei 23:668
from Euonymus bungeanus 23:668 of SAM 23:41 Antifeedants 7:395-397;29:129 polygodial as 29:129 warburganal as 29:129 Anti-fertility action 2:229-231 ofplumbagin 2:229-231 of Plumbago zeylanica 2:229, 231 ofisoshinanolone 2:229-231 Anti-fertility activity 5:754 antifertility activity of 21:759 antifungal activitiy of 21:758 ofpseudolaric acid B 21:759 Antifouling 17:93,98 Anti-fouling assay 21:36 Anti-fungal 24:25,799 biological activity of 24:25,799 Antifungal activities 21:186,192,197, 203,206,213,214,218,221,226, 227,233-235,223,238,240,389, 391,399,404,405,435,599-662; 22:626;23:3,4,271,341,344,348, 468,473,798,801354,368 ;26:227, 228,553,1098;28:4;66,473,475,686; 30:327,738,629 against Candida albicans 30:327,629 from Hypericum roeperanum 30:629 of (E)-8(17), 12-1abdadiene15,16-dial 23:798 of (E)-8b, 17-epoxylabd- 12-ene15,16-deol 23:798 of (E)-8 [3,17-epoxylabol- 12-ene15,16-dial 23:798 of 2-hydroxynagilactone F 28:475 of 2-thioxopyrrolidines 26:1098 of 3,4,3 ',4'-tetramethoxylignan7-ol 26:228 of 3,5'-diallyl-2'-hydroxy-4methoxybiphenyl 24:861 of 3,5-Diiodetyramine 23:235 of 3-methoxysampangine 23:4 of 3-methylsampangine 23:9 of 4'-O-demethldehdropodophyllotoxin 26:227
1023
of alga 5:342 of allicin 23:341,473 of allicin 23:473 ofambigol A 23:342 ofambigol A 23:342 ofamphotericin B 23:343 of aumulone 23:342 of Batzella sponge 28:685 of biphenyl ether,4,4'-diallyl-2,3'dihydroxybiphenyl ether 24:861 ofbombinins 23:341 ofbroussoflavonol G 28:4 ofbroussonin A 28:16 ofbroussonin B 28:16 of canaliculatol 23:534 of cardigone 23:342 of cispentacin 23:344 of coelenterate 5:342,368 of cordigol 7:408 of cordigone 7:408 of coumarin 23:335,356,357, 353,368,376,393,550,553 of culmorin 23:344 of discobahamin A 23:341 of drosomysin 23:341 offlavolol 3-methyl ether 7:414 of flavonoids 7:413 of garcigerrin 7:423 of glutionosone 23:343 of griseofulvin 23:343 of humulone 23:342 of hydroquinone uncinatone 7:408 ofintrapetacin A 28:66 ofintrapetacin B 28:66 ofjaspamide 23:341 ofjuglone 23:342 oflabdadiene-15,16-dial 23:799 ofleukotoxin 23:341 of LL-Z1271c~ 28:473 of magnolol 24:861 of majusculamide 23:344 of mollusk 5:342 ofmyristic acid 23:348 ofnagilactone C 28:475 ofnagilactone E 28:475 of nanaomycins 11:127 of naphthoxirene 7:423
of napthoxirenes 23:342 ofoidiodendrolide B 28:475 ofoidiolactone D 28:475 of ooponol 23:354 of oosponol 23:354 of organosulfar compounds 23:355,468 of organosulfur compound 23:353,468 ofpapsorbic acid 23:342 ofPenstemon r o s e u s 24:838 ofperoxyplakoric acid 23:341 of polyoxins 23:343 ofpradimicin A 23:343 ofpseudolaric acid B 21:758 ofpterocarpans 7:414 of pyrrolnitrin 23:344 of pyrrolnitrin 23:344 ofrhizocticin A 23:344 of rhizocticin A 23:344 of SAM 23:41 of SAM MM1 23:41 of sampangine metabolites 23:3 ofsampangine metabolites 23:40 of sampangines 23:3,9,341 of semivioxanthin 11:130 of sesquiterpenes 2:287 of sinharine 23:343 of sponge 5:342,368 of streptomycin 23:41 of tannic acid 23:342 of thujaplicins 23:343 of tomtin 23:342 of tunicate 5:342 of urdamycin 11:134 of vaticaffinol 23:534 of vitamin A 23:271 of vitamin B 23:271 of vitamin B 23:271 of xanthones 7:410;30:629 ofxanthyletin 23:341 ofyurenolide 23:341 Antifungal activity evaluation 23:41 of SAM 23:41 of SAMMI 23:41 of SAMM2 23:41 of SAM MM1 23:41 of streptomycine 23:41
1024
Antifungal agents 4:513;17:239;26:368; 24:406 activity of 17:378 macrolide as 17:16 sesquiterpene dialdehydes 17:233 epothiolones as 24:406 Antifungal antibiotic 5:597,607,613; 21:388 cerulenin as 5:613 irumamycin as 5:597 phhoamycin as 5:607 Antifungal compounds 7:406,408,415; 23:13 Antifungal drug 23:3 sampangine as 23:3 Anti-fungal effects 23:481 of allyl sufides 23:481 Antifungal flavones 7:413 Anti-fungal green house 24:864 bioassay of 24:864 Anti-fungal holothurin 28:597 from Psolus patagonicus 28:597 Antifungal metabolites 21:187,190 from biological control fungi 21:187 Antifungal property 23:335-393 of coumarin 23:335,356,357,353 368,376,393,550,553 ;27:381 Antifungal pseudolaric acid B 21:754 Antifungal pyridone 21:213 Antigen 24:939 Antigen activation 30:592 induced by TPA 30:592 in Raji cells 30:592 Antigen modifications 29:533 by borohydride methods 29:533 by carbodiimide methods 29:533 by isoelectric focusing 29:533 by lipid isoelectric focusing 29:534 by monosaccharide oxidation 29:533 O-Antigen from Salmonella anatum 6:262 synthesis of 6:262 Antigen preparation 29:528 from CNBr activated sepharose 29:528
of glycoconjugates 29:528 of glycoproteins 29:528 of immunoadsorbents 29:528 of microbes cell walls 29:528 Antigen-antibody reaction 21:659 Antigenic activity 26:1126 I-Antigenic determinant 10:483 O-Antigenic polysaccharide from Pseudomonas aeruginosa 14:236 from Salmonella newington 14:233 from Shigella flexnert 14:233 Antigenic specificity 4:197 Antigenotoxic agent 26:271 II Antigens 10:457,461 I Antigens 10:457-461 Anti-glycemic effects 24:902-904 of humulones 24:902-904 Antiglycosuric activity 26:398 Anti-HeLa cell growth 21:695 Anti-Helicobacter pylori activities 28:234,241,243 of 6,8-diprenylorobol 28:243 of dihydrolicoisoflavone A 28:243 of formononetin 28:241 ofgancaonin I 28:243 ofgancaonol B 28:243 ofgancaonol C 28:243 of glabrene 28:241 of glabridin 28:241 ofglyasperin D 28:243 of glycyrin 28:243 ofglycyrol 28:241 of glycyrrhetic acid 28:241 of glycyrrhizic acid 28:241 ofisoglycyrol 28:241 of isolicoflavonol 28:243 of licochalcone A 28:241 oflicochalcone B 28:241 oflicoisoflavone B 28:241 of licorice flavonoids 28:234 of licorice-saponin 28:241 of licoricidin 28:241 of licoricone 28:243 of liquiritigenin 28:241 of liquiritin 28:241 of 1-methoxyphaseollidin 28:243
1025 of 3-O-methylglycyrol 28:243 of vestitol 28:243 Anti-hepatitis activity 21:662 Anti-hepatitis B agents 20:527 Antihepatitis sarmentosin 21:737 Antihepatotoxic 30.749 effects of apigenin 30:749 effects ofluteolin 30:749 effects of nepetin 30:749 effects of quercetin 30:749 Antihepatotoxic activities 17:377; 21:651 ;26:256;27:660 Antihepatotoxic agents 26:255 3-deoxysilychristin 26:255 silandrin as 26:255 silchristin as 26:255 silybin as 26:255 silydianin as 26:255 silymonin as 26:255 Antihepatotoxic effect 23:479;25:99 ofallyl sufides 23:479 of OGs from Abri Herba 25:99 of OG 25:98,99 Antiherpes activity 5:565 Antiherpetic activity 21:718 Antiherpetic drug 30:400 acyclovir 30:400 complications of 30:400 Antihistaminic activity 30:200 of astemizole 30:200 Antihistaminic dispacamide C 25:870 Antihistaminic dispacamide D 25:870 Antihistaminic drugs 26:262 Anti-HIV activity 19:511,748;21:132, 133,149,252,269,664,665 ;23:316, 533,534,687,704 ;24:742,743 ;30:226, 396,397,399 activity of 30:399 of bergenin 23:535 of dibalanocarpol 23:535 ofMerremia peltata 30:397 of natural quassinoid glycosides 23:316,318 of balanocarpol 23:533,534 of neotripterifordin 23:687 of orthosphenic acid 23:704 of polyphenols 30:226 of potassium salt ofcaffeic acid tetramer 24:742,743
ofsalaspermic acid 23:704 of sodium salt of caffeic acid tetramer 24:742,743 of tripterifordin 23:687 Anti-HIV agents 24:742;30:227,397 aryltetralins 24: 742 mechanism of action of 30:397 polyphenols as 227 Anti-HIV cytopathicity activity 30:399 of marine invertebrates 30:399 Anti-HIV flavonoids 28:226 2-arylbenzofuran as 28:226 from Glycyrrhiza species 28:226 from moraceous plants 28:226 AntiHIV licochalcone 21:740 Anti-HIV polysaccharide (PS) 30:399 from marine alga 30:399 Anti-HIV sulphated polysaccharide (PS) 30:399,400 from Ganoderma lucidum 30:400 from Lentimus edodes 30:400 natural sources of 30:399 Anti-HIV therapeutic agents 30:399 Anti-HIV triterpenes 21:664 Anti-HIV-assay 20:535,536 Anti-HIV-screening 13:665 Antihormones 20:515 Anti-HRP monoclonal antibodies 25:334 Anti-HSV activity 30:403 of fucan sulphates 30:403 of Leathesia difformis 30:403 ofSargassum horneri 30:403 Anti-HSV agents 30:401 Anti-HSV sulphated polysaccharide (PS) 30:403 from Ganoderma lucidum 30:403 Anti-HSV-1 activities 21:665,695,718 Anti-HSV-1 bioassay 21:698 Anti-human immunodeficiency virus (anti-HIV) 28:631 activity of Didemnum sp. 28:631,634 Anti-human immunodeficiency virus (HIV) activity 28:225,226 ofantiarone I 28:226 ofbroussoflavonol B 28:226
1026
ofbroussoflavonol C 28:226 ofgancaonin R 28:226 ofglyasperin A 28:226 of glycyrol 28:226 ofkazinol B 28:226 of kumatakenin 28:226 ofkuwanon H 28:225 oflicochalcone B 28:226 ofmoracin C 28:226 of morusin 28:225 of mulberry tree 28:225 of norartocarpetin 28:226 of prenylflavones 28:225 of wighteone 28:226 Antihyaluronic activity 26:556 Anti-hyperanalgesic activity 201 of SDZ-249-665 30:201 Anti-hyperglycemic 24:875 as biological action 24:875 Anti-hyperglycemic action 24:875-925 of Kampo medicines 24:875-926 Antihyperglycemic activity 18:672; 19:351 Anti-hyperglycemic effect 24:902-904, 917-919,919-922 chemical structure of 24:916 N-containing sugars of 24:916-920 of humulones 24:902-904 of isohumulones 24:902-904 of Morus spp. 24:917 of N-containing sugar 24:917 of timosaponin 24:919-922 Anti-hyperglycemic medicinal plants 24:916-920 Antihyperlipidaemic action 30:94,107 of chondroitin sulfate 30:107 of Platycodi radix 30:94 Anti-hypertensive activities 21:501 of Forsythia suspensa 5:513 of K-252a 12:398 of staurosporine 12:384 of suspensaside 5:513 Antihypertensive effects 26:235,236 Antihypoxic activity 18:373 Antihysteric 22:526 Muntingia calabura L. as 22:526 Antihysteric agent 22:526 Muntingia calabura L. as 22:526
Anti-i-antibody 10:480 Anti-IFN-y 25:464 Anti-IL-1 antibody 25:464 Anti-IL-6 antibody 25:464 Antiinfective drugs 23:111 Antiinfective effect 23:135 of ~-glucans 23:107,111,115,135 Anti-infective plants 30:396 in traditional medicine 30:396 Anti-inflammation 24:875 as biological action 24:875 Anti-inflammation action 24:875-925; 30:72 of baicalein 30:72 of Kampo medicines 24:875-926 Anti-inflammatory 24:799,852,869 biological activity 24:25,799,845 effect ofshin-I 24:852 bioassay of 24:869 Anti-inflammatory activities 5:367; 13:647;17:137,376;18:775;21:130, 134,153,152,312,591,594,690,616, 656,657;22:93,119,307,345,361; 23:158,297,512,602,832;25:43; 26:340,341,343,391,398,400,401, 403,404,406,415,418,482,556,558, 741,759,1035 ;27:660,858 ;28:200, 257,293 ;671,844;30:206,207,224, 225,292,320,689,743 Copaifera riticulata for 22:360 cytotoxic activity 23:180 Heisteria pallida for 22:360 of 2-substituted 3-chloro- 1,4naphthoquinones 30:320 of 3',4-O-dimethylcedrusin 22:361 ofbroussoflavonol G 28:4 of califomian sponge 28:671 ofcembranes 23:180 of cembrones 23:180 of coumarin 23:335,356,357, 353,368,376,393,550,553 ofCurcuma comosa 26:884 of curcumenoids 23:835 of curcuminoids 23:835 ofDrymis winteri as 30:206 of genus Morus 28:200 of kallilolides 23:180 of kallilolides 23:180
1027 ofMorus nigra 30.207 of phenolic triterpenes 30:689 ofpolyphenols 28:257,293 of polyphenols 30:224,225 ofProtium kleinii 30:206 of pseudopterolides 23:180 of pseudopterosins 23:153,180 of pseudopterosins 23:158,180 of pseudoterolides 23:180 of pseudoterolides 23:180 of saikosaponins 23:512 of saikosaponins 23:512 of Salvia desoleana 26:416 of samaderines 23:297 of samaderines 23:297 ofSaponaria officinalis 26:27 of secopseudopterosins 23:180 of secopseudopterosins 23:180 of secosterols 23:168,180 of Sideritis javalambrensis 30:292 of Sideritis mugronensis 30:292 of sterols 25:43 of Tripterygium wilfordii 30:689 of triterpenes 30:689 of triterpenoids 25:43 Anti-inflammatory agent 5:753;7:397, 14:315 ;21:616;24:898;26:32 aconitine as 24:898 barbatoside A as 26:56 barbatoside B as 26:56 from Dianthus barbatus 26:32,56 Anti-inflammatory diterpenoids 23:688 Antiinflammatory drug 17:130;23:111 Anti-inflammatory effect 26:262,263, 264;30:206 of feverfew 30:206 of K-252a 12:398 of parthenolide 30:206 of staurosporine 12:398 Anti-inflammatory inhibitor 23:175 Anti-inflammatory reactions 30:72 Anti-influenza activity 30:407,408 of Cochlodinium polykrikoides 30:408 of Crenomytilus grayanus 30:408 of Nothogenia fastigiata 30:408
ofPinus parviflora 30:407 ofSpirulina platensis 30:408 of Ulva lactuca 30:408 Antijuvenile hormones 22:395 Anti-lactose antibodies 29:538 Antileishmanial activity 21:674,744; 26:229,790,813,887,789,790,791, 800,805,807,810,811,821,828,830; 30:742 of Baccharis dracunculifolia 30:742 of Baccharis genistelloides 30:742 ofBaccharis incarum 30:742 of Baccharis pentlandii D.C. 742 of Baccharis salicifolia 30:742 ofBaccharis tricuneata 30:742 of genus Baccharis 30:742 of lignans 26:229,790,813,887 in vitro 30.'742 Antileukemic P388 activities 21:770 Antileukemic activity 1:305;4:232; 7:382-387,390;17:348;23:70,285, 490,649;24:573; ofansamitocin P-3 23:71 of asperdiol 23:490 of asperodiol 23:490 of bisbrusatolylglutarate 23:305 of bisbrusatolylmalonate 23:304 ofbruceanol A 23:313,288 ofbruceanol B 23:313,288 of brusatol 23:304 ofbrusatolyl esters 23:304 ofditerpene triepoxides 23:649 of gnidimacrin 23:490 of ircenals 24:573 ofjatrophone 23:400,490 of natural maytansinoids 23:70 of semisynthetic maytansinoids 23:70 Antileukemic principle 23:70 Antileukoderma 23:356 methoxsalen 23:356 Antileukoderma activity 23:356 of methoxsalen 23:356 Antilipoperoxidant 22:307;30:223 Anti-malarial activity 7:391-393,424; 21:346;23:301,838;24:282;26:779, 1036
1028 of 3-geranyloxy-6-methyl- 1,8dihydroxyanthrone 7:424 of 3-geranyloxy-6-methyl- 1,8dihydroxy anthraquinone 7:424 of acetylvismione D 7:424 of amarolide 23:301 of artemisinin 7:424 of chaparrin 23:301 of chaparrinone 23:301 of chloroquine 23:301 of Cinchona succiruba 26:779 of glaucarubolone 23:301 of holacanthone 23:301 of quassinoids 7:391-394; 23:285-333 o f quinine 7:424 ofvismione D 7:20 Anti-malarial agents 8:391-394,351; 20:516-521 ;30:330 against chloroquine-sensitive (T9-96) 30:330 Antimalarial assay 30:596 in vivo 30.'596 of alkaloids 30:596 Antimalarial compounds 22:145 Antimalarial drugs 25:327,360;26:1035; 30:595 as chemosensitizers 30:595 as resistance-modifiers 30:595 chloroquine sensitivity in 30:595 Antimalarial effects 30:561,588,595, 597 of Hernandia moerenhoutiana 30:561 of Hernandia voyronii 30.561, 577 ofHernandia sp. 30:588 ofhervelines A-D 30:595 of laudanosine 30:595 of reticuline 30:595 Antimalarial naphthoquinones 30:330 atovaquone 30:330 Antimalarial therapies 25:361 Anti-metastatic activity 28:559;30:56, 58,59,60,64,69,152,292,329,628,629, 738 against Bacillus subtilus 30:293 against gram-positive bacteria 30:629
against Klebsiella pneumonia 30:293 against Staphylococcus aureus 30:293,329 against Staphylococcus epidermidis 30:293 chemical instability 30:628 from Ganoderma lucidum 30:58 from Hypericum perforatum 30:628 from Hypericum japonicum 30:629 from medicinal plants 30:738 from novoimanine 30:628 in mice 30:59 of carp oil 30:56,64,69 of flavonoid 30:292 of Ganoderma lucidum 30:60 of Ginkgo biloba 30:152 of hyperforin 30:628 of natural products 28:559 of triterpenoids 30:58 of phloroglucinol derivatives 30:629 uses in folk medicine 30:738 Antimetastatic agents 19:351 Antimetastatic effect 16:93;25:441 on CVS 25:441 Antimetastic immunity 25:429 Anti-microbial 24:863-864 biological activity 24:799 bioassay of 24:863-864 Anti-microbial action 24:112 Anti-microbial activity 5:752;10:443; 15:327-339;18:776-778;21:153, 235,257,401,571,573,591,596,597, 599,606;22:626;23:94,153,180,233, 237,249,262,268,267,346,353,522; 24:64,69,206,330,331-334,402,403, 404,406,417,418,443,470,485,859, 1091,1092,1189;26:64,330,401,402, 1189;27:807;28:62,224,257,293; 28:698,671 against Candida albicans 5:752 against Clostridium difficile 5:601 against Clostridium perfringens 5:601
1029
against gram-positive bacteria 23:94 against Proteus mirabilis 5:752 against Proteus vulgaris 5:752 against Staphylococcus aureus 5:752 of (-)-acetomycin 10:443 of 13-methylpentadecanoic acid 26:64 of phenylethanoids 26:330 of 3-O-methylglycyrol 28:224 of 3 f3-O-cis-p-coumaro yl alphitolic acid 28:62 of 3 [3-O-cis-p-coumaro yl maslinic acid 28:62 of 3 [3-O-trans-p-coumaro yl alphitolic acid 28:62 of 3 [5-O-trans-p-coumaro yl maslinic acid 28:62 ofalphitolic acid 28:62 of AMOX 28:224 of amphibian venoms 15:327-339 ofbetulinic acid 28:62 of californian sponge 28:671 of coumarin 23:335,356,357, 353,368,376,393,550,553 of cryptolepine 5:752 of cyclocolorenone 24:859 of defensins 23:346 of dimer triterpenes 18:776-778 of dithiocarbonates 26:1091, 1092 of essential oil 21:571,596 ofeudistomin U 23:267 of eudistomins 23:233,262,268 of formononetin 28:224 of Fraxinus ornus 26:334 ofgancaonin I 28:224 ofgancaonol B 28:224 of glabrene 28:224 of glabridin 28:224 ofglyasperin D 28:224 of glycyrin 28:224 of glycyrol 28:224 of halistanol sulfate 28:698 of HMPT 26:1091,1092 of hydroxycoumarins 26:330
of isoglycyrol 28:224 of isolicoflavonol 28:224 of lamellarins 23:249 of Licania heteromorpha vat. heteromorpha 28:62 oflicochalcone A 28:224 oflicochalcone B 28:224 oflicoisoflavone B 28:224 of licorice flavonoids 28:224 of licoricidine 28:224 of licoricone 28:224 of liquiritigenin 28:224 of liquiritin 28:224 of medrrhodine A and B 5:618 of MMTP 26:1091,1092 of MTBI 26:1091,1092 of polyphenols 28:257,293 of pseudopterosins 23:153,158 of Salvia officinalis 26:402 of Salvia sclarea oil 26:401 of secoiridoids 26:330 of secopseudopterosins 23:180 of secopseudoterosins 23:180 of sesquiterpenes 2:287,288 of theonellapeptolides 26:1189 of triterpenes 18:776-778 oftyramine 23:237 of verbascoside 23:522 of vesititol 28:224 Antimicrobial agent 5:753 Antimicrobial alkaloids 21:109 Antimicrobial consitituents 21:607 Antimicrobial peptide 22:83 Antimicrobial properties 27:378 Antimicrosporidial activity 26:458 Anti-migrane principle 24:849 in Tanacetum parthenium 24:849 Antimitotic activity 5:461 ;23:359,376; 30:224 of coumarin 23:335,356,357, 353,368,376,393,550,553 of gigantecin 9:396 oflignans 5:461 ofpolyphenols 30:224 Antimitotic agent 22:482;30:5 discodermolide as 30:5 Antimitotic inhibitory activity 24:406 ofcombretastatin A-4 24:406
1030 Anti-mu stimulation 25:272 Anti-mutagen 24:851 Antimutagenic 21:641 Antimutagenic activity 21:583,584,585, 616,641,642;23:107;26:1099,1100; 30:315-317,765 of [3-glucans 23:107 of chlorophyllin 30:765 of quinones 30:315-317 Antimutagenic agent 22:307 Anti-mutagenic effects 23:478;26:510 ofallyl sufides 23:478 Antimycine A 16:694 antifungal agent 16:694 Antimycobacterial activity 23:4,9 of 3-methylsampangine 23:9 of sampangines 23:9 Antimycoplasmal activity 11:127 of nanaomycins 11:127 Antimycotic activity 22:70,81 ;23:4 Antimycotic/antimycobacterial activity evaluation of 23:4 3-methoxysampangine 23:4 Antinematodal activity 26:425,433, 456,457,464,472,483,484,488,494 Antinematodal agents 26:456 Antinematodal effect 26:481 Antineoplasic activity 21:389;28:470 against P 388 cells 28:470 Anti-neoplasmatic activity 27:378 Anti-neoplasmic activity 27:386 Anti-neoplastic activity 4:29;22:248, 558 ;24:309-318 ;30:732 of plants 30:732 Antineoplastic agent 28:145,648-49 dolastatin 3 as 28:648 dolastatin 10 as 28:145,649 Antineoplastic drugs 26:158,169,214, 799,825 Antineoplastic glycoproteins 7:285 Antinociception 30:204,802,805 in vivo 30:805 inhibition by opioid receptor antagonist 30:204 monoamine-synthesis inhibitor 30:204 Antinociception action 30:201,204,205, 206,207,800,804,814,815,816
by GABAergic receptor 30:204 by intracerebroventricular 30:814 by noradrenergic receptor 30:204 by serotonergic receptor 30:204 in capsaicin model of pain 30:205 in mice 30:814,816 in neonate rats 30:206 in rats 30:814 in vitro 30:804 in vivo 30:207 mechanism of 30:205 of (-)-menthol 30:207 of (+)-allomatrine 30:205 of (+)-matrine 30:205 ofbiflavonoids 30:207 of cannabinoids 30:194 of cis-8,10-di-N-propyllobelidiol hydrochloride dihydrate (DPHD) 30:204 of DEL 30:800 of DEL C analogues 30:815 ofdeltorphin B 30:804 of DER 30:800 of dispsacus saponin C 30:204 of drimanial 30:206 of glycopeptides 30:816 of hodgkinsin 30:205 of kalopanaxsaponins-A 30:203 of kalopanaxsaponins-I 30:203 of morusin 30:207 of naltrindole 30:816 of piperidine alkaloid hydrochloride 30:204 ofprenylfiavonoid 30:207 ofProtium kleinii 30:206 of Rheedia gardneriana 30:207 of SDZ-249-665 30:201 of Siphocampylus verticillatus extract 30:204 oftormentic acid 30:207 via glutamate NMDA receptors 30:205 Antinociceptive activity 21:591 Antinociceptive agent 30:205 incarvillateine as 30:205
1031 Antinociceptive properties 30:206 of Drymis winteri 30:206 Anti-obesity 30:79,88,94 action of 30:94 action of saponin 30:94 effects of 30:79 mechanism of 30:88 natural products as 30:79 Anti-obesity action 27:398,400,402,403 of chitosan 27:402,403 of natural products 27:398 ofodong tea 27:400 of soyasaponins 27:398 Anti-obesity activity 30:88 of Platycodi radix 30:88 Anti-obesity effector 30:80,82 from oolong tea 30:82 Anti-obesity effects 30: 86,100 in high-fat diet-treated mice 30:86,101 inhibitory actions of 30:86 of chitin-chitosan 30:100 ofoolong tea 30:86 Antioxidant 4:495;9:371,372;21:618; 23:771 ;24:845,868 ;30:524,744 bioassay of 24:868 biological activity 24:845 garlic acid as 23:771 protective functions of 30:744 vitamin C (ascorbic acid) 30:524 vitamin E (tocopherol, TOH) as 30:524 Antioxidant activities 21:599,600,618; 22:308,321,345 ;23:395,534,535,742, 772,773,845 ;25:59;30:173,224,225, 289,320,321,524,561,743,745; 26:250,255,509,556,672,763,768, 887,1005,1006;28:4,16,17,63,179, 257,293,773 of c~-tocopherol 26:1006 of 3-hydroxycoumarins 30:225 of 8-hydroxy-naringenin 28:64 of alizarin 26:672 of anthocyanin pigments 23:773 of anthraquinones 30:320 of apigenin 23:742,748 of baicalein 30:289 of baicalin 30:289 of broussoaurone A 28:16,17
of broussoflavan A 28:16 of broussoflavonol F 28:17 of broussoflavonol G 28:4,17 of carotenoids 30:524 of cassumunin A 23:845 of cassumunin B 23:845 of cassumunin C 23:845 of C-glycosylflavones 23:772 of chrysoeriol 23:742 of cyanidin 23:536,551,742,748 of diosmetin 23:742 of epigallocatechin 23:772 of epigallocatechin gallate 23:742,770,772 of flavonoids 26:765 of garlic 23:771 of Ginkgo biloba L. 28:179 of herbal drugs 25:44 of Hernandia moerenhoutiana 30.'561 of Hernandia voyronii 30.561 of isoorhamnetin 23:742 of isorhamnetin 23:748 of kaempferol 23:742 of kaempferol 3-O-(2"-[3-Dxylopyranosyl)-c~-Lrhamnopyranoside 28:64,65 of kaempferol 3-O-c~-Lrhamnopyranoside 28:64 ofLicania licaniaeflora 28:63 of lignans 23:773 of luteolin 23:742,772 of malvidin 23:742 ofmenadione 30:321 of myricetin 23:742 of natural flavonol 30:224 ofoleanolic acid 23:535 of orcinol 30:173 of peonidin 23:742 of petunidin 23:742 ofphylloquinone 30:321 ofpolyphenol derivatives 30:224 of polyphenols 23:773;28:257, 293 of polyphenols 30:224 of propylgallate 23:772 of quercetin 23:742
1032
of quercetin 3-O-c~-Larabinopyranoside 28:64 of quercetin 3-O-a-Lrhamnopyranoside 28:64,65 of quercetin 3-O-[3-Dgalactopyranoside 28:64 of quercetin-3-O-c~-Lrhamnopyranoside 28:64 ofresveratrol of 23:534 of synthetic pharmacological agents 30:224 of tannic acid 23:395 of tannins 23:442 of taxifolin 3-O-a-Lrhamnopyranoside 28:64 of ubiquinone 30:321 of wogonin 30:289 Antioxidant anthocyanidins 23:742 Antioxidant flavan-3-ols 23:743 structures of 23:743 Antioxidant flavones 23:742 Antioxidant flavonols 23:742 Antioxidant hydroxycinnamic acid 23:744 structures of 23:744 Antioxidant phenolic metabolites 23:739-795 biosynthesis of 23:740 changes during postharvest storage 23:739-795 changes during processing 23:739-795 from fruits 23:739-795 from vegetables 23:739-795 general structures of 23:740 Antioxidant properties 23:739 of flavonoids 23:739 in apples 745 i n apricot 23:745 in cherry 23:746 in citrus 23:747 i n grapefruit 23:747 i n grapes 23:748 i n lemon 23:747 i n olive 23:749 in orange 23:747 in peach 23:749 in pear 23:750 in plums 23:750
in raspberry 23:750 in strawberry 23:752 Antioxidative activity 23:342 of tannic acid 23:342 Antioxidative properties 25:919, 930,935 of chlorogenic acid 25:919, 930,935 Antiparasitic activity 23:359,473; 26:800,817,819 of allicin 23:473 of coumarin 23:335,356,357, 353,368,376,393,550,553 with chalcones 26:800 Antiparasitic properties 30:741 family compositae 30:741 Anti-pathogenic phytoalexin compounds 25:652 Anti-peptide ulcer effect 25:430 of Chlorella vulgaris strain CK 22 (CVs) 25:430 Antiperiplanar orientation 14:457 Antiperoxidative effects 26:249-255 of lignans 26:249-255 Antiperspirant 26:398 Antiphlogistic 17:451 Antiphlogistic activities 21:633 Antiphlogistic drugs 22:114 Antiplamsodial naphthylisoquinoline 26:822 Antiplaque activity 21:613 Antiplasmodial activity 19:587; 26:788-800,805,806,808,810,813, 815,822-824,1035 ;30:596,597 in vitro 30:596,597 of chloroquine 30:596 of dioncopeltine B 26:822,823 ofdioncopeltine A 26:822,823 ofhervelines A-D 30:596 ofisoquinoline alkaloids 30:597 of laudanosine 30:596 of lignans 30:597 of reticuline 30:596 Antiplasmodial agents 20:525 Antiplasmodial flavonoids 26:801 Antiplasmodial phloroglucinol 26:797, 798 Antiplasmodic activity 21:584,614
1033 Antiplatelet activity 23:364;30:594 of coumarin 23:335,356,357, 353,368,376,393,550,553 induced by PAF 30:594 of furofuran lignans 30:594 Anti-platelet aggregation activity 24:741 of syringaresinol 24:741 of yangambin 24:741 Antiplatelet aggregation effect 30:593, 597 in vitro 30:597 ofisoquinoline alkaloids 30:597 of lignans 30:597 Antiplatelet aggregation turbidimetry assay 30:594 activity of Hernandia species in 30:594 activity of lignans in 30:594 in vitro 30:594 Anti-polio virus activity 30:411 of seaweeds 30:411 of Trichilia glabra 30:411 Antipredation 17:93 Anti-progression activity 30:593 Anti-proliferation 24:875 as biological action 24:875 Anti-proliferation action 24:875-925 of Kampo medicines 24:875-926 Antiproliferation effect 30:313,495 against L1210 cells 30:313 of lot,25(OH)zD 30:495 Anti-proliferative activity 21:312; 23:168 Antiproliferative activity 7:419,422, 245,515 ;16:93 ;23:168,180;26:485; 28:17,145 ofbroussoflavonol F 28:17 of broussoflavonol G 28:17 of dolastatin 10 28:145,649 of secosterols 23:168,180 Antiproliferative agent 23:472 Antiproliferative effect 12:393;23:361; 26:752;27:802,862 against HL-60 cells 12:393 against T cells 12:393 against BALB/C mouse 3T3 cells 12:393 against bovine brain cortex
capillary 12:393 ofcis platin 12:390 of endothelial cells 12:393 of human breast cancer 2R-75 cells 12:393 of human myeloid progenitor cells 12:393 in Walker rat carcinoma cell 12:390 LzCB lymphocytes 12:393 mouse isolated microglia 12:393 NIH/3T3 fibroblasts 12:393 ofanticancer drug 12:390 of staurosporine 12:393 of 8-methoxypsoralen (8-MOP) 23:361 Antiprotozaol labdanes 26:810 Antiprotozoal activity 21:435;23:473; 26:452,780,795,797,798,810,825, 1060 of allicin 23:473 of sesquiterpenes 26:807 Antiprotozoal agent 26:230 (+)-nyasol as 26:230,231 Antiprotozoal anthraquinones 26:805 Antiprotozoal drugs 26:793 Antiprotozoal isoquinolines 26:821 from Annonaceae 26:821 from Berberidaceae 26:821 from Hernandiaceae 26:821 from Menispaermaceae 26:821 Antipsoriatic activity 30:323 against growth of human keratinocytes 30:323 ofquinonic compounds 30:323 Anti-psychotic activity 24:1116 of selected natural products 24:1116 Antipyretic 30:825 properties of earthworm 30:825 Anti-pyretic action 24:55 Antipyretic activity 18:775;21:591; 26:1035;28:200 of genus Morus 28:200 Antirachitic activity 30:484 of vitamin D analogues 30:484 Antirachitic factors 17:623 Anti-radical activity 28:257,293 ofpolyphenols 28:257,293
1034
Anti-retro viral drugs 24:487,488 Antiretroviral efficacy 30:628 by inhibition of protein-kinase Cmediated phosphorylation 30:628 of hypercin 30:628 Antirheumatic agent 30:292 Sideritis javalambrensis as 30:292 Anti-rheumatoidal effect 30:204 of hederaginin monodesmodides 30:204 Anti-rubella activity 30:409 of dextran sulphate 30:409 of scleroglucan 30:409 of sulphate derivatives 30:409 Anti-secretory activity 24:799 biological activity 24:799 Anti-seizure activity 24:1111,1112 of selected natural products 24:1111,1112 Antiseptic agent 23:642 teucrium sp. as 23:642 Antiseptic lotion 30:159 resorcinolic lipids used as 30:159 Antiseptic-disinfectant 26:398 Anti-serotonergic activity 24:799 Anti-sigs and anti CD40 25:272 Antispasmodic 22:346,525 Achyrocline satureioides as 22:346 Limnophila chinensis as 22:525 Antispasmodic activity 28:4,670 ofAgelas nakamurai 28:670 ofbroussoflavonol G 28:4 Antispasmodic agent 22:346,525 Achyrocline satureioides as 22:346 Limnophila chinensis as 22:525 Antispasmogenic activity 26:239 Antispasmolytic activity 23:544,591 Anti-stress activity 20:646 Anti-stress effects 28:177 of Ginkgo biloba L. 28:177 Antisweet activity 18:671,672 of gymnemic acid 18:671,672 Anti-thrombic action 30:70 of flavonoids 30:70
Antithrombogenic 30:841 role in EFE-immobilized polyurethane surface 30:841 Antithrombogenicity 30:841 Antithrombotic action 30:289,840 of baicalein 30:289 of baicalin 30:289 of lyophilized powder 30:840 Anti-tick activity 21:621 Anti-TNF- a 25:464 Anti-TNFa-antibodies 25:461 Anti-tobacco mosaic virus activity 23:73 Antitopoisomerase II 25:693 Anti-trichromonal agent 22:617 Antitrypanosomal activity ( Trypanusosma cruzO 26:792 Anti-tubercluosis activity 20:712; 23:318 of natural quassinoid glycosides 23:318 Anti-tubercular activity 5:752,753 Anti-tubercular agents 5:751 Antitumor 30:69,160 extract of earthworm as 30:840 mechanisms of 30:69 Antitumor activity 1:275,316-320-408; 17:17 ;21:137,405,420,435,436,638, 704,733;22:676;23:74,96,126,132, 139,395,445,522,696,721; 24:272-275 ;24:288,845,847,849; 25:43,430,431,438,450-453;26:56, 482,706;27:803;28:211,517,519,559, 560,566;30:3,28,29,55,56,58,59,64, 65,224,314,395,589,690,777,840,841 against intraperitoneally (ip) inoculated leukemia 23:74 antitumor activity of 21:733 discodermolide as 30:3 in mice 30:160 in tumor-bearing animals 30:59 in vivo 30:28 of (-)-acetomycin 10:444,447 of (+)-5-epi-acetomycin 10:447 of acronycine 13:365-382 of ansamycin antibiotic 23:96 of ARS2 25:435,451 ofbenz[a] anthracene antibiotics 11:134
1035 of carp oil 28:566;30:64,65 of celastraceae 30:690 of chitosan 28:560 of Chlorella vulgaris 25:430, 431,450,452,453 of Chlorella vulgar& strain CK 30:777 of Coley's toxin 28:519 of cyanocycline A 10:103 of Dianthus superbus var. longicalycinus 26:56 of didemnins 10:254-257 of diphyllin 5:462 of fish oils 28:566 of fucoidan 30:56 of Ganoderman lucidum 30:58,59 of geldanamycin 23:96 of glycoprotein 30:841 of glycoprotein-rich substance 30:(CVS) 777 of glycosylated component 30:841 of glyfoline 13:375-380 of Hernandia species 30:589 of Hypericum genus 30:314 of indolo [2,3-a] carbazole alkaloids 12:390-396 of ingenol type diterpenes 24:288 of K-252a 12:394,395 of lignans 5:461 of lipids 28:517 of Magnolia officinalis 24:849 of maytansinoids 23:721 of morusin 28:211 of naphthocyanidine 10:104 of natural products 28:559; 30:55,56 of neolignans 24:845,847,849 of nogalamycin 4:335 ofoleic acid 30:56 of pironetin 30:29 ofpodophyllum 26:210 ofpolyphenols 30:224 ofpolysaccharide (PS) 30:395 of pristimerin 5:747 of protein-bound [3-glucan 23:132
of quinocarcin 10:117 of rebeccamycin 12:394 of regelide 23:696 of regelin 23:696 of regelinol 23:696 of saframycins 10:78 of staurosporine 5:275; 12:390-394 of sterols 25:43 of tannic acid 23:395,445 of taxol 12:180 of tetrazomine 10:117 of triterpenoids 25:43;30:58,59 oftriterpenoids in mice 30:59 of tubeimoside 21:733 oftubeimoside 1 21:733 of tuna oil 28:566 ofUCN-01, UCN-02 12:395 of urdamycin 11:134 of verbascoside 23:522 of wilfarlide 23:696 of wilforlide 23:696 pironetin as 30:3 Anti-tumor agent 1:180,268,269; 3:301, 383 ;9:383,385 ;23:82924:1055,1085 Antitumor and/or antimetastatic activity 30:67 of carp oil effects on 30:66 of oleic acid effects on 30:67 Antitumor antibiotic 1:498-7215:592, 593;19:118 Antitumor bioactivity 30:841 from earthworm 30:841 Antitumor bioassay 9:383,386,401 Antitumor bisbolan sesquiterpenes 23:830 [3-atlantone 23:830 c~-curcumene 23:830 r-turmerone 23:830 xanthorrhizol 23:830 Anti-tumor clerodane diterpenes 24:280-282 Anti-tumor compounds 24:269-350 Antitumor drugs 30:164 therapeutic action of 30:164 Antitumor effect 23:107,115,123,126 of glucan 23:107,115,123,126 of lentinan 23:130
1036 Antitumor effect 25:440;27:439 of carp extract 27:439 Antitumor glycoprotein ARS-2 30:778 from Chlorella vulgar& strain CK 30:778 Antitumor immune response 26:921-923 role of nitric oxide in 26:921-923 Antitumor immuno-active glycoprotein 30:776 from Chlorella vulgar& strain CK 30:776 Antitumor immuno-activity 25:432 of Chlorella vulgaris strain CK 22 (CVs) 25:432 Antitumor immunopotentiation 25:454 Antitumor lignans 26:211 austrobailignans- 1 as 26:211 burseran as 26:211 (+)-dimethyliso lariciresino 1-2axyloside as 26:211
(-)-trans-2-(3",4"dimethyoxyb enzyl)- 3- (3 ',4 'methylene dioxybenzyl) butyrolactone as 26:211 diphyllin as 26:211 diphyllin acetate as 26:211 justicin-D as 26:211 peltatins as 26:211 podophyllotoxins as 26:211 stegnangin as 26:211 stegnanol as 26:211 Antitumor mechanism 27:831 of guidimacrin 27:831 Anti-tumor metabolites 1:239 Antitumor plant product 23:71 Antitumor polyethers 5:377 Anti-tumor promoter 24:215-267 curcumin as 24:215-264 Antitumor promoter activity 21:585,705 Anti-tumor promoting activity 23:444, 670,841 of tannic acid 23:444 of tannins 23:444 Antitumor substance 28:569,570 egosterol as 28:570,572 from Agaricus blazei 28:569
isolation of 28:569 mechanism of 28:569 Antitumor therapeutic agent 30:840 Antitumor tubeimosides 21:730 Anti-tumor vascular inhibition 24:406 of phosphocombretastatin (Disodium salt) A-4 24:406 Antitumoral agent 30:691 for skin cancer 30:691 use of Maytenus amazonica 30:691 Antitumoral immune responses 26:923, 924,929 Antitumoral uses 30:732 of plants 30:732 Antitumorigenic agent 23:478 Anti-tumor-promoting activity 21:642; 24:215-264;25:46;30:695 Antitumor-promotor 25:44-46,60 antioxidant activites of 25:59 from herbal drugs 25:44 Antitumour activity 22:97-100,361 of 3',4-O-dimethylcedrusin 22:361 of friedelone 22:97-100 of hopane quassionoid 22:97-100 of lanostane lupane 22:97-100 of oleanane 22:97-100 Anti-tussive activity 17:633;28:200 of genus Morus 28:200 Antiulcer activity 22:410,419 Antiulcerative properties 21:410 Antivectorial activity 21:591 Anti-venom alkaloid 1:239 oxidation 1:239 Antiviral activities 5:461,563;10:608, 609,619,620; 17:146 ;21:132,148, 150,393,435,600,615,662,690,718; 22:307,361 ;23:233,268,233,346,395, 473,512,531,703;25:114;26:169,222, 224,226,344,452,741,759;27:482; 28:257,293 ;30:224,324-326,393,394, 395,398,401-405,407,410-412,627, 742 against Herpes simplex virus 17:146 against HIV-1 30:398 against HIV-2 17:146;30:398
1037
against HSV 30:401 against HSV-1 30:401 against plant virus infection 30:412 against sandfly fever sicilian virus (SFSV) 30:410 in cell cultures 30:394 in mouse models 30:405 in vitro 30:401,404,405 of (-)-aristeromycin 10:609 of (+)-C-2'-ara-fluoroguanosine 10:609 of 2-amino oxetanocin-A 10:620,621 of 3',4-O-dimethylcedrusin 22:361 of 3'-azido-3'-deoxythymidine 10:585 of aciclovir (9-[2-hydroxyethoxy)methyl] guanine 10:585 of allicin 23:473 of Astragalus brachycentrus 30:405 of,4stragalus echianaeformis 30:405 of Astragalus membranaceus 27:482 of carbocyclic oxetanocin A and G 10:620,621 of carbovir 10:608,609 of carrageenans 30:410 of cationic polysaccharide (PS) 30:402 of D-2'-deoxycarbocyclic guanosine 10:608,609 of defensins 23:346 of dextran sulphate 30:410 of didemnins 10:253,254 of eudistomin E 23:268 of flavonoids 17:145;22:307 of fucoidan 30:410 of Hernandia perforatum 30:407,627 of Ichyroclineflaccida 30:401 ofimidazole analogues 5:566 of lignans 5:461 of mannans 30:402 of marine organisms 5:359,364 ofmycalamide A 5:366
of Nothogeniafastigiata 30:404 of OGs 25:114 of oleanolic acid derivatives 17:135 ofoxetanocin A 10:608,619,620 of oxetanocin G 10:619,620 of pentosan polysulphate 30:410 of Podophyllum extracts 26:169 of polyphenols 28:257,293; 30:224 of polysaccharides 30:393,395 of quinones 30:324-326 of quinovic acid derivatives 17:134 ofresveratrol 23:531 of saikosaponins 23:512 ofSambucus nigra 30:407 of Saponaria officinalis 30:407 of spermidine 5:563 of Sterculia urens Roxb. 405 of sulphated galactan 30:402 of sulphated polysaccharide (PS) 30:403 of tannic acid 23:395 of Theonella sp. 5:364 of verrucosin 26:228 of xylogalactans 30:402 of yeast mannans 30:412 ofl3-carboline alkaloids 23:233 on infected veto cells 30:410 Antiviral agent 19:351,511;24:474-555; 30:394,399,402,405,408 acyclovir as 24:474,486 cidofovir as 24:486,487 didanosine as 24:474,486,488 forscarnet as 24:486,487 from calcium spirulan as 30:399 fucoidan as 30:405 ganciclovir as 24:474,486 in vitro as 30:408 in vivo testing of as 24:491 lamivudine as 24:488 sorivudine as 24:474,486 stavudin as 24:474,486,488 sulphated phyto-PS as 30:402 trifluridine as 24:487 zalcitabin as 24:474,486,488 zidovudine as 24:474,486,487 Antiviral antibiotic 21:407
1038 Antiviral chemotherapy 30:394 Antiviral compounds 24:492-544 alkaloids 24:527-533 buntenolides 24:521,522 carotenoides 24:533-540 chromones 24:499-503 coumarins 24:499-503 iridoids 24:510-521 lignans 24:503-509 macrolides 24:541-544 marine-derived 24:526-543 N-containing compounds 24:527-533 nucleosides 24:527-533 peptides 24:522,527-533 phenolics 24:503-509 phenyl propanoids 24:503-509 phospholipids 24:521,522 polyacetylenes 24:521,522, 541-544 polysaccharides 24:540,541 prostaglandins 24:541-544 proteins 24:522,527-533 pyrones 24:541-544 quinone 24:503-509,541-544 steroids 24:510-521,533-540 tannins 24:510-521 terpenes 24:510-521 terpenoids 24:533-540 thiophenes 24:521,522 xanthones 24:503-509 Antiviral drugs 30:742 Antiviral effect 23:135;30:627 of [3-glucans 23:135 of hypericin 30:627 mechanism of action of 30:627 Antiviral efficacy 30:408 of natural polysaccharidic-related materials 30:408 of pine cone extract 30:408 Antiviral factor (AVF) 24:524 Antiviral glycopeptide 24:524 meliacin as 24:524 Antiviral microbial-derived compounds 24:544-555 actinomycin D 24:547 ansamycin 24:545-546 aphidicolin 24:549 bleomycins 24:547,548
cardyceptin (3'-deoxyadexosin) 24:547 cytochalasins 24:549 distamycins (pyrrole amidines) 24:546 dounomycin 24:547 doxorubicin 24:547 filipin 24:548 gliotoxin 24:545 mithramycin 24:547 mycophenolic acid 24:549 rifamycin-type macrolides 24:545,546 sinefungin 24:547 toyocamycin 24:547,548 Antiviral polyanionic properties 30:404 Antiviral properties 30:407409 of polymeric carbohydrates 30:409 ofpolysaccharide (PS) 30:407 Antiviral protein 13:655 Antiviral screening 30:411 Antiviral screening assays 24:484,490 in vitro 24:484,490 Antiviral substances 30:394,395 from plant kingdom 30:395 from plants 30:394 Antiviral sulphated polysaccharide (PS) 30:408 Antiviral treatments 30:407 Anti-vitamin activity 9:519 of 25-aza-vitamin D3 9:519 Anti-a-D-mannose antibodies 29:559 against Staphylococcus aureus 29:560 in hormone therapy 29:561 in serological development 29:560 in vaccine production 29:560 Anxiety 30:368 role of serotonin (5-HT) in 30:368 Anxiolytic activity 28:177 of Ginkgo biloba L. 28:177 Aphid antifeedant activity 23:304 ofbrucein B 23:304 ofisobrucein A 23:304 of quassin 23:304
1039 Aphid antifeedants 23:304 quassinoid activity as 23:304 Aphidicolin 24:549 antiviral microbial-derived compound 24:549 API 29:591 effects on cathepsin D 29:591 Apiculture 28:390 acaricides in 28:390 Apigenin (5,7,4'-trihydroxyflavone) 29:572 effects on HIV- 1 protease 29:572 effects on aminopeptidase N 29:577 ~-Apiodionen 28:117 as topoisomerase inhibitor 28:117 [3-Apiodionen 28:117 as topoisomerase inhibitor 28:117 Aplyronines A-C 19:609 cytotoxic activities of 19:609 Aplysillin A 28:697 as thrombin receptor antagonist 28:697 Aplysinopsine 5:410 cytotoxic activity of 5:410 (-)-Aplysistatin 16:705 antineoplastic agent 16:705 Apomorphine-binding sigma receptors 25:538 [~-Apopicoropodophyllin 26:213,214 cytotoxicity of 26:213 immunosuppressive activity of 26:214 Apoplastic fluids 25:400 Apoptic body formation 25:466 Apoptosis 22:444;25:268,269,272;
26:752,922,925,993,1262,1264, 1289;27:86-88;28:175 in cerebellar granulosa cells 25:269 in primary granulosa cells 25:269 in susceptible Burkitts lymphoma (BL) 25:272 in viral infections 24:478-480
ofbilobalide 28:175 of ginkgolide B 28:175 of ginkgolide J 28:175 relation with lipid peroxidation 27:86-88 role of 3-(4,5-dimethylthiazol-2yl)-2,5-diphenyl tetrazolium bromide 28:175 role of cerebellar granule cells 25:268 Apoptosis-inducing activity 23:97 on human leukemia 23:97 Apoptotic bodies 25:469 Apoptotic bodies formation 25:468 Appetite suppression 30:194 due to opioids 30:194 Aprotinine 24:524 as protease inhibitor 24:524 Arabidopsis genes 25:414 mutated 25:414 Arabinosidasic 24:994-998 enzymatic activity 24:995-998 Arabinosyl cobaltoxime 30:449 Arachidonate 5-1ipoxygenase 28:216 Artocarpus flavonoids against 28:216 Arachidonate 5-1ipoxygenase activity 28:216 of artonin E 28:217 of morusin 28:217 Arachidonate oxygenase activity 28:217 Arachidonate-5-1ipoxygenases 29:672 adjusting immune response 29:672 as chemotactic agents 29:672 in B lymphocytes 29:672 in basophils 29:672 m eosinophils 29:672 m macrophages 29:672 m mast cells 29:672 m monocytes 29:672 m polymorphonuclear leukocytes 29:672 inducing cell adhesion with 29:672 origin of 29:672 Arachidonic acid 25:66;30:192,225,594 inhibition of 25:66 leukotrienes from 30:225
1040
platelet aggregation induced by 594 Arachidonic acid induced edema 25:46 inhibition of 25:47 Archaebacteria metabolism 25:939 Arctigenin 26:241 as PAF-induced inhibitor 26:241 Arctigenin methyl ether 26:241 as PAF-induced inhibitor 26:241 Arcyriaoxocin A 29:227 against human cancer cells 29:229 against protein kinases 29:229 biological activity of 29:229 for anticancer drugs 29:229 mode of action of 29:229 Ardisia colorata 30:161 cytotoxic activity of 30:161 effect on FM3A cells 30:161 Areca II-5-C (tannin) 29:578 effects on ACE 29:578 Arenarone 5:438 cytotoxic activity of 5:438 Arenavirus replication 30:412 inhibitory effect on 30:412 Arg-D-Trp-NmetPhe-D-Trp-Met-NH2 27:799 as anticancer peptide 27:799 Arisaema heterophyllum B. 22:512 for epilepsy 22:512 (-)-Aristeromycin 10:609 antiviral activity of 10:609 Aromatase inhibitor 28:16,17 albanol A as 28:17 broussoflavonol F as 28:17 broussonin A as 28:16 demethylmoracin I as 28:18 Aromatic L-amino acid decarboxylase (AADC) 30:370,380 activity in metabolic pathways 30:380 Arrow poisons 12:233 ARS2 25:435,451;30:776 antitumor activity of 25:438,451; 30:776 effect on enzyme hydrolysis 30:777 effect on periodate oxidation 30:777
ARS-2 mediated cellular activation 30:781 Arteminolide 24:457 FPTase inhibition by 24:403-464 drtemisia absinthium 28:425 acaricidal activity of 28:425 against aphids 28:425 as insecticide 28:425 Artemisia montana extracts 27:420 biological activity of 27:420 Arterial thrombosis 30:593 due to platelet aggregation 30:593 Arteriosclerosis 30:55,56,58,70 Ganoderman lucidum in treatment of 56,58 prevention of 30:56 role of natural products in 30:55 use of Laminaria japonica Aresch in 30:56 Artery constriction 30:55 Artery relaxation 30:72 by chalcones 30:72 Arthricular synovial membrane 30:689 inflammation of 30:689 Arthritis 26:50;30:58,193 Ganoderman lucidum in treatment of 30:58 Herniaria hirsuta in 26:50 use of capsaicin in 30:193 Arthropod-borne diseases 28:394 of humans 28:394 of livestock 28:394 zoonotic as 28:394 Articulin acetate 30:734 cytotoxic activity of 30:734 Artobiloxanthone 28:229 biological activity of 28:229 drtocarpus flavones 28:216 5-1ipoxygenase activity of 28:216 Artocarpus flavonoids 28:203,216,220 against arachidonate 5-1ipoxygenase 28:216 against TNF-c~ release 28:220 Artocarpus venenosa 28:202 use against inflammation 28:202 use as folk medicine 28:202 use in malarial fever 28:202
1041
Artonin E 28:201,215,229 as 5-1ipoxygenase inhibitor 28:215 biological activity of 28:229 Arylbenzofuran 28:2262as anti-HIV flavonoids 28:226 Aryltetralins 24:742 as anti-HIV agents 24:742 Ascocorynin 29:266 inhibition of gram-positive bacteria by 29:266 Ascosalipyrrolidinone A 28:148 against antibacterial activity of 28:148 against chloroquine-resistant Plasmodium falciparum 28:148 against Trypanosoma brucei 28:148 against Trypanosoma cruzi 28:148 Asparagus recemosus 22:513 for epilepsy 22:513 Aspartate 30:836 a2-macroglobulin inhibition by 30:836 Aspartic proteases 29:568 as inactive zymogens 29:568 chymosin as 29:568 gastricsin as 29:568 haemoglobinases of Plasmodium falciparum as 29:569 immunodeficiency virus 1 (HIV1) protease as 29:569 in Alzheimer's disease 29:569 non-protein inhibitors of 29:570 overexpression of 29:569 pepsins as 29:568 13-secretase as 29:569 Asperdiol 10:18 activity against lymphocytic leukemia 8:15 growth inhibition of KB, PS and LE Cell lines 8:15 Asperger's syndrome (AS) 30:372,373, 384 form of autism 30:373 Aspergillosis 2:422,425 Aspergillus niger 30:431,739 antibacterial activity against
30:739 antifungal activity against 30:739 Aspirin 30:192,195,594 AA-induced platelet aggregation inhibitor 30:594 as cyclooxygenase enzyme (COX) inhibitor 30:192,594 platelet aggregation role of 30:594 structure-activity relationships of 30:195 Assay 25:373;30:833,835 absorbance in 30:835 chromophoric oligopeptides in 30:835 chromophoric procedure in 30:835 for systemin activity 25:373 of EFE 30:835 of isozymers 30:833 ofLumbricus rubellus 30:833 scattering intensity in 30:835 Assay method 25:100 for hepatoprotective effects 25:100 Asthma 30:70,225 treatment of 30:225 Astragali radix 27:513 activitiy of 27:513 Astragalin (kaempferol-3-O-[3-oglucoside) (flavonol glycoside) 29:578 effects on ACE 29:578 Astragatus brachycentrus 30:405,411 antiviral activity of 30:405 Astragalus echianaeformis 30:405,411 antiviral activity of 30:405 Astragalus L. genus 27:443 biological activity of 27:443 Astragalus membranaceus 27:482 antiviral activity of 27:482 Astragalus root 27:445 medicinal use of 27:445 Astragalus spp. 27:483 activitiy of 27:483 Astringent 5:751,754 Astringent agent 23:642 ofteucrium sp. 23:591
1042
Atherosclerosis 11:335;12:399;22:310; 23:470,766;25:934 ;30:224 development of 23:766 of S-allyl cysteine (SAC) 23:470 role of free radicals in 30:224 Atisane ent- 16a, 17-dihydroxyatisan-3one 29:100 activity in mam-2 assay system 29:100 Atopic dermatitis 30:70 H+,K+-ATPase 21:690,701,702,717,719 inhibitory effect on 21:701,719 ATPase activity 21:137 Atractylon 29:88 activity in TPA, skin-1 assay systems 29:88 Atrial natriuretic factor (ANF) 25:519, 540,547 Atromentin 29:271 against Bacillus subtilis 29:272 antibacterial activity of 29:271 as anticoagulant principle 29:271 Aucubin 29:84 activity in TPA assay system 29:84 Aureolic acid antitumor antibiotics 3:173-206 Autism 30:368,371,374,375 as neurodevelopmental disorder 30:371 brain parts affected by 30:375 etiology of 30:368 genetic component to 30:375 impairments in reciprocal social interaction in 30:368 in dizygotic (DZ) twins 30:371 in monozygotic (MZ) 30:371 incidence of 30:374 pathogenesis of 30:368 prevalence of 30:374 restricted pattem in 30:368 role of amygdala in 30:375 role of serotonin (5-HT) 30:368 stereotyped pattern in 30:368 symptoms of 30:371 with multiple etiologies 30:371 Autistic brain 30:376 neuropathological studies of 30:376
Autistic children 30:375,377 cerebellar hypoplasia in 30:375 signal reception in 30:377 Autistic disorder 30:372 diagnostic criteria for 30:372 Autistic features 30:374 in alcohol consumption 30:374 in congenital cytomegalovirus 30:374 in fragile X syndrome 30:374 in hypothyroidism 30:374 in maternal thalidomide 30:374 m phenylketonuria 30:374 in rubella infections 30:374 m tuberous sclerosis 30:374 Autistic individuals 30:375 Autistic spectrum disorders 30:374 neurochemical pathway of 30:374 Autoimmunodeficiency syndrome 18:908 Autoradiographic imaging 30:377 serotonergic innervations in 30:377 Autotoxic effects 28:537 of NO on tumor cells 28:537 Auxins 17:424 effect on root culture growth 17:424 indoleacetic acid as 7:90 naphthaleneacetic acid as 7:90 Avarol 29:111 activity in CRG bioassay system 29:111 activity in TPA bioassay system 29:111 Avarone 29:111 activity in CRG bioassay system 29:111 activity in TPA bioassay system 29:111 AVD treatment 25:462 2Avenafatua L. 27:215 allelopathic interaction of 27:215 Avena sativa 27:216 allelopathic interaction of 27:216
1043
Avena strigosa L. 27:215 allelopathic interaction of 27:214-218 Avermectin 12:709 biological activity of 12:709 structure-activity relationship of 12:8 Avermectin B~ 12:9 insecticidal activity of 12:9 Avermectin B ~ 1:463-465 synthesis of 1:463-465 Avian hemoglobin 5:849 allosteric regulator binding sites 5:849 Avidinphosphatase assay 4:284 Axon terminals 21:7,9,16 Azadirachta indica oil 28:388,395 against bee mites 28:387 against blood sucking ticks 28:395 Azadirachtin 30:696 Azocasein method 30:841 for proteolytic activity 30:841
B cell proliferation 25:273 effect of prehispanolone on 25:273 Baccharis anomala D.C. 750 microsomal activation by 30:750 Baccharis articulata 30.706,708,723, 743,744,750 as antidiabetic 30:706 as decoctions 30:706 as infusions 30:706 in treatment of rheumatism 30:744 in ulcers 30:744 inhibition of viral infectivity by 30:743 Baccharis boliviensis 30:711,712,730, 742 trypanocidal effect of 30:742 Baccharis conferta 30.'704,740,748 against Escherichia coli 30:740 antibacterial activity against Micrococcus luteus 30:740 as laxative 30:705 for stimulating urination 30:705
in treatment of baldness 30:705 in treatment of gastrointestinal illnesses 30:748 in treatment of insect bites 30:705 in treatment of stomach aches 30:704 triterpenoid oleanoic acid methyl ester from 30:740 Baccharis coridifolia 30.705,717,719, 733,751 as anti-inflammatory agent 30:705 in toxic disease 30:751 in treatment of horse's external parasites 30:705 to treat horse's distemper 30:705 toxins from 30:751 Baccharis crispa 30.722,723,739,743, 744,745,750 antibacterial activity against 30:739 antifungal activity against 30:739 essential oil from 30:722 in treatment of liver diseases 30:744 phytotherapeutic drugs from 30:750 Baccharis gaudichaudiana 30:706,734 as antidiabetic material 30:706 as decoction 30:706 as infusion 30:706 in P-388 lymphocytic leukemia cells 30:734 Baccharis genistelloides 30.706,711, 720,733,739,740,743,744,746,748, 749,750 against HSV-1 and VSV 30:743 against Staphylococcus aureus 30:739 anti-inflammatory constituents from 30:746 against Candida albicans 30:739 against gram-positive bacteria 30:739 antimicrobial activity of 30:740 antimutagen constituents from 30:733
1044 as anti-inflammatory material 30:750 as antithermic 30:706 effects on bile duct 30:750 effects on bone marrow 30:750 effects on cardiac function 30:750 effects on liver 30:750 effects on pancreas 30:750 effects on serum lipids 30:750 in anaemia 30:706 in diabetes 30:706 in diarrhoea 30:706 in digestive disorders 30:706 in indigestion 30:706 in inflammation 30:706 in intestinal worms 30:706 in leprosy 30:706 in liver disorders 30:706,733,749 in malaria 30:706 m rheumatism 30:733 m sore throat 30:706 m tonisillitis 30:706 m ulcers 30:706 m urinary disorder 30:706 [3-sitosterol from 30:720 structure-activity relationship of 30:733 use in liver diseases 30:749 use in wounds 30:744 Baccharis genus 30:707,733,738 antibacterial activity of 30:738 antifungal activity of 30:738 Baccharis glutinosa 30:704,739 antimicrobial activity of 30:739 as contraceptive 30:704 for digestive disorders 30:704 for gynecological disorders 30:704 for skin diseases 30:704 in treatment of infectious diseases 30:739 in weight reduction 30:704 to clean wounds 30:704 to treat scalp diseases 30:704 Baccharis grisebachii 30.'705,730,733, 739,745 for decoctions 30:705 for poultices 30:705
for wound healing 30:705 inhibitory activity of 30:745 Baccharis L. 30:704 biological activities of 30:704 traditional uses of 30:704 Baccharis medullosa 30.'712,744 as anti-inflammatory material 30:744 Baccharis megapotamica 30:717,736, 751 activity against P-388 leukemia 30:736 against human carcinoma 30:736 as cytotoxic agents 30:717 toxins from 30:751 verrucarins from 30:717 Baccharis multiflora 30.'705,713 against catarrhs 30:705 as infusion 30:705 Baccharis notosergilla 30.705,739,740, 742,743 against gram-positive organisms 30:740 against Trypanosoma cruzi 30:742 antibacterial activity of 30:739, 740 antifungal activity of 30:739 as digestive agent 30:705 as diuretic 30:705 essential oil of 30:740 in folk medicine 30:705 Baccharis paniculata 30:710,712,731, 740 against phytopathogenic fungi 30:740 for antifungal activity against human pathogens from 30:740 Baccharis rhetinoides 30.'746 anti-inflammatory flavonoids from 30:746 Baccharis rubricaulis 30:706 for treating mucous ailments 30:706 Baccharis rufescens 30:723,744 as anti-inflammatory 30:744 Baccharis salicifolia 30.'705,707,718, 721,722,731,732
1045 for diarrhoea 30:705 for dysentery 30:705 for inflammation 30:705 Baccharis sarothroides 30.'705,710,733 inhibitory activity against human carcinoma 30:733 Baccharis serraefolia 30:705,720,739, 748 against gram-positive organisms 30:739 mechanism of action of 30:748 phytol from 30:720 spasmolytic action of 30:748 to treat diarrhoea 30:705 use in gastrointestinal illnesses 30:705 Baccharis spp. 30:707,711,737,740, 741,750 antineoplastic activity of 30:737 assay-guided fractionation of 30:737 for preparation of phytotherapeuticdrugs 30:750 toxicological evaluation of 30:750 Baccharis tricuneata 30.'706,708,719 for diabetes from 30:706 for skin infections 30:706 Baccharis trimera 30:706 as antithermic agent 30:706 for digestive disorders 30:706 for liver disorders 30:706 use in urinary diseases 30:706 Baccharis trinervis 30:705,725,743 against human immunodeficiency virus 30:743 antiviral activity of 30:743 for gastrointestinal disorders 30:705 in dizziness 30:705 in MT-2 infected cells 30:743 in treatment of edema 30:705 in treatment of high fever 30:705 in treatment of muscle cramps 30:705 in treatment of sores 30:705 in treatment of typhoid fever 30:705
inhibition of HSV-1 30:743 trimethoxyflavone) from 30:725 Baccharis triptera Mart 30:749 in gastrointestinal disorders 30:749 in gastrointestinal hyperactivity 30:749 Baccharis tucumanensis 30.705,733, 744 anti-inflammatory action of 30:745 as abortive 30:705 extract of 30:733 in carrageenan foot edema test 30:745 role in croton oil induced mouse 30:745 Baccharis vaccinoides 30:705,710,739 against Candida albicans 30:739 against Staphylococcus aureus 30:739 antimicrobial activity in vitro 30:739 for gastrointestinal disorders 30:705 Bacillus subtilis 30:629,693,738 antifiangal activity against 30:738 caffeic acid inhibition by 30:225 of drummondins A-C 30:629 ofphloroglucinols 30:629 role of 30:225 Bacopa monnieri L. 22:513 for epilepsy 22:513 Bacterial effects 30:152 of Streptococcus mutans 30:152 Bacterial growth inhibitors 17:101 Bacterial hydrolysis 30:305 of sugar 30:305 Bacterial infections 30:408 Bacterial origin 28:434 acaricidal agents of 28:434 Bacterial reverse mutation test 27:303 Bactericidal effect 26:1095 of HMTP on Sacchromyces epidermidis 26:1095 Bactericidal properties 21:225 Bactericidal/permeability-increasing protein 27:807
1046
Bactericides 28:390 used of essential oil 28:415,390 Bacterioruberin 30:523 as cell membrane stabilisers 30:523 Bactobolin 16:3 antibacterial activity of 16:3 antitumor antibiotic 16:3 Bahiensol 29:253 antimicrobial activity of 29:253 Baicalein 27:435;30:55,69-72,288 anti-inflammatory actions of 30:72 as anti-allergic 30:71,72 biological activity of 27:435 inhibitory action of 30:70 Baicalein (5,6,7-trihydroxyflavone) 29:572,581 effects on HIV- 1 protease 29:572,581 effects on MMP 29:581 Baicalein (flavone) 29:584 effects on LELA 29:584 BALB/c mice 28:534;30:592 epidermal cell culture of 30:592 Meth A sarcoma in 28:534 Balsamodendron sp. 22:513 for epilepsy 22:513 BAP (6-benzylaminopurine) 7:90,9 as cytokinin 7:90,94 Barbatosides A 26:56 analgesic activity of 26:56 as anti-inflammatory agent 26:32 Barbatosides B 26:56 analgesic activity of 26:56 as anti-inflammatory agent 26:32 Barbiturates 25:528 Barceloncic acids 24:450 as human FPTase inhibitors 24:450 structures of 24:450 Barringtonia recemosa 22:514 for epilepsy 22:514 Basidiomycetous fungus 30:403 in folk medicine 30:403 mode of antiviral activity of 30:403 Basilicum polystachyon 22:514 for epilepsy 22:519
Batzella sponge 28:685 against Candida albicans 28:686 antifungal activity of 28:686 Bavachalcone 28:228 biological activity of 28:228 Bayogenin 7:432 molluscicidal activity of 7:432 B-cell leukaemia 21:137 BCG/LPS induced hepatotoxicity 25:471 BE-13793C 12:366,370,396 antitumor activity of 12:396 topoisomerase I and II inhibitors of 12:370 Behavioral dysfunction 30:368 effect of serotonergic neurotransmission on 30:368 Benincasa cerifera savi 22:514 for epilepsy 22:514 Benincasa hispida 22:513 for epilepsy 22:513 Benthiozepines 25:534 diltiazem as 25:534 Benz [a] anthracene antibiotics antibacterial activity of 11:134 antitumor activity of 11:134 Benzaldehyde 28:406 acaricidal properties of 28:406 Benzazepines 25:534 Benzo [a] pyrene 7:8 carcinogenicity of 7:8 Benzo [c]phenanthridine alkaloids (QBA) 27:819 biological activities of 27:178 Benzodiazepine receptors 22:26 Benzodiazepines 22:508,666 Benzofuranoid terphenyls 29:279 antifeedant activity of 29:282 as 5-LOX inhibitor 29:280 as antioxidative component 29:281 effect on DNA, RNA, protein synthesis 29:281 in antibacterial assay 29:281 Benzoxazinoids 27:211 biological activity of 27:211 Benzoxazinone acetal glucosides 27:224,225 biological role of 27:224,225
1047 Benzoxazinones 27:185-225 biological activity of 27:185-225 biological role of 27:224 defoxification of 27:218-222 effects on animal organisms 27:212-214 Benzyl benzoate 28:416 against Psoroptes 28:416 against Sarcoptes mites 28:416 against Sarcoptes scabiei 28:416 effectiveness of 28:416 in mange control 28:416 Benzylcarbamate prodrug HMR1826 21:176,177 preclinical development of 21:176,177 Benzylisoquinoline alkaloids 24:895-897 inhibitory effect on tube formation 24:895-897 Bersama abyssinica 22:514 for epilepsy 22:514 Betulinic acid 28:17,40,62 anti-microbial activity of 28:62 cytotoxic activity of 28:17 Betulinic acid (lupane triterpene) 29:571,574 inhibition of Candida albicans aspartic protease 29:571 inhibition of HIV- 1 protease 29:571 Betulinic acid (lupane triterpene) 29:578 effects on aminopeptidase N 29:578 effects on HIV- 1 protease 29:574 Beyerane ent-3~-Hydroxy- 15-beyeren2-one 29:100 activity in EBV assay system 29:100 Bgt A 21:750-754 clinical trials of 21:754 pharmacological study of 21:748,752-754 of BgtA 21:750-754 Bicuculline 26:868
Bicyclic phloeodictine B 28:688 antibacterial activity of 28:688 cytotoxic activity of 28:688 Bicyclomycin 12:63 antibiotic activity of 12:63 antimicrobial activity of 12:41 toxicity of 12:63 Biflavonoids 30:207 antinocicieptive effect of 30:207 BH cell bioassay 29:33-38 abutasterone activity in 29:34 24-epi-abutasterone activity in 29:36 ajugalactone activity in 29:34 ajugasterones activity in 29:34 amarasterone A activity in 29:34 atrotosterones activity in 29:34 bombycosterol activity in 29:34 calonysterone activity in 29:34 canescesterone activity in 29:34 castasterone activity in 29:34 24-epi-castasterone activity in 29:36 cheilanthone B activity in 29:34 cyasterones activity in 29:34 dacryhainansterone activity in 29:34 2-dansyl-20-hydroxyecdysone activity in 29:34 22-dehydro- 12-hydroxycyasterone activity in 29:34 22-dehydro- 12-hydroxynorsengosterone activity in 29:34
22-dehydro-20-iso-ecdysone activity in 29:35 3-dehydro-2-deoxyecdysone: (silenosterone) activity in 29:34 3-dehydro-2-deoxyecdysone 22acetate activity in 29:34
2-dehydro-3-epi-20-hydroxy-
ecdysone activity in 29:34 24(28)-dehydroamarasterone B activity in 29:34 24(28)-dehydromakisterone A activity in 29:35 25 (25 )-de hydropre cya sterone activity in 29:35 2-dehydroshidasterone-22glucoside activity in 29:35
1048 14-dehydroshidasterone activity in 29:35 14-deoxy( 1413-H)-20-hydroxyecdysone activity in 29:35 3-deoxy- 113,20-dihydroxy ecdysone activityin 29:35 (20R)22-deoxy-20,21-deoxyecdysone activity in 29:35 2-deoxy-20,26-dihydroxyecdysone activity in 29:35 22-deoxy-20-hydroxyecdysone (taxisterone) activity in 29:35 2-deoxy-20-hydroxyecdysone 22benzoate activity in 29:35 (14a-H) 14-deoxy-25-hydroxydacryhainansterone activity in 29:35 2-deoxyecdysone-25-glucoside activity in 29:35 2-deoxyecdysone-3,22-diacetate activity in 29:35 25-deoxyecdysone activity in 29:35 (5 ot-H)2-deoxyintegristerone A activity in 29:35 5-deoxykaladasterone activity in 29:35 2-deoxypolypodine B 3-glucoside activity in 29:35 25,26-didehydroponasterone A activity in 29:35 2,22-dideoxy-20-hydroxyecdysone activityin 29:35 (5 [3-H)-dihydrorubrosterone 29:35 dihydrorubrosterone 17-acetate activity in 29:35 dihyropoststerone tribenzoate activity in 29:35 (22S)20-(2,2'-dimethylfuranyl) ecdysone activity in 29:35 ecdysone 2,3-acetonide activity in 29:36 ecdysone 22-hemisuccinate activity in 29:36 ecdysone 6-carboxymethyloxime activity in 29:36 3-epi-22-iso-ecdysone activity in
29:36 20-iso-22-epi-ecdysone activity in 29:37 25-fluoropolypodine B activity in 29:36 25-fluoroponasterone B activity in 29:36 for ecdysteroid-like activities 29:33 22,2 3-di-ep i-geradiastero ne activity in 29:35 geradiasterone activity in 29:36 28-homobrassinolide activity in 29:36 iso-homobrassinolide activity in 29:37 613-hydroxy-20-hydroxyecdysone activity in 29:36 513-hydroxy-25,26-didehydroponasterone A activity in 29:36 513-hydroxyabutasterone activity in 29:36 25-hydroxyatrotosterone B activity in 29:36 3-epi-20-hydroxyecdysone (coronatasterone) activity in 29:36 20-hydroxyecdysone 22-benzoate activity in 29"" 20-hydroxyecdysone 22hemisuccinate activity in 29:36 20-hydroxyecdysone 2-13-Dglucopyranoside activity in 29:36 20-hydroxyecdysone 3~-Dxylopyranoside activity in 29:36 20-hydroxyecdysone 6-carboxymethyloxime activity in 29:36 (5ct-H)20-hydroxyecdysone activity in 29:36 14-epi-20-hydroxyecdysone activity in 29:36 26-hydroxypolypodine B activity in 29:36 513-hydroxystachysterone C activity in 29:36 inokosterone 26-hemisuccinate
1049 integristerone A activity in 29:37 (25 R/R) inokosterone-20hydroxy-ecdysone activity in 29:36 1-epi-integristerone A activity in 29:36 isostachysterone C activity in 29:37 kaladasterone activity in 29:37 5c~-ketodiol activity in 29:37 limnantheoside C activity in 29:37 24-epi-makisterone A activity in 29:36 14-methyl- 12-en- 15,20dihydroxy-ecdysone activity in 29:37 14-methyl-12-en-shidasterone activity in 29:37 24-methylecdysone (20-deoxymakisterone A) activity in 29:37 muristerone A activity in 29:37 29-norcyasterone activity in 29:37 29-norsengosterone activity in 29:37 paxillosterone 20,22-p-hydroxybenzylene acetal activity in 29:37 pinnatasterone activity in 29:37 podecdysone B activity in 29:37 polypodine B activity in 29:37 polyporusterone B activity in 29:37 ponasterone A 22-hemisuccinate activity in 29:37 ponasterone A 3[3-D-xylopyranoside activity in 29:37 ponasterone A 6-carboxymethyloxine activity in 29:37 ponasterone A dimer activity in 29:37 poststerone 20-dansylhydrazine activity in 29:37 punisterone activity in 29:37 rapisterones activity in 29:37 rubrosterone activity in 29:37
sengosterone activity in 29:37 shidasterone activity in 29:37 sidisterone activity in 29:37 silenoside A (20-hydroxyecdysone 22-galactoside) activity in 29:37 silenoside C (integristerone A 22galactoside) activity in 29:38 silenoside D (20-hydroxyecdysone3-galactoside) activity in 29:38 stachysterones activity in 29:38 2[~,313,20S,25-tetrahydroxy-25fluoro-5 [~-cholest-8,14-dien-6one activity in 29:38 2c~,3ot,22S,25-tetrahydroxy-5 c~cholestan-6-one activity in 29:38 213,3[3,6or-trihydro xy- 5 [3cholestane activity in 29:38 mrkesterone 11 c~-acetate activity in 29:38 turkesterone 11 ot-arachidate activity in 29:38 turkesterone 11 c~-butanoate activity in 29:38 turkesterone 11 c~-decanoate activity in 29:38 turkesterone 11 ot-hexanoate activity in 29:38 turkesterone 11 ~-laurate activity in 29:38 turkesterone 11 ot-myristate activity in 29:38 turkesterone-2,11 c~-diacetate activity in 29:38 mrkesterone-2,22ot-diacetate activity in 29:38 viticosterone E activity in 29:38 Binding assay 30:494 of calf-thymus vitamin D receptor 30:494 Binding bioactivity 30:813 of [Tyr)Me)2-Phe] peptides 30:813 of d-Tyr(Me)2-d-Phe-G-V-VNH2 30:813 of d-Tyr(Me)2-d-Phe-NH2
1050
30:813 of d-Tyr(Me)2-Phe-G-V-V-NHE 30:813 of d-Tyr(Me)z-Phe-NHz 30:813 of Tyr(Me)2-d-Phe-G-V-V-NH2 30:813 of Tyr(Me)E-d-Phe-NH2 30:813 of Tyr(Me)2-Phe-G-V-V-NH2 30:813 of Tyr(Me)2-Phe-NH2 30:813 Bioactive 3-deoxy-ulosonic acids 30:419 recent advances in 30:419 Bioactive compounds 24:954-956 of EMIBD 24:954-956 Bioactive compounds 28:3,4,9,16,22 from Broussonetia genus 28:3 from Broussonetia kazinoki 28:4,9 from Broussonetia papyrifera 28:16,22 Bioactive constituents 23:552 of monotoideae 23:552 Bioactive constituents 30:559 of genus Hernandia 30:559 Bioactive diterpenes 24:175-213 Bioactive metabolites 21:364;23:185 from Indo-Pacific marine invertebrates 21:251 from soil-borne fungi 21:181 of symbiotic marine microorganisms 23:185 structure-activity relationships of 21:251 Bioactive monoterpenoids 28:426 carvacrol as 28:426 carvomenthenol as 28:426 carvone as 28:426 citronellol as 28:426 eugenol as 28:426 geraniol as 28:426 perillyl alcohol as 28:426 4-terpineol as 28:426 thymol as 28:426 Bioactive natural products 23:488 from Chinese medicinal plants 21:729 Chinese medicinal plants 21:729
from bioactive natural products 21:729 Bioactive saponins 21:633 from plants 21:633 Licochalcone A 21:744 bioactivity of 21:744 Bioactive secondary melabolites 23:185-231 from Okinawan sponges 23:185-231 from tunicates 23:185-231 Bioactive terpenes 24:175-213 Bioactive triterpenes 30:635 from celastraceae 30:635 Bioactivity 21:744;23:335;24:933972;25:668;26:909, 911-914,926;27:348;30:233,516,520 8'-hydroxyabscisic acid 27:349 bioactivity of 27:348 of 8'-hydroxyabscisic acid 27:349 of carotenoids 30:516,520 of cocumarins 23:335 of EMIBD 24:954-956 ofendophytic fungi 24:933-972 of HIRE 24:951-954 of labiatae flavonoids 30:233 oflicochalcone A 21:744 of nitric oxide 26:926 of phenolic compounds 25:668 Bioantimutagenic 21:641 KB Bioassay 2:404,405,9:230,231, 238,220-222 Bioassay-directed fractionation 30:157, 591 of Ozoroa insignis 30:157 use of chromatographic techniques in 30:591 Bioassays 24:863-869;30:801 allelopathy 24:867 anti-feedant 24:866 anti-fungal green house 24:864 anti-inflammatory 24:869 anti-microbial 24:863,864 antioxidant 24:868 brine shrimp 24:864,865 caterpillar data 24:866 corn earworm 24:865 cytotoxicity 24:867
1051 forest Tent caterpillar 24:865 Gypsy moth 24:865 herbicidal 24:867 insecticidal 24:866 mosquitocidal 24:864 neuraticidal 24:866,867 statistical analysis of 24:866 tobacco hornworm 24:865 topoisomerase inhibitory 24:867, 868 Bioavailability 23:776;27:312,314 of nutrients 27:312,314 of phenolic antioxidants 23:746, 775 Biochemical assays 30:226 activity of natural polyphenols in 30:226 Biocidal activity 21:598 Biocontrol activity 21:187 Biocontrol agents 21:181 Biogenesis 26:141,142,313,314,405, 465,552,1054 for Nb-C(21 ) secocuran alkaloids 26:1054 of sclareol 26:405 of diterpenes 26:465 of F r a x i n u s o r n u s 26:313,314 of secologanin type alkaloids 26:142 of some iridoids 26:141 of the resveratrol oligomers 26:552 Biogenetic precursors 30:622 of xanthones 30:622 Biogenic amines 15:328 Bioinsecticides 15:381 Biological action 24:875 as anti-angiogenesis 24:875 as anti-hyperglycemic 24:875 as anti-inflammation 24:875 as anti-proliferation 24:875 in blood glucose regulation 24:875 in blood vessel relaxation 24:875 in cardiotonicity 24:875 in neuromuscular blocking 24:875 in smooth muscle relaxation 24:875
Biological activities 21:132,148,162, 223,236,238,263,265,269,284,297, 366,388,390,410,419,421,431,571, 578,591,598,601,603,620,694 ;23:63, 93,95,108,111,129,126,107-152,153, 158,179,267,271,285,395-453, 455-485,491,497,642-643 ;739;24:25, 799,845 ;27:178,377,431,421,443, 693,778,801,924 ;24:353-376; 27:185-225,332,659;28:109,212,228, 229,340;29:743 ;30:4,26,172,175, 200,224,303,310,395,404,483,484, 485,495,496,497,499,562,588,603, 637,831,840,843, acaricidal 24:799 allelopathic 24:845 anti-bacterial 24:25 antibiotic 24:799 anti-feedant 24:845 anti-fungal 24:25,799 anti-inflammatory 24:799 antimalarial 30:561 anti-microbial 24:845 anti-oxidant 24:845 annoxidant 30:561 antiplatelet aggregation 30:560 ann-secretory 24:799 ann-serotonergic 24:799 ann-tumor 24:845 biological activity of 21:535 biological activity of 21:571-580, 573 chirality in 7:3-28 choleretic 24:799 cytotoxic 24:799,845 cytotoxic 30:560,561 Decumbenine B 21:735 Essential oils 21:571-580,573 herbicidal 24:799 H e r n a n d i a species 30:588 m black-sugar 27:409,410 m fat cell 27:393 m human osteosarcoma j 30:497 m human osteosarcoma 2 30:497 in red wine 27:430 m vivo 30:499 inhibition of enzyme 24:845 insecticidal 24:25,799,845 isolation of 4:243
1052 molluscicidal 24:799 of (-)-selin-11-en-4a-ol 14:450, 451 of (+)-caffeic acid 27:421 of (+)-chlorogenic acid 27:421 of (+)-compactin 11:335,336 of (+)-mevinolin 11:335,336 of (EFEa) 30:831 of ~-glucans 23:107,111,115,135 of 14a-hydroxy-MFA 28:340 of 1-methoxyficifolinol 28:229 of 1-methoxyphaseollidin 28:229 of lc~,25-(OH)2D 30:495 of lcx,25(OH)ED analogues 30:495 of 1cx,25(OH)2D3 30:496 of lc~,25(OH)2D4 30:499 of 3'-(7,y-dimethylallyl)kievitone 28:228 of 3-hydroxyglabrol 28:228 of 3-hydroxyparatocharpin Cg 28:228 of 3-O-methylgancaonin P 28:229 of 4'-O-methylglabridin 28:229 of 6-prenyleriodictyol 28:229 of 6-prenylnaringenin 28:229 of 8-(y,7-dimethylallyl)wighteone 28:228 of 8-prenyleriodictyol 28:229 of abscisic acid 27:331,352 of acetyl-N-Ser-Asp-Lys-Pro 27:806 of agrimoniin 23:398 of agrimoniin 23:398 ofalbanin D 28:229 ofalbanin F 28:230 ofalbanol A 28:230 ofalbanol B 28:229 of alvaxanthone 28:229 of amicoumacins 15:410-412 of Angelica shikokiana 27:429 ofangustone B 28:228 of antiarone B 28:229 of antiarone F 28:229 of antiarone G 28:229 of antiarone H 28:229 of antiarone I 28:229
of antiarone J 28:229 of Artemisia montana extracts 27:420 of Artemisiae herba 27:413 of artobiloxanthone 28:229 ofartonin E 28:229 ofastragalus L. genus 27:443 of avermectins 12:7-9 ofbaciphelacin 15:409,410 of baicalein 27:433,435 of balanol 27:869 of bavachalcone 28:228 of Benzo[c]phenanthridine alkaloids (QBA) 27:819 ofbenzoxazinoids 27:211 ofbenzoxazinones 27:185-225 of bis-indolyl maleimides 12:384-399,133,91 of bombesin 27:797 of bombsin 27:797 ofbroussochalcone I3 28:228 ofbroussoflavonol B 28:229 ofbroussoflavonol C 28:229 ofbroussoflavonol E 28:230 of Bupleurum rigidum 27:693 ofBupleurum rigidum L. 27:659 of capsaicin 30:200 of chitosan 27:404 of cholesterol oxides 24:351-398 of cudraphenone B 28:230 of cudraphenone D 28:230 of cycloartobiloxanthone 28:230 of decumbenine B 21:735 of dehydroglyasperin C 28:228 of discodermolide 30:4 of dynorphins 27:801 of echinatin 28:228 of edudiol 28:228 of EFE 30:840 of endorphins 27:801 of endotoxin-induced 27:435 of enkephalins 27:801 of erythrinin B 28:229 of erythromycin 13:155-185 of Escherichia coli 30:843 of essential oil 21:571 of essential oils 21:571-580,573 of flavonoids 23:739 of flavonoids 27:425
1053 offlavonoids 27:431 of formaononetin 28:228 of free fatty acid 27:404 of fungal [3-glucans 23:108,111, 126 of fungal [3-glucans 23:108,111, 126 ofgancaoinin S 28:228 ofgancaonm C 28:228 of gancaonm E 28:228 of gancaonln G 28:228 of gancaonm H 28:228 of gancaonm I 28:228 of gancaonm O 28:228 of gancaomn P 28:228 of gancaonm Q 28:228 of gancaonm R 28:228 of gancaonm U 28:228 of gancaonm V 28:228 ofgancaonln Y 28:228 of garlic 23:468 of Geranii herba 27:413 of Geranii herba 27:415 of Ginkgo biloba 30:172 ofginsenoside Rgl 27:424 of glabranin 28:228 of glabranine 28:228 of glabrene 28:228 of glabridin 28:228 ofglabrocoumarone A 28:229 of glabrol 28:228 of glisoflavanone 28:228 ofglyasperin A 28:228 ofglyasperin B 28:228 ofglyasperin C 28:228 ofglyasperin D 28:228 ofglyasperin J 28:228 ofglyasperin K 28:228 of glycycoumarin 28:228 ofglycyrdione A 28:228 of glycyrin 28:228 of glycyrol 28:228 ofglyinflanin A 28:228 of green tea 27:417,420 of Hernandia nymphaeifolia 30:562 of Hernandia species 30:562 of Hernandia voyronii 30:562 of heterophyllin 28:230
ofhispaglabridin A 28:228 of hyperlipdaemia 27:405 of indolo [2,3-a] carbazole alkaloids 12:384-399 ofintermedeol 14:450,451 of isoalvaxanthone 28:230 ofisoderrone 28:228 of isoglycyrol 28:228 of isoliquiritigenin 28:228 of ivermectin 12:8,9 ofkanzonol B 28:229 ofkanzonol G 28:229 ofkanzonol H 28:229 ofkanzonol P 28:229 ofkanzonol R 28:229 ofkanzonol S 28:229 ofkanzonol U 28:229 ofkanzonol V 28:229 ofkanzonol W 28:229 ofkanzonol X 28:229 ofkanzonol Y 28:229 ofkazinol B 28:230 ofkazinol E 28:230 ofkazinol F 28:230 ofkazinol N 28:230 of KB-1 28:229 of KB-3 28:229 of kumatakenin 28:229 of kuwanon 28:212 ofkuwanon C 28:230 ofkuwanon G 28:230 ofkuwanon H 28:212 ofkuwanon M 28:212 ofkuwanon R 28:230 oflicochalcone A 28:229 oflicochalcone B 28:229 of licoflavonol 28:229 of licoisoflavanone 28:229 oflicoisoflavone A 28:229 oflicoisoflavone B 28:229 of licorice 27:425 of licoricidin 28:229 of licoricone 28:229 oflicorisoflavan A 28:229 of lipogenesis 27:393 of lipolysis 27:393 ofmacarangaflavanone B 28:229 of medicarpin 28:229 of medicinal plants 27:393,405
1054 of microcystins 20:896,897 of monoterpenoid enantiomers 27:377 of montanin C 23:643 ofmoracein B 28:230 ofmoracin C 28:230 of morusin 28:212,230 of morusinol 28:230 of mulberrin 28:230 of mulberrochromene 28:230 of mulberrofuran B 28:230 ofmulberrofuran G 28:212,230 of naringenin 28:229 of natural products 7:3-29; 27:393,405 of natural steroids 30:485 ofneointermedeol 14:450,451 ofnocamycin 14:110 of nodularins 20:896,897 of non-sugar fraction 27:409,410 of norartocarpetin 28:230 of oligomeric compound 27:778 of Oolong tea 27:401 of opioid peptides 27:801 of organosulfar compounds 23:455-485 of organosulfur compounds 23:468 of oxydihydromorusin 28:230 ofparatocarpin L 28:229 of phaseoluteone 28:229 of PI turnover inhibitors 15:461, 462 of pinocembrin 28:229 ofpironetin 30:26 of plasma glucose 27:412 of polyene macrolides 6:261 ofPolygonum sp. 27:405 ofpolyphenols 30:224 ofpolysaccharide (PS) 30:395 of Pseudopterogorgia sp 23:179 of pseudopterosins 23:154,158 of pyranocoumarin 27:429 of quassinoids 23:285-333 of quinones 30:303 of resorcinolic lipids 30:175 of resveratrol 27:430 of rifamycin B 23:93 of rifamycin P 23:95
of rifamycin S 23:94 of saikosaponins 27:693 ofsanggenol C 28:230 ofsanggenol M 28:230 ofsanggenon A 28:212,230 ofsanggenon B 28:230 of sanggenon C 28:212,230 of sanggenon D 28:212 ofsanggenon M 28:230 of saponin 27:859 of Scutellariae radix 27:431 of self-inhibitors 9:222,238 ofsemilicoisoflavone B 28:229 of serum TC 27:420 of serum transaminase 27:415, 417,420,421 of serum triglyceride 27:404 of shinpterocarpin 28:229 ofsigmoidin A 28:229 ofsigmoidin B 28:229 of sorocein F 28:230 of soyasaponins 27:399 of spatane diterpenoids 6:39 of spatol 6:39 of sphingolipids 18:459,460 of Spirulina platensis 30:404 of staturosporine 12:399 ofstilbene derivatives 27:405, 409 of streptolydigin 14:108,109 of tannic acid 23:412 of tannin 23:442;27:413,416 of taxanes 11:4-6 of taxodione 14:667 oftenuifolin B 28:229 of tetracyclic pyridoacridine alkaloids 23:271 of tetrahydro-13-carbolines 23:267 oftetramic acid 14:107-110 of tetramic acid-containing compounds 28:109 ofteucjaponin A 23:642 ofteucjaponin B 23:643 of topozolin 28:229 of triterpenes 30:637 of tyrosine kinase inhibitors 15:447,449 of vitamin D analogues 30:485
1055
of vitamin D2 30:483,484 of vitamin D3 30:483,484 of vitamin D4 30:483,484 of vitamin D5 30:483,484 of vitamin D6 30:483,484 of vitamin D7 30:483,484 of wighteone 28:229 of xenocoumacins 15:408,409 of c~-lapachone 29:743 of 13-glucosidases 27:778 of ~-lapachone 29:743;30:310 spasmogenic 24:799 spasmolytic 24:799;30:561 stimulatory 24:845 trypanosomal 24:799 Biological activity alteration 24:897 by processing 24:897 Biological behaviour 21:161,169 ofgalactose prodrugs 21:161 of glucuronic prodrugs 21:169 Galactose prodrugs 21:161 biological behaviour of 21:161, 169 Glucuronic prodrugs 21:169 Biological control fungi 21:187 antifungal metabolities from 21:187 Galactose prodrugs 21:161 biological behaviour of 21:161 Glucuronic prodrugs 21:169 biological behaviour of 21:161 Biological control 21:182 of soil-born phytopathogens 21:182 biological control of 21:182 Biological effects 21:501,524 Biological evaluation 23:591-648 of Genus teucrium 23:591-648 Biological processes 30:420 ofulosonic acids 30:420 Biological properties 10:241-302;23:93; 28:518,519 of ansamycin antibiotic 23:93 of didemnins 10:241-302 of lipid A 28:519 of lipo-CCK 18:857-863
of lipo-gastrin 18:857-863 Biological response 23:12 Biological response modifiers (BRMs) 25:431,434,452-455 Biological role 27:224,225;30:422 of benzoxazinone acetal glucosides 27:224,225 ofbenzoxazinones 27:185-225 of 3-deoxy ulosonic acids 30:422 Biological significance 24:369 of cholesterol variation number (CVN) 24:351,368,369 biological significance of 24:369 Biological studies 28:35;30:561 of genus Hernandia 30:561 on Licania genus 28:35 Biologically active compounds 17:153 Biologically active constituents 23:662 of celastraceae 23:662 Biologically active diterpenoids 21:689 from Scoparia dulcis 21:689 Biologically active glycolopoprotein complex (G-90) 30:485,826 species of 30:826 Biologically active metabolites 23:649-738 of celastraceae 23:649-738 Biologically active precursor 23:63 ofdamavaricin D 23:63 ofdamavaricin C 23:63 Biomedicine 30:827 Biomineralization 25:335 of heme 25:334 of hemozoin 25:360 -process 25:327 Biorational plant protectants 21:109 alkaloids as 21:109 Bioregulators 2:377-386 studies with 2:377-386 chiral synthesis of 6:537-566 Biotic stress 23:741 Biotoxicity 21:596 Biphenyl ether,4,4'-diallyl-2,3'dihydroxybiphenyl ether 24:861 anti-fungal activity of 24:861 Bipolar disorder 30:369 effect of circadian activity on 369 Bisabolane xanthorrhizol 29:87 activity in COX assaysystem
1056 29:87 activity in iNOS assay system 29:87 Bisabolane: ar-turmerone 29:87 activity in COX assay system 29:87 activity in iNOS assay system 29:87 Bisabolane: f3-turmerone 29:87 activity in COX assay system 29:87 activity in iNOS assay system 29:87 Bisbenzofuranoid terphenyls 29:284 as PEP inhibitors 29:284 in antimicrobial assays 29:284 Bisindolymaleimides 29:230 cell-cycle checkpoint inhibition by 29:230 cyclin-dependent kinase (CDK) inhibition by 29:230 protein kinase C inhibition by 29:230 rebeccamycin as 29:230 staurosporine as 29:230 topoisomerase I mediated DNA cleavage 29:230 15,16-Bisnor- 13-acetoxylabda8(17), 11E-dien- 19-oic acid 29:101 activity in EBV bioassay system 29:101 15,16-Bisnor- 13-hydroxylabda8(17), 11E-dien- 19-oic acid 29:101 activity in EBV bioassay system 29:101 15,16-Bisnor- 13-oxolabda-8(17), 11Edien- 19-oic acid 29:101 activity in EBV bioassay system 29:101 15,16-Bisnor- 13-oxolabda-8(17)-en- 19oic acid 29:102 activity in EBV bioassay system 29:102 14,15-Bisnor-8~-hydroxylabd- 11E-en13-one 29:101 activity in EBV bioassay system 29:101 Black vomit 1:679,680
Black-sugar 27:409,410 biological activity of 27:409,410 Blasticidin 28:127 as antibiotic 28:127 Blastogensis 26:217 inhibitory activity on 26:217 Blastomycosis 22:60 Bleomycins 24:547,548 antiviral microbial-derived compound 24:547,548 Blood chylomicron 30:79 obesity induction 30:79 Blood coagulation 21:670;30:70 role of serine protease in 30:70 role of thrombin in 30:70 Blood coagulation activity 21:670 Blood glucose 30:58 effect of Ganoderman lucidum 30:58 elevation of 30:58 Blood glucose regulation 24:875 as biological action 24:875 Blood glucose regulatory action 24:875-925 of Kampo medicines 24:875-926 Blood pressure activity 21:670 Blood schizontocidal activity 22:152 Blood thrombocytopenia 26:265 Blood vessel contraction 24:875-925 of Kampo medicines 24:875-926 Blood vessel relaxation 24:875-925 as biological action 24:875 of Kampo medicines 24:875-926 Blood vessels 30:410 Blood-brain-barrier (BBB) 786,800,813 Blood-high-viscosity-syndrome 30:839 treatment of 30:839 Bloom-forming cyanobacteria 26:352 Anabaena 26:352 Aphanizomenon 26:352 Cylindrospermopsis 26:352 Lyngbya 26:352 Microcystis 26:352 Nodularia 26:352 Nostoc 26:352
Oscillatoria (Planktothrix) 26:352
Umezakia 26:352 B-lymphocyte 22:259
1057
Boll weevil pheromone 1:693 Bombax malabaricum DC. 22:514 for epilepsy 22:514 Bombesin receptor antagonists 28:221 from Morus species 28:221 ofkuwanon G 28:221 ofkuwanon H 28:221 Bombsin 27:797 biological activity of 27:797 Bone calcium mobilization 30:484 role of vitamin D2 in 30:484 Bone marrow hypoplasia of 26:688 Bone mobilization 30:497 assay for 30:497 in vivo 30.'497 Bone resorbing activity 30:495 of lc~,25(OH)aD2 30:495 of lc~,25(OH)zD4 30:495 of lct,25(OH)2D3 30:495 Bone resorption 21:702 inhibitory activity on 21:720 inhibitory effect on 21:702 Borjatriol 29:102 activity in CTN bioassay system 29:102 [3-Boswellic acid (triterpene) 29:585 effects on leukocyte ELA 29:585 Botanical juvenile hormones 18:498 Bovine brain FPTase activity 24:446 of cylindrols 24:445-447 Bovine papillomavirus type 1 30:406 microbicidal compound against 30:406 Bovine serum albumin (BSA) 30:837, 844 F-II hydrolysis of 30:837 Bowman-B irk protease barley rootlet BBI 29:599 dual function a-amylase/trypsin CM (chloroform-methanol soluble proteins) 29:602 Bowman-Birk serine protease inhibitor proteins 29:598 A-I as 29:598 A-II as 29:598 B-I as 29:598 B-II as 29:598
B-III as 29:598 ATI (alfalfa trypsin inhibitor) as 29:598 BBI-1 as 29:598 BBPIP as 29:598 BTCI as 29:599 C-II as 29:598 CLTI-I as 29:598 CLTI-II as 29:598 CPTIs as 29:599 DATI as 29:598 DE-1 as 29:598 DE-2 as 29:598 DE-3 as 29:598 DE-4 as 29:598 DgTI as 29:598 D-II as 29:598 EBI as 29:598 E-I (PI-I) as 29:598 FBI as 29:599 HGI-III as 29:598 I (ABI-I) as 29:598 I-A, I-B, I-A', II, II', I I-A as 29:598 BPV-4 (Bovine papilloma Virus type 4) 26:761 Bradycardia 30:191,194 as pain mediator 30:192 due to opioids 30:194 Bradykinin 9:296,298 Bradykinin B: receptor 30:203 interaction with ginseng 203 Bradykinin induced edema 25:46 inhibition of 25:46 Bradykinin receptors 21:73 Brain 30:192,383 COX3 enzyme in 30:192 serotonin (5-HT) receptors in 30:383 Brain development 30:375 serotonin (5-HT) 5A receptor in 30:375 Brain enzymes 30:816 resistance to 30:816 Brain membrane synaptosomes 30:814 radioligands from 30:814 Brain neurons 30:371 Brain processes 30:367 role ofserotonin 30:367
1058
Brain stem 30:370 tryptophan hydroxylase (TPH) in 30:370 Bramia monnieri L 22:513 for epilepsy 22:513 Brassica nigra L. 22:514 for epilepsy 22:514 Brassinolide 16:321 antiecdysteroid activity of 16:321 biological activity of 19:245,281 plant growth promoter 16:321 Brassinosteroids 19:473 biological activity of 19:473 Breast cancer 24:933 Brein 30:206 use in inflammatory skin conditions 30:206 Brein (urs-12-ene-3[3,16[3-diol) 29:586 effects on CHY 29:586 Brein 3-O-myristate (urs- 12-ene313,1613-diol 3-O-myristate) (triterpene) 29:586 effects on CHY 29:586 Brein 3-O-palmitate (urs- 12-ene313,1613-diol 3-O-palmitate) (triterpene) 29:586 effects on CHY 29:586 Brevetoxin B4 28:656 as toxin 28:656 from Perna canaliculus 28:656 in shellfish poisoning 28:656 Brevetoxins 21:300,301 Brine shrimp 9:385,387-400;24:864,865 bioassay of 24:864,865 lethality bioassay of 9:385, 387-400 Brine shrimp bioassay 30:733 Brine shrimp toxicity 9:395;24:944-950 ofendophytic fungi 24:944-950 of Goniothalamus giganteus 9:395 Bripiodionen 28:117,118 as human cytomegalovirus protease inhibitors 28:118 cytotoxicity of 28:118 Broad spectrum activity 28:332 of anthelmintics 28:332
Bronchitis 30:58,88 Ganoderman lucidum in treatment of 30:58 Platycodon grandiflorum in treatment of 30:88 Bronchodilators 5:759 in treatment of asthma 5:759 Broncholytic activities 21:633 Broussoaurone A 28:16,17 antioxidant activity of 28:16,17 as cyclooxygenase inhibitor 28:16,17 as neutrophils respiratory burst inhibitor 28:16 as nitric oxide production inhibitor 28:16 as platelet aggregation inhibitor 28:16,17 Broussochalcone B 28:228 biological activity of 28:228 Broussoflavan A 28:16 antioxidant activity of 28:16 as platelet aggregation inhibitor 28:16 Broussoflavonol B 28:226,229 anti-human immunodeficiency virus (HIV) activity of 28:226 biological activity of 28:229 Broussoflavonol C 28:226,229 anti-human immunodeficiency virus (HIV) activity of 28:226 biological activity of 28:229 Broussoflavonol E 28:17,230 as platelet aggregation inhibitor 28:17 biological activity of 28:229 Broussofiavonol F 28:17 antioxidant activity of 28:17 antiproliferative activity of 28:17 as aromatase inhibitor 28:17 as cyclooxygenase inhibitor 28:17 as platelet aggregation inhibitor 28:17 Broussoflavonol G 28:17 antifungal activity of 28:4 antiinflammatory activity of 28:4 antioxidant activity of 28:4,17 antiproliferative activity of 28:17
1059
antispasmodic activity of 28:4 sexual potency of 28:4 Broussonetia papyrifera 28:4,16 anti-cancer activity of 28:4 antifungal activity of 28:4 antioxidant activity of 28:4 diaphoretic activity of 28:4 in dyspepsia 28:4 in pregnancy 28:4 laxative activity of 28:4 Broussonetia zeylanica 28:4,28 aromatase inhibitory substance from 28:4 cytotoxic flavonoids from 28:4 glycosidase inhibitory alkaloids from 28:4 Broussonin A 28:16 antifungal activity of 28:16 as aromatase inhibitor 28:16 Broussonin B 28:16 antifungal activity of 28:16 Bryostatin 19:572 as anticancer drugs 19:550,572 pharmacological aspects of 19:572 Beta-eudesmol 24:883-887 potentiating effects on neuromuscular blocking action 24:883-887 Bt2 cAMP-treated carrot cells 25:490 Bufonis 24:904 inhibition of capillary permeability by 24:905 Bulimia 30:369 effect of circadian activity on 369 Buntenolides 24:521,522 as antiviral compound 24:521, 522 Bunya virus infection 30:410,411 mouse model for 30:411 treatment of 30:411 Bupleuroside III,IV,XII1 25:474 hepatoprotective activity of 25:474 Bupleurum rigidum L. 27:659,693 biological activity of 27:688,693 Burkitt's lymphoma 26:926 Bursehernin 30:568,592 as EBV inhibitor 30:592
4-0-Butanoyl-4'-demethyl podophyllotoxin 24:740,741 cytotoxicity of 24:740 Butea monosperma (Lam.) Kuntze 2:514 for epilepsy 22:514 Butein (chalcone) 29:572 effects on HIV- 1 protease 29:572 Butylidenephthalide 24:890-892 alleviation of cardiovascularinflammation 24:890-892 inhibitory effect on SMCs 24:890-892 Byrsonima crassifolia 24:779,826-835 pharmacological activity of 24:828 C8-Hexanoate 30:27 mitogen responses to 30:27 suppressive effects of 30:27 Ca 2+ channels 25:531;30:194 blockade of 30:194 Ca2+/Calmodulin 25:261 Ca2+/CAM-dependent protein kinases 25:489 Ca2+-ATPase 25:492,493,524,536 Ca2+-ATPase inhibitor 25:536 xanthone a-mangostin as 25:531,536 Ca2+-calmodulin (CAM-dependent protein kinase) 25:261,524 Ca2+-Cam-activated adenylyl cyclase 25:538 Ca-2+CaM-depdendent protein kinase 25:522,544,546,547 Ca2+-channel agonists 28:695 Ianthella basta as 28:695 Ca2+-channel blockers 25:489 Ca2+-channels 25:521 Ca2+-dependent CAM 25:491,540 Ca2+-dependent enzymes 25:517 Ca2+-dependent K + channel 25:534 Ca2+-dependent process 25:487 Ca2+-induced LDL oxidation 25:946 Ca2+-inhibitors 25:487 Ca2+-ionophore A23189 25:487,490, 509
1060 CaZ+-mediated signalling 25:526 Ca2+-mediated signalling targets 25:542 Ca2+-permeable ion channel 25:397 Ca2+-pumping ATPase 25:492 Ca2+-translocating ATPase 25:492 activity of 25:492,496 Ca2+-transporting systems 25:492 Caesalpinia pulcherrima L. for 22:514 Cafestol 29:101 activity in CYP bioassay system 29:101 activity in GSH bioassay system 29:101 activity in GST bioassay system 29:101 activity in skin-6 bioassay system 29:101 from green coffee beans 29:101 (+)-Caffeic acid 27:421 biological activity of 27:421 Caffeic acid (phenylpropanoid) 29:578 effects on ACE 29:578 Caffeine 28:422 acaricidal activity of 28:422 Calcemic effects 30:484,495 of lc~,25(OH)2Dz 30:495 of lot,25(OH)zD3 30:484,495 of lc~,25(OH)zD4 30:495 Calcium antagonistic activity 23:804 of nootkatol 23:804 Calcium effects 12:397 of staurosporine 12:397 Calcium spirulan 30:400,403 structure-activity relationships of 30:403 Calcium uptake inhibitor 28:119 cyclopiazonic acid as 28:119 Calcium/calmodulin-dependent protein kinase 12:389 Calcium-induced contractions 30:748 Calebassine 25:528 as immunosuppressive drug 25:528 Calenduladiol (lup-20(29)-ene-3 [3, 1613-diol) 29:586 effects on CHY 29:586
Calf-thymus vitamin D receptor 30:494 binding assay for 30:494 Calicheamycin 24:934 as anti-cancer agent 24:934 Californian sponge 28:671 antiinflammatory activity of 28:671 antimicrobial activity of 28:671 Calliphora bioassay 29:25 13-acetoxy-14c~-hydroxy-5 [3cholest-7-en-6-one activity in 29:263 as ecdysteroid activity assay 29:25 22-dehydro-25-deoxy-ecdysone activity in 29:26 3-dehydroecdysone activity in 29:26 2-deoxy-20-hydroxy-ecdysone activity in 29:26 22-deoxy-20-hydroxy-ecdysone [taxisterone] activity in 29:26 3-epi-2-deoxy-20-hydroxyecdysone activity in 29:26 25-deoxy-7,8-dihydro-ec dysone activity in 29:26 213,14c~,-dihydroxy-5 c~-cholest-7en-6-one activity in 29:27 3c~,14ct-dihydroxy-5 ot-cholest-7en-6-one activity in 29:27 6-oxo-3 ct, 14a-dihydroxy-5 [3cholenoic acid methyl ester activity in 29:27 3-oxocholest-dihydroxy-cholest4,7-dien-6-one activity in 29:27 313,14c~-4,6,8(14)-triene activity in 29:27 3[3,7e-dihydroxycholest-5-ene activity in 29:27 (2 5R/S) 2 0 ,2 6-dih ydro x yecd yso ne activity in 29:26 20-(2',2'-dimethyl-(22R)- furanyl) ecdysone activity in 29:26 6,24-dioxo-3~,14a-dihydroxy- 5Dchol-7-en-24-dimethylamine activity in 29:27 ecdysone activity in 29:26,28
1061
3 [3-ethoxy- 14c~-hydroxy-5 [3cholest-7-en-6-one activity in 29:26 for Bombyx mori pupae's ecdysone 29:25 for Calliphora erythrocephala 29:25 14(x-hydroxy-3 ~x,5c~cyclocholest- 7-en-6-one activity in 29:27 3-oxo- 14~-hydroxy-5~-cholest- 7en-6-one activity in 29:26 14~-hydroxy-5 [3-cholest-7-en-6one activity in 29:26 3 [3-hydroxy-5 [3-cholest-7-en-6one activity in 29:26 3[3-hydroxy-5[3-cholest-8,14- dien6-one activity in 29:26 ( 14cx-H)3 ~-hydroxy-cholest-4,7dien-6-one activity in 29:27 14c~-hydroxycholest-4,7-dien- 3,6dione activity in 29:27 20-hydroxyecdysone 25-acetate [viticosterone E] activity in 29:26 20-hydroxyecdysone 3-0cinnamate activity in 29:26 22-ep i- 20-hydro xy-e c dys one activity in 29:27 20-hydroxyecdysone activity in 29:26 5 [3-hydroxypterosterone activity in 29:26 (25R/S)-inokosterone activity in 29:26 makisterone A activity in 29:26 3 [3-methoxy- 14cx-hydroxy-5 [3cholest-7-en-6-one activity in 29:26 24R-methyl-2 [3,14ot-dihydroxy5[3- cholest-7,22-dien-6-one activity in 29:27 3 (z-methyl-3 [3,14(z-dihydroxy-5 [3cholest-7-en-6-one activity in 29:26 5 [3-methyl-3 [3,14c~-dihyroxycholest-7-en-6-one activity in 29:27
2c~,3(x, 14c~,20R,22R-pentahydroxy- 5 [3-chole st-7-en- 6-one activity in 29:26 2 [3,3[3,20R,22R,25-p entahydro x y5 [3-cholest-8,14-dien-6-one activity in 29:26 polypodine B activity in 29:26 ponasterone A activity in 29:26 poststerone activity in 29:27 2,3-seco-ecdysone activity in 29:27 24-nor-3~, 14(x,25-trihydroxy-5 [3cholest-7en-6-one activity in 29:27 3 [3,5(z,14c~-trihydroxy-cholest- 7en-6-one activity in 29:27 Callyspongin A 28:712 as starfish fertilisation inhibitor 28:712 Callyspongin B 28:712 as starfish fertilisation inhibitor 28:712 Calmodulin 25:706 inhibitor of 25:706 Calmodulin antagonist activity 25:758 Calmodulin domain-containing protein kinase (CDPK) 25:544 Calmodulin inhibitory activity 2:282, 284 Calmodulin-dependentphosphodiesterase (CAM-PDE) 25:509 Calmodulin-pathways 26:250 Calpurnea aurea 28:400 killing effects on ticks 28:400 Calyceramide A 28:713 as neuraminidase inhibitors 28:713 Calyceramide B 28:713 as neuraminidase inhibitors 28:713 Calyceramide C 28:713 as neuraminidase inhibitors 28:713 CaM antagonists 25:489,492 CaM dependent kinases 25:543,544 CaM inhibitors 25:491 CaM-dependent isoform of PDE (CAM-PDE) 25:490
1062
CaM-dependent PKs I-IV 25:524 CaM-dependent protein kinases 25:493, 527 cAMP 30:192 in regulation of ionotropic receptors 30:192 cAMP formation 30:383 G-protein inhibition 383 cAMP-dependent channels 25:495 cAMP-dependent protein kinase (PKA) 25:488,489,522,547,548 cAMP-dependent protein phosphorylation 25:494 cAMP-gated Na + channels 25:517,523, 524,546 cAMP-induced CaZ+-influx 25:491 cAMP-induced influx 25:497 of K + 25:497 cAMP-phosphodiesterase 25:539 cAMP-response element binding (CREB) 25:523,548 cAMP-sensitive ion channels 25:490, 496,497 Camptothecin 13:654 as anticancer agent 13:654 Cancer 17:137;24:404,40530:55,56, 58,224,732 epidemiology of 24:404-405 Ganoderman lucidum in treatment 30:58 prevention of 30:56 role of free radicals 30:224 role of natural products in 30:55 treatment of 30:56 use of Laminariajaponica Aresch. in 30:56 Cancer cell lines 30:588 cytotoxicity against 30:588 Cancer cell lines inhibition 27:916-918 by biflavonoids 27:916-918 by chalcones 27:913-916 by flavanones 27:908-912 by flavones 27:897,898,899-903 by flavonols 27:903-908 by isoflavones 27:912-913 by 1,2-diphhenylpropane derivatives 27:920-921 by 1,3-diphenylpropane derivatives 27:919-920
Cancer chemoprevention 30:588,591 Hernandia species for 588 Cancer chemoprevention/anti-inflammatory bioassay 29:75 for anti-inflammatory activities 29:76 for anti-mutagenic activity 29:75 for apoptosis induction 29:79 for cancer chemopreventive activity 29:76 for COX-2 iNOS inhibition 29:79 for GSH induction 29:78 for GST formation 29:78 for inhibition of active oxygen species formation 29:78 for inhibition of tumor promotion 29:77 for NF-~cB inhibition 29:80 for ODC inhibition 29:79 for PKC inhibition 29:80 for TNF-~ inhibition 29:80 replication initiation in 29:75 Cancer chemopreventive activity 26:507,508,510,511 ;30:591 in rat mammary carcinogenesis model 30:592 in two-stage mouse skin 30:591 Cancer chemopreventive agent 30:591, 593 from Hernandia species 30:593 in vitro 30:593 activity in mouse mammary organ culture assay 30:593 activity in mouse skin carcinogenesis test 30:593 Cancer chemopreventive agents 24:1061-1062;25:43 Cancer chemotherapy 4:544;24:403464;28:559;30:56,64,841 by substituted benzo [c]phenanthridines 4:544 cisplatin (CDDP) for 28:559 cisplatin in 30:56 doxorubicin 30:56 farnesyl-protein transferase for 24:403-464 side effects of 30:56
1063
Cancer chemotherapy drug 28:559 as doxorubicin 28:559 Cancer growth inhibition 23:290,292 by bruceanol D 23:290,292 ofbruceanol E 23:290,292 ofbruceanol F 23:290 Cancer prevention 30:762 due to green algae 30:762 Cancer related activity 21:634 Cancer target 30:591 chemopreventive drugs as 30:591 Cancerostatic activity 26:452 Cancer-preventing activity 21:641 Candida albicans 28:686;30:739 antibacterial activity against 30:739 antifungal activity against 30:739 Batzella sponge against 28:685 Candidiasis 2:332,425,432;6:261 polyene macrolides in 6:261 Cannabinoid affinity 30:196 for CB2 receptor 30:196 Cannabinoid antagonist 30:198 development of 30:198 Cannabinoid receptor 19:186;30:194 in central nervous system 30:194 in peripheral nervous system 30:194 Cannabinoids 30:193,194,195 anti-nociceptive 194 as analgesic 30:195 anti-nociceptive effects of 30:193 from Cannabis sativa 30:195 role in neuronal excitability 30:194 structure-activity relationships (SAR) of 30:195 Cannabis' sativa 19:186;30.'194,198 as an intoxicant 19:186 as analgesic 30:194 as natural therapeutic herb 30:194 therapeutic use of 30:198 Cannobinoid receptors 25:533 Canscora decussata 22:515 for epilepsy 22:515
Canthium bibracteatum for 22:515 Canthium gueinzii 22:515
for epilepsy 22:515 Canventol 29:111 activity in skin-5 bioassay system 29:111, activity in RAS bioassay system 29:111 activity in TNF~ bioassay system 29:111 Capsaicin 28:436,43730:195,201,202, 206 as complex I inhibitor 28:436, 437 activity of 30:202 antinociceptive action of 30:206 as natural analgesic product 30:195 as vanilloid receptor agonist 30:202 effect on TRPVI expression 30:206 inhibition of NO production by 30:201 Capsaicin analogue 30:193,201 structure-activity requirements of 30:201 Capsaicin induced edema 25:46 inhibition of 25:46 Capsaicin receptor 30:201 lipophilic part of 30:201 Capsazepine 30:201,202 as vanilloid receptor antagonist 30:201,202 effect on iNOS protein synthesis 30:201 nitric oxide inhibition by 30:201 Capsicum species 28:436,400 killing effects of ticks 28:400 Capsimycin 28:138 antifungal activity of 28:138 Carbamazepine 22:507 Carbaoxirose/carbaoxetoses 29:490 against hepatitis B virus 29:493 against herpes viruses 29:491 against HIV 29:491 as glucosidase inhibitor 29:497 in cytomegalovirus infections 29:492
1064
Carbapenem as asparenomycins 4:434 as carpetimycins 4:434 as KA-antibiotics 4:434 as nor-thienamycin 4:434 as OA-antibiotics 4:434 as pharmacophore 4:434 as pluradomycins 4:434 Carbapenem antibiotics 13:495-507 Carbasugars (alias pseudosugars) 29:449 biological effects of 29:449 Carbocyclic nucleoside antibiotic activity of 8:148 antitumor activity of 8:148 antiviral activity of 8:148 Carbocyclic oxetanocin A,G 10:620,621 antiviral activity of 10:620,621 Carbohydrate transporting proteins 7:29 (-)-Carbovir 10:608,609 antiviral activity of 10:608,609 1-Carboxyl group 27:354 for abscisic acid bioactivity 27:354 Carcinoembryonic antigen (CEA) 29:552 as tumor antigen 29:552 in colorectal cancer 29:552 Carcinogen 26:1002-1004 HA as 26:1002-1004 Carcinogen MNU 25:66 Carcinogenesis 20:512,513;26:965; 30:524,591,592,762 DMBA 30:762 in experimental animals 30:591 in mammalian cells 30:592 inhibition of 30:591 initiation of 30:592 natural inhibitors of 30:591 progression phases of 30:592 promotion of 30:592 Carcinogenesis research 15:439 Carcinogenic activity 13:532 of fumonisins 13:532 Carcinogenic study 27:306 of stevioside 27:306
Carcinogenicity 7:8,9;26:677;27:302 ofbenzo [1] pyrene 7:8,9 of madder root 26:677 Carcinogens 21:97;24:1061,1062 Carcinoid cells 27:797 Carcinoma cells 27:844 Carcinoma Ehrlich cells 25:836 Carcinomycin 1:498 Carcurine 25:528 as immunosuppressive drug 25:528 Cardamine pratensis L 22:515 for epilepsy 22:515 Cardanol monoene 30:152 skin irritancy due to 30:152 Cardanols 21:592;30:150-152 biological properties of 30:150-152 Cardenolides 30:691 cytotoxic activity of 30:691 against KB cell line 30:691 Cardiac activity 21:98,669 Cardiac depressant 5:750 Cardiac diseases 30:224 role of free radicals in 30:224 Cardiac glycosides 9:293 Cardiac toxicity 21:158 Cardiotonic 23:499;24:898 aconitine as 24:898 Bacopa monnieri as 499 Cardiotonic activities 21:501 Cardiotonic constituent 17:33 Cardiotonic peptides 5:403 Cardiotonicity 24:875 as biological action 24:875 Cardiovascular activity 21:668 Cardiovascular disease 23:739;30:155, 524 Ginkgoaceae against 155 incidence of 30:524 Cardiovascular effects 26:232 Cardiovascular hypertrophy 26:236 Cardiovascular modulating effects 26:507-509 Cardiovascular system 26:183 effect of Schisandra on 26:183 Cardyceptin (3'-deoxyadexosin) 24:547 antiviral microbial-derived compound 24:547
1065
Caries 27:316 Carinogenesis 9:583 Carminative agent 23:642 of Teucrium sp. 23:642 Carnosic acid 29:188 activity against HIV-1 protease 29:190 antioxidant activities of 29:188 biological activity of 29:188 Carnosol 29:99 activity in DNA assay system 29:99 activity in roam-2 assay system 29:99 activity in skin-1 assay system 29:99 activity in NFkB assay system 29:99 activity in iNOS assay system 29:99 activity in NO assay system 29:99 activity in GST assay system 29:99 activity in CYP assay system 29:99 Carnosol (abietane diterpene) 29:574 effects on HIV- 1 protease 29:574 13-Carotene 30:516,520,524,537,539544,546,548 clinical use of 30:524 in treatment of erythropoietic protoporphyria 30:524 Carotenoids 24:533-540;30:516-518, 520,521-523,525,526,537,541 antioxidant action of 30:516 antioxidant properties of 30:525 as antiviral compound 24:533540 Carp (Cyprinus carpio L.) 28:564;30:64 antitumor activity of 28:564 as diuretic 28:564;30:64 as tonic 30:64 for eye fatigue 28:564 use in eye fatigue 30:64 Carp extract 27:439 antitumor effect of 27:439
Carp oil 28:566;30:55,56,64,65,68,69 anti-tumor activity of 28:560 antimetastatic activity of 30:56, 64,66 antitumor activity of 30:64 components of 30:65 DHA from 30:65 effect on liver metastasis 30:55 effect on matrigel-induced angiogenesis 30:68 effect on tumor growth 30:55 use in tumor prevention 30:64 Carrageenan foot edema test 30:744 Carrageenan induced edema 25:46,220 inhibition of 25:46 Carrageenan induced paw edema 30:744 Carrageenans 30:399,402 mode of action of 30:402 ?-Carrageenans 30:406 inhibitory effect of 30:406 •-Carrageenans 30:406 inhibitory effect of 30:406 Carrot phytocystatin EIP 18 29:592 effects on chymopapain 29:592 effects on chymotrypsin, papain 29:592 effects on papain 29:592 Caruifolins (germacranolide sesquiterpene) 29:574 effects on HIV- 1 protease 29:574 Carvacrol 28:406,426 acaricidal properties of 28:406 as bioactive monoterpenoid 28:426 Carveol 29:83 activity in RAS assay system 29:83 activity in mam-2 assay system 29:83 Carvomenthenol 28:426 as bioactive monoterpenoid 28:426 Carvone 28:426;29:83 activity in AM assay system 29:83 activity in GST assay system
1066
29:83 activity in RAS assay system 29:83 as bioactive monoterpenoid 28:426 Caryophyllene oxide 29:91 activity in CRG assay system 29:91 Casein/CFA 30:775 CVE-treated mice 30:776 immunization with 30:775 Caspase activity 28:320 of TNF-c~ 28:320 Caspase inhibitor 25:2-VAD 25:462 Cassia occidentalis L. for 22:516 Cassia sophera L. for 22:516 Catunaregam nilotica as 22:516 Khaya ivorensis A. as 22:524 Khaya senegalensis as 22:524 Newbouldia leavis as 22:527 Phyllanthus urinaria L. as 22:529 Phyllostachys heterocycla as 22:529 Psidium guyava L. as 22:530 Spilanthes mauritiana as 22:532 Thuja orientalis L. as 22:534 Uncaria rhyncophylla as 22:534 Vernonia chinensis as 22:535 Vemonia hildebrandtii as 22:535 Vitex negundo as 22:535 Ximenia americana L. as 22:535 Cassigarol A 28:575 effects on tumor growth 28:575 (+)-Castanosperime 12:332 inhibitory activity of 12:332 insect antifeedant activity of 12:332 plant growth regulating activity of 12:332 Castanospermine 11:267;27:253 activity against human immunodeficiency virus 27:257 as anti-aids agent 11:267 as anti-hyperglycemic agent 27:257 as an anti-inflammatory agent 27:257
biological activities of 27:255, 256 glycosidase inhibition by 27:256 c~-glucosidase inhibition by 7:12 [3-glucosidases inhibition by 7:12 Castanospermine inhibitor 27:525 of ot,[3,-glucosidases 27:525 Catabolism 25:332,348 of haemoglobin 25:332,348 Catabolite repression 25:313 Catalytic domain 30:830 of plasminogen activator (u-PA) 30:830 Catechin (catechinic acid, catechuic acid) 29:581 effects on collagenase 29:581 (+)-Catechin (flavan-3-ol) 29:572 effects on HIV- 1 protease 29:572 Catechin (flavan-3-ol) 29:579 effects on ACE 29:579 Catechin 3-gallate (flavan-3-ol) 29:584 effects on proteasome CHYlike activity 29:584 Catecholamine-induced vasoconstriction 30:55,56,72,76 Angelica keiskei use in 30:72 effect ofchalcones 30:56 in rat aortic rings 30:56 inhibition by Angelica keiskei 30:55 Catecholamines 25:516;26:1019 dopamine 25:520 epinephrine 25:520 norepinephrine 25:520 Catechol-containing inhibitors 30:226 Caterpillar data 24:866 bioassay of 24:866 CB~ cannabinoid receptor 30:196,198 affinity for 30:196 3-alkyl-5-arylimidazolidinediones as 30:198 CB2 receptor 25:532,533;30:196 cannabinoid affinity for 30:196 CC-1065 3:310,302 antitumor activity of 3:310,302
1067 DNA sequence selectivity 3:304 toxicology 3:302 CC57BC-1 24:956,957 bioactive compounds from 24:956,957 CCK hormone 18:834 CCK-A antagonist 18:863 CCK-B antagonist 18:863 CC14-induced cytotoxicity 25:468 CC14-induced liver injury 25:466,469 CC14-induced liver injury model 25:471 CD20 antigen 25:272 CD25 positive cells 25:454 CD4 positive cells 25:454 CD4 receptor 30:398 interaction of 30:398 CD4 T-lymphocytes 30:396 CD4-antigens 25:454 CD4-positive helper T cells 25:450 CD69 positive cells 25:454 CD71 positive cells 25:454 CD8 positive cytotoxic T lymphocytes 25:454 Cd-induced liver injury model 25:471 CDK2 activity 21:638 CD18 antigens 25:454 cDNA clone encoding tomatinase 25:308 cDNA coding 25:61 cDNA copy of the HIV type-1 (H1V-1) genome 25:941 CDPK 25:542,546 inhibitors of 25:544 Cebocephaly 23:570 Cecropia juvenile hormone synthesis of 3:271 Cedrela tubiflora Bertoni 30:401 antiviral activity of 30:401 Cedrene 28:406 acaricidal property of 28:406 Cedrus odollam 22:516 for epilepsy 22:516 Cefotaxime 26:333 Cefriaxon 25:258 Ceftazidine 25:258 Celaphanol A 29:91 activity in NFkB assay system 29:91
activity in NO assay system 29:91 Celastraceae family 30:636,642,695 antifeedant activity of 30:695 insecticidal activity of 30:695 Celastrolides 30:642,693 against multidrug-resistant strain 30:694 against drug-sensitive strain N 30:694 from celastraceae family 30:642 Celastrus angulatus 23:666 of spinach phenols 23:765 of tomato peel phenolics 23:766 Celastrus gaumeri 30:691 in treatment of diarrhea 30:691 in treatment of snake bite 30:691 Celastrus hindsii 30:690 Celecoxib 30:192 as COX-2 inhibitor 30:192 Celenamide 25:757 Celenamide E 25:778 Cell adhesion 24:1085 inhibitors of 24:1085 Cell aggregation factors 24:1062 Cell apoptosis 26:925-926 role of nitric oxide in 26:925-926
Cell differenciation 26:926 role of nitric oxide in 26:926 Cell division protein kinases (CDKs) 25:526 Cell growth inhibitory agent 30:5 (+)-discodermolide as 30:5 Cell membrane stabilisation 30:523 due to Cs0-carotenoids 30:523 Cell proliferation 30:5,367,495 assessment of 30:495 in vivo inhibition of 30:5 inhibition by 16-desmethyl 30:5 inhibition by a-thioanomers 30:5 inhibition by [~-thioanomers 30:5 inhibitor of 30:5 role of serotonin (5-HT) 30:367 Cell-cell communication 30:523 Cell-free assays 29:40 abutasterone activity in 29:42 ajugalactone activity in 29:42 ajugasterone C activity in 29:42
1068
as gel-shift assays 29:40 as radioligand displacement assays 29:40 cyasterone activity in 29:42 5-deoxykaladasterone activity in 29:42 ecdysone activity in 29:42 22-epi-ecdysone activity in 29:42 24- fluro- 20- hydroxye cdys one activity in 29:42 20-hydroxyecdysone activity in 29:42 inokosterone activity in 29:42 makisterone A activity in 29:42 muristerone A activity in 29:42 polypodine B activity in 29:42 ponasterone A activity in 29:42 poststerone activity in 29:42 turkesterone activity in 29:42 Cell-mediated immunity 30:766,768, 773 against Listeria 30:768 macrophage activation in 30:773 role of cytotoxic T lymphocyte (CTL) 773 Cellular activity 23:168,180 of secosterols 23:168,180 Cellular toxicity 27:876 ofokadaic acid 27:876 Cellulasic 24:983-998 enzymatic activity 24:995-998 tx-Cembra-2,7,11-triene-4,6-diol 29:100 activity in EBV assay system 29:100 activity in PKC assay system 29:100 activity in skin-1 assay system 29:100 activity in ODC assay system 29:100 ~-Cembra-2,7,11-triene-4,6-diol 29:100 activity in EBV assay system 29:100 activity in skin-1 assay system 29:100 activity in ODC assay system 29:100
Cembranoids 8:15 anticancer activity of 8:15 Cembranolide 24:439 as FPTase inhibitor 24:439 as rHFPtase inhibitor 24:440 structures of 24:439 Centipeda orbicularis 22:516 for epilepsy 22:516 Centraherin 29:89 activity in NFkB assay system 29:89 Central analgesic activity 30:200 in anilidopiperidines 30:200 Central nervous system 21:581;28:315; 30:194,370,384,799 cannabinoid receptors in 30:194 depressent activity on 21:581 effect of Crocus sativus 28:315 on central nervous system 21:581 opioid system in 30:799 parts of 30:370 TPH activity in 30:370 Central opioid receptors 30:816 intrinsic activity of 30:816 Cephalosporin C 22:247 Cephalotaxus alkaloids 24:294 cytotoxicity of 24:294 Ceramide 1-sulfates 28:621 as DNA topoisomerase I inhibitor 28:621 Ceratocystis 25:129 Cerbinal 16:302-304 antifungal activity of 16:302-304 Cerebellar dysfunciton 26:1130 as syndrome type-lA 26:1130 Cerebellar granule cells 25:268 role in apoptosis 25:268 Cerebellar granulosa cells 25:269 apoptosis in 25:269 Cerebellar white matter 30:375 hyperplasia of 30:375 Cerebral cortex 30:193,370,377 serotonergic innervations in 30:377 Cerebral grey matter 30:375 hyperplasia of 30:375 Cerebral thrombus 30:839 fibrinolytic agent in 30:839
1069 Cerebrum rudimentary 23:566 Cemilton 27:212 in treatment of benign prostatic hyperplasia 27:212 Cervical carcinoma 25:268;30:405 cGMP-gated ion channel 25:541 cGMP-gated Na+channels 25:517,521 cGMP-radioimmunoassay 26:938 CGP-41251 12:388 cyclic AMP-dependent protein kinase inbitor 12:388 $6 kinase inhibitor of 12:388 tyrosine specific protein kinase inhibitor of 12:388 Chagas disease 2:293,302;24:818,819; 26:673,787;30:740 by Trypanosoma cruzi 30:740 treatment of 26:787 Chalcones 7:427;26:800 antiparasitic activity with 26:800 molluscicidal activity of 7:427 Chamigrenal 26:244 as PAF-induced inhibitor 26:244 [3-Chamydosporol 13:543 toxicity of 13:543 Chelerythrine 27:158,163,164,172,863 biological activities of 27:178, 179 Chelilutine 27:156-158,161,162,158, 163,172 biological activities of 27:178,179 Chemical carcinogenesis studies 30:592 in epidermal cell culture 30:592 of BALB/c mice 30:592 Chemical defence compounds 21:108 Chemical synapses 21:8,9 Chemical transformation methods 30:591 in vivo 30:591 role in chemopreventive activity 30:591 Chemical-induced edema 12:398 Chemical-induced neoplasia 30:311 solid tumor (sarcoma-180) as 30:311 Ehrlich ascites model as 30:311 juglone against 30:311 plumbagin against 30:311
Chemoconvulsants 22:508 Chemo-differentiation therapy 30:498 of acute monocytic leukemia 30:498 Chemokines 25:535 Chemopreventive activity 30:591,597, 766 in mouse mammary organ culture model 30:591 in vitro 30:597 in vitro bioassays for 30:591 of Chlorella vulgaris 30:766 ofisoquinoline alkaloids 30:597 of lignans 30:597 Chemopreventive agent 26:219 genkwanin as 26:219 (+)-lariciresinol as 26:219 sitoindoside II as 26:219 Chemopreventive efficacy 27:386 of limonene carcinogenesis 27:386 Chemoprophylaxis 26:674 Chemosensitizers 30:595 antimalarial drugs as 30:595 Chemotaxonomic markers 26:1128 Chemotherapeutic agent 30:5,330,742 atovaquone 30:330 for colon cancer 30:5 for multi-drug resistant cancers 30:5 for ovarian cancer 5 for taxol-resistant breast cancer 30:5 Chemotherapeutic intervention 30:397 targets for 30:397 Chemotherapy 26:781,782,783 of malaria 26:781,782,783 Chemotherapy drug 27:436 antitumor activity of 27:436 Chest pain 30:203 use of ginseng root in 30:203 Childhood disintegrative disorder (CDD) 30:384,372 Chilo suppressalis dipping assay 29:25 ajugasterone B activity in 29:28 makisterone D activity in 29:28 shidasterone (stachysterone D) activity in 29:28 213,3[3,20R,22R,25-pentahydroxy-
1070
14 [3-methyl-5 [3-cholest-7,12dien-6-one activity in 29:28 Chinese crude drug 28:202 sanggenon A from 28:202 sanggenon C from 28:202 sang-Bai-Pi as 28:202 Chiral monoterpenoids antibacterial activity of 27:381 antifungal activity of 27:381 anti-neoplasmatic activity of 27:386 bioactivity of 27:361,377 Chironomus tentans epithelial cell line 29:32 Chitin 30:95 alkaline hydrolysis of 30:95 Chitinasic 24:999-1001 enzymatic activity 24:999-1001 Chitin-chitosan 30:95-100 effect on blood pressure 30:95 effect on body weight in mice 30:98 effect on fat excretion 30:97 effect on free fatty acid 30:100 effect on hepatic triacylglycerol 30:100 effect on liver weight 30:100 effect on lipase activity 30:96 effect on pancreatic lipase activity 30:95,96 effect on parametrial adipose tissue weight 30:99 effect on serum triacylglycerol 30:100 effect on total cholesterol 30:100 in mice 30:99,100 in vitro 30:95 inhibitory effects of 30:96 intestinal absorption of 30:95 Chitosan 27:402-404;28:560,563 anti-obesity action of 27:402,403 anti-tumor activity of 28:560 biological activity of 27:404 effects on doxorubicin-induced gastrointestinal toxicity 28:563 preventive effects of 28:563 Chitosan inhibitory effects 28:561 on gastrointestinal toxicity 28:561
on immunocompetent organ toxicity 28:561 on myelotoxicity of 5-FU 28:561 c~-Chlamydosporol 13:543 toxicity of 13:543 Chloramphenicol 29:310 against bacillary dysentery 29:311 bacteriostatic effects of 29:311 biological activity of 29:310 effects on Aerobacter ganera 29:311 effects on Bacillus ganera 29:311 effects on Diplococcus ganera 29:311 effects on pneumonia viruses 29:311 effects on Proteus ganera 29:311 effects on rickettsiae 29:311 effects on Staphylococcus ganera 29:311 effects on Streptococcus ganera 29:311 effects on trachoma viruses 29:311 effects on veneral lymphogranuloma viruses 29:311 effects on Vibrio ganera 29:311 effects on viruses 29:311 Chlorella 30:762,764,766,787 detoxicating enzyme activity of 30:766 hypotensive components in 30:787 uses of 30:762 Chlorella diet 30:763 effects of 30:763 on fecal excretion 30:763 Chlorella effect 30:787 on plasma rennin activity 30:787 Chlorella protothecoides 30:766 role in detoxication 30:766 Chlorella vulgaris 25:430,431,450, 452,453,455;30:761,762,766,782 against microbial infection 30:782 antitumor activity of 25:452
1071 effect on gluthathione Stransferase 30:765 effect on skin papillomas 30:762 effects on fecal excretion 30:762 host defensive study of 30:761 immune-active acidic glycoprotein from 25:455 immunological effect of 30:782 mechanism of 30:782 pharmacological study of 30:761 role in dioxin excretion 30:762 role on inhibition of cytochrome P-450 30:766 role on inhibition of malondialdehyde levels 30:766 topical application of 30:762 use in colorectal carcinomas 30:762 Chlorella vulgaris strain CK 22 (CVs) 25:429-433,436,437,440,447,450 antitumor immuno-activity of 25:432 anti-peptide ulcer effect of 25:430 host-mediated activity of 25:431 immunopotentiating effects 25:429 3-Chlorodehydroleucodin 29:90 activity in NFkB assay system 29:90 Chlorogenic acid 25:663,655,657,667, 919-921,930,932-935,937-940, 942-947 antioxidative properties of 25:919,930,935 (+)-Chlorogenic acid 27:421 biological activity of 27:421 Chlorophyllin 30:765 with dioxins 30:765 Chloroquine 26:1030,1035,1037,1038, 1063,1065 Chloroquine potentiating antiplasmodial activity 30:597 in vivo 30:597 of laudanosine 30:597 Chloroquine sensitivity 30:595 in resistant Plasmodium species 30:595
Chloroquine-enhancing activity 26:1065 Chloroquine-enhancing effectiveness 30:596 of alkaloids 30:596 Chloroquine-resistant parasites 25:352 Cholecystokinin 24:910-913 as putative satiety factor 24:910 effect on contraction 24:910-913 effect on relaxation 24:910-913 Cholecystokinin effect 27:799,800 Cholelithiasis 27:378 Cholelithiasis therapy 27:378,382 Choleretic 22:346;24:799 Achyrocline satureioides as 22:346 biological activity 24:799 Choleretic activity 23:35626:399,400, 414 of isofraxidine 23:356 Cholesterol biosynthesis 23:480 inhibition of 23:480 Cholesterol oxides 24:351-398 biological activities of 24:353-376 effect on activity of HMGR 24:373-376 role in coronary heart disease 24:376-381 Cholesterol synthesis inhibition 25:525 Cholesterol variation number (CVN) 24:351,368,369 Cholinergic activity 21:736 Cholinergic antagonists 21:102,109 Cholinergic decumbenines 21:733 Cholinergic receptor 21:51 ;22:16 Cholinergic transmission 22:15 Cholinesterase inhibitor 21:748,749 Cholinestrase inhibitor huperzine A Cholistane-3fl,5a,6p-triols 24:352 cytotoxicity effect of 24:352 Chondroitin sulfate 30:101-103,105, 107,108,109,397 effect on 2-monooleoylglycerol uptake 30:103 effect on adipose cells diameter 30:109 effect on body weight 30:107 effect on fatty acid uptake
1072
30:101 effect on glucose uptake 30:101 effect on hepatic triacylglycerol 30:109 effect on liver 30:108 effect on palmitic acid absorption 30:103 effect on pancreatic lipase activity 30:101,102 effect on parametrial adipose tissue 30:108 effect on rat plasma triacylglycerol levels 30:105 in HIV therapy 30:397 in mice 30:107,108 in vitro 30:101,103 inhibitory action of 30:101 Choriocarcinoma 14:805 vinblastine for 14:805 vincristine for 14:805 Chromogenic assay 30:834 of chromogenic substrate 30:834 specificity of 30:834 Chromone alkaloids 21:123-153 biological activity of 21:123 Chromones 24:499-503 as antiviral compound 24:499-503 Chromophoric oligopeptides 30:835 role in assay 30:835 Chromophoric procedure 30:834,835 role in assay 30:835 Chromosome 30:379 Chromosome exchange 27:304 Chromosome mutation test 27:303 epi-8-Chromozonarol 5:437 antimicrobial activity of 5:437 Chronic diabetes complication 30:697 cataracts in 30:697 peripheral neuropathy in 30:697 retinopathy in 30:697 Chronic experiment 27:313 Chronic inflammation alleviation 24:887-895 by medicinal plants 24:888-895 by neolignan 24:888-890 Chronic leukemia 26:925 Chronic pain model 30:203 activity of ginseng in 30:203
Chronic painful inflammatory diseases 30:206 pro-inflammatory substances in 30:206 Chronic rheumatoid arthritis 30:204 monodesmodides in 30:204 treatment of 30:204 use ofhederaginin 30:204 Chronic toxicity studies 27:308 Chronic viral hepatitis 25:463 Chrysin (5,7-dihydroxyflavone) 29:572 effects on HIV- 1 protease 29:572 Chrysin (5,7-dihydroxyflavone) 29:577 effects on aminopeptidase N 29:577 Chrysosplenol-D 7:413 antimicrobial activity of 7:413 Cichoriin 12:145 inhibitor of dehydropeptidase (DHP- 1) 12:145 Cidofovir 24:486,487 as anti-viral agent 24:486,487 Cimetidine 25:612 Cimicifugic acid A (phenylpropanoid ester) 29:582 effects on collagenase 29:582 Cinchona succiruba 26:779 antimalarial activity of 26:779 1,8-Cineole (eucalyptol) 29:83 activity in TNF assay system 29:83 Cinnamomum camphora 22:516 for epilepsy 22:516 Cinnamophilin 26:240 as PAF-induced inhibitor 26:240 Cinnamoyl ester of crassin 8:15 antileukemic activity of 8:15 Circadian activity 30:369 abnormalities of 30:369 effect on anorexia 30:369 effect on bipolar disorder 30:369 effect on bulimia 30:369 effect on obsessive compulsive disorder 30:369 effect on panic disorder 30:369 effect on schizophrenia 30:369 effect on seasonal affective
1073 disorder 30:369 effect on unipolar depression 30:369 Cirrhosis 30:406 Cirsimaritin 30:726,727,748 antispasmodic activity of 30:748 Cisplatin 26:213;28:559;30:56 cancer chemotherapy drug 30:56 for cancer chemotherapy 28:559 side effects of 30:56 Cissua integrifolia 22:517 for epilepsy 22:517 Citral 29:83 activity in skin-1 assay system 29:83 activity in TPA assay system 29:83 Citronellol 28:426 as bioactive monoterpenoid 28:426 Citrus maxima 22:517 for epilepsy 22:517 Clarithromycin 25:617 Classical cannabinoids 30:195,198 structure-activity relationships of 30:198 Clathsterol 28:702 against HIV- 1 reverse transcriptase (RT) 28:702 Clavaric acid 24:440 inhibition rHFPTase 24:440 Clerodane cajucarinolide 29:100 activity in TLO assay system 29:100 Clerodane diterpenes 30:748 principles of spasmolytic drugs 30:748 Clinical chemoprevention trials 30:592 Clinical development 30:5 for colon cancer 30:5 for multi-drug resistant cancers 30:5 for ovarian cancer 30:5 for taxol-resistant breast cancer 30:5 Clinical studies 30:842 of thrombolytic agents 30:842
Clinical trials 21:750,754 ofBtg A 21:754 ofHup A 21:748-750 Clinical usage 21:138 of flavopiridol 21:138 Clonal expansion 26:921 of antigen-specific T 26:921 Clonidine 25:530 Clonogenic assays 21:259 Clotting disease 30:839 fibrinolytic agent in 30:839 CMV infection 30:405 chemotherapy of 30:405 CNS-activity 21:4 CNS-depressant activity 21:582 Coagulation 26:240-245 role of platelet activating factor (PAF) 26:240-245 Cocaine 26:820 as psychodelic drug 26:820 Cocarcinogen 1:547 Coccidiomycosis 2:422 Cocculus sermentosus 22:517 for epilepsy 22:517 Cochlodinium polykrikoides 30:400,408 anti-influenza activity of 30:408 Coclaurine 24:887 effect as neuromuscular blocker 24:887 Cognitive functions 30:368 role ofraphe nuclei in 30:368 Colchicines 29:357 as antimitotic agents 29:357 as tubulin assembly inhibitor 29:357 in gout treatment 29:357 Colchicum autumnale 25:473 hepatoprotective effect of 25:472 serum ALT activity of 25:473 Colchicum luteum 22:517 for epilepsy 22:517 Colebrookea oppositifolia 22:517 for epilepsy 22:517 Collagen 30:594 platelet aggregation induced by 30:594 Coley's toxin 28:519 anti-tumor activity of 28:519 Colon 26 carcinoma 19:609
1074 Colon cancer 23:293;30:5 clinical development for 30:5 chemotherapeutic agent for 30:5 Colon-38 tumor cells 25:761 Colorectal carcinomas 30:762 in rat model 30:762 induction by 1,2-dimethylhydrazine (DMH) 762 use of Chlorella vulgaris for 30:762 Colorimetric assays 21:508,511,523, 551 Combined effects 28:562 of 5-FU 28:562 of chitosan 28:562 Combined effects 27:438 of 5-fluorouracil 27:438 Combretastatin A-4 24:406 antimitotic inhibitory activity of 24:406 as tubulin transferase 24:408,409 (+)-Compactin 11:335,336 biological activity of 11:335, 336 Competitive inhibitors 7:40,56,69,70 Complex I inhibitor 28:436,437 annonaceous acetogenins as 28:437 capsaicin as 28:436,437 deguelin as 28:436 monotetrahydro furanic derivatives 28:437 piericidin A as 28:436 rotenolone as 28:436 rotenone as 28:436 tephrosin as 28:436 Compositae plants 30:732 as anti-inflammatory effect of 30:732 as antimicrobial agents 30:732 as antitumoral agents 30:732 as antiviral agents 30:732 biological activity of 30:732 medicinal value 30:732 pharmacological activity of 30:732 Comutagenic effect 5:477 of estrogens 5:477 Con A hepatotoxicity 25:464
Con A induced liver injury 25:464,465 Con A model 25:463 Concanavalin A 30:4 mitogenesis induction by 30:4 Conculsive affections 22:511 Allium sativum L. for 22:511 Condensed tannins 29:572 effects on HIV- 1 protease 29:572 Confertdiolide 29:90 activity in TPA assay system 29:90 activity in CRG assay system 29:90 activity in EPP assay system 29:90 Congenital cytomegalovirus 30:374 autistic features in 30:374 Congorinine E-1 29:91 activity in TNF~ assay system 29:91 Conjure maculatum L. 22:517 for epilepsy 22:517 c~-Conotoxin 21:52 ~t-Conotoxins 21:73 Constipation 30:194 as opioid's side effect 30:194 Contact dermatitis 30:168-169 phenolic lipids role in 30:168169 Contotoxins 21:79 Contraction 24:910-913 effect of cholecystokinin 24:910-913 Convulsions 22:510-536,471,559,580, 582,633,742 Aconitumjaponicum Thunb. for 22:510 Acorus calamus L. in 22:510 Aeolanthus suaveolens in 22:511 Aglaia odorata Lour. in 22:511 A llopylus africanus Beouv. for 22:511 Aloe vera L. for 22:511 Arisaema amurense Maxim for 22:512,513 Arisaema consanguineum for 22:512
1075
Artocarpus helerophyllus for 22:513
Caesalpinia bonduc L. for 22:514
Caesalpinia pulcherrima L. for 22:514,471
Canthium bibracteatum for 22:515
Casimiroa edulis for 22:515 Cassia occidentalis for 22:580, 582
Catunaregam nilotica for 22:516 Celtis cinnamomea for 22:516 Curcuma aromatica for 22:518 Deinbollia borbonica for 22:519 Desmodium polycarpum DC. for 22:519
Desmodium triflorum DC. for 22:519
Euphorbia hirta L. for 22:520 Ferulafoetida for 22:521 Ficus capensis for 22:521 Gentiana crassicaulis for 22:521 Gentiana dahurica for 22:521 Gentiana decumbens L. for 22:521
Gentiana dehurica for 22:521 Gentianafetisowii Regel for 22:521
Gentiana macrophylla for 22:521
Gentiana tibetica King for 22:521
Gentiana wutaiensis for 22:522 Gynandropsis pentaphylla for 22:522
Hedeoma pulegioides L. for 22:522
Hoslundia opposita for 22:523 Hoya austrulis R. for 22:523 Jatropha curcas L. for 22:524 Jatropha curcas R. for 22:524 Ledebouriella seseloides for 22:524
Leucas lavandulifolia for 22:525 Lobelia inflata L. for 22:525 Mellittia usaramensis for 22:526 Micromelum compressum for 22:526
Myrica salicifolia for 22:527 Nicotiana tobacum L. for 22:527 Paeonia emodi for 22:527,528 Paeonia officinalis L. for 22:528 Paeonia suffruticosa for 22:528 Palisota ambigua for 22:528 Panax quinquefolius L. for 22:528
Phylanthus emblicata L. for 22:529
Polygonum japonicum for 22:530,633
Pothos scandens L. for 22:530 Psychotria curviflora for 22:530 Randia esculenta for 22:530 Ruta chalespensis for 22:531 Ruta graveolens L. for 22:531 Scopaliajaponica for 22:531, 742
Securidoca longepedunculata for 22:532
Solanum carolinense L. for 22:532
Tetrameles nudiflora for 22:533 use of arnica in 22:559 use of Artocarpus heterophyllus in 22:513 use of Basilicum polystachyon in 22:514 Veratrum nigrum L. for 22:534 Xylotheca tettensis var. fissistyla for 22:535 Zanthoxylum holtzianum for 22:535 Zingiber ottensi for 22:536 Convulsions in children 22:514-516, 524,527,529,530,532,534,535,580, 582 Caesalpinia pulcherrima L. for 22:514 Canthium bibracteatum for 22:515 Casimiroa edulis for 22:515 Cassia occidentalis for 22:580, 582 Catunaregam nilotica for 22:516 Khaya ivorensis A. for 22:524 Khaya senegalensis A. for 22:524
1076
Newbouldia leavis for 22:527 Phyllanthus urinaria L. for 22:529 Phyllostachys nigra Lodd for 22:529 Psidium guyava L. for 22:530 Spilanthes mauritiana for 22:532 Uncaria rhyncophylla as 22:534 Vernonia chinensis for 22:535 Vernonia hildehrandtii for 22:535 Vitex negundo for 22:535 Ximenia americana L. for 22:535 Convulsions in infants 22:519 Desmodium pulchellum for 22:519 Convulsive affections 22:517,527 Coleus aromaticus for 22:517 Nardostachys jatamansi DC. for 22:527 Convulsive cough 22:517 Citrus maxima for 22:517 Convulsive disorders of children 22:534 Thuja orientalis L. for 22:534 Coprotoxins 18:698 Coridin display activity 22:202 Corilagin (hydrolysable tannin) 29:572 effects on HIV- 1 protease 29:572 Corn earworm 24:865 bioassay of 24:865 Corn Hageman Factor Inhibitor (CHFI) 29:602 effects on c~-amylase 29:601 effects on a-amylase inhibitor 29:602 effects on cereal (x amylase/ trypsin inhibitor family homologue 29:601 effects on cereal or-amylase 29:602 effects on Factor XIIa 29:602 effects on CM homologues 29:601 effects on trypsin inhibitor homologue 29:602
inhibitor proteins 29:601 RA5 as 29:601 RBI (Ragi bifunctional I) as 29:601 rice allergenic protein as 29:601 SIc~4 as 29:601 Coronaridine 25:533 as immunosuppressive drug 25:533 Coronary artery ligation-reperfusion 25:594 Coronary heart disease 24:376-381, 30:55,72 Angelica keiskei use in 30:72 role of cholesterol oxides 24:351-398 role of natural products in 30:55 Cortical abnormalities 30:378 Corticomimetic activity 21:657 (+)-Corytuberine 30:563,589 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:589 Coscinoderma mathewsi 28:672 as protein phosphatase inhibitor 28:672 3-Costoyloxydehydroleucodin 29:90 activity in NFkB assay system 29:90 Costunolide 24:848;29:89 activity in AM assay system 29:89 activity in Colon-1 assay system 29:89 activity in iNOS assay system 29:89 activity in NFkB assay system 29:89 activity in ODC assay system 29:89 activity in RAS assay system 29:89 carcinoma 24:848 topoisomerase inhibitory activity 24:848 Cotton pellet granuloma 25:46 inhibition of 25:46
1077 Cotyledon bioassay 26:583 Coughing spasm 22:525
Leucas lavandulifolia for 22:525 cis-Coumaric acid 29:101 activity in CRG bioassay system 29:101 Coumarins 24:499-503;25:472 as antiviral compound 24:499-503 hepatoprotective mechanism of 25:472 fS-O-cis-p-coumaroyl alphitolic acid 28:623 anti-microbial activity of 28:62 f3-O-trans-p-coumaroyl alphitolic acid 28:623 anti-microbial activity of 28:62 fS-O-cis-p-coumaroyl maslinic acid 28:623 anti-microbial activity of 28:62 f3-O-trans-p-coumaroyl maslinic acid 28:623 anti-microbial activity of 28:62 Cowdria ruminantium 28:394 as rickettsial pathogens 28:394 COX enzymes 29:672 expression of 29:672 in hormonal production 29:672 in platelet aggregation 29:672 in prostacyclin production 29:672 in wound healing 29:672 inhibitors of 29:673 mechanism of action of 29:673 role in Alzheimer's disease (AD) 29:673 role in kidney function 29:672 role in pregnancy 29:672 role in stomach 29:672 COX inhibitor 29:673 ;30:192 allergic attacks-promotion by 29:674 aspirin as 30:192 aspirin-induced asthma (AIA) syndrome by 29:675 assay for 29:677 asthmatic attacks-promotion by 29:674
baicalin as 29:680 cell line based assay for 29:677 enzyme immunoassay (EIA) for 29:677 for familial adenomatous polyposis 29:674 ibuprofen as 30:192 in AD pathogenesis 29:673 in bladder tumor 29:673 in breast tumor 29:673 in cancer treatment 29:673 in cerebrovascular diseases 29:674 in osteoarthritis 29:673 in rheumatoid arthritis 29:673 in skin treatment 29:673 indomethacin as 30:192 naproxen as 29:673 radioimmunoassay for 29:677 rofeCOXib as 29:673 role in broken bone growth 29:674 role in congestive heart failure 29:674 role in exacerbate coronary disease 29:674 role in immune system 29:674 role in renal failure 29:674 role in ulcer healing 29:674 scintillation proximity assay for 29:677 to alleviate symptoms 29:673 to treat pain 29:673 to treat swelling 29:673 toxicity of 29:674 up-regulation of 29:673 wogonin as 29:680 COX/LOX dual inhibitors 29:671,675 as anti-inflammatory agents 29:671 assays for 29:676 cardio-protective functions of 29:676 fromAcacia catechu 29:678 from Scutellaria baicalensis Georgi. (Lamiaceae) 29:678 from Scutellaria lateriflora L. 29:678 natural type of 29:671
1078 nonsteroidal anti-inflammatory drugs (NSAIDs) as 29:672 prostaglandins suppression by 29:676 role in angiotensin II-induced contractions 29:675 role in coronary vasoconstriction 29:675 role in lens protein-induced occular inflammation 29:675 therapeutical benefits of 29:675 COX/LOX natural dual inhibitors 29:681 3-(4 '-ac etoxy-3 ',5 '-dimethyl) benzylidene- 1,2-dihydropyrrolo [2,1-[3]quinazoline-9-one as 29:693 acetylenes as 29:682 aethiopinone as 29:688,691 alcohols as 29:681 aliphatic sulfides as 29:684 alkaloids as 29:692 alkamides as 29:683 artonin E 29:702 artonon E as 29:706 atractylochromene as 29:695 aucubin as 29:686 bornyl ferulate as 29:696 D-boswelic acid 29:692 buddledin A as 29:687 6-(3-carboxybut-2-enyl)-7hydroxy-coumarin as 29:699 catechins as 29:708 centaureidin as 29:704 chalcones as 29:707 chlorogenic acid as 29:697 cis-hexadec- 11-en-7,9-diynote acid as 29:683 coumarins as 29:699,700 crysins as 29:702 curcumin as 29:695 daphnetin as 29:699 6-demethyl-vignafuran as 29:709 (2,3- dihydro- 1H-p yrro liz in- 5-yl) acetic acid as 29:693 5,3 '- dihydroxy-4 '-me thoxy-7carbomethoxyflavonol as 29:704 11,12-dihydroxy-6-oxo-8,11,13-
abietatriene as 29:688 11 (S),I 6(R)-dihydroxy-octadeca9Z, 17-diene- 12,14-diyn- 1-yl acetate as 29:682 diterpenes as 29:687
dodeca-2E,4E,8Z, 10E/Ztetraenoic acid isobutylamide as 29:684 E-isolinaridial as 29:690 E-isolinaridial methylketoine as 29:690 epigalloactechin-3-gallate (EGCG) as 29:708 falcarindiol as 29:682 fatty acids as 29:681 fisetin as 29:704 flavones as 29:702 flavonoids as 29:700 flavonols as 29:704 from Aaronsohnia 29:683 from Achillea 29:683 from Allium sativum L. 29:684 fromAllium ursinum 29:684 from Anacyclus 29:683 from Angelica pubescens F. Biserrata (Apiaceae) 29:699 from Artocarpus communis 29:706 from Asteraceae 29:703 from Atractylodes lancea 29:694 fromAtuna racemosa 29:708 from Bidens campyltheca Schultz 29:682 from Boswellia serrata Roxb. (Burseraceae) 29:691 from Buddleja globosa Hope (Buddlejaceae) 29:686 from Callna vulgaris 29:691 from Ceiba pentandra 29:708 from Celastrus orbiculatus 29:708 from Chymacyparis taiwanesis 29:698 from Curcuma longa 29:695 from Echinacea angustiJblia 29:684 fromEchinacea species 29:683 from Euniceafusca 29:690 from Helichrysum picardii
1079 29:702 from Ircinia spinosula 29:694 from Linaria saxatilis var. glutinosa 29:689 from Macfadyena unguis-cati 29:696 from Morus mongolica 29:705 from Nigella satvia L. (ranunculaceae) 29:694 from Notopterygium incisum T. 29:696 from Peucedanum ostruthium (L.) 29:699 from Phillyrea latifolia L. 29:685 from Piper sarmentosum Roxb. 29:684 from Pseudopterogorgia elizabethae 29:689 from Psoralea corylifolia L. 29:705 from Punica granatum, L. Punicaceae 29:701 from Salvia aethiopis L. (Labiatae) 29:690 from Salvia athiopis (Labiatae) 29:687 from Saposhnikovia divaricata 29:682 from Scrophularia scorodonia L. 29:685 from Sideritis angustifolia 29:687 from Sideritis mugronensis 29:701 from Sophora flavescense 29:705 from Syzygium carynocarpum 29:708 from Syzygium malaccense 29:708 from Tanacetum microphyllum 29:703 from Tanacetum parthenium (L.) 29:686,703 from Tanacetum vulgare 29:703 from Teucrium species 29:687 from Urtica dioica L. (Urticaceae) 29:697
from Vantanea peruviana 29:708 from Zanthoxylum chalybeum Engl. 29:692 fuscoside B as 29:691 gnaphalin as 29:704 gossypetin as 29:704 gossypin as 29:704 gossypol as 29:697 harpagosides as 29:686 6-hydroxy-2-(2hydroxy-4methoxyphenyl)benzo furan as 29:709 3-hydroxy-flavone as 29:704 hypolaetin as 29:702 hypolaetin-8-glucoside as 29:702 iridoids as 29:685 kaempferol as 29:704 kenusanone C as 29:705 kurarinone as 29:705 kuwanon C as 29:702 lagascatriol as 29:688 linoleic acid as 29:682 medicarpin as 29:709 6-methoxy luteolin as 29:702 6-methoxy luteolin-3'-methyl ether as 29:702 6-methoxy-kaempferol-3,4'dimethyl ether as 29:704 methyl 1-propenyl disulfide 5oxide as 29:685 O-methyl-pseudopterosine as 29:689 5-methyl-sophoraflavanone B as 29:705 morin as 29:704 morusin as 29:702 myricetin as 29:704 naphthol as 29:698 naringenin as 29:705 naringin as 29:705 oleic acid as 29:682 palmitic acid as 29:682 parthenolide as 29:687 pentadeca-6,8,10-triynoic acid as 29:683 phenethyl ferulate as 29:696 phenolic compounds as 29:695 1-propenyl 1-(1-propenyl
1080 sulfinyl) propyl disulfide as 29:685 psoralidin as 29:706 quercetagetin 29:3,6,3'-trimethyl ether as 29:704 quercetin as 29:704 6-(2-quinolinymethoxy)etodolac as 29:693 quinones as 29:694 rutin as 29:704 safynol-2- O-isobutyrate as 29:683 sangenon D as 29:706 sanggenon B as 29:706 sesquiterpenes as 29:686 sophoraflavanone D as 29:705 sophoraflavonone G as 29:705 tanaparthin-(x-peroxide as 29:687 teucrin A as 29:688 thymoquinone as 29:695 triterpenoids as 29:691 tropolone as 29:698 ursolic acid as 29:692 COX- 1 enzyme 30:192 in kidney 30:192 in stomach 30:192 physiological effects of 30:192 role in nflammation 30:192 COX-2 enzyme 30:192 inflammation induction by 30:192 COX-2 gene expression 30:319 in RAW2647 macrophages 30:319 COX-2 inhibitors 30:192 celecoxib as 30:192 in treatment of inflammatory disorders 30:192 in treatment of pain disorders 30:192 rofecoxib as 30:192 COX3 enzyme 30:192 in brain 30:192 Coxsackievirus 30:412 Aloe barbadensis against 30:412 CP-263114 24:434,435 weak inhibitor of 24:435
CPH82 26:170 for treatment of rheumatoid arthritis 26:170 CPT activity 21:458 Crassin acetate 8:15 antibiotic activity 8:15 Crassin 8:15,19 antitumor activity 8:15,19 Creatine kinase (CK) 30:837,844 hydrolysis by F-II 30:837 Crenomytilus grayanus 30:408 anti-influenza activity of 30:408 Cribraria intricata 29:256 fruit bodies of 29:256 Cribraria purpurea 29:258 antimicrobial activity of 29:258 Cribricellina cribraria sp. 28:619 antimicrobial activity of 28:619 Crimean-Congo haemorrhagic fever virus (CCHFV) 30:412 Crocin effects 28:316,319 on LTP-blocking effects of ethanol 28:316 on TNF-o~-induced cell 28:319 Crocus sativus 28:315 effect on central nervous system 28:315 Cromolyn 22:170 Crossopetalum ,umeri 30:660,662 cytotoxic cardenolide from 30:660,662 Croton oil induced edema (CRO) 25:45 Croton oil induced edema inhibition 25:46 Croton oil-induced ear edema 25:556 Croton oil-induced inflammator edema 25:55 inhibitory effects on 25:55 Crown gall tumors 9:386 Cryosurgery 30:405 Cryptocin 28:123 against phytopathogenic fungi 28:123 Cryptoporic acids 29:87 activity in AOS assay system 29:87 activity in TLO assay system 29:87
1081
activity in PLA assay system 29:87 Cryptosporidiosis 26:788 treatment of 26:788 CSF (colony stimulating factor) 25:455, 960,963 Chymotrypsin (CT) 13:536 synergistic effects 13:536 toxicity 13:536 Cuanzin 8:283,284,289,293 antiarrhytmic activity of 8:283 antihypertensive activity of 8:283 Cubitermes sp. 8:220 defence secretion of 8:220 Cucumaria echinata 28:720 neuritogenic activity of 28:720 Cucumis colocynthis L. 22:518 for epilepsy 22:519 Cucumis sp. L. 22:518 for epilepsy 22:518 Cudraphenone B 28:230 biological activity of 28:230 Cudraphenone D 28:230 biological activity of 28:230 Cumambrin A 29:90 activity in NFkB assay system 29:90 Cuminaldehyde 29:83 activity in AM bioassay system 29:83 Cuminum cyminum 28:427 acaricidal activity of 28:427 Cuminyl alcohol 29:83 activity in AM assay system 29:83 Curcuma comosa 26:884 anti-inflammatory activity of 26:884 Curcumenol 29:90 activity in HPT assay system 29:90 Curcumia longa L. 25:469 hepatoprotective activity of 25:469 serum transaminase activity of 25:469 Curcumin 24:215-264 anti-tumor promoter 24:215-264
Cutaneous leishmaniasis 30:742 treatments for 30:742 use of medicinal plants 30:742 CVE 30:768,769,770,773,775,776 against Listeria 30:768 against listerial infection 30:768 as therapeutic agent 30:773 as prophylactic 30:773 effect on expression of mRNA 30:770 effect on growth of Listeria monocytogenes 30.769 in antigen-specific response 30:773 in mice 30:773 on IFN? mRNA expression 30:775 on IL- 12 mRNA expression 30:775 therapeutic potential of 30:768 to control allergy 30:776 CVE-treated MAIDS 30:769,770 Listeria antigen in 30:770 DTH response in 30:770 CVS 25:443,445,447,450 antimetastatic effect on 25:441 CVS induced antitumor immunity 25:454 antitumor effect 25:440 resortive effect on progenitor cells 25:448,449 and tumor specificity 25:442 Cyanobacterial hepatotoxins 9:496-499 Cyanobacterial inhibitory compounds 26:357-364 Cyanobacterial toxicity 26:376 testing of 26:376 Cyanobactericides 26:382 Cyanocycline A 10:103 antitumor activity of 10:103 Cyclase activity 30:639 of Maytenus aquifolium 30:639 ofSalacia campestris 30:639 Cycleahomine (bisbenzylisoquinoline) 29:578 effects on ACE 29:578 Cyclic adenosine monophosphate (cAMP) phosphodiesterase 24:855
1082
Forsythia suspensa inhibition of 24:855 Cyclic AMP phosphodiesterase 25:539 3',5'-Cyclic AMP-dependent protein kinase (PKA) 25:512 Cyclic AMP-dependent protein phosphorylation 25:483 3'-5'-Cyclic AMP-sensitive cation channels 25:483 Cyclic dependent kinase 25:4,798,799 Cyclic GMP-phosphodiesterases 25:541 Cyclic nucleotide phosphodiesterase 25:512 Cyclic polypeptide inhibitors 27:879 (-)-Cyclizidine 12:305,306 biological activity 12:305,306 Cycloartenol (cycloart-24-en-3 [3-ol) 29:586 effects on CHY 29:586 Cycloartobiloxanthone 28:230 biological activity of 28:230 c~-Cyclocitral 28:406 acaricidal properties of 28:406 13-Cyclocitral 28:406 acaricidal properties of 28:406 Cycloheximide-induced amnesia 25:958 Cyclohexylidene 24:883-887 potentiating effects on neuromuscular blocking action 24:883-887 Cyclolinteinone 29:111 activity in COX bioassay system 29:111 activity in iNOS bioassay system 29:111 activity in NFkB bioassay system 29:111 Cyclooxygenase inhibitor 25:593; 28:16,17 Cyclooxygenase inhibitor 28:16,17 broussoaurone A as 28:16,17 Cyclooxygenase inhibitor 28:17 broussoflavonol F as 28:17 Cyclooxygenase inhibitor 30:594 aspirin as 30:594 Cyclooxygenase inhibitory activity 26:46,556 ofjenisseensosides A-D 26:46
Cyclooxygenase-2 (COX-2) genes 26:927 Cyclophosphamide 25:431 Cyclophosphamide treatment 25:447 Cyclopiazonic acid 28:119 as calcium uptake inhibitor 28:119 D-Cycloserine 26:366 Cyclosporin 22:58,247,257 Cyclosporin A 26:486 Cyclotheonamide A-E 26:1179,1180 Cycloxygenase 25:47 inhibition of 25:47 Cylindramide 28:139 cytotoxic activity of 28:139 Cylindrols 24:445-447 bovine brain FPTase activity of 24:446 m-Cymene 28:406 acaricidal property of 28:406 Cynaropicrin 29:90 activity in NO assay system 29:90 activity in TNFa assay system 29:90 Cynodon dactylon L. Pets. 22:518 for epilepsy 22:518 Cyperus esculentus L 22:518 for epilepsy 22:518 Cyperus rotundus L. 22:401,518 for epilepsy 22:518 Cysteine 30:836 a2-macroglobulin inhibition by 30:836 Cysteine protease inhibitor 29:592 effects on cysteine protease 29:592 from Arabidopsis thaliana Cysteine proteases 29:569 aleurain as 29:569 bromelain as 29:569 Ca2§ 29:569 calpains as 29:569 caricain as 29:569 cathepsin B as 29:569 chymopapain as 29:569 ficin as 29:569 from Plasmodiumfalciparum 29:569
1083 in Alzheimer's disease 29:569 in gastric cancer 29:569 in type 2 diabetes 29:569 inhibition by 29:569 papain-like 29:569 protease actinidin as 29:569 type I pyroglutamyl peptidases as 29:569 Cysteine proteinase inhibtor 25:370 Cytochalasins 24:549 antiviral microbial-derived compound 24:549 Cytochrome oxidase-inhibiting cyanide 25:513 Cytochrome P-450 inhibitor 4:621 Cytochrome P-450 monooxygenase 25:318,597 Cytochrome P-450-dependent monooxygenase 25:413 Cytochrome P450-dependent 30:765 monooxygenases 30:765 inhibition by chlorophyll 30:765 Cytokine gene 25:470 Cytokine mRNA 30:771,775 expression in 30:771,775 RT-PCR analysis of 30:771,775 Cytokine production 26:921 ;30:689 inhibitory effect on 30:689 Cytokine receptors 27:825 Cytokine tumour necrosis factor ~x (TNF-cz) 26:916 Cytokine/cell growth factor 30:768 GM-CSF as 30:768 Cytokines 25:463;27:82;30:192,770 as pain mediator 30:192 HODEs induced genesis of 27:82 in mammalians 27:82 neutrophils as 30:192 Cytokinesis-block micronucleus assay 21:642 Cytokinins 4:227-229,7:89,90,94, 20:531 ;25:367,379;26:581,583,584 Cytolylic/Cytostatic factors 23:132 Cytolytic activity 30:95 of mouse lymphocytes 30:95 Cytolytic cytostatic factors 23:132 Cytolytic lymphocytes (CTL) 25:273 Cytolytic T cells 25:453
Cytolytic T lymphocytes 25:271 Cytomegalo virus infections 25:431 Cytomegalovirus 30:394,404,412 biological properties of 30:404 pathogenetic properties of 30:404 Cytopathic activity 20:442;21:665,744 Cytopathic components 30:397 Cytopathic effect 24:483;30:397 of HIV-1 30:397 of HIV-2 30:397 Cytopathogenicity 15:76 Cytoplasmic guanylate cyclase 25:382 Cytoplasmic inhibitor protein 26:926 Cytoplasmic proteins 28:321 in apoptosis 28:321 Cytoprotective activities 21:655 Cytoprotective activity 26:224 Cytosolic Ca ++ 30:383 elevation by G-protein 30:383 Cytosolic calcium mobilization 30:339 inhibition of 30:339 Cytosolic dehydrogenase activity 25:423 Cytosolic PIA2 25:717 Cytosolic sphingosine kinase 25:264 Cytostatic activity 18:775-778;20:796; 21:637;28:146 of eliamid 28:146 Cytostatic effect 26:924 Cytostatic T cells 25:453 Cytotoxic 12:390;24:799,845 against human neurablastoma NB-1 cells 12:390 biological activity 24:799,845 staurosporine 12:390 Cytotoxic action of 25:477 of TMB (3,4,5,-trimethoxybenzoy) 25:477 Cytotoxic activity 4:101;5:84,342-346, 353 ;21:399,404,634,637,655,675; 23:78,96,172,177,180,186,234,235, 285,296,299,301,308,313,346,649, 660,679,698,797,800,801; 24:309-318,837;26:216-218,452,470, 485 ;27:927;28:17,65,217,220,227, 468,470;30:156,589,590,624,691, 692 against KB cell line 30:692
1084
against leukemia cells 23:74,186 demethylsonodione 30:589 of (-)-deoxypodophyllotoxin 30:589 of (-)-hemone 30:590 of (-)-nymphone 30:590 of (-)-yatein 30:590 of (+)-corytuberine 30:589 of (+)-epiaschantin 30:590 of (+)-epimagnolin 30:590 of (+)-epiyangambin 30:590 of (+)-hernovine 30:589 of (+)-laurotetanine 30:589 of (+)-magnoflorine 30:589 of (+)-malekulatine 30:590 of (+)-N- formyldehydroovigerine 30:589 of (+)-N- formylnornantenine 30:589 of (+)-N-formylovigerine 30:589 of (+)-N-hydroxyhemangerine 30:589 of (+)-N-methylhemangerine 30:590 of (+)-ovigerine 30:590 of (+)-ovihernangerine 30:590 of (+)-vateamine-2' [3-N-oxide 30:590 of 15-methoxycarbonyl nagilactone D 28:468 of 15ot-hydroxy-pristimerin 30:692 of 16-hydroxy podolide 28:468 of 1-deoxy-2ot-hydroxyagilactone A 28:468 of 2a-hydroxynagilactone F 28:470 of 3,5-diiodetyramine 23:235 of 3,5-diiodotyramine 23:235 of 3-deoxy-2ot-hydroxynagilactone E 28:470 of 7- formyldehydrohernangerine 30:589 of 7-formyldehydronomantenine 30:589 of 7-formyldehydroovigerine 30:589
of 7-hydroxy-6-methoxy- 1methylisoquinoline 30:589 of 7-oxohernagine 30:590 of 9-methoxycamptothecine 5:84 of Acalycgorgia 5:368,369 of alga 5:342,346 of anacardic acids 30:156 of ansamycin 23:96 of Antiaris toxicaria (Moraceae) 28:220 ofantiarone I 28:227 ofantiarone J 28:220 ofantiarone K 28:220 ofantiarone L 28:220 ofartocarpus flavonoids 28:220 ofartonin A 28:220 ofartonin B 28:220 of artonin E 28:217,227,220 ofartonin H 28:220 ofaulacocarpin A 23:797 ofaulacocarpin B 23:797 of aulacocarpinolide 23:797 ofbetulinic acid 28:17,40 ofbicyclic phloeodictine B 28:688 of bipinnatins 23:177 ofbroussoflavonol B 28:227 ofbroussoflavonol C 28:227 of camptotheeine 5:84 of celastroloids 23:649 ofcembranes 23:180 of cembrones 23:180 of chaparrin 23:299 of coclenterate 5:342 ofcucurbitacin B 28:65 ofcurcumenes 23:180 of cyclic peptides 4:101,102 of cycloheterophyllin 28:220 of defensins 23:346 of dehydrobruceantin 23:285, 308,313 of dehydrobruceantinol 23:308,313 of doxorubicin 23:299 of eurycomalactone 23:301 of flavonoids 27:927 of galanal A 23:801 ofgalanal B 23:801 ofgancaonin R 28:227
1085
ofglucarubolone 23:299 ofglyasperin A 28:227 of glycyrol 28:227 of guaianolides 23:180 of guianolides 23:180 of hernandonine 30:589 of hernanymphine 30:589 of heterophyllin 28:220 of holacanthone 23:299,301 of indaquassin-X 23:296,299 of inumakilactone A 28:468 of inumakilactone B 28:468 of kallilolides 23:180 ofkazinol B 28:227 of Licania genus 28:65 ofLicania heteromorpha 28:65 ofLicania michauxii 28:65 oflicochalcone B 28:227 of licoricidin 28:227 of longilactone 23:301 ofMaytenus amazonica 30:691 of mollusk 5:342 of morusin 28:227 ofnagilactone A 28:468 ofnagilactone B 28:468 ofnagilactone C 28:468 ofnagilactone D 28:468 ofnagilactone E 28:468 ofnagilactone F 28:468 ofnagilactone G 28:468 of N-hydroxyovigerine 30:589 of N-methylcorydaldine 30:589 of N-methylovigerine 30:590 of norartocarpetin 28:227 of ochraceolide A-E 23:698 of Penstemon campanulatus 24:837-838 ofpodolactone E 28:470 of pseudopterolides 23:180 of samaderine-Y 23:299 of samaderine-Z 23:296,299 of sampsoniones 30:624 of sesquiterpenes 23:180 of sesquiterpenes alkaloids 23:660,679 of sponge 5:342-346,353 of thalifoline 30:590 of tunicate 5:342 of ulithiacyclamide 4:101
Cytotoxic agent 2:404,293-303,653; 19:601 ;26:760;30:310 D-aminoacyl-anthraquinone derivatives as 30:310 from Nerium oleander 9:293-303 savinin 13:653 Cytotoxic cardenolide 30:660,662 against KB cell line 30:660 from Crossopetalum gaumeri 30:660,662 Cytotoxic effects 23:531 of resveratrol 23:531 Cytotoxic flavonoids 27:925 Cytotoxic guanidine-alkaloids 25:706 Cytotoxic hydrophilic taxol derivatives 12:221 Cytotoxic peptides 4:83,110 Cytotoxic T cells (CTLS) 24:131; 30:778 Cytotoxic T lymphocytes 26:950 Cytotoxic triterpenes 30:690 Cytotoxic value 27:930 of flavonoids 27:930 of vinblastine 27:782 Cytotoxicity 5:388;21:134,136,150, 174,257,259,260,262,263,265,267, 269,270,271,273,274,284,311,364, 410,634,643,656,661,690,704,744; 23:96,97,187,218,238,249,250,253, 255,272,274,277,290,292,299,308, 317,701,274 ;24:294,352,740,867; 26:212-213,1185 ;27:94,924,926; 28:118,121 ;30:27,59,226,560,588, 593,596,690 3-Aminoflavones for 27:926 against cancer cell lines 30:588 against marine lymphoma 23:187 against Meth-A 30:59 against uterine carcinoma 30:596 bioassay of 24:867 in COLO-205 (colon carcinoma) 30:690 in KB nasopharynx carcinoma 30:690 of 26:4'-demethyldeoxypodophyllotoxin 26:213 of (-)-6'-hydroxyyatein 26:212
1086
of (-)-hemone 26:212 of (-)-nymphone 26:212 of (-)-yatein 26:213 of 13-apopicropodophyllin 26:213 of 4- 0-butanoyl-4'-demethyl podo-phyllotoxin 24:740,741 of 5-methoxydehydropodophyllotoxin 26:212 of ailantinol A 23:317 of amarolide 23:299,317 of amphidinolide B 5:396 of benzopentathiepins 23:238 of benzotrithianes 23:238 of bripiodionen 28:117,118 ofbruceanol C 23:288 ofbruceanol D 23:290,292 ofbruceanol E 23:290,292 ofbruceanol F 23:290,292 ofbruceoside-A 23:317 of catechins 27:924 ofcephalotaxus alkaloids 24:294 of chaparrin 23:299 of cholistane-3fl,5 Gt,6p-triols 24:352 ofcystodytin A 23:272 ofcystodytin B 23:272 of cystodytin C 23:272 of cystodytin J 23:272 ofcystodytin J 23:272 of dehydro-13-peltatin methyl ether 26:212 of dehydro-bruceantarin 23:308 of dehydro-bruceantin 23:308 of dehydro-bruceantinol 23:308 of dehydrokuanoniamine B 23:272 of dehydropodophyllotoxin 26:212 of deoxydehydropodophyllotoxin 26:213 of deoxypicropodophyllin 26:213 of dercitamide 23:274 ofdiplamine 23:272 of doxorubicin 23:299 of dysodanthin A 26:212 of dysodanthin B 26:212 of ecteinascidins 23:253,255 of equisetin 28:121
of Etoposide 26:213 of eurycomalactone 23:301 of fatty acid derivatives 23:218 of flavonoids on cancer cell line 27:893 ofGanoderman lucidum 30:59 ofglaucarubolone 23:299 ofglycookadaic acid 5:384,385 ofhalichondrin B 5:378,380 ofhalichondrin C 5:380 of holacanthone 23:299 ofhomohalichondrin A 5:380 ofhomohalichondrin B 5:380 of indaquassin B 23:299 of isodeoxypodophyllotoxin 26:213 ofisoquinoline alkaloids 30:588 of isoquinolines 30:588 ofkuanoniamine A 23:272 of lamellarins 23:242,245,249, 250 oflignan constituents 30:588 of longilactone 23:301 of macbecin I 23:97 of maytenfolone-A 30:690 of mecbocin I 23:97 of megaphone acetate 26:212 ofnaphthomycin A 23:66,96 ofnapthomycin A 23:96 ofnorhalichondrin A 5:378,380, 383,384 ofokadaic acid 5:384,385,389 ofpantherinine 23:272 of penazetidine A 23:194 of quassinoids 23:285-333 of quinones 23:537 of samaderine X 23:288,299 ofshermilamine B 23:272 of shinjulactone C 23:317 oftaurookadaic acidf 5:388 of theonellamides 26:1185 oftumour necrosis factor 5:387 ofvaramine A 23:272 of vatdiospyroidol 23:535 of voramine A 23:272 of yadanzioside 23:317 of yadanzioside 23:317 of[3-alaninookadaic acid 5:388 of ~-amyrin 23:535
1087 of 6-aminovalcrookadaic acid 5:388 of ],-aminobutyrokadaic acid 5:388 role ofheverlines A-C 30:596 to EL4 cells 30:27 Cytotoxicity assay 21:641 ;30:593 against JB6 cells 30:593 Cytotoxin agents 24:1055,1085 Cytotstatic activity 25:433,434 of Meth A tumor cell antigen 25:444 lc~,25(OH)2D analogue 30:497 in human osteosarcoma 30:497 D l-agonists 21:58 Dl-antagonists 21:68 D ~-receptor 21:18 1o~,25(OH)2D2 30:494,495 binding affinity of 30:494 bone resorbing activity of 30:495 calcemic effect of 30:495 D2-agonists 21:58 D2-antagonists 21:68 1ct,25(OH)2D3 30:484,494,495,500 analogues of 30:484 binding affinity of 30:494 bone resorbing activity of 30:495 calcemic activity of 30:484,495 effect on bone maturation 30:484 effect on calcium metabolism 30:regulation 484 effect on immune responsiveness 30:484 effect on malignant cell differentiation 30:484 in multifunctional biological responses 30:484 pharmacokinetics parameters of 30:500 use in cancers 30:484 use in immune disorders 30:484 use in psoriasis 30:484 1,25(OH)2D3 calf thymus receptor 30:496 competitive binding to 30:496 lo~,25(OH)2D3 metabolites 30:495 D3-receptor 21:18
1oc,25(OH)2D4 30:495,499,500,501,504 bone resorbing activity of 30:495 calcemic effect of 30:495 effect on animal model with osteoporosis 30:499 in rat 30:504 metabolic pathway of 30:504 pharmacokinetics parameters of 30:500 lct,25(OH)2D4 activity 30:497 affinity of 30:497 bone mobilization of 30:497 on calcium transport 30:497 lc~,25(OH)2D4 drug 30:503 for immune disorders 30:503 for osteoporosis 30:503 for skin diseases 30:503 Dactylocyclines A 29:315 from Dactylosporangium strain ATCC 53693 29:315 stereochemistry of 29:315 sugar moieties of 29:315 DAGO 30:801,802 inhibitory effects of 30:801 Daleformis (pterocarpinoid phytoalexin) 29:581 effects on ECE 29:581 from Dalea filiciformis (Fabaceae) 29:581 Dalton's lymphoma ascites 26:303 Dammaradienol (dammara-20,24dien-3[3-ol) 29:586 effects on CHY 29:586 Dammarane saponins 24:144,146 Daphne cannabina 27:833 activator from 27:833 Daphne mezereum 27:833 activator from 27:833 Daturafastuosa L. 22:519,742 for epilepsy 22:519,742 Datura metel L. 22:519 for epilepsy 22:519 Daucus carota W. 22:519 for epilepsy 22:519 Daunomycin 26:802 6-Deacetoxy- 14,15-deepoxy-xeniculin 29:103
1088
activity in AOS bioassay system 29:103 Debenzylation 30:441 Decoctions 30:704,691 for medicinal purposes 30:704 Decumbenine B 21:733,734 biological activity of 21:736 Defence gene activation 25:396 Defence mechanism 23:180 against predation 23:180 Defense proteins 25:370 serine proteinase inhibitor I as 25:370 Deguelin 28:436 as complex I inhibitor 28:436, 437 Dehydration 30:486 of phenyl sulfone derivative 30:486 Dehydro-[3-peltatin methyl ether 26:212 cytotoxicity of 26:212 Dehydroabietic acid 29:99 activity in EBV assay system 29:99 Dehydrobruceantarin 23:308 cytotoxicity of 23:308 Dehydrocostus lactone 29:89 activity in AM assay system 29:89 trans-Dehydrocrotonin 29:100 activity in CRG assay system 29:100 1,2,3,4-Dehydrode oxyp o dophyllotoxin 30:592 as EBV inhibitor 30:592 Dehydroglyasperin C 28:228 biological activity of 28:228 Dehydrohernandaline 30:563,594 as platelet aggregation inhibitor 30:594 Dehydroleucodin 29:90 activity in COX assay system 29:90 activity in NFkB assay system 29:90 Dehydropodophyllotoxin 26:212 cytotoxicity of 26:212 1,2,3,4-D ehydropodophyllotoxin 30:568,592
as EBV inhibitor 30:592 Dehydroschisandrol A 26:245 as PAF-induced inhibitor 26:245 Deinbollia borbonica 22:519 for epilepsy 22:519 DEL 30:800,814 antinociceptive effects of 30:800 resistance to enzymatic degradation 30:814 DEL C analogues 30:815 antinociceptive action of 30:815 Delayed-type allergy suppressant activity 25:46 ofserotonin agonists 25:46 Delphinidin (anthocyanidin) 29:582, 584 effects on LELA 29:584 effects on MMP 29:582 Delphinium denudatum Wall 22:519 for epilepsy 22:519 Delta opioid receptor 30:799,800 role in analgesia 30:799 Delta receptors 22:24 Deltorphin B 30:801,804,807,817 activity in RJ bioassay 30:807 agonist activity of 30:817 antinociception activity of 30:804 8-selective opioid agonist 30:817 Deltorphin C 30:813 pharmacological activity of 30:813 Deltorphin II 30:810 activity in fail flick test 30:810 Deltorphins 30:799,801,814 as 8 agonist 30:799 from frog skin 30:801 4'- O-Demethldehdropodophyllotoxin 26:227 antifungal activity of 26:22 Demethylated gardenin A (5,6,7,8,3',4', 5'-nonahydroxyflavone) 29:572 effects on HIV- 1 protease 29:572 4'-Demethyldeoxypodophyllotoxin 26:213 cytotoxicity of 26:213
1089
6,7-Demethylenedeoxypodophyllotoxin 30:568,592 as EBV inhibitor 30:592 Demethylmoracin I 28:18 as aromatase inhibitor 28:17 Demethylsonodione 30:570,589 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:589 Dendrimeric multiple antigenic peptides 25:335 Dendrodoine 5:412 cytotoxic activity of 5:412 Dental surgery 30:192 use of non-steroidal antiinflammatory drugs (NSAIDs) 30:192 use of prostaglandin inhibitors 30:192 Denticulatin A and B 17:24 antimicrobial activity of 17:24 Denudatin 26:240 antifeeding activity of 8:160 as PAF-induced inhibitor 26:240 1'-Deoxy- 1'-fluoro-ABA 27:334 biological activity of 27:334 1-Deoxy-213,3[3-epoxy nagilactone A 28:480 anti-feedant activity of 28:480 6-Deoxy-6-fluoro-sucrose 7:69 as competitive inhibitors 7:69 Deoxydehydropodophyllotoxin 26:213 cytotoxicity of 26:213 14-Deoxylactucin 29:89 activity in CRO assay system 29:89 Deoxymannojirimycin 7:15,41,42 ot-mannosidase inhibition by 7:15,41,42;10:539 [3-mannosidase inhibitor of 10:539 Deoxypicropodophyllin 26:213 cytotoxicity of 26:213 (-)-Deoxypodophyllotoxin 30:568,588, 589,595
activity against A549 (human lung adenocarcinoma) 30:588 activity against HT-29 (human colon carcinoma) 30:588 activity against KB-16 (human oral epidermal carcinoma) 30:588 activity against P-388 (murine lymphocytic leukemia) 30:588 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:589 platelet aggregation inhibitor 30:594 14-Deoxy-taondiol methyl ether 6:55 from (+)-manool 6:55 synthesis of 6:55 Deoxytedanolide 19:558 antitumor activity of 19:558 2-Deoxy-[3-KDO 30:465 inhibitor of CMD-KDO synthetase 30:465 Dephosphorylation of retinoblastoma protein 25:270 Depressant activity 21:581 on central nervous system 21:581 Depression 30:368,627 role of hyperforin inhibitor 30:627 role of serotonin (5-HT) 30:368 Depsipeptide antibiotics 21:408 DER 30:800,814 antinociceptive effects of 30:800 resistance to enzymatic degradation 30:814 Dercitin sp. 28:686 antitumor activity of 28:686 antiviral activity of 28:686 immunomodulatory properties of 28:686 Dermatophilus congolensis 28:394 skin infection of cattle by 28:394 Dermorphin 30:799,801,807,813,814 as ~5agonist 30:814 as g agonist 30:799
1090 as g-selective agonist 30:807 inhibitory effects of 30:801 pharmacological activity of 30:813 Desferrioxamine 26:992 Desipramine 26:1063 Desmethoxy streptonigrin 24:454 FPTase inhibition by 24:454 Desmutagenic activity 21:642 2-Desoxo- 15 a-methyl- 14a-hydroxyMFA 28:347 nematocidal activity of 28:347 2-Desoxoparaherquamide A 28:331 nematocidal activity of 28:331 Detox 28:543 for immunotherapy 28:543 Detoxification 21:4,108,161,165,177; 26:1012 of xenobiotics 26:1012 Detoxification ofheme 25:334,335,343 Detoxification of tomatine 25:313 Dexamethasone 25:463,464 as down-regulator of TNF-a 25:465 as immunosuppressive drug 25:464 1-Dexoynojirimycin 10:543-546,549 antihyperglycemic activity of 10:526 antiviral activity of 10:529 Dextran induced edema 25:46 Dextran sulphate 30:397,398 activity in quantitative syncytium formation assay 30:398 in HIV therapy 30:397 in vivo efficacy of 30:398 inhibitory effect of 30:398 on viral binding 30:398 D-Gal N 25:466 hepatic intoxication with 25:466 D-Gal N/LPS 25:459-461 liver intoxication with 25:462 D-Gal N/LPS model 25:468 D-Gal N/LPS-induced liver injury 25:460,467,472-474 D-gal N/TNF-a 25:460,461 liver intoxication with 25:462 D-GalN/LPS model 25:464
D-GalN/LP S-intoxication 25:468 D-GaiN-induced cytotoxicty 25:468 D-GaiN-induced liver injury 25:463, 469 DHA-Chlorella 30:789,788,790 anti-hyperlipidemic effect of 30:788,790 1a,2a-Diacetoxy-6 ~,9[3-difuroyloxy-4 [3hydroxydihydro- [3-agarofuran 29:87 activity in EBV assay system 29:87 Diagnostic criteria 30:372 for autistic disorder 30:372 3,5'-Diallyl-2'-hydroxy-4-methoxybiphenyl 24:861 anti-fungal activity of 24:861 Dianosides A-1 26:32 analgesic activity of 26:32 Dianthus barbatus 26:32,56 anti-inflammatory agent from 26:32 Dianthus superbus var. longicalycinus 26.'56 anti-bleeding activity of 26:56 anti-tumor activity of 26:56 Diaphoretic agent 23:642 of Teucrium sp. 23:642 Diarrhetic shellfish poisoning (DSP) 28:653 yessotoxin in 28:653 Diarrhetic shellfish poisons 21:301 Diarrhoea 30:394,406,691 Celastrus gaumeri in treatment of 30:691 2,6-Diaryl-3,7-dioxa bicyclo [3.3.0.] octanes 24:740,755-762 Diarylheptanoids 27:852 activity of 17:375;27:852 Diazepam binding inhibitor 27:803 Dibenzyltrisulfide 28:403 as oviposition inhibitor 28:403 Dibromide synthesis 29:482 as fucosidase inhibitors 29:482 Dicoumarol (coumarin) 29:584 effects as anticoagulant 29:584
1091
Didanosine 24:474,486,488 as anti-viral agent 24:474,486, 488 Didemnin B 5:421 antitumor activity of 5:421 antiviral activity of 5:421 immunosuppressive activity of 5:421 Didemnin-B (isodidemnin-I) 10:251-258,262,263,266-272,276, 277,281,285,291 Didemnins 5:421,254-257 antitumor activity of 5:421, 254-257 antiviral activity of 5:421,253, 254 biological properties of 10:241-302 cytotoxic activity of 5:421 immunosuppressive activity of 10:257,258 D i d e m n u m sp. 28:631,634 anti-human immunodeficiency virus (anti-HIV) activity of 28:631 Diemenensin A 17:24 antibacterial activity of 17:24 (-)-8,8a D i - e p i - s w a i n s o n i n e inhibitory activity of 12:331,332 7~, 8cc, 1313,14f3-Diepoxyabietan- 18-oic acid 29:99 activity in EBV assay system 29:99 DIF assay system 29:87 3 ~3-acetoxy-8 ~3-isobutyrylo xyreynosin activity in 29:87 Differentiation 30:496 of human HL-60 leukemia cells 30:496 Digestive organs motility accelerator 24:900 gingerol as 24:900 2,3-Dihdydroaromaticin 29:90 activity in NFkB assay system 29:90 24,24-Dihomo- 1c~,25-dihydroxy vitamin D3 pharmacological activity of 11:385,386
(-)-Dihydrocarveol 29:83 activity in AM assay system 29:83 Dihydrodidemnin 27:804 biological activity of 27:804 Dihydrodiisoeugenol 26:226 antibacterial activity of 26:226 meso Dihydroguaiaretic acid 26:240as PAF-induced inhibitor 26:240 11 o~,13-Dihydrohelenalin methacrylate 29:90 activity in NFAT assay system 29:90 activity in NFkB assay system 29:90 activity in CRO assay system 29:90 11 o~,13-Dihydrohelenalin tigulinate 29:90 activity in NFAT assay system 29:90 activity in NFkB assay system 29:90 Dihydrolicoisoflavone A 28:243 anti-Helicobacter p y l o r i activity of 28:243 Dihydroperillic acid 29:83 activity in RAS assay system 29:83 5',6'-Dihydrousambarensine 26:1062 anticancer activity of 26:1060 18,19-Dihydrousambarine 26:1062 anticancer activity of 26:1060 (2S)-2 ',4' Dihydroxy-2"-( 1-hydroxy- 1methylethyl)-dihydro furo[ 2,3h]flavanone 28:17 as aromatase inhibitor 28:17 2c~,19cc-Dihydroxy-3-oxo- 12-ursen-28oic acid (ursane triterpene) 29:574 effects on HIV- 1 protease 29:574 4a, 10cc-Dihydroxy-3-oxo-8[3-isobutyryloxyguaia- 11 (13)-en- 12,6c~-olide 29:90 activity in DIF assay system 29:90 11,12-Dihydroxy-6-oxo-8,11,13abietatriene 29:99
1092
activity in COX assay system 29:99 9,10-Dihydroxy-7-methoxynaphtho [2,3-c] pyran- 1(1H)-one (semivioxanthin) 11:130 antibiotic activity of 11:130 antifungal activity of 11:130 7~, 15-Dihydroxyabieta-8,11,13-trien18-al 29:99 activity in EBV assay system 29:99 from Larix kaempferi 29:99 15,18-Dihydroxyabieta-8,11,13-trien-7one 29:99 activity in EBV assay system 29:99 18-nor-4et, 15-Dihydroxyabieta-8,11,13trien-7-one 29:99 activity in EBV assay system 29:99 15,18-Dihydroxyabieta-8,11,13-trien-7one- 18-acetate 29:99 activity in EBV assay system 29:99 2,5-Dihydroxybenzyl 27:870 for inhibitory activity 27:870 3,2'-Dihydroxyflavone 29:572 effects on HIV- 1 protease 29:572 1,4-Dihydroxy-germacra-5 E-10( 14)diene 29:88 activity in CRO assay system 29:88 2R,5 R-D ihydroxymethyl- 3R,4Rdihydroxypyrrolidine 10:545 almond emulsin f3-glucosidase inhibitor of 10:545 yeast invertase inhibitor of 10:545 yeast c~-glucosidase inhibitor of 10:545 1 ~,25-Dihydroxyvitamin D3 30:484 effect on bone maturation 30:484 effect on calcium metabolism regulation 30:484 effect on immune responsiveness 30:484
effect on malignant cells differentiation 30:484 6ct,7 [3-Dihydroxyvouacapan- 17 [3-oic acid 29:103 activity in AOS bioassay system 29:103 1,4-D imethoxy- 2,4 ',4"- trihydroxy-pterphenyl 29:267 as cytotoxic principle 29:267 3 '-(T,T-dimethylallyl)-kievitone 28:228 biological activity of 28:228 8-(T,T-dimethylallyl)-wighteone 28:228 biological activity of 28:228 7,12-Dimethylbenzanthracene (DMBA) 30:762 effect on skin papillomas 30:762 ( 1'E, 5'E)-2-(2', 6'-Dimethylocta- 1', 5',7'trienyl)-4-furoic acid 29:91 activity in PLA assay system 29:91 ( 1'E, 5'Z)-2-(2', 6'-Dimethylocta- 1', 5', 7'trienyl)-4-furoic acid 29:91 activity in PLA assay system 29:91 2,2'-N,N-Dimethyltetrandinium dichloride (bisbenzylisoquinoline) 29:578 effects on ACE 29:578 Dioncopeltine A 26:822,823 antiplasmodial activity of 26:822,823 Dioncopeltine B 26:822,823 antiplasmodial activity of 26:822,823 Diosmetin (5,7, 3'-trihydroxy-4'methoxyflavone) 29:577 effects on aminopeptidase N 29:577 Diosmin (3',5,7-trihydroxy-4'methoxy-7-O-rutoside) 29:579 effects on ACE 29:579 Dioxin 26:756 antagonist effect of 26:756 9ot,13ct-epi dioxyabiet-8(14)-en- 18-oic acid 29:99 activity in EBV assay system 29:99
1093
Diprenylated chalcones 29:773 antileishmanial activity of 29:774 Diprenylorobol 28:2436,8anti-Helicobacter pylori activity of 28:243 Dipyrone 30:192 as analgesic/antipyretic 30:192 Direct-acting mutagen 30:174 daunorubicin as 30:174 methyl methanesulfonate as 30:174 Discodermelide 30:3,4,5,6,10-12,13-19, 17,19-21,22-26 against human lung carcinoma cell 30:5 as antitumor agent 30:3 as immunosuppressive agent 30:3 as microtubule stabilizing agent 30:5 biological activity of 30:4 inhibition of host-splenomegaly response 30:4 suppression of two-way mixedlymphocyte reaction 30:4 Discodermia 28:138,679 antifungal activity of 28:139 cytotoxic activity of 28:139,679 Diseases 30:70 arteriosclerosis 30:70 asthma 30:70 atopic dermatitis 30:70 hyperlipidemia 30:70 Disodium salt of phosphocombretastatin A-4 24:406 angiogenesis inhibitory activity of 24:406 anti-tumor vascular inhibition of 24:406 Dispsacus saponin C 30:204 antinociceptive effects of 30:204 Distamycins (pyrrole amidines) 24:546 antiviral microbial-derived compound 24:546 c~,~'-Disubstituted 3-piperidinol alkaloids 29:420
analgesic activites of 29:420 anesthetic activities of 29:420 antibiotic activities of 29:420 Diterpenoids 30:707 biological activity of 30:707 Dithiocarbonates 26:1091,1092 antimicrobial activity of 26:1091,1092 Diuretic 23:499 Bacopa monnira as 23:499 Diuretic activity 12:398;28:200 of genus Morus 28:200 Diuretic agent 23:642 of Teucrium sp. 23:642 Diversifolin 29:89 activity in NFkB assay system 29:89 Diversifolin methyl ether 29:89 activity in NFkB assay system 29:89 Di dopamine receptor 25:529 DMACA assay 21:511,522,524,525 DMACA protocols 21:522,523 DMBA/TPA induced skin tumor 25:48 inhibition of 25:48 (Dmti, Tic2)DYN-A-(1-11)-NH2 30:809 activity in functional bioassay 30:809 DNA polymerase 21:96;25:895 DNA polymerase activity 23:218 DNA polymerase B 25:871 DNA polymerase inhibitors 25:868 DNA topoisomerase 21:96 DNA topoisomerase I inhibitors 28:621 ceramide 1-sulfates as 28:621 DNA viruses 30:395 DNA-damaging activity 20:467 DNA-damaging agents 20:460,20:461 DNA-damaging antitumor activity 25:796 DNA-damaging natural products 20:457-500 DNA-methyl green assay 30:733 DNA-scission 30:164 by alkylresorcinol 30:164 DNA-virus 30:394 hepatitis B type of 30:394
1094
Dolabrane akendo 1 29:100 activity in TPA bioassay system 29:100 [3-Dolabrin (tropolone monoterpene) 29:583 effects on carboxypeptidase A collagenase 29:583 Dolastatin 5:421 ;12:10,477,485,486 Dolastatin 10 28:145,649 antiproliferative activity of 28:145 as antineoplastic agent 28:649 Dolastatin 15 28:145 antiproliferative activity of 28:145 Dolastatin 3 4:87-89 synthesis of 4:87-89 Dolastatin 3 28:648 as antineoplastic agent 28:648 Dopa 23:241 Dopamine 25:516,530,535,536,538,662 Dopamine D~ receptors 25:531 Dopamine D2 receptor 25:530,532 type of G-protein-linked receptor 25:530 Dopamine receptor D l 21:101 Dopamine receptor D2 21:101 Dopamine receptors 21:95;22:22; 25:531 Dopamine signalling 25:531 Dopaminergic receptors 21:68 Dorstenia brasiliensis 29:795 anticancer activities of 29:797 antileukodermic activities of 29:797 antimutagenic activities of 29:797 anti-tumor activities of 29:797 artemicide activities of 29:797 bacteriophagicide activities of 29:797 cytotoxic activities of 29:797 hepatoprotective activities of 29:797 radical-scavenging activities of 29:797 uses of 29:798 viricide activities of 29:797
Dounomycin 24:547 antiviral microbial-derived compound 24:547 Down-regulator 25:465 of TNF-a 25:465 Down-regulators (TNF-a) 25:465 PGE2 as 25:463 dexamethasone as 25:463 Doxorubicin 24:547;28:559,560,562; 30:56 antiviral microbial-derived compound 24:547 as cancer chemotherapy drug 28:559;30:56 gastrointestinal toxicity by 28:562 immunotoxicity by 28:562 myelotoxicity by 28:562 Doxorubicin (adriamycin) 4:317-319 Doxorubicin plus chitosan 28:560 tumor growth inhibition by 28:560 Doxorubicin-induced gastrointestinal toxicity 28:563 effects ofchitosan 28:563 preventive effects of 28:563 Doxysilychristin 26:255 3as antihepatotoxic agent 26:255 DPDPE 30:817 analgesic activity of 30:817 Drosophila melanogaster BIl bioassay 29:55 alkaloids activity in 29:56 ampelopsin B (distilbene) activity in 29:55 apiole activity in 29:56 bisphenol A activity in 29:56 camosiflosides activity in 29:55 cis-resveratrol (monostilbene) activity in 29:55 croweacin activity in 29:56 cucurbitacins activity in 29:55 deacetylpicracin activity in 29:55 diethylphthalate activity in 29:56 2,3-dihydro-3 [3-methoxyichromolide activity in 29:55 2,3-dihydro- 3 [3-methoxy-
1095
withacnistine activity in 29:55 2,3-dihydro-3 [3-methoxywithaferin A activity in 29:55 23,24-dihydrocucurbitacin F activity in 29:55 2,6-dimethoxy-3,4-methylenedio xy- 1-(2-propenyl)benzene activity in 29:56 ecdysteroiods activity in 29:55 24-hydroxycarthamosterone activity in 29:55 industrial bioactive compounds from 29:56 isoasarone activity in 29:56 3-epi-isocucurbitacin D activity in 29:55 isomitraphylline activity in 29:56 isopteropodine activity in 29:56 kobophenol B (tetrastilbene) activity in 29:56 limonoids activity in 29:55 lindane activity in 29:56 marginatine activity in 29:56 cis-miyabenols (tristilbene) activity in 29:55 phenylalkanoids activity in 29:56 pipermargine activity in 29:56 prieurianin activity in 29:55 rohitukin activity in 29:55 stilbenoids activity in 29:55 suffruticosols (tristilbene) activity in 29:55 (~-viniferin (tristilbene) activity in 29:55 withanolides activity in 29:55 Drosophila melanogaster imaginal disc cell lines 29:33 Drug-DNA complex 23:9 Drymis winteri 30:206 anti-inflammatory properties of 30:207 antinociceptive properties of 30:206 DTAOH 30:810,811 antagonistic effect of 30:810 6 antagonist activity of 30:811
DTAOH+DEL II 30:810 activity in tail flick test 30:810 DTH response 30:768,769 after infection 30:768 mononuclear cell infiltration due to 30:769 swelling due to 30:769 DTOH 30:810,811 6-antagonist activity of 30:811 antagonistic effect of 30:810 physiochemical properties of 30:811 DTOH+DEL II 30:810 activity in fail flick test 30:810 d-Tyr(Me)2-Phe-G-V-V-NH2 30:813 binding bioactivity of 30:813 functional bioactivity of 30:813 d-Tyr(Me)2-Phe-NH2 30:813 binding bioactivity of 30:813 functional bioactivity of 30:813 Duct cell carcinoma of breast 1:276 Dulucoside A 29:101 activity in TPA bioassay system 29:101 Duocarmycin C1 29:339 against Gram-positive bacteria 29:339 against Staphylococcus aureus 29:339 as anticancer antibiotics 29:339 in lymphocyte leukemia 29:339 in sarcoma 29:339 DYN-A-(1-11)-NH2 30:809 activity in functional bioassay 30:809 (tic2)DYN-A-(1-11)-NH2 30:809 activity in functional bioassay 30:809 (tic2)DYN-A-(1-13-)-NH2 30:809 activity in functional bioassay 30:809 Dynorphins 27:801;30:806,193 as endogenous peptide opioids 30:193 biological activity of 27:801 Dysidin 28:142 antifeedant activity of 28:142 immunosuppressant activity of
1096
28:142 molluscidal activity of 28:142 Dysodanthin A 26:212 cytotoxicity of 26:212 Dysodanthin B 26:212 cytotoxicity of 26:212 Dyspepsia 5:754 DI3E blockers 27:283
Earthwom 30:825,840 as antipyretic 30:825 as antitumor extract of 30:840 as diuretic 30:825 to treat clotting diseases 30:825 use in folk remedy 30:825 Earthworm fibrinolytic enzymes 30:826, 832,836,837,839,840,843 as fibrinolytic agent 30:839 as medicine 30:843 as plasmin-activator 30:839 biological function of 30:840 from Lumbricus rubellus 30:826 gene expression of 30:843 immunological results of 30:840 structure-based inhibitor modeling of 30:832 Earthworm plasminogen activator (e-PA) 30:826,843 Earthworm-tissue plasminogen activator (e-TPA) 30:826,843 EBA-EA activation inhibition assay 25:58 Ebenifoline E-1 29:91 activity in TNFot assay system 29:91 EBV 25:46 EBV assay 25:45;29:88,99 methyl 8Gt,14a, 12ct, 13c~diepoxy-abietan- 18-oate activity in 29:99 EBV assay system 29:87,100 19-nor-Abieta-4(18),8,11,13tetraen-7-one activity in 29:100 abieta-8,11,13-trien-7-one activity in 29:99 abieta-8,11,13-triene-7c~, 15,18triol 7-acetate 29:99
cedrol activity in 29:87 10[3-hydroxycedrol activity in 29:87 12-hydroxycedrol activity in 29:87 EBV bioassay systems 29:100 EBV inhibitor 30:592 1,2,3,4-dehydrodeoxypodophyllotoxin as 30:592 1,2,3,4-dehydropo dophyllotoxin as 30:592 6,7-demethylenedeoxypodophyllotoxin as 30:592 bursehemin as 30:592 epimagnolin as 30:592 Hernandia ovigera as 30:592 podorhizol as 30:592 EBV-EA activation 25:59 induced by TPA 25:59 EBV-EV activation 30:695 effect of Tripterygium wilfordii 30:695 inhibition of 30:695 Ecdysteroid agonists 29:22 8-O-acetylharpagide as 29:24 against diphtera 29:22 against lepidoptera 29:22 as elicitors 29:23 as insecticides 29:22 bisacylhydrazines as 29:22 disadvantages of 29:22 3 ,5-di-tert-4-h ydro x y- Nisobutylbenzamide as 29:24 from Ajuga reptans 29:24 in gene switch systems 29:23 maocrystal as 29:23,24 nonsteroidal 29:22 4-phenylamino- 1,2,3,4tetrahydroquinolines as 29:24 QSAR studies of 29:22 RG-102240 (GS-E) as 29:23 RH-0345 (halofenozide) as 29:23 RH-2485 (methoxyfenozide) as 29:23 RH-5992 (tebufenozide) as 29:23 2[3,3 [3,20R,22R-tetrahydroxy-25-
1097
fluoro- 5 [3-c hole st- 8,14-dien-6one as 29:18,19 Ecdysteroid antagonists 26:555 Ecdysteroid antagonists ampelopsin B 29:54 activity in B~xbioassay 29:52 applications of 29:56 as pest control agents 29:56 biomedical applications of 29:59 bisphenol A as 29:54 classes of 29:52 cucurbitacins as 29:53 cucurbitanes as 29:53 diethylphthalate as 29:54 2,3-dihydro-3 [3-hydroxy withacnistine as 29:54 environmental protection by 29:59 from Hemsleya carnosiflora 29:53 from lberis umbellata 29:53 24-hydroxycarthamosterone as 29:54 lindane as 29:54 pipermargine as 29:54 preurianin as 29:54 cis-resveratrol as 29:54 rohitukin as 29:54 use in crop species 29:57 use in gene switching technology 29:59 cx-viniferin as 29:54 Ecdysteroids 29:3 antiatherosclerotic effects of 29:9 as chemical defence 29:8 as growth stimulator 29:9 as hormonal disruptors 29:8 as tonics 29:9 bioassay systems for 29:24 biological activities of 29:4,9 3-dehydroecdysone as 29:7 25-deoxyecdysone as 29:7 effects in Homosapiens 29:9 effects on bile acid production 29:9 effects on cellular proliferation 29:9
effects on differentiation 29:9 effects on insect growth 29:7 effects on mammalian cells 29:39 effects on physical performance 29:9 effects on vertebrates 29:60 for gene-switching systems 29:21 from Ajuga decumbens 29:60 hormonal roles of 29:6 in embryonic development 29:5 in medicines 29:9 makisterones as 29:7 mode of action of 29:4 molecular modeling studies of 29:44,45 non-steroidal agonists of 29:16 of arthropods 29:4 pharmacophore hypothesis for 29:46 polypodine B as 29:7 ponasterone A as 29:7 poststerone as 29:7 pterosterone as 29:7 receptors of 29:14 role in crop protection 29:17 role in metamorphosis 29:5 role in moulting 29:5 role in reproduction 29:5 rubrosterone as 29:7 taste receptors for 29:17 Echinatin 28:228 biological activity of 28:228 Echinoclasterol sulfate 28:705 as antifungal substance 28:705 as cytotoxic steroid 28:705 from Echinoclathria subhispida 28:705 phenethylammonium salt 28:705 Ecklonialactone A 19:554 cytotoxic activity of 19:554 ECs 24:888-890 by magnosalin 24:888-890 Ecteinascidia turbinata 28:640,641 antitumor activity of 28:640 Edema 22:115;25:46 induced by 25:46
1098
Edema inhibition (HPA) 25:46 by 12-O-hexadecanoyl- 16hydroxy phorbol- 13-acetate (HHPA) 25:45 Edema relief 23:362 by coumarin 23:335,356,357, 353,368,376,393,550,553 Edudiol 28:228 biological activity of 28:228 EFE 30:835,838,840-842 as plasminogen activator inhibitor 30:842 assays of 30:835 by photoreaction 30:841 fibrinolytic medicine from 30:842 in acute cerebral thrombosis 30:842 in acute diseases 30:842 in cerebrovascular thrombus 30:842 in peripheral limbs arteriovenous thrombus 30:842 in prevention of blood clotting 30:842 in radiation therapy 30:841 inhibition by fibrin 30:838 role in dissolution of thrombus 30:842 to treat AMI 30:842 use of antitumor drugs 30:840 EFE-immobilized polyurethane surface 30:841 as antithrombogenic agent 30:841 effect on platelet activation 30:841 effect on platelet adhesion 30:841 Effective insect growth inhibitors 26:858 calopeptin as 26:858 dehydrodiisoeugenol as 26:858 galbacin as 26:858 galbegin as 26:858 licarin as 26:858 licarin B as 26:858 sesamin as 26:858
sesamolin as 26:858 veragensin as 26:858 Effector-receptor complexes 27:379 EGb 28:185 activity against MPTP 28:184 effects on neuroendocrine system 28:185 effects on phospholipid metabolism 28:185 protective activity of 28:184 EGF receptor kinase 25:797,870 EGTA-Ca 2+ buffer system 25:490 EGTA-treated plasma membrane 25:492 Ehrlich ascites carcinoma 25:939,957; 26:303 Ehrlich Ascitis tumor cells 21:664 Ehrlich carcinoma 19:609;23:130 Eicosanoid production 25:615 Eicosanoid signalling 25:374 eIF4E-dependent mRNA translation 25:526 Eisenia fetida 30:826,828,829,832 fibrinolytic activity of 30:826 Elaeocarpus tuberculantus for 22:520 ELAM-1 expression 30:70,71,291 baicalein effect on 30:291 induction by TRAP 30:70,71 Elastase inhibitor 5:590 from Streptomyces noboritoensis KM-2753 5:590 Electrically evoked contractions 30:801 Eleutherobin 30:5 as microtubule stabilizing agent 30:5 Eliamid 28:146 cytostatic activity of 28:146 fungicidal activities of 28:146 nematocidal activity of 28:146 Elicitins receptor 25:396 Elicitor activity 25:397 Elicitors 25:393,394 Elkin-Ahn-Houk model 30:437 for asymmetric induction 30i437 Ellagic acid 25:545,938;29:571,579 as inhibitor of PKA 25:550 as inhibitor of PKC 25:550 effects on ACE 29:579
1099 inhibition of Candida albicans aspartic protease 29:751 inhibition of pepsin by 29:571 Embelia schimperi 30:325 5-O-methylembelin from 30:325 Embryolethality 23:577 ofjervanes 23:577 of solanidanes 23:577 of spirosolanes 23:577 Embryonic central nervous system 30:378 role of serotonin (5-HT) in 30:378 Embryonic development 23:563-589 of Veratrum alkaloids 23:563-589 (+)-Emetine 18:330 amoebicidal activity of 6:485 EMIBD 24:954-956 bioactive compounds of 24:954-956 bioactivity of 24:954-956 Encephalitis 30:408 vaccination against 30:408 Encephalocele 23:570 Endocannabinoid analogues 30:198 as cannabinoid ligand 30:198 Endogenous defense signal system 25:397 Endogenous hepatoprotective factor 25:471 Endogenous peptide opioids 30:193 role of dynorphins 30:193 role of endorphins 30:193 role of enkephalins 30:193 role of nociceptin 30:193 role of OLR- 1 30:194 role of opioid receptors 30:193 Endophytic fungi 21:91;24:933-972 bioactivity of 24:944-950 brine shrimp toxicity of 24:944-950 Endoplasmic reticulum 25:548 Endoproteolytic proceesing 25:387 Endorphins 27:20,72,801 biological activity of 27:801 Endosymbiosis 6:134 Endothelial leukocyte adhesion molecule-1 (ELAM-1) 30:70
expression of 30:70 Endothelin antagonism 26:237 Endothelin converting enzyme (ECE) assay 28:699 activity of halistanol disulfate B in 28:699 Endothelium-dependent NO/EDFR 30:76 production of 30:76 Endothelium-Derived Relaxing Factor 26:951 Endotoxemia 25:463 Endotoxin-mediated pathway 23:140 Engorged toxicity 28:400 from Hib&cus rosa-sinensis 28:400 from Nicotiana tabacum 28:400 from Ocimum micranthum 28:400 from Quassia simarouba 28:400 from Ricinus communis 28:400 from Salvia serotina 28:400 from Spigelia anthelmia 28:400 from Symphytum officinale 28:400 from Stachytarpheta jamaicensis 28:400 Enkephalins 21:72;27:801;30:193,817 analgesic activity of 30:817 biological activity of 27:801 Enopeptins 21:374 Enveloped virus 21:662,665;30:395,401 inhibitor of 30:395 Enzymatic activities 24:981-1006,1077 alginasic 24:995-998 amylase 24:995-998 arabinosidasic 24:994-998 cellulasic 24:983-998 chitinasic 24:999-1001 galactosidasic 24:994-998 gelatinasic 24:999-1001 lipases 24:1005 lipasic 24:999-1001 nitrate reductases 24:999-1001, 1005 pectinasic 24:995-998 polysaccharides 24:1003-1004, 1009,1077 proteases 24:1005
1100 redox enzymes 24:983-987,1003 xylanasic 24:983-993 Enzymatic activity 21:168 Enzymatic hydrolysis 6:150;7:268,270; 13:54,56,57;16:291 of geniposide 16:291 of diacetylenic allo-xanthin 6:150 of soya bean flour 9:412,413 Enzyme 30:423,430,835,840 inhibition of 30:154-156 Enzyme activities 2:389,390,392,394, 396,399;21:748;23:12 Enzyme activity inhibition 21:589 Enzyme inhibition 24:845 biological activity 24:845 Enzyme inhibitors 22:29 Enzyme inhibitory activity 21:398,585; 27:850 Enzyme-inhibitory properties 7:14 Enzyme-linked immunosorbent assay 24:142;26:1125 Enzymes 23:377;27:378 activitiy of 27:378 coumarin effect on 23:335,356, 357,353,3 68,376,393,550,553 Enzymic activity 28:257 of plant polyphenols 28:257 Enzymic metabolism 23:12 24-epi- 1c~,25(OH)2D2 30:494 binding affinity of 30:494 10', 1 l'-Epiabsinthin (guaine sesquiterpene dimer) 29:574 effects on HIV- 1 protease 29:574 (+)-Epiaschantin 30:568,590,595 as platelet aggregation inhibitor 30:594 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:589 (-)-Epicatechin (2R,3R)-5,7,3',4'tetrahydroxyflavan-3-ol) 29:579 effects on ACE 29:579 Epicatechin 3-gallate (flavan-3-ol) 29:585
effects on proteasome CHYlike activity 29:585 (-)-Epicatechin 3-O-gallate 29:579 effects on ACE 29:579 (-)-Epicatechin-3-gallate (flavan-3-ol, gallotannin) 29:582 effects on collagenase 29:582 effects on MMP (gelatinase) 29:582 Epidermal growth factor 21:135;25:766 Epidermal growth factor receptor 27:847 Epidermoid carcinoma 25:266 Epigallocatechin ( 4 ~ 8 , 2[3~O-7)epicatechin 29:572 effects on HIV- 1 protease 29:572 Epigallocatechin (flavan-3-ol) 29:585 effects on proteasome CHYlike activity 29:585 (-)-Epigallocatechin 3-O-gallate 29:579,582,585,588 effects on ACE 29:579 effects on collagenase 29:582 effects on MMP (gelatinase) 29:582 effects on PEP 29:588 effects on proteasome CHYlike activity 29:585 Epilepsy 21:19;22:510-535,720,742 Delphinium denudatum Wall for 22:519 Abrus precatorius L for. 22:510 Acalyphafruticosa Forsk. For 22:510 Acorus calamus L. for 22:510 Albizzia harvey Fourn for 22:511 Allium cepa L. for 22:511 Aloe vera L. for 22:511 Alstonia scholaris R. Br. for 22:512 Alstonia venenata R. Br. for 22:512 Anagallis arvensis L. for 22:512 Annonidium monni for 22:512 Arisalema heterophyllum B. for 22:512 Arrabidaea platyphylla for 22:513
1101
Asparagus recemosus for 22:513 Bacopa monnieri L. for 22:513 Balsamodendron sp. for 22:513 Barringtonia recemosa for 22:514
Basilicum polystachyon for 22:514
Benincasa cerifera for 22:514 Benincasa cerifera savi for 22:514
Benincasa hispida for 22:513 Bersama abyssinica for 22:514 Bombax malabaricum DC. for 22:514
Bramia monnieri L. for 22:513 Brassica nigra L. for 22:514 Butea monosperma (Lam.) Kuntze for 22:514
Canscora decussata for 22:515 Canthium gueinzii for 22:515 Cardamine pratensis L. for 22:515
Cedrus odollam for 22:516 Centipeda orbicularis for 22:516 Cinnamomum camphora for 22:516
Cissus integrifolia for 22:517 Citrus maxima for 22:517 Cocculus sermentosus for 22:517
Colchicum luteum for 22:517 Colebrookea oppositifolia for 22:517
Coleus aromaticus for 22:517 Conium maculatum L. for 22:517
Conthium guiinzii for 22:515 Cucumis colocynthis L. for 22:518
Cucumis sp. L. for 22:518 Cynodon dactylon L. for 22:518 Cynodon dactylon L. Pets. for 22:518
Cyperus esculentus L. for 22:518 Cyperus rotundus L. for 22:401, 518
Daturafastuosa L.for 22:519, 742
Datura metel L. for 22:519
Daucus carota W. for 22:519 Deinbollia borbonica for 22:519 Delphinium denudatum Wall for 22:519
Dichrostachys cinerea L. for 22:519
Diospyros usmabarensis F. White for 22:520
Ekebergia senegalensis A. for 22:520
Elaeocarpus sphaericus for 22:520
Elaeocarpus tuberculantus for 22:520
Erythrina stricta for 22:520 Euphorbia nyikae Pax. for 22:520
Euphorbia tirucalli L. for 22:520 Euphorblaceae phyllantus for 22:720
Excoecaria agallocha L. for 22:520
Ferula alliacea for 22:521 Ferula galbaniflua for 22:521 Flemingia strobilifera for 22:521 Flueggea virosa for 22:521 Galium verum L. for 22:521 Galphimia glauca for 22:521 Gos~ypium herbaceum L. for 22:521,522
Gyrocarpus americanus Jacq. for 22:552
Helichrysum setosum for 22:522 Hemidesma indicus R. for 22:522
Hemidesmus indicus R. for 22:522
Herpestis monniera for 22:513, 522
Hesperethusa crenulata for 22:522
Hiptage benghalensis for 22:522 Hoslundia opposita for 22:523 Humboldtia vahliana for 22:523 Hyoscyamus niger for 22:523 Ilex aquifolium L. for 22:523 Impatiens repens for 22:523 Indigofera tinctoria L. for 22:523
1102
Ipomoea hederaceae L. for 22:523
Ipomoea hispida for 22:523 Launaea cornuta for 22:524 Leonurus cardiaca L. for 22:525 Limonia acidissima L. for 22:525
Limonia crenulata for 22:525 Lobelia inflata L. for 22:525 Maerua angolensis DC. for 22:525
Mangifera odorata L. for 22:525 Martynia annua L. for 22:526 Melissa officinalis L. for 22:526 Moghania strobilifera L. for 22:526
Moringa oleifera for 22:526 Musa paradisiaca L. for 22:526 Mylitta lapidescens for 22:527 Myrmicacin for 22:81,527
Nardostachysjatamansi DC. for 22:527
Nerium oleander L. for 22:527 Ocimum basilicum L. for 22:527 Origanum vulgare L. for 22:528 Ormocarpum kirkii for 22:528 Paeonia emodi for 22:528 Paeonia officinalis L. for 22:528 Palisota ambigua for 22:528 Paris polyphylla for 22:528 Phoenix reclinata for 22:529 Phyllanthus emblicata L. for 22:529
Phyllanthus urinaria L. for 22:529
Pongamsa glabra Vent. for 22:530
Psidium guyava L. for 22:530 Punica granatum L. for 22:530 Quercus infectoria for 22:530 Rabidaea platyphylla for 22:513 Rauwolfia serpentina L. for 22:531
Rauwolfia vomitoria L. for 22:531
Ruta graveolens L. for 22:531 Sapindus mukorossi for 22:531 Sapindus trifoliatus L. for 22:531
Saussurea lappa for 22:531 Scutellaria galericulata L. for 22:532
Semecarpus anacardium L. for 22:532
Solanum carolinense L. for 22:532
Solanum incanum L. for 22:532 Solunum xanthocarpum for 22:532
Stephania cepharantha for 22:533
Strychnos cinnamomifolia for 22:533
Synaptolepis kirkii for 22:533 Tamarix articulata for 22:533 Tamarix gallica L. for 22:533 Taxus baccata L. for 22:533 Terminalia chebula for 22:533 Trema guineensis for 22:534 Trema orientalis for 22:534 Trichosanthes anguins L. for 22:534
Valeriana hardwickii for 22:534 Valeriana officinalis L. for 22:534
Valeriana wallichii for 22:534 Xanthoxylon hostile for 22:535 Ximeni caffra for 22:535 Ximenia caffra for 22:535 Epileptic affections 22:517 Coleus aromaticus for 22:517 Epileptic attacks 22:526 Martynia diandra for 22:526 Epileptic children 30:377 Epileptic convulsive seizures 22:512 Annona muricata L. for 22:512 Epileptic fits 22:520,522,526,531 Elaeocarpus ganitrus for 22:520 Hiptage benghalensis for 22:522 Sapindus emarginatus L. for 22:531 Sapindus emarginatus L. for 22:531 Epileptic seizure 22:525 Leucas lavandulifolia for 22:525 (+)-Epimagnolin 30:568,590,595 as platelet aggregation inhibitor 30:594
1103
activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:589 Epingaione 28:402 growth regulatory activities of 28:402 3-Epi-paraherquamide A 28:354 anthelmintic activity of 28:354 (+)-Epipinoresinol dimethyl ether 26:241 as PAF-induced inhibitor 26:241 Epipolases kushimotoensis 25:898 Epipomolic acid (triterpene) 29:574 effects on HIV- 1 protease 29:574 Epithelizing effect 26:335 Epiyangambin 26:242 as PAF-induced inhibitor 26:242 (+)-Epiyangambin 30:569,590,593,595 activity in human cancer cell lines 30:589 activity in murine cancer cell lines 30:589 as platelet aggregation inhibitor 30:594 cytotoxic effect of 30:589 use of soft agar transformation assay 30:593 Epothilone 30:5 as microtubule stabilizing agent 30:5 Epothiolones 24:406 as anti-fungal agents 24:406 2 [3,5-Epoxy-5,10-dihydroxy-6c~ange lo y-lo xy-9 [3-isobutylo xygermacran-8ot, 12-olide 29:89 activity in iNOS assay system 29:89 activity in NFkB assay system 29:89 7 a, 8 c~-Epoxy- 6 or-hydro xyabieta9(11), 13-dien- 12-one 29:99 activity in EBV assay system 29:99 9,10or-Epoxy-9,10-seco-abieta-8,11,13trien-18-oic acid 29:99
activity in EBV 29:99 3,4-Epoxydehydroleucodin 29:90 activity in NFkB assay system 29:90 (7S)-413,5c~-Epoxygermacr- 1(10)E-en213,613-diol 29:88 activity in PLA assay system 29:88 activity in TPA assay system 29:88 4[3,15-Epoxymiller-9E-nolide 29:89 activity in NFkB assay system 29:89 activity in TNF~ assay system 29:89 413,15-Epoxymiller-9Z-enolide 29:89 activity in NFkB assay system 29:89 Epoxypironetin 30:27,28 as mitotic arrester 30:27 effect on G2/M phase 30:28 7,8-Epoxyzahavin A 29:103 activity in AOS bioassay system 29:103 Epstein-Barr virus (EBV) 24:215,849; 25:45;30:394,592 in raji cells (EBV genomecarrying human lymphoblastoid cells) 30:592 Epstein-Barr virus early antigen 21:642; 24:215-217;25:46;30:592 activation inhibition of 30:592 inhibition of 25:46 Epstein-Barr virus inhibition 30:560 due to lignans 30:560 due to isoquinoline alkaloids 30:560 Equisetin 28:121 antibiotic activity of 28:121 cytotoxicity of 28:121 HIV inhibitory activity of 28:121 ER ryanodine receptor Ca 2+ channels 25:517 Ergolide 29:90 activity in COX assay system 29:90 activity in NFkB assay system 29:90
1104
activity in iNOS assay system 29:90 Ergosterol 28:570,572 as antitumor substance 28:570 effect on neovacularization 28:572 Ergosterol mutants 25:304 of Nenrasapora crassa 25:304 Erioc itrin (5,7,3 ',4'-tetrahydroxyflavanone-7-O-rutinoside) (flavanone O-glycoside) 29:579 effects on ACE 29:579 Eriosema compound B (prenylated xanthone) 29:579,581 effects on ACE 29:579 effects on NEP 29:581 Erythrinin B 28:229 biological activity of 28:229 Erythrodiol (triterpene) 29:586 effects on LELA 29:586 Erythromycin A 11:196,197 biological activity of 12:48 Erythropoietin (EPO) 29:547 antibodies against 29:547 as hormone 29:547 in red blood cells production 29:547 inhibition of 29:548 Escherichia coli 30:739,843 antibacterial activity against 30:739 antifungal activity against 30:739 biological activity of 30:843 Escins (triterpene saponin) 29:574 effects on HIV- 1 protease 29:574 Eseramine 25:536 as immunosuppressive drug 25:536 Eseridine 25:536 as immunosuppressive drug 25:536 Essential oil 21:596;28:412,415,427, 390,408,421,426 acaricidal activity of 28:412,427 against sarcoptic mange 28:415 antimicrobial activity of 21:235 lethality tests of 28:392
use as bactericides 28:390 use as fungicides 28:390 use as insecticides 28:390 Estradiol 26:222 Estrogen agonist/antagonist properties 26:210 of secoisolariciresinol diglycoside 26:210 Estrogen hormones 9:411 Estrogen responsive kidney 5:447 Estrogenic activity 21:759;23:353 of coumarin 23:335,356,357, 353,368,376,393,550,553 26:760 Estrogenic activity Estrogen-like activity 28:227 of phenols from moraceous plants 28:227 of Glycyrrhiza species 28:227 Estrogen-receptor antagonists 25:797 Ethanol 25:966 LTP-blocking effect of 25:966 Ethnomedical uses 23:652 of celastraceae 23:652 Ethnopharmacology 13:640 13-Ethoxylabda-8(17), 11,14-trien- 19oic acid N-(methyl)phthalamide 29:101 activity in EBV bioassay system 29:101 Ethyl phenylpropiolate (EPP) induced edema 25:46 7-O-Ethylrosmanol (abietane diterpene) 29:575 effects on HIV- 1 protease 29:575 Etoposide 26:160-163,171,172,212,213 cytotoxicity of 26:213 use in combination therapy 26:171 Etoposide phosphate 26:160 in lymphoid cancer 26:171 in myeloid leukemia 26:171 in refractory testicular cancer 26:171 in stomach cancer 26:171 in ovarian cancer 26:171 in brain cancer 26:171 in breast cancer 26:171
1105 in pancreatic cancer 26:171 in small/non-small lung cancer 26:171 Eucalyptus blakelyi 29:111 activity in EBV bioassay system 29:111 Eucalyptus camaldulensis 28:427 acaricidal activity of 28:427 Eucalyptus grandis 29:111 activity in EBV bioassay system 29:111 activity in lung-2 bioassay system 29:111 activity in skin-1 bioassay system 29:111 activity in skin-3 bioassay system 29:111 Eucaryote signals-regulated protein kinase (PK's) 25:521,522 (2S)-Euchrenone 28:17 as aromatase inhibitor 28:17 Eudesmanes 29:87 activity in EBV bioassay system 29:87 [3-Eudesmol 29:87 activity in AM assay system 29:87 Eugenol 28:403 acaricidal activity of 28:403 Eugenol 28:426 as bioactive monoterpenoid 28:426 Euglobals 29:111 activity in EBV bioassay system 29:111 Eukaryate signal transduction components 25:512 inhibition of 25:512 Euonymine 29:88 activity in EBV assay system 29:88 Euphorbia obovalifolia's latex 28:400 acaricidal properties of 28:400 Euphoria 21:101 Euscaphic acid 29:575 effects on HIV- 1 protease 29:575 Euthyneura 21:3
Excisanin A 29:101 activity in EBV bioassay system 29:102 activity in NFkB bioassay system 29:101 activity in NO bioassay system 29:101 constiutents activity in skin-1 bioassay system 29:102 Excoecarin D 29:100 activity in EBV assay system 29:100 Excoecarin E 29:100 activity in EBV assay system 29:100 Excoecarin M dimethyl ester 29:101 activity in EBV bioassay system 29:101 Excoecarin-N-dimethyl ester 29:100 activity in EBV assay system 29:100 Exoerythrocytic cycle 26:781 Expectorant 17:451 Expectorant activities 21:633 Expectorant activity 28:200 of genus Morus 28:200 Extracellular promastigote 26:790 toxicity assays for 26:790 Extracellular signal regulated kinases 25:526 Extracts of Geranii 27:414 effects on serum total cholesterol 27:414 Eye fatigue 30:64 use of carp in 30:64
Factor-a-dependent inflammatory liver injury 25:459 Falcipain 25:331 inhibition of 25:331 Fangchinoline (bisbenzylisoquinoline) 29:578 effects on ACE 29:578 Faradiol (taraxast-20-ene-3[3,16[3diol) 29:586 effects on CHY 29:586 Faradiol 3-O-myristate (taraxast-20-
1106
ene-3 [3,1613-diol 3-O-myristate) 29:586 effects on CHY 29:586 Fargesin 26:241 as PAF-induced inhibitor 26:241 Farnesyl-protein transferase 24:403-464 as natural product inhibitor 24:403-464 for cancer chemotherapy 24:403-464 Fat cell 27:393 biological activity of 27:393 Fatty acid antileukemic activity of 7:24 FeC13-induced epilepsy 22:509 Felbamate 22:508 Feline leukemia virus (FeLV) 21:646 Fenfangjine A (bisbenzylisoquinoline) 29:578 effects on ACE 29:578 Fertility regulation 13:658 Fertility-regulating agent 13:658 Fever 22:532 Sida cordifolia L. for 22:532 Feverfew 13:660 Fibrinogen 30:834,838 conversion of 30:834 fibrin from 30:834 Fibrinolysis rate 30:841 effect of G-90 30:841 Fibrinolytic activity 21:670;30:826,827 from earthworm Eisenia fetida 30:826 Fibrinolytic agent 30:839 in disease prevention 30:839 in treatment of clotting disease 30:839 in acute myocardial infarction 30:839 in cerebral thrombus 30:839 Fibrinolytic effect 30:840 of lyophilized powder 30:840 Fibrinolytic efficacy 30:839 in vitro 30:839 Fibrinolytic enzyme 30:825,827,839 from Lumbricus rubellus 30.'825 from Lumbricus bimastus 30:827 in thrombosis treatment 30:839 recombinant prourokinase (pro-
UK) as 30:839 recombinant tissue-type plasminogen activator as 30:839 staphylokinase as 30:839 streptokinase (SK) as 30:839 urokinase (UK) 30:839 Fibrinolytic mechanism 30:837 Fibrinolytic medicine 30:842 activity of 30:842 half life of 30:842 immunogencitity of 30:842 properties of 30:842 re-occlusion rate of 30:842 Fibroblast growth factor 30:56 angiogenesis by 30:56 Ficus brachypoda's latex 28:400 acaricidal properties of 28:400 Field-collected samples 29:254 cytotoxic activity of 29:256 F-II cleavage 30:838 of human plasminogen 30:838 F-III- 1 30:826,828,830,833,836 caseinolytic activity of 30:833 inhibition by Soybean trypsin inhibitors (SBTI) 30:836 inhibition of 30:836 N-terminal sequences of 30:828 F-III-2 30:826,828,830,833 fibrinolytic activity of 30:833 Filipin 24:548 antiviral microbial-derived compound 24:548 Fisetin (3,7,3',4'-tetrahydroxyflavone) (flavonol) 29:579 effects on ACE 29:579 Fisetin (5-deoxy-quercetin; 3,7,3',4'tetrahydroxyflavone) 29:572,581 effects on HIV- 1 protease 29:572 effects on NEP 29:581 Fisetin (flavonol) 29:582,585 effects on LELA 29:585 effects on MMP 29:582 Fish oils 28:566 anti-tumor activity of 28:566 Fits 22:518,524 Cuscuta europea L. for 22:518 Jatropha curcas L. for 22:524
1107
Fits in children 22:531 Ruta graveolens L. for 22:531 FK 508 25:464 as immunosuppressive drug 25:464 FL3-27 gene proprotein 29:592 effects on cysteine protease 29:592 Flavonoids 25:607;27:425,504;30:56, 70,233,234,238,241,272-277, 284-285,619,628,629,724,725,562 activity of 27:504 against Staphyllococcus aureus 30:629 anti-thrombic actions of 30:70 biological activity of 27:425 effect on prostaglandin Ezdependent cytoprotection 25:607 inhibitory activity of 30:629 wound-healing effect of 30:628 Flavopiridol 21:153 anticancer activity of 21:135,136 clinical usage of 21:138 Flavopiridol-induced cytotoxicity 21:136 Flavors 13:322-345 analysis of 13:322-345 biogeneration of 13:295-345 5-Flourouracil (5FU)-induced lethality 25:447,448 protective effect 25:447,448 Flu 30:691 Maytenus amazonica for 30:691 Fluorescent antibodies 30:841 Fluorinated probes 27:333 activity of 27:333 5-Fluorouracil (5-FU) 25:447,448; 27:795,436 ;28:562,559 as cancer drug 28:559 gastrointestinal toxicity by 28:562 immunotoxicity by 28:562 levels in mice plasma 28:567 myelotoxicity by 28:562 prophylactic effect against mylosuppression 25:447,448 5-Fluorouracil-induced myelosuppression 25:429
FMDV 24:524 activity of actinoplanic acids against 24:524 Foliol 29:100 activity in NFkB bioassay system 29:100 Folk medicine 28:202;30:203,603 from genus Hypericum 30:603 use of Artocarpus venenosa in 28:202 use of ginseng root in 30:203 Follicle-stimulating hormone 27:796 Food mutagens 8:378,388,389 Forest tent caterpillar 24:865 bioassay of 24:865 Formaldehyde induced arthritis 25:46 Formalin 30:205 inflammatory pain induction by 30:205 neurogenic pain induction by 30:205 Formalin test 30:207 activity of 13-narin-II8-4'-OMeeridictoyol in 30:207 Formaononetin 28:228 biological activity of 28:228 Formic acid 28:384 as miticide 28:384 Formononetin 28:224,241 anti-microbial activity of 28:224 anti-Helicobacter pylori activity of 28:241 7-Formyldehydrohernangerine 30:563, 589 activity in human cancer cell lines 30:589 cytotoxic effect of 30:589 from genus Hernandia 30:563 from Hernandia nymphae!/blia 30.563 7-Formyldehydronornantenine 30:563, 589 activity in human cancer cell lines 30:589 activity in murine cancer cell lines 30:589 cytotoxic effect of 30:589 (+)-N-Formyldehydroovigerine 30:563, 589
1108 activity in human cancer cell lines 30:589 activity in murine cancer cell lines 30:589 cytotoxic effect of 30:589 7-Formyldehydroovigerine 30:589 activity in human cancer cell lines 30:589 activity in murine cancer cell lines 30:589 cytotoxic effect of 30:589 N-Formylnornantenine 30:563 from genus Hernandia 30:563 from Hernandia sonora 30:563 (+)-N-Formylnomantenine 30:563,589 activity in human cancer cell lines 30:589 activity in murine cancer cell lines 30:589 cytotoxic effect of 30:589 (+)-N-Formylovigerine 30:563,582,589 activity in human cancer cell lines 30:589 activity in murine cancer cell lines 30:589 cytotoxic effect of 30:589 Forscarnet 24:486,487 as anti-viral agent 24:486,487 Forskolin 10:183;13:659;29:102 activity in APO bioassay system 29:102 Forsythia suspensa 24:855 inhibition of cyclic adenosine monophosphate (c-AMP) phosphodiesterase 24:855 Fortunellin (5-hydroxy-7-glucosylrhamnosyl-4'-methoxyflavone) 29:572 effects on HIV- 1 protease 29:572 Forward mutation test 27:303 Fostreus 27:883 as phosphatase inhibitor 27:883 FPTase inhibition 24:403-464 by andrastins 24:452,453 by arteminolide 24:457 by desmethoxy streptonigrin 24:454 by gliotoxin 24:452
by lupane triterpenoides 24:457 by monoterpenes 24:461 by patulin 24:458 by rhombenone 24:456 by saquayamycnis 24:480 by SCH 24:58,207,278,450,451 by solandelactones 24:455 by valinuoctins 24:459 FPTase inhibition 24:444 FPTase inhibitor 24:439 cembranolide as 24:439 FPTase inhibitors 24:403 Fragrant odor 2:278 of liverworts 2:278 Fraxinus ornus 26:334 antimicrobial activity of 26:334 Fredericamycin A antitumor agent 16:27 antitumor antibiotic 16:27 synthesis of 16:27-74 Free fatty acid 27:404 biological activity of 27:404 Free radical scavenging activity 22:314 Free radicals 30:221,224 role in aging 30:224 role in atherosclerosis 30:224 role in cancer 30:224 role in cardiac diseases 30:224 role in diabetes 30:224 role in human diseases 30:224 role in inflammation 30:224 role in intestinal diseases 30:224 role in neurodegeneration 30:224 role in reperfusion injuries 30:224 role in respiratory disorders 30:224 5-FU (5-flourouracil) 25:450,453 5-FU plus carp oil 28:566,568 effects on tumor growth 28:566 in sarcoma 180-bearing mice 28:566 5-FU plus tuna oil 28:566,568 effects on tumor growth 28:566 in sarcoma 180-bearing mice 28:566 5-FU treatment 25:449 Fucoidan 30:55-57,399,405 against human CMV 30:405
1109 antitumor activity of 30:56 as antiviral agent 30:405 effect on angiogenesis 30:56 effect on body 30:56,57 effect on liver metastasis 30:55 effect on spleen or adipose tissue weight 30:56,57 effect on thymus 30:56,57 effect on tumor growth 30:55-57 from Fucus vesiculosus 30:399 from Laminariajaponica 30:56 5-FU-induced adverse effect 25:449 5-FU-induced suppression of bone marrow hematopoiesis 25:454 Fukiic acid (phenolic acid) 29:582 effects on collagenase 29:582 Fukinolic acid (phenylpropanoid ester) 29:582 effects on collagenase 29:582 Functional bioactivity 30:813 of [Tyr)Me)2-Phe] peptides 30:813 of Tyr(Me)z-Phe-NH2 30:813 of d-Tyr(Me)z-Phe-NH2 30:813 of Tyr(Me)z-d-Phe-NH2 30:813 of d-Tyr(Me)z-d-Phe-NH2 30:813 of Tyr(Me)z-Phe-G-V-V-NH2 30:813 of d-Tyr(Me)2-Phe-G-V-V-NH2 30:813 of Tyr(Me)2-d-Phe-G-V-V-NH2 30:813 of d-Tyr(Me)2-d-Phe-G-V-VNH2 30:813 Functional bioassay 30:809 activity of Tyr-Tic-NH2 in 30:809 activity of (Tic 2, LeuS)enkephalin in 30:809 activity of (Tic2)dermorphin in 30:809 activity of (tic2)DYN-A-(1-11)NH2 in 30:809 activity of (D-Ala,desGly2)DYN-A-(1-11)-NH2 in 30:809 activity of DYN-A-(1-11)-NH2 in 30:809
activity of (tic2)DYN-A-( 1- 13-)NH2 in 30:809 Fungal toxin 1:289 synthesis of 1:289 Fungicidal activities 17:243 ;21:182, 192,266,275,276,277,285 ;28:146 of eliamid 28:146 Fungicidal properties 21:225 Fungicidal saponins 7:433 Fungicides 9:226;28:390 used of essential oil 28:415,390 Fungistatic activity 21:189,238 Furanodiene 29:88 activity in HPT assay system 29:88 activity in COX assay system 29:87 activity in iNOS assay system 29:87 activity in NFkB assay system 29:87 activity in NO assay system 29:87 activity in TPA bioassay system 29:103 Furofuran lignans 30:594 antiplatelet activity of 30:594 Furosin 30:208 analgesic effect of 30:208 Fusarium toxins 9:201-208 G-90 30:841 as c~plasminogen activator 30:841 GABA 21:84;25:30,536,537;30:627, 782,783,787 effect on blood pressure 30:783 effects of glutamic acid decarboxylase (GAD) 30:783 effects of hyperforin inhibitor 30:627 hypotensive effect of 30:782 in spontaneously hypertensive rats 30:783 in systolic blood pressure in SHR 30:783 GABA agonist 25:528 GABA antagonists 21:69
1110 GABA receptors 21:69,95;25:531 GABAA 21:672,673;22:666 GABAA receptor 25:529,895 GABAB receptor 25:530;30:203,787 effect in SHR 30:787 G-protein-linked receptor type 25:530 interaction with ginseng 30:203 GABA gated Cl-channels 25:528 GABA transporter 25:537 GABAA receptor 21:14,19,101,269,270; 30:203 interaction with ginseng 203 GABAB 21:14,672;22:666 GABAB receptor 21:20 GABA-benzodiazepin-chloride channel receptor 21:672 GABA-ergic neuroreceptors 21:5 GABA-ergic receptor 21:68 Gabapentin 22:508 GADPH 21:229 Galactose prodrugs 21:161 biological behaviour of 21:161 [3-Galactosidase 7:40 reactivation by [3-galactoside analogue 7:40 inhibition by aminoglycopyranoses 7:47 inhibition by conduritol C cisepoxide 7:38 inhibition by conduritol C transepoxide 7:38 inhibition by J3-galactosyl amines 7:44 inhibition by nitrophyenylthiogalactoside 7:48 Galactosidasic 24:999-1001 enzymatic activity 24:999-1001 Galactostain 7:41,42,267 mammalian J3-galactosidase inhibitor of 10:542 Galanin receptor antagonists 27:799 Gallic acid 30:208 analgesic effect of 30:208 Gallocatechin 3-gallate (flavan-3-ol) 29:585 effects on proteasome CHYlike activity 29:585
Gal-N cyctotoxicity 21:656 Gancaoinin S 28:228 biological activity of 28:228 Gancaonm C 28:228 biological activity of 28:228 Gancaonin E 28:228 biological activity of 28:228 Gancaonin G 28:228 biological activity of 28:228 Gancaonin H 28:228 biological activity of 28:228 Gancaonin I 28:224 anti-microbial activity of 28:224 Gancaonm I 28:228,243 anti-Helicobacter pylori activity of 28:243 biological activity of 28:228 Gancaonin O 28:228 biological activity of 28:228 Gancaonin P 28:228 biological activity of 28:228 Gancaonin Q 28:228 biological activity of 28:228 Gancaonin R 28:226 anti-human immunodeficiency virus (HIV) activity of 28:226 Gancaonin R 28:228 biological activity of 28:228 Gancaonin U 28:228 biological activity of 28:228 Gancaonin V 28:228 biological activity of 28:228 Gancaonin Y 28:228 biological activity of 28:228 Gancaonol B 28:224,243 anti-Helicobacter pylori activity of 28:243 anti-microbial activity of 28:224 Gancaonol C 28:243 anti-Helicobacter pylori activity of 28:243 Ganciclovir 21:698;24:474,486 as anti-viral agent 24:474,486 synergistic interaction with 21:698 Ganglionic-type nicotinic receptor 21:95
1111 Ganoderic acid F (12-acetoxy-3,7,11,15, 23-pentaoxolanost-8en-oic acid) 30:64 angtiangiogenic effects of 30:63 13C-NMR of 30:64 effects of 30:63 effects on hemoglobin 30:63 Ganoderma lucidum 30:56,58,60 antimetastatic effect of 30:58,60 antitumor effect of 30:58 effect on blood glucose 30:58 in treatment of arteriosclerosis 30:58 in treatment of arthritis 30:58 in treatment of bronchitis 30:58 in treatment of cancer 30:58 in treatment of diabetes 30:58 in treatment of hyperlipidemia 30:58 in treatment of hypertension 30:58 Gardenin A (flavone) 29:572 effects on HIV-1 protease 29:572 Garlic 23:455,467 supercritical fluid extraction of 23:467 Gastric acid secretion 21:701 inhibitory effect on 21:701 St-4 Gastric carcinoma 19:298 Gastric H+,K+-ATPase 25:612 Gastric tubing 27:314 for gastrointestinal absorption 27:314 Gastrin receptor 25:611 Gastrin releasing peptide 27:800 Gastritis 17:137 Gastrointestinal cancer 1:275 Gastrointestinal depression 30:799 due to analgesic alkaloid 30:799 Gastrointestinal diseases 30:56,691,747 use of Maytenus amazonica for 30:691 Gastrointestinal disorder 25:607 effect offlavonoids 25:607 flavonoids 25:607,615 effect on gastrointestinal disorder of 25:607,615 Gastrointestinal hormones 27:794
Gastrointestinal peptide-hormones 27:797 Gastrointestinal toxicity 27:436;28:559, 560-562;30:56 by doxorubicin 28:562 chitosan inhibitory effect on 28:561 due to cancer drugs chemotherapy 30:56 of5-fluorouracil (5-FU) 28:560 of bilobalide 28:171 of chitosan 28:559 of fish oils 28:559 Gastroprotective agents 25:614 Gaucher's disease 7:39 Gaudichandioside A 27:14,24,25; 30:734 against certain cancer cells 30:734 medicinal uses of 27:447 Gelatinasic 24:999-1001 enzymatic activity 24:999-1001 Gene experession control 5:580,581 Gene expression 30:373 by antisense RNA 13:257-261 in regulation of methyl CpG binding protein 30:373 natural regulation of 13:257-261 Gene SLC18A2 30:380 role in vesicular monoaminetransporter type 2 (VMAT2) 30:380 Genetic duplication 30:370 of ancestral gene 30:370 Genistein (4',5,7-trihydroxyisoflavone) 29:577 effects on aminopeptidase N 29:577 Genital warts 30:405 Genkwanin 26:219 as chemopreventive agent 26:219 Genotoxic agent 30:316 from Rubia tinctorum L. 30:316 Genotoxicity assays 26:675 Gentiopicroside 25:471 effect ofgentiopicroside 25:471 serum ALT activity of 25:471
1112
Genus dorstenia (Moraceae) 29:761 analgesic activities of 29:761 anti-infective principles from 29:761 anti-inflammatory activities of 29:761 anti-oxidant activities of 29:761 anti-rheumatic remedies from 29:761 anti-snakebite principles from 29:761 cytotoxic activities of 29:761 in skin diseases 29:762 pharmacology of 29:761 to treat rattlesnake bites 29:765 Genus Morus 28:200 anti-inflammatory activity of 28:200 anti-tussive activity of 28:200 anti-pyretic activity of 28:200 Geranii herba 27:413,415 biological activity of 27:413,415 Geraniin 30:208 analgesic effect of 30:208 Geraniin (hydrolysable tannin) 29:572 effects on HIV-1 protease 29:572 Geraniol 28:406,426;29:83 acaricidal properties of 28:406 activity in ODC assay system 29:83 activity in RAS assay system 29:83 as bioactive monoterpenoid 28:426 3-Geranyl-2,4,6-trihydroxy-benzophenone (phenolic ketone) 29:571 inhibition of Candida albicans aspartic protease 29:571 (E)-Geranylacetone 28:406 acaricidal properties of 28:406 (7S)-Germacra- 1( 10)E,4(15)-dien2~,5ot,613-triol 29:88 activity in TPA assay system 29:88 activity in PLA assay system 29:88
(7S)-Germacra-4( 15)Z,9-diene- 1c~,2 [~, 6[3-triol 29:88 activity in TPA assay system 29:88 Germacrane 29:88 activity in CRG assay system 29:88 activity in HPT assay system 29:88 Gibberellenic acid growth effect on root culture 17:425 Gingerol 24:900 as an accelerator of the motility of digestive organs 24:900 as an antiemetic agent 24:900 effect of gingerol analogues on NA-contraction 24:902 effect of gingerol analogues on PGF2~- contraction 24:902 related compounds 24:900-902 Ginkgo biloba L. 28:165,170,177,179 anti-depressant effect of 28:177 anti-oxidant activity of 28:179 anti-stress effects of 28:177 biological activities of 28:165 Ginseng 13:660;30:203 activity in chronic pain model 30:203 as analgesic 30:203 interaction with bradykinin B2 receptor 30:203 interaction with GABAA receptor 30:203 interaction with GABAB receptor 30:203 interaction with neurokinin NK~ receptor 30:203 Ginseng root 30:203 use in abdonminal pain 30:203 use in chest pain 30:203 use in folk medicine 30:203 use in neuralgia 30:203 use in pain 203 use in toothache 30:203 Ginseng saponins 30:203 action of 30:203
1113 Ginsenoside Rg~ 27:424 biological activity of 27:424 Ginsenosides 30:203 action of 30:203 effect on central nervous system 30:203 effect on nociception 30:203 effect on spinal region 30:203 effect on supraspinal region 30:203 voltage-sensitive calcium channels blockade by 30:203 GL-311 26:162 used for anticancer treatment 26:162 Glabranin 28:228 biological activity of 28:228 Glabrene 28:224,228 anti-Helicobacter pylori activity of 28:241 anti-microbial activity of 28:62,224,228,257,293 biological activity of 28:228 Glabridin 28:228,241 anti-Helicobacter pylori activity of 28:241 anti-microbial activity of 28:224 biological activity of 28:228 Glabrocoumarone A 28:229 biological activity of 28:229 Glabrol 28:228 biological activity of 28:228 Glial cell 27:806 Glioma cells 27:797 Gliotoxin 24:452,545 antiviral microbial-derived compound 24:545 FPTase inhibition by 24:452 Glisoflavanone 28:228 biological activity of 28:228 Glucocorticoids 25:463,516 D-Glucopyranosyl moiety 30:813 pharmacological activity of 30:813 13-Glucoronidase inhibitor 25:263 ~-Glucosidase 2:379,352,514,526,567; 10:568,249,250;19:357,365,369 3,8-diepialexine inhibition with 7:14
6-epi-castanospermine inhibition with 7:12 australine inhibition with 7:15 castanospermine inhibition with 7:12 DMDP inhibition with 7:15 inhibition by 2-deoxy-2-fluoro-~D-glucopyranoside 7:36 inhibition by acarbose 7:47 inhibition by conduritol B epoxide 7:38,39 inhibition by nojirimycin heptitol derivative 7:43 inhibition by validamycin 7:47 cx-Glucosidase inhibition 21:592 [3-Glucosidase inhibitor 19:369 Glucosidase inhibitors 22:30 ot-Glucosidase inhibitors 7:46,48; 13:235-246;10:496 c~-Glucosidase inhibitory activity 21:592 [3-Glucosidases 27:778 biological activity of 27:778 Glucuronic prodrugs 21:169 biological behaviour of 21:169 [3-Glucuronidase activity 21:177 Glucuronides 28:288 in urine 28:288 Glutamate (N-methyl-D-aspartate receptor (NMDA) 25:519 Glutamate receptors 30:208 Glutamate transporters 25:536 Glutamic pyruvic transaminase 25:935 Glutamine 25:320 Glutathione reductase inhibition 26:1036 Glutathione 5-transferase (GST) activity 21:585 Glutathione S-transferase 21:356 Glutinol 21:690 Glyasperin A 28:226,228 anti-human immunodeficiency virus (HIV) activity of 28:226 biological activity of 28:228 Glyasperin B 28:228 biological activity of 28:228 Glyasperin C 28:228 biological activity of 28:228
1114 Glyasperin D 28:224,228,243 anti-Helicobacter pylori activity of 28:243 anti-microbial activity of 28:62,224,257,293 biological activity of 28:228 Glyasperin J 28:228 biological activity of 28:228 Glyasperin K 28:228 biological activity of 28:228 Glyceraldehyde-3-phosphate dehydrogenase 21:229 Glycerol-3-phosphate dehydrogenase inhibitory activity 21:591 Glycine receptors 25:530 Glycine-gated Cl-channels 25:530 Glyco analogues activity 30:817 in vivo 30:817 Glycoalkaloids 7:427 molluscicidal activity of 7:427 Glycolysis (GADPH inhibition) 26:924 Glycopeptide antibiotics 10:657-669 Glycoproteins 29:547 erythropoietin as 29:547 myeloma protei 9 as 29:547 Glycosidase activity 28:281 ofpolyphenols 28:281 Glycoside naringin 28:288 in urine 28:288 Glycosyl pyridinium salts 7:57 13-glycosidases inhibition by 7:57 O-Glycosylation 30:814 role in 8 receptor affinity 30:814 role in ~ receptor affinity 30:814 Glycycoumarin 28:228 biological activity of 28:228 Glycyrdione A 28:228 biological activity of 28:228 Glycyrin 28:224,228,243 anti-Helicobacter pylori activity of 28:243 anti-microbial activity of 28:224 biological activity of 28:228 Glycyrol 28:224,226,241 anti-Helicobacter pylori activity of 28:241
anti-human immunodeficiency virus (HIV) activity of 28:226 anti-microbial activity of 28:224 biological activity of 28:228 Glycyrrhetic acid 28:241 anti-Helicobacter pylori activity of 28:241 18-[3-Glycyrrhetinic acid (glycyrrhetic acid) 29:586 effects on LELA 29:586 Glycyrrhiza species 28:223,226 anti-HIV flavonoids from 28:226 bioactive phenolic compounds from 28:223 Glycyrrhizic acid 28:241 anti-Helicobacter pylori activity of 28:241 Glycyrrhizin 24:151,880-883;25:90, 99,103,465,467 as neuromuscular blocker 24:880-883 hepatoprotective effect of 25:466 Glycyrrhizin (triterpene saponin) 29:586 effects on thrombin interactions 29:586 Glyfoline 13:375-380 antitumor activity of 13:375-380 Glyinflanin A 28:228 biological activity of 28:228 Goiazensolide 29:89 activity in NFkB assay system 29:89 Gomisin M 26:240 as PAF-induced inhibitor 26:240 Gonadotrophic cycle 22:376 Gonadotropin hormone 27:795 Gonadotropin-releasing harmone 27:795,796 Gonadotropins 27:796 Goniodomin A 19:578 antifungal activity 19:578 antifungal metabolite 19:578 (6R)-(+)-Goniothalamin antifungal activity of 19:479 antitumor activity of 19:479 insect antifeedant activity of 19:479 isolation of 19:481
1115 plant growth inhibitory effect of 19:479 Gonorrhea 22:607,608 Gossypin (gossypetin 8-O-glucoside, 3,5,7,8,3',4'-hexahydroxyflavone 8O-glucoside) 29:572 effects on HIV- 1 protease 29:572 Gossypol (dimeric sesquiterpene) 29:586 effects on acrosin, azocoll proteinase 29:586 GPI assay 30:807,812 activity of k-agonist U-50,488 in 30:807 activity of Tyr-(Me)2-D-Phe-GlyVal-Val-NH2 in 30:812 activity of Tyr-(Me)z-D-Phe-NH2 in 30:812 GPI bioassay 30:814 activity of glycopeptide in 30:814 G-protein 30:383 effects on inositol phosphate hydrolysis 30:383 elevation of cytosolic Ca ++by 30:383 inhibition of cAMP formation by 30:383 G-protein coupled receptors G-protein coupled-receptor 27:825; 30:383,384 association with behavioral phenotypes 30:384 G-protein-linked receptors 25:530,531, 539 GR133487 (5,5-trans-fused cyclic lactone euphane triterpene) 29:586 effects on cx-chymotrypsin 29:586 effects on cx-thrombin 29:586 effects on factor XIa 29:586 effects on plasmin 29:586 effects on trypsin 29:586 Gram negative bacteria 21:430,435,599, 600,607,610 Gram positive anaerobic bacteria 21:607
Gram positive bacteria 21:186,235,401, 403,404,405,414,599,607 Gram-negative bacteria 30:693 Maytenus species against 30:693 Gram-positive bacteria 23:68;30:629, 693 actamycin against 23:68 antimicrobial activity of 30:629 inhibitor of 23:68 Maytenus species against 30:693 Grandiflorolic acid 29:100 activity in EBV bioassay system 29:100 Grandiflorolic acid angelate 29:100 activity in EBV bioassay system 29:100 Grandisin 26:230 trypanosomicidal activity of 26:230 Grandmal seizures 22:508 Granulocyte phagocytosis 26:47,55 ofjenisseensosides C 26:47,55 ofjenisseensosides D 26:47,55 Green tea 27:417,420 biological activity of 27:417,420 Gringerol 24:900-902;25:757 effect of general analogues on PGF2 NA- induced contraction 24:902 Griseofulvin 24:934 as anti-fungal agents 24:934 Griseofulvin 25:757 Grob-type fragmentation 24:728,731 Growth 30:61 of tumor cells 30:61 Growth inhibition 17:142 Growth inhibitor activity 7:407, 416-419,423 ;23:297;24:859 of cyclocolorenone 24:859 of samaderines 23:297 GTP-bound stimulatory G protein 25:262 Guaiazulene 5:363,369 as an anti-inflammatory agent 14:315 Gugulipid 5:715,716 Guidimacrin 27:831 antitumor mechanism of 27:831 Guillain-Barre syndrome 22:584
1116
Guinea-pig ileum bioassay 30:802 activity of ~t-opioid receptor in 30:802 in vitro 30:802 Gurmarin 27:42 as sweetness inhibitor Gymnemasaponins III-V 27:41,43 as sweetness inhibitors 27:41 Gymnemic acid I-VI,VIII,XVIII 27:41, 43,44 as sweetness inhibitors 27:41 Gymnemic acids biological activity of 18:670-674 Gynandropsis gynandra 28:395 repellent properties of 28:395 Gypsophila 26:55 of adjuvant activity 26:55 Gypsophila paniculata 26:41,53 hemolytic activity of 26:41 spermicidal activity of 26:53 Gypsophila saponins 26:55 imunomodulatory effect of 55 Gypsy moth 24:865 bioassay of 24:865 Gyrostroma missouriense 15:351,383 H § K+-ATPase 25:613 H*/K+-ATPase inhibitor 25:612;28:676 hexaprenyl-hydroquinone sulfate as 28:676 H 1V inhibitors 25:942 H2 receptors 25:612 H202-induced apoptosis 25:269 HA 26:1002-1004 antibacterial activity of 26:1002 as a carcinogen 26:1002-1004 HA inhibitors 27:116-129 2 [3-chlori-peracetyl-Neu methyl ester 27:124,127 4-(8-morpholin) capriloylNeu5Ac-c~2Me 27:126,127 4,7- di- O- ace tyl-Neu5 Ac- c~2Me 27:123 4-capriloyl-Neu5Ac-cx2Me 27:125-127 4-O-acetyl-Neu5 Ac-c~2Me 27:123 4-O-capriloyl-Neu5 Ac-2Me 27:125
4-O-phenyl-2-propionylNeu5Ac-cx2Me 27:123 4-t-butyl-dimethyl-silyl ether 27:127 5-azido-5-deamino-Neu5Acc~2Me 27:119 5-N-benzyloxycarbonyl-Neucx2Me 27:119 5-N-propionyl-Neu-c~2Me 27:119 7-deoxy-Neu5 Ac-c~2Me 27:123,127 8-amino-8-deoxy-Neu5 Ac 27:121,122 8-azido-8-deoxy-Neu5Ac 27:121,122 8-tosyl-Neu5AcMe ester 27:121,122 9-amino-9-deoxy-Neu5 Ac 27:121,122 9-amino-9-deoxy-Neu5Ac-c~2Me 27:119 9-azido-9-deoxy-Neu5 Ac 27:121,22 9-azido-9-deoxy-Neu5Ac-c~2Me 27:119 9-O-acetyl-Neu5 Ac-(x2Me 27:119 9-tosyl-Neu5AcMe ester 27:121,122 Neu 5Ac methyl ester 27:120-122 Neu5Ac-cx2Me 27:119-121 Neu5Ac-ot2Me amide 27:119, 120 Neu5Ac-c~2Me benzyl ester 27:125-127 Neu5Ac-~2Me methyl ester 27:125-127 Neu5Ac-132Me methyl ester 3[3 27:125,127 peracetyl-Neu-c~2Me acid methyl ester 27:124,127 Haemagglutinin (HA) 27:103,107 for influenza infection 27:103 inhibitors of 27:117-129 Haemagglutinin-based inhibitors 16:111
1117 Haemolytic activity 23:512 of saikosaponins 23:512 Haemopoietic stem cells 30:766 Haemorrhagic fever virus (CCHFV) 30:410 Halichondride antitumor activity of 5:378,380 Haliclona sp. 5:346,347,459 Halicylindramide A 28:680 as antifungal substance 28:680 as cytotoxic substance 28:680 Halicylindramide B 28:680 as antifungal substance 28:680 as cytotoxic substance 28:680 Halicylindramide C 28:680 as antifungal substance 28:680 as cytotoxic substance 28:680 Halistanol disulfate B 28:699 in endothelin converting enzyme (ECE) assay 28:699 Halistanol sulfate 28:698 antimicrobial activity of 28:698 hemolytic activity of 28:698 ichthyotoxic activity of 28:698 pp60v-src protein tyrosine kinase inhibition activity 28:698 Halitunal antiviral activity of 16:302 Hallucinogenic agent 21:101 Halogen-containing antibiotics 29:309 biological effects of 29:309 chloramphenicol as 29:309 fluoroacetate as 29:310 4-fluorothreonine as 29:310 from Streptomyces venezuelae 29:309 from streptomycetes 29:309 (E)-13-Halogenoacrylamides 21:381 Halophilic bacteria 30:520 Hamster assay 21:671 Hamster fetus 23:570 encephalocele in 23:570 Harmaline 25:537 as immunosuppressive drug 25:537 Harmine 25:537 as immunosuppressive drag 25:537
Harpagide 29:83 activity in EBV assay system 29:83 Harzianic acid 28:135 antibiotic activity of 28:136 HBV 30:406 immunization against 30:406 HBV infection 20:528-530 HBV infectivity 30:406 H-Dmt-Tic-Ala-OH (DTA) 30:804 as 8-opioid receptor antagonist 30:804 Headache 30:192 use of non-steroidal antiinflammatory drugs (N S AIDs) 30:192 use of prostaglandin inhibitors 30:192 Healing properties 22:361 of 3',4-O-dimethylcedrusin 22:361 Heart diseases 30:55 role of natural products in 30:55 Heart rate 26:183 effect of Schisandra on 26:183 Heat-activated channel TRPVI 30:193 type of ionotropic receptor 30:193 Heat-inactivated proteases 25:439 Hederagenin 7:134,135,429,431-433, 9:61,62 molluscicidal activity of 7:432 Hederagenin (triterpene) 29:586 effects on LELA 29:586 Hederagenin monodesmosides 30.203, 204 agglutination inhibition by 30:204 anti-rheumatoidal effect of 30:204 edema inhibition by 30:204 effect on trypsin activity 30:204 trypsin production inhibition by 30:204 use in chronic rheumatoidal arthritis 30:204 vascular permeability inhibition by 30:204 HeLa 25:301 cells 25:268
1118
HeLa assay 25:45 HeLa cells inhibition 25:45,46 HeLa $3 Cells 25:790 Helenalin 29:90 activity in CRG assay system 29:90 activity in NFkB assay system 29:90 Helenalin acetate 29:90 activity in NFAT assay system 29:90 activity in NFkB assay system 29:90 Helenalin isobutyrate 29:90 activity in NFAT assay system 29:90 activity in NFkB assay system 29:90 Helenalin tigulinate 29:90 activity in NFAT assay system 29:90 activity in NFkB assay system 29:90 Helenanes 16:664 antiinflammatory activity of 16:664 antileukemic activity of 16:664 cyctotoxic activity of 16:664 Heliantriol C (taraxast-20-ene-3[3,16[3, 22cx-triol) 29:587 effects on CHY 29:587 Heliantriol C 3-O-myristate (taraxast20-ene-3 [3,1613,22c~-triol 3-0myristate) 29:587 effects on TRY 29:587 Helichrysum nitens 5:413 antifungal flavonoids from 5:651 Helicobacter pylori inhibition 30:338 by chrysophanol 30:338 by emodin 30:338 by rhein 30:338 Hemagglutinins 24:478-483,484 assay 24:483-480 fl-Hematin aggregation 25:342,354 inhibition of 25:342,354 Hematologic toxicity 27:436;28:559 with immunosuppression 28:559 with leukopenia 28:559
Hematopoietic cancer cells apoptosis 26:925 Hematoporetic stem cell 27:806 Heme aggregation 25:329,343,349,351, 352,353,355,356 Heme aggregation activity 25:341 Heme aggregation assays 25:348,352, 354 Heme aggregation efficacy 25:355 Heme aggregation inhibitor 25:327,329, 343,352,359 Heme detoxification 25:329,331 Heme polymerase 25:30,333 Heme polymerization 25:334,348 Heme polymerization assay 25:334,354 Heme polymerization inhibitor 25:327, 343,347,348 Heme polymerization inhibitory activity 25:345 Heme polymerizations 25:348 inhibition of 25:348 Heme proteolysis 25:331 Heme sequestration 25:348 inhibition of 25:384 fl-Hemetin 25:357 inhibitor of 25:357 fl-Hemetin aggregation 25:357 fl-Hemetin assay 25:355 Hemoglobin 30:59,60,65-67,69 carp oil effects on 30:66 effect of oleic acid on 30:65 effects of triterpenoid fractions on 59 oleic acid effects on 30:67 Hemoglobin proteolytic enzyme 25:360 Hemoglobin/HA interactions 26:985-987 Hemolysis 25:180,464 Hemolytic activity 21:660,661 ;26:41, 42;28:698 of Gypsophila paniculata 26:41 ofhalistanol sulfate 28:698 of SAPO 30 26:41 of SAPO 50 26:4I Hemorrhage complication 30:839 Hemorrhage-inducing activity 23:139 Hemostatic process 30:593 role ofplatelets in 30:593
1119 Hemozoin 25:354 inhibition of 25:354 Hemozoin aggregation 25:334,337 Hemozoin aggregation inhibition 25:342 Hemozoin inhibition 25:341,342,356 Hemozoin inhibitor drugs 25:360 Hemozoin nucleation 25:334 (Z)-Heneicos-6-en-11-one 19:124,126 sex pheromone of 19:124,126 Hep-2 (human carcinoma of larynx) 30:692 Heparanase activity 16:90 in malignant cells 16:90 Heparin 30:58,397,404 against pseudorabies virus 30:404 in HIV therapy 30:397 Heparin derivatives 30:399 anticoagulant activity of 30:399 Hepatic activity 26:253 Hepatic apoptosis 25:468 Hepatic DNA fragmentation 25:466, 467,468,469,472 Hepatic information 25:479 Hepatic intoxication 25:466 with D-Gal N 25:466 with LPS 25:466 Hepatic rnRNA induction 25:468 Hepatic total cholesterol concentration 30:93 effects of Platycodi radix on 30:93 Hepatic triacylglycerol 30:81,93 accumulation of 30:93 effect of high-fat diet on 30:93 Hepatitis 26:183;30:207 effect of Schisandra in 26:183 treatment of 30:207 use of Phyllanthus (genus) in 207 Hepatitis A virus 30:406 Hepatitis A,B,C 21:662 Hepatitis B capsid 30:406 Hepatitis B surface antigen 20:537 Hepatitis B virus 20:227,528;21:648, 656;25:114 Hepatitis D agent 30:406 Hepatitis-B surface antigen 30:840 bromelain 30:840
Hepatocarcinogenesis 26:257 Hepatocyte apoptosis 25:459,460,462, 464,468,469 Hepatocyte necrosis 25:466,468,476 Hepatocytes 23:14 Hepatoma cell 27:806 Hepatoma cell line PLC/PRF/5 30:406 Hepatopretective agent 22:358 ursolic acid as 22:358 Hepatoprotective 22:346 Achyrocline satureioides as 22:346 Hepatoprotective activity 20:116; 25:90,103,106,467,469,474 ;26:255, 257 ;28:257,293 ;30:291 ofbaicalein 30:291 ofbaicalin 30:291 of bupleuroside III,IV,XIII 25:474 of Curcumia longa L. 25:469 of ornithine glucuronides 25:90,103 ofpalustroside III 25:106 of plant polyphenols 28:257,293 of tetrahydroswertianolin (THS) 25:467 of wogonin 30:291 Hepatoprotective agent 22:346,358; 23:753;25:462,465 Achyrocline satureioides as 22:346 ursolic acid as 22:358 Hepatoprotective drugs 25:100,103 Hepatoprotective effect 25:100,106, 466,472 assay method for 25:100 of Colchicum autumnale 25:472 of glycyrrhizin 25:466 of oleanolic acid-type glucuronide saponins 25:106 of plants 25:459 of sinomenine 25:472,476 Hepatoprotective mechanism 25:472 of coumarins 25:472 Hepatoprotective natural products 25:465 Hepatoprotective phytoconstituents 25:477 Hepatoprotective proteins 25:461
1120
Hepatoprotective saponin 25:465 Hepatosplenomegaly 26:785 Hepatotoxcity 21:651,654 Hepatotoxic cyclic peptides of cyanobacterial origin 20:887-913 Hepatotoxic principle 27:879 of Anabaena genera 27:879 of Microcystis genera 27:879 of Oscillatoria genera 27:879 Hepatotoxicity 22:8;25:461,471 cyanobacterial 9:496-499 Herbal antidepressant 30:333 Hypericum perforatum as 30:333 Herbal drugs 25:44 as antitumor-promotor 25:44 Herbal formulation AV/EPP/14 28:401 against larvae 28:402 against nymphs of Boophilus microplus 28:402 Herbal medicines 24:261 activities of 24:261 Herbasterol 5:410 antimicrobial activity of 5:410 ichtyotoxic activity of 5:410 Herbicidal 24:799,867 bioassay of 24:867 biological activity 24:799 Herbicidal activity 21:435;23:73;24:819 against dicotyledonous plants 23:73 against monocotyledonous plants 23:73 of Piqueria trinervia 24:779, 817-819 Herbicidal antibiotic 5:592,607 Herbicides 7:398,383,384,387 Herbimycin 5:592 as an antitumor antibiotic 5:592 as herbicidal agent 5:592 (+)-Hernandaline 30:563,594 as platelet aggregation inhibitor 30:594 Hernandia 30:559-561,563-580 biological studies of 30:561 Hernandia moerenhoutiana 30.'561,597 antimalarial activity of 30:561 antioxidant activity of 30:561 biological activities of 30:562
cytotoxic activity of 30:561 spasmolytic activity of 30:561 to retain placenta 30:561 to treat malaria 30:561 use in morning sickness 30:561 use in postpartum hemorrhage 30:561 use in treament of malaria 30:597 use in treament of morning sickness 30:597 use in treament of postpartum hemorrhage 30:597 Hernandia nymphaeifolia 30:561,563570,597 biological activities of 30:562 to retain placenta 30:561 to treat malaria 30:561,597 use in morning sickness 30:561 use in postpartum hemorrhage 30:561,597 Hernandia sp. 30:561,562,588,589, 594,597 activity in antiplatelet aggregation turbidimetry assay 30:594 activity in human murine cancer cell line 30:589 activity in human tumor xenograft system 30:589 activity in mouse model 30:589 antimalarial activities of 30:588 antioxidant activity of 30:597 antiplatelet aggregation activity of 30:588 anti-tumor activity of 30:589 biological activities of 30:562 cancer chemopreventive activity of 30:588 cytotoxic activity of 30:588,589, 597 inhibitory effects of 30:594 role in morning sickness 30:561 role in placenta 30:561 role in postpartum hemorrhage 30:561 spasmodic activity of 30:597 Hernandia voyronii 30:561,562,564566,569,597
1121
antimalarial activity of 30:561 antioxidant activity of 30:561 biological activities of 30:562 spasmolytic activity of 30:561 to retain placenta 30:561 to treat malaria 30:561 use in morning sickness 30:561 use in postpartum hemorrhage 30:561 use in treament of malaria 30:597 use in treament of morning sickness 30:597 use in treament of postpartum hemorrhage 30:597 Hernandonine 30:564,589 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:589 Herniaria fontanesii 26:52,54 litholytic properties of 26:52,54 Herniaria hirsuta 26:50 in arrthritis 26:50 in infections of urinary tract 26:50 in infections of respiratory tract 26:50 in kidney disorders 26:50 in neural catarrh 26:50 in neuritis 26:50 in purifying blood 26:50 in rheumatism 26:50 (-)-Hernone 26:212;30:569,587,590,595 activity in human cancer cell lines 30:589 as platelet aggregation inhibitor 30:594 cytotoxicity of 26:212 cytotoxic effect of 30:589 (+)-Hernovine 30:564,589 cytotoxic effect of 30:589 Heroin 18:48 Herpes infection 30:400,401 role of vericella-zoster virus in 30:400 Herpes simplex virus 26:223;30:394, 395,400,412
cause of 30:394 inhibitor of 30:395 type 1 (HSV-1) 30:394,400 virus type II (HSV-2) 30:394, 400 Herpes simplex virus type 1 (HSV-1) 30:743,752 antiviral activity 30:743 Herpes simplex virus type II 30:752 Herpesviridae family 30:401 infections caused by 30:401 Hervelines A-C 30:596 antiplasmodial activity of 30:596 Hervelines A-D 30:595,596 antimalarial activity of 30:595 antiplasmodial activity of 30:596 Hesperidin (3 ',5,7-trihydroxy-4'methoxyflavanone-7-rutinoside) 29:579 effects on ACE 29:579 Heterophyllin 28:230 biological activity of 28:230 12-O-Hexadecanoyl- 16-hydroxyphorbol- 13-acetate (HHPA) 25:45 induced edema inhibition (HPA) 25:46 9-nor-9-OH-Hexahydrocannobinol (HHC) 30:195,196 analgesic activity of 30:195 structure of 30:197 Hexaprenyl-hydroquinone sulfate 28:676 as H+/K+-ATPase inhibitor 28:676 HHPA 25:55 inhibitory effects on 25:55 HHPA induced edema (HPA) 25:45 HHPA-induced inflammation 25:56 Hibiscus abelmoschus L. 22:522 for hysteria 22:522 High-fat diet-induced model 30:80 of obesity 30:80 High-fat diet-induced obesity 30:82 prevention of 30:80,82 Himax 28:416 acaricidal action of 28:416 against demodectic mites 28:416
1122
against psoroptic mites 28:416 against sarcoptic mites 28:416 Hinokiol 29:101 activity in CRG bioassay system 29:101 Hippocampal neurons 22:26;30:376 in infantile autism 30:376 morphology of 30:376 HIRE 24:951-954 antibiotic activity of 24:953-954 bioactive compounds from 24:951-954 bioactivity of 24:951-954 His2t5 family inhibitors 26:368 Hispaglabridin A 28:228 biological activity of 28:228 Histamine 30:192 as pain mediator 30:192 from vessels 30:192 Histamine induced edema 25:46 Histamine production 25:611 Histamine receptor 25:611,34 Histamine release 25:47 inhibition of 25:47 Histamine release inhibition 23:357; 24:914-917 by coumarine 23:357 by oosponal 24:914-917 o f M o r u s spp. 24:914-917 Histamine release inhibitor 28:257,293 polyphenols as 28:257,293 Histamine secretion 25:936 Histamine/peptide leukotriene C4 (LCT4) 25:275 Histamine-induced hind paw edema 26:401 Histidine 25:334,335,526,813 Histological examination 27:310 of consuming stevioside effects 27:310 of reproduction tissue 27:310 Histrionicotoxins 21:70,73 Hitachi high throughput purification (HTP) 29:651 via chromatography system 29:654 COX-1 inhibition profile by 29:657
for mushroom tyrosinase inhibition 29:656 HIV (human immuno deficiency virus) 7:12 HIV- assay 19:757 HIV enzymes 30:397 HIV reverse transcriptase 30:397 HIV integrase 30:397 HIV inhibitory effects 23:706 ofbetulinic acid 23:706 HIV infection treatment 30:396 role of carbohydrates in 30:396 role of sulphated polysaccharide (PS) in 30:396 HIV infections 30:396 chemotherapy of 30:396 HIV inhibition 23:704 by salaspermic acid 23:704 HIV inhibitor 30:399 in vitro 30:399 HIV inhibitory activity of 28:121 of equisetin 28:121 HIV integrase (IN) 25:941,942;30:226 against AIDS 30:226 mechanism of action 30:226 HIV protease 30:397 role in integration 30:397 HIV replication cycle 30:226 role ifintegrase in 30:226 role ofprotease in 30:226 role of reverse transcriptase in 30:226 HIV therapy 30:397 dextran sulphate in 30:397 pentosan sulphate in 30:397 chondroitin sulphate in 30:397 heparin in 30:397 HIV whole cell assay 19:757 HIV-1 22:675;30:397 inhibitor of 30:397 in vitro 30:397 HIV-1 IN inhibitor 30:228 trifluoromethyl pharmacophore as 30:228 HIV-1 infected H9 cells 30:226 lithospermic acids effect on 30:226 HIV-1 infection 30:399 inhibitory effects on 30:399
1123
HIV-1 integrase 30:226 effect of natural polyphenols on 30:226 HIV-1 integrase inhibition 30:226 in vitro 30:226 HIV- 1 integrase inhibitors 30:218,227 lithospermic acid A type of 30:227 lithospermic acid B type of 30:227 HIV-1 p24 antigen 30:396 inhibitor of 30:396 HIV-1 protease 29:574 absinthin (guaine sesquiterpene dimer) effects on 29:574 absintholide (guaine sesquiterpene dimer) effects on 29:574 HIV-1 protease inhibitor 24:489 indinavir as 24:489 HIV- 1 reverse transcriptase (RT) 28:702 clathsterol against 28:702 HIV- 1 RT inhibition by anolignan A&B 26:224 HIV-protease 25:941,942 HIV-protease inhibitor 24:489 ritonavir as 24:489 saquinavir as 24:489 HIV-reverse transcriptase inhibitor 30:412,400 HK-mediated neurotoxicity 26:992 HL-60 cells 22:616,617 HL-60 leukemia cell 21:637 HMGR 24:373-376 role of cholesterol oxides 24:351-398 HMPT 26:1091,1092 antimicrobial activity of 26:1091,1092 HMR1826 21:176,177 preclinical development of 21:176 HMTP 26:1099 antimicrobial activity of 26:1099 Hodgkin's disease 4:29;22:343 vinblastine for 14:805 vincristine for 14:805 Hodgkinsin 30:205 antinociceptive activity of
30:205 in pin model 30:205 in thermal model 30:205 Honokiol 26:217;240 inhibitory activity of 26:217 as PAF-induced inhibitor 26:240 Honokiol (lignan) 29:582 effects on MMP 29:582 Hordeum lipid transfer proteins 29:593 effects on barley malt cysteine endoproteinases 29:593 Hormone-activated guanylate cyclase (GC) 25:519 Hormone-activated receptor tyrosine kinase 25:518 Hormones 18:819-866;19:627-687 bioactive conformations of 18:819-866 Host microorganism selectivity 23:42 Host-mediated activity 25:431 of Chlorella vulgaris strain CK 22 (CVs) 25:431 Host-mediated antitumor activity 23:445 of tannic acid 23:445 Host-mediated immunomodulator 30:768 CVE as 30:768 Host-splenomegaly response 30:4 inhibition by (+)-discodermolide 30:4 Hot plate test 30:207,802,804,581 activity of (-)-menthol in 30:207 for determination of antinociception 30:802 ofpeptide 30:804 House dust 24:914-917 contraction with tachyphylaxis 24:914-917 House dust mites 28:417 Actinodaphne lancifolia against 28:419 benzyl benzoate against 28:418 Cinnamomum camphora against 28:419 Cinnamomum japonicum against 28:419
Dermatophagoides farinae
1124
against 28:417 Dermatophagoides pteronyssinus against 28:417 Euroglyphus maynei against 28:417 Lindera umbellata against 28:419 Melaleuca acacoides against 28:419 Melaleuca symphycarpa against 28:419 Neolitsea sericea against 28:419 Persia thunbergii against 28:419 Taiwania cryptomerioides against 28:418 tannic acid against 28:418 treatment of 28:418 HRP II inhibition 25:336 HRP II mediated hemozoin synthesis assays 25:352 HRV inhibitors 30:407 in vitro 30:407 from Stevia rebaudiana 30:407 HRV replication inhibitor 30:407 in vitro 30:407 mechanism of 30:407 HSV infections 30:401 acyclovir-resistance in 30:401 antiviral medications for 30:401 symptoms of 30:401 HSV-1 24:524 activity of actinoplanic acids against 24:524 HSV-1 30:402,403 antiviral activity against 30:403 in vivo 30:403 inhibitor of 30:402 HSV- 1 corneal infection therapeutic efficacy against 21:697 HSV-1 infection 21:694 HSV-1 replication 21:695 inhibitory effect on 21:695 HSV- 1 replication inhibitory effect on 21:695 HSV-2 30:402,403 in vitro 30:402 inhibitors of 30:402
HSV-2-virus antiviral activity against 4:237 Co-3-human colon carcinoma 19:289 HT-29 (human colon carcinoma) 30:588,691 activity of (-)-deoxypodophyllotoxin against 30:588 activity of (-)-yatein against 30:588 phenolic triterpenes against 30:691 HT3 class receptors 25:529 5 5-HT3 receptor 27:286 5-HT4 receptor 27:286 Human breast cancer cell line MCF-7 30:314 human cancer cell lines 30:589,590 activity of (-)-deoxypodophyllotoxin in 30:589 activity of (-)-hemone in 30:590 activity of (-)-nymphone in 30:590 activity of (-)-yatein in 30:590 activity of (+)-corytuberine in 30:589 activity of (+)-epiaschantin in 30:590 activity of (+)-epimagnolin in 30:590 activity of (+)-epiyangambin in 30:590 activity of (+)-hernovine in 30:589 activity of (+)-laurotetanine in 30:589 activity of (+)-magnoflorine in 30:589 activity of (+)-malekulatine in 30:590 activity of (+)-N- activity of hydroxyhernangerine in 30:589 activity of (+)-N- formylnornantenine in 30:589 activity of (+)-N-formyldehydroovigerine in 30:589 activity of (+)-N-formylovigerine in 30:589
1125 activity of (+)-ovigerine in 30:590 activity of (+)-ovihernangerine in 30:590 activity of (+)-vateamine-2'13-Noxide in 30:590 activity of 7-formyldehydrohernangerine in 30:589 activity of 7-formyldehydronornantenine in 30:589 activity of 7-formyldehydroovigerine in 30:589 activity of 7-hydroxy-6-methoxy1-methylisoquinoline in 30:589 activity of 7-oxohernagine in 30:590 activity of demethylsonodione in 30:589 activity of hernandonine in 30:589 activity of hernanymphine in 30:589 activity of N-hydroxyovigerine in 30:589 activity of N-methylcorydaldine in 30:589 activity of N-methylovigerine in 30:590 activity of thalifoline in 30:590 Human carcinoma 24:6 of nasopharynx (KB) 24:6 Human chemopreventives 30:592 Human colon adenocarcinoma cell cultures 25:903 Human colon carcinoma 23:255,290 Human cytomegalovirus 30:395 inhibitor of 30:395 Human cytomegalovirus (HCMV) 21:646 Human cytomegalovirus protease inhibitors 28:118 bripiodionen as 28:117,118 Human diseases 30:224 aging 30:224 atherosclerosis 30:224 cancer 30:224 cardiac diseases 30:224 diabetes inflammation 30:224 intestinal diseases 30:224
neurodegeneration 30:224 reperfusion injuries 30:224 respiratory disorders 30:224 role of free radicals in 30:224 Human growth hormone 4:271 Human HEK 293 cell line 30:781 biological response of 30:781 Human HL-60 leukemia cells 30:496 differentiation of 30:496 inhibition of 30:496 proliferation of 30:496 Human immunodeficiency virus 7:12, 396;21:149;26:223 ;30:226,395,396, 412 inhibitor of 30:395 Human immunodeficiency virus type-1 25:948 Human interleukin-[3 21:404 Human leucocyte elastase 25:47 inhibition of 25:47 Human leukemia cells 18:269 Human leukocyte elastase 16:727 inhibitor of 16:727 Human leukocyte elastase (HLE) 30:830,831,843 homologous sequences of 30:831 plasminogen activator (u-PA) 30:830 Human lung carcinoma 23:290;30:5 discodermolide against 3 0 : 5 A-549 (Human lung carcinoma) 30:691 phenolic triterpenes against 30:691 Human medulloblastoma 23:290 Human melanoma 23:255 Human mesangial cell proliferation 30:308 in vitro 30:308 Human monoblastic leukemia cells 30:498 effect of hydroxyurea (HU) 30:498 growth inhibition of 30:498 Human monoblastic leukemia U937 cells 30:498 growth inhibition of 30:498
1126
Human nasopharyngeal KB staurosporine activity against 12:390 Human neuroblastoma NB-1 cells cytotoxic against staurosporine 12:390 Human neuroblastoma nbla-N-5 cells tamoxifen activity against 12:390 Human neuroblastoma SH-SY-5Y cells 12:390 Human neutrophils 12:390 Human neutropil protein kinase C 12:389 Human onchocerciasis 12:9 ivermectin for 12:9 Human papilloma virus 30:394 pathogenesis of 30:394 cause of hepatocellular carcinoma 30:394 Human Papilloma virus (HPV) 23:97; 26:223 Human papilloma virus type 11 30:406 microbicidal compound against 30:406 Human papilloma virus type 40 30:406 microbicidal compound against 30:406 Human platelets 12:390 study of protein kinase C in 12:390 by staurosporine 12:390 Human rotavirus (HRV) 30:406,412 cause of dehydrating gastroenteritis 30:406 member of 30:406 reoviridae type of 30:406 Human serotonin transporter gene (SLC6A4) 30:376 regulation of neuronal activity 30:376 Human spermatozoa motility 21:675 Human synovial PLA2 25:697 inhibitor of 25:697 Human xenografted carcinomas 19:330 Humulones 24:902-904 anti-glycemic effects 24:902-904 anti-hyperglycemic effects of 24:902-904
Hup A 21:748-750 clinical trials of 21:750 Hv-CPI phytocystatin 29:593 effects on chymopapain 29:593 effects on ficin papain 29:593 Hyalurnidase-inhibitory activity 25:939 Hydrocholeretic effect 26:391,399,415 Hydrocortisone 25:56,57 Hydrolysable tannins 27:840 activity of 27:840 Hydroperoxides cyctotoxic activity of 5:409 15-(2-Hydroxy)-isobutyryloxy-micrantholide 29:89 activity in TNFcz assay system 29:89 14-Hydroxy- 15-isovaleroyloxy-9-oxomelampolide 29:89 activity in NFkB assay system 29:89 3-Hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase 24:351-398 fungal metabolism of 24:361,362 in metabolism 24:359-361 regulation of 24:361,362
12-Hydroxy-6,7-seco-abieta-8,11,13-
trien-6,7-dial 29:99 activity in EBV assay system 29:99 7-Hydroxy-6-methoxy- 1-methylisoquinoline 30:564,589 activity in human cancer cell line 30:589 cytotoxic effect of 30:589 9ct-Hydroxy-8 [3-methacryloyloxy- 14oxo-acanthopsermolide-4c~, 5 [3epoxide 29:89 activity in NFkB assay system 29:89 8D-Hydroxy-9c~-methacryloyloxy- 14oxo-acanthospermolide 29:89 activity in NFkB assay system 29:89 from Milleria quiqueflora 29:89 Hydroxyachillin 29:89 activity in TPA assay system
1127 29:89 activity in PKC assay system 29:89 activity in CRG assay system 29:89 25-Hydroxycholesterol 24:352 cytotoxicity effect of 24:352 7-Hydroxycostunolide 29:89 activity in NFkB assay system 29:89 3-Hydroxycoumarin 30:220,221,225 antioxidant properties of 30:225 Hydroxycoumarins 26:330 antimicrobial activity of 26:330 12-Hydroxydehydroabietic acid 29:99 activity in EBV assay system 29:99 4-Hydroxyderricin 30:74,76 effect on catecholamine-induced vasoconstriction 30:74 inhibitory action of 30:76 inhibitory mechanism of 30:74 10-Hydroxyellipticine 6:507 anticancer activity of 6:507 3-Hydroxyglabrol 28:228 biological activity of 28:228 (+)-N-Hydroxyhernangerine 30:564,589 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:589 14-Hydroxyhypocretenolide 29:90 activity in NFkB assay system 29:90 activity in CRO assay system 29:90 14-Hydroxyhypocretenolide-[3-Dglucoside-4',4"-hydroxy-hypocretenoate 29:90 activity in CRO assay system 29:90 activity in iNOS assay system 29:90 activity in NFkB assay system 29:90 17-Hydroxy-ingenol 20-hexadecanoate 29:102
activity in mam-2 bioassay system 29:102 12S-Hydroxylabda- 8(17), 13(16), 14trien- 19-oic acid 29:101 activity in EBV bioassay system 29:101 e n t - 15-Hydroxy-labda-8(17), 13E-dien3-one 29:102 activity in EBV bioassay system 29:102 l~-Hydroxylase 9:515 inhibitors of 9:515 14a-Hydroxy-MFA 28:340 biological activity of 28:340 Hydroxynagilactone F 28:4752anti-fungal activity of 28:475 Hydroxynaphthoquinone metal complexes 30:314 as antitumor agent 30:314 8-Hydroxy-naringenin 28:64 antioxidant activity of 28:64 N-Hydroxyovigerine 30:564,589 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:589 3-Hydroxyparatocharpin C g 28:228 biological activity of 28:228 15-c~-Hydroxypristimerin 30:665,692 against HeLa (human carcinoma of cervix) 30:692 cytotoxic activity of 30:692 6c~-Hydroxysugiol 29:99 activity in EBV assay system 29:99 Hydroxy-tingenone 30:696 effect on feeding activity 30:696 effect on larvae development 30:696 effect on mortality 30:696 20c~-Hydroxy-tingenone 30:696 assay of 30:696 6~-Hydroxyvouacapan- 17,7 [~-lactone 29:103 activity in AOS bioassay system 29:103
1128
(-)-6'-Hydroxyyatein 26:212 cytotoxicity of 26:212 8-Hydroxy-c~-humulene 29:91 activity in EBV assay system 29:91 Hylauronidase 25:47 inhibition of 25:47 Hymenin 29:91 activity in TPA assay system 29:91 Hyoscyamus niger 22:523 for epilepsy 22:523 Hypaconite 24:898-899 neuromuscular blocking effect 24:898-899 Hypaconitine 24:898-900 in neuromuscular blocking effect 24:898,899 Hypercalcemic activity 30:497 of 24-epi-la,25(OH)2D2 30:497 of la,25(OH)2D7 30:497 Hypercholesterolemia 21:212,669; 22:250,252 Hypercytokinemia 25:463 Hyperforin 30:611,627,628 against Bacillus cereus 30:628 against Bacillus subtilis 30:628 against gram-positive bacteria 30:628 against Staphyllococcus aureus 30:628 effect on re-uptake of neurotransmitters 30:627 Hyperforin inhibitors 30:627 in depression 30:627 serotonin as 30:627 dopamine as 30:627 noradrenaline as 30:627 GABA as 30:627 Hypericin 30:345,607,608,624,626-628 against herpes simplex virus types I and II 30:627 against retrovirus 30:627 against vesicular stomatitis 30:627 as antibiotic from 30:628 as inhibitor 30:626 as inhibitor of virus replication
30:628 as photoreceptor 30:607 as virucidal agents 30:627 in vivo virucidal efficacy 30:628 mechanism of action of 30:626 minimum inhibitory concentrations (MIC) 30:628 retroviral activity of 7:421 use for mild depression 30:345 use for moderate depression 30:345 virucidal effect of 30:627 Hypericum ascyron 30:620 in treatment of abscesses 30:620 in treatment of headache 30:620 in treatment of nausea 30:620 Hypericum brasiliense 30:611,629 against Bacillus subtilis 30:629 Hypericum compound H8 (prenylated xanthone) 29:579,581 effects on ACE 29:579 effects on NEP 29:581 Hypericum extracts 30:626 in vitro 30:626 inhibitor of dopamine 30:626 inhibitor ofnoradrenaline 30:626 inhibitor of monoamine neurotransmitters 30:626 inhibitor ofserotonin 30:626 Hypericum genus 30:603 bioactivity of 30:603 Hypericumjaponicum 30:611,614,629 antimicrobial activity of 30:629 as herbal drug 30:614 for gastrointestinal disorders 30:614 for hepatitis 30:614 in diseases 30:614 in treatment of bacterial infections 30:614 prenylated phloroglucinols from 30:611 Hypericum mysorense 30:629 against Bacillus coagulans 30:629 against Bacillus megatorium 30:629 against Bacillus subtilis 30:629 against gram-positive organisms
1129
30:629 against Staphylococcus aureus 30:629 Hypericum papuanum 30:616 in treatment of sores 30:616 Hypericum patulum 30:619,622,629 against Eisenia coli bacteria 30:629 against Pseudomonas cepacia 30:629 flavonoids from 30:619 Hypericum perforatum 30:407,603,604, 605,609,610,616,618,619,622,624, 626-629 against infected wounds 30:628 against skin lesions 30:628 antimicrobial activity of 30:628 antiviral activity of 30:407,627 in treatment abdominal pain 30:603 in treatment of isoquercitrin from 30:618 in treatment of melancholia 30:603 in treatment of ulcerated bums 30:603 in treatment of urogenital pain 30:603 in depression treatment 30:624, 629 mechanism of action of 30:624 pharmacology of 30:624 Hypericum sampsonii 30:622 against diarrhoea 30:622 against snake bites 30:622 against swellings 30:622 Hyperkinetic ventricular arrhythmias 25:594 Hyperlipemia 22:607,608 Hyperlipidaemia 27:405;30:55,56,58, 70,83,88,98,101 biological activity of 27:405 due to high-fat diet 30:98 in mice 30:101 prevention of 30:56 role of natural products in 30:55 treatment of 30:56 use of Ganoderman lucidum in 30:58
use of Laminaria japonica Aresch 30:in 56 use of orlistat (Ro 18-0647) in 30:83 use of Platycodi radix 30:88 Hyperplasia 30:375 of cerebral grey matter 30:375 of cerebellae white matter 30:375 Hypersensitive response 25:394,402; 27:61 Hyperserotonemia 30:381,368 in autism 30:381 Hypertension 30:55,58,72,201,368 role of Angelica keiskei in 30:72 role of Ganoderman lucidum in 30:58 role of natural products in 30:55 role of serotonin (5-HT) in 30:368 Hypocholesterdemic effects 25:222 ofsoyabean saponins 25:222,223 Hypocholesterolemic agent 13:554; 21:616; 26:246 Hypocholesterolemic atherosclerosis 26:248,249 Hypocholesterolemic drug 5:195 Hypocholesterolemic effect 26:44,54, 205 of Gypsophila capitala 26:44 Hypocholesterolic effects 26:233 Hypoglycaemic effect 30:80,94,294 of Ajuga iva (L.) 30:294 of saponon 30:94 of tea saponin 30:80 Hypoglycemic activity 18:672;21:460, 488,666;26:398 Hypoglycemic agent 21:459,488 phytochemicals as 21:457 Hypoglycemic effects 17:139 Hypolipidaemic effects 27:400 Hypolipidemic action 26:887 Hypolipidemic activity 23:357;26:247 of scoparone 23:357 Hypotensive action 28:200,209,207; 30:787 of isoprenylated flavonoids 28:207 ofkuwanon G 28:209
1130 ofkuwanon H 28:200,209 mechanism of 30:787 ofMorus alba 28:200 of Morus species 28:207 of mulberrofuran C 28:209 of mulberrofuran F 28:209 of mulberrofuran G 28:209 Hypotensive activities 17:451 21:690; 27:481 of Astragalus membranaceus roots 27:481,483 of cryptolepine 5:752 Hypotensive alkaloid 5:751,752 Hypothalamic neuropeptide 27:794 Hypothalamus-pituitary 27:794 Hypothermal activity 23:353 of Coumarin 23:335,356,357, 353,368,376,393,550,553 Hypothermia 30:194 due to opioids 30:194 Hypothermic activity 23:800 Hypothyroidism 30:374 autistic features in 30:374 Hypotriglyceridemic effect 26:246,261 Hyrtiomanzamine 28:691 immunosuppressive activity of 28:691 Hysteria 22:510,512,513,516,518,519, 521,522,525-529,531,534 Achyranthes aspera L for 22:510 Acorus calamus L. in 22:510 Anagallis arvensis L. for 22:512 Asarum maranthuym Hook. For 22:513 Cinnamomum camphora for 22:516 Cynodon dactylon L. for 22:516 Cynodon dactylon L. Pers. For 22:518 Dictamnus albus L. 22:519,521 Ferula alliacea for 22:521 Flemingia strobilifera for 22:521 Galium verum L. for 22:521 Hibiscus abelmoschus L. for 22:522 Linum usitatissimum L. for 22:525 Lobelia inflata L. for 22:525
Martynia chamomilla L. for 22:526
Matricaria aurea L. for 22:526 Melissa offlcinalis L. for 22:526 Moringa oleifera for 22:526 Musa paradisiaca L. for 22:526 Nordostachys jatamansi DC. For 22.527 Olacaceae for 22:720 Paeonia emodi for 22:528 Paeonia officinalis L. for 22:528,529 Peganum harmala L. for 22:529 Ruta graveolens L. for 22:531 Sapindus trifoliatus L. for 22:531 Valeriana hardwickii for 22:534 Valeriana officinalis L. for 22:534 Valeriana wallichii for 22:534 Hysterin 29:90 activity in TPA assay system 29:90 Hystero-epilepsy 22:513,525,527,528, 531,532,534 Benincasa hispida use for 22:513 Mangifera odorata L. for 22:525 Nardostachysjatamansi DC. For 22:527 Nardostachysjatamansi DC. For 22:527 Paeonia emodi for 22:528 Sapindus trifoliatus L. for 22:531 Semecarpus anacardium L. for 22:532 Valeriana hardwickii for 22:534 Valeriana officinalis L. for 22:534 Valeriana wallichii for 22:534
Ianchinenoside E 26:38 c-AMP phosphodiesterase inhibitory activity of 26:38 Ianthella basta 28:695 as Ca2+-channel agonists 28:695
1131 Iantheran A 28:695 as Na+/K+-ATPase inhibitor 28:695 Ibisterol sulfate 28:700 against HIV-1 28:700 Ibogaine 25:533,537 as immunosuppressive drug 25:533,537 Ibogamine 25:533,537 as immunosuppressive drug 25:533,537 Ibuprofen 30:192 as cyclooxygenase enzyme (COX) inhibitor 30:192 ICAM-1 expression 30:70,71 inhibitory effect on 30:70,71 Ichthyotoxic activity 28:698 ofhalistanol sulfate 28:698 Ichthyotoxic agent 21:267,275,365 Ichthyotoxicity 17:24;18:607,716 Ichthytoxic activity 25:768;26:485 Ichtyotoxic agent 25:730 IFN-T 25:465 IG isotypes 24:168-170 IgE production 30:773 inhibition of 30:773 against casein 30:773 IgGl-antibodies 21:646 IgG2a-antibodies 21:646 Ikarugamycin 28:138,140 anti-bacterial activity of 28:140 antiprotozoal activity of 28:138 IL- 1c~ 30:689,771 inhibitory activity of 30:689 IL-l[3 30:689 inhibitory activity of 30:689 IL-2 production 30:782 by macrophages/dendritic cells 30:782 by TLR2 signaling 30:782 Ilicic acid 29:87 activity in TPA, AA, EPP assay systems 29:87 Ilimaquinone 5:430;15:291,314 antimicrobial activity of 5:434, 437 Imanine 30:628 antibacterial properties of 30:628
Imidazolone 5:412 cytotoxic activity of 5:413,415 Imipenem 4:432 antibiotic potency of 4:432 PBP-2 affinity for 4:433 Immune disorders 30:484 use of lo;,25(OH)2D3 30:484 Immune response 30:766,770 against Listeria monocytogenes 30:770 by ~[3 T cells 30:766 Immune-active acidic glycoprotein 25:455 from Chlorellavulgaris 25:455 Immune-mediated cytotoxicity 21:656; 25:467 Immune-suppression mycosis 22:56 Immunization 30:408 against measles 30:408 Immuno deficiency virus (HIV) 22:646, 648 Immunoadjuvant saponins 21:646 Immunoadjuvants 21:646 saponins as 21:646 Immunoblotting 25:499 Immunocompetent organ toxicity 28:561 chitosan inhibitory effect on 28:561 Immunocompetent organic toxicity 27:436;28:560 of5-fluorouracil (5-FU) 28:560 Immunodeficiency syndrome 30:226, 394 causative agent of 30:394 Immuno-deficiency virus 25:734; 30:397 use of HIV-1 30:397 use of HIV-2 30:397 Immunodulatory activity 30:395 ofpolysaccharide (PS) 30:395 Immunoglobulin G 22:374;30:837 F-II hydrolysis of 30:837 Immunoglobulins 24:140-144 Immunohistopathology 26:792 Immunological activity 23:107 of fungal ~-glucans 23:107
1132
Immunological role 30:422 of 3-deoxyulosonic acids 30:422 stereocontrolled chemical syntheses in 30:422 Immunomodulating action 24:131, 149-152 Immunomodulating activity 23:129 of fungal [3-glucans 23:129 Immunomodulator activity 23:687 Immunomodulatory actions 26:1036 Immunomodulatory activity 21:316,645 Immuno-modulatory effect 21:134; 26:31,50,55 of Acanthophyllum squarrosum 26:55 of Gypsophila saponins 26:55 of squarroside A 26:31 of Vaccaria segetalis 26:50 Immunopathological reactions 26:787 Immunopharmacology 30:766 of Chlorella 30:766 of green algae 766 Immunopotentiating effects 25:429 of Chlorella vulgaris strain CK 22 (CVs) 25:429 Immunoprecipitated CDK2 kinase 21:136 Immunostimulant effect 27:513 of polysaccharide 27:513 of Astragalus membranaceus 27:513 Immunostimulant saponins 21:646 Immunostimulants 21:651 saponins as 21:651 Immunostimulating action 24:131, 144-148,153,171 Immunostimulating complexes 21:648 Immunostimulating saponins 24:131-171 Immunosuppressant agents 16:561 Immunosuppressants 22:248 Immunosuppressive activity 18:739, 921 ;23:522,649,681 ;26:214,482 ofdidemnins 10:257,258 of diterpene triepoxides 23:649 of euonine 23:681 of evonine 23:681 of sesquiterpene pyridine alkaloids 23:649
of verbascoside 23:522 of wilfortine 23:681 of ~-apopicoropodophyllin 26:214 Immunosuppressive agent 30:3 discodermolide as 30:3 pironetin as 30:3 Immunosuppressive disease 30:396 Immunosuppressive drugs 21:661; 25:464 FK 508 as 25:464 dexamethasone as 25:464 amphetamine as 25:537 calebassine as 25:528 carcurine as 25:528 coronaridine as 25:533 eseramine as 25:536 eseridine as 25:536 harmaline as 25:537 harmine as 25:537 ibogaine as 25:533,537 ibogamine as 25:533,537 physostigmine as 25:536 physovenine as 25:536 reserpine as 25:538 sapargine as 25:528 strychnine as 25:530 tabernanthine as 25:533 toxiferine as 25:528 yohimbine as 25:530 Immunosuppressive effect 26:486;30:26 on blastogenesis 30:27 of pironetin 30:26 Immunosuppressive therapy 20:528 Immunosupressive agents 22:257 Immunotherapy 28:543 detox for 28:543 Immunotoxicity 28:562;30:56 by doxorubicin 28:562 due to cancer drug chemotherapy 30:56 Immunstimulatory activity 26:797 In vitro 30:59,61,396,594,596,810,815 antiplasmodial activity of 30:596 antiplasmodial activity of chloroquine 30:596 antiplatelet aggregation turbidimetry assay 30:594 DNA synthesis 30:61
1133 glycopeptides 30:815 HIV replication 30:396 Lewis lung carcinoma 30:59 receptor binding assay 30:810 In vitro activities 28:470,467;30:816 of glycopeptides 30:816 of milanjilactone A 28:470 of milanjilactone B 28:470 ofnagilactone G 28:470 ofnagilactone F 28:470 ofpodolactones 28:467 In vitro bioassay 30:591 for chemopreventive activity 30:591 In vitro studies 30:61,195,203,593,597, 805,815 of anandamide 30:195 of angiogenesis 30:61 of antinociception 30:805 of chloroquine potentiating antiplasmodial activity 30:597 of ginseng extract 30:203 of ginsenosides 30:203 of glyco analogues activity 30:817 ofherveline A 30:597 of mouse fail-flick assay 30:815 ofparasitemia inhibitor 30:597 of tetrahydrocannabinol (THC) 30:195 of tumor-promotion 30:593 In vivo testing 24:491 of anti-viral agent 24:491 Inactivation pathway 27:321,345 of ABA 27:345 Incarvillateine 30:204 as antinociceptive agent 30:205 from Incarvillea sinensis 30:204 inflammatory pain inhibition by 30:205 neurogenic pain inhibition by 205 Indinavir 24:489 inhibitor of HIV- 1 protease 24:489 Indirect immunofluorescence 24:217 bis-Indolyl maleimides 12:365,372, 375-383 biological activity of 12:384-399 protein kinase activity of 12:389
Indomethacin 27:689,690;30:192 as cyclooxygenase enzyme (COX) inhibitor 30' 192 Indo-pacific marine invertebrates 21:251 bioactive metabolites from 21:251 Induced skin tumor 29:76 by DMBA/fumonsin-B1 29:76 t,y DMBA/mineral oil 29:76 by DMBA/okadaic acid 29:76 by DMBA/teleocidin B 29:76 by DMBA/TPA 29:76 by NOR-1/TPA 29:76 Inducible cyclooxygenase 25:47 inhibition of 25:47 Inducible nitric oxide synthase 2547 inhibition of 25:47 Inductive action 23:579 of sonic hedgehog 23:579 Infantile autism 30:376 hippocampal neurons in 30:376 Infantile convulsion 22"511,512,518, 519,521,535 Allium cepa L. for 22:511 Aneilema scapiflorum for 22:512 Arossostephium chinese L. for 22:518 Crossostephium chinese L. for 22:518 Desmodium pulchellum for 22:519 Ferula alliacea for 22"521 Ficus capensis for 22:521 role of HMG-CoA-Inhibitors in 22:250 Verbasum thapsus L. for 22:535 Infesting microorganisms 21" 103 Inflammation 24:893-895;28:202; 30"192,224,225,732 COX-2 enzyme in 30:192 isoliquirtin in 24"893-895 pro-nociceptive prostaglandins in 30:192 role of free radicals in 30:224 role ofleukotrienes in 30:225 use ofArtocarpus venenosa against 28:202
1134 Inflammation mediators 30:225 leukotrienes as 30:225 Inflammatory activity 20:531 Inflammatory disorder 30:192 treament by COX-2 inhibitor 30:192 Inflammatory genes 30:319 COX-2 as 30:319 expression of 30:319 interleukin-2 as 30:319 interferon-~, as 30:319 TNF-Gt as 30:319 Inflammatory pain 30:205,204 induction by formalin 30:205 inhibition by incarvillateine 30:204 Inflammatory skin condition 30:206 use ofbrein in 30:206 use of amyrin in 30:206 Influenza 30:407 therapy of 30:407 preventive medicines for 30:407 use of phytochemicals in 30:407 Influenza A 27:108 Influenza A treatment 27:108 role of amantadine 27:108 Influenza B 27:108 Influenza infection 27:103 Influenza virus 27:107,108;30:289, 395,407,408 enzyme mechanism of 27:114 in vitro 30:408 inhibitor of 30:395 representation of 27:107 Influenza virus replication 30:408 effect of sulphated polysaccharide (PS) 30:408 Ingenol 20-hexadecanoate 29:103 activity in mam-2 bioassay system 29:103 Ingenol type diterpenes 24:288 anti-tumor activity of 24:288 Inhibit LDL oxidation 25:946 Inhibitins 7:119 of aminoglycopyranoses 7:47 of 1 thio [3-D-galactopyranosides 7:48
Inhibition 23:239;25:45-46,66,313,331, 344,512,615 of 4-(methylnitro samino)-l-( 3pyridyl)- 1-butanone (NNK) induced lung tumors 25:46 of 5-1ipoxygenase 25:47 of 12-1ipoxygenase 25:47 of 15-1ipoxygenase 25:47 ofadenylyl cyclase 25:532 of adjurant induced polyarthritis 25:46 of arachidonic acid 25:66 of arachidonic acid induced edema 25:46 offl-hematin aggregation 25:342,354 of bradykinin induced edema 25:46 of capsaicin induced edema 25:46 of carrageenan induced edema 25:46 of cotton pellet granuloma 25:46 of cycloxygenase 25:47 of Epstein-Barr virus early 25:46 of eukaryate signal transduction componenets 25:512 of falcipain 25:331 ofheme polymerizations 25:348 ofheme sequestration 25:348 ofhemozoin 25:354 of histamine release 25:47 of human leucocyte elastase 25:47 of hylauronidase 25:47 of inducible cyclooxygenase 25:47 of inducible nitric oxide synthase 25:47 of DMBA/TPA induced skin tumor 25:48 of lyso PAP acetyltransferase activity 25:615 4-(methylnitrosamino)-l-(3pyridyl)- 1-butanone (NNK) induced lung tumors 25:46 of protein kinase C 23:239 Inhibition 7:47,48;9:581 Inhibition of LTCa-release 27:691
1135 Inhibition of PGE2-release 27:690 from peritoneal macrophages 27:690 Inhibitor 23:68;24:1085;25:542,544, 546;30:836 of 1AA oxidation 25:657 of calmodulin 25:706 of CDPK 25:542,546 of cell adhesion 24:1085 of EFEs 30:836 of enzymes 9:515 of gram-positive bacteria 23:68 of human synovial PLA2 25:697 ofkinesin motors 25:695 of PKA 25:541 of PMA 25:938 of protein phosphatases 25:707 ofsterol biosynthesis 25:303 of vitamin-D-metobolism 9:515 offl-hemetin 25:357 Inhibitory action 27:402 of chitosan 27:402 Inhibitory activity 12:332;21:98,193, 263,270,312,398,430,585,589,591, 594,643,659,670,673,675,690;23:59, 216,808;26:217;28:481 ;30:629 against bone resorption 21:720, 721 against H+,K+-ATPase 21:719 against Staphyllococcus aureus 30:629 mechanism action of 30:225 of (-)-(8,8a-di-epi-swainsonine 12:325 of (-)-swainsonine 12:327 o f (+)-castanospermine 12:332 of benzalmalonates 9:225-227 of honokiol 26:217 of inumakilactone A 28:481 of inumakilactone B 28:481 of inumakilactone C 28:481 of machilin A 26:217 of matairesinol 26:217 of mitogen-induced arctigenin 26:217 ofnagilactone A 28:481 ofnagilactone B 28:481 of nagilactone C 28:481 ofpodolactone A 28:481
ofpodolactone B 28:481 ofpodolactone C 28:481 of podolactone D 28:481 ofpodolactone E 28:481 of rifamycine-type ansamycine antibiotics 23:59 of taurospongin A 23:216 on blastogensis 26:217 Inhibitory activity against human epidermoid carcinoma 24:848 Inhibitory effect 21:695,701,719; 23:311-316,318,445,673,721 ;24:226, 849;25:55;27:437;30:396,594,801 celafoin C-1 23:673 celafolin D-2 23:673 in vitro 30:396 of ailanthone 23:318 of ailantinol A 23:315 ofalienanin B 23:445 of amarolide 23:315,318 ofbrucein D 23:312 ofbudlejasaponin IV 27:689, 690,691 of carp extract 27:440,689 ofcelafolins B-2 23:673 ofcelafolins C-1 23:673 ofcelafolins D-2 23:673 of chitosan 27:437,440 of curcumine 23:316 of DAGO 30:801 of dermorphin 30:801 of dihydroagarofuran sesquiterpenes 23:673 of ginseng saponins 27:423 of H+,K*-ATPase 21:701,719 ofHernandia sp. 30:594 ofmaytansinoids 23:721 of morphine 30:801 of natural quassinoids 23:311 ofneoquassin 23:314,318 of nigakihemiacetal D 23:318 of nigakihemiacetate D 23:318 of nigakilactone F 23:313 ofpicrasin B 23:313 ofsandrosaponin I 27:689,690, 691,693 of SDB 21:695 of SDC 21:695
1136
of semi-synthetic quassinoid 23:311,319 of shinjudilactone 23:318 of shinjulactone A 23:315 of triptofordin F-2 23:673 of triptogelin A- 1 23:673 of yadanziolide C 23:312 of ~t-agonists 30:801 on bone resorption 21:702 on croton oil-induced inflammatory edema 25:55 on Epstein-Barr virus activation 24:849 on gastric acid secretion 21:701 on H§247 21:701 on HHPA 25:55 on HIV replication 30:396 on HSV-1 replication 21:695 on TPA 25:55 Inhibitory effects on chemical carcinogenesis 24:215-264 of flavonoids 24:215-264 ofrotenoids 24:215-264 of steroids 24:215-264 of triterpenoids 24:215-264 Inhibitory mechanisms 30:318 of emodine 30:318 Inhibtion 25:477 of hepatocyte apoptosis 25:477 Insect antifeedant 2:288 Insect antifeedant activity 23:319 of natural quassinoids 23:319 of semi-synthetic quassinoid 23:319 Insect cell-based bioassays 29:30 cyasterone activity in 29:32 2-deoxy-20-hyroxyecdysone activity in 29:32 14-deoxymuristerone A activity in 29:32 2 [3,3[3-dihydro xy- 513-chole st-7en-6-one activity in 29:32 3 [3,14a-dihydroxy-5 [3-cholest-7en-6-one activity in 29:32 ecdysone activity in 29:32 313-hydroxy- 5 [3-chole st- 6-one activity in 29:32 20-hydroxyecdysone activity in
29:32 inokosterone activity in 29:32 Kc cell bioassay as 29:30 makisterone A activity in 29:32 muristerone A activity in 29:32 podecdysone A activity in 29:32 ponasterones activity in 29:32 213,313,513,14a-tetrahydro x ycholest-7-en-6-one activity in 29:32 2[3,3~ ,25-tridihydroxy- 513cholest-6-one activity in 29:32 viticosterone E activity in 29:32 Insect control 21:611 Insect juvenile hormone analogues 14:391-397 from thujone 14:391-397 Insect pheromones 11:415-417 via diisopropylethanediol esters 11:415-417 Insect repellant 5:757 Insecticidal activity 18:229,704;21:252, 254,262,266,267,269,270,271,278, 285,379,595,611;23:666;667,670, 677,678;24:25,799,845,866;26:231, 232,426,471,479,485;28:477; 30:153-154,695 biological activity 24:25,799,845 bioassay of 24:866 of 14-epi-ponolactone A 28:477 ofanacardic acid 30:153-154 ofcelastrus angulatus 23:666 ofhallactone A 28:477 ofhallactone B 28:477 of lemon juice phenolics 23:748 oflollo rosso 23:759 ofnagilactone A 28:477 ofnagilactone C 28:477 ofnagilactone D 28:477 ofnagilactone E 28:477 ofpodolactone A 28:477 ofpodolactone C 28:477 of podolide 28:477 of quinone methides 30:695 of red lettuce anthocyanins 23:760 of red onion anthocyanins 23:762
1137 of Romaine lettuce phenols 23:761 ofsellowin A 28:477 of sesquiterpene alkaloids 23:678 of sesquiterpenes 23:667,670 Insecticidal assay 21:273,276,281,284 Insecticidal effects 26:852,1136 of ryanodol-type diterpenes 26:852 of isoryanodol-type diterpenes 26:852 Insecticidal properties 21:225 Insecticidal sesquiterpenes 23:668 from Euonymus bungeanus 23:668 Insecticidal Stemona alkaloids 21:759 Insecticides 7:395-397;21:110;28:390 used of essential oil 28:415,390 Insositol- 1,4,5-triphosphate (IP3) receptor 25:534 Insulin signalling activated protein kinase 25:522 Insulin-responsive protein kinase (PKB) 25:517 Integramycin 28:147 as HIV-integrase inhibitor 28:147 Integrase 30:226 cleaveage of 30:226 role in HIV 30:226 Interferon 4:273;25:519 LPS induction of 4:199 Interferon gamma (IFN-y) 30:689 inhibitory effect on 30:689 production of 30:689 Interferon production 12:390 by human cell cultures 12:390 protein kinase in 12:390 Interferon 7 (IFN-7) 25:431,464,477; 26:951 Interferon-ot-13 and ~, 20:531-533 Interleukin I 5:388 Interleukin I induction 4:197 by LPS 4:197 Interleukin- 1 (IL- 1) 30:689 by synovium 30:689 production of 30:689 Interleukin-2 25:536 Interleukin-2-dependent (IL-2) 25:271
Interleukin-6 cytokine family 25:717 Imerleukin-8 25:711 Interleukins 25:271,540 (+)-Intermedeol 14:450,451 biological activity of 14:450,451 Intestinal calcium transport 30:484,497 assay for 30:497 of lc~,25(OH)2D3 30:497 role of vitamin D2 in 30:484 Intestinal diseases 30:224 role of free radicals in 30:224 Intraerythrocytic antimalarial activity 25:343 Intraerythrocytic cycle 25:329 Intraerythrocytic phase 25:327,328,329 Intrapetacin A 28:66 anti-fungal activity of 28:66 Intrapetacin B 28:66 anti-fungal activity of 28:66 Intrasinusoidal hematosis 25:464 Intrinsic activity 30:596,816 in vivo 30:596 of alkaloids 30:596 of central opioid receptors 30:816 of DER 30:816 of glycopeptides 30:816 Inuviscolide 29:90 activity in TPA assay system 29:90 Invertase inhibition 21:593 Ion channel blockers 22:16 Ion gradient generating ATPase 25:512 cz-Ionone 28:406 acaricidal properties of 28:406 Ionophone A23189 25:274,275,940 Ionophore activity 4:93;18:857 Ionophoric antibiotics 21:303 Ionotropic receptor 30:192,193 heat-activated channel TRPVI typeof 30:193 role in nociceptor depolarisation 30:192 role in tetrodotoxin-resistant sodium channels 30:193 role in vanilloid receptors 30:193 TRPM8 type of 30:193 IP3 receptors Ca 2+ channel 25:534 IP3-gated Ca 2+channels 25:517
1138 IP3-induced release of Ca 2+ 25:488 IP3-Inositol- 1,4,5-triphosphate 25:516 Ipolamiide 29:84 activity in CRG, B RK, HST assay systems 29:84 Ircenals 24:573,615,667,669 anti-bacterial activity of 24:573 anti-leukemic activity of 24:573 Ircinia spinulosa 28:676 brine shrimp toxicity of 28:676 Irciniasulfonic acid 28:714 reverses multidrug resistance 28:714 Iridoids 24:510-521 analgesic activity of 7:490 antidote for c~-amanitin poisoning 7:490 antileukemic activity of 7:490 antiphlogistic activity of 7:490 antitumor activity of 7:490 as antiviral compound 24:510-521 biological activity of 7:490 diuretic activity of 7:490 hepatoprotectivity of 7:490 hypotensive activity of 7:490 uterine contracting activity of 7:490 Iron responsive element 26:951 Irreversible cytotoxicity 15:447 Irreversible inhibitors (suicide substrates) 7:36-40 Irritable bowel syndrome 30:368 role of serotonin (5-HT) 30:368 Ischaemia reperfusion 22:438;25:610, 614 Isoalvaxanthone 28:230 biological activity of 28:230 Isoantibodies 29:542 antigen of 29:542 Isocajucarinolide 29:100 activity in TLO assay system 29:100 2-Isocephems 12:126 antibiotic activity of 12:126 Isocurcumenol 29:90 activity in HPT assay system 29:90
Isodeoxypodophyllotoxin 26:213 cytotoxicity of 26:213 Isoderrone 28:228 biological activity of 28:228 Isoescin Ia (triterpene saponin) 29:575 effects on HIV- 1 protease 29:575 Isoeugenol 26:227 antibacterial activity of 26:226 Isoflavones 28:268,269,286,287 oestrogenic activity of 28:268 Isofraxidin 5:515,520,7:117,120,204, 224 anticancer activity of 5:521 sedative activity of 5:521 Isogemichalcone C 28:16 as aromatase inhibitor 28:16 Isoglycyrol 28:224,228,241 anti-Helicobacter pylori activity of 28:241 anti-microbial activity of 28:224 biological activity of 28:228 (+)-Isogmelinol 26:241 as PAF-induced inhibitor 26:241 Isogmenolin 26:241 as PAF-induced inhibitor 26:241 Isohelenin 29:87 activity in EBV assay system 29:87 activity in iNOS, NFkB assay systems 29:87 activity in TPA, AA, PLA assay systems 29:91 Isohumulones 24:902-904 anti-hyperglycemic effects 24:902-904 Isoiguesterol 30:693-695 against drug-sensitive strain NFs4 30:694 against multidrug-resistant strain K1 30:694 Isoindoline 8:397-403 as a2 agonists 8:397-403 Isolicoflavonol 28:17,224,243 anti-Helicobacter pylori activity of 28:243 anti-microbial activity of 28:224 as aromatase inhibitor 28:17
1139
(+)-trans-Isolimonene 29:83 activity in AM assay system 29:83 Isoliquiritigenin 28:228 biological activity of 28:228 Isoliquirtin 24:893-895 inhibitory effect in inflammation 24:893-895 Isolobophytolide 8:15,19-32 antitumor activity 8:15,19-32 (+)-Isomenthol 29:83 activity in AM assay system 29:83 (-)-Isomenthone 29:83 activity in AM assay system 29:83 Isoorientin (luteolin 6-C-glucoside) 29:579 effects on ACE 29:579 2-Iso-oxacephems 12:126 antibiotic activity of 12:126 Isopetasin 29:87 activity in 5LOX, PLA assay systems 29:87 Isoprenylated flavonoids 28:199,203, 207,244 biological activity of 199 effect on testosterone 5c~reductase 28:244 from medicinal plants 28:199 hypotensive action of 28:207 Isopulmericin 16:299 antifungal activity of 16:299 antileukemic activity of 16:299 cytotoxic activity of 16:299 Isoquercitrin (quercetin 3-O-glucoside) 29:573 effects on HIV- 1 protease 29:573 Isoquercitrin (Quercetin 3-0glucoside) 29:579 effects on ACE 29:579 Isoquinoline 25:542;30:563-567,588 against cancer cell lines 30:588 based PKA inhibitor 25:542 from genus Hernandia 30:563-567 Isoquinoline alkaloids 30:560,562,588, 590,594,597
against cancer cell lines 30:588 antiplatelet aggregation activity of 30:560 cytotoxicity of 30:560 Epstein-Barr virus inhibition due 30:560 Isoquinoline quinones 10:77-145 as antibiotics 10: 77-145 Isorhamnetin (3,5,7,3',4'-pentahydroxy-flavone 3'-methyl ether) 29:577 effects on N-aminopeptidase 29:577 Isoryanodol-type diterpenes 26:852 insecticidal effects of 26:852,1136 Iso-steviol activity 29:100,101 Isovanillin 30:567,594 as platelet aggregation inhibitor 30:594 Isovitexin (apigenin 6-C-glucoside) 29:579 effects on ACE 29:579 Isoyangambin 26:242 as PAF-induced inhibitor 26:242 Ivermectin 28:396 as macrolide antibiotic 28:396 Ivermectin (22,23-dihydroavermectin Bi) 12:8,9 biological activity of 12:8,9 JAK/STAT- linked receptors 25:520 JAK/STAT pathway 25:519 Janolusimide 28:146 from Janolus cristatus 28:146 neurotoxic lipophilic activity of 28:146 Jasmonic acid 27:64,71-73 biological activities of 27:72,73 Jaspamide (jasplakinolide) 5:429 anthelmintic activity of 5:429 antifungal activity of 5:428 insecticidal activity of 5:428 Jaspisin 28:697 sea urchin hatching inhibition by 28:697 Jaundice 22:643
1140
JB6 cell line 30:593 tumor-promotion in 30:593 JB6 cell line transformation 30:592 inhibition of 30:592 Jenisseensosides A-D 26:46 cyclooxygenase inhibitory activity of 26:46 Jenisseensoside C 26:47,55 granulocyte phagocytosis of 26:47,55 Jenisseensoside D 26:47,55 granulocyte phagocytosis of 26:47,55 Justicidin B 26:243 as PAF-induced inhibitor 26:243 Justicidin E 26:243 as PAF-induced inhibitor 26:243 Juvenile hormone (JHI) 1:704-707 synthesis of 1:704-707 Juvenile hormone 25:546 Juvenile hormone III 1:704,705;22:369, 370,371 from Coleoptera 22:371 from Dictyoptera 22:371 from Hymenoptera 22:371 from Isoptesa 22:371 from Lepidoptera 22:371 from Orthoptera 22:371 synthesis of 1:704,705 Juvenoid activity 22:384 Juvenoid effects 22:386 ofjuvabione 22:386 Juvenoids 22:383,395
K § channels 25:530-531,534 K+-channel mediated ion transport 25:497 K-252a ("SF-2370") 12:366,368 K-252b 12:384 protein kinase C inhibitor of 12:384 K-252c (staurosporinone) protein kinase inhibitor of 12:386 K-252d 12:366,368,369,386 protein kmase inhibitor of 12:386
K-25a 12:366,368,369,384,390,395, 396,398,399 anihypertensive activity of 12:398 antaillergic effect of 12:398 antiinflammatory effect of 12:398 antitumor activity of 12:395 effect on nerve growth factor 12:396 porcine spleen protein kinases inhibitor of 12:390 prostaglandin production by 12:399 protein kinase A inhibitor of 12:384 protein kinase C inhibitor of 12:384,390 protein kinase G inhibitor of 12:384 K562 cells study 27:877 KA-antibiotcs in carbapenem 4:434 Kadsurenin H 26:240 as PAF-induced inhibitor 26:240 Kadsurenone 26:240 as PAF-induced inhibitor 26:240 Kaempferol (flavonol) 29:573 effects on HIV- 1 protease 29:573 Kaempferol 3-O-(2"-[3-D- xylopyranosyl)-ot-L- rhamnopyranoside 28:64, 65 anti-oxidant activity of 28:64,65 Kaempferol 3-O-c~-L-rhamnopyranoside 28:64 Kaempferol-3-O-(2"-O-galloyl)glucoside 29:579 effects on ACE 29:579 Kahweol 29:101 activity in skin-6 bioassay syste m 29:101 activity in CYP bioassay system 29:101 activity in GSH bioassay system 29:101 activity in GST bioassay system 29:101
1141
Kainic acid-binding glutamate receptors 25:529 Kala-azar 2:302 Kalopanax pictus 30:203 use in rheumatoid arthritis 30:203 Kalopanaxsaponins-A 30:203 antinociceptive effect of 30:204 Kalopanaxsaponins-I 30:203 antinociceptive effect of 30:204 kappa-opioid receptor 30:205 activation by (+)-allomatrine 30:205 activation by (+)-matrine 30:205 kappa-opioid receptor activation 30:207 by menthol 30:207 Kamebacetal A 29:101 activity in NFkB bioassay system 29:101 activity in NO bioassay system 29:101 Kamebakaurin 29:101 activity in NFkB bioassay system 29:101 activity in NO bioassay system 29:101 Kamebanin 29:101 activity in NFkB bioassay system 29:101 activity in NO bioassay system 29:101 Kampanols 24:449-450 biological activity of 24:450 structures of 24:449 Kampo medicines 24:875-926 active compounds of 24:878 anti-angiogenesis action of 24:875-925 anti-hyperglycemic action of 24:875-925 anti-inflammation action of 24:875-925 anti-proliferation action of 24:875-925 blood glucose regulatory action of 24:875-925 blood vessel contraction of 24:875-925
blood vessel relaxation of 24:875-925 chemical-structure-activity of 24:875-925 neuromuscular blocking action of 24:875-925 pharmacological activity of 24:875-926 smooth muscle contraction of 24:875-925 smooth muscle relaxation of 24:875-925 Kanzonol B 28:229 biological activity of 28:229 Kanzonol G 28:229 biological activity of 28:229 Kanzonol H 28:229 biological activity of 28:229 Kanzonol P 28:229 biological activity of 28:229 Kanzonol R 28:229 biological activity of 28:229 Kanzonol S 28:229 biological activity of 28:229 Kanzonol U 28:229 biological activity of 28:229 Kanzonol V 28:229 biological activity of 28:229 Kanzonol W 28:229 biological activity of 28:229 Kanzonol X 28:229 biological activity of 28:229 Kanzonol Y 28:229 biological activity of 28:229 Kappa receptors 22:24 Kappa-carrageenan 26:1148 Karamatsuic acid methyl ester 29:99 activity in EBV assay system 29:99 I~ATpchannels 25:534 Kaur- 16-en- 19-oic acid 29:100 entactivity in NFkB bioassay system 29:100 activity in EBV bioassay system 29:100 Kazinol A 28:17 antioxidant activity of 28:17 as tyrosinase inhibitor 28:17
1142
as platelet aggregation inhibitor 28:17 Kazinol B 28:17,226,230 anti-human immunodeficiency virus (HIV) activity of 28:226 as cyclooxygenase 28:17 as platelet aggregation inhibitor 28:17 biological activity of 28:230 Kazinol F 28:16,210,230 antioxidant activity of 28:16 as tyrosinase by inhibitor 28:16 biological activity of 28:230 Kazinol N 28:230 biological activity of 28:230 KB cells cytotoxicity assay 30:733 determination of cytotoxic activity 30:733 KB-1 28:229 biological activity of 28:229 KB-16 (human oral epidermal carcinoma) 30:588 activity of (-)-deoxypodophyllotoxin against 30:588 activity of (-)-yatein against 30:588 KB-3 28:229 biological activity of 28:229 K-cells-IL2-activated killer cells 25:273 effect ofActinoplanes sp. 25:777 KCI-depolarized rat portal vein 30:748 KDN 30:421,422,433,440,444,448,462 in cancer cells 30:422 in human fetal card red blood cells 30:422 oncotetal antigen properties of 30:422 Keenamide A 28:652 as cyclic hexapeptide 28:652 as cytotoxic agent 28:652 Ketonucleosides 4:234,253,19:512 biological activity in 4:253 Kidamycin "aglycone" 11:136 as antitumor antibiotics 11:136 Kidney disorders 26:50 Herniaria hirsuta in 26:50 Kidney disturbances 30:207 use of Phyllanthus (genus) in 207
Kinesin motors 25:695 inhibitor of 25:695 Kinin formation 30:204 inhibition of 30:204 Km values 30:95 oflipase activity 30:95 Krameria triandra 26:204 scavenging activity of 26:204 KSD assay 25:862 KT-5926 12:388 myosin inhibitor of 12:388 protein kinase inhibitor of 12:385,386 Kuehneromycin A 29:128,129 effect on reverse transcriptases 29:128 Kumatakenin 28:226,229 anti-human immunodeficiency virus (HIV) activity of 28:226 biological activity of 28:229 Kuwanon 28:212 biological activity of 28:212 Kuwanon C 28:230 biological activity of 28:230 Kuwanon G 28:209,221,230 hypotensive action of 28:209 biological activity of 28:230 bombesin receptor antagonist of 28:221 Kuwanon H 28:200,201,209,212,221, 222,223,225 anti-human immunodeficiency virus (HIV) activity of 28:226 as bombesin receptor antagonists 28:223 as GRP-induced DNA synthesis inhibitor 28:222 biological activity of 28:212 bombesin receptor antagonist of 28:221 hypotensive action of 28:200, 209 Kuwanon M 28:212 biological activity of 28:212 Kuwanon R 28:230 biological activity of 28:230 L-1210 leukemia cell 21:403,414
1143
L-653,150 26:242 as PAF-induced inhibitor 26:242 Labda-8(17), 13-dien- 15,12R-olid- 19-oic acid 29:101 activity in EBV bioassay system 29:101 Labdane 25:241,244,256,259,261,266, 275,276,277 activities of 25:257 Labdane F2 29:102 activity in PLA bioassay system 29:102 Lactuca sativa L. 27:215 allelopathic interaction of 27:215 Lagascatriol 29:103 activity in COX bioassay system 29:103 activity in NO bioassay system 29:103 Laminariajaponica Aresch. 30:56 in arteriosclerosis treatment 30:56 in cancer treatment 30:56 in hyperlipidemia treatment 30:56 Lamivudine 24:488 as anti-viral agent 24:488 Lancet-shaped follicular mites 28:410 as cause of demodectic mange 28:410 Lapachol 30:317 teratogenic potential of 30:317 Lapachone antitumor effects 29:744 against A549 human breast cancer cell 29:745 against Cdc25 phosphatases 29:745 against DNA topoisomerase 29:746 against human cancer cell lines 29:744 against ovarian adenocarcinoma 29:744 via DNA modification 29:745 of 2-methyl-(Z)-4-phenylimino) naphth[2,3-d]oxazol-9-one 29:744 proteasome inhibition by 29:746
through multistage carcinogenesis 29:746 Lapidin 29:91 activity in CRG assay system 29:91 Lardoglyphus konoi 1:696 pheromone of 1:696 (+)-Lariciresinol 26:219 as chemopreventive agent 26:219 Larikaempferic acid methyl ester 29:100 activity in EBV assay system 29:100 Larvotoxic 17:102 Laudanosine 30:564,595,596 antimalarial activity of 30:595 antiplasmodial activity of 30:596 effect on antiplasmodial activity 30:596 Laulimalide 30:5 as microtubule stabilizing agent 30:5 (+)-Laurotetanine 30:563,564,589,594 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 as platelet aggregation inhibitor 30:594 cytotoxic effect of 30:589 Lavandula angustifolia 28:412 acaricidal activity of 28:412 Laxative 30:72 use of Angelica keiskei as 30:72 Laxative activity 30:304-307 of anthranoid compounds 30:304-307 Laxative drugs 30:303 aloes as 30:303 caseara as 30:303 rhubarb as 30:303 senna as 30:303 Laxative effect 30:305 of aglycones 30:305 by damaging epithelial cells 30:305 Leaf spot disease 4:601
1144 Lectins 24:523,524 inactivation of (HVF) 24:523,524 Leech repellent 5:745 Leishmania adleria 2:311,313 immunity against kala-azar 2:313 Leishmaniases 2:293;26:781,783, 784,785,793 LELA 29:585 effects on acetyl-11-keto-~boswellic acid (triter-pene) 29:585 Lemmatoxin 7:428 molluscicidal activity of 7:428 Lemmatoxin-C 7:428 molluscicidal activity of 7:428 Lentinan 5:279 antitumor activity of 5:317 Lepidium sativum 28:400 in tick toxicity 28:400 Lesion 22:441 Lethality bioassay 9:385,387,388, of brine shrimp 9:385,387,388, 399,400 Leukemia 1:275 P-388Leukemia 24:190 Leukemia cells 23:74,186 cytotoxic activity against 23:78, 172,177,180,186,234,649,679, 797,800 ofherbimycin A 23:72,74,90 Leukemia HL-60 cells 21:636 Leukemia P-388 19:558;25:760 Leukocyte activity 26:510 Leukocyte degranulation 30:70 inhibitory action on 30:70 Leukocytes 22:112,437;30:59,60, 64,66,67,70 effect of carp oil on 30:66 effect of oleic acid on 30:65 effect of triterpenoid fraction on 30:60 in LLC-bearing mice 30:59,64 inhibitory action on 30:70 Leukocytopenia 26:243 Leukoencephalmalacia 9:215 Leukopenia 5:135;25:431 Leukotriene B4 production 25:615
Leukotriene B4 25:275,617,815,939; 30:70 inhibitory action on 30:70 Leukotriene B4 receptor 25:705 Leukotriene biosynthesis 30:225 inhibition of 30:225 Leukotrienes 1:528;22:126,434,437; 25:274,275,939-940;30:192,225 and macrophages 30:192 as pain mediator 30:192 from arachadonic acid 30:225 LTC4 type of 30:225 LTD4 type of 30:225 LTE4 type of 30:225 peptidoleukotrienes type of 30:225 role in allergy processes 30:225 role in inflammation 30:225 Leurocristine 13:655 from Catharanthus roseus 13:655 Lewis lung carcinoma 19:609;30:59 in vitro 30:59 Libinia emarginata 1:704 juvenile hormone from 1:704 Licania genus 28:35 biological studies on 28:35 Licania heteromorpha var. heteromorpk, 28:62 anti-mic, obial activity of 28:62 Licania licaniaeflora 28:63 anti-oxidant activity of 28:63 Licochalcone 21:740-744 bioactivity of 21:744 Licochalcone A 28:224 anti-Helicobacter pylori activity of 28:241 anti-microbial activity of 28:224 biological activity of 28:229 Licochalcone B 28:226 anti-human immunodeficiency virus (HIV) activity of 28:226 anti-Helicobacter pylori activity of 28:241 anti-microbial activity of 28:224 biological activity of 28:229 Licoflavonol 28:229 biological activity of 28:229
1145 Licoisoflavanone 28:229 biological activity of 28:229 Licoisoflavone A 28:229 biological activity of 28:229 Licoisoflavone B 28:224 anti-Helicobacter pylori activity of 28:241 anti-microbial activity of 28:224 biological activity of 28:229 Licorice 28:204,205 anti-hepatitic principles from 28:205 antitussives from 28:205 anti-ulcer compounds from 28:205 Licorice flavonoids 28:224 anti-Helicobacter pylori activity of 28:234 anti-microbial activity of 28:62,224, 257,293 Licorice-saponin 28:241 anti-Helicobacter pylori activity of 28:241 Licoricidin 28:241 anti-Helicobacter pylori activity of 28:241 anti-microbial activity of 28:62,224,257,293 biological activity of 28:229 Licoricone 28:224 anti-Helicobacter pylori activity of 28:243 anti-microbial activity of 28:224 biological activity of 28:229 Licorisoflavan A 28:229 biological activity of 28:229 Licuraside 29: (Isoliquiritigenin-4-[3D-apio furano syl-2 '- 13-D-Glc; 2',4',4- trihydroxychalcone4- [3-D-apiofuranosyl-2'- [3-Dglucoside 29:589 effects on PEP 29:589 Ligand 30:799,808 opioid receptivity of 30:808 Ligand-gated channel 21:11,14,20 Ligand-gated ion channel 25:527 neurotransmitter receptor 25:527
Lignan constituents 30:588 against cancer cell lines 30:588 Lignans 5:9,459,503,753,754,311; 17:313,441 ;20:108-113,273,613; 24:215,228-232,503-509,739-798; 26:229,790,813,887;30:560,562,567, 570,590,594 antileishmanial activity of 26:229,790,813,887 antiplatelet aggregation due to 30:560 antiperoxidative effects of 26:249-255 as antiviral compound 24:503509 biological activity of 5:505,544, 545;24:739 cytotoxicity due to 30:560 Epstein-Barr virus inhibition due to 30:560 parasiticidal activity of 26:229 turbidimetry assay 30:594 Limbic brain regions 30:383 serotonin (5-HT) receptors in 30:383 Limonen-l,2-oxide 29:83 activity in lung-l, RAS bioassay system 29:83 d-Limonene 29:83 activity in AM assay system 29:83 activity in GPx assay system 29:83 activity in GST assay system 29:83 activity in NFkB assay system 29:83 activity in RAS assay system 29:83 activity in mam-1 assay system 29:83 activity in mam-2 assay system 29:83 activity in stoma assay system 29:83 activity in AM assay system 29:83 activity in TPA assay system 29:83
1146
activity in liver-1 assay system 29:83 activity in lung-1 assay system 29:83 activity in AM assay system 29:83 Limonene- 1,2-diol 29:83 activity in RAS assay system 29:83 Linalool 28:406;29:83 acaricidal activity of 28:412 acaricidal properties of 28:406 acaricidal property of 28:406 activity in RAS assay system 29:83 activity in TPA assay system 29:83 Linearol 29:100 activity in NFkB bioassay system 29:100 Lipases 24:1005 enzymatic activity 24:1005 Lipasic 24:999-1001 enzymatic activity 24:999-1001 Lipid A 28:518,519,523,525,526, 529,534,537,538 acute effects of 28:523 antitumor activities of 28:518 association with immunomodulators 28:534 biological properties of 28:519 effect on acquired immunity 28:529 effect on cytokine production 28:526 effect on innate immunity 28:525 in cancer vaccination 28:537 to treat tumor-bearing animals 28:538 treatment with 28:534 Lipid A DT 5461 28:534 for C38 colon carcinoma 28:535 for Lewis lung carcinoma 28:535 for MH134 hepatoma 28:535 for MM46 mammary carcinoma 28:535 for murine Meth A fibrosarcoma
28:535 treatment with 28:534 Lipid A OM-174 28:536 antitumor activity of 28:536 treatment with 28:536 Lipid A ONO-4007 28:535 treatment with 28:535 Lipid A tolerance 28:521 by anti-LPS antibodies 28:522 Lipid oxidation 23:767 measurment of 23:768 Lipid oxidation system 23:773 Lipid peroxidation 4:495;27:59,68,85, 504,505 inhibitor of 4:495 oflinoleic acid 27:68 relation with apoptosis 27:86-88 Lipid peroxidation activity 26:253 Lipid peroxidation products 27:84-86 in biological materials 27:84-86 relation with cell death 27:86-88 Lipid storage disease (phytoesterolemia) 9:478 Lipids 28:517 anti-tumor activity of 28:517 Lipid-soluble antioxidant 30:322 uniquinone as 30:322 Lipo-CCK biological properties of 18:857863 Lipo-gastrin 18:844-848 biological properties of 18:844848 physical properties of 18:844848 Lipogenesis 27:393 biological activity of 27:393 insulin-induced 27:397 Lipolysis 27:393 biological activity of 27:393 Lipolytic action 27:394 activity of 27:394 Lipolytic activity 23:364 of coumarin 23:335,356,357, 353,368,376,393,550,553 J3-Lipomycin 28:135 as antibacterial agent 28:135 ot-Lipomycin 28:135 as antibacterial agent 28:135
1147
Lipooxygenase pathway 25:263 Lipooxygenases 25:597,939,940 Lipoperoxidation assay 25:940 Lipoperoxidation process 25:614 Lipophilic antioxidant 30:224 design of 30:224 Lipophilicity 4:369 Lipopolysaccharides (LPS) 28:518,520, 521,523,528,533,539;30:420 acute effects of 28:523 antigenic properties of 28:518 biological properties of 28:518 by PROb colon cancer cells 28:533 components of 30:420 effects on angiogenesis 28:528 effects on blood flow 28:528 in human macrophages 28:521 in peritoneal carcinomatosis 28:533 of gram-negative bacteria 30:420 phase I trials with 28:539 receptor for 28:520 role in immunospecificity 30:420 12-Lipoxygenase 25:47 inhibition of 25:47 15-Lipoxygenase 25:47 inhibition of 25:47 5-Lipoxygenase 25:47;30:225 inhibition of 25:47 redox inhibitors of 30:225 Lipoxygenase catalysis 9:559-589 products of 9:559-589 5-Lipoxygenase inhibition 30:225 effect of polyhydroxylated 2phenylnaphthalenes 30:225 effect of tetrahydroxypavinan 30:225 5-Lipoxygenase inhibitor 28:215; 30:226 artonin E as 28:201,215 IC50 values of 30:226 5-Lipoxygenase inhibitory activity 2:282,284,335;24:855 of Magnolia liliflora 24:855 Lipozyme activity 20:845 Liquiritigenin 28:241 anti-Helicobacter pylori activity
of 28:241 anti-microbial activity of 28:224 Liquiritin 28:241 anti-Helicobacter pylori activity of 28:241 anti-microbial activity of 28:224 L&teria infection 25:431 ;30:766,768 host defense against 30:766 late phase of 30:769 protective mechanism against 30:766 stage of 30:768 with LP-BM5 MuLV 30:766 with murine leukemia viruses 30:766 L&teria monocytogenes 30:766,767,773 host defense against 30:766 in immune response 30:773 Listeria-specific antigens 30:770 Listeria-specific cell mediated immunity 25:431 Listeria-specific cell-mediated immunity 30:768 development of 30:768 Litholytic properties 26:52,54 of Herniariafontanesii 26:52,54 Lithospermic acid A 30:227 as HIV-1 integrase inhibitors 30:227 structure of 30:227 Lithospermic acid B 30:227 as HIV- 1 integrase inhibitors 30:227 structure of 30:227 Lithospermic acids 30:226 effect on HIV-1 infected H9 cells 30:226 Liver 30:64 metastasis in 30:64 Liver cancer 20:528 Liver carcinoma 30:406 Liver disorders 30:637 role of oleanolic acids in 30:637 Liver hepatocytes 30:406 Liver injury 25:461 ;30:637 effect of LPS toxicity on 25:461 effect of TNF-a 25:470 role of oleanolic acids in 30:637
1148
Liver insufficiency 26:1130 as syndrome type-lA 26:1130 Liver intoxication 25:459-462 with D-Gal N/LPS 25:459-461 with D-gal N/TNF-a 25:460,461 Liver metastatic tumor colonies 30:66 effect of oleic acid on 30:65 Liver necrosis 30:406 Liver tumor model (H22) 30:841 effect of Eisenia fetida 30:841 Liver-derived NO 25:471 Livestock 30:751 toxic disease 30:751 LLC cells 30:65 intrasplenic implantation of 30:65 LLC cells DNA synthesis 30:67,68 effect of oleic acid on 30:67,68 LLC tumor metastasis 30:60 effect of triterpenoid fraction on 30:60 inhibition of 30:60 LLC-bearing mice 30:59,61 leukocytes in 30:59 tumor in 30:61 LL-Z1271(x 28:473 anti-fungal activity of 28:473 L-norepinephrine 25:530 Locomotor activity 21:749 Loliolide 29:111 activity in EBV bioassay system 29:111 Lonophores 25:374 Lonotropic glutamate receptors 25:528 Lonotropic receptors 25:528 Lonotropic serotonin receptors 25:529 Loperamide 30:200 antidiarrheoal activity of 30:200 Loreainide 30:200 antiarrhythmic activity of 30:200 LoVo tumor cell 21:165 LPLC 7:407,408,410,415,418 antigenic specificity of 4:195 6-deoxy-D-mannoheptose in 4:195 interleukin I induction by 4:197 LPS 25:466 hepatic intoxication with 25:466 LPS hepatotoxicity 25:461,462
LPS induced liver injury 25:475 LPS induced lung injury 25:475 LPS stimulation 25:475 LPS toxicity 25:461 effects on liver injury 25:461 LPS-beated macrophages 25:473 LPS-elicited hepatocyte apoptosis 25:463 LPS-elicited liver injury 25:463 LPS-induced Ca2§ elevation 25:475 LPS-induced hepatocyte apoptosis 25:463,471 LPS-induced nitric oxide 25:471 LPS-induced TNFa production 25:470 LPS-related liver injury models 25:463 LPS-stimulated TNF-a production 25:470 LTP-blocking effect 25:966 of ethanol 25:966 Lumbricus rubellus (humus earthworm) 30:826-828,833 assay of 30:833 Lung tumors 25:46 induced by 4-(methylnitrosamino)-l-(3- pyridyl)- 1butanone (NNK) 25:46 Lupane triterpenoides 24:457 FPTase inhibition by 24:457 Lupeol (fagasterol; monogynol B;~3viscol) (lupane triterpene) 29:587 effects on CHY 29:587 Lupeol palmitate (lupeol hexadecanoic acid ester) 29:587 effects on CHY 29:587 Lupine alkaloids 27:258 biological activity of 27:258 Lupus nephritis 26:269 Luteolin (5,7, 3',4'-tetrahydroxyflavone) 29:579 effects on ACE 29:579 effects on HIV- 1 protease 29:573 effects on NEP 29:581 effects on PEP 29:589 Lutinizing hormone-releasing hormone 27:794,796 Lycogala epidendrum 29:230,231 anti HSV-I virus activity of 29:230
1149
Lycopene 30:525 in prostate cancer prevention 30:525 Lydicamycin 28:126 as antibacterial agent 28:126 Lymphatic filariasis 12:9 T-Lymphoblast cells 19:556 Lymphocyte proliferation 27:693 Lymphocyte transformation 25:224, 225,226 Lymphocytes 15:369 Lymphocytic leukemia 21:158;26:925 Lymphocytic leukemia system 18:696 Lymphoid leukemia 4:723 Lymphokine-activated killer 26:923, 951 Lymphokines 25:271 Lyngbya majuscula 11:278 lyngbyatoxin from 11:278 Lyngbya toxin A 5:412 cytotoxic activity of 5:411 Lyngbyatoxin 11:278 from Lyngbya majuscula 11:278 Lypooxygenase inhibition 25:617 Lypooxygenase pathway 25:274 Lyso PAP acetyltransferase activity 25:615 inhibition of 25:615 Lysolipins 29:317 effects on bacteria 29:317 lytic activity of 29:317 M~ and M3Receptor 21:18 Macarangaflavanone b 28:229 biological activity of 28:229 mAch receptors 21:108 Machililin G 26:242 as PAF-induced inhibitor 26:242 Machilin A 26:217 inhibitory activity of 26:217 Macrocyclic trichothecenes 30:751 in vivo toxicity of 30:751 inhibition of protein synthesis 30:751 paralysis of skeletal muscles due to 30:751 respiratory depression due to 30:751
et2-Macroglobulin 30:836 aspartate inhibition by 30:836 cysteine inhibition by 30:836 metallo-proteases inhibition by 30:836 serine inhibition by 30:836 Macrolide antibiotics 21:373;29:321 against Caenorhabditis elegans 29:321 against human tumors 29:321 ansamitocin P3 as 29:321 antitumor activity of 29:322 antiviral effects of 29:322 as vitamin K antagonist 29:322 chlorothricins as 29:322 colubricidin A as 29:321 cytotoxicity of 29:321 in carcinoma 29:321 in leukemia 29:321 naphtomycins as 29:322 nematocidal activity of 29:321 roseophilin as 29:322 Macrolide antibiotics 3:277-281; 5:606,609,613;195 ;13:155-185,664 acetylspiramycin 5:609 difficidin 5:609 erythromycin 5:609 oleandomycin 5:609 oxydifficidin 5:609 Macrolides 3:277-281 ;4:513-520; 5:609,356,357,6:272-277 ;9:246, 247,290;8:175-201,222;16:658-662 Macrophage prostaglandins 22:25 Macrophage-mediated cytotoxicity 26:910 Macrophages 25:473 effect of TNF-a 25:473 Maerolides 24:541-544 as antiviral compound 24:541544 Magainin-2 27:807 anticancer activity of 27:807 (+)-Magnoflorine 30:564,589 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:589
1150
Magnolia biondii 24:845,854 PAF antagonists of 24:854 Magnolia fargesii 24:854,862 PAF antagonists of 24:854 Magnolia liliflora 24:854,855,860 5-1ipoxygenase-inhibitory activity of 24:855 neurotropic activity of 24:854 Magnolia spp. 24:845-873 biologically active compounds from 24:845-873 Magnolol 24:861;26:240;29:582 anti-fungal activity of 24:861 as PAF-induced inhibitor 26:240 effects on MMP 29:582 Magnone A 26:245 as PAF-induced inhibitor 26:245 Magnone B 26:245 as PAF-induced inhibitor 26:245 Magnosalin 24:888-890 inhibitory effect on ECs 24:888-890 inhibition of angiogenesis 24:888-890 Makaluvamine A 29:253 as topoisomerase II inhibitor 29:253 Malaria 26:804;30:561,597 treatment of 26:804 use of Hernandia
moerenhoutiana
in 30:561 use of Hernandia nymphaeifolia in 30:561,597 use of Hernandia voyronii in 30:561,597 Malaria pigment 25:332 Malarial fever 28:202 use of Artocarpus venenosa against 28:202 (+)-Malekulatine 30:584,566,590,594 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 as platelet aggregation inhibitor 30:594 cytotoxic effect of 30:589
Malignant tumors 21:158;30:841 Maloney murine leukemia virus 29:127 (MMuLV) inhibition by 29:127 Malonomicin 28:118 antiprotozoal activity of 28:118 Maltophilin 28:140 as antifungal agent 28:140 (-)-Malyngolide 19:463 antimicrobial activity of 19:492 Mam-2 assay system 29:87 3 ~-acetoxy- 8 ~-isobutyrylo xyreynosin activity in 29:87 Mammalian cell 30:592 carcinogenesis in 30:592 Mammalian cell mutation test 27:304 Mammalian lipoxygenases 30:225 Mammalian toxicity 21:1 O0 Mammary carcinoma 1:275 Mange mites 28:409 transmission of 28:409 treatment of 28:409 Mangicol A 29:111 activity in TPA bioassay system 29:111 Mangicol B 29:111 activity in TPA bioassay system 29:111 c~-Mangostin (prenylated xanthone) 29:573 effects on HIV- 1 protease 29:573 ?-Mangostin (prenylated xanthone) 29:573 effects on HIV-1 protease 29:573 Maniladiol (olean- 12-ene-313,16[3diol) 29:587 effects on CHY 29:587 Maniladiol 3-O-myristate (Olean- 12ene-3[3,1613-diol 3-O-myristate) 29:587 effects on CHY 29:587 Mannosidase 19:356 inhibitor of 19:356 mannojirimycin inhibition by 7:41 c~-Mannosidase inhibitor synthesis of 1:331
1151
Mannostatins A & B 10:523,524 a,D-mannosidase inhibitors 10:523 Manoalide 3:157,158;18:717;29:111 activity in PLA bioassay system 29:111 antibacterial activity of 16:666 inflammatory activity of 16:666 inhibitory activity of 16:666 13-epi Manoyl oxide 29:102 activity in EBV bioassay system 29:102 Manoyl oxide F1 29:102 activity in PLA bioassay system 29:102 Manumycins 24:435-437 inhibitors of FPTase 24:435 MAO A 30:377,382 deamination of dopamine by 30:377 deamination of serotonin by 30:377 deamination of noradrenaline by 30:377 in fetal brain 30:377 MAO B 30:377 deamination of dopamine by 30:377 deamination of benzylamine by 30:378 deamination of neurotransmitters by 30:378 deamination of phenylethylamine by 30:378 in adult brain 30:378 MAO blocker MAO inhibitors 21:84,101 MAOA gene 30:380,382 aggressive behavior of 30:380 in knockout mice 30:380 Marcfortine A (MFA) 28:331,332, 336,372 antiparasitic activity of 28:332 Margaritaria discoidea 28:395,406 acaricidal activity of 28:406 acaricidal properties of 28:395 Marine alkaloids 29:426 cytotoxic activity of 29:426
Marine fungi 24:981,1005,1006,1048, 1049,1051-1055,1078-1081,10841086 anti-bacterial substances of 24:1049,1051,1084 anti-fungal substances of 24:1049,1052,1053 anti-malarial substances of 24:1055 anti-microalgal substances of 24:1055,1084 anti-microbial substances of 24:1049,1054,1084 anti-parasitic substances of 24:1049,1084 anti-viral substances of 24:1053 pharmacological aspects of 24:1048,1049,1084-1086 toxicological aspects of 24:1048, 1049,1084-1086 Marine invertebrates 9:493-495 neuropeptide from 9:493-495 Marine lymphoma 23:187 cytotoxicity against 23:187 Marine macrolide 19:549 antifungal activity of 19:549 antitumor activity of 19:549 antiviral activity of 19:549 bioactive 19:549-626 cytotoxic activity of 19:549 immunomodulatory activity of 19:549 Marine-derived 24:526-543 as antiviral compound 24:526543 Marmesin 28:18 antifungal activity of 28:18 Maslinic acid (triterpene) 29:575 effects on HIV- 1 protease 29:575 Mast cells 27:806;30:367,370 activity of tryptophan hydroxylase (TPH) in 30:370 Matairesinol 26:217 inhibitory activity of 26:217 Maternal thalidomide 30:374 autistic features in 30:374 a-Mating factor pheromone 25:387
1152 Matrigel-implanted angiogenesis assay 30:62 activity of triterpenoid fractions in 30:62 Matrigel-induced angiogenesis 30:67,69 effect of oleic acid on 30:69 in vitro 30:67 in vivo 30:67,69 (+)-Matrine 30:205 activation of kappa-opioid receptor by 30:205 activity in acid-induced abdominal contraction test 30:205 antinociceptive effect of 30:205 Matrine 30:205 structure-activity relationship of 30:205 Mattucinol-7-O-[4",6"-O-(S)-hexahydroxy-diphenoyl]-~-D-glucopyranoside (polyphenol glycoside) 29:571 inhibition of Candida albicans by 29:571 pepsin inhibition by 29:571 Maturation 30:378 serotonin action on 30:378 Maximal Electroshock Test (MEST) 22:508 Maytenus aquifolium 30:639 cyclase activity of 30:639 Maytenus species 30:693 against Candida albicans 30:693 against gram-negative bacteria 30:693 against gram-positive bacteria 30:693 Measles 30:408 immunization against 30:408 Measles virus (MV) 26:223;30:408,412 Measles virus (MV) replication 30:408 inhibitor of 30:408 Mechanism 30:368 of serotonin (5-HT) re-uptake inhibitors 30:368 MECP2 gene 30:373 in Rett's disorder (RTT) 30:373 mutation in 30:373
Median antinocieptive dose (EDs0) 30:802 Medicagenic acid glycoside 21:661 Medicarpin 28:229 biological activity of 28:229 Medicinal plants 24:877,878;30:55 chronic inflammation alleviation by 24:887-895 effect on neuromuscular synapse 24:877,878 for allergic inflammation 30:55 for arteriosclerosis 30:55 for cancer 30:55 for coronary artery constriction 30:55 for coronary heart diseases 30:55 for diabetes 30:55 for hypertension 30:55 for thrombosis 30:55 for tumor metastasis 30:55 for tumors 30:55 Medicinal use 27:445 of Astragalus root 27:445 of Astragalus seeds 27:445 Mediterranean fever 30:194 use of A6-tetrahydrocannabinol (THC) 30:194 Megaphone acetate 26:212 cytotoxicity of 26:212 MEL-28 (human melanoma) 30:691 phenolic triterpenes against 30:691 Melanin formation assay 21:589 Melanine pigment 16:615 physiological role of 16:615 Melanogenesis 26:965 Melanoma 1:275;21:634 B 16-BL-6-Melanoma 21:638 Melanoma cells 16:90;21:590 Melatonin 30:369 synthesis of 30:369 role in circadian rhythmicity 30:369 Melia azedarach 26:187 phag-inhibitory activity of 26:187 Meliacin 24:524 as antiviral glycopeptide 24:524 Membrane electric potential 21:8
1153 Memory improvement 23:499 Bacopa monniea in 23:499 Meningitis 2:422 due to Candida neoformans 2:422 Menorrhagia 22:643 Mental disorders 30:368 role ofserotonin (5-HT) 30:368 p-Menth- 1-ene 29:83 activity in AM assay system 29:83 activity in lung-1 assay system 29:83 p-Mentha-2,8-dien- 1-ol 29:83 activity in GST assay system 29:83 Menthol 29:83;30:193,207 activity in AM assay system 29:83 activity in Mam-2 assay system 29:83 analgesic properties of 30:207 kappa-opioid receptor activation by 30:207 (-)-Menthol 30:207 activity in abdominal constriction test 30:207 activity in hot-plate test 30:207 antinociceptive effect of 30:207 (-)-Menthone 29:83 activity in AM assay system 29:83 6-Mercaptopurin 25:266 Meretrix petechialis 30:400 Merkel cell carcinoma 30:308 aloe-emodin effects on 30:308 Merozoite stage 25:328,329 (+)-Mesquitol (3,7,3',4'-tetrahydroxyflavan) 29:580 effects on ACE 9 29:580 Metabotropic glutamate receptors 25:531 Metal homeotasis 25:327 Metalloproteases 29:569 in angiogenesis 29:570 in embryogenesis 29:570 in inflammation 29:570 in tumor growth 29:570
in wound healing 29:570 tissue inhibitors of 29:570 Metallo-proteases 30:836 ot2-macroglobulin inhibition by 30:836 Metamorphosis 21:366;25:784 Metastasis 19:351 ;30:64 in liver 30:64 in mice 30:64 of tumors 19:351 Metastatic cells 16:76 Metastatic secondary tumor 26:221 in animals 26:221 Metastatic tumor cells 30:60,61 in liver 30:60 Metastatic tumor growth 30:69 in liver 30:69 Metastatic tumors 30:64 in LLC-bearing mice 30:64 inhibition of 30:64 Metatrichia vesparium 29:232 antibiotic properties of 29:232 Meth 1 tumor cells 25:432 Meth A fibrosarcoma 28:534 antitumoral effects of 28:534 Meth A tumor 25:432 Meth A tumor cell antigen 25:444 cytotstatic activity of 25:433,434 Meth A tumor growth 25:453 12-Methoxyabieta-8,11,13-trien- 11-ol 29:99 activity in EBV assay system 29:99 24S)-25-(M ethoxy-c yc 1o artane dio 1 ( 24S)-25-methoxyc yc lo artane3 p,24-diol) 29:587 effects on TRY 29:587 5-Methoxydehydrodiisoeugenol 26:226 antibacterial activity of 26:226 5-Methoxydehydropodophyllotoxin 26:212 cytotoxicity of 26:212 1-Methoxyficifolinol 28:229 biological activity of 28:229 1-Methoxymiller-9Z-enolide 29:89 activity in NFkB assay system 29:89
1154 1-Methoxyphaseollidin 28:243 anti-Helicobacter pylori activity of 28:243 biological activity of 28:229 Methyl 12,13-epoxy-trans-communate 29:101 activity in EBV bioassay system 29:101 Methyl 15,16-bisnor- 13-oxolabda-8(17), 11E-dien-19-oate 29:101 activity in EBV bioassay system 29:101 Methyl 15-hydroxy-7-oxo-dehydroabietate 29:99 activity in EBV assay system 29:99 Methyl 15-hydroxy-8,12cx-epidioxyabiet- 13-en- 18-oate 29:99 activity in EBV assay system 29:99 Methyl 15-hydroxy-8cx, 14Gt,12cx, 13cx-diepoxyabietan- 18-oate 29:99 activity in 29:99 Methyl 6c~,7cx-dihydroxyvouacapan17~-oate 29:103 activity in AOS bioassay system 29:103 Methyl aplysinopsin 5:410 antidepressant activity 5:410 Methyl dehydroabietate 29:99 activity in EBV assay system 29:99 Methyl ent- 13-hydroxykaur- 15-en- 19oate 29:101 activity in EBV bioassay system 29:101 Methyl epijasmonate 6:558-559,8:152155 plant growth inhibitor 8:140 N-Methyl isocorydine 24:856 neuromuscular blocking action of 24:856 Methyl ketones 29:366 anti-angiogenic properties of 29:369 as tubulin polymerization inhibitor 29:366
effects on tumor vasculature 29:366 Methyl labda-8(17), 13-dien- 15,12Rolid- 19-oate 29:101 activity in EBV bioassay system 29:101 Methyl salicylate 28:406 acaricidal properties of 28:406 Methyl salicylate 28:406 acaricidal property of 28:406 1-Methyl-4-phenyl-l,2,3,6-tetrahydropyridine (MPTP) 28:184 dopaminergic neurotoxicity of 28:184 Methylcholanthrene-induced fibroscoma 25:432 N-Methyl-D-aspartate (NMDA) receptors 28:184 EGb as antagonist of 28:184 radioligand binding of 28:184 24-Methylenecycloartenol (24methyl-cycloart-24 (24')-en-3 [3-ol) 29:587 effects on CHY 29:587 (-)-Methylenolactocin 16:699 antitutmor antibiotic 16:699 3-O-Methylgancaonin P 28:229 biological activity of 28:229 4'-O-Methylglabridin 28:229 biological activity of 28:229 3-O-Methylglycyrol 28:224 anti-microbial activity of 28:224 anti-Helicobacter pylori activity of 28:243 2-Methylheptadecane 19:125 pheromone of 19:125 N-Methylhernangerine 30:565,594 as platelet aggregation inhibitor 30:594 (+)-N-Methylhernangerine 30:590 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:589 Methylmalonyl CoA 11:194,195 with macrolide antibiotic 11:195
1155 N-Methyl-N-nitrosourea (NMU) 29:76 induced colon tumors 29:76 7-con-O-Methylnogarol 14:47,78,79 antitumor activity of 14:48 3-O-Methylnordihydroguaiaretic acid 24:742 anti-HIV activity of 24:742 N-Methylovigerine 30:590 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:589 13-Methylpentadecanoic acid 26:64 antimicrobial activity of 26:64 Methylpiperbetol 26:243 as PAF-induced inhibitor 26:243 7-0 Methylrosmanol (abietane diterpene) 29:575 effects on HIV- 1 protease 29:575 2'-N-Methyl-tetrandinium chloride (bisbenzylisoquinoline) 29:578 effects on ACE 29:578 Mevastatin 21:212 (+)-Mevinolin 11:335,336 biological activity of 11:335, 336 reductase inhibitor of 11:335, 336 Mexicanin I 29:90 activity in NFkB assay system 29:90 Mice 30:27 antitumor activity in 30:27 Microbial secondary metabolites 15:439-463 screening of oncogene function inhibitor from 15:439-463 Microbial transformation 23:34 of SAM 23:21,29,34,41 Microbicidal compound 30:406 against sexually-transmitted disease agents 30:406 Microbiological evaluation 30:739 Microbiostatic inhibitory activity 26:402 Micrococcus luteus 30:693,738 antifungal activities against
30:738 minimal inhibitory concentration (MIC) of 30:693 Microculture tetrazolium (MTT) assay 21:262 Micronucleus test 27:303 Microorganisms 30:738 chemical defense against 30:738 Microspinsodamide 28:680 in HIV-1 infection 28:681 Microtubule stabilizing agents 30:5 discodermolide as 30:5 epothilone as 30:5 eleutherobin as 30:5 laulimalide as 30:5 taxol as 30:5 Microxine 28:691 as Cdc2 kinase inhibitor 28:691 effects on solid tumours 28:145 Migraine 30:194,206,367,368 role ofserotonin (5-HT) 30:367, 368 use of Tanacetum parthenium in 30:206 treatment of 30:206 use of A6-tetrahydrocannabinol (THC) 30:194 Mildiomycin 4:241, activity of 4:245 Miller-9E-enolide 29:89 activity in NFkB assay system 29:89 Miltirone 29:212 antioxidant behavior of 29:212 biological activity of 29:212 Mimosamycin 25:825 Minimal inhibitory concentration (MIC) 30:693 of Bacillus subtilis 30:693 of Bacillus pumilus 30:693 ofMicrococcus luteus 30:693 of Staphyllococcus aureus 30:693 of Staphyllococcus epidermidis 30:693 of Staphyllococcus saprophyticus 30:693 of Staphyllococcus warnieri 30:693
1156 Miosin light-chain kinase 27:858 Miotic agent 21:750 Misoprostot 25:616 Mithramycin 24:547 antiviral microbial-derived compound 24:547 Miticidal properties 28:390,414 of Azadirachta indica 28:414 of estragole 28:414 of eugenol 28:414 of linalyl acetate 28:414 of menthol 28:390 of terpenes 28:414 Mitogen-activated protein kinase (MAPK) 25:522,547 Mitogenesis 30:4 induction by concanavalin A 30:4 Mitogenic effect study 27:798 Mitogenicity 28:530 of lipid A 28:530 to B lymphocytes 28:530 Mitogen-induced arctigenin 26:217 inhibitory activity of 26:217 Mitogen-induced mouse splenocyte proliferation 25:271 Mitomycin 1:340;4:573;5:439,440; 16:573;28:559 as anticancer drug 28:559 Mitomycin A 13:434,435,445-447,460, 467 Mitomycin B 13:439 Mitomycin C 21:137,264 ;25:268;30:691 against hepatoma (HEPA-2B) 30:691 against nasopharynx carcinoma (KB, ED) 691 Mitomycin-based prodrug 21:160 Mitomycin-resistant tumors 21:264 Mitotic activity 2:380;21:751 of the cells 2:380 Mixed inhibitors 7:40 MMTP 26:1091,1092 antimicrobial activity of 26:1091,1092 MMTP 26:1099 antimicrobial activity of 26:1099 MNU inuduced mammary tumors 25:46
Moderate depression 30:603 treatment of 30:603 Mokkolactone 29:89 activity in EBV assay system 29:89 Molluscicidal activity 21:591,596,660; 22:614 ;24:799;28:59;30:153,332,333 as biological activity 24:799 of bergapten 23:357 ofLicania carii 28:60 of Licania densiflora 28:60 of Licania heteromorpha var. heteromorpha 28:60 ofLicania licaniaeflora 28:60 ofLicania pittieri 28:60 ofLicania pyrifolia 28:60 of lapachol 30:333 of natural naphthoquinones 30:332 Molluscicide 7:425-427 Moloney sarcoma virus 5:565 Monoamine neurotransmitters 30:627 adhyperforin inhibitor of 30:627 in behavioral models 30:627 Monoamine oxidase (MAO) 30:377,384 effect on dopamine 30:377 effect on noradrenaline 30:377 effect on serotonin 30:377 neurotransmitters degradation by 30:377 Monoamine oxidase activity 25:594 Monoamine-synthesis inhibitor 30:204 inhibition of antinociception by 30:204 Monoclonal antibody (MAO) 464,955 Monoclonal antibody immunoassay CIEIA 24:933,939,941,942 Monoclonal anti-I 10:484 biosynthesis of 10:484 I-antigenic determinant of 10:480,481 Monocyte chemoattractant protein I 25:598 Mononuclear cells (MNCS) 25:462,477 Mononuclear leukocytes 30:370 activity of tryptophan hydroxylase (TPH) in 30:370
1157 Monoterpenes 24:461 ;27:384 activity of 27:384 FPTase inhibition by 24:461 Monoterpenoid enantiomers 27:377 biological activity of 27:377 Monotetrahydrofuranic derivatives 28:437 as complex I inhibitor 28:436, 437 Moracein B 28:230 biological activity of 28:230 Moraceous plants 28:226 anti-HIV flavonoids from 28:226 Moracin C 28:226 anti-human immunodeficiency virus (HIV) activity of 28:226 Moracin C 28:230 biological activity of 28:230 Moracin N 28:18 as aromatase inhibitor 28:18 Morbidity 30:747 in infants 30:747 Morbus Alzheimer 21:19 Morbus Parkinson 21:19 Morin (3,5,7,2',4'-pentahydroxyflavone) 29:573 effects on HIV-1 protease 29:573 effects on ACE 29:580 Morin (flavonol) 29:585 effects on LELA 29:585 effects on MMP 29:582 Morning sickness 30:561,597 treatment of 30:597 use of Hernandia moerenhoutiana in 30:561,597 use of Hernandia nymphaeifolia in 30:561,597 use of Hernandia voyronii in 30:561,597 Morphine 26:820;30:193,195,200,801 as psychodelic drug 26:820 as natural analgesic 30:195 inhibitory effects of 30:801 Morphogenic properties 30:367 of serotonin (5-HT) 30:367 Morus alba 28:200 hypotensive action of 28:200, 209
Morus flavonoids 28:215 effects on arachidonate metabolism 28:215 Morus nigra 30:207 use as anti-inflammatory agent 30:207 use in folk medicine 30:207 Morus species 28:207 anti-hyperglycemic effect of 24:917 bombesin receptor antagonist from 28:221 hypotensive action of 28:207 inhibition of histamine release 24:914-917 Morusin 28:211 ;30:207 anti-human immunodeficiency virus (HIV) activity of 28:226 antinocicieptive effect of 30:207 anti-tumor activity of 28:211 biological activity of 28:212,230 Morusinol 28:230 biological activity of 28:230 Mosquitocidal 24:864 bioassay of 24:864 Mosquitocidal activity 24:860 Mouse fail-flick assay 30:815 in vivo 30:815 Mouse mammary organ culture assay 30:593 activity of cancer hemopreventive agent 30:593 Mouse mammary organ culture model 30:591 chemopreventive activity in 30:591 Mouse skin carcinogenesis test 30:593 activity of cancer chemopreventive agent 30:593 Mouse vas deferens (MVD) 30:810 activity in receptor binding assay 30:810 mrTNF-a-induced hepatic apoptosis 25:468 MSR inhibition 23:180 of sesquiterpenes 23:180 MsTI as 29:598 PFSI as 29:598 PsTI-I, PsTI-II, PsTI-III, PsTI-
1158 IVA, PsTI-IVB, PsTI-V as 29:599 PVI-3 as 29:598 PVI-4 as 29:599 SBI-1 as 29:598 SBI-2 as 29:598 SBI-3 as 29:598 TaTI as 29:599 TcTI as 29:599 TI-II/TI-II' as 29:599 VAI as 29:599 MTBI 26:1091,1092 antimicrobial activity of 26:1091,1092 MTT assay 21:149 Mu receptors 22:24 Mucocutaneous leishmaniasis 30:742 by Leishmania braziliensis 30:742 Mucor mucedo 30:739 antibacterial activity against 30:739 antifungal activity against 30:739 Mucositis 21:158 Mukaiyama aldol reaction 30:17,42,43 Mulberrin 28:230 biological activity of 28:230 Mulberrochromene 28:230 biological activity of 28:230 Mulberrofuran B 28:230 biological activity of 28:230 Mulberrofuran C 28:209 hypotensive action of 28:209 Mulberrofuran F 28:209 hypotensive action of 28:209 Mulberrofuran G 28:209 hypotensive action of 28:209 Mulberrofuran G 28:212,230 biological activity of 28:212,230 Mulberry tree 28:225 anti-human immunodeficiency virus (HIV) activity of 28:226 Multi-drug resistant cancers 30:5 chemotherapeutic agent for 30:5 clinical development for 30:5 Multidrug-resistant human cancer cell 12:390
staurosporine activity against 12:390 Multinucleate syncytia 30:397 Multireference Moller-Plesset theory 30:542 application of 30:542 Murine acquired immunodeficiency syndrome (MAIDS) 25:433 Murine cancer cell lines 30:589,590 activity of (-)-deoxypodo phyllotoxin in 30:589 activity of (-)-hernone in 30:590 activity of (-)-nymphone in 30:590 activity of (-)-yatein in 30:590 activity of (+)-corytuberine in 30:589 activity of (+)-epiaschantin in 30:590 activity of (+)-epimagnolin in 30:590 activity of (+)-epiyangambin in 30:590 activity of (+)-hernovine in 30:589 activity of (+)-laurotetanine in 30:589 activity of (+)-magnoflorine in 30:589 activity of (+)-malekulatine in 30:590 activity of (+)-N-hydroxyhemangerine in 30:589 activity of (+)-N- formylnornantenine in 30:589 activity of (+)-N-formyldehydroovigerine in 30:589 activity of (+)-N-formylovigerine in 30:589 activity of (+)-ovigerine in 30:590 activity of (+)-ovihernangerine in 30:590 activity of (+)-vateamine-2' [3-Noxide in 30:590 activity of 7-formyldehydrohernangerine in 30:589 activity of 7-formyldehydronornantenine in 30:589
1159 activity of 7-formyldehydroovigerine in 30:589 activity of 7-hydroxy-6-methoxy1-methylisoquinoline in 30:589 activity of 7-oxohernagine in 30:590 activity of demethylsonodione in 30:589 activity of hernandonine in 30:589 activity of hernanymphine in 30:589 activity of N-hydroxyovigerine in 30:589 activity of N-methylcorydaldine in 30:589 activity of N-methylovigerine in 30:590 activity of thalifoline in 30:590 Murine cytomegalovirus (MCMV) 26:223 Murine leukemia virus LP-BM5 MuL V 30:768 cause of immunodeficiency syndrome 30:768 Murine lymphocytic leukemia 24:57-60, 69,89 Murine lymphomas L 26:1200,1210 Murine tumor cell replication 23:177 bipinnatins effect on 23:177 Musca bioassay 29:25 2,3-bis(trimethylsilyl) 22,25dideoxyecdysone activity in 29:27 canescensterone activity in 29:28 capitasterone activity in 29:27 cyasterone activity in 29:27 22,25-dideoxy-6(c~/13)-hydroxyecdysone activity in 29:27 ( 25 R/S)20,26-dihydroxyecdysone
activity in 29:27 20-hydroxyecdysone 22-acetate activity in 29:28 20-hydroxyecdysone 22-0(pyrrole-2-carboxylate) activity in 29:28 20-hydroxyecdysone 22-0(thiophene-2-carboxylate) activity in 29:28
20-hydroxyecdysone 22-0chloroacetate activity in 29:28 20-hydroxyecdysone 22-0glycolate activity in 29:28 20-hydroxyecdysone 2-Ocinnamate activity in 29:27 3 -ep i- 2 0-h ydro x y-ecd yso ne
activity in 29:27 20-hydroxyecdysone activity in 29:27 makisterone C activity in 27 3 f3-methoxy-2 f3,14c~-dihydroxy513- cholest-7-en-6-one activity in 29:27 22-O-methyl-20-hydroxyec-
dysone activity in 29:28 pinnatasterone activity in 29:28 polypodine B 2-O-cinnamate activity in 29:27 27-nor-213,313,14c~-trihydroxy- 513cholest-7-en-6-one activity in 29:28 2 f3,3f3,14o~-trihydroxy-5f3cholest7en-6-one 2,3-acetonide activity in 29:28 213,3~3,14c~-tris(trimethylsilyloxy) -5 ~3-cholest-7-en-6-one activity in 29:27 using Musca domestica larvae in 29:25 Muscarinic acetylcholine receptor 21:52,90 Muscarinic AchR antagonists 21:56 Muscarinic antagonist 22:19 Muscarinic receptor 21:95;22:18; 25:530,611 Muscarinic receptor antagonists 22:734 Muscarinic-l,2-receptor 21:95 Muscle pain 24:898 aconitine for relieving 24:898 Musclide-A1 24:906-908 activation effects of 24:906 medicinal uses of 24:906 protein kinase C activation effects 24:906 Muscular activity 21:102
1160 Mustard (Brassicaceae) trypsin inhibitors 29:612 ATTI-1 as 29:612 ATTI-A, ATTI-A', ATTI-B, ATTI-C, ATTI-D as 29:612 effects on chymotrypsin 29:612 effects on trypsin 29:612 from Arabidopsis thaliana 29:612 from Brassica napus 29:612 from Brassica oleraceae 29:612 from Sinapis alba 29:612 MTI-2 as 29:612 RTI as 29:612 RTI-IIIA as 29:612 RTI-IIIC as 29:612 thrombin inhibitor as 29:612 Mustard-based prodrug 21:160 Mutagenesis 30:174 induction by xenobiotics 30:174 Mutagenic action 27:304 of human lymphocytes 27:304 Mutagenic activity 5:447;22:614;26: 675;30:750 of estrogen 5:447 of fumonisins 13:532 ofRubia tinctorum 26:675 in Ames test 30:750 Mutagenicity 7:9;22:623 Mutagenicity tests 27:303,304 Ames test 27:303 chromosome mutation test 27:303,304 for stevioside 27:303,304 forward mutation test 27:303 mammalian cell mutation test 27:304 micronucleus test 27:303 Mutagen-induced genetic variation 25:395 Mutagens 24:1061,1062 Mutation 30:377 in autistic children 30:377 Mutation inhibition activity 21:641 MVD assay 30:801 in vitro model 30:801 6 opioid activity in 30:801 MVD bioassay 30:807,818 [Tic2]deltorphin C activity in
30:807 activity of [Tic2]deltorphin C in 30:818 in vitro 30:807,818 Myasthenia gravis 26:486 Mycale sp. 28:712 as cytotoxic glutathione adducts 28:712 Mycobacterium leprae 30:119 leprosols from 30:119 resorcinolic lipids derivatives from 30:119 Mycoparasitism 21:223 Mycophenolic acid 24:549 antiviral microbial-derived compound 24:549 Mycothiazole 28:710 anthelmintic properties of 28:710 Mycotoxicity 21:410 Mycotoxin 21:240 Myeloid leukemia cells differentiation 30:498 effect of 1(x,25-dihydroxyvitamin D3 30:498 Myelotoxicity 27:436;28:559 by doxorubicin 28:562 of chitosan 28:559 of fish oils 28:559 Myelotoxicity of 5-FU 28:561 chitosan inhibitory effect on 28:561 Mylosuppression 25:447,448 effect of 5-fluorouracil 25:447, 448 Myocardial infaction 25:598 Myocardial ischaemia 25:594;26:233 Myoclonic seizures 22:508 Myricetin (3,5,7,3',4',5'-hexahydroxyflavone) 29:573 effects on aminopeptidase N 29:577 effects on ACE 29:580 effects on HIV-1 protease 29:573 effects on NEP 29:581 Myricetin (flavonol) 29:582 effects on HIV- 1 protease 29:573
1161 effects on LELA 29:585 effects on MMP 29:582 Myxovirus 30:408 inhibitor of 30:408 Na-+,K+ ATPase inhibitor 25:535 Na+/Ca 2+ antiporters 25:517 Na+/K+-transporting adenosine triphosphate (ATP)ase inhibitor 28:670 from Agelas nakamurai 28:670 Na+C1--linked monoamine neurotransmitter transporter 25:537 NAD (P)-O2-oxidoreductase activity 25:811 NADDP receptor Ca 2+ channels 25:539 NADDP receptors 25:534 NADH-dependent keto-reducing activity 25:500 Nagilactone A 28:480 anti-feedant activity of 28:480 Nagilactone C 28:475 anti-fungal activity of 28:475 Nagilactone C 28:480 anti-feedant activity of 28:480 Nagilactone E 28:475 anti-fungal activity of 28:475 Nantrindole 30:803,804,806 antinociceptive action of 30:816 as 6-opioid receptor antagonist 30:803 blockade of 8-opioid receptors by 30:802 effects of 30:804 Naphthaleneacetic acid 7:90,94 as auxin 7:90,94 Naphthocyanidine 10:106 antitumor activity of 10:104 Naphthoquinones 4:388,389;7:435; 28:408,429;29:747,750 action of 28:429 analgesic effects of 29:725 antiamoebic effects of 29:725 antibacterial effects of 29:723 antifungal effects of 29:723,725 antiinflammatory effects of 29:725 antipyretic effects of 29:725
antithrombotic effects of 29:725 antitumor effects of 29:723,729 apoptosis induced by 29:727 biological properties of 29:723 biosynthesis of 2:226 chemopreventive effects of 29:725,728 cytotoxic effects of 29:723 dehydrodunnione as 29:733 leishmanicidal effects of 29:723 mechanism of action of 29:747 mitochondrial respiration inhibition 28:by 28:429 topoisomerase inhibition by 29:727 trypanocidal effects of 29:723 wound healing effects of 29:725 against human rhinoviruses (HRVs) 29:750 antipsoriatic activity of 29:751 antiviral 29:750 immunostimulating properties of 29:751 insecticidal activity of 29:751 larvicidal activity of 29:751 molluscicidal activity of 29:751 synthesis of 3:450,451 toxicity of 29:751 with isovaleraldehyde 4:396,398 Naphthoquinones, antiparasitic 29:747 against Trypanosoma cruzi 29:748 as antileishmanial agents 29:747 as antimalarial drugs 29:747 as TcTR inhibitors 29:748 as trypanocidal agents 29:747 Naphthoquinones, leishmanicidal activity 29:749 against Leishmania braziliensis 29:749 against Leishmania donovani 29:749 against Leishmania enriettii 29:749 against Leishmania injhntum 29:749 against Leishmania major 29:749
1162 Naphthyridinomycin 10:108-115 antitumor activity of 10:107 Naphtooxirene derivatives 7:407 antifungal activity of 7:407 cytotoxicity of 7:407 Naproxene 14:505 antiinflammatory drug 14:505 Narburgia stuhlmanni 1:701,702 antifeedant from 1:701,702 Narcotic analgesic effect 30:200 Narcotic opiate alkaloid 30:804 (2S)-Naringenin 28:17 aromatase inhibition by 28:17 Naringenin 28:229 biological activity of 28:229 Naringenin (5,7,4'-trihydroxy flavanone) 29:580 effects on ACE 29:580 Naringin (2,3-dihydroapigenin 7-0rhamnosyl-glucoside) 29:573 effects on HIV- 1 protease 29:573 Naringin (naringenin-7- O-(2'-Orhamnosyl)glucoside) 29:580 effects on ACE 29:580 13-Narin-II8-4'-Ome-eridictyol 30:207 activity in formalin test 30:207 activity in writhing test 30:207 Natriuretic effect 26:269 Natural analgesic products 30:195 capsaicin as 30:195 Ag-tetrahydrocannabinol as 30:195 morphine as 30:195 Natural anthracyclines 21:157 for antibody directed enzyme prodrug therapy 21:157 for prodrug monotherapy 21:157 prodrugs of 21:157 Natural antifungals 23:340 activation of 23:129 animal sources of 23:340 fungal sources 23:347 natural killer (NK) 23:129 plant sources 23:346 prokaryotic sources 23:349 structure of 23:340
Natural bridged biaryls 29:355 antimitotic properties of 29:355 as anticancer compounds 29:355 effects on cell division 29:355 interaction with tubulin 29:355 Natural flavonol 30:224 antioxidant properties of 30:224 kaemferol from 30:224 Natural fungicides 21:181 Natural inhibitors 20:889;27:836 of carcinogenesis 30:591 ofphosphatases 20:889 of protein kinases 27:836 Natural killer cells (NK cells) 25:273 Natural oligopeptides 27:793 with biological activities 27:793 Natural phytotoxins 26:369 Natural podolactones 28:484 allelopathic activity of 28:484 Natural polyphenols 30:226 activity in biochemical assays 30:226 effect on HIV- 1 integrase inhibition 30:226 Natural product inhibitors 24:418-442 competitive with FPP 24:418-438 competitive with Ras peptide 24:438-442 farnesyl-protein transferase as 24:403-464 non-competitive 24:442-462 Natural product libraries 29:646 of drug metabolites 29:668 of drugs 29:668 of herbicides 29:668 of novel pharmaceuticals 29:650 oftyrosinase inhibitors 29:667 Natural products 24:351-398,473555;27:398;28:573,617;29:643; 30:55,79,191,219,703,738 anti-metastatic activity of 28:559,573 anti-obesity action of 27:398 anti-psychotic activity of 24:1116 as antiviral agents 24:473-555 anti-tumor activity of 28:559 antitumor effect of 30:55,56
1163 anti-tumor-promoting activity 24:215-264 as analgesics 30:191 as anti-hypotensive drugs 29:643 as anti-inflammatory drugs 29:643 as anti-obesity materials 30:79 as antiulcer drugs 29:643 as bioactive compounds 24:473,475 as cyclooxygenase enzyme 29:645 as lipoxygenase enzyme 29:645 as platelet aggregation inhibitors 29:653 biological activity of 27:393,405 defensive role of 30:738 effects of 30:79 from medicinal plants 27:393; 29:643 from plants 30:703 in allergic inflammation 30:55 in arteriosclerosis 30:55 in cancer 30:55 in coronary heart diseases 30:55 in diabetes 30:55 m heart diseases 30:55 m hypertension 30:55 in thrombosis 30:55 in tumor metastasis 30:55 m tumor-bearing mice 28:573 medicinal aspects of 24:351-398 pharmacological studies of 27:393 use of 30:191 vascular physiological effect of 30:55 Natural regulation 13:257-261 of gene expression 13:257-261 by antisense RNA 13:257-261 Natural therapeutic herb 30:194 as analgesic 30:194 Naturally occurring protein kinase activators 27:829 NCI assay 18:878 N-containing compounds 24:527-533 as antiviral compound 24:527533 NDGA compound 27:692
Necrosis 26:993;27:87 in mammalians 27:87 Necrotizing agent 25:613,615 Nematocidal activity 12:396;23:840 against Bursaphelenchus lignicolus 12:396;23:840 Nematocidal activity 26:439,443,451, 454,461,466,469,470,474,482, 485,887;28:146 of eliamid 28:146 of fatty acids 26:434 of 2-desoxo- 15 c~-methyl- 14cthydroxy-MFA 28:347 of 2-desoxoparaherquamide A 28:331 Nematodes 1:435 activity against 1:435 Nematostatic activity 26:429,430 Nenrasapora crassa 25:304 ergosterol mutants of 25:304 Neoandrographolide (andrographolide O-glucoside) 29:587 effects on proprotein convertase 29:587 Neojusticin A 26:243 as PAF-induced inhibitor 26:243 Neolaulimalide 19:569 cytoxicity of 19:569 Neolignans 24:739,740,845,847,849, 888-890 anti-tumor activity o f 24: 845, 847,849 chronic inflammation alleviation by 24:887-895 Neomycin 25:925,928 Neopetasin 29:87 activity in PLA assay system 29:87 activity in 5LOX assay system 29:87 Neoplastic activity 26:452;27:306 of stevioside 27:306 Neoplastic B cells 25:270 Neoplastic cell lines 26:752 Neoplastic transformation 5:448 of subclone A-31-1-13 of BALB/c3T3 cells 5:452
1164
Neovacularization 28:572 effect ofegosterol 28:570,572 Neoxanthin 6:133,136,141,146;7:98, 320,321 as ant repellant 6:142 Nephropathy 24:858 Nerium oleander 9:293-315 cyctotoxic agents from 9:293315 Nerol 28:406 acaricidal property of 28:406 Nerolidol 28:406 acaricidal property of 28:406 Nerve growth factor 12:394;26:951; 30:504 effect of K-252a on 12:394 effect of staurosporine on 12:394 role in development of neurons 30:504 Nervine tonic 23:499 bacopa monnira as 23:499 Nervous polyarthritis 26:400 Netropsin 5:575 binding of DNA 5:575 Neural catarrh 26:50 Herniaria hirsuta in 26:50 Neuralgia 30:203 use of ginseng root in 30:203 Neuraminic acid 27:103-152 biological activity of 27:103-152 effects of 27:105,106 Neuraminidase 16:75,93,105,106,107; 27:103,107,108,112-116 enzyme mechanism of 27:114 from viruses 16:108 inhibitor of 16:95,111 of bacteria 16:112 of influenza virus 27:114 target against influenza infection 27:103 Neuraminidase inhibitors 27:130 4-amino-3-nitrobenzoic acid 27:138 4-(N-acetylamino)-3guanidinobenzoic acid 27:138 4-amino-3-hydroxy benzoic acid 27:138,139 calyceramide A as 28:713 I-(4-carboxy-2-(3-pentyl-
amino)phenyl)-5,5-(hydroxymethyl) pyrrolidin-2-one 27:150-152 2-deoxy-2,3-didehydro-Nacetylneuraminic acid 27:130,136 2,3-didehydro-2,4-dideoxy-4guanidyl-Neu5Ac 27:131,135 Neuraticidal 24:866,867 bioassay of 24:866-867 Neurite outgrowth activity 30:505 in hypothalamic neurons of rat 30:505 in neurons 30:505 of dictyosterol 30:505 of natural product 30:505 Neuritis 26:50 Herniaria hirsuta in 26:50 Neuritogenic activity 28:720 of Cucumaria echinata 28:720 Neuroblastoma 26:924,927 cell differentiation of 26:927 Neuroblastoma development 26:754 Neurochemical pathway 30:374 of autistic spectrum disorders 30:374 Neurodegeneration 30:224 role of free radicals in 30:224 Neurodegenerative disease 22:67 Neuroexcitatory activity 26:479 Neurogenic pain 205 induction by formalin 30:205 inhibition by incarvillateine 30:204 Neuroharmonal transmitter 22:15 Neurohormones 27:794 Neurokinin NK~ receptor 30:203 interaction with ginseng 30:203 Neuroleptic drugs 26:270 Neuromuscular activity 21:152 Neuromuscular blocker 24:880-883 effect ofcoclaurine as 24:887 glycyrrhizin as 24:151,880-883 paeoniflorin as 24:878-880 Neuromuscular blocking 24:875 as biological action 24:875 Neuromuscular blocking action 24:875-925
1165 effect of cyclohexylidene on 24:883-887 of Kampo medicines 24:875-926 of N-methyl isocorydine 24:856 Neuromuscular blocking activity 24:851 Neuromuscular blocking effect 24:898-899 of aconite 24:898-899 of hypaconite 24:898-899 Neuromuscular blocks 22:58 Neuromuscular synapse 24:877-887 effect by beta-eudesmol 24:883-887 effect by coclaurine 24:887 effect by cyclohexylidine 24:883-887 effect by glycyrrhizin 24:880883 effect by medicinal plants 24:877-887 effect by paeoxiflorin 24:878880 effect by p-phenylenepolymethylene bis-ammonium 24:883-887 Neuron cell 27:806 Neuronal activity 30:376 in amygdala 30:376 role of human serotonin transporter gene (SLC6A4) in 30:376 Neuronal cell 28:315 crocin's effect on 28:315 Neuronal differentiation 30:368 effect of serotonergic neurotransmission on 30:368 Neuronal excitability 30:194 role of cannabinoids 194 Neuronal functioning 30:378 serotonin action on 30:378 Neuronal signal transduction 21:5 Neurons 30:367 Neuropathological studies 30:376 in autistic brains 30:376 Neuropatic pain syndromes 30:193 use of capsaicin in 30:193 Neuropeptide analogues 27:798 Neuropeptide receptor 25:688
Neuropeptide Y 21:72;27:800 Neuropeptides 9:493-495 from marine invertebrates 9:493495 Neuroprotective properties 28:173,177 of Ginkgo biloba L. 28:173,177 Neuropsychiatric disorders 24:10931134 natural product-derived treatment of 24:1093-1134 Neuroreceptors 21:89 alkaloids with 21:3-111 Neurotensin 27:799,800 Neurotoxic shell 21:300 Neurotoxicity 26:965,1004 HK-Neurotoxicity 26:993 Neurotoxin alkaloids !:385 Neurotoxins 17:3 Neurotransmitter 30:367 serotonin as 30:367 Neurotransmitter antagonists 25:515 Neurotransmitter converting protein 25:512 Neurotransmitter degradation 30:377 by monoamine oxidase (MAO) 30:377 Neurotransmitter receptors 25:512 Neurotransmitter signalling 25:517 Neurotransmitter transporting protein 25:512 Neurotransmitter-gated ion channels 25:519 Neurotransmitters 21:5;22:25;25:516 Neurotrophic activity 23:469;24:854 28:174,177 in neural injury 28:174 of Ginkgo biloba L. 28:177 of Magnolia liliflora 24:854 ofS-alkyl cysteines 23:469 Neurotrophic agents 24:1060 Neurotropic factors (NTFs) 504 in maintenance of nerve cells 30:504 role in survival of nerve cells 30:504 Neutrophiles 22:437 Neutrophils respiratory burst inhibitor 28:16 broussoaurone A as 28:16,17
1166
NF-KB activation 25:470 NF-KB assay system 29:89 3-acetoxycostunolide activity in 29:89 2ot-acetoxy- 14-hydroxy- 15-isovaleroy-loxy-9-oxo-costunolide activity in 29:89 9c~-acetoxy-4[3,15-epoxymiller1(10)Z-enolide 15-Acetoxy-9czhydroxy- 8 [3-methacryl-oyloxy14-oxo-acanthospermolide activity in 29:89 15-acetoxy-9cz-hydroxy-8 [3methacryl-oyloxy- 14-oxoacantho spermolide activity in 29:89 NF-KB Nuclear factor kappa B 25:470,711 NF-KB activation 30:206 effect ofparthenolide 30:206 Nicotianamine 29:578 effects on ACE 29:578 nitrogen compounds 29:328 against Candida genus 29:328 against genus Pseudomonas 29:329 against methicillin-resistant strains 29:331 against Selenastrum capricornutum 29:329 against Staphylococcus aureus 29:331 apoptotic activity of 29:333 cytotoxicity of 29:329 effects on bacteria 29:328 glycopeptide antibiotics as 29:332 herbicide resormycin as 29:329 Nicotinic acetylcholine 21:14,51 Nicotinic acetylcholine receptor 21:51, 90;22:16;25:528 Nicotinic Ach receptor 21:21 Nicotinic acid 21:147 Nicotinic receptor 21:102 Nicotinic toxins 18:697-699 Nigeran 5:299,310 antitumor activity of 5:317
Nitidine 4:544;13:656;14:770;27:159 antileukemic activity of 14:769 biological activity of 27:179 Nitraraine 14:764 biological activity of 14:759 cardiovascular activity 14:764 Nitrate reductases 24:999-1001,1005 enzymatic activity 24:999-1001, 1005 Nitric oxide 26:909,911-914 as mediator of antimmor immune response 26:921-923 as signal in plant defense response 26:937-949 as plant growth regulator 26:934, 935 bioactivity of 26:909,911-914 role in cell apoptosis 26:925,926 role in cell differenciation 26:926 Nitric oxide production inhibitor 28:16 broussoaurone A as 28:16 Nitrobenzene oxidation assays 25:666 Nitrogen sugar inhibitors 7:41-48 Nitrophenyl thiogalactoside 7:48 [~-galactoside inhibition with 7:48 3-Nitropropanoic acid 19:117 biological activity of 19:117 NMDA receptor 21:19,70;22:667 NMDA receptor-mediated responses 25:966 NMDA-induced currents 28:319 in hippocampal neurons 28:319 N-Methyl-D-aspartate binding glutamate receptors 25:529 N-Methyl-N-nitrosurea (MNU) induced colon rumors 25:46 NNK-induced lung tumorigenesis 25:65 NO synthase inhibitor 25:595 Nociceptors 30:191,193 activation of 30:193 in periphery 30:193 Nocturnal epilepsy 22:513,521-522 Cocculus sermentosus for 22:517 Herpestis monniera for 22:513 Flemingia strobilifera for 22:521 Hemidesmus indicus R. for
1167 22:522 Morinaga oleifera for 22:526 Nodularins 9:498,18:269 biological activities of 20:896,897 inhibition of protein phosphatases by 20:903 Nodusmicin activity 17:290 against Staphylococcus aureus 17:290 NOESY experiment 30:582 of (+)-N-formylovigerine 30:582 NOESY interactions 30:587 of (-)-6'-hydroxyyatein 30:587 of (-)-hernone 30:587 Nogalamycin congeners 14:76 antitumor activity of 14:76 Nogalamycines 4:330 synthesis of 4:330 Nojirimycin 6:351;42,50;11:267 glucoamylase inhibitors of 10:525 a-glucosidase inhibitors of 10:526 ~-glucosidase inhibitors of 10:526 glucosidases inhibiton with 7:41 invertase inhibitors of 10:526 takadiastase inhibitors of 10:525 trehalase inhibitors of 10:526 Nojirimycin analogues 7:70 sialidases inhibition by 7:42 Nojirimycin hiptitol derivatives 7:42 (x-glucosidase inhibition with 7:43 NO-mediated apoptosis 26:943 in animals 26:943 NO-modulated transcription factors 26:946 Non-adrenergic imidazoline receptors 25:530 Nonanal 28:406 acaricidal property of 28:406 Non-classical cannabinoids 30:195, 197,198 group of cannabinoid receptor ligands 30:197 Non-cytotoxic prodrugs 21:158
Non-eicosanoid mediators 27:693 Non-enveloped viruses 30:627 adenovirus 30:627 poliovirus 30:627 Non-insulin-dependent diabetes mellitus 25:534 Non-legume,non-cereal Bowman-Birk protease inhibitor homologues 29:600 Ananas BI-I, BI-II, BI-III, BI-IV, BI-V, BI-VI as 29:600 BBI-homologue as 29:600 effects on bromelain 29:600 effects on cathepsin 29:600 effects on cathepsin L 29:600 effects on chymotrypsin 600 effects on cysteine proteases 29:600 effects on elastase 29:600 effects on papain 29:600 effects on thrombin 29:600 effects on trypsin 29:600 fromAnanas comosus 29:600 from Helianthus annuum 29:600 from Solanum tuberosum 29:600 Helianthus BBI SFTI-1 as 29:600 potato BBI as 29:600 Non-NMDA binding glutamate receptors 25:529 Non-NMDA receptors 25:519 Non-protein aspartic protease inhibitors 29:571-575 inhibition of pepsin by 29:571 phenolics as 29:571 terpenes as 29:571 Non-protein cysteine proteases inhibitors 29:575 against common cold (rhinovirus) 29:576 against rheumatoid arthritis 29:576 from Fusarium compactum 29:575 from Hakea gibbosa 29:576 fromSolanum tuberosum 29:593 ginsenoside Rh-2 as 29:576 in clinical trials 29:576 triterpene sulphates as 29:575
1168
Non-protein inhibitors 29:575 against common cold (rhinovirus) 29:576 against rheumatoid arthritis 29:576 from Fusarium compactum 29:575 from Hakea gibbosa 29:576 ginsenoside Rh-2 as 29:576 in clinical trials 29:576 ofcystein proteases 29:575 triterpene sulphates as 29:575 Non-protein metallopeptidase inhibitors 29:577-583 alkaloids as 29:578 from natural sources 29:577 phenolics as 29:577 terpenes as 29:578 Non-protein serine protease inhibitors 29:584-590 from natural sources 29:585 phenolics as 29:584 terpenes as 29:585 Non-small cell lung cancer 23:293 Non-specific DNA damage 26:1004 Non-specific immune response 26:923 Non-specific immunity 24:140-142,146 Non-specific immunomodulators 23:129 Non-steroidal anti-inflammatory drugs (NSAIDs) 25:610;30:192,744,752 clinical use of 30:192 use in dental surgery 30:192 use in headache 30:192 use in osteoarthritis 30:192 use in rheumatism 30:192 Non-sugar fraction 27:409,410 biological activity of 27:409,410 Non-tumorigenic 30:593 JB6 precursor cells as 30:593 NO-participation 26:936,937 in antioxidant cellular systems 26:936,937 Noradrenaline 22:668,669; 30:192,204,377,627,787 as hyperforin inhibitor 30:627 effect of monoamine oxidase (MAO) 30:377 inhibition of hypotensive effect
of 30:787 re-uptake inhibition by DPHD 30:204 Noradrenaline release 30:787 from sympathetic nerve fibers 30:787 Noradrenaline-induced lipolysis 30:83 activation by caffeine 30:83 Norartocarpetin 28:226 anti-human immunodeficiency virus (HIV) activity of 28:226 Norartocarpetin 28:230 biological activity of 28:230 Norepinephrine 22:19;25:516,536, 537,538 Norepinephrine-augmenting lipolytic activity 27:400 ofoolong tea 27:400 NOS inhibitors 25:471 Nothogenia fastigiata 30:403,408 anti-influenza activity of 30:408 xylomannans from 30:403 Novel analgesics 30:206 target of 30:206 Novoimanine 30:628 antimicrobial activity 30:628 NSAIDs (classical) 30:192 effects on COX enzymes 30:192 side effects of 30:192 Nuclear factor kB 25:598 Nuclear sterol regulatory element binding protein nSSREGP 25:388 Nucleating scaffold proteins 25:335 Nucleoside antibiotics 1:397-431 synthesis of 1:397-431 Nucleosides 24:527-533 as antiviral compound 24:527533 Nucleotide-gated ion channels 25:527 Nutrients bioavailability 27:312,314 Nutritional benefits 23:775 of phenolic antioxidants 23:775 (+)-Nyasol 26:230,231 as antiprotozoal agent 26:230 (-)-Nymphone 26:212;30:569,590 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589
1169 cytotoxic effect of 26:212;30:589 OA-antibiotics 4:434 in carbapenem 4:434 Oat carcinoma of lung 1:276 Obesity 27:398;30:79,80,83 gold thioglucose (GTG) in 27:398 model of 27:398 role of oolong tea 30:80 use of orlistat (Ro 18-0647) 30:83 Obsessive compulsive disorder 30:368, 369 effect of circadian activity on 369 role of serotonin (5-HT) 30:368 Occupational asthma 30:337 carmine use for 30:337 Oceanapia sp. 28:713 nematocidal activity of 28:713 [3-Ocimene 28:406 acaricidal properties of 28:406 Odor perception 21:580 Odour substances 27:378 activity of 27:378 OECD and ICH 27:304 ofmutagenesis test 27:304 Oestrogenic activity 28:257,293,302 of natural products 24:215-264 of plant compounds 28:257,302 of Podophyllum extracts 26:169 of polyphenols 28:293 of verrucosin 26:228 OG 25:98,99 antihepatotoxic effect of 25:98,99 antiviral activity of 25:114 OH scavenging activity 22:316 Oidiodendrolide B 28:475 anti-fungal activity of 28:475 Oidiolactone D 28:475 anti-fungal activity of 28:475 Oidiolactones 28:475 antifungal activities of 28:475 Okadaic acid-induced TNF-a-gene expression 25:470
Old world cutaneous leishmaniansis 2:314 cause of 2:312 Oleacein (iridoid monoterpene) 29:581 effects on ACE 29:581 9'-Oleanoglycotoxin-A 7:428 molluscicidal activity of 7:428 Oleanolic acid 2:129,7:134,154,189, 429,430,432,434;9:51,55,57,293; 20:6;30:697,718,719;29:575 antiviral activity of 17:135 effects on HIV- 1 protease 29:575 role in liver disorders 30:637 role in liver injury 30:637 Oleanolic acid-type glucuronides saponins 25:106 hepatoprotective effect of 25:106 Oleficin 28:135 antibiotic activity of 28:135 Oleic acid 30:56,64,65,66,68,69 antitumor activity of 30:56 effect on DNA synthesis in LLC cells 30:68 effect on liver metastatic tumor colonies 30:66 effect on matrigel-induced capillary-like tube network 30:68 effect on spleen weight 30:66 from carp oil 30:65 inhibition of tumor growth by 30:64 inhibitory actions of 30:69 Matrigel-induced angiogenesis (in vivo) 30:69 Oligomeric compound 27:778 biological activity of 27:778 Oligopeptides 24:524;27:793 active against HSV and MV 24:521 antibacterial activities of 27:793804 biological activities of 27:793804 Oligostatins 10:517 amylase inhibitor of 10:516 antibacterial activity of 10:516
1170 mammalian a-amylase inhibitors 10:516 Olive oil 27:697 antiatherosclerotic effect of 27:714 antioxidant activity of 27:710 bioavailability of 27:727 biological activity of 27:714 cardiovascular effect of 27:723 effect on LDL oxidation 27:714, 717,723 effect on platelet aggregation 27:719 effect on reactive oxygeninduced toxicity 27:722 influence ofcultivar on 27:707 prooxidant effects of 27:713 Olong tea 27:400 anti-obesity action of 27:400 OLR-1 30:194 as endogenous peptide opioids 30:193 Olvanil 30:193,202 analgesic action of 30:193 as anti-inflammatory substances 30:201 as capsaicin congener 30:201 as vanilloid receptor agonists 30:202 for analgesia 30:201 phamacological profile of 30:201 role in vasorelaxation 30:201 Onchocerciasis (river blindness) 1:435 treatment of 1:435 Oncogene function inhibitor 15:439-463 from microbial secondary metabolites 15:439-463 screening of 15:463 Oncogene signal inhibitory activity 22:621 Oncogenes 25:545 Oncogenesis 19:351 Oncogenic viruses 15:439 Oncolytic effects 25:460 effect of TNF-a 25:460 OncoVax-P 28:545 against prostate cancer 28:545
Onychine 2:443,443 anticandidal activity of 2:443, 443 Oolong tea 27:401 biological activity of 27:401 Oosponal 24:914-917 inhibition of histamine release 24:914-917 Opiate receptors 21:72;22:24;25:533 Opiates 25:265 as A~ adenosine agonists 25:265 Opioid 30:193,194,799,799,800 as analgesic 30:799 as anti-nociceptive 30:193 in neurotransmitter system 30:799 pharmacodynamics of 30:799 pharmacokinetics of 30:799 physiochemical properties of 30:800 side effects of 30:194 Opioid (8) receptor 25:530 type of G-protein-linked receptor 25:530 Opioid agonist 30:813 Opioid analogues 30:800,813 analgesic potencies of 30:800 development of 30:813 permeation of 30:800 structure activity relationship studies (SAR) of 30:800 ~t-Opioid antagonist 30:813 activity of 30:813 Opioid dipeptide 6-antagonist 30:808 physiochemical properties of 30:809 Opioid drug effects 30:203 of ginsenosides 30:203 inhibition by ginseng extracts 30:203 Opioid interaction 30:807 with ~:-receptors 30:807 Opioid peptides 27:801;30:799,814 biological activity of 27:801 classes of 30:799,814 from Phyllomedusaamphibians 30:799,814
1171 Opioid receptivity 30:808 of ligands 30:808 6-Opioid receptor 30:193,799,802,814 as endogenous peptide opioids 30:193 binding sites of 30:814 blocked by naltrindole 30:802 role in analgesia 30:799 ~t-Opioid receptor 25:530;30:205,801, 802,804,814 activity in guinea-pig ileum bioassay 30:802 affinity of 30:802 binding affinities of 30:205 binding sites of 30:814 in MVD assay 30:801 in vitro bioassay of 30:804 interaction with 30:804 pharmacological bioassay of 30:801 radioligand binding assay of 30:801 type of G-protein-linked receptor 25:530 Opioid receptor affinities 30:814 of glycopeptides 30:814 determination of 30:814 6-Opioid receptor antagonist 30:204, 803,804 H-Dmt-Tic-Ala-OH (DTA) as 30:804 inhibition of antinociception by 30:204 ~-Opioid receptor antagonist 30:204 inhibition of antinociception by 30:204 ~t-Opioid receptor antagonist 30:204 inhibition of antinociception by 30:204 Opioid receptor binding 30:812 ofpentapeptides 30:812 Opioid receptor complex 30:194 8-Opioid receptor ligand 30:817 Opioid receptor subtypes 30:800 delta 1 30:800 delta 2 30:800
Opioid receptors 21:95;22:24;30:200 binding of 30:200 ligands for 30:200 8-Opioid receptors affinity 30:817 in vitro 30:817 pharmacological assay (guineapig ileum) for 30:817 ~t-Opioid receptors affinity 30:817 in vitro 30:817 pharmacological assay (guineapig ileum) for 30:817 Opioid system 30:799 dynorphins in 30:799 endorphins in 30:799 enkephalins in 30:799 in central nervous system (CNS) 30:799 in peripheral tissues 30:799 ligands of 30:799 physiological functions of 30:799 receptor types (~t,6,K) 799 Opioid tripeptide 8-antagonist 30:808 physiochemical properties of 30:809 Opportunistic infections 22:58 Opportunistic Listeria infection 30:773 in immunodeficient mice 30:773 Oral glucose tolerance test 27:409 Orbiculin D 29:88 activity in NFkB assay system 29:88 activity in NO assay system 29:88 Orbiculin H 29:88 activity in NFkB assay system 29:88 activity in NO assay system 29:88 Orbiculin I 29:88 activity in NFkB assay system 29:88 activity in NO assay system 29:88 Oriamide 28:682 as cytotoxic peptide 28:682 Orientin (luteolin-8-C-glucoside) 29:580
1172 effects on ACE 29:580
Origanum syriacum var. bevanii 28:427 acaricidal activity of 28:412 Oripainine 25:533 agonist/antagonist effects 25:533 Ornithine decarboxylase 20:513 by staurosporine 12:393 induction of 12:393 Ornithine decarboxylase (ODC) 25:45,66 role on TPA induced inhibition 25:45 Ornithine decarboxylase inhibition 26:924 Ornithine glucuronides 25:90,103 hepatoprotective activity of 25:90,103 L-Ornithine nitro derivative condensation of 11:437 Orthomycins 29:324 against fungi 29:324 against gram-negative bacteria 29:324 against Neisseria meningitides 29:324 against Staphylococcus aureus 29:324 against Streptococcus pyogenes haemolyticus 29:324 against yeasts 29:324 Orthosiphol A 29:103 activity in TPA bioassay system 29:103 Orthosiphol B 29:103 activity in TPA bioassay system 29:103 Oryza oryzacystatin-I 29:593 effects on papain 29:593 effects on cathepsin H 29:593 Osteoarthritic cartilage 30:318 Osteoarthritis 30:192 use of inflammatory drugs (NSAIDs) 30:192 use of prostaglandin inhibitors 30:192 Osteoarthritis pathophysiology 30:318 interleukin- 113 role in 30:318 Osteoporotic drug 25:711 Ouabain receptor 26:216
Ovarian cancer 24:933 Ovarian cancer treatment 24:933 taxol for 24:933 Ovarian tumor 30:5,27 clinical development for 30:5 chemotherapeutic agent for 30:5 effect of pironetin derivatives in 30:27 inhibitors of tubulin 30:27 (+)-Ovigerine 30:565,590,594 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 as platelet aggregation inhibitor 30:594 cytotoxic effect of 30:589 (+)-Ovihernangerine 30:590 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:589 Oviposition attractant pheromone 3:157-157 Oviposition inhibitor 28:403 dibenzyltrisulfide as 28:403 Oxetanocin A 10:619,620 antiviral activity of 10:619,620 Oxetanocin G 10:586,587 antiviral activity of 10:619,620 Oxidative DNA damage 25:66 3-Oxo-8a-hydroxy- 10c~H-eremo-phila1,7(ll)-dien-12,813-olide 29:87 activity in NO assay system 29:87 2-Oxo-813-methacryloyloxy- 10c~hydroxy-guaia-3,11 ( 13)-dien-6et, 12olide 29:90 activity in NFkB assay system 29:90 2-Oxo-8 [3-methacryloyloxy- 10[3hydroxy-guaia-3,11 ( 13)-dien-6~, 12olide 29:90 activity in NFkB assay system 29:90
1173 2-Oxo-8[3-methacryloyloxy-guaia1( 10),3,11 ( 13)-trien-6c~, 12-olide 29:90 activity in NFkB assay system 29:90 7-Oxohemagine 30:565,590,595 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 as platelet aggregation inhibitor 30:594 cytotoxic effect of 30:589 15-Oxolabda-8(17),11Z, 13E-trien- 19oic acid 29:101 activity in EBV bioassay system 29:101 activity in skin-1 bioassay system 29:101 15-Oxolabda-8(17),11Z, 13Z-trien- 19-oic acid 29:101 activity in EBV bioassay system 29:101 15-nor- 14-Oxolabda-8(17), 12E-dien- 19oic acid 29:101 activity in EBV bioassay system 29:101 15-Oxolabda-8(17), 13Z-dien- 19-oic acid 29:101 activity in EBV bioassay system 29:101 3-Oxotirucalla-7,24-diene-21-oic acid (triterpene) 29:575 effects on HIV- 1 protease 29:575 Oxydihydromorusin 28:230 biological activity of 28:230
P substance 30:193 as pro-nociceptive 30:193 P 13 (phosphatidyl linositol)-kinaseindependent pathway 25:264 P38 leukemia P-388 model 25:823 P-388 (mouse lymphoma) 30:691 phenolic triterpenes against 30:691
P-388 (murine lymphocytic leukemia) 30:588 activity of (-)-deoxypodophyllotoxin against 30:588 activity of (-)-yatein against 30:588 P-388 leukemia cells 21:263,414 P-388 lymphocytic leukemia cell 25:764 P388 mouse leukemia 12:390 staurosperine activity against 12:390 P-388 murine leukemia cells 21:411 Pachyman 5:288,317 antitumor activity of 5:317 Pachyrrhizus erosus 24:779,822-826 anti-feeding activity of 24:825 Pachyrrhizus palmatilobis 24:822 biological activity of 24:823 Paclitaxel 22:33;25:245 Paeoniflorin 24:878-880 as neuromuscular blocker 24:878-880 PAF 30:594 antiplatelet activity of 30:594 PAF antagonist activity 24:740 of 2,6-diaryl-3,7-dioxa bicyclo [3.3.0.] octanes 24:740 PAF antagonists 24:854,1061-1085; 25:275,615 of Magnolia biondii 24:845,854 of Magnoliafarge~'ii 24:854,862 PAF-antagonism 21:134 PAF-induced inhibitors 26:240 (+)-acetoxypinoresinol dimethyl ether as 26:241 arctigenin as 26:241 arctigenin methyl ether as 26:241 chamigrenal as 26:244 cinnamophilin as 26:240 dehydroschisandrol A as 26:245 denudatin as 26:240 (+)-epipinoresinol dimethyl ether as 26:241 epiyangambin as 26:242 fargesin as 26:241 gomisin M as 26:240 honokiol as 26:240
1174 (+)-isogmelinol as 26:241 isogmenolin as 26:241 isoyangambin as 26:242 justicidin B as 26:243 justicidin E as 26:243 kadsurenin H as 26:240 kadsurenone as 26:240 L-653,150 as 26:242 machililin G as 26:242 magnolol as 26:240 magnone A as 26:245 magnone B as 26:245 meso-dihydroguaiaretic acid as 26:240 methylpiperbetol as 26:243 neojusticin A as 26:243 phillygenin as 26:241 (+)-pinoresinol dimethyl ether as 26:241 piperbetol as 26:243 piperol A as 26:243 piperol B as 26:243 pregomisin as 26:244 puberulin A as 26:243,244 puberulin C as 26:243,244 schisandrol A as 26:245 (-)-syringaresinol as 26:243 taiwanin E as 26:243 taiwanin E methyl ether as 26:243 (+)-yangambin as 26:242 PAF-induced thrombocytopenia 26:242, 243 Paicalein 30:70 Pain 30:191,194,203 control of 30:194 sensory component of 30:191 use of ginseng root in 30:203 with cannabinoids 30:194 Pain disorders treatment 192 by COX-2 inhibitor 30:192 Pain mechanisms 30:191 Pain mediator 30:192 cytokines as 30:192 glutamate as 30:192 histamine as 30:192 leukotrienes as 192 noradrenaline as 30:192
prostaglandins as 30:192 substance P as 30:192 Pain sensation 30:201 Pain transmission 30:194 Palauolide 29:111 activity in PLA bioassay system 29:111 Palauolol 29:111 activity in PLA bioassay system 29:111 Palustroside III 25:106 hepatoprotective activity of 25:106 Pancreatic acinar cells 18:857 Pancreatic acini 12:394 from rat and mouse 12:394 Pancreatic lipase activity 30:79,88,89, 90,94,108 effect ofplatycodi radix on 30:79,88 effects of inulin extracts on 30:90 effects ofplatycodi radix extract on 30:90 in vitro 30:88,90,94 inhibiton of 30:79,108 Pancreatic lipase activity inhibition 30:86 by oolong tea 30:86 Pancreatic lipase inhibitor 30:83 orlistat (Ro 18-0647) as 30:83 Panic disorder 30:368,369 effect of circadian activity on 369 role of serotonin (5-HT) 30:368 Papaver somniferum 30:193 as analgesic 30:193 Papaya 29:592 effects on caricain chymopapain 29:592 effects on papaya proteinase papain 29:592 Papillary carcinoma 26:712 Papillomas 26:693 Papillomavirus 30:405,394 cause of cancer 30:394 cause of papillomas 30:394 Paraherquamide A 28:331,367 antiparasitic activity of 28:332 Paramyxovirus 30:408
1175 Parasitemia 25:329;30:596,694 induction by Plasmodium yoelii N67 cell line 30:596 Parasitemia inhibitor 30:597 in vivo 30:597 Parasiticidal activity 26:229 of lignans 26:229 Paratocarpin L 28:229 biological activity of 28:229 Parkinson's disease 22:310,343;25:531 Parthenin 29:91 activity in TPA assay system 29:91 activity in EPP assay system 29:91 Parthenolide 24:848,856;29:88 activity in TPA assay system 29:88 activity in iNOS assay system 29:88 activity in NFkB assay system 29:88 activity in TNFa, CRG assay system 29:88 activity in CRG assay system 29:88 antibiotic activity of 24:856 antinociceptive effects of 30:206 as anti-inflammatory 30:206 effect on NF-KB activation 30:206 Parvoviruses 30:394 Passive immunization 30:406 with hyperimmune globulin 30:406 Patellamides 28:624 as macrophage scavenger receptor inhibitor 28:624 Pathogenesis-related gene expression 25:394 Pathogenic bacteria 30:421 Legionella pneumophila 30:421 Pseudomonas aeruginosa 30:421 Shigella boydi 30:421 Pathogen-induced necrosis 25:660 Pathological anxiety 30:376 role of serotonin (5-HT) in 30:376
Pathophysiological inflammatory reactions 30:744 Patulin 24:458 FPTase inhibition by 24:458 Paw oederma 30:207 inhibition of 30:207 2-Pectenotoxin 19:580 cytoxic activity of 19:580 Pectinasic 24:995-998 enzymatic activity 24:995-998 Pectolinaringenin 30:725,748 antispasmodic activity of 30:748 Pedunculariside 29:84 activity in COX assay system 29:84 activity in EPP assay system 29:84 Pelargonidin (anthocyanidin) 29:585 effects on LELA 29:585 effects on MMP 29:582 Penates sp. 28:713 as ~-glucosidase inhibitor 28:713 Pendolmycin 15:456,462 tumour promoter activity of 15:462 Penicillins 4:432,433,435,442; 6:385;9:413;17:614-617 Penicillium turbatum 11:194 antibiotic A 26771B by 11:194 Penstemide 7:441 activity against P-388 lymphocytic leukemia 16:295 Penstemon campanulatus 24:837-838 cytotoxic activity of 24:837 Penstemon rosseus 24:838 anti-fungal activity of 24:839 Pentacyclic triterpenes 30:207 protein kinases inhibition by 30:207 Pentafubalol 20:273 Pentagastrin 25:613 Pentane 9:564 in lipid autoxidation 9:564 1,2,3,4,6-P enta- O- gallo yl-~ -D-gluc o se (galloyl ester) 29:589 effects on PEP 29:589
1176 N 1,N 4' N 7,N 1o,N 13penta -p-coumaro yl-
spermidine (coumaroyl amide) 29:573 effects on HIV- 1 protease 29:573 Peptide antagonists 18:863-865 Peptide elicitors 25:393,395,397 Peptide prohormones 25:387 Peptide signals 25:387,388 Peptide-antagonists 24:910-913 Peptides 24:522,527-533;27:804 as antiviral compound 24:522, 527-533 biological activity of 27:804 Peptidonimetic inhibitors 25:39 Pericentral hepatocyte necrosis 25:466 Perillaaldehyde 29:83 activity in AM assay system 29:83 activity in RAS assay system 29:83 iso-Perillic acid 29:83 activity in RAS assay system 29:83 Perillic acid 29:83 activity in NFkB assay system 29:83 activity in RAS assay system 29:83 Perillyl alcohol 28:426;29:83 activity in colon-1 assay system 29:83 activity in lung-1 assay system 29:83 activity in mam-2 assay system 29:83 activity in AP assay system 29:83 activity in APO assay system 29:83 activity in DIF assay system 29:83 activity in NFkB assay system 29:83 activity in RAS assay system 29:83 activity in UVB assay system 29:83
as bioactive monoterpenoid 28:426 Peripheral analgesic properties 26:400, 415 Peripheral nervous system 30:194 cannabinoid receptors in 30:194 Peripheral neuropathy 26:1130 as syndrome type-lA 26:1130 Peripheric antinociceptive effect 26:416 Peroxidase 21:356 5c~,8~x-Peroxycholesterol 5:406 cytotoxic activity of 5:406 Pervasive development disorder (PDDs) 30:372,384 asperger's syndrome (AS) 30:372 autistic disorder (AD) 30:372 childhood disintegrative disorder (CDD) 30:372 effect on social skills in 30:372 group of 30:372 Rett's disorder (RTT) 30:372 Pervasive development disorder-not otherwise specified (PDD-NOS) 30:384 Pestalotan polyol 5:319-321 antitumor activity of 5:391,320 Pestalotia sp. 5:307,308 antitum~ activity of 5:319 Pesticidal activity 18:196 of staurosperine 12:397 Pesticides 9:383,391 Petasin 29:87 activity in 5LOX assay system 29:87 activity in PLA assay system 29:87 activity in PAF assay system 29:87 Petrosia weinbergi 28:705,706 antiviral activity of 28:705 antiviral metabolites from 28:706 PGE2 25:463 as down-regulator of TNF-a 25:465 Phag-inhibitory activity 26:187 of Melia azedarach 26:187 Phagocytes 22:343
1177 Phagocytic activities 21:651 Phagocytic cells 22:112 Phagocytic chemiluminescence 24:142 Phagocytosis 21:96;24:140-142 Phakellins 21:270 Phakellistain 25:429,715,716 pharmacological effects of 25:429 Phakellistatin 5 28:683 as cytotoxic heptapeptide 28:683 Phalloidin 21:96 Pharmaceutical importance 23:497 of acaciaside 23:497 Pharmacodynamic effects 23:12 Pharmacodynamic properties 30:799 of opioid 30:799 Pharmacodynamics 23:19 Pharmacokinetic parameters 30:501 of lc~,25(OH)2D3 30:501 of 1c~,25(OH)2D4 30:501 Pharmacokinetic properties 30:799 of opioid 30:799 Pharmacokinetic studies 30:811,818 of di (DTOH) 30:811,818 of tripeptide (DTAOH) 30:811,818 Pharmacokinetic study 30:500 of 1c~,25(OH)2D analogue 30:500 Pharmacokinetic trials 30:592 Pharmacokinetics 21:258;23:19 Pharmacological actions 27:393,431; 30:55 of Baicalein 27:431 of natural products 30:55 Pharmacological activity 10:115-117; 21:4,278,457;23:247,797; 24:875-926 ;30:287,603,797,813 of acylphloroglucinols (hyperforins) 30:603 of aulacocarpinolid 23:797 ofaulacocarpin A 23:797 ofaulacocarpin B 23:797of biflavones 30:603 of deltorphin C 30:813 of dermorphin 30:813 of D-glucopyranosyl moiety 30:813
of flavonoids 30:287 of flavonol glycosides (quercetin) 30:603 of Kampo medicines 24:875-926 of Labiatae family 30:287 of metabolites 30:603 of naphtodianthrones (hypericins) 30:603 of quinocarins 10:115-117 ofningalin A 23:247 ofningalin B 23:247 of la receptor agonists 30:797 of la receptor antagonists 30:797 of 8 receptor agonists 30:797 of 8 receptor antagonists 30:797 ofrc receptor agonists 30:797 of K receptor antagonists 30:797 Pharmacological approaches 30:55 Pharmacological bioassay 30:801 of la opioid receptor 30:801 of 8 opioid receptor 30:801 Pharmacological effects 25:429 ofphakellistain 25:429 Pharmacological profiles 30:762 of Chlorella 30:762 of green algae 30:762 Pharmacological properties 22:735; 26:556-559;27:767,844 ;30:843 of earthworm fibronolytic enzymes (EFEs) 30:843 oftropane alkaloids 22:735 of resveratrol oligomers 26:556-559 Pharmacological responses 21:100 Pharmacological studies 30:304 of quinones 30:303 Pharmacological study 21:748 ofBgt A 21:754 Pharmacologically active compounds 24:848-858 Pharmacologically active polymers 30:395 Pharmacophore 4:434;21:257; 30:196,198 in carbapenem 4:434 of 3-alkyl-5-arylimidazolidinediones 30:198
1178
Pharmacophore models 12:264 Phase I trial 28:540 with monophosphoryl lipid A 28:540 Phaseoluteone 28:229 biological activity of 28:229 ct-Phellandrene 29:83 activity in AM assay system 29:83 Phenanthrene 25:542 based PKA inhibitor 25:542 Phenethylisoquinoline derivative 6:487 Phenobarbitol induced hepatic tumors 25:46 Phenolic antioxidant activity 23:766, 767 methods for evaluation of 23:766 substrates used in 23:767 Phenolic compounds 25:668 bioactivity of 25:668 Phenolic lipids 30:111,139,150-176 bioactive 30:111 biological properties of 30:150176 Phenolic triterpenes 30:674,679,691 against HT-29 (human colon carcinoma) 30:691 against MEL-28 (human melanoma) 30:691 against P-388 (mouse lymphoma) 30:691 against A-549 (human lung carcinoma) 30:691 Phenolics 24:503-509 as antiviral compound 24:503509 Phenols 30:724 pharmaceutical interes of 30:724 Phenyalkylamines 25:534 verapamil as 25:534 Phenyl propanoids 24:503-509 as antiviral compound 24:503509 Phenylacetaldehyde 28:406 acaricidal properties of 28:406 Phenylacetonitrile 28:406 acaricidal properties of 28:406 Phenylephrine-induced vasoconstriction 30:72,73,75
effect of nitric oxide (NO) synthetase 30:73 effect of xanthoangelol 30:74 effect of xanthoangelol E 30:74 Phenylethanoids 26:330 antimicrobial activity of 26:330 Phenylketonuria 30:374 autistic features in 30:374 Phenylpropanoid derivatives 28:403 acaricidal activity of 28:403 Phenylpropanoids 5:419,420,426,427; 15:29 biological activity of 5:505 Phenytoin 22:507 Pheochromocytoma 26:927 Pheromonal function 6:458 Pheromonal specificity 7:6 Pheromone activity 7:6 Pheromones 1:276,389,682-684, 695 ;7:193 ;16:138;19:122;28:428 against Tetranychus mites 28:428 fire ant 1:682,683 from Pharoah ants 1:389 from pharaoh ants 4:606 macrocyclic 8:219 of california red scale 16:138 of cigaratte beetle 1:695 of Vespa orientalis 1:684 oriental hornet 1:684 Phillygenin 26:241 as PAF-induced inhibitor 26:241 Phloretin (2',4,4',6'-tetrahydroxydihydrochalcone) 29:577 effects on aminopeptidase N 29:577 Phloretin (dihydrochalcone) 29:582 effects on MMP 29:582 Phloroglucinol derivatives 30:629 antimicrobial activity of 30:629 Phloroglucinols 30:610,629 antimicrobial activity 30:629 Phomactins 24:1062 biological activities of 24:1062 Phomasetin 28:.122 as HIV inhibitor 28:122 Phorbol ester-induced activation 12:389 inhibition of 12:389
1179 Phorbol esters 30:593 in tumor-promotion 30:593 Phorboxazole A 19:600 antifungal activity of 19:600 Phosphatidyl inositol-3,4,5-triphosphate (PIP3) 25:522,547 Phosphatidylinositol cycle 25:483,494 Phosphatidylinositol phosphateactivated proteins 25:517 Phosphatidylinositol-3,4-biphosphate (PI34P2) 25:516 2',5' -Phosphodiester 14:283 antiviral activity of 14:283 Phosphodiesterase (PDE) inhibitor 25:275,488 Phospholipase A 2 inhibitor 25:47,593 Phospholipids 24:521,522 as antiviral compound 24:521, 522 Phosphorylase kinase 27:852 activitiy of 27:852 Photodynamic activity 23:361 of coumarin 23:335,356,357, 353,368,376,393,550,553 Photosensitizing activity 23:353 of coumarin 23:335,356,357, 353,368,376,393,550,553 Phototoxic 17:378 Phyllanthus amarus 27:840 activitiy of 27:840 Phyllanthus genus 30:207,208 analgesic effect of 30:208 in treatment of hepatitis 30:207 use in folk medicine 30:207 use in kidney disturbances 30:207 use in urinary lithiasis 30:207 Physarum polycephalum 29:23 DNA polymerase activity of 29:244 Physiological activities 21:373 Physiological effects 26:207;30:192 of COX- 1 enzyme 30:192 of phytoestrogens 26:207 Physiological function 30:637,799 ofopioid system 30:799 of triterpenes 30:637 Physiological responses 21:98,109
Physostigmine 25:536;26:838 as immunosuppressive drug 25:536 Physovenine 25:536 as immunosuppressive drug 25:536 Phytoalexin 4:391,392;7:119,184; 9:221;13:637 antimicrobial properties of 16:564 Phytochemicals 21:457 as hypoglycemic agent 21:459, 488 Phytoecdysteroids 29:10 biological data of 29:11 mode of action of 29:14 Phytoestrogens 26:207 physiological effects of 26:207 Phytohormones 8:115-135,227 Phytolacca dodecandra 28:400 tick toxicity of 28:400 Phytoparasitic nematodes 22:401 Phytopathogens 21:232 Phytopolysaccharide (PS) 30:401 inhibitors of 30:401 Phytosphingolipids 18:459,460 biological activities of 18:459, 460 Phytosterolemia (lipid storage disease) 9:478 Phytotherapeutic preparations 30:703 from plants 30:703 Phytotoxic 22:626 Phytotoxic activity 15:345;21:238240;26:452 Phytotoxicity 15:479 Phytotoxins 6:554-556;15:342;17:475; 21:204;30:751 toxic effects of 30:751 PI turnover inhibitors 15:452 biological activity of 15:461,462 PI-4, PIG, CDI homologue 29:591 effects on cathepsin D, trypsin 29:591 Piclavine A 16:453 antibacterial activiy of 16:453 antifungal activity of 16:453 Picornavirus 30:406 Picrotoxin 22:508
1180 Piericidin A 28:436 as complex I inhibitor 28:436, 437 Piericidin 28:435 as inhibitor of 28:435 Pilocarpine 22:19 Pimagnolin 30:592 as EBV inhibitor 30:592 Pimenta dioica 28:403 acaricidal activity of 28:403 Pimpinella anisum 28:427 acaricidal activity of 28:427 Pinocembrin 28:229 biological activity of 28:229 (+)-Pinoresinol dimethyl ether 26:241 as PAF-induced inhibitor 26:241 Pinusolide 29:102 activity in CRO bioassay system 29:102 Piper amides 24:683-783 biological activity 24:708-715 isolation of 24:705-708 Piperbetol 26:243 as PAF-induced inhibitor 26:243 Piperidine alkaloid hydrochloride 30:204 antinociceptive action of 30:204 Piperitenone 29:83 activity in AM assay system 29:83 (+)-Piperitone 29:83 activity in AM assay system 29:83 Piperol A 26:243 as PAF-induced inhibitor 26:243 Piperol B 26:243 as PAF-induced inhibitor 26:243 Piperylene 24:708 Piqueria trinervia 24:779,817-819 herbicidal activity of 24:819 Piquerol A 28:404,405 acaricidal activity of 28:404 Piquerol B 28:404 acaricidal activity of 28:404 toxicity to gravid female ticks 28:404 Pironetin 30:3,26-46 against transplanted murine tumor
cell lines P 388 leukemia 30:27 antitumor activity of 30:27,28 as antitumor agent 30:3 as immunosuppressive agent 30:3 as plant growth regulator 30:26 biological activity of 30:26 effect on 3Y1 cell 30:27 effect on cell cycle progression 30:27 effect on DNA content 30:27 immunosuppressive effect of 30:26 Pironetin derivatives 30:27 effect on uterine tumor 30:27 effect on ovarian tumor 30:27 Piscicidal activity 2:289 of frullanolide 2:289 of liverwort terpenes 2:289 ofplagiochiline A 2:289 of polygodial 2:289 of sacculatal 2:289 Pisiferic acid 29:170 antibacterial activity of 29:170 antifungal activity of 29:170 effects on DNA synthesis 29:170 PKA 25:541 inhibitor of 25:541 PKA inhibitors 25:527,538,542,550 acridine based 25:542 ellagic acid as 25:550 isoquinoline based 25:542 phenanthrene based 25:542 PKA-catalyzed phosphorylation 25:529 PKA-gated Na + channels 25:521 PKC activation 30:71 inhibition of 30:71 PKC inhibitor 25:544,550 ellagic acid as 25:550 Placenta 30:561 role of Hernandia moerenhoutiana in 30:561 role of Hernandia nymphaeifolia in 30:561 role of Hernandia voyronii in 30:561
1181
Plant extracts 24:524-526 in vitro antiviral activity 24:524-526 Plant growth regulator 26:934-935 role of nitric oxide in 26:934-935 Plant growth regulatory activity 2:289 of liverwort terpenes 2:289 of polygodial 2:289 Plant growth stimulants 9:383,384 Plant Kunitz serine protease inhibitor proteins 29:603 ACTI-A (ACTI-A-S-S- ACTI-B) as 29:603 A-II & A-Ill (22 kDa), B-I & BII as 29:603 BASI (barley a-amylase & subtilisin inhibitor) as 29:604 BnD22 as 29:603 BoKPI as 29:603 Carica KPI as 29:604 CLSI-II as 29:603,604 CoATi as 29:606 DE5 as 29:603 DrTI as 29:604 ECI as 29:604 effects on actinidin ananain 29:606 effects on chymotrypsin 29:603,604 effects on chymotrypsin kallikrein plasmin 29:604 effects on chymotrypsin 29:604 effects on elastase 29:603,606 effects on ETI-a - plasminogen activator 29:604 effects on Factor XIIa 29:603 effects on inferred KPI (wounding-induced Kunitz homologue) 29:605 effects on Kallikrein 29:603,604 effects on KPI homologues 29:604 effects on Kunitz PI homologue 29:605 effects on serine protease 29:603 effects on soybean KPI
homologue 29:605 effects on STI (Kunitz) homologue 29:604 effects on subtilisin 29:604,605 effects on subtilisin BPN' proteinase K 29:603 effects on trypsin 29:603,604 Enterolobium EcTI as 29:604 Erythrina DE-I, DE-2, DE-3, DE-4 as 29:604 Erythrina ETI-a ETI-b as 29:604 from Acacia confusa 29:603 from Adenanthera pavonina 29:603 from Albizziajulibrissin 29:603 from Alocasia macrorrhiza 29:603 from Arabidopsis thaliana 29:603 from Bauhinia bauhinioides 29:603 from Bauhinia mollis 29:603 from Bauhinia pentandra 29:603 from Bauhinia variegata (mountain ebony) 29:603 from Brassica napus 29:603 from Brassica oleraceae 29:603 from Canavalia lineata 29:603,604 from Carica papaya 29:604 from Delonix regia 29:604 from Enterolobium contorsiliquum 29:604 from Erythrina caffra 29:604 from Erythrina latissima 29:604 from Erythrina variegata 29:604 from Glycine max 29:604 from Hordeum vulgare 29:604 from Ipomoea batatas 29:604 from Lycopersicon esculentum 29:604 from Nicotiana glauca 29:604 from Nicotiana glutinosa 29:605 from Nicotiana langsdolffii 29:604 from Oryza sativa (rice) 29:605 from Pisum sativum (pea) 29:605 from Populus deltoides 29:605
1182 from Populus balsamifera 29:605 from Populus tremuloides 29:605 from Populus trichocarpa 29:605 from Prosopisjuliflora 29:605 from Psophocarpus tetragonolobus 29:605 from Richadella dulcifica 29:605 from Salix viminalis 29:605 from Schizolobium parahybum 29:605 from Solanum tuberosum 29:605 from Swartzia pickellii 29:606 from Theobroma cacao 29:606 from Triticum aestivum 29:606 Gt-fucosidase as 29:605 pF4 & pKEN 14-28 KPI genes as 29:606 T-CDI-B1 KPI genes as 29:606 genes encoding KPI-like proteins as 29:603 GTPI as 29:603 gwin3 as 29:605 heat-stress-induced protein (HTI) as 29:603 KPI as 29:603 KTi-S as 29:604 Kunitz PI homologue AM66 as 29:606 Lycopersicon Miraculin-like protein as 29:604 Lycospersicon TI gene as 29:604 miraculin (MIR) as 29:605 NgPI as 29:605 p20 as 29:604 p340 & p34021 as 29:606 PCPLs homologues as 29:606 PI-4, PIG, CDI homologue as 29:605 PjKTI as 29:605 PKI-1 as 29:606 potato cysteine protease inhibitor as 29:605 potato serine protease inhibitors PSPI-21-5.2 as 29:606 Pt nodulin as 29:605 pTI as 29:606
PtTI1, PtTI2 & PtTI3 as 29:605 rice c~-amylase-subtilisin inhibitor as 29:605 SPC as 29:605 sporamin A & sporamin B as 29:604 SVTI as 29:605 SWINI.1 as 29:605 SWTI as 29:606 TPP 11 (gene expressed in flower tissue) as 29:604 tumour-related protein as 29:604 WASI as 29:606 water-soluble chlorophyllcarrying protein as 29:603 WBA-1 as 29:605 WBTI-2 as 29:605 WTI-1 as 29:605 Plant peptides 29:594 effects on ACE enzyme 29:594596 Plant polyphenol 28:257,281,300 bioactivity of 28:257 epidemiological studies on 28:300 in humans 28:281 Plant regulatory activity 28:480 ofpodolactone E 28:480 Plant serpins 29:613 effects on 4APC, cathepsin G 29:613 effects on cathepsin G 29:613 effects on chymotrypsin 29:613 effects on elastase 29:613 effects on elasta~e, factors VIIa/TF, Xa, XIIa, kallikrein 29:613 effects on serine protease 29:613 effects on thrombin 29:613 effects on trypsin 29:613 WSZ1 as 29:613 WSZlb as 29:613 Plants 24:490-544;25:459 antiviral compounds from 24:492-544 as antiviral agents 24:490-544 hepatoprotective effect of 25:106 Plaque forming units (PFU) 24:483
1183 Plasma glucose 27:412 biological activity of 27:412 Plasma LDL 23:739 Plasma membrane H+-ATPase 25:374 Plasma membrane-located receptors 25:518,522 Plasma-cholestrol lowering activity 23:512 of saikosaponins 23:512 Plasma-membrane-located signals receptors 25:518 Plasmin-activator 30:839 EFE as 30:839 Plasminogen activator (e-PA) 30:826 from Eiseniafetida 30:827 Plasminogen activator (t-PA) 25:221 Plasminogen activator inhibitor (PAl) 30:844 Plasminogen activator inhibitor- 1(PAIl) 27:433,435 Plasminogen inhibitors 30:841 from Eisenia fetida 30:841 role in tissue protection 30:841 Plasmodium strains 30:694 against human adenocarcinoma cell line HT-29 30:694 Platelet 30:593 role in hemostatic process 30:593 Platelet activating factor antagonist activity 26:183 effect of Schisandra on 26:183 Platelet activating factor (PAF) 26:240-245 ;30:594 and antagonism 26:240-245 and coagulation 26:240-245 as potent phospholipid inflammatory mediator 28:188 by inhibiting phospholipase A2 12:397 platelet aggregation induced by 30:594 Platelet activation 30:70 role of serine protease in 30:70 role of thrombin in 30:70 Platelet aggregation 12:397;21:263; 26:756,758;30:593,594,838 arterial thrombosis due to 30:593 collagen induction by platelet
activating factor (PAF) 30:594 induction by arachidonic acid 30:594 induction by thrombin 30:594 inhibition of 12:397 Platelet aggregation inhibition 23:357 of osthole 23:357 and ovarian cancer 23:294 Platelet aggregation inhibitor 1:4; 28:16,17;30:594 broussoaurone A as 28:16,17 broussoflavan A as 28:16 broussoflavonol E as 28:17 broussoflavonol F as 28:17 (-)-deoxypodophyllotoxin as 30:595 (-)-hernone as 30:595 (-)-yatein as 30:595 (+)-epiaschantin as 30:595 (+)-epimagnolin as 30:595 (+)-epiyangambin as 30:595 (+)-hernandaline as 30:594 (+)-laurotetanine as 30:594 (+)-malekulatine as 30:594 (+)-ovigerine as 30:594 (+)-reticuline as 30:595 (+)-thalicarpine as 30:595 (+)-vateamine-2 ' [3-N-oxide as 30:595 7-oxohernagine as 30:595 dehydrohernandaline as 30:594 Hernandia species as 30:594 hernangerine as 30:594 isoquinoline alkaloids as 30:594 isovanillin as 30:594 lignans as 30:594 N-methylhernangerine as 30:594 Platelet antiaggregant 25:595 Platelet arachidonate metabolism 27:422 of polyacetylene compounds 27:422 Platelet serotonin (5-HT) 30:380 in autistic patients 30:380 Platelet-derived growth factor (PDGF) 15:441 ;25:593,598 Platycodi radix 30:89,91 effects on liver triacylglycerol 30:89
1184
effects on liver weight 30:89 effects on plasma triacylglycerol level 30:90 effects on total cholesterol 30:89 Pleiotropic effect of TNF-a 25:460 Plicacetin 4:244 activity of 4:244 PMA 25:938 inhibitor of 25:938 PMA-thrombin 30:70 inhibition of 30:70 PM-located voltage-gated Ca 2+channels 25:534 PMT 21:157,176,177 preclinical development of 21:176 Podachaenin 29:90 activity in NFkB assay system 29:90 Podolactones 28:453,454,455,495 antifeedant activity of 28:454 anti-inflammatory activity of 28:453,454 anti-tumor activity of 28:453,454 biogenetic pathway for 28:455 fungicidal activity of 28:453,454 growth regulatory activity of 28:454,453 insecticidal activity of 28:453, 454 Podophyllum 26:210 antitumor activity of 26:210 Podophyllum extracts 26:169 of antiviral activity 26:169 Podorhizol 30:569,592 as EBV inhibitor 30:592 Polio virus 30:411,743 replication of 30:411,743 use of antivirals 30:411 Polio virus type 1 30:743 antiviral activity of 30:743 Polio virus type 3 30:326 aloe-emodin against 30:326 Poliomyelitis 30:394,411 transmission of 30:411 vaccination against 30:411 Poliovirus SV 24:524 activity of actinoplanic acids against 24:524
Polyacetylenes 24:521,522,541-544 as antiviral compound 24:521, 522,541-544 Polycarpamine A 28:640 as sulfur-containing antifungal agent 28:640 Polycarpamine B 28:640 as sulfur-containing antifungal agent 28:640 Polycarpamine C 28:640 as sulfur-containing antifungal agent 28:640 Polycarpamine D 28:640 as sulfur-containing antifungal agent 28:640 Polycarpamine E 28:640 as sulfur-containing antifungal agent 28:640 Polycavernoside A 19:572 toxicity of 19:572 Polyclonal antibodies against ARS2 25:435 Polyenal macrolides 6:261 biological activity of 6:261 in candidoses 6:261 in tumor therapy 6:261 Polyene antibiotics 25:299 Polygnum cuspidatum 27:405 for hyperlipidaemia 27:405 Polygodial 1:467,468;2:278,279,286, 289;6:108;7:103,110,121-123; 17:235,244 ;29:87 ;30:193,206 activity in EBV assay system 29:87 activity in Skin 1 assay system 29:87 activity in CRG assay system 29:87 activity in CRO assay system 29:87 activity in AA assay system 29:87 activity in BRK assay system 29:87 activity in CPS assay system 29:87 activity in HTM assay system 29:87 activity in PAF assay system
1185
29:87 antinociceptive action of 30:206 piscicidal activity of 2:289 Polygonum sp. 27:405 biological activity of 27:405 Polyhydroxyindolizidines 27:252 biological activity of 27:252 Polyhydroxylated 2-phenylnaphthalenes 30:225 effect on 5-1ipoxygenase inhibition 30:225 Polyketides 24:1050 cytotoxic effects of 24:1055, 1085 Polymastiamide A 28:704 as antimicrobial steroid 28:704 Polymerase activity 25:826 Polymerase chain reaction (PCR) 30:384,843 Polymixin B 12:387 protein kinase inhibitor of 12:387 Polymorphonuclear leukocytes 25:432 Polyoxins 1:404 antifungal action of 1:399 chitin synthetase inhibition by 1:399 Polyphenol assay 21:524 Polyphenol oxidase inhibitors 21:587 Polyphenols 7:409;17:421,427429;28:177,257,293 ;30:224,226,227 anti-atherosclerotic activity of 28:257,293 anti-carcinogenic activity of 28:257,293 anti-inflammatory activity of 28:200,257,293 anti-microbial activity of 28:257,293 anti-oxidant activity of 28:257,293 anti-HIV activity of 30:226 antiinflammatory activity of 30:224 antimitotic activity of 30:224 anti-tumor activity of 30:224 antiviral activity of 30:224 anxiolytic activity of 28:177
as anti-HIV agents 30:227 biological activities of 30:224 Polyporic acid 29:265 antibacterial activity of 29:265 as antileukemic principle 29:265 effects on dihydroorotate dehydrogenase enzyme 29:266 effects on lipid peroxidation 29:266 Polyprenols (dolichols) 8:64 as antiinflammatory agents 8:64 Polysaccharides 5:275-340;7:31-33, 72 ;8:315 ;9:296,297 ;24:540,541,1003 - 1004,1009,1077 antigenicity of 19:689-745 as antitumor agent 5:315 as antiviral compound 24:540, 541 as cell-surface antigens 5:322 enzymatic activity 24:10031004,1009,1077 Polysaccharidic molecule 30:395 as virus inhibitor 395 Post translational modification 25:367 Potassium salt of caffeic acid tetramer 24:742,743 anti-HIV activity of 24: 742 Potato carboxypeptidase inhibitor 29:596 GM7 as 29:596 Potato disc bioassay 9:399,401,402 Potato discs 9:399 crown gall tumors on 9:399 Potato multicystatin PMC proprotein: 29:593 effects on papain PMC 29:593 Potato type I serine protease inhibitors 29:607 Af4 gene product as 29:608 amaranth trypsin inhibitor (AmTI) as 29:607 Arabidopsis genes encoding- 8 potato type 1 serine protease inhibitors as 29:607 ASI-I as 29:609 BGIA as 29:608 Bm7 & Prl0 as 29:608 BTI-1 & BTI-2 as 29:608 BWI-1 as 29:608
1186 BWI-3c; BWI-4c as 29:608 BWI-4a as 29:608 CI-la & CI-lb as 29:608 CI-lc 29:608 CI-2 29:608 CMTI-V as 29:608 DI-1 as 29:608 effects on activated Hageman factor (XIIa), trypsin 29:608 effects on bacterial subtilisin-like proteases 29:608 effects on cathepsin G 29:607 effects on chymotrypsin 29:607609 effects on factor XIIa 29:607 effects on Glu-specific protease 29:608 effects on plasmin 29:607 effects on serine protease 29:609 effects on Streptomyces griseus glutamate endopeptidase 29:608 effects on subtilisin 29:607,609 effects on subtilisin BPN' 29:607 effects on subtilisin carlsberg 29:607 effects on Streptomyces alkaline 29:607 effects on protease 29:607 effects on ,4spergillus protease 29:607 effects on proteinase K 29:607 effects on Bacillus protease 29:607 effects on pronase 29:607 effects on trypsin 29:608 effects on chymotrypsin 29:608 effects on cathepsin G 29:608 ERI as 29:608 from Amaranthus caudatus 29:607 from Amaranthus hypochondrionacus 29:607 from Arabidopsis thaliana 29:607 from Canavalia lineata 29:607 from Cucurbita maxima 29:608 from Fagopyrum esculentum 29:608
from Hordeum vulgare 29:608 from Linum usitatissimum 29:608 from Lycopersicon esculentum 29:608 from Momordica charantia 29:608 from Nicotiana glauca x N. langsdorffii 29:609 from Nicotiana sylvestris 29:609 from Nicotiana tabacum 29:609 from Sambucus nigra 29:609 from Viciafaba 29:609 from Vigna (Phaseolus) angularis 29:609 from Zea mays (corn) 29:609 GTI as 29:609 LUTI as 29:608 maize protease inhibitor as 29:609 MCI-3 as 29:608 NSTI-I as 29:609 PI-I variant as 29:609 PI-I variants A, B, C & D as 29:609 PIN1 as 29:609 pumpkin fruit trypsin inhibitor as 29:608 Sambucus SPI as 29:609 subtilisin inhibitor as 29:607 TI-1 as 29:608 Vicia PI-I as 29:609 Potato type II serine protease inhibitors 29: 610 ARPI as 29:610 aubergine as 29:611 CEVI57 as 29:610 6-domain PI precursor NaProPI (NaPI II) as 29:610 4-domain PI-II precursor NaPI IV as 29:610 effects on chymotrypsin 29:610 effects on pronase 29:610 effects on Streptomyces griseus proteinase B 29:611 effects on trypsin 29:610 from Capsicum annuum 29:610 from Lycopersicon esculentum 29:610
1187 from Nicotiana alata (ornamental tobacco) 29:610 from Nicotiana alata 29:610 from Nicotiana glutinosa 29:610 from Nicotiana tabacum 29:611 from Solanum americanum 29:611 from Solanum melongena 29:611 from Solanum tuberosum 29:611 PCI-I as 29:611 Pepper leaf PIs as 29:610 PI-II as 29:611 PI-II K as 29:611 PI-II precursor PI2-1 as 29:611 PI-II precursors NGPI-1 as 29:610 P I-II variants B, C & D as 29:611 Pin2-L as 29:611 Pin2-R as 29:611 PSI-1.1 as 29:610 PTI as 29:611 SaPIN2a & SaPIN2b as 29:611 Potato viruses 30:412 antiviral activity against 30:412 PP inhibitors 25:521 PP1 inhibitors 25:543 PP2A inhibitors 25:543 pp60v-src protein tyrosine kinase inhibition activity 28:698 of halistanol sulfate 28:698 PPO activity 25:656 Pramanicin 28:149,150 as antifungal agent 28:149 Preclinical development 21:176 of HMR1826 21:176,177 Preclinical development 21:176,177 of A.D.E.P.T. 21:176,177 of benzylcarbamate prodrug HMRI826 21:176,177 of P.M.T. 21:176,177 Predator mites 28:434 as pathogen 28:434 Pregomisin 26:244 as PAF-induced inhibitor 26:244 Prehispanolone 25:273 effect on B cell proliferation 25:273
6-Prenyleriodictyol 28:229 biological activity of 28:229 8-Prenyleriodictyol 28:229 biological activity of 28:229 Prenylflavones 28:225 anti-human immunodeficiency virus (HIV) activity of 28:226 Prenylfiavonoid 30:207 antinocicieptive effect of 30:207 Prenyl-naphthoquinone lapachol 29:719 antibacterial activity of 29:720 anticancer activity of 29:720 antifungal activity of 29:720 antitrypanasomal activity of 29:747 antitumor promoting activities of 29:720 as cytomegalovirus protease inhibitors 29:720 as photosensitizer 29:739 biological activities of 29:719 use in cancer 29:720 use m colds 29:720 use m debilitating 29:720 use in diabetes 29:720 use m dysentery 29:720 use in fevers 29:720 use in flu 29:720 use in gastro-intestinal problems 29:720 use in Hodgkins disease 29:720 use in infections 29:720 use in lupus 29:720 use in osteomyelitis 29:720 use in Parkinson's disease 29:720 use in psoriasis 29:720 use in respiratory problems 29:720 use in skin ulcerations 29:720 use in syphilis 29:720 6-Prenylnaringenin 28:229 biological activity of 28:229 Pretazettine 15:135 physiological properties of 4:13 Prevention by carp extract 27:439 of gastrointestinal toxicity 27:439 of myelotoxicity 27:439
1188
Prevention by chitosan 27:436 of myelotoxicity 27:436 Primary biliary cirrhosis 25:463 Primary granulosa cells 25:269 apoptosis in 25:269 Primary solid-tumor growth 30:64 effect of triterpenoids on 30:64 Pristimarin 30:692 cytotoxic activity of 30:692 PRL1 & PRL2 proproteins 29:592 effects on cysteine protease 29:592 Pro-apoptopic 27:851 Probes 27:332 activity of 27:346 Procurcumenol 29:90 activity in TNFct assay system 29:90 Procyanidin (condensed tannin) 29:585 effects on LELA 29:585 Procyanidin B 1 (dimeric flavan-3-ol) 29:580 effects on ACE 29:580 Procyanidin B2 (dimeric flavan-3-ol) 29:580 effects on ACE 29:580 Procyanidin B-2 3,3'-di-O-gallate (condensed tannin) 29:580 effects on ACE 29:580 Procyanidin B-5 3,3'-di-O-gallate 29:580 effects on ACE 29:580 Procyanidin C2 (trimeric flavan-3-ol) 29:580 effects on ACE 29:580 Procyanidin polymer (flavan-3-ol polymer) 29:580 effects on ACE 29:580 Procyanidins (polyphenolic oligomers) 29:582 effects on collagenase 29:582 Prodrug monotherapy 21:157 natural anthracyclines for 21:157 Prodrugs 21:157 of natural anthracyclines 21:157 Pro-inflammatory cytokines 25:461
Pro-inflammatory substances 30:206 in chronic painful inflammatory diseases 30:206 Proliferation 30:368,378 effect of serotonergic neurotransmission on 30:368 serotonin action on 30:378 Prolysine 25:388 prophylactic effects of 25:429 Pro-nociceptive prostaglandins 30:192 in inflammation 30:192 Pro-nociceptive transmitter 30:194 release inhibition of 30:194 Prooxidant activities 30:745 in thiobarbituric acid assays 30:745 of chemiluminescence 30:745 of tert-butyl hydroperoxide 30:745 Prooxidant property 30:524 of carotenoids 30:524 Prophylactic drugs 30:407 Prophylactic effect 25:429 ofprolysine 25:388 Prostaglandin E2-dependent flavonoids cytoprotection effect of 25:607 Prostaglandin endoperoxide receptor antagonist 25:593 Prostaglandin H2 (PGH2) 25:595 Prostaglandin inhibitors 30:192 clinical use of 30:192 use in rheumatism 30:192 use in osteoarthritis 30:192 use in headache 30:192 use in dental surgery 30:192 Prostaglandin synthetase inhibitors 5:815-833 Prostaglandin synthetase inhibitory activity 21:591 Prostaglandins 1:686,687;5:377,815833 ;7:483 ;9:290,559,571 ;13:659; 17:642;19:550;24:541-544 ;30:192 anticancer clavulones 16:366 as antiviral compound 24:541544 as pain mediator 30:192 in mast cells 30:192 nociceptive effect of 30:192 Prostate cancer 23:294
1189
Prostate cancer prevention 30:525 role of lycopene in 30:525 Prosystemin cDNA 25:370 Protease inhibitor proteins from plants 29:596 effects on metallo-carboxy peptidase 29:596 Protease inhibitors 24:487,488; 26:800;29:567 Bowman-Birk as 29:567 cereal bifunctionals as 29:567 chymotrypsin as 29:568 destructive potential of 29:568 in Alzheimer's disease 29:567 in angiogenesis 29:567 in cancer inflammatory disease 29:567 in protozoal infection 29:567 in viral infection 29:567 Kunitz as 29:567 mustard family of 29:567 of metallocarboxypeptidase 29:567 ofserine protease 29:567 pepsin as 29:568 phytocystatins as 29:567 potato type 29:567 proteins as 29:567 serpin as 29:567 trypsin as 29:568 Proteases 24:1005;29:567 enzymatic activity 24:1005 in apoptosis 29:567 in blood clotting 29:567 in cell division 29:567 in digestion 29:567 in extracellular matrix digestion 29:567 in inflammatory responses 29:567 in peptide bond hydrolysis 29:567 in protein destruction 29:567 regulation of 29:568 Protein kinase inhibitor 23:168,180 secosterols as 23:168,180 Protein kinase A (PKA) 192 in regulation of ionotropic receptors 30:192
Protein kinase activity 28:677 ofxestoquinolide B 28:677 Protein kinase C (PKC) activator 30:70 Protein kinase C inhibition 24:573; 25:46,488 by xestocylamine 24:573 Protein kinase inhibition 30:207 by pentacyclic triterpenes 30:207 Protein kinases 27:826 activitiy of 27:826 Protein phosphatase inhibitors 27:874 Protein phosphatases 25:707 inhibitor of 25:707 Protein synthesis 30:407 inhibitor of 30:407 Protein transduction domain (PTD) 30:840,844 Proteinaceous receptor 25:371 Proteinase activity 21:150 Protein-coupled receptor 27:821 GProteine kinase C activity 21:638 Proteins 24:522,527-533 as antiviral compound 24:522, 527-533 Protein-tyrosine kinase activity 27:842 offlavonoid aglycones 27:842 of glycosides 27:842 ofKoelreuteria henryi 27:842 Protein-tyrosine kinase inhibitory activities 27:839 Protein-tyrosine kinases (PTK) 9:390, 391 inhibition by piceatannol 9:390, 391 Proteolytic activity 30:841 Proteolytic systemin inactivation 25:375 Protium kleinii 30:206 anti-inflammatory effect of 30:206 antinociceptive effect of 30:207 Protocatechuic acid (3,4-dihydroxybenzoic acid) 29:589 effects on PEP 29:589 Proton pump inhibitors (PPIs) 25:612 Proton-translocating NADH:Q oxidoreductase 28:435 high-affinity inhibitors of 28:435
1190
Protozoocidal activity 30:329,741,742 against Leishmania 30:329 against Plasmodium 30:329 against Tryponosoma 30:329 genus Baccharis 30:741 in vitro 30:329 of neo-clerodane diterpenoids 30:742 ofquinone derivative 30:329 Protozoocidal compounds 30:740 use of 30:740 Proxyelocytic leukaemia (HL-60) cells 27:842 Prunella vulgaris 30:401 antiviral activity of 30:401 Psammaplin A (bisprasin) 28:693 effects on Bacillus subtilis 28:693 Psammaplysilla purpurea 28:693 antimicrobial activity of 28:693 as tyrosine kinase inhibitor 28:693 Pseudobersana mossambicensis 20:478 bioactive steroids from 20:476 Pseudoguaiane 11 a,13-dihydrohelenalin acetate 29:90 activity in CRO assay system 29:90 Pseudohypericin 7:421 ;30:608,627 against cytomegalo virus 30:627 against human immunodeficiency virus-1 30:627 against influenza virus 30:627 as virucidal agents 30:627 retroviral activity of 7:421 Pseudolaric acid B 13:653;21:754-759 antifertility activity of 21:758 antifungal activity of 21:758 as fertility-regulating agent 13:653 Pseudomonas aeruginosa 30:739 antibacterial activity against 30:739 antifungal activity against 30:739 Pseudo-oligosaccharide inhibitors 10:503
Pseudorabies virus 30:404 in vitro replication of 30:404 role ofheparin 30:404 PSII inhibitors 26:368,371 PSK in mitosis 25:377 PSK-receptor 25:378 PSK-a activity 25:378 Psoriasis 30:484 use of lc~,25(OH)2D3 30:484 Psychiatric disorders 30:369 anorexia 30:369 bipolar disorder 30:369 bulimia 30:369 effect of circadian activity on 30:369 obsessive compulsive disorder 30:369 panic disorder 30:369 schizophrenia 30:369 seasonal effective disorder 30:369 unipolar depression 30:369 Psychodelic drugs 26:820 cocaine as 26:820 morphine as 26:820 semisynthetic LSD as 26:820 Psychological effects 21:580 Psychomotor retardation 26:1130 as syndrome type-lA 26:1130 Psychoses 21:101 Psychotropic activity 7:7 Psychovegetative disorders 22:643,684 Psycotria colorata 30:205 to relieve abdominal pain 30:205 Puberulin A 26:243,244 as PAF-induced inhibitor 26:244 Puberulin C 26:243,244 as PAF-induced inhibitor 26:244 (+)-Pulegone 29:83 activity in AM assay system 29:83 Pulmericin 16:299 antifungal activity of 16:299 antileukemic activity of 16:299 cytotoxic activity 16:299 Pulmonary colonization 19:370 Pulmonary tumors 24:224,232,261
1191 Pulmonary vascular injury 30:70 role of serine protease in 30:70 role of thrombin in 30:70 Pumiliotoxin alkaloids 27:238,239 alIo-PTX 323 B alkaloid 27:249,250 biological activity of 27:249,250 Pumiliotoxin B 12:294 activity of 12:294 Punta Toro virus 30:411 treatment of 30:411 Purifying blood 26:50 Herniaria hirsuta in 26:50 Purine receptors 25:532 Purpurogallin (2,3,4,6-tetrahydroxy5H- effects on PEP 29:589 Putative receptor proteins 25:398 Putative satiety factor 24:910 effect of cholecystokinin 24:910 Pyranocoumarin 27:429 biological activity of 27:429 Pyranoid carbasugars 29:466 as cellular messengers 29:467 as insulin release mediators 29:467 biological activities of 29:466 effects on glycosidase enzyme 29:467 effects on glycosyltransferase enzyme 29:467 galactosyltrans ferase inhibition by 29:472 (-)-Pyrenophorin 19:154-155 antifungal antiobiotic 19:154155 Pyrethrin analogues 14:397-405 insecticidal activity of 14:398 Pyridoacridine alkaloids 28:639 cytotoxic effects on KB cells 28:639 Pyrimidine phosphorylase 4:230 inhibition of 4:230 Pyrones 24:541-544 as antiviral compound 24:541544 Pyrrole-imidazole alkaloid 28:690 taurodispacamide A 28:690 antihistaminic activity of 28:690
Pyrrolidines 10:524 glycosidase inhibitors of 10:524 Pyrrolomycin antibiotics 25:794 Pytressin-induced coronary spasm 25:594 Quassinoids 7:391-394 antileukaemic activity of 7:382387 antimalarial activity of 7:391394 antitumor activity of 11:71-111 toxicity of 7:388,389 3,5,6,7,3 ',4'-Quercetagetin (6-hydroxy quercetin hexahydroxyflavone) (flavonol) 29:573 effects on HIV- 1 protease 29:573 Querc etin (3,5,7,3 ',4'-pentahydroxyflavone) 29:578;30:208,749 analgesic effect of 30:208 effects on aminopeptidase N 29:578 effects on ACE 29:580 effects on HIV- 1 protease 29:573 effects on LELA 29:585 effects on NEP 29:581 effects on PEP 29:589 Quercetin 3-O-c~-L-arabinopyranoside 28:64 anti-oxidant activity of 28:64 Quercetin 3-O-c~-L-rhamnopyranoside 28:64,65 anti-oxidant activity of 28:64,65 Quercetin 3-O-[3-D-galactopyranoside 28:64 anti-oxidant activity of 28:64 Quercetin-3-O-(2"-O-galloyl)glucoside 29:580 effects on ACE 29:580 Quercetin-3-O-ot-L-rhamnopyranoside 28:64 anti-oxidant activity of 28:64 Quercitrin (quercetin-3-rhamnoside) 29:581 effects on ACE 29:581
1192
Quillaia 26:55 of adjuvant activity 26:55 Quinidine 25:347 Quinine 25:344,347,478,546 Quinocarcin 10:117;19:290 antitumor activity of 10:117 inhibitor of DNA 19:290 (-)-Quinocarcin 19:289 antimicrobial activity of 19:289 antitumor activity of 19:289 Quinoline antimalarial drugs 25:329, 348,349 Quinoline drugs 25:348 Quinoline drug family 25:343,360 Quinoline-based antimalarials 25:344 Quinoline-ring antimalarial drugs 25:327 Quinolines 25:327,345,347,348 Quinolizidine alkaloid 27:233,276,287 bioactivity of 27:233 Quinolizidine derivatives 27:284,285 testing against Mycobacterium tuberculosis 27:284 Quinone 24:503-509,541-544 as antiviral compound 24:503509,541-544 Quinone methides 30:694 antiplasmodial activity of 30:694 Quinones 7:427 molluscicidal activity of 7:427
Rabidaea platyphylla 22:513 for epilepsy 22:513 Rabies virus 30:409 inhibitor of 30:409 Rabies virus infection 30:409 in chicken-embryo-related cells 30:409 Rabies virus replication 30:409 in nerve fibers 30:409 Rachitic bone healing potencies 484 of vitamin D2 30:484 of vitamin D3 30:484 of vitamin D4 30:484 of vitamin D5 30:484 of vitamin D6 30:484 of vitamin D7 30:484
Radical scavenging activity 23:362 of coumarin 23:335,356,357, 353,368,376,393,550,553 Radioligands 30:814 from brain membrane synaptosomes 30:814 Radioprotecitve effect 23:134 Radioprotective activity 23:107 of [3-glucans 23:107 Random screening 24:415-4 ! 8 of chemical selection 24:415,416 of combinatorial libraries 24:417 of compound libraries 24:415418 Ranitidine 25:612,617 rANP-triggered signal transduction 25:382 Rapamycin 25:892 Raphe nuclei 30:368 role in cognitive functions 30:368 Ras farnesyltransferase inhibitors 21:404 Ras function inhibitors 15:450,451 compactin 15:450,451 oxanosine 15:449 Ras oncogenes 22:621 Rat brain synaptosomes 30:807 p-affinity in 30:807 Rat mammary carcinogenesis model 30:592 cancer chemopreventive activity in 30:591 Rat serum vitamin D-binding protein (DBP) 30:494 binding assay for 30:494 Rauscher leukemia virus 21:430 Rebaudioside A 29:101 activity in TPA bioassay system 29:101 Rebaudioside C 29:101 activity in TPA bioassay system 29:101 Rebeccamycin 5:55,56 antitumor activity 1:394 Rec-assay 28:225 of 6-prenyleriodictyol 28:225 of 8-prenyleriodictyol 28:225 ofgancaonin C 28:225
1193
of isoliquiritigenin 28:225 of licoisoflavanone 28:225 oflicoisoflavone B 28:225 ofsemilicoisoflavone B 28:225 [31-[33Receptor 21:18 o~-Receptor 21:58 [5-Receptor 21:58 8-Receptor 22:296 ~-Receptor 22:296 8-Receptor affinity 30:814 binding properties of 30:814 ~t-Receptor affinity 30:814 binding properties of 30:814 of glycopeptide 30:814 8-Receptor agonists 30:797 pharmacological activity of 30:797 K-Receptor agonists 30:797,806 pharmacological activity of 30:797 ~.t-Receptor agonists 30:797 pharmacological activity of 30:797 8-Receptor antagonists 30:797 pharmacological activity of 30:797 K-Receptor antagonists 30:797 pharmacological activity of 30:797 ~t-Receptor antagonists 30:797 pharmacological activity of 30:797 Receptor binding 27:377 Receptor binding assay 30:810 in vitro 30:810 mouse vas deferens (MVD) activity in 30:810 of guinea-pig ileum (GPI) 30:810 Receptor binding properties 30:815 of Tyr-D-Ala-Phe- [[3-DGlc(OAc)4]Tyr-Pro-Ser-NH2 30:815 of Tyr-D-Ala-Phe-Asp-Val-ValGly-NH2 (deltorphin C) 30:815 of Tyr-D-Ala-Phe-Asp-Val-ValThr(13-d-Glc)-Gly-NH2Tyr-DAla-Phe-Thr[[3-D-Glc(OAc)4]-
Val-Val-Gly-NH2 30:815 of Tyr-D-Ala-Phe-Asp-Val-ValThr[[3-d-Glc(OAc)4]-Gly-NH2: 30:815 of Tyr-D-Ala-Phe-Gly-Tyr-ProSer-NH2 (deltorphin C) 30:815 of Tyr-D-Ala-Phe-Gly-Tyr-ProThr([3-D-Glc)-Gly-NH2 30:815 of Tyr-D-Ala-Phe-Gly-Tyr-ProThr[I3-D-Glc(OAc)4]-Gly-NH2: 30:815 of Tyr-D-Ala-Phe-Thr(13-D-Glc)Tyr-Pro-Ser-NH2 30:815 of Tyr-D-Ala-P he- Thr( 13-D-G 1c )Val-VaI-Gly-NH2 30:815 Receptor tyrosine kinase (RTK) 25:512, 522,548 Receptor-like protein tyrosine phosphatases 27:874 [32/c~2Receptors 21:18 ~3132-Receptors 27:282 c~4132-Receptors 27:282 Receptors 27:363;30:421 and cell-cell adhesion 30:421 and cell-cell communication 30:421 antigenic determinants of 30:421 for bacteria 30:421 ofchiral proteins 27:363 with enzymatic activity 27:824 without enzymatic activity 27:825 Recombinant prourokinase (pro-UK) 30:839 as fibrinolytic enzymes 30:839 Recombinant tissue-type plasminogen activator 30:839 as fibrinolytic enzymes 30:839 Red wine 27:430 biological activity of 27:430 Redox enzymes 24:983-987,1003 enzymatic activity 24:983-987, 1003 Redox inhibitors 30:225 of 5-1ipoxygenase 30:225 Redox-based assays 21:511 Reductase inhibitory activity 21:590
1194 Refractory breast cancer treatment 24:933 taxol for 24:933 Relaxation 24:910-913 effect of cholecystokinin 24:910913 Renal cancer 23:294 Repandusic acid (hydrolysable tannin) 29:573 effects on HIV- 1 protease 29:573 Repellent properties 28:395 of Amblyomma variegatum 28:395 Reperfusion injuries 30:224 role of free radicals in 30:224 Reptoside 29:83 activity in EBV assay system 29:83 Rescorcinolic lipids 30:165-167 effects on enzymatic activity 30:165-167 interaction with proteins 30:165167 Reserpine 25:538 as immunosuppressive drug 25:538 Resistance-modifiers 30:595 antimalarial drugs as 30:595 Resistant Plasmodium species 30:595 in chloroquine sensitivity 30:595 Resorcinolic lipids 30:119,158,160,162164 as antifungal fluids 30:160 as growth reulators 30:162-163 as hair restoration-lotion 30:160 used in gingival infections 30:160 Resortive effect on progenitor cells 25:448,449 Respiration 23:375 coumarin effect on 23:335,356, 357,353,368,376,393,550,553 Respiratory ailments 24:847 Respiratory depression 30:799 due to analgesic alkaloid 30:799 Respiratory disorder 30:224 role of free radicals in 30:224 Respiratory infection 30:408
Respiratory syncytial virus 30:395 Respiratory toxins 24:1002,1063 Respiratory tract infections 26:50 Herniaria hirsuta in 26:50 Response decay mechanism 25:491 Response modifiers 23:129 biological 23"129 Resveratrol 27:430 biological activity of 27:430 Resveratrol 28:582 effects in LLC-bearing mice 28:582 effects on tumor volume 28:582 effects on tumor weight 28:582 Resveratrol oligomers 26:556-559 pharmacological properties 26:556-559 Retained placenta 30"597 treatment of 30:597 use of Hernandia moerenhoutiana in 30:597 use of Hernandia nymphaeifolia in 30:597 (+)-Reticuline 30:566,595,596 antimalarial activity of 30:595 antiplasmodial activity of 30:596 as platelet aggregation inhibitor 30:594 effect on antiplasmodial activity 30:596 Retinal 29:111;30:520,521 activity in AM bioassay system 29:111 in visual signal transduction 30:520 Retinoic acid 29:111 activity in AM, EBV, skin-1, ODC bioassay systems 29:111 Retinoic acid 30:493,498,521 in cell differentiation 30:521 in development 30:521 in growth regulation 30:521 Retinoid retinol 29:111 activity in AM, EBV bioassay systems 29:111 Retinoids 29:110 in mammary cancer 29:110 in urinary bladder cancer 29:110
1195
Retinol acetate 29:111 activity in AM bioassay system 29:111 Retinol palmitate 29:111 activity in AM bioassay system 29:111 Retroviral enzymes 30:397 inhibitor of 30:397 Retroviruses 30:394,397,408 causative agent of immunodeficiency syndrome 30:394 inhibitor of 30:408 Rett's disorder (RTT) 30:372,373,384 by mutations in MECP2 gene 30:373 genetic basis of 30:373 Reutericyclin 28:127 as antibiotic 28:127 Reverse transcriptase 30:226,395,397 role in HIV replication cycle 30:226 role in viral replication 30:397 Reversible inhibitors 7:40 glycosidase inhibitors as 7:40 Rhamnetin (3,5,3 ',4 '-tetrahydro xy- 7methoxyflavone) 29:578 effects on aminopeptidase N 29:578 Rhamnetin (7-O-methylquercetin) 29:581 effects on ACE 29:581 (-)-Rhazinilams 29:362 as microtubule poisons 29:364 Rheedia gardneriana 30:207 antinocicieptive effect of 30:207 Rheumatism 26:50 Herniaria hirsuta in 26:50 Rheumatism 30:192,691 use of non-steroidal antiinflammatory drugs (NSAIDs) 30:192 use of prostaglandin inhibitors 30:192 Rheumatoid arteriosclerosis 30:70 Rheumatoid arthritis 21:152;22:310; 26:170,486;30:70,204,225 in treatment of CPH82 26:170 in rats 30:204
reagent-induced 30:204 treatment of 30:225 use of Kalopanax pictus in 203 rHFPtase inhibitor 24:440 cembranolide as 24:439 Rhodiosin (flavonol glycoside) 29:589 effects on PEP 29:589 Rhoifolin (5, 4'-dihydroxy -7rhamnosyl-glucosyl-flavone) 29:573 effects on HIV- 1 protease 29:573 Rhombenone 24:456 FPTase inhibition by 24:456 Rice blast disease 1:404,529 Ricinoleic acid 30:193 analgesic action of 30:193 Rickettsial pathogens 28:394 Cowdria ruminantium as 28:394 Rifamycin-type macrolides 24:545,546 antiviral microbial-derived compound 24:545,546 Rift valley fever infection 30:411 treatment of 30:411 Rimantidine 27:108 for treatment of influenza in infections 27:108 Ritonavir 24:489 inhibitor of HIV-protease 24:489 RJ bioassay 30:807,814 activity of deltorphin B in 30:807 of glycopeptide 30:814 RNA virus 30:394 arenavirus type of 30:394 bunyavirus type of 30:394 coronavirus 30:394 influenza virus 30:394 measles virus 30:394 parainfluenza virus 30:394 picornavirus type of 30:394 rabies virus 30:394 reovirus type of 30:394 rotavirus type of 30:394 RNA-dependent RNA polymerase activity 30:407 virion-associated 30:407 RNA-directed DNA-polymerases 29:127 inhibition by Sf-9 cell line 29:33
1196
Robinin (Kaempferol 3-O-galactosylrhamnos yl- 7-O-rhamnos ide) (flavonol O-glycoside) 29:573 effects on HIV- 1 protease 29:573 Rocaglamide 16:565 antileukaemic activity of 16:565 Rofecoxib 30:192 as COX-2 inhibitor 30:192 Role 27:797 of cholecystokinin 27:797 of gastrin 27:797 of protein phosphorylation 27:821 Roridins 30:743 antiviral activity of 30:743 ROS Scavenging activity 22:317 of flavonoids 22:317 Rosiridin (monoterpene glycoside) 29:590 effects on PEP 29:590 Rosmanol (abietane diterpene) 29:575 effects on HIV- 1 protease 29:575 Rosmarinic acid (phenylpropanoid ester) 29:582 effects on collagenase 29:582 Rosmarinic acid (phenylpropanoid) 29:581 effects on ACE 29:581 Rotavirus gastroenteritis 30:406 treatment of 30:406 Rotaviruses 30:406 Rotenolone 28:436 as complex I inhibitor 28:436,437 Rotenone 28:436 as complex I inhibitor 28:436,437 Rotundifuran 29:101 activity in APO bioassay system 29:101 RT-PCR analyses 28:323 of tumor necrosis factor TNF-a 28:323 Rubella virus replication 30:374,409 autistic features in 30:374 blocking by 30:409 inhibitory effect on 30:409
Rubia tinctorum 26:675 mutagenic activity of 26:675 Rudivirus 30:409 Rupicolin B 29:90 activity in CRO assay system 29:90 Ruscogenin (triterpene) 29:587 effects on pancreatic ELA 29:587 Rutein 30:523 in human retina 30:523 Rutin 30:208,747 analgesic effect of 30:208 structure of 30:747 Rutin (quercetin 3-O-rutinoside; rutoside) (flavonol O-glycoside) 29:573 effects on HIV- 1 protease 29:573 Ryanodine receptor (RyR) 25:534,535 Ryanodine receptor Ca 2+ channels 25:535 Ryanodol-type diterpenes 26:852 insecticidal effects of 26:852, 1136 Sa mae sarn 28:574 antitumor activity of 28:574 as mild cathartic 28:574 Saffron (Crocus sativus L.) 28:313, 314,315 anti-tumor activity of 28:314,315 as coloring agent 28:313 uses in medicine 28:313 Saffamycin 10:78 antibacterial activity of 10:78 antitumor activity of 10:78 Saikosaponins 27:693 biological activity of 27:693 Salacia campestr& 30:639,667 cyclase activity of 30:639 Salacia krausii 30:667,693,694 against bilharziasis 30:693 against dysentery 30:693 Salicylic acid 27:63 elicitor of pathogen related genes 27:63 Salivary peptide P-C 24:906-909 from human saliva 24:906-909 inhibition of arginine induced
1197 glucagon release 24:909 potentiation of glucose induced in insulin release by 24:909 Salmonella mutagenicity assay 22:682 Salvia desoleana 26:416 antiinflammatory activity of 26:416 Salvia officinalis 26:402 antimicrobial activity of 26:402 Salvia sclarea oil 26:401 antimicrobial activity of 26:401 Sambucus nigra 30:407 antiviral activity of 30:407 Sandfly fever sicilian virus (SFSV) 30:410,412 phlebovirus type of 30:410 Sang-Bai-Pi 28:209 as herbal medicine 28:209 Sanggenol C 28:230 biological activity of 28:230 Sanggenol M 28:230 biological activity of 28:230 Sanggenon A 28:212,230 biological activity of 28:212,230 Sanggenon B 28:230 biological activity of 28:230 Sanggenon C 28:212,230 biological activity of 28:230 Sanggenon D 28:212 biological activity of 28:212 Sanggenon M 28:230 biological activity of 28:230 Sanguinarine 27:158,164,172,173, 177,178 biological activities of 27:178, 179 a,p-Santalol 29:91 activity in skin- 1, ODC assay systems 29:91 c~-Santonin 29:88 activity in CRG assay system 29:88 Sapargine 25:528 as immunosuppressive drug 25:528 SAPO 30 26:41 hemolytic activity of 26:41 SAPO 50 26:41 hemolytic activity of 26:41
Saponaria 26:55 of adjuvant activity 26:55 Saponaria officinalis 26:3,4,10,13,15, 18,27,30,42,54,57;30:407 anti-inflammatory activity of 26:27 antiviral activity of 30:407 Saponins 1:305;9:50-64,402;7:155,156, 190,426-432,434,435;18:649,650 molluscicidal activity of 7:427, 428 Saquayamycnis 24:480 FPTase inhibition by 24:480 Saquinavir 24:489 inhibitor of HIV- 1 protease 24:489 Saraine (cyclostellamine) 24:573,650, 651,660-662 Sarcoma-180 26:303 Sarcophaga bioassay 29:25 ajugasterone C activity in 29:28 amarasterone A activity in 29:28 amarasterone B activity in 29:28 cyasterone activity in 29:28 ponasterone A 2p-glucoside activity in 29:28 pterosterone activity in 29:28 rubrosterone activity in 29:28 sengosterone activity in 29:28 stachysterone C activity in 29:28 capitasterone activity in 29:28 Sarcophytol A 29:100 activity in EBV assay system 29:100 activity in colon-2 assay system 29:100 activity in liver-2 assay system 29:100 activity in lung-1 assay system 29:100 activity in mam-3 assay system 29:100 activity in pancr assay system 29:100 activity in skin-2 assay system 29:100 Sarcophytol B 8:18;29:100 activity in skin-2 assay system 29:100
1198
activity in mam-3assay system 29:100 antileukemic activity 8:18 Sarcoptes mites 28:410 cause of human scabies 28:410 symptoms of 28:410 Sarcoptes scabiei 28:409 cause of mange mites 28:409 cause of scabies 28:409 Sargasm horneri 30:400,405 anti-CMV activity of 30:405 polysaccharide (PS) from 30:400 Sarkomycin 8:150 as antitumor agent 8:150 Satratoxins 30:743 antiviral activity of 30:743 Savinin 13:653 as cytotoxic agent 13:653 O2-Scavenging acitivity 22:314,345 Scavenging activity 21:675;26:204 ofKrameria triandra 26:204 Scavenging effects 23:443 of tannic acid 23:443 SCH 207278 24:451 FPTase inhibition by 24:451 Schisandra 26:183 display platelet activating factor antagonist activity 26:183 effect on cardiovascular system 26:183 effect on heart rate 26:183 for treatment of hepatitis 26:183 Schisandrol A 26:245 as PAF-induced inhibitor 26:245 Schistosomiasis (Bilharzia) 7:405,408, 425,426,435 Schistosomicidal activity 1:545 Schizonticidal drug 26:837 Schizophrenia 21:101 ;25:531; 30:368,369,379 effect of circadian activity on 30:369 Scoparinol 29:101 activity in CRG bioassay system 29:101 from Scoparia dulcis 29:101 Scopoletin 5:515,520;7:117,120,204, 205,224
analgesic activity of 5:521 hypertensive activity of 5:521 SCR gene expression 25:387 Scropolioside A 29:84 activity in TPA assay system 29:84 Scrovalentinoside 29:84 activity in TPA assay system 29:84 Scutellaria baicalensis 30:55,56,69, 254,289 in allergric inflammatory disease 30:69 Scutellariae radix 27:431 biological activity of 27:431 SDB 21:695 inhibitory effect of 21:695 SDC 21:695 inhibitory effect of 21:695 SDZ-249-665 30:201 antinociceptive activity of 30:201 anti-hyperalgesic activity of 30:201 Seasonal affective disorder 30:369 effect of circadian activity on 30:369 Seaweeds 30:404 anti-CMV activity of 30:404 Secale cereale L. 27:125,216 allelopathic interaction of 27:125,216 13,14-seco- 13,14-Dioxoabiet- 13-en- 18oic acid 29:100 activity in EBV assay system 29:100 1,2-Secoemetine derivatives 6:485 amoebicidal activity of 6:485 Secoiridoids 26:330 antimicrobial activity of 26:330 Second messenger 25:516 Secondary metabolites 28:3,432,617 acaricidal activity of 28:432 biological activity of 28:617 Secondary metastatic tumor growth 30:64 effect of triterpenoids on 30:64 Secretory activity 21:98
1199 Sedative 22:513-514,599 arnica as 22:559 Artocarpus heterophyllus as 22:513 Basilicum polystachyon for 22:514 Sedative activity 21:673 Sedative in convulsions 22:518 Crocus sativus L. for 22:518 Sedative in epilepsy 22:535 Withania somnifera L. as 22:535 g-Selective agonist 30:807 dermorphin 30:807 8-Selective antagonist 30:806,811 Tyr-Tic-Phe-NH2 30:806 Selective antitumor activity 15:355 Selective cytotoxicity 13:648 8-Selective opioid agonist 30:817 deltorphin B 30:817 g-Selective opioid peptide 30:802 8-Selective opioid peptide 30:817 K/g-Selectivity 30:811 of 6N-cinnamoyl- [3-naltrexamine (CNX) 30:811 of ICI 19944 30:811 ofk opioids 30:811 8,g-Selectivity 30:819 in vivo 30:819 of glyco analogues 30:819 Self-inhibitors 9:230,231 bioassay of 9:230,231 biological activity of 9:222,237 (-)-Selin- 11-en-4(x-ol biological activity of 14:450,451 Semilicoisoflavone B 28:229 biological activity of 28:229 Semiochemicals 6:537-566 chiral synthesis of 6:537-566 synthesis of 8:219-256 Semisynthetic LSD 26:820 as psychodelic drug 26:820 (+)- S emivi o xanthin(9,10-dihydro xy- 7methoxy-naphtho-[2,3,c] pyran- 1 (1H)-one) 11:130 antibiotic activity of 11:130 antifungal activity of 11:130 Sendai virus infection 30:412
Sensory neurons 30:194 hyperpolarisation of 30:194 8er264 inhibitors 26:368 Serine 27:850 activitiy of 27:850 Serine 30:836 c~2-macroglobulin inhibition by 30:836 Serine protease inhibitor proteins 29:617 arrowhead PIs API-A & API-B as 29:617 Brassica BN as 29:618 Brassica TIBN as 29:618 Cassia defensin PI as 29:617 Cp-thionin as 29:617 effects on barley malt cysteine endoproteinases 29:617 effects on chymotrypsin 29:617 effects on subtilisin 29:618 effects on subtilisin ((x-amylase inhibitors) 29:617 Eleusine double-headed TRY-~xamylase inhibitor I-2 as 29:617 from Brassica nigra 29:618 from Brassica napus 29:618 from Cassia fistula 29:617 from Eleusine coracana 29:617 from Hordeum vulgare 29:617 from Phaseolus angularis 29:617,618 from Sagittaria sagittifolia 29:617 from Sinapis arvensis 29:618 from Vigna unguiculata 29:617 Hordeum lipid transfer proteins as 29:617 Phaseolus Defensin PI as 29:617 Phaseolus LTP PI as 29:618 Serine proteases 29:570;30:70,830, 832,833,840 blood clotting factors as 29:570 cathepsin G as 29:570 chymase as 29:570 chymotrypsin as 29:570 granzymes as 29:570 in angiogenesis 29:570 in blood clotting 29:570
1200
in cytosolic proteolysis 29:570 in digestion 29:570 in inflammation 29:570 in proprotein processing 29:570 in tissue remodelling 29:570 kallikrein as 29:570 plasmin as 29:570 prolyl endopeptidases as 29:570 role in blood coagulation 30:70 role in platelet activation 30:70 role in pulmonary vascular injury 30:70 subtilisin as 29:570 thrombin as 29:570 trypsin as 29:570 tryptase as 29:570 urokinase type plasminogen activator as 29:570 Serine proteases (subtilases) 25:388 cysteine proteinase inhibitor 25:370 poly phenol oxidase 25:370 serine proteinase inhibitor II 25:370 Serine proteinase inhibitor I 25:370 as defense proteins 25:370 Serine proteinase inhibitor II 25:370 Serine receptor 27:824 Serine-threonine-specific receptor protein kinases (S/T-RPKs) 25:520 Serotonergic innervations 30:377 autoradiographic imaging 30:377 in cerebral cortex 30:377 in neonatal rats by immunohistochemical techniques 30:377 physiological role of 377 Serotonergic neurons 30:368,376 in raphe nuclei 30:376 role in 30:regulation of neurogenesis 30:368 Serotonergic neurotransmission 30:368 abnormalities of 30:368 effect on behavioral dysfunction 30:368 effect on neuronal differentiation 30:368 effect on proliferation 30:368 effect on synaptogenesis 30:368 Serotonergic receptors 21:68;22:21
Serotonin 22:111,668,669,673; 30:367,368,369,376,377,378,379, 381,384,627 as hyperforin inhibitor 30:627 as neurotransmitter 30:367 effect on synaptogenesis 30:378 in apoptosis 30:367 in cell proliferation 30:367 in presynaptic neuron 30:381 morphogenic properties of 30:367 neurochemical connection of 30:368 receptor activity of 30:379,382 role in anxiety 30:3.68 role in austism 30:368 role in brain processes 30:367 role in depression 30:368 role in human mood 30:368 role in hypertension 30:368 role in irritable bowel syndrome 30:368 role in mental disorders 30:368 role in migraine 30:368 role in obsessive-compulsive disorder 30:368 role in panic disorder 30:368 role in pathological anxiety 30:376 role in schizophrenia 30:368 role in social interaction 30:368 role in social phobia 30:368 Serotonin (5-HT) receptors 30:376,378, 382,383 in brain 30:383 in limbic brain regions 30:383 pharmacological aspects of 30:378 Serotonin (5-HT) re-uptake inhibitors 30:368 mechanism of 30:368 Serotonin (5-HT) synthesis 30:370,376, 377 in autistic children 30:377 Serotonin (5-HT) 1AR receptor antagonists 30:378 in posmatal treatment 30:378 Serotonin (5-HT)sA receptor 30:375 in brain development 30:375
1201
in phenotypic behavioral irregularities 30:375 in purkinje cells 30:375 mRNA expression of 30:375 Serotonin action 30:378 on apoptosis 30:378 on maturation 30:378 on neuronal functioning 30:378 on proliferation 30:378 Serotonin agonists 25:531 anticomplementary activity of 25:46 role of cyclic AMP-dependent protein kinase 25:46 delayed-type allergy suppressant activity of 25:46 induced edema 25:46 Serotonin induced edema 25:46 Serotonin receptor 25:530 type of G-protein-linked receptor 25:530 Serotonin receptors 25:531 Serotonin secretion 12:390 inhibition by K-252a 12:390 Serotonin synthesis inhibitor 30:378 parachlorophenylalanine as 30:378 Serum ALT activity 25:471,476 of sweroside 25:471,476 of Colchicum autumnale 25:473 Serum TC 27:420 biological activity of 27:420 Serum transaminase 27:415,417,420 biological activity of 27:415, 417,420 Serum transaminase activity 25:469 of Curcumia longa L. 25:469 Serum triglyceride 27:404 biological activity of 27:404 Serum tumor necrosis factors (TNF-a) 25:459 Sesquiterpene lactone 7:426;8:195-201 molluscicidal activity of 7:427 Sesquiterpene quinones 5:429 antimicrobial activity of 5:429 cytotoxic activity of 5:429 Sesquiterpenoids drimane-type synthesis 29:127
avian myeloblastosis virus (AMV) inhibition by 127 by Jauch 29:127 Sex pheromone 6:537-546 synthesis of 6:537-546 Sexual potency 28:4 ofbroussoflavonol G 28:4 sGOT 30:292 activities of 30:292 sGPT 30:292 activities of 21:654;30:292 Shaagrockol B 28:675 anifungal activity of 28:675 Shigella flexnert 14:233 O-antigenic polysaccharide from 14:233 Shikimic acid 10:45;11:182-191 antibiotics 11:182-191 (+)-Shikimic acid derivatives 29:478 antitumoral activity of 29:479 Shinpterocarpin 28:229 biological activity of 28:229 Sialic acids 27:103 biological function of 27:103 model for 27:111 Sialyltransferase activity 16:81 Side effect 30:194,799 of analgesic alkaloid 30:799 of opioids 30:194 Sigmoidin A 28:229 biological activity of 28:229 Sigmoidin B 28:229 biological activity of 28:229 Signal reception 30:377 in autistic children 30:377 Signal transduction mechanisms 25:518 Signal transduction pathways 25:514, 515 Signal transductors/activators of transcription (STATS) 25:519 Silandrin 26:255 as antihepatotoxic agent 26:255 Silchristin 26:255 as antihepatotoxic agent 26:255 Sildenafil 30:155 used for erectile dysfunction 30:155 Silybin 26:255 as antihepatotoxic agent 26:255
1202
Silydianin 26:255 as antihepatotoxic agent 8:166; 26:255 Silymonin 26:255 as antihepatotoxic agent 26:255 Simocyclinon 29:319 antibiotic activity of 29:319 cytostatic effects of 29:319 Sindbis virus 17:135;26:223 Sinefungin 24:547 antiviral microbial-derived compound 24:547 Sinomenine 25:472,476 hepatoprotective effect of 25:472 Sitoindoside II 26:219 as chemopreventive agent 26:219 13-Sitosterol-3-O-13-D-glucoside (phytosterol glycoside) 29:590 effects on PEP 29:590 Skin cancer 5:747 Skin diseases 30:732 Skin inflammation 30:323 anthrones used for 30:323 SKK Moth 1:704-706 juvenile hormone from 1:704706 (-)-Slaframine 18:386 activity of 12:306 Slaframine 27:252 biological activity of 27:252 Slaframine alkaloids 27:250,255 as muscarinic agonist 27:255 Sleeping sickness 2:293,302 Small cell lung cancer 27:799,802 Smenoquinone 5:434,425 antimicrobial activity of 5:434, 425 Smenorthoquinone 5:431,432;15:291, 292 antimicrobial activity of 5:434, 435 Smenospongine 5:434,425 antimicrobial activity of 5:434, 435 cytotoxic activity of 5:435 Smooth muscle contraction 24:875-925 of Kampo medicines 24:875-926
Smooth muscle relaxation 24:875-925 as biological action 24:875 of Kampo medicines 24:875-926 Snake bite 30:691 treatment of 30:691 use of Crossopetalum gaumeri 30:691 Sobrerol 29:83 activity in mam-2 assay system 29:83 activity in GST assay system 29:83 activity in RAS assay system 29:83 Social phobia 30:368 role ofserotonin (5-HT) 30:368 Sodium salt of caffeic acid tetramer 24:742,743 anti-HIV activity of 24:742 Soilborne fungi 21:181 bioactive metabolites from 21:181 Soilborne phytopathogens 21:182 biological control of 21:182 Solandelactones 24:455 FPTase inhibition by 24:455 Solanidane-induced teratogenicity 23:573 Solid tumors neovasularization 25:593 Somatostain 25:265 as A~ adenosine agonists 25:265 Somatostatin analog 27:795,796 Somatostatin receptor 21:72;22:26; 25:530 type of G-protein-linked receptor 25:530 Sonodione 30:566 from Hernandia sonora 30:566 Sores 30:616 tricyclic acylphloroglucinols in 30:616 Sorivudine 24:474,486 as anti-viral agent 24:474,486 Sorocein F 28:230 biological activity of 28:230 SOS chromotest 22:623 Soyabean saponins 25:222,223 hypocholesterdemic effects of 25:222
1203
Soyasaponins 27:398 anti-obesity action of 27:398 biological activity of 27:399 Soybean trypsin inhibitor (SBTI) 30:843,836 Spasm 22:524 Ledebouriella seseloides for 22:524 Spasmogenic 24:799 biological activity 24:799 Spasmolytic 24:799 biological activity 24:799 Spasmolytic activity 23:358 ;28:257,293; 30:264,561,748 of Hernandia moerenhoutiana 30:561 ofHernandia voyronii 30:561 of imperatorin 23:350,358 of plant polyphenols 28:257,293 of Thymus satureioides 30:264 on guinea pig ileum 30:748 on smooth muscles 30:264 Spasmolytics 17:395 Spasms 22:522 Hedeoma pulegioides L. for 22:522 Spatol 6:39 biological activities of 6:39 (-)-Specionin 10:425 antifeedant activity of 10:425 Spermicidal activity 26:53 of Gypsophila paniculata 26:53 Sphingolipid receptor Ca 2+ channels 25:535 Sphingolipid receptors 25:534 Sphinxolide 10:153;17:17 antitumor activity of 17:17 Spider mite 1:702 hatching inhibitor 1:702 Spiroalkyl analogs 28:357 biological activity of 28:357 Spirulina platensis 30:399,404,408 anti-influenza activity of 30:408 biological activity of 30:404 calcium spirulan from 30:399 polysaccharide (PS) from 30:408 Spleen/adipose tissue weight 30:56,57, 66
effect of fucoidan on 30:56,57 effect of oleic acid on 30:65 Spontaneous apoptosis 26:926 Spontaneous metastasis 25:440 Squarroside A 26:31,50 immuno-modulatory effect of 26:31 from Vaccaria segetalis 26:50 Squash family serine protease inhibitors 29:614 BD-TI-II as 29:614 CMTI-I as 29:614 CMTI-III as 29:614 CMTI-IV as 29:615 CPGTI-I as 29:615 CPTI-II as 29:615 CSTI-IIb as 29:614 Cucumis CMCTI-I as 29:614 Cucumis CMeTI-A as 29:614 CVTI- 1 as 29:614 Ecballium EETI-II as 29:615 effects on cathepsin G 29:615 effects on elastase 29:615 effects on endopeptidase 29:614 effects on factor Xa, factor XIIa, kallikrein, trypsin 29:615 effects on lysyl endopeptidase 29:614 effects on trypsin 29:614 effects on trypsin 29:615 effects on trypsin 29:616 effects on Xa, XIIa, kallikrein, plasmin, trypsin 29:614 ELTI-I as 29:615 from Bryonia dioica 29:614 from Citrullus vulgaris 29:614 from Cucumis melo 29:614 from Cucumis melo 29:614 from Cucumis sativus 29:614 from Cucurbita maxima 29:614 from Cucurbita maxima 29:614 from Cucurbita pepo 29:615 from Cucurbita pepo 29:615 from Ecballium elaterium 29:615 from Echinocystis lobata 29:615 from Lagenaria leucantha 29:615 from Luffa acutangula 29:615
1204
from Luffa cylindrica 29:615 from Momordica charantia 29:615 from Momordica charantia 29:615,616 from Mornordica cochinchinensis 29:616 from Mornordica repens (Cucurbitaceae) 29:616 from Tricosanthes 29:616 HMTI-I as 29:614 LATI as 29:615 LATI-II as 29:615 LLDTI-I as 29:615 LLDTI-II as 29:615 MCEI-I as 29:615 Stachenol 29:101 activity in EBV bioassay system 29:101 Stachenone 29:101 activity in EBV bioassay system 29:101 Standishinal 29:100 activity in EBV assay system 29:100 Standishinal diacetate 29:100 activity in EBV assay system 29:100 Staphyllococcus aureus 30:693 minimal inhibitory concentration (MIC) of 30:693 Staphyllococcus epidermidis 30:693 minimal inhibitory concentration (MIC) of 30:693 Staphyllococcus saprophyticus 30:693 minimal inhibitory concentration (MIC) of 30:693 Staphyllococcus warnieri 30:693 minimal inhibitory concentration (MIC) of 30:693 Staphylococcal mammary infection 23:137 in ewes 23:137 Staphylococcus aureus 30:628,739 antibacterial activity against 30:739 antibacterial properties of 30:628 antifungal activity against 30:739
Starfish fertilisation inhibitor 28:712 callyspongin B as 28:712 Stavudin 24:474,486,488 as anti-viral agent 24:474,486, 488 Steganes 29:360,399 cytotoxicity of 29:360,399 tubulin assembly inhibition by 29:360 antitubulin activity of 29:399,400 microtubules assembly inhibition by 29:399 Sterculia urens Roxb. 30:405 antiviral activity of 30:405 Steroid hormones 27:823 Steroid saponins 7:426;15:27-29 molluscicidal activity of 7:427 Steroidal amines 7:16-24 teratogenic metabolites of 7:2124 toxic 7:16-24 Steroidal lactones 14:439,20:135-148 cardiac active steroids 14:439 Steroids 24:510-521,533-540 as antiviral compound 24:510521,533-540 Sterol biosynthesis 25:303 inhibitor of 25:303 6a-Sterol sulfate 28:702 cytotoxicity against 28:702 Sterol sulfates haplosamate A 28:703 as HIV-1 integrase inhibitor 28:703 Sterols 25:43 antitumor activity of 25:43 antiinflammatory activity of 25:43 Stevia 27:299-317 acute toxicity tests of 27:307 allergenicity problems of 27:315 chronic toxicity studies of 27:306-308 effect on fertility 27:309,310 safety evaluation of 27:299-317 subacute toxicity studies of 27:307,308 Stevia extract 27:307,310,314 for diabetics 27:314
1205
Stevia leaves 27:315 immunological activity of 27:315 Stevia plant 27:315 allergenic activity of 27:315 Steviol 27:304,305,307,312 acute toxicity tests of 27:307 effect on fertility 27:312 mutagenicity tests with 27:304 Stevioside 27:8,9,13,22,299-317;29:101 activity in TPA bioassaysystem 29:101 activity in skin-1 bioassay system 29:101 acute toxicity tests of 27:307 allergenicity problems of 27:315 chronic toxicity studies of 27:306,307,308 effect on fertility 27:309,310 for phenylketonuria 27:315 mutagenicity tests for 27:303,304 subacute toxicity of studies of 27:307,308 Stigmasterol 30:208,505,570,719 analgesic effect of 30:208 Stilbene derivatives 27:405,409;28:579 biological activity of 27:405,409 in LLC-bearing mice 28:579 tumor growth inhibition by 28:579 Stimulatory 24:845 biological activity 24:845 Stimulant agent 23:642 ofteucrium sp. 23:642 Stimulus-response mechanisms 25:515 Streptococci 29:535 pathogenicity of 29:535 serological groups of 29:535 Streptokinase/streptodomase 25:271 Streptolygidin 28:130 antibiotic activity of 28:130 as bacterial RNA polymerase 28:inhibitor 130 as terminal DNA transferase 28:inhibitor 28:130 Striga asiatica 30:162 infection with 30:162
Structural-functional activity relationship 23:108 Structure activity relationship 21:21, 262,284,578,661,665,666 ofbioactive metabolites 21:251 of scopadulan-type diterpenoids 21:717 Structure activity relationship studies (SAR) 30:195,494,800 of anandamide 30:196 of aspirin 30:195 ofopioid analogues 30:800 of vitamin D analogues 30:493 Structure dereplication 29:658 bioactive natural product database in 29:670 of melanin inhibition 29:664 Structure-activity profile 12:220,221 oftaxol 12:220,221 Structure-antioxidant activity relationship 23:773 Structure-function relationship 21:21, 50,84 Strychnine 25:530 as immunosuppressive drug 25:530 Strychnopentamine 26:1062 anticancer activity of 26:1060 Strychnos bisindole 26:1062 anticancer activity of 26:1060 Strychnos monoindole 26:1061 anticancer/protozoal 26:1061 Subacute toxicity 27:307 from animals 27:307 of stevioside 27:308 Subcutaneous Pentylenetetrazole Seizure threshold test (ScPTZ) 22:508 Substituted benzo[c] phenanthridines 4:544 in cancer chemotherapy 4:544 5,6-Substituted tetralin 8:396 ct-adrenergic activity of 8:396 Succinate ubiquinone oxydoreductase inhibitions 26:924 Succinoyl-andrographolide 29:588 effects on furin 29:588 SUDHL-4-1ymphoma 21:138 Sugar cane cystatins 29:593
1206
effects on cysteine proteases 29:593 Suicide inhibition 27:348 of 8'-hydroxylase 27:348 Suicide inhibitors 9:593;27:347 for abscisic acid 8'-hydroxylase 27:347 Suicide substrates (irreversible inhibitors) 7:36-40 34-Sulfatobastadin 13 28:695 as endothelin A receptor inhibitor 28:695 Sulfide-containing pyrroloiminoquinones 28:685 as antileukaemic agents 28:685 Sulfur-containing cyclic peptides 28:678 biological activities of 28:678 cytotoxicity of 28:678 Sulphated polysaccharide (PS) 30:398, 400,405 anti-CMV activity of 30:405 anti-HIV activity of 30:398 antiviral activity against HIV 30:400 effect on viral replication 30:400 from marine sources 30:400 inhibitory effect of 30:398 mechanisms of action of 30:400 Sulphated polysaccharide (PS) extracts 30:399 inhibitory activity of 30:399 Sulphonylurea drugs 25:534 Sunflower cystatin phytocystatin 29:593 effects on cathepsin H ficin 29:593 effects on papain 29:593 Sunflower multicystatin 29:593 effects on papain 29:593 Supercritical fluid extraction 21:576 Superoxide dismutase 25:931 Superoxide dismutase activity 21:669 Suppressing activity 30:308 on cells proliferation 30:308 Suppurative dermatitis 22:607 use of Platycodon grandiflorum in 30:88
Susceptible Burkitts lymphoma (BL) 25:272 apoptosis in 25:272 Suspensaside 5:513 antihypertensive activity of 5:513 Suvanine 28:670 as acetyl cholinesterase inhibitor 28:670 Swainsonine 7:32,44,112;27:252,253, 255,524,525 biological activity of 27:252 from gastrointestinal tract 27:525 immunomodulation by 7:16 inhibition (+)-ramannosidase by 27:255 inhibition cellular mannosidases by 27:252 inhibits naranginase 27:255 et-mannosidase inhibition by 7:11 Sweet taste 27:10,11 activation by receptorindependent mechanism 27:12 receptor for 27:11 Sweetness inducers 27:39,40 arabinogalactin as 27:39 caffeic acid conjugates cynarin as 27:39 chlorogenic acid as 27:39 curculin as 27:39 miraculin as 27:39 strogin 1 as 27:39,40 strogin 2 as 27:39,40 strogin 4 as 27:39,40 Sweetness inhibitors 27:40-43 altemoside I as 27:41 altemoside II as 27:41 altemoside III as 27:41 altemoside IV as 27:41 altemoside V as 27:41 from Gymnema alternifolium as 27:40 from Gymnema sylvestre as 27:40-43 from Hovenia dulcis Thumb. as 27:40 from Stephanotis lutchuensis
1207 var. japonica as 27:40 from Ziziphosjujuta P. Miller as 27:40 gymaemasaponin III as 27:41,43 gymaemasaponin IV as 27:41,43 gymaemasaponin V as 27:41,43 gymnemic acid I as 27:41,42 gynmemlc acid II as 27:41,42 gymnemlc acid III as 27:41,42 gymnemlc acid IV as 27:41,42 gynmen~c acid IX as 27:41,42 gymnemlc acid V as 27:41,42 gymnermc acid VI as 27:41,42 gymnemlc acid VIII as 27:41,42 gymnemlc acid X as 27:41,42 gymnermc acid XI as 27:41,42 gymnen~c acid XII as 27:41,42 gymnemlc acid XIII as 27:42,42 gynmemlc acid XIV as 27:41,42 gymnemlc acid XV as 27:41,42, 45 gymnemic acid XVI as 27:41,42, 45 gymnemic acid XVII as 27:41, 42,45 gymnemic acid XVIII as 27:41, 42,45 hoduloside I as 27:41 hoduloside II as 27:41 hoduloside III as 27:41 hoduloside IV as 27:41 hoduloside IX as 27:41 hoduloside V as 27:41 hoduloside VII as 27:41 hoduloside VIII as 27:41 hoduloside X as 27:41 hovenoside I as 27:41 jujubasaponm II as 27:41 jujubasaponm III as 27:41 jujubasaponln IV as 27:41 jujubasaponln V as 27:41 jujubasaponm VI as 27:41 jujubasaponin zizyphus saponin III as 27:41 jujuboside B as 27:41 saponin C2 as 27:41 saponin E as 27:41 saponin H as 27:41 sitakisoside XIII as 27:41
sitakisoside XVI as 27:41 sitakisoside XVIII as 27:41 sitakisoside I as 27:41 sitakisoside II as 27:41 sitakisoside III as 27:41 sitakisoside IV as 27:41 sltakisoside IX as 27:41 sltakisoside V as 27:41 sltakisoside VI as 27:41 sitakisoside VII as 27:41 sitakisoside VIII as 27:41 sitakisoside X as 27:41 sltakisoside XI as 27:41 sltakisoside XII as 27:41 Ziziphin as 27:41 Zizyphus saponin I as 27:41 Zizyphus saponin II as 27:41 Sweroside 25:471,476 serum ALT activity of 25:471, 476 Symbiotic marine microorganisms 23:185 bioactive metabolites 23:185 Sympathetic ganglia 30:782 blockade of 30:782 Sympathetic nerve activity 30:787 Sympathomimetic amines 12:411 Synapic potential mediation 28:318 by non-NMDA receptors 28:318 Synaptic actions 30:381 of serotonin 30:381 Synaptic dopamine transporters 25:539 Synaptic glycine transporters 25:539 Synaptic serotonin transporters 25:539 Synaptogenesis 30:368,377 effect of serotonergic neurotransmission on 30:368 role in rodents 30:377 role of serotonin in 30:377 Syndrome type-lA 26:1130 adipose tissue distribution as 26:1130 cerebellar dysfunction as 26:1130 liver insufficiency as 26:1130 peripheral neuropathy as 26:1130 psychomotor retardation as 26:1130
1208
Synergistic activity 21:673 Synergistic effect 21:608,611; 30:498,596 ofhervelines B 30:596 ofhervelines C 30:596 of retinoids 30:498 of vitamin D derivatives 30:498 Synergistic interaction 21:698 of acyclovir(ACV) 21:698 ofganciclovir (GCV) 21:698 with ganciclovir (GCV) 21:698 Synergistic purgative actions 30:306 of rheinanthrone 30:306 of aloe-emodin-anthrone 30:306 Synthetic pharmacological agents 30:224 antioxidant activity of 30:224 Synthetic podolactones 28:484 allelopathic activity of 28:484 Synthetic psychotropic agents 24:1093 Syringaresinol 24:741 anti-platelet aggregation activity of 24:741 (-)-Syringaresinol 26:243 as PAF-induced inhibitor 26:243 Systemic acquired resistance (SAR) 25:40,394 Systemic wound response protein 25:402 Systemin activity 25:373 assay for 25:373 T-2 toxin 13:522 from Fusarium sporotrichioides 13:522 Tabernanthine 25:533 as immunosuppressive drug 25:533 Tachykinin 9:318 Tail flick test 30:802,810 for determination of antinociception 30:802 of deltorphin II 30:810 of DTAOH+DEL II 30:810 of DTOH+DEL II 30:810 Taiwanin E 26:243 as PAF-induced inhibitor 26:243
Taiwanin E methyl ether 26:243 as PAF-induced inhibitor 26:243 Tamoxifen 26:222 Tanacetum parthenium 24:849 active anti-migrane principle in 24:849 Tanacetum parthenium 30:206 in treatment of migraine 30:206 Tanacetum species 27:547-594, 634-637,639,641,643 allergent activity of 27:634 anticoagulant activity of 27:635 antifibrinolytic activity of 27:635 antihelmintic activity of 27:636 antiinflammatory activity of 27:637 antiulcer activity of 27:639 biological activities of 27:547 cytotoxic effects of 27:639 insecticidal activity of 27:641 phytochemical studies of 27:548-594 phytotoxic activity of 27:643 prophylactic activity against migraine 27:643 Tanacetum vulgare's extracts 28:427 acaricidal activity of 28:427 Tangeretin (5,6 " 8,4'-pentahydroxyflavone) 29,.~73 effects on HIV- 1 protease 29:573 Tannins 24:510-521;27:413,416 as antiviral compound 24:510521 biological activity of 27:413,416 Tanshione I 29:100 activity in AM assay system 29:100 Tar cancer 7:8 Taraxacum officinale Wigg 27:215 allelopathic interaction of 27:215 Taraxerol (taraxer- 14-en-3 [3-ol) 29:588 effects on TRY 29:588 Taste principles 2:278-280 hot and bitter 2:278-280 Taste receptors 29:42
1209
Tauropinnaic acid 28:657 as phospholipase A2 inhibitor 28:657 Taurospongin A 28:690 as DNA polymerase inhibitor 28:690 as HIV reverse transcriptase inhibitor 28:690 Taxane 11:4-6 biological activity of 11:4-6 Taxifolin (dihydroflavonol) 29:583 effects on MMP 29:583 Taxifolin 3- O-ot-L-rhamnopyranoside 28:64 anti-oxidant activity of 28:64 Taxisol 28:559 as anticancer drug 28:559 Taxodione 19:405,20:712 biological activity of 14:667 Taxol 12:179,180;24:269,271,276,405, 933-972;30:5 antitumor activity of 12:180 as microtubule stabilizing agent 30 biological activity of 12:179,180 for treatment of ovarian cancer 24:933 for treatment of refractory breast cancer 24:933 Taxol-resistam breast cancer 30:5 clinical development for 30:5 chemotherapeutic agent for 30:5 Taxol-resistant colon cell 30:5 Taxol-resistant ovarian cell 30:5 Taxotere 12:179,180 biological activity of 12:179,180 T-cell activation 25:463 T-cell mediated cytotoxicity 25:466 T-cell mediated liver injury 25:463 T-cell stimulation 23:129 T-cell subsets 25:442 antitumor-effect of 25:442 y6-T-cells 30:766,768 in CVE-administered mice 30:768 in protection after listerial infection 30:766
Tea 30:80 effect on lipids (total cholesterol triglyceride) 30:80 Tea saponin 30:84,86 effect on pancreatic lipase activity 30:86 effect on parametrial adipose weight 30:85 effect on triacylglycerol contents 30:84 Tea tree (Melaleuca alternifolia) 28:415 activity against Psoroptes cuniculi 28:415 Tenuazonic acid 28:114 antibacterial activity of 28:115 antiviral activity of 28:115 as growth inhibitor 28:115 for peptide inhibition 28:115 Tenuifolin B 28:229 biological activity of 28:229 Tephrosin 28:436 as complex I inhibitor 28:436, 437 Teratogenic agents 23:563 Teratogenic metabolites 7:21-24 of steroidal amines 7:21-24 Teratogenic potencies 23:575 of steroidal alkaloids 23:575 Teratogenicity 7:19-22,24;23:576, 577,584 ofjervanes 23:576,577,584 of solanidanes 23:576,577,584 of spirosolanes 23:576,577 Terferol 29:265 as acetylcholinesterase (AchE) inhibitor 29:265 Termite soldiers 14:451 defensive secretion of 14:451 Terpenes 5:403;7:208-219;8:219;17:4, 15,613,642;24:510-521 ;29:74,76 anti-inflammatory activities of 29:74,81 anti-mutagenic activity of 29:76 apoptosis induction by 29:76 as antihealants 14:451 as glues 14:451 as irritants 14:451 as repellents 14:451 bioactives of 29:74
1210 chemopreventive activities of 29:74,81 ear edema inhibition by 29:76 effects on 5-1ipoxygenaseenzyme 29:76 effects on 7,12-dimethylbenz [a]anthracene (DMBA) induced mammary tumors 29:76 effects on activated protein 1 (AP- 1) activity 29:76 effects on active oxygen species formation 29:76 effects on azoxymethane induced colon tumors 29:76 effects on cellular differentiation 29:76 effects on cyclooxygenase (COX) enzyme 29:76 effects on cytochrome P450 (CYP) enzyme 29:76 effects on Epstein-Barr virus earlyantigen (EBV-EA) activation 29:76 effects on glutathione formation 29:76 effects on glutathione peroxidases enzyme 29:76 effects on glutathione-Stransferase induction 29:76 effects on hepatic tumors 29:76 effects on inducible NO synthase enzyme 29:76 effects on mammary DMBADNA adduct 29:76 effects on MU induced mammary tumors 29:76 effects on pancreatic tumors 29:76 effects on pulmonary tumors 29:76 effects on TPA-induced EBV activation 29:113 effects on transcription factor (NF-AT) induction 29:76 effects on UVB-induced AP-1 transactivation 29:76 gastric carcinogenesis inhibition by 29:76
in bioassay systems 29:74 inhibitory effects of 29:113 Terpenoids 24:533-540 as antiviral compound 24:533540 Terphenyllin 29:267 against sea urchin (Hemicentrotus pulcherrimus) embryos 29:268 against Staphylococcus aureus 29:269 analogues as drug 29:270 antioxidant activity of 29:269 as plant growth inihibitor 29:268 cytotoxicity of 29:268,269 effects on cell proliferation 29:268 effects on wheat coleoptile growth 29:268 genotoxicity of 29:269 mutagenicity of 29:269 peroxidation inhibition by 29:269 scavenging effects on ct,ctdiphenyl- p-picrylhydrazyl (DPPH) radicals 29:269 p-Terphenylquinones 29:263 antibacterial activity of 29:264 anti-inflammatory activity of 29:264 anti-insect activity of 29:264 antioxidant activity of 29:264 as atromentin 29:263 as fungal pigments 29:263 as polyporic acid 29:263 cytotoxic activity of 29:264 Terphenyls as DPPH radical scavengers 29:274 as PEP inhibitors 29:277 atromentin as 29:271 aurantiacin as 29:272 curtisian A-D as 29:274 2,3-diacetoxy-4',4",5,6tetrahydroxy-p-terphenyl as 29:274 3,6-dibenzoylatromentin as 29:272 flavomentins A - D as 29:272 from Boletopsis grisea
1211
(Polyporus griseus) 29:277 from Paxillus atrotomentosus var bambusinus 29:273,274 from Polyozellus multiplex 29:277 from Thelephora ganbajun 29:272,274 functions of 29:271 ganbajunin A as 29:272 ganbajunins C-G as 29:274 in Alzheimer's disease 29:277 leuco-atromentin as 29:273 leucomentins as 29:273 polyozellin as 29:277 thelephorin A as 29:274 Terphenyls bearing seven oxygenated functions 29:277 against gram-positive bacteria 29:278 cycloleucomelone as 29:278 cytotoxicity data for 29:278 Terpinen-4-ol 29:83 activity in AM assay system 29:83 from Melaleuca altemifolia 29:83 (x-Terpinene 29:83 activity in AM assay system 29:83 7-Terpinene 29:83 activity in AM assay system 29:83 (x-Terpineol 28:406;29:83 acaricidal property of 28:406 activity in RAS assay system 29:83 4-Terpineol 28:426 as bioactive monoterpenoid 28:426 Terpinolene 29:83 activity in AM assay system 29:83 Terprenins 29:270 against human leukaemia 29:271 against human lung cancer 29:271 against mouse spleen lymphocytes 29:271
antiproliferative activity of 29:271 as antiallergic drugs 29:271 effects on antigen-specific IgE production 29:271 effects on pyrimidine biosynthesis 29:271 Testosterone 25:419,516 Tetracyclines 29:312 anhydrotetracycline as 29:312 as halogen acid antibiotics 29:312 for anthrax 29:312 for bacterial pneumonia 29:312 for brucellosis 29:312 for louse-borne typhus 29:312 for lymphogranuloma 29:312 for pertussis 29:312 for rickettsioses 29:312 for scarlet fever 29:312 for tularemia 29:312 for viral diseases trachoma 29:312 resistance to 29:312 12-O-Tetradecanoylphorbol 13-acetate (TPA) 30:592,593,695 as tumor-promotion agent 30:592 in vitro bioassays of 30:592 inhibition of 30:695 role in tumor-promotion 30:593 Tetradotoxin 21:73 Tetrahydroanthracenes (vismiones) 7:418-420 antiproliferative activity 7:419 Tetrahydrocannabinol 7:7 psychotropic activity of 7:7 A9-Tetrahydrocannabinol 30:195 as natural analgesic product 30:195 A6-Tetrahydrocannabinol (THC) 30:194 as analgesic 30:194 in migraine 30:194 pharmacological properties of 30:195 pharmacological studies of 30:194
1212
Tetrahydroswertianolin (THS) 25:467 hepatoprotective activity of 25:467 5,6,13,14-Tetrahydroxy- 1,2,9,10 tetrahydro- 1,9-epoxydibenzo [a,e] cyclooctene 30:227 role in HIV-1 IN inhibitor activity 30:227 2,4,2 ',4 '-Te trahydroxy- 3 'prenylchalcone 28:16 aromatase inhibition by 28:16 5,7,2',4'-Tetrahydroxy-3-geranylflavone 28:17 aromatase inhibition by 28:17 1,3,5,7-Tetrahydroxy- 8- is oprenylxanthone 29:571 Candida albicans aspartic protease inhibition by 29:571 (2S)-5,7,2',4'-Tetrahydroxyflavanone 28:17 aromatase inhibition by 28:17 Tetrahydroxypavinan 30:225 effect on 5-1ipoxygenase inhibition 30:225 3,4,3 ',4'-Tetramethoxylignan-7-ol 26:228 antifungal activity of 26:228 Tetramic acid 28:109,110 biological activity of 28:110 Tetramic acid antibiotics 14:97-141 biological activity of 14:107-110 Tetramic acid-containing compounds 28:109 biological activity of 28:109 (+)-Tetrandine bisbenzylisoquinoline) 29:578 effects on ACE 29:578 (+)-Tetrandine-2'-N-c~-oxide (bisbenzylisoquinoline) 29:578 effects on ACE 29:578 Tetraneurin A 29:91 activity in TPA assay system 29:91 Tetranichus mites 28:433 neem extracts against 28:433 1,2,3,6-Tetra- O-galloyl-[3- D-glucose (galloyl ester) 29:589 effects on PEP 29:589
N:,N s,N 1~N 14-Tetra-p- c oumaro ylspermidine (phenolic amide) 29:574 effects on HIV-1 protease 29:574 Tetratogenic activity 23:569 ofveratrum alkaloids 23:569 Tetratogenicity 27:309 Tetrazomine 10:117,19:289-290 antibacterial activity of 10:117 antitumor activity of 10:117; 19:290 antimicrobial activity of 19:290 cytotoxicity of 19:290 TG-1 2:445,446 anti-fungal activity of 2:445,446 TG-11 2:446 anti-fungal activity of 2:446 Th2 cells 30:773 differentiation of 30:773 in antibody production 30:773 in humoral immunity 30:773 Th2-type immune response 30:778 inhibition by IFNy 30:778 Thalamocortical connection 30:377 development of 30:377 Thalamus 30:193,377 serotonin synthesis in 30:377 (+)-Thalicarpine 30:567,595 as platelet aggregation inhibitor 30:594 Thalifoline 30:566,590 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:589 Theaflavin digallate (polycyclic benzopyran) 29:583 effects on type IV collagenase 29:583 Theonellamides 26:1185 cytotoxicity of 26:1185 Theonellapeptolides 26:1189 antimicrobial activity of 26:1189 Theonezolides 28:710 as cytotoxic agents 28:710 Therapeutic agents 30:396 for AIDS 30:396
1213
Therapeutic application 30:399 of sulphated polysaccharide (PS) 30:399 Therapeutic effects 27:379 of aroma 27:379 Therapeutic efficacy 21:697 against HSV-1 corneal infection 21:697 of SDB 21:697 Therapeutic potential 27:893 of flavonoids 27:893 Therapeutic uses 22:736 oftropane alkaloids 22:736 Therapeutic vaccines 28:541 against cancer 28:541 Therapy 30:393 for bacterial infection 30:393 for fungal infection 30:393 for parasitic infection 30:393 for viral infection 30:393 Thermal model ofnociception 30:205 analgesic effect in 30:205 Thienamycin 4:431,432;12:145 antibacterial activity of 4:431, 432;12:145 antibiotic activity of 12:122 [3-1actamase inhibition by 12:145 (+)-Thienamycin synthesis of 13:498-504 Thiocarbapyranoses 29:488 as neuraminidase inhibitor 29:488 in medicinal chemistry 29:488 Thiophenes 24:521,522 as antiviral compound 24:521, 522 2-Thioxopyrrolidines 26:1098 antifungal activity of 26:1098 Threonine 27:850 activitiy of 27:850 Thrombin 30:70,594,838 platelet aggregation induction 30:by 594 role in blood coagulation 30:70 role in platelet activation 30:70 role in pulmonary vascular injury 30:70
Thrombin fibrin clots 30:154 generation of 30:154 Thrombin receptor agonist peptide 30:69,70 in cultured HUVECs 30:69 Thrombin time assay 30:403 Thrombin-induced adhesion 30:55 Thrombin-stimulated ELAM- 1 30:70,71 inhibitory effect on 70,71 Thrombocystosis 30:839 treatment of 30:839 Thrombolytic agent 30:839 adverse effect of 30:839 bleeding complications due to 30:839 recombinant prourokinase (proUK) as 30:839 recombinant tissue-type plasminogen activator as 30:839 re-occlusion due to 30:839 staphylokinase as 30:839 Thromboplastin time assay 30:403 Thrombosis 30:55,839,840 role of natural products in 30:55 treatment of 30:839,840 Thromboxane B2 (TXBc~) 22:112 Thromboxane synthase inhibitor 25:593 THS hepatocyte apoptosis effect 25:467 THS inhibited hepatocyte apoptosis 25:468 c~-Thujaplicin (2-isopropyltropolone) (tropolone monoterpene) 29:583 effects on carboxypeptidase A 29:583 [3-Thujone 28:427 acaricidal activity of 28:427 Thymelaceousplants 27:833 activator from 27:833 Thymol 28:426 as bioactive monoterpenoid 28:426 Thyroid hormone 27:314 Thyroxine 27:314 [Tic 2] dermorphin 30:809 activity in functional bioassay 30:809
1214 [Tic 2, Leu 5] enkephalin 30:809 activity in functional bioassay 30:809 [Tic 2] deltorphin C 30:807,818 activity in MVD bioassay 30:807,818 agonist activity in vitro 30:818 Timosaponin 24:919-922 anti-hyperglycemic effects of 24:919-922 potentiation of pilocarpineinduced saliva secretion by 24:921 Tirandamycin A 28:131 biological activity of 28:131 Tirotundin 29:89 activity in NFkB assay system 29:89 AT-Tirucallol (tirucalla-7,24-dien-313ol) (triterpene) 29:588 effects on CHY 29:588 Tissue bioassays 29:29 Drosophila melanogaster use in 29:31 ecdysone activity in 29:31 20-hydroxyecdysone activity in 29:31 imaginal disc bioassay as 29:29 inokosterone activity in 29:31 makisterone A activity in 29:31 ponasterone A activity in 29:31 rubrosterone tested in 29:31 use of Calliphora victina in 29:31 use of Chilo suppressalis in 29:29 Tissue plasminogen activator (t-PA) 30:830,844 Tithofolinolide 29:87 activity in DIF assay system 29:87 TLR2 30:777,778,781,782 from gram-positive bacteria 30:778 in ARS-2 mediated cellular activation 30:781 in cellular reponses 30:782 T-Lymphocytes 22:259;27:799
TMB (3,4,5,-trimethoxybenzoy) 25:477 cytotoxic action of 25:477 TNF-t~ 25:461,462-465,469,472, 474;28:320 caspase activity of 28:320 dependent liver injury 25:470 in macrophages treatment 25:473 oncolytic effects 25:460 inhibition by THS 25:468 TNF-a bioassay system 29:103 acanthoic acid activity in 29:103 2c~-acetoxy- 14-hydroxy- 15-isovaleroy-loxy-9-oxo-costunolide activity in 29:89 TNF-c~ cytotoxicity 25:475,477 TNF-c~ dependent liver injury 25:472, 473,476,477 TNF-c~ induced lethality 25:474 TNF-a production 25:468,470,471473,475 suppression of 25:472 inhibition of 25:475 TNF-c~ receptor (TNF-R) 25:477 TNF-a release 28:220 Artocarpus flavonoids against 28:220 TNF-c~-dependent inflammatory liver injury 25:460,461,465,466 TNF-c~-dependent models 25:476 TNF-~-gene expression 25:470 TNF-c~-induced hepatocyte apoptosis 25:471 TNF-c~-induced hepatotoxicity 25:469,471 TNF-c~-mediated cytotoxicity 25:466 TNF-c~-sensitive L929 cells 25:467 Tobacco hornworm 24:865 bioassay of 24:865 Tobacco mosaic virus infection 30:412 against yeast mannans 30:412 Toga virus infection 30:409 in pregnant women 30:409 vaccination against 30:409 Toga viruses 30:394,409 Tolerance 30:194,799 due to analgesic alkaloid 30:799 due to opioids 30:194
1215 Tolypodiol 29:100 activity in TPA assay system 29:100 Tomatidine 25:295,296,297,300, 301,306,316-318 detoxification of 25:293 enzymatic detoxification of 25:304 mechanism of action of 25:306 Tomatine-detoxyfying enzymes 25:293 Tonic 30:64 carp as 30:64 Tonic agent 23:642 of Teucrium sp.as 23:642 Tonsillitis 30:88 use of Platycodon grandiflorum in 30:88 Toothache 30:203 use of ginseng root in 30:203 TOP-53 26:163 in anticancer treatment 26:163 Topoisomerase (TOPO) II-mediated decateration of kinetoplast DNA 25:820 Topoisomerase 1-inhibitory properties 27:851 from Tabebuia avellanadae tree 27:851 Topoisomerase I 25:721 Topoisomerase I inhibitor 26:825 Topoisomerase II 25:708,709,862 Topoisomerase II expression 26:924 Topoisomerase II-sensitive (CHO) cell line Xrs-6 25:824 Topoisomerase inhibitory 24:867,868 bioassay of 24:867-868 Topoisomerase inhibitory activity 24:848 of costunolide 24:848 Topozolin 28:229 biological activity of 28:229 Topsentia sp. 28:701 in guanosine diphosphate/Gprotein RAS exchange assay 28:701 Tormentic acid (triterpene) 29:575; 30:207
antinocicieptive effect of 30:207 effects on HIV-1 protease 29:575 Total plasma cholesterol 30:95 effect of chitin-chitosan on 30:95 Totarol 29:103 activity in EBV bioassay system 29:103 Totipotency 7:94-96 of cell cultures 7:94-96 Toxadocial A 28:711 thrombin inhibition by 28:711 Toxadocial B 28:711 thrombin inhibition by 28:711 Toxadocial C 28:711 thrombin inhibition by 28:711 Toxic chemical 30:762 dioxin as 30:762 polychlorinated biphenyl (PCB) as 30:762 Toxic xenobiotic 25:935 Toxicity 7:279-282;24:153 of asterosaponins 7:303 of fumonisine 13:532 of holothurins 7:279-282 of quassinoids 7:388,389 to reproductive organs 27:311 Toxicity assays 26:790 for extracellular promastigote 26:790 Toxicity effects 27:444 on animals 27:444 Toxicity study 27:306 of stevioside 27:306 Toxicological activities 21:4 Toxicological responses 21:99 Toxicological studies 27:301 Toxiferine 25:528 as immunosuppressive drug 25:528 Toxigenic moulds 9:201-203 Toxin 5:403,404,411 ;9:9-11,209-211 of echinoderms 7:265-316 T-2 Toxin 9:28,210 T-2 Toxin analogues 6:242 Toyocamycin 24:547,548 antiviral microbial-derived compound 24:547,548
1216
TPA 25:55,59 inhibitory effects on 25:55 induction of EBV-EA activation by 25:59 TPA induced edema (TPA) 25:45 TPA induced inhibition 25:45 role of omithine decarboxylase (ODC) 25:45,66 TPA induced ornithine decarboxylase inhibition (ODC) 25:45,46 TPA induced skin tumors 25:46 TPA stimulated 32pi incorporation 25:60 in HeLa cells 25:60 TPA-induced assay 25:58,61 TPA-induced ear edema 25:57,58 TPA-induced edema inhibition (CRO) 25:45 TPA-induced inflammation 25:47,48,63 TPA-induced inflammatory edema 25:56 TPA-induced ODC accumulation 25:60 TPA-mediated DNA 25:937 TPA-type tumor promoters 25:61 Trachelogenin 24:742 inhibition of replication of HIV- 1 24:742 Trachyloban- 19-oic acid 29:103 activity in EBV bioassay system 29:103 trans-Communic acid methyl ester activity in EBV bioassay system 29:101 Tragacanthin polysaccharide (PS) 30:411 effect on liver 30:411 effect on liver infection scores 30:411 effect on mortality 30:411 effect on serum transaminase 30:411 effect on spleen virus titer 30:411 from Astragalus brachycentrus 30:411 Tranquillizers 21:101 Tranquillizing activity 30:200 of droperidol 30:200
Transcriptional activity 30:496,497 of 1c~,25(OH)2D analogue 30:497 Transcriptional factor 25:470 Transcriptional inhibitors 25:461 Translation inhibitors 21:98 Transplantable Meth A tumor 30:776 Transplanted murine tumor cell lines P 388 30:27 pironetin against 30:27 TRAP-induced ELAM- 1 expression 30:70 inhibition of 30:70 Treatment 26:787-788,804;30:597 of Chagas disease 26:787 of cryptosporidiosis 26:788 of malaria 26:804;30:597 of postpartum hemorrhage 30:597 ofmoming sickness 30:597 Tremorgenic toxins 24:1060 Trichilia glabra 30:411 anti-polio virus activity of 30:411 Trichommonas foetus 2:293 staurosporine against 12:397 Trichothecene complex 30:751 of antibiotics 30:751 Trichothecenes 30:751 fungal toxins 30:751 phytotoxicity of 30:751 role in mycotoxicoses 30:751 role in plant pathogenicity 30:751 toxicity toward eucaryotic organisms 30:751 Trichothecinol A 29:88 activity in EBV assay system 29:88 Trichothecinols B 29:88 activity in EBV assay system 29:88 Trifluridine 24:487 as anti-viral agent 24:487 ent-3[3,16(x,17-Trihydroxyatisane 29:100 activity in mam-2 assay system 29:100
1217 cis-3,5,4'-Trihydroxystilbene 4'-O-[~-
D-(6-O-galloyl)- glucoside (stilbene glycoside) 29:589 effects on PEP 29:589 Trillium glycosides 2:443 antifungal activity of 2:443 1,2,6-Tri-O-galloylglucose (glucose gallic acid ester) 29:589 effects on PEP 29:589 N 1, N 5, N: ~ ri-p-coumaro ylspermi dine (phenolic amide) 29:574 effects on HIV- 1 protease 29:574 Triphenyl phenol scutigeral 30:193 analgesic action of 30:193 Tripterygium wilfordii 30:639,641,648, 664,676,689,690 as anti-AIDS agent 30:639 as anticancer 30:639 as insecticide 30:639 as traditional medicine 30:689 celastrol from 30:664 for rheumatoid arthritis treatment 30:689 for spondylitis treatment 30:689 in treatment of rheumatoid arthritis 30:639 in treatment of spondylitis 30:639 inhibitory effects of 30:690 Triptofordin F-2 29:88 activity in EBV assay system 29:88 Triptogelin A-1 29:88 activity in EBV assay system 29:88 activity in skin-1 assay system 29:88 Triptolide 29:100,198 activity in APO assay system 29:100 activity in COX assay system 29:100 activity in NFkB assay system 29:100 activity in TNFc~ assay system 29:100 against murine L- 1210 leukemia
29:200 biological activity of 29:198 cytotoxicity of 29:200 immunosuppressive activity of 29:200 inflammatory properties of 29:200 Triptoquinone A 29:99 activity in iNOS assay system 29:99 Triterpene glycoside 28:596,587,589 antifungal activity of 28:589 cytotoxic activity of 28:589 cytostatic activity of 28:589 hemolytic activity of 28:589 immunomodulatory activity of 28:589 Triterpenes 30:637-663 biological activities of 30:637 physiological function of 30:637 chemistry of 30:637-663 Triterpenoid fractions 30:59,60,62 activity in matrigel-implanted angiogenesis assay 30:62 effects on hemoglobin 30:59,60 effects on leukocytes 30:59,60 effects on red cell 30:59,60 isolation of 30:62 Triterpenoids 25:43;30:55,56,58,59, 61,64 antiinflammatory activity of 25:43 antimetastatic effects of 30:58 antitumor activity of 25:43;30:58 effect on angiogenesis 30:61 effect on DNA synthesis 30:61 effect on liver metastasis 30:55 effect on primary solid-tumor growth 30:64 effect on secondary metastatic tumor growth 30:64 effect on tumor cell colonies 30:59 effect on tumor growth 30:55 Triticum aestivum L. 27:215 allelopathic interaction of 27:214-218
1218
Tropical diseases 30:329 malaria as 30:329 TRPM8 30:193 type of ionotropic receptor 30:193 use in cold-allodynia 30:193 TRPVI 30:193 activation of 30:193 receptor desensitisation of 30:193 role in neuropeptide release 30:193 role in nociceptor excitation 30:193 TRPVI (VRI) activation 30:193 by acidosis 30:193 by lipid mediators 30:193 by noxious heat 30:193 TRPVI expression 30:206 effect of capsaicin on 30:206 effect ofpolygodial on 30:206 TRPVI receptor blockade 30:203 by ginsenosides 30:203 Trypanocidal activity 26:800 Trypanocidal effect 30:741 of Paraguayan compositae 30:741 Trypanosomal 24:799 biological activity 24:799 Trypanosomiasis 26:781,785,786,787, 840 Trypanosomicidal activity 26:230 of veraguensin 26:230 of grandisin 26:230 Trypsin production 30:204 inhibition by hederagenin monodesmosides 30:204 Tryptase inhibitor 26:1129 Tryptophan decarboxylase activity 30:371 in brain neurons 30:371 in non-nervous tissue cells 30:371 Tryptophan hydroxylase (TPH) activity 30:370 in beta-cells 30:370 in intestinal cells 30:370 in mast cells 30:370 in mononuclear leukocytes
30:370 in pancreatic enterochromaffin cells 30:370 Tubeimoside 1 21:634,637,639,641, 657,731 antitumor activity of 21:733 Tuberculosis 12:37 rifampicin for 12:37 Tuberous sclerosis 30:374 autistic features in 30:374 Tumor 28:532;30:61 effect of lipid A on 28:532 in host response to LPS 28:531 in LLC-bearing mice 30:61 Tumor cell colonies 30:59 role of triterpenoid fractions 30:59 Tumor growth 28:581 ;30:56,57,60, 64,70 effects of 2,3,5,4 '-tetrahydroxystilbene-2-O-D-glucoside on 28:581 efect of fucoidan on 30:56 effect of triterpenoid fractions on 30:60 in LLC-bearing mice 28:581 in sarcoma 30:56 in spleen 30:64 inhibition by carp oil 30:64 inhibition by oleic acid 30:64 prevention of 30:60 Tumor metastasis 25:440,454;30:55 role of natural products in 30:55 Tumor necrosis factor-or (TNF-ct) 5:385,387 ;12:396;23:142,475; 25:459,460,461,477,598;27:851; 28:219 as tumor promoter 28:219 staurosporine effect on 12:396 Tumor prevention 30:64 use of carp oil 30:64 Tumor production inhibition 30:695 Tumor promoter 30:592 TPA as 30:592 Tumor promoters 2:286,287 Tumor specificity 25:442 Tumor therapy 6:261 polyene macrolides in 6:261
1219 Tumorigenesis 30:316 initiation of 30:316 promotion of 30:316 Tumor-inhibitory activity 23:126; 24:202-206 of yeast glucan 23:126 Tumor-promoting 12:233-274 diterpenes 12:233-274 synthesis of 12:233-274 phorbol ester 25:190 Tumor-promotion agents 30:592 diterpene esters from 30:592 12-O-tetradecanoylphorbol 13acetate (TPA) as 30:592 Tumour-inhibiting activity 17:341; 20:408 Tumour-promoter activity 15:462 of pendolmycin 15:462 Tuna oil 28:566 anti-tumor activity of 28:566 Two-stage mouse skin model 30:591 cancer chemopreventive activity in 30:591 Tyr-(Me)z-D-Phe-Gly-Val-Val-NH2 30:812,813 activity in GPI assay 30:812 binding bioactivity of 30:813 functional bioactivity of 30:813 Tyr-(Me)z-D-Phe-NH2 30:812,813 activity in GPI assay 30:812 binding bioactivity of 30:813 functional bioactivity of 30:813 [Tyr(Me)z-Phe] peptides 30:813 binding bioactivity of 30:813 functional bioactivity of 30:813 Tyr(Me)2-Phe-NH2 30:813 binding bioactivity of 30:813 functional bioactivity of 30:813 Tyr-(Me)z-Phe-NHCH3 30:812 energy map of 30:812 Tyr-D-Ala-Phe- [[3-D-Glc(OAc )4]TyrPro-Ser-NH2 30:815 receptor binding properties of 30:815 Tyr-D-Ala-Phe-Asp-Val-Val-Gly-NH2 (deltorphin C) 30:815 receptor binding properties of 30:815
Tyr-D-Ala-Phe-Asp-Val-Val-Thr([3-DG lc)-G ly-NH 2Tyr-D-Ala-P he-Thr[ [3D-Glc(OAc)4]-Val-Val-Gly-NH2 30:815 receptor binding properties of 30:815 Tyr-D-Ala-Phe-Asp-Val-Val-Thr[ [3-DGlc(OAc)4]-Gly-NH2 30:815 receptor binding properties of 30:815 Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2 (deltorphin C) 30:815 receptor binding properties of 30:815 Tyr-D-Ala-Phe-Gly-Tyr-Pro-Thr([3-DGlc)-Gly-NH2 30:815 receptor binding properties of 30:815 Tyr-D-Ala- Phe-G ly-Tyr-Pro-Thr [[3-DGlc(OAc)4]-Gly-NH2 30:815 receptor binding properties of 30:815 Tyr-D-Ala-Phe-Thr([3-D-Glc)-Tyr-ProSer-NH2 30:815 receptor binding properties of 30:815 Tyr-D-Ala-P he-Thr([3-D-G lc )-V a 1-ValGly-NH2 30:815 receptor binding properties of 30:815 Tyrosinase activity assay 21:587 Tyrosinase inhibitory activity 21:587 Tyrosine kinase 12:394 Tyrosine kinase activity 15:441;21:135; 27:854 Tyrosine kinase inhibition 21:135,152 Tyrosine kinase inhibitors 15:447-449 biological activity of 15:447-449 Tyrosine kinase inhibitors 25:691,720 Tyrosine kinase-mediated signaling 25:545 Tyrosine kinases receptor 27:824, 825,827 Tyrosine-specific kinase 19:178 inhibitor of 19:178 Tyr-Tic-NH2 30:809 activity in functional bioassay 30:809
1220
Tyr-Tic-Phe-NH2 30:806 as 5 selective antagonist 30:806 U2 66 myeloma cell 25:273 UCN-01-UCN-02 12:386 antitumor activity of 12:395 protein kinase inhibitor of 12:386 Udoteatrial 16:312-316 antimicrobial activity of 16:312, 315-316 Ulapualides A 19:609 antifungal activity of 19:609 Ulicyclamide 5:419,420;10:242 cytotoxic activity of 5:419 Ulithiacyclamide 5:419;10:242 cytotoxic activity 4:101,102; 5:419 Unipolar depression 30:369 effect of circadian activity on 30:369 Unsaturated carbapyranoses 29:475 as enzyme inhibitors 29:475 as herbicidal 29:475 biological properties of 29:475 Unsaturated ketonucleosides 4:253 tumor inhibition by 4:253 U-plasminogen activator (u-PA) 30:844 Urdamycin A 11:134 antifungal activity of 11:134 antitumor activity of 11:134 Ureterolithiasis-drug-therapy 27:382 Urinary tract infections 26:50 Herniaria hirsuta in 26:50 Urine retention 30:194 as opioid's side effect 30:194 Uroterpenol 29:83 activity in mam-2 assay system 29:83 activity in RAS assay system 29:83 Ursane triterpene 29:585 effect on CHY 29:585 Ursolic acid 28:18,40;29:588 effects on HIV- 1 protease 29:575 effects on LELA 29:588 inhibition of HIV- 1 protease
dimerization by 28:18 Ursolic acid methyl ester (ursene triterpene) 29:575 effects on HIV- 1 protease 29:575 Usambarensine 26:1062 anticancer activity of 26:1060 Uterine tumor 30:27 effect of pironetin derivatives in 30:27 Uusambarine 26:1062 anticancer activity of 26:1060 Uvaol (triterpene) 29:588 effects on LELA 29:588 Uvaol (Urs- 12-ene-3,28-diol) (ursene triterpene) 29:575 effects on HIV-1 protease 29:575
Vaccaria segetalis 26:50 imunomodulatory effect of 50 Vaccination 30:408 for respiratory infection 30:408 Valepotriates 13:660 from Valeriana officinalis 13:660 Validamine 29:481 effects on galactosidases 29:481 effects on mannosidases 29:481 effects on N-linked oligosaccharide-process ing mannosidases 29:481 Validamycin 7:47 as a-glucosidase inhibitors 7:47 Valienamine 13:189,195,198;29:486 as neuraminidase inhibitors 29:487 as c~-amylase inhibitor 29:486 c~-glucosidase inhibitors of 7:46;10:518 yeast a-glucosidase inhibitor of 10:518 Valinuoctins 24:459 FPTase inhibition by 24:459 Valiolamine 13:189,195 yeast c~-glucosidase inhibitor of 10:518
1221
Valiolamines 29:484 as glucosidase inhibitor 29:484 biological potential of 29:484 in clinical trials 29:484 in treatment of diabetes 29:484 Valproic acid 22:507 Vancomycin 25:791 Vancoresmycin 28:150 activity against gram-positive bacteria 28:150 Vanilloid receptor agonist 30:202 olvanil as 30:202 capsaicin as 30:202 structure of 30:202 Vanilloid receptor antagonist 30:201, 202 capsazepine as 30:201,202 Varicella-Zoster virus 30:394 cause of 30:394 Varroajacobsoni 28:387 toxicity of 28:387 Varroa mites 28:383,384,392 biological activity of 28:392 Vascular physiological action 30:55,69 of natural products 30:55,69 Vasoconstriction 21:91 Vasodilating activity 21:379 Vasodilator 23:358 scoparone as 23:358 Vasodilator effect 25:595 of acetylcholine 25:595 Vasodilatory activity 30:275 ofSatujera obovata 30:275 Vasopressin 27:800 Vasoprotective agent 22:443 Vasoprotective effects 28:302 of green tea 28:302 Vasorelaxant chalcone 25:540 (+)-Vateamine-2' [3-N-oxide 30:567, 590,595 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 as platelet aggregation inhibitor 30:594 cytotoxic effect of 30:589 Veinotonic activities 21:633
Veraguensin 26:230 trypanosomicidal activity of 26:230 Verapamil 25:534,673 as CaZ+-channel blocker 25:487 Vermisporin 28:125 antimicrobial activity of 28:125 Vernonia amygdalina 28:400 tick toxicity of 28:400 Verrucarins 30:743 arenavirus junin 30:743 herpes simplex virus type II (HSV-2) 30:743 Verrucosin 26:228 ofantiviral activity 26:228 Vertebrate toxicity 21:98 Vesicant activity 1:365 Vesicular glutamate transporters 25:538 Vesicular monoamine transporter type 2 (VMAT2) inhibitor 30:380 Vesicular monoamine transporters 25:538 Vesicular stomatitis virus (VSV) 30:743,752 replication of 30:743 Vesititol 28:224 anti-microbial activity of 28:224 Vestitol 28:243 anti-Helicobacter pylori activity of 28:243 Veterinary medicine 28:383 for ectoparasites control 28:383 Vetiver grass 28:399 for controlling ticks 28:399 Viagra (sildenafil) 25:541 Vicolides 29:89 activity in CTN bioassay system 29:89 Vinblastine 2:370,372,287,389,390; 4:29;8:283;12:179;13:633;14:805884 ;19:748 ;20:458;25:269 anticancer activity of 14:805 Vincristine 2:390,398;9:387;11:5, 12:396;13:633 ;20:458 anticancer activity of 14:805 Viral diseases 30:732 Viral DNA 30:226 integration of 30:226
1222 Viral DNA polymers 30:395 for herpes simplex virus 30:395 for varicella-zoster virus 30:395 phosphorylation of 30:395 Viral envelope glycoproteins 30:404 natural sulphated polysaccharide (PS) 30:404 Viral infections 30:394,742 therapy of 30:394 Viral mutation 30:407 Viral proteins 24:477,478 Virantmycin 29:339 antifungal activity of 29:339 antiviral activity of 29:339 effects on lipids peroxidation 29:339 inhibition of glutamate toxicity 29:339 Virenamide A 28:644 as cytotoxic linear peptides 28:644 Virenamide B 28:644 as cytotoxic linear peptides 28:644 Virenamide C 28:644 as cytotoxic linear peptides 28:644 Viridin antibiotics 21:238 Viroid-like RNA 30:406 Virucidal activity 21:665 Virucidal agents 30:627 hypericin as 30:627 pseudohypericin as 30:627 Virus 30:393,394 adeno- 30:393 herpes- 30:393 pox- 30:393 replication of 30:394 Virus replication 30:395 role of 30:395 Virus-cell binding inhibitors 30:398 inhibition of 30:398 Virus-specific treatment 30:407 Vismione D 7:419 antimalarial activity of 7:424 antiproliferative activity of 7:419 Vitamin AI 30:520 dietary source of 30:520 for development 30:520
role in visual process 30:520 structure of 30:520 Vitamin C 23:739 Vitamin D 30:498 adverse effect of 30:498 Vitamin D analogues 30:483,484, 485,489 in vivo activities of 30:484 metabolism of 30:485 pharmacokinetic properties of 30:484 structure-activity relationships (SARs) of 30:483 Vitamin D response elements (VDREs) 30:496 promoter of 30:496 Vitamin D2 30:484,490 role in bone calcium mobilization 30:484 role in intestinal calcium transport 30:484 role in rickets 30:484 Vitamin deficient rat serum DBP 30:496 competitive binding to 30:496 Vitamin Kt (naphthoquinone) 29:585 effects on coagulation 29:585 Vitamin P 23:740 Vma• values 30:95 oflipase activity 30:95 Vminalol 29:585 effect on CHY 29:585 effects on HIV- 1 protease 29:574 effects on collagenase 29:583 Voltage-gated Ca 2+channels 25:517 Voltage-gated ion channels 25:520 Voltage-gated K + channel 25:531 Voltage-gated Na + channels 25:533 Voltage-sensitive calcium channel 30:203 blockade of 30:203 by ginsenosides 30:203 VSV 24:524 activity of actinoplanic acids against 24:524
1223
Warbruganal 29:87 activity in skin-1 assay system 29:87 (-)-Warburganal 14:413-421 antifeedant properties 14:413-421 Warts 30:405 Weight loss 30:56 due to cancer drugs chemotherapy 30:56 Weolignans 27:765 biological activity of 27:765 Wheat cystatins 29:594 effects on cathepsin B 29:594 effects on cathepsins 29:594 effects on chymopapain 29:594 effects on cysteine proteases 29:594 effects on ficin 29:594 effects on papain 29:594 Whole insect assays 29:29 20E 22-O-benzoate tested in 29:30 cyasterone activity in 29:30 24(28)-dehydromakisterone A activity in 29:30 2-deoxy-20-hydroxyecdysone activity in 29:30 20E 2,25-dibenzoate tested in 29:30 ecdysones tested in 29:30 integristerone A activity in 29:30 nusilsterone activity in 29:30 polypodine B activity in 29:30 ponasterone A activity in 29:30 rapisterone D activity in 29:30 turkesterone activity in 29:30 Wieland Miescher ketone 24:175-213 bioactive terpenes from 24:175-213 Wighteone 28:226 anti-human immunodeficiency virus (HIV) activity of 28:226 Wighteone 28:229 biological activity of 28:229
Wikstroemia indica 27:833 activator from 27:833 Willow (Salix species) 30:192 analgesic properties of 30:192 anti-inflammatory properties of 30:192 antipyretic properties of 192 Withanolide 19:463,470 antitumor activity of 19:470 biological activities of 19:470 insect antifeedant properties of 19:470 Wogonin 30:287 anti-inflammatory action of 30:289 structure of 30:287 Wounding-Induced Protein Kinase 26:946 Writhing test 30:207 activity of 13-narin-II8-4'-Omeeridictoyol in 30:207 role ofbiflavonoid in 30:207 X14766A 29:317 against gram-positive bacteria 29:315 Xanthoangelol B 30:74,77 inhibitory mechanism of 30:74,77 effect on phenylephrine-induced vasoconstriction 30:74 Xanthoangelol E 30:76 effect on phenylephrine-induced vasoconstriction 30:74,76 inhibitory action of 30:76 Xanthobaccin A 28:140 as fungitoxic metabolite 28:140 Xanthobaccin B 28:140 as fungitoxic metabolite 28:140 Xanthobaccin C 28:140 as fungitoxic metabolite 28:140 Xanthone a-mangostin 25:531,536 inhibitor of Ca2+-ATPase 25:536 Xanthones 24:503-509 as antiviral compound 24:503509 Xenobiotics 9:582,583;26:755 and cooxidation 9:582,583
1224
Xenochemicals 18:680;18:680,681 Xenocoumacins 15:381-472 biological activities of 15:408412 Xestocylamine activity 24:573 inhibition of protein kinase C 24:573 Xestoquinolide B 28:677 protein kinase activity of 28:677 Xylanasic 24:983-993 enzymatic activity 24:983-993 Yangambin 24:741 anti-platelet aggregation activity of 24:741 (+)-Yangambin 26:242 as PAF-induced inhibitor 26:242 (-)-Yatein 26:213;30:569,587,588, 590,595 activity against A549 (human lung adenocarcinoma) 30:588 activity against HT-29 (human colon carcinoma) 30:588 activity against KB-16 (human oral epidermal carcinoma) 30:588 activity against P-388 (murine lymphocytic leukemia) 30:588 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 as platelet aggregation inhibitor 30:594 cytotoxic effect of 26:213; 30:589 Yessotoxin 28:653 in diarrhetic shellfish poisoning (DSP) 28:653 Yohimbine 25:530 as immunosuppressive drug 25:530 Yomogin 87 activity in iNOS assay system 29:87 activity in NO assay system 29:87
Zahavin A 29:103 activity in AOS bioassay system 29:103 Zalcitabin 24:474,486,488 as anti-viral agent 24:474,486, 488 Zea mays 27:215 allelopathic interaction of 27:215 Zerumbone 29:91 activity in EBV assay system 29:91 activity in colon-1 assay system 29:91 activity in AOS assay system 29:91 activity in APO assay system 29:91 activity in COX assay system 29:91 activity in iNOS assay system 29:91 activity in TNFot assay system 29:91 Zidovudine 24:474,486,487 as anti-viral agent 24:474,486, 487 Zooecdysteroids 29:10 biochemical roles of 29:10 Zoospore attractants 22:482-502 Zymogen activation 25:391 Zymosan 30:778 from yeast 30:778 Zymosan-activated macrophages 25:274
1225
C U M U L A T I V E B I O L O G I C A L S O U R C E INDEX VOLUMES 1-30 Aaronsohnia sp. 29:683 Abernaemontana penduliflora 28:234 Abies amabnilis 22:391 Abies balsamea 22:384 from balsam 22:384 Abies grandis 22:391 Abies koreana 20:619 Abies mariestii 20:619 Abies marocana 29:99 Abrus sp. 25:180 Abrus contaniensis 25:93 Abrus fruticulosus 15:26;27:15 abrusoside A from 27:15 abrusoside B from 27:15 abrusoside C from 27:15 abrusoside D from 27:15 Abrus precatorius 7:152,15:25; 21:674 ;22:510;25:93 ;27:15,27 abrusoside A from 27:15,27 abrusoside B from 27:15,27 abrusoside C from 27:15,27 abrusoside D from 27:15,27 abrusoside E from 27:15,27 for epilepsy 22:510 cycloartane from 21:674 Absidia sp. 25:160 Acacia astringens 7:427 Acacia auriculiformis 21:674; 23:487,498;26:467 triterpenoid saponin from 21:674 Acacia catechu 29:678,680 Acacia confusa 29:603 Acacia melanoxylon 27:838 Acacia nilotica 7:427;26:358 Acacia spp. 29:582 Acacia tomentosa 7:427 Acalycigorigia inermis 5:370 Acalycigorigia sp. 5:368,369 Acalypha fruticosa Forsk. 22:510 for epilepsy 22:510 Acanthaster planci 7:288 acanthaglycosides A-D,F from 7:288 marthasteroside A from 7:288 thornasteroside A from 7:288
Acanthella klethra 25:848,852 Acanthella pulcherrima 25:852 Acanthella sp. 21:334;25:852,853;28:663 kalihinol G of 28:663 kalihinol H of 28:663 Acanthella acuta 21:329;25:848,852,853 Acanthella aurantica 21:270 Acanthella cavernosa 21:351,353,355, 356,359,361,365-367;25:689,858; 26:465;28:663 lO-epi-isokalihinol H from 28:663 15-isothiocyanato- 1-epi-kalihinene from 28:663 Acanthella klethra 20:525;26:810;28:662 isothiocyanates from 28:662 Acanthella pukherrina 25:853;28:660 isothiocyanates from 28:660 sesquiterpenes from 28:660 Acanthodendrilla sp. 25:704;28:702 acanthosterol sulfate A of 28:702 acanthosterol sulfate B of 28:702 acanthosterol sulfate C of 28:702 acanthosterol sulfate D of 28:702 acanthosterol sulfate F of 28:702 acanthosterol sulfate G of 28:702 acanthosterol sulfate H of 28:702 acanthosterol sulfate I of 28:702 acanthosterol sulfate J of 28:702 antifungal activity of 28:702 Acanthodris nanaimoensis 19:139 Acantholippia seriphioides 21:618 Acanthomyops claviger 6:454 Acanthopanax koreanum 29:103 Acanthophyllum gypsophiloides 26:3 Acanthophyllum squarrosum 24:149; 26:31,50,55 squarroside A from 26:31 Acanthoscelides obtectus 10:160 Acanthus ebracteatus 7:176 Acanthus illicifolius 7:176,179,181,182, 189-191,193 Acanthus mollis 27:188,191 Acarapis woodi 28:387,390 in honey bees' tracheal tubes
1226 28:387 infestations in Minnesota 28:390 Acaria saxatilis 22:634 Acarnus bergquistae 25:724 Acarus siro 28:382 as mite sp. 28:382 Acarus siro 28:423 Acanthus mollis 27:191 Acer nikoense 26:889,895,899 Acer sp. 21:502;26:905 Acer saccharumn 25:666 Acetobacter suboxydans 17:636-637 Achantaster planci 15:45 Acheta domesticus 22:387;29:6 Achilla arten 21:378 Achillea sp. 24:684,687;29:683 Achillea arten 21:378 tetradecadienoylpyrrolidine from 21:378 Achillea millefolium 10:151;21:378; 24:686,688,689,690 Achillea nana 10:151;21:378 Achillea nobelikii 24:687-689 Achillea pannonica 29:88 Achillea ptormica 24:691 Achillea setacea 29:89 Achillea sudetica 24:687 Achyranthes aspera L. 22:510 for hysteria 22:510 Achyranthes fauriei 29:10 Achyrocline flaccida 22:347 7,4-dihydroxy-5-methoxy flavone from 22:347 Achyrocline satureioides 22:346 as antispasmodic 22:346 as choleretic 22:346 as hepatoprotective 22:346 quercetin from 22:346 Aciculites orientalis 26:1214 Aciculites sp. 26:1175 Acilius sulcatus 5:700 Acinetobacter calcoaceticus 12:103; 27:218 Acinos suaveolens 30:276 apigenin from 30:276 Acnistus arborescens 20:247 Acnistus breviflorus 20:234 Acomycota 22:246 basidiomycetes from 22:246
Aconitum 26:868 Aconitumjaponicum. 22:510 for convulsions 22:510 Aconitum napellus 20:19 Acorospora gobiensis 25:802 Acorus calamus 21:595;22:510;28:401 in hysteria, convulsions and epilepsy 22:510 Acorus caninum 26:471 Acorus graminous 26:362,470 Acosmium panamense 27:269 Acrasiomycetes 9:220 Acremonium sp. 27:805 Acronychia baueri 13:347,349;20:789 Acronychia oigophylebeia 13:348,350 oligophylidine from 13:348,350 Acroscyphus sphaerophoides 5:310 Acrostalagmus genus 21:221 ;28:454 Acrostalamus fungi 28:455 acrostalidic acid from 28:455 acrostalic acid from 28:455 isoacrostalidic acid from 28:455 Actaea 25:180 Actinidia deliciosa 26:1145,1158 Actinidia polygama Miq. 16:290,291 Actinobacter calcoaceticus 30:421 Actinodaphne lancifolia 28:419 Actinogyra muelenbergii 5:311-313 Actinomadura 26:451 Actinomadura hibisca 23:343 Actinomadura melliaura 12:366,368 AT 2433-Az and A2 from 12:366, 368 AT 2433-Bland B2 from 12:366, 368 Actinomadura sp. SF-2370 5:55;12:366 K-252a (SF-2370) from 368 Actinomadura spiralis 25:776 Actinomyces naeslundii 21:607 Actinomyces viscosus 21:613;23:536 Actinomycetes 21:186,263,265;29:230 Actinomycetes strain (LIA-0788) 21:414 Actinoplanes coloradoensis 17:283 Actinoplanes sp. 25:777 K-cells-IL2-activated killer cells 25:273 Actinoplanes sp. 28:147 Actinopyga agassize 21:315
1227
Actinopyga agassizi 7:267,269 holothurins from 7:267,269 Actinopyga echinites 7:269 echinoside A&B from 7:269 Actinopyga mauritiana 7:281 Actinostemma lobatum 21:634 Adenanthera pavonina 29:603 Adiantum spp. 29:573,580 Adocia sp. 25:695,723,861 ;28:674 adociaquinone A from 28:678 adociasulfate from 28:674 from Great Barrier Reef 28:674 structure of 28:674 Aedes aegypti 9:299;26:439 Aegiceras comiculatium 7:176-178,180, 185,195 Aegiceras floridium 7:176-178 Aegilops ovata 26:187 Aegle marmelos 21:599 Aegopodium podagraria 27:687 Aeolanthus suaveolens 22:509,511 in convulsions 22:511 Aeridoteres tristis 5:837 hemogloin components of 5:837 Aerobacter aerogenes 11:183 Aerobacter ganera 29:311 Aeromenas salmonicida 4:197;23:238; 25:259 Aeromonas hydrophila 4:197 Aeropyruin pernix 25:720 Aeschynomene indica 25:93 Aesculus chinensis 29:574,575 Aesculus glabrus 15:191 Aesculus hippocastanum 7:142,143; 21:657,666 escins from 21:666 escins Ia,Ib,IIa and IIb from 21:657 Aesculus indica 7:142,143 aesculosides A,B from 7:142 triterpenes of 7:142,143 Aesculus saponins 15:191 Afraegle paniculata 22:511 as anticonvulsant 22:511 Aframomum hanburyi 27:17,34 3-ac e toxy-5,7- dihydroxy-4 'methoxyflavnone from 27:17,34 Aframomum hanburyi K. Schum. 27:17 Afi"amomum pruinosum 27:34
Aframomum aulacocarpos 25:259,266 Aframomum danielli 25:257,260 Afzelia bipendensis 9:256 bipendensis from 9:256
Agaricus blazei 28:569 isolation of 28:569 mechanism of 28:569 Agastache foeniculum 29:571 Agastache rugosa 29:574 Agathis robusta 25:252 AgatophylIum aromaticum 21:616 Agave cantala 7:427 Agelas sp. 6:28;25:709,712,722,779 agelasins from 6:28 Agelas clathordes 25:860 Agelas dendromorpha 25:792 Agelas dispar 25:706,710,722,777;28:692 from Bahamas 28:692 pyridinebetaine B of 28:692 Agelas marritiana 25:688,722,784,870; 28:689 Agelas mauritianus 18:460,467 agelasphins from 18:460,467 Agelas nakamurai 6:28;25:688,712,780, 860;28:670 agelasin-B from 6:28 agelasidine A from 28:670 agelasidine B from 28:670 antispasmodic activity of 28:670 Na+/K+-transporting adenosine triphosphate (ATP)ase inhibitor from 28:670 Agelas novacaledoniae 25:710 Agelas oroides 21:270;25:703;26:819; 28:690 Agelas sceptrum 21:270 sceptrin from 21:270 Agelas sponge sp. 25:688 Agelas wiedenmayeri 25:712 Agelenopsis aperta 19:675 Ageratina adenophora 5:28 Ageratum fastigiatum 5:728 Ageratum houstonianum 22:395,396 Aglaia elliptica 26:218 aglaiastatin from 26:220 4'-demethoxy-3',4'-methylenedioxy-methyl rocaglate from 26:218 1-oxo-4'-demethoxy-3',4'-methy-
1228 lenedioxyrocaglaol from 26:218 4'-demethoxy-3',4'-methylenedioxyrocaglaol from 26:218 1-O-formyl-4'-methylenedioxymethylrocaglaol from 26:218 Aglaia odorata 22:511 ;26:220 in convulsions 22:511 pyrimidinone from 26:220 rocaglaol from 26:220 Aglaonema treubii 24:917 Aglaophenia pluma 5:353 Agmenellum quadruplicatum 26:358 Agratis ipsilon 7:397 Agrimonia eupatoria 29:581 Agrimonia pilosa 23:396 Agrobacterium aurantiacum 21:299 Agrobacterium radiobacter 21:185 Agrobacterium rhizogenes 15:376,377; 17:395,421; 22:740;26:640,641 Agrobacterium sp. 25:395,659,711,878 Agrobacterium sp. 7:76 Agrobacterium tumefaciens 9:386,388; 21:185 ;22:740;23:267,268;25:395, 399 Agrocybe cylindracea 23:139 Agropyron repens L. 26:696;27:191,216 Agrostemma githago var. githago 26:49 Ailanthus altissima 7:392,394;23:296 Ailanthus grandis 7:369,381 Ajuga decumbens 29:83,111 Ajuga reptans 29:24 Akebia quinata 22:97 Alaria sp. 26:1121 Albizzia sp. 26:1157 Albizzia harveyi 22:511 for epilepsy 22:511 Albizziajulibrissin 25:208;29:603 Albizzia lebbeck L. 22:511 Alcaligenes eutrophus 1:690;4:39;8:299 Alcaligenes faecalis 23:116;25:718 Alcaligenes faecalis var. myxogenes 5:314 Alcyonacea 21:272,279 Alcyonidium gelatinosum sp. 18:695; 28:619,716 (2-hydroxyethyl) dimethylsulfoxonium ion from 28:619 Dogger Bank itch by 28:619 Alectoria sarmentosa 5:310,311 Alectoria sulcata 5:310,311
Alexa leiopetala 11:267;12:332,342; 27:255 (+)-castanospermine from 11:267; 12:332 (+)-6-epi-castanosperime 12:342
( 1S,6S,7R,8R,8aR)-tetrahydroxyindolizidine from 12:332
Alexandrium fundyense 18:703 Alexandrium ostenfeldii 18:703 Alexandrium tamarebnsuis 7:703 Alexandrium tamarensis 17:4;18:703 Ailanthus malabarica 21:273 Allescheria boydii 26:227 Al!ium ascalonicum L. 22:511 Allium cepa 22:511 ;29:341,578,580,589 for epilepsy and infantile convulsions 22:511 Allium macrostemon 21:670 furostanolglycoside from 21:670 Allium sativum L. 22:511,29:684; 23:341,455,481;26:493,796,1135; 28:415 for conculsive affections 22:511 Allium ursinum 29:595,684 (+)-alloaromadendrane-4,10-diol from 14:379 Allolobophora sp. 30:828 from Lumbricidae family 30:828 Allomyces macrogynus 5:276,6:544 Allomyces sp. 5:276 Allopylus africanus 22:511 for convulsions 22:511 Alnus firma 17:359,364 Alnus glutinosa 19:246 Alnus hirsuta 17:360-361 Alnus japonica 17:360,368 Alnus maximoviczii 26:883 Alnus rubra 17:359,26:596 Alnus serrulatoides 17:359-360 Alnus species 17:358-359,368,375 Alocasia macrorrhiza 29:603 Aloe sp. 22:580 Aloe vera L. 22:511 for epilepsy and convulsions 22:511 Alphidium pliciferan 25:895 Alphinia speciosa 21:599 Alpinia sp. 26:905 Alpinia blepharocalyx 26:886,887,902
1229
Alpinia conchigera 26:883 Alpinia galanga 23:800,24:302,25:257,260 Alpinia katsumadai 17:362,375 Alpinia officinarum 17:362-363,375, 26:883 Alpinia oxyphylla 17:362,375,379,24:273 Alpinia sieboldiana 17:362 Alpinia sp. 17:358 Alsidium corallinum 26:479 Alsidium helminthocorton 26:478 Alstonia augustifolia 13:422 Alstonia scholaris 5:135,137,138,13:383 Alstonia boonei 22:512,29:574,583,585, 587 Alstonia constricta 1:125,214-217,219, 2:369 Alstonia macrophylla 5:135,154-157 Alstoniascholaris R. Br. 22:512 for epilepsy 22:512 Alstonia scholaris R. Br. 22:512 Alstonia venenata R. Br. 1:125;22:512 for epilepsy 22:512 Altemaria solani 598 Altenaria kikuchiana 22:273 Altermaria mali 12:400 Alternaria sp. 9:203 Alternaria alternata 21:217;22:263; 24:936;25:305,307,672;26:451 ;27:793; 28:114 diketopiperazines from 24:936 Alternaria cinerariae 11:194 dehydrocurvularin by 11:194 Alternaria helianthi 26:1091 Alternaria kikuchiana tanaka 5:598; 15:385 Alternaria longipes 28:114 Alternaria solani 15:346;25:302,303, 307,316 altersolanol A from Alternaria tenuis 9:300;28:114 Alteromonas luteoviolaceus 21:298 Alteromonas rawa sp. 25:820 Alteromonas sp. 21:411,259;25:717,719 alteramide A from 21:411 Altertogorgia sp. 25:695 Alutera scripta 5:390 Amalhia alternata 25:776 Amanita agaricus 9:203
Amanita muscaria 22:737;23:115,118, 134;29:292 Amanita phalloides 5:496;21:96 Amaranthus caudatus L. 27:217;29:607 Amaranthus hypochondrionacus 29:607 Amaranthus retroflexus L. 27:217 Amata sp. 5:225,252 Amathia alternata 17:85 Amathia convoluta 17:75,18:715;25:786 Amathia genus 17:82 Amathia wilsoni 17:92,95,97,101,18:693; 25:782 Amaurornis phoenicurus 5:83 hemoglobin components of 5:83 Amblyomma sp. 28:394,397 Amblyomma americanum 25:795 Amblyomma hebraeum 28:396 Amblyomma variegatum 28:395 repellent properties of 28:395 Ambrosiasp. 25:138;26:437 Ambrosia maritima 7:427 Ambrosia peruviana 14:379 Amenanthus retroflexus 7:398 Amitermes evuncifer 14:452,463 evuncifer ether from 14:452,463 Amitermes excellens 14:450-452 amiteol from 14:450-452 Amitermes messinae evuncifer ether from 14:452 Ammania baccifera 9:65 sesquiterpenes from 9:65 Ammi sp. 29:579 Ammi majus 23:337 Ammi visnaga 23:352;29:571 Ammophila fernaldi 5:224,232,253 Ammophila nigricans 5:224,232,252 Ammophila procera 5:225,232,252 Ammophila urnaria 5:223,224,232,252 Amomum cardomon 24:272 Amomum compactum 24:274 Amomum xanthiodes 24:272 Amoora 21:124 Amorpha fruticosa 24:225,227 Ampelopsis brevipedunculata 26:551 Ampelopsisjaponica 22:512 as anticonvulsive agent 22:512 Ampelopsisjaponica 22:511 Amphicarpa meridiana 23:273,275 Amphicarpeae edgeworthii 25:93
1230
Amphidinium sp. 5:396,19:559 Amphimedon sp. 21:260;25:709, 710;26:454 Amphimedon complanata 26:90 Amphimedon compressa 21:308 Amphimedon sponge 26:74,88 Amphimedon terpenensis 21:350-352, 363,367 Amphiscolops sp. 5:396 Ampulliferine thunbergii 21:417 (-)-ampullicin from 21:417 (+)-isoampullicin from 21:417 Amsonia elliptica 1:125 Amycolatopsin sp. 28:150 Amyris balsamifera 21:583 Anabaena circinalis 26:367 Anabaena cylindrica 25:717 Anabaena doliolum 26:366 Anabaena genera 27:879 Anabaena sp. 25:794;26:352,354,358, 359,364,365,378,379 Anabaena variabilis 26:366 Anacardium giganteum 9:316 Anacardium occidentale 7:427,1"/:645,34, 9:75,316,318,323,329,332,335,337, 338,340,347 ;21:591 Anacardium semecarpus 9:318 Anacyclus 29:683 Anacyclus pyrethrum 10:162;21:378, 379;24:686,690,705,708, 710,712 anacyclin from 21:378 pellitorine from 10:162;21:378 Anagallis arvensis L. 22:512 for epilepsy and hysteria 22:512 Anagasta kueniella 9:322 Anagyris foetida 2"/:278 Ananas comosus 27:872;29:600 Anas platyrhynchos 5:836 hemoglobin components of 5:836 Anaxagorea luzonensis 28:234 Anchinoe tenacior 25:862;28:715 Anchusa officinalis 17:126 Anchusa strigosa 29:571 Ancistrocerus antilope 5:223,232,253 Ancistrocerus campestris 5:224,252 Ancistrocerus sp. 5:251 Ancistrocladus abbreviatus 20:447 ancistrobrevin B from 20:447 Ancistrocladus alkaloids 20:408,437
Ancistrocladus heyneanus 26:813 Ancistrocladus korupensis 20:442,447; 26:822;27:865 korupensamines A and B 20:442 korupensamines C 20:447 michellamines from 20:442 Ancorina sp. 28:120 Ancylostoma 26:481 Ancylostoma duodenale 26:425,429 Andrena haemorrhoa 19:129,131-132 Andrena ocreata 19:129 Andrena ovatula 19:129 Andrena wilkella 1:692 mandibular gland secretion 1:692 Andrena wilkella 19:129 Androctonus australis 23:341 Androcymbium palaestinum 29:358 Andrographis paniculata 5:678,7:117, 17:472;25:251,270;24:275;29:102, 586-588 Andropogon zizanioides 24:274 Androsace saxifragifolia 15:200 saxifragifolins A and B from 15:200 Androsaemum 30:609,610 Aneilema scapiflorum 22:512 for infantile convulsions 22:512 Anemarrhena asphodeloides 21:668,670; 24:919-922;26:237 ;28:234 in diabetic treatment 24:919 pseudoprototimosaponin AIII from 21:668 prototimosaponin AIII from 21:665 steroidal saponin from 21:670 Anemia mexicana 6:195,202,208 antheridiogens from 6:195,202, 208 Anemia phyllitidis 6:194,202 antheridiogen from 6:194,202 Anethum sp. 29:581,582 Anethum graveolens L. 7:108,109; 29:83;27:379 Angelica archangelica 23:350 Angelica decursiva 23:352;27:835 Angelica furcijuga 25:471,476 Angelica gigas 2"/:835 Angelica keiskei 22:432,29:578,775; 30:55,56
1231
from 22:4-hydroxyderricin chalcones from 30:56 inhibition of catecholamineinduced vasoconstriction by 30:55 use as analeptic 30:72 use as diuretic 30:72 use as lactagogue 30:72 use as laxative 30:72 use in catecholamine-induced vasoconstriction 30:72 use in coronary heart diseases 30:72 use in hypertension 30:72 xanthcangelel from 30:55 Angelica pubescens 26:436 Angelica shikokiana 27:429 Angiostrongylus 26:484 Anguillula aceti 26:450,452,459,464,482 Anguina tritici 26:456 Aniba sp. 8:159 neolignans from 8:159 Aniba canellila 39:117 Aniba neolignans 8:159-163 total synthesis of 8:159-163 Anigozanthos sp. 17:372 Anisakis sp. 26:475 larvae of 26:457,474,475 Annoba montana 26:212,243 syringaresinol from 26:212 (-)-syringaresinol from 26:243 Annona bullata 9:396,397;18:221 Annona densicoma 9:395 annonacin from 9:395 Annona glabra seeds 28:430 Annona muricata L. 17:277;18:213 22:512 for epilepsy convulsive seizures 22:512 Annona squamosa 9:398;28:404,415 extract of 28:415 Annonidium monni 22:512 for epilepsy 22:512 Anochertus sedilloti 5:223-225,238,254 Anogeissus sp. 26:1157 Anogeissus acuminata var. lanceolata 26:224 anolignan A & B from 26:224 Anogeissus latifolius 26:1157
Anona spp. 28:392 Anopheles 26:781,782 Anthemis nobilis 22:679 Anthemis saguramica 30:153,162 Antheraea polyphemus 22:387 Anthocidaris crassispina 25:868 ganglioside GM5 from 18:486
Anthonomus grandis 3:693,7:187,190 Anthopleura elegantissima 2:306, 9:493-495 ;25:873 ;28:647 mycosporine-taurine from 28:647 Anthostoma avocetta 23:229 Anthoxanthum sp. 29:584 Anthracophyllum archer 29:272 Anthracophyllum discolor 29:279 Anthracophyllum sp. 29:283 Anthricus sylvestris 18:555;26:215 anthricin from 18:555 deoxypodophyllotoxin from 26:215 (-)-deoxypodorhizone from 26:215 (-)-hinokinin from 26:215 nemerosin from 26:215 morelensin from 26:215 Anthrobacter citreus 20:234 Anthrobacter sialophilus 27:115 Anthrobacter simplex 20:234 Anthrobacter ureafaciens 16:87 Anthrotaxis spp. 3:456 Antiaris toxicaria 28:203,220 antiarone A from 28:203 antiarone B from 28:203 antiarone E from 28:204 antiarone J from 28:203 antiarone K from 28:203 ficusins A from 28:204 uses for arrow poison 28:203 Apaenogaster rudis 5:254,255 Apergillus oryzae 18:807 monohexosylceramides from 18:807 Aphaenogaster longiceps 5:252 Aphanamyxis sp. 21:124 Aphanizomenon flosaquae 26:353 Aphanizomenon sp. 26:352,358 Aphanocapsa feldmanni 23:367 Aphanomyces 22:493 Aphanomyces cochlioides 22:482 Aphanomyces euteiches 22:482
1232
Aphanomyces raphani 22:482 Aphelandra tetragona 27:191,193 Aphelasterias japonica 15:69 Aphelencoides besseyi 26:434,436,439, 465,469
Aphelencoides tritici 26:438,469 Aphidius rhopalosiphi 27:213 Aphis gossypii 23:666 Aphomia melleus 15:387 Aphomia oniki 15:383 Aphomia sociella 15:384 apigenin-7-O-glucoside from 28:167 bilobetin from 28:166 biological activities of 28:165 chemistry of 28:165 delphidenon from 28:167 ginkgetin from 28:166 ginkgolide A from 28:170 ginkgolide B from 28:170 ginkgolide C from 28:170 ginkgolide J from 28:170 ginkgolide M from 28:170 isoginkgetin from 28:166 isorhamnetin from 28:167 isorhamnetin-3-O-glucoside from 28:167 isorhamnetin-3-O-rutinoside from 28:167 kaempferol from 28:167 kaempferol-3-O-(2"-Oglucosyl)rhamnoside from 28:167 kaemp ferol-3-O-(6"'-O-pcoumaroyl-2"-O-glucosyl) rhamnoside from 28:167 kaemp fero1-3-O-[6"'-0- {p-(7 ....-Ogluc o syl) c oumaroyl }-2"-Oglucosyl]rhamnoside from 28:167 kaemp fero 1-3-O-[ c~-rhamnosyl( 1-~ 2)- ot-rhamno syl- ( 1--+6)]-[3glucoside from 28:167 kaempferol-3-O-glucoside from 28:167 kaemp ferol-3-O-retinoside from 28:167 kaempferol-7-O-glucoside from 28:167
luteolin from 28:167 luteolin-3'-O-glucoside from 28:167 4-O-methylpyridoxine from 28:172 myricetin from 28:167 myricetin-3-O-rutinoside from 28:167 quercetin from 28:167 quercetin-3-O-(2"-O-glucosyl) rhamnoside from 28:167 quercetin-3-O-(6"'-O-pcoumaroyl-2"-O-glucosyl) rhamnoside from 28:167 quercetin-3-O-[6"'-O- {p-(7 ....-Ogluco syl)coumaroyl }-2"-0glucosyl]rhamnoside from 28:167 quercetin-3-O-[6"'-O-p-coumaroyl -2"-O-glucosyl)rhamnosyl-7- Oglucoside from 28:167 quercetin-3-O-[cz-rhamnosyl( 1--~2)- c~-rhamnosyl- ( 1---~6)- [~glucoside from 28:167 quercetin-3-O-glucoside from 28:167 quercetin-3-O-rhamnoside from 28:167 quercetin-3-O-rutinoside (rutin) from 28:167 sciadopitysin from 28:166 Apiosordaria effusa 28:117 Apiospora montagnei 21:216 apiosporamide from 21:216 Apis mellifera 28:387,393 Apium graveolens L. 22:512;29: 83, 573,581,589 Apium sp. 27:686 Apiyski brasiliana 25:702,717,785,801 Aplidium albicans 27:804 Aplidium californicum 10:248;18:716 Aplidium cavernosa 10:248 Aplidium constellatum 10:248 Aplidium genus 25:837 Aplidium meridianum 25:764 Aplidium multiplicatum 23:185,196 Aplidium pliciferum 23:235;28:635 Aplidium sp. 5:440,617;10:244,248 Aplidium uouo 28:644 Aplinia sp. 17:358
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Aplysia sp. 5:368;25:724 Aplysia brasiliana 6:6;9:249;18:625 Aplysia dactylomela 5:368;6:35;17:7,8, 430
Aplysia faciata 17:6 Aplysia fistularis 25:787 Aplysia juliana 17:6 Aplysia kurodai 6:24,56;17:4,6;28:648 Aplysia punctata 17:9;25:769 Aplysilla glacialis 17:14,15 Aplysilla rosea 6:107 Aplysilla sulphurea 17:11 Aplysina aerophoba 21:259,260 aerophobin-1 from 21:259 isofistularin-3 from 21:259 Aplysina aerophoba 25:712 Aplysina archeri 25:720 Aplysina cauliformis 25:766 Aplysina fistularis 17:103 ;21:307,308; 26:8628:697 Aplysina sp. 25:17,707 Apollonias barbujana 26:850 Apuleia leiocarpa 5:679,680 Arabidopsis cultivar 25.'418,419; 26:933,1289 mutant detz 25:419 mutant saxl 25:418 Arabidopsis dwarf 25:414 Arabidopsis thaliana 18:721;25:377,385, 496;27:322,331 ;26:478,945,948,1268, 1289;29:59,603,607,612,613 Arachiniodes exilis 27:35 Arachiniodes sporadosora 27:35 Arachis hypogaea 25:93;29:598 Arachniodes exilis 15:33;27:18,35 Arachniodes sporadosora 15:33;27:18,35 Arachnoideum sp. 26:685 Aralia continentalis L. 22:512 Aralia elata 21:655,666;24:273 triterpene saponins from 21:655 Araliopsis tabouensis 2:121 Araucaria bidwilli 25:249 Araucaria cookii 17:36 Araucaria cunninghamii 17:36 Araucaria excels 25:249 Arbacia lixula 15:104 Arbacia punctulata 7:303 Arbus cantoniensis 25:91 Archaster typicus 7:304-306;15:74,84
Archniodes sporadosora 27:35 Arctium lappa 5:497;26:217,233,241 arctiin from 26:217 arctigenin from 26:217 Arctomecon genera 27:163 Arctuin lappa L. 25:944 Arcyria cinerea 29:236 Arcyria denucata 21:263 arcyriaflavin from 21:266 arcyriaflavin-B from 12:366,370 arcyriaflavin-C from 12:366,370 arcyriarubin A from 12:366,370 arcyriarubin B from 12:366,372 arcyriarubin C from 12:366,372 arcyriaverdin C from 12:366,372 arcyoxepin A from 12:367,373 arcyroxepin B from 12:367,373 arcyroxindole A from 12:367,372 arcyroxocin B from 12:367,372 dihydroarcyriarubin B from 12:366,370 Arcyria denudata 5:55,29:225,236 Arcyria feruginea 29:258 arcyriarubin C from 12:366,372 Arcyria natans 29:236 arcyriacyanin A from 12:366,372 arcyriaflavin-A from 12:366,370 arcyrioxocin A from 12:367,472 dihydroarcyriacyanin A from 12:367,372 Arcyria sp. 12:367,373 arcyrin A from 12:367,373 arcyrin B from 12:367,373 Ardeola ibis 5:837 hemoglobin components of 5:837
Ardisia crenata 26:8 Ardisiajaponica 13:660;17:117,127 Areca catechu 13:660;24:272;29:578 arecoline from 13:660
Arecoline sp. 25:530 Arelia cordota 20:690 Arenaria filicaulis 26:52 Arenaria kansuensis 18:721 Argemone genera 27:163 Argemone mexicana 26:435 Arginomonas non-fermantans 25:155 Argogorytes fargei 5:225,250,253 Argogorytes mystaceus 5:225,231,252, 253
1234
Arisaema amurense 22:512,513 for convulsions 22:513 Arisaema amurense var. serratum 22:512 as anticonvulsant 22:512 Arisaema consanguineum 22:512 for convulsions 22:512 Arisaema grammicola 22:579 Arisaema heterophyllum B. 22:512 for epilepsy 22:512 Arisaemajaponicum 22:513 Arisalema heterophyllum B. 22:512 Aristeguetia bulleaefolia 25:251 Aristolochia argentina 19:494 Aristolochia indica 22:27 aristolactam-N-beta-D-glucoside from 22:27 Aristolochia spp. 21:97 Aristotelia australasica 11:293,317 allo-aristoteline (epi-11aristoteline) from 11:317 aristolasicone from 11:312 (+)-aristoserratenine from 11:293 3-epi-aristoserratenine from 11:293 Aristotelia fruticosa 11:278,324 (+)-aristofruticosine from 11:324 (+)-fruticosonine from 11:278 Aristotelia serrata 11:278,296,301 (-)-aristomakine from 11:301 (-)-aristomakinine from 11:301 (+)-aristoserratenine from 11:293 (+)-aristoserratine from 11:296 (-)-hobartine from 11:278 Arjuno acid triacetate 25:59 Armillaria mellea 5:289,290;22:513 Armillaria nova zelandiae 21:196 Arnica sp. 29:577 Arnica acaulis 29:90 Arnica chamissonis 29:90 Arnica montana 26:808;29:90 Arnica spp. 29:577 Arossostephium chinese L. 22:518 Arrabidaea platyphylla 22:513 for epilepsy 22:513 Artabotrys zeylanicus 20:480 dioxoaporphines of 20:480 Artemia salina 9:385,387;21:257;22:577, 629;23:170;26:703 Artemisia sp. 29:580
Artemisia abrotanum 7:205,218,240 coumarin-sesquiterpene ethers in 7:205 Artemisia absinthium 7:215,219,220,240; 28:425,426 absinthin from 7:215 Artemisia annua 22:146;26:363,783,801, 831 artemisinin from 13:657;20:518 arteannuin B from 7:217 candinane derivatives from 7:217 Artemisia anomala 7:215,240 aurantimide acetate from 7:220 simiarenol from 7:218 Artemisia aragonensis (A. herb alba) 7:212 Artemisia arborescens 27:376 Artemisia arbuscula 7:208 arbusculone from 7:208 Artemisia argyi 7:218 simiarenol from 7:218 Artemisia aucheri 7:208,241 Artemisia austriaca 7:241 C-methylflavone in 7:207 Artemtsla californica 20:4 Artemtsla cantabrica 7:216,242 Artemlsla capillaris 7:220,242;23:341 Artemlsta carvifolia 7:206,242;29:574 Artemlsta compacta 7:205,243 Artemtsla douglasiana 7:203,204,217, 218,243;29:90 Artemisia dracunculus 7:220,243;29:577 Artemisia family 25:944 Artemisia feddei filifolide A from 7:208 filifolone from 7:208 Artemisia fragrans 7:208,244 Artemisia genus 27:376 Artemisia glutinosa 7:220,244 Artemisia gypsacea 7:211,245 Artemisia herba alba 7:212,217,245; 17:475;24:65,79;27:376 Artemisia hispanica 7:216 elemanolide from 7:216 2~-hydroxyartemorin from 7:211 tamaulipin A from 7:211 Artemisia inculta 7:217,245 Artemisia iridentata ssp. rothrockii 7:208,252
1235
Artemisiajudaica 7:211,216,217,246; 27:376 Artemisia klotzchiana 7:214,246 Artemisia koidzumii 7:218,246 Artemisia laciflora 7:203,218,246 Artemisia laciniata 7:215,216,246;9:529, 531,533-535 Artemisia lanata 7:214,246 Artemisia latifolia 7:219,247 Artemisia leucodes 7:215,247 Artemisia longloba 7:218,247 Artemisia ludoviciana 7:203,247;29:87 Artemisia maritima 7:217,427;13:660; 24:54,77 Artemlsla marschalliana 7:220,248 Artemtsla molinieri 7:218,248 Artemisia monosperma 7:204,220,248 Artemtsta montana 25:944;27:418 Artemisia moorcroftiana 9:529,530,534 Artemlsta pallens 7:217,249;9:531 Artemlsta palustris 7:207,220,249 Artemtsta pectinata 7:214,216,249 Artemlsta persica 7:217,249 Artemisia princeps 25:944;27:418;29:87 Artemisia roxburghiana 7:219,250 Artemisia rupestris 7:218,250 Artemtsta rutifolia 7:215,250 Artemtsta salsolodes 9:529-531,533,534 Artemista santolina 7:212,250 Artemisla santonicum 7:212,250 Artemisia schmidtiana 14:450 eudesm-11-en-4-ols from 14:450 neointermedeol from 14:450 Artemisia selengensis 7:203,204,215,251 Artemisia sp. 7:201-263;9:529-536; 27:418,847;29:88 Artemisia szowitziana 7:216,251 Artemisia toumefortiana 7:212,252;24:79 Artemisia tridentata 28:408 Artemisia umbelliformis 7:215,253 Artemisia valentina 7:213,218 Artemisia verlotorum 22:513 Artemisia vulgaris 7:120,208,215,218, 253 Artemisia xanthochroa 7:215,253 Arthrobacter globiformis 9:418;26:1263, 1268-1270,1272,1278-1280 Arthrobacter ilicis 25:719 Arthrobacter simplex 9:418,427,428
Arthrobacter sp. 26:1122,1124 Arthrobotrys oligospora 26:431,432,449 Artocalpus altilis 28:202 Artocarpus communis 28:202;29:706 Artocarpus elasticus 29:790 Artocarpus helerophyllus 22:513;29:580 as sedative for convulsions 22:513 Artocarpus heterophyllus 27:842;28:202 Artocarpus nobilis 2:231 Artocalpus rigida 28:202 Artocatpus sp. 28:203 Artocarpus venenosa 28:202 artobiloxanthone from 28:202 artonin E from 28:202 cycloartobiloxanthone from 28:203 isoprenylated flavonoids from 28:202 use against inflammation 28:202 use in malarial fever 28:202 use as folk medicine 28:202 Arxulla adeninivorans 25:150 Asarum maranthuym 22:513 for hysteria 22:513 Asarum maranthuym 22.513 Ascaridia galli 26:457,484 Ascaris sp. 26:463,478 Ascaris lumbricoides 23:837;26:425,429 Ascaris suilla 26:443 Ascaris suum 26:443,450,477 Ascidia mentula 28:642 heneicosane- 1,21-diyl disulfate from 28:642 3,7,11,15-tetramethylhexadecane1,19-diyl disulfate from 28:642 Ascidia nigra 10:241;23:242 Asclepias curassavica 5:249 Asclepias fruticosa 5:248,249 Asclepidaceae sp. 27:3 Ascobolus furfuraceus 5:279;21:209,228, 235 Ascochyta viciae 21:227;26:797 Ascocoryne sarcoides 29:266 Ascomycota sp. 22:246 Asiasari radix 21:378 Asiasarum heterotropoides 21:378 Asiasarum hetrotropoides var. madshuricum 24:228-232;26:226 asarinin from 26:212,226
1236
xanthoxylol from 26:212,226
Asiasarum sieboldii 21:378 Asimina tiloba 9:391 Aslcaligenes eutrophus 25:162 Aslchyta rabiei 26:1288 Asltonia macrophylla 13:383,422 Asltonia muelleriana 13:383,399,422 Aspalathus linearis 28:272 Asparagopsis sandfordiana 9:83-85 marine sterols from 9:83-85
Asparagus sp. 17:130;25:37 Asparagus africanus 26:230,813 Asparagus cochinchinensis 17:116117,130.132
Asparagus curillus 7:427 Asparagus officinalis L. 21:636,662; 25:377 ;26:477 ;22:513
Asparagus plumosus 7:427 Asparagus recemosus 22:513 as anticonvulsant in epilepsy 22:513 Aspergillus aculeatus 23:343 Aspergillus acylase 1:678 Aspergillus alleaceus 20:792 Aspergillus arenarius 29:282,292 Aspergillus awamori 2:322,341,353 Aspergillus brevipus 12:400 Aspergillus caespitosus 19:480 Aspergillus campestris 29:269,281 Aspergillus candidus 29:267,268,270,281 Aspergillus cellulosae 25:150 Aspergillus cladosporoides 26:228 Aspergillus clavatus 21:240 patulin from 21:240 Aspergillus deflectus 23:343 Aspergillus duricaulis 15:343,345 Aspergillus flavus 2:446;5:296;9:300; 15:386,245;18:711 ;26:228;27:225, 382;28:128,476 Aspergillus fumigatus 5:295-298,322, 326;7:65 ;9:300;12:400;18:469,807, 809;21:237 ;22:261 ;23:4,5 ;25:764; 26:228,458,673,1093,1128 helvolic acid from 21:237 Aspergillus melleus 15:383;21:211; 26:449 Aspergillus nidulans 5:295,296;21:188; 22:263,476;23:240;25:301,321
Aspergillus niger 21:217,240,396,599; 22:627;23:349;25:136,140-143,145, 148,149,152-155,157,158,165,166, 168,172,173,777 ;26:228,307,971, 1141,1144,1263,1268,1278,1280, 1283,1286,1287 ;27:382 ;29:548; 30:431,739 c~-L-rhamnosidase from 7:70 [~-glucosides from 7:51,52,55, 56,65-67 antibacterial activity against 30:739 antifungal activity against 30:739 cycloisomerase from 8:296 3-deoxy-2-keto-gluconate (KDG) aldolase from 30:431 glucoamylase from 7:62 isozyme I from 2:322,341 lactone from 8:300 metabolic function of 30:431 Aspergillus niger H7160B 28:476 Aspergillus nomius 28:128 Aspergillus ochraceus 15:387;21:211; 25:139;27:382 ochratoxins from 15:387 Aspergillus oryzae 1:697,117;2:322, 341 ;5:295 ;6:551,552;13:304 ;21:238; 25:780;26:1007 Aspergillus parasiticus 22:266;27:382; 28:128 averufin by 11:194 Aspergillus sp. 2:323 ;5:276,278,294,301, 325,5:326,328,368,370;9:203,300; 21:196,204,233,239;22:57,248,251; 25:150,151,156,729;26:450,491 glucoamylase from 2:322 Aspergillus stellatus 10:439 (+)-asteltoxin from 10:439 Aspergillus taichungensis 29:269 Aspergillus tamarii 28:128 Aspergillus terreus 5:296,730;15:385; 19:168 ;21:212,233,240,239;22:627; 26:1281 ;30:220,431 patulin from 21:240 butyrolactone II from 30:220 Aspergillus versicolor 18:807,809 Aspergillus wentii 7:56,64;9:30028:454, 465 Asperula sp. 26:631
1237
Asphaenogaster rudis 5:226,243-245 Aspicularis tetraptera 26:493 Aspidosperma cyclindocarpon 19:112 Aspidosperma marogravianum 1:124 Aspidosperma oblongum 1:124,125 Aspidosperma olivaceum 26:144 Aspidosperma quebrachoblanco Schlecht 29:362
Aster batangensis 21:673 asterbatanoside F from 21:673
Aster spathulifolius 25:251 Aster tataricus 24:339 Asteraceae family 22:396 Asteremyces cruciatus 25:828 Asteria pectinifera 7:307 Asterias amurensis 7:286-298,303;15:44 Asterias amurensis vesicolor 7:287 asterosaponin-1 from 7:287 thornasteroside A from 7:287 versicosides (A-C) from 7:287 Asterias forbesi 7:288;15:58,69;28:718 Asterias rubens 6:151,152,156,161; 7:288,294,304,306;15:48 Asterias vulgaris 7:288,291,304;15:59; 28:718 Asterina pectinifera 7:289;15:44,48,55; 25:698 Astichopus multifidus 7:272,273,281 astichoposide C from 7:273 Astilbe chinensis 27:395 Astilbejaponica 27:395 Astilbe revularis var. rivularis 27:395 Astilbe thunbergii 27:395 Astragali radix 27:443,445,507,513 Astragali semen 27:478 Astragallus genus 25:188,190 Astragallus sp. 25:180,183,186,187,190, 219;27:253 Astragalus adsurgens 25:184;27:478,450 Astragalus aitosensis M.B 27:449,450, 511 Astragalus alexandrinus 25:184,189,192, 193,214,224;27:454,476,477,500,505 Astragalus alopecuros 25:184,201; 27:449,452 Astragalus amarus 25:194,195 Astragalus angustifolius 27:466 Astragalus babatagi 25:184 Astragalus basineri Trautv. 25:184,194
Astragalus bethlehemiticus 25:188,189 Astragalus boeticus 25:192 Astragalus bisulcatus 27:516,527,528 Astragalus brachycentrus 27:454;30:405, 411 antiviral activity of 30:405 tragacanthin polysaccharide (PS) from 30:411 Astragalus bungeanus Boiss 27:453 Astragalus breachypterus 25:184,192, 193,197 Astragalus canadensis L. 27:444,522 Astragalus caryocarpus 27:444 Astragalus centralpinus 27:505 Astragalus cephalotes 25:184,197; 27:454,455 Astragalus cibarius 27:522 Astragalus collinus 27:522 Astragalus coluteocarpus 25:184,192 Astragalus complanatus 25:93,184,203, 204 ;27:445,453,477,478,481 Astragalus complanatus R. 27:453 Astragalus convallarius 27:525 Astragalus crotolariae 27:528 Astragalus da~yanthus Pall. 27:451 Astragalus dissectus 25:184,192;27: 440,449 Astragalus echianaeformis 30:405,411 antiviral activity of 30:405 tragacanthin polysaccharide (PS) from 30:411 Astragalus echidnaeformis 27:514 Astragalus edulis 27:444 Astragalus emoryanus 12:313 (-)-swainsonine from 12:313 Astragalus ephemerotum 25:184;27:449 Astragalus ernestii 25:184,195 Astragalus exilis L. 25:184 Astragalus falcatus 25:196;27:511 Astragalus flexuosus 27:522 Astragalus floccosifolius 27:504 Astragalus furcijuga 25:472 Astragalus galegiformis L. 25:184,196; 27:450,470 Astragalus genera 27:523 Astragalus genus 27:470 Astragalus glycyphyllos L. 25:184,203; 27:444,453,466,477
1238
Astragalus gummifer 25:188;27:444, 499,511
Astragalus hamosus L. 25:184 Astragalus illiensis L. 25:184,195 Astragalus kuhitangi 25:184,192,194; 27:455
Astragalus kahiricus 25:189 Astragalus kulabensis 25:184;27:449 Astragalus kurdicus 27:511 Astragalus lasioglottis 27:505 Astragalus lentiginosus 7:11,486; 27:251,515,524,517 (-)-swainsonine from 12:313 Astragalus lusitanicus 27:524 Astragalus melanophrurius Boiss 25:184, 192,25:193,194,197 ;27:455,482 Astragalus membranaceus Bunge 22:97;
24:145;27:450;25:184,192,25:193,194,
195,205,219,220,221 ;27:443,445,467,4 68,505,511,446,468,470,481-483, 500,506,508,513,665 Astragalus microcephalus willd 25:184, 193,200;27:450 Astragalus miser 27:525 Astragalus miser var. oblongifolius 27:519 Astragalus miser var. serotinus 27:521 Astragalus mollissimus Torr. 27:444 Astragalus mongholicus Bunge 25:184, 192,193,194,202,219;27:448,508;27:4 48,454,467,503,504,508,511 structure of 27:504 Astragalus oleifolius DC 25:185,199; 27:448 Astragalus onobrychis 27:453,466,504, 480 Astragalus orbiculatus 25:185,202; 27:452,515 ' 1-hydroxyindolizidine from 27:515 1,2-dihydroxyindolizidine from 27:515 Astragalus pamirensis 25:185,192,197, 200,202,203 ;27:449 Astragalus pattersonii 27:528 Astragalus pectinatus 27:528 Astragalus penegrinus Vohl 25:185, 195,216,225 Astragalus polycanthus 27:517
Astragalus praelongus 27:516 Astragalus pterocarpus 25:185,192, 193;27:525
Astragalus pterocephalus 27:449 Astragalus pycnanthus 25:185,193,198; 27:450
Astragalus quisqualis Bunge 25:185; 27:450;27:450,504
Astragalus racemosus 27:528 Astragalus severtzovii 27:478 Astragalus shikokianus 27:453 Astragalus siculus 27:482 Astragalus sieberi 27:470 Astragalus sieversianus 27:449,478,480, 481,483
Astragalus sinicus 27:453,511 Astragalus sp. 7:23;25:179;27:253,447, 454,502 biological activity of 27:443 Astragalus spinosus 21:664;27:468,483 astragaloside II from 21:664 Astragalus spp. 27:454-465,474,478,483, 498,500,503,511,519,520,521,523, 745 of Leguminosae 27:519 of saikosaponin 27:671 Astragalus subrobustus 27:504 Astragalus tashkendicus 27:454 Astragalus tibetanus 27:517 Astragalus toanus 27:516 Astragalus tomentosus 27:451,473 Astragalus tragacantha Habl. 27:448,454 Astragalus trigonus DC 27:448,500,505 Astragalus trojanus Stev. 27:453,454,479 Astragalus wootoni 27:516 Astropecten aurantiacus 15:104;15:61 Astropecten indicus 5:214;7:299 Astropecten latespinosus 7:288;15:48 Astropecten polyacanthus 7:306;18:725 Astropecten scoparilis 15:68 Atalantia ceylanica 13:348,349,356 1,5-dihydroxy-3-methoxy- 10methylacridin-9-one from 13:348,350 11-hydroxynoracronycine from 13:348,349,356 11-O-methylatalphilidine from 13:348,349
1239 N-methylatalphyllinine from 13:348,349 Atalantia monophylla 13:348-350 atalphyllidine from 13:348,349 atalphylline from 13:350 atalphyllinine from 13:349 N-methylatalphylline from 13:350 Atractylis gummifera 20:8 A tractylodes japonica 29:88 Atractylodes lancea 24:877,878,883, 29:694 Atropa belladonna L. 20:135;22:721,734, 742,8 Atropa genus 17:395 Atropa sp. 21:104,488 Atta cepholotes 22:66 2,5-dimethyl-3-ethyl-pyrazines of 5:222 Atta sexdens rubropilosa 5:222;26:186 2,5-dimethyl-3-ethyl-pyrazines of 5:222 Atta sexdens sexdens 5:222 2,5-dimethyl-3-ethyl-pyrazines of 5:222 Atta texana 5:234,125 Atuna racemosa 29:708 Aulacohora femoralis chinensis 18:771 Aulacophora femoralis 23:66 Aureobasidium pullulans 5:307,308,314; 21:396 ;22:248 ;23:343 Aureobasidium sp. 5:307 Auricularia sp. 5:287,317,320 Austrocedru chilensis 19:405 Austrovenus stutchburgi 25:864;28:656 brevetoxin BI from 28:656 Auxarthron unberium 25:794 Avena fatua L. 27:215-217,218 Avena sativa 9:220;23:341;27:216-218 Avena strigosa L. 27:215 Averrhoa carambola 22:359;23:785 Avicennia alba 7:176,181,182,189,195 A vicennia germinas 7:175 Avicennia marina 7:176,180,183,184, 194,195 Avicennia officinalis 7:176,181,182, 189,195 Avicennia resinifera 7:193 Avicennia sp. 7:176 Avicennia tomentosa 7:189
Avrainvillea longicaulis 25:787 Axinella 25:847 Axinella canabina 6:5 axamide-1 from 6:5 axisonitrile-1 from 6:5 Axinella cannabina 21:329,349,364; 25:848,852,85328:658 axisothiocyanates from 28:658 axisothiocyanate 2 from 28:658 axisothiocyanate 3 from 28:658 axisothiocyanate 4 from 28:658 sesquiterpenoid from 28:658 Axinella carteri 21:254,270;25:714 Axinella sp. 21:270;25:705 Axinella verrucosa 21:270 Axinella weltneri 25:700 Axinellida order 28:658 Axinyssa 25:694,847,848,859 Axinyssa (Trachyopsis) aplysinoides 25:852,853,858 Axinyssa aplysinoides 21:354 Axinyssa fenestratus 25:852;26:463,464; 28:662 10-isothiocyanato-4,6amorphadiene from 28:662 4-isothiocyanato-9-amorphene from 28:662 10-isothiocyanato-5-amorphen-4ol from 28:662 Axinyssa. sp. 21:351,353,355,356, 359,364,366,367;28:661 Azadirachta indica 9:293-311 ;13:644; 15:384 ;22:95 ;26:466,814;28:388,395, 389,401,401,404,414,573,581 azadirachtin from 26:466 Azomonas macrocytogenes 19:814 Azospirillum lipoferum 4:197 Azotobacter vinelandii 26:1151,1152, 1211
Babesia bigemina 28:398 Babesia bovis 28:398 Babesia sp. 26:694,835;28:398 Babylonia japonica 11:724 Baccharis sp. 29:580 Baccharis anomala D.C. 750 microsomal activation by 30:750
1240 Baccharis articulata 15:22 30:706,708, 723,743,744,750 articulin from 30:708 as antidiabetic 30:706 as decoctions 30:706 as infusions 30:706 bacchotricuneatin A from 30:708 barticulidiol from 30:708 [3-caryophyllene from 30:723 in treatment of rheumatism 30:744 in ulcers 30:744 inhibition of viral infectivity by 30:743 neo-clerodane type 30:708 nerolidol from 30:723 use as raw material for preparation of phytotherapeutic drugs 30:750 Baccharis boliviensis 30:711,712,730,742 coumaric acids 30:730 ent-clerodane derivatives from 30:711 ent-clerodane furanoditerpenoid 30:from 30:711 labdane-type diterpenes from 30:712 structure of 30:730 trypanocidal effect of 30:742 Baccharis calliprinos Grised 30:746 Baccharis calvescens D.C. 30:731 p-hydroxyacetophenones from 30:731 structure of 30:731 Baccharis cassinaefolia 30:708 bacchotricuneatin A from 30:708 Baccharis conferta 30:704,740,748 against Escherichia coli 30:740 as laxative 30:705 for stimulating urination 30:705 in treatment of baldness 30:705 in treatment of gastrointestinal illnesses 30:748 in treatment of insect bites 30:705 in treatment of stomach aches 30:704 triterpenoid oleanoic acid methyl ester from 30:740 Baccharis cordifolia 22:348;30:705, 717,719,733,751 ;30:743,745
as anti-inflammatory 30:705 baccharinoids from 30:717 extract of 30:733 in toxic disease 30:751 in treatment of horse's external parasites 30:705 macrocyclic trichothecenes from 30:743 roridins from 30:717,751 schottenol glucoside 30:719 to treat horse's distemper 30:705 toxins from 30:751 ursolic acid from 30:719 uvaol from 30:719 verrucarins from 30:717 Baccharis cordobensis 30:722 cadinol from 30:722 cubenol from 30:722 essential oil from 30:722 nerolidol from 30:722 Baccharis crispa 30:722,723,739, 743,744,745,750 antibacterial activity against 30:739 antifungal activity against 30:739 essential oil from 30:722 in treatment of liver diseases 30:744 nerolidol ~:om 30:722 phytothe..peutic drugs 30:750 Baccharis dracunculifolia 30:723,730 dracunculifosides A-J from 30:730 Baccharis floribunda 30:706 Baccharis gaudichaudiana 25:251,269; 27:14,24,25 ;30:706,734 as antidiabetic material 30:706 arabinoside gaudichaudioside A from 15:21 as decoction 30:706 as infusion 30:706 gaudichandioside A from 27:14, 24,25 in P-388 lymphocytic leukemia cells 30:734 Baccharis genistelloides 25:941 ;30:706, 711,720,733,739,740,743,744,746,748, 749,750
1241 against HSV-1/VSV 30:743 against Staphylococcus aureus 30:739 anti-inflammatory constituents from 30:746 against Candida albicans 30:739 against gram-positive bacteria 30:739 antimicrobial activity of 30:740 antimutagen constituents from 30:733 apigenin from 30:733 as anti-inflammatory material 30:750 as antithermic 30:706 cirsimaritin from 30:733 diterpene lactone from 30:740 effects on bile duct 30:750 effects on bone marrow 30:750 effects on cardiac function 30:750 effects on liver 30:750 effects on pancreas 30:750 effects on serum lipids 30:750 genkwanin from 30:733 hispidulin from 30:733 in anaemia 30:706 in diabetes 30:706 in diarrhoea 30:706 in digestive disorders 30:706 m indigestion 30:706 m inflammation 30:706 in intestinal worms 30:706 m leprosy 30:706 in liver disorders 30:706,733,749 in malaria 30:706 in rheumatism 30:733 m sore throat 30:706 in tonisilitis 30:706 m ulcers 30:706 in urinary disorder 30:706 [3-sitosterol from 30:720 stigmasterol from 30:720 structure of 30:739,740 structure-activity relationship of 30:733 use in liver diseases 30:749 use in wounds 30:744 Baccharis genus 30:707,733,738 antibacterial activity of 30:738
antifungal activity of 30:738 constituents of 30:707,733 diterpenoids from 30:733 epi-methyltrineracetal from 30:707 flavonoids from 30:733 methyltrineracetal from 30:707 neo-clerodane type diterpene 30:707 secondary metabolites from 30:738 Baccharis glutinosa 30:704,739 antimicrobial activity of 30:739 as contraceptive 30:704 for digestive disorders 30:704 for gynecological disorders 30:704 for skin diseases 30:704 in treatment of infectious diseases 30:739 in weight reduction 30:704 to clean wounds 30:704 to treat scalp diseases 30:704 Baccharis grisebachii 30:705,730,733, 739,745 coumaric acids from 30:730 3-(3,3-dimethylallyl)-p-coumaric acid from 30:730 extract of 30:733 for decoctions 30:705 for poultices 30:705 for wound healing 30:705 inhibitory activity of 30:745 spectrum of action of 30:739 Baccharis halimifolia L. 30:718 baccharis oxide from 30:718 Baccharis heterophylla 30:718 oleanolic acid from 30:718 Baccharis incarum 22:352;30:709,744 bincatriol from 30:709 3'-methoxycalicopterin 7'-methylsudachitin from 22:352 neo-clerodane diterpenoid from 30:709 Baccharis intermixta Gardn. 713 Baccharis L. 704 biological activities of 30:704 traditional uses of 30:704 Baccharis latifolia 30:721,731 oil from 30:721
1242
p-hydroxyacetophenones from 30:731 structure of 30:731 Baccharis macraei 30:710 clerodane derivatives of 30:710 hardwickiic acid from 30:710 hautriwaic acid from 30:710 Baccharis magellamica (Lam.) 30:731 p-hydroxyacetophenones from 30:731 propiophenone derivative 30:731 structure of 30:731 Baccharis medullosa 30:712,744 as anti-inflammatory material 30:744 Baccharis megapotamica 30:717,736,751 activity against P-388 leukemia 30:736 against human carcinoma 30:736 as cytotoxic agents 30:717 baccharin from 30:736 baccharinoids from 30:717 baccharinol from 30:736 bioassay-guided fractionation of 30:736 extract of 30:736 isobaccharin from 30:736 isobaccharinol from 30:736 roridins from 30:717 toxins from 30:751 verrucarins from 30:717 Baccharis multiflora 30:705,713 against catarrhs 30:705 as infusion 30:705 ent-kaurenic acid from 30:713 ent-kaurenol from 30:713 for urinary problems 30:705 kaurane-type diterpenoids from 30:713 Baccharis myriocephala D.C. 750 Baccharis myrsinites 30:709,718,729 clerodane diterpenoid from 30:709 coumaric acid from 30:729 maniladiol from 30:718 oleanolic acid from 30:718 structure elucidation of 30:709 Baccharis myrtilloides 30:723 germacrane D from 30:723
Baccharis notosergilla 30:705,739,740, 742,743 against gram-positive organisms 30:740 against Trypanosoma cruzi 30:742 antibacterial activity of 30:739,740 antifungal activity of 30:739 as digestive agent 30:705 as diuretic 30:705 essential oil of 30:740 in folk medicine 30:705 Baccharis oxydonta 30:711,728 ent-labdane diterpenes from 30:711 pinobanksin from 30:728 pinocembrin from 30:728 Baccharis paniculata 30:710,712,731,740 acetylenic lactones from 30:731 against phytopathogenic fungi 30:740 for antifungal activity against 30:human pathogens from 30:740 3-methyl ether flavone 30:740 neo-clerodane diterpenoids from 30:710 prenylated coumarin from 30:740 Baccharis pedunelata 25:251 Baccharis petiolata 25:251 Baccharis pingraea 30:712 furolabdane diterpenoids from 30:712 furolabda-6,8-dien- 17-oic acid 30:from 30:712 furolabda-7-en-17-oic acid from 30:712 Baccharis pteroniodes 30:711 ent-clerodane diterpenoids from 30:711 neo-clerodane diterpenoids from 30:711 Baccharis ramoisissima 30:713 ent-kaurenic acid from 30:713 ent-kaurenol from 30:713 Baccharis rhetinoides 30:746 anti-inflammatory flavonoids from 30:746 homoeriodictyol from 30:746 Baccharis rubricaulis 30:706 for treating mucous ailments 30:706
1243
Baccharis rufescens 30:723,744 as anti-inflammatory agent 30:744 limonene from 30:723 nerolidol from 30:723 Baccharis salicifolia 30:705,707,718, 721,722,731,732 baccharis oxide from 30:718 ent-clerodane derivatives from 30:707 essential oil from 30:722 for diarrhoea 30:705 for dysentery 30:705 for inflammation 30:705 germacrane D from 30:722 oils from 30:721 prenyl derivatives from 30:731 structure of 30:732 Baccharis salicina 30:715 bacchariolides from 30:715 chemical analysis of 30:715 guaianolides from 30:715 Baccharis santelicis 30:709 Baccharis sarothroides 30:705,710,733 centaureidin from 30:733 cytotoxic flavonols from 30:733 3,4 '- dime thoxy- 3 ',5,7trihydroxyflavone from 30:733 hautriwaic acid from 30:710 2~-hydroxyhautriwaic acid from 30:710 identification of 30:733 inhibitory activity against human carcinoma 30:733 Baccharis scoparia 25:251;30:711,712 labdane aldehyde from 30:712 structure of 30:712 Baccharis serraefolia 30:705,720,739, 748 against Candida albicans 30:739 against Staphylococcus aureus 30:739 against gram-positive organisms 30:739 mechanism of action of 30:748 phytol from 30:720 [3-sitosterol from 30:720 spasmolytic action of 30:748 to treat diarrhoea 30:705
use in gastrointestinal illnesses 30:705 Baccharis spartioides 30:715,723 essential oil of 30:723 spartidienedione from 30:715 Baccharis species 30:706,707,711,750 acetylenic compounds of 30:706 baccharis oxide from 30:706 diterpene derivatives of 30:706 essential oils from 30:706 for preparation of phytotherapeutic drugs 30:750 labdane derivatives of 30:706 parts of 30:707 sesquiterpenes from 30:706 toxicological evaluation of 30:750 used as raw material 30:750 Baccharis sphaerocephala 30:715 amorphane sesquiterpene y-lactol from 30:715 O-methylbaccharocephol from 30:715 Baccharis spp. 30:737,740,741 antineoplastic activity of 30:737 apigenin from 30:740 assay-guided fractionation of 30:737 genkwanin from 30:740 pentacyclic triterpenoids from 30:737 structure of 30:741 Baccharis sternbergiana 30:712 Baccharis timera 7:427 Baccharis tola 30:714,725 ent-4c~-hydroxy- 19-norbeyer- 15ene from 30:714 ent-beyer- 15-en- 17,19-ol from 30:714 ent-beyerane-type diterpenoids from 30:714 flavone from 30:725 Baccharis tricuneata 30:706,708,719 (~-amyrin acetate from 30:719 bacchotricuneatin A from 30:708 for diabetes from 30:706 for skin infections 30:706 friedelin from 30:719
1244
[3-sitosterol from 30:719 ursolic acid from 30:719 Baccharis trimera 30:706 as antithermic agent 30:706 for digestive disorders 30:706 for liver disorders 30:706 use in anaemia 30:706 use in diabetes 30:706 use in diarrhoea 30:706 use m indigestion 30:706 use m inflammation 30:706 use in intestinal worms 30:706 use m leprosy 30:706 use m malaria 30:706 use m sore throat 30:706 use in tonsilitis 30:706 use in ulcers 30:706 use m urinary diseases 30:706 Baccharis trinervis 30:705,725,743 against human immunodeficiency virus 30:743 antiviral activity of 30:743 apigenin from 30:725 flavones from 30:725 flavonol from 30:725 for gastrointestinal disorders 30:705 in dizziness 30:705 in MT-2 infected cells 30:743 in treatment of edema 30:705 in treatment of high fever 30:705 in treatment of muscle cramps 30:705 in treatment of sores 30:705 in treatment of typhoid fever 30:705 inhibition of HSV-1 30:743 pectolinaringenin (5,7-dihydroxy6,4'-dimethoxyflavone) from 30:725 pedunletin (5,4 '-dihydroxy-3,6,7trimethoxyflavone) from 30:725 salvigenin (5-hydroxy-6,7,4'trimethoxyflavone) from 30:725 Baccharis triptera Mart 30:749 in gastrointestinal disorders 30:749 in gastrointestinal hyperactivity 30:749
Baccharis tucumanensis 30:705,733,744 anti-inflammatory action of 30:745 as abortive agent 30:705 extract of 30:733 in carrageenan foot edema test 30:745 role in croton oil induced mouse ear edema test 30:745 Baccharis uncinella D.C. 30:723 essential oil from 30:723 Baccharis vaccinoides 30:705,710,739 against Candida albicans 30:739 against Staphylococcus aureus 30:739 antimicrobial activity in vitro 30:739 for gastrointestinal disorders 30:705 hautriwaic acid from 30:710 2[3-hydroxyhautriwaic acid from 30:710 Baccharis varians 30:728,729 3-acetoxyflavanones from 30:728 Bacillus acidcaldarius 23:92 Bacillus antharacis 12:400 Bacillus aurantinus 5:601 Bacillus cereus 7:413;22:273,274;23:344, 473 ;25:259;26:1091 Bacillus ganera 29:311 Bacillus macerans 27:8,365 Bacillus marinus 23:258 Bacillus megaterium 10:585;12:104; 23:76;27:365 Bacillus pumilis 7:70,308,390;30:693 Bacillus sp. 12:103;21:391,599;25:155 Bacillus stearothermophilus 29:266 Bacillus subtilis 5:302,304,368,418,308, 353;8:353;10:117,104,400,345,692, 290,556,559;18:778;21:237,262,266, 267,284,610;22:627,628;23:41,344, 473 ;24:713 ;25:220,258-260,765, 770,776-779,782,789,792,863; 26:79,333,334,1093 ;28:223, 693 ;29:272;30:693,738 antifungal activity against 30:738 effects of phenols on 28:223 Bacillus thiaminolyticus 15:390 baciphelacin from 15:390
1245
Bacillus thuringiensis var. kurstaki 28:404 Bacopa monnira L. 22:513;23:489,499 for epilepsy 22:513 Bacterium pseudomonas 9:322 Bacteroides fragilis 14:107 Baekhousia citriodora 25:132 Bai-yun-shen 1:666 baiyuoside from 1:666 Balanites aegyptiaca 7:426 Balanocarpus zeylanicus 23:547 Balanophora elongata 29:583,586 Balanophorajaponica 1:666 balanophonin from 20:642 Balanus amphirib 25:783,784,785 Balanus amphitrite 21:366 Ballota nigra 30:268 flavonoids from 30:268 Balsamodendron mukul 5:695 Balsamodendron sp. 22:513 for epilepsy 22:513 Banksia grandis 19:246 Baphia nitida 21:616 Barbilophzia hatcheri 5:730 Barbilophzia lycopodioides 5:730 Barosma betuling 27:375 Barosma crenulata 27:375 Barringtonia acutangula 7:132 barrigenic acid from 7:132 barringtonic acid from 7:132 barrinic acid from 7:132 tangulic acid from 7:132 Barringtonia racemosa 7:132;22:514 barringtogenic acid from 7:132 for epilepsy 22:514 Barringtonia sp. 7:132,133 triterpenes of 7:132,133 Barringtonia speciosa anhydrobartogenic acid from 7:132 bartogenic acid from 7:132 19-epi-bartogenic acid from 7:132 Basidiomycetes 9:220,317 Basidiomycota 22:246 Basilicum polystachyon 22:514 for sedative in convulsions and epilepsy 22:514 Batzella sp. 25:708,760,774,790,822,852; 27:881;28:715
Batzella sponge 28:685 Bauhinia bauhinioides 29:603 Bauhinia microstachya 29:573 Bauhinia mollis 29:603 Bauhinia pentandra 29:603 Bauhinia variegata 29:603 Bazzania 21:281 Beauvaria bassiana 23:20,21,34; 28:397,404 Beesia 25:180 Begonia plebeha 19:764 Belemnitella species 13:330 Bellis perennis 21:662 Bemangovitra 26:1037,1038 Benincasa cerifera savi 22:514;24:273 for epilepsy 22:514 Benincasa hispida 22:513 use for epilepsy and hysteroepilepsy 22:513 Berberidaceae family 27:754 Berberis koetineana 11:202 Berberis sp. 7:88 berberine from 7:88 Berberis stolomifera 20:292 Berberis vulgaris 13:660;25:476 Bersama abyssinica 22:514 Beta vulgaris 15:3;20:721,731,740; 21:666 betavulgarosides from 21:666 Betula davurica 26:895 Betula ermanii 26:895 Betula maximowicziana 26:895,899 Betula ovalifolia 26:899 Betula pendula 17:361,366 Betula platyphylla 17:361 Betula platyphylla var. japonica 26:255, 887,899 Betula platyphylla var. latifolia 26:895 Betula sp. 17:358.361;26:894,905 Betulaceae 17:358,359,364,366 Bhesa paniculata 23:652 Bicyrtes ventralis 5:223,224,253 Bidens aurea 25:614 Bidens campyltheca 29:682 Biemma sp. 25:703 Biflustra perfragilis 17:81,89,91;21:265; 28:619-620 2-methyl-6,7-di(methylthio)-2Hisoquinoline-3,5,8-trione from
1246
28:619 2-methyl-6-methylthio-2Hisoquinoline-3,5,8-trione from 28:619 Biflustra pregragilis 25:825 Bifurcaria bifurcata 18:713 Biomphalaria glabrata 7:432-435; 23:849,537;25:785 Biopholaria glabrata 25:792 Biota orientalis 25:275;29:102 Bipolaris sorokiniana 4:647;9:238; 21:196,199 Bipolaris zeicola 27:498 Bixa orellana 20:721,733,59 Blaberus discoidalis 9:488,489 Blaberus gigantus 22:381 Blastobacter sp. 25:841 Blastocladiella emersonii 5:276 Blastomyces dermatiditis 5:307;22:248 Blastomyces sp. 5:325,328 Blatta orientalis 9:488,489 Blatella germanica 6:53;9:488,489; 27:384 Bledius mandibularis 4:494 Bledius spectabilis 4:494 Bleekeria vitiensis 1:125 Blepharis edulis 27:188,191,193 Blepharispenum zangubaricum 25:251 Blighia welwitschii 15:205 Blumea malcomii 5:678 Bobolstemma paniculatum 21:665,674 Bocconia arborea 27:163,170 Bocconia cordata 26:488 Bocconia frutescens L. 27:163 Bocconia genus 27:162 Bocconia integrifolia 27:163 Bocconia pearcei 27:163 Bocconia sp. 27:155 Boerhavia diffusa L. 22:514;26:233 as anticonvulsive agent 22:514 liriodendrin from 26:233 Boerhavia repens L. 22:514 Boesenbergia 23:819 Boesenbergiapandurata 23:819; 29:775
Bohadschia argus bivittoside B,C from 7:270 Bohadschia bivittata 28:589 bivittosides A, B, C and D from 15:91
Bohadschia graffei 7:269 holothurins A,B from 7:269 holothurin A2 from 7:269 Bohadschia marmorata 7:270 bivittoside B,C from 7:270 Bohadschia tenuissima 7:270 bivittoside B,C from 7:270 Bohadschia vitensis 7:270 bivittoside B,C from 7:270 Bolabella auricularia 27:804 Bolbostemma paniculatum 7:143,144; 21:639 tubeimoside I from 21:645,665 Boletinus cavipes 20:26 Boletopsis grisea (Polyporus griseus) 29:277 Boletopsis leucomelaena 29:284 (Boletopsis leucomelas) 29:279 Boletopsis leucomelas 29:280 Boletus edulis 5:289 Bolinea lutea 22:249 Bombax malabaricum DC. 22:514 for epilepsy 22:514 Bombina variegata 23.'341 Bombyx mori 5:832;19:647;22:396; 23:661 ;26:991 ;29:6,10,25 Boophilus decoloratus 28:396,400 Boophilus microplus 25:706;28:398,402 essential oils from 28:398 Boophilus sp. 28:401,402 Bordeaux terpentine 29:83 Bordetella pertussis 25:521,538 Borrelia burgdorferi 21:646;26:695 Borreria capitata 11:278 borrecarpin from 11:278 Boswellia serrata 22:126,136 29:585, 586,691 Bothriochloa bladhi 11:278 eudesm-11-en-4-ols from 14:450 (+)-intermedeol from 14:450 neointermedeol from 14:450 Bothriochloa glabra 14:450 eudesm- 11-en-4-ols from 14:450 (+)-intermedeol from 14:450 neointermedeol from 14:450 Bothriochloa grasses 14:450,451 intermedeol from 14:450,451 neointermedeol from 14:450,451
1247
Bothriochloa insculpta 14:450,451 eudesm-ll-en-4-ols from 14:450 (+)-intermedeol from 14:450 neointermedeol from 14:450 Bothriochloa intermedia 14:449- 451 eudesm- 11-en-4-ols from 14:449-451 intermedeol from 14:450,451 neointermedeol from 14:450,451 Botrylus leactis 25:706 Botrylus schlosseri 25:719 Botryodiplodia malorum 25:143 BotJyospheria obtusa 25:318 BoOyotinia fuckeliana 12:400 Bot~ytis 4:246 Botlytis cinerae 5:598;26:418;21:196, 213,217;22:459,45;25:138,305,313, 314,316,662;26:404,405,508,553,555; 27:768 Botrytis fabae 2:434 Botzella sp. 25:790 Boussingaultia baselloides 21:666 12,20(29)-diene-30-noro leano lic acid from 21:666 Bouvardia ternifolia 24:306,309,319 bouvardins from 10:640 Bowlesia 27:661 Brabeium 26:1157 Brachyponera sennaarensis 5:224,225, 254 Brackenridgea zanguebarica 7:408; 23:342 Bradyrhizobium sp. 26:1154,1155 Bramia monnieri L. 22:513 for epilepsy 22:513 Brassica (SRK) 25:368,386 Brassica BN 29:618 Brassica campestris 26:187,481 Brassica compestris L. 19:246 Brassicajuncea 24:57,60 Brassica napus L. 18:495,498; 19:245 ;25:413 ;27:217 ;29:603,612,6 18 Brassica nigra L. 22:514;29:618 for epilepsy 22:514 Brassica oleraceae 26:748;29:603,612 Brassica rapa 28:425 Brassica sp. 23:756 Brassica TIBN 29:618
Bredius mandebularis 1:684 Bredius spectabilis 1:684 Brenania sp. 21:125 Brettanomyces anomalus 5:283 Brettanomyces bruxellensis 5:283 Brettanomyces dublinensis 5:283 Brettanomycesmyces lambicus 5:283 Brevibacterium ammoniagenes 20:32 Brevibacterium divaricatum 6:385 Brevicolyne brassicae 23:66 Briareum excavatum 25:670 Brickellia lemmonic 25:230 Brickellia veronicaefolia 5:680 Brosimopsis oblongifolia 28:203 Broussonetia genus 28:3 Broussonetia kazinoki 28:3-5 antifungal activity of 28:4 antiinflammatory activity of 28:4 antioxidant activity of 28:4 antispasmodic activity of 28:4 broussonetine C from 28:5 broussonetme D from 28:5 broussonetlne E from 28:5 broussonetlne F from 28:5 broussonetme G from 28:5 broussonetme H from 28:5 broussonetlne K from 28:5 broussonetlne L from 28:5 broussonetlne M from 28:5 broussonetme N from 28:5 broussonetlne O from 28:5 broussonetlne P from 28:5 broussonetme Q from 28:5 broussonetlnine A from 28:5 broussonetlnine B from 28:5 broussonol A from 28:6 broussonol B from 28:6 broussonol C from 28:6 broussonol D from 28:6 7,4'-dihydroxyflavan from 28:6 for increased vision 28:4 kazinol A from 28:6 kazinol D from 28:5 kazinol E from 28:6 kazinol K from 28:5 kazinol Q from 28:6 kazinol R from 28:6 sexual potency of 28:4
1248
Broussonetia papyrifera 27:834;28:3,4, 16,22;29:793 anti-cancer activity of 28:4 antifungal activity of 28:4 antioxidant activity of 28:4 diaphoretic activity of 28:4 in dyspepsia 28:4 in pregnancy 28:4 laxative activity of 28:4 Broussonetia zeylanica 28:3,4,28 aromatase inhibitory substance from 28:4 broussonetine from 28:28 cytotoxic flavonoids from 28:4 3,4 '-dihydroxy-2,3 '-b ipyridine from 28:28 8-hydroxyquinoline-4carbaldehyde from 28:28 8-hydroxyquinoline-4carbaldehyde oxime from 28:28 glycosidase inhibitory alkaloids from 28:4 Brucea antidysenterica 23:285 quassinoids from 7:374-376 Bruceajavanica 23:292;26:211 bruceoside-A from 7:371 bruceoside-B from 7:377 guaiacylglycerol-(-O-6'-(2methoxy) cinnamyl alcohol from 26:211 quassinoids from 7:377-379 Brucea sumatorana 7:391 Bruguiera conjugata 7:193,194 Bruguiera cylindrica 7:176,193,194 Bruguiera exaristata 7:191 Bruguiera gymorhiza 7:176,180-182,188, 195 Bruguiera parviflora 7:180,195 Bruguiera sexangula 7:176,191 Bruguiera sp. 7:176 Bryonia alba 20:13 Bryonia dioica 15:24;20:13;22:121; 27:14,25;29:614 bryoclulcoside from 27:14 bryonoside from 27:14 bryoside from 27:14 Bryum argenteum 2:277 Buchenavia capitata 21:132 Buchnera cruciata 22:514
Buddleja davaidii 20:644 buddlenol A from 20:644
Buddleja globosa 29:686 Buddleja madagascariensis 21:660 Bufo regularis 2:310,804;26:689 Bufobufo gargarizans 24:904-905 sterols from 24:904-905
Bugula dentata 17:88 Bugula neritina 5:394,395,153,75,77, 89,92,18:715,716,573-574,576; 21:252,316,317;25:726 bryostatin from 21:252 Bugula trubinata 17:102 Bugula turrita 17:80 Bugularia dissimilis 17:95,101 Bulgaria inquinans 26:450 Bulinus 7:426,432 Bulinus globosus 7:432,434 Bullera sp. 5:291 Bupalus piniarius 4:566 Buplerom falcium 24:146,148 Bupleurum bourgeaei 27:662 Bupleurum bourgeaei spp. 27:662 Bupleurum chinense 27:660 Bupleurum falcatum 21:665,688;25:474 saikosaponin from 21:665 Bupleurumfalcatum L. 27:660 Bupleurum fruticosum 17:117,127; 21:656; 27:693 Bupleurum genus 27:687 Bupleurum gibraltaricum 27:660,661 Bupleurum kaoi 27:660,693 Bupleurum marginatum 27:660 Bupleurum radix 21:651;25:474 saikosponins from 21:651 Bupleurum rigidum 27:659,662,663-665, 669,675,678,693 bioactive components of 27:659 biological activity of 27:688 roots of 27:665 structure of 27:662 Bupleurum rigidum L. subsp. Rigidum 27:659 Bupleurum rotundifolium 27:672 Bupleurum salicifolium 26:229 Bupleurum scorzonerifolium 25:474,476; 27:660,675 triterpene glycosides of 25:474
1249
Bupleurum sp. 21:671,686 from roots 27:686 saikosaponins from 21:671 Burasaia madagascariensis 26:1038 Burkholderia 26:582,605 Burkholderia caryophylli 26:594,599, 601,602,605 Burkholderia cepacia 26:605 Bursaphelenchus lignicolus 12:398; 26:429,435,493 Bursaphelenchus xylophylus 26:436,442, 466,470,471,474,485,487 Bursera ariensis 17:317 Bursera microphylla 17:330 Bursera permollis 26:216 deoxypodophyllotoxin from 26:216 (-peltatin methyl ether from 26:216 Bursera permollis 26:216-219 cholchicine from 26:216 4 '-de methoxy- 3 ',4 '-methylenedioxy-methyl rocaglate from 26:218 1-oxo-4 '- de methoxy- 3 ',4 '-methylenedioxyrocaglaol from 26:218 4'-episteganangin from 26:216 (-)-deoxypodophyllotoxin from 26:218 1-O-formyl-4'-methylenedioxymethyl-rocaglaol from 26:218 methyl rocagalate from 26:218 obavatifol from 26:219 obovaten from 26:219 obovatinal from 26:219 perseal A from 26:219 perseal B from 26:219 perseal C from 26:219 perseal D from 26:219 steganangin from 26:216 stegancin from 26:216 steganoate B from 26:216 steganolide A from 26:216 (-)-yatein from 26:218 Bursera schlechtendalii 18:556 Burseraceae 18:558;17:370 Butea frondosa 26:457 Butea monosperma (Lam.) 22:514 for epilepsy 22:514
Buxus alkaloids 2:175,205 Buxus papilosa 2:175 Byrsocarpus coccineus 26:69 Byrsonima crassifolia 24:779,826-835 pharmacological activity of 24:828 phytochemicals of 24:828-830 uses of 24:827,828 Cacachila 22:559 Cacaliahastata 19:149 Cacospongia linteiformis 25:698 Cadaba farinosa 9:64,65 sesquiterpenes from 9:64,65 Cadlina luteomarginata 9:6;21:318,334, 364 ;24:183,184 ;28:659 sesquiterpene isothiocyanate from 28:659 Caenorhabditis elegans 25:785;26:427, 429,432-434,437,439,441,447-449, 451,453,455,457,460-462,466, 468-471,473,474,481,487,488,490, 494,495,884;29:321; Caesalpina braziliensis 19:776 Caesalpinia bonduc L. 22:514 for convulsions 22:514 Caesalpinia echinata Lain. 27:37 Caesalpiniapulcherrima L. 20:475; 22:514,471;26:1142 for convulsions in children 22:514 Caesalpinia sappan 5:17 Caesalpinia vesicaria 26:1142 Caesalpinina digyna 23:520 Cailicogorgia granulosa 25:670 Calathrix WA 26:366 Calceolaria andina 28:408 Calderiella species 11:464 macrocyclic lipids from 11:464 Calea prunifolia 5:728 Calendula arvensis 17:126;21:665 oleanolic acid glycosides 21:665 Calendula officinalis 22:109,679;25:58 lutein from 7:361 Calliandra portoricensis 22:515 as anticonvulsant agent 22:515 Callinectes sapidus 19:647,672 Callipelta sp. 25:775;26:1210, 1211,1213,1175
1250
Calliphora erythrocephala 29:25 Calliphora victina 29:31 Callna vulgaris 29:691 Callosobruchus chinensis 21:379; 24:714,715 Callosobruchus maculatus 24:714 Callosobruclus analis 9:299 Cally~pongia johnstorii 25:717 Callyspongia sp. 25:724;28:673 Callyspongia truncata 25:723;28:712 Calocedrus decurrens 28:408 Caloglossa liprieurii 26:478 Calomyrmex sp. 5:223,224,230,253 Caloscypha fulgens 7:338 [3,~,-carotene from 7:338 Calpurina aurea 7:427;28:400 Calvularia virdis 25:704 Calycinum L. 22:656,672 Calycocystis Bunge 27:444 Calystegia sepium 22:718 Calyx nicaeensis 9:37,44 calysterol from 9:38 dihydrocalysterol from 9:37,44 (23R,24R)-Z3,24methylenecholesterol from 9:37 nicasterol from 9:37 Calyx podatypa 9:38,45;26:64,65 Camellia japonica 23:404,438 Camellia oleifera 23:406 Camellia sinensis 21:499;20:735; 23:341 ;25:472,478;29:579,582585,588,654,655 Camellia sinensis var. sinensis 21:660 Campnospermum auriculata 9:323 Camptotheca acuminata 23:405;24:269; 26:144 Campylotorpis hirtella 25:94 Canagana sinica 27:855 Canavalia gladiata 25:93;29:598 Canavalia lineata 29:598,603,604,607 Candida albicans 2:422,428,438-440, 292,5:323,324,342,356,369,282,400, 233 ;7:282;19:578;21:232,235,237, 608,611,662;20:712;22:57,61,74, 79,248,299,398,627,628;23:10,114, 123,164,235,335,347 ;25:258,759,764, 773,780,790,822;26:228,402,403,673, 1093,1124,1126,1134,1187,1203, 1216,1217;28:686;29:571,751
Candida aIbicans 1463D 28:476 Candida albicans ATCC 90028 28:476 Candida albicans ATCC 90029 28:476 Candida bogoriensis 5:294 Candida boidinii 22:601 Candida curvata 5:292 Candida cylindracea 12:337;18:429 Candida dubliniensis CBS 7987 28:476 Candida genus 29:328 Candida glabrata 22:57;26:1126 Candida guillermondii 2:422;22:57; 26:1 126 Candida humicola 5:292 Candida kefyr IFM 46921 28:476 Candida krusei 12:400;22:57;23:115 Candida lipolytica 5:292,308 Candida lusitaniae 5:283 Candida neoformans 22:57 Candida obtusas 5:283,292 Candida parapsilosis 5:292,323,324; 22:57;28:476 Candida patens 2:441 Candida pellicula 25:308 Candida pseudotropicalis 12:400 Candida rugosa 1:694,306 Candida sp. 5:291,292,328;21:192,232, 758;22:248;26.330,331,1087,1126, 1127,1134 Candida tropicalis 2:422,400;22:57 Candida tropicalis IFM 46816 28:476 Candida utilis 7:69,302,235;21:608,611 Candida valida 26:1091 Candidissimus 26:457 Candsburgia quercifolium 29:722 Canella winterana 2:447 Canna indica 28:425 Cannabis 7:7 Cannabis sativa 19:186; 22:515;25:532; 30:194,198 as analgesic 30:194 as intoxicant 19:186 as natural therapeutic herb 30:194 cannabinoids from 30:194 therapeutic use of 30:198 Canscora decussata 22:515 for epilepsy 22:515 Cantharellus cibarius 5:289;23:343 Cantharellus cinnabarinus 20:721 Cantharis vesicatoria 27:882
1251
Canthigaster solandri 21:364 Canthium bibracteatum 22:515 for convulsions in children 22:515 Canthium gueinzii 22:515 for epilepsy 22:515 Capnella imbricata 22:209 Agl~2)-capnellene from 13:34 capnellanes from 6:42 precapnelladiene from 6:33 Capparis baducca 22:515 Capparis decidua 9:73-75,77 alkaloids from 9:73-75,77 Capparis masaikai Levl. 27"18 mabinlin from 27:18 Capraria biflora 15:259 Capsicum annuum 13:320;20:586;29:610 Capsicum frutescens 20:135 Capsicum sp. 28:436,400;30:193 capsaicin from 7:93 Caralluma tuberculata 5:212;9:62-64 saponins from 5:212;9:62-64 Carapa abovaa 7:189 Carassius carassius 21:364 Carausius morosus 9:492 Carbonimidic dichlorides 21:346 Carcinus maenas 19:628;25:718 Cardamine pratensis L. 22:515 for epilepsy 22:515 Cardwellia sublimis 9:320 Carex kobomugi 26:530 Carex pumila 26:551 (-)-(-viniferin from 26:551 Caribbean gorgonian 29:103 Carica papaya 29:592,604 Carimbia subgenus 24:233 Carissa edulis 20:619 Carpesium divaricatum 29:89 Carpinus cordata 17:369 Carpinus species 17:369 Carpophilus hemipterus 29:282,292 Carthamus lanatus 14:450,451 eudesm-11-en-4-ols from 14:450 intermedeol from 14:450,451 Carthamus tinctorius 26:436 Carum carvi L. 22:515 as anticonvulsant agent 22:515 CaJyophyllus flos 29:590 Caryopteris clandonensis 4:612 Casalpinia sappan 24:275
Casearia sylvestris 24:280-282 Casimiroa edulis 22:515 for convulsions in children 22:516 Cassia corymbosa 26:1140 Cassia fistula 29:617 Cassia garrettiana 22:626;28:574 Cassia leptophylla 20:486,487 Cassia occidentalis L. 22:516,580,582 for convulsions in children 22:516 Cassia siamea 1:174,385 Cassia singueana 22:580 Cassia sophera L. 22:516 Cassia sp. 29:420 Cassia torosa 22:580,581 Cassine balae (Elaeodendron balae) 5:743,744,747;7:149,150 friedo-olenenes from 7:149,150 triterpene quinone methides from 7:149,150 Cassine glauca 23:652 Cassine transvaalensis 23:653 Cassinia uncata 24:122 Cassipourea gerrardii 7:192 Cassipourea gummiflura 7:192 Castanea crenata 19:246 Castanea sativa 29:592 effects on cathepsin B chymopapain ficin papain 29:592 effects on trypsin 29:592 from Castanea sativa chestnut Fagaceae seed 29:592 Castanea sp. 29:585 Castanospermine australe 27:514 australine from 10:567 Castanospermum austale 12:342,343; 24:917;27:255 (+)-6-epi-castanosperime from 12:342,343 Castela texana 23:299 Castela tortuosa 23:296 Castilleja tenuiflora 24:799,835,836; 25:713 iridoids of 24:835,836 Casuarian junghuhniana 17:371 Casuarianaceae 17:371 Catalpa ovata 29:733 Catha edulis 22:427,436;23:652,660
1252
Catharanthus roseus 19:246;22:9;24:774; 25:3 84 ;26:144 ;26:217,828,829,753; 27:744,780;27:780;27:780,782; alkaloid production 2:370-391 alkaloids of 7:416 catharanthine from 13:663;14:855 growth inhibitory activity of 7:416 leurosine from 14:860 vinblastine from 8:283;14:805 vincristine from 8:283;14:805 vindoline from 14:805;22:9 Catunaregam nilotica 21:660;22:516 for convulsions 22:516 for convulsions in childrens 22:516 Caulerpa racemosa 18:689,714 Caulerpalean algae 18:688 Caulocyctis cephalornithos 15:386 Caulophyllum thalictroides 27:277 Cayaponia tayuya 24:249 Cedecea lapagei 28:404 Cedrela tubiflora Bertoni 30:401 antiviral activity of 30:401 Cedronia granatensis 23:301 Cedrus deodara 8:415;28:402,416 Cedrus odollam 22:516 for epilepsy 22:516 Ceiba pentandra 29:708 Celastrus angulatus 18:771;23:654,666 antifeedant activity of 23:666 insecticidal activity of 23:666 Celastrus flagellaris 23:667 Celastrus gaumeri 30:691 in treatment of diarrhea 30:691 in treatment of snake bite 30:691 Celastrus gemmatus 23:667 Celastrus glaucophyllus 23:654 Celastrus hindsii 30:690 celasdin A from 30:690 celasdin B from 30:690 celasdin C from 30:690 maytenfolone-A from 30:690 Celastrus orbiculatus 29:88,91,708 Celastrus paniculata 5:743,744,747; 20:521 ;21:614;22:516;23:654 as antiepileptic 22:516 Celastrus pomonella 30:697 mortality of 30:697 Celastrus rosthornianus 23:667
Celastrus scandens 23:655;30:664 celastrol from 30:664 pristimerin from 30:664 Celastrus sp. 18:741,753;23:651 Celastrus stephanotifolius 23:672;30:646 lupane caffeoyl esters from 30:646 Cellaria pilosa 17:95,101 Cellaria species 17:89,92 Cellulomonas dehydrogenans decapenoxanthin from 7:69 Celosai argentea 25:476 Celtis cinnamomea 22:516 for convulsions 22:516 Celux pipens 19:481 Cenarchaeum symbiosum 25:718 Centaurea 29:580 Centaurea cyanus 22:679 Centella asiatica L. 21:674;22:516 asiaticoside from 21:674 Centipeda minima 26:808 Centipeda orbicularis 22:516 for epilepsy 22:516 Centrocerus clavulatum 26:478 Centrolobium paraense 17:367 Centrolobium robustum 17:367 Centrolobium sclerophyllum 17:367; 26:902 Centrolobium species 17:358,366 Centrolobium tomentosum 17:367 Cephaelis ipecacuanha 21:97;26:144,836 emetine from 21:97 Cephalodiscus gilchristi 18:875,876, 901,902 Cephalosporium acremonium 11:211, 6192;2:263 Cephalosporium aphidicola 21:721; 24:197;25:153,155 aphidicolin from 22:234 Cephalosporium caerulens 5:613 Cephalotaxus harrington var. drupacea 24:289,291 Cephalotaxus species 19:141 Cephalothrix linearis 18:725 Cerastoma brevicaudatum 28:651 (methylthio)furodysinin from 28:651 dithiofurodysinin disulfide from 28:651 Ceratiomyxa fruticulosa 29:237
1253
Ceratitis capitata 5:223 2,5-dimethyl-3-ethyl-pyrazines of 5:223 Ceratocistis fimbriata 23:355 Ceratocystis brunnea 5:306 Ceratocystis fimbrata 5:305,306,351 Ceratocystis minor 15:385 Ceratocystis paradoxa 5:306,307 Ceratocystis sp. 5:296,305,309,325; 26:1127 Ceratocystis stenocerus 5:305 Ceratocystis ulmi 5:305 Ceratocytis fimbriata 25:485 Ceratodictyon spongiosum 25:902;28:683 cis, cis-ceratospongamide of 28:683
trans, trans-ceratospongamide of 28:683
Ceratonia siliqua 21:504;26:1139,1142 Ceratosoma brevicaudatum 25:815 Ceratozamia spinosa 26:1158 Cerbera mangmas 7:176 Cerbera odollum 7:195;22:516 Cercidothrix Bunge 27:444 Cercis siliquastrum 26:1145 Cercospora beticola 15:351 ;22:459 Cercospora taiwanensis 15:383 Cereale secale 9:328 Cerebrotendinous xanthomatosis 17:207 Ceriops decentra 7:192 Ceriops sp. 7:176 Ceriops tagal 7:176,180,195 Cerotoma trifurcata 9:392 Ceterach officinarum 29:573,580 Cetraria islandica 5:309,310,322 Cetraria richardsonii 5:310,311 Ceveratrum group 23:563 Chaenorhabdtis 26:429 Chaetomella acutiseta 21:194 chaetomellic acid A from 21:194 chaetomellic acid B from 21:194 Chaetomium 5:730,203 Chaetomium cochiliodes 25:168,170 Chaetomium globosum 21:211,220,221, 229;28:125 2-(buta- 1,3-dienyl)-3-hydroxy4(penta- 1,3-dienyl) tetrahydrofurane from 21:211 Chaetomium sp. 21:220,221 ;27:382
Chamaceyparis pisifera 29:171 ;24:206 Chamaecaparis nootkatensis 23:341 ; 28:408
Chamaecyparis obtusa 25:246;28:234 Chamaecyparis pisifera Endle 29:170 Chamaecyparis sp. 21:615 Chamaesaracha conioides 22:28 Chamomila recutita 22:427 (-D-glycosyl-7-apigenine from 22:427 luteolin from 22:427 quercetin from 22:427 Chara globularis 18:677 charamin from 18:677 3-azelidinol from 18:677 4-azoniaspiro [3,3 ] heptane-2,6-dioi 18:677 Charania lampas 15:58,88 glycosidase of 7:286,288 Charonia sauliae 7:306,724 Chartella papyracea 17:85,86,89,92,692 Cheilantes 26:722 Cheimonophylum candidissimus 26:456, 457 Chelaner antarcticus 6:436,445 pyrrolidine venom alkaloids in 6:436 pyrrolizidine alkaloids in 6:445 Chelidonieae 27:161 Chelidonium majus 27:155,158,159, 162,168,169;29:592 Chelidonium majus L. 27:158 Chelynotus semperi 17:23;21:269;25:893; 28:639 Chenopodium album 7:398 Chenopodium ambrosioides 20:12;26:431 Chenopodium anthelminticum 20:12 Chenopodium botrys 21:584 Chenopodium quinoe 9:402 Chenopodium spp. 28:392 Chilo suppressalis 24:715;29:25,29 ajugasterone B activity in 29:28 makisterone D activity in 29:28 shidasterone (stachysterone D) activity in 29:28 2~,3j3,20R,22R,25-pentahydroxy14[3-methyl-5 ]3-cholest-7,12-dien6-one activity in 29:28 Chilomonas paramecium 2:294
1254
Chiloscyphus polyanthos 2:278,279; 18:609
Chlorophora tinctoria 22:360;29:582, 573,580,585
Chiloscyphus rivularis 20:472 Chironomus tentans 29:32 Chlamydia 26:1134 Chlamydia trachomatis 13:183 Chlamydomonas reinhardtii 26:364 Chlamys hastata 25:813;28:717 Chlonostachydiol 26:451 Chlonostachys cylindrospora 26:451 Chlorella 25:429;30:762,764,766,787
Chloropseudomonas ethylica 7:363 Chondodendron autumnale 25:476 Chondodendrum tomentosum 13:631 Chondostoreium purpureum 21:196 Chondria armata 17:21;26:479 Chondria baileyana 26:479 Chondria californica 25:842 Chondria oppositiclada 6:40
detoxicating enzyme activity of 30:766 hypotensive components in 30:787 uses of 30:762 Chlorella cell 30:783,765 GABA in 30:784 glutamic acid in 30:783 Chlorella diet 30:763 effects of 30:763 on fecal excretion 30:763 Chlorella effect 30:787 on plasma rennin activity 30:787 Chlorella emersonii 26:358 Chlorella kessleri 25:430 Chlorella protothecoides 30:766 role in detoxication 30:766 Chlorella vulgaris 25:430,431,450,452, 453 ;26:358,372;30:761,762,766,782 against microbial infection 30:782 antitumor activity of 25:452 effect on gluthathione S-transferase 30:765 effect on skin papillomas 30:762 effects on fecal excretion 30:762 host defensive study of 30:761 immunological effect of 30:782 mechanism of 30:782 pharmacological study of 30:761 role in dioxin excretion 30:762 role on inhibition of cytochrome P-450 30:766 role on inhibition of malondialdehyde levels 30:766 topical application of 30:762 use in colorectal carcinomas 30:762 Chlorella vulgaris strain CK 22 (CVs) 25:429-433,436,437,440,447,450
Chondria sp. 26:488 Chondria tenuissima 25:249 Chondrilla sp. 18:718 Chondrococcus hornemanni 5:343 Chondromyces sp. 25:730 Chondrosia collectrix 18:719 Chonistoneura fumiferana 26:876 Chorda 26:1121 Choriaster granulatus 7:299 Chorisia speciosa 26:1157 Choristoneura fumiferana 22:388 Chromatogaster scutellaris 6:455-458 Chromis chromis 21:364 Chromobacteria 21:298 Chromodoris cavae 9:4,13 Chromodoris elisabethina 28:650
cycloeudesmol from 6:40
icthyotoxic latrunculin A from 28:650 Chromodoris funarea 17:9,10 Chromodoris lachii 17:13 Chromodoris macfarlandi 17:11 Chromodoris maridadilus 6:69 Chromodoris norrisi 17:12 Chromodoris species 17:12,14 Chromodris hamitoni 25:735
Chrysanthemum mortifolium 22:122;29:586-588 effects on CHY 29:586
Chrysanthemum cinerarifolium 28:384 pesticide properties of 28:383 secondary metabolites from 28:384 Chrysanthemum frutescens 9:317 Chrysanthemum golden 20:246 Chrysanthemum parthenium 27:376 Chrysanthemum sp. 7:427 Chrysanthenum coronarium 25:944 Chrysocephalum ambiguum 25:251
1255
Chlysochromulina species 6:135 Chrysomma sinensis 5:837 hemoglobin components of 5:837 Chrysoplenium pseudofauriei 5:678 Chrysosplenium americanum 5:682 Chrysosplenium flagelliferum 5:682 Chrysosplenium grayanum 5:682 Chukrasia tabularis 9:105 Chymacyparis taiwanesis 29:698 Chytridiomycota 22:246 Cicer arietinum 18:719;26:1268,1288 Cicer arietium 25:93 Cimicifuga 25:180;29:582 Cimicifuga dahurica 22:516 Cimicifuga racemosa 27:277 CimoCuga sp. 27:395 Cinachyra sp. 19:581 Cinachyrella alloclada sp. 26:67 Cinchona 21:488 26:835,836 Cinchona ledgeriana 26."144 Cinchona officinalis 25:476 Cinchona robusta 30:344 suspension culture of 30:344 Cinchona spp. 22:146;516 Cinchona succirubu 26:780,820 Cinnamomm osmophloeum 15:29 Cinnamomum camphora 22:516;25:140, 156;26:1039;28:419 as anticonvulsant 22:516 for hysteria 22:516 for epilepsy 22:516 Cinnamomum cassia 22:427 epicatechol from 22:427 epicatechol-O-glucoside from 22:427 Cinnamomumjaponicum 28:419 Cinnamomum osmopholeum 27:16 trans-cinnamaldehyde from 27:16 Cinnamomum philippinense 26:240,249 cinnamophilin from 26:240,249 meso-dihydroguaiaretic acid from 26:240 Cinnamomum sieboldii Meisner 15:33; 27:18,35 Cinnamtannin B-1 from 27:18,35 Cinnamtannin D-1 from 27:18,35 Cinnamomum sp. 24:275;29:588 Cinnamonium camphola 18:558 (-)-dimethylmatairesinol 18:558
Cinnamonum camphora 21:621;27:377 Cinnamonum zeylanicum 27:377 Ciocalypta sp. 21:349,355 Cioclapta species 17:16 Ciona intestinalis 5:405,408,249 Ciona savignyi 25:784 Cirsium japonicum 26:436 Cissampelos pareira 29:578 Cissua integrifolia 22:517 for epilepsy 22:517 Cistanche deserticola 25:468,476 Cistrus hirusutum 19:246 Cistus clusii 25:250 Cistus creticus 25:246,249, 250,252,255,256,257,266 Cistus creticus sub sp. erioocephatus essential oils of 25:259 Cistus incanas sub sp. creticus 25:258, 266 Cistus ladaniferus 25:252 Cistus laurifolius 25:250 Cistus palinhae 25:250 Cistus spp. 29:581 Cistus symphylifolius 25:250 essential oils 25:255 Citeromyces matritensis 5:283 Citeromyces sp. 5:280 Citrobacter freundii 26:402 Citrullus colocynthis 5:750;20:1322:517 as antiepileptic agent 22:517 Citrullus vulgaris 29:614 Citrus buxifolia 13:350 atalfoline from 13:350 Citrus auranhtium ssp. amara 27:372375,377 petitgrain oil from 27:372-375,377 Citrus aurantium 15:5;22:517~25:476; 27:17,377;29:573 neohesperidin dihydrochalcone from 27:17 Citrus decumana L. 13:348,349;22:517 Citrus depressa 13:348 citracridones I,II from 13:348 citpressine I from 13:348 Citrus genus 27:377 Citrus grandis 13:348,349;22:517 baiyumine A from 13:348,349 baiyumine B from 13:350 butanine from 13:350
1256 citpressin II from 13:350 grandisines I,II from 13:350 grandisinine from 13:350 honyumine from 13:348,349 prenyl-citpressine from 13:350 Citrusjunos 13:348,349 junosidine from 13:348,349 Citrus latifolia 27:372,377 Citrus limon 23:747;25:594;27:375,377 Citrus maxima 22:517 for epilepsy 22:517 for convulsive cough 22:517 Citrus natsudaidai 13:350;27:17,375 natsucitrines I,II from 13:350 Citrus paradisi 14:450;23:747 eudesm-11-en-4-ols from 14:450 (+)-intermedeol from 14:450 naringin dihydrochalcone from 27:17 Citrus reticulata 23:747;27:375;29:573 Citrus sinensis 13:348,350;23:747;27:375 citbrasine from 13:350 citrusinines I,II from 13:348,350 Citrus sp. 5:651 ;25:128,266,267 Citrus unshiu 18:682 Cladobotryum rubrobrunnescens (Hyphomycetes) 26:449 Cladobotryum varium 26:449 Cladonia alpestris 5:310,313 Cladonia confusa 5:310,313 Cladonia crispata 5:310 Cladonia mitis 5:310 Cladonia rangiferina 5:310 Cladonia sp. 5:310 Cladonia squamosa 5:310 Cladophora fascicularis 5:367 Cladosporiam cladosporiodes 22:627 Cladosporin cladosporiodes 11:193; 15:386,193 ;23:343,535 ;26:553; Cladosporium coccodes 25:305 Cladosporium colocasiae 26:1091,1093 Cladosporium cucumerinum 7:406,409, 411,413;15:64,415,421,433,64;21:189 ,257,266,275,277,281,283,284,662; 23:347 ;25:776;26:333,673 Cladosporium fulvum 25:302,308,398, 399,400 Cladosporium herbarum 20:245;2:475; 5:302
Cladosporium phlei 21:189 Cladosporium sp. 5:301,325,328,370; 25:145;26:1128 Cladosporium sphaerospermum 26:228 Cladosporium suaveolens 13:309-311, 313,315 Clado~porium wemeckii 5:301 Cladosporum herbanum 7:119 Cladrastis lutea 5:678,683 Clatha palustris 7:427 Clathria pyramida 6:351;28:715 Clathria sp. 28:702 Clathrina clathrus 25:870 Clausena anisata 22:517 as anticonvulsant 22:517 Clausena anista 22:517 Clausena harmandiana 9:400 Clausena heptaphylla 2:118 Clausena indica 2:118 Clausena pentaphylla 2:118 Clavelina cylindrica 25:859,793;28:644 cylindricine F from 28:644 genistic acid 28:259 Clavelina lepadiformis 29:426 Clavelina picta 10:249;29:426 Claviceps 21:91,488 Claviceps eurotium 9:203 Claviceps fusiformis 5:278 Claviceps purpurea 13:631 Claviceps sp. 5:278;11:200 Clavicipitales 9:203 Clavularia inflata 6:77 (+)- 12-acetoxysinularene from 6:77 Cleislopholis staudtii 22:400 Cleistanthus collinus 26:204 cleistanthin A&B from 26:204 Cleistopholis patens 2:340;22:400; 23:4,341 Clematis hexapetala 19:125 Clematis sinensis 20:539,540 Cleome cileata 22:517 Cleome icosandra 18:28;23:487 Cleome viscosa 18:28 Clerodendron inerme 20:539,540 Clerodendron wildii 21:662 Clerodendrum uncinatum 7:408,417,423; 23:343 Cliona celata 5:411
1257
Cliona chilensis 25:778 Clitocybe acromelalga 19:163;26:479 Clitocybe geotropa 18:813,814 Clitocybe nebularis 18:813,814 Clitocybe subilludens ( Omphalotus subilludens) 29:296 Clivia miniata 20:351 ;26:619,620 Clostridium 13:303 Clostridium difficile 5:601 Clostridium formicoaceticum 20:821,824, 861-862,867,869,870,871,873-879, 881 Clostridium kluyveri 20:821,824,831,834 Clostridium perfringens 5:601,71,81,86, 87,16:108;25:925 Clostridium tetanomorphim 9:598,601; 20:821,824,861-863,867,869,870,871 Clostridium tyrobutyricum 20:821,824, 829,830,834-839,863,873-877 ;25:147 Clusia nemorosa 22:659 Clusia plukenetii 22:660 Clusia portlandiana 22:659 Clusia rosea 22:659 Cnemidocarpa bicornuta 25:765 Cnestis ferruginea 22:517 Cnidaria 21:3,272 Coccidioides immitis 22:57 Cocculus sermentosus 22:517 for epilepsy 22:517 for nocturnal epilepsy 22:517 Cocculus spp. 3:456,478 Cocculus trilobus 3:488 Cochliobolus lunatus 25:318 Cochliobolus miyabeanus 23:133;26:460 Cochlodinium polykrikoides 30:400,408 anti-influenza activity of 30:408 Codium arabium 25:704 Codium dworkense 25:725 Codium latum 26:1138 Coelenterata 21:272 Coffea arabica 29:578 Coffea sp. 21:502 Coix lachryma 27:193,212;29:599 Colaphellus loweringi 18:771 Colaptes auantus 5:836 Colchicum autumnale 5:46;25:473; 29:356,358 hepatoprotective effect 25:472 serum ALT activity 25.'473
Colchicum kesselringii 29:356 Colchicum luteum 22:517 for epilepsy 22:517 Colchicum ritchii 29:358 Colebrookea oppositifolia 22:517 for epilepsy 22:517 Coleoptera 22:371 Coleus amboinicus 22:517 Coleus aromaticus 22:517 for convulsive affections 22:517 for epileptic affections 22:517 Coleus forskohlii 19:137;25:252, 256,261,958 forskoline from 13:659 Coleus sativus 25:956 Coleus sp. 7:96,118 Collectotrichum coccodes 25:307 Collectotrichum lagenarium 16:302 Colletotrichum dematium 9:230,238,239 Colletotrichum gloeosporiodes sp. jussiaea 9:288,229,231-235,238-241 Colletotrichum gloeosporioides (Glomerella cingulaa)9:228, 230,232,238-240 Colletotrichum gloeosporioides sp. aeschynomene 9:230,238,239 Colletotrichum graminicola 9:230, 238,239 Colletotrichum heterostrophus 22:267 Colletotrichum lagenarium 12:400; 22:266 Colletotrichum lindemuthianum 9:230, 239 Colletotrichum malvalum 9:230,231, 238,239 Colletotrichum species 9:228,230, 239,247 Collisella limatula 17:26 Colocynthis vulgris 5:743,744,750 Colubrina asiatica 21:673 jujubogenin-3- O-glycosides from 21:673 Comantheria briareus 7:266 Comantheria perplexa 7:266;28:719 polyketide sulfates of 7:266 Comanthula pectinata 7:266 polyketide sulfates of 7:266 Comanthus parvicirrus 7:266
1258
Comatula pectinata 28:719 anthraquinones from 28:719 Combretaceae 25:180 Combretum 25:180,183;26:1157 Combretum glutinosum 28:424 Combretum micranthum 28:424 Commiphora incisa 22:117 Commiphora molmol 24:119 Commiphora mukul 5:695,700,701 Compylotropis hirtella 25:93 Conangium odoratum 24:275 Condylomata acuminata 26:151 Coniothyrium minitans 21:207 Coniothyrium palmarum 21:207 Coniothyrium spp. 21:207 Conium maculatum L. 22:517;25:528 for epilepsy 22:517 Conocephalum conicum 2:273,277, 278;9:249 Conopeum seuratum 17:79 Conservula cinisigna 26:698 Consolida 26:868 Consolida orientalis 27:188,191 Conthium guiinzii 22:515 Conus 25:732 Conus radiatus 21:320 Convolvulus arvensis L. 15:341 ;22:518 Convolvulus pluricaulis 22:518 Convorvolus microphyllus 13:312 Conyza dioscoridis 28:425 Conyza filaginoides 29:586
Conyza odentophylla (Pluchea arguta) sesquiterpenes from 9:65-68
Conyza steudellii 25:25 Conyza trihecatactis 25:252 Cooperia curticei 26:490 Copaifera L. 25:168 Copaifera riticulata 22:360 Coprinus mcrorhizus var. microsporus 5:288
Copsychus saularis 5:837 hemoglobin components of 5:837
Coptisjaponica var. dissecta 26:268 Cora islandica 5:313 Cora pavonia 5:313 Cora silandica 5:128 synthesis of 5:128
Coracias benghulensis 5:837 hemoglobin components of 5:837
Coracina novachollandiae 5:837 hemoglobin components of 5:837
Corallistes fulvodesmus 25:829;26:1213; 28:688
Corallistes sp. 26:1214 Corallistes undulatus 26:1214 Corbicula sandai 26:1123 Corchorus acutangulus 18:650; 23:487,511 23-hydroxylongispinogenin from 18:650 313,1613,23,28-tetrahydroxyolean12-ene from 18:650 saponins of 23:511 Corculigo 25:180 Cordia goetzei 7:408,409;23:342 Cordiceps ophioglossoides 5:279,318,320 Cordiceps sinensis 5:279 Cordoa piaca 29:777 Cordyceps cicadea 23:115,134 Cordyceps ophioglossoides 23:133 Coreopsis parvifolia 5:800 Coriandrum sativum 27:376 Coriariajaponica 23:404 Coriaria nepalensis 13:311 Corilous versicolor 452 Coriolus sanguineus 26:1012 Cornitermes ovatus 15:384 Cornitermes pugnax 15:384 Cornus florida 7:427 Cornus officinalis 23:405 Corona virus 5:360 Coronilla 27:519 Coronopifolia 25:771 Corpora allata 22:377 Corpora cardiaca 2:90,93,94,99,106,
112;9:487,490 Cortex eucommia 20:646 Corticium caeruleum 18:712 Corticium rolfsii 21:196 Corticum sp. 25:707 Cortinarius odorifer 22:580 Cortinarius sp. 22:556,579 Corvularia eragrostidis 29:475 Corvus splendens 5:837 Corydalis caucasica DC. 27:163 Corydalis decumbens 21:733 Corydalis flabellata 27:169 Corydalis rutifolia 27:170
1259
Corydalis severtzowii RgI. 27:163 Corydalis sp. 22:518 Corylus 26:894,905 Corymbellus aureus 6:135 Corymbiu villosum 25:251 Corynanthejohimbe K. 26:143 Coryne cassiicola 25:149 Corynebacteirum kutschei 25:452 Corynebacteirum sp. 25:145 Corynebacterium bovis 12:400 Corynebacterium fescians 26:618 Colynebacterium glutammicum 13:320 Corynebacterium parvum 23:134 Corynebacterium poinsettiae 7:357; 20:594 Corynespora cassiicola 25:149,162,166 Corythuca 26:443 Cosciansterias tenuispina 7:298 cosicinasteroside D from 7:298 Coscinasterias tenuispina 15:46,51,52 Coscinoderma mathewsi 25:699;28:672 Coscinoderma sp. 28:670 Costaricensis 26:484 Costasiella ocellifera 25:787 Costaticella hasta harman from 18:726 pavettine from 18:726 Costaticella hastata 17:90 Costaticella hastata 21:260 Costus speciosus 23:821 Cotoneuster lactea 23:341 Coumarouna odorata 23:337 Cowania mexicana 24:249 Cowdria ruminantium 28:394 for rickettsial pathogens 28:394 Coxiella burnetii 28:394 in cattle 28:394 in sheep 28:394 Crataegus monogyna 21:502;22:118; 29:579 Crataegus pinnatifida 27:861 ;29:588 Crataegus sinaica 21:507 Crataegus sp. 21:535 Crataeva nurvala 5:209 Creila spinulata 25:832 Crella sp. 25:704;28:706,707 crellastanin A from 28:706 crellastatins B-M from 28:707
Crella spinulata 28:708 benzylthiocrellidone from 28:708 dimedone unit of 28:708 Crematogaster deformis 15:383 Crematogaster lineolata 6:454 Crematogaster scutellaris 6:422,453,455 Crescentia cujeta 20:494 furanoaphthoquinones from 20:494 Cribicellina cribraria 25:819 Cribochalina sp. 25:900 Cribraria intricata 29:256 fruit bodies of 29:256 Cribraria purpurea 29:258 antimicrobial activity of 29:258 crude extract of 29:258 Cribricellina cribraria 17:79,89-90; 21:260;28:619 [3-carboline alkaloid from 28:619 carboline from 28:619 1-ethyl-4-methyl-sulfone- [3antimicrobial activity of 28:619 Cribrocalina vasculum 9:37 dihydrocalysterol from 9:37 petrosterol from 9:37 Crinum americanum 26:616 Crinum asiaticum 18:687 Crinum oliganthum 20:234 mesembrenol from 20:234 Criptococcus neoformans ATCC 90112 28:476 Cristaria plicata 25:868 Crithidia deanei 2:296-298 polysaccharides in 2:296-298 Crithidia fasciculata 2:295-297,577 Crithidia guilhermei 18:791,792 Crithidia harmosa 2:298 Crithidia luciliae 2:298,791,792 Critonia quadrangularis 24:103 Crocus sativus L. 22:518;26:293,294, 296,302,303,304,306,307;28:313,314,3 15 anti-tumor activity of 28:314,315 as coloring agent 28:313 ethanol extract of 28:315 effect on central nervous system 28:315 for flavoring 28:313
1260
for sedative in convulsions 22:518 uses in medicine 28:313 Crocus sp. 26:297,299 carotenoids from 26:297,299 derivatives of 26:299 Croomiajaponica 21:759 Crossandra pungens 27:191 Crossaster papposa 7:298,299;15:61,69 Crossopetalum gaumeri 30:660,662 cytotoxic cardenolide from 30:660,662 Crossopteryx febrifuga 7:417,425 Crossostephium chinese L. 22:518 for infantile convulsions 22:518 Crosus saliva L. 25:955,956 Crotalaria albida 25:93 Crotalaria madurensis 23:341;29:771 Crotalaria species 19:499 Croton cajucara 29:100 Croton genera 9:265;27:830 Croton lacciferus 23:341 Croton lechleri 22:361 Croton macrostachys 4:612 Croton tiglium 12:233;20:19;25:242 Croton zedoaria 29:90 Crypthecodinium cohnii 9:47 Cryptocarya caloneura 19:481 Cryptocarya pleurosperma 1:365 Cryptococcus albicans 21:758 Cryptococcus albidus 5:292,328; 8:336,352 4-thioxylobiose from 8:336,352 Cryptococcus dimennae 26:618 Cryptococcus fagisuga 25:662 Cryptococcus flavescens 5:294 Cryptococcus laurentii 5:292,294,328 Cryptococcus magnus 26:618 Cryptococcus neoformans 2:428,446, 292,322,5:326-328,400,408 ;21:758; 22:57;248,299;23:8,10,136,242,481; 26:228,1127 Cryptococcus sp. 5:291,292,294,328; 21:192;22:248 Cryptococcus terreus 26:618 Cryptolepine 5:751,752 Cryptolepis sanguinolenta 5:751;26:828, 1060 cryptolepine from 26:828 Cryptolestes ferrugineus 8:227;19:154
Cryptomeriajaponica 2:402;19:246; 25:257,275;29:101 Cryptoporus volvatus 29:87 Cryptothetia crypta 21:252;25:712 spongouridine from 21"252 spongothymidine from 21"252 Cualzorra 22:559 Cubitermes 8:230;21:277 defence secretion of 8:220 Cubitermes umbratus 8:230 cubitene from 8:230 Cuculus micropterus 5:837 hemoglobin components of 5"837 Cucumaria echinata 15:94;28:596,720 neuritogenic activity of 28:720 Cucumaria fraudatrix 15" 87,92 cucumariosides GI, CI and Cz from 15:87,92 Cucumaria frondosa 7:277;28:720 2,6-dimethylnonane- 1-sodium sulfate from 28:720 frondogenin from 7"277 2,4,6-trimethyl-nonane- 1-sodium sulfate from 28:720 Cucumariajaponica 7:275;15:87;28:595 cucumarioside-A0-3 from 28:595 cucumarioside-A~-2 from 28:595 cucumarioside-A2-1 from 28:595 cucumarioside-A2-2 from 7:275; 15:87 28:595 cucumarioside-A3 from 28:595 cucumarioside-A4-2 from 28'595 cucumarioside-A6-2 from 28:595 cucumarioside-AT-1 from 28:595 cucumarioside-A7-2 from 28:595 Cucumaria koraiensis 28:599 Cucumaria lefevrei 15:92;28:596 from lefevreioside A~ from 28:596 from lefevreioside A2 from 28:596 from lefevreioside B from 28"596 from lefevreioside C from 28:596 Cucumis CMCTI-I 29:614 Cucumis CMeTI-A 29"614 Cucumis colocynthis L. 22"518 for epilepsy 22:518 Cucumis melo 25:390;29:614 Cucumis sativus 29:614
1261
Cucumis sp. L. 22:518
Cuscuta europea L. 22:518
for epilepsy 22"518 Cucurbita maxima 29:614 Cucurbita pepo 29:615 Cucurbita sp. 29:590
Cuscuta reflexa 25:944,945;29:573 Cussonia barteri 7:427;21:673
Cudrania cochinchinenesis 28:203 Cudrania tricuspidata 28:203 Culcia novaeguinea 7:298,15:69 Culex pipiens fatigans 3:157 Culex pipiens pallens 21:252 Cuminum 29:579 Cuminum cyminum 28:427 Cunninghamella 25' 172 Cunninghamella blakesleana 23:22,42; 25"172,173
Cunninghamella echinulata 20:792 Cunninghamella elegans 20:214 Cunninghamia lanceolata 25:251 ;29:101 Cupressaceae 21:615
Cupressus sempervirens 25:253 Curculigo latifolia Curculigo latifolia Dryand. 15:36; 27:18,39 curculin from 27:18,39 Curculigo orchioides 25:227 Curculigo orchioidis 21"651 Curcuma 23"825 Curcuma aromatica 22:518;24:269; 27:852;29:577 for convulsions 22"518 Curcuma comosa 26:883 Curcuma longa 8:52,13:660,17:363, 373,377,379,20: 734 ;21:616;24:272, 274;25",469,476;26:457,474,882,887;2 7:852;29:695 curcumin from 26:887 hepatoprotective activity 25:469 serum transaminase activity 25:469 Curcuma phaeocaulis 24"274 Curcuma species 17:358;26:905 Curcuma tinctoria 17:357 Curcuma xanthorrhiza 17:364;23"836; 24:274,288;6:883,884;27:852;29:87 Curcuma zedoaria 24:272;25" 172;29:87 Curtobacterium pusillum 23:92 Curvularia lunata 9:412,417,418;4:76 25:254,261,260,263;26:227 Curylus heterophylla 23"403
for fits 22:518
oleanolic acid glycoside from 21:673 Cussonia spicata 7:427,435 Cusumis sativa 24:57,60 Cutleria multifida 21:306 Cyamopsis tetragonolobus 26:1139 Cyathus sp. 24:942 cyathanes from 24:942 Cybister tripunctatus 5:700 Cycas cricinalis 25:529 Cycas revoluta 29:578 Cyclea atjehensis 20:552 Cyclea barbata 20:522 Cyclocarya paliurus 27:15,28 cyclocarioside A from 27:15 cyclocarioside I from 27:15 Cycnomorium songaricum 29:574 Cyerce cristallina 21:317 Cylindrocarpon olidum 26:471 Cylindrocarpon sp. 27:871 Cylindrocladium ilicicola 21:215 ilicicolin-H from 21:215 Cylindrospermopsis raciborskii 25:732; 26:352 Cymbastela coralliophila 25:704 Cymbastela hooperi 25:689,814,856; 28:665 Cymbastela sp. 25:714,768,792,847 Cymbopogan winterianus 21:595 Cymbopogon citratus 28:398 essential oils from 28:398 Cymbopogon flexuosus 14:450,451 eudesm-11-en-4-ols from 14:450 intermedeol from 14:450,451 Cymbopogon nardus 28:398 essential oils from 28:398 Cynanchum decipiens 22:518 Cynanchum otophyllum 22:518 Cynanchum saccatum 22:518 Cynara scholaris 13:660 Cynara scolymus 23:752;25:943 Cynodon dactylon L. Pers. 22:518 for epilepsy and hysteria 22:518 Cynomorium songaricum 29:575 Cyperaceae spp. 27:766
1262
Cyperus aromaticus 22:399,400 Cyperus esculentus L. 22:518 for epilepsy 22:518 Cyperus iria L. 22:399 Cyperus monophyllus 22:400 Cyperus pilosus 22:400 Cyperus rotundus L. 22:401,518;24:272 for epilepsy 22:518 Cyperus serotinus 22:400 Cyprinus carpi 27:439;28:564 antitumor activity of 28:564 as diuretic 28:564 for eye fatigue 28:564 Cystobacter fuscus 28:144 Cystodytes dellechiajei 10:250 Cystodytes sp. 21:269;25:820;28:638 dehydrokuanoniamine B from 28:638 shermilamine C from 28:638 Cystodytes violatinctus 25:820;28:639 Cystophora torulosa 9:322 Cystoseira 26:1121 Cystoseira balaerica 20:35 Cystoseira crinita 20:25,28,35 Cystoseira elegans 18:712,713 Cystoseira spinosa (var. squarrosa) 9:321 Cytisus scoparius 15:525 (-)-3,13c~-dihydroxylupanine from 15:525 Cytoseria unsenoides 22:519 Cyttaria harioti 5:278;23:127 Dacrydium cuprassinum 3:117;13:19-22 Dacrydium intermedium 20:619 Dactylicapnos torulosa 27:177 Dactylopius coccus 20:734 Dactylospongia elegans 25:694 Dactylosporangium ATCC 53693 29:315 Dacus cucumis 5:225 2,5-dimethyl-3-,6-dimetyl pyrazines of 5:225 Dacus cucurbitae 5:225 2,5-dimethyl-3-methylpyrazines of 5:225 methylpyrazines of 5:222
Dacus dorsalis 5:222 2,5-dimethyl-3-methylpyrazines of 5:222 Dacus occfipitalis 5:222,223 2,5-dimethyl-3-ethylpyrazines of 5:222,223 Dacus oleae 4:571,222;14:521,19:131 Dahlia spp. 29:580 Dakaira subovoidea 25:831 ;28:620 6H-anthra[ 1,9-bc]thiophene derivatives 28:620 Dalbergia hupeana 25:93 Dalbergia parviflora 25:162 Dalbergia stipulacea 29:772 Daldinia concentrica 26:470 Dalea filiciformis 29:581 Daliocarpus dentatus 26:229 (-)-liriorinol B from 26:229 (+)-medioresinol from 26:229 (+)-pinoresinol from 26:229 Damacus carota 25:377,669 Damaliscus dorcas 19:122 Danaus gilippus 8:223 danaidone from 8:223 Danaus plexippus 21:107 Daphna genkwa 13:660 yuanhuacine from 13:660 Daphne cannabina 27:833 Daphne mezereum 20:22;27:833 Daphne odorata 26:465 Dasytricha 2:294 Datisca cannabina 5:678,682 Datura aurea 22:742 Datura brugmansia 22:734 Datura candida 22:742 Daturafastuosa L. 22:519,742 for epilepsy 22:519 Datura innoxia 11:204;22:742 Datura metel L. 22:519 for epilepsy 22:519 Datura. 17:395;21:104,488 Datura stramonium 20:135;22:742 Datura tatura 20:194 daturataturin A and B from 20:194 Daucus 29:579 Daucus carota W. 5:721,730; 22:519;27:686;29:592 as anticonvulsant agent 22:519 for epilepsy 22:519
1263
Daucus spp. 27:686 Davidsonia pruriens 29:588 Debalyomyces castelli 5:283 Debaryomyces hansenii 5:282,283 Debaryomyces kloeckeri 5:283 Debaryomyces phaffi 5:283 Debaryomyces subglobosus 5:283 Debregeasia saliciJblia 29:588 Deinbollia borbonica 22:519 for convulsions 22:519 for epilepsy and convulsions 22:519 Delesseria sanguinea 4:712 Delonix regia 29:604 Delphinium 20:19;26:868,869,871 Delphinium cardiopetalum 26:868 Delphinium consolida 22:519 Delphinium denudatum Wall 22:519 for epilepsy 22:519 Demodex genus 28:410 Dendrilla cactos 23:246 Dendrobaena clujensis 30:828 from Lumbricidae family 30:828 Dendrobates auratus 27:243 Dendrobates histrionicus 11:294 (+)-indolizidine from 11:294 Dendrobates pumilio 12:294;19:4; 27:242;29:439 panamanian population of 19:4 pumiliotoxin B from 12:294 Dendrobates speciosus 11:266;12:294 indolizidines from 11:266 N-oxides of allopumiliotoxin 267 A from 12:294 N-oxides of pumiliotoxin 323 A from 12:294 Dendrobates tricolor 12:294 pumiliotoxin 251 D from 12:294 Dendrobium crepidatum crepidamine from 12:285 crepidine from 12:285 dendrocrepine from 12:285 Dendrocotonus brevicomis 11:413 exo-brevicomin from 11:413 Dendroctonus pseudotsugae 22:388 Dendrodoa grossularia 5:412;10:245; 23:257,260;28:633 dendrodoine from 28:633 Dendrodoris grandiflora 17:28
Dendrodoris limbata 17:28 Dendropanax trifidus 2:98-103 dendropanoxide from 2:98-103 Dendrostilbella 21:233 Dendryphiella salina 10:152 Dendryphion sp. 27:871 Dennstaedtia hirsutu 26:111 Dennstaedtia scabra 26:722 Dentroctonus brevicomin 19:126 Dercitin sp. 28:686 antitumor activity of 28:686 antiviral activity of 28:686 immunomodulatory properties of 28:686 violet acridine alkaloid from 28:686 Dercitus 25:893 Dermasterias imbricata 2,4-di-O-methyl-[3-Dquinovopyranosyl-( 1>>2)-5O- sulphate-[3-D-fuco furanosyl from 15:66 imbricatine from 7:306 Dermasterias imbricate 25:824 Dermatophagoides farinae 28:417 Dermatophagoides pteronyssinus 28:417430 Dermatophilus congolensis 28:394 skin infection of cattle by 28:394 Dermocibes sp. 22:556,579 Derris 26:487;27:844 Derris araripensis 7:177,193 Derris laxiflora 29:785 Derris nicou 7:177,193 Derris scandens 27:844 Derris sericea 7:177,193 Derris trifoliata 7:176-178 Derris ulignosa 7:181,182 Derris urucu 7:177,193 Desmarestia menziesii 26:471 Desmia sp. (red alga) 5:343 Desmodium 21:525 Desmodium adscendence 21:659;22:519 Desmodium polycarpum DC. 22:519 for convulsions 22:519 Desmodium pulchellum 22:519 for convulsions in infants 22:519 Desmodium styracifloium 25:93
1264
Desmodium triflorum DC. 22:519 for convulsions 22:519 Desmopsamma anchorjkata 26:72 Detraium microcarpum 21:611 Diabrotica undecimpunctata 25:792 Diabrotica virgifera Dithiins-dipsaci 26:867,868 Dianthus barbatus 26:32,55 Dianthus caryophyllus 26:32,594;29:593 Dianthus chinensis 26:3,32,33,34 Dianthus delloides 26:32 Dianthus sp. 5:659 acylated anthocyanins 5:659 malic acid in 5:659 Dianthus superbus var. longicalycinus 26:32,33 Diaperoecia californica 17:90,92 Diaporte helianthi 15:345 Diatriba 25:186 Dicentra spectabilis 27:163 Dicerocaryum zanguebricum 26:1158 Dichroa febrifuga 20:522;22:146 Dichrostachys cinerea L. 22:519 for epilepsy 22:519 Dicraeopetalum stipulare 27:271 Dicranostigma franchetianum 27:162 Dicranostigma lactucoides 27:155,162 Dicranostigma leptopodum 27:162 Dictamnus albus L. 22:519 for hysteria 22:519
Dictydiaethalium plumbeum arcyriaflavin-D from 12:366,370
Dictyoceratida 6:107,111;19:568 Dictyodendrilla cavernosa 18:718 Dictyodendrilla sp. 28:691 Dictyoloma incanescens 26:820 Dictyoloma peruviana 26:820 Dictyoloma vandellianum 26:820 Dictyoptera 22:371 Dictyopteria genus 25:841 Dictyopteris divaricata 6:16,18 dictyopterone from 6:16 [3-dictyopterol from 6:16,18 (-)-zonarene from 6:15 Dictyopteris undulata 6:17 isozonarol from 6:17 zonarol from 6:17 Dictyopteris zonaroides 6:15 (-)-zonarene from 6:15
Dictyostelium 9:220 Dictyostelium discoideum 5:275,384; 25:523;26:80
Dictyota 9:78,79,86 Dictyota acutiloba (-)-dictyolene from 6:27
Dictyota crenulata 5:370,70;6:70 Dictyota dichotoma 9:86,88 Dictyota divaricata 6:52 Dictyota indicia 9:78-81 Dictyota linearis 6:52 (+)-amijitienol from 6:52 dolasta-1 (15)-7,9-trien-14-ol from 6:52 isoamijiol from 6:53 Dictyota spinulosa 5:370 Dictyotaceae dolastanes from 6:52 marine diterpenes from 6:52 Didemnun voeltakowi 25:713 Didemnum 25:878 Didemnum candidum 23:257,259 Didemnum chartaceum 23:248;28:631 lamellarin G 8-sulfate from 28:631 lamellarin sulfates from 28:631 lamellarin B from 28:631 lamellarin C from 28:631 lamellarin L from 28:631 Didemnum chartcium 17:22 Didemnum conchylatum 23:25825:802 Didemnum molle 25:883;28:630 comoramide A from 28:630 comoramide B from 28:630 cyclodidemnamide from 28:630 mayotamide A from 28:630 mayotamide B from 28:630 mollamide from 28:630 Didemnum rodriguesi 25:813,897;28:632 caledonin from 28:632 Didemnum sp. 10:24;25:765.818,874; 28:631,634 anti-human immunodeficiency virus (anti-HIV) activity of 28:631 didemnaketal C from 28:631 didemnoline A from 28:634 didemnoline D from 28:634 polysaccharide kakelokelose from 28:631
1265
Didemnum ternataum 23:234 Didemnum voeltzkowi 10:244 Didicus flavus 23:165 Didymium bahiense var. bahiense 29:252 constituents of 29:252 fruit bodies of 29:252 Didymium iridis 29:248 Didymium minus 29:250 clerosterol from 29:251 clionasterol from 29:251 constituents of 29:250 22,23-dihydrobrassicasterol from 29:251 glycoside glucoclionasterol from 29:251 isofucosterol from 29:251 24-methylenecholesterol from 29:251 poliferasterol from 29:251 Didymium squamulosum 29:247 Dietyosphaeria farulosa 25:898 Digenea simplex 25:846;26:478 Digitalis 2:402,439;21:488; 26:174 Digitalis lanata 15:367,375,377;25:535 Digitalis purpurea 14:439;25:535;27:837 steroidal lactones from 14:439 digitoxin from 5:505 ;5:505 Dilodia gos~ypina 25:131,149 Dilophus 25:690 Dilophus ligulatus 25:690 Dilophus okamurai 25:690 Dinophysis 21:301;27:875 Dinophysis acuminata 5:384 Dinophysis fortii 17:20;25:729 Dinoponera grandis 5:223,224,229,254
Dioclea glabra (Dioclea leiophylla) 29:598 Dioscorea batatas 23:342 Dioscorea collettii var. hypoglauca 21:636
Dioscoreajaponica 21:584 Dioscoreophyllum cumminsii 27:19 monellin from 27:19
Diosma crenulata 29:579 Diospyros 7:406,423 Diospyros abssinica 7:417 Diospyros canaiculata 2:224 Diospyros kaki Thunb 19:246;21:498; 29:588
Diospyros leucomelas 22:105,119,125 Diospyros montana (Ebeaceae) 2:231,22,754;26:804
Diospyros perigrina 29:578 Diospyros usmabarensis F. 7:427,435 22:520 for epilepsy 22:520 Dio~pyros zombensis 7:417,427,429 Dipetallolema viteae 26:487 Diphylleia 26:172 Diphylleia cymosa 5:492 Dipladenia martiana 29:578 Diplococcus ganera 29:311 Diplodia gossypina 25:162,166,168,170 Diplodia maydis 4:600 synthesis of 4:230 Diplophyllum albicans 2:278;24.-183 Diploptera punctata 22:376,382 Diplorhoptrum 6:422,423 Diplosoma sp. 25:821;28:636 diplamine from 28:636 Diplosoma virens 23:244;25:888; 28:644,645; Dipodascus sp. 12:337 Dipolar learsiae 25:788 Diprian pini 27:384 Dipsacus afer 21:672 Dipterocarpaceae spp. 27:766 Dipterocarpus alatus 23:532 Dipteryx alata 29:598 Dirca occidentalis 26:219 genkwanin from 26:219 (+)-lariciresinol from 26:219 sitoindoside II from 26:219 Discodermia 26:1175 Discodermia calyx 27:877;25:731; 26:1204;28:713 Discodermia dissoluta 21:411;26:1205 discodermide from 2 ! :411 Discodermia kiiensis 26:1201,1204 Discodermia polydiscus 25:763 Discodermia sp. 21:252;26:1201,1202 calyculins E,F from 21:252 Distemonanthus benthamianus 5:676-681 Distolasteria nipon 7:299;15:55 Distyophaeria sericea 25:722 Distyostelium 25:526 Distyota ciliolata 25:722 Dithiins dipsaci 26:437
1266
Dittrichia viscosa 22:428 quercetin from 22:428 3-O-methylquercetin from 22:428 7- O-methylaromadendrine from 22:428 Dittrichia viscosa 25:613 Ditylenchus destructor 26:460 Ditylenchus dipsaci 26:493 Diuranthera major 21:675 Diuranthera major diuranthoside B from 21:675 Dodonaea glabra 24:151,152 dodonosides A from 24:151,152 dodonosides B from 24:151,152 Dodonaea saponins 15:191;21:657 Dodonaea viscosa 7:139,427;25:276 Dolabella 25:724 Dolabella auricularia 19:557,19:601; 25:716,760,763,878,887;28:648 sequence of 28:648 synthesis of 28:648 Dolabella auricularia 4:87,420,421; 28:649 Dolichodenis clarkii 5:224,253 Dolichos biflorus 29:598 Dolichos kilimandscharicus 7:432,433 Dolichos lablab L 19:247 Dolichos marginata ssp.erecta 7:413,414 Dorestenia sp. 29:780 Doris verrucosa 28:651 9-(5-deoxy-5-methylthio-[~-Dxylo furanosyl)adenine from 28:651 digestive glands of 28:651 Doris verrucosa 25:829 Dorstenia 29:793 Dorstenia proropens 29:774 Dorstenia barnimiana 29:795 Dorstenia barteri 29:777 Dorstenia brasiliensis 29:795 anticancer activities of 29:797 antileukodermic activities of 29:797 antimutagenic activities of 29:797 anti-tumor activities of 29:797 artemicide activities of 29:797 bacteriophagicide activities of 29:797 cytotoxic activities of 29:797
hepatoprotective activities of 29:797 radical-scavenging activities of 29:797 uses of 29:798 viricide activities of 29:797 Dorstenia bryioniaefolia 29:795 Dorstenia ciliata 29:772 Dorstenia contrajerva 29:763 Dorstenia dinklagei 29:787 Dorstenia drakena 29:763 Dorstenia elliptica 29:763 Dorstenia excentrica 29:763 Dorstenia 29:778 Dorstenia gigas 29:763,767 Dorstenia kameruniana 29:783 Dorstenia lindeniana 29:763 Dorstenia mannii 29:781,782 Dorstenia poinsettifolia 29:795 Dorstenia psilurus 29:792 Dorstenia sp. 29:763 Dorstenia tayloriana 29:793 Dorstenia zenkeri 29:786 Dracaena loureiri 5:17;28:234 in apple juice 28:271 in cider 28:271 in pomace 28:271 nothofagin from 28:272 Dracena mannii 21.660 spiroconzole A from 21:660 Drechslera gigantea 6:555 Drechslera rostrata 26:227 Drechslera spp. 26:468 Drimys species 4:404 Drimys winteri Forst 4:418 Drosera capensis L. 26:115;830:345 cell suspensions of 30:345 Drosophila 22:682;25:389;30:777 Drosophila melanogaster 18:698;29:55; 29:31 alkaloids activity in 29:56 ampelopsin B (distilbene) activity in 29:55 apiole activity in 29:56 bisphenol A activity in 29:56 carnosiflosides activity in 29:55 cis-resveratrol (monostilbene) activity in 29:55 croweacin activity in 29:56
1267 cucurbitacins activity in 29:55 deacetylpicracin activity in 29:55 diethylphthalate activity in 29:56 2,3-dihydro-3 [3-methoxyichromolide activity in 29:55 2,3-dihydro-313-methoxywithacnistine activity in 29:55 2,3-dihydro-3[3-methoxywithaferin A activity in 29:55 23,24-dihydrocucurbitacin F activity in 29:55 2,6-dime tho xy-3,4- methylenedioxy- 1-(2-propenyl)benzene activity in 29:56 ecdysteroiods activity in 29:55 24-hydroxycarthamosterone activity in 29:55 industrial compounds activity in 29:56 isoasarone activity in 29:56 3-epi-isocucurbitacin D activity in 29:55 isomitraphylline activity in 29:56 isopteropodine activity in 29:56 kobophenol B (tetrastilbene) activity in 29:56 limonoids activity in 29:55 lindane activity in 29:56 marginatine activity in 29:56 cis-miyabenols (tristilbene) activity in 29:55 phenylalkanoids activity in 29:56 pipermargine activity in 29:56 prieurianin activity in 29:55 rohitukin activity in 29:55 stilbenoids activity in 29:55 suffruticosols (tristilbene) activity in 55 c~-viniferin (tristilbene) activity in 29:55 withanolides activity in 29:55 Drupella fi~agum 25:792 Drymis winteri 30:206 anti-inflammatory properties of 30:207 antinociceptive properties of 30:206 Dryophanta divisa 29:589
Dryopteris filixmas 26:431 Duasmodactyla kurilensis 7:279,91,153 Duboisia 17:395 Duboisia leichhardtii 22:742 Duboisia myoporoides 22:742 Ducrosia anethifolia 23:341 Duguetia panamensis 9:402 Dumasia truncata 25:106 Dunalia australis 20:191,194 Dysdercus chaluensis 22:387 Dysdercus cingulatus 22:387 Dysdercus fluvoniger 22:387 Dysdercus intermedius 22:387 Dysdercus supersetitisus 22:387 Dysidea 17:10,11;28:676 Dysidea arenaria 25:714 Dysidea avara 5:433,438;21:252; 25:693,814,815 ;28:668 DysideaJfagilis 6:69;28:702 nakafuran-9 from 6:69 (+)-upial from 6:65 Dysidea herbacea 4:404;21:283,284, 310,365 ;25:691,692,697,776,801,815; 26:463 ;28:142,665,666 dysideathiazole from 28:665 13-demethylisodysidenin from 28:666 13-demethyldysidenin from 28:666 13-demethylisodysidenin from 28:666 13-demethyldysidenin from 28:666 isodysidenir from 28:665 immunosuppressant activity of 28:142 molluscidal activity of 28:142 9-monodechloro- 13-demethylisodysidenin from 28:666 11-monodechloro- 13-demethylisodysidenin from 28:666 polychlorinated peptides from 28:665 (22R,23R)-22,23-methylene cholesterol from 9:37 Dysidea sp. 21:301;25:264,692,693,698, 815,869,896;28:666 15-acetylthioxyfurodysinin lactone from 28:667
1268
[3-adrenoreceptor agonist from 28:668 barbaleucamide A from 28:668 benzothiazole S 1319 from 28:668 dysideaproline A from 28:668 dysideaproline B from 28:668 dysideaproline C from 28:668 dysideaproline D from 28:668 dysideaproline E from 28:668 dysideaproline F from 28:668 from Okinawa 28:668 proline-derived analogues of dysidenin from 28:668 Dysidia chlorea 25:801 Dysosma 26:172 Dysoxylum 21:124,127 Dysoxylum binectariferum 21:134,147 Dysoxylum lenticellare 6:487 Dysoxylum malabaricum 21:134,152 Dysoxylum spp 3:456 Dytiscus marginalis 5:700
Ecballium EETI-II 29:615 Ecballium elaterium 20:13;29:615 Echinacea angustifolia Echinacea augustifolia DC. 22:393; 24:689;29:684
Echinacea sp. 29:683 Echinaster brasiliensis 15:55 Echinaster luzonicus 7:294 Echinaster sepositus 7:294,298;15:59 Echinochloa crusgalli (L.) 27:217 Echinochloa frumentacea 24:57,60 Echinoclathria sp. 25:814 Echinoclathria subhispida 28:705 Echinocystis lobata 29:615 Echinocystis macrocarpa 7:330 Echinodictyum sp. 25:900;28:697 echinosulfonic acid A from 28:697 echinosulfonic acid B from 28:697 echinosulfonic acid C from 28:697 echinosulfone from 28:697 Echinophora lamellosa 7:136 echinolactones A,B from 7:136 glycyrrhetic acid from "/:136 smilagenin from 7:136 Echinops echinatas 22:117,119
Echium piantagineum 19:247 Echium sp. 26:872 Echium vulgare 22:520 Echium wildpretti 26:874 Eciton hamatum 5:250 Ecklonia stolonifera 19:553 Ecteinascidia turbinata 21:322;23:253; 25:707,825;28:640,641 antitumor activity of 28:640 ecteinascidins from 28:640,641 Ectocalpus siliculosus 21:305,306 Ectyoplasia ferox 26:66 Eedeoma pulegioides L 22:522 Egregia menziessi 19:554 Eichhornia crassipes 26:359 Eimeria 26:804 Eimeria tenella 17:376 Eisenia andrei 30:828 from Lumbricidae family 30:828 Eisenia fetida 30:826,828,829,832 EFE component A of 30:829 F-II homolog of 30:832 fibrinolytic activity of 30:826 from Lumbricidae family 30:828 isozymes of 30:826 Ekebergia senegalensis A. 2:117,2:118, 120,2:269;22:520 for epilepsy 22:520 Elaeocarpus ganitrus 22:520 for epileptic fits 22:520 Elaeocarpus sphaericus 22:520 for epilepsy 22:520 Elaeocarpus tuberculantus 22:520 for epilepsy 22:520 Elaeodendrom buchanani 23:655
Elaeodendron balae (Cassine balae) 149,150
Elaeodendron buchananii 23:669 insect antifeedant sesquiterpenes from 23:669 Elaeodendron capense 23:655 Elaeodendron glaucum 5:757,152;23:655 Elaeodendron schiveinfurthianum 23:655 Elaodendrum 18:741 Eldana saccharina 11:414 eldanolide from 3:168;11:414 synthesis of 3:168 Eleocarpus 27:250 Eleocharis miovcarpa 26:361
1269
Elettaria cardamonum 21:614;26:474; 27:374 Elettaria sp. 21:599 Eleusine coracana 29:601,617 Eleutherobia aurea 25:690 Eleutherococcus senticosus Harms
(Acanthopanaxsenticosus)
Epilachna varibestis 7:396;22:398; 30:333
Epilobium capense 23:404 Epipactis helleborine 30:405 Epipedobates tricolor 19:66,19:146; 25:791 ;27:247;27:247;
5:505,514,515,521,523,524,544
Epiphyas postvittana 26:231 Epipolasis kushimotoensis 25:853;28:662
dysodanthin A&B from 26:212 megaphone acetate from 26:212 Endomyces spp. 2:323 Endomycopsis fibuliger 5:280,282 Endosperium diadenum 29:100 Endospermum diadenum 29:100 Engelhardtia chrysolepis 15:31;27:18; 29:583 huangqioside E from 27:18,35 neoastilbin from 27:18,35 Entada 15:191,214 Entamoeba histolytica 6:485,398;23:473; 26:836,1063 Entandrophragma 9:102 Entandrophragma utile 9:95 Enterobacter cloacae 12:63;25:258,259; 26:402,1091 Enterobacter sp. 25:170,171 Enterococcus faecalis 10:117,400, 20:712;25:776,778 Enterococcus faecium 25:776 Enterolobium contorsiliquum 29:604 Enterolobium EcTI 29:604 Epeolus cruciger 5:223,224,231,253 Epeolus variegatus 5:223,224,231,253 Ephedra sinica Stapf 5:505 Ephedra spp. 26:235 ephedradine B from 26:235 Epicoccum purpurascens 21:221 Epidermophyton fluccosum 26:227,228
[3-phenylethylamine of 28:662 epipolasins A of 28:662 epipolasins B of 28:662 Epipolasis sp. 28:699 Eragrostis curvula 26:469 pyrocathecol from 26:469 Eremanthes elegnus 24:6 Eremanthus mattogrossensis 29:90 Eremanthus glomerulatus 7:427 Eremmophla aureonontata 5:223,225,253 Eremophila 15:225-282 Eremophila abietina 15:227 Eremophila alternifolia 15:225,232 Eremophila caerulea 15:227,281 (+)-fenchone from 15:227 oleanolic acid from 15:281 ursolic acid from 15:281 Eremophila clarkei 15:253 Eremophila cuneifolia 15:227,248 Eremophila dalyana 15:225,227 Eremophila decipiens 15:263 Eremophila dempsteri 15:227,254 Eremophila drummondii 15:244,248 (+)-calamenene from 15:244 serrulatane from 15:259 (+)-spathulenol from 15:248 Eremophila duttonii 15:225 Eremophila elderi 15:225 Eremophila exilifolia 15:252 Eremophila foliosissima 15:255 Eremophila fraserii 15:248,252,271 Eremophila freelingii 15:252,271 eremolactone from 15:252,271 freelingyne from 15:233 Eremophila georgei 15:269,271 Eremophila gilessi 15:225 Eremophila glutinosa 15:252 Eremophila granitica 15:254 Eremophila inflate 15:229 Eremophila interstans 15:245,247
Elsinoe leuco~pila 5:278 Emericalla uniquis 25:780 Emericellopsis sp. 21:224 Emicarpus anacardium L. 22:532 Empidonnax hammondii 5:836 Encephalartos 26:1157 Encephalartos friderici-guilielmi 26:1158 Encephalartos longifolius 26:157 Encephalitizoon inteslinalis 26:788 Endlicheria dysodantha 26:211
1270
Eremophila latrobei 15:229,232,258 biflorin from 15:258 Eremophila longifolia 15:225 Eremophila maculata 15:226,229 Eremophila miniata 15:229 Eremophila mitchelli 15:226,281 Eremophila paisley 15:248 Eremophila petrophila 15:252 Eremophila platycalyx 15:281 Eremophila racemosa 15:248 (+)-spathulenol from 15:248 Eremophila rotundifolia 15:233 freelingyne from 15:233 Eremophila scoparia 15:227,232,244 Eremophila serrulata 15:257,259 Eremophila spp. 8:423 (+)-isoeremolactone 8:423 Eremophila virgata 15:245 Eremophila viscida 15:260 Eria ravanica 23:522 Erica andevalensis 22:428 myricetin-3-O-D-galactoside from 22:428 Erica andevalensis 25:612 Erigeron philadelphicus 26:436 Eriobotrya japonica 17:115,118119;19:247 Eriosema tuberosum 29:579 Ervatamia coronaria 5:135,136,158, 171,172 Ervima coli 25:220,258,259,394,450, 821,928 Erwinia amylovra 25:394 Erwinia carotovora 25:394 Erwinia chrysanthemi 25:394 Erwinia herbicola 17:637 Erwinia 4:434 Erycibe elliptilimba 21:751 Erycibe obtusifolia 21:751 baogongteng A from 21:750 Erylus formosus 26:80,85 Erythema infectiosum 30:394 Erythrina abyssinica 29:781 Erythrina 3:455-493 Erythrina arborescens 3:455-493 synthesis of 3:455-493 Erythrina berteroana 7:417 Erythrina burana 20:496 Erythrina caffra 29:604
Erythrina crysta - galli L. 3:476 Erythrina ETI-a ETI-b 29:604 Erythrina latissima 29:604 Erythrina lithosperma 3:479 Erythrina melinoniana 22:27 Erythrina stricta 22:520 for epilepsy 22:520
Erythrina type 11:229 Erythrina variegata L. 22:520; 29:598,604
Erythroxylon 21:488 Erythroxylum spp. 22:520,718,721 Esbericum 22:698 Escallonia spp. 29:572 Escherichia chrysanthemi 25:394 Escherichia coli 4:433;5:367,429,434; 7:39,44,46,50,52,54 ;9:293,308,537,59 2,593,596,603,604,606;8:102;11:182, 214;12:63,95-109;13:157,162,164, 261,262,283;17:378;18:709,722,727; 18:921 ;19:601 ;20:712;21:174,175; 21:299,573,600;22:623,627 ;23:67, 137,235,474,533 ;24:713;25:257,319, 765,775,925,948;26:330,331,333,402, 556,605,802,1092,1093,1135,1263, 1269,1271,1272,1274,1278;27:305; 28:519;30:739,843 antibacterial activity against 30:739 antifungal activity against 30:739 biological activity of 30:843 Escherichia coli BFI-ATPase 10:439 Escherichia faecilis 25:259 Eschscholtzia californica 27:159 Eschscholtzia 27:163 Eschscholtzia sp. 27:159 Escobedria scabrifolia 30:528 azafrin from 30:528 Eteromorpha prolifera 25:691 Eubacterium saburreum 4:195 Eucalptus citriodora 25:32 Eucalyptus 29:589 Eucalyptus alba 23:405,413 Eucalyptus amplifolia 24:234;29:111 derived from monterpene (or sesquiterpene) 24:235 dialdehyde 24:235 Eucalyptus blakelyi 24:234;29:111 activity in EBV bioassay system
1271 29:111 from Euglobal-BI-1 29:111 Eucalyptus calophylla 19:247 Eucalyptus camaldulensis 28:427 Eucalyptus 27:755 Eucalyptus globulus 24:232;28:402 Eucalyptus grandis 24:234,240 ; 26:445;29:111 activity in EBV, lung-2, skin-l, skin-3 bioassay systems 29:111 euglobals from 29:111 Eucalyptus haemastoma 26:696 Eucalyptus incrassata 24:234 Eucalyptus marinata 19:247 Eucalyptus polybractea 24:232 Eucalyptus robusta 23:405 Eucalyptus smithii 24:232 Eucalyptus sp. 21:526,527;29:83 Eucalyptus spathulata 15:248 (+)-spathulenol from 15:248 Euchresta formosana 29:781 Euclea natalensis 30:328 isodiospyrin from 30:328 Eucommia ulmoides 5:505,521525,530,544 ;20:613,647-648; 26:235 (• diglucoside from 26:235 Eudistoma album 23:263 Eudistoma cf. rigida 10:247;28:635 iejimalide C from 28:635 iejimalide D from 28:635 Eudistoma divaceum 25:902 Eudistoma fragum 23:257 Eudistoma gilboverde 28:634 methyleudistomidin C 28:634 Eudistoma glaucus 5:353;23:262,263; 25:758,817;28:634 eudistomidin C from 28:634 Eudistoma olivaceum 5:417,418,246,100; 21:260,321 ;25:816;28:633 13-carboline alkaloids from 28:633 eudistomins from 21:260 N( 10)-methyleudistomin E from 28:633 Eudistoma sp. 12:366,370,10:247 25:820,834;28:637 desmethylvaracin from 28:637
Eudistoma taoelensis 21:260 N-demethyl staurosporine from 21:264 3-hydroxy staurosporine from 21:264 staurosporine from 21:254,264 Eudistoma taoelensis 21:264 Eudynamis scolopacea 5:837 Eugenia 21:600 Eugenia caryophyllata 21:585 Eugenia 27:755 Eugenia unoqora 14:450;23:405 Euglena gracilis 23:124;26:363; 0:397 (1-3)-13-D-glucan from 30:397 Euglena viridis 6:150 Eumenes fi'aternus 5:224,225,232,253 Eumycota 9:202 EuniceaJi4sca 21:276;29:690 Eunicea 10:9 Eunicea succinea 26:83 Eunicea taurneforti 20:492;25:690 Eunicella cavolinii 25:690 Eunicia succinea 10:7 Euodynrus fuscus 5:224,253 Euonomynus 18:741 Euonymus alatus 23:655 Euonymus atropurpureus 23:655 Euonymus bungeanus 23:668 antifeedant sesquiterpenes from 23:668 insecticidal sesquiterpenes from 23:668 Euonymus europaeas 23:655,674 Euonymus fortunei 23:668 Euonymus tingens 30:668 tingenone from 30:668 Euonymus verrucosus 23:656 Eupatorium adenophorum 5:28 Eupatorium articulatum 22:353 Eupatorium fortunei 24:273 Eupatorium gracile 29:573
Eupatorium maculatum 20:145 Eupatorium quadrangulare 24:103 Eupatorium trapezoideum 15:247 Eupatorsum inulaefolium 22:349
5,6,3 '-trihydro xy- 7,4 '-di methyoxyflavone pedalitin from 22:349
1272
Eupentacta fraudatrix 7.275,276;21:314 28:598 from calcigeroside B 28:598 from calcigeroside C~ 28:598 from calcigeroside D~ 28:598 from cucumarioside G2 28:598 Euphorabia characias 26:1263,1277 Euphorbia 12:233,234;25:242 Euphorbia acaulis 9:265,267,288 Euphorbia brachypoda 28:400 Euphorbia caudicifolia 9:265 Euphorbia fidjiana 9:265-292;15:385 Euphorbia fisheriana 22:520 Euphorbia genera 27:830 Euphorbia helioscopia 9:265;23:406 Euphorbia hirta L. 22:520;23:405 for convulsions 22:520 Euphorbiajolkinii 9:265 Euphorbia lagascae 9:391 Euphorbia laterifolia 2:262 Euphorbia lathyris 24:273 Euphorbia maculata 23:406 Euphorbia maddeni 25:594 Euphorbia milii 5:678 Euphorbia myikae 22:520 Euphorbia nerifolia 7:152-154 Euphorbia nyikae Pax. 22:520 for epilepsy 22:520 Euphorbia obovalifolia 28:400 Euphorbia obovalifolia's 28:400 Euphorbia pallasii 9:265,288 Euphorbia pekinensis 29:579 Euphorbia poisonii 2:261 Euphorbia prostrata 23:406 Euphorbia quiquecostata 29:103 Euphorbia resinifera 30:193 resiniferatoxin from 30:193 Euphorbia species 9:265,267,20:19 Euphorbia tirucalli L. 22:520;23:406 Euphorbia triaculeata 9:265 Euphorbia watanabei 23:406 Euphorbiaceae 25:242,243,245 Euphorblaceae phyllantus 22:720 Euplaxaura erecta 14:315 Eupomatia laurina 24:790 Euponera sp. 5:224 Euretaster insignis 7:304,94,45 Euroglyphus maynei 28:417 Europhthalma 6:422-434
Europium sp. 5:325 Eurotium chevalieri 26:1091,1093,1094, 1097-1099
Eurycoma longifolia 7:393;23:300; 24:282
Euryspongia 28:667 15-acetylthioxyfurodysin from 28:667 Euryspongia arenaria 25:703 Euryspongia deliculata 25:694 Euryspongia species 4:404 Euterpe spp. 22:355 Euthyroides episcopalis 25:862;28:621 euthyroideones from 28:621 Eutypa lata 21:204 Evasoteria troschelii 25:813 Evernia prunastri 5:310-312,322 Evodia rutaecarpa 26:487 Evodiopanax innovans 29:573 Excoecaria agallocha 7:176178,180,183,195; 22:520;9:102 constiutents activity in EBV, skin-1 bioassay systems 29:102
(13R,14R)-ent-8ot,13 ;14,15 -diepoxy- 13-epi-labdan-3f3-ol from 29:102
ent- 13-epi-8,13-epoxy-2,3secolabd- 14-ene-2,3- dioic acid 3methy]
ter from 29:102
ent- 13-ept-8,13-epoxy-2-hydoxylabd- 1-en-3-one from 29:102
ent- 13-epi-8,13-epoxy-2-oxa-3oxolabd- 14-ene- 1R-carboxylic acid methyl from 29:102 excoecarin A from 29:102 excoecarin B from 29:102 excoecarin F dimethyl ester 29: from 102 excoecarin H methyl ester from 29:102 excoecarin from 29:102 ent- 16-hydroxy-3-oxo- 13-epimanoyloxide from 29:102 11 [3-hydroxy-ribenone from 29:102 ent- 13-epi-manoyloxide from 29:102 for epilepsy 22:520
1273 ribenol from 29:102 ribenone from 29:102 Excoecaria kawakamii 23:406 Exophiala dermatitidis 28:476 Exophiola pisciphila 25:723 f. sp. gladioli 25:307 f. sp. melonis 25:307,411 f. sp. niveum 25:307 f. sp. tuberosi 25:307 sp. lycopersici 25:295,299,307, 312-314,316,318
Fagara macrophylla 7:427;27:168 Fagara sp. 27:164 Fagara xanthoxyloides Lain. 27:159 Fagaropsis angolensis 27:164 Faglis sylvatica 25:662 Fagopyrum esculentum 21:527;29:608 Fagraea racemosa 26:268 (+)-epiresinol from 26:268 (+)-isolariciresinol from 26:268 (+)-pinresinol from 26:268 Falcaria sp. 27:686 Falcaria vulgaris 27:422 Fallopiajaponica 22:608 Fallopia sachalinenesis 22:608 Fames spp. 24:172 Farmosan gorgonian 25:690 Fascaplysinopsis sp. 5:411 Fasciospongia cavernosa 25:688,697,703 Fasciospongia rimosa 19:568;25:874 Feronia elephatum 21:600 Ferula akitschkensis 5:723 Ferula alliacea 22:521 for epilepsy,hysteria and infantile convulsions 22:521 Ferula arrigonii 24:81
Ferula communis subs.communis 8:57;5:723
Ferula elaeochytris 5:723 Ferula foetida 22:521 for convulsions 22:521
Ferula galbaniflua 19:157-158;22:521 for epilepsy 22:521
Ferulajaeschkeana 5:725 Ferula karatavika 1:660 Ferula lancerottensis 5:725,727 Ferula lapidosa 5:723
Ferula linkii 5:725,734;29:91 Ferula pallida 5:723 Ferula rubicaulis 19:158 Ferula sp. 5:721,732 Ferula tenuisecta 5:723 Ferula tingitana 5:723 Ficus capensis 22:521 for convulsions 22:521
Ficus costata 2:231 Ficus diversiformis 2:231 Ficus elastica 8:66 Ficus fergusoni 2:231 Ficus microcatpa 29:788 Ficus pyrifolia 20:522 Filipendula ulmaria 23:397 Fischerella ambigua 23:342;25:792; 26:364
Fischerella 26:366 Fischerella major 25:802 Fischerella muscicola 25:802;26:364,366 Flammulina velutipes 5:289 Flavobacter dehydrogenans 9:417,418 Flavobacterium sp. Flavobacterium sp. 7:330,336,341-345, 347-351,358,360,363 ;25:868
Flemingia congesta 29:775 Flemingia rhodocalpa 29:775 Flemingia strobilifera 22:521 for epilepsy, hysteria and nocturnal epilepsy 22:521 Flemingia wallichi 29:775 Flexibacter elegans 9:323 Flueggea virosa 22:521 for epilepsy 22:521 Flustra foliacea 17:80,85,87,102,103;
18:689,692,693,708,725 Flustra papyracea 17:86 Foeniculum 21:619 oil of 21:619
Foeniculum vulgare Mill 5:473;21:599; 27:16;28:408
Fogs grandifolia 5:472 Fomes annosus 21:212,232 Forsylhia intermedia 26:156,174,177,223 (-)-arctigenin from 26:223 26:327
Forsythia Forsythia Forsythia Forsythia
suspensa var.Jortunei 5:475 intermedia 5:489-491,492,494 koreana 26:237
1274 Forsythia mandshurica Rupr. var.japonica Maxim 5:505,514-516,520,523-525,531 Forsythia spp. 5:511-513,521 26:156, 157,235 pinoresinol monoglucoside from 26:235 Forsythia suspensa 5:489,506,522,592, 616;21:595 ;24:855;26:156,237,241 inhibition of cyclic adenosine monophosphate (c-AMP) phosphodiesterase 24:855 Forsythia viridissima Forsythia viridissima Lindley 5:505,506, 514,522;26:237 Fosarium oxysporum 25:314 Fostreus 27:883 as phosphatase inhibitor 27:883 Fragaria spp. 29:571,579,582 Fraxinus 26:327,333,343 Fraxinus bungeana 26:317 Fraxinus chinensis 26:317 Fraxinus formosana 26:327 Fraxinus insularis 26:321 insularoside from 26:321 Fraxinus japonica Blume 5:505,514, 515,520,521,523-525,531 Fraxinus ornus 26:313-319,327,328,330, 332,334-340,341,343-345 Fraxinus rhyncehophyllus 13:660 Fraxinus spp. 26:315-318 Fraxinus stylosa 26:317 cichorin from 26:314 esculetin from 26:314 fraxetin from 26:314 fraxin from 26:314 hydroxycoumarin esculin from 26:314 quercetin from 26:314 quercetin-3,7-digalactoside from 26:314 quercetin-3-galactoside from 26:314 quercetin-3-glucoside from 26:314 rhamnetin from 26:314 rutin from 26:314 Fraxinus uhdei 26:321 uhoside from 26:321 ;28:598 from calcigeroside C~ 28:598
from calcigeroside D1 28:598 from cucumarioside G2 28:598 Fromia monilis 15:60 Fructus schisandraei 26:233 Frullania dilatata 2:280,607 Frullania nisquallensis 2:280,471 Frullania tamarisci 2:278,280;9:254; 18:607,614,623 Fuchsia 29:572 Fucus garderi 26:1152 Fucus vesiculosus 25:717,725 Fulica atra 5:837 Fuligo septica 21:413,29:236 fuligorubia A from 21:413 Funco oreganus 5:836 Fusaria sp. 24:942 fusicoccins from 24:942 Fusarium 6:219-259,201-218;9:201-208; 13:519,524-529;22:57;21:213,216, 227,233;26:464,482;27:158 Fusarium acuminatum 9:204,213;13:535 Fusarium avenaceum 9:204,205,213,214; 13:526,535 Fusarium compactum 13:536;29:575 Fusarium crookwellense 9:205;13:526 fusarin C from 13:526 Fusarium culmorum 4:648,250,204-208, 212;13:519,520,526;27:225,382 Fusarium equiseti 9:204;13:543,545; 28:121 HIV inhibitory activity of 28:121 Fusarium graminearum 9:204-208,216, 524,543 Fusarium heterosporum 29:111 Fusarium larvarum 15:381,386 Fusarium lini 18:807 monohexosylceramides fiom 18:807 Fusarium merismoides 9:204 Fusarium moniliformes 9:203-205,214, 215;13:524,526,530 Fusarium nygamai 13:530 Fusarium oxysporum 9:204;21:189,196, 199,210,217,223,232 ;23:139,355; 25:293,295,296,299,305,311,312,313,3 17,319,320,322 Fusarium oxysporum f. sp. cucumerinum 9:238 Fusarium poae 9:204,314,315,526
1275
Fusarium proliferatum 13:530 Fusarium roseum 13:543 Fusarium sambucinum 9:204;13:526,543; 25:317 Fusarium semitectum 9:204 Fusarium solani 9:204;25:303,305, 307,314,316,317;26:404,405,418 monohexosylceramides from 18:807 Fusarium sporotrichioides 6:247,204, 205,208-213 ;13:526 Fusarium subglutinans 13:530 Fusarium tricinctum 9:205 Fusarium udum 21:240 Fusicoccum amygdali 15:385 Fusidium coccineum 21:231 Fusobacterium nucleatum 4:195 Gaeumannomyces graminis 25:304 Gaeumannomyces graminis var tritici 21:186,196,199,204,210 Galaxura marginate 25:704 Galeopsis angustifolia 25:251 Galeopsis ladanum L. 22:521 Galinum sinaicum 26:220 bis-glucoside derivatives from 26:220 Galium 4:400;26:631 Galium sylvaticum 22:521 Galium verum L. 22:521 for epilepsy and hysteria 22:521 Galleria mellonella 22:384 Galphimia glauca 22:521 for epilepsy 22:521 Gambierdiscus toxicus 21:300;25:730 Gambusia ajfinis 21:365 Ganodermajaponicum 23:115 Ganoderma lucidum 22:132;23:126,133; 26:449;30:56,58,60 antimetastatic effect of 30:58,60 antitumor effect of 30:58 effect on blood glucose 30:58 in treatment of arteriosclerosis 30:58 in treatment of arthritis 30:58 in treatment of bronchitis 30:58 in treatment of cancer 30:58 in treatment of diabetes 30:58
in treatment of hyperlipidemia 30:58 in treatment of hypertension 30:58 triterpenoid fractions of 30:60 triterpenoid from 30:56 Garcinia 7:444 Garcinia cambogia 22:658 Garcinia cowa 26:805 Garcinia gerrardii 7:444,445,457 Garcinia huillensis 22:658 Garcinia indica 22:658 Garcinia livingstonei 22:659 Garcinia mangostana 4:382,384;27:902; 29:573 Garcinia mannii 22:658 Garcinia ovaliJblia 22:658,659 Garcinia polyantha 22:658 Garcinia spicata 5:757,758 Garcinia staudtii 22:658 Garcinia subelliptica 22:660 Garcinia thwaitesii 5:757,758 Garcinia xishuanbannanensis 22:658 Gardenia cramerii 5:756,757 Gardenia fosbergii 5:756,757 Gardeniajasminoides Ellis 16:298 Gardenia sp. 5:756,757 Gardneria nutans 15:491 Garrya 6:174 Garuga gamblei 17:370, Garuga pinnata 17:370,375-376 Garuga pinnata 26:899 Garuga sp. 17:375;26:899 Gastrodia elata 25:529 Gaultheria procumbens 21:619 Geigeria burkei 14:450 Geigeria species 20:10 Geissospermum laeve 1:124 Geissospermum vellosii 1:124 Gelonium multiflorum 9:265 Gelsemium 15:465-515 Gelsemium elegans 15:466,472,473 akuammidine from 15:466 gelsemamide from 15:472,473 humantenine from 15:472 koumine from 15:475,476 11-methoxygelsemamide from 15:472,473 16-epi-voacarpine 15:469 Gelsemium rankinii 15:465
1276
Gelsemium sempervirens 1:125,465-467 Genatiana macrophylla 25:476 Genista cinerea 27:272 Genista rumelica 22:428;25:612 luteolin, luteolin-7-glucoside and genistein from 22:428 Gentiana compestris 22:521 Gentiana crassicaulis 22:521 for convulsions 22:521 Gentiana dahurica 22:521 for convulsions 22:521 Gentiana decumbens L. 22:521 for convulsions 22:521 Gentianafetisowii Regel 22:521 for convulsions 22:521 Gentiana macrophylla 22:521 for convulsions 22:521 Gentiana sp. 5:651;23:564;25:471 Gentiana tibetica King 22:521 for convulsions 22:521 Gentiana wutaiensis 22:522 for convulsions 22:522 Gentianaceae 25:471 Genus Astragalus 27:251,443,446 abrisapogenol B from 27:443,453 astragenol from 27:449 complogenin from 27:453 9,19-cyclo-5c~,9[3-1anostane from 27:447 cyclocanthogenin from 27:448 cycloalpigenin from 27:452 cycloalpigenin B from 27:449 cycloalpigenin C from 27:449 cycloalpigenin D from 27:449 cycloasgenin A from 27:449 cycloasgenin B from 27:558 cycloasgenin C from 27:448 cycloastragenol from 27:449 cyclogalegenin from 27:450 cycloorbigenin A from 27:452 cycloorbigenin B from 27:452 cyclopycnanthogenin from 27:450 dasyanthogenin from 27:451 3-dehydrocycloasgenin from 27:448 dihydroycloorbigenin A from 27:452 glycyrrhetic acid from 27:453 medicinal uses of 27:447
oleanolic acid from 27:453 oxytrogenin from 27:453 quisvagenin from 27:450 sapogenin from 27:448 sapogenin II from 27:453 saponins from from 27:446 soyasapogenol B from 27:453 terpenoid sapogenins from 27:446 Genus Bupleurum L. 27:660 Genus Dorstenia 29:761 analgesic activities of 29:761 anti-infective principles from 29:761 anti-inflammatory activities of 29:761 anti-oxidant activities of 29:761 anti-rheumatic remedies from 29:761 anti-snakebite principles from 29:761 as chalcones source 29:761 as flavanones source 29:761 as flavones source 29:761 as flavonols source 29:761 as geranyl-substituted coumarins source 29:761 as prenyl-substituted coumarins source 29:761 chemistry of 29:761 cytotoxic activities of 29:761 5,3'-digeranyl-3,4,2',4'-tetrahydroxychalcone from 29:761 O-[3-(2,2-dimethyl-3-oxo-211furan-5-yl)butyl]bergaptol from 29:761 7,8-(2,2- dimethylpyrano-4 'methoxyflavanone (dorspoinscttifolin) from 29:761 3 ', 4 '-(2,2- dimethylp yr ano- 6prenyl-7-hydroxyflavonone from 29:761 ethnomedical information of 29:762 fig family of 29:762 in skin diseases 29:762 mulberry family of 29:762 occurrence of 29:761 pharmacology of 29:761 stereochemistry of 29:765
1277 structure of 29:765 to treat rattlesnake bites 29:765 Genus Hernandia 30:563-580 (-)-laetine from 30:564 (+)-actinodaphnine from 30:563 (+)-corytuberine from 30:563 (+)-hernagine from 30:563 (+)-hernandaline from 30:563 (+)-hernovine from 30:564 (+)-isoboldine from 30:564 (+)-isocorydine from 30:564 (+)-laurotetanine from 30:564 (+)-magnoflorine from 30:564 (+)-N-formyldehydroovigerine from 30:563 (+)-N- formylnomantenine from 30:563 (+)-N-formylovigerine from 30:563 (+)-N-hydroxyhemangerine from 30:564 (+)-N-methyl-6,7-dimethoxyiso30:quinolone from 30:564 (+)-N-methylactinodaphnine from 30:564 5,6-dimethoxy-N-methylphthalimide from 30:563 6,7- dime tho x y-N- methyli soquinoline from 30:563 7- formyldehydrohernangerine from 30:563 7- formyldehydronornantenine from 30:563 7-formyldehydroovigerine from 30:563 7-hydroxy-6-methoxy- 1methylisoquinoline from 30:564 alkaloids from 30:563 antiplatelet aggregation effect of 30:560 atheroline from 30:563 backebergine from 30:563 benzenoids from 30:567 constituents of 30:563-570 dehydrohernandaline from 30:563 demethylsonodione from 30:563 hemandonine from 30:564 hemangerine from 30:564 hernanymphine from 30:564
isoindole from 30:563 isoquinoline from 30:563-567 laetanine from 30:564 laudanosine from 30:564 lignans from 30:567 lindearpine from 30:564 monoterpene from 30:569 N-(N-methylcarbamoyl)-Omethylbulbocapnine from 30:564 N-formylnornantenine from 30:563 N-hydroxyovigerine from 30:564 N-methylcorydaldine from 30:564 pyridine from 30:567 sterols from 30:569-570 Genus Hypericum 30:607,619 hypericin from 30:607 isohypericin from 30:607 pseudohypericin from 30:607 xanthones 30:619 Genus Mortonia 23:665 Genus Morus 28:200 Genus Ononis 30:138 resorcinolic from 30:138 Genus Pseudomonas 29:329 Genus Tanacetum 27:547 Genus Teucrium 23:591-648 biological evaluation of 23:591648 chemical evaluation of 23:591-648 Geodia 25:768;26:488,1210 Geodia cydonium 25:718 Geothelphusa dehaai 19:647 Geothricum penicillatum 13:302 Geotrichum candidum 23:349;26:673 Geotrichum louberi 26:673 Geotrichum penicillatum 25:129 Geranii 27:413 corilagin from 27:413 Geranii herba 27:415 Geranium 29:572 Geranium macrorhizum 5:679 Geranium thunbergii 17:421,428,433 27:413 Gerinimum genera 27:755 Geumjaponicum 23:397;29:574 Giardia intestinalis 26:1063 Gibberella cyanea 25:162,166
1278
Gibberella fujikuroi 24:938,942,954 diterpenes from 24:938 gibberellins from 24:938 Gibberella fujikuroi 8:115,117; 25.253,255 Gibberella gaminis var. avenae 25:304, 305,306,308,310 Gibberella pluicaris 25:293,305,307,311, 317,319 Gibbonsia elegans 17:94;25:787 Giffordia mitchelae 21:306 Gigartina skottsbergii 30:402 carrageenans from 30:402 Ginkgo biloba L. 9:317,321,323,659,660; 21:591 ;24:297 ;26:929;28:165,170; 29:571 3 '-O-methylmyricetin-3-Orutinoside from 28:167 5'-methoxybilobetin from 28:166 amentoflavone from 28:166 apigenin from 28:167 Ginseng rubra 21:675 ginsenosides from 21:675 Gissampelos insularis 25:478 Glaucium genera 27:163 Gleditsiajaponica 15:195;21:643; 24:241,243,246 saponin C from 21:643 Gleditsia macracantha 26:1140 Gleditsia saponins 15:191 Gleditsia triacanthos 26:1115,1116,1139, 1143 Gleichenia japonica 25:251,276 Gleosporium fructigenum 18:715 Gliocadium virens 21:238 Gliocadium virens deliquescens 21:238 Gliocadium virens fimbriatum 21:238 Gliocladium deliquescens 21:225 gliodeliquescins from 21:225 viridol from 21:238 Gliocladium fimbriatum 21:182,218 viridol from 21:238 Gliocladium flavofuscum 21:238 Gliocladium fujikuroi 21:227 Gliocladium sp. 5:370;21:198,203, 215,224,227,235,237,238 gliocladins A-C from 21:235
Gliocladium vermoesenii 21:207 nectriapyron from 21:207 vermopyrone from 21:207 Gliocladium virens 21:218,229,232,239 viridin from 21:238 viridol from 21:238 Globodera 26:429,432,467,471 Globodera pallida 26:229,474 Globodera rostochiensis 26:229,430,461, 474,477,486,487 Gloemerella cingulata 25:64,166-168 Gloeoplyllum sepiarium 23:354 Gloeosporium lacticolor 15:351 Glomerella cingulata 23:112,115 extracellular polysaccharide of 23:112 Glomerella cingulata 29:5905:278,415, 228,230,240 Glomerella fructigene 9:230,239 Glomerella glycines 9:230,239 Glomerella gossypii 9:230,239 Glomerella sp. 9:228,230,239 Glomerella tucumanensis 9:230,239 Gloria superba 5:47 Glossina spp. 26:785 Glossodoris quadricolor 28:650 latrunculin B from 28:650 Glossostemon bruguieri 28:425 Gluta renghas 9:319 Glycine max 15:196;25:93,105,669; 26:930;29:578,581,593,595,604, soyasaponin A3 15:196 Glycine soya 25:93,101 Glycosmic cyanocarpa 23:343 Glycosmis bilocularis 13:348,350,355 Glycosmis citrifolia 13:348,349,361 cycloglycofoline from 13:348,349 glycocitrine I from 13:348,350 glycofoline from 13:348,349,361 pyranofoline from 13:348,350 Glycoxylon huberi 15:31 Glycyphylla smilax 15:31 Glycyrrhiza aspera 28:204 Glycyrrhiza eurycarpa 28:204 Glycyrrhiza glabra 15:5;21:742;22:96, 422;24:151,275,919;25:465,476; 26:800;27:6,15,29 ;28:204,206,234, 239;29:589
1279 8-(?,?-dimethyallyl)-wighteone from 28:206 3 '- (?,?-dimethylallyl)-kievitone from 28:206 edudiol (3,9-dihydroxy- 1me tho xy- 2-pren ylpteroc arpan) from 28:206 euchrenone from 28:206 flavanone from 28:239 gancaonin G from 28:206 gancaonin H from 28:206 glabrene from 28:206 glabridin from 28:206 glabrone from 28:206 glisoflavanone from 28:206 glyasperin A from 28:206 glyasperin C from 28:206 glyasperin D from 28:206 glycyrrhizic acid from 28:239 glycyrrhizin from 27:6,15,29 glyinflanin G from 28:206 glyinflanin K from 28:206 hispaglabridin A from 28:206 3-hydroxyglabrol from 28:206 3-hydroxyparatocarpin C from 28:206 isoderone semilicoisoflavone B from 28:206 kanzonol U from 28:206 kanzonol V from 28:206 kanzonol W from 28:206 kanzonol X from 28:206 kanzonol Y from 28:206 kanzonol Z from 28:206 licorice-saponin G2 from 28:239 liquiritigenin from 28:239 medicarpin from 28:206 1-methoxyphaseollidin from 28:206 4'-O-methylglabridin from 28:206 shinpterocarpin from 28:206 uses as licorice 28:204 Glycyrrhiza inflata 15:26;21:740;27:15, 29,30,425;28:204 apioglycyrrhizin from 27:15,29,30 araboglycyrrhizin from 27:15, 29,30 Glycyrrhiza korshinskyi 28:204 Glycyrrhiza pallidiflora 28:234
Glycyrrhiza sp. 21:740,742;28:199,226; 519 bioactive phenolic compounds from 28:223 Glycyrrhiza uralensis 21:740;28:204,234, 242;29:771 4'-O-methylglabridin from 28:242 1-methoxyphaseollidin from 28:242 3-O-methylglycyrol from 28:242 6,8-diprenylorobol from 28:242 dihydroisoflavone A from 28:242 gancaonin I from 28:242 gancaonol C from 28:242 gancaonol from 28:242 glycyrin from 28:242 hispaglabridin A from 28:242 isoglycyrol from 28:242 isolicoflavonol from 28:242 licoricone from 28:242 shinflavanone from 28:242 vestitol from 28:242 Glyptopetalum sclerocarpum 30:656,668, 670
20-hdroxy-22-oxo-20-epitingenone from 30:670 20-hydroxy-22-oxotingenone from 30:670 21 c~-hydroxy-20,22-dioxo30(20(21)abeo-21desoxotingenone from 30:670 glyptopetolide from 30:656 Gmelina arborea 17:332 Gnathotricus retusus 25:143 Gnathotricus sp. 25:143 Gnathotricus sulcatus 25:143 Gnetaceae spp. 27:766 Gnetum parvifolium 26:530 Gnetum ula 9:258,263 Gnoderma applantum 25:131 Gobius criniger 18:48 Gomophia watsoni 15:61 Goniothalamas giganteus 19:498 Goniothalamus giganteus 9:393,395; 18:221,222 Goniothalamus sesquipedalis 9:393 Gonomia kamassi 1:124 Gonvaulax polyedra 25:845 Gonyaulax tamarensis 17:4
1280
Gonystylus keithii 19:764 Gorgonia flabellum 9:37 23-demethylgorgosterol from 9:37
Gorgonia ventilina 9:37
23-demthylgorgosterol from 9:37
Goriolus veJ~'icolor 23:132 Gorytes campestris 5:251 Gorytes mystaceu 5:251 Gossypium herbaceum L. 22:521;27:855; 29:579 for epilepsy 22:522 Gossypium hirsutum 26:463;29:586 Gossypium indicum 29:572 Gossypium sp. 29:581 Gpysophila paniculata 24:154 Gracilaria 25:769 Gracilaria coronopifolia 25:729 Gracilaria edulis 19:570 Gracilaria verrucosa 19:571 Gracula religiosa 5:837 Graphium sp. $:307,309,325 Grapholitha molesta 6:557;15:384 Guidongnin 15:142,150,159,174 13C-nmr of 15:159 from Rabdosia rubescens 15:174 ~H-nmr of 15:150 Graphosoma italicum 22:387 Grateloupia filicina 25:862 Grevillea banskii 9:319,320 Grevillea hilliana 9:320 Grevillea pteridifolia 9:320 Grevillea pyramidalis 9:319,354 Grevillea robusta 9:320;26:1157;27:839 extract of 27:839 Grevillea sp. 9:329 Grifola frondosa $:287;23:115,124,133 Grifola umberllata $:287,317 Grindalia haverrdii 25:252 Grindella sp. 25:251 Gromphadorhina portentosa 9:488,489 Gryllus bimaculatus 9:492;29:6 Gryllus domesticus 22:387 Guaiacum officinale 5:197,139,319, 324;9:51-59 Guayabillo 22:559 Guettarda platypada 17:116,125 Gum japonica 29:575 Gundelia toumefortii 7:427 Gutierrezia grandis 5:680;25:251
Gutierrezia microcephala $:680,681 Gutierrezia spathulata 25:251 Gutierrezia sphacrocephala 25:251 Gutierrezia texana 5:679 Gutierrezia-xanthocephahum 5:676 Guttiferae 7:409-411,417,418,420-423, 19:768
Gym.galatheanum 6:76,135 Gyminda 18:741 Gymnema alternifolium 27:41,43,44 alternoside I-V from 27:41
Gymnema sylvestre 15:36;18:649,650, 653,661,671,673 ;21:666,674 ;23:519;2 7:40-43,48,49 gymnemasoponin III,IV,V from 27:41 gymnemic acid II VI,VIII-XVIII from 27:41 Gymnocladus chinensis 21:643 saponin D from 21:643 Gymnocolea inflata 2:280 Gymnocrinus richeri 28:719 gymnochrome C from 28:719 Gymnodinium breve 17:20;19:430; 21:300,301 Gymnomitrion obtusum 13:39 Gymnosperma glutinosum 5:679-681 Gymnosporia montana 23:656 Gymnotroches axillaris 7:192 Gynandropsis gynandra (L.) 28:395,405 repellent properties of 28:395 Gynandropsis pentaphylla 22:522 for convulsions 22:522
Gynostemma pentaphyllum 18:662;21:675 ;24:144 ;27:15,28 gypenoside XX from 27:15 Gypsophila arrostii 26:38,39,40 Gypsophila bermejoi 26:44,52 Gypsophila capillaris 26:42,43 Gypsophila capitala 26:44 Gypsophila fastigiata 26:38 Gypsophila oldhamiana 26:41 Gypsophila paniculata 26:38-40,42,53 Gypsophila perfoliata 26:38 Gypsophila saponins 26:55 Gypsophila sp 24:131,144,149,155,161; 26:55 Gyrocarpus americanus 22:522
1281
Gyrocarpus americanus Jacq. 22:552 for epilepsy 22:522 Gyrophora aureolum 6:135 Gyrophora esculenta 5:311,322;23:123 Gyrostroma missouriense 15:351,383 nectriapyrone from 21:207 Hacelia attenuata 7:290,295,304-306,61; 15:61 Haemaphysalis intermedia 28:400 Haematococcus pluvialis 21:305 Haematoxylon campechainum 15:34, 20:776;27:18 hematoxylin from 27:18 Haemodoraceae 17:372 Haemonchus 26:425 Haemonchus contortus 22:401;25:794; 26:429,431,432,440,446,451,453,457,4 70,482,484,488,490,491 Haemonchus contortus 28:342,349 Haemophilus influenzae 4:195;25:781 Hakea 26:1157 Hakea amplexicaulis 9:320 Hakea gibbosa 29:576 Hakea persihana 9:320 Hakea trifurcata 9:320 Halcyon smyrnensis 5:837 Halichondria cf. moorei 28:698 Halichondria cylindrata 23:341 ;28:139; 680 Halichondria 27:875;28:658 Halichondriajaponica 18:475;25:718 Halichondria melanodocia 5:387 Halichondria okadai 5:378,379,383,384; 21:411;25:799 Halichondria panicea 17:719;25:852; 28:661 Halichondria sp. 17:17;21:329,330; 25:716,847,848,852,854 ;28:659,660 diterpenoid from 28:659 from Marshall islands 28:660 guai-6-ene skeleton of 28:660 sesqui- and diterpenoids from 28:659 sesquiterpenoid from 28:659 Halichondria sponge 21:252;28:663 isothiocyanates from 28:663 Halichondrida order 28:658
Halichondriidae family 28:671 Haliclona exigua 21:267 Haliclona nigra 28:684 from Papua New Guinea 28:684 haligramides A of 28:684 Haliclona rubens 21:308 Haliclona sp. 5:346,347,459;21:260,674, 706;25:694,695,709,710,725,728; 28:706 haliclostanone sulfate from 28:706 Halicona kormella 25:722 Halimeda incrassata 18:689 Halimeda tuna 689 Haliotis discus hannai 25:788 Halityle regularis 7:297;15:61 halityloside D and I from 15:61 gomophioside A from 15:61 halitylosides A,B,D,E,F,H,I from 7:297 Halobacterium sp. 7:355 bacterioruberin from 7:355 Halocynthia papillosa 28:642 6-methylheptyl sulfate from 28:642 (E)-oct-5-enyl sulfate from 28:642 Halocynthia roretzi 6:152;23:243;25:704, 784;28:642 halocynthiaxanthin from 6:152 mytiloxanthinone from 6:152 Halopappus parvifolus 25:255 Halopappus sp. 25:251 Halymenia porphyroides 9:85,86,88 marine N-acylsphingosine from 9:85,86,88 Hamamelis virginiana 21:543;29:588 Hamigera tarangaensis 25:803 Haminaea templadoi 26:90 Hamioea cymbalum 25:787 Hamycin 26:794,795 Hanacantha sp. 25:705 Hannoa klaineana 18:726;23:302 Hannoa quassiaundulata 26:466 Hanseniaspora osmophila 5:283 Hansenula beijerinkii 5:287 Hansenula bimundalis var. americana 5:287 Hansenula capsulata 5:280,284,315 Hansenula ciferii 5:287 Hansenula fabianii 5:287
1282
Hansenula minuta 5:315 Hansenula mrakii 5:287;25:129 Hansenula polymorpha 22:601 ;26:1263, 1267,1270,1272,1274
Hansenula saturnus 5:287 Hansenula sp. 5:281,282,315;26:1087 mannans from 5:282
Hansenula subpelliculosa 5:282 Hansenula wingei 5:282 Hapalochlaena maculosa 18:724 Hapalopilus nidulans 29:265 Hapalopilus rutilans 29:265 Hapalosiphon fontinalis 11:278;21:362; 26:363 hapalindoles from 11:278 Hapalosiphon intricatus 26:363 Haplopappus 29:577 Haplopappus canescens 29:577,580, 581 Haplophyllum dauricum 17:335 Haplophyllum dubium 22:522 Haplophyllum glabruinum 22:522 Haplophyllum hispanicum 26:263 diphyllin acetyl apioside from 26:263 tuberculatin from 26:263 Haplophyllum perforatum 22:522 Happlopappus arbutoides 25:251 Happlopappus pulchellus 25:251 Hasnenula holstii 5:280,285,315 Haticondria cylindrata 25:867 Hedeomapulegioides L. 22:522 for convulsions and spasms 22:522 Hedera helix 7:427,20:6;21:642,662, 674 ;24:132,133 ;26:813 ;29:586 Hedychium 23:837 Hedychium coronarium 23:836;24:284; 25:265 Hedychium flavum 27:377
Heinsia crinata 151 Heisteria pallida 22:360 Helenium 26:436 Helenium amarum 20:10 Helenium microce 20:10 Helianthus 29:589 Helianthus annuum 21:634,660;25:391, 670;29:593,593,600
Helianthus occidentalis 251
Heliathus annuus L. 19:247 Helicacus kanaloanus 15:383 Helichrysum gymnocephalum 27:377 Helichrysum nitens 5:413 antifungal flavonoids from 5:651
Helichrysum picardii 29:702 Helichrysum rupestre 25:259 Helichrysum setosum 22:522 for epilepsy 22:522
Helicobacter pylori 13:183;22:432; 25:611,617,618,778;26:693;30:338 effect ofchrysophanol 30:338 effect of emodin 30:338 effect ofrhein 30:338 Helicondria sp. 9:37 petrosterol from 9:37 Heliconius pachinus 8:222 macrolide from 8:222 Helicostylium piriforme 25:317 Helicoverpa zea 26:697;29:292 Helicteres isora 26:226 helisorin from 26:226 helisterculin A&B from 26:226 Heliocidaris erythrogramma 17:95 Heliopsis buphthalmoides 17:319 Heliopsis helianthoide 5:728,334 hemoglobin components of 5:836839 in bird species 5:836-839 Heliopsis longipes 7:427;24:689 Heliothis armigera 23:66;26:850,851 Heliothis virescens 7:395;21:252; 25:768;26:439,485 Heliotropium bovei 26:874 Heliotropium floridum 26:874 Heliotropium megalantum 26:874 Heliotropium sinuatum 26:874 Heliotropium sp. 26:872 Heliotropium strygosum 19:145 Heliotropium. 19:145 Helix promatia 18:655;19:636; 25:210;27:468 Helleborus purpurascens 21:657 Helminthosporin teres 2:434 Helminthosporium carbonum 22:459; 27:498,499 Helminthosporium gramieu 26:1210 Helminthosporium oryzae 9:237
1283
Helminthosporium sativum 4:23,24; 24:192 Helminthosporium sigmoideum 22:273 Helvella gyomitra 9:203 Hemicentrotus pulcherrimus 26:1188; 28:717;29:268 Hemidesma indicus 22:522 Hemidesmus indicus R. 22:522 for epilepsy and nocturnal epilepsy 22:522 Hemophilus influenzae 13:162,177,181 Hemsleya carnosiflora 24:249;27:14; 29:53 carnosifloside V from 27:14 carnosifloside VI from 27:14 structure of 27:26 Hemsleya panacisscandens 24:249; 27:15,25 scandenoside R6 from 27:15,25 scandenoside R11 from 27:15,25 Henricia laeviuscola 15:48,55;28:718 henricioside from 15:48,55 Heracleum L. 21:615 Heracleum sibiricum 22:522 Heracleum verticillatum 22:522 Herdmania cmwata 21:366 Heritiera littoralis 7:176,177,180,181, 185,187,190 Hernandia 30:559-561,563-580 benzenoids from 30:562 bioactive constituents of 30:559 biological studies of 30:561 classification of 30:560 division of 30:560 economic applications of 30:559 ethnobotanical studies of 30:561 family 30:560 flavonoids from 30:562 genus 30:560 hernandiaceae family of 30:559 isoindole from 30:562 isoquinoline alkaloids from 30:560,562 lignans from 30:560,562 monoterpenoids from 30:562 pyridine from 30:562 species of 30:559 sterols from 30:562
subclass of 30:560 subfamily of 30:560 Hernandia albiflora 30:560 (-)-laetine from 30:564 (+)-actinodaphnine from 30:563 (+)-corytuberine from 30:563 (+)-hernagine from 30:563 (+)-hernandaline from 30:563 (+)-hernovine from 30:564 (+)-isoboldine from 30:564 (+)-isocorydine from 30:564 (+)-laurotetanine from 30:564 (+)-magnoflorine from 30:564 (+)-N-formyldehydroovigerine from 30:563 (+)-N-formylnornantenine from 30:563 (+)-N- formylovigerine from 30:563 (+)-N-hydroxyhernangerine fi-om 30:564 (+)-N-methyl-6,7-dimethoxyisoquinolone from 30:564 (+)-N-methylactinodaphnine from 30:564 5,6- Dime thoxy-N- me th ylphthalimide from 30:563 6,7-dimethoxy-N-methylisoquinoline from 30:563 7-formyldehydrohernangerine from 30:563 7-formyldehydronornantenine from 30:563 7-formyldehydroovigerine fiom 30:563 7-hydroxy-6-methoxy- 1methylisoquinoline from 30:564 atheroline from 30:563 backebergine from 30:563 dehydrohernandaline 30:563 demethylsonodione from 30:563 hernandonine from 30:564 hernangerine from 30:564 hernanymphine from 30:564 laetanine from 30:564 laudanosine from 30:564 lindearpine from 30:564 monoterpene from 30:569 N-(N-methylcarbamoyl)-O-
1284
methylbulbocapnine from 30:564 N-formylnornantenine from 30:563 N-hydroxyovigerine from 30:564 N-methylcorydaldine from 30:564 sterols from 30:569 Hernandia albiflora sp. 30:560 Hernandia beninensis sp. 30:560 Hernandia bivalves sp. 30:560 Hernandia catalpifolia sp. 30:560 Hernandia cordigera 5:485,561 ;30:562566,568,569 (-)-yatein from 30:569 (+)-actinodaphnine from 30:563 (+)-hemagine from 30:563 (+)-isoboldine from 30:564 (+)-isocorydine from 30:564 (+)-laurotetanine from 30:564 (+)-nandigerine (hernangerine) from 30:565 (+)-neolitsine from 30:565 (+)-N-methylactinodaphnine from 30:564 (+)-N-methyllaurotetanine from 30:565 (+)-norisocorydine from 30:565 (+)-nomantenine from 30:565 (+)-ovigerine from 30:565 (+)-reticuline (S)-reticuline from 30:566 5'-methoxypodorhizol from 18:561;30:569 5'-methoxyyatein from 30:569 anthricin from 30:568 bursehernin from 30:568 cordigerin from 30:568 hernandin from 30:569 podorhizol from 30:569 Hernandia cubensis sp. 30:560 Hernandia didymantha sp. 30:560 Hernandia drakeana sp. 30:560 Hernandia guianensis 30:562-566,56857O (+)-actinodaphnine from 30:563 (+)-hemovine from 30:564 (+)-laurotetanine from 30:564 (+)-nandigerine (hernangerine) from 30:565 (+)-ovigerine from 30:565
(+)-reticuline from 30:566 acetylpodophyllotoxin from 30:568 anthricin from 30:568 bursehernin from 30:568 N-methylhemovine from 30:565 N-methylnandigerine from 30:565 picropodophyllin from 30:569 podorhizol from 30:569 stigmasterol from 30:570 [3-sitosterol from 30:570 Hernandia guianensis sp. 30:560 Hernandiajamaicensis sp. 30:560 Hernandia mascarenensis sp. 30:560 Hernandia moerenhoutiana 30:561,597 antimalarial activity of 30:561 antioxidant activity of 30:561 biological activities of 30:562 cytotoxic activity of 30:561 spasmolytic activity of 30:561 to retain placenta 30:561 to treat malaria 30:561 use in morning sickness 30:561 use in postpartum hemorrhage 30:561 use in treament of malaria 30:597 use in treament of morning sickness 30:597 use in treament of postpartum hemorrhage 30:597 Hernandia moerenhoutiana sp. 30:560 Hernandia nukuhivensis sp. 30:560 Hernandia nymphaeifolia 26:212; 30:561,563-570,597 (-)-6'-hydroxyyatein from 30:569 (-)-deoxypodophyllotoxin from 26:218;30:568 (-)-hemone from 30:569 (-)-nymphone from 30:569 (-)-yatein from 30:569 (+)-epiaschantin from 26:218; 30:568 (+)-epimagnolin from 26:218; 30:568 (+)-epiyangambin from 26:218; 30:568 (+)-hemovine from 30:564 (+)-isocorydine from 30:564 (+)-laurotetanine from 30:564
1285 (+)-magnoflorine from 30:564 (+)-nandigerine (hemangerine) from 30:565 (+)-N-hydroxyhemangerine from 30:564 (+)-N-methyllaurotetanine from 30:565 (+)-N-methylovigerine from 30:565 (+)-nomantenine from 30:565 (+)-ovigerine from 30:565 (+)-thalicarpine from 30:567 (+)-vateamine-2 ' [~-N-oxide from 30:567 3-cyano-4-methoxypyridine from 30:567 3 [3-hydroxystigmast-5,22-dien-7one from 30:569 3 [3-hydroxystigmast-5-en-7-one from 30:570 5,6-Dimethoxy-N-methylphthalimide from 30:563 5'-methoxypodorhizol from 30:569 6ot-hydroxystigmast-4,22-dien-3one from 30:570 6(z-hydroxystigmast-4-en-3-one from 30:570 7-formyldehydrohernangerine from 30:563 7-formyldehydronornantenine from 30:563 7-formyldehydroovigerine from 30:563 7-hydroxy-6-methoxy- 1methylisoquinoline from 30:564 7-oxohernagine from 30:565 7-oxohernangerine from 30:565 atheroline from 30:563 biological activities of 30:562 dehydrohemandaline from 30:563 hernandial from 30:567 hernandonine from 30:564 hemanymphine from 30:564 N-(N-methylcarbamoyl)-Omethylbulbocapnine from 30:564 N-hydroxyovigerine from 30:564 N-methylcorydaldine from 30:564 N-methylhernovine from 30:565
northalifoline from 30:565 nymphaeol A from 30:567 nymphaeol B from 30:567 nymphaeol C from 30:567 ovigeridimerine from 30:566 ovihernangerine from 30:566 oviisocorydine from 30:567 oxohernandaline from 30:565 oxonantenine from 30:566 stigmasta-4,22-dien-3-one from 30:570 thalifoline from 30:566 to retain placenta 30:561 to treat malaria 30:561,597 use in morning sickness 30:561 use in postpartum hemorrhage 30:561,597 use in treament of morning sickness 30:597 [~-sitosterone from 30:570 (-)-yatein from 26:218 (-)-6'-hydroxyyatein from 30:569 (-)-deoxypodophyllotoxin from 30:568 (-)-hernone from 30:569 (-)-nymphone from 30:569 (-)-yatein from 30:569 (+)-epiaschantin from 30:568 (+)-epimagnolin from 30:568 (+)-epiyangambin from 30:569 (+)-hernovine from 30:564 (+)-isocorydine from 30:564 (+)-laurotetanine from 30:564 (+)-magnoflorine from 30:564 (+)-nandigerine (hernangerine) from 30:565 (+)-N-hydroxyhernangerine from 30:564 (+)-N-methyllaurotetanine from 30:565 (+)-N-methylovigerine from 30:565 (+)-nornantenine from 30:565 (+)-ovigerine from 30:565 (+)-thalicarpine from 30:567 (+)-vateamine-2 ' [3-N-oxide from 30:567 3-cyano-4-methoxypyridine from 30:567
1286 313-hydroxystigmast-5,22-dien-7one from 30:569 3 ~-hydroxystigmast-5-en-7-one from 30:570 5,6-dimethoxy-N-methylphthalimide from 30:563 5'-methoxypodorhizol from 30:569 6c~-hydroxystigmast-4,22-dien-3one from 30:570 6c~-hydroxystigmast-4-en-3-one from 30:570 7-formyldehydrohernangerine from 30:563 7-formyldehydronornantenine from 30:563 7- formyldehydroovigerine from 30:563 7-hydroxy-6-methoxy- 1methylisoquinoline from 30:564 7-oxohernagine from 30:565 7-oxohernangerine from 30:565 atheroline from 30:563 dehydrohernandaline from 30:563 hernandial from 30:567 hernandonine from 30:564 hernanymphine from 30:564 N-(N-methylcarbamoyl)-Omethylbulbocapnine from 30:564 N-hydroxyovigerine from 30:564 N-methylcorydaldine from 30:564 N-methylhernovine from 30:565 northalifoline from 30:565 nymphaeol A from 30:567 nymphaeol B from 30:567 nymphaeol C from 30:567 ovigeridimerine from 30:566 ovihernangerine from 30:566 oviisocorydine from 30:567 oxohernandaline from 30:565 oxonantenine from 30:566 stigmasta-4,22-dien-3-one from 30:570 thalifoline from 30:566 [3-sitosterone from 30:570 Hernandia obovata sp. 30:561 Hernandia olivacea sp. 30:561
Hernandia ovigera 5:485;30:563-569 (-)-deoxypodophyllotoxin from 30:568 (-)-dimethylmataire sinol from 30:568 (-)-yatein from 30:569 (+)-epimagnolin A from 30:568 (+)-epimagnolin from 30:568 (+)-epiyangambin from 30:569 (+)-nandigerine (hernangerine) from 30:565 (+)-ovigerine from 30:565 (+)-thalicarpine from 30:567 (7R,SS,7'R,8'R)-(+)-7'-acetyl-5 'methoxypicropodophyllin from 30:567 (7R,8S,7'R,8'R)-(+)-7'-acetylpicropodophyllin from 30:568 1,2,3,4-dehydrodeoxypo dophyllotoxin from 30:568 1,2,3,4-dehydropodophyllotoxin from 30:568 5'-methoxypodorhizol from 30:569 5'-methoxyyatein from 30:569 6,7-demethylenedeoxypodophyllotoxin from 30:568 6,7-dimethoxy-N-methylisoquinoline from 30:563 anthricin from 30:568 bursehernin from 30:568 caruilignan C from 30:568 dehydrothalicarpine from 30:566 deoxypicropodophyllin from 30:568 desoxypicropodophyllin from 18:600 diasesartemin from 30:568 diayangambin from 30:568 epiaschantin from 18:600 epimagnolin from 18:600 hernandin from 30:569 hernandonine from 18:600;30:564 hernolactone from 30:569 isohernandion from 18:600 N-methylcorydaldine from 30:564 oxocrebanine from 30:565 oxothalicarpine from 30:567 p-hydroquinone from 30:567
1287 podophyllotoxin from 30:569 podorhizol from 30:569 Hernandia ovigera var. mascarenensis 30:562-565,568,569 (-)-yatein from 30:569 (+)-actinodaphnine from 30:563 (+)-epimagnolin from 30:568 (+)-hernagine from 30:563 (+)-hernovine from 30:564 (+)-nandigerine (hernangerine) from 30:565 bursehernin from 30:568 hernandonine from 30:564 N-methylnandigerine from 30:565 Hernandia peltata 20:522;30:562, 564,566-569 (-)-laetine from 30:564 (-)-yatein from 30:569 (+)-6-northalicarpine from 30:566 (+)-ambrimine from 30:566 (+)-efatine from 30:566 (+)-epiaschantin from 30:568 (+)-epimagnolin from 30:568 (+)-epiyangambin from 30:569 (+)-hebridamine from 30:566 (+)-malekulatine from 30:566 (+)-reticuline (S)-reticuline from 30:566 (+)-thalicarpine from 30:567 (+)-thalicarpine-2 '-N-oxide from 30:567 (+)-thalmelatine from 30:567 (+)-vanuatine from 30:567 (+)-vilaportine from 30:567 6c~,7-dehydrothalmelatine from 30:566 bursehernin from 30:568 epieudesmin from 30:568 vateamine from 30:567 Hernandia rostrata sp. 30:561 Hernandia sonora 30:562-569 (+)-corytuberine from 30:563 (+)-hernagine from 30:563 (+)-hernandaline from 30:563 (+)-malekulatine from 30:566 (+)-N-formyldehydroovigerine from 30:563 ( +)-N- formylnornantenine from 30:563
(+)-N-formylovigerine from 30:563 (+)-N-methyl-6,7-dime tho xyisoquinolone from 30:564 (+)-ovigerine from 30:565 5'-methoxypodorhizol acetate from 30:569 5-methoxypodophylloton acetate from 30:569 5-methoxypodophyllotoxin from 30:569 acetylpodophyllotoxin from 30:568 anthricin from 30:568 atheroline from 30:563 backebergine from 30:563 dehydrohernandaline from 30:563 demethylsonodione from 30:563 hernandin from 30:569 hernandonine from 30:564 hernangerine from 30:564 isovanillin from 30:567 N-formylnornantenine from 30:563 N-methylhernangerine from 30:565 norsonodione from 30:565 picropodophyllin from 30:569 podophyllotoxin from 30:569 sonodione from 30:566 Hernandia sp. 30:561,562,588, 589,594,597 (-)-deoxypodophyllotoxin from 30:595 (-)-hernone from 30:595 (-)-yatein from 30:595 (+)-epiaschantin from 30:595 (+)-epimagnolin from 30:595 (+)-epiyangambin from 30:595 (+)-hernandaline from 30:594 (+)-laurotetanine from 30:594 (+)-malekulatine from 30:594 (+)-ovigerine from 30:594 (+)-reticuline from 30:595 (+)-thalicarpine from 30:595 (+)-vateamine-2' [3-N-oxide 30:595 7-oxohernagine from 30:595 activity in antiplatelet aggregation turbidimetry assay 30:594
1288 activity in human murine cancer cell line 30:589 activity in human tumor xenograft system 30:589 activity in mouse model 30:589 antimalarial activities of 30:588 antioxidant activity of 30:597 antiplatelet aggregation activity of 30:588 anti-tumor activity of 30:589 benzenoids from 30:562 biological activities of 30:562 cancer chemopreventive activity of 30:588 constituents of 30:562 cytotoxic activity of 30:588, 589,597 dehydrohernandaline from 30:594 flavonoids from 30:562 hernangerine from 30:594 in vitro 30:588 in vivo 30:589 inhibitory effects of 30:594 isoindole from 30:562 isolates from 30:594 isoquinoline alkaloids from 30:562 isovanillin from 30:594 lignans from 30:562 monoterpenoids from 30:562 N-methylhernangerine from 30:594 phytochemical studies of 30:597 pyridine from 30:562 role in morning sickness 30:561 role in placenta 30:561 role in postpartum hemorrhage 30:561 spasmodic activity of 30:597 sterols from 30:562 structures of 30:597 to treat malaria 30:561 Hernandia stenura sp. 30:561 Hernandia stokesii sp. 30:561 Hernandia tahitensis sp. 30:561 Hernandia temarii sp. 30:561 Hernandia voyronii 30:561,562,564-566, 569,597 (-)-laetine from 30:564 (-)-pallidine from 30:566
(-)-pallidine from 30:566 (-)-yatein from 30:569 (+)-6-northalicarpine from 30:566 (+)-ambrimine from 30:566 (+)-efatine from 30:566 (+)-epiaschantin from 30:568 (+)-epimagnolin from 30:568 (+)-epiyangambin from 30:569 (+)-hebridamine from 30:566 (+)-malekulatine from 30:566 (+)-N-methyllaurotetanine from 30:565 (+)-norisocorydine from 30:565 (+)-perillaldehyde from 30:569 (+)-reticuline from 30:566 (+)-thalicarpine from 30:567 (+)-thalicarpine-2 '-N-oxide from 30:567 (+)-thalmelatine from 30:567 (+)-vanuatine from 30:567 (+)-vilaportine from 30:567 6ot,7-dehydrothalmelatine from 30:566 antimalarial activity of 30:561 antioxidant activity of 30:561 biological activities of 30:562 bursehernin from 30:568 cytotoxic activity of 30:561 epieudesmin from 30:568 herveline A from 30:566 herveline I3 from 30:566 herveline C from 30:566 herveline D from 30:566 laetanine from 30:564 laudanosine from 30:564 lindearpine from 30:564 norpredicentrine from 30:565 ocobotrine from 30:565 spasmolytic activity of 30:561 to retain placenta 30:561 to treat malaria 30:561 use in morning sickness 30:561 use in postpartum hemorrhage 30:561 use in treament of malaria 30:597 use in treament of morning sickness 30:597 use in treament of postpartum
1289
hemorrhage 30:597 vateamine from 30:567 Hernandiaceae 18:558 Herniaria fontanesii 26:52,54 Herniaria glabra 26:50,51 Herniaria hirsuta 26:50 in arrthritis 26:50 in infections of urinary & respiratory tracts 26:50 in kidney disorders 26:50 in neural catarrh 26:50 in neuritis 26:50 in purifying the blood 26:50 in rheumatism 26:50 Herniaria saponins A-D 26:50-52 Helpes simplex virus 5:418;12:366; 21:150,252;25:121,779,782,815,891, 948; 26:223;27:257 Herpestis monniera 22:513 for epilepsy and nocturnal epilepsy 22:513 Herpestis monniera 22:522 Herpetomonas curzi 2:298 Herpetomonas mmuscarum 2:298,301 Herpetomonas samuelpessoai 2:298; 26:138 polysaccharides in 2:299-301 Hesperethusa crenulata 22:522 for epilepsy 22:522 Hesperiphona vespertina 5:836;8:151, 152;9:152 hemoglobin components of 5:836 of (x-cedrene 5:790 of artemisinin 5:25,26 of angelic acid 5:778 oftiglic acid 5:778 of 7-hydroxyfrullanolide 9:152 spectra of 8:151,152 Heterakis spurnosa 26:482 Heterobasidion annosum 21:212 Heterocentron roseum 23:404,405 Heterodera 26:429,432 Heterodera cajani 26:469 Heterodera glycines 26:429,454,456,466, 467,473,477 Heterodera rostochiensis 26:437 Heterodera schuchiti 26:481 Heteromorpha trifoliata 7:415;21:600; 22:97; 23:341
Heteronema 6:23 halopuupehenones from 6:23 puupehenones from 6:23 Heteropappus altaicus 21:634,660 Heteropappus biennis 21:660 Heteropora alaskensis 17:90,92 Heteropsylla cubana 21:595 Heteropyxis natalensis 21:599 Heterorhahditis nematodes 26:471 Heterotropa takaoi 17:348 Heteroxenia fuscescens 21:282 Hexabranchus sanguineus 17:16,19:609 Heynea trijuga 2:267 Hibiscus abelmoschus L. 22:522 for hysteria 22:522 Hibiscus rosa-chinensis 7:180,183,195 Hibiscus rosa-sinensis 28:400 Hibiscus tiliaceus 7:185 Hibiscus vitifolis 29:572 Himerometra robustipinna 7:266 Hincksinoflustra denticulata 17:85,88 Hippeastrum sp. 26:614 Hippeastrum vittatum 22:522 Hippocratea 18:741,754 Hippocratea indica 5:749 Hippocratea volubilis 30:661,646 lupane caffeoyl esters from 30:646 volubilide from 30:661 Hippocrepis balearica 19:117 Hippocrepis comosa 117 Hippodiplosia insculpm 17:90,92 Hippospongia metachromia 5:430 Hippospongia sp. 5:432;25:698,721, 871;28:690 Hiptagamadablota 19:117 Hiptage benghalensis 22:522 for epileptic fits 22:522 Histiopteris incisa 26:122 Histoplasma capsulatum 5:307; 22:57,248;23:382 Histoplasma duboisii 5:307 Histoplasma farcinosum 5:307 Histoplasma sp. 5:325,328 Holarrhena floribunda 22:523 Holarrhena sp. 26:837 Holothuria atra 7:269 holothurin A from 7:269 holothurin B from 7:269 holothurin B~ from 7:269
1290
Holothuria edulis 7:269 holothurin A2 from 7:269 Holothuria floridana 7:269 holothurin A~ from 7:269 holothurin A2 from 7:269 holothurin B~ from 7:269 Holothuria floridea 21:315 Holothuria forskali 28:592 Holothuria grisea 7:269 holothurin A~ from 7:269 Holothuria leucospilota 7:268 holothurin A from 7:268 holothurin B from 7:268 holothurin from 7:268 Holothuria leucospilota 15:87 Holothuria lubrica 7:269 holothurin A from 7:269 holothurin B from 7:269 Holothuria mexicana 7:281;26:72 Holothuria pervicax 15:92;28:720 ganglioside HPG-8 from 28:720 Holothuria scabra 7:270 Holothuria squamiera 7:269 holothurin A from 7:269 holothurin B from 7:269 Holothuria tubulosa 15:104;17:134 Holothuria vagabunda 7:267,268 Homarus americanus 19:668 Homoerythrina 6:487 biosynthesis of 6:487 Homphymia conferta 25:793 Hopea brevipetiolaris 23:547 Hopea malibato 23:547 Hordeum 29:593 Hordeum vulgate 21:91,504;27:191, 765;29:593 Hormodendrum sp. 5:325 Hormosira banksii 26:440 Horsfieldia iryaghedhi 5:753 Hortia arborea 4:400 furanocoumarin from 4:398 Hortia regia 22:400 Hoslundia opposita 2:129;22:523 for epilepsy 22:523 for convulsions 22:523 Hosta longipes 21:643 Hosta plantaginea 21:637 Hovenia dulcis Thumb. 15:36;21:659, 674 ;24:273 ;27:40
gymaemasaponin III 27:41,43 gymaemasaponin IV 27:41,43 gymaemasaponin V 27:41,43 gymnemic acid I 27:41,42 gymnemlc acid II 27:41,42 gymnemlc acid III 27:41,42 gymnemlc acid IV 27:41,42 gymnemlc acid IX 27:41,42 gymnemlc acid V 27:41,42 gymnermc acid VI 27:41,42 gymnemlc acid VIII 27:41,42 gymnemlc acid X 27:41,42 gymnemlc acid XI 27:41,42 gymnemlc acid XII 27:41,42 gymnemlc acid XIII 27:42,42 gymnemlc acid XIV 27:41,42 gymnemlc acid XV 27:41,42,45 gymnemlc acid XVI 27:41,42,45 gymnemlc acid XVII 27:41,42,45 gymnemlc acid XVIII 27:41,42,45 hoduloside I 27:41 hoduloside II 27:41 hoduloside III 27:41 hoduloside IV 27:41 hoduloside IX 27:41 hoduloside V 27:41 hoduloside VII 27:41 hoduloside VIII 27:41 hoduloside X 27:41 hovenoside I 27:41 jujubasaponln II 27:41 jujubasaponln III 27:41 jujubasaponln IV 27:41 jujubasaponln V 27:41 jujubasaponln VI 27:41 jujubasaponln zizyphus saponin III 27:41 jujuboside B 27:41 jujuboside B 27:41 saponin C2 27:41 saponin E 27:41 saponin H 27:41 16,17-seco-dammarane triterpene glycoside from 21:659 sitakisoside XIII 27:41 sitakisoside XVI 27:41 sitakisoside XVIII 27:41 sitakisoside I 27:41 sitakisoside II 27:41
1291
sitakisoside III 27:41 sitakisoside IV 27:41 sitakisoside IX 27:41 sitakisoside V 27:41 sitakisoside VI 27:41 sitakisoside VII 27:41 sitakisoside VIII 27:41 sitakisoside X 27:41 sitakisoside XI 27:41 sitakisoside XII 27:41 zlziphin 27:41 Zizyphus saponin I 27:41 Zizyphus saponin II 27:41 Hoxax inella sp. 25:762 Hova austrulis R. 22:523; for convulsions 22:523 Hugonia 26:172 Humboldlia vahliana 22:523 use for epilepsy 22:523 Humicola spp. 2:323 Humulus lupulus 7:121;14:450;21:521, 584 ;23:342;24:902 13-farnesene from 7:121 eudesm-11-en-4-ols from 14:450 (-)-selin-11-en-4a-ol from 14:450 Hunnemannia genera 27:163 Hunteria 13:70,93 indole alkaloids 13:70,93 Huperzia serrata 21:744 Hura crepitans 20:19 Hyalodendron pyrium 5:305 Hyalodendron sp. 5:305;21:218 Hyalomma anatolicum 28:405 Hyalomma genera 28:404 Hyalomma sp. 28:396,407 Hyalophora cecropia 1"206;22:381 Hydnellum (Hydnum) 29:271 Hvdnocarpus wightiana 5:496 Hydnum suaveolens 29:284 Hydractinia echinata 18:701 Hydrangea macrophylla 2:286;13:660; 15:5,30,387;27:7,17 phylloduclin from 13:660;15:30 Hydrangea macrophylla Seringe var. thunbergii 27:17 Hydrellia sp. 22:401 Hydrocotile genera 27:661 Hydrocotyloideae family 27:661
Hydrodictyon reticulatum 18:495,507; 19:247
Hydrogenomonas eutropha 4:439 Hylobius abietis 27:385 Hylomecon genera 27:163 Hylophora cecropia 22:383 Hymenaceae sp. 25:252 Hymenaea ablongifolia 25:252 Hymenaea courbaril 22:66 Hymenaea parvifolia 25:252 Hymeniacidon aldus 21:270 Hymeniacidon sp. 21:349;25:713, 797,798,799,830
Hymenolepis nana 26:484 Hymenoptera 21:612;22:371 Hymenoxys turneri K. Parker 15:32: 27:17,18,35;27:17,18,35 (2R, 3R)-Dihydroquercetin 3-0acetate from 27:17 (2R, 3R)-2,3-Dihydro-5,7,3 '-4"tetrahydroxy-6-methoxy-3- Oacetylflavanol from 27:17 (2R, 3R)-2,3-Dihydro-5,7,3 ',4'tetrahydroxy-6-methoxyflavanol from 27:17 (2R, 3R)-2,3-Dihydro-5,7,4'trihydroxy-6-methoxy-3- Oacetylflavanol from 27:18 Hymeriacidon sp. 25:870 Hyoscyamus albus L. 17:398;22:742 Hyoscyamus genus 17:395 Hyoscyamus muticus 22:742 Hyoscyamus niger 13:631 ;22:523, 721,732,734,742 for epilepsy 22:523 Hyoscyamus sp. 21:104,488 Hypecoideae 27:161 Hypecoum genera 27:163 Hypecoum imberbe 27:167,168 Hypecoum leptocarpum 27:168 Hyperici oleum 22:652 Hypericum 7:409;126:371 Hypericum annulatum 7:417;30:611,616, 619,624 acetylannulatophenonoside from 30:624 annulatophenonoside from 30:624 glycosilated benzophenone from 30:624
1292
phloroglucinol from 30:616 phytochemical studies of 30:611 terpenoid moieties from 30:616 Hypericum ascyron 30:620 in treatment of abscesses 30:620 in treatment of headache 30:620 in treatment of nausea 30:620 xanthones from 30:620 Hypericum barbatum 30:607 hydrocarbons from 30:607 terpenes from 30:607 Hypericum brasiliense 22:656;23:343; 30:611,629 against Bacillus subtilis 30:629 prenylated phloroglucinols from 30:611 phloroglucinols from 30:629 Hypericum calycinum 26:797;30:619 calycinoxanthon D from 30:619 phloroglucinol from 26:797 xanthones from 30:619 Hypericum calycinum 7:422 Hypericum chinense 7:422;22:656 Hypericum drummondii 22:657;30:611 prenylated phloroglucinols from 30:611 Hypericum elegans 30:606 Hypericum erectum 24:273 Hypericum extracts 30:626 in vitro 30:626 inhibitor of dopamine 30:626 inhibitor of noradrenaline 30:626 inhibitor of monoamine neurotransmitters 30:626 inhibitor of serotonin 30:626 Hypericum geminiflorum 30:622 2,3-dihydroxy- 1,6,7-trimethoxyxanthone from 30:622 3,6-dihydroxy-l,5,7-trimethoxyxanthone from 30:622 6,7-dihydroxy- 1,3-dimethoxyxanthone from 30:622 gemixanthone from 30:622 Hypericum genus 30:603 bioactivity of 30:603 secondary metabolites from 30:603 Hypericum hiricnum 22:675
Hypericum hirsutum 22:647;30:606,619 biflavone from 30:619 flavonoids from 30:619 Hypericum humifusum 30:606,619 flavonoids from 30:619 Hypericum hyssopifolium 22:672 Hypericum inodorum 30:619 xanthones from 30:619 Hypericumjaponicum 5:758;22:657; 30:611,614,629 antimicrobial activity of 30:629 as herbal drug 30:614 for gastrointestinal disorders 30:614 for hepatitis 30:614 in diseases 30:614 in treatment of bacterial infections 30:614 prenylated phloroglucinols from 30:611 Hypericum maculatum 22:647;30:619 flavonoids from 30:619 Hypericum montanum 30:606,619 biflavone from 30:619 flavonoids from 30:619 Hypericum mysorense 5:758,759;30:629 against Bacillus coagulans 30:629 against Bacillus megatorium 30:629 against Bacillus subtilis 30:629 against gram-positive organisms 30:629 against Staphyloccus aureus 30:629 Hypericum nummularium 22:647 Hypericum olympicum 30:619 flavonoids from 30:619 Hypericum papuanum 30:616 in treatment of sores 30:616 papuaforins A-E from 30:616 prenylated phloroglucinols from 30:616 tricyclic acylphloroglucinols from 30:616 Hypericum patulum 30:619,622,629 against Eisenia coli 30:629 against Pseudomonas cepacia . 30:629 flavonoids from 30:619
1293
Hypericum perforatum 5:758,656;21:541; 22:643,653,661,664,666,672,673,675,6 76,679-690;25:557 ;29:58030:407, 603,604,605,609,610,616,618,619, 622,624,626-629 against infected wounds 30:628 against skin lesions 30:628 antimicrobial activity of 30:628 antiviral activity of 30:407,627 biflavone from 30:619 cell cultures of 30:609 chemotaxonomic study of 30:619 constituents of 30:605 extract of 30:624 flavonoids from 30:616,618 HPLC of 30:624,626 hyperoside from 30:618 in treatment abdominal pain 30:603 in treatment of isoquercitrin from 30:618 in treatment of melancholia 30:603 in treatment of ulcerated burns 30:603 in treatment of urogenital pain 30:603 in depression treatment 30:624,629 isovaleric acid from 30:605 mechanism of action of 30:624 parts of 30:609 paxanthone from 30:622 pharmacology 30:624 phenotypic characters of 30:604 phloroglucinols from 30:610 c~-pinene from 30:605 quercetin from 30:618 quercetin-arabinoside from 30:616 quercetin-galacturonide from 30:616 quercitrin from 30:618 rutin content of 30:616 rutin from 30:618 subspecies of 30:604 var. angustifolium 30:604 var. microphyllum 30:604 var. perforatum 30:604 varieties of 30:604 veronense from 30:604 volatile oil from 30:605 xanthones from 30:619
Hypericum pulchrum 30:606 Hypericum revolutum 7:409,410,417,420422;22:655 ;23:342
Hypericum roeperanum 29:581 ; 30:619,620 (5-O-demethyl paxanthonin) from 30:620 calycinoxanthon D from 30:619 roeperanone from 30:619 xanthones from 30:619 Hypericum sampsonii 30:622 against diarrhoea 30:622 against snake bites 30:622 against swellings 30:622 Hypericum sarothra 30:605 n-nonane from 30:605 Hypericum scabrum 30:616 hyperibones A-I from 30:616 Hypericum sp. 27:850 Hypericum tatrapterum 30:606,619 flavonoids from 30:619 Hypericum triquetrifolium 22:647,673 Hypericum uliginosum 22:657 Hyphomonasjannaschiana 25:873 Hypocrea muroiana 21:225 hypomurocins A,B from 21:225 Hypocrea sp. 21:203,224 Hypoglottis 27:61 Hypolepis puncatata 26:122 Hypoponera opacior 5:224,230,254 Hypoxvlon oceanicum 25:717 Hypselodoris californensis 6:20 curyfuran from 6:20 Hypselodoris godefroyana 6:69 curyfuran from 6:20 nakafuran-9 from 6:29 Hypselodoris nana 25:815 Hypselodoris porterae 6:20 Hypselodoris webbi 21:361 Hypselodory nana 26:463 Hyptis verticillata 21:599;26:212;28:402 dehydro-[3-peltatin methyl ether from 26:212 5-methoxypodophyllotoxin from 26:212 Hyriopsis schlegelii 26:1123 Hyrtios altum 25:727 Hyrtios erecta 25:696,698,710,819; 28:691
1294
Hyrtios eubamma 6:23 puupehenone from 6:23 Hyrtios sp. 25:716 Hyrtios spicigora 25:276 Hysistozoa fasmeriana 28:635 Hysselodoris califomiensis 4:404 Hysselodoris porterae 4:404 Hyssopus 29:579 Hyssopus officinalis 7:119 Hyssopus sp. 26:746 Hytis spicigora 25:276
lanthella basta 25:719;28:695,714 as Ca2+-channel agonists 28:695
lanthella flabelliformis 28:714 lanthella sp. 28:695 Iberis amara 19:762,20:12 Iberis umbellata 29:53 Ictalurus punctatus 26:353 ledania ignis 28:692 lleostylus micranthus 28:454,464 Ilex aquifolium L. 20:6;22:523 for epilepsy 22:523 llex crenata 21:657 ilexosides A,B,C and D from 21:657 18,19-seco-ursane glycosides from 21:657 Ilex lactone 20:6 llex paraguariensis 20:6;21:671 ;27:299 llex verticillata 9:402 lllicium verum Hook f. 21:596;27:16 trans-anethole from 27:16 llybius fenestratus 5:780 Impatiens repens 22:523 for epilepsy 22:523 Imperata cylindrica 26:233 graminone B from 26:233 Incarvillea sinensis 30:204 incarvillateine from 30:204 Indigofera endecaphylla 19:117;27:522 Indigofera genera 27:519 lndigofera swaziensis 7:417 Indigofera tinctoria L. 22:523 for epilepsy 22:523 Inter alia 26:481 lnula britannica 29:90 lnula cappa 5:678
Inula crithmoides 5:728 Inula nervosa 19:125 lnula viscose 29:87 Ipomoea alba 1:362 alkaloids of 1:362
lpomoea batatas 29:604 lpomoea cairica 26:223 lpomoea hederaceae L. 22:523 for epilepsy 22:523
Ipomoea hispida 22:523 for epilepsy 22:523
Ipomoea muricata 1:362 Ipomopsis aggregata 23:96 Iponuga 27:250 Ipstypographus 27:384,385 Ircinia 21:260 lrcinia dendroides 25:885;28:684 lrcinia fasiculata 28:673 fasiculatin for 28:673
Ircinia sp. 25:688,703,705,709;28:670, 714
lrcinia spinulosa 28:676;29:694 brine shrimp toxicity of 28:676 2-prenylhydroquinones of 28:676 Ircinia sponges 25:695 Ircinia variabilis 28:673 22-O-sulfates of palinurin from 28:673 sulfate esters from 28:673 Ircinia wistarii 6:8 ircinianin from 6:8 wistarin from 6:8 lridomyrmex humilis 5:223,225,240,241, 245,253 Iridomyrmex nitidus 5:222-224,233,253 Iridomyrmex purpureus 5:222,224,233, 253 2,5-dimethyl-3-ethyl pyrazines of 5:222
lridomyrmex purpureus sanguineus 5:224,233,253
lridomyrmex rufoniger sp.gr. 5:223,237, 253
Iris germinica 10:152 Iris japonica 26:433 Irpex lacteus 26:439,468 Iryanthera lancifolia 22:356 dihydrochalcones from 22:356
1295 flavonolignoids from 22:356 tocotrienols from 22:356 Iryanthera sagotiana 22:355 Isatis tinctoria 26:632 lsodictya setifera 25:828 Isodon japonicus 24:273;29:101 lsoopalanoids 6:108 from (+)-labda 8(20),13-diene-15oic acid 6:57 synthesis of 6:119-122 Isoptera 19:118;22:371 Isopyrum thalictroides 29:578 Isotricha 2:294 Itersonilia tilletiopsis 5:291 Iva xanthifolia 5:728 Ixodes ricinus 26:695
Jaborosa bergii 20:180 Jacaranda acutffolia 5:682 Janolus cristatus 28:146 Janua bioticus 17:100 Jasminum grandiflorum 19:152,158159;29:581
Jasminum officinale 7:218,222,223 Jasminum sp. 7:218,219 Jasonia candicans 21:599 Jasonia montana 21:599 Jaspis 5:428,19:580;613; 21:273 ;25:700,714;26:485,488, 1210;28:697 Jaspis coriaceae 25:725 Jaspis splendans 25:768 Jaspis sponges 21:252 jaspamide from 21:252 Jasus lalandii 29:10 Jatropha curcas L. 22:524 for convulsions and fits 22:524 Jatropha gossypifolia L. 10:152;22:524 as anticonvulsant 22:524 Jatropha grossidentata 26:809,810 Jatropha isabelli 26:810 Jatropha multifida L. 22:524 as anticonvulsant 22:524 Jatrorrhiza palmata 27:749 Jereicopsis 26:1175 Jereicopsis graphidiophora 26:1206, 1207,1214 Jerveratrum group 23:563
Jorunna funebris 21:265 Jospis sp. 25:704,719,727,731 Juglans 26:905 Juglans mandshurica 26:899 Juglans regia 21:503;23:342;28:424 Jungermannia infusca 2:280 Jungermanniaceae 25:252
Juniper communis 21:616 Juniperns procera 25:257,259 Juniperus 27:372 (+)-limonene in 27:372
Juniperus virginiana 15:346 Juniperus communis 5:485;20:16 Juniperus foetidissma 8:163 8,14-cedranoxide from 8:163
Juniperus macropoda. 22:524 Juniperus occidenatalis 28:408 Juniperus sabina 20:16;26:214 Juniperus virginiana 20:16;28:408 Juriperus communis 27:370,372 essential oils from 27:370
Jusiaea decurrens 9:214 Justicia procumbens 17:333;26:226, 235,243,265 justicidin B from 26:243 justicidin E from 26:243 neojusticin A from 26:243 taiwanin E from 26:243 taiwanin E methyl ether from 26:243 diphyllin apioside-5-acetate from 26:226 diphyllin asioside from 26:226 diphyllin from 26:226 justicidin A&B from 26:226 Justicidin A 26:194,266 Justicia procumbens var. leucantha 26:226 diphyllin apioside-5-acetate from 26:226 diphyllin asioside from 26:226 diphyllin from 26:226 justicidin A&B from 26:226 Justicia prostata 17:335 Kadsura heterocollita 26:240,249,259 burchellin from 26:249 gomisin M from 26:240 heteroclitin F from 26:259 heterociitin G from 26:259
1296
kadsurenone from 26:249 Kadsura interior 26:223 gomisin-G from 26:223 interiotherin A from 26:223 schisantherin D from 26:223 Kadsura sp. 17:346 Kadsuru japonica 26:255 Kaemferia galanga 24:273 Kaempferia 23:840 Kaempferia galanga 23:840 Kalopanax pictus 30:203 use in folk medicine 30:203 use in rheumatoid arthritis 30:203 Karwinskii 22:555,583,585,586,589,591592,600 Karwinskii calderonii 22:556,560,589 Karwinskii humboldtiana 22:556,558, 559,563,570,572,577,583,585,586, 587,588,589,590,600 Karwinskiijohnstonii 22:556,559,572, 578,585,589 Karwinskii latifolia 22:556,583,589 Karwinskii mollis 22:556,559,572,589 Karwinskii parvifolia 22:56,559,562,563, 567,573,577,583,588,589,592,593, 596,600 Karwinskii rzedowskii 22:556,559,589 Karwinskii subcordata 22:556,559,572, 589 Karwinskii tehuacana 22:556,559,570, 571,589 Karwinskii umbellate 22:556,559,570, 572,588 Karwinskii venturae 22:556,559,589 Khaya grandifoliola 5:700 Khaya ivorensis A. 22:524 for convulsions in children 22:524 Khaya senegalensis A. 22:524 for convulsions in children 22:524 Kigelia africana 7:406 Kigelia pinnata 23:342;29:747 Klebsiella 12:63;26:1155 Klebsiella aerogenes 26:1263,1269 Klebsiella pneumoniae 5:325,308,308, 106,12: 400;20:712;23:136,474; 25:258,259;26:402 Kloechera corticis 25:143 Kloeckera africana 5:283
Kloeckera magna 1:701,283,13 in microbial reduction 6:13 Kluyveromices sp. 13:302 Kluyveromyces fragilis 26:338 Kluyveromyces lactis 26:1127 Knema elegans 21:591 Knemidocoptes pilae 28:415 Kochia prostrata 22:524 Kochia scoparia 24:273 Koelreuteria henryi 27:842;29:581 Kokoona zeylanica 5:743-745;30:642,674 celastrahydride from 30:642 D:A-friedo oleananes from 7:147149 phenolic triterpenes from 7:147149 triterpene quinone methide from 7:147-149 Kopsia dasyrachis Ridl. 21:128;29:363 kopsirachin from 21:128 Krameria triandra 26:204 scavenging activity of 26:204 Labdane xylosides 25:252 Labiatae pinaceae 27:361 Labopghora variegata 25:729 Lachnanthes tinctoria 4:618 Lachnella 26:462 Lachnum papyraceum 25:781,785;26:446 Laciniata furanone 9:532,533 Lactarius camphoratus 17:156 Lactarius chrysorrheus 17:196 Lactartus circellatus 17:197 Lactarlus controversus 17:198 Lactartus deceptivus 17:198 Lactartus deliciosus 17:198 Lactarms deterrimus 17:198 Lactarius flavidulus 17:198,201 Lactarius fuliginosus 17:153,201 Lactarius fulvissimus 17:200 Lactarius genus 17:153,156 sesquiterpenes from 17:159 biogenesis of sesquiterpenes from 17:159 Lactarius glaucescens 17:198 Lactarius glutinopallens 17:199 Lactarius glyciosmus 17:199 Lactarius helvus 17:199
1297 l_zlctarlus indigo 17:199 Lactartus lignyotus 17:200 Lactartus mitissimus 17:200;26:461 Lactartus necator 17:199 Lactarius pergamenus 17:198 Lactartus picinus 196,201 Lactartus piperatus 17:197,198 Lactarlus quietus 17:196 Lactarlus rufus 17:199 l_xtctartus scrobiculatus 17:153,196,197 Lactartus subvellereus 17:198 Lactarlus thejogalus 17:200 Lactarlus torminosus 17:196,197 Lactartus vellereus 17:153,196,197 Lactartus, metabolites 17:154 Lactobacillus helveticus 13:319 Lactobacillus plantarum 23:474 Lactobocillus sp. 25:257,924,927,928 Lactuca sativa L. 26:187;27:217 Lactuca virosa 20:8 Laetisaria arvalis 21:187 Lagenaria leucantha 29:615 Lagenidium callinectes 22:79 Lagerstoroemia 23:405 Lagerstroemia subcostata Koehne 1:368 Lagochilus sp. 22:524 Laguncularia racemosa 7:175 Lamellariidae 17:21,22 Lamellomorpha strongylata 26:1189 Laminaceae 25:171 Laminaria 26:1121 Laminaria abyssalis 30:400 sulphated polysaccharide (PS) from 30:400 Laminariajaponica Aresch. 30:56 fucoidan from 30:56 in arteriosclerosis treatment 30:56 in cancer treatment 30:56 in hyperlipidemia treatment 30:56 Laminaria ochroleuca 22:524 Laminaria pedicularioides 25:868 Laminaria sp. 25:724 Lamium 26:392 Lamorouxia multifida 24:839 glucoside iridoid of 24:839 Lamorouxia rhinanthifolia 24:839 Lamorouxia sp. 24:839 Lampteromyces 29:271 Lampteromvcesjaponicus 26:706
Lansium domesticum 1:658 Lantana camara L. 22:524;23:487, 521,523;27:377,836,29:586 as anticonvulsant agent 22:524 polar constituents from 23:523 lanthella 25:719 Lanthella basta 10:632 bastaxanthins from 6:150 Lardoglyphus konoi 1:696;14:487 pheromone of 1:696 (-)-lardolure from 14:487 Larix decidua 17:332 Larix kaempferi 29:99 Larix leptolepis 20:613;26:185 Larrea divaricata 17:315 Larrea tridentata 5:9;26:187,205,249 Larus asrgentatus 5:837 hemoglobin components of 5:837 Larus philadelphia 5:837 hemoglobin components of 5:837 Lasallia papulosa 5:311 Lasallia pensylvania 5:311 Laserpitium halleri subsp, halleri 5:728 Laserpitium latifolium 5:725,727 Lasiantheae fruticosa 5:728 Lasioderma serricorne (cigarette beetle) 1:695,275 serricornin from 14:275 Lasiodiplodia theobromae 6:557,290,477 Lasioglossumze phyrum 8:222 Lasius niger 6:454 Laspeyresia pomonella 26:231 Laternula elliptica 25:723 Lathyrus odoratus 26:1268 Lathyrus palustris var. pilosus 25:93 Lathyrus satires 25:529;26:1268 Latrinculia brevis 9:20 trunculin-A,B from 9:20 Latrunculia 25:758,822;28:685 discorhabdin A from 28:686 Latrunculia apicalis 18:716;25:708 Latrunculia brevis 25:822 Latrunculia magnifica 21:96;25:874; 28:688 6,7-epoxy-latrunculin from 28:689 latrunculin M from 28:689 28:689 Latrunculia magnifica 21:96 latrunculin B from 21:96 Latrunculia pulpurea 25:760,822
1298
Latrunculia sp. 21:311 Latrunculin magnifica 17:14 Latrunulia monocytogenes 25:450 Launaea cornuta 22:524 for epilepsy 22:524 Laurence genus 25:249 Laurencia brongriartii 25:863 Laurencia concinna 6:24 concinnidiol from 6:24 Laurencia glandulifera 6:63 glanduliferol from 6:63 Laurencia implicata 18:633 brasilane sesquiterpene from 18:633 Laurencia implicata 26:808,809 Laurenciajaponensis 25:803 Laurencia majuscula 6:60 bromochamigrene from 6:60 Laurencia nipponica 6:41,63 (-)-( 2 R, 6S, 9S)-2,8-dibromo-9hydroxy-a-chamigrene from 6:63 (+)-isocycloeudesomol from 6:41 Laurencia obtusa 5:363;8:625 brasilenol from 6:6 brasilenol acetate from 6:6 brasilenol from 6:6 epi-brasitenol from 6:6 Laurencia okamurai 19:454 Laurencia pacifica 6:63 (+)-2-bromo- [3-chamigrene from 6:63 Laurencia perforata 6:29,30,56 Laurencia pinnata 6:9,26;21:252 laurepinnacin from 21:252 Laurencia pinnatifida 5:216,363,81-8 marine sesquiterpenes from 9:81-83 Laurencia poitei 6:35 poitediol from 6:35 Laurencia rigida 25:783 Laurencia saitoi 25:788 Laurencia snyderae 6:6,30 epiguadalupol from 6:30 guadalupol from 6:30 isoconcinndiol from 6:30 Laurencia sp. 5:361-363,368,370; 25:701 ;6:24,59,60;9:8;10:231
(-)-aplysin-20 from 6:24 10-bromo-ct-chamigrene from 6:60 spirobicarbocyclic chamigranes from 6:59 cyclic ethers from 10:213 Laurencia subopposita 6:10 oppositol from 6:9 prepinnaterpene from 6:9 Laurencia venusia 5:361 ' Laurenica 25:701 Laurenica majuscula 25:702 Laurenica nidifica 25:702 Laurenica nipponica 25:702 Laurilia tsugicola 26:703 Laurus azorica 26:850 Laurus nobilis 21:599 Lavandula 29:579 Lavandula angustifolia 7:94,95,108, 109,118,119,125,126;21:612;27:374; 28:411 essential oil of 28:411 constituents of 28:411 Lavandula latifolia 29:91 Lavandula sp. 7:125;22:524 Lavandula spica 21:617 Lawencia clavidormis 25:770 Lawsonia alba 26:837 Lawsonia inermis 30:336 for decoration 30:336 Leathesia difformis 30:405 Lebistes retculatus 26:689 Leccinum 29:271 Ledebouriella seseloides 22:524 for convulsions and spasms 22:524 Ledum palustre 20:17 Legionella pneumophila 13:155 Leguminosae 25:92,180,186,188,246, 248,465 ;26:637,871,931 ;27:443,766 Leishma braziliensis 2:311 Leishmania 2:311-314;18:791,793,794; 26:779,780,783,786,789,790,793,801,8 03,805,807,808,810,821,822,824, 828,830 glycocomplexes of 2:311-314 polysaccharides of 2:311-314 Leishmania adleria 2:311,313 immunity against kala-azar 2:313
1299
Leishmania amazonensis 2:298,794; 23:707 ;26:229,887 amastigotes of 26:828 promastigotes of 26:828 Leishmania braziliensis 29:749 Leishmania decemlineata 26:851-859, 860,863-866 Leishmania donovani 2:311,312;21:744; 25:254,260;26:791,794,797,800,804, 805,806,819,821,828;29:749 glycopetidophosphophingolipid 2:312 polysaccharides of 2:311,312 Leishmania enrietti 2:314;29:749 carbohydrates in 2:314 Leishmania infantum 21:674;26:810; 29:749 Leishmania major 26:230,784,791,800, 805,810,811 ;29:749 Leishmania mexicana amazonensis 2:314 carbohydrates in 2:314 Leishmania panamensis 21:674; 26:821,822 Leishmania tarentolae 2:298,311 carbohydrates in 2:311,314 Leishmania tropica 21:674;26:802 Leishmania tropica major 2:314 polysaccharides in 2:314 Lemna bioassay 9:386,387,389,390; 15:344 Lemna gibba 27:330 Lemna minor (duckweed) 9:383,384, 386,387,389,390 Lemnalia africana 25:695 LendenJeldia chondrodes 25:703 Lens culinaris 21:526;26:1263 Lens esculenta 25:93 Lentinus edodes 5:287,288,316;23:111, 115,131;25:450 Lenzites betulina 29:266;291 Leocalpus j?agilis 21:414 Leontice leontopetalum 9:153 Leontodon hispidus 29:90 Leonurus cardiaca L. 22:525;30:273 for epilepsy 22:525 isoquercitrin from 30:273 Leonurus hereteropyllus 25:272 Lepidium sativum 21:98,109;25:781; 27:217;28:400
in tick toxicity 28:400 Lepidoglyphus 28:432 Lepidoptera 9:322,772;22:371 Leptinotarsa decemlineata 26:850,854, 855,869-872,874,876 Leptochilus acolhuus 5:223,224,253 Leptoclinides dubius 25:719 Leptocoris trivittatus 22:386 Leptodontium elatius 21:193;22:253; 23:344 Leptogenys diminuta 11:415 (3 R,4S)-4-methyl-3-heptanol fi-om 11:415 Leptogorgia virgulata 17:99 Leptomonas collosoma 2:301 Leptomonas samueli 2:298 polysaccharides of 2:301 Lepto~phaeria oraemasis 22:72 Leptosphaeria sp. 25:839,901 Leptosphaerisa oraemaris 23:344 Lespedeza capitata 29:580 Lespedeza sericea 22:95 Lesquerella sp. 13:310 Letharia vulpina 5:310,311,313 Lethasterias nanimensis chelifera 15:59 Leucadendron 4:712 Leucaena leucocephala 26:1142,1148 galactomannans from 26:1148 Leucaena spp. 26:1139 Leucas lavandulifolia 22:525 for convulsion, epileptic seizures and coughing spasms 22:525 Leucas zeylanica R. Br. 22:525 Leucetta chagosensis 17:17 Leucetta microraphis 25:705 Leucocyclies Jbrmosies 10:151 Leucocyclus formosus 21:378 Leucogyrophana 29:271 Leucojum aestivum 20:359 Leucojum vernum 20:359 Leuconitis eugenifolia A. 29:362 Leuconostoc measenteroides 2:350,314, 325,69;7:69 Leuconotis 29:363 Leucopaxillus albissimus 26:493 Leucopaxilus cerealis var. piceina 21 : 190 Leucophaea maderae 9:488,489 Leuocylus formosus 24:686,689 Levisticum 29:581,582
1300
Leyssera guaphaloides 25:250 Liatris cylindracea 24:103 Liatris platylepis 24:103 Libinia emarginata 1:704 juvenile hormone from 1:704 Libium maximowiczii 25:788 Libocedrus bidwilli 26:231 Licania apetala var. apetala 28:41,58 Licania carii 28:38,40-42,60 betulinic acid from 28:42 2ot-hydroxyursolic acid from 28:42 maslinic acid from 28:42 myricetin 3'-methyl-3-O-rutinoside from 28:42 myricetin 3-O-(2"-O-[3-Dxylopyranosyl)-c~-L-rhamnopyranoside from 28:42 myricetin 3-O-rutinoside from 28:42 myricetin 3-O-[3-Dgalactopyranoside from 28:42 myricetin 3-O-[3-Dglucopyranoside from 28:42 phytochemical studies of 28:38 quercetin 3-O-(2"-O-[3-Dxylopyranosyl)-c~-Lrhamnopyranoside from 28:42 quercetin 3-O-rutinoside from 28:42 quercetin 3-O-[~-Dgalactopyranoside from 28:42 quercetin 3-O-[3-Dglucopyranoside from 28:42 [3-sitosterol 3-O-[3-Dglucupyranoside from 28:42 ursolic acid from 28:42 Licania densiflora 28:38,49 3 ',4 '- dimethylmyric etin-3- O- [3-Dglucopyranoside from 28:49 myricetin 3',5'-dimethylether-3-Oot-L-rhamnoside from 28:49 myricetin 3',5'-dimethylether-3-O[3-D-glucopyranoside from 28:49 myricetin 3'-methylether-3-O-[3-Dgalactopyranoside from 28:49 myricetin 3-O-(2"-O-ot-Lrhamnopyranosyl)-a-L-
rhamnopyranoside from 28:49 myricetin 4'-methylether-3-O-ot-Lrhamnopyranoside from 28:49 naringenin 8-hydroxy-4'-methyl ether from 28:49 phytochemical studies of 28:38 Licania densiflora 28:41,60 Licania genus 28:65 Licania heteromorpha 28:65 Licania heteromorpha var. heteromorpha 28:38,40,53, 62 alphitolic acid from 28:53 betulinic acid from 28:53 myricetin 3,4'-di-O-(x-Lrhamnopyranoside from 28:53 myricetin 3-O-o~-Lrhamnopyranoside from 28:53 myricetin 3-O-[3-Dgalactopyranoside from 28:53 myricetin 4'-methylether-3-O-a-Lrhamnopyranoside from 28:53 myricetin 4'-methylether-3-O-[3-Dgalactopyranoside from 28:53 myricetin 4'-methylether-3-O-13-Dglucopyranoside from 28:53 myricetin 7-methylether 3,4'-di-Ocz-L-rhamnopyranoside from 28:53 3 [3-O-cis-p-coumaro yl alphitolic acid from 28:53 3 [3-O-cis-p-coumaro yl maslinic acid from 28:53 3 [3-O-cis-p-coumaroyl-2 ~hydroxy-urs- 12-en-28-oic acid from 28:53 3 [3-O-trans-p-coumaro yl alphitolic acid from 28:53 3 [3-O-trans-p-coumaro yl maslinic acid from 28:53 3 [3-O-trans-p-coumaro yl- 2 cthydroxy-urs- 12-en-28-oic acid from 28:53 phytochemical studies of 28:38 Licania intrapetiolaris 28:38 cucurbitacin B from 28:59 intrapetacin A from 28:59 intrapetacin B from 28:59 phytochemical studies of 28:38
1301
Licania licaniaeflora 28:38,40,56 arjunic acid 28-[3-D-glucosyl ester from 28:57 betulinic acid from 28:57 maslinic acid from 28:57 olean- 12-ene-2~,3[~-diol from 28:57 oleanolic acid 3-O-c~-L28:arabinopyranoside from 28:57 oleanolic acid from 28:57 pomolic acid from 28:57 phytochemical studies on 28:38 tormentic acid 28-[3-D-glucosyl ester from 28:57 ursolic acid from 28:57 Licania michauxii 28:65 Licania pittieri 28:38,42,60 catechin from 28:42 epicatechin from 28:42 phytochemical studies of 28:38 quercetin from 28:42 quercetin 3-O-c~-Larabinopyranoside from 28:42 quercetin 3-O-c~-Lrhamnopyranoside from 28:42 quercetin 3-O-[3-Dgalactopyranoside from 28:42 quercetin 3-O-[3-Dglucopyranoside from 28:42 ursolic acid from 28:42 Licania pyrifblia 28:38,40,42 c~-amyrin from 28:42 betulin from 28:42 betulinic acid from 28:44 2,3-dihydroxylup- 12-en-28-oic 28: acid 3-(3',4'dihydroxybenzoyl ester) from 28:44,45 2 c~,3c~-dihydroxyurs- 12-ene-28-oic acid from 28:45 euscaphic acid 28-[3-Dglucopyranosyl ester from 28:45 euscaphic acid from 28:45 11 c~-hydroxybetulinic acid from 28:44 6[3-hydroxybetulinic acid from 28:44 2c~-hydroxyursolic acid from
28:45 lupeol from 28:42 maslinic acid from 28:45 oleanolic acid from 28:44 phytochemical studies of 28:38 [3-sitosterol 3-O-[3-Dglucopyranoside from 28:45 [3-sitosterol from 28:42 tormentic acid 28-[3-Dglucopyranosyl ester from 28:45 tormentic acid from 28:45 2,3,27-trihydroxylup- 12-en-28-oic acid 3-(3 '-4 '-dihydroxybenzoyl ester) from 28:45 ursolic acid 3-O-c~-L28:arabinopyranoside from 28:45 ursolic acid from 28:44 uvaol from 28:44 Licaria puchury 22:525 Licorice root 22:422 Ligistrum 26:327 Lignincola laenis 25:899 Ligularia fischeri 29:87 Lilium candidum 21:128 lilaline from 21:128 Lilium longifolium 18:507;21:643;25:391 teasterone myristate from 18:507 teasterone 3-myristate from 18:495,522 Lilium nobilissimum 21:643 Lilium speciosum 21:643 Lillium candidum 21:128 Lillium maximowezii 23:341 Limnophila chinensis 22:525 as antispasmodic 22:525 Limnophila chinensis 22:525 Limonia acidissima L. 20:497;22:525 for epilepsy 22:525 Limonia crenulata 22:525 for epilepsy 22:525 Linaria saxatilis var.glutinosa 29:689 Linckia guildingi 7:298 Linckia laevigata 7:290,295,46,61 laevigatoside from 7:290 maculatoside from 7:290 marthasteroside A1 from 7:290 ophidianoside F from 7:290 thornasteroside A from 7:290
1302
Lindbladia tubulina 29:254 Lindera umbellata 28:419 Lineus fuscoviridis 18:725 Lingbya majuscula 25:876,902 Linum 26:172,173 Linum album 26:173 Linum flavum 26:173,212 5-methoxypodophyllotoxin from 26:212 Linum usitatissimum L. 22:525;26:206; 29:608 for hysteria 22:525 Lippa dulcis Trev. 24:799;27:13,21 (+)-hernandulcin from 27:13,21 4[3-hydroxyhernan dulcin from 27:13,21 Lippia alba 21:617 Lippia dauensis 21:595 Lippza grandifolia 21:595 Lipptajavanica 21:595 Lippta multiflora 21:613 Lippta nodiflora 5:647,648,655 Lippla somalensis 21:595 Lippta sp. 7:427 Lippia ukambensis 21:595 Lippia wilmsii 21:595 Lipria dulcis 15:14 Liquidamber formosana 23:405 Liriodendron tulipifera 5:476 Lissoclinium patella 25:879,880 Lissoclinum 25:707,821,833,834,862,878 Lissoclinum bistratum 10:243;25:881, 882;28:628 bistratamide A from 28:628 bistratamide B from 28:628 bistratamide C from 28:628 bistratamide D from 28:628 Lissoclinum fragile 23:262;25:782 Lissoclinum genus 25:833 Lissoclinum japonicum 25:833;28:637 dimethyl-5-(methylthio) varaein from 28:637 Lissoclinum lisschlinotoxin A 25:833 Lissoclinum patella 25:878,891 ;28:622, 623,625,626,627,629 ascidiacyclamide from 28:622 heptapeptide ulicyclamide from 28:622 patellamide A from 28:623
patellamide B from 28:623 patellamide C from 28:623 patellamide E from 28:627 patellamide F from 28:627 patellamide G from 28:627 patellazole A from 28:625 patellazole B from 28:625 patellazole C from 28:625 patellins 1-6 from 28:629 prepatellamide A from 28:626 tawicyclamide A from 28:629 tawicyclamide B from 28:629 trunkamide A from 28:629 ulithiacyclamide B from 28:623 ulithiacyclamide from 28:622 Lissoclinum patella 4:89,93,99,5:419, 420,10:242,243 ;28:624 Lissoclinum perforatum 10:244;23:236; 25:833;28:636 1,2,3-trithiane derivative from 28:636 Lissoclinum sp. 28:636 lissoclinotoxin A from 28:636 lissoclinotoxin C from 28:636 lissoclinotoxin D from 28:636 trithiane from 28:637 Lissoclinum tunicate 28:715 Lissoclinum vareau 10:243;23:236; 25:871,833 varacin from 28:637 varamine A from 28:638 Lissoclinum voeltakowi Michaelson 25:269 Lissodendoryx isodactyalis 5:395,13:168, 18:715,716 Listera ovata 26:1135 Listeria monocytogenes 21:618;27:381; 30:766,767,773 host defense against 30:766 in immune response 30:773 Lithistida 28:658 Lithospermum 22:76 Lithospermum erythrorhizon 7:88;30:345 BK-39 callus culture of 30:345 shikonin from 7:88 Litsea cubeha 25:132 Litsea odorifer 24:275 Lituaria australasiae 19:596
1303
Lobaria retigera 13:22 (-)-retigeranic acid from 13:22 Lobelia inflata L. 22:525;29:583 for epilepsy, hysteria and convulsions 22:525 Lobophylum crassum 8:11 isolobophytolide from 8:20 Lobophytum pauciflorum 21:276 Lobophytum sp. 21:276 Lochnera (Vinca) rosea 1:125 Locusta 9:489 Locusta migratoria 22:387,398; 24:115,116;29:6 Locusta migratoria manilensis 18:771 Locusta migratoria migratorides 7:395, 18:771 Lolium multiflorum Lam. 27:217 Lolium perenne L. 26:696;27:217 Lonchocarpus 26:487 Lonchocalpus capassa 29:598 Lonchocarpus minimifloru 29:782 Lonchocarpus subglauscescens 29:780 Lonchocalpus urucu 28:435 Lonchura malabarica 5:837 hemoglobin components of 5:837 Lonchura malacca 5:837 hemoglobin components 5:837 Lonchura punctulata 5:837 hemoglobin components 5:837 Lonicera fulvotomentosa 21:656 fulvotomentosides from 21:656 Lonicera nigra 7:427 Lopharia papyracea 29:265 Lophozozymus pictor 5:393 Loropetalum chinense 23:405 Lotus corriculatus 25:93 Lotus uliginous 19:117 Luffa acutangula 29:615 Luffa cylindrica 21:67122:116,120; 29:575,587,615 Luffariella variabilis 17:10;18:717; 21:252;25:696 Luidia maculata 7:303-306,15:46 luidiaglycosides A-D from 7:288 maculatoside from 7:289 marthasterosides from 7:289 thornasteroside A from 7:289 Lumbricus 30:828 from Lumbricidae family 30:828
Lumbricus bimastus 30:827,828 from Lumbricidae family 30:828
Lumbricus castaneus 30:828 from Lumbricidae family 30:828
Lumbricus rubellus 30:825,840 lyophilized powder of 30:840
Lumbricus rubellus (humus earthworm) 30:826-828,833 assay of 30:833 earthworm fibrinolytic enzymes from 30:826 from Lumbricidae family 30:828 isozymes of 30:826 Lumbricus terrestris (common earthworm) 30:828 from Lumbricidae family 30:828 Lumnitzera sp. 7:176 Lupeol 7:189 Lupinus albus 26:931 ;27:271,276 Lupinus anagyroides 27:283 Lupinus angustifolius 27:276 Lupinus hartwegii 27:273 Lupinus luteus 15:521 ;27:267;29:587;782
(- )-( trans-4 '-~3-Dglucopyranosyloxy-cinnamoyl) lupinine from 15:521
(-)-( trans-4'-[3-Dgluc op yrano sylo xy-3 'methoxycinnamoyl) lupinine from 15:521
(- )-( trans-4 '-hydro x y-c innamo yl ) lupinine from 15:521
(-)-( trans-4 '-rhanm o sylo x ycinnamoyl) lupinine from 15:521
(-)-( trans-4 ' -rhamno sylo x y- 3 'methoxy-cinnamoyl) lupinine from 15:521 Lupinus mutabilis 27:278 Lupinus polyphylus 25:94 Lupinus sp. 27:273,268 Lupinus termis 15:524,525 (-)-AS-dehydroalbine from 15524 (-)-AS-dehydromultiflorine from 15:525 Lupinus varius 27:273 Luttariella sp. 25:694 Lutzomyia 26:783 Lychnophora sellowii 8:48 bisabolone from 8:48
1304
Lycium chinense 22:721 Lycogala epidendrum 29:230,231,233 2D-NMR spectroscopy of 29:230 anti HSV-I virus activity of 29:230 arcyriaflavin A from 29:231 arcyriarubin A from 29:231 as myxomycete species 29:230 fruit bodies of 29:231 lycogarides as 29:233 lycogarubins from 29:230 staurosporinone from 29:231 triglycerides as 29:233 Lycopersicon esculentum 18:523,529, 532,533 ;25:294,298,657 ;29:591,604,6 08,610
Lycopersicon hirsutum f. glabratum
28:433 2-undecanone from 28:433 methyl ketones 2-tridecanone from 28:433 Lycopersicon peruvianum 25:372-375 Lycopersicon pimpinellifolium 25:294, 298 Lycopersicon sp. 25:293,315 Lycopersicum esculentum 22:721 Lycopersion sp. 22:344 Lycopodium alkaloids 16:456;18:341 Lycopodium magellanicum 18:3 Lycopodium paniculatum 18:3 Lycopodium selago 21:746 selagin from 21:746 Lycopodium serratum 21:744 Lycoris incarnata 20:351 incartine from 20:351 Lycoris radiata 26:614 Lygos raetam var. sarcocarpa 27:269 Lyngbia gracillis 19:586 Lyngbia majuscula 19:492,587 Lyngbya bouillonii 25:891 Lyngbya genus 25:891 Lyngbya gracilis 17:4 Lyngbya lagerheimii 25:868 Lyngbya majuscula 5:411 ;18:294 11:278 ;21:415 ;23:344 ;25:716,722, 732,761,785,787,889; 26:78;28:143 lyngbyatoxin from 11:278 pukeleimide A,B,F and G from
21:415 pukeleimide C from 28:143 Lyngbya toxin A 5:412 cytotoxic activity of 5:411 Lyngbya wollei 26:355 Lyrophagus longior 28:419 Lytechinus variegatus 7:285;15:104 lytechinastatin from 7:285 Lythrum aceps 23:404
Maackia amurensis 15:521,522 (+)- 13[3-hydroxymamanine from 15:522 (-)-lusitanine from 15:521 Maackia tashiroi 15:523 tashiromine from 15:523 Macaronesia fortunata 26:850 Macfadyena unguis-cati 29:696 Machilusjaponica 26:857 bioactive lignans from 26:857,858 Machilus thumbergii 26:247 Macleaya cordata 27:155,159,162,864 Macleaya microcarpa 27:155,159,162 Macleaya sp. 27:162 Maclura pomifera 25:39'~ Macrocystis alterniflorum 26:359 Macrocystis spicatum 26:359 Macrocystis vet' ilatum 26:359 Macronesia fort,nata 26:850,851 Macrophiotrix longipeda 7:309 Macrophomis phaseolina 6:555 Macropiper excelsum 22:393 Macrotyloma axillaris 29:598 Macrozamia communis 26:366 Maerua angolensis DC. 22:525 for epilepsy 22:525 Maesa lanceolata 5:819;17:240;21:665 Magnifera indica 9:321 Magnolia acuminata 24:845-847 Magnolia biondii 24:845,854 PAF antagonists of 24:854 Magnolia compbellii 24:849,857 Magnolia denudata 24:845,848,860; 26:245,247 Magnolia fargesii 24:854,862;26:233 denudatin B from 26:233 fargesin rrom 26:233 fargesone A-C from 26:233
1305 lirioresinol-B dimethyl ether from 26:233 magnolin from 26:233 magnone A&B from 26:245 PAF antagonists of 24:854 pinoresinol dimethyl ether from 26:233 schisandrol A from 26:245 Magnolia grandiflora 24:845,848,850, 856,858,859,863 Magnolia henryii 24:855 Magnolia kobus 24:846,860,862 Magnolia liliflora 24:854,855,860 5-1ipoxygenase-inhibitory activity of 24:855 neurotropic activity of 24:854 Magnolia mutabilis 24:849,857 Magnolia obovata 24:854,855,857; 26:226,227,254 ;29:582 Magnolia officinalis 22:525;24:228,261, 846,849,851,855;26:226,249;27:853; 29:582 anti-tumor activity of 24:849 magnolol from 26:249 Magnolia officinalis var. biloba 24:846 Magnolia salicifolia 17:348;24:846,860, 887,888;26:233 Magnolia saulangiana 24:854 Magnolia sieboldii 24:848;29:89 Magnolia sp. 8:159;24:845-873; 26:240, 270 biologically active compounds from 24:845-873 honokiol from 26:240,270 magnolol from 26:240,270 neolignans from 8:159 Magnolia sprengeri 24:845,849,851 Magnolia tripetala 24:847 Magnolia virginiana 24:845,847; 26:203,232 4,4'-dialyl-2,3'-dihydroxybiphenyl ether from 26:232 magnolol from 26:232 4-methoxyhonokiol from 26:232 Magnolia watsonii 24:855,857 Magnoliae cortex 26:204 honokiol from 26:204 magnolol from 26:204 Magololia officinalis 29:582
Majidea fosteri 7:139,141 majideagenin from 7:141 triterpenoids of 7:139,141 Malacosoma americana 23:661 Malampsori lini 25:397 Mallotusjaponicus 23:406 Mallotus philippinensis 27:853 Malus domestica 29:577,582 Malus sylvestris 21:503 Mammea africana 7:417 Mammea americana 4:389,391 coumarins from 4:389,391 Mammea longifolia 4:389,391 coumarins from 4:389,391 sarangin B from 4:391 Mandragora 21:104 Mandragora officinarum 13:631 ;22:734 Mandshurin manica bradleyi 5:250 Manduca sexta 1:704; 21:252;22:38,387; 26:439;29:6 juvenile hormone from 1:704 Mangifera indica 29:588 Mangifera odorata L. 22:525 for hysteroepilepsy 22:525 Manica bradlyi 5:250 Manica hunteri 5:250 Manica mutica 5:250 Manica rubida 5:235,254 2,5-dimethyl-3-methyl-pyrazines of 5:222 methyl pyrazine of 5:222 Mantella basileo 27:246 Mantella sp. 27:244 Maprounea africana 22:525 Marasmius 26:462 Marchantia paleaceae 2:281 Marchantia palmata 2:283 Marchantia polymorpha 25:423 Marchantia tosana 2:281 Margarita 22:559 Margaritaria discoidea 28:395 acaricidal properties of 28:395 against Amblyomma variegatum 28:395 Marinomonas mediterranea 25:719 Marjoram hortensis (sweet marjoram) cyclase from 11:221 Marquesia 23:532
1306
Marrubium alysson 30:266 7-glucoside from 30:266 Marrubium vulgare 30:266 luteolin from 30:266 Marshallia tenufolia 10:442,443 Marsilea minuta 22:526 Marsilea rajasthnensis 22:526 Marsilea sp. 22:525 Marthasterias glacialis 7:289,299; 15:48,104 glacialosides A,B from 7:299 Martynia annua L. 22:526 for epilepsy 22:526 Martynia chamomilla L. 22:526 for hysteria 22:526 Martynia diandra 22:526 for epileptic attacks 22:526 Massoia lactone 3:157,158 Matricaria aurea L. 22:526 for hysteria 22:526 Matricaria chamomilla 22:669 Matteuccia orientalis 22:169 Matthiola fruticulosa 26:1075 Mayenus ebenifolia 23:657 Maytennus umbellata 23:652 Maytenus amazonica 23:656;30:672, 674,679 dispermoquinone from 30:672 phenolic triterpenes from 30:679 structure of 30:674 Maytenus aquifolium 23:656;30:639 cyclase activity of 30:639 Maytenus arbustifolia 23:656 Maytenus blepharodes 23:656;30:684 dimeric compounds from 30:684 Maytenus boaria 18:752,775;23:656,665 Maytenus buchanii 7:146 tissue culture of 7:146 triterpenes of 7:146 Maytenus buchanim i21:442 maysenine from 21:442 Maytenus buxifolia 18:757;23:657 Maytenus canariensis 23:652,657,669; 30:667 iguesterine from 30:667 Maytenus chuchuasea 23:657 Maytenus cuzcoina 29:87,88
Maytenus dispermus 30:672 7-oxoquinonemethide dispermoquinone from 30:672 Maytenus diversifolia 7:152;23:727 maytensifolic acid from 7:152 maytensifolia A,B from 7:152 maytensifoliol from 7:152 triterpenoids of 7:152 Maytenus emarginata 23:657 Maytenus genus 18:739,740 Maytenus heterophyla 23:657 Maytenus horrida 30:666 netzahualcoyene from 30:666 Maytenus idaea 23:659 Maytenus ilicifolia 23:657,694;24:285,287 Maytenus krokovii 23:658,692 Maytenus laevis 23:658 Maytenus macrocarpa 30:657 dammarane triterpenes from 30:657 Maytenus magellanica 30:684 dimeric compounds from 30:684 Maytenus obscura 23:658 Maytenus ovatus 4:492;23:70 Maytenus peduncularis 23:658 Maytenus putterlickioides 23:658 Maytenus rigida 18:771 wilfordin from 18:771 Maytenus scutioides 23:713 ;30:665,692 fluoride derivatives from 23:713 15ot-hydroxypristimerin from 30:665,692 scutione derivatives from 23:713 Maytenus senegalensis 23:659 Maytenus serrate 21:442 maysenine from 21:442 Maytenus sp. 30:693 against Candida albicans 30:693 against gram-negative bacteria 30:693 against gram-positive bacteria 30:693 Mechilin racemosus 26:1093 Meconopsis genera 27:163
Medicago hispida 516 Medicago polymorpha 25:93 Medicago sativa 15:202,20:734;21:518, 662 ;23:343 ;26:69629:585
1307 medicagenic acid glycoside from 21:661 Medicago scutellata 29:598 Medicago trunuclata 25:379 Megalobulimus paranaqnensis 2:306 Megnaporthe grisea 25:322 Melaconis thelebola 26:596 Melaleuca acacoides 28:419 Melaleuca alternifolia 21:615;28:415; 29:83 Melaleuca argentea 28:418 Melaleuca dealbata 28:418 Melaleuca leucadendron 15:387 phyllodulcin from 15:387 Melaleuca quinquenervia 21:616 Melaleuca saligna 28:418 Melaleuca sp 28:418 Melaleuca ~ymphycarpa 28:419 Melannorrhea usitata 9:319 Melanoplus sanguinipes 22:40 Melastoma malabatricum 23:404 Melastoma normale 23:404 Meleagris gallopavo 5:836 hemoglobin components of 5:836 Melia azedarach 9:502;22:526; 26:187;28:424 Melia cultivar 26:466 Melilotus officinalis 23:337;25:93,132 Melinis minutiflora 28:398 ~- and ~-pinene from 28:398 Melissa 29:581 Melissa officinalis L. 2:404;22:526 callus cultres of 2:404 for epilepsy and hysteria 22:526 Mellettia ferruginea 29:775 Mellittia usaramensis 22:526 for convulsions 22:526 Melodinus australis (F. Muell.) 29:362 Melodinus monogynus 25:276 Melodium fruticosum 1O:152 Melodorum fruticosum 9:399 MeloidogTne arenaria 26:456 Meloidogyne incognita 26:434,435,437, 439,447-450,460,462,463,466,467, 469,471,473,476,483-493,1289 Meloidogynejavanica 26:429,430,456, 464,466,473,478,482 Meloidogyne spp. 26:428,430,432,437, 481,487
Melophlus sarassinorum 28:116 Melospiza lincolnii 5:837 hemoglobin components of 5:837 Melospiza melodia 5:837 hemoglobin components of 5:837 Membranipora membranacea 17:93 Membranipora perfragilis 17:91 ;21:265; 25:825 Menippe mercenatia 19:628 Mentella genus 7:124,126;19:4; 27:375;29:579 Mentha aevensis 30:207 menthol from 30:207 Mentha arvensis 21:618 Mentha haplocalyx 30:219 neolignans from 30:219 Mentha lavandulacea 30:262 kaempferol 3-O-glucosyl( 1() rhamnoside-7-O-glucoside from 30:262 Mentha longifolia 7:119;27:375;30:261 isoorientin from 30:261 longitin from 30:261 vicenin-2 from 30:261 Mentha piperita 25:155;27:375; 29:579;30:207 menthol from 30:207 Mentha pulegium 25:156;27:375 Mentha sp. 21:599;26:746;29:83 Mentha spicata 21:599 Mentha ~picata cv. lacinata 7:119 Mentha sylvestris 27:375 Mercurialis annua 17:117 Meretrix petechialis 30:400 sulphated [3-galactans from 30:400 Merulius sp. 9:317,327,350 Mesona polustris 24:275 Mesoponera castanea 5:224-227,229, 245,247,254 Mesoponera castaneicolor 5:224-227, 229,245,257,254 Mesoponera sp. 5:224-227,245,247,254 Messor barbarus 22:81 Mesua ferrea 4:768 coumarins from 4:389,391 Mesua genus 19:768 Mesua thwaitesii 4:389,391 coumarins from 4:389,391
1308
Metarhizium anisopliae 12:313;19:486; 27:255 ;28:397,404 control of 28:397 in goats 28:394 in sheeps 28:394 (-)-swainsonine from Metarrhizium sp. 21:224 Metatrichia vesparium 12:366,370; 29:232 antibiotic properties of 29:232 arcyrialflavin B from 12:366,370 arcyrialflavin C from 12:366,370 vesparione from 29:232 Methanobacterium thermoautotrophicum 9:606 Metridium illicifolia 18:665 Metridium loesner 18:757 Metridium senile 18:813 Micale cecilia 21:211 Miconia myriantha 29:571 Microbacterium lacticum 26:1122 Micrococcus flavus 12:400 Micrococcus luteus 12:400;13:283; 15:389;21:275;23:252;24:713 ;25:258, 722,777,778;30:693,738 antifungal activities against 30:738 minimal inhibitory concentration (MIC) of 30:693 Micrococcus lysodeikticus 26:1122,1124 Micrococcus sp. 21:259;25:48,79,94,719; 26:1155 Microcosmus vulgaris 28:721 Microcyctis aeruginosa 25:799 Microcystis aeruginosa 26:359,365,366, 367 Microcystis genera 27:879 Microcystis microcystins 25:543 Microcystis sp. 26:258,352,354 Microcystis viridis 26:366 Micromelum compressum 22:526 for convulsions 22:526 Micromelum tephrocarpum 26:800 Micromeria fruticosa 27:377 Micromonospora echiospora 25:796 Micromonospora lacustris 23:55 Micromonospora sp. 23:57;25:841 Microscleroderma sp. 26:1175,1215, 1217,1218 Microsporum canis 12:400
Microsporum canis 21:602;26:227,228 Microsporum guinckeanum 5:294 Microsporum gypseum 12:400;21:602, 758;26:228 Microsporum sp. 26:1127 Microtus montanus 27:213 Microxina sp. 28:691 Mikania cordifolia 22:353 Mikania guaco 29:89 Mikania obtusata 26:810 Milius banacea 20:483 exoaporphines of 20:483 Milleria cordifolia 29:89 Milleria guaco 29:89 Milleria quiqueflora 29:89 Milletia pachycarpa 29:771 Millingtonia hortensis 5:14 Mimosa hostilis 25:248 Mimosa pudica 26:481 Mimosa tenuiflora 24:151,152 Mimulus sp. 6:137 mimulaxanthin in 6:137 Mimusops elengi 23:487 Minoyobates bombetes 19:81 Mirabilisjalapa 23:342 Mitaria coccinea 25:251 Moghania strobilifera L. 22:526 for epilepsy 22:526 Molamola 25:872 Molinema dessetae 26:441 Momordica charantia 29:608,615 Momordica charantia 29:615,616 Momordica cochinchinensis 29:616 Momordica repens 29:616 Monascus ruber 19:168;22:251 Monascus spp. 22:251 Moneses uniflora 25:777 Monilia spp. 2:323 Monilinia fructicola 23:142 Monilinia fructigena 5:278 Monmorium pharaonis 21:277 Monocalyptus subgenus 24:233 Monodora tenuifolia 2:446 2-dimethylallylindole from 2:446 Monohba quadridens 5:225,231,253 Monomirium foricola 6:436 pyrrolidine venom alkaloids in 6:436
1309
Monomorium carbonarium 6:436 pyrrolidine venom alkaloids m 6:436 Monomorium cyaneum 6:436 pyrrolidine venom alkaloids in 6:436 Monomorium ebeninum 6:436 pyrrolidine venom alkaloids in 6:436 Monomorium latinode 16:441 pyrrolidine venom alkaloids In 6:436 Monomorium minimum 6:436 pyrrolidine venom alkaloids m 6:436 Monomorium minutum 6:436 pyrrolidine venom alkaloids in 6:436 Monomorium near emersoni 6:436 pyrrolidine venom alkaloids m 6:436 Monomorium near metoecus 6:436 pyrrolidine venom alkaloids in 6:436 Monomoriumpharaonis L. 1:389;6:336, 445,454;14:575 indolizidine alkaloids in 6:445 pyrrolidine venom alkaloids in 6:436 (+)-monomorine I from 11:231 Monomorium sp. 6:443 2,5-dialkylpyrrolines in 6:434,443 trans-2,5-dialkylpyrrolidines in 6:434 pyrrolidine venom alkaloids in 6:436 Monomorium subopacum 6:436 Monomorium viridum 6:3436 Monotes engleri 23:552,555 Montanoa frutescens 24:806-811 phytochemicals from 24:806-811 Montanoa spp. 24:804-814 Montanoa tomentosa 24:799,804-817 phytochemicals from 24:807-811 Montezuma speciosissima 29:586 Morgula manhattensis 23:243 Morinaga oleifera for 22:526 Morinda lucida 7:427;26:673,805 Moringa concunensis 22:526
Moringa oleifera 22:526 for epilepsy and hysteria 22:526 for nocturnal epilepsy 22:526 Mortania palmeri 5:678 Mortierella alpina 26:259 Mortierella ramannianus 19:578 Mortonia greggi 18:751 Morus alba Linne 17:47,451,465; 29:573,585;28:200,208;29:580;582 cell cultures 17:471 moracenin A and B from 4:618, 619 polyprenols from 8:36 Morus alba spp. 29:573 Morus bombycis 22:117;28:200 Morus cathayana 28:202,234 Morus lhou 28:200 Morus mongolica 29:705 Morus nigra 30:207 use as anti-inflammatory agent 30:207 use in folk medicine 30:207 Morus sp 28:207,221. anti-hyperglycemic effect of 24:917 inhibition of histamine release 24:914-917 Morus uralensis 28:234 Moschus moschiferus 8:219;24:906 muscone from 8:219 Mucor circinelloides 25:166 Mucor miehei 13:303;25:259 Mucor mucedo 21:607,608,611;30:739 antibacterial activity against 30:739 antifungal activity against 30:739 Mucor plumbens 25:253 Mucor racemosus 22:627 Mucor ramannianus 23:23,42,45 Mucor rhizopus 9:203 Mucor rouxianus 21:396 Mucor rouxii 5:276 Mucor sp. 2:323;25:723 Mucuna aterrima 26:435 Mucuna has~joo 26:932 Mucunu sempervirens 25:93 Mugil cephalus 18:486 Mugil umbelata 18:665 Munnozia maronii 26:808
1310
Muntingia calabura L. 22:526 as antihysteric 22:526 Murex truncatus 28:652 Muricella sp. 25:704 Murraya 1:172 Musa acuminata 26:474 Musa basjoo 24:273 Musa paradisiaca L. 22:526 for epilepsy and hysteria 22:526 Musca domestica 18:698,19:124;21:379; 24:115,716;26:231;27:384;29:25 Mussaenda 25:180,183 Mutatis mutandis 15:262 Myasthenia gravis 26:486 Mycale 25:698,727,831,892 Mycale adhaerens 15:386,19:558,613 Mycale sp. 5:366;9:19,22,24;28:712 Mycelia sterilia 9:203;26:482 Mycobactericum tuberculosis H37R 4:244 Mycobacterium 7:327;23:10; 24:713,733 ;26:1122 (all E) phytoene from 7:327 Mycobacterium avium 13:183;23:95; 26:1160
Mycobacterium avium-intracellulare 2:424;21:296
Mycobacterium fallax 26:69 Mycobacterium intracellular Mycobacterium intracellulare 2:428; 25:259
Mycobacterium leprae 9:322;23:136; 30:119 leprosols from 30:119 resorcinolic lipids derivatives from 30:119 Mycobacterium luteus 26:1122 Mycobacterium malmoense 26:1122 Mycobacterium phlei 12:103 Mycobacterium rhodochorus 25:156 Mycobacterium smegmatis 12:400; 23:474;26:227,1123,1155 Mycobacterium tuberculosis 12:398; 18:351 ;21:296;23:53 ;24:713 ;25:779; 26:1122,1155 ;27:284 Mycobacterium tuberculosis var. hominis 26:673 Mycobacterium vaccae 9:411 Mycoplasma sp. 12:48 Mycosphaerella lethalis 26:451
Mycosphaerella pinode 5:278 Mylabris cichorii 27:882 Mylabris phalerata 27:882 Mylitta lapidescens 22:527 for epilepsy 22:527
Myoporum bontioides 15:229 Myoporum deserti 15:228,229 Myoporum laetum 15:236 (-)-ngaione from 15:236
Myoporum montanum 15:229 Myoporum sp. 15:227 Myoporum tenuifolium 29:579 Myrcena citricolor 21:206 Myrciaria dubia 22:359 Myriapora truncata 17:77 Myriastra clavosa 27:879 Myrica 17:375;26:905 Myrica gale var. tomentosa 26:895,899 Myrica nagi 17:371 Myrica rubra 17:371 ;26:895 Myrica salicifolia 22:527 for convulsions 22:527
Myriogloia sciurus 9:83,84 marine sterols from 9:83,84
Myriophyllum 26:359 Myriophyllum spicatum 26:378 Myristicafragrance 21:594;26:226,858 dihydrodiisoeugenol from 26:226 5'-methoxydehydrodiisoeugenol 26:226 Myrmecia gulosa 5:223,233,254 Myrmecocystus testaceus 15:383 Myrmica 6:454 Myrmica afracticornis 5:250 Myrmica americana 5:250 Myrmica brevispinosa 5:250 Myrmica emergana 5:250 Myrmica lobicomis 5:233,235,236,254 2,5-dimethyl-3-ethyl-pyrazines of 5:222 Myrmica rubra 5:235,250,254 2,5-dimethyl-3-methyl-pyrazines of 5:222 2,5-dimethyl pyrazines of 5:222 methyl pyrazines of 5:222 Myrmica ruginodis 5:235,236,254 2,5-dimethyl-3-ethyl-pyrazines of 5:222
1311
Myrmica rugulosa 5:235,254 2,5-dimethyl-3-ethyl-pyrazines of 5:222 Myrmica sabuleti 5:235,254 2,5-dimethyl-3-ethyl-pyrazines of 5:222 Myrmica scabrinodis 5:235,236,254 2,5-dimethyl-3-ethyl-pyrazines of 5:222 2,5-dimethyl-3-methyl-pyrazines of 5:222 2,5-dimethyl pyrazines of 5:222 Myrmica schencki 5:235,254 2,5-dimethyl-3-ethyl-pyrazines of 5:222 Myrmica sp. 5:233,235,236,250,254 2,5-dimethyl-3-ethyl-pyrazines of 5:222 Myrmica sulcinodis 5:235,236,254 2,5-dimethyl-3-ethyl-pyrazines of 5:222 Myrmicaria eumenoides 27:240 Myrmicinae 6:421,422,454,455 Myrothecim verrucaria 21:235 Myrothecium hapla 26:464,474 Myrothecium roridium 21:238 wortmannin from 21:238 Myrothecium sp. 21:233 Myrothecium verrucaria 21:235 myrocin B and C from 21:235 Myrrhis odorata Scop. 15:29;27:16 Myrsine africana 9:400 Myrtus communis L. 22:527 Mystroxylon aethiopium 23:659 Mytenus macrocarpa 30:659 dammarane triterpenes from 30:659 Mytilus edulis 6:142,143,156;17:21; 28:654 Mytilus galloprovincialis 28:654 Myxococcus xanthus 10:78,79;28:144 Myxoderma platiacanthum 15:58,75,81 313,5,613,15~-tetrahydroxy-5 c~stigmastan-29-oic acid from 15:81 Myxoderma platyacanthus 25:872 Myzus persicae 22:95;23:302;26:850, 851,859,861,862
Nadsonia fulvescens 5:290 Naja naja 22:132 Najas sp. 26:361 Narburgia stuhlmanni 1:701,702 antifeedant from 1:701,702 Narcissus alkaloids 20:233 Narcissus pallidulus 20:234 mesembrenone from 20:234 Narcissus pseudonarcissus 20:353, 359,391 ;22:459;26:608 lycorine from 20:233 Narcissus tazetta 26:610,618 Nardoa gomophia 15:46 Nardoa novaecale donia 7:298 halityklosides A,B,D from 7:298 Nardoa tubercolata 15:71 Nardostachysjatamansi DC. 14:375; 22:527 for epilepsy, hysteria 22:527 for convulsive affections 22:527 for hysteroepilepsy 22:527 guaiane alcohol from 14:375 (-)-nardol from 14:374 Naringenin chalcone 23:746 Nasutitermes ephratae 27:385 Nasutitermes exitiosus 5:702;21:277 Nasutitermes nigriceps 27:385 Nauclea latifolia 26:1036 Naufraga 27:661 Nauphoeta cinerea 9:488,489;22:378 Navanax inermis 10:152;17:28 Naviculla pelliculosa 26:358 Neamphius huxleyi 28:688 neamphine from 28:688 Necator americanus 26:425,481,494 Nectandra salicifolia 20:522 Nectria coccinea 21:227 Nectria fuckeliana 15:383 Nectria gibberella 9:203 Nectria haematococca 18:709 Nectria sp. 21:224 Neiso~perma glomerata 1:124 Neisseria 12:63 Neisseria gonorrhoeae 26:673 Neisseria meningitides 4:196,206 diheptoses in 4:196,206 Neisseria meningitidis 29:324 Neisseria perflava 7:69 Nemalion vermiculare 26:1137
1312
Nematoctonus robustus 23:343 Nematospiroides dubius 12:3 Nenrasapora crassa 25:304 ergosterol mutants of 25:304 Nenum oleander L. 22:527 for epilepsy 22:527 Neolitsea sericea 28:419,422 24Z-ethylidenelanost-8-en-328:one from 28:422 24-methylenelanost-8-en-328:one from 28:422 lanostanes from 28:422 Neorautanenia pseudopachyrrhiza 7:417 Neoseiulus fallacis 28:434 Neosiphonia superstes 19:596,19:607; 25:731 ;26:1207-1210 Neosmilaster georgianus 15:58 Neothyone gibbosa 15:92 neothyoside A from 15:92 Neothyonidium magnum 7:278 neothyonidioside from 7:278 Neozygites adjarica 28:434 Nepeta 26:172;30:268 Nepeta cataria 4:604;6:522 Nepeta hindostana 30:268 nepitrin from 30:268 Nepeta japonica 24:273 Nephtea chabroli 25:708 Nephteis 9 brasiliensis 25:875 Nephteis fasicularis 25:859;28:644 source of fasicularin 28:644 Nephthea chabrolii 21:281 Neptunia antiqua 7:4 Neptunia contraria 7:4 Nerine bowdenii 20:352 Nerinejonquilia 20:391 Nerine papyraceus 20:391 Nerine poeticus 20:391 Nerine tazetta 20:391 Nerium oleander 9:293-315;22:527 cyctotoxic agents from 9:293-315 Netschnikowia reukaufii 5:282 Neuroleaena lobata 26:808 Neurospora crassa 22:477;26:228,1016, 1128;5:277-279,8:297 Neurospora sp. 528 neurosporaxanthin from 30:528 Newbouldia leavis 22:527; 29:747 for convulsions in children 22:527
Nicandra physaloides 20:248;25:300 Nicandra steroids 20:180,182 Nicandria physaloides 20:238 Nicotiana alata 29:610 Nicotiana glauca 29:604 Nicotiana glauca x N. langsdorffii 29:609 Nicotiana glutinosa 7:101,110; 23:343;29:605 sclareol from 7:121 Nicotiana langsdorffii 29:604 Nicotiana plumbaginifolia 26:1146 Nicotiana rustica 22:742 Nicotiana setchelli 1:662 Nicotiana sylvestris 29:609 Nicotiana tabaccum L. 25:665,666 Nicotiana tabacum 1:671 ;21:661 ; 20:135;22:527;26:1145;28:400; 29:609,611 for convulsions 22:527 furostanol triglycosides 21:661 Nicotina sp. 7:124,126 nicotine synthase from 11:204, 206 Nicrophorus americanus 22:81 Nigella satvia L. 29:694 Nigroporus durus 13:305 Nigrospora oryzae 26:227 Nigrospora sphaerica 21:721 Niphates erecta 25:717 Niphates sp. 25:732 Nippostrongylus brasiliensis 22:401 ; 25:815,896 ;26:465 kalihinol Y from 26:465 Nisia nervosa 22:401 Nisia strovenosa 22:401 Nitraria alkaloids 14:731-768 synthesis of 14:731-768 Nitraria komarovii 14:762 isokomarovine from 14:762 komaroine from 14:762 komarovicine from 14:762 komarovidine from 14:762 komarovine from 14:762 komarovinine from 14:762 nitramarine from 14:762 tetrahydro-komarovinine from 14:762 tetrahydronitramarine from 14:762
1313 tetramethylene tetrahydro-bcarboline from 14:758 Nitraria schoberi 1:125 isonitrarine from 14:759 nazlinin from 14:758 nitramidine from 14:759 nitraramine from 14:750 nitrarine from 14:759 schoberine from 14:757 schoberidine from 14:759 spiroalkaloids from 14:742 Nitraria sibirica 14:541 isonitramine from 14:541 nitramine from 14:541 (-)-sibirine from 14:541 spiroalkaloids from 14:542 Nitraria sp. 14:742-765 Nitraria tangutorun 25:20 Nitzschia palea 18:698 Nitzschia pungens 21:302;26:479 Nocardia 9:433,434;25:153;26:451 Nocardia aerocolonigensis 5:55;21:263 rebeccamycin from 21:263 Nocardia aeroligenes 1:3 Nocardia brasiliensis 23:94 Nocardia interforma 10:587 Nocardia lactamdurans 22:263 Nocardia mediterranei 9:431,433,435, 440,441 ;23:54,55,57,93 rifamycin S from 12:37 rifamycin W from 12:39 Nocardia uniformis 12:118 monocyclic [3-1actams from 12:118 Nocardioides 17:285;25:719 Nocardiopsis dassonvillei 12:366,367 TAN-999 from 12:366,367 Nocardiopsis sp. 5:55 Nocardiopsis sp. K-252 1:4 Nocardiopsis sp. K-252a 12:366,368 K-252a from 12:366,368 Nocardiopsis sp. K-290 12:366,368 K-252b from 12:366,368 K-252c from 12:366,368 K-252d from 12:366,368 Nocardiopsis ~yringae 14:97,98 nocamycin from 14:97,98 Noctiluca miliaris 5:353;21:260 Noctuidae 18:772
Nodularia sp. 9:496 nodularin from 9:496 Nodularia spumigena 20:894,896;27:880 Nomamyrmex esembecki 5:250 Nopalea coccinellifera 20:734 Norcardia 10:153;21:436,442 machecin I and II from 21:486 Norcardia alba 25:162 Norcardia argentisis 17:283 Norcardia mediterranei 21:421,425 Nordostachysjatamansi DC. 22.527 Nostoc commune 21:275;26:362 Nostoc linckia 19:587;21:303;25:794 Nostoc NSW 26:95/10 26:367 Nostoc sp. 9:496-499;25:789;26:352, 366,372 Nostoc sphaericum 12:366,370 indolo [2,3 a] carbazoles from 12:366,370 Nothenia anomala 26:440 Nothenia brasiliensis 26:446, 463-465,471,483-485,487,488,492, 493 Nothenia dubius 26:432,463,471 Nothogenia fastigiata 26:1138; 30:403,408 anti-influenza activity of 30:408 xylomannans from 30:403 Notholaena affinis 5:678-680 Notholaena aschenborniana 5:676,681 Notholaena californica 5:677-679 Nothomyrmecia macrops 5:233 Notodoris citrina 17:17 Notodoris gardineri 17:18 Notoncus ectatommoides 5:224,230,254 Notopterygium incisum T. 29:696 Numida meleagrus 5:836 hemoglobin components of 5:836 Nyctanthes arbortristis 26:807 Nypa fruticans 7:176 Nysson spinosus 5:225,231,251,253 Oceanapia sagittaria 25:894 Oceanapia sp. 21:260,269;25:706, 894;28:713 dithiocyanates from 28:713 pyridoacridine alkaloids from 21:254
1314 nematocidal activity of 28:713 thiocyanatin A from 28:713 thiocyanatin B from 28:713 thiocyanatin C from 28:713 total synthesis of metabolites of 28:713 Ochrosia elliptica 6:521 epchrosine from 6:521 Ocillatoria spongeliae 21:310 Ocimum 29:579 Ocimum americanum L. 22:527 Ocimum americanum var. pilosum 30:256 vicenin-2 from 30:256 Ocimum basilicum L. 5:473,474,7:108, 109;22:392,527;27:374,376 for epilepsy 22:527 Ocimum grandiflorum 30:256 isothymusin from 30:256 Ocimum gratissimum L. 22:527 Ocimum kenyense 21:595,617 Ocimum micranthum 28:400 Ocimum sanctum L. 21:616;22:527; 29:572 Ocimum sp. 29:572 Ocimum suave 22:527 Ocotea foetens 26:850 Octocorallia 21:272 Octolasion tyrtaeum 30:828 from Lumbricidae family 30:828 Octolasium lacteum 30:828 from Lumbricidae family 30:828 Octopus vulgaris 28:647 Octotea pretiosa 19:117 Odontomachus brunneus 5:223-225,237, 254 Odontomachus clarus 5:224,228,254 Odontomachus hastatus 5:224,228,254 Odontomachus sp. 5:221,232,225,228, 237,238 Odontomachus troglodytes 5:223-225, 237,238,254 Oebalus pugnax 22:401 Oenothera biennis 23:404 Oenothera erythrosepala 23:404 Oenothera laciniata 23:404 Omphalia lapidescens 23:140 Oncomelania hupensis 23:537 Oenothera biennis 29:573,581,589 Oidiodendron griseum 28:454
Oidiodendron truncatum 28:454 Oidiodendrum griseum 28:472 terpenoid dilactones from 28:472
Oidiodendrum truncata 28:475 Olea 29:589 Olea capensis 5:514 Olea europa 3:254 Olea europaea L 5:505,515,521,523,524, 531,7:427,477;29:586;587
Olearia paniculata 25:255 Oleum chenopodii 20:12 olidago virga- aurea 29:586 Oligocerus hemorrhages 17:14 Oligonychus sp 28:423 Oligosporic actinomycete 14:98 Omphalea diandra 11:431 Omphalotus 29:271 Omphalotus illudens 26:706 Omphalotus olearius 26:483 Onchidella benneyi 17:27 Oncomelania 7:425 Oncopeltus fasciatus 22:383,393 Oncopeltus spp. 22:392 Oncosperma tigillaria 7:176 Oneostemon bojerianum 30:139 5-alkylresorcinols from 30:139
Onobrychis viciifolia 21:507 Ononis natrix 15:386 6,8-dihyd' ~xy-3-undecyl-3,4dihydrois~ coumarin from 15:386 Ononis speciosa 21:591 Onychium auratum 26:706 Onychopetalum amazonicum 2:442 Oochromonas malhamensis 2:293 Oomycete 25:299,303 Oospora astringens 24:914 oosponol from 24:914-917 Ophiarachna incrassata 7:308,309 Ophiarthrum elegans 7:308,309;15:96 Ophidiaster ophidianus 7:290;18:460 Ophiobolus vermisporis 28:125 Ophiocoma dentata 7:308,309;15:96 Ophiocoma echinata 28:721 Ophiocomina nigra 15:100 Ophioderma longicaudum 7:309,96 longicaudoside A and B from 7:94,308 Ophiodiaster ophidianus 15:46
1315
Ophiolepis superba 15:84,96 Ophiomastix annulosa 15:99 Ophiorachna incrassata 15:96 Ophiorrhiza japonica 1:125 Ophiorrhiza pumila 30:344 anthraquinones from 30:344
Ophiosparte gigas 15:99 Ophistobranch 21:317 Ophiura sarsi 15:98 cholest-5-ene-3 c~,413,21-triol-3,21disulphate from 15:98 Opisthiolopis heterophylla 9:320 Orchis morio 26:1144 Orconecttes limosus 19:628,668 Oreaster reticulatus 7:304-306,15:61 asterosaponin P~ from 7:297,300 Oricia renieri 2:121 Origanum 21:599;26:746;29:579 Origanum compactum 30:269 pyranosyl flavone from 30:269 Origanum genus 27:376 Origanum majorana 29:588 Origanum marjorana 21:599,618 Origanum syriacum 27:376 Origanum vulgare L. 21:596;22:528; 27:376;29:573,580 for epilepsy 22:528 Orina sp. 25:712 Oriola xanthornus 5:837 hemoglobin components of 5:837 Orizia latipes 24:119 Ormocarpum kirkii 22:528 for epilepsy 22:528 Ornithogalum saundersiae 21:636 Ornithopus sativus 18:514,520,523,529533 castasterone from 18:503 24-epicastasterone from 18:503 Oroidim sp. 21:270 Orophea enneandra 26:204,255 (-)-epieudesmin from 26:204 (-)-eudesmin from 26:204 (-)-phylligenin from 26:204 Oroxylum indicum 29:572,581 Orthoptera 22:371 Orthoscuticella ventricosa 17:90,95,101 Orthosiphon stamineus 29:103 Orthosiphone aristatus 24:274 Orthosphenia 18:754
Orthosphenia mexicana 7:756,758 netzahualcoyon from 7:147 orthosphenic acid from 7:147 triterpenes of 7:147 Orygyia pseudotsugata 20:124 Oryza sativa 1:529,522,20:247;23:342; 25:37729:599;605 Ostrina furnacolis 23:66 Oryzias latipes 21:365 Oscillatoria 26:352,358 Oscillatoria sp. 19:567;26:352 Oscillatoria agardhii 26:352,365 Oscillatoria cf. chalybea 26:362,373,379 Oscillatoria genera 27:879 Oscillatoria latevirens 26:364 Oscillatoria nigroviridis 18:294;19:586
Oscillatoria perornata f. Attenuata 26:373,374,379
Oscillatoria spongeliae 21:283 Oscsllatoria agardtii 25:799 Osmanthus 26:327 Osmorhiza longistylis DC 27:16 trans-anethole from 27:16 Ostertagia circumcinta 26:453,490 Ostertagia ostertagi 26:484 Ostreopsis lentcularis 26:69 Ostrinia nubilalis 26:186 Ostrya japonica 17:369 Ostrya sp. 17:369 Otanthus maritmus 21:378,381 piperide trienamide from 21:378 piperidine from 21:378 piperovatine from 21:378 Othantus moritimus 24:687 Otoba parvifolia 26:186 Ottonia anisum 24:704,710,711 Ottonia corcovadensis 24:693,694,704, 711 Ottonia vahlii 21:378 Oudemansiella mucida 3:257;22:249 Ourouparia gambir 1:25 Oxandra espinata 26:807 Oxycoryina fascicularis 25:251,727 Oxystigma buecholtzii 25:165 Oxytropis genera 27:523 Oxytropis sericea 27:516 Oxytropis sp. 27:253,444,514
Ozoroa mucronata
1316
Ozoroa mucronata 5:824,830;9:316,327; 21:591
Paccardi 26:1215 Pachastrella sp. 25:704;28:699 Pachiclavularia violacea 17:610 Pachodynerus erynnis 5:223 Pachydictyon coriaceum 6:11,70 (+)-pachydictyol A from 6:11,70 sanadaol ([3-crenutal) from 6:70 Pachygone dasycarpa 29:578 Pachygrapsus crassiples 628 Pachymeinopsis lanceolata 25:722 Pachypellina sp. 21:260;25:710 Pachyrrhizus erosus 24:779,822826;25:93 anti-feeding activity of 24:825 isoflavonoids of 24:823,824 Pachyrrhizus palmatilobis 24:822 biological activity of 24:823 chemical activity of 24:823 Pachystima 18:741 Pacifigorgia adamsii 6:10;18:614,615 pacifigorgiol from 9:254 Paecilomyces lilacinus 26:432 Paecilomyces sp. 25:725 Paecilomyces variotti 2:341;12:103;22:70 Paeon laciflora 21:584 Paeon mouton 21:584 Paeonia albiflora 22:508,528 Paeonia emodi 22:528 for epilepsy, convulsions, hysteria and hysteroepilepsy 22:528 Paeonia lactiflora 22:528 Paeonia officinalis L. 22:528 for epilepsy, hysteria and convulsions 22:528 Paeonia suffruticosa 22:528 for convulsions 22:528 Pakaraimoideae 23:531,553 Palaemon macrodactylus 22:79 Palisota ambigua 22:528 for epilepsy 22:528 Palythoa sp. 26:69 Palythoa toxica 5:390 Palythoa tuberculosa 5:390,391,393 Panagrellus redivivus 26:429,432,434, 435,438,450,455,467,473
Panagrolaimus 26:488 Panax ginseng 10:153;21:638,665; 22:96,528 ;24:146,147,154,919; 25:956;27:394,445 ;30:344 chikusetsusaponin III from 21:665 suspension cultures of 30:344 Panaxjaponicus 21:670 chikusetsusaponins from 21:670 Panax notoginseng 21:669;24:261-263; 25:476 dammarane saponins from 21:645 Panax quinquefolius L. 22:528 for convulsions 22:528 Panax sp. 21:645;27:686 saponins from 21:645 Panax zingiberensis 21:665 zingiberoside R1 from 21:665 Pancratium maritimum 20:359;26:610, 613,615-617 N, O-dimethylnorbelladine from 20:359 Pandalus sp. 19:672 Pandanus amarillifolius 21:419 bilirubin from 21:419 holomycin from 21:419 pandamarine from 21:419 Pandanus odoratissimus 26:255 Pandaros acanthifolium 5:384;25:832; 28:710 Panotima angularis 26:698 Pantoea agglomerans 28:539 Pantoneura plocamioides 25:801 Papaver oreophilum Rupr. 27:163 Papaver radicatum Rottb. 27:163 Papaver somniferum 17:633;18:45,54; 20:292;27:163 ;30:193 as analgesic 30:193 codeine from 30:193 morphine from 30:193 papaverine from 30:193 thebaine from 30:193 Papaver sp. 21:488;27:158 Papaveroideae 27:161 Papilio 26:990 Papilio xuthus 18:682 Paprika oleoresin 20:721 Paracaudina ransonetii 7:278 caudinoside A from 7:278 Paracentrotus lividus 15:104
1317
Paracoccidioides brasiliensis 5:307,323, 326;23:474 Paracoccidioides sp. 5:307,325,328 Paramecium 25:494 Paramuricea camaleon 6:72 Parancistrocerus fulvipes 5:223-225 Parancistrocerus perennis 5:224 Parancistrocerus rufovestis 5:224 Parancistrocerus sp. A 5:224 Parancistrocerus sp. B 5:224 Pararespula vulgaris 19:130 Parastichopus californicus 15:87 holotoxins A, At, B and B~ from 15:87 Parathyona sp. 7:277 parathyonoside R from 7:277 parathyonoside T from 7:277 Paratocarpus venenosa 29:773 Paratrichodorus 26:456 Paratylenchus hamatus 26:429 Paravespula vulgaris 14:526 2-methyl- 1,6-Dioxaspiro [4.5] decane from 14:526 Parinari genus 28:36 Paris polyphylla 22:528 for epilepsy 22:528 Paris vietnamiensis 21:670 steroidal glycoside from 21:670 Parkia roxburgii 24:274 Parmelia sulcata 5:313 Paromeria laevigata 24:275 Parthenim confertum 29:90 Parus gambeli 5:836 hemoglobin components of 5:836 Paspalum scrobiculatum 15:352-356 Paspalum urvillei. 22:401 Passeer domesticus 5:836 hemoglobin components of 5:836 Passiflora coerulea 29:572 Passiflora incarnata 22:528 Passiflora quadranglaris 25:205,206 Pasteurella multocida 4:196 riheptoses in 4:196 Patinopecten yessoensis 17:20;19:579; 28:653 Patiria miniata 15:55 miniatoside A and B from 15:61 patirioside A from 15:48 Patiria pectinifera 7:297,302;15:61
Patrinia intermedia 22:528 Pauridiantha lyalii 26:1036 Paxillus atrotomentosus 29:288 Paxillus atrotomentosus var.bambusinus 29:273,274 Pectinophora gossypiella 20:25,20:28 Peddiea fischeri 22:471 Pediastrum simplex 26:379 Peganum harmala L. 2:369;22:529; 26:828 for hysteria 22:529 Pelagococcus subviridis 6:135 Pelargonium fragrans 7:112 Pelargonium graveloens 7:100,101 ; 27:375 Pelargonium hortorum 21:591 Pelargonium roseum 27:377 Pelargonium sp. 7:95,96,100,112;29:582 Pelargonium xhortorum 30:146 for pest resistance 30:146 Pellia endiviifolia 2:278,279 Pellia sp. 2:90 Pellina sp. 5:419;21:260;25:709,723 Peltigera aphtosa 5:313 Penares sollasi 23:194 Penaeusjaponins 25:718 Penaeus vannamei 19:628 Penares sp. 28:460;713 as (x-glucosidase inhibitor 28:713 penarolide sulfate A from 28:713 Pencillium raistrickii H10BA2 24:933 Penicilliopsis clavariaeformis 22:649 Penicillium 25:828,901 Penicillium alladadense 5:300 Penicillium allii 21:622 Penicillium atrovenetum 19:117;23:268 Penicillium brefeldianum 11:192 Penicillium brevicompactum 5:299, 13:553;17:475;19:168 Penicillium calaviforme 5:300 Penicillium carneum 26:490 Penicillium caseiculum 13:305 Penicillium charlesii 5:296,299; 26:490,1128 Penicillium chrysogenum 5:299,300, 15:351,17:616;21:607,608;22:263; 26:1281 Penicillium citrinum 5:300,13:553, 19:168;22:251
1318
Penicillium cyclopium 28:119 Penicillium digitatum 12:103 ;25:138140,145,148,149 Penicillium erythromellis 5:300 Penicillium expansum 5:299,7:13,14; 26:228 Penicillium frequentans 4:588 Penicillium griseofulvum 9:341 ;22:80; 23:343 Penicillium hirsutum 21:622 Penicillium islandicum 5:299,300;21:413; 22:649;24:341 ;28:134 Penicillium italicum 25:150 Penicillium javanicum 5:299 Penicillium luteum 5:299 Penicillium madriti 11:198 Penicillium nigricans 26:805 Penicillium notatum 7:71;17:615;21:221; 329;25:770,780 glucose oxidase from 7:71 isocyanide xanthocillin from 21:329 xanthocillin from 21:221 Penicillium ochrochloron 5:300 Penicillium oxalicum 27:849 Penicillium palitans 4:588-590 Penicillium paraherquei 26:490;28:331 Penicillium patulum 5:300,11:198 Penicillium raistrickii 5:300;29:269 Penicillium raistrickii H10BA2 24:933, 938,939,940,944,963,965 Penicillium roqueforti 13:305; 25:129;26:490;28:331,332 microbial hydroxylation of 28:346 reaction of 28:336 spiroalkyl analogs of 28:355 structure of 28:332 Penicillium rugulosum 10:646 Penicillium scleriotorum 5:299 Penicillium sp. 5:299,301,325,326;17:475 21:198,204,224 ;24:933-972 ;25:155, 797;26:450,482 bioactive compounds of 24:933-972 taxanes from 24:942-943 taxol production of 24:933-972 Penicillium thomii 22:627 Penicillium turbatum 11:194 antibiotic A 26771B by 11:194
Penicillium urticae 21:240;22:266 patulin from 21:240 Penicillium varians 5:300 Penicillium wortmannii 21:238 wortmannin from 21:238 Penicillium zacinthae 5:300 Penicillus dumetosus 18:688 Peniophora 26:462 Peniophora filamentosa 29:265 Peniophora gigantea 29:265 Peniophora sanguinea 29:293,294 Pennisetum glaucum 29:593 Penstemon barbatus 24:799,836-837 iridoid glycosides of 24:836,837 Penstemon campanulatus 24:837-838 cytotoxic activity of 24:837 iridoid of 24:837,838 Penstemon gentianoides 24:839 Penstemon linarioi 27:837 from phenylethanoid glycoside 27:837 Penstemon rosseus 24:838 anti-fungal activity of 24:839 iridoid of 24:838 Pentaceraster alveolatus 7:290,304306;15:46,61 6-epi-nodosides from 7:34 nodososide from 7:298 Pentacta australis 15:91 DS-penaustrosides A and B from 15:91 Pentadiplandra brazzeana 27:18,19,38 brazzein from 27:18 pentadin from 27:19,38 Pentamera calcigera 28:598 from calcigeroside B 28:598 Pentapora fasciata 18:715 Pentaspadon motleyic 9:316 Pentaspadon officinalis 9:316 Peptostreptococcus sp. 25:925 Periandra dulcis Mart 15:26;27:15,16,30 periandrin from 7:142 periandrin I from 27:16,30 periandrin II from 27:16,30 periandrin III from 27:16,30 periandrin IV from 27:16,30 periandrin V from 27:16,30 Periandra mediterranea (Vell.) 15:26;27:16,30;27:15,16,30
1319
periandrin I from 27:15,30 periandrin II from 27:16,30 periandrin III from 27:16,30 periandrin IV from 27:16,30 structure of 27:31 Periconia byssoides 25:790;29:479 Perilla alcohol 19:214 Perilla frutescens 15:5;21:605-608; 27:13,20 Periplaneta 26:991 Periplaneta americana 6:538;8:182,221; 9:488-490;22:377,397 26:991 Periplaneta bunnea 8:182 Periplanetajaponica 8:182 Periploca sepium 24:273,289 Peritassa 18:754 Perna canaliculus 25:864;28:656 Persea americana 22:395;25:943; 23:342;29:593 Persea indica 26:850,851,852 cinnzeylanol from 26:850 cinnzeylanone from 26:850 epi-cinnzeylanol from 26:850 idicol from 26:850 innzeylanine from 26:850 perseanol from 26:850 ryanodanes from 26:850 ryanodol from 26:850 ryanodol- 14-monoacetate from 26:850 vignaticol from 26:850 Persea major 9:402 Persea obovatifolia 26:219 obavatifol from 26:219 obovaten from 26:219 obovatinal from 26:219 perseal A&D from 26:219 Persia thunbergii 28:419 Persoona elliptica 9:320,355 Pestaliotopsis longiseta 21:204 epiepoxydon from 21:204 (+)-harveynone from 21:204 oxysporone from 21:204 Pestalotia sp. 5:307,308 antitumor activity of 5:319 Pestalotis cryptomeriaecola 21:198 Petasites hybridus 29:87 Petchia ceylanica 5:135,140,147,149,173 Petersianthus macrocarpus 21:673
Petiveria alliacea L. 28:403 Petrocaulon purpurascens 22:348 Petrosapongia nigra 25:697 Petroselimum crispeum L. 25:666 Petroselinum sativum 22:457 apigenin-7-O-apiosyl-glucoside from 22:457 Petrosia contignata 25:713 Petrosia ficiformis 9:42 26-dehydro-25-epiaplysterol from 9:40 dihydrocalysterol from 9:37 (23R,24R)-23,24-methylenecholesterol from 9:37 Petrosia hebes 9:37 dihydrocalysterol from 9:37 hobesterol from 9:37 petrosterol from 9:37 Petrosia seriata 21:267 petrosin A,B,C from 21:267 Petrosia sp. 25:722,723 Petrosia steriata 25:694 Petrosia weinbergi 25:703;28:705,706 antiviral activity of 28:705 antiviral metabolites from 28:706 orthoesterol disulfate A from 28:705 orthoesterol disulfate B from 28:705 orthoesterol disulfate C from 28:705 weinbersterol disulfate A from 28:706 Peucedanum ostruthium (L.) 29:699 Peumus boledus 22:32,354 Peyssonelia sp. 25:694 Peziza vesiculosa 5:277;23:118,133 Pfaffia baniculata 7:135 pfaffic acid from 7:135 pfaffosides A-F from 7:135 Phaca (L.) 27:444 Phaeocystis sp. 6:135 Phaeolus vulgar& L. 19:247;21:502;659 olean- 12-ene-type triterpene saponins 21:659 Phaffia rhodozyma 7:361 (3R,3'R)-astoxanthin from 7:321 Phakellia cardus 23:216
1320
Phakellia costata 25:830;28:683 methyl sulfide group of 28:683 solid-phase synthesis of 28:683 Phakellia flabellata 21:270 Phakellia mauritiana 25:770 Phalacrocorax niger 5:837 hemoglobin components of 5:837 Phallusia manillata 10:249 Phanerochaete chrysosporium 13:309; 26:186,1014 Pharbitis purpurea 19:247 Phaseolus angularis 29:617,618 Phaseolus aureus 29:598 Phaseolus coccineus 25:93 Phaseolus lunatus 26:472;29:598 Phaseolus tribe 26:931 Phaseolus vulgaris 19:268;23:342 23:203;25:489;26:1136;29:598 23- O- [3-D-gluc op yrano syl-2-ep i-25methyldolichosteron from 18:495,522 cell suspension of 2:369 isozymes from 9:563 Phyllomedusa sauvagii 23:341 Phytophthora megasperma 23:138 Phytophthora parasitica 23:115,133 Phasianus colchius 5:836 hemoglobin components of 5:836 Pheidole pallida (minors) 5:254 2,5-dimethyl-3-ethyl-pyrazines of 5:222 Pheidole pallidula 5:235,236 Phelline comosa 3:484 Phelline spp. 3:456 Phellinus genus 19:351 Phellinus tremulae 19:171 Phenylobacterium immobile K2 4:196 triheptoses in 4:196 Phidolopora pacifica 17:92 Philanthus triangulum 5:223,224,231, 251,253 Phillyrea latifolia L. 29:685 Philodendron scandens 9:317,321 Phleba strigosozonata 29:296 Phlebia radiata 26:1013 Phlebotomus 26:783 Phleum pratense L. 27:217 Phloeodictyon 25:829;28:688
Phlomis aurea 30:265 apigenin 7-glucoside from 30:265 Phlomis betonicoides 1:666;15:20; 27:14,24 baiyunoside from 27:14,25 phlomisoside I from 27:14,25 Phlomis medicinalis 25:251 Phlomis mendocina 25:133 Phlomis spectabilis 30:265 Phlomis younghusbandii 25:257 Phoenix canariensis 27:840 Phoenix dactylifera 18:507 Phoenix paludosa 7:189 Phoenix reclinata 22:529 for epilepsy 22:529 Pholacantha synonyma 10:320 Pholagacanthus thyrsiflorus 25:251 Phoma betae 4:601 Phoma destructiva 6:555 Phoma exigna var. indoxi dabilis 6:555 Phoma sorghina 28:114 Phoma sp. 22:251,253;25:691;28:122 Phomis 26:172 Phomopsis 9:203 Phomopsis citri 15:341 Phomopsis convolvulus 15:341-345 Phomopsis foeniculi 26:1128 Phomopsis helianthi 15:341,345,346 Phomopsisjuniperovora 15:346 Phomopsis leptostromiformis 15:341,347 Phomopsis longicolla 15:341 Phomopsis oblonga 15:383,388-392 5-methylmellein from 15:385 Phomopsis oblonga 21:207 nectriapyrone from 21:207 Phomopsis paspalli 15:352 Phomopsis phaseoli 15:341 Phomopsis viticola 15:341 Phoracantha synonyma 6:542;8:222 macrocycles from 8:221 Phorbas sp. 19:601;25:759 Phormidium autumnale 26:358 Phormidium bohneri 26:365 Phormidium sp. 26:364 Phormidium tenue 25:868 Photobacterium damsela 25:719 Phryma leptostachya 26:231 (+)-haedoxan A from 26:231
1321
(+)-haedoxan D from 26:231 (-)-haedoxan D from 26:231 Phycomyces blakeslearus 18:806;25:318 (15Z)-phytoene from 7:327 Phycomyces sp. 5:276,294 Phycopsis terpnis 25:858 Phylanthus emblicata L. 22:529 Phyllanthus 29:572 Phyllanthus acuminatus 26:211 phyllanthostatin A from 26:211 Phyllanthus amarus 26:117;27:840; 29:572 phypophyllanthin from 26:217 phyllanthin from 26:217 Phyllanthus emblica 29:587 Phyllanthus emblicata L. 22:529 for epilepsy and convulsions 22:529 Phyllanthus genus 30:207,208 analgesic effect of 30:208 in treatment of hepatitis 30:207 use in kidney disturbances 30:207 use in urinary lithiasis 30:207 used in folk medicine 30:207 Phyllanthus myrtifolius 26:225 phyllamyricin E from 26:225 phyllamycin B from 26:225 phyllamyricoside A from 26:225 retrojusticidin B from 26:225 Phyllanthus niruri 5:49;17:317,343,421, 441,443;26:233,237 hyophyllanthin from 26:233 hypophyllanthin from 26:237 nirtetralin from 26:237 phyllanthin from 26:237 Phyllanthus urinaria L. 22:529 for epilepsy and convulsions in children 22:529 Phyllida pustulosa 21:366 Phyllida varicosa 21:364,366 Phyllidia bourguini 17:16 Phyllidia ocellata 25:858 Phyllidia pustulosa 25:852;28:651 4c~-isothiocyanogorgon- 11-ene from 28:651 Phyllidia sp. 6:80 2-isocyanopupukeanene from 6:80 Phyllidia varicosa 6:79,17:15 2-isocyanopupukeanene from 6:79
Phyllidiella pustulosa 21:358,359, 360,361
Phyllocladus trichomanoides 27:838 Phyllocoptruta oleivora 28:423 Phyllospongia foliascens 28:709 in serological reactions 28:709 sulfated galactolipid M-6 from 28:709 Phyllospongia sp. 25:695 Phyllostachys nigra Lodd 22:529 for convulsions in children 22:529 Phylum chordata 28:621 Physalis acnes 20:32 Physalis alkekengi 20:182,189,191, 247;22:729,740 physalin A from 20:182 physalin B from 20:182 physalin C from 20:182 physalin L from 20:189 physagulius E from 20:194 physagulins G from 20:194 zeaxanthin from 7:360 Physalis angulata 20:180,182,194,247 Physalis berghei 20:522,524 Physalis cordeana 20:470 Physalis cubeba 20:619 Physalis lancifolia 20:182 Physalis minima 20:234,238,247 A4,6-hydroxyphysalin from 20:189 Physalis mirabilis 20:859 Physalis peruviana 20:247 Physalis pubescens 20:180,189,191,247 physapubescin from 20:189 physapubenolide from 20:189 pubescenin from 20:191 Physalis vulgaris 20:845,849,851,853, 854,857 Physalis yoelii 20:521 Physarium sp. 5:275 Physarum polycephalum 5:275,276; 28:133 ;29:223,239 all-trans-N-[ 11-(2-acetylamino-3hydroxyphenyl)2,4,6,8,10undecapentaenoyl]-S-glutamine from 29:240 as myxoamoebae 29:243 chemical constituents of 29:239 chrysophysarin A from 29:242 constituents of 29:243
1322
cultivation of 29:247 DNA polymerase activity of 29:244 enantioselective synthesis of 29:244 isomers of 29:245 lysophosphatidic acid from 29:243 metabolites of 29:242 pigments of 29:241 plasmodial constituents of 29:239 polycephalins from 29:242 spore germination by 29:250 sterol contents of 29:240,243 synthetic derivatives of 246 Phytoalexin rishitin 25:319 Phytolacca acinosa 7:144,145 triterpenoids of 7:144,145 Phytolacca americana 13:655 Phytolacca dodecandra 21:660;28:400 tick toxicity of 28:400 Phytolacca dodecandra 7:427,428,430, 434 Phytophthora 25:303,395,396 Phytophthora cinnamomi 21:190, 199,223,233 Phytophthora elicitins 25:395 Phytophthora infestans 5:276;21:181; 26:936 Phytophthora megasperma 25:303,396 Phytophthora nicotianae var. parasitica 26:404 Phytophthora nicotianae var. parasitica 26:404,418 Phytophthora parasitica 5:607 Phytophthora sojae 22:498 Phytophthora sp. 5:276;7:183;9:203; 21:197,221 Phytoxin pisatin 25:322 Pica pica 5:836 hemoglobin components of 5:836 Picea 27:372;29:589 Picea abies (L.) Karl. 18:498;25:666; 27:370,385 Picea cocos 29:99 Picea glehni 29:99,100 Picea sitchenesi 19:247 Picha strasssburgensis 5:287 Pichia angusta 21:391 Pichia anomala IFM 47182 28:476
Pichia bovis 5:287 Pichia farinosa 5:283 Pichia ohmeri 5:283 Pichia pastoris 5:283;26:1263,1269,1288 Pichia sp. 5:281,297 Pichia terricola 1:706 reduction with 1:706 Pichia totetana 5:283 Pichia vanriji 5:283 Picicularia oryzae 5:287,598 Picnomon acarna L. Cass. 22:529 Picrasma ailanthoides 7:369,385;23:291 Picrasma quassioides 1:126;23:291 Picrolemma pseudocoffea 7:369,381 Pieris brassicae 26:702 Pieris rapae 18:771 ;26:439 Pierreodendrom kerstingii 7:369,379,398 Pilocarpusjaborandi 27:522 Pilocarpus sp. 21:488 Pimenta dioica 28:398,403 Pimenta racemosa 29:99 Pimpinella anisum 5:473;28:427 Pimpinella sp. 28:431 ( 1E)-propenyl-4-hydroxybenzene 28:from 28:431 against Typhlodromus telarius 28:431 epoxy-anoltiglate from 28:431 epoxy-seudoisoeugenolisobutyrate 28:from 28:431 epoxy-pseudoisoeugenoltiglate 28:from 28:431 isoeugenolisobutyrate from 28:431 phenylpropanoids from 28:431 pseudoisoeugenolisobutyrate 28:from 28:431 Pinellia ternata 24:272 Pinna muricata 19:616;25:871;28:657 Pinns strobus 25:245 Pinus 26:905 Pinus canarienis 26:859 Pinus caribaca 25:151 Pinus densiflora 26:471 Pinus flexilis 26:887;27:853 Pinus halepensis 28:420 Pinus koraensis 5:701,702 Pinus maritima 29:583 Pinus massoniana 26:472,474 Pinus nigra 25:249;28:420
1323
Pinus palustris 25:151 Pinus parviflora 30:407 acidic polysaccharide from 30:407 Pinuspeuce 27:370, 372 Pinus pinaster 28:420 Pinus pinea 28:420 Pinus radiata 7:99,101,105,106,108,109 Pinus silvestris 17:604,19:247;23:342 Pinus sp. 7:106;21:501;27:372 Pinus sylvestris 25:249,666;27:370 Pinus thunbergii 19:247,18:498; 21:417; 26:471 Piophocarpus tetragonolobus 19:247 Piper acutisleginum 24:693,695 Piper aduncum 24:699,711,712 Piper amalago 24:685,687,688,691-694, 699-702,704,710,712 Piper argyophyllum 24:686,695 Pipet" attenuatum 24:693,695,697 Piper aurantiacum 24:699,709,710 Piper betle 24:693,695,710;26:243,469 methylpiperbetol from 26:243 piperbetol from 26:243 piperol A&B from 26:243 Piper brachystachyum 24:688,692,697 Piper callosum 21:378;24:692,693, 704,710,711 pipercallosine from 21:379 piperovatine from 21:379 Piper chaba 24:692,709,710,711 Piper clusii 20:619 Piper decurrens 26:232 Piper demeraranum 24:700 Piperfutokadsura 24:695;26:240 kadsurenin from 26:240 kadsurenin H from 26:240 Piper guineense 17:317;21:378;24:684, 686,692-698,703-705,709,711, 712,716,717 chavicine from 21:379 guineensine from 21:379 isochavicine from 21:379 isopiperine from 21:379 piperine from 21:379 Piper kadsura 26:240 denudatin 26:240 Piper khaslana 24:693
Piper longum 21:379; 22:509,529;24:686,691, 692,695-697,699,702,709,710 Piper mantii 24:697 Piper marginatum Jacq. 27:16 trans-anethole from 27:16 Piper maritmus 24:687-689,695,705,709, 710,712 Piper methysticum 13:660 kawain from 13:660 Piper methysticum 22:508,530; 24:711,799 Piper nigrum 10:152;21:379;22:530; 24:273,683,686,687,689,691-697, 701,704;26:819 piperine from 26:819 Piper novae-hollandiae 24:686,692,693, 695,711,712 Piper oftqcinarum 10:151 ;24:689,695, 697,709,710 Piper ovatum 21:378;24:684,704,710 Piper peepuloides 24:707,709 Piper puberulum 26:243 puberulin A&C from 26:243 Piper regnellii 22:358 Piper retrofractum 22:530 Piper ridley 24:697,698,705,707 Piper sarmentosum 21:378;24:686,687, 697,702,709-712,731 ;29:684 Piper schmitii 24:700 Piper sp. 24:683-738 Piper sumatranum 17:348 Piper sylvaticum 21:378;24:686,695, 709,712 Piper trichostachyon 21:378;24:687,694, 696,697 trichostachine from 379 trichonine from 21:379 Piper umbelata 22:358 Piper wightii 24:700 Piptocalyx moorie Oliv. 4:709 Piqueria trinervia 24:779,817-819; 28:404 diterpenes of 24:817 herbicidal activity of 24:819 monoterpenes of 24:817 toxicity to gravid female ticks 28:404 Piricularia oryzae 2:434;23:112;26:1210
1324
Pisaster brevispinus 15:61 pisasteroside A from 15:61 Pisaster giganteus 15:66 Pisaster ochraceus 15:61 pisasteroside A from 15:61 Pisidium guajava hemoglobin components of 5:837 Pissodes 27:384 Pistachia vera 9:316,327,339 Pistacia chinensis 28:234 Pistacia integerrima 21:582;22:118 Pistacia lentiscus 29:580 Pisum sativum 17:402,18:708,710; 19:247;25:93,417;26:832,1263; 29:599,605 Pithecellobium dulce 21.'657 Pithecolobium saman. 22:530 Pithomyces sp. 25:172 Pituranthus tortuosus 27:687 Pityrophthorus pityographus 1:692; 25:144 Pityrosporium sp. 13:309 Piulella xylostella 23:66 Plactranthus caninus 7:119 Plagiochila 21:281 Plagiochila acanthophylla 2:81,280 Plagiochila hattoriana 2:280 Plagiochila yokogurensis 2:280 Plakellia sp. 25:715 Plakinastrella sp. 26:73 Plakortis 23:201;26:492 Plakortis angulospiculatus 18:719 Plakortis halichondroides 18:719 Plakortis lita 5:353,354;18:718,719; 23:201;25:724 Planaxis sulcatus 17:22,28 Plankortis simplex 25:721 Planotortaix excessan 7:193 Planotortaix leafroller 7:193 Plantago major 29:84 Plasmodia 25:348 Plasmodium 25:327;26:779-781,797,798, 800,802-804,815,825,1030,1035, 1036,1063 Plasmodium falciparum 29:569 Plasmodium genus 19:587 Plasmodium berghei 7:391,394,395; 25:333,338,341 ;26:1063 Plasmodium CDPK 25:544
Plasmodium chabaudi 26:789 Plasmodium falciparum 7:391,392-394, 424;13:656;20:516,517,519-522; 21:744 ;22:145 ;23:238,819;25:328, 330-332,334,336,338,340-342,345, 348,350-352,359,527,814;26:230, 231,456,466,781-783,788,789,797, 800,801,804,805,808,811,813,815, 816,819,820,822-824,828,837-839, 1037,1063;28:148;29:569 antimalarial activity of 7:424 Plasmodium lophurae 26:803 Plasmodium malariae 20:516,517; 25:328;26:781,837 Plasmodium ovale 20:516;26:781,789 Plasmodium strains 30:694 against human adenocarcinoma cell line HT-29 30:694 Plasmodium vivax 20:516;25:328; 26:781,783,789,803,837 Plasmodium yoelii 21:744;26:789,828 Plasmopara viticola 27:768 Platycarya 26:905 Platycarya genera 27:755 Platycarya strobilacea 26:899 Platycodi radix 30:89,91 effects on liver triacylglycerol 30:89 effects on liver weight 30:89 effects on plasma triacylglycerol level 30:90 effects on total cholesterol 30:89 Platycodon grandiflorum 22:97 Platystemon genera 27:163 Plectranthus 25:238 Pleiocarpa mutica 1:124 Pleiocarpa talbotii 13:397,424 Pleisopermium alatum 13:351,20:497 Pleraplysilla spinifera 6:72 spiniferin 1 from 6:72 Pleurobranchus forskalii 25:887;28:642 Pleuronectes platessa 25:131 Pleurotus glabellatus 25:131 Pleurotus ostreatus 5:288;23:115,119; 26:111 Pleurozia acinosa 25:252 Plexaura homomalla 9:570 Plocamium 25:701 Plocamium cartilagineum 18:714;25:701
1325
Plocamium castatum 25:701,781 Plocamium coccineum 17:9 Plucchea sagittalis 22:349
Podochaenium eminens 7:416 Podophyllum bankakri 26:149 Podophyilum emodi 17:341 ;26:149,153,
5,3 ',4 '-trihydroxy-3,6,7-trihydroxy-3,6,4 '- trimetho xyflavone from 22:349 5,7,3'-trihydroxy-3,6,4' trimeth oxy-flavone from 22:349 5,7,3 ',4'-tetrahydoxy-3,6,8trimethoxy ftavone from 22:349 Pluchea arguta 5:202,204;9:65;24:112 Pluchea lanceolata 22:117 Pluchea sp. 9:65-68 sesquiterpenes from 9:65-68 Plumbago scandens 2:225 Plumbago zeylanica 2:215,226;22:530 quinones of 2:212-231 Pneumocandins 22:69 Pneumocystis carinii 2:421 ;22:248; 26:804,835 Poa annua L. 27:217 Secale cereale 27:217 Triticum aestivum 27:217 Dicentra spectabilis 27:158,163 Podachaenium eminens 29:89 Podocarpus dacrydioides 14:449,450 (-)-selin- 11-en-4c~-ol from 14:449,450 Podocarpus elatus 29:10 Podocarpus ferrugineus 25:246 Podocarpus gracilor 28:462 Podocarpus hallii 28:462 Podocarpus macrophylus 28:462 Podocarpus milanjianus 28:464 Podocarpus nagi 21:602;28:464;29:579 Podocarpus nakaii 28:463;29:10 Podocarpus neriifolius 28:463 Podocarpus nivalis 28:458 Podocarpus nubigena 28:463 Podocarpus philippinensis 28:462 Podocarpus polystachyus 28:462 Podocarpus purdeanus 28:458 Podocarpus saligna 28:466 Podocappus sellowii 28:464 Podocarpus sp. 28:453 Podocarpus totara 21:602;28:454 podolactones from 28:454 totarol from 21:602 Podocarpus urbanii 28:459
154,156,158,171,173,178 podorhizol from 18:556 Podophyllum hexandrum 5:474,477,480, 482,483,485-497,488,493,494;26:227 4 '-O-de me thl de hdropodop h yllotoxin from 26:227 picropodophyllone from 26:227 Podophyllum peltatum 5:480,483-485, 493 ;17:341 ;18:557 ;24:269,774; 26:149-152,158,171-178;29:578 podorhizol from 18:556,557 podophyllotoxin derivatives of 7:416 Podophyllum sp. 5:461,477,481,483,485, 489,493 Poecillastra sp. 19:580;25:731 Pogonomyrmex barbatus 5:250 Pogonopus speciosus 9:401 Pogonopus tubulosus 9:401 Pogostemom cablin 25:171 Pogostemon purpurascens 5:681 Pogostemon sp. 8:423 (-)-patchoulol from 8:423 (-)-seychellen from 8:423 Polyalthia excessa 28:416 Polyalthia longifolia 28:416 Polyalthia viriclis 22:400 Polyandrocarpa sp. 10:248 Polycarpa 25:836 Polycarpa aurata 23:260;25:706,836; 28:640 Polycarpa auzata 28:640 Polycarpa clavata 28:640 Polycavernosa tsudai 19:570 Polycitor adriaticus 28:642 Polycitor sp. 25:834 Polycitorella mariae 25:837;28:634 citorellamine from 28:634 Polyclinum planum 28:643 polyclinal from 28:643 Polyfibro~pongia australis 25:694 Polyfibrospongia sp. 19:577 Polygala fruticosa 7:415;23:342 Polygala polygama 17:34 ! Polygala senega 21:666 senegasaponins from 21:666
1326
Polygnum cuspidatum 27:405 for hyperlipidaemia 27:405 Polygonati rhizoma 21:668 14a-OH-diosgenin from 21:668 Polygonum auberti 22:607,608,609,613, 614,615,621 Polygonum avaculare 22:614,632 Polygonum bistorta 22:118,119,632 Polygonum caepitosum 22:633 Polygonum chinense 22:614 Polygonum conspicum 22:632,634 Polygonum coriavium 22:614 Polygonum culiinerve 22:609 Polygonum cuspidatum 22.607,608,609, 611,633,637 Polygonum cuspidatum 27:854;30:340 anthraquinone emodin from 30:340 Polygonum debile 22:632 Polygonum dumetorum 22:633 Polygonum ellipticum 22:610 Polygonumfalcatum 22:610 Polygonumfilliforme 22:615,632,634 Polygonum glabrum 22:614 Polygonum hydropiper 7:100,101,103,
110,121;17:237;21:608;22:612,614,
633,634,635 ;29:87; sesquiterpene from 1:701,702 Polygonumjaponicum 22:633 for convulsions 22:530 Polygonum lapathifolium 22:633 Polygonum longisetum 22:633 Polygonum maackianum 22:632 Polygonum multiflorum 22:610,633 Polygonum nakai 22:633 Polygonum napalense 22:632,634 Polygonum nodosum 7:427;22:614,615 Polygonum orientale L. 22:632; 29:579,580 Polygonum panjutinii 22:611 Polygonum pensylvanicum 27:837 Polygonum perfoliatum 22:632 Polygonum persicaria 22:633 Polygonum plebejum 22:612 Polygonum pubescens 22:633 Polygonum sachalinense 22:608,609,610, 620,633 Polygonum sagittatum L. var. sieboldi 22:632
Polygonum senegalense 7:427;22:614 Polygonum senficosum 22:632 Polygonum sp. 22:460;27:405; 28:579;29:581
Polygonum suffultum 22:632 Polygonum tenuicale 22:632 Polygonum thunbergii 22:466,632 Polygonum tinctorium 22:612,633 Polygonum virginianum 22:615 Polygonum viviparum 22:632 Polygonum werichii 22:633 Polygorium hydropiper 29:87 Polygraphus poligraphus 27:370 Polygyala gazensis 26:204 eudesmin from 26:204 kobusin from 26:204 magnolin from 26:204 yangambin from 26:204 Polymastia boletiformis 25:704;28:704 Polymastia sp. 18:716 Polyodiumformosanum 24:256 Polyodium nipponica 24:256 Polyodium vulgare 24:256 Polyorchis penicillans 9:493,494 Polyozellus multiplex 29:277 Polypodium glycyrrhiza 15:28;21:674; 27:16,32 polypodoside A from 27:16,32 polypodoside B from 27:16,32 steroidal saponin from 21:674 structure of 27:32 Polypodium vulgare L. 15:28;27:16; 29:10 osladin from 27:16 Polyponus circinatus 5:288,308 Polyporus betulinus 5:288 Polyporusfomentarius 5:289 Polyporus giganteus 5:288 Polyporus igniarius 5:289 Polyporus leucomelas 29:277 Polyporus nidulans 29:265 Polyporus rutilans 29:265 Polyporus tumulosus 5:288,290 Polyscias 7:435 Polyscias dichroostachya 21:660 Polysiphonia lanosa 4:712 Polysyncaraton lithostrotum 25:837; 28:645 Polytomella coeca 2:294
1327
Poncirus trifoliata 29:579 Ponera pennsylvanica 5:224,230,254 Pongamia glabra 22:530;29:771 for epilepsy 22:530 Pongamia pinnata 28:401 Populus balsamifera 29:605 Populus deltoides 29:605 Populus maximowiczii 20:627 Populus tremuloides 26:358;29:605 Populus trichocarpa 29:605 Porania pulvillus 7:298 poranoside A from 7:299,301 Poraster superbus 7:299 Porella cordeana 20:469 Porella perrottetian 2:280 Porella sp 2:90 Poria cocos Wolf 5:288;22:120;25:956 Porlieria chilensis 22:352;26:249 dihydroguaiaretic acid from 26:249 guayacasin from 22:352;26:249 isopregnomisin from 22:352; 26:249 Poronia piliformis 21:197 Porphyromonas gingivalis 23:536 Porteresia coarctata 7:189 Porthetria dispar 19:481 Portieria hornemannii 23:342;25:702, 767;26:809 Portulaca oleracea 22:360 [3-carotene from 22:360 Potamogeton sp. 26:361 Potentilla tormentilla 21:542 Pothomorphe peltata 22:356 uses of 22:356 Pothomorphe spp. 22:357 Pothomorphe umhellata 22:356 Pothos scandens L. 22:530 for convulsions 22:530 Potomogeton nodosus 25:260 Potyalthia macropoda 25:260 Pratylenchus 26:432 Pratylenchus coffeae 26:436 Pratylenchus curvitus 26:477 Pratylenchus neglectus 26:464 Pratylenchus penetrans 26:429,436438,449,473,477,481 Pratylensus scribneri 26:472 Premna oligotricha 25:257
Preussia isomera 21:209 thepreussomerins from 21:209 Priano melanos 25:822 Priano sp. 25:760,822 Prianos melanos 28:685 Prianos sp. 9:15 muqubilin from 9:15 Primula denticulata 5:211 Primula obconica 7:427 Primula viscosa 20:740 Pristimera grahamii 23:659 Pristimeria indica 30:664 celastrol from 30:664 pristimerin from 30:664 Procambarus bouvieri 19:665 Procambarus clarkii 19:627 Proleus mirabilis 25:259 Propionibacterium acnes 25:463,471, 28:534 mononuclear cell infiltration induced by 25:463 Propionibacterium shemanii 9:598,600604; 11 : 182 Prorhinotermes simplex 19:118 Prorocentrum 27:875 Prorocentrum lima Prorocentrum lima 5:384,17:20,19:617; 21:301 Prorocentrum maculosum 21:301 Prorocentrum sp. 21:301 Proserpinaca palustris 26:359 Prosopis chilensis 28:424 Prosopis glandulosa 29:580 Prosopisjuliflora 5:211 ;9:68-73;29:605 alkaloids from 9:70-73,290 terpenoid diketone from 9:68,69 Prosopis sp. 29:420 Proteus 12:63 Proteus ganera 29:311 Proteus mirabilis 12:400;20:712,837,840, 842,853,855,858 Proteus mirabilis 22:627;26:402,1155 Proteus vulgaris 9:308;12:103,400; 20:831,837,839,840,859,879;22:627 Protoreaster nodosus 7:290,304-306; 15:46,60 5ot-cholestan-3 [3,6c~,8,15(x, 16[3,25hexol from 15:77 nodosocide from 7:295
1328 Prunella vulgaris 29:588;30:401 antiviral activity of 30:401 Prunus avium 23:746 Prunus cerasus 20:721;23:746 Prunus domestica 21:506;23:750 Prunus ovium 21:498 Prunus persica 21:503 Prunus sp. 26:1157;29:577 Prymnerium parvum 25:794 Psalliota bispora 13:310,304 Psalliota campestris 5:289 Psammaplysilla 28:693 Psammaplysilla purpurea 25:719;28:693 antimicrobial activity of 28:693 as tyrosine kinase inhibitor 28:693 presammaplin A from 28:693 psammaplin B from 28:693 psammaplin C from 28:693 psammaplin D from 28:693 Psammaplysilla sp. 25:833 Psathyrotes ramosissima 7:427 Psendomonas aureginosa 20:712 Pseudaxinyssa 9:38;28:665 c~,~0-bis-isothiocyanates of 28:665 Fijian species of 28:65 ot-isothiocyano-o- formyl analogues 28:of 28:665 Pseudaxinyssa pitys 21:356;25:854; 28:659 farnesyl isothioycyanate from 28:659 Pseudaxinyssa sp. 25:857 Pseudoarachniotus roseus 21:389 aranorosin from 21:389 Pseudobersana mossambicensis 20:478 bioactive steroids from 20:476 Pseudoceratina purpurea 25:720,774,784 Pseudoceratina verrucosa 25:712 Pseudodistoma arborescens 23:264 Pseudodistoma aurum 25:782 Pseudodistoma kanoka 10:249;23:185 Pseudodoynerus quadrisectus 5:224,232 Pseudolarin kaempferi 21:654;23:342 Pseudomanas syringae 26:583,590592,594,595,598,599,607 Pseudomonas 5:434;9:37;18:429,430; 21:185-187;22:81;25: 145,146,148,
152,153,155,929;26:69,582,584,
588,597,617,969, 1124;1134
papakusterol (glaucasterol) from 9:37 for enantioselective hydrolysis 12:337 Pseudomonas aerginosa 1:370,377; 3:302 ;5:434 ;9:308,537,540,553,555; 12:63,103,401 ;14:144,236; 19:601; 21:610;23:41,235 ;25:133,257,258, 259,394,828;26:330,331,365,402, 1151;30:739 antibacterial activity against 30:739 antifungal activity against 30:739 Pseudomonas alginate 26:1151 Pseudomonas amygdali 26:583,587,590, 599 Pseudomonas aureofanines 9:527 Pseudomonas bromopseudilin 21:298 Pseudomonas caryophylli 26:594 Pseudomonas cepacia 4:432;21:205 Pseudomonas cepacia lipase 30:473 in isopropenyl acetate 30:473 Pseudomonas chloroaphis 9:537 Pseudomonas ciccaronei bacteriocins 26:595,599 Pseudomonas cichoriae 9:537 Pseudomonas citronellolis 25:132,133, 165 Pseudomonas clavata 25:836 Pseudomonas convexa 25."133 Pseudomonas coriacea 12:294 Pseudomonas denitrificans 9:600,603, 604,606 Pseudomonas diminuta 26:1155 Pseudomonas eruciviae 25."168 Pseudomonas fluoescens 3:263;9:537; 10:78;21:186,296;25:152,394 ;26:78, 333,334 Pseudomonas fluorescens lipase 1:685;13:54,55 Pseudomonas genus 19:791 Pseudomonas incognita 25:133,140, 141,147 Pseudomonas iodina 27:219 Pseudomonas lipase PSL 13:55 Pseudomonas magnesiorubra 28:115 Pseudomonas maltophilia 4:432 Pseudomonas medicinalis 25:257 Pseudomonas morganii 5:434
1329
Pseudomonas perolens 13:320 Pseudomonas pseudomallei 25. 140 Pseudomonas putida 4:647;8:296,298, 303,305,309 ;9: 537;13:58,299;18:430; 25:131,156,661 Pseudomonas sorghi 9:220 Pseudomonas striiformis 9:220 Pseudomonas syringae 4:590;9:537; 25.'399,394,398 Pseudomonas syringae pv. Maculicola 26:593,933 Pseudomonas taetrolens 13:320 Pseudomyrmecine sp. 6:421,422 Pseudo-nitzschia multiseries 25.'729 Pseudophryne coriacea 725 Pseudophryne genus 19:52 Pseudophryne guentheri 726 Pseudophryne occidentalis 18:726 Pseudoplexaura crucis 8:20 Pseudoplexaura flagellosa 8:20
Pseudoplexaura porosa (Plexaura crassa)
8:20 crassin acetate from 8:20 Pseudoplexaura wagenaari 8:20 crassin acetate from 8:20 Pseudopterogorgia 23:153 Pseudopterogorgia acerosa 23:154,164, 170,175 Pseudopterogorgia americana 6:18,27 21:313 ;23:154,160 (-)-[3-gorgonene from 6:18,27 Pseudopterogorgia bipinnata 23:154, 175,178 Pseudopterogorgia elisabethae 15:259; 23:154 ;25.690;29:689 pseudopterosins A-D 6:74 Pseudopterogorgia hummelinkii 23:154 Pseudopterogorgia kallos 23:154,175 Pseudopterogorgia rigida 23:154,164,181 Pseudopterogorgia sp. 23:179 biological activity of 179 Pseudostichopus trachus 15:94 pseudostichoposide A from 15:94 Pseudosuberites hyalinus 18:696 Pseudotsuga menziesii 27:837,838 Pseudoxanthoma elasticum 26:675
Psiadia 7:411 Psiadia trinervia 7:411-413;23:342 Psidium guajava 21:581;22:530;29:579
Psidium guianense 21:614 Psidium guyava L. 22:530 for epilepsy and convulsions in children 22:530 Psilocybe mexicana 25:531 Psittacula krameri 5:837 hemoglobin components of 5:837 Psolus fabricii 7:278,279;15:89;28:598 Psolus patagonicus 28:597 Psolus tabricci 25:701 Psophocarpus tetragonolobus 29:605 Psoralea corylifolia L. 29:705 Psoralea glandulosa 22:354 Psoriasis 9:514,517
Psoroptes 28:416 Psoroptes cuniculi 21:612;28:415 Psoroptes mites 28:410
in bull fattening management 28:410 spread of 28:410 Psorospermum febrifugum 7:417-420,424 psoprspermin from 13:368 Psorosporum 22:580 Psychotria campoutans 26:804 Psychotria curviflora 22:530 for convulsions 22:530 Psycotria colorata 30:205 to relieve abdominal pain 30:205 use in earache 30:205 Psycotria sp. 30:205 trimmer hodgkinsine from 30:205 Ptareolidiaianthina 23:178 Pteridium aquilinum 6:194 Pteridium aquilinum var. caudatum 26:687,690-692,695,696,698,699, 702,703,720,722,724,725,727 Pteridium arachnoideum 26:699 Pteridium esculentum 26:699 Pteridium laliusculum 26:690,702 Pteridium sp. 26:685-692, 694-702,704,720,721,723,724,726 Pteridophyllum genera 27:163 Pteris aquilina 26:691 Pteris cretica 26:745 Pterocarpus santalinus 20:774 Pterocarya paliurus Batal 21:674;27:16 pterocaryoside A from 27:16 pterocaryoside B from 27:16 secodammarane from 21:674
1330
Pterocaulon plystachium 22:347 rhamnetin from 22:347 Pterogorgia citrina 17:99 Pterogyne nitenes 20:489 guanidine alkaloids from 20:488 Pterosin F 26:700,701,702 Ptilocaulis spiculifer 28:690 alkyl sulfate from 28:690 dakaramine from 28:690 Ptilometra sp. 28:719 anthraquinones from 28:719 Ptilosarcus gurney 21:252 ptilosarcone from 21:252 Ptilota filicina 25:718 Ptychodiscus brevis 6:135 Ptygonum bistorta 22:118 Puccinia 9:203,220,222 Puccinia antirrhini 9:220 Puccinia arachidis 9:220 Puccinia coronata 9:220,226 Puccinia coronata fsp. avenae 9:220223,228 Puccinia coronata fsp. festucae 9:221 Puccinia graminis 9:220,226 Puccinia graminis fsp. tritici 9:220,221, 228 Puccinia helianthi 9:220 Puccinia podophylli 26:176 Pueraria lobata 25:93 Pueraria thomsonii 25:93 Pulchea indica 7:185 Pulcherricium caeruleum 29:284 Pulsatilla chinensis 29:652,653 Punctularia atropur- purascens 29:286 Punica granatum L, 21:504;22:530; 29:582,584 for epilepsy 22:530 Purpurea glycoside A 15:362 Purpurea glycoside B 15:362 Putterlickia verrucosa 23:70 Puwainaphycin C 25:793,794 Pycnanthus angolensis 26:219,473 Pycnonotus cafer 5:837 hemoglobin components of 5:837 Pycnonotusjocosus 5:837 hemoglobin components of 5:837 Pycnopodia heliantoides 15:46 pycnopodiosides A,B and C from 15:61
Pycnoporus 26:1013 Pycnoporus cinnabarinus 26:1010-1016 Pycnoporus coccineus 26:1012 Pycnoporus sanguineus 26:1012 Pyrenophora avenae 19:154 Pyricularia oryzae 1:404;4:598;12:401; 15:385;22:398,273;28:114 Pyricularia sp 16:302 Pyrrhocoris apterus 22:382,383,392 Pyrus 29:588 Pyrus communis 23:750;26:592;29:588 Pythium acanthicum 5:276 Pythium middletoni 21:199 Pythium sp. 5:276;21:197,221 Pythium ultimum 21:186,187,211,219221,223,229,238;22:482 Pythium ultimum 7:183,190 Pytophthora cinnamomi 5:276 Pyura sacciformis 23:257 Quassi excelsia 7:124 Quassia amara 7:392 quassin from 7:392 Quassia indica 23:296 Quassia simarouba 28:400 Quercus aliena 23:417 Quercus faginea 27:663 Quercus genera 27:755 Quercus ilex subsp, ballota 27:663 Quercus imbricaria 21:657 Quercus infectoria 22:530 for epilepsy 22:530 Quercus pedunculata 29:589 Quercus phillyraeoides 23:403 Quercus sp. 21:502 Quercus tinctoria 29:581 Quillaia 26:55 Quillaja saponaria 21:646,648;24:131, 133,138,139,144,149,152,155-158, 167,171;26:54 Quisqualis indica 26:476 Rabdosia amethystoides 15:167 Rabdosia diterpenoids 15:112 classification of 15:112 Rabdosia eriocalyx 15:176 Rabdosia gerardiana 15:167
1331
Rabdosia glutinosa 15:167 Rabdosia japonica 15:111 Rabdosia laxiflora 15:176 Rabdosia lophanthoides 15:167 Rabdosia macrophylla 15:167 Rabdosia occidentalis 15:176 Rabdosia parvifolia 15:167 Rabdosia shikokiana 15:162,176 rabdoepigibberellolide from 15:112 Rabdosia sp. 15:111-185 diterpenoids from 15:111-185 Rabdosia stracheyl 15:167 Rabdosia trichocarpa 15:135,176 Radermachera xylocarpa 29:722 Radopholus similis 25:662 Radopholus similis 26:474 Radula complanata 2:283 Radula kojana 2:283 Radula perrottetii 2:283 Ralstonia solanacearum 26:933 Ramalina usnea 5:310,313 Randia dumetorum 21:660 Randia esculenta 22:530 for convulsions 22:530 Randia siamensis 21:673 Ranunculaceae 25:180;27:161,164,754 Rapanea laetevirens 9:321 Rapanea melanophloeos 21:660,662 Rapanea umbellate 30:657 24-(E)- 3 -o xo-dammara-20,24-dien26-al from 30:657 Raphanus sativus L. 18:507;19:247; 23:342,26:1075 homoteasterone from 18:507 Raphisia pallida 25:705 Raspaciona aculeata 25:700 Raspacionins 25:700,701 Ratibida columnifera 19:771 Rauwolfia alkaloids 14:553,19:748 Rauwolfia heterophylla 1:125 Rauwolfia nitida 1:125,126 Rauwolfia sellowii 1:125 Rauwolfia serpentina 1:125,126,283,390; 2:369;13:629,660;19:748; 22:531; 26:1060;29:362 deserpidine from 8:283 for epilepsy 22:531 reserpine from 8:283
Rauwolfia suaveolens 13:390,411 Rauwolfia tetraphylla 1:126 Rauwolfia verticillata 13:391 Rauwolfia vomitoria L. 1:125,427;22:531 for epilepsy 22:531
Ravensara aromatica 27:377 Reidispongia coerulea 26:1207,1208 Reinera sp. 25:723 related compounds of 25:538
Renealmia alpinia 25:266 Reniera sarai 22:30 Reniera sp. 21:266 1,6-D imeth yl- 7- metho x y- 5,8dihydroisoquino-line-5,8-dione from 21:263,266 renierone from 21:265 Resda luteola 26:632 Reynoutnajaponica 22:608 Reynoutriajaponica var. typica 24:273 Rhabdastrella sp. 21:273 Rhabditis sp. 26:432,488 Rhamnaceae 27:3 Rhamnus catartica 22:583 Rhamnus frangula 22:583 Rhamnus purshiana 22:583 Rhazia stricta 5:135,140-144,150,152, 153,165,167,169,176,178;29:362 Rheedia gardneriana 30:207 antinocicieptive effect of 30:207 Rheedia madrunno 22:658 Rheum emodi T. 30:327 physcion from 30:327 Rheum palmatum 17:421,439; 27:849,850;29:579 Rheum spp. 29:589 Rhinacanthus nasutus 26:226;29:747 rhinacanthin E&F from 26:226 Rhinoclaviella sp. 26:673 Rhipicephalus appendiculatus 28:396 Rhipicephalus evertsi 28:396 Rhipicephalus genera 28:404 Rhipicephalus haemaphysaloides 28:405 Rhipicephalus sanguineus 28:400 Rhipicephalus spp. 28:407 Rhipocephalus phoenix 18:689 Rhizobia 25:395 Rhizobium- 22:345 Rhizobium meliloti 25:395 Rhizobium symbiosis 25:659
1332
Rhizoctonia leguminicola 7:11 ;19:468; 27:254,255,515 (-)-( 1S,2R,8aS)-indolizidine- 1,2diol from 12:303 slaframine from 12:306 (-)-swainsonine from 12:313 Rhizoctonia solani 7:190;13:233,234 21:182,187,197,199,202,205,219, 220,229,213,223,238;22:459,489, 499;26:404, Rhizophora apiculata 7:180-182,189, 194,195 Rhizophora mangle 7:175 Rhizophora mucronata 7:176,180, 188,189,192,194,195 Rhizophora sp. 7:176 Rhizophora stylosa 7:179-181,193 Rhizopogon 29:271 Rhizopus arrhizus 17:629;23:20,23,25 Rhizopus delemar 2:322,341 Rhizopus nigricans 17:629;24:74,76; 25:253,261,318 Rhizopus niveus 2:322,341 glucoamylase from 7:49 Rhizopus oligosporus 26:100 7 Rhizopus sp. 2:322,323,276 glucoamylase from 2:341 Rhodiola sachalinensis 29:590 Rhodiola sacra 29:590 Rhodium prolixus 22:383 Rhodnius prolixus 26:187,230 Rhodobacter sphaeroides 28:521 Rhodoccus rhodocrous 8:299,302,303, 312 muconolactone methyl isomerase from 8:307 Rhodococcus equi 22:282 Rhodococcus erythropolis 25:150 Rhodococcus rubropertinctus 25:162, 165,166 Rhododendron arboretum 29:571 Rhododendron chrysanthum 20:17 Rhododendron cinnabarinum 29:585 Rhododendron ferrugineum 20:17 Rhododendron hirsutum 20:17 Rhododendron luteum 20:17 Rhododendron molle 13:660 rhomitoxin from 13:660 Rhododendron ponticum 20:17
Rhododendron simsii 20:17 Rhododendron sp. 25:242 Rhodophida bifida 20:356 Rhodophyllis membranacera 5:410 Rhodotorula acuata 21:391 Rhodotorula glutinis 5:292,309 Rhodotorula lactosa IFO1424 13:233 Rhodotorula minuta 5:292,299 Rhodotorula peneaus 5:292 Rhodotorula rubra 7:340;26:673 torularhodin from 7:340 Rhodotorula sp. 5:291,292 Rhoiptelea chiliantha 26:895,902 Rhopaloeides sp. 25:698 Rhus cotinus 29:579 Rhus rhodantherma 29:579 Rhus sp. 9:337;27:840 Rhus succendanea 9:319 Rhus toxicodendron 9:318,328,339 Rhus toxicodendron diversilobum 9:318 Rhus toxicodendron radicans 9:318 Rhus vernicifera 9:318,328,329,331,339 Rhyncholacis penicillata 26:471 Rhytidoponera aciculata 5:224,229,254 Rhytidoponera chalybaea 5:224,225, 229,246,254 Rhytidoponera metallica 5:224,226,229, 243-247,251,252,254,255,262,266; 15:384 Rhytidoponera sp. 5:230,247 Rhytidoponera victoriae 5:223,224, 229,251,254 Ribes nigrum 20:721 Ribes rubrum 27:839,840 extracts of 27:839 Ribes sanguineum 27:839 extracts of 27:839 Richadella dulcifica 29:605 Richardella dulcifica 27:39 miraculin from 27:39 Richardella dulcificia 27:39 Ricinus communis L. 22:531;28:400; 30:193 ricinoleic acid from 30:193 Riterella rubra 23:241 Ritterella sigillinoides 5:253;25:782, 816;28:633 eudistomin K from 28:633 Ritterella tokioka 18:881,882
1333
Rizophora apiculata Blume 30:396 Rizophora mucronata 30:396 Robinia pseudoacacia 25:93;27:374; 29:572 Rodobyrum giganteum 2:277 Rodophilia bifida 26:615 Roemeria species 2:253 Rollinia emarginlu 26:793 Rollinia mucosa 18:208 rolliniastatin from 18:208 Rollinia ~ylvatica 9:399 Rollinia ulei 27:880 Romalea microptera 9:488,489 Romneya genera 27:163 Rosa bourbonia 25:132 Rosa damascena 7:104,107,109112,125;14:425 c~-damascenone from 14:425 [3-damascenone from 14:425 y-damascenone from 14:425 c~-damascone from 14:425 [3-damascone from 14:425 7-damascone from 14:425 6-damascone from 14:425 Rosa damascena cv. trigintipentalla 7:125 Rosa davurica 23:404 Rosa rugosa 23:397,404;29:83 Rosa sp. 7:102,105,107,108,125 Rosmarinus 29:579 Rosmarinus oflqcinalis 21:599;29:587 Rosmarinus sp. 21:599;26:746;29:582 roteopsis furnensis 29:89 Roylea calycina 25:252 Rubia akone 24:304,307 Rubia cordifolia 10:640,19:776; 24:273,304,307 Rubia spp. 24:304 Rubia tinctorum 24:304;26:629-632, 638,639,641,643,644,647,648,650, 653,656,657,658,666,675- 677 anthragallol from 26:657 lucidin from 26:657 munjistin from 26:657 nordamnacanthal from 26:657 pseudopurpurin from 26:657 purpurin from 26:657 rubiadin from 26:657 xanthopurpurin from 26:657
Rubiaceae 25:180
Rubus ellipticus 22:531 Rubus foliolosits 25:251 Rubus fructicosus 20:721 Rubus ideans 20:721 Rubus sp. 21:535 Rubus suavissimus 15:16,18;27:13, 14,22-24 desglucosylstevioside from 15:14 ent-Kaurene from 27:22 labaneglycosides from 27:22 rubusodie from 27:13 rubusoside from 15:14 steviol 13-O-[3-D-glucoside from 27:13 structure of 27:24 suavioside A from 27:14,22 suavloside B from 27:14,22,23 suavloside G from 27:14,22,24 suavloside H from 27:14,22,24 suaviosdie I from 27:14,22,24 suaviosdie J from 27:14,22,24 Rudea aurea 25:93 Rumex 22:634 Ruscus aculeatus 29:587 Russula sp. 17:153 Russula subnigricans 25:765 Ruta chalespensis 7:427;22:531 for convulsions 22:531 Ruta graveolens L. 22:531 for epilepsy hysteria convulsions and fits in children 22:531 Ruta tuberculata 22:531 Rutaceae 27:164,377 Rzedowskia tolantonguensis 18:756,764; 23:682 Saccharomyces bailii 1:689;8:238 Saccharomyces carlsbergensis 19:601 ; 25:759 Saccharomyces cerevisiae 1:689,694; 2:353,390;3:302,5:418;10:526;12: 103;13:302,307,312;17:241; 18:721, 722,727;20:470;22:1,264,398,627, 628;23:110,112,115,125,126,134,474; 25:143,258,780,782;26:227,228,618, 673,1123,1125,1126,1129,1283; 28:474
1334 dimethyl allyldiphosphate isomerase from 11:201 13C-NMR spectrum of 23:114 streptovaricin C 23:64 Saccharomyces dobzhanskii 5:287 Saccharomyces drosophila 5:287 Saccharomyces fibuligera 25:308 Saccharomyces kluyveri 26:1127 Saccharomyces lactis 5:287 Saccharomyces lodderi 5:283 Saccharomyces microellipsodes 5:283 Saccharomyces phaseolosporus 5:287 Saccharomyces pretoriensis 5:283 Saccharomyces rosei 5:283 Saccharomyces sake 12:401 Saccharomyces sociasi 5:287 Saccharomyces sp. 5:279 Saccharomyces vager 5:283 Saccharomyces wieckerhamii 5:287 Saccharopolyspora erythraea 22:265 Saccharopolyspora spinosa 28:404 Saccharothrix 12:366,368 bromorebeccamycin from 12:366,368 11-dechlorobeccamycinfrom 12:366,368 rebeccamycin from 12:366,368 Saccharothrix mutabilis 19:290 Saccharothrix mutabilis subsp. chichijimaensis 10:117 Saccharothrixes 29:230 Saccharum officinale 27:191 Saccharum officinarum 15:3;29:593 Sacchromyces epidermidis 26:1095 Sacchromyces sp. 26:1087 Saccorliza polyschides 25:758 Sacupira branca 29:103 Sagittaria sagittifolia 29:617 Salacia 18:741 ;23:651 Salacia campestris 30:639,667 cyclase activity of 30:639 Salacia krausii 30:667,693,694 against bilharziasis 30:693 against dysentery 30:693 28-hydroxyisoiguesterine from 30:667 quinone methides from 30:694 Salacia macrosperma 7:150 salaspermic acid from 7:150
Salacia madagascariensis 30:667 isoiguesterine from 30:667 Salacia oblonga 30:645 uses of 30:645 Salimo salar 25:723 Saliva desoleana 26:407,409,410,411 composition of 26:407,409,410, 411 Saliva officinalis 26:391,403,404 Saliva sclarea 26:395,396,404 composition of 26:404 Salix caprea 29:581 Salix fragilis 30:195 salicin from 30:195 Salix petsusu 20:627 Salix purpurea 30:195 salicin from 30:195 Salix sachalinensis 20:613,627,628, 631,641,645 Salix sp. 21:535 Salix viminalis 29:605 Salmonella 12:63;26:1161 Salmonella abortus 28:539 in human macrophages 28:521 in peritoneal carcinomatosis 28:533 phase I trials with 28:539 receptor for 28:520 Salmonella anatum 6:262 O-antigen from 6:262 Salmonella choleraesuis 21:607 Salmonella enteridis 12:401 ;26:673 Salmonella minnesota 28:537 Salmonella monteyideo 8:102 Salmonella newington 8:101;14:233; 26:1160 O-antigenic polysaccharide from 14:233 Salmonella paratyphi 9:308;26:673 Salmonella schottmuelleri 9:308 Salmonella thompson 8:102 Salmonella typhi 9:308,12:401; 21:275,60026:673 Salmonella typhimurium TA 27:305 Salmonella typhimurium TM677 27:305 Salmonella typhimurium 5:440;9:214, 606;12:401 ;20:512;21:585,601,602; 22:616, 623,624,682;23:478;25:837;
1335 26:673,675,676,707,712,722,1002, 1093,1099-1101,1104,1105;28:519 Salmonella typhosa 12:401 Salvia 26:172;30:242 flavonoids of 30:242 Salvia acetobulosa 20:673 hormonone from 20:673 1-oxoferruginol from 20:673 3-oxoferruginol from 20:673 18-oxoferruginol from 20:673 pisiferal from 20:673 sempervirol from 20:673 Salvia aethiopis L. 29:100,690 Salvia athiopis 29:687 Salvia blepharophylla 30:246 diosmetin from 30:246 pedalitin from 30:246 Salvia candidissima 20:680,688,691 11-hydroxy- 12-methylabieta-8,11, 13-triene 11 ~-hydroxymanoyl oxide from 20:691 14-oxoisopimaric acid from 20:688 1-oxoethiopinone from 20:680 1-oxosalvipisone from 20:680 3-oxosalvipisone from 20:680 7-acetyhorminone from 20:660 7 [3-hydroxysandracopimaric acid from 20:688 8,13-di-epi-manoyl oxide from 20:691 candidissiol from 20:680 cryptanol from 20:660 crysoeriol from 20:712 diosmetin from 20:712 ferruginol from 20:660 horminone from 20:660 isopimaric acid from 20:688 manoyl oxide from 20:691 microstegiol from 20:680 montbretyl- 12-methyl ether 20:661 salvipisone from 20:680 Salvia cyanescens 30:244 salvigenin from 30:245 6-hydroxy-7,4-dimethoxyapigenin from 30:245 Salvia desoleana 26:391,406,407, 413-419
Salvia desoleana 26:416 Salvia divaricata 20:661 6-horminone-18-oic acid from 20:661 6-oxo- 12-methylroyleanone- 18-oic acid from 20:661 13-sitosterol from 20:702 oleanolic acids from 20:702 oxoroyleanone-18-oic acid from 20:661 salvinine from 20:660 ursolic acid from 20:702 Salvia dominica 27:377 Salvia forskahlei 20:672,20:710 Salvia fruticosa 27:376,377 Salvia gilliessi 21:600 Salvia glutinosa 20:707 3-acetoxy-olean-9,11-diene from 20:707 (x-amyrin acetate from 20:707 11-cholest-5-ene-313,7(x-diol- 1-one from 20:707 erithrodiol 28-acetate from 20:707 3 [3-hydroxy- 11-oxo-oleana- 12-ene from 20:707 3 [3-hydroxy- 11-oxo-ursa- 12-ene from 20:707 7c~-hydroxysitosterol from 20:707 lupeol from 20:707 1-oxo-7cz-hydroxysitosterol from 20:707 oxo-(x-amyrin from 20:707 11-oxo-[3-amyrin from 20:707 oleanolic acid from 20:707 stigmasterol from 20:707 sitosterol from 20:707 ursolic acid from 20:707 Salvia heldreichiana 20:690,711 7-oxo- 13-epi-pimara-8,15-diene18-oic acid from 20:690 7[3-hydroxy sandracopimaric acid from 20:690 di (4,4'-hexyloxy-carbonylphenyl) ether from 20:709 heldrichinic acid from 20:670 isopimaric acid from 20:690 salvigenin from 20:711
1336 Salvia hierosolymitana 20:672 forskalinone from 20:672 Salvia leucophylla 20:4 Salvia limabata 20:673,683,702,712 abieta-8,11,13-triene from 20:673 cz-amyrin from 20:702 dehydrosalvilimbinol from 20:683 eupatilin from 20:712 ferruginol from 20:673 12-hydroxysapriparaquinone from 20:683 3,12-hydroxysapriparaquinone from 20:683 2-hydroxysaprorthoquinone from 20:683 limbinol from 20:683 luteolin from 20:712 manool from 20:691 pectolinarigenin from 20:712 quercetin-3-methyl ether from 20:712 salvilimbinol from 20:683 stigmasterol from 20:702 vergatic acid from 20:702 Salvia miltiorrhiza 2:402,26:235,29:212 cell suspension cultures of 2:402 danshensuan B from 26:235 Salvia montbretii 20:666,678,712,704 cz-amyrin from 20:704 apigenin from 20:712 7,7'-bistaxodione from 20:678 cirsitiol from 20:712 3 f3-O-trans-p- coumr o ylmono gyno 1 A from 20:704 3 f3-O-trans-cis-coumaroylmonogynol A from 20:704 11,11 '-didehydroxy-7,7'dihydroxytaxodione from 20:678 demethyleryptoj aponol from 20:666 ferruginol from 20:666 ferruginyl 12-methyl ether from 20:666 hypargenin F from 20:666 6-hydroxy-salvinolone from 20:666 7-hydroxy-axodione from 20:666 14-hydroxyferruginol from 20:666
luteolin from 20:712 lupeol from 20:704 monogynol A from 20:704 oleanolic acid from 20:704 salvinolone from 20:666 salvinolonyl- 12-methyl ether from 20:666 [3-sitosterol from 20:704 taxodione from 20:666 ursolic acid from 20:704 Salvia multicaulis 20:676,690 7[3-hydroxy-3,11-dioxo-pimara8(14), 15-diene from 20:690 horminone from 20:673 12-methyl-5-dehydrohorminone 20:676 12-methyl-5-dehydroacetythorminone 20:676 1-oxoferruginol from 20:673 3-oxoferruginol from 20:673 18-oxoferruginol from 20:673 pisiferal from 20:673 sempervirol from 20:673 salvipimarone from 20:690 Salvia napifolia 20:670 acetyl-horminone from 20:670 cryptanol from 20:670 cryptojaponol from 20:670 11,12-dioxoabieta-8,13-diene from 20:670 7,20-epoxyroyleanone from 20:670 ferruginol from 20:670 horminone from 20:670 1-oxoferruginol from 20:670 6-oxoferruginol from 20:670 pachystazone from 20:670 sugiol from 20:670 6,12,14-trihydroxyabieta6,8,11,13-tetraene from 20:670 Salvia nemorosa 20:669,702,712;22:531 apigenin from 20:712 ot-amyrin from 20:702 2et, 14-dihydroxydehydroabietic acid from 20:669 eupatilin from 20:712 luteolin from 20:712 24-methylenecycloartenol from
1337 20:702 nemorosine from 20:669 oleanolic acid from 20:702 salvipisone from 20:683 salvinemoral from 20:702 [3-sitosterol from 20:702 stigmast-7-en-3-one from 20:702 stigmast-4-ene-3-one from 20:702 stigmast-7-en-3-ol from 20:702 ursolic acid from 20:702 Salvia officinal& L. 7:119;11:220;25:128; 26:402;27:376,377;28:391 ;30:219 essential oils from 28:391 neolignan from 30:219 Salvia pinnata 30:244 apigenin from 30:244 luteolin from 30:244 Salvia plebeia 30:247 hispidulin 7-glucuronide from 30:247 Salvia pomifera 20:663,702,705 c~-amyrin from 20:702 erithrodiol from 20:705 ferruginyl 12-methyl ether from 20:663 23-hydroxygermanicone from 20:705
18-Hydroxyabieta-8,11,13-triene-
7-one from 20:663 lupeol from 20:702 moradiol from 20:705 moronic acid from 20:705 pomiferin A-G from 20:663 13-sitosterol from 20:702 taraxasterol from 20:702 Salvia potentillifolia 20:660 Salvia prionitis 5:31,33,36 Salvia sclarea 7:101,103,110,123;20:660, 669,633,691,712;22:531 ;25:246,253 ;2 6:391-395,397,398,400-406,412, 413,415-419;27:376,377 sclareol from 7:121 Salvia serotina 28:400 Salvia sp. 21:599 biological investigations of 20:659 chemical investigations of 20:659 Salvia splendens 5:646
Salvia tchihatcheffii 20:676,707 3-acetylerythrodiol from 20:707 28-acetylerythrodiol from 20:707 3-acetyloleanolicaldehyde from 20:707 3[3-acetylolean- 12-en-28-al from 20:707 salvitchitatine from 20:676 tchitatine from 20:676 Salvia tomentosa 20:9,667 ferruginol from 20:667 horminone from 20:667 1-oxo-abieta-8,11,13-triene- 18-oic acid from 20:9 Salvia triloba 20:711;29:588;30:243 salvigenin from 20:711 ;30:243 Salvia uliginosa 30:247 petals of 30:247 Salvia wiedemanni 20:688,711 7 ~-hydroxysandracopimaric acid from 20:688 isopimaric acid from 20:688 14-oxoisopimaric acid from 20:688 salvigenin from 20:711 Salvia yosgadensis 20:692,712 ambrenolide from 20:692 apigenin-7-methyl ether from 20:712 apigenin-4-methyl ether from 20:712 apigenin-7,4-dimethyl ether from 20:712 apigenin-6,4-dimethyl ether from 20:712 apigenin from 20:712 6c~,14-dihydroxymanoyl oxide- 15, 17-diene- 16,19-olide from 20:697 6a, 16-dihydroxymanoyl oxide14,17-diene- 16,19-olids from 20:697 6a-hydroxyambrenolide from 20:692 6a-hydroxynorambrenolide from 20:692 6a -hydroxy-8a-acetoxy- 13,14,15, 16-tetranorlabdane- 12-oic acid
1338
20:692 kaempferol-3-methyl ether from 20:712 luteolin from 20:712 norlabdane diterpenoids from 20:692 norambrenolide from 20:692 yosgadensonol from 20:696 13-epi-yosgadensonol from 20:696 yosgandensolide A and B from 20:696 Sambucus nigra 28:424;29:609;30:407 antiviral activity of 30:407 Sanguinaria canadensis L. 27:155,158, 159,162,169 structure of 27:169 Sanguisorba officinalis 17:421,423; 23:397 polyphenols 17:423 Sanicula 29:581,582 Saniculoideae 27:661 Santalum album 8:145 ~-santalol from 8:145 Santonia chamaecyparissus 7:100,101; 29:88 Sapindus emarginatus L. 22:531 for epileptic fits 22:531 Sapindus mukurossi Gaertn 27:21 22:531 for epilepsy 22:531 Sapindus rarak DC 21:660;27:13 mukurozioside from 27:13 Sapindus trifoliatus L. 22:531 for epilepsy, hysteria and hysteroepilepsy 22:531 Sapium 25:242 Sapium genera 27:830 Sapium indicum 7:188 4a-sapinine from 7:187 Saponaria 26:55 Saponaria officinalis 24:131,144,149, 155,161 ;26:3,4,10,13,15,17,18,20 27,3 0,42,54,57 ;30:407 antiinflammatory activity of 26:27 antiviral activity of 30:407 gypsogenic acid from 26:5,6,18 gyspogenin from 26:5,6,18
313-hydroxy-oleana-11,13( 18)-dien23,28-dioic acid from 26:5,6 saponarioside from saponariosides C-M from 26:10,12,13,17,18 saponaside A from 26:17,20-23,42 3,4-secogypsogenic acid from 26:5,6 triterpenoid saponins from 26:17,20 Saposhnikovia divaricata 27:422;29:682 Saposhnikoviae radix 27:422 Saprolegnia parasitica 9:577,578 Saprophyton glaucum 9:37 papkusterol (glaucasterol) from 9:37 Sarcina lutea 12:401;23:199 Sarcocapnos enneaphylla 3:428
Sarcodon leucopus (Sarcodon laevigatus) 29:278
Sarcomelicepe agyrophylla 20:807 Sarcomelicepe simplieifolia 20:807 Sarcomelicope dogniensis 20:806 Sarcomelicope glauce 20:806 Sarcophyton glaucum 8:18;21:279 Sarcophytum sp. 25:704 Sarcoptes mites 28:410,416 cause of human scabies 28:410 symptoms of 28:410 Sarcoptes scabiei 28:409,416 cause of mange mites 28:409 cause of scabies 28:409 Sargasm horneri 30:400,405 anti-CMV activity of 30:405 polysaccharide (PS) from 30:400 Sargassum lacerifolium 25:867 Sargassum muticum 26:1152 Sargassum tortile 20:25-27,29,34-36 Sargasum muticum 30:400 polysaccharide (PS) from 30:400 Sarotherodon nilotica 7:184 Sarothra gentianoides 30:605 n-nonane from 30:605 Sassafras sp. 21:596 Saururus cernuus 17:319 Saussurea lactone 7:216,237 Saussurea lappa 22:531,29:89,90 for epilepsy 22:531 Saxicola insignis 5:837 hemoglobin components of 5:837
1339 Saxidomus gigantius 5:3 Scaevola racemigera 6:522 strychnovoline from 6:522 Scenedesmus obliquus 26:373 Schaefferia cuneifolia 18:761 Schefflera sp. 27:686 Schelhammera spp. 3:455,483 Schelhammmera pedunculata 3:484,486 Schima walichii 23:405 Schinus terebinthifolius 22:131 Schisandra 26:183 effect on cardiovascular system 26:183 decrease by heart rate 26:183 display platelet activating factor antagonist activity 26:183 for the treatment of hepatitis 26:183 Schisandra chinensis 26:203,204,244, 247,249-251,255,258,265 chamigrenal from 26:244 gomisin N from 26:249 pregomisin from 26:244 schisandrin A from 26:203,244 schisandrol A&B 26:203 schisandrin C 26:203 Schisandra rubriflora 26:205 Schistocera gregaria Schistocerca 9:498 Schistocerca gregaria 24:715,716; 26:700;29:6 Schistochila appendiculata 2:280281 Schistosoma haematobium 7:425 Schistosomajaponicum 7:425;23:138 Schistosoma mansoni 7:425,428;23:138 Schizandra sp. Schizaphis graminum 23:535 Schizolobium parahybum 29:605 Schizonepeta tenuifolia 26:251,252 schizotenuin A from 26:251,252 schizotenuin C~ from 26:251,252 schizotenuin C2 from 26:251,252 Schizophyllum commune 1:680,681; 5:288,316;18:460,813,814;8:352; 23:111,115;25:452 cellulase from 8:352 fruiting body formation of 1:680,681
Schizosaccharomyces octosoporus 5:280,286,293 Schizosaccharomyces pombe 5:280,286; 12:398;18:721 ;26:1093,1097,1098, 1128 Schizothrix calcicola 18:294,20:586 Schlerochiton ilicifolius A 15:335; 27:18,38 monatin from 27:18 Schlerochiton ilicifolius A. 27:18 Schumanniophyton magnificum 21:139, 140 Schumanniophyton sp. 21:124,125, 144,153 Schwanniomyces alluvius 5:283 Schwanniomyces castelli 5:283 Schweinfurthia papilionaceae 9:75,76,78 alkaloids from 9:75,76,78 Sciadopitys verticillata 20:107; 23:489,493 Scilla maritima 25:535 Scleritoderma sp. 26:1215 Sclerotinia 4:246 Sclerotinia cinera 12:401 Sclerotinia fructicola 6:546,547 sclerosporin from 6:546 Sclerotinia sclerotiorum 15:385;18:269; 21:197,209;23:125;26:405,418; 28:123 Sclerotium cerevisiae 5:279-282,285,323 Sclerotium fermenti 5:280 Sclerotium fragilis 5:280,282 Sclerotium glucani 5:277 Sclerotium glucanicum 5:314;23:115,142; 30:401 scleroglucan from 30:401 Sclerotium libertiana 5:277 Sclerotium rolfsii 5:314;21:234,235; 23:142;26:405,418 Sclerotium rouxii 5:282 Scolytus multistriatis (elm-bark beetle) 15:348;19:127 multistriatin from 14:274 (3S,4S)-4-methyl-3-heptanol from 11:412 Scolytus scolytus 15:348,349 Scopaliajaponica 22:531 Scoparia dulcis 21:689,690,692,704, 722,723 ;25:263 ;27:193 ;29:101
1340
Scopolia genus 17:395 Scopoliajaponica Maxim. 5:505;22:742; 22:532 atropine from 5:505;22:742 for convulsions 22:532 Scopolia sp. 21:104 Scorpiurus muricatus 19:117 Scripus maritimus 9:391 Scrophularia auriculate 29:84 Scrophularia canina 7:476 Scrophularia scorodonia L 29:685 Scutellaria altissima 30:250 baicalein from 30:250 Scutellaria baicalensis 24:219-228,220, 223 ;27:431 ;29:678;30:55,56,69,254, 289 baicalein from 30:55 flavonoids from 30:56,289 in allergric inflammatory disease 30:69 viscidulin III from 30:254 Scutellaria discolor 30:251 norwogonin from 30:251 wogonin from 30:251 Scutellaria galericulata L. 22:532 for epilepsy 22:532 Scutellaria lateriflora L. 29:678 Scutellaria ocellata 30:248 wogonin from 30:248 Scutellaria orthocalyx 29:679 Scutellaria przewalskii 30:249 apigenin from 30:249 Scutellaria spp. 29:581 Scutellaria tenax 5:678 Scutellariae radix 27:431 Scylonema hofmanni 26:363 Scyphyphora hydrophyllaceae 7:176 Scytonema mirabile 28:144 Scytonema sp. 5:429 Secale cereale 18:500,502,512;19:247; 27:125,188,191,193,216,217;29:613 Securidoca longepedunculata 22:532 Securiflustra securifrons 18:691 Securinega alkaloids 5:49 Securinega sp. 10:153 Securinine alkaloids 14:657-659 synthesis of 14:657-659 via Norrish type II reaction 14:657-659
Sedum sarmentosum 21:737 Selaginella tamariscina 24:273 Selenastrum capricornutum 26:373,374, 377-379,29:329 Selinum vaginatium 5:728 Selligueafeei Bory 15:33;27:18,35 selligueain A from 27:18,35 Semecarpus anacardium L. 22:532 for epilepsy and hysteroepilepsy 22:532 Semecarpus heterophylla 9:319 Semecarpus vernicifera 9:319 Senecia isatideus 21:305,306 Senecio 26:872 Senecio amplexicaulus 14:450 endesm- 11-en- 14-ols from 14:450 (+)-intermedeol from 14:450 Senecio erraticus 26:874 Senecio glaber 26:874 Senecio litura 26:851,853-855,858860,863-866 Senecio microphyllus 26:874 Senecio oxyodontus 13:13 senoxydene from 13:13 Senecio palmensis 26:859 Senecio toxicosis 7:23 Senna multiglandulosa 22:580 Senna occidentalis 26:1143 Senna spp. 22:580;26:1139 Sentellaria scandens 30:253 5,7,2',5'-tetrahydroxy-6methoxyflavanone from 30:253 Sepedonium ampullosporum 25:318 Septoria lycopersici 25:293,295,301,302, 304,307,308,314-316 Sequoia sempervirens 28:408 Seratia marcescens 12:103 Sericea lespedeza 21:502,521 Serindea warneckei 23:342 Serjania salzmanniana 21:660 Serratia marcescens 9:308;12:401; 22:627;26:402 Serratia sp. 4:434;12:103 Sesamum angolense 7:407,417,423 23:342,343 Sesamum indicum 26:249 pinoresinol from 26:249 sesaminol from 26:249 sesamol from 26:249
1341
Sesbania drummondii 1:305,514 Sesbania punicea 1:305 Sesbania sesban 7:427,432,433; 21:506,542 Sesbania vesicaria 1:305 Setaria cervi 21:674 Setaria FMTI 29:600 Setaria italica 25:781 ;26:476 Shaefferia cuneifolia 23:659 Shewanella putrefaciens 26:69 Shigella flexnert 14:233 O-antigenic polysaccharide from 14:233 Shigella ambigua 26:673 Shigella boidii 26:673 Shigella boytic 25:260 Shigella dysenteriae 9:308 Shigella flexneri 26:673,1160;29:526 Shigella largei-sachsii 26:673 Shigella lycopersici 25:306,313 Shigella shiga 25:260 Shigella sonnei 9:308;12:401 ;26:673 Shigella sp. 12:63 Shizandra chinensis B 18:589;25:476 Shodoptera littorolides 20:245 Shorea disticha 23:547 Shuteria vestita 22:459 Sida acuta 5:751 Sida carpinifolia 5:752 Sida cordifolia L. 5:75;22:532 for fever 22:532 Sida rhombifolia 5:751 Sida sp. 5:751 Sideritis angustifolia 29:687 Sideritis arborescens 25:249,250 Sideritis foetens 25:250,254;29:102 Sideritis gomerae 25:249 Sideritis javalambrensis 25:250,263,274; 29:102 Sideritis leucantha 22:429 Sideritis lycopersici 25:308,314 Sideritis marmorea 30:260 trimethoxykaempferol 30:260 Sideritis mugronensis 25:250;29:102,701 Sideritis nutans 25:249 Sideritis raeseri 30:258 apigenin from 30:258 Sideritis shiga 25:260
Sideritis sp. 5:658;30:259 p-coumaroylglucosides from 30:259 Sideritis varoi 25:250 Sidnyum turbinatum 28:643 1-heptadecanyl sulfate from 28:643 1-hexyl sulfate from 28:643 1-octadecanyl sulfate from 28:643 sodium (2S)-2,6,10,14-tetramethylpentadeca- 1,18-diyl sulfate from 28:643 Sidonops microspinosa 28:681 Silene fortunei 26:46,47,55 Silenejenisseensis 24:150,151, 26:45,46,47 Silene latifolia 26:45 Silene rubicunda 26:45 Silene sp. 26:45 Silene succulenta 26:45 Silene villossa 26:45 Silene vulgaris 26:47,48 Siler trilobum 29:83 Siliquariaspongiajaponica 25:723,759 Silphinium perfoliatum 8:165;13:8,11 silphinene from 8:165;13:8 (-)-silphiperfol-6-ene from 13:8,11 Silybum marianum 5:496;26:255 silymarin from 13:660 Simaba amara 7:369,381 Simaba cedron 7:392 Simaba cuspidata 7:369,381 Simaba guianensis 26:815 Simaba multiflora 7:369,380,396 Simarouba 26:837 Simarouba glauca 13:660 glaucarubin from 13:660 Simerestis welwitschii 23:660 Sinapis alba L. 25:781;26:612,1074 Sinapis arvensis 29:618 Singmadocia symbioltica 25:902 Sinomenium acutum 25:476 Sinularia spp. 29:91 Sinularia dissecta 23:170;25:704 Sinularia flexibilis 25:690 Sinularia nanolobata 25:690 Sinularia sp. 21:276 Siphocampylus verticillatus 30:204 antinociception effect of 30:204
1342
piperidine alkaloid hydrochloride from 30:204 Siphonaria atra 17:25 Siphonaria baconi 17:25,28 Siphonaria diemenesis 17:24 Siphonaria laciniosa 17:25 Siphonaria maura 17:25,26 Siphonaria normalis 17:25,27 Siphonaria sp. 17:23,26,28 Siphonaria zelandica 17:25 Siphonoborgia sp. 9:37 (22R,23R)-22,23-methylene cholesterol from 9:317 Siphonodictyon coralliphagum 28:669 bis(sulfato)cyclosiphonodictyol A 28:669 siphonodictyal D from 28:669 siphonodictyols G from 28:669 Siraitia grosvenorii 15:5,22;27:6,7,14,15 mogroside IV from 27:14 mogroside V 27:6,7,14 siamenoside I from 27:15 Siraitia siamensis 15:24;27:14,15 siamenoside I from 27:15 Sirychnos nux vomica L. 22:533 Sitobion avenae 27:213 Sitophilus granarius 18:698;24:101 Sitophilus oryzae 9:299; 21:595,618; 24:716 Sium latifolium 5:724,728,20:6 Sium latijugum 5:728 Smenospongia aurea 5:437 8-epichromazonaral from 15:291 Smenospongia sp. 5:429,43-0,432-434, 439 Smilax glycyphylla Sm. 27:17 glycyphyllin from 27:17 Smirnovia turkestana Bunge 27:517 Snechocystis sp. 25:718 Sodoptera littorais 18:772 Solamum melongena 23:757 Solanaceous sp. 25:304,368 Solanum acaule 23:343 Solanum alkaloids 7:17,19,21,22,24 Solanum americanum 22:532;29:611 Solanum carolinense L. 22:532 for epilepsy and convulsions 22:532
Solanum dasyphyllum 22:532 as anticonvulsant agent 22:532 Solanum dimidiatum 22:739 Solanum dulcamara 20:135;29:591 Solanum eleagnifolium 7:19 Solanum incanum L. 22:532;28:400 for epilepsy 22:532 Solanum indicum L. 20:135;22:532 Solanum kwebense 22:739 Solanum mammosum 7:427 Solanum melongena L. 20:135;21:239; 22:532,721;29:591,611 Solanum nigrescens 21:662 Solanum nigrum 22:532 as anticonvulsant agent 22:532 Solanum ridellii 7:23 Solanum sodomaeum L. 22:532 as antiepileptic agent 22:532 Solanum sp. 7:21,22;25:293 Solanum torvum 22:532 Solanum tuberosum 7:20,22;20:135; 22:721 ;26:936,941 ;29:582,584,600 Solanum umbelliferum 20:489 steroidal alkaloids from 20:489 Solanum xanthocarpum 20:135;22:532 for epilepsy 22:532 Solaria cervi 26:467 Solaster borealis 15:55 solasteroside from 15:55 Solenopis aurea 6:423 piperidine venom alkaloids in 6:423 Solenopsis (fire ants) 6:422 Solenopsis A 1:389,390 Solenopsis carolinensis 6:423 piperidine venom alkaloids in 6:423 Solenopsis conjurata 6:450 indolizidine alkaloids in 6:450 piperidine venom akkaloids in 6:423 Solenopsis eduardi 6:423 piperidine venom alkaloids in 6:423 Solenopsis fugax 6:436 piperidine venom alkaloids in 6:436
1343
Solenopsis geminata 6:423 piperidine venom alkaloids in 6:423 Solenopsis invicta 1:682 pheromone synthesis 1:682 Solenopsis invicta 3:273;5:228 piperidine venom alkaloids in 6:423 Solenopsis littoralis 6:423 piperidine venom alkaloids in 6:423 Solenopsis molesta 6:436 pyrrolidine venom alkaloids in 6:436 Solenopsis pergandei 6:423 piperidine venom alkaloids in 6:423 Solenopsis punctaticeps 6:423 pyrrolidine venom alkaloids in 6:423 Solenopsis richteri 6:423 piperidine venom alkaloids in 6:423 Solenopsis saevissima 6:423 piperidine venom alkaloids in 6:423 Solenopsis sp. 6:450,454;11:231;27:246 alkyl- 1-piperideine in 6:422 arthropod alkaloids from 11:231 Solenopsis texanas 6:436 pyrrolidine venom alkaloids in 6:436 Solenopsis xyloni 6:422,423 2-methyl-6-alkyl- 1-piperideine in 6:422 piperidine venom alkaloids in 6:422,423 Solidago altissima 19:247 Solidago saponins 15:191 Solidago sp. 6:28 kolavenic acid from 6:28 Solidago virgaurea 21:634,660,662 Solmonella anatum 8:101,103 Solunum xanthocarpum 22:532 Sonneratia alba 7:176,194,195 Sonneratia apetala 7:188 Sonneratia caseolaris 7:176 Sonneratia grifiithie 7:195 Sonneratia ovata 7:176
Sonneratia sp. 7:176 Sophora chrysophylla 15:522 Sophora flavescens 9:148;25:93;26:487; 29:705
Sophora griffithii 9:149 Sophorajaponica 26:1142;29:573 Sophora significantly 22:431 Sophora sp. 30:205 sophoranol from 30:205
Sophora subprostrata 22:425;25:93; 29:774
Sophora tomentosa 15:522 (-)-epilamprolobine from 15:522 (+)-epilamprolobine N-oxide from 15:522 5-(3 '-methoxyc arb onylbutyroyl)
aminomethyl-trans-quinolizidine
N-oxide from 15:522 Sophora tonkinensis 27:275 Sorangium cellulosum 25:779 Sorbus aucuparia 23:342 Sordaria fimicola 21:209,227,228,241 Sorgassum tortile 25:839 Sorghum bicolor 9:322,344;21:505; 29:593 Sorghum biolor 29:601 Sorocea bonplandii 17:458 Soulamea soulameoides 7:396 Soulamea tomentosa 7:369,381 Souliea 25:180 Soymida febrifuga 29:585 Spergularia ramosa 26:49 Sphaerantnus indicus 9:145 Sphaerechinus granularis 15:104 Sphaereophorus globosus 5:310 Sphaerodiscus placenta 7:304-306 22-dehydrohalitylosides D,E from 7:298 halitylosides A,B,E from 7:298 placentoside A from 7:298 Sphaerophorin cetraria 9:317 Sphaerotheca pannosa 27:178 Sphaerotrichia 26:1121 Spheciospongia vagabunda 9:37 (24S,25S)-24-26-cyclocholesterol from 9:37 Spigelia anthelmia 26:852;28:400 Spilantes leiocarpa 24:103 Spilanthes alba 10:152;21:378;24:690
1344
Spilanthes mauritiana 21:378;22:532 Spilanthes oleracae 24:689 Spinacia oleracea L. 22:482;29:586 Spinus tristis 5:836 hemoglobin components of 5:836 Spiphonodicyton coralliphagem 25:694 Spirastrella abata 25:722 Spirastrella sp. 25:719 Spirastrella spinispirulifera 25:759 Spirulina platensis 25:725;30:399,404, 408 anti-influenza activity of 30:408 biological activity of 30:404 calcium spirulan from 30:b399 polysaccharide (PS) from 30:408 Spizella arborea 5:837 hemoglobin components of 5:837 Spizella passerina 5:837 hemoglobin components of 5:837 Spodoptera frugiperda (army worm) 14:451 Spodoptera eridania 7:396;26:871 Spodoptera exigea 25:792 Spodoptera frugiperda 23:666 Spodoptera littoralis 18:772,20:245 21:252,257,262,264,266,267,273,275; 23:291,669,842; 26:850,852-854, 869,870-872,874-876 Spodoptera litura 24:715,716;26:850 Spongia hispida 15:312 Spongia mycofijiensis 19:568;25:896; 28:710 Spongia nitens 17:10 Spongia officinalis 6:56,107,108;17:10; 25:688 isoagatholactone 6:56,107,108 Spongia sp. 25:759;5:371;6:107,111 Spongosorites sp. 25:707,799 Sporangium cellulosum 26:450 Sporobolomyces odorus 13:309,312; 21:197 Sporobolomyces reseus 5:291 Sporobolomyces sp. 5:291;13:315 Sporomia fungi 15:384 6-methoxymellein from 15:384 sporomiella australis 22:70 Sporomiella intermedia 22:70,253;23:344 Sporothrix curviconia 5:304 Sporothrix flocculosa 21:189;22:74
Sporothrix inflata 5:304 Sporothrix rugulosa 22:74 Sporothrix schenckii 5:302-305,322,325 monohexosylceramides 18:807
Sporothrix schenckii var. luriei 5:304 Sporothrix sp. 5:302,304,325,328 Sporotrichum dimorphosporum 8:349 xylanase A 8:349 xylanase B 8:349
Sporotrichum pulverulentum 26:1013 Sporotrichum thermophile 2:323 Sprekelia formosissima 20:356 Stachybotrys sp. 21:233 Stachys chrysantha 30:270 xanthomicrol from 30:270
Stachys flavonoids 30:270-272 Stachytarpheta cayennenis 25:611,613; 28:400;29:84
Stagonospora genus 28:149 Staphyllococcus aureus 23:164,238; 30:693 minimal inhibitory concentration (MIC) of 30:693 Staphyllococcus epidermidis 30:693 minimal inhibitory concentration (MIC) of 30:693 Staphyllococcus saprophyticus 30:693 minimal inhibitory concentration (MIC) of 30:693 Staphyllococcus warnieri 30:693 minimal inhibitory concentration (MIC) of 30:693 Staphylococcus albus 22:398 Staphylococcus aureofaciens 28:135 as antibacterial agent 28:135 Staphylococcus aureus 3:302;5:368,370; 505,511 ;7:282,304,309;9:308,500; 8:102;10:117;12:401 ;13:162,164,173, 181,183;17:285;18:777,778;19:556, 601,712;20:30,32;21:262,266,599, 600,601,602,604,615 ;22:627,628,675; 23:41,136,158,474,535 ;25:253,257, 259,260,271,765,770,776-778,789, 791,821 ;26:77,79,83,227,330-333, 402,673 ;29:269,324,339;30:628,739 antibacterial activity against 30:739 antibacterial properties of 30:628 antifungal activity against 30:739 Staphylococcus botryosum 25:305
1345
Staphylococcus citerus 9:308 Staphylococcus coli 23:533 Staphylococcus epidermidis 9:308; 12:401 ;13:164,173 ;20:712;25:776; 26:402,1093,1095,1097,1098 amylopectin in 7:32 amylose in 7:32 enzymatic conversion to glucose 2:321 enzymatic hydrolysis of 10:496-503 Staphylococcus ganera 29:311 Staphylococcus haemolyticus 25:776 Staphylococcus hominis 25:258 Staphylococcus spp. 26:556 Staurogyne merguensis Wall. 27:39,40 strogin 1 from 27:39,40 strogin 2 from 27:39,40 strogin 4 from 27:39,40 Staurosporeus 27:862,863 Steganotaenia araliacea 17:346;26:216; 29:360 episteganangin from 26:216 steganangin from 26:216 stegancin from 26:216 steganolide A from 26:216 steganoate B from 26:216 Stellaria media 24:273;25:781 Stellera chamaejasme 27:831 Stelleta globostellata 21:254,273 Stelleta sp. 21:269,273 Stelleta sponge sp.25:700 Stelospongia conulata 15:312 Stemonajaponica 21:759 Stemona mairei 21:759,764 Stemona parviflora 21:759,764 Stemona sessilifolia 21:759,764 Stemona tuberosa 21:752,760,764,769 Stemonoporous canaliculatus 23:547 Stemphylium botryosum 25:307 Stemphylium epidermidis 25:258,259 Stemphylium radicinum 19:154 Stemphylium solani 25:302,303,307 Stemphylium sonnei 25:260,305 Stenodynerus floridans 5:223,253 Stenodynerus fulvipes 5:223,224,232,253 Stenogramme interrupta 30:402 carrageenans from 30:402 Stenotrophomonas maltophilia 28:140
Stentor coerulus 22:647 Stephania cepharantha 22:533 for epilepsy 22:533
Stephania erecta 20:522;29:578 Stephaniajaponica 6:480 protostephanine in 6:480
Stephania pierrei 20:522 Stephania tetrandra 22:69;24:895; 25:476;29:578
Stephania venosa 2:253 Stephanitis 26:443 Stephanotis lutchuensis Koidz. var. japonica 21:674,27:41 sitakisoside I-IV, XI-XIII from 27:41 sitakisoside XVI from 27:41 sitakisoside XVIII from 27:41 Steptocarpus dunnii 29:733 Steracaulon ramulosum 5:310,311 Sterculia lychophora 24:275 Sterculia urens Roxb. 405 antiviral activity of 30:405 Stereocaulonjaponicum 5:310 Stereum purpureum 26:133 Sterllaria dichotoma 26:41 Stevia 27:299-317 acute toxicity tests of 27:307 allergenic activity of 27:315 as sweetner 27:299-317 chronic toxicity studies of 27:306-308 consequences for bioavailability of nutrients 27:312-314 effect on fertility 27:309,310 for diabetics 27:314 for stevioside 27:307,310 immunological activity of 27:315 nutritional significance of 27:314,315 safety evaluation of 27:299-317 subacute toxicity studies of 27:307,308 Stevia phlebophylla 15:16 Stevia purpurea 8:44-46 1-bisasolones from 8:44-46 Stevia rebaudiana 15:4,5;27:8,9,13,22, 299,311 ;29:101 ent-kaurene from 27:22 labdane glycosides from 27:22
1346 of asteraceae 27:299 rebaudioside A from 27:8,9,13 rebaudioside B from 27:13 rebaudioside C from 27:13 rebaudioside D from 27:13 rebaudioside E from 27:13 stevia extract from 27:8 steviolbioside from 27:13 stevioside from 27:8 sugar-transferred Stevia extract 27:8 Stevia selriana 25:251 Stichococcus bacillaris 26:358 Stichopus chloronotus 7:272;15:87; 28:593 stichlorosides A1, BI, C~ and A2, B2, C2 15:87 Stichopus japonicus 7:277 holotoxins A, A~, B and B~, 15:87 Stichopus sp. 7:282 Stichopus variegatus 7:272,282 stichoposide D from 7:273 Stilbella sp. 21:224 Stillingia lineata 7:417 Stiretrus anchorago 26:66 Stoichactis helianthus 26:11 Stomoxys calcitrans 26:691 Stomphia coccinea 15:66;28:717 benzyltetrahydroisoquinoline imbricatine from 28:717 Stongylocentrotus purpuratus 9:575 Streblus asper 26:467 Strenbergia lutea 26:609-612,614,615 Streotpmyces lysosuperficus 1:417 Strepromyces albolongus 23:61 Streptococci 29:535 classification of 29:535 identification of 29:535 pathogenicity of 29:535 serological groups of 29:535 Streptococcus bovis 19:696 Streptococcus durans 25:259 Streptococcus faecalis 4:432,12:103,401;
12:401,19:696;25:259,260;26:77,83;
Streptococcus fecalis var. liquifaciens 25:923
Streptococcus fecium 25:925 Streptococcus ganera 29:311 Streptococcus haemolyticus 26:673
Streptococcus mutans 7:69;18:673, 20:32,34,36;23:536;26:64,226,227; 27:778 Streptococcus pneumoniae 14:233; 25:780;26:1154 capsular polysaccharide 14:233 Streptococcus pyogenes 5:601,9:308, 10:117,13:162,173,181,183,19:492;25 :452,776
Streptococcus pyogenes haemolyticus 29:324
Streptococcus salivarius 26:402 Streptococcus sanguis 7:69;26:402 dextransucrase from 7:41
Streptococcus sobrinus 27:316,778 Streptococcus sp. 5:325;16:108;21:615;25:257;26:114 5;29:230 Streptomyccs griseus SS-20 24:937 Streptomyces sandaenis 13:434 Streptomyces spiroverticillatus 27:879 Streptomyces achromogenes 23:68,88 Streptomyces actuosus 12:365;21:399 staurosporin ("NB-2025") from 12:365 alisamycin from 21:399 Streptomyces aizunensis 12:63 aizumycin from 12:63 Streptomyces albus 21:420 porothramycin A from 21:420 Streptomyces aldus 25:781 Streptomyces althioticus 28:143 Streptomyces amakusaensis 19:178 Streptomyces ambofaciens 5:613,614 Streptomyces antibioticus 11:214,215 chlorothricin producer 11:214,215 Streptomyces antibioticus 21:303; 26:1010;29:319 boromycin from 21:303 Streptomyces arenae 29:319 Streptomyces aureofaciens 21:414;29:312 Streptomyces aureus 5:429,434 Streptomyces avermitilis 1:435;28:396 avermectins from 12:3
Streptomyces azureus thiostrepton from 11:209
Streptomyces bikiniensis 18:700 Streptomyces cacaoi 23:343 Streptomyces cacaoi var. asoensis 1:399
1347
Streptomyces caespitosus 9:431 ;13:434 albomitomycin A from 13:433 isomitomycin A from 13:433 mitomycins A-C from 13:433 Streptomyces cattleya 11:210;12:145 thienamycin from 11:210;12:145 Streptomyces cattleya 29:343 Streptomyces cellulosae 12:103,54; 21:197 Streptomyces chrysomallus 8:102; 26:1010 Streptomyces cinnamonensis 11:197 Streptomyces clavuligerus 22:263
Streptomyces coelicolor Streptomyces coelicolor 5:617,618; 22:263,265
Streptomyces collinus 11:189-191; 23:65,66;29:322 ansatrienin (mycotrienin) from 11:189 enoyl CoA reductase from 11:190-191 Streptomyces curacoi 29:325
Streptomyces diastatochromogenes
12:366 staurosporine from 12:366 Streptomyces distallicus 5:551 Streptomyces erythreus 13:166;25:780 Streptomyces exfoliatus 23:343 Streptomyces flaveolus 14:97,98;21:412; 28:131 tirandamycin A from 14:98 tirandamycin B from 14:97,98; 21:412 Streptomyces flavogriseus 10:103 Streptomyces fradiae 5:591 ;29:329 urdamycin from 11:134 Streptomyces fungicidus 29:332 Streptomyces genus 29:321 Streptomyces globisporus 29:326 Streptomyces gougerotti 4:242 Streptomyces graminofaciens 29:326
Streptomyces griseochromogenes 4:242;18:269;28:127
Streptomyces griseoflavus 12:63;19:165, 167;19:165,177;21:403 colabomycin A from 21:403 Streptomyces griseolavendus 15:445; 27:869
Streptomyces griseolus 1:408;26:830 Streptomyces griseoplanus 10:104 Streptomyces griseoru-biginosus 21:405 Streptomyces griseoviridis 26:444;29:320 Streptomyces griseus 1:514;7:388; 18:700;19:587 ;21:304 ;22:80;23:474; 29:611 actinophage B 1 from 21:408 aplasmomycin from 21:304 Streptomyces griseus var. autrophicus 26:454,1123,1155 Streptomyces grisline 12:300 indolizomycin from 12:300 Streptomyces hagronensis 21:401 U-56407 from 21:401 Streptomyces hydroscopicus 21:388; 23:72;29:332 Streptomyces hygroscopicus subsp limoneus 13:223 Streptomyces hygroscopicus var. geldanus 21:437
Streptomyces hygroscopicus var.limoneus 29:480
Streptomyces incarnatus 19:177;26:830 Streptomyces kasugaensis 23:343 Streptomyces lavendulae 10:77-80; 21:266;25:825 ;29:332
Streptomyce lividans 26:1010 Streptomyces lusitanus 10:103 Streptomyces lydicus 14:105;21:411; 28:126;130 streptolydigin from 14:97,98,100 Streptomyces malachitofuscus 29:317 Streptomyces matensis 11:113;28:143 vineomycin A~ from 11:113 Streptomyces matensis subsp, vineus 5:594 Streptomyces mediocidicum 11:278 telocidines from 11:278 Streptomyces melanovinaceus 10:115, 19:289,340 Streptomyces miharaensis 1:404 Streptomyces mobaraensis 15:457 Streptomyces morookaensis 4:242 Streptomyces nigellus 23:61 Streptomyces nitrosporeus 29:339 Streptomyces noboritoensis 5:590 Streptomyces nodosus 4:513;23:343,347 amphotericin B from 6:261
1348
Streptomyces nodosus var. asukaensis 11:189;21:401 asukamycin from 11:189
Streptomyces nogalater
nogalamycin from 14:47 Streptomyces nourcei 22:58,80 Streptomyces novoguineensis 1:404; 22:273 Streptomyces OM-4842 5:597 Streptomyces orientalis 21:406 reductomycin from 21:405 Streptomyces oxamicetus 4:234 Streptomyces pactum 15:457 Streptomyces parvulus 21:403;28:135 manumycin A from 21:403 manumycin D from 21:403 Streptomyces phaechromogenes var ikaruganensin 28:138 Streptomyces phaeochromogenes 5:553; 18:10 Streptomyces plicatus 4:243,244 Streptomyces primprina 22:533 Streptomyces pulveraceus sp. 27:883 Streptomyces purpeofuscus 26:373 Streptomyces pyogenes 29:536 Streptomyces ramulosus 10:443 (-)-acetomycin from 10:443 Streptomyces refuineus 21:420 anthramycin from 21:420 Streptomyces rhishiriensis 11:189 ansatrienin (mycotrienin) from 11:189 Streptomyces rimoss 11:135;23:24,42,45 tetrangomycin from 11:135 tetrangulol from 11:135 Streptomyces rimosus var. paromomycinus 28:118 Streptomyces riseochromogenes 23:343 Streptomyces rishiriensis 23:75 Streptomyces rosa var. 0S-3966 11:127 Streptomyces roseopalvus 22:263 Streptomyces rugosporus 29:339 Streptomyces sapporonensis 12:63 bicyclomycin from 12:63 Streptomyces setonii 22:273,275 Streptomyces showdoensis 29:265 Streptomyces sp. M-193 12:365 Streptomyces sp. N-126 12:366,368
Streptomyces sp. PK-286C 12:366 staurosporine from 12:366
Streptomyces sp. RK-286 12:366 RK-286 C from 12:366
Streptomyces spectabilicus 20:796 Streptomyces spectabilis 21:430;23:3 streptovaricins A-G from 21:430
Streptomyces spiroverticillatus 18:269 tautomycin from 18:269
Streptomyces staurosporeus 1:3;5:55; 21:262 BMY-41950 from 12:366,368 indolo-2,3-carbazole alkaloids from 21:262 staurosporine ("AM-2228") from 12:365 Streptomyces strain 21:437;28:138; 29:328 AM-3672 from 21:437 herbimycin A-C from 21:437 Streptomyces subflavus subsp, irumaensis 5:597 Streptomyces tanashiensis 5:618 Streptomyces teryimanensis 12:300 indolizomycin from 12:300 Streptomyces thiolutens 21:420 mazethramycin A from 21:420 Streptomyces tirandis 3:270;21:411; 28:131 tirandalydigin from 14:97,98 tirandamycin A from 14:98;21:411 Streptomyces tolypophorus 23:56 Streptomyces toyocaensis 26:493 Streptomyces venezuelae 5:552;29:309 Streptomyces verticillatus 9:433-434 Streptomyces violaceoruber 4:255;
11:214,215;29:317
granaticin producer 11:214,215
Streptomyces virginiae 29:332 Streptomyces viridochromogenes 29:325 Streptomyces viridosporus 15:441 Streptomyces xanthochromogenus 21:405 reductomycin from 21:405
Streptomyces xanthocidicus 29:328 Streptomyces zelensis 1:180;3:310 Streptomycetes 29:477 Streptomycin sp. 21:410 Streptopelia chinensis suratensis 5:837 hemoglobin components of 5:837
1349
Streptopelia orientalis 5:837 hemoglobin components of 5:837 Streptosporagium sibiricum 26:1211 Streptoverticilium rimofaciens B98891 4:245 Streptoverticillium ardum 13:433 porfiromycin from 13:433 Streptoverticillium fervens 21:395 FR-900848 from 21:395 Streptoverticillium mobaraense 12:366, 370 BE-13793 C from 12:366,370 Streptoverticillium olivoreticuli 22:533 Streptoverticillium olivoreticuli subsp. neoenacticus 10:638 Streptoverticillium verticillus 19:351 Striga asiatica 30:162 infection with 30:162 Striga asiatica 5:823;9:364 Strobilurus tenacellus 22:249 Stronglyocentrotus purpuratus 25:813 Stronglyophora hartmani 15:312
Strongylocentrotus droebachiensis 7:285;15:104
Strongylocentrotus intrmedius 7:285 sulfated sterols from 7:285
Strongylocentrotus nudus 25:788 Strongylocentrotus purpuratus 15:104; 28:717
Strongyloides ratti 26:486 Strongyloides stercolaris 26:486 Strongylophora 25:690 Strongylophora durissima 21:275 strongylophorimis from 21:275
Strongylophora sp. 21:254.
meroditerpenoids from 21:254
Strphanthus gratus 25:537 Strurnus vulgaris 5:836
hemoglobin components 5:836
Strychnos 26:1030-1032,1035 Strychnos sp. 6:503 Strychnos alkaloids 16:435;26:10291031,1040,1049,1053,1054,1060, 1063-1065,1067 chemosensitizing activity of 26:1063 Strychnos atlantica 26:1050 Strychnos bifurcata 26:1034,1039 Strychnos camptoneura 26:1060
Strychnos cinnamomifolia 22:533 for epilepsy 22:533
Strychnos colubrina 26:1029 Strychnos decussata 26:1032,1035,1036 Strychnos dinklagei 6:503-536 alkaloids of 6:503-506 brafouedine from 6:503-506 cantleyine from 6:503-506 dinklageine from 6:522 ellipticine from 6:506 gentianine from 6:529 10-hydroxyellipticine from 6:509 18-hydroxyellipticine from 6:513 isobrafouedine from 6:503-506 8-methoxy-8,10-dihydrogentianine from 6:529 7-O-[4-methyl-5-(1-hydroxyethyl) nicotinoyl] strychnovoline from 6:522,527 monoterpene alkaloids from 6:522-527 oxidizing enzymes in 6:520 N-b-oxy- 17-oxoelipticine from 6:513,515 strellidimine from 6:516 venoterpine from 6:527 Strychnos diplotricha 26:1034,1038 Strychnos divaricans 26:1055 Strychnos floribunda 26:1032 Strychnos gossweileri 1:125 Strychnos grossweilleri 26:1060 Strychnos guianensis 26:1055 Strychnos henningsii 26:1032,1039,1035 Strychnos longicaudata 1:124 Strychnos madagascariensis 26:1033, 1035 Strychnos melinoniana 1:124,125 Strychnos mitis 26:1033 Strychnos monoindole 26:1061 anticancer/protozoal 26:1061 istonine 26:1061 cryptolepine 26:1061 5,6-dihydroflavopererine 26:1061 harmane 26:1061 matadine 26:1061 melinonine 26:1061 noimrelinonine 26:1061 serpentine 26:1061 strychnoxanthine 26:1061
1350
Strychnos mostueoides 26:1034,1035 Strychnos myrtoides 26:1034,1035,1038, 1039,1050,1053,1065 Strychnos ngouniensis 1:124 Strychnos nux vomica L. 26:143,1029 ; 27:780 cantleyine from 6:503 Strychnos panganensis 26:1033,1052, 1055 Strychnos pentantha 26:1034,1039 Strychnos potatorum 26:1031,1032,1036 Strychnos sp. 26:1032-1034 alkaloid of 26:1032-1034 Strychnos spinosa 26:1033 Strychnos toxifera 26:143 Strychnos trichoneura 26:1034 Strychnos usambarensis 1:124,126; 26:1060,1063 Strychnos vacacoua 6:503 bakankoside from 6:503 Strychnos vomica 26:1052 Sturmus pagodarun 5:837 hemoglobin components of 5:836 Stylissa carteri 25:712,791 Stylocheilus longicauda 17:4,104,19:549 Styloguanidines 25:784 Stylophora pistillata 28:646 palythrine-threonine-sulfate from 28:646 Stylophorum diphyllum 27:159 Stylophorum genera 27:163 Stylophorum lasiocarpum 27:159 Stylopus australis 28:704 Stylosanthes hamata 28:399 against Boophilus microplus 28:399 Stylosanthes humilis 28:399 against Boophilus microplus 28:399 Stylosanthes scabra 28:400 Stylosanthes sp. 400 Stylotella agminata 25:770 Stylotella aurantium 21:351,356,366,367; 25:113,783,784 Stylotellane B 25:783 Stypopodium 25:691 Stypopodium flabelliforme 28:432
Stypopodium zonale 5:439;6:54;21:275 stypodiol from 6:54 stypoldione from 6:54 Stypopodium-flabelliforme 25:690 Styracaster 25:872 Styracaster caroli 15:75,76 carolisterol A-C 15:75,76 Suberea creba 25:719 Subergorgia suberosa 13:26 Subulitermes bailey 14:451,452 eudesm- 11-en-4-ols from 14:451 neointermedeol from 14:451,452 Subulitermes oculatissimus 14:451 neointermedeol from 14:451 Subulitermes parvellus 14:451 neointermedeol from 14:451 Sucupira branca 29:103 Suillus 29:271 Sulfobus solfataricus 25:720 Supella longipalpa 22:377 Sustantia nigra 22:24 Swainsona canescens 12:313 ;27:515 (-)-swainsonine from 12:313 Swainsona galegifolia 27:255 Swainsona sp. 7:11;10:558;27:514 Swartzia madagascariensis 7:417,427, 429,431,432 Swartzia pickellii 29:606 Swartzia simplex 7:427,429 Swertiajaponica 22:533;25:476 Swertiaperennis L. 22:533 Swertia purpurascens 22:533 Swertia randaiensis 22:533 Swertia sp. 25:471 Swietenia mahagoni 25:943 Sylibum marianum 22:428,431,440 Symbiodinium sp. 25:722 Symphacia obvelata 26:463,471,478,493 Symphomyrtus subgenus 24:233 euglobals of 24:233 Symphonia globulifera 22:659 Symphytum 29:582 Symphytum officinale 9:60-62;21:670; 28:400 saponins from 9:60-62 Symploca hydnoides 25:887
Symplocos helminthosporium carbonum 27:498
1351
Symplocos lancifolia 27:17,33, 34 phlorizin from 27:17,33,34 Symplocos microcalyx 27:17,34 trilobatin from 27:17 Synaptolepis kirkii 22:533 for epilepsy 22:533 Synechococcus leopoliensis 26:359, 362-364 Synechococcus sp. 21:304,305 Synechocystis PCC 26:6803 26:366 Synechocystis trididemni 10:251 Synoicum prunum 25:723 Syringa 26:327 Syzygium carynocarpum 29:708 Syzygium malaccense 29:708 Tabebuia avellanadae 5:16;15:385; 27:851 Tabernaemontana ciliata 5:83 Tabernaemontana divaricata 9:166-168 Tabernaemontana eglandulosa 5:109 Tabernaemontana orientalis 5:70 Tabernaemontana pachysiphon 5:110 Tabernaemontana rigida 5:107 Tabernaemontana sp. 5:69-70,83,84,86, 89,93;9:164,165 indole alkaloids 5:69-134 Tabernaemontana spp. 22:533 Tabernanthe iboga 22:533 Tachytes guatemalensis 5:223,253 Tagetes erecta 21:600 Tagetesfilicifolia Lag. 27:16 trans-anethole from 27:16 Tagetes filicifolia. 27:16 Tagetes filifolia 21:618 Tagetes sp. 26:437 Taiwania cryptomeriodes 26:232 helioxanthin from 26:232 Taiwania cryptomeroides 17:333;28:418 Talaromyces flavus 21:239 Talaromyces stipitatus 14:531 talaromycin A and B from 14:531 Talaromyces wortmannii 27:858 Talinum tenuissimum 7:427,435 Talisopine 534,542 Tamarix articulafa 22:533 for epilepsy 22:533 Tamarix articulata 22:533
Tamarix gallica L. 22:533 for epilepsy 22:533 Tamus communis 17:130,132 Tanacetrum vulgare 7:94,95,98,101,102, 108,109,112,120 Tanacetum albipannosum 27:570,590 Tanacetum annuum 27:575 Tanacetum argenteum 27:551,565,579 Tanacetum argyrophyllum 27:555 Tanacetum aucheranum 27:586,587 Tanacetum balsamita 27:551,591 Tanacetum chiliophyllum 27:551,556 Tanacetum cilicium 27:575 Tanacetum cinerariaefolium 27:551,571 Tanacetum corymbosum 27:586 Tanacetum densum 27:551 Tanacetum ferulaceum 27:549 Tanacetum heterotomum 27:590 Tanacetum indicum 27:575 Tanacetum microphyllum 27:564,574; 29:89,703 Tanacetum odessanum 27:586 Tanacetum parthenifolium 27:581 Tanacetum parthenium 7:119,120; 24:849;27:548,566,856;29: 88,686, 703;30:206 active anti-migrane principle in 24:849 in treatment of migraine 30:206 Tanacetum poteriifolium 27:560 Tanacetum praeteritum 27:549 Tanacetum pseudoachillea 27:557 Tanacetum ptarmicaeflorum 27:558,567 Tanacetum santolina 27:550,555,566 Tanacetum santolinoide 27:551,567 Tanacetum serotinum 27:550 Tanacetum sinaicum 27:553 Tanacetum sp. 27:634,547 allergent activity of 27:634 anticoagulant and antifibrinolytic activity of 27:635 antihelmintic activity of 27:636 antiinflammatory activity of 27:637 antiulcer activity of 27:639 biological activities of 27:547 cytotoxic effects of 27:639 insecticidal activity of 27:641 phytochemical studies of
1352 27:548-594 phytotoxic activity of 27:643 prophylactic activity against migraine 27:643 Tanacetum tanacetioides 27:555 Tanacetum vulgare 11:221 ;27:548,549; 28:426;29:703 Tanichthys alobonubes 25:794 Taonia atomaria 6:54;21:275;25:249 taondiol from 6:54 Tararomycin stipitatus 3:262 Taraxacum officinale Wigg. 27:215; 28:424;29:586 Targionia hypophylla 2:278 Taricha torosa 18:724 Tathy lyncurium 25:718 Tatraclinis articulata 25:246 Taveniera abyssinica 26:473 Taxodium distichum 14:667 taxodione from 14:667 Taxopneustes pileolus 7:283-285 Taxus baccata 11:61,20,79,80,112, 116,118;22:533;25:245 10-deacetylbaccatin III from 11:61 abscessic acid from 10:118 betuloside from 20:111 escholtzxanthine 20:118 for epilepsy 22:533 isotaxiresinol from 20:108 secoisolariciresinol from 20:108 taxiresinol from 20:108 taxicatin from 20:116 Taxus brevifolia 7:416;11:5,12:180; 20:140;22:717;24:269;25:244,245; 26:112 brevitaxin from 26:212 diterpenes of 7:416 taxol from 11:5,12:180 Taxus canadensis 20:107 canadensiene from 20:107 Taxus chinensis 20:107 Taxus cuspidata 20:80 Taxus cuspidata var. nana 24:276,278 Taxus floridata 20:81 Taxus mariei 20:108 et-conidendrine from 20:108 kojic acid from 20:118 Taxus media 20:81
Taxus sp. 20:79-123;24:270-276 chemical constituents of 20:79-123 Taxus wallichiana 20:107;22:533 wallifoliol from 20:107 Tebebuia chrysantha 4:388 naphthopyrans from 4:388 Tecoma araliaceae 29:722 Tecoma stans 26:1010 Tecona grandis 4:388 naphthopyrons from 4:388 Tedania ignis 19:558;25:814,828,896 Tegolophus australis 28:423 Teleogryllus commodus 5:815,830,831 Telesto riisei 1:687 punaglandin from 1:687 Tenebrio molitor 22:386,393 Tephrosia luninifolia 29:785 Terminalia alata 7:134 arjunolic acid from 7:134 maslinic acid from 7:134 maslinic lactone from 7:134 oleanolic acid from 7:134 terminolic acid from 7:134 Terminalia arjuna 7:133 arjunosides I-IV from 7:133 terminic acid from 7:133 terminoic acid from 7:133 Terminalia bellerica 26:228,231 anolignan B from 26:231 anolignan B from 26:224 termilignan from 26:224,231 thannilignan from 26:224 Terminalia chebula 22:533 for epilepsy 22:533 Terminalia genera 27:755 Terminalia siricia 7:132 siricic acid methyl ester from 7:132 Terminalia tomentosa 7:134;23:515 Terminalis sp. 7:133-135 triterpenes of 7:133-135 Terron phoenicoptera 5:837 hemoglobin components of 5:837 Terulopsis petrophilum 21:758 Tessaria dodoneifolia 15:31 ;27:17,34,35 dihydroquercetin 3-O-acetate 4'methyl ether from 27:17,34
1353
(2R, 3R)-dihydroquercetin 3-0acetate from 27:17,34 Tethys fimbria 19:552 nudibranch 19:551 Tetradium glabrifolium 27:164 benzophenanthridine alkaloids in 27:164 Tetrahymena pyriformis 2:294;23:71 Tetrahymena thermophilas 2:306; 4:268;23:216 1 (2,3,4,6-tetra-O-benzoyl-13glucopyranosyl)-2-pyriidine 4:224 Tetrameles nudiflora 22:533 for convulsions 22:533 Tetramorium caespitum 5:235,254 2,5-dimethyl-3-ethyl-pyrazines from 5:223 2,5-dimethyl pyrazines of 5:222 methyl pyrazines from 5:222 Tetramorium impurum 5:235,254 2,5-dimethyl-3-ethyl-pyrazines from 5:223 2,5-dimethyl pyrazines of 5:222 methyl pyrazines from 5:222 Tetranichus mites 28:433 neem extracts against 28:433 Tetranichus urticae 28:434 Tetranychus 28:428 Tetranychus urticae 1:702;28:424,425 Tetrapanax papyriferum 22:96 Tetraplaura tetraptera 7:434;21:660,673; 22:534 as anticonvulsant 22:534 Tetraponera sp. 6:451 Teucrium alyssifolium 633 Teucrium arduini 30:255 cirsimaritin 4'-glucoside from 30:255
Teucrium botrys 618 Teucrium chamaedrys 23:618 Teucrium divaricatum 23:632 Teucrium flavum 23:621 Teucrium fruticans 7:119;23:630 Teucrium gnaphalodes 23:614,619 Teucrium heteropyllum 23:636 Teucrium japonicum 23:601 Teucrium kotschyanum 23:601 Teucrium lanigerum 23:598
TeHcl"lHm massiliense 23:614
Teucrium micropodioides 23:616 Teucrium oliverianum 23:626,623 Teucrium pestalozzae 23:621 Teucrmm polium 21:584;23:598,633 Teucrzum pumillum 23:645 Teucrium pyrenaicum 23:618 Teucrium scorodonia 23:598 Teucrtum sp. 23:591;26:172;29:687;30:255 antiseptic agent 23:642 astringent agent of 23:642 carminative agent of 23:642 diaphoretic agent of 23:642 diuretic agent of 23:642 stimulet agent 23:642 tonic agent 23:642 Thadiantha grosvenorii 15:22 Thalassiosira weissflogii 25:731 Thalassoma bifasciatum 25:787 Thalictrum 25:180 Thalictrum foliolosum 22:534 Thalictrum isopyroides 22:534 Thalictrum minus var. microphyllum 22:534 Thalictrum rugosum 22:534 Thapsia sp. 25:536 Thapsia villosa 18:685 Thaumatococcus daniellii 15:5;27:19 thaumatin from 27:19 Thea sinensis 19:247 Theileria 26:804 Thelenota ananas 7:272;28:593 thelothurin A from 7:273 theothurin B from 7:273 Thelephora ganbajun 29:279 Theobroma cacao 21:534;29:606 Theoneila swinhowe 26:1176-1178,1180, 1186-1191,1194,1196,1197,1200 Theonella conica 26:1189 Theonella cupola 26:1190 Theonella mirabilis 26:1191;28:716 Theonella sp. 5:355,364;21:393;414; 25:714,715,771,772,775,878,884, 892,900;26:1175,1176,1179,1181, 1184,1188,1193,1198-1200,1212, 1217;28:682;710 aurantoside A and B from 21:414 Theonella sponges 28:681 keramamides F from 28:681
1354 theonellapeptolide congener from 28:681 thiazole-containing cyclic peptides 28:from 28:681 Theonella swinfoei 5:356,396,20:894, 896,589;28:136 Therioaphis maculata 8:221 germacrene-A from 8:221 Thermococcus tadyiricus 25:842 Thermoplasma acidophilum 26:1155 Thermopsis chinensis 15:523 (+)-5,6-dehydrolupanine from 15:523 Thermopsis lupinoides 15:523 (+)-lupanine N-oxide from 15:523 Thespesia populnea 27:855 Thladiantha grosvenorii 15:5 Thopsentia sp. 26:464,466 Thorecta choanoides 15:312;25:694 Thorecta sp. 5:410 Thorectandra excavatus 18:717 Thorectopsamma xana 25:844 Thromidia catalai 7:299;15:46 thornasteroside A from 15:45 Thuidiaceae 29:321 Thuja occidentalis 2:402,20:16 Thuja orientalis L. 20:16;22:534 for convulsive disorders of children 22:534 Thujaplicata D. 5:476;14:389,390; 16:269;17:338;23:343 ;26:188;27:384; 28:408 thujone from 14:389,390 Thuja standishii 29:87,101 Thujia orientalis 8:3 essential oil from 8:3 Thujopsis 26:172 Thujopsis dorablata 21:621;29:583 Thujopsis plicata 29:583 Thujopsis sp. 21:615 Thuya occidentalis 21:617 Thymbra spicata 30:272 luteolin from 30:272 Thymus piperella 30:263 luteolin 7-glucoside from 30:263 Thymus sp. 21:598;26:172,746;29:579 Thymus vulgaris L. 21:599,617,619,621; 27:374 ;28:390;391,415 Tibouchina semidecandra 23:404,405
Tilapia mossambica 5:370 Tilapia nilotica 7:183,185,187 Tilia chordata 22:679 Tilia sp. 21:537 Tilletiopsis sp. 5:291 Tinea pedis 474 Tiphia sp. 5:225,253 Tithonia diversifolia 29:90 Toddalia 27:164 Toddalia aculeata. 27:158,164,177 Tolypathrix nodosa 25:691 Tolypocladium geodes 21:225 peptaibols from 21:225
Tolypocladium inflatum 21:225;22:257 Tolypocladium niveum 21:225,227 Tolypocladium niveus 26:486 Tolypothrix nodosa 21:275;29:100 Topsentia sp. 25:704;28:701 in guanosine diphosphate/G-protein RAS exchange assay 28:701 sulfates of 28:701 topsentiasterol sulfate A from 28:701 topsentiasterol sulfate B from 28:701 topsentiasterol sulfate C from 28:701 topsentiasterol sulfate D from 28:701 topsentiasterol sulfate E from 28:701 Topsentia sponge 27:861 Torpedo califronica 18:721 Torresea acreana 29:599 Torulopsis colliculosa 5:283,292 Torulopsis glabrata 25:258 Torulopsis gropengiesseri 5:293 Torulopsis lactis-condensi 5:293 Torulopsis magnoliae 5:293 Torulopsis sp. 5:292;21:758 Tovomita krukovii 29:578 Toxadocia cylindrica 28:711 Toxiclona toxius 28:675 toxicol A from 28:675 toxiusol from 28:675 Toxocara canis 17:379;24:714; 26:470,471,474,887 Toxocara mystax 26:471 Toxoplasma 26:783,804
1355
Toxoplasma gondii 13:183;26:835 Toxotrypana curvicauda 5:239,252 2-methyl 6-vinyl-pyrazines of 5:222 Trachelospermum asiaticum Nakai var intermedium 5:505,515,521,526,545 Trachelosperum jasminoides 26:233 arctigenin from 26:233 matairesinol from 26:233 nortrachelogenin from 26:233 trachelogenin from 26:233 Trachycladus laevispirulifer 25:775 Trachylobium verrucosum 25:252 Trachyopsis aplysinoides 28:660 Trachyopsis halichondroides 25:70; 428:700 26-norsokotrasterol sulfate from 28:700 Tradescantia multiflora 25:382 Tragacantha Bunge 27:444 Trametes cinnabarma 26:1012 Trapajaponica 23:405 Trapa quadrispinosa 24:273 Traxacum officinale 25:391 Trema guineensis 22:534 for epilepsy 22:534 Trema orientalis 22:534 of epilepsy 22:534 Tremella mesenterica 5:288,289,307 Tremella sp. 5:288 Trewia nudiflora 23:70 Tribolium castaneum 9:299;21:612;23:66 Tribolium confusum 24:101 Tribophyton mentagrophytes 21:758 Tribulus terrestris 24:273;26:259 tribulusamide A from 26:259 tribulusamide B from 26:259 Tricellaria ternata 17:92 Trichia floriformis 29:232 as myxomycete species 29:232 arcyriaflavin B from 29:232 2,4-dihydroxynaphto-quinone chromophore of 29:232 Trichia varia 29:236 Trichilia emetica 20:492,493 Trichilia glabra 30:411 anti-polio virus activity of 30:411 Trichinella spiralis 22:401 ;26:483 Trichocolea tomentella 2:278
Trichocoleopsis sacculata 2:278,279 Trichocoleopsis sp 2:90 Trichoderma hamatum 21:240 Trichoderma harzianum 8:352;21:197, 198,199,201,213,214,227,223,225,233 cyclonerodiol from 21:226,227 harziandione from 21:209,234 harzianins HA from 21:225 tetramic aicd from 21:216 4-thiocellobiose from 8:352 trichoharzin from 21:211 trichokindins from 21:225 trichorozins from 21:225 trichorzianines from 21:225 Trichoderma koningii 21:198,229 cyclonerodiol from 21:226 gliodeliquescins from 21:225 ergokonin A and B from 21:237 heptelidic acid from 21:229 tricho-acorenol from 21:231 trichokonins from 21:225 trikoningins KA from 21:225 trikoningins KB from 21:225 Trichoderma koninogii 21:231 Trichoderma lignorum 8:352;21:182 xylanases from 8:352 Trichoderma longibrachiatum 21:206, 212,225;25:725 Trichoderma polysporum 21:212,227 polysporins from 21:225 tetrahydrofura analogues from 21:227 trichosporins from 21:225 trichopolyns from 21:225 Trichoderma pseudokoningii 21:225 harzianins HK from 21:225 Trichoderma reesei 8:348,351,21:225; 23:128;25:308 cellobiohydrolases from 8:348,351 cellobiohydrolase A from 8:351 cellobiohydrolase B from 8:351 Trichoderma saturnisporum 21:225 saturnisporins from 21:225 Trichoderma sp. 5:368;7:406;21:191,196198,202,203,212,213,215,221,223, 224,226,227;25:155;26:482,1128 Trichoderma virens 21:232 4-thiocellobiose from 8:352
1356 Trichoderma viride 21:191,197,212, 221,223,225,229,234,237 ergokonin A and B from 21:237 trichodermin from 21:232 trichotoxins from 21:225 suzukacillins from 21:225 Tricholma giganteum 23:126,134 Trichomans vaginalis 22:625 Trichommonas foetus 2:293 staurosporine against 12:397 Trichomonas gallinae 2:294 Trichomycetes 22:246 Trichophyto rubrum 26:1159 Trichophyton granulosum 5:294 Trichophyton interdigitale 5:294,298, 598;12:401 Trichophyton mentagrophytes 2:446; 12:401 ;20:28,30,31 ;21:602; 22:627,628 ;23:199;25:780;26:227, 673 isomagnolol 26:227 magnolol 26:227 Trichophyton mentagrophytes KCH 1155 28:476 Trichophyton rubrum 5:294,236,12:401, 21:602;22:627 Trichophyton schonleinii 5:294 Trichophyton sp. 5:294,328;21:396; 26:1127,1128 Trichophyton tonsurans 12:401 Trichoplusia 5:832 Trichormus var. P-9 26:359 in agar-diffusion assays 26:359 Trichosanthes anguins L. 22:534 for epilepsy 22:534 Trichosanthes kirilowii 13:655,660; 22:124 Trichosporon aculeatum 5:283,292 Trichosporon cutaneum 5:292,294 Trichosporon fermentans 5:292 Trichosporon inkin 5:294 Trichosporon sericeum 5:294 Trichosporon sp. 5:292;25:150 Trichosporon undulatum 5:294 Trichostrongylus colubriformis 26:429, 440,443,453,461,472,484,490,491; 28:349 Trichothecium 21:233;26:464 Trichothecium roseum 10:307;29:88
Triclisia sp. 26:824 Tricophyton mentagrophytes 9:297; 26:228
Tricophyton rubrum 26:228 Tridacna crocea 23:178 Tridacna maxima 28:652 arsenic-containing sugar sulfate 28:from 28:652 Tridentata marginata 25:896;28:646 tridentatol A from 28:646 tridentatol B from 28:646 tridentatol C from 28:646 Trididemnum cyanophorum 4:102;5:427, 428;10:244,250,251,252,262,294 Trididemnum palmae 10:252 Trididemnum solidum 4:102;10:245, 250,252,253;25:118 Trididemnum sp. 5:422;10:245;12:303, 477;21:252;25:819,820;28:638 didemnine A from 12:477 didemnine B from 12:303 from Guam 28:638 shermilamine A from 28:638 Tridiemnum genus 17:23 Triflouim sp. 25:667 Trifolium repens 26:696 Trifolium subterraneum 29:577 Trigonella foenumgraecum 21:671;
26:1139,1141,1268;27:277;28:425 Trillium glycosides 2:443 antifungal activity of 2:443
Trillium grandiflorum 2:443;23:343 Trillium smalii 21:662 Trillium tschonoskii 2:443 Trimusculus reticulatus 17:27 Trinervitermes bettonianus 21:277 Triphophyllum peltatum 26:813,822 Tripneustes gratilla 7:283,284 Triptergium wilfordii Hook F 29:198,199
Tripterospermum lanceolatum 27:902 Tripterygium doianum 30:654 3 [3-acetoxy-11-ursen- 13c~,30-olide from 30:654 Tripterygium hypoglaucum 30:646,654 hypodiol from 30:646 triptohypol Dfrom 30:654 Tripterygium regelii 23:696
1357
Tripterygium wilfordii 2:403,404,414, 416;7:146;18:771 ;22:109,137;132; 23:660;29:99;30:639,641,648,664, 676,689,690
3,5-di-tert-4-hydro xy-Nisobutylbenzamide as 29:24 4-phenylamino- 1,2,3,4tetrahydroquinolines as 29:24 RG-102240 (GS-E) as 29:23 RH-0345 (halofenozide) as 29:23 RH-2485 (methoxyfenozide) as 29:23 RH-5992 (tebufenozide) as 29:23 213,313,20R,22R-tetrahydroxy-25fluoro-5 [3-cholest-8,14-dien-6-one as 29:18,19 2a,3 [3-dyhdroxy-olean- 12-ene22,29-1actone from 30:648 2 [3,2213-dihydroxy-3,21-dioxo-24carboxyl-29-nor-friedelan methyl ester from 30:641 6a-hydroxytriptocalline-A from 30:641 as anti-AIDS agent 30:639 as anticancer 30:639 as insecticide 29:22;30:639 as traditional medicine 30:689 bisacylhydrazines as 29:22 celastrol from 30:664 disadvantages of 29:22 for rheumatoid arthritis treatment 30:689 for spondylitis treatment 30:689 in gene switch systems 29:23 in treatment of rheumatoid arthritis 30:639 in treatment of spondylitis 30:639 inhibitory effects of 30:690 maocrystal as 29:23,24 nonsteroidal 29:22 pristimerin from 30:664 QSAR studies of 29:22 tissue culture of 7:146 triterpenes of 7:146 triptocallic acid D from 30:648 wilforic acid A from 30:676 Tripterygium wilfordii var. regelii 30:639,642
regelone from 30:642 regeol B from 30:639 Triticum 9:321 Triticum aestivum 18:503,512,520,19:247; 27:188,191,193,215,217,218;29:585, 613 3-dehydroteasteron from 18:500 Triticum BBI 29:600 Triticum vulgare 9:321 Tritonia crocosmaeflora 23:96 Tropilaelaps clareae 28:387 Trychostrongylus 26:425 Trypamosoma 18:791,793 Trypanasoma dionisii 18:801-804 Trypanasoma verpertillionis 18:801,804 Trypanosoma berghei gambiense 26:785787,791,792,828 Trypanosoma berghei brucei 26:791,797 Trypanosoma brucei rhodesiense 26:785787,791,792,825 Trypanosoma burcei 18:448,449;28:148 polysaccharides of 2:310 Trypanosoma congolense 26:785 Trypanosoma conorhini 2:311 Trypanosoma cruzi 18:796-802;23:137,473~ 24:818,819;26:230,673,787,788, 792,793,797,799,801,802,813,819, 822,828;28:148;29:748 glycosphingolipids 18:796-802 glycocomplexes of 2:302-309 Trypanosoma mega 18"804 glycocomplexes of 2:310,311 polysaccharides of 2:310,311 Trypanosoma spp. 2:301-310;26:786, 779,780,785,786, 797,800,803,806808,810,822,824,828,838 glycocomplexes of 2:301-310 polysaccharides of 2:301-310 Trypanosoma vivax 26:785 Tubastraea aurea 5:359 Tubastrea micrantha 5:360 Tubipora musica 24:119 Tubulanus punctatus 18:725 Tulipa gesneriana 19:247 Turbatrix aceti 26:481 Turbo connutus 7:270 mixed glucosidase from 7:270 Turdoides somerville 5:837 hemoglobin components of 5:837
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Turus migratorius 5:836 hemoglobin components of 5:836 Tutufa lissostoma 18:724 Tylenchulus semipenetrans 26:456,469 Tylophora hirsuta 12:300 phenanthroindolizidine alkaloids from 12:300 Tylophora sp. 1:360 Typha latifolia 19:247;26:358,361 Typhlodromus urticae 28:430 asimicin from 28:430 desacetyluvaricin from 28:430 squamocin from 28:430 Tyromyces sambuceus 21:197 Tyrophagus putrescentiae 28:421 against 1,8-cineole 28:421 against fenchone 28:421 against isomers of caryophyllene 28:421 against linalool 28:421 against linalyl 28:421 against menthone 28:421 against myrtanol 28:421 against pinene 28:421 against pulegone 28:421 against (x-terpinene 28:421 against ~,-terpinene 28:421 against terpineol 28:421 against valencene 28:421 Uca pugilator 19:628 Udotea flabellum 16:312 Ulmus thomasii 17:338 Ulva lactuca 7:338;30:408 (6S,6'S)-r162 from 7:338 anti-influenza activity of 30:408 Ulva perfusa 21:305 Ulva sp. 25:725 Umbelliferae genera 27:361,686 Umbilicaria angulata 5:311 Umbilicaria caroliniana 5:311 Umbilicaria polyphylla 5:311 Umbraculum mediterraneum 25:831; 28:650 Umezakia 26:352 Uncaria genus 17:122 Uncaria guaianensis 17:116,124;22:363
Uncaria rhyncophylla 22:534 as convulsions in children 22:534 Uncaria tomentose 22:362 Ungernia minor 26:616 Uromyces phaseoli 9:220 Urospora penicilliformis 26:1137 Urtica dioica L. 29:697 Usnea rubescens 5:310 Usnea sp. 5:311,313 Ustilago maydis 22:263;25:389 Ustilago sp. 9:203 Uvaria accuminata 17:251 uvaricin from 18:193 Uvaria narum 18:221 isodencetyl uvaricin from 18:221 Uvaria pauciovulata 28:422 Vaccaria segetalis 26:27,28,29,50,56 vaccarosides A-H from 26:27-30,56 Vaccinia 27:873 Vaccinium angustifolium 23:782 Vaccinium corymbosum 29:585 Valeriana hardwickii 22:534 for epilepsy 22:534 for hysteria 22:534 for hysteroepilepsy 22:534 Valeriana jatamansi 22:534 Valeriana leshchenaultii 22:534 Valeriana officinalis L. 6:524;22:534; 26:270 for epilepsy 22:534 for hysteria 22:534 for hysteroepilepsy 22:534 (+)-l-hydroxypinoresinol from 26:270 monoterpene alkaloids from 6:524 (+)-pinoresinol-[3-D-glucoside from 26:270 (+)-pinoresinol from 26:270 (-)-prinsepiol from 26:270 Valeriana wallichii 22:534 for epilepsy 22:534 for hysteria 22:534 Valsa ceratosperma 15:385 5-methylmellein from 15:385 Vancouveria hexandra 29:788 Vanilla planifolia 25:126
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Vanillomopis arborea 29:89 Vantanea peruviana 29:708 Varroajacobsoni 28:387 honey bees tolerant to 28:387 toxicity of 28:387 Varroa jacobsoni 28:393 Varroa mites 28:383,384,392 as honey bee parasites 384 biological activity of 28:392 Vatica affinis 23:538,547 Vatica diospyroides 23:533,538,547 Vellozia candida 20:474 rosane diterpenoids of 20:474 Velocitermes velox 14:451,452;27:385 from Peru 27:385 (+)-intermedeol from 14:451,452 Venetian lagoon 28:702 Venturia inequalis 21:217;22:459 Vepris lousii 2:121 Veratrum 23:563-589 embryonic development of 23:563-589 Veratrum album 23:569 Veratrum alkaloids 7:16,20-22 Veratrum califormicum 7:16 steroidal alkaloids from 7:16 Veratrum californicum 23:564,568,569 Veratrum nigrum L, 22:534 in convulsions 22:534 Veratrum sp. 21:97 Verbasum thapsus L. 22:535 in infantile convulsions 22:535 Verbesina 26:437 Verbesina rupestris 16:131 Vernonia amygdalina 26:808;28:400 tick toxicity of 28:400 Vernonia brachycalyx 26:798,811 Vernonia chinensis 22:535 in convulsions in children 22:535 Vernonia galpinii 5:728 Vernonia hildehrandtii 22:535 in convulsions in children 22:535 Vernonia patula. 22:535 Verongia sp. 10:632 Verongia spengelii 5:410 Verongula gigantea 25:721 Veronica persica 25:781 Verticillium alboartrum 25:299,302,307, 311
Verticillium balanoides 27:868 Verticillium biguttatum 21:205 Verticillium dahliae 21:205,239; 25:305,307,311 Verticillium lecanii 28:404 Verticillium sp. 21:221 Vesiscular stomatitis 25:779 Vespa orientalis 4:494,19:133 Vetiveria zizanioides 27:377 Vibrio algmolyticus 26:70 Vibrio anguillarum 23:164,238;25:877 Vibrio cholerae 4:195;25:521 Vibrio ganera 29:311 Vibrio ordalii 4:195 tetraheptoses in 4:195 Vibrio sp. 21:259,310 Vibrio valnificus 25:718 Vibumium dilatatum 4:712 Viburnum awabuki 26:255 9'-O-(-)-phlligenin from 26:255 vibsanol from 26:255 Viburnum suspensum 25:251,257,259 Vicia angustifolia 29:599 Viciafaba L. 19:247;23:341;25:93; 26:748;27:218;29:609 Vicia sativa 25:93;29:591 Vicoa indica 29:89 Vietnamese ginseng 21:672 Vigna angularis 25:93;29:609 Vigna radiata 18:522 23-O-13-D-glucopyranosyl brassinolide from 18:522 Vigna unguiculata 25:93;29:617 Viguiera gardneri 29:90 Viguirea aspillioides 26:810 (-)-trachyloban- 19-oic- from 26:810 Villagorgia rubra 21:260 Vinca major elegantissima 1:124 Vinca minor 2:370;26:144;29:573 (-)-eburnamonine from 8:283 (+)-vineamine from 8:283 Vinca rosea (Catharanthus roseus) 24:269 Virgilia 26:1157 Virola elongata 17:319;22:356 Virola oleifera 26:228 3,4,3',4'-tetramethoxylignan-7-ol from 26:228 oleiferin-B from 26:228
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oleiferin-F-from 26:228 oleiferin-G from 26:228 Virola sebifera 18:726;22:356;26:186 Virola surinamensis 26:230 grandisin from 26:230 veraguensin from 26:230 Vismia 22:580 Vismia decipiens 4:378 Visnea mocanera 21:548 Vitex lucens 29:579 Vitex negundo 22:535 for convulsions in children 22:535 Vitex peduncularis 29:84 Vitex rotundifolia 29:101 Vitis vinifera 20:721,723,724,731; 21:204 ;26:530;27:756,757 ;29:585 Viverra civetta 8:219 Voacanga thouarsii 22:535 Volucrispora aurantiaca 29:266 Volvariella volvacea 5:287,288,290, 316,320;23:115
Wachendorfia 17:372 Waitzia acuminata 25:251 Waksmania aerata 27:219 Warabi 26:691 Warbugia stuhlmannii 17:234 Warbugia ugandensis 17:234 Warburgia stuhlmanii 4:403,427;24:182 Warburgia ugandensis 4:403,427;22:635; 24:182 Watersipora subtorquata 28:620 5,7-dihydroxy-6-oxo-6H28: anthra[ 1,9-bc] thiophene- 1carboxylic acid from 28:620 Wedelia asperrima 20:8 Wedelia glauca 20:8 Wedelia paludosa 26:810 ent-kaura- 16-en- 19-oic acid from 26:810 Wedelia scaberrima 7:427 Wiesnerella denudata 2:280 Wikstroemia indica 26:270;27:833 (+)-nortrachelogenin from 26:270 Wistaria brachybotrys 24:221,223,224, 241,247,261 Wistaria brachybotrys 21:642;25:93,222 Wisteria floribunda 24:273
Withania ashwagandha 22:535 Withania coagulans 20:238 Withania somnifera L. 20:138,180,181, 234,238,241,246,247 ;22:535 as antiepileptic 22:535 as sedative in epilepsy 22:535 Woodfordia fruticosa 23:404 Wurmbea sp. 6:158 synthesis of 6:158 xanthophils 6:158 Xanathomonas adaptation 25:399 Xanthium spinosum 25:781 Xanthium strumarium 27:346 Xanthocephalum linearifolium 25:251 Xanthoceras sorbifolia 7:139,141 ;29:575 triterpenoids of 7:139,141 Xanthocercis zambesiaca 24:917,918 Xanthomonas 26:582,605 Xanthomonas c. pv. armoraciae 26:596 Xanthomonas c. pv. carotae 26:596 Xanthomonas c. pv. orizae 26:596 Xanthomonas c. pv. raphani 26:596 Xanthomonas campestris 5:314;12:401; 26:596,1154;29:545 Xanthomonas campestris pv. vitians 26:596 Xanthomonas compestris pv. vesicatoria 25:399 Xanthomonas fragariae 26:596 Xanthomonas hortorum campestris pv. vitians 26:596,606 Xanthomonas maltophilia 23:474 Xanthomonas oryzae 12:398;25:395,398 carboxylate against 12:398 Xanthones 27:902 Xanthoxylon hostile 22:535 for epilepsy 22:535 Xenia 25:690 Xenopus laevis 8:435;27:805 13-thymosin from 8:435 thymosin [~4xen8:435 Xenopus oocyte 15:451 Xenorhabdus nematophilus 15:389 xenocoumacins from 15:389 Xenorhabdus spp. 15:381 Xerocosmus 29:271 Xeromphis spinosa 7:427
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Xestospongia ashmorica 21:262;25:710 [3-carboline alkaloids from 21:254 Xestospongia carbonaria 25:861 ;28:677 Xestospongia exigua 15:312;17:33;21:267 xestospongin A from 21:267 xestospongin B from 21:267 xestospongin C from 21:267 xestospongin D from 21:267 Xestospongia genus 25:861 Xestospongia sapra 15:312;17:33;28:677 Xestospongia sp. 5:350,353;18:718; 21:260,265,266;25:703,709,710,769, 859,898;26:487 (22R,23 R)-22,23-methylenecholesterol from 9:37 Ximeni caffra 22:535 Ximenia americana L. 22:535 for convulsions in children 22:535 Ximenia caffra 22:535 for epilepsy 22:535 Xiphidium 17:372 Xiphimena diversicaudatum 26:460 Xylocarpus grantum 7:190,191,195 Xylocarpus moluccensis 7:176,191,195 xylomollin from 7:185 Xylocarpus sp. 7:176 Xylopia aethiopica 20:484;21:611 oxoaporphines of 20:483 Xylopia aromatica 21:600 Xylopia longifolia 21:600 Xylotheca tettensis var. fissistyla 22:535 in convulsions 22:535
Yarrowia lipolytica (Candida lipolytica) 13:308,312,313
Yarrowinina lipolytica 25:150 Yersinia 4:195 Zahna africana 21:657 oleanane saponins from 21:657
Zalerion arboricola 22:69,248;23:343 Zamthaxylum americanum 9:402 Zanthoxyllum naranjillo 26:799 Zanthoxylum ailanthoides 10:152;21:378; 24:690;26:188;27:167
Zanthoxylum armatum 26:267 Zanthoxylum avicennae DC. 27:159
Zanthoxylum chalybaeum 22:535; 27:160;29:692
Zanthoxylum clavaherculis 24:686,689 Zanthoxylum conspersipunctatum 27:164 Zanthoxylum holtzianum 22:535 in convulsions 22:535
Zanthoxylum integrifolium 27:167 Zanthoxylum liebmannianum 26:450 Zanthoxylum nitidum DC. 27:159,160,168 6-oxoderivative of 27:160
Zanthoxylum punctatum 27:159 Zanthoxylum simulans 22:536;27:863 Zanthoxylum sp. 27:164 Zanthoxylum spinosum 27:170 Zanthoxylum tessmanii 27:159 Zanthoxylum usambarense 27:160 Zanthoxylum xanthoxyloides 21:611 Zea luxurians 29:600 Zea mays L. 19:247;23:342;25:671; 27:191,193,215 ;29:594,609
Zelus leucogrammus 2:299,301 Zephyranthes tiara 26:616 Zeuxis siquizorensis 18:724 Zingiber 17:365;26:905 Zingiber amaricans 24:274 Zingiber cassumunar 23:815,842 Zingiber officinale 9:321;17:365;23:845; 24:273,900,26:474,902 sesquiterpene from 8:52 Zingiber officinarum 17:378 Zingiber ottensi 22:536 for convulsions 22:536 Zingiber zerumbest 29:91 Zinnia elegans 25:377;27:765 Zinziber cassumar 17:365 Zinziber officinale 17:365 Ziziphusjujuba P. Miller 15:36,18:671; 21:674;27:42,47,48 jujuba saponin II from 27:41 jujuboside B from 27:41 ziziphin from 27:41 zizyphus saponin I-III from 27:42 Ziziphus mauritiana 20:507 Zizyphus 27:42,49 structures of 27:49 Zizyphus spinachristi 21:666 christinin A from 21:666 Zoanthus sp. 25:711;28:646 sphingolipid hariamide from
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28:646 zoanthid A from 28:646 Zonotrichia leucophyrys 5:837 hemoglobin components of 5:837 Zoobotryon verticillatum 17:85 Zoogloea ramigera 1:689,690 Zygomycota 22:246 ascomycetes from 22:246 Zygophyllum propinquum 9:59-62 saponins from 9:59-62 Zygosporiurn masonii 15:356 Zyzza fuliginosa 25:708,760,770 Zyzza rnassalis 25:760,898 Zyzzya cf. marasailis 25:790,824; 28:686;29:253 discorhabdin A from 28:686 makaluvamine F from 28:686 total synthesis of 28:686
