Studies in Natural Products Chemistry Volume 31 Indices (Part A)
Studies in Natural Products Chemistry edited by Atta-ur-Rahman
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Stereoselective Synthesis (Part A) Structure Elucidation (PartA) Stereoselective Synthesis (Part B) Stereoselective Synthesis (Part C) Structure Elucidation (Part B) Stereoselective Synthesis (Part D) Structure and Chemistry (PartA) Stereoselective Synthesis (Part E) Structure and Chemistry (Part B) Stereoselective Synthesis (Part F) Stereoselective Synthesis (Part G) Stereoselective Synthesis (Part H) Bioactive Natural Products (Part A) Stereoselective Synthesis (Part I) Structure and Chemistry (Part C) Stereoselective Synthesis (Part J) Structure and Chemistry (Part D) Stereoselective Synthesis (Part K) Structure and Chemistry (Part E) Structure and Chemistry (Part F) Bioactive Natural Products (Part B) Bioactive Natural Products (Part C) Bioactive Natural Products (Part D) Bioactive Natural Products (Part E) Bioactive Natural Products (Part F) Bioactive Natural Products (Part G) Bioactive Natural Products (Part H) Bioactive Natural Products (Part I) Bioactive Natural Products (Part J) Bioactive Natural Products (Part K) Indices (Part A)
Studies in Natural Products Chemistry Volume 31 Indices (Part A)
Edited by
Atta-ur-Rahman
H.E.J. Research Institute of Chemistry, University of Karachi, Karachi 75270, Pakistan
2005
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FOREWORD The present index volume comprises the contents of previous 30 volumes published in this series. I hope that it will allow the readers to readily extract the required information from any of these volumes. The volume comprises 4 separate indices, which are: ~
.
,
.
Cumulative General Subject Index Cumulative Organic Synthesis Index Cumulative Pharmacological Activity Index Cumulative Biological Source Index
This separation into different indices should also facilitate the readers in respect of obtaining the information required. I would like to express my thanks to Mr. Liaquat Raza and Ms Qurat-ul-Ain Fatima for their assistance in the preparation of the index. I am also grateful to Mr. Waseem Ahmad for the typing work and to Mr. Mahmood Alam for secretarial assistance.
Atta-ur-Rahman
Ph.D. (Cantab.), Sc.D. (Cantab.) Director, H.E.J. Research Institute of Chemistry, Chairman (Federal Minister), Higher Education Commission
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oo
VII
CONTENTS
Foreword
V
Cumulative General Subject Index Cumulative Organic Synthesis Index
871
Cumulative Pharmacological Activity Index
1007
Cumulative Biological Source Index
1225
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Indices
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CUMULATIVE GENERAL SUBJECT INDEX VOLUMES 1-30
AI adenosine agonists 25:265 somatostain as 25:265 opiates as 25:265 A1 and AzA-adenosine 25:895 A2-agonists 25:265 A-549 (human lung adenocarcinoma) 30:588 activity of (-)-deoxypodophyllotoxin against 30:588 activity of (-)-yatein against 30:588 1AA oxidation 25:657 inhibitor of 25:657 AADC 30:380 activity of 30:380 deficiency of 30:380 in abnormal sleeping 30:380 in eye movement abnormalities 30:380 in feeding difficulties with esophagea reflux 30:380 C-Aalkylation 10:412 AAPM [(2,2'-azobis (2-amidino propane) dihydrochloride)] 26:763 Aargesin 26:241 Aaronsohnia sp. 29:683 AB-1006 A9 21:411 ABA 27:341,354 of l'-methyl ether 27:341 photoisomerization of 27:354 [3',5,7-2H6] ABA 27:353 Abamectin (avermectin B) 12:9 ABC-transporter family 21:158 Abdominal constriction test 30:207 activity of (-)-menthol in 30:207 Abdominal pain 30:203,205 use of ginseng root in 30:203 use of Psycotria colorata in 30:205 1 l(15~l)Abeataxan 20:80,100,101 (3~20)Abeataxan 20:80,106 25-(10~9)Abeo-26(8~ 15) abeo913,1413,15Gt-olean-5-ene-313,29-diol 5:744,748,750
19(4-->3)-Abeo-8 ct, 13(S)-epoxylabda4(18), 14-diene 29:102 activity in EBV bioassay system 29:102 9( 10--~19)Abeo-diene steroidal alkaloids 2:205,206 Abernaemontana penduliflora 28:234 Aberrant crypt foci (ACF) 25:65 Abies amabnilis 22:391 Abies balsamea 22:384 from balsam 22:384 Abies grandis 22:391 Abies koreana 20:619 Abies mariestii 20:619 Abies marocana 29:99 Abiesen 20:283 Abiesenonic acid 25:60 methyl ester 25:60 19-nor-Abieta-4(18),8,11,13-tetraen-7one 29:100 activity in EBV assay system 29:100 Ent-Abieta-8(14), 13(15)-dien- 16,12olide (jolkiolide E) 9:283,284,290 Abieta-8,11,13-trien-7-one 29:99 activity in EBV assay system 29:99 18-nor-Abieta-8,11,13-triene-4c~,7c~, 15triol 29:99 activity in EBV assay system 29:99 Abieta-8,11,13-triene-7cz, 15,18-triol 29:99 activity in EBV assay system 29:99 Abieta-8,11,13-triene-7c~,l 5,18-triol 7acetate 29:99 activity in EBV assay system 29:99 Abietane 9:297 Abietane diterpenoids 20:660-680; 23:682 Abietatriene 2:402,403
Abietatriene-6-one 14:669,670,673, 674,676 Abietic acid 29:99,188 activity in TPA assay system 29:99 activity in CRG assay system 29:99 pisiferic acid synthesis from 29:188 Abiotic stress 23:741 Abisapogenol 25:95 Abnormal Beckmann rearrangement 16:133 4-AboA 27:193,203,204,225 formation of 27:204 Abramov reaction 6:353 Abri Herba 25:99 antihepatotoxic effect of Ogs from 25:99 Abrisapogenol A 25:96 Abrisapogenol B 25:96 Abrisapogenol C 25:96 Abrisapogenol D 25:96 Abrisapogenol F 25:97 Abrisapogenol I 25:97 Abrisapogenol L 25:96 Abrisaponin 25:97 Abrisaponin A 25:96 Abrisaponin C 25:96 Abrisaponin D2 25:96 Abrisaponin D3 25:96 Abrisaponin D~ 25:96 Abrisaponin I 25:97 Abrisaponin L 25:96 Abrisaponin SB 25:95 Abrisaponin SO~ 25:95 Abrus contaniensis 25:93 Abrus fruticulosus 15:26;27:15 abrusoside A from 27:15 abrusoside B from 27:15 abrusoside C from 27:15 abrusoside D from 27:15 Abrus precatorius 7:152,15:25; 21:674 ;22:510;25:93 ;27:15,27 abrusoside A from 27:15,27 abrusoside B from 27:15,27 abrusoside C from 27:15,27 abrusoside D from 27:15,27 abrusoside E from 27:15,27
cycloartane from 21:674 for epilepsy 22:510 Abrus sp. 25:180 Abrusgenic acid 7:152 Abrusoside A 27:15,27,28 structure of 27:28 Abrusoside B 27:15,27,28 structure of 27:28 Abrusoside C 27:15,27,28 structure of 27:28 Abrusoside D 27:15,27,28 structure of 27:28 Abrusoside E 27:15,27,28 structure of 27:28 Abscisic acid 25:367;27:330,331,322, 335,337,352,388 activity of 27:331 biological activity of 27:332 conformations of 27:335 IH-NMR spectra of 27:339 metabolic inactivation of 27:322 NOE experiment of 27:338 structure of 27:321 utility of 27:331 (-)-Abscisic acid 27:346 formation of 27:346 (+)-Abscisic acid 27:346 formation of 27:346 Abscisic acid analogs 27:321,323-329 activity of 27:483 Abscisic acid ring 27:336,338 interconversion of 27:336 Abscisic acid-GE 27:354 hydrolysis of 27:354 Abscisic aldehyde 27:321 in biosynthesis 27:321 Absidia sp. 25:160 Absinthin (guaine sesquiterpene dimer) 29:574 effects on HIV- 1 protease 29:574 Absintholide (guaine sesquiterpene dimer) 29:574 effects on HIV-1 protease 29:574 Absolute configuration 9:27 by CD procedure 9:27 by Horeau procedure 9:25,26 by Nakanishi's method 2:89
in 24-(13-hydorxyethyl)-in 24(carboxy-methyl) steroids 15:79-81 in 24-ethyl-26-hydroxysteroids 15:84 in 24-hydroxymethyl steroids 15:79 in 24-hydroxysteroids 15:76,77 in 24-methyl-25,26-dihydroxysteroids 15:84-86 in 24-methyl-26-hydroxy and 24-methyl-26-oic steroidal sidechains 15:81-84 in 26-hydroxysteroids 15:77,78 of (+)-aristoserratine 11:296 of (+)-monomoriwei 6:449,450 of (-)-hobartine 11:290 of (-)-peduncularine 11:284 of 3c~,13-dihydroxy- 11epiapotrichothecenes 13:520 of amphotericin B 6:231 ofaureol 9:31 ofbenzo [a] pyrene oxide 7:8,14 ofcarotenoids 7:321 of decaprenoxanthin 7:355 of liverwort sesquiterpenoids 18:607-646 of Mosher's esters 13:77 of penems 4:435 ofphoracantholide I,J 6:546 of quinocarcin 10:126 of R, S-4-hydroxycyclopentenones 6:315 of sclerosporin 6:549-551 of sigmosceptrellins A-C 9:16 of solenopsin B 6:430 of sugars saponins 15:190 of taxol 11:3,7 of thienamycin 4:433,436 of urdamycin A 11:134 Absolute stereostructure 28:11 ofbroussonetine C 28:11 ofbroussonetine L 28:12 AB TS (2,2'-azino-bis-( 3-ethylthiazoline6-sulfonic acid) 26:1014,1015,1020 oxidation of 26:1016 Abyssinian tea 23:653 (2S)-Abyssinone II 28:17 as aromatase inhibitor 28:17
Acacetin (5,7-dihydroxy-4'-methoxyflavone) 29:571 inhibition of HIV- 1 protease 29:571 Acacia astringens 7:427 Acacia auriculiformis 21:674;23:487, 498;26:467 triterpenoid saponin from 21:674 Acacia catechu 29:678,680 Acacia confusa 29:603 Acacia honey 28:386 aroma of 28:386 Acacia melanoxylon 27:838 Acacia nilotica 7:427;26:358 Acacia spp. 29:582 Acacia tomentosa 7:427 Acaciamine 23:498 Acaciaside A 21:674;23:497 Acaciaside AB 26:467 Acaciaside B 21:674;23:497 Acaciaside C 23:497 Acalycigorigia inermis 5:370 Acalycigorigia sp. 5:368,369 Acalyphafruticosa sk. 22:510 for epilepsy 22:510 Acalyphafruticosa Forsk. 22:510 for epilepsy 22:510 Acanthacerebroside A 18:481 Acanthaster planci 7:288 acanthaglycosides A-D,F from 7:288 marthasteroside A from 7:288 thomasteroside A from 7:288 Acanthella acuta 21:329;25:848, 852,853 Acanthella aurantica 21:270 Acanthella cavernosa 21:351,353,355, 356,359,361,365-367 ;25:689,858; 26:465;28:663 10-epi-isokalihinol H from 28:663 15-isothiocyanato- 1-epikalihinene from 28:663 Acanthella klethra 20:525;25:848, 852;26:810;28:662 isothiocyanates from 28:662 Acanthella pukherrina 25:853;28:660 isothiocyanates from 28:660 sesquiterpenes from 28:660
Acanthella pulcherrima 25:852 Acanthella sp. 21:334;25:852,853; 28:663 kalihinol G of 28:663 kalihinol H of 28:663 Acanthenes A-C 21:334 Acanthicifoline 7:191 Acanthifolicin 5:384;28:710;25:832 episulfide group of 28:710 Acanthodendrilla sp. 25:704;28:702 acanthosterol sulfate A of 28:702 acanthosterol sulfate B of 28:702 acanthosterol sulfate C of 28:702 acanthosterol sulfate D of 28:702 acanthosterol sulfate F of 28:702 acanthosterol sulfate G of 28:702 acanthosterol sulfate H of 28:702 acanthosterol sulfate I of 28:702 acanthosterol sulfate J of 28:702 antifungal activity of 28:702 A canthodris nanaimoensis 19:139 Acanthoic acid 29:103 activity in TNFc~ bioassay system 29:103 Acantholippia seriphioides 21:618 Acanthomyops claviger 6:454 Acanthopanax koreanum 29:103 Acanthophyllum gypsophiloides 26:3 Acanthophyllum squarrosum 24:149; 26:31,50,55 squarroside A from 26:31 Acanthophyllum squarrosum 26:55 immunomodulatory effect of 26:55 Acanthoscelides obtectus 10:160 Acanthosterol sulfate A-J 25:704 Acanthus ebracteatus 7:176 Acanthus illicifolius 7:176,179,181,182, 189-191,193 Acanthus mollis 27:188,191 Acarapis woodi 28:387,390 in honey bees' tracheal tubes 28:387 infestations in Minnesota 28:390 Acarbose 13:3 as or-amylase inhibitor 13:3 as ot-glucosidase inhibitors 7:47 as antihyperglycemic drug
10:505 as antihyperlipoproteinaemic drug 10:505 Acaria saxatilis 22:634 Acaricidal activities 24:799;28:403,406, 412,422 against Dermatophagoides pteronyssinus 28:422 against Psoroptes cuniculi 28:412 against Rhipicephalus appendiculatus 28:406 for killing adult ticks 28:403 of caffeine 28:422 ofCuminum cyminum 28:427 of essential oils 28:412,427 of Eucalyptus camaldulensis 28:427 of eugenol 28:403 of extract prepared by microwave assisted process (MAP) 28:427 of Lavandula angustifolia 28:412 oflinalool 28:412 of Margaritaria discoidea 28:406 of Origanum syriacum var. bevanii 28:427 of phenylpropanoid derivatives 28:403 of Pimenta dioica 28:403 ofPimpinella anisum 28:427 of Tanacetum vulgare extracts 28:427 of 13-thujone 28:427 Acaricidal properties 28:400,406 of benzaldehyde 28:406 of carvacrol 28:406 of cedrene 28:406 of c~-cyclocitral 28:406 of [3-cyclocitral 28:406 of Euphorbia obovalifolia latex 28:400 of Ficus brachypoda latex 28:400 of geraniol 28:406 of (E)-geranylacetone 28:406 of c~-ionone 28:406
of linalool 28:406 of m-cymene 28:406 of methyl salicylate 28:406 of nerol 28:406 of nerolidol 28:406 of nonanal 28:406 of 13-ocimene 28:406 ofphenylacetaldehyde 28:406 of phenylacetonitrile 28:406 of c~-terpineol 28:406 Acaricide 28:381,429,435 cross-resistance of 28:429 Acarnus bergquistae 25:724 Acarus siro 28:382,423 as mite sp. 28:382 Acarviosin 22:177 Acarviosine 10:503,504,506 Accedine 5:125 Accedinine 5:125 Accedinisine 5:125 Acer nikoense 26:889,895,899 Acer saccharumn 25:666 Acer sp. 21:502;26:905 Acernicoense 17:358,367-368,375 Acerogenin A 17:367,375;20:276 Acerogenin A-L 26:899 Acerogenine-E 17:368 Acerolide 23:175 Aceroside I 17:367 Aceroside IV 17:367 Aceroside V 17:367 Aceroside VII 17:358 Aceroside XI 17:368;26:895 Acerosterol 23:177 Acesulfame-K 15:4 Acetal 6:336 Acetaldehyde dependent aldolase (DERA) 30:428 Acetalization 1:584 trans-Acetalization 4:325,326,331, 338,339,495 6-Acetamido-2,3,4-tri-O-allyl-6-deoxya-glucoheptopyranosiduronic acid 11:434,435 2-Acetamido-2-deoxy-D-glucopyranose 6:351 2-Acetamido-2-deoxy-D-glucopyranosides 6:389
2-Acetamido-2-deoxyglucomannans 5:286,287 5-Acetamido-3,5-dideoxy-D-glycero-Dgalacto-2-nonulosonic acid 30:420 2-Acetamidofluorene 26:1003 p-Acetamidophenyl- 1,4,4'-dithiocellotrioside 8:351 p-Acetamidophenyl- 1,4-dithiocellobioside 8:350,351 14-Acetamidosantonin 24:124,125 Acetaminophen 26:257;30:192 as analgesic/antipyretic 30:192 Acetaminophenone 25:219,614 Acetate/mevalonate pathway 25:130 Acetobacter suboxydans 17:636-637 Acetobromoglucose 10:366,367 [3-Acetochloromannose 8:321,322 Acetogenic cyclic peroxides 9:18 Acetogenins 9:385,391,392,395,397399,403;18:193-227;19:81 Acetolysis 30:489 (-)-Acetomycin 10:443 antimicrobial activity of 10:443 antitumor activity of 10:444,447 (+)-5-epi-Acetomycin 10:447 antitumor activity of 10:447 Acetonide 14:160;19:489 Acetonitrile 22:205 Acetonylbutanolides 17:273 Acetophenone 2:169,170;25:666 Acetophenone phenylhydroazone 9:581 3-Acetoxy monomethyl phthalates 14:5 19-Acetoxy- 11-methoxytabersonine 2:375 3 [3-Acetoxy-11-ursen- 13~,30-olide 654,656 IR spectrum of 30:654 NMR spectroscopic data of 30:654 structure of 30:656 16-Acetoxy- 12-O-acetyl-horminone 15:169,170,173 2c~-Acetoxy- 14-hydroxy- 15-iso-valeroyloxy-9-oxo-costunolide 29:89 activity in NFkB assay system 29:89 activity in TNFc~ assay system 29:89
( 15R)- 15-Acetoxy- 15,20-dihydrocatharanthine 14:815 20-Acetoxy- 15,20-dihydrocatharanthine 4:32 (15'S)- 15'-(Acetoxy-20'-deoxyvinblastine 14:815,816 from (15R)-I 5-acetoxy-15,20dihydro catharanthine 14:815,816 1ot-Acetoxy-20Ctv-hydroxy-24tx,25c~epoxywitha-5-ene-22,26-olide-413-0glucopyranoside 20:191 22-Acetoxy-23,24-dinorchola- 1,4,6trien-3-one 11:398 (+)- 1-Acetoxy-2-epipinoresinol 5:538-540 1ct-Acetoxy-2ct,6[3,9[3-trifuroyloxy-4[3hydroxy-dihydro-[3-agarofuran 29:87 4-Acetoxy-3 [ 1'-tert-butyldimethylsilyloxy) ethyl]-2-azetidinone 4:448 20S-Acetoxy-3 [3-16-dihydroxylanost-7en-18-oic acid-18,16-1actone 7:~269 3-Acetoxy-4-hydroxybenzaldehyde 8:166,167 9ot-Acetoxy-4 [3,15-epoxymiller- 1( 10)-Zenolide 29:89 activity in NFkB assay system 29:89 2R, 3R-(+)-3-Acetoxy-5,7,4'-trihydroxyflavanone 27:34,35 structure of 27:35 Ac etoxy-5,7- dihydroxy-4 '- metho xy flavanone 27:34,35 structure of 27:35 (+)- 1-Acetoxy- 6- epipinoresinol 5:538-540
8ot-Acetoxy-6-epi-tannunolide A 27:583 1-Acetoxy-6cx-hydroxy-germacran1(10), 3(4)-dien-8,12-olide 27:561 16-Acetoxy-7,8-epoxy-3,12dolabelladien-13-one 20:491 2-Acetoxy-8,13-dihydroxy- 11-epi APO 13:522 12-Acetoxy-8,13-dihydroxy- 11-epiapotrichothec-9-ene 9:20
7fl-Acetoxy-8,13-epoxy- 1a,6/3,9 atrihydroxylabd- 14-en-11-one 25:256 1[3-Acetoxy- 8 [3-hydroxyeudesm-4(15), 7-diene-8-12-olide 20:660 3 [3-Ac etoxy- 8 [3-i sobutyrylo xy-re ynos in 29:87 activity in Mam-2 assay system 29:87 activity in DIF assay system 29:87 15-Acetoxy-9ct-hydroxy-8 [3-methacryloyloxy- 14-oxo-acanthospermolide 29:89 activity in NFkB assay system 29:89 15-Acetoxy-9cz-methacryloyloxy-8 f3hydroxy- 14-oxo-acantho-spermolide 29:89 activity in NFkB assay system 29:89 5-Acetoxyarctigenin monoacetate 18:601 6'-Acetoxyavarol 15:301 1-Acetoxybutadiene 1:571 l'-Acetoxychavicol acetate 23:800 25-Acetoxycholesta- 1,4,6-trien-3-one 11:385 2tx-Acetoxycholestanone 18:888 2[3-Acetoxycholestanone 18:888 3-Acetoxycostunolide 29:89 activity in NFkB assay system 29:89 (+)-Acetoxycrenulide 18:22-28 15-Acetoxy-eremantholideB 29:89 activity in NFkB assay system 29:89 activity in TNFet assay system 29:89 l'-Acetoxyeugenol 23:800 12-Acetoxyfamesol acetate 27:586 3-Acetoxyflavanones 30:729 structure of 30:729 tx-Acetoxyfuranone 12:14 3-Acetoxyguaiazulene 14:321 23S-Acetoxyholost-7-en-3 [3-ol 7:273 613-Acetoxyho lo sta-7,24-dien- 3 [3-ol 7:275
23S-Ace to x yho losta- 7,25 -dien- 313-o1 7:273 16otAcetoxy-holosta-7-en-3b-ol 7:2771-Acetoxyisocomene 3:6,60 6-Acetoxyldihydrochelerythrine 27:168 313-Acetoxymalabarican- 14(26), 17E,21 triene 27:591 ent- 13-epi- 12a-Acetoxymanoyl oxide 25:273 10-Acetoxymenthol 25:160 6-Acetoxymethyl-2,6-dimethyl-9methoxy tricyclo [5.3.01'5] undec-9en-8,11-dione 8:163 5-Acetoxymethyltrachelogenin 18:602 5-Acetoxymethyltrachelogenin monoacetate 18:602 9a-Acetoxy-miller- 1(10)-Z-enolide 29:89 activity in NFkB assay system 29:89 13-Acetoxymodhephene 3:6,61 18-Acetoxy-Na-deacetylisoretuline 1:38-39 18-Acetoxynorfluorocurarine 1:38-39 (+)- 1-AcetoxypinoresinoI-[3-D-glu 26:200 (+)- 1-Acetoxypinoresinol 5:523,533, 538,544;26:200 (+)-Acetoxypinoresinol dimethyl ether 26:241 as PAF-induced inhibitor 26:241 (+)- 1-Acetoxypinoresinol-4"-O-methyl ether 5:523,533-535 (+)- 1-Acetoxypinoresinol-4"-O-methyl ether-4'-[3-D-glucoside 5:523 (+)- 1-Acetoxypinoresinol-4'- 13-Dglucoside 5:523 6[~-Acetoxy-pseudotropanol 21:751 3-Acetoxypyrrol-2(5H] -one 13:117, 118 (+)- 16c~-Acetoxytabersonine 2:186 8cc-Acetoxy-tannunolide E 27:585 5-Acetoxytrachelogenin diacetate 18:601 6[3-Acetoxy-tropanone 21:751 6ot-Acetoxyvouacapan- 17,7 [3-1actone 29:103
activity in AOS bioassay system 29:103 13-Acetoxy-cx-diazoesters 30:447 reaction of 30:447 15-Acetylcardiopetamine 26:869 N-Acetyl cysteamine 13:496 Acetyl pyrazine 13:320 ~-Acetyl alcohol 14:462 Acetyl CoA carboxylase 25:525 3-Acetyl deoxynivalenol 13:520,521, 536 N-Acetyl glucosamine 7:31,47,49 ~3-(1-3)-N-Acetyl glucosaminyltransferase 10:484 N-Acetyl isomuramic acid 6:386,387 O-Acetyl isophotosantonic lactone 14:357 Acetyl kaikasaponin 25:95 N-Acetyl muramic acid 7:31,47,49 N-Acetyl neuraminic acid (NANA) 13:207-210 O-Acetyl normacusine B 13:386 O-Acetyl preperakine 13:387 O-Acetyl villamine 13:396 2-O-Acetyl-(S)-(+)mandelic acid 13:468,469 Na-Acetyl- 11,12-dihydroxyaspidospermatiine 1:40 Na-Acetyl- 11-hydroxyaspidospermatidine 1:40 Acetyl-11-keto-13-boswellic acid (triterpene) 29:585 effects on LELA 29:585 6-O-Acetyl-2,3,4-tri-O-benzyl-Dglucono- 1,5-1actone 12:335 3-Acetyl-2,6-dimethylpyridin-4-one 13:545 7'-Acetyl-2-methoxypicropodophyllin 30:586 2-Acetyl-3,5-dihydroxy- 1-geranoxy-6methyl-4-(2-methyl)butyryl-benzene 30:615 structure of 30:615 3-Acetyl-4,6-dimethylpyridin-2-one 13:545 1-O-Acetyl-4-methoxylycorine 26:100, 615
10
acetylation of secologanin 26:100,615 (7R, 8S,7 'R,8' R)-(+)-7 '-Ac etyl- 5 'methoxypicropodophyllin 30:586 ~3CNMR comparison of 30:586 circular dichroism (CD) spectrum of 30:586 ~H NMR comparison of 30:586 HREIMS of 30:586 molecular formula of 30:586 ROESY correlation of 30:586 ROESY NMR of 30:586 stereochemistry of 30:586 4-Acetyl-6,8-dihydroxy-5-methyl-3,4dihydroisocoumarin 15:409 17-O-Acetylajmaline 9:183-185 Acetylamino- 1,2-dihydroacronycine 20:800 2-Acetylamino-3H-phenoxazin-3-one 27:219 structure of 27:219 5-Acetylamino-6- formyl amino-3methyluracil 22:5 Acetylaminonaphthoquinone 9:437 Acetylandromedol 20:27 Acetylannulatophenonoside 30:624 N,,-Acetylaspidospermatidine 1:40 Acetylastrogaloside I 25:193 3-Acetylated flavanones 798 Acetylation 19:480 ofsyn alcohol 19:480 [3-Acetylation procedure 10:447 for acetomycin synthesis 10:447 stereoselective 10:447 Acetylation reaction 23:172 oftobagolide 23:172 2-Acetylbutyrolactone 8:284,285 Acetylcholine 22:15,29;25:516,519, 520,527,530,547 nicotinic receptor for 25:519 vasodilator effect of 25:595 Acetylcholine esterase 22:16 Acetylcholine receptor 18:863 Acetylcholine-gated Na+/K+channels 25:527 Acetylcholinesterase 7:18 Acetylcholinesterase inhibitors 21:585 Acetyl-coenzyme A 7:112
(+)-N-Acetylcolchinol 29:376 allocolchicinoids total synthesis of 29:376 19-Acetylcorrin 9:600,601 3-Acetylcoumarins 368 2-O-Acetyl-D-glucal tetraacetate 10:414 (+)-Acetyldomesticine 16:519 Acetylenation 1:611,612 of acetals diastereoselective 1:611,612 Acetylene-C-glycosides 10:359 Acetylenes 23:341 ct,[~-Acetylenic alcohols 4:493 Acetylenic compounds 30:706 C-Acetylenic hexopyranose 10:374 Acetylenic oxy-Cope rearrangement 8:250 3-O-Acetylerythrodiol 25:59 2'-Acetylglaucarubinone 7:379,380 N-Acetylglucosamine 1:417 Acetylglucosamine 30:95 molecular weight of 30:95 [3-N-Acetyl-glucosaminidases 12:346 [3-(1-6)-N-Acetylglucosaminyltransferase 10:486 in biosynthesis of I-antigens 10:486 3-Acetylgoniotriol 9:394 (+)- 8-Acetylgonoiotril 19:463 8-Acetylharpagide 29:83 activity in EBV, liver-l, lung-2, skin-1, skin-4 assay systems 29:83 Acetyl-histamines 15:328 Acetyl-horminone 20:670 N-Acetylisocodonocarpine 9:73-75,77 O-Acetyl-isopseudolycorine 26:614 O-Acetylisoretuline 1:38,39 N-Acetyllactosamine (2-acetamido-2deoxy-4-O-[3-D-galactopyranosyl-c~D-glucose) 10:459,461-467 3-Acetylleptophylline-A 20:486,487 1-O-Acetyllycorine 26:615 Acetylmelodorenol 9:400,152 N-Acetyl-muramyl-(L)-alanyl-(D)isoglutamine(MPD) 13:210-212
11 N-Acetyl-muramyl-L-alanyl-D-isoglutaminyl -S-tert-butyl-c ysteamine 18:927 Nb-Acetyl-Nb-methyltryptamine 9:178 7-Acetylneotrichilenone 9:297 Acetylneuraminate pyruvate lyase 11:466,467 N-Acetylneuraminic acid 10:550; 30:420,425 synthesis of 30:425 5-N-Acetylneuraminic acid 27:104 3-19-Acetyloleanane 25:59 Acetyloleanolic acid 25:59 Na-Acetyl-O-methyl strechnosplendine 9:188 (+)-Acetylphomalactone 19:479 antifungal activity of 19:479 antitumor activity of 19:479 insect antifeedant activity of 19:479 plant growth inhibitory effect of 19:479 (7R,8S,7'R,8 'R)-(+)-7'-Acetylpicropodophyllin 30:568,593 use of soft agar transformation assay 30:593 Acetylpipitzol 5:778 O-Acetylpolyneuridine 5:128 4~-O-Acetyl-pseudoguain-6~-olide 29:90 activity in TPA assay system 29:90 3-Acetyl-pyrrolidine-2,4-diones 14:100 O-Acetylretuline 1:38,39 Acetylsalicylic acid 26:162;30:192 from willow-derived salicylic acid 30:192 synthetic derivatives of 26:162 O-Acetylsolasodine 20:489;22:28 N-Acetylsolasodine 20:490 Acetylsoyasaponin 25:95 Acetylstrychnovoline 6:523,524 3-Acetylteumicropin 23:617 13C-NMR data of 23:617 IH-NMR data of 23:617 (+)-Acetylthaliporphine 16:519 2-Acetylthiazole (2-ATT) 11:443,444 Acetyltrimethylammonium bromide 27:509
O-Acetylvallesamine 9:167,168,171 Acetylvismione D 7:418-420,424 3-Acetyl- [3-D-digitoxose 15:362 N-Acetyl-[3-D-hexosainidase 7:416,417 3-Acetyl-[3-1actam 12:152,161 Ach receptor 21:92,98 Achantaster planci 15:45 AChE activity 21:748 AChE inhibitor 21:749 Acheta domesticus 22:387;29:6 Achillea arten 21:378 tetradecadienoylpyrrolidine from 21:378 Achillea millefolium 10:151;21:378; 24:686,688-690 Achillea nana 10:151;21:378 Achillea nobelikii 24:687-689 Achillea pannonica 29:88 Achillea ptormica 24:691 Achillea setacea 29:89 Achillea sp. 24:684,687;29:683 Achillea sudetica 24:687 Achillin 7:234 Achiral heptanal 12:55 Achyranthes aspera L. 22:510 for hysteria 22:510 Achyranthes fauriei 29:10 Achyrocline flaccida 22:347 7,4-dihydroxy-5-methoxy flavone from 22:347 Achyrocline satureioides 22:346 as antispasmodic 22:346 as choleretic 22:346 as hepatoprotective 22:346 quercetin from 22:346 Acicerone 27:498 Aciclovir (9-[2-hydroxyethoxy methyl] guanine) 10:585 antiviral activity of 10:585 Aciculites orientalis 26:1214 Aciculites sp. 26:1175 Aciculitins A-C 26:1214 Acid-catalysed aldol condensation 30:217 of phenylacetone 30:217 Acid-catalysed cyclization 30:217 of 1-benzyl- 1,2,3,4-tetrahydro isoquinolines 30:217
12 Acid-catalysed methanolysis 30:44 Acid-catalysed rearrangement 6:115; 23:487,515 of aglycones 23:487,515 of (+)-endo-3-bromocamphore 16:147 of spiro cyclic lactone 16:225 Acid-induced abdominal contraction test 30:205 activity of (+)-allomatrine in 30:205 activity of (+)-matrine in 30:205 Acid-labile protecting groups 30:441 Acifluorfen 25:669 Acilius sulcatus 5:700 Acinetobacter calcoaceticus 12:103; 27:218 Acinos suaveolens 30:276 apigenin from 30:276 Acinosolic acids A,B 7:144,145 Aclacinomycine A 4:317,318 Acnistus arborescens 20:247 Acnistus breviflorus 20:234 Acomycota 22:246 basidiomycetes from 22:246 Aconin 20:22 Aconite 24:898-899 neuromuscular blocking effect of 24:898-899 trans-Aconitic acid 26:793,794 Aconitine 20:22;21:98,109;22:17; 24:898-900;26:868,869,870,871 as anti-inflammatory agent 24:898 as cardiotonic agent 24:898 for relieving muscle pain 24:898 Aconitum 26:868 Aconitumjaponicum. 22:510 for convulsions 22:510 Aconitum napellus 20:19 [3-Acoradiene 15:261,262 ot-Acoradiene 15:262 Acoradienes 5:734 c~-Acorene 15:260 (-)-Acorenone 16:222 Acorenone B 21:231 Acorospora gobiensis 25:802
Acorus calamus L. 21:595;22:510; 28:401 in hysteria, convulsions and epilepsy 22:510 Acorus caninum 26:471 Acorus graminous 26:362,470 Acosmium panamense 27:269 (cis-ACPC) 22:273,275 Acquired immunodeficiency syndrome (AIDS) 23:3;25:734,941,948;30:412 Acrasiomycetes 9:220 Acremonium sp. 27:805 Acridine 25:542 based PKA inhibitor 25:542 Acridone alkaloids 13:347-382 Acrolein 21:308 Acromelic acid 21:70 Acronychia baueri 13:347,349;20:789 Acronychia oigophylebeia 13:348,350 oligophylidine from 13:348,350 Acronycine 13:365-375 antitumor activity of 13:365-375 Acronycine azine 20:791 Acronym SNAP 21:16 Acroscyphus sphaerophoides 5:310 Acrostalagmus genus 21:221 ;28:454 Acrostalamus fungi 28:455 acrostalidic acid from 28:455 acrostalic acid from 28:455 isoacrostalidic acid from 28:455 Acrylamide reagents 4:45,18:320 Acrylonitrile 14:551 Acrylonitrile reagents 18:318 Ac-SAMM 2 23:29,37 ~3C-NMR assignments of 23:31 IH-NMR assignments of 23:29 structure elucidation of 23:37 ACT1-VII 22:265 Actaea 25:180 Actamycin 9:248,250 Acteoside 5:507;25:468,543 (ACTH) 25:265 [3-Actin 30:779 cytokine mRNA expression of 30:779 Actinase E 25:438 Actinidia deliciosa 26:1145,1158 Actinidia polygama Miq. 16:290,291 Actinobacter calcoaceticus 30:421
13 (+)-Actinobolin 16:3 antineoplastic activity of 16:3 as microbial antitumor antibiotics 16:3 dental cariostatic activity of 16:3 immunosuppressive activity of 16:3 Actinocin 26:1009 Actinodaphne lancifolia 28:419 Actinoerythrol 30:526 structure of 30:526 Actinogyra muelenbergii 5:311-313 Actinomadura 26:451 Actinomadura hibisca 23:343 Actinomadura melliaura 12:366,368 AT 2433-A1 and A2 from 12:366, 368 AT 2433-Bland B2from 12:366, 368 Actinomadura sp. SF-2370 5:55;12:366 K-252a (SF-2370) from 368 Actinomadura spiralis 25:776 Actinomyces naeslundii 21:607 Actinomyces viscosus 21:613;23:536 Actinomycetales 19:559 Actinomycete strain (LIA-0788) 21:414 altamycin A from 21:414 Actinomycetes 21:186,263,265;22:80; 29:230 Actinomycin 26:1009 Actinomycin D 21:608;24:547;25:58, 461,479;26:1009 antiviral microbial-derived compound 24:547 Actinomycin synthetase I, II and III 26:1010 Actinoplanes coloradoensis 17:283 Actinoplanes sp. 25:777;28:147 effect on K-cells-IL2-activated killer cells 25:273 K-cells-IL2-activated killer cells 25:273 Actinoplanic acids 24:428-429 activity against VSV, HSV-1, poliovirus SV, FMDV 24:524 structure of 24:428,429 Actinopyga agassizi 7:267,269;21:315 holothurins from 7:267,269
Actinopyga echinites 7:269 echinoside A&B from 7:269 Actinopyga mauritiana 7:281 Actinorhodin 22:265 Actinostemma lobatum 21:634 Action potential 21:8 Activators 27:833 from Daphne cannabina 27:833 from Daphne mezereum 27:833 from Thymelaceous plants 27:833 from Wikstroemia indica 27:833 5-Active peptide analogues 30:801 synthesis of 30:801 Activities 22:354;25:257;27:323,331, 333,504,513 for Astragalus spp. 27:483 from Phyllanthus amarus 27:840 of Astragali radix 27:513 of abscisic acid 27:331,352 of abscisic acid analogs 27:323-329 of diarylheptanoids 27:852 of enzymes 27:378 of flavonoids 27:504 of fluorinated probes 27:333 ofhydrolysable tannins 27:840 of labdane 25:257 of monoterpenes 27:384 ofodour substances 27:378 ofphosphorylase kinase 27:852 of protein kinases 27:826 of serine 27:850 of threonine 27:850 of tyrosine 27:850 of xanthine oxidase 22:354 activity in AOS bioassay system 29:103 activity in DIF assay system 29:90 activity of 17:378;25:257 activity against A549 (human lung adenocarcinoma) 30:588 activity against HT-29 (human colon carcinoma) 30:588 activity against KB-16 (human oral epidermal carcinoma) 30:588 activity against P-388 (murine
14 lymphocytic leukemia) 30:588 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:589 platelet aggregation inhibitor 30:594 macrolide as 17:16 sesquiterpene dialdehydes 17:233 epothiolones as 24:406 Actomysin ATPase-activating activity 23:193 of penaresidin A 23:193 ofpenaresidin B 23:193 Aculeanic acid 23:343 Acuminatin 26:199 Acuminatopyrone 13:544,545 Acumycin 5:613 Acute diarrhoeal disease 30:747 Acute gastritis 30:153 Helicobacter pylori as causative agent of 30:153 Acute hepatitis 30:406 chemotherapy of 30:406 Acute leukemia 14:805 in children 14:805 vinblastine for 14:805 vincristine for 14:805 Acute myocardial infarction (AMI) 30:839,844 use of fibrinolytic agent 30:839 Acute pain 30:799 analgesic alkaloid in 30:799 Acute phase proteins 25:461 Acute rheumatism 26:398,400 Acute toxicity 27:307 of stevioside 27:307 of steviol 27:307 Acyclic 11-carboxy- 12-nor-transnerolidol 29:87 activity in EBV assay system 29:87 Acyclic cis-nerolidol 29:87 activity in EBV assay system 29:87
Acyclic trans-nerolidol 29:87 activity in EBV assay system 29:87 Acyclovir 21:694,698;24:474,486; 25:116;26:226 as anti-viral agent 24:474,486 Acyl carrier protein (ACP) 22:265; 25:501,509 Acyl group 23:403 in oligomers 23:403 3-Acyl tetramic acid 28:111,112,114 tautomeric forms of 28:112 Adenichrome 28:647 Fe(III)-containing pigment as 28:647 11c~-Acyl turkesterone 29:19 as synthetic ecdysteroid analogues 29:19 6ot-Acylamino radical 12:44 Acylase group 6:551 Acylated amidines 5:574 Acylated carotenoid glucosides 30:523 salimixanthin 30:523 thermozeaxanthin 30:523 Acylated flavonol-glycosides 17:142 Acylated guanidines 5:574 Acylated polyhydroxy-oleanene-3-Omonodesmosides 21:675 N-Acylated tetramic acid 21:415 N-Acylation 16:22 with Cbz-L-alanine 16:22 Acylation 30:627 of hexaenal 6:264,267 selective 6:283,284 with N,N-diisopropylcarbamoyl chloride 10:15 intramolecular 16:18 with Cbz-L-alanine 16:18 with ethylchloroformate 16:19 N-Acylaziridines 13:150 Acylfulvenes 26:713 Acylglycerol 12:392 O-Acylglycosyl bromides 14:172 Acyliminium ion cyclization 1:244; 12:305,320,335 N-Acyliminium ion cyclization 11:290 intramolecular 11:284,285 N-Acyliminium ion-polyene cyclization 12:464
15
N-Acyliminium ion-vinylsilane cyclization 12:453 3-C-nitromethylene derivative 10:412 C-nucleosides 10:337,338,355, 358,388-394 of arylethanals 30:215 ofbioflavours 25:125 ofchlorogenic acid 25:919,930, 935 of furanone 12:13 of glucopyranoside 6:388 of N-substituted amides 10:215 of phosphocombretastatin (disodium salt) A-4 24:406 of potassium kojate 12:261 of silyl enol ether/acetone 11:296,297 of syringaresinol 24:741 of yangambin 24:741 of w-haloalcohol 8:195 of (x-D-glucopyranoside 6:385 parts of 30:707 p-hydroxyacetophenones from 30:731 propiophenone derivative 30:731 pipecolic acid 12:280 D-pyranosides 10:340 Csynthesis of 10:340 reaction with aldehydes 1:584 reaction with ketones 1:584 ribofuranoside 10:376 [3-Cribofuranosyl cyanide 10:356 13-D-ribose 10:337 role of nitric oxide in 26:921-923 sesquiterpenes from 30:706 stannic chloride catalysed 4:328, 329 C-sucrose 11:469,470 synthesis of 11:469,470 synthesis of 24:755-762 testing of 26:376 D-threo-hex-2-enone- 1,4-1actone 20:859 2-Acylindoles 1:51 1-Acylindoles photoisomerisation 1:51 [1,3]-Acylmigration 1:51
N-Acylmuramoyl-peptides 6:393 Acylneuraminic acids 27:104 Acylnitroso Diels-Alder reaction 1:386, 4:606 Acylnitrosocycloaddition 19:355 N-Acylnorreticuline 18:74 Acylovir-resistant HSV-1 25:940 N-Acylpyrrol-2(5H)-ones 13:110,111 3-Acylpyrrol-2(5H)-ones 13:112,113, 141 3-Acylpyrrolidinone 13:121,122,133, 139 3-Acylpyrrolin -2,5-diones 13:114, 125,129 3-O-Acylquinic acids 25:921 5-O-Acylquinic acids 25:921 N-Acylsphingosines 18:714 Acyltetramic acid 21:410 3-Acyltetramic acids 14:97 Acyltransferase (AT) 22:265 Adamantane 9:116 Adaptation 27:529 of plants to selenium 27:529 Addiction 30:799 by analgesic alkaloid 799 1,4-Addition 24:6 of hydride 24:6 syn Addition 8:296-298,304 Addition reaction 12:35-62 of chiral vinyllithium compounds 12:35-62 to c~-methyl-substituted aldehyde 12:35-62 1,4-Addition reaction 14:696,697 Addition-elimination mechanism 11:185,187 for 5-enolpyruvylshikimate 3phosphate synthase 11:185,187 anti-Adduct 30:447 from 3-bromopropyne 30:447 of carrageenans 30:410 of cationic polysaccharide (PS) 30:402 of dextran sulphate 30:410 of fucoidan 30:410 of mannans 30:402 of pentosan polysulphate 30:410 of polyphenols 30:224 of polysaccharides 30:393,395
16 of quinones 30:324-326 of sulphated galactan 30:402 of sulphated polysaccharide (PS) 30:403 of xylogalactans 30:402 of yeast mannans 30:412 on infected vero cells 30:410 Adenanthera pavonina 29:603 Adenine-thymine 22:27 Adenocarcinoma 1:276;26:712 of colon 1:276 Adenocorticorophic hormone(ACTH) 25:265 Adenohypophysical hormones 25:265 Adenosine 22:21;27:394;30:384 conversion of 30:384 from glucose 27:394 from red ginseng roots 27:394 structure of 27:396 Adenosine A1 receptors 25:532 Adenosine A2A 25:532 Adenosine receptors 22:25,20 Adenosine-5'-triphosphate (ATP) 25:948 ;27:820;30:369,384 Adenosine-5 '-diphosphate (ADP) 27:405 5-Adenosyl-L-methionine (SAM) 25:506 Adenosylmethinonine 25:828 S-Adenosyl-L-homocysteine (SAH) 25:509 S-Adenosyl-L-methionine (SAM) 25:509 S-Adenosylmethionin-decarboxylase inhibitor 26:830 S-Adenosyl-methionine 1:408 S-Adenosylmethionine (SAM) methylation 9:42,599,21:316 S-Adenosylmetionine: caffeate 3-0metyl transferase 5:468 Adenylate cyclase activator 25:488 Adenylate cyclase system 25:493 Adenylyl cyclase 25:532 inhibition of 25:532 Aderostenedione 25:419 Adhyperforin 22:645,653;30:612 structure of 30:612 ADI (acceptable daily intake) 27:308 for stevioside 27:308
Adiantum spp. 29:573,580 Adipokinetic hormones 9:487,489 Adipose tissue 30:81 Adipose tissue distribution 26:1130 as syndrome type-lA 26:1130 Adiposin-1 and 2 10:514 inhibitory activity against c~amylases 10:514 Adiposin-D 10:513 Adiposins 10:514 antibacterial activity of 10:514 et-glucosidase inhibitors of 10:513 Adjuvant activity 21:646,650;22:119; 26:55 of Gypsophila 26:55 of Quillaia 26:55 of Saponaria 26:55 Adjuvant induced polyarthritis 25:46 inhibition of 25:46 Adocia sp. 25:695,723,861 ;28:674 adociaquinone A from 28:678 adociasulfate from 28:674 from Great Barrier Reef 28:674 Adociaquinone A 25:862 Adociaquinone B 25:862 Adociaquinones 25:861 Adociasulfates 25:695 Adociidae family 28:664 10-isothiocyanatobiflora-4,15diene of 28:664 spectral analysis of 28:664 ADP-ribosylcyclase 25:535 Adrenaline 22:308;30:58 intravenous infusion of 30:58 a2-Adrenergic 25:530 type G-protein-linked receptor 25:530 Adrenergic activity 23:356 of coumarin 23:335,353,356, 357,368,376,393,550,553 Adrenergic agonists 21:109 Adrenergic alkaloids 21:68 Adrenergic antagonists 21:57;25:530 Adrenergic blocker 22:19 [3-Adrenergic blocking agents 14:473 synthesis of 14:473 c~-Adrenergic neurons 21:18
17 [~-Adrenergic neurons 21:18 ~x-Adrenergic receptor 21:18 [32-Adrenergic receptor 21:51 [3-Adrenergic receptor kinase 21:264 Adrenergic receptors 21:57;22:19; 25:271,530 c~i-Adrenergic receptors 21:90 c~2-Adrenergic receptors 21:90 [32-Adrenergic receptors 27:825 (x-Adrenoceptors 25:30 [3-Adrenoceptors 22:667 Adriamycin 14:474 4-demethoxy analogs of 14:474 synthesis of 14:474,475 Adriamycin-resistant P-333 cell 21:264 Aedes aegypti 9:299;26:439 Aegiceras comiculatium 7:176-178,180, 185,195 Aegiceras floridium 7:176-178 Aegilops ovata 26:187 A egle marmelos 21:599 Aegopodium podagraria 27:687 Aeolanthus suaveolens 22:509,511 in convulsions 22:511 Aeridoteres tristis 5:837 hemoglobin components of 5:837 Aerobacter aerogenes 11:183 Aerobacter ganera 29:311 Aeromenas salmonicida 4:197;23:238; 25:259 A eromonas hydrophila 4:197 Aeroplysinin 21:307;25:718 Aeroplysinin- 1 21:259,260 Aeropyruin pernix 25:720 Aerugidiol 29:90 activity in HPT assay system 29:90 (+)-Aerugin 19:821 Aeruginosin 25:205,799 Aeschynomene indica 25:93 [3-Aescin 21:657 Aesculetin 7:224 Aesculin 7:224;23:357 Aesculus chinensis 29:574,575 Aesculus glabrus 15:191 Aesculus hippocastanum 7:142,143; 21:657,666
escins from 21:666 escins Ia,Ib,IIa and IIb from 21:657 A esculus indica 7:142,143 aesculosides A,B from 7:142 triterpenes of 7:142,143 Aesculus saponins 15:191 Aethiopinone 29:100 activity in CRG assay system 29:100 Aethoxyamericanolide E 23:161 Aferoside A 824 Affinisine 5:123,126;9:179;13:386,429 ~t-Affinity 30:807 in guinea pig brain membranes 30:807 in rat brain synaptosomes 30:807 Affinity chromatography 30:825 8-Affinity 30:807 with deltorphins 30:807 Aflastatin A 28:127,128 as aflatoxin inhibitor 28:128 structure of 28:128 Aflastatin B 28:127,128 as aflatoxin inhibitor 28:128 Aflatoxin B-1 22:266;26:271,304 Aflatoxin B2 23:363 Aflatoxin inhibitor 28:128 aflastatin A as 28:127,128 aflastatin B as 28:127 Aflatoxin M2 14:651-657 Norrish type II reaction 14:651-657 Afraegle paniculata 22:511 as anticonvulsant 22:511 Aframomum aulacocarpos 25:259,266 Aframomum danielli 25:257,260 Aframomum hanburyi K. Schum. 27:17,34 3-acetoxy-5,7-dihydroxy-4 'methoxyflavnone from 27:17, 34 Aframomum pruinosum 27:34 African swine fever virus (ASFV) 30:410,412 effect of marine microalgae on 30:410 in vitro 30:410 transmission of 30:410
18
African trypanosomiasis (HAT, sleeping sickness) 26:784 African trypanosomiasis (HAT, sleeping sickness) 26:784 (+)-Africanol Claisen rearrangement 6:51 Afrocurarine 1:126 Afrormosin isoflavones 27:498,499 Afzelia bipendensis 9:256 bipendensis from 9:256 Agaricales 9:203 Agaricus blazei 28:569 isolation of 28:569 Agarofurans 23:811 ;30:695 Agastache foeniculum 29:571 Agastache rugosa 29:574 Agastanol (diterpene) 29:574 effects on HIV- 1 protease 29:574 Agastaquinone (diterpene) 29:574 effects on HIV- 1 protease 29:574 Agathis robusta 25:252 Agatophyllum aromaticum 21:616 Agavaceae 7:427;21:673 Agave cantala 7:427 Agel-489 13:650 Agelas clathordes 25:860 Agelas dendromorpha 25:792 Agelas dispar 25:706,710,722,777; 28:692 pyridine betaine B of 28:692 Agelas mauritiana 25:688,722,784, 870;28:689 Agelas mauritianus 18:460,467 agelasphins from 18:460,467 Agelas nakamurai 6:28;25:688,712, 780,860;28:670 antispasmodic activity of 28:670 agelasin-B from 6:28 agelasidine A from 28:670 agelasidine B from 28:670 antispasmodic activity of 28:670 Na+/K+-transporting adenosine triphosphate (ATP)ase inhibitor from 28:670 Agelas novacaledoniae 25:710 Agelas oroides 21:270;25:703;26:819; 28:690
Agelas sceptrum 21:270 sceptrin from 21:270
Agelas sp. 6:28;25:709,712,722,779 agelasins from 6:28
Agelas sponge 25:688 Agelas wiedenmayeri 25:712 Agelasidine A 28:670 synthesis of 28:670 Agelasidine B 25:861 ;28:670 synthesis of 28:670 Agelasidines A-D 25:860,861 (+)-Agelasidines B and C 25:860,861 Agelasimine A 25:688,792,793 Agelasimine B 25:688 Agelasimines 25:687 Agelasine 21:79 Agelasphins 25:722 Agelenopsis aperta 19:675 Ageliferin 25:779,780 Ageratina adenophora 5:28 Ageratoriparin 20:282 Ageratum fastigiatum 5:728 Ageratum houstonianum 22:395,396 Age-related mascular degeneration 30:525 role oflutein in 30:525 role ofzeaxanthin in 30:525 Agglutination 30:204 inhibition by hederagenin monodesmosides 30.204 Agglutination inhibitors 2:308,309 Aggregation 25:358,360 ofheme into hemozoin 25:360 of porphyrin and metalloporphyrin systems 25:358 Aggregation pheromone 1:692 of Gnathotrichus 1:692 Aggreticin 5:597 platelet aggregating inhibitor 5:597 Aging 30:224 role of free radicals in 30:224 Aglaia elliptica 26:218 aglaiastatin from 26:220 4'-demethoxy-3',4'-methylenedioxy-methyl rocaglate from 26:218 1-oxo-4'-demethoxy-3',4'-methylenedioxyrocaglaol from
19 26:218 4 '-demethoxy-3 ',4 '-methylenedioxyrocaglaol from 26:218 1-O-formyl-4'-methylenedioxymethylrocaglaol from 26:218 Aglaia odorata 22:511 ;26:220 in convulsions 22:511 pyrimidinone from 26:220 rocaglaol from 26:220 Aglaiastatin 26:220 Aglaonema treubii 24:917 Aglaophenia pluma 5:353 Aglycone 15:362;23:487,515;27:667, 929 anomeric configurations in 27:667 acid-catalysed rearrangement of 23:515 Aglycone-indolocarbazole 21:263 AGM-1470 (TNP-470) 22:262 Agmatine 22:724 Agmatine (1-amino-4-guanidino-butane) 530 Agmenellum quadruplicatum 26:358 Agnuside 29:84 activity in COX assay system 29:84 g-Agonist 30:799,801 dermorphins as 30:799 inhibitory effects of 30:801 8-Agonist 30:799,807 deltorphins as 30:799 [LeuS]enkephalin as 30:807 8-Agonist (D-Ala2) deltorphin II 30:801 evaluation of 30:802 Agonist effect 25:533 of oripainine 25:533 la-Agonist tetrapeptide 30:813 k-Agonist U-50 30:807 activity in GPI assay 30:807 Agonistic activity 21:68,95 Agonists 21:51 Otz-Agonists 8:396-298 Agratis ipsilon 7:397 Agricultural application 27:321 of abscisic acid 27:321 Agricultural pests 28:423 of forage crops 28:423
of fruits 28:423 of ornamentals 28:423 of timber 28:423 of vegetables 28:423 Agrimonia eupatoria 29:581 Agrimonia pilosa 23:396 Agrimonic acid A 23:3963Agrimonic acid B 23:397 Agroastragalaoside IV 25:197 Agroastragalaside I 25:197 Agroastragaloside II 25:197 Agrobacterium aurantiacum 21:299 Agrobacterium radiobacter 21:185 Agrobacterium rhizogenes 15:376,377; 17:395,421; 22:740;26:640,641 Agrobacterium sp. 7:76;25:395,659, 711,878 Agrobacterium tumefaciens 9:386,388; 21:185;22:740;23:267,268;25:395, 399 Agrochelin 25:711,878 Agrocin 21:84 21:185 Agrocinopine 21:185 Agroclavine 11:199,200;21:68 Agrocybe cylindracea 23:139 Agrofoglio 29:461 carbafuranose synthesis by 29:461 Agropyron repens L. 26:696;27:191, 216 allelopathic interaction of 27:21 Agrostemma githago var. githago 26:49 Agyl glycosides 7:53-58 AH-b-X model 27:10 AI-77-A to G 15:390 AI-77-B 15:393,396,397,402,404, 412-418 AI-77-G 15:392 AIBM 21:746 AIBN (2,2'-azobisisobutyronitrile) 6:353;19:340;481 AIDS 2:421-426;21:297,616,661,665; 22:248;30:226,396 mechanism of action of 30:226 AIDS virus 12:245 AIDS-associated lymphoma 21:138 Ailanthinone 7:379,380,398;26:815,816 Ailanthone 7:394,398 Ailanthus altissima 7:392,394;23:296
20
Ailanthus grandis 7:369,381 Ailantinol A 23:317 cytotoxicity of 23:317 Ailantinol-B 23:314,315 Ailantinol-C 23:314,315 Ailantinol-D 23:315 Ajmalicine 21:57,96 Ajmaline 9:183-185;13:403,404,424426;15:469 ;21:73,96,97,102,108 Ajmalinimine 9:183-186 Ajoene 28:432 acaricidal activity of 28:432 against Tetranyehus urticae 28:432 anticoagulant properties of 28:432 E-Ajoene 459,468 Z-Aj oene 468 Ajoenes 26:795,796,797 Ajuga decumbens 29:83,111 Ajuga reptans 29:24 Ajugalactones 20:248 Ajugol 7:455 Akaterpin 28:673 as phosphatidylinositol phospholipase C inhibitor 28:673 stereochemistry of 28:673 Akebia quinata 22:97 Akendo 29:100 activity in TPA bioassay system 29:100 activity in CRG bioassay system 29:100 Akicenin 5:722,723 Akiferidin 5:722,723 Akiferin 5:722,723 Aklavinone 4:317,327-329,333,341, 342;11:121-123 Akuammicine 1:35:1:45;5:123;9:190, 192;14:751 (Z)-Akuammidine 15:466,467 Akuammidine 5:24,123,127;9:171 (E)-Akuammidine (rhazine) 13:403 Akuammigine 9:171 ;25:31 Akuammiline 5:80,126,9:194,195 Akuammine 21:68,72
A1-Abed and Seepersaud 29:460 carbaketofuranose synthesis by 29:460 Alachlor 25:669 Alacocarpines A & B 25:266 ALA-dehydrase 9:604 Alamethicin 21:224 Alane 1:455 Alanine 21:738;22:21 ;25:264,400 Alanine derivatives 30:216 Alanine transaminase (ALT) 25:475 [3-Alaninookadaic acid 5:385,388 Alantolactone 26:463 Alaria sp. 26:1121 Alarm pheromone 6:453,454 n-undecane in 6:453,454 Alaternin 30:321 as antioxidant 30:321 Alatol 18:745 9-epi-Alatol 18:746 Albanin D 28:229 biological activity of 28:229 Albanin F 28:230 biological activity of 28:230 Albanin F and G 4:618 Albanol A 28:17,230 as aromatase inhibitor 28:17 biological activity of 28:230 Albanol B 28:229 biological activity of 28:229 Albartin 7:224 Albati 17:198 Albazoin 17:19 Albicanol 17:14 Albicanyl acetate 17:14;21:318 Albifloranine 9:171 Albiflorin 22:508,528,540 Albioside I 25:95 Albioside II 25:95 Albizzia harveyi 22:511 for epilepsy 22:511 Albizziajulibrissin 25:208;29:603 Albizzia lebbeck L. 22:511 Albizzia sp. 26:1157 Alboinon 23:257 Albomycin 9:555 Alcaligenes eutrophus 1:690;4:39;8:299 Alcaligenes faecalis 23:116;25:718
21
A lcaligenes faecalis var. myxogenes 5:314 (+)-Alchorneine 16:439 [3-Alcohol 19:248 Alcohol and D. Gal N models 25:463 Alcohol consumption 30:374 autistic features in 30:374 Alcohol dehydrogenase 17:479 Alcohol dependence 30:799 Alcohol inversion 1:456,457,459 Alcohol protection 1:558 as MEM ether 1:558 Alcohols 30:442 diastereomeric mixture of 30:442 Alconil 22:171 Alcyonacea 21:272,279 Alcyonidium gelatinosum sp. 18:695; 28:619,716 (2-hydroxyethyl) dimethylsulfoxonium ion from 28:619 Dogger Bank itch by 28:619 Aldehyde oxidase 22:5 Aldehydes 30:431 Aldimine 18:680 Alditols 9:499 Aldobiuronic acid 26:1157 1-Aldo-C-glycosides 10:350,351,389 Aldoheptofuranoses asymmetric quaternization 10:428-432 Johnson-Claisen rearrangement in 10:432-436 Aldohexoses 10:414,415 Aldol condensation 13:448,468;24:728, 729;30:213,215,423,433,472 acid-catalyzed 16:216,220 anti-Aldol condensation 30:435 Aldol condensation-intramolecular cyclization 30:217 Aldol coupling reactions 11:435-439 Aldol cyclization 6:49,50;24:201 2-amino alcohol by 12:411,414 asymmetric 4:327 chiral acetals in 4:329 chiral synthons for 4:491 of c~-sulfinylesters 4:491-494 of aldehyde 12:174,411,414 ofascorbic acid 4:699-705 in (+)-spatol synthesis 6:40,41
stereoselective 12:154 with enolsilyl ether 12:174 with isonitrile 12:411,414 with N-acylimine 12:160 Aldol reactions 13:206;30:438 from alditols 30:438-445 intramolecular McMurry approach 13:602 Aldol stereoselectivity 12:72 Aldol syntheses 30:434 from acyclic aldoses 30:434-438 Aldol type addition 16:656 Aldol type condensation 8:426,427 of aldehydes 8:426,427 with 2-trimethylsiloxy-3methylfuran 8:426,427 Aldolase-catalyzed stereocontrolled 30:423 Aldolases 30:423 in metabolism of 30:423 Aldolization 6:7,9,10,17 Aldol-type cyclization reaction 29:436 in alkaloids synthesis 29:436 Aldol-type reaction 12:36 stereocontrolled 12:36 stereoselective 12:166 Aldose aldehydes 30:446 elongation of 30:446 Aldose reductase 25:263,264;30:697 Aldose reductase inhibition 6:20;21:593 alkaloids in 21:3,20,109 as medicine 21:109 biorational plant protectants 21:109 by (+)-dysideapalaunic acid 6:20 by ion channels 21:3,20 Aldose reductase inhibitor 22:166; 28:691 from Dictyodendrilla sp. 28:691 (1--~ 1)-Aldosyl aldoside 1-thiodisaccharides 8:317-322 (1 ~2)-Aldosyl ketoside 1-thiodisaccharides 8:322-326 Alectoria sarmentosa 5:310,311 Alectoria sulcata 5:310,311 Alexa leiopetala 11:267;12:332,342; 27:255 (+)-castanospermine from 11:267;12:332
22 (+)-6-epi-castanosperime from
12:342 (1S,6S,7R,8R,8aR)-tetrahydroxyindolizidine from 12:332 Alexandrium fundyense 18:703 Alexandrium ostenfeldii 18:703 Alexandrium tamarebnsuis 7:703 Alexandrium tamarensis 17:4;18:703 Alexandroside I 25:214,198 Alexine 7:13,14,10:567,568 Alfalfa 23:343 Alfentanil 30:200 as morphine analogue 30:200 Algae 9:321 ;30:521 Algal and cyanobacterial toxicity 26:376 testing of 26:376 Algicidal activity 26:358 Alginasic 24:995-998 enzymatic activity of 24:995-998 Alginic acid 26:1150,1151,1152 Algoane 25:804 Alianthus malabarica 21:273 Alicyclic amino acid 22:293 Aliphatic pentaene phytofluene 30:518 Alizarin 25:543,544;26:635-640,642, 649,656-658,670-673,875 ;30:336 1-methylether of 26:658,673 2-methylether of 26:659 synthesis of 26:635-637,642 use for dyeing 30:336 S-Alk(en)ylcysteine sulfoxides 457 Alkaline hydrolysis 27:671 Alkaline phosphatase 21:160 Alkaline phosphatase activity 26:378, 382 Alkaloid 23:241;24:527-533;30:563, 596,799 as analgesic 30:799 as antiviral compound 24:527-533 in vivo antimalarial assay 30:596 in vivo intrinsic activity of 30:596 molluscicidal activity of 7:427 Alkaloid 223A 29:439 2,3,5,6-tetrasubstituted piperidine moiety of 29:440 as trialkyl-substituted
indolizidine class member 29:439 C-6 epimer synthesis in 29:442 conjugate addition reaction in 29:441 homologs of 29:439 of dart-poison frog alkaloid 2071 29:444 stereochemistry of 29:444 stereoelectronically favored axial attach in 29:443 stereoselectivity of 29:443 structure of 29:439 Alkaloid AG- 1 1:127 Alkaloid glycoside 24:123,132,133 Alkanoic acid 21:612 Alkanol 7:231 asymmetric hydration of alkene 13:451 asymmetric hydroboration of alkene 13:451,452 oxyamination of alkene 12:411, 413 photochemical additions to alkene 1:642 Alkenals 2:10 A3'4Alkene 12:22 Alkenols 2:10 o-Alkenyl dehydroglycosides 3:245 Alkenyl phenols 7:427 molluscicidal activity of 7:427 6-Alkenyl-4-oxapyran-2-ones 10:340 by enolate Claisen rearrangement 10:340 Claisen rearrangement of 3:245 hydroboration of cis-alkenes 8:471,472 thermolytic cyclization of 6:429 Alkenylcopper-phosphine complex 8:189 Alkenylhydroquinones 9:321,329 (Z)-N-Alkenylinitrone 19:29 N-Alkenylurethanes 19:29 Alkhanin 7:231 [3-Alkoxy diazo ketones 12:27,28 3-[(c~-Alkoxy)-Gt-methoxy]-2thioxopyrrolidines 26:1097
23 3-[(oc-Alkoxy)-~x-methylthio]-methyl-2thioxopyrrolidines 26:1097 1-Alkoxyalkyl-cz-glucosides 7:51 Alkoxyalkyl-[3-glucosides 7:51 (~,-Alkoxyallyl) stannanes 11:442,443 Alkyl 1-thioglycoside 8:347 Alkyl 1-thioxylosides 8:315 Alkyl 4-thiodisaccharide 8:332,333 sec-Alkyl boronic ester 11:409,411,412 Alkyl citrates 24:433 structure of 24:433,434 Alkyl esters 27:334 of Abscisic acid 27:334 Alkyl ketones 14:645 Alkyl maltotrioside 8:346,347 Alkyl phenols 21:591 Alkyl quinones 5:821 c~-Alkyl c~-amino acids 10:411 Alkyl [3-D-galactoside 8:316 2-Alkyl- 1,4-naphthoquinones 5:823,824 4-Alkyl-2-buten-4-olides 3:166,167 3-Alkyl-5-arylimidazolidinediones 30:198 as CB~ cannabinoid receptor 30:198 as pharmacophore 30:198 tra ns-2-Alkyl-5-h ydro x yp iperi dines 13:486 3-Alkyl-8-hydroxy-3,4-dihydroisocoumarins 15:386 Alkylated p-terphenyls 29:291 xylerythrin group of 29:291 Alkylation 10:408,409;14:491-499; 24:2,10,11,14,22,23,25,201,210,749; 30:627 N-Alkylation 16:99,104 reductive 16:99,104 with D-glyceraldehyde 16:99,104 with L-glyceraldehyde 16:99 O-Alkylation 6:385 ~,-Alkylation 6:76,77 in (+)-sinularene synthesis 6:76,77 S-Alkylation 8:214;13: 145 intramolecular 13:145 Alkylcysteine sulfoxides 23:458 1-N-Alkyl-deoxynoj irimycins 7:46
3-C-Alkyl-enitols 10:344,345 30-Alkylphenol 21:592 3-Alkylphenols 9:323,329,338,346 3-Alkylpiperidine alkaloids 24:575-579, 581-584,588-605,611-670 monomers of 24:575-579, 594-605 N M R of 24:581-584 polycyclic diamine alkaloids 24:611-662 structures and properties of 24:575-605 Alkylresorcinol 30:159,167 as drug 30:159 Alkylresorcinol molecules 30:163 interaction of 30:163 5-Alkylresorcinols 21:592 Alkylresorcinols 9:328,338 6-Alkylsalicylic acids 21:592 (S)-4- Alkylthiazolidin-2- thio ne derivative 12:164-168 Alkyl-type phosphoramides 14:286 Alkylxanthates 8:316 Alkyl-13-D-glucopyranosides 7:52 Alkyl-[3-D-glucosides 7:50,51,104,105 o~-Alkyl-[3-hydroxyproline moiety 28:367 construction of 28:367 Alkynols 2:14-16 Alkynyl alcohol 12:2413Alkynyl Grignard reagents 6:448 reaction with 1-methoxycarbonyl pyridinium chloride 6:448 reaction with 2-methylpyridinium salts 6:429 Allamandicin 16:299 antifungal activity of 16:299 antileukemic activity of 16:299 antimicrobial activity of 16:299 cytotoxic activity of 16:299 Allamdin 16:299 antifungal activity of 16:299 antileukemic activity of 16:299 cytotoxic activity of 16:299 Allele 30:376 Allelochemical 9:387,21:107 Allelochemical alkaloids 21:103
24 Allelopathic activities 20:391 ;21:109; 24:845;28:483 of natural podolactones 28:484 of synthetic podolactones 28:484 Allelopathic activity 21:109;28:483 of natural podolactones 28:484 of synthetic podolactones 28:484 Allelopathic agent 26:187 Allelopathic interactions 27:214-218 of Agropyron repens L. 27:216 ofAvenafatua L. 27:215 ofAvena sativa 27:216 of Avena strigosa L. 27:215 of Lactuca sativa L. 27:215 of Secale cereale L. 27:125,216 of Taraxacum officinale Wigg. 27:215 of Triticum aestivum L. 27:215 of Zea mays 27:215 Allelopathy 24:867;25:658 bioassay of 24:867 Allene 5:370 Allene epoxide 8:36 rearrangement of 8:36 [3-Allenic amides 21:386 Allenylindium 30:19 Allenyltin 12:170,172 Allenylzinc reagents 30:19 Allergenic dermatitis 2:277,280-281 Allergenic property 30:157 of anacardic acid 30:157 Allergenicity problems 27:315 of Stevia 27:315 of stevioside 27:315 Allergen-specifc IgE 30:773 Allergen-specific Th2 response 30:776 Allergic encephalomyelitis 21:135 Allergic inflammation 30:55 role of natural products in 30:55 Allergic inflammatory disease 30:69 use of Scutellaria baicalensis in 30:69 Allergic reactions 30:773 Allergy inhibitors 5:759 Allergy processes 30:225 role of leukotrienes in 30:225 Allescheria boydii 26:227 Allicin 26:493
Alliin 23:341,457,458,461 formation of 23:461 from S-allyl 7-glutamylcysteine 23:461 Alliinlyase 23:457 Allium ascalonicum L. 22:511 Allium cepa L. 22:511 ;29:341,578, 580,589 for epilepsy 22:511 for epilepsy and infantile convulsions 22:511 Allium macrostemon 21:670 furostanolglycoside from 21:670 Allium sativum L. 22:511,29:684; 23:341,455,481;26:493,796,1135; 28:415 for convulsive affections 22:511 Allium ursinum 29:595,684 (+)-alloaromadendrane-4,10-diol from 14:379 Alliums 23:469 Allocolchicine analogues 29:378 allocolchicinoids total synthesis of 29:378 Allocolchicinoid synthesis 29:364 for biological screening 29:366 from colchicine 29:364 role of colchicine tropolone ring in 29:3 <4 Schmidt ,earrangement in 29:365 to prodrug of N-acetylcolchinol 29:366 Allocolchicinoids 29:356 allocolchiceine as 29:365 (-)-androbiphenyline as 29:358 colchibiphenyline as 29:358 dibenzocycloheptylamines as 29:358 N-acetylcolchinol as 29:365 effects on tumour vasculature 29:366 in clinical trials 29:366 SAR studies of 29:359,365 semi-synthetic analogues of 29:359 synthetic analogues of 29:359 X-ray analysis of 29:359
25 Allocolchicinoids total synthesis 29:373,379 by Banwell 29:377,378 by Boy~ and Brossi 29:378 by Cook 29:375 by Rapoport 29:374 by Wulff 29:379 intramolecular oxidative biaryl coupling in 29:376 of (-)-N-acetylcolchinol methyl ether 29:375 of (+)-colchinol methyl ether 29:374 of (+)-jerusalemine 29:377 of (+)-N-acetylcolchinol 29:376 of allocolchicine analogues 29:378 ofcolchinol analogue 29:378 of positional isomers 29:378 phenanthrene ring enlargement in 29:374 stereocontrolled approach to 29:379 (+)-Allokainic acid 26:478 Allolobophora sp. 30:828 from Lumbricidae family 30:828 (+)-Allomatrine 30:205 activation of kappa-opioid receptors by 30:205 activity in acid-induced abdominal contraction test 30:205 antinociceptive effect of 30:205 SAR of 30:205 Allomelanin 9:231 D-Allomethylpyranose 15:190 Allomones 8:219,220 Allomyces macrogynus 5:276,6:544 Allomyces sp. 5:276 Alloporin 30:533 (+)-Allopumiliotoxins 19:60,61-63,65 Allopumiliotoxin 267 A N-oxide 12:294 from Dendrobates speciosus 12:294 Allopurinol 26:793 Allopylus africanus 22:511 for convulsions 22:511 Allosecurinine 14:657 Allosedamine 10:677
(+)-Allosedamine 13:474 (-)-Allosedamine 13:475,477 Allosorelline 11:320 Alloxan 26:759 (3R,3R')-Alloxanthin 6:153 Alloxanthin 6:154,155 (-)-Alloyohimban 10:155;18:384 Alloyohimbane 25:5,20 All-trans procyanidin dimer B3 21:522 Allyl 2,3-O-benzyl-4-O-tert-butyldimethylsilyl-c~-L-rhamnopyranoside 8:368 Allyl 3,5-O-isopropylidene-2-O-triflyl[3-D-lyxofuranoside 8:330 Allyl acetates 4:21,49 isomerization of 4:49 allylation of 4:21 ~-Allyl complexes 4:398 S-Allyl cysteine sulfoxide 23:461 Allyl ether 1:453 isomerization to vinyl ether 1:453 Allyl formate-induced liver injury 25:466 Allyl glycidyl ether 10:588,589 cyclization of 10:588,589 oxetane ring formation by 10:588,589 ct-Allyl glycosides 10:348 by anti S N 2 displacement 10:348 from D-glucal triacetate 10:419 Allyl isocyanide 12:113 from allyl iodide 12:113 from silver cyanide 12:113 Allyl manganese reagent 4:34,344 S-Allyl mercaptocysteine (SAMC) 23:463,468,472 Allyl methanethiosulfinate 23:467 ~-Allyl palladium complex 4:500; 10:214,215 ~l-Allyl Pd alkylation 10:10-13 intramolecular 10:10-13 Allyl sulfones 3:23 addition to enones 3:23 Allyl sulfoxide anions 3:21,22,435 addition to enones 3:21,22 synthesis of 3:435
26
Allyl thiosulfinate 23:459 Allyl trans-1-propenyl thiosulfinate 23:459 Allyl tributylstannane 12:425,426 S-Allyl-T-glutamylcysteine 23:461 N,N-Allyl,c~-methyl benzylamine 8:403-404 (E)-Allyl- 1-propenyl thiosulfinate 23:467 (-)-5-Allyl-4-methoxy-2-oxazolidinone 12:419 (4R,5R)-5-Allyl-4-methoxy-2oxazolidinone 12:431,432 (4S,5S)-5-Allyl-4-metho xy-2oxazolidinone 12:432,433 (3S,4S)-cyclohexylstatine from 12:432,433 (3S,4S)-statine from 12:432,433 Allyl-9-BBN 14:482 Allylamines 12:411,414;22:58,60,63 2-amino alcohol by 12:411,414 cyclocarbamations 12:411,414 Allylamines Allylation 1:604-610;24:198 diastereoselective 1:604-610 of 2-acetylcyclohexanone 10:412 of FAMSO 6:315,316 with allyl acetate 10:412 Allylation reaction 12:484,14:474; 30:452 stereochemical outcome of 30:452 O-Allylation-Claisen rearrangement 12:269 Allylboration 8:477,478 Allylboronate 1:311,312 stereoselective addition to glyceraldehyde 1:311,312 zt-Allylcation complex 3:82,83 Allylcerium 8:24 Allylchromium reagent 30:24 Allylchromium species 3:81 coupling with carbonyls 3:81 medium ring compounds from 3:81 [3-Allyldiisopinocamphenylborane 19:14 C-Allylfuranoside 3:215
ot-Allylglucosides 3:214,215 synthesis of 3:214,215 (S)-Allylglycine 13:512 Allylic acetoxylation 16:420 Allylic alcohol 12:46,47 allylic aldehyde from 12:46,47 amides from 14:722,723 asymmetric cyclopropanation of 14:490,491 biomimetic cyclization of 14:717-720 by Claisen rearrangement 14:722,723 epoxidation of 10:39,40 2,3-epoxy alcohol from 14:570 from (R,R)-2,3-butanediol 14:490 from acetylenic ketone 11:424 from D-glucose 10:428-438 from dimethyl -tartrate 11:267,268 Johnson-Claisen rearrangement of 10:428-438 mesylation of 4:172,173 one-carbon homologation 3:238 oxidation of 12:46,47,16:594 preparation of 11:424 Sharpless epoxidation of 14:570 transformation of 30:20 with MnO2 12:46,47 with VO (acac)2-TBHP 10:39,40 Z-Allylic alcohols 4:203 cis-hydroxylation of 4:203 Allylic bromination 6:207 Allylic carbocation 4:172-174 asymmetric epoxidation of 4:172-174 Allylic carboxyl group 3:487 phytochemical removal of 3:487 Allylic C-O bond cleavage 1:557,558 with dissolving lithium/amine reduction 1:557,558 Allylic displacement reactions 16:397 palladium catalyzed 16:397 Allylic ethers 4:116 hydroboration of 4:116 Allylic glycolate esters 10:437 Ireland-Claisen rearrangement of 10:437
27 Allylic hydroxylation 1:535;6:200,201 with SeO2/tert-butylhydroperoxide 1:535 Allylic oxidation 3:448;6:126,159,162; 8:197,198;11:11,40,41;12:311; 16:420,669;24:36,37,56-58, 72-74,79,89,90,179,180,186,187 of perezinone 5:722 with Collins reagent 11:83,84 with manganese dioxide 11:356, 357 with SeO2 1:549,550 Allylic polyprenols 8:66,67,72 synthesis of 8:66,67,72 Allylic radicals 4:525 reductive elimination of 4:525 Allylic rearrangement 4:556;6:159; 14:191 ;16:305,617,669 Allylic strain 6:122;14:553 Allylic sulfoxide rearrangement 1:560, 564 Allylic [~-hydroxysulfoxides 4:503,504 stereoselective hydroxylation 4:503,504 Z-Allylic [3-ketosulfoxides 4:509,510 synthesis of 4:509,510 S-Allyl-L-cysteine (SAC) 23:469 Allylmetal additions 8:16 a-Allyloxy anions 3:248-250 [2,3 ]-Wittig rearrangement of 3:248-250 Allylsilane 14:482 Allylstannane 1:247,256,312,313; 10:17-25 Allylsulfenic acid 23:463 Allyltin derivatives 11:442,443 nucleophilic addition by 11:442, 443 Allyltitanium phosphorus reagent 30:17 Allysilane 1:314 Alnus firma 17:359,364 Alnus glutinosa 19:246 Alnus hirsuta 17:360-361 Alnusjaponica 17:360,368 Alnus maximoviczii 26:883 Alnus rubra 17:359,26:596 Alnus serrulatoides 17:359-360 Alnus sp. 17:358-359,368,375
Alnusdiol 17:368;26:895 Alnusone 17:368;26:895 Alnusonal 26:895 Alnusonol 17:368 Alnusoxide 17:368,371 Alocasia macrorrhiza 29:603 Aloe arborescens 30:309 against colon carcinogenesis 30:309 Aloe barbadensis 30:341,412 against coxsackie virus 30:412 Aloe sp. 22:580;30:338 in acute liver injury 30:338 Aloe vera L. 22:511 for epilepsy and convulsions 22:511 Aloe-emodin 30:306 structure of 30:306 Alopecia 21:158 Aloperine 14:754 ent-8-Alpha-hydroxy-lamba- 13,14-dien 25:263 Alpha mannosidase II 22:30 Alpha-bungarotoxin 22:17 Alpha-chaconine 22:36 Alpha-solanine 22:35 Alpha-tomatine 22:32 Alphidium pliciferan 25:895 Alphinia speciosa 21:599 Alphitolic acid 28:62 antimicrobial activity of 28:62 Alpinenone 814 Alpinetin 23:802,808 (+)-Alpinetin 23:821 Alpinia blepharocalyx 26:886,887,902 Alpinia conchigera 26:883 Alpinia galanga 23:800,24:302, 25:257,260 Alpinia katsumadai 17:362,375 Alpinia officinarum 17:362-363,375, 26:883 Alpinia oxyphylla 17:362,375,379, 24:273 Alpinia sieboldiana 17:362 Alpinia sp. 17:358;26:905 Alpiniol 23:812 Alpinmetin 23:808 Alpinolide 23:813 synthesis of 23:813
28 Alpinone 22:473 Alrestatin 22:166,171 Alsidium corallinum 26:479 Alsidium helminthocorton 26:478 Alstocraline 13:395 Alstonia augustifolia 13:422 Alstonia boonei 22:512,29:574,583, 585,587 Alstonia constricta 1:125,214-217,219, 2:369 Alstonia macrophylla 5:135,154-157 Alstonia scholaris R. Br. 5:135,137, 138,13:383 ;22:512 for epilepsy 22:512 Alstonia venenata R. Br. 1:125;22:512, 519 for epilepsy 22:512 Alstonine 1:125;26:1060 Alstopicralamine 9:185,186 Alstovine 1:36 Altenaria kikuchiana 22:273 Altermaria mali 12:400 Alternaria alternata 21:217;22:263; 24:936;25:305,307,672;26:451; 27:793;28:114 diketopiperazines from 24:936 Alternaria cinerariae 11:194 dehydrocurvularin by 11:194 Alternaria helianthi 26:1091 Alternaria kikuchiana tanaka 5:598; 15:385 Alternaria longipes 28:114 Alternaria solani 15:346;25:302,303, 307,316 Alternaria sp. 9:203 Alternaria tenuis 9:300;28:114 Alternatamide A 25:774 Alternatamide B 25:774 Alternatamide C 25:774 Alternosides I-V 27:41,44,45 as sweetness inhibitors 27:41 structures of 27:41,45 Alteromonas luteoviolaceus 21:298 Alteromonas rawa 25:820 Alteromonas sp. 21:411,259;25:717,719 alteramide A from 21:411 Altertogorgia sp. 25:695 (+)-Altholactone 19:468
Altholactone 19:498 biological activity of 19:498 Altholactone (goniothalenol) 9:393 Altohyrtin 25:761 Altohyrtin A 25:727 Aluminium hydride 3:474 selective reduction with 3:474 Alutera scripta 5:390 Alvaxanthone 28:229 biological activity of 28:229 Alycoprotein-rich substance (CVS) 30:776 against experimental metastasis 30:776 antitumor effect of 30:776 Alysine B 634 Alysine C 23:634 Alysine D 23:634 Alzheimer dementia progression 21:585 Alzheimer's diseases 14:637;21:748, 749;22:343 ;30:504 (-)-physostigmine for 14:637 Alzheimer's disease therapy 25:530, 536,710 Amadori rearrangement 18:680 Amalan 26:140 Amalgam procedure 14:746 Amalhia alternata 25:776 Amaloride acetate 23:31511Amanatdine 24:489 dmanita agaricus 9:203 Amanita muscaria 22:737;23:115,118, 134;29:292 Amanita phalloides 5:496;21:96 Amantadine 27:108 for treatment of influenza A 27:108 Amaranthus caudatus L. 27:217;29:607 dmaranthus hypochondrionacus 29:607 Amaranthus retroflexus L. 27:217 Amarathine 26:305 Amariin (hydrolysable tannin) 29:572 effects on HIV- 1 protease 29:572 Amarillidaceae alkaloid 25:536 galanthamine (galantamine) 25:536 Amarogentin 7:490;26:806,807 Amaroswerin 7:490
29 Amarouciaxanthin A 6:136,142 Amarouciaxanthin B 6:151,152 Amaryllidaceae 22:29 Amaryllidaceae alkaloids 22:5; 26:608-613,615-620 Amastatin [(2S,3R)-3-amino-2-hydroxy5-methylhexanoyl-L-valyl-L-valylL-aspartic acid)] 12:434 leucine aminopeptidase inhibitor of 12:434 Amata sp. 5:225,252 Amathamides C,D,E and F 18:715 Amathaspiramide E 25:782 Amathia alternata 17:85 Amathia convoluta 17:75,18:715; 25:786 Amathia genus 17:82 Amathia wilsoni 17:92,95,97,101; 18:693;25:782 Amaurornis phoenicurus 5:83 hemoglobin components of 5:83 Amberlite IR-45 15:460 Amberlite IRA-400 12:317 Ambigol A 25:792 Ambigol B 23:342;25:792 Ambliofturan 25:688 Amblyomma americanum 25:795 Amblyomma hebraeum 28:396 Amblyomma sp. 28:394,397 Amblyomma variegatum 28:395 repellent properties of 28:395 Ambrosanolide 16:140;29:90 activity in EPP assay system 29:90 Ambrosia maritima 7:427 Ambrosia peruviana 14:379 Ambrosia sp. 25:138;26:437 Ambrox 25:253;26:394 Amenanthus retroflexus 7:398 Amentoflavone 22:429;25:545 Amentoflavone (3',8"-biapigenin) (biflavone) 29:578 effects on ACE 29:578 American trypanosomiasis (Chagas disease) 26:784,798 Americanol A 26:270 Americanolide A 23:161 Americanolide B 23:160 Americanolide C 23:161
Americanolide D 23:161 Americanolide E 23:161 Americanolide F 23:161 Amerlyst A-21 19:131 Ames test 22:682;27:303,304 AMI calculations 30:542 AMI molecular orbital 22:599 AMI molecular orbital calculations 30:541 Amicetin 4:234,240,242 Amicoumacin A, B and C 15:388 Amide cyclisation 4:546 Amidiol (taraxast-20(30)-ene-3 [3,16[3diol) (triterpene) 29:585 against bacterial diseases of rice plants 29:480 as neuraminidase inhibitors 29:464 biological profile of 29:480 effects on CHY 29:585 effects on glycosidase enzyme 29:480 in structure-based drug discovery 29:464 Amidoalkylation 10:108 intramolecular 10:108 Amidoalkylation reagents (Nacyliminium ions) 13:473-518 Amidocarbonylation 16:408 Amidocyclization 1:382 Amiloride-binding proteins 26:1268 Amination 6:429;16:438 intramolecular 6:429;16:438 Amines 6:429 formation from ketones 6:429 photosensitized oxidation of 16:604 reductive animation of 6:429 D-allo-~-Amino acid 11:460,461 synthesis of 11:460,461 L-allo-c~-Amino acid 11:460,461 synthesis of 11:460,461 (x-Amino acid 12:115,435-438 as chiral building blocks 1:678-684 by hetero Diels-Alder adducts 12:435,436 conversion to amino sugars
30 4:111-156. synthesis of 12:435-438 Amino acid 16:395-414,604;23:234; 24:799 as chiral synthons 4:625 by a-halo boronic ester 11:417-420 non-protein 24:779 photooxidation of 16:604 simple derivatives of 23:234 synthesis of 11:417-420, 13:507-516,16:395-414 Amino acid decarboxylase (AADC) 30:384 Amino acid pathway 21:213 metabolites derived from 21:213 D-Amino acids 12:158,159 by hetero-Diels Alder reaction 12:158,159 cyclization by UGl-reaction 12:116 cyclization of 12:115,116 D-lactams from 12:115 synthesis of 12:155,158,159 (x-Amino acids/esters 1:331-338 conversion to azomethine ylides 1:331-338 decarboxylation of 1:331-336, 337 imines from 1:331 Amino acrylic acid 23:463 Amino acylase 1:678-680 for synthesis of c~-amino acids 1:678-680 Amino alcohol 11:298,299 benzyl-protected 11:298,299 with aldehyde 11:298,299 2-Amino alcohols 12:411,414 by aldol reaction 12:411,414 by cyclocarbamation 12:411,413 by electrophilic addition 12:411, 414 by Michael reaction 12:411,413 by nucleophilic addition 12:411, 413,414 by oxyaminations 12:411,414 by reduction 12:411,414 by ring-opening of oxirane
12:411,413 from 2-oxazolone 12:411-444 synthesis of 12:411-444 a-Amino aldehydes 12:411,414 2-amino alcohol by 12:411,414 in [4+2] cycloaddition 4:111 in Diels-Alder reaction 4:120 metalloorganic addition to 4:124 N,N-diprotected 4:124 nucleophilic addition of 12:411, 414 preparation of 4:113,114 N, O-protected 4:130 ?'-Amino butyric acid 25:548 y-Amino butyric acid (GABA) 25:517, 519,520 e-Amino caproic acid (e-ACA) 30:836, 844 Amino carbonylation 14:568 intramolecular 14:568 palladium (2+) catalyzed 14:568 a-Amino ketones 12:411,414 2-amino alcohol by 12:411,414 reduction of 12:411,414 steroid-pyrazine dimers via 18:885-887 Amino sugars 4:115-118 synthesis from glycine 4:115-118 synthesis of 13:190-207 4-Amino- 1",6"-anhydro-2",3 ",2',3', 6', 2,3-hept-O-benzyl-4,6- dideoxy-[3maltotriose 10:508,509 2-Amino- 1,3-azulenedicarboxylate 14:339 2-Amino- 1,4-benzoquinone-3carboxylic acid 26:995 2-Amino-2,3-di-deoxyhexoses 14:145 5'-([(Z)-4-Amino-2-butenyl]-methylamino)-5'deoxyadennosine 26:830 2-Amino-2-deoxy-D-galacto-Dgalactans 5:298 2-Amino-2-deoxy-D-glucose 1:512 2-Amino-3,6-dihydroxy-benzoic acid 26:979 2-Amino- 3- [5-deoxy- 5-(dimethylassinoy)-/3-D-[ribofuranosyloxy]-2-
31
hydroxy-propene- 1-sulfonic acid 25:867 1 -(4'-Amino-3 '-bulte nal- 2 '- yl)- [3carboline 26:1087 3-Amino-3-deoxy-D-mannose 12:314 3-Amino-3-deoxynucleosides 4:240 synthesis of 4:240 3-Amino-3-deoxysugars 4:150 synthesis of 4:150 a-Amino-3-hydroxy-5-methyl-4isoxazole prionic acid (AMPA) 25:529 2-Amino-3-hydroxy-benzoic acid 26:972 2-Amino-3-hydroxycyclopenten-2-one 21:398,405,409 20-Amino-3-hydroxycyclopenten-2-one 21:405 2-Amino-3-phenoxazionone 26:986 2-Amino-4,4-a-dihydro-4 a, 7-dime thyl3H-phenoxazin-3-one 26:986 4-Amino-4-deoxy-D-mannose 12:314 1-Amino-4-methylpiperazine 23:59 2-Amino-5-[(2'-carboxy-6'-hydroxy phenyl)-amino]- 1,4-benzoquinone-3carboxylic acid 26:977 2-Amino- 5a -deoxy-a-D L-glucopyranose 13:203 Amino-5-hydroxybenzioc acid (AHBA) 23:79 Amino-5-hydroxybenzoic acid 21:42133-Amino-5-hydroxyl-coenzyme A 23:89 2-Amino-5-nitrotoluene 13:442 6-Amino-6-deoxysugars 4:111,127 from a-amino acids 4:111,127 6-Amino-6-deoxyuloses 4:124 synthesis of 4:124 2-Amino-6-hydoxy-4-methyl-8-oxodecanoic acid 21:225 5-Amino-7-methoxy-2,2-dimethylchroman 13:358,359 synthesis of 13:358,359 Aminoacyl-tRNA 21:98 (L-a-Aminoadipoly)-L-cysteinyl-Dvaline 8-(LLD ACV) 11:211-213
cephalosporin C from 11:211-213 penicillins from 11:211-213 5'-Aminoalkyl oligonucleotides 4:294, 295 synthesis of 4:294,295 Aminoalkylated oligonucleotides 4:306 Aminoalkylindoles 30:196,197,198 as cannabinoid receptors ligands 30:197 Aminoalkylindoles 30:196,197,198 structure of 30:197 4[3-Aminoaniline 26:162 synthetic derivatives of 26:162 (+)-9-Aminoaporphine 16:516-517 m-Aminobenzoic acid 21:401 p-Aminobenzoic acid 21:401 2-Aminobenzothiazole 26:162 synthetic derivatives of 26:162 p-Aminobenzyl alcohol 21:162 O-Aminobenzylalcohol 18:164 p-Aminobenzylcarbamate 21:169 2-Aminobenzyltetrahydroisoquinoline 18:73 Aminobisabolene 26:1201 a-Aminobutyrate 21:226 ~,-Aminobutyric acid (GABA) 30:782, 784 as inhibitory neurotransmitter 30:782 effects on blood pressure 30:784 effects of 30:784 y-Aminobutyric acid (GABA) 30:782, 784 accumulation of 30:782 9-Aminocamptothecin 13:655 Aminocarbafuranoses 29:462 as building blocks 29:462 diversity-oriented synthesis of 29:463 in structure-based drug discovery 29:464 starting materials for 29:464 Aminocarbapyranoses 29:480 as carbasugars 29:480 as validamine 29:480 naturally occurring 29:480 valienamine-type carbaglycosyl
32 amine as 29:480 valiolamine as 29:480 Aminocholine 24:913 contraction by 24:914 primary structures of 24:913 Aminocoumarins 18:978 Aminocyclitol 13:212,14:147 Aminocyclitol fortamine 4:118 Aminocyclitol inhibitors 10:517-524 (IR, 2S)-2-Aminocyclopentanecarboxylic acid (cis pentacin) 22:273,274 2-Aminocyclopentanecarboxylic acid 22:299 1-Aminocyclopropane- 1-carboxylate (ACC) 25:372 1-Aminocyclopropane- 1-carboxylic acid oxidase 26:935,950 Aminodeoxyhexosyl-purines 4:238-248 synthesis of 4:238-248 Aminodeoxyhexosyl-pyrimidines 4:238-248 synthesis of 4:238-248 9-Aminoellipticine 22:27 Amino-epoxides 12:351 Aminoepoxycyclohexanone 21:399 2-Aminoethanethiol 8:317 2-Aminoethyl phosphonic acid 2:304-309 3-Aminoflavones 27:926 for cytotoxicity 27:926 2-Aminofluorene 8:377,388 Aminoglycopyranoses 7:47 [3-glactosidase inhibition with 7:47 Aminoglycoside antibiotics 22:58 Aminohexose derivatives 1:25-27 synthesis of 1:25-27 Aminoimidazole 21:270;23:257 2-Aminoindan-2-phosphonic acid (AIP) 25:674 5-Aminolevulinic acid 21:398 5-Aminolevulinic acid (ALA) 9:591, 593,601,603,606 Aminolysis 12:279 intramolecular 12:279 of disaccharide lactone 6:407 of MurNAc 8-1actones 6:393 Aminomethyl bilane (AMB) 9:597
a-Aminonitriles 14:716-718 formation of 14:716-718 via Polonovski reaction 14:716-718 2-Aminonucleosides 4:238 fusion reactions for 4:238 synthesis of 4:238,239 6-Aminonucleosides 4:248 4-Aminooctanal diethyl acetal 6:445,447 condensation of 6:445,447 with diethyl-3-oxo-glutarate 6:445,447 with ethanal 6:445,447 5-Aminooligonucleotides 4:294-292 synthesis of 4:294-292 2-Aminooxetanocin A 10:619,620 antiviral activity of 10:619,620 Aminopentanal 14:739 5-Aminopentanol 21:107 Aminopeptidase B 10:629,646,652 p-Aminophenyl- 1,4,4'-trithiocellotrioside 8:344,346 p-Aminophenyl- 1,4-dithiocellobioside 8:351 20c~-Aminopregn-5-en-3 [3-yl- [3-Dglucoside 5:128 2- [3-Aminopropylidene]- 1,3-dithiane 12:335 4-Aminoquinoline compounds 25:343, 345 quinolinemethanol derivatives 25:343 Aminoquinone 5:437 immunosuppressive effect of 5:437 Aminoresorcinol 26:1272,1273 Cu(II)-Aminoresorcinol 26:1273 4-Aminosampangine 23:6 Aminosidine (paromomycin) 26:831 Amino-substituted morphan analogue 30:199 structure of 30:199 7-Amino-substituted Neu5Ac derivatives 30:426 synthesis of 30:426 via azido derivative 30:426 Aminotransferase activity 19:650 Aminotriazole oxidation 4:548
33 4-Aminouncleosides 4:241-247 D-ct-Aminouronic acid 11:459,460 synthesis of 11:459,460 L-c~-Aminouronic acid 11:459,460 synthesis of 11:459,460 6-Aminovalerookadaic acid 5:385,388 o~-Amino-[3-carboxymuconic-~-semialdehyde 26:970 (3 R)-?-Amino-f3-hydroxybutyric acid 12:434 biological activity of 12:434 as central inhibitory transmitter 12:434 4-Aminoquinoline (chloroquine) 26:781 Aminyl radical heterocyclization 1:292 of chloramines 1:292 Amipurimycin 1:398,404-410,4:246, 11:430,433 Amipurimycin 22:273 Amisine 20:234 Amistar 22:250 Amitermes evuncifer 14:452,463 evuncifer ether from 14:452,463 Amitermes excellens 14:450-452 amiteol from 14:450-452 A mitermes messinae 14:452 evuncifer ether from 14:452 Ammania baccifera 9:65 sesquiterpenes from 9:65 Ammanol 9:65 Ammi majus 23:337 Ammi sp. 29:579 Ammi visnaga 23:352;29:571 (+)-Ammodendrine 15:520 Ammodendrine 21:97 Ammonium D- 10-camphor-sulfonate 15:425 Ammonium glycyrrhizin 15:5 Ammonium nitrate 2:412,413 Ammonolysis 16:97,98 with ammoniacal methanol 16:97,98 Ammophila fernaldi 5:224,232,253 Ammophila nigricans 5:224,232,252 Ammophila procera 5:225,232,252 Ammophila urnaria 5:223,224,232,252 Amodiaquin 22:148 Amodiaquine 25:344,348
Amoebicidal activity 6:485;26:458 of emetine 6:485 of 1,2-secoemetine derivatives 6:485 Amoebicides 7:398 Amomum 23:817 Amomum cardomon 24:272 Amomum compactum 24:274 Amomum xanthiodes 24:272 Amoora 21:124 Amopyroquine 25:344 Amorpha fruticosa 24:225,227 Amorphane 15:247;25:848,849 AMOX 28:224 anti-microbial activity of 28:224 Amoxicillin 25:617;26:366 c-AMP phosphodiesterasc inhibitory activity 26:38 of dianchinenoside E and F 26:38 (+)-Ampelopsin A&B 26:551,566 Ampelopsin C&D 26:558,566 cis-Ampelopsin E 26:558,566 trans-Ampelopsin E 26:566 Ampelopsin E-H 26:558,567 Ampelopsis brevipedunculata 26:551 Ampelopsisjaponica 22:512 as anticonvulsive agent 22:512 Ampelosin 25:470 Amphetamine 25:537 as immunosuppressive drug 25:537 Amphetamine 25:537,538 Amphibia 21:3 Amphibian alkaloids 29:433 2,5-disubstituted decahydroquinolines as 29:433 from ants 29:433 from dart poison frogs 29:433 pharmacological activity of 29:433 strutural diversity of 29:433 synthesis of 29:433 Amphicarpa meridiana 23:273,275 Amphicarpeae edgeworthii 25:93 Amphidinium sp. 5:396,19:559 Amphidinolide M 19:566 cytotoxicity of 19:566
34 Amphidinolide Q 19:560 cytotoxicity of 19:560 Amphidinolides 5:396 Amphilectane-type diterpenoids 25:690 Amphimedon complanata 26:90 Amphimedon compressa 21:308 Amphimedon sp. 21:260;25:709,710; 26:454 Amphimedon sponge 26:74,88 Amphimedon terpenensis 21:350-352, 363,367 Amphimic acid A 26:88,89 Amphiphilic triterpenoids 25:541 Amphiscolops sp. 5:396 Amphotericin B 2:421,422,446; 4:513-520;6:261-306;10:150; 17:245 ;21:758;22:58,60,64,248; 26:794,795 Amphotericin B (AmB) 23:343,347,380 Amphoteronolide 10:153,166 Amphoteronolide B 4:573;6:261-276 Amphoteronolide B methyl ester 6:264, 265 Ampicillin 25:258 AMPK phosphorylates 25:525 Ampulliferine thunbergii 21:417 (-)-ampullicin from 21:417 (+)-isoampullicin from 21:417 Amsonia elliptica 1:125 Amti 23:657 Amycolatopsin sp. 28:150 Amygdala 30:375,376,379 effect on dorsal raphe serotonin (5-HT) neurons 30:376 Amylase 6:551,7:32-36,39;10:496-498; 8:343 ;24:995-998;25:719 enzymatic activity of 24:995-998 a-Amylase 7:32-35,10:242,243, 504-507,514,13:195;16:8622:622; 27:330,331 in aleurone protoplasts 27:331 13-Amylase 7:33,58,59,10:497;16:86 ~-Amylase inhibitor 13:189 acarbose as 13:189 Amyloglucosidase 7:13,10:567,357, 14:150 [3-Amyloid 30:837
Amylopectin 7:6,10:496-498 in starch 7:6 Amylose 5:288,291,292,7:6,10:496,497 Amylostatins GXGGG 10:509 inhibitory activity of 10:509 Amylostatins GXG 10:509 inhibitory activity of 10:509 Amylostatins GXGG 10:509 inhibitory activity of 10:509 Amylostatins XG 10:509 inhibitory activity of 10:509 synthesis of 10:507-511 Amylostatins XGG 10:509 inhibitory activity of 10:509 Amylostatins XGGG 10:509 inhibitory activity of 10:509 (x-Amyrenol 29:585 effect on CHY 29:585 effects on HIV- 1 protease 29:574 effects on collagenase 29:583 ~x-Amyrin (ot-amyrenol; viminalol) (ursane triterpene) 21:690;22:108, 119,121,129;23:824;27:589;29:574, 583,585 effects on collagenase 29:583 effect on CHY 29:585 effects on HIV- 1 protease 29:574 ~-Amyrin (ursene triterpene) 23:535, 546,824 ;25:58 ;29:574 ;30:719 effects on HIV- 1 protease 29:574 structure of 30:719 Amyrin 30:206 use in inflammatory skin conditions 30:206 (x-Amyrin acetate 27:589 c~-Amyrin linoleate 29:583 effects on collagenase 29:583 ~-Amyrin linoleate 9:461 (x-Amyrin linoleate ((x-amyrin cis-9.cis12-octadecadienoic acid ester) 29:583,585 effects on CHY 29:585 synthesized from c~-amyrin 29:583 [3-Amyrin palmitate 9:461
35 ot-Amyrin palmitate 29:583 effects on collagenase 29:583 synthesis from c~-amyrin 29:583 Amyris balsamifera 21:583 Anabaena circinalis 26:367 Anabaena cylindrica 25:717 Anabaena doliolum 26:366 Anabaena genera 27:879 Anabaena sp. 25:794;26:352,354,358, 359,364,365,378,379 Anabaena variabilis 26:366 Anabasine 21:51,97,110 Anabsin (guaine sesquiterpene dimer) 7:239;29:574 effects on HIV- 1 protease 29:574 Anabsinthin 7:239 Anabsinthin (guaine sesquiterpene dimer) 7:239;29:574 effects on HIV-1 protease 29:574 (15:0)-Anacardic acid (2-hydroxy-6pentadecyl benzoic acid) 9:314,316, 345,346,356 Anacardic acid 11 (Z)-diene 30:144 synthesis of 30:144 Anacardic acid 8(E)-monoene 30:143 by trans elimination reaction 30:143 Anacardic acid 8(Z)-diene 30:144 synthesis of 30:144 Anacardic acids 5:824-831 ;9:313,315, 316,328,330,331,333-341,346,349, 355,358,361-368,370,371 ;21:590, 591,592 ;24:297,298;30:147-148 synthesis of 30:147-148 Anacardic aldehyde 9:341 Anacardium giganteum 9:316 Anacardium occidentale 7:427,17:645; 9:75,316,318,323,329,332,335,337, 338,340,347;21:591 Anacardium semecarpus 9:318 Anacyclus 29:683 Anacyclus pyrethrum 10:162;21:378, 379;24:686,690,705,708, 710,712 anacyclin from 21:378 pellitorine from 10:162;21:378 Anaerobiosis 9:565,572 Anaesthetic activity 21:378
Anagallis arvensis L. 22:512 for epilepsy 22:512 Anagallis arvensis L. 22:512 for epilepsy and hysteria 22:512 Anagasta kueniella 9:322 Anagyrine 21:97 (-)-Anagyrine 26:487 Anagyrine 27:276 structure of 27:276 Anagyris foetida 27:278 Analeptic 30:72 Angelica keiskei use as 30:72 Analgesia 30:200,799,800,801 by 8-opioid receptor activation 30:801 by opioid 30:799 in mice 30:800 role of delta opioid receptor in 30:799 role of mu-opioid receptors in 30:799 Analgesic 17:633;30:193,194,204,799 alkaloid 30:799 use of Cannabis sativa L. as 30:194 use of Dispsacus asper as 30:204 use of Papaver somniferum as 30:193 Analgesic action 30:193 of olvanil 30:193 of ricinoleiic acid 30:193 of triphenyl phenol scutigeral 30:193 analgesic activites of 29:420 anesthetic activities of 29:420 antibiotic activities of 29:420 Analgesic activity 21:595,673 ;23:153, 180;26:32,56;30:195,198-201,817 ofbarbatosides A and B 26:56 of cembranes 23:180 ofdianosides A-1 26:32 of DPDPE 30:817 of enkephalyn 30:817 of kallilolides 23:180 of opioids 30:198-201 of pseudopterolides 23:180 ofpseudopterosins 23:153, 158,180
36 of secopseudopterosins 23:180 structure-activity relationships (SAR) 30:198 Analgesic alkaloid 30:799 addiction due to 30:799 for acute pain 30:799 gastrointestinal depression due to 30:799 respiratory depression due to 30:799 side effects of 30:799 tolerance due to 30:799 Analgesic characteristics 30:817 Analgesic drug 30:191,192,203 development of 30:192,203 use of 30:191 Analgesic effects 26:401,403,404,406, 416,418;30:205,208 by K + channel modulations 30:208 in thermal models of nociception 30:205 of furosin 30:208 of gallic acid 30:208 of geraniin 30:208 of Phyllanthus genus 30:208 of quercetin 30:208 of rutin 30:208 of stigmasterol 30:208 Analgesic mechanism 30:193 Analgesic potencies 30:800,813 ofopioid analogues 30:800,813 Analgesic properties 30:207 of menthol 30:207 Analgesics 30:191 in pain treatment 30:191 natural products as 30:191 Analgesics/antipyretics 30:192 acetaminophen as 30:192 dipyrone as 30:192 Analogs 27:336-337 conformational property of 27:337 Ananas comosus 27:872;29:600 Anandamide 30:195,196 as endogenous cannabinoid 30:195 effects on tetrahydrocannabinol 30:195
fluorine analogue of 30:196 pharmacological properties of 30:195 SAR of 30:196 Anandamide analogues 30:196 molecular field analysis of 30:196 Anandamide endocannabinoids 30:196198 structure of 30:197 Anaplastic carcinoma 26:712 Anas platyrhynchos 5:836 hemoglobin components of 5:836 Anaxagorea luzonensis 28:234 Anchinoe tenacior 25:862;28:715 Anchusa officinalis 17:126 Anchusa strigosa 29:571 Ancistrocerus antilope 5:223,232,253 Ancistrocerus campestris 5:224,252 Ancistrocerus sp. 5:251 Ancistrocladidine 20:408,433,434,437 Ancistrocladine 20,408,419,420,422, 423,431 Ancistrocladus abbreviatus 20:447 ancistrobrevin B from 20:447 Ancistrocladus alkaloids 20:408,437 Ancistrocladus heyneanus 26:813 Ancistrocladus korupensis 20:442,447; 26:822;27:865 korupensamines A and B 20:442 korupensamines C 20:447 michellamines from 20:442 Ancistrocline 20:408,424,425 Ancistrocongine 20:276 Ancorina sp. 28:120 Ancylostoma 26:481 Ancylostoma duodenale 26:425,429 Andalusol 25:249,250;29:102 activity in ACM bioassay system 29:102 activity in CRG bioassay system 29:102 activity in NFkB bioassay system 29:102 activity in NO bioassay system 29:102 activity in TPA bioassay system 29:102
37 Anderson & Bridgeman study 27:511 of proteinaceous polysaccharides 27:511 trans Anethole 27:16,33 structure of 27:33 Andrastins 24:452,453 FPTase inhibition by 24:403-464 Andrena haemorrhoa 19:129,131-132 Andrena ocreata 19:129 Andrena ovatula 19:129 Andrena wilkella 1:692;19:129 mandibular gland secretion 1:692 Andrimid 21:296 Androctonin 23:341 Androctonus australis 23:341 Androcymbium palaestinum 29:358 Andrographis paniculata 5:678,7:117, 17:472;24:275;25:251,270;29:102, 586-588 Andrographolide 29:102 activity in AOS bioassay system 29:102 activity in iNOS bioassay system 29:102 activity in NO bioassay system 29:102 Andropogon zizanioides 24:274 Androsace saxifragifolia 15:200 saxifragifolins A and B from 15:200 Androsaemum 30:609,610 Androst-l,4-diene-3,17-dione 9:411 Androst-4-ene-3,17-dione 9:15-17 Androstanolone 18:885 6,(5o0-Androstene-3,17-dione 8:188 Aneilema scapiflorum 22:512 for infantile convulsions 22:512 Anemarrhena asphodeloides 21:668, 670;24:919-922;26:237 ;28:234 in diabetic treatment 24:919 pseudoprototimosaponin AIII from 21:668 prototimosaponin AIII from 21:665 steroidal saponin from 21:670 Anemia mexicana 6:195,202,208 antheridiogens from 6:195,202, 208
Anemia phyllitidis 6:194,202 antheridiogen from 6:194,202 Anencephaly 23:571 Anethofuran 29:83 activity in GST assay system 29:83 Anethol 13:334-337 Anethole 21:599 trans-Anethole 5:473,13:332,15:29 Anethum graveolens L. 7:108,109; 27:379;29:83 Anethum sp. 29:581,582 Aneuploidogen diethylstilbestrol 26:271 ANF-activated membrane bound guanylate cyclase 25:523 Angelaud and Landais 29:467 carbaaldopyranoses synthesis by 29:467 Angelica archangelica 23:350 Angelica decursiva 23:352;27:835 Angelica furcijuga 25:471,476 Angelica gigas 27:835 Angelica keiskei 22:432,29:578,775; 30:55,56 from 22:4-hydroxyderricin chalcones from 30:56 inhibition of catecholamineinduced vasoconstriction by 30:55 use as analeptic 30:72 use as diuretic 30:72 use as lactagogue 30:72 use as laxative 30:72 use in catecholamine-induced vasoconstriction 30:72 use in coronary heart diseases 30:72 use in hypertension 30:72 xanthcangelel from 30:55 Angelica pubescens 26:436 Angelica shikokiana 27:429 Angelicin 22:539,522;23:337,338 Angeloyl oxyestafiatin 27:5778aAngeloylajadin 27:575 Angeloylcumambrin 27:577 Angeloylgomisin H 26:197,247 8c~-Angeloyloxy- 1[3-peroxy costunolide 27:560
38 8cx-Angeloyloxy-cosmnolide 20:471; 27:559 Angiogenesis 26:757;30:56,61-64 by fibroblast growth factor 30:56 by matrigel 30:56 effect of matrigel/VEGF/heparin mixture 30:61 effect of triterpenoids on 30:61, 62 in vivo 30:61 inhibition by carp oil 30:69 Angiogenesis inhibition 24:888-890 by magnosalin 24:888-890 Angiogenesis inhibitor 22:262 Angiogenesis inhibitory activity 24:406 Angiogenic response 30:61 role of heparin 30:61 Angiosperms 9:265 Angiostatic activity 21:435 AngiostrongTlus 26:484 Angiotensin II-induced hypertension 25:595 Angiotensin-II 26:267 Anguibactin 25:877 Anguillosporal 22:72 Anguillula aceti 26:450,452,459,464, 482 Anguina tritici 26:456 Angularly fused tricyclic framework 29:129 stTucmres with 29:128 Angulatin A 23:667 Angulatueoid G 23:667 Angusticraline 13:394 Angustiicine 1:36 Angustine 3:405,5:85,126 Angustone B 28:228 biological activity of 28:228 (-)-Anhalonine 2:163 2,7-Anhydro sugar analogue 30:463 14,15-Anhydro- 1,2-dihydrocapuronidine 5:125 1,6-Anhydro-2,4-di-O-benzyl-3-O(tertbutyl-di-methyl silyl)-[3-Dglucose 14:255 1,6-Anhydro-2-O-b enzoyl-3,4-di- Obenzyl-[3-D-galactopyranose 14:256
1,2-Anhydro-3,4:5,6-di- O-isopropylidene-D-mannitol 30:439 reaction of 30:439 2,3-Anhydro-4,6-O-benzylidene-~-Dtalopyranoside 14:167 1,6-Anhydro-4-deoxy-L-ribopyranose 14:255 2,3-Anhydro-allo-hexopyranoside 14:149 Anhydroalstonatine 1:125,126 Anhydroamarouciaxanthin B 6:151,152 Anhydroascorbic acid 4:718 Anhydroaustricin 7:236 14,15-Anhydrocapuronidine 5:125 2',3'-Anhydrocyclitol glycoside 14:147 Anhydrodeacyltautomycin 18:271,284 Anhydrodihydroartemisinin 22:154 Anhydrodimers 7:136,137 Anhydroerythromycin A 13:158 1,5-Anhydro-galactitol 7:65 1,6-Anhydro-galactose 7:65 Anhydrogrossmisin 7:236 Anhydromacrosalhine-methine 13:396, 397 l',6'-Anhydromaltose 10:507,510,511 l",6"-Anhydromaltotriose 10:507 Anhydroperoxisomicine-quinone-A ~ (T510) 22:570 Anhydrophlegamacine-9,10-quinone A2 22:580 Anhydrophlegamacine-9,10-quinone B2 22:580 E-Anhydropodorhizol 5:486 Anhydropodorhizol (nemorosin) 5:484488 Anhydroschumannificine 21:145 1,4-Anhydrosorbitol 12:29,30 16,17-Anhydrotacamine 5:126,9:179 Anhydrotaxininol 12:216 15(28)-Anhydrothyrisiferyl diacetate 5:363 Anhydroverlotorin-4c~,5 ~-epoxide 27:572 c~-3',4'-Anhydrovinblastine 27:780-783 c~-Anhydrovinblastine 27:782 Anhydrovinblastine Nb-oxide 14:812, 813
39 15'c~-hydroxyleurosidine from 14:812,813 15'-hydroxy-3'-oxoleurosidine from 14:812,813 5'-nor and 5',6'-seco derivatives of 14:872 3'-oxoanhydrovinblastime from 14:812,813 Polonovski reaction of 14:872 Anhydrovincristine 14:818,819 from anhydrovinblastine 14:818,819 Anhydrovobasindiol 5:123,9:171, 15:469 19(Z)-Anhydrovobasinediol 15:466, 467,491 3,4-Anhydro-cx-D-altropyranoside 14:170 1,6-Anhydro- [3,D-glucopyranose 6:287, 288 3,4-Anhydro-[3-D-galactopyranoside 14:170 1,6-Anhydro-[3-D-glucose 10:425 Aniba sp. 8:159 neolignans from 8:159 Aniba canellila 19:117 Aniba neolignans 8:159-163 Anigopreissin A 26:566 Anigozanthos sp. 17:372 Anilido 4:286 as protecting group 4:286 Anilidopiperidines 30:200 in central analgesic activity 30:200 8-Anilino- 1-naphthalenesulphonic acid 9:453 4-Anilinosampangine 23:6 Animal models with osteoporosis 30:499 effect of 1c~,25(OH)2D4 on 30:499 Animal product 24:904-916 effect on cardiovascular arrythmia 24:904 Animals 26:221 ;26:943 metastatic secondary tumor in 26:221
NO-mediated apoptosis in 26:943 Anion exchange 4:282,283 for oligonucleotide purification 4:283 in HPLC 4:282,283 Anion mediated alkylation 8:229 of difunctional acyclic terpenoids 8:229 Anion radicals 30:549 dimerisation of 30:549 [3,3]Anion radicals 30:549 dimerisation of 30:549 Anionic oxy-Claisen 12:93 Anionic oxy-Cope rearrangement 3:77, 78 eight-membered rings by 3:77,78 Anionic pinacol rearrangement 14:360 Anionic polysaccharide (PS) 30:401 Anisakis sp. 26:475 larvae of 26:457,474,475 Anisodine 21:56 Anisomycin 14:568 Di-p-Anisylmethylamine 12:152 Ankinomycin 11:136 Ankyrin 25:496 Annelation 19:227;24:203 ofresorcinol 19:227 of substituted phenol 19:227 regiospecific 19:227 Annelation reaction 14:694,695 Annelid worm 30:832 serine protease from 30:832 Annoba montana 26:212,243 syringaresinol from 26:212 (-)-syringaresinol from 26:243 Annona bullata 9:396,397;18:221 Annona densicoma 9:395 annonacin from 9:395 Annona glabra seeds 28:430 acetogenins from 28:430 against Dermatophagoides pteronyssinus 28:430 against Typhlodromus urticae 28:430 Annona muricata L. 17:277;18:213 22:512 for epilepsy convulsive seizures 22:512
40 Annona squamosa 9:398;28:404,415 extract of 28:415 Annonaceae 21:611;25:249 Annonaceous acetogenins 17:251-286; 28:437 as complex I inhibitor 28:436, 437 Annonacin 9:395,396;17:266,272,279; 26:441 tetraacetate of 26:441 Annonacin A 17:267 Annonacin- 10-one 17:272 Annonacinone 26:441 Annonaine 25:53 Annonidium monni 22:512 for epilepsy 22:512 Annonin 26:441 Annonin I 17:252 Annotinine 18:341 13,16-Annulated oxathiaphospholane 8:126,127 2[3,313-Annulated oxathiaphospholane 8:126,127 [4+ 1]-Annulation 3:40-45 triquinane synthesis by 3:40-45 [2+3]-Annulation 3:7 annulation methods 3:7 for five-membered rings 3:7 of aldehydes 3:5-58 triquinane synthesis by 3:47,48 [4+4]-Annulation 3:78 Danheiser version 3:78 for 8-membered ring synthesis 3:78-79 intermolecular 3:78 nickel catalysed intramolecular 3:78 Annulation 6:5 by Simmons-Smith reaction 6:5 intramolecular 10:407 of 1 methyl-2-tetralone 14:670,671 of c~-diazo-[3-keto ester 10:407 of cyclohexane ring system 6:5,6,29,30 of cyclopentane ring system 6:6-8,30,31 of enolate 10:414,415 of methylenecyclohexane 6:21,
22,53,54 ofpiperidone derivative 14:734 Rh (II)-mediated 10:407 Robinson annulation 6:17-21, 29,30 with 3-methylsilyl-3-butene-2one 10:414,415 Annulatophenonoside 30:624 Anochertus sedilloti 5:223-225,238,254 Anodic methoxylation 13:485,494 Anodic oxidation 7:161,163;8:159172;13:474,475,479 of c~-N-acetyl-~-N-tosy-L-lysine methyl ester 12:309,310 Anogeissinin 23:420 Anogeissus acuminata var. lanceolata 26:224 anolignan A & B from 26:224 Anogeissus latifolius 26:1157 Anogeissus sp. 26:1157 Anolignan A&B 26:224 HIV-1 RT inhibition by 26:224 Anolignan B 26:228,231 Anomalin 25:471,476 Anomalous metabolism 7:117 Anomalous ORD 2:160 Anomeric configurations 27:469,667 in aglycone 27:667 Anomeric deprotection 6:413-416 of disaccharide dipeptides 6:413-416 Anona spp. 28:392 Anonaine 21:84 (-)-Anonaine 24:857 hypotensive effect of 24:857 Anopheles 26:781,782 Anorexia 22:588;30:369 effect of circadian activity on 369 C15Ansa chain 23:54 C17Ansa chain 23:54 C23Ansa chain 23:54 CgAnsa chain 23:54 Ansa compounds 23:52 Ansachain 5:592 "Ansa-Chain" compounds 12:39 rifamycin S 12:37 rifamycin W 12:39 Ansamitocin 9:435;23:54 (P-3)-Ansamitocin 9:433,434
41 Ansamitocin P-0 23:71 P-3-Ansamitocins 23:71 P-4-Ansamitocins 23:71 Ansamycin 2:424,9:431-445,10:153; 23:51 ;24:545-546 antiviral microbial-derived compound 24:545-546 classification of 23:53,54 discovery of 23:53 Ansamycin antibiotics 23:51-106 antitumor activities of 23:96 biological properties of 23:93 cytotoxic activities of 23:96 Ansamycin lactams 10:149,150 Ansamycins 21:374,420,435,436,437; 23:79 biosynthesis of 23:79 Ansathiazin 23:54,61 Ansatrienin 23:54 Ansatrienin A 9:434 Ant repellant 6:142 neoxanthin as 6:142 Antagonism 21:601 ;26:240-245 of platelet activating factor (PAF) 26:240-245 6-Antagonist activity 30:810,811,817 against DEL antinociception 30:811 in vitro 30:818 of DTAOH 30:810,811 of DTOH 30:810,811 of 6-opioid receptor 30:818 Antagonist cannabinoid receptors 25:532 Antagonist effect 25:533;26:756 of dioxin 26:756 of oripainine 25:533 Antagonistic activity 20:515;21:233; 23:187;26:460,1065 Antagonistic alkaloids 21:4 Antagonists 21:52;22:16 ~c-Antagonists 30:807 Antedematose activities 21:633 Antemisin 25:349 Antharufin 25:543 Anthelmintic activity 1:408,5:552; 23:356;26:425,446,450,451,456,466, 476,478,481,482,487,491
ofpsoralen 23:356 Anthelmintic agents 12:3 Anthelmintics 26:426,431,444,465,478, 479,493;28:331,332 broad spectrum activity of 28:332 diminished activity of 28:331 Anthelvencins 5:552,553 Anthemidin 7:233 Anthemis nobilis 22:679 Anthemis saguramica 10:153,162 Antheraea polyphemus 22:387 (+)-Anthocerotonic acid 26:185 Anthocidaris crassispina 25:868 ganglioside GM5 from 18:486 Anthocyanidin 21:497;26:743,744,747, 748,770,771 Anthocyanidins 7:112,114,72322:421, 631-633;27:89328:275 cyanidin as 28:275 delphinidin as 28:275 malvidin as 28:275 pelargonidin as 28:275 structure of as 28:275 Anthocyanin pigments 23:773 Anthocyanins 5:646,647,658,7:192,723, 731,735;22:167,631,633;23:742; 25:513;26:305;28:275,276,277,292 cyanidin-3-glucoside as 28:275 delphinidin-3-glucoside as 28:275 for coronary heart disease 28:292 from black grapes 28:276 an blackberry 28:277 in blueberry 28:277 m cabbage, red 28:277 m cherry 28:277 in chokeberry 28:277 in cranberry 28:277 in currant (black) 28:277 m food plants 28:276 m grape (red) 28:277 m onion 28:277 in organe, blood (juice) 28:277 m raspberry, red 28:277 in strawberry 28:277 an wines, porto 28:277 in wines, red 28:277
42 malvidin-3-glucoside as 28:275 pelargonidin-3-glucoside as 28:275 Anthocyridin idB 25:616 Anthonomus grandis 1:693,7:187,190 Anthopleura elegantissima 2:306,9:493495 ;25:873 ;28:647 mycosporine-taurine from 28:647 Anthostoma avocetta 21:229 Anthoxanthum sp. 29:584 Anthozoa 23:153 Anthracenes 11:113,277 Anthracenone abscisic acid analog 27:331 Anthracnose fungi 9:228,230,240 Anthracophyllum archer 29:272 Anthracophyllum discolor 29:279 Anthracophyllum sp. 29:283 Anthracycline antibiotics 14:492; 21:157 antitumor activity of 14:492 Anthracycline prodrug 21:175 Anthracyclines 21:157,158,168 Anthracyclinone 4:318;21:162 biological activity of 4:318 cardiotoxicity of 4:318 Anthraflavic acid 25:543,544,541 Anthragallol 3-methylether 26:659 Anthragallol 26:657,659 2,3-dimethylether of 26:659 Anthramycin 23:256 Anthranilic acid 23:341 ;26:966,967, 969,970-972,1005,1008 Anthraquinone (alizarin) 26:629 Anthraquinone mitoxanthrone 14:21 Anthraquinone sulphonates 20:867 Anthraquinone-2,6-disulphonate 20:857 Anthraquinone-based PKA inhibitors 25:544 Anthraquinones 3:433,434;7:418-420, 427; 13:662,663 ;20:277 ;21:203,212; 22:557,572,575,597,617;25:509,513, 541 ;27:849;30:304,307 alizarin 25:541 anthrarufin 25:541 chrysazine 25:541 chrysophanic acid 25:541 emodin 25:541
from leguminoseae 30:304 from rubiaceae 30:304 purpurin 25:541 quinalizarin 25:541 quinizarin 25:541 structure-activity relationship (SAR) of 30:307 Anthraserpine 9:174 Anthricus sylvestris 18:555;26:215 anthricin from 18:555 deoxypodophyllotoxin from 26:215 (-)-deoxypodorhizone from 26:215 (-)-hinokinin from 26:215 nemerosin from 26:215 morelensin from 26:215 Anthrobacter citreus 20:234 Anthrobacter sialophilus 27:115 Anthrobacter simplex 20:234 Anthrobacter ureafaciens 16:87 Anthrotaxis spp. 3:456 Anti TNF-c~ antibody 25:461 Anti-addictive activity 21:95 Antiadrenergic alkaloids 21:102 Anti-AIDS activity 23:705 ofbetulinic acid 23:705 Anti-AIDS agent 11:267 (+)-castanospermine 11:267 Antiallergenic drug 26:759 Antiallergenic effects 12:398;26:264, 265 of K-252a 12:398 of staurosporine 12:398 Anti-allergic 30:71,72 baicalein as 30:71,72 Antiallergic activities 18:674;21:656, 657,659,594 ;23:364 ;26:759 of coumarin 23:335,356,357, 353,368,376,393,550,553 Antiallergic drugs 29:300 synthesis of 29:300 Antiallergic properties 21:660 Anti-angiogenesis 24:875 as biological action 24:875 Anti-angiogenesis action 24:875-925 of Kampo medicines 24:875-926 Antiangiogenic activity 21:437 Antiangiogenic agents 26:757
43 Antiangiogenic effects 30:63 ofganoderic acid F 30:63 Antianoxic activity 21:585 Anti-anxiety agent 26:413 Anti-apoptotic effects 28:175 Anti-arabic antibodies 29:543 Antiaris toxicaria 28:203,220 antiarone A from 28:203 antiarone B from 28:203 antiarone E from 28:204 antiarone J from 28:203 antiarone K from 28:203 ficusins A from 28:204 uses for arrow poison 28:203 Antiarone B 28:229 biological activity of 28:229 Antiarone F 28:229 biological activity of 28:229 Antiarone G 28:229 biological activity of 28:229 Antiarone H 28:229 biological activity of 28:229 Antiarone I 28:226,229 anti-human immunodeficiency virus (HIV) activity of 28:226 biological activity of 28:229 Antiarone J 28:229 biological activity of 28:229 Antiarrhythmic activity 23:356;30:200 of coumarin 23:335,356,357, 353,368,376,393,550,553 of loreainide 30:200 Anti-ARS2 antibody 25:435 Anti-arthritic agents 22:116 Anti-asthmatic activity 24:852 Antiatherosclerotic activity 23:355,468; 28:257,293 of organosulfar compounds 23:355,455-485 ofpolyphenols 28:257,293 Anti-bacterial 24:25 biological activity of 24:25 Antibacterial activities 5:512,747;10:78, 117;11:134;12:398;14:145;20:245, 712;21:21,108,109,190,207,213,214, 230,237,262,266,267,275,284,601, 615 ;23:41,126,164,235,258,355,468, 375,472,473,531,534,800;24:573,
856,857 ;26:226,1002;28:140,688; 30:328,738 of 1,2,3-trithiane 23:235 of 3',4'-dideoxykanamycin 14:145 of 5-methoxydehydrodiisoeugenol 26:226 of acteoside 5:512 of allicin 23:473 of allicin 23:473 of anonaine 24:856,857 ofbenz [a] anthracene antibiotics 11:134 of bicyclic phloeodictine B 28:688 of caryophyllene 23:535 of celastrol 5:747 ofcopalliferol A 23:534 ofcopalliferol B 23:534 of coumarin 23:335,353,356, 357,368,376,393,550,553 of curcmene derivatives 23:164 of curcumene derivatives 23:164 ofcurcumenes 23:180 ofcurcumenes 23:180 of dicoumarol 23:354,375 of dicoumarol 23:375 of dihydrodiisoeugenol 26:226 of distichol 23:535 of forsythiaside 5:512 of HA 26:1002 of Hypericum perforatum 30:628 of ikarugamycin 28:140 of ircenals 24:573 of isoeugenol 26:227 of kaempferol 23:535 of myricetin 23:535 of organosulfar compounds 23:355,455-485 of organosulfur compounds 23:355,468 ofphenylpropanoids 5:512 of resorcinols 30:158 ofresveratrol 23:531 ofresveratrol 23:74,531,534,746 of rhein 30:328 of saframycins 10:78 of SAM 23:41 of SAM MM1 23:41"
44 of sampangine metabolites 23:40 of sennosides 30:328 of sesquiterpenes 23:180 of sesquiterpenes 23:180 of staurosporine 12:398 of streptomycin 23:41 of streptormycin 23:41 of suspensaside 5:512 of teraxasterol 23:535 of tetrazomine 10:117 of thiosulfinates 23:472 of thiosulfinates 23:472 of toralactone 30:328 of trithiane 23:235 of urochordamine A 23:258 of urochordamine B 23:258 of (x-gurjunene 23:535 of ~-hydroxyacteoside 5:512 Antibacterial agent 5:377 aplasmomycin as 5:377 aurantinins as 5:601 chimeramycin as 5:613 Antibacterial effect 23:135 of [3-glucans 23:107,111,115,135 Antibacterial flavone 30:740 structure of 30:740 Antibacterial macrolide 5:613,747 Antibacterial metabolite 23:165 Antibacterial properties 30:628 against Staphylococcus aureus 30:628 Antibacteriophage activity 21:408 Antibiotic 24:799 biological activity of 24:799 Antibiotic activity 11:130;12:192; 17:283 ;21:188,202,223,239,364,437; 23:649;24:953-954;28:121 of 2-isocephems 12:192 of 2-iso-oxacephems 12:192 of celastroloids 23:649 of equisetin 28:121 of HIRE 24:951-954 ofmacrolide 17:283 of semivioxanthin 11:130 of thienamycin 12:188 Antibiotic potency 4:432 of imipenem 4:432
of 1-[3-methylthienamycin analogue 4:432 Antibiotic T-1384 5:549 Antibiotics 30:738 ansamycin 9:431-445 bio-organic chemistry of 9:431-445 biosynthesis of 11:207-213 from microorganisms 5:589 isoquinolinequinones 10: 77-145 mitomycin 9:431-445 relative configuration of 6:261 shikimic acid derived 11:182-191 sugar components of 11:213-222 Antibiotics A 26771 B 11:194 by Penicillium turbatum 11:194 Anti-bleeding activity 26:56 of Dianthus superbus var. longicalycinus 26:56 Antibodies 2:345-348;7:29;29:521, 529-532 active sites of 29:529 activity of 29:531 against carbohydrate containing antigens 29:521,536 against Streptomyces pyogenes 29:537 anti-BSA 29:532 anti-gum arabic 29:532 anti-lactose 29:532 antigen complex of 29:531 as vaccines 29:521 immunoglobulin classes of 29:521 in medicine 29:521 inhibition of 29:521,531 inhibition patterns of 29:536 inhibition via agar diffusion data 29:531 role in immunization 29:524 secretion of 29:525 Antibody dependent cell mediated cytotoxicity (ADCC) 25:273 Antibody dependent cellular cytotoxicity (ADCC) 27:803 Antibody directed enzyme prodrug therapy 21:157 natural anthracyclines for 21:157
45 Anti-CAM IgG 25:491,492 Anticancer activity 14:805;21:135,136; 23:335,356,357,353,368,376,393, 550,553;26:741,760,1060;27:807 Anticancer agent 14:805;19:511; 22:234;30:291 Scutellaria indica use as 30:291 Anticancer compounds 13:347-382; 14:805 Anti-cancer effects 23:475 ofallyl sufides 23:475 Anticancer peptide 27:799 Arg-D-Trp-NmetPhe-D-Trp-MetNH2 as 27:799 Anticancer treatment 14:805;26:162, 163 Anticandidal activity 20:485 Anti-carcinogenic activity 21:585; 22:345 ;28:257,293 ofpolyphenols 28:257,293 Anticaries activity 18:673 Anti-catarrhal activity 26:398 Anti-ChE activity 21:748 Anticholinergic 21:102 Anticholinergic agents 17:395 Anticholinesterase activity 22:30 Anticholinesterase alkaloid 21:744 Antichromonal action 22:625 Anti-CMV activity 30:404,405 ofSargassum horneri 30:405 of seaweeds 30:404 of sulphated polysaccharide (PS) 30:405 Anticoagulant activity 30:395,399,403 of coumarin 23:335,353,356, 357,3 68,376,393,550,553 ofheparin derivatives 30:399 ofpolysaccharide (PS) 30:395 of sulphated polysaccharides (PS) 30:403 Anticoagulation 30:838 mechanism of 30:838 Anti-coagulative principles 23:835 Anticoccidial activity 21:401 Anticoccidium agent 4:591 Anti-complement activity 22:136; 25:46;26:340 of serotonin agonists 25:46 of cyclic AMP-dependent protein
kinase 25:46 ofserotonin agonists 25:46 Anti-complementary 22:307 Anti-complementary activity of OG 25:17 Anticonvulsant 22:511,524,534 Afraegle paniculata as 22:511 Arisaema amurense var. serratum as 22:512 Asparagus recemosus as 22:513 Jatropha gossypifolia L. as 22:524 Jatropha multifida L. as 22:524 Lantana camara L. as 22:524 Tetrapleura tetraptera as 22:534 Anti-convulsant activity 24:858;28:176 of bilobalide 28:176 Anticonvulsant agent 22:511,512, 515-517,519,524,532,534 ;26:413 Afraegle paniculata as 22:511 Ampelopsisjaponica as 22:511 Boerhavia diffusa L. as 22:514 Clausena anisata as 22:517 Calliandra portoricensis as 22:515 Cinnamomum camphora as 22:516 Carum carvi L. as 22:515 Arisaema amurense var. serratum as 22:512 Calliandra portoricensis as 22:515 Carum carvi L. as 22:515 Cinnamomum camphora as 22:516 Clausena anista as 22:517 Daucus carota w. as 22:517 Jatropha gossypifolia L. as 22:524 Jatropha multifida L. as 22:524 Lantana camara L. as 22:524 Solanum dasyphyllum as 22:532 Solanum nigrum as 22:532 Tetrapleura tetraptera as 22:534 Anticonvulsive action 26:399 Anticonvulsive agent 22:512 Ampelopsisjaponica as 22:512 Anti-crocin mAb 25:957
46
Antidepressant 30:603,624,627 activity of hyperforin 30:627 activity of Hypericum perforatum as 30:624 use of hypericin as 30:624 use of Hypericum perforatum 30:627 Antidepressant drugs 21:101 Anti-depressant effects 28:177 of Ginkgo biloba L. 28:177 Antidepressant efficacy 30:335,626,627 chemical modification of 30:627 of Hyperici herb 30:335 of hypericin 30:626 Antidepressant-like effect 30:204,334 in forced swimming test 30:334 in mice 30:204 of Hyperici herb 30:334 of Siphocampylus verticillatus extract 30:204 Antidesmin A 406 Anti-dextran antibodies 29:538 of the IgG class 29:538 Anti-diabetic agents 7:47;30:340 quinonic derivatives as 30:340 Amidiarrheal activity 30:200 of loperamide 30:200 Anti-digoxin antibodies 15:374 Antidote 5:751 for scorpion sting 5:751 for snake bite 5:751 Antidote activity 22:460,462-482 Antidysenteric agent 5:758 Antiedema activity 12:384;22:443 of staurosporine 12:384 Antiemetic agent 24:900 gingerol as 24:900 Antiepileptic 22:516 Celastrus paniculta as 22:516 Withania somnifera L. as 22:535 Antiepileptic activity 22:516,517,532, 535 of Celastrus paniculata as 22:516 of Citrullus colocynthis as 22:517 of Solanum sodomaeum L. as 22:532
of Withania somnifera L. as 22:335 Antiepileptic agent 22:517,532 Citrullus colocynthis as 22:517 Solanum sodomaeum L. as 22:532 Antiepileptic drugs (AED) 22:507 Antiestrogenic activity 26:221 Antiestrogenic effects 26:209 Anti-exudative activity 22:97 Anti-fatty liver 30:94 action of Platycodi radix 30:94 Antifeedant 17:153,234,23724:845,866 bioassay of 24:866 biological activity 24:845 Antifeedant activity 2:277;10:425; 21:254,273,611,770;23:319,321, 341-344,348,666,670,671 ;24:101; 26:461,851 ;28:480;30:696 against insects 23:666 against mammals 28:480 of (-)-specionin 10:425 of 1-deoxy-2 [3,3[3-epoxynagilactone A 28:480 of allicin 23:341 ofamphotericin B 23:343 ofbombinins 23:341 ofbruceantin 23:321 of Celastrus angulatus 23:666 of chlorodimeform 23:319 of chlorodimeform 23:319 of cispentacin 23:344 of culmorin 23:344 of drosomysin 23:341 of griseofulvin 23:343 ofjaspamide 23:341 ofjuglone 23:342 ofleukotoxin 23:341,345 of majusculamide 23:344 ofnagilactone A 28:480 ofnagilactone C 28:480 of neoquassin 23:319 of nigakilactone E 23:319 ofPachyrrhizus erosus 24:779, 822-826 ofperoxyplakoric acid 23:341 ofpicrasin B 23:319,321 ofpradimicin A 23:343 of pristimerin 30:696
47 of quassin 23:319,321 of sesquiterpenes 23:670,671 of sinharine 23:343,348 of tannic acid 23:341 of tingenone 30:696 of tomatin 23:342 of xanthylletin 23:342 ofyadanziolide A 23:321 ofyurendide 23:341 Antifeedant assays 18:771-774 Antifeedant effect 26:853,861,863,871, 874,876 Antifeedant properties 22:234 Antifeedant sequiterpenes 23:668,669 from Elaeodendron buchananii 23:669 from Euonymusfortunei 23:668 from Euonymus bungeanus 23:668 of SAM 23:41 Antifeedants 7:395-397;29:129 polygodial as 29:129 warburganal as 29:129 Anti-fertility action 2:229-231 ofplumbagin 2:229-231 of Plumbago zeylanica 2:229, 231 ofisoshinanolone 2:229-231 Anti-fertility activity 5:754 antifertility activity of 21:759 antifungal activity of 21:758 ofpseudolaric acid B 21:759 Antifouling 17:93,98 Anti-fouling assay 21:36 Anti-fungal 24:25,799 biological activity of 24:25,799 Antifungal activities 21:186,192,197, 203,206,213,214,218,221,226,227, 233-235,223,238,240,389,391,399, 404,405,435,599-662 ;22:626;23:3,4, 271,341,344,348,468,473,798,801, 354,368 ;26:227,228,553,1098 ;28:4; 66,473,475,686;30:327,738,629 against Candida albicans 30:327,629 from Hypericum roeperanum 30:629 of (E)-8(17), 12-1abdadiene15,16-dial 23:798
of (E)-8b, 17-epoxylabd- 12-ene15,16-deol 23:798 of (E)-813,17-epoxylabol- 12-ene15,16-dial 23:798 of 2-hydroxynagilactone F 28:475 of 2-thioxopyrrolidines 26:1098 of 3,4,3 ',4'-tetramethoxylignan7-ol 26:228 of 3,5'-diallyl-2'-hydroxy-4methoxybiphenyl 24:861 of 3,5-Diiodetyramine 23:235 of 3-methoxysampangine 23:4 of 3-methylsampangine 23:9 of 4'-O-demethldehdropodophyllotoxin 26:227 of alga 5:342 of allicin 23:341,473 ofambigol A 23:342 ofamphotericin B 23:343 of aumulone 23:342 of Batzella sponge 28:685 of biphenyl ether,4,4'-diallyl-2,3'dihydroxybiphenyl ether 24:861 ofbombinins 23:341 ofbroussoflavonol G 28:4 ofbroussonin A 28:16 ofbroussonin B 28:16 of canaliculatol 23:534 of cardigone 23:342 of cispentacin 23:344 of coelenterate 5:342,368 of cordigol 7:408 of cordigone 7:408 of coumarin 23:335,356,357, 353,368,376,393,550,553 of culmorin 23:344 of discobahamin A 23:341 of drosomysin 23:341 of flavolol 3-methyl ether 7:414 of flavonoids 7:413 of garcigerrin 7:423 of glutionosone 23:343 of griseofulvin 23:343 of humulone 23:342 of hydroquinone uncinatone 7:408 ofintrapetacin A 28:66
48 of intrapetacin B 28:66 ofjaspamide 23:341 ofjuglone 23:342 of labdadiene- 15,16-dial 23:799 ofleukotoxin 23:341 of LL-Z1271c~ 28:473 of magnolol 24:861 of majusculamide 23:344 of mollusk 5:342 ofmyristic acid 23:348 ofnagilactone C 28:475 ofnagilactone E 28:475 of nanaomycins 11:127 of napthoxirenes 7:423;23:342 ofoidiodendrolide B 28:475 ofoidiolactone D 28:475 of ooponol 23:354 of organosulfar compounds 23:355,468 ofpapsorbic acid 23:342 o f Penstemon roseus 24:838 of peroxyplakoric acid 23:341 of polyoxins 23:343 ofpradimicin A 23:343 ofpseudolaric acid B 21:758 of pterocarpans 7:414 of pyrrolnitrin 23:344 of rhizocticin A 23:344 of SAM 23:41 of SAM MM1 23:41 of sampangine metabolites 23:3, 40 of sampangines 23:3,9,341 of semivioxanthin 11:130 of sesquiterpenes 2:287 of sinharine 23:343 of sponge 5:342,368 of streptomycin 23:41 of tannic acid 23:342 of thujaplicins 23:343 of tomtin 23:342 of tunicate 5:342 of urdamycin 11:134 of vaticaffinol 23:534 of vitamin A 23:271 of vitamin B 23:271 of vitamin B 23:271 of xanthones 7:410;30:629
of xanthyletin 23:341 of yurenolide 23:341 Antifungal activity evaluation 23:41 of SAM 23:41 of SAMMI 23:41 of SAMM2 23:41 of SAM MM1 23:41 of streptomycine 23:41 Antifungal agents 4:513;17:239;26:368; 24:406 Antifungal antibiotic 5:597,607,613; 21:388 cerulenin as 5:613 irumamycin as 5:597 phhoamycin as 5:607 Antifungal compounds 7:406,408,415; 23:13 Antifungal drug 23:3 sampangine as 23:3 Anti-fungal effects 23:481 of allyl sufides 23:481 Antifungal flavones 7:413 Anti-fungal green house 24:864 bioassay of 24:864 Anti-fungal holothurin 28:597 from Psolus patagonicus 28:597 Antifungal metabolites 21:187,190 from biological control fungi 21:187 Antifungal property 23:335-393 of coumarin 23:335,356,357,353 368,376,393,550,553 ;27:381 Antifungal pseudolaric acid B 21:754 Antifungal pyridone 21:213 Antigen 24:939 Antigen activation 30:592 induced by TPA 30:592 in Raji cells 30:592 Antigen modifications 29:533 by borohydride methods 29:533 by carbodiimide methods 29:533 by isoelectric focusing 29:533 by lipid isoelectric focusing 29:534 by monosaccharide oxidation 29:533 O-Antigen 6:262 from Salmonella anatum 6:262 synthesis of 6:262
49 Antigen preparation 29:528 from CNBr activated sepharose 29:528 of glycoconjugates 29:528 of glycoproteins 29:528 of immunoadsorbents 29:528 of microbes cell walls 29:528 Antigen-antibody reaction 21:659 Antigenic activity 26:1126 I-Antigenic determinant 10:483 O-Antigenic polysaccharide 14:236 from Pseudomonas aeruginosa 14:236 from Salmonella newington 14:233 from Shigella flexnert 14:233 Antigenic specificity 4:197 Antigenotoxic agent 26:271 I Antigens 10:457-461 II Antigens 10:457,461 Anti-glycemic effects 24:902-904 ofhumulones 24:902-904 Antiglycosuric activity 26:398 Anti-HeLa cell growth 21:695 Anti-Helicobacter pylori activities 28:234,241,243 of 6,8-diprenylorobol 28:243 of dihydrolicoisoflavone A 28:243 of formononetin 28:241 ofgancaonin I 28:243 ofgancaonol B 28:243 ofgancaonol C 28:243 ofglabrene 28:241 ofglabridin 28:241 ofglyasperin D 28:243 of glycyrin 28:243 of glycyrol 28:241 of glycyrrhetic acid 28:241 of glycyrrhizic acid 28:241 of isoglycyrol 28:241 of isolicoflavonol 28:243 of licochalcone A 28:241 oflicochalcone B 28:241 of licoisoflavone B 28:241 of licorice flavonoids 28:234 of licorice-saponin 28:241 of licoricidin 28:241 of licoricone 28:243
of liquiritigenin 28:241 of liquiritin 28:241 of 1-methoxyphaseollidin 28:243 of 3-O-methylglycyrol 28:243 of vestitol 28:243 Anti-hepatitis activity 21:662 Anti-hepatitis B agents 20:527 Antihepatitis sarmentosin 21:737 Antihepatotoxic 30.749 effects of apigenin 30:749 effects ofluteolin 30:749 effects of nepetin 30:749 effects ofquercetin 30:749 Antihepatotoxic activities 17:377; 21:651 ;26:256;27:660 Antihepatotoxic agents 26:255 3-deoxysilychristin 26:255 silandrin as 26:255 silchristin as 26:255 silybin as 26:255 silydianin as 26:255 silymonin as 26:255 Antihepatotoxic effect 23:479;25:99 ofallyl sufides 23:479 of OGs from Abri Herba 25:99 of OG 25:98,99 Antiherpes activity 5:565 Antiherpetic activity 21:718 Antiherpetic drug 30:400 acyclovir 30:400 complications of 30:400 Antihistaminic activity 30:200 of astemizole 30:200 Antihistaminic dispacamide C 25:870 Antihistaminic dispacamide D 25:870 Antihistaminic drugs 26:262 Anti-HIV activity 19:511,748;21:132, 133,149,252,269,664,665 ;23:316, 533,534,687,704 ;24:742,743 ;30:226, 396,397,399 activity of 30:399 of bergenin 23:535 of dibalanocarpol 23:535 ofMerremia peltata 30:397 of natural quassinoid glycosides 23:316,318 of balanocarpol 23:533,534 of neotripterifordin 23:687 oforthosphenic acid 23:704
50 of polyphenols 30:226 of potassium salt ofcaffeic acid tetramer 24:742,743 ofsalaspermic acid 23:704 of sodium salt of caffeic acid tetramer 24:742,743 of tripterifordin 23:687 Anti-HIV agents 24:742;30:227,397 aryltetralins 24:742 mechanism of action of 30:397 polyphenols as 227 Anti-HIV cytopathicity activity 30:399 of marine invertebrates 30:399 Anti-HIV flavonoids 28:226 2-arylbenzofuran as 28:226 from Glycyrrhiza species 28:226 from moraceous plants 28:226 AntiHIV licochalcone 21:740 Anti-HIV polysaccharide (PS) 30:399 from marine alga 30:399 Anti-HIV sulphated polysaccharide (PS) 30:399,400 from Ganoderma lucidum 30:400 from Lentimus edodes 30:400 natural sources of 30:399 Anti-HIV therapeutic agents 30:399 Anti-HIV triterpenes 21:664 Anti-HIV-assay 20:535,536 Anti-HIV-screening 13:665 Antihormones 20:515 Anti-HRP monoclonal antibodies 25:334 Anti-HSV activity 30:403 of fucan sulphates 30:403 of Leathesia difformis 30:403 ofSargassum horneri 30:403 Anti-HSV agents 30:401 Anti-HSV sulphated polysaccharide (PS) 30:403 from Ganoderma lucidum 30:403 Anti-HSV-1 activities 21:665,695,718 Anti-HSV-1 bioassay 21:698 Anti-human immunodeficiency virus (anti-HIV) 28:631 activity of Didemnum sp. 28:631,634
Anti-human immunodeficiency virus (HIV) activity 28:225,226 ofantiarone I 28:226 ofbroussoflavonol B 28:226 ofbroussoflavonol C 28:226 ofgancaonin R 28:226 ofglyasperin A 28:226 of glycyrol 28:226 ofkazinol B 28:226 of kumatakenin 28:226 ofkuwanon H 28:225 oflicochalcone B 28:226 ofmoracin C 28:226 of morusin 28:225 of mulberry tree 28:225 of norartocarpetin 28:226 of prenylflavones 28:225 of wighteone 28:226 Antihyaluronic activity 26:556 Anti-hyperanalgesic activity 30:201 of SDZ-249-665 30:201 Anti-hyperglycemic 24:875 as biological action 24:875 Anti-hyperglycemic action 24:875-925 of Kampo medicines 24:875-926 Antihyperglycemic activity 18:672; 19:351 Anti-hyperglycemic effect 24:902-904, 917-922 chemical structure of 24:916 of humulones 24:902-904 of isohumulones 24:902-904 of Morus spp. 24:917 of N-containing sugar 24:916-920 of timosaponin 24:919-922 Anti-hyperglycemic medicinal plants 24:916-920 Antihyperlipidaemic action 30:94,107 of chondroitin sulfate 30:107 of Platycodi radix 30:94 Anti-hypertensive activities 21:501 of Forsythia suspensa 5:513 of K-252a 12:398 of staurosporine 12:384 of suspensaside 5:513 Antihypertensive effects 26:235,236 Antihypoxic activity 18:373
51 Antihysteric 22:526 Muntingia calabura L. as 22:526 Antihysteric agent 22:526 Muntingia calabura L. as 22:526 Anti-i-antibody 10:480 Anti-IFN-?' 25:464 Anti-IL-1 antibody 25:464 Anti-IL-6 antibody 25:464 Antiinfective drugs 23:111 Antiinfective effect 23:135 of [3-glucans 23:107,111,115,135 Anti-infective plants 30:396 in traditional medicine 30:396 Anti-inflammation 24:875 as biological action 24:875 Anti-inflammation action 24:875-925; 30:72 of baicalein 30:72 of Kampo medicines 24:875-926 Anti-inflammatory 24:799,852,869 bioassay of 24:869 biological activity 24:25,799,845 effect ofshin-I 24:852 Anti-inflammatory activities 5:367; 13:647;17:137,376;18:775 ;21:130, 134,153,152,312,591,594,690,616, 656,657;22:93,119,307,345,361; 23:158,297,512,602,832;25:43; 26:340,341,343,391,398,400,401, 403,404,406,415,418,482,556,558, 741,759,1035;27:660,858;28:200, 257,293 ;671,844;30:206,207,224, 225,292,320,689,743 Copaifera riticulata for 22:360 cytotoxic activity 23:180 Heisteria pallida for 22:360 of 2-substituted 3-chloro- 1,4naphthoquinones 30:320 of 3',4-O-dimethylcedrusin 22:361 ofbroussoflavonol G 28:4 of californian sponge 28:671 of cembrones 23:180 of coumarin 23:335,356,357, 353,368,376,393,550,553 ofCurcuma comosa 26:884 of curcumenoids 23:835 of curcuminoids 23:835 ofDrymis winteri as 30:206
of genus Morus 28:200 of kallilolides 23:180 ofMorus nigra 30.'207 of phenolic triterpenes 30:689 ofpolyphenols 28:257,293; 30:224,225 ofProtium kleinii 30:206 of pseudopterolides 23:180 ofpseudopterosins 23:158,180 of saikosaponins 23:512 of Salvia desoleana 26:416 of samaderines 23:297 of Saponaria officinalis 26:27 of secopseudopterosins 23:180 of secosterols 23:168,180 of Sideritis javalambrensis 30:292 of Sideritis mugronensis 30:292 of sterols 25:43 of Tripterygium wilfordii 30:689 of triterpenes 30:689 of triterpenoids 25:43 Anti-inflammatory agent 5:753;7:397, 14:315 ;21:616;24:898;26:32 aconitine as 24:898 barbatoside A as 26:56 barbatoside B as 26:56 from Dianthus barbatus 26:32,56 Anti-inflammatory diterpenoids 23:688 Antiinflammatory drug 17:130;23:111 Anti-inflammatory effect 26:262,263, 264;30:206 of feverfew 30:206 of K-252a 12:398 of parthenolide 30:206 of staurosporine 12:398 Anti-inflammatory inhibitor 23:175 Anti-inflammatory reactions 30:72 Anti-influenza activity 30:407,408 of Cochlodinium polykrikoides 30:408 of Crenomytilus grayanus 30:408 of Nothogeniafastigiata 30:408 of Pinus parviflora 30:407 ofSpirulina platensis 30:408 of Ulva lactuca 30:408 Antijuvenile hormones 22:395
52
Anti-lactose antibodies 29:538 Antileishmanial activity 21:674,744; 26:229,790,813,887,789,790,791, 800,805,807,810,811,821,828,830; 30:742 of Baccharis dracunculifolia 30:742 of Baccharis genistelloides 30:742 ofBaccharis incarum 30:742 of Baccharis pentlandii D.C. 742 ofBaccharis salicifolia 30:742 ofBaccharis tricuneata 30:742 of genus Baccharis 30:742 of lignans 26:229,790,813,887 in vitro 30.'742 Antileukemic activity 1:305;4:232; 7:382-387,390;17:348;23:70,285, 490,649;24:573 of ansamitocin P-3 23:71 of asperdiol 23:490 of bisbrusatolylglutarate 23:305 of bisbrusatolylmalonate 23:304 ofbruceanol A 23:313,288 ofbruceanol B 23:313,288 ofbrusatol 23:304 ofbrusatolyl esters 23:304 of diterpene triepoxides 23:649 of gnidimacrin 23:490 of ircenals 24:573 ofjatrophone 23:400,490 of natural maytansinoids 23:70 of semisynthetic maytansinoids 23:70 Antileukemic P388 activities 21:770 Amileukemic principle 23:70 Antileukoderma 23:356 methoxsalen 23:356 Antileukoderma activity 23:356 of methoxsalen 23:356 Antilipoperoxidant 22:307;30:223 Anti-malarial activity 7:391-393,424; 21:346;23:301,838;24:282;26:779, 1036 of 3-geranyloxy-6-methyl- 1,8dihydroxyanthrone 7:424 o f 3-geranyloxy- 6-methyl- 1,8dihydroxy anthraquinone 7:424 of acetylvismione D 7:424
of amarolide 23:301 of artemisinin 7:424 of chaparrin 23:301 of chaparrinone 23:301 of chloroquine 23:301 of Cinchona succiruba 26:779 of glaucarubolone 23:301 of holacanthone 23:301 of quassinoids 7:391-394; 23:285-333 of quinine 7:424 ofvismione D 7:20 Anti-malarial agents 8:391-394,351; 20:516-521 ;30:330 against chloroquine-sensitive (T9-96) 30:330 Antimalarial assay 30:596 in vivo 30.596 of alkaloids 30:596 Antimalarial compounds 22:145 Antimalarial drugs 25:327,360;26:1035; 30:595 as chemosensitizers 30:595 as resistance-modifiers 30:595 chloroquine sensitivity in 30:595 Antimalarial effects 30:561,588,595, 597 of Hernandia moerenhoutiana 30:561 of Hernandia voyronii 30.561, 577 ofHernandia sp. 30:588 ofhervelines A-D 30:595 of laudanosine 30:595 of reticuline 30:595 Antimalarial naphthoquinones 30:330 atovaquone 30:330 Antimalarial therapies 25:361 Anti-metastatic activity 28:559;30:56, 58,59,60,64,69,152,292,329,628,629, 738 against Bacillus subtilus 30:293 against gram-positive bacteria 30:629 against Klebsiella pneumonia 30:293 against Staphylococcus aureus 30:293,329 against Staphylococcus
53
epidermidis 30:293 chemical instability 30:628 from Ganoderma lucidum 30:58 from Hypericum perforatum 30:628 from Hypericum japonicum 30:629 from medicinal plants 30:738 from novoimanine 30:628 in mice 30:59 of carp oil 30:56,64,69 of flavonoid 30:292 of Ganoderma lucidum 30:60 of Ginkgo biloba 30:152 of hyperforin 30:628 of natural products 28:559 of triterpenoids 30:58 of phloroglucinol derivatives 30:629 uses in folk medicine 30:738 Antimetastatic agents 19:351 Antimetastatic effect 16:93;25:441 on CVS 25:441 Antimetastic immunity 25:429 Anti-microbial 24:863-864 biological activity 24:799 bioassay of 24:863-864 Anti-microbial action 24:112 Anti-microbial activity 5:752;10:443; 15:327-339;18:776-778;21:153, 235,257,401,571,573,591,596,597, 599,606;22:626;23:94,153,180,233, 237,249,262,268,267,346,353,522; 24:64,69,206,330,331-334,402,403, 404,406,417,418,443,470,485,859, 1091,1092,1189;26:64,330,401,402, 1189;27:807;28:62,224,257,293,698, 671 against Candida albicans 5:752 against Clostridium difficile 5:601 against Clostridium perfringens 5:601 against gram-positive bacteria 23:94 against Proteus mirabilis 5:752 against Proteus vulgar& 5:752 against Staphylococcus aureus 5:752
of (-)-acetomycin 10:443 of 13-methylpentadecanoic acid 26:64 of phenylethanoids 26:330 of 3-O-methylglycyrol 28:224 of 3 [3-O-cis-p-coumaroyl alphitolic acid 28:62 of 3[3-O-cis-p-coumaroyl maslinic acid 28:62 of 3 [3-O-trans-p-coumaroyl alphitolic acid 28:62 of 3 [3-O-trans-p-coumaroyl maslinic acid 28:62 ofalphitolic acid 28:62 of AMOX 28:224 of amphibian venoms 15:327-339 ofbetulinic acid 28:62 of californian sponge 28:671 of coumarin 23:335,356,357, 353,368,376,393,550,553 of cryptolepine 5:752 of cyclocolorenone 24:859 of defensins 23:346 of dimer triterpenes 18:776-778 of dithiocarbonates 26:1091, 1092 of essential oil 21:571,596 ofeudistomin U 23:267 of eudistomins 23:233,262,268 of formononetin 28:224 of Fraxinus ornus 26:334 ofgancaonin I 28:224 ofgancaonol B 28:224 of glabrene 28:224 of glabridin 28:224 ofglyasperin D 28:224 of glycyrin 28:224 of glycyrol 28:224 ofhalistanol sulfate 28:698 of HMPT 26:1091,1092 of hydroxycoumarins 26:330 of isoglycyrol 28:224 of isolicoflavonol 28:224 of lamellarins 23:249 of Licania heteromorpha vat. heteromorpha 28:62 oflicochalcone A 28:224
54 of licochalcone B 28:224 of licoisoflavone B 28:224 of licorice flavonoids 28:224 of licoricidine 28:224 of licoricone 28:224 of liquiritigenin 28:224 of liquiritin 28:224 of medrrhodine A and B 5:618 of MMTP 26:1091,1092 of MTBI 26:1091,1092 ofpolyphenols 28:257,293 ofpseudopterosins 23:153,158 of Salvia officinalis 26:402 of Salvia sclarea oil 26:401 of secoiridoids 26:330 of secopseudopterosins 23:180 of sesquiterpenes 2:287,288 of theonellapeptolides 26:1189 of triterpenes 18:776-778 of tyramine 23:237 of verbascoside 23:522 of vesititol 28:224 Antimicrobial agent 5:753 Antimicrobial alkaloids 21:109 Antimicrobial consitituents 21:607 Antimicrobial peptide 22:83 Antimicrobial properties 27:378 Antimicrosporidial activity 26:458 Anti-migrane principle 24:849 in Tanacetum parthenium 24:849 Antimitotic activity 5:461 ;23:359,376; 30:224 of coumarin 23:335,356,357, 353,368,376,393,550,553 of gigantecin 9:396 of lignans 5:461 ofpolyphenols 30:224 Antimitotic agent 22:482;30:5 discodermolide as 30:5 Antimitotic inhibitory activity 24:406 of combretastatin A-4 24:406 Anti-mu stimulation 25:272 Anti-mutagen 24:851 Antimutagenic 21:641 Antimutagenic activity 21:583,584,585, 616,641,642 ;23:107 ;26:1099,1100; 30:315-317,765
of [3-glucans 23:107 of chlorophyllin 30:765 of quinones 30:315-317 Antimutagenic agent 22:307 Anti-mutagenic effects 23:478;26:510 ofallyl sufides 23:478 Antimycine A 16:694 antifungal agent 16:694 Antimycobacterial activity 23:4,9 of 3-methylsampangine 23:9 of sampangines 23:9 Antimycoplasmal activity 11:127 ofnanaomycins 11:127 Antimycotic activity 22:70,81 ;23:4 Antimycotic/antimycobacterial activity evaluation of 23:4 3-methoxysampangine 23:4 Antinematodal activity 26:425,433, 456,457,464,472,483,484,488,494 Antinematodal agents 26:456 Antinematodal effect 26:481 Antineoplasic activity 21:389;28:470 against P 388 cells 28:470 Anti-neoplasmic activity 27:378,386 Anti-neoplastic activity 4:29;22:248, 558;24:309-318;30:732 of plants 30:732 Antineoplastic agent 28:145,648-49 dolastatin 3 as 28:648 dolastatin 10 as 28:145,649 Antineoplastic drugs 26:158,169,214, 799,825 Antineoplastic glycoproteins 7:285 Antinociception 30:204,802,805 in vivo 30:805 inhibition by opioid receptor antagonist 30:204 monoamine-synthesis inhibitor 30:204 Antinociception action 30:201,204,205, 206,207,800,804,814,815,816 by GABAergic receptor 30:204 by intracerebroventricular 30:814 by noradrenergic receptor 30:204 by serotonergic receptor 30:204 in capsaicin model of pain 30:205
55 in mice 30:814,816 in neonate rats 30:206 in rats 30:814 in vitro 30:804 in vivo 30:207 mechanism of 30:205 of (-)-menthol 30:207 of (+)-allomatrine 30:205 of (+)-matrine 30:205 of biflavonoids 30:207 of cannabinoids 30:194 of cis-8,10-di-N-propyllobelidiol hydrochloride dihydrate (DPHD) 30:204 of DEL 30:800 ofDEL C analogues 30:815 ofdeltorphin B 30:804 of DER 30:800 of dispsacus saponin C 30:204 of drimanial 30:206 of glycopeptides 30:816 of hodgkinsin 30:205 of kalopanaxsaponins-A 30:203 of kalopanaxsaponins-I 30:203 of morusin 30:207 of naltrindole 30:816 of piperidine alkaloid hydrochloride 30:204 ofprenylflavonoid 30:207 ofProtium kleinii 30:206 ofRheedia gardneriana 30:207 of SDZ-249-665 30:201 of Siphocampylus verticillatus extract 30:204 oftormentic acid 30:207 via glutamate NMDA receptors 30:205 Antinociceptive activity 21:591 Antinociceptive agent 30:205 incarvillateine as 30:205 Antinociceptive properties 30:206 ofDrymis winteri 30:206 Anti-obesity 30:79,88,94 action of 30:94 action of saponin 30:94 effects of 30:79 mechanism of 30:88 natural products as 30:79
Anti-obesity action 27:398,400,402,403 of chitosan 27:402,403 of natural products 27:398 ofodong tea 27:400 of soyasaponins 27:398 Anti-obesity activity 30:88 of Platycodi radix 30:88 Anti-obesity effector 30:80,82 from oolong tea 30:82 Anti-obesity effects 30:86,100 in high-fat diet-treated mice 30:86,101 inhibitory actions of 30:86 of chitin-chitosan 30:100 ofoolong tea 30:86 Anti-orientation 14:753 Antioxidant 4:495;9:371,372;21:618; 23:771 ;24:845,868 ;30:524,744 bioassay of 24:868 biological activity 24:845 garlic acid as 23:771 protective functions of 30:744 vitamin C (ascorbic acid) 30:524 vitamin E (tocopherol, TOH) as 30:524 Antioxidant activities 21:599,600,618; 22:308,321,345;23:395,534,535,742, 772,773,845 ;25:59;26:250,255,509,5 56,672,763,768,887,1005,1006;28:4, 16,17,63,179,257,293,773 ;30:173, 224,225,289,320,321,524,561,743, 745 of c~-tocopherol 26:1006 of 3-hydroxycoumarins 30:225 of 8-hydroxy-naringenin 28:64 of alizarin 26:672 ofanthocyanin pigments 23:773 of anthraquinones 30:320 of apigenin 23:742,748 of baicalein 30:289 of baicalin 30:289 ofbroussoaurone A 28:16,17 ofbroussoflavan A 28:16 ofbroussoflavonol F 28:17 ofbroussoflavonol G 28:4,17 of carotenoids 30:524 ofcassumunin A 23:845 ofcassumunin B 23:845 ofcassumunin C 23:845
56
of C-glycosylflavones 23:772 of chrysoeriol 23:742 of cyanidin 23:536,551,742,748 of diosmetin 23:742 of epigallocatechin 23:772 of epigallocatechin gallate 23:742,770,772 of flavonoids 26:765 of garlic 23:771 of Ginkgo biloba L. 28:179 of herbal drugs 25:44 of Hernandia moerenhoutiana 30.'561 of Hernandia voyronii 30.561 of isoorhamnetin 23:742 of isorhamnetin 23:748 of kaempferol 23:742 of kaempferol 3-O-(2"-[3-Dxylopyranosyl)-c~-Lrhamnopyranoside 28:64,65 of kaempferol 3-O-c~-Lrhamnopyranoside 28:64 of Licania licaniaeflora 28:63 of lignans 23:773 of luteolin 23:742,772 of malvidin 23:742 of menadione 30:321 of myricetin 23:742 of natural flavonol 30:224 ofoleanolic acid 23:535 of orcinol 30:173 of peonidin 23:742 of petunidin 23:742 ofphylloquinone 30:321 ofpolyphenol derivatives 30:224 of polyphenols 23:773;28:257, 293;30:224 ofpropylgallate 23:772 of quercetin 23:742 of quercetin 3-O-c~-Larabinopyranoside 28:64 of quercetin 3-O-a-Lrhamnopyranoside 28:64,65 of quercetin 3-O-f3-Dgalactopyranoside 28:64 of quercetin-3-O-ot-Lrhamnopyranoside 28:64 ofresveratrol of 23:534
of synthetic pharmacological agents 30:224 of tannic acid 23:395 of tannins 23:442 of taxifolin 3-O-cx-Lrhamnopyranoside 28:64 of ubiquinone 30:321 of wogonin 30:289 Antioxidant anthocyanidins 23:742 Antioxidant flavan-3-ols 23:743 structures of 23:743 Antioxidant flavonols 23:742 Antioxidant hydroxycinnamic acid 23:744 structures of 23:744 Antioxidant hydroxycinnamic acid 23:744 structures of 23:744 Antioxidant phenolic metabolites 23:739-795 biosynthesis of 23:740 changes during postharvest storage 23:739-795 changes during processing 23:739-795 from fruits 23:739-795 from vegetables 23:739-795 general structures of 23:740 Antioxidant properties 23:739;25:919, 930,935 of flavonoids 23:739 in apples 745 in apricot 23:745 m cherry 23:746 in citrus 23:747 m grapefruit 23:747 m grapes 23:748 in lemon 23:747 in olive 23:749 m orange 23:747 in peach 23:749 in pear 23:750 in plums 23:750 in raspberry 23:750 in strawberry 23:752 Antioxidative activity 23:342 of tannic acid 23:342 Antiparasitic activity 23:359,473; 26:800,817,819
57
of allicin 23:473 of coumarin 23:335,356,357, 353,368,376,393,550,553 with chalcones 26:800 Antiparasitic properties 30:741 family compositae 30:741 Anti-pathogenic phytoalexin compounds 25:652 Anti-peptide ulcer effect 25:430 of Chlorella vulgaris strain CK 22 (CVs) 25:430 Antiperiplanar orientation 14:457 Antiperoxidative effects 26:249-255 of lignans 26:249-255 Antiperspirant 26:398 Antiphlogistic 17:451 Antiphlogistic activities 21:633 Antiphlogistic drugs 22:114 Antiplamsodial naphthylisoquinoline 26:822 Antiplaque activity 21:613 Antiplasmodial activity 19:587; 26:788-800,805,806,808,810,813, 815,822-824,1035 ;30:596,597 in vitro 30:596,597 of chloroquine 30:596 of dioncopeltine B 26:822,823 ofdioncopeltine A 26:822,823 ofhervelines A-D 30:596 ofisoquinoline alkaloids 30:597 of laudanosine 30:596 of lignans 30:597 of reticuline 30:596 Antiplasmodial agents 20:525 Antiplasmodial flavonoids 26:801 Antiplasmodial phloroglucinol 26:797, 798 Antiplasmodic activity 21:584,614 Antiplatelet activity 23:364;30:594 of coumarin 23:335,356,357, 353,3 68,376,393,550,553 induced by PAF 30:594 of furofuran lignans 30:594 Anti-platelet aggregation activity 24:741 Antiplatelet aggregation effect 30:593, 597
in vitro 30:597 ofisoquinoline alkaloids 30:597 of lignans 30:597 Antiplatelet aggregation mrbidimetry assay 30:594 activity of Hernandia species in 30:594 activity of lignans in 30:594 in vitro 30:594 Anti-polio virus activity 30:411 of seaweeds 30:411 of Trichilia glabra 30:411 Antipredation 17:93 Anti-progression activity 30:593 Anti-proliferation 24:875 as biological action 24:875 Anti-proliferation action 24:875-925 of Kampo medicines 24:875-926 Anti-proliferation effect 30:313,495 against L1210 cells 30:313 of lc~,25(OH)zD 30:495 Anti-proliferative activity 7:419,422, 245,515;16:93 ;21:312;23:168; 23:168,180;26:485;28:17,145 ofbroussoflavonol F 28:17 ofbroussoflavonol G 28:17 ofdolastatin 10 28:145,649 of secosterols 23:168,180 Antiproliferative agent 23:472 Antiproliferative effect 12:393;23:361; 26:752;27:802,862 against HL-60 cells 12:393 against T cells 12:393 against BALB/C mouse 3T3 cells 12:393 against bovine brain cortex capillary 12:393 in Walker rat carcinoma cell 12:390 LzCB lymphocytes 12:393 mouse isolated microglia 12:393 NIH/3T3 fibroblasts 12:393 of 8-methoxypsoralen (8-MOP) 23:361 ofanticancer drug 12:390 ofcis platin 12:390 of endothelial cells 12:393 of human breast cancer 2R-75 cells 12:393
58 of human myeloid progenitor cells 12:393 of staurosporine 12:393 Antiprotozaol labdanes 26:810 Antiprotozoal activity 21:435 ;23:473; 26:452,780,795,797,798,810,825, 1060 of allicin 23:473 of sesquiterpenes 26:807 Antiprotozoal agent 26:230 (+)-nyasol as 26:230,231 Antiprotozoal anthraquinones 26:805 Antiprotozoal drugs 26:793 Antiprotozoal isoquinloines 26:821 from Annonaceae 26:821 from Berberidaceae 26:821 from Hernandiaceae 26:821 from Menispaermaceae 26:821 Antipsoriatic activity 30:323 against growth of human keratinocytes 30:323 of quinonic compounds 30:323 Anti-psychotic activity 24:1116 of selected natural products 24:1116 Antipyretic 30:825 properties of earthworm 30:825 Anti-pyretic action 24:55 Antipyretic activity 18:775;21:591; 26:1035;28:200 of genus Morus 28:200 Antiquorin 9:280 Antirachitic activity 30:484 of vitamin D analogues 30:484 Antirachitic factors 17:623 Anti-radical activity 28:257,293 ofpolyphenols 28:257,293 Anti-retroviral drugs 24:487,488 Anti-retroviral efficacy 30:628 by inhibition of protein-kinase Cmediated phosphorylation 30:628 of hypercin 30:628 Antirheumatic agent 30:292 Sideritis javalambrensis as 30:292 Anti-rheumatoidal effect 30:204 of hederaginin monodesmodides 30:204
Antirride 7:465,466 Antirrinoside 7:455,477 Anti-rubella activity 30:409 of dextran sulphate 30:409 of scleroglucan 30:409 of sulphate derivatives 30:409 Anti-secretory activity 24:799 biological activity 24:799 Anti-seizure activity 24:1111,1112 of selected natural products 24:1111,1112 Antiseptic agent 23:642 teucrium sp. as 23:642 Antiseptic lotion 30:159 resorcinolic lipids used as 30:159 Antiseptic-disinfectant 26:398 Antisera 15:368 Anti-serotonergic activity 24:799 Anti-sigs and anti CD40 25:272 Antispasmodic 22:346,525 Achyrocline satureioides as 22:346 Limnophila chinensis as 22:525 Antispasmodic activity 28:4,670 ofAgelas nakamurai 28:670 ofbroussoflavonol G 28:4 Antispasmodic agent 22:346,525 Achyrocline satureioides as 22:346 Limnophila chinensis as 22:525 Antispasmogenic activity 26:239 Antispasmolytic activity 23:544,591 Anti-stress activity 20:646 Anti-stress effects 28:177 of Ginkgo biloba L. 28:177 Antisweet activity 18:671,672 of gymnemic acid 18:671,672 Anti-thrombic action 30:70 of flavonoids 30:70 Antithrombogenic 30:841 role in EFE-immobilized polyurethane surface 30:841 Antithrombogenicity 30:841 Antithrombotic action 30:289,840 of baicalein 30:289 of baicalin 30:289 oflyophilized powder 30:840 Anti-tick activity 21:621
59 Anti-TNF- a 25:464 Anti-TNFa-antibodies 25:461 Anti-tobacco mosaic virus activity 23:73 Antitopoisomerase II 25:693 Anti-trichromonal agent 22:617 Antitrypanosomal activity (Trypanusosma cruzO 26:792 Anti-tubercluosis activity 20:712; 23:318 of natural quassinoid glycosides 23:318 Anti-tubercular activity 5:752,753 Anti-tubercular agents 5:751 Antitumor 30:69,160 extract of earthworm as 30:840 mechanisms of 30:69 Antitumor activity 1:275,316-320-408; 17:17;21:137,405,420,435,436,638, 704,733;22:676;23:74,96,126,132, 139,395,445,522,696,721; 24:272-275,288,845,847,849; 25:43,430,431,438,450-453;26:56, 482,706;27:803;28:211,517,519,559, 560,566 ;30:3,28,29,55,56,58,59,64, 65,224,314,395,589,690,777,840,841 against intraperitoneally (ip) inoculated leukemia 23:74 antitumor activity of 21:733 discodermolide as 30:3 in mice 30:160 in rumor-bearing animals 30:59 in vivo 30:28 of (-)-acetomycin 10:444,447 of (+)-5-epi-acetomycin 10:447 of acronycine 13:365-382 of ansamycin antibiotic 23:96 of ARS2 25:435,451 of benz[a] anthracene antibiotics 11:134 of carp oil 28:566;30:64,65 of celastraceae 30:690 of chitosan 28:560 of Chlorella vulgaris 25.'430, 431,450,452,453 of Chlorella vulgaris strain CK 30:777 of Coley's toxin 28:519 of cyanocycline A 10:103
of Dianthus superbus var. longicalycinus 26:56 of didemnins 10:254-257 of diphyllin 5:462 of fish oils 28:566 of fucoidan 30:56 of Ganoderman lucidum 30:58,59 of geldanamycin 23:96 of glycoprotein 30:841 of glycoprotein-rich substance 30:777 of glycosylated component 30:841 of glyfoline 13:375-380 of Hernandia species 30:589 of Hypericum genus 30:314 of indolo [2,3-a] carbazole alkaloids 12:390-396 of ingenol type diterpenes 24:288 of K-252a 12:394,395 oflignans 5:461 of lipids 28:517 of Magnolia officinalis 24:849 ofmaytansinoids 23:721 of morusin 28:211 of naphthocyanidine 1O:104 of natural products 28:559; 30:55,56 of neolignans 24:845,847,849 of nogalamycin 4:335 ofoleic acid 30:56 of pironetin 30:29 of Podophyllum 26:210 ofpolyphenols 30:224 ofpolysaccharide (PS) 30:395 o f pristimerin 5:747 of protein-bound [3-glucan 23:132 of quinocarcin 10:117 of rebeccamycin 12:394 of regelide 23:696 of regelin 23:696 of regelinol 23:696 of saframycins 10:78 of staurosporine 5:275; 12:390-394 of sterols 25:43
60 of tannic acid 23:395,445 of taxol 12:180 of tetrazomine 10:117 of triterpenoids 25:43;30:58,59 of triterpenoids in mice 30:59 of tubeimoside 21:733 oftubeimoside I 21:733 of tuna oil 28:566 ofUCN-01, UCN-02 12:395 of urdamycin 11:134 of verbascoside 23:522 of wilforlide 23:696 pironetin as 30:3 Anti-tumor agent 1:180,268,269;3:301, 383 ;9:383,385 ;23:829;24:1055,1085 Antitumor and/or antimetastatic activity 30:67 of carp oil effects on 30:66 of oleic acid effects on 30:67 Antitumor antibiotic 1:498-7215:592, 593;19:118 Antitumor bioactivity 30:841 from earthworm 30:841 Antitumor bioassay 9:383,386,401 Antitumor bisbolan sesquiterpenes 23:830 [3-atlantone 23:830 ~x-curcumene 23:830 r-turmerone 23:830 xanthorrhizol 23:830 Anti-tumor clerodane diterpenes 24:280-282 Anti-tumor compounds 24:269-350 Antitumor drugs 30:164 therapeutic action of 30:164 Antitumor effect 23: 107,115,123,126; 25:440;27:439 of carp extract 27:439 of glucan 23:107,115,123,126 of lentinan 23:130 Antitumor glycoprotein ARS-2 30:778 from Chlorella vulgaris strain CK 30:778 Antitumor immune response 26:921-923 Antitumor immuno-active glycoprotein 30:776 from Chlorella vulgaris strain CK 30:776
Antitumor immuno-activity 25:432 of Chlorella vulgaris strain CK 22 (CVs) 25:432 Antitumor immunopotentiation 25:454 Antitumor lignans 26:211 austrobailignans- 1 as 26:211 burseran as 26:211 (+)-dimethylisolariciresinol-2axyloside as 26:211
(-)-trans-2-( 3 ",4"-dimeth yo xyb enzyl)-3-(3 ',4 '-methylene dioxybenzyl) butyrolactone as 26:211 diphyllin as 26:211 diphyllin acetate as 26:211 justicin-D as 26:211 peltatins as 26:211 podophyllotoxins as 26:211 stegnangin as 26:211 stegnanol as 26:211 Antitumor mechanism 27:831 of guidimacrin 27:831 Anti-tumor metabolites 1:239 Antitumor plant product 23:71 Anti-tumor promoter 5:377;24:215-267 curcumin as 24:215-264 Antitumor promoter activity 21:585,705 Anti-tumor promoting activity 23:444, 670,841 of tannic acid 23:444 of tannins 23:444 Antitumor substance 28:569,570 egosterol as 28:570,572 from Agaricus blazei 28:569 isolation of 28:569 mechanism of 28:569 Antitumor therapeutic agent 30:840 Antitumor tubeimosides 21:730 Antitumor vascular inhibition 24:406 of phosphocombretastatin (Disodium salt) A-4 24:406 Antitumoral agent 30:691 for skin cancer 30:691 use of Maytenus amazonica 30:691 Antitumoral immune responses 26:923, 924,929 Antitumoral uses 30:732 of plants 30:732
61
Antitumorigenic agent 23:478 Anti-tumour-promoting activity 21:642; 24:215-264 ;25:46;30:695 Antitumour-promotor 25:44-46,60 antioxidant activites of 25:59 from herbal drugs 25:44 Antitumour activity 22:97-100,361 of 3',4-O-dimethylcedrusin 22:361 of friedelone 22:97-100 of hopane quassionoid 22:97-100 oflanostane lupane 22:97-100 of oleanane 22:97-100 Anti-tussive activity 17:633;28:200 of genus Morus 28:200 Antiulcer activity 22:410,419 Antiulcerative properties 21:410 Antivectorial activity 21:591 Anti-venom alkaloid 1:239 oxidation 1:239 Antiviral activities 5:461,563;10:608, 609,619,620;17:146;21:132,148, 150,393,435,600,615,662,690,718; 22:307,361 ;23:233,268,233,346,395, 473,512,531,703;25:114;26:169,222, 224,226,344,452,741,759;27:482; 28:257,293 ;30:224,324-326,393,394, 395,398,401-405,407,410-412,627, 742 against Herpes simplex virus 17:146 against HIV-1 30:398 against HIV-2 17:146;30:398 against HSV 30:401 against HSV-1 30:401 against plant virus infection 30:412 against sandfly fever sicilian virus (SFSV) 30:410 in cell cultures 30:394 in mouse models 30:405 in vitro 30:401,404,405 of (-)-aristeromycin 10:609 of (+)-C-2'-ara-fluoroguanosine 10:609 of 2-amino oxetanocin-A 10:620,621 of 3',4-O-dimethylcedrusin
22:361 of 3'-azido-3'-deoxythymidine 10:585 of aciclovir (9-[2-hydroxyethoxy)methyl] guanine 10:585 of allicin 23:473 of Astragalus brachycentrus 30:405 of Astragalus echianaeformis 30:405 of Astragalus membranaceus 27:482 of carbocyclic oxetanocin A and G 10:620,621 of carbovir 10:608,609 of carrageenans 30:410 of cationic polysaccharide (PS) 30:402 of D-2'-deoxycarbocyclic guanosine 10:608,609 of defensins 23:346 of dextran sulphate 30:410 of didemnins 10:253,254 ofeudistomin E 23:268 of flavonoids 17:145;22:307 of fucoidan 30:410 of Hernandia perforatum 30:407,627 of Ichyroclineflaccida 30:401 ofimidazole analogues 5:566 of lignans 5:461 of mannans 30:402 of marine organisms 5:359,364 ofmycalamide A 5:366 of Nothogeniafastigiata 30:404 of OGs 25:114 of oleanolic acid derivatives 17:135 of oxetanocin A 10:608,619,620 of oxetanocin G 10:619,620 of pentosan polysulphate 30:410 of Podophyllum extracts 26:169 of polyphenols 28:257,293; 30:224 ofpolysaccharides 30:393,395 of quinones 30:324-326 of quinovic acid derivatives 17:134 of resveratrol 23:531
62
of saikosaponins 23:512 ofSambucus nigra 30:407 ofSaponaria officinalis 30:407 of spermidine 5:563 of Sterculia urens Roxb. 405 of sulphated galactan 30:402 of sulphated polysaccharide (PS) 30:403 of tannic acid 23:395 of Theonella sp. 5:364 of verrucosin 26:228 of xylogalactans 30:402 of yeast mannans 30:412 of [3-carboline alkaloids 23:233 on infected vero cells 30:410 Antiviral activity 30:405 of tragacanthin polysaccharide (PS) from 30:411 Antiviral agent 19:351,511 ;24:474-555; 30:394,399,402,405,408 acyclovir as 24:474,486 cidofovir as 24:486,487 didanosine as 24:474,486,488 forscarnet as 24:486,487 from calcium spirulan as 30:399 fucoidan as 30:405 ganciclovir as 24:474,486 in vitro as 30:408 in vivo testing of as 24:491 lamivudine as 24:488 sorivudine as 24:474,486 stavudin as 24:474,486,488 sulphated phyto-PS as 30:402 trifluridine as 24:487 zalcitabin as 24:474,486,488 zidovudine as 24:474,486,487 Antiviral antibiotic 21:407 Antiviral chemotherapy 30:394 Antiviral compounds 24:492-544 alkaloids 24:527-533 buntenolides 24:521,522 carotenoides 24:533-540 chromones 24:499-503 coumarins 24:499-503 iridoids 24:510-521 lignans 24:503-509 macrolides 24:541-544 marine-derived 24:526-543 N-containing compounds
24:527-533 nucleosides 24:527-533 peptides 24:522,527-533 phenolics 24:503-509 phenyl propanoids 24:503-509 phospholipids 24:521,522 polyacetylenes 24:521,522, 541-544 polysaccharides 24:540,541 prostaglandins 24:541-544 proteins 24:522,527-533 pyrones 24:541-544 quinone 24:503-509,541-544 steroids 24:510-521,533-540 tannins 24:510-521 terpenes 24:510-521 terpenoids 24:533-540 thiophenes 24:521,522 xanthones 24:503-509 Antiviral drugs 30:742 Antiviral effect 23:135;30:627 of [3-glucans 23:135 of hypericin 30:627 mechanism of action of 30:627 Antiviral efficacy 30:408 of natural polysaccharidic-related materials 30:408 of pine cone extract 30:408 Antiviral factor (AVF) 24:524 Antiviral glycopeptide 24:524 meliacin as 24:524 Antiviral microbial-derived compounds 24:544-555 actinomycin D 24:547 ansamycin 24:545-546 aphidicolin 24:549 bleomycins 24:547,548 cardyceptin (3 '-deoxyadexosin) 24:547 cytochalasins 24:549 distamycins (pyrrole amidines) 24:546 dounomycin 24:547 doxorubicin 24:547 filipin 24:548 gliotoxin 24:545 mithramycin 24:547 mycophenolic acid 24:549 rifamycin-type macrolides
63
24:545,546 sinefungin 24:547 toyocamycin 24:547,548 Antiviral polyanionic properties 30:404 Antiviral properties 30:407409 of polymeric carbohydrates 30:409 ofpolysaccharide (PS) 30:407 Antiviral protein 13:655 Antiviral screening 30:411 Antiviral screening assays 24:484,490 in vitro 24:484,490 Antiviral substances 30:394,395 from plant kingdom 30:395 from plants 30:394 Antiviral sulphated polysaccharide (PS) 30:408 Antiviral treatments 30:407 Anti-vitamin activity 9:519 of 25-aza-vitamin D3 9:519 Anti-ct-D-mannose antibodies 29:559 against Staphylococcus aureus 29:560 in hormone therapy 29:561 in serological development 29:560 in vaccine production 29:560 Ants 6:434-444 chemical defense in 6:421-465 pipeidine alkaloids in 6:422-434 pyrrolidine venom alkaloids in 6:434-444 Anxiety 30:368 role of serotonin (5-HT) in 30:368 Anxiolytic activity 28:177 of Ginkgo biloba L. 28:177 Aokumanol 23:815 Aopinolide 23:813 synthesis of 23:813 Apaenogaster rudis 5:254,255 Apergillus oryzae 18:807 monohexosylceramides from 18:807 Aphaenogaster longiceps 5:252 Aphanamyxis sp. 21:124 Aphanizomenon flosaquae 26:353 Aphanizomenon sp. 26:352,358 Aphanocapsa feldmanni 21:367
Aphanomyces 22:493 Aphanomyces cochlioides 22:482 Aphanomyces euteiches 22:482 Aphanomyces raphani 22:482 Aphelandra tetragona 27:191,193 Aphelasteriasjaponica 15:69 Aphelasteroside A and B 15:68
Aphelencoides besseyi 26:434,436, 439,465,469
Aphelencoides tritici 26:438,469 Aphid antifeedant activity 23:304 ofbrucein B 23:304 ofisobrucein A 23:304 of quassin 23:304 Aphid antifeedants 23:304 quassinoid activity as 23:304 Aphidicolan-type diterpenoids 21:694 Aphidicolin 14:583;21:136,721; 22:217,234;24:549 antiviral microbial-derived compound 24:549 Aphidicolin-17-glycinate 22:235 Aphidius rhopalosiphi 27:213 Aphis gossypii 23:666 Aphomia melleus 15:387 Aphomia oniki 15:383 Aphomia sociella 15:384 apigenin-7-O-glucoside from 28:167 bilobetin from 28:166 biological activities of 28:165 chemistry of 28:165 delphidenon from 28:167 ginkgetin from 28:166 ginkgolide A from 28:170 ginkgolide B from 28:170 ginkgolide C from 28:170 ginkgolide J from 28:170 ginkgolide M from 28:170 isoginkgetin from 28:166 isorhamnetin from 28:167 isorhamnetin-3-O-glucoside from 28:167 isorhamnetin-3-O-rutinoside from 28:167 kaempferol from 28:167 kaemp ferol- 3- O-(2"- Oglucosyl)rhamnoside from 28:167
64
kaempferol-3-O-(6"'-O-pcoumaroyl-2"-O-glucosyl) rhamnoside from 28:167 kaemp fero 1-3-O-[ 6" '-O- {p-(7 ....O-glucosyl)coumaroyl}-2"-Oglucosyl]rhamnoside from 28:167 kaempferol-3-O-[c~-rhamnosyl( 1---~2)- c~-rhamno syl- ( 1~ 6)]- [3glucoside from 28:167 kaempferol-3-O-glucoside from 28:167 kaempferol-3-O-retinoside from 28:167 kaempferol-7-O-glucoside from 28:167 luteolin from 28:167 luteolin-3'-O-glucoside from 28:167 4-O-methylpyridoxine from 28:172 myricetin from 28:167 myricetin-3-O-rutinoside from 28:167 quercetin from 28:167 quercetin-3-O-(2"-O-glucosyl) rhamnoside from 28:167
quercetin-3-O-(6"'-O-p-
coumaroyl-2"-O-glucosyl) rhamnoside from 28:167 quercetin-3-O-[6"'-O- {p-(7 ....-Oglue o syl) c oumaroyl }-2"- Oglucosyl]rhamnoside from 28:167 querc etin- 3-0-[ 6" ' - O-p- c o umaroyl-2"-O-glucosyl) rhamnosyl-7-O- glucoside from 28:167 quercetin-3-O-[c~-rhanmosyl( 1---~2)- ~-rhamno syl-( 1-~ 6)- [3glucoside from 28:167 quercetin-3-O-glucoside from 28:167 quercetin-3-O-rhamnoside from 28:167 quercetin-3-O-rutinoside (rutin) from 28:167 sciadopitysin from 28:166
API 29:591 effects on cathepsin D 29:591 Apiaceae 21:615 Apicomplexan 26:804 Apicularens 25:728 Apiculture 28:390 acaricides in 28:390 Apidae 6:421 Apigenin 22:423,438;25:541,544,594; 26:746,750,763,802;29:572;30:284, 725,727 effects on HIV-1 protease 29:572 effects on aminopeptidase N 29:577 ~H-NMR data of 30:284 structure of 30:725 Apigenin 7-glucoside 23:342 Apigenin 7-rutinoside 23:747 Apiguard 28:391 for thymol-based acaricide 28:391 Apiin 25:595 Apilife VAR 28:391 as Frakno thymol frame 28:391 c~-Apiodionen 28:117 as topoisomerase inhibitor 28:117 [3-Apiodionen 28:117 as topoisomerase inhibitor 28:117 D-Apiofuranosyl 15:7 Apioglycyrrhizin 15:26 Apiosordaria effusa 28:117 Apiospora montagnei 21:216 apiosporamide from 21:216 Apiosyl glucosides 5:643 Apis mellifera 28:387,393 Apium graveolens L. 22:512;29:83,573, 581,589 Apium sp. 27:686 Apiyski brasiliana 25:702,717,785,801 Aplasmomycin 21:316 Aplasmomycin B 19:587 Aplasmomycin C 19:587 Aplidites A-G 19:617 Aplidium albicans 27:804 Aplidium californicum 10:248;18:716 Aplidium cavernosa 10:248
65
Aplidium constellatum 10:248 Aplidium genus 25:837 Aplidium meridianum 25:764 Aplidium multiplicatum 23:185,196 Aplidium pliciferum 23:235;28:635 Aplidium sp. 5:440,617;10:244,248 Aplidium uouo 28:644 Aplinia sp. 17:358 Aplydilactone 17:6 Aplykurodin A 17:5 Aplyronines A-C 19:609 cytotoxic activities of 19:609 Aplysia brasiliana 6:6;9:249;18:625 Aplysia dactylomela 5:368;6:35;17:7, 8,430 Aplysia faciata 17:6 Aplysia fistularis 25:787 Aplysiajuliana 17:6 Aplysia kurodai 6:24,56;17:4,6;28:648 Aplysia punctata 17:9;25:769 Aplysia sp. 5:368;25:724 Aplysiapyranoid A-D 17:5 Aplysiatoxins 18:294,549 Aplysilla glacialis 17:14,15 Aplysilla rosea 6:107 Aplysilla sulphurea 17:11 12-epi-Aplysillin 17:12 Aplysillin 6:107,109 Aplysillin A 28:697 as thrombin receptor antagonist 28:697 Aplysina aerophoba 21:259,260;25:712 aerophobin-1 from 21:259 isofistularin-3 from 21:259 Aplysina archeri 25:720 Aplysina cauliformis 25:766 Aplysina fistularis 17:103;21:307,308; 26:86;28:697 Aplysina sp. 25:17,707 Aplysinopsine 5:410;23:258 cytotoxic activity of 5:410 Aplysiotoxin 25:771 (-)-Aplysistatin 16:705 antineoplastic agent 16:705 Apo-carotenoids 30:516,528,540 stretching vibrations in 30:540 Apocynaceae 21:3,129;25:249 Apogen 22:44 Apollonias barbujana 26:850
Apomorphine-binding sigma receptors 25:538 f3-Apopicropodophyllin 26:193 ;213,214 cytotoxicity of 26:213 immunosuppressive activity of 26:214 Apoplastic fluids 25:400 Apoprotein 30:534 X-ray data of 30:534 Apoptic body formation 25:466 Apoptosis 22:444;25:268,269,272; 26:752,922,925,993,1262,1264, 1289;27:86-88;28:175 in cerebellar granulosa cells 25:269 in primary granulosa cells 25:269 in susceptible Burkitts lymphoma (BL) 25:272 in viral infections 24:478-480 ofbilobalide 28:175 of ginkgolide B 28:175 of ginkgolide J 28:175 relation with lipid peroxidation 27:86-88 role of 3-(4,5-dimethylthiazol-2yl)-2,5-diphenyl tetrazolium bromide 28:175 role of cerebellar granule cells 25:268 Apoptosis 23:497;26:752,922,925,993, 1262,1264,1289 Apoptosis-inducing activity 23:97 on human leukemia 23:97 Apoptotic bodies 25:469 Apoptotic bodies formation 25:468 Aporphine alkaloids 21:68;25:544 apomorphine 25:544 boldine 25:544 Aporphine isoquinoline alkaloids 25:527,530,543 xylopinine 25:530 isocorydine 25:530 Aporphines 21:57,73,79;22:19,22 Appetite suppression 30:194 due to opioids 30:194 Apple dihydrochalcones 23:744 Application 27:322 ofabscisic acid 27:322
66
of cholelithiasis 27:382 ofcyclodextrins in GC 27:368 Aprotinine 24:524 as protease inhibitor 24:524 Apuleia leiocarpa 5:679,680 Apulein 5:680 Apuleisin 5:680 Apurinic sites 22:27 Aquafoliacese 9:402 Aquillochin 5:5,6,8 Aquillochin diacetate 5:7-9 APT spectrum of 5:7 ~3C-NMR spectrum of 5:9 ~H-NMR spectrum of 5:9 selective INEPT spectrum of 5:9 Ara-A 21:252 Arabidopsis 25:368,391,395,413,422, 426,660 Arabidopsis cultivar 25.418,419; 26:933,1289 mutant detz 25:419 mutant saxl 25:418 Arabidopsis dwarf 25:414 Arabidopsis genes 25:414 mutated 25:414 Arabidopsis thaliana 18:721 ;25:377, 385,496;26:478,945,948,1268,1289; 27:322,331 ;29:59,603,607,612,613 Arabino-2-hexulopyranose 15:190 DArabinofuranose 6:352,335 Dphosphorus analogs of 6:352,335 Arabinogalactan 26:1156 Arabinogalactin 15:36 Arabinoglucoronopyranosides 7:435 ofoleanolic acid 7:435 Arabino-hexofuranose 6:376 DC6-P bond analogs of 6:376 L-Arabinopyranosyl 15:7 3-O-[cx-L-Arabinopyranosyl (1---~2)-[3D-glucopyrano-syl]-3 [3,713,18,20,26pentahydroxy-(20S)-damunor-24ene 21:733 L-Arabinopyranosyl unit 15:21 c~-L-Ar ab inop yrano syl- ( 1---~2)- [3-Dglucopyranosyl 21:732 3-O- [a-L-Arabinopyranosyl-(1 ~2)-13D-glucopyrano-syl-]-bayogenin-28-
O- [c~-L-rham-nopyranosyl-(1 ~2)-aL-arabinopyranosyl] ester 21:732 D-Arabinose Arabinose 7:136,139;22:312;23:163; 30:433 reaction of 30:433 L-Arabinose 7:144,181,294,298;11:7,8; 30:452 allylation of 30:452 Arabinosidasic 24:994-998 enzymatic activity 24:995-998 3-Arabinoside 23:745 Arabinosyl cobaltoxime 30:449 Arabofuranosides 5:657 Araboglycyrrhizin 15:26 Arabopyranosides 5:657 Arabsin 7:231 Arachidonamide 9:582 Arachidonate 5-1ipoxygenase 28:216 Artocarpus flavonoids against 28:216 Arachidonate 5-1ipoxygenase activity 28:216 of artonin E 28:217 of morusin 28:217 Arachidonate oxygenase activity 28:217 Arachidonate-5-1ipoxygenases 29:672 adjusting immune response 29:672 as chemotactic agents 29:672 in B lymphocytes 29:672 m basophils 29:672 in eosinophils 29:672 m macrophages 29:672 in mast cells 29:672 m monocytes 29:672 m polymorphonuclear leukocytes 29:672 inducing cell adhesion with 29:672 origin of 29:672 Arachidonic acid 21:657,744;25:66, 263,274,275,333,596,597,616,66; 26:758,759;27:422;30:192,225,594 from phospholipids 27:422 inhibition of 25:66 leukotrienes from 30:225 metabolism of 26:265-268
67
platelet aggregation induced by 30:594 Arachidonic acid cascade 22:434 Arachidonic acid induced edema 25:46 inhibition of 25:47 Arachidonic acid metabolism 20:514; 27:693 Arachidonic acid methyl ester 2:12 CI(NO) mass spectrum of 2:12 Arachiniodes exilis 27:35 Arachiniodes sporadosora 27:35 Arachis hypogaea 25:93;29:598 Arachnida 28:382 class of 28:382 Arachniodes exilis 15:33;27:18,35 Arachniodes sporadosora 15:33; 27:18,35 Arachnoideum sp. 26:685 Aralia continentalis L. 22:512 Aralia elata 21:655,666;24:273 triterpene saponins from 21:655 Araliopsis tabouensis 2:121 Araneosol 7:226 Araucaria bidwilli 25:249 Araucaria cookii 17:36 Araucaria cunninghamii 17:36 Araucaria excels 25:249 Arbacia lixula 15:104 Arbacia punctulata 7:303 Arbiglobin 7:234 Arbol negro 23:657 Arborescidimes A 23:263 (+)- l, l O-epi-Arborescin 14:365,366 Arborinane 25:54 Arbortristosides A&C 26:807 Arbus cantoniensis 25:91 Arbusculin A 27:549 Arbusculin A-D 7:231,232 Arbusculin E 7:234 Arcanose 4:255 Arcapillin 7:226 Archaebacteria metabolism 25:939 Archangelicin 23:351 Archaster typicus 7:304-306;15:74,84 Archniodes sporadosora 27:35 (-)-Arctigenin 24:742 Arctigenin 5:522;26:192,217,218,233, 241,269 as PAF-induced inhibitor 26:241
of methyl ether 26:192,241 Arctigenin 4'-O-glucoside 5:490,491 Arctigenin methyl ether 26:241 as PAF-induced inhibitor 26:241 Arctigenin monoacetate 18:601 Arctiin 5:475,476,489-491,522;26:192, 237 Arctium lappa 5:497;26:217,233,241 ; 25:944 arctiin from 26:217 arctigenin from 26:217 Arctomecon genera 27:163 Arcyria cinerea 29:236 Arcyria denudata 5:55;21:263;29:225, 236 arcyriaflavin from 21:266 arcyriaflavin-B from 12:366,370 arcyriaflavin-C from 12:366,370 arcyriarubin A from 12:366,370 arcyriarubin B from 12:366,372 arcyriarubin C from 12:366,372 arcyriaverdin C from 12:366,372 arcyoxepin A from 12:367,373 arcyroxepin B from 12:367,373 arcyroxindole A from 12:367, 372 arcyroxocin B from 12:367,372 dihydroarcyriarubin B from 12:366,370 Arcyria feruginea 29:258 arcyriarubin C from 12:366,372 Arcyria natans 29:236 arcyriacyanin A from 12:366, 372 arcyriaflavin-A from 12:366,370 arcyrioxocin A from 12:367,472 dihydroarcyriacyanin A fi-om 12:367,372 Arcyria sp. 12:367,373 arcyrin A from 12:367,373 arcyrin B from 12:367,373 Arcyriaflavin B 5:55,56 Arcyriaflavin C 1:3;5:55,56 Arcyriaoxocin A 29:227 against human cancer cells 29:229 against protein kinases 29:229 biological activity of 29:229 for anticancer drugs 29:229
68
mode of action of 29:229 synthetic routes to 29:227 Arcyrin arcyrinin model compounds 12:383 from N-methylarcyriarubin A 12:383 synthesis of 12:383 Arcyrinin B 12:367,373 Arcyroxepin B 12:367,373 Arcyroxindole A 12:367,373 Arcyrioxocin A 12:367,372 Arcyroxocin B 12:367,372 Ardeola ibis 5:837 hemoglobin components of 5:837 Ardisia colorata 30:161 cytotoxic activity of 30:161 effect on FM3A cells 30:161 Ardisia crenata 26:8 Ardisiajaponica 13:660;17:117,127 Areca catechu 13:660;24:272;29:578 arecoline from 13:660 Areca II-5-C (tannin) 29:578 effects on ACE 29:578 Arecaidine 21:84 Arecoline 22:17,736 Arecoline sp. 25:530 Arelia cordota 20:690 Arenaria filicaulis 26:52 Arenaria kansuensis 18:721 Arenarol 5:458;15:315 Arenarone 5:438 cytotoxic activity of 5:438 Arenastatain A 25:714,717 Arenavirus replication 30:412 inhibitory effect on 30:412 Arene carbene 3:324,325 Arene-metal n-complexes 20:310-312 Arene-olefin metaphotocycloaddition 3:14 Arenes 27:749,754 hydroxylation of 27:749,754 microbial oxidation of 18:430-432 Arenesulphonyl-5-(pyridine-2-yl)tetrazolides 13:275 Arg557-Ile558 30:838 Arg-D-Trp-NmetPhe-D-Trp-Met-NH2 27:799
as anticancer peptide 27:799 Argemone genera 27:163 Argemone mexicana 26:435 Argentation chromatography 9:450,460, 464,465 Argentation TLC 9:333,338,343 Argentilactone 19:463,494 Argentinian Baccharis spp. 30:730 structure of 30:730 Argentiolide A 7:211,231 Argentiolide B 7:230 Arginine 22:390 Arginomonas non-fermantans 25:155 Arglanilic acid methyl ester 27:557 Arglanine 7:232,234;27:549 Argogorytes fargei 5:225,250,253 Argogorytes mystaceus 5:225,231, 252,253 Arguticinin 5:202,203;9:66 Argutinin 5:203;9:66 Argylioside 7:443 Aricine 9:174 Arisaema amurense 22:512,513 for convulsions 22:513 mrisaema amurense vat. serratum 22:512 as anticonvulsant 22:512 Arisaema consanguineum 22:512 for convulsions 22:512 Arisaema grammicola 22:579 Arisaema heterophyllum B. 22:512 for epilepsy 22:512 Arisaema heterophyllum B. 22:512 for epilepsy 22:512 Arisaemajaponicum 22:513 Aristea ecklonii 2:224 Aristeguetia bulleaefolia 25:251 (-)-Aristeromycin 10:609 antiviral activity of 10:609 Aristeromycin 8:140 Aristlane 18:607 Aristocarbinol 9:172 Aristolasicol (aristotelin- 19-ol) 9:172; 11:305,312 Aristolasicone 9:172 9-Aristolene 23:162 Aristolochia argentina 19:494
69
Aristolochia indica 22:27 aristolactam-N-beta-D-glucoside from 22:27 Aristolochia spp. 21:97 Aristolochic acid 21:97 Aristolone 20:464 (-)-Aristomakine 11:301,302 (-)-Aristomakinine 11:301,302 relative configuration of 11:301-303 Aristone 11:277 Aristoserratine 9:171 (+)-Aristoserratine (aristotelin- 15-one) 11:296 absolute configuration of 11:296 X-ray crystallography of 11:296 Aristotelia australasica 11:293,317 allo-aristoteline (epi- 11aristoteline) from 11:317 aristolasicone from 11:312 (+)-aristoserratenine from 11:293 3-epi-aristoserratenine from 11:293 Aristotelia fruticosa 11:278,324 (+)-aristofruticosine from 11:324 (+)-fruticosonine from 11:278 Aristotelia serrata 11:278,296,301 (-)-aristomakine from 11:301 (-)-aristomakinine from 11:301 (+)-aristoserratenine from 11:293 (+)-aristoserratine from 11:296 (-)-hobartine from 11:278 8-2H-Aristoteline 11:311 Aristotelone 11:321,322 Aritason 20:13 Arjunglucoside 1 23:515 Arjunic acid 7:133,134 glycosides of 7:133,134 from Terminalia alata 7:134 Arjunosides I-IV 7:133 from Terminalia arjuna 7:133 [3-ARK I 21:264 Arlatin 7:234 Armefolin 7:232;27:550 Armexifolin 7:232 Armexine 27:550
Armillaria mellea 5:289,290;22:513 Armillaria nova zelandiae 21:196 Armin 7:232 Army worm (Spodoptera frugiperda) 14:451 Arndt-Eistert homologation 1:237; 13:116 Arndt-Eistert reaction 13:79,93 Arnica acaulis 29:90 Arnica chamissonis 29:90 Arnica montana 26:808;29:90 Arnica spp. 29:577 Arnicenone 3:6,60 Arnidoil 22:122 Aromadendrane 14:355;15:227;18:607 Aromadendrane 25:848,850 (+)-4-epi-Aromadendrene 14:359,362 Aromatase inhibitor 28:16,17 albanol A as 28:17 broussoflavonol F as 28:17 broussonin A as 28:16 demethylmoracin I as 28:18 Aromatic acetylenes 7:222 Aromatic alkaloids 23:233-283 Aromatic amines 27:749 oxy-functionalization of 27:749 Aromatic aminoacids 23:240 metabolites of 23:240 Aromatic chromophores 2:171,172; 12:46,47 Aromatic compounds 6:509;23:638 oxidation of 6:509 Aromatic L-amino acid decarboxylase (AADC) 30:370,380 activity in metabolic pathways 30:380 Aromatic phosphoramidates 14:286 Aromatic triterpene 30:682 species of 30:682 pristimerin 30:682 tingenone 30:682 Aromatization 7:360-363;11:114-119; 27:782 of N-heterocyclic ring 27:782 Arossostephium chinese L. 22:518 [3-Arotene monocation 30:548 structure of 30:548 Arrabidaea platyphylla 22:513 for epilepsy 22:513
70
Array processor 2:113 Arrow poisons 12:233 ARS2 25:435,451;30:776 antitumor activity of 25:438,451; 30:776 effect on enzyme hydrolysis 30:777 effect on periodate oxidation 30:777 ARS-2 mediated cellular activation 30:781 Arscotin 7:224 Arsenic-containing ribofuranosides (ACRs) 25:867 Artabin 27:558 Artabortrine 20:480,481 Artabotrys zeylanicus 20:480 dioxoaporphines of 20:480 Artabsin 7:234;27:575 Artabsinolide A-D 7:234 Artabsinolide B 7:209,210,234 Artanin 7:204,205,224 Artanomalolide 7:239 Artausin 7:234 Arteannuin B 7:217;22:153 from Artemisia annua 7:217 Arteannuinic acid 7:238 Arteanoflavone 7:226 Arteanomalactone 7:230 Artecalin 27:550 Artecanin 27:575 Artecanin hydrate 7:234 Artedouglasia oxides 9:531-533 Artedouglasia oxides A-D 7:217,218 Arteether 22:154;26:833 Artefransin 7:234 Arteglasin A 27:575 Arteglasin A,B 7:234 Artelin 7:225 Artelinate 26:833 Artemether 22:154;26:832,833 Artemetin 7:206,226 Artemia salina 9:385,387;21:257; 22:577,629;23:170;26:703 Artemidin 7:203,223 Arteminolide 24:457 FPTase inhibition by 24:403-464
Artemisia abrotanum 7:205,218,240 coumarin-sesquiterpene ethers in 7:205 Artemisia absinthium 7:215,219,220, 240;28:425,426 absinthin from 7:215 acaricidal activity of 28:425 against aphids 28:425 as insecticide 28:425 Artemisia alcohol 9:530 Artemisia annua 22:146;26:363,783, 801,831 artemisinin from 13:657;20:518 arteannuin B from 7:217 candinane derivatives from 7:217 Artemisia anomala 7:215,240 aurantimide acetate from 7:220 simiarenol from 7:218 Artemisia aragonensis 7:212 Artemisia arborescens 27:376 Artemisia arbuscula 7:208 arbusculone from 7:208 Artemisia argyi 7:218 simiarenol from 7:218 Artemisia aucheri 7:208,241 Artemisia austriaca 7:241 C-methylflavone in 7:207 Artemisia californica 20:4 Artemisia cantabrica 7:216,242 Artemisia capillaris 7:220,242;23:341 Artemisia carvifolia 7:206,242;29:574 Artemisia compacta 7:205,243 Artemisia douglasiana 7:203,204,217, 218,243;29:90 Artemisia dracunculus 7:220,243; 29:577 Artemisia feddei 7:208 filifolide A from 7:208 filifolone from 7:208 Artemisia fragrans 7:208,244 Artemisia genus 27:376 Artemisia glutinosa 7:220,244 Artemisia gypsacea 7:211,245 Artemisia herba alba 7:212,217,245; 17:475 ;24:65,79 ;27:376 Artemisia hispanica 7:216 elemanolide from 7:216 2ot-hydroxyartemorin from
71 7:211 tamaulipin A from 7:211 Artemisia inculta 7:217,245 Artemisia iridentata ssp. rothrockii 7:208,252 Artemisiajudaica 7:211,216,217,246; 27:376 Artemisia klotzchiana 7:214,246 Artemisia koidzumii 7:218,246 Artemisia laciflora 7:203,218,246 Artemisia laciniata 7:215,216,246; 9:529,531,533-535 Artemisia lanata 7:214,246 Artemisia latifolia 7:219,247 Artemisia leucodes 7:215,247 Artemisia longloba 7:218,247 Artemisia ludoviciana 7:203,247;29:87 Artemisia maritima 7:217,427;13:660; 24:54,77 Artemisia marschalliana 7:220,248 Artemisia molinieri 7:218,248 Artemisia monosperma 7:204,220,248 Artemisia montana 25:944;27:418 Artemisia montana extracts 27:420 biological activity of 27:420 Artemtsza moorcrofiiana 9:529,530,534 Artemtsta pallens 7:217,249;9:531 Artemtsta palustris 7:207,220,249 Artemisia pectinata 7:214,216,249 Artemisia persica 7:217,249 Artemtsta princeps 25:944;27:418; 29:87 Artemisia roxburghiana 7:219,250 Artemisia rupestris 7:218,250 Artemista rutifolia 7:215,250 Artemisia salsolodes 9:529-531,533,534 Artemisia santolina 7:212,250 Artemisia santonicum 7:212,250 Artemisia schmidtiana 14:450 eudesm-11-en-4-ols from 14:450 neointermedeol from 14:450 Artemisia selengensis 7:203,204, 215,251 Artemisia sp. 7:201-263;9:529-536; 25:944 ;27:418,847 ;29:88,580 Artemisia szowitziana 7:216,251 Artemisia toumefortiana 7:212,252; 24:79 Artemisia tridentata 28:408
Artemisia umbelliformis 7:215,253 Artemisia valentina 7:213,218 Artemisia verlotorum 22:513 Artemisia vulgaris 7:120,208,215, 218,253 Artemisia xanthochroa 7:215,253 Artemisin 24:77 Artemisinin 23:488;26:363,446,779, 783,807,809,811,825,832-834,840 Artemisiten 22:161 Artemorin 7:209,210,230;27:558 Artemorin-4ot,5 [3-epoxide 27:558 Artenolide 7:239 Arterial thrombosis 30:593 due to platelet aggregation 30:593 Arteriosclerosis 30:55,56,58,70 Ganoderman lucidum in treatment of 56,58 prevention of 30:56 role of natural products in 30:55 use of Laminaria japonica Aresch in 30:56 Artery constriction 30:55 Artery relaxation 30:72 by chalcones 30:72 Artesieversin 7:239 Artesin 7:212,213 11-epi-Artesin 7:213 Artesovin 7:216 from Artemisia szowitzian a 7:216 Artesunate 26:833 Artevasin 7:230 Arthricular synovial membrane 30:689 inflammation of 30:689 Arthritis 26:50;30:58,193 Ganoderman lucidum in treatment of 30:58 Herniaria hirsuta in 26:50 use of capsaicin in 30:193 Arthrobacter globiformis 9:418;
26:1263,1268-1270,1272,1278-1280
Arthrobacter ilicis 25:719 Arthrobacter simplex 9:418,427,428 Arthrobacter sp. 26:1122,1124 Arthrobotrys oligospora 26:431,432, 449
72 Arthropod alkaloids 11:231 from Solenopsis sp. 11:231 Arthropod ectoparasites 12:7 Arthropoda 19:627 Arthropod-borne diseases 28:394 of humans 28:394 of livestock 28:394 zoonotic as 28:394 Artichoke phenolics 23:753 Articulin 30.'708 structure of 30:708 Articulin acetate 30:734 cytotoxic activity of 30:734 Artificial electron mediators 20:821-824 Artimisinin 25:350 Artobiloxanthone 28:201,229 biological activity of 28:229 from moraceous plants 28:201 Artocarpesin 28:201 from moraceous plants 28:201 Artocarpus altilis 28:202 Artocarpus communis 28:202;29:706 Artocarpus elasticus 29:790 Artocarpus flavones 28:216 5-1ipoxygenase activity of 28:216 Artocarpus flavonoids 28:203,216,220 against arachidonate 5-1ipoxygenase 28:216 against TNF-c~ release 28:220 Artocarpus heterophyllus 22:513; 27:842 ;28:202 ;29:580 as sedative for convulsions 22:513 Artocarpus nobilis 2:231 Artocarpus rigida 28:202 Artocarpus sp. 28:203 Artocarpus venenosa 28:202 artobiloxanthone from 28:202 artonin E from 28:202 cycloartobiloxanthone from 28:203 isoprenylated flavonoids from 28:202 use against inflammation 28:202 use in malarial fever 28:202 use as folk medicine 28:202 use in malarial fever 28:202
Artonin E 28:201,215,229 as 5-1ipoxygenase inhibitor 28:215 biological activity of 28:229 Arugomycin 19:118 Arusgospongines A,B,C,D.E,F,G,H and J 21:267 Arxulla adeninivorans 25:150 Aryl coumarins 24:799 derivatives of 24:740,741 ot-Aryl enamine substrates 18:327 ~-Aryl enamine substrates 18:333 Aryl ethano-bridge 11:295 Aryl methyl ketone 14:473 chiral acetal of 14:473 asymmetric cyanation of 14:473 cis-3-N-Aryl sufonamido borneol 4:661, 662 Aryl [3-C-glycosides 10:377 by condensation with tribenzyloxy benzene 10:377 by Lewis acid assisted condensation of aryl ether 10:375 1-Aryl-2-methyl cyclohexane 8:9 1-Aryl-2-methyl cyclopentane 8:9 2-Aryl-3-methyl-4-benzyltetrahydrofurans 17:331 Arylacetones 30:217 4-Arylamino 24:740,741 2-Arylbenzofuran 28:226 as anti-HIV flavonoids 28:226 2-Arylbenzofuran synthesis 30:223 from benzylalcohols 30:223 Aryl-C-glycosides 10:362,363; 11:139-142 by condensation 11:139-142 from ribofuranosyl chloride 10:362,363 via polyketides 11:139-142 synthesis of 11:139-142 4c~-Aryl-cis-decahydroisoquinolin 6formate 12:462 Arylcycloalkanes 8:6 4c~-Aryldecahydroisoquinolines 18:81 Aryldihydronaphthalenes 17:337 Arylethanals 30:214 acid treatment of 30:214
73 aldol condensation of 30:215 2-phenylnaphthalene from 30:214 1,2,9,10-tetrahydro- 1,9epoxydibenzo[a,e]cyclooctenes (Kagan's ether) from 30:214 Arylethanoid derivatives 30:213 reaction of 30:213 N-Arylethylhydroindoles 3:457 C-Arylglycals 10:344 by palladium catalyzed coupling 10:344 synthesis of 10:344 N-(Arylidene) benzyl amines 1:343 2-azaallyl anions from 1:343 isomerization of 1:343 Aryllactic acid 30:216 decomposition of 30:216 Arylnaphthalene lignans 26:194 Arylnaphthalenes 5:493;17:332 Arylnapthalene derivatives 24:762-775 synthesis of 24:761,766 3-Aryloxy-6,7-dihydroxycoumarin 30:220 Arylpropanoid 30:213 reaction of 30:213 Arylpyruvic acids 30:220 Aryltetrahydronaphthalene lignans 26:193 Aryltetralin lactone 30:570 Aryltetralin lactone-type lignan 30:586 Aryltetralin lignans 26:195,196 trans-Aryltetralinlactone type lignans 26:154 Aryltetralins 17:341,343;24:742 as anti-HIV agents 24:742 [3-Aryl-f3-methylacrylates 12:462 Arynes 3:418-421,422-454 as EBV inhibitor 30:592 generation of 3:418-421,422-454 nucleophilic additions of 3:418, 421-437 Asadanin I & II 17:369 Asarinin 26:226,231 (-)-Asarinin 26:260 (+)-Asarinin 26:267 8-Asarinin 5:753,754 Asarone 22:510,537
a-Asarone 26:470 ~-Asarone 22:510;26:470 Asarum maranthuym 22:513 for hysteria 22:513 Asatone 8:168 Asbcisic acid 2:164 Ascaridia galli 26:457,484 Ascaridole 20:13;26:431 Ascaris lumbricoides 23:837;26:425,429 Ascaris sp. 26:463,478 Ascaris suilla 26:443 Ascaris suum 26:443,450,477 Asci 22:247 Ascidia mentula 28:642 heneicosane- 1,21-diyl disulfate from 28:642 3,7,11,15tetramethylhexadecane1,19-diyl disulfate from 28:642 Ascidia nigra 10:241 ;23:242 Ascidiacyclamide 4:91-93;5:419,420; 10:242;25:879 Ascidian alkaloids 25:706 Ascidian metabolites 25:758 Ascidian tyrosine 23:241 Ascidians 23:233-283;25:707,709 aromatic alkaloids from 23:233- 283;25:707,709 Ascididemnin 23:274 Asclepiadaceae 5:751 ;18:649 Asclepias curassavica 5:249 Asclepias fruticosa 5:248,249 Asclepidaceae sp. 27:3 Ascobolus furfuraceus 5:279;21:209, 228,235 Ascochyta viciae 21:227;26:797 Ascocoryne sarcoides 29:266 Ascocorynin 29:266,296 biosynthesis of 29:296 inhibition of gram-positive bacteria by 29:266 synthesis of 29:299 Ascofuranone 26:797 Ascomycetes 9:202,203;22:460;25:129 Ascomycota sp. 22:246 Ascomycotina 9:202 L-Ascorbic acid 13:70
74 Ascorbic acid 21:503;25:236,349,930, 936;27:747 Ascorbic acid analogue 30:224 2-hydroxyfuran-2-one as 30:224 Ascosalipyrrolidinone A 28:148 against antibacterial activity of 28:148 against chloroquine-resistant Plasmodium falciparum 28:148 against Trypanosoma brucei 28:148 against Trypanosoma cruzi 28:148 Asebotoxin 20:17 Asernestioside A 25:195 Asernestioside B 25:195 Asernestioside C 25:195 Ashurbin 7:233 Asiasari radix 21:378 Asiasarum heterotropoides 21:378 Asiasarum hetrotropoides vat. madshuricum 24:228-232;26:212, 226 asarinin from 26:212,226 xanthoxylol from 26:212,226 Asiasarum sieboldii 21:378 Asiatic acid 25:541 Asiaticoside 15:213 Asimicin 9:391,392,396;26:441 Asimicin triacetate 9:391 ;17:262 Asimilobine 21:68;22:22;25:531 Asimina tiloba 9:391 Asinger condensation 12:127,129 Askendoside A 25:198 Askendoside B 25:194 Askendoside C 25:198 Askendoside D 25:194 Askendoside G 25:198 Aslcaligenes eutrophus 25:162 Aslchyta rabiei 26:1288 Asttonia macrophylla 13:383,422 Asltonia muelleriana 13:383,399,422 Asocainol 6:478 Aspalathus linearis 28:272 Asparaginase 25:719 Asparagine 26:1131 Asparagine acid 21:738 Asparagopsis sandfordiana 9:83-85 marine sterols from 9:83-85
Asparagus africanus 26:230,813 Asparagus cochinchinensis 17:116-117, 130.132
Asparagus curillus 7:427 Asparagus officinalis L. 21:636,662; 22:513;25:377;26:477
Asparagus plumosus 7:427 Asparagus racemosus 22:513 as anticonvulsant in epilepsy 22:513 for epilepsy 22:513 Asparagus sp. 17:130;25:37 Asparagusic acid 26:477 Asparenomycines 4:434 in carbapenems 4:434 Aspartate 21:10,14;30:836 c~2-macroglobulin inhibition by 30:836 Aspartate transaminase 21:655;25:477 L-Aspartic acid 6:263;12:160;13:63 4-acetoxy-[3-1actam from 12:160 Aspartic acid 21:214,738 Aspartic proteases 25:330,331,375; 29:568 as inactive zymogens 29:568 chymosin as 29:568 gastricsin as 29:568 haemoglobinases of Plasmodium falciparum as 29:569 immunodeficiency virus 1 (HIV1) protease as 29:569 in Alzheimer's disease 29:569 non-protein inhibitors of 29:570 overexpression of 29:569 pepsins as 29:568 [3-secretase as 29:569 N-Aspartyl-pseudodisaccharides 13:218 Asperdiol 10:18 activity against lymphocytic leukemia 8:15 growth inhibition of KB, PS and LE Cell lines 8:15 Asperentin 15:382,385-387 Asperger's syndrome (AS) 30:372,373, 384 form of autism 30:373 Aspergillimide A 26:491 Aspergillimides 26:491
75 Aspergillosis 2:422,425 Aspergillus aculeatus 23:343 Aspergillus acylase 1:678 Aspergillus alleaceus 20:792 Aspergillus arenarius 29:282,292 Aspergillus awamori 2:322,341,353 Aspergillus brevipus 12:400 Aspergillus caespitosus 19:480 Aspergillus campestris 29:269,281 Aspergillus candidus 29:267,268,270, 281 Aspergillus cellulosae 25:150 Aspergillus cladosporoides 26:228 Aspergillus clavatus 21:240 patulin from 21:240 Aspergillus deflectus 23:343 Aspergillus duricaulis 15:343,345 Aspergillus flavus 2:446;5:296;9:300; 15:386,245;18:711 ;26:228;27:225, 382;28:128,476 Aspergillus fumigatus 5:295-298,322, 326;7:65 ;9:300;12:400;18:469,807, 809;21:237 ;22:261 ;23:4,5 ;25:764; 26:228,458,673,1093,1128 helvolic acid from 21:237 Aspergillus melleus 15:383;21:211; 26:449 Aspergillus nidulans 5:295,296;21:188; 22:263,476;23:240;25:301,321 Aspergillus niger 21:217,240,396,599; 22:627;23:349;25:136,140-143,145, 148,149,152-155,157,158,165,166, 168,172,173,777;26:228,307,971,11 41,1144,1263,1268,1278,1280,1283, 1286,1287 ;27:382 ;28:476;29:548; 30:431,739 cz-L-rhamnosidase from 7:70 [3-glucosides from 7:51,52,55, 56,65-67 antibacterial activity against 30:739 antifungal activity against 30:739 cycloisomerase from 8:296 3-deoxy-2-keto-gluconate (KDG) aldolase from 30:431 glucoamylase from 7:62 isozyme I from 2:322,341
lactone from 8:300 metabolic function of 30:431 Aspergillus nomius 28:128 Aspergillus ochraceus 15:387;21:211; 25:139;27:382 ochratoxins from 15:387 Aspergillus oryzae 1:697,117;2:322, 341 ;5:295 ;6:551,552 ;13:304 ;21:238; 25:780;26:1007 Aspergillus parasiticus 22:266;27:382; 28:128 averufin by 11:194 Aspergillus sp. 2:323;5:276,278,294, 301,325,5:326,328,368,370;9:203, 300;21:196,204,233,239;22:57,248, 251 ;25:150,151,156,729;26:450,491 glucoamylase from 2:322 Aspergillus stellatus 10:439 (+)-asteltoxin from 10:439 Aspergillus taichungensis 29:269 Aspergillus tamarii 28:128 Aspergillus terreus 5:296,730;15:385; 19:168;21:212,233,240,239;22:627; 26:1281 ;30:220,431 patulin from 21:240 butyrolactone II from 30:220 Aspergillus versicolor 18:807,809 Aspergillus wentii 7:56,64;9:300; 28:454,465 Asperline 15:350,351;19:463 Asperula sp. 26:631 Asperuloside 7:439,455,469,470,479, 480;16:298;26:666 Asperulosidic acid 26:666 Asperulosidol 7:467,468 Asphaenogaster rudis 5:226,243-245 Aspiculamycin 4:242;26:493 Aspicularis tetraptera 26:493 Aspidosperma 19:114-115 Aspidosperma cyclindocarpon 19:112 Aspidosperma indole alkaloids 13:70,93 Aspidosperma marogravianum 1:124 Aspidosperma oblongum 1:124,125 Aspidosperma olivaceum 26:144
Aspidosperma quebrachoblanco
Schlecht 29:362 Aspidospermatan-type alkaloids 1:31, 32;5:71,86,87,135 Aspidospermatidine 1:40
76
Aspidospermidine 13:93;14:632-636; 26:140 (-)-Aspidospermidine 19:143 Aspidospermidine N- 14,15-methyl14,15-oxido 5:126 Aspidospermidose fi: 165-167 Aspidospermine alkaloid 18:338 Aspirin 30:192,195,594 AA-induced platelet aggregation inhibitor 30:594 as cyclooxygenase enzyme (COX) inhibitor 30:192,594 platelet aggregation role of 30:594 structure-activity relationships of 30:195 Aspochalasans 13:108,131,134 Aspochalasin B 13:142,143 Aspochalasin C 13:108,131,134 Aspochalasins 15:355 Aspterric acid 5:729,730,732,733; 21:232 Aspyrone 21:211;26:449 Assay 25:373;30:833,835 absorbance in 30:835 chromophoric oligopeptides in 30:835 chromophoric procedure in 30:835 for systemin activity 25:373 of EFE 30:835 of isozymers 30:833 ofLumbricus rubellus 30:833 scattering intensity in 30:835 Assay method 25:100 for hepatoprotective effects 25:100 Astaxanthin 6:153;20:577,578,588, 607;21:298,299,304,305;30:518,520, 533,538,543 course of formation of 30:543 radicals cations of 30:538 (3S,3'S)-Astaxanthin 6:158;7:361,362 (3R,3R)-Astaxanthin 7:321,361,362 (+)-Asteltoxin 10:439-442 absolute stereochemistry of 10:439,440 Claisen rearrangement by 10:439-442
from Aspergillus stellatus 10:439 synthesis of 10:439-442 Asteltoxin 16:670 from Aspergillus stellatus 16:670 Aster batangensis 21:673 asterbatanoside F from 21:673 Aster saponin A 15:209 Aster saponin H 15:210,211 Aster spathulifolius 25:251 Aster tataricus 24:339 Asteraceae 21:97;22:396;25:235,249, 250,252,944 ;30:704 as medicinal plants 30:704 in folk medicine 30:704 Asteremyces cruciatus 25:828 Asteria pectinifera 7:307 Asteriarubin 6:162;30:533 from Asterias rubens 6:161 Asterias amurensis 7:286-298,303; 15:44 Asterias amurensis vesicolor 7:287 asterosaponin-i from 7:287 thornasteroside A from 7:287 versicosides (A-C) from 7:287 Asterias forbesi 7:288;15:58,69;28:718 Asterias rubens 6:151,152,156,161; 7:288,294,304,306;15:48 Asterias vulgaris 7:288,291,304;15:59; 28:718 Asterina pectinifera 7:289;15:44,48,55; 25:698 Asterinic acid 6:161 Asterogenol (20R-5c~-pregn-9(11)-ene3~,6c~,20-triol) 7:288,291 Asteroidea 7:265,285-307;15:43-45 Asterone 15:45 Asterone (3[3,6~-dihydroxy- 5ot-pregn9(11)-en-20-one) 7:290,291 (+)-Asterosaponin 7:285,288,290,291, 294,7:303,304 Asterosaponin 1 (forbeside C) 7:287, 288,293 Asterosaponin A and B 7:286,303 from Asterias amurensis 7:286,303
77 Asterosaponin D1-D3 7:299,302,303 biosynthesis of 7:299,302,303 from Distolasterias nipon 7:299 Asterosaponin P~ 7:297,300 from Oreaster reticulatus 7:297,300 Asterosaponins 15:45-58 Asterosides A-D 7:287,293 Asthma 30:70,225 treatment of 30:225 Astichoposide C 7:273,281,282 from Astichopus multifidus 7:273 Astichopus multifidus 7:272,273,281 astichoposide C from 7:273 Astilbe chinensis 27:395 Astilbejaponica 27:395 Astilbe revularis var. rivularis 27:395 Astilbe thunbergii 27:395 Astilbin 27:395 structure of 27:396,397 Astins 24:339 Astiraversianins 25:179 Astrachyside A 25:194 Astracicerans 256 27:498 Astragali radix 27:443,445,507,513 activity of 27:513 Astragali semen 27:478 Astragalin (kaemp ferol-3- O- [3-Dglucoside) (flavonol glycoside) 29:578 effects on ACE 29:578 Astragalloside 25:104 Astragallus genus 25:188,190 Astragallus sp. 25:180,183,186,187, 190,219;27:253 Astragaloside 25:179 Astragaloside I 25:193,224,227 Astragaloside II 25:193,220,221,223, 224,227 Astragaloside III 25:194 Astragaloside IV 25:193,220,221,224, 226,227 Astragaloside V 25:195 Astragaloside VI 25:194,224,227 Astragaloside VII 25:194 Astragaloside VIII 25:95,115,116,118, 120,203,222 Astragaluquinone 27:505
Astragalus adsurgens 25:184;27:478, 450
Astragalus aitosensis M.B 27:449,450, 511
Astragalus alexandrinus 25:184,189,
192,193,214,224 ;27:454,476,477, 500,505 Astragalus alopecuros 25:184,201; 27:449,452 Astragalus amarus 25:194,195 Astragalus angustifolius 27:466 Astragalus babatagi 25:184 Astragalus basineri Trautv. 25:184,194 Astragalus bethlehemiticus 25:188,189 Astragalus bisulcatus 27:516,527,528 Astragalus boeticus 25:192 Astragalus brachycentrus 25:184,192, 193,197;27:454;30:405,411 antiviral activity of 30:405 Astragalus bungeanus Boiss 27:453 Astragalus canadensis L. 27:444,522 Astragalus caryocarpus 27:444 Astragalus centralpinus 27:505 Astragalus cephalotes 25:184,197; 27:454,455 Astragalus collinus 27:522 Astragalus coluteocarpus 25:184,192 Astragalus complanatus 25:93,184, 203,204;27:445,453,477,478,481; 27:453 Astragalus convallarius 27:525 Astragalus crotolariae 27:528 Astragalus da~yanthus Pall. 27:451 Astragalus dissectus 25:184,192; 27:440,449 Astragalus echianaeformis 27:514; 30:405,411 antiviral activity of 30:405 tragacanthin polysaccharide (PS) from 30:411 Astragalus edulis 27:444 Astragalus emoryanus 12:313 (-)-swainsonine from 12:313 Astragalus ephemerotum 25:184;27:449 Astragalus ernestii 25:184,195 Astragalus exilis L. 25:184 Astragalus falcatus 25:196;27:511 Astragalus flexuosus 27:522 Astragalus floccosifolius 27:504
78
Astragalus furcouga 25:472 Astragalus galegiformis L. 25:184,196; 27:450,470
Astragalus genus 27:470,523 Astragalus glycyphyllos L. 25:184,203; 27:444,453,466,477
Astragalus gummifer 25:188;27:444, 499,511
Astragalus hamosus L. 25:184 Astragalus illiensis L. 25:184,195 Astragalus kahiricus 25:189 Astragalus kuhitangi 25:184,192,194; 27:455
Astragalus kulabensis 25:184;27:449 Astragalus kurdicus 27:511 Astragalus L. genus 27:443 biological activity of 27:443
Astragalus lasioglottis 27:505 Astragalus lentiginosus 7:11,486;
27:251,515,524,517 (-)-swainsonine from 12:313 Astragalus lusitanicus 27:524 Astragalus melanophrurius Boiss 25:184,192,25:193,194,197 ;27:455, 482 Astragalus membranaceus 27:482 antiviral activity of 27:482 Astragalus membranaceus Bunge 22:97;24:145;25:184,192,193,194, 195,200,205,219,220,221 ;27:443, 445,450,467,468,505,511,446,468, 470,481-483,500,506,508,513,665 Astragalus miser 27:525 Astragalus miser var. oblongifolius 27:519 Astragalus miser var. serotinus 27:521 Astragalus mollissimus Torr. 27:444 Astragalus mongholicus Bunge 25:184, 192,193,194,202,219;27:448,454, 467,503,504,508,511 Astragalus oleifolius DC 25:185,199; 27:448 Astragalus onobrychis 27:453,466,504, 480 Astragalus orbiculatus 25:185,202; 27:452,515 1-hydroxyindolizidine from 27:515
1,2-dihydroxyindolizidine from 27:515 Astragalus pamirensis 25:185,192,197, 200,202,203 ;27:449 Astragalus pattersonii 27:528 Astragalus pectinatus 27:528 Astragalus penegrinus Vohl 25:185, 195,216,225 Astragalus polycanthus 27:517 Astragalus praelongus 27:516 Astragalus pterocarpus 25:185,192, 193;27:525 Astragalus pterocephalus 27:449 Astragalus pycnanthus 25:185,193, 198;27:450 Astragalus quisqualis Bunge 25:185; 27:450,504 Astragalus racemosus 27:528 Astragalus root 27:445 medicinal use of 27:445 Astragalus severtzovii 27:478 Astragalus shikokianus 27:453 Astragalus siculus 27:482 Astragalus sieberi 27:470 Astragalus sieversianus 27:449,478, 480,481,483 Astragalus sinicus 27:453,511 Astragalus spinosus 21:664;27:468,483 astragaloside II from 21:664 Astragalus spp. 7:23;25:179;27:253, 454-465,474,478,483,498,500,503, 511,519,520,521,523,745 activity of 27:483 biological activity of 27:443 of Leguminosae 27:519 of saikosaponin 27:671 Astragalus subrobustus 27:504 Astragalus tashkendicus 27:454 Astragalus tibetanus 27:517 Astragalus toanus 27:516 Astragalus tomentosus 27:451,473 Astragalus tragacantha Habl. 27:448, 454 Astragalus trigonus DC 27:448,500,505 Astragalus trojanus Stev. 27:453,454, 479 Astragalus wootoni 27:516 Astragersianin VII 25:193 Astrailienin A 25:195
79 Astramembranin I 25:193,220 Astraverrucln I 25:194 Astraverrucln II 25:194 Astraverrucln III 25:194 Astraverrucln IV 25:195 Astraverrucm V 25:195 Astraverrucln VI 25:195 Astraverslanm I 25:193 Astraverslanln II 25:193,224 Astraverslanln IV 25:193 Astraverslanm IX 25:194 Astraverslanm V 25:193 Astraverslanm VI 25:193,224 Astraverslanm X 25:192,224,227 Astraverslanm XI 25:194,226 Astraverslanln XII 25:195 Astraverslanln XIII 25:195 Astraverslanln XIV 25:193,194,224 Astringent 5:751,754 Astringent agent 23:642 of teucrium sp. 23:591 Astrocytes 30:367 Astrojanoside A 25:203 Astropecten aurantiacus 15:104;15:61 Astropecten indicus 5:214;7:299 Astropecten latespinosus 7:288;15:48 Astropecten polyacanthus 7:306;18:725 Astropecten scoparilis 15:68 Asuka-mABA 21:401 Asukamycin 11:189;23:92 Asukamyene 21:398 Asymmetric 11:367 alkylation 11:367 base (LDA) mediated 10:408,409 catalytic epoxidation 11:431, 432 catalytic osmylation 11:431,432 cycloaddition 11:358 dihydroxylation of 11:423,424 diastereoselective 14:491-499 enantioselective 10:412 in basic media 4:389-391 intramolecular 16:125;19:486 of (-)-arctigenin 24:749 of (S)-c~-terpinylamine 11:283 of 1,5-acetyl- 1-thiohex-2enopyranosides 10:342 of 1-benzyl-2,6-dicyanopiperidine 6:433
of 1-phenyl- 1-methyl 6,7 seleno1-ethyllithium 8:6,7 of 2-acetoxy-5,6-dihydro-2Hpyrans 10:342 of acetals 1:613-616 of benzyllithium 8:6 of carbanion 8:176 of carvone 10:408,409 ofchiral acetals 12:489-493 of cyanohydrin 8:16 of cyanohydrin ethers 8:177-179, 183 of dianion 11:284,285 of dimethyl malonate 8:185,186 of dioxolane enolates 1:644 of (-)-dimethyl matairesinol 24:749 of (-)-enterolactone 24:749 of (-)-hinokinin 24:749 of (-)-kusunokinin 24:749 of (-)-yatein 24:749 of FAMSO 6:313 of fluoromalonate 13:82 of methylmalonate 13:79 of MT-sulfone 6:334 of N-nitrosopyrrolidine 6:439,441 of silver cyanides 12:113 of sulfur stabilized carbanion 8:16 of trans-2,5-bis (methoxymethoxymethyl) pyrrolidine 10:412 of w-haloalkylphenylthioacetate 8:176 of et-methyl-phenylacetic acid 10:412 of c~-phenyl-?,-lactone 10:410, 411 of ~-ketoester 8:181,191 palladium-mediated 16:422 regioselective 10:342 stereoselective 10:342,410,411; 11:284,285 synthesis of 3:166,167 TiCI4 catalysed 1:615 trans-stilbene 11:423,424 via sequential dianion generation
80
16:371 with 1-TMS-2-pentyne 11:284, 285 with 2,5-dibromo-2-methyl pentane 8:6,7 with 3-butynyl p-toluene sulphonate 14:559 with allylic halide 8:178 with benzyloxymethyl chloride 6:561 with di-t-butyl dicarbonate 14:559 with House procedure 10:308, 309 with indole-protected tryptophyl bromide 11:283 with organometallic reagents 1:613-616 Asymmetric [3+2] dipolar cycloaddition 13:500 Asymmetric 1,3-dipolar cycloaddition 1:371-375 Asymmetric additions 4:332 to prochiral carbonyl groups 4:332 to prochiral naphthalene rings 4:332 Asymmetric aldol condensation 12:162; 13:63 Asymmetric aldol methodology 21:438 Asymmetric alkylation 10:411 of methylmalonic acid 10:411 of (-)-phenylmenthyl ester 10:411 Asymmetric allylboration 8:477,478 Asymmetric aza-annulation reaction 18:378,379 Asymmetric bromolactonization 4:338, 339 with acetals from tartaric amides 4:338,339 with N-bromoacetamide 4:338, 339 with chiral acetals 4:338,339 with unsaturated (S)-proline amides 4:336,337 Asymmetric carbocyclization 6:62,63 in (-)-2R,6S,8S,9S)-2,8-dibromo-
9- hydroxy-ot-chamigrene synthesis 6:62,63 Asymmetric catalysts 17:323 hydrogenation of 17:323 synthesis of 17:479 Asymmetric cyclization 10:611, 631-633;14:506,507 biomimetic 14:506,507 of chiral acetal 14:506,507 Asymmetric cyclopropanation 14:488 with methyl carbenoid 14:488 Asymmetric Diels-Alder reaction 8:139-157 at chiral auxiliaries 4:607 in prostaglandin synthesis 4:607 in tetramycin synthesis 4:607 using chiral boron reagent 4:609 in [3-santalene synthesis 4:607 Asymmetric Diels-Alder technology 13:602 Asymmetric dihyroxylation 11:60; 19:269-270,274,278,284 Asymmetric dimethylation 10:412-415 Asymmetric epoxidation 4:172-174; 10:561;12:323 of (+)-N-benzyloxycarbonyl-3hydroxy-4-of allylic alcohols 4:172-174;10:561 ;12;323 ofpentenylamine 12:281 of swainsonine 10:561 Asymmetric esterification 9:25 Asymmetric hydration 13:71 ofalkenes 13:71 Asymmetric hydroboration 8:473,474, 478;13:71,72 Asymmetric hydrogenation 12:162; 16:411;24:749 BINAP-Ru-catalyzed 4:439 of[3-keto esters 4:439 Asymmetric hydrolysis 1:684,685 by esterases 1:684,685 by lipases 1:684,685 of N-acetyl (x-amino acids 1:678,679 Asymmetric hydrosilylation 13:72 intramolecular 13:72 Asymmetric hydroxylation 9:572 of pentadienols 9:572
81 Asymmetric induction 10:412; 12:153, 156;14:471,507,508,524,553 1,2-Asymmetric induction 11:231-238 1,4-Asymmetric induction 12:156 1,5-Asymmetric induction 14:499 1,3-Asymmetric induction 14:529,552 1,6-Asymmetric induction 14:530 1,4-Asymmetric induction 4:203,495 Cram's cyclic model of 4:203, 495 in (-)-piperitone 6:15 in aza-annulation reaction 18:373-386 in dienolate addition 3:47 in diyl trapping 3:20 in Ireland-Claisen rearrangement 3:237 reversion using sulfoxides 4:511 self-immolative 3:237 with chiral auxiliaries 4:499-517 Asymmetric ketoester cyclization 4:328-330 Asymmetric metallation 14:511 of chiral arylaldehyde acetal chromium tricarbonyl complexes 14:511 Asymmetric Michael addition 4:501, 502 in estrone synthesis 4:501,502 Asymmetric osmylation 19:269 Asymmetric oxidation 14:517,518 ofprochiral sulfides 14:517,518 of sulfide 4:489 sulfoxides from 14:517,518 with chiral sulfamyloxaziridines 4:489 with chiral titanium complexes 4:489 Asymmetric quaternization 10:426-428 by Claisen rearrangement 10:426-428 by consecutive alkylation 10:405,406 of aldohexofuranose derivatives 10:428-432 of m-carbon of y-lactones 10:405 Asymmetric reduction 10:410 by Baker's yeast 10:410
of acetoacetic acid ethyl ether 10:410 of acetylenic ketone 11:424 of acyclic ~-hydroxy ketones 14:183,184 of~-keto esters 14:533,534 with Baker's yeast 1:689 with Ipc2BH 8:476 Asymmetric synthesis 24:744-754,761, 766,767,772,773,775,777,780,781 by diastereofacial selection 13:62-70 by enantiofacial selection 13:70-73 by enantiotopic discrimination 13:60-62 of (+)-azaisopicrostegnane 24:775,777 of conidendrin 24:772,773 of 2,3- dibenzylbutyrolactones 24:744-754 of(+)-gomisin A 24:775-777 of (+)-isolarresinal 24:767 of (+)-isoschizandrin 24:775,777 of (-)-isoschizandrin 24:780,781 of (+)-paulownin 24:761,766 of (-)-podophyllotoxin 24:767, 775 of (+)-schizandrin 24:775-777 of (-)-schizandrin 24:780,781 of paraherquamide A 28:331,367 of carbaoxirose/carbaoxetoses 29:490 of (-)-ajmalicine 14:563,564 of (-)-sibirine 14:539-544 of (+)-(S,S)-solenopsin A 6:431, 432 of (+)-castanospermine 12:346 of(+)-elaeokanine A 12:351,352 of (+)-elaeokanine C 12:351,352 of (R)-muscone 14:490 of (R/S)- 1,6-dioxaspiro [4.5] decane 14:523,524 of (R/S)- 1,7-dioxaspiro [5.5]undecane 14:521-526 of[m, n, 1] propellanes 14:490 of 2-deoxy-D-arabino-hexose 14:176,177 of 3-deoxy-D-ribo-hexose
82
14:176 of 4-acetoxy-3-[ l'-(tertbutyldimethyl-silyloxy) ethyl]azetidinone 4:448 of 4-deoxy-D-lyxo-hexopyranose 14:176 of 5,1-1inked naphthylisoquinoline alkaloids 20:420-438 of 5,8-1inked naphthylisoquinoline alkaloids 20:442-451 of 7,1-1inked naphthylisoquinoline alkaloids 20:438-441 of anthracycline antibiotic 14:492,493 of azetidinone 4:448 of buphanisine 4:14,15 of chiral alkaloids 10:671-689 of chiral building blocks 14:551-581 ofchiral isoquinolines 10:671 of chiral piperidines 10:671 of crinine 4:14,15 of desoxydaunomycinone 14:23 of indolizidine alkaloids 6:442, 443 of monomorine I 6:449,450 of pyrrolidine alkaloids 6:442, 443 ofpyrrolizidine alkaloids 6:442, 443 of R,S-4-hydroxycyclopentenones 6:315 of solamin 18:202-206 of talaromycin A and B 14:531-539 propane-l,3-diols by 13:53-105 via chiral organoboranes 8:465-478 with chiral sulfur reagents 10:671-689 Asymmetric transformation 13:77 crystallization-induced 13:77 of malonic acid derivative 13:88 Asymmetrization 11:241,242 of cy-symmetric ketones 11:241, 242 AT2433-AI 12:366,368 from Actinomadura melliaura 12:366,368
AT2433-A2 12:366,368 from Actinomadura melliaura 12:366,368 AT2433-BI 12:366,368 from Actinomadura melliaura 12:366,368 AT2433-B2 12:366,368 from Actinomadura melliaura 12:366,368 Atalantia ceylanica 13:348,349,356 1,5-dihydroxy-3-methoxy- 10methylacridin-9-one from 13:348,350 11-hydroxynoracronycine from 13:348,349,356 11-O-methylatalphilidine from 13:348,349 N-methylatalphyllinine from 13:348,349 Atalantia monophylla 13:348-350 atalphyllidine from 13:348,349 atalphylline from 13:350 atalphyllinine from 13:349 N-methylatalphylline from 13:350 Atalfoline 13:350 from Citrus buxifolia 13:350 Atalphyllidine 13:348 from Atalantia monophylla 13:348 Atalphylline 13:350 from Atalantia monophylla 13:350 Atalphyllinine 13:348,349 from Atalantia monophylla 13:348,349 Athanasin 16:666 from Athanasia L. 16:666 Atherosclerosis 11:335;12:399;22:310; 23:470,766;25:934 ;30:224 development of 23:766 of S-allyl cysteine (SAC) 23:470 role of free radicals in 30:224 Ent-Atis-16-ene-3,14-dione 9:68,269, 276,277,279,290 Atisane 25:241 Atisane diterpenoids 9:267-281 EntAtisane ent- 16c~,17-dihydroxyatisan-3one 29:100
83 activity in mam-2 assay system 29:100 Ent-Atisanes 9:267-283 Atisense RNA 13:257-261 gene expression by 13:257-261 natural regulation of 13:257-261 Atisine 3:435;26:868 synthesis of 3:435 Atisirene 10:180 synthesis of 10:180 Atmospheric pressure chemical ionization 21:555 Atomic orbital coefficients 4:586 in Diels-Alder reactions 4:586 Atopic dermatitis 30:70 Atovaquone 26:840 H+,K+-ATPase 21:690,701,702,717,719 inhibitory effect on 21:701,719 ATPase activity 21:137 Atractylis gummifera 20:8 Atractylodesjaponica 29:88 Atractylodes lancea 24:877,878,883, 29:694 Atractylon 29:88 activity in TPA, skin-1 assay systems 29:88 Atractyloside 20:8 Atrazine 25:669 Atrial natriuretic factor (ANF) 25:519, 540,547 Atrial natriuretic peptide 27:870 Atromentin 29:271,296 against Bacillus subtilis 29:272 antibacterial activity of 29:271 as anticoagulant principle 29:271 biosynthesis of 29:296 Atropa belladonna L. 20:135;22:721, 734,742,8 Atropa genus 17:395 Atropa sp. 21:104,488 Atropine 21:488;22:735 Atropine (DL-hyoscyamine) 22:19 Atropisostreptovaricin C 23:65 Atropisostreptovaricin Fc 23:65 2-ATT (2-acetylthiazole) 11:443,444 Atta cepholotes 22:66 2,5-dimethyl-3-ethyl-pyrazines of 5:222
Atta sexdens rubropilosa 5:222;26:186 2,5-dimethyl-3-ethyl-pyrazines of 5:222 Atta sexdens sexdens 5:222 2,5-dimethyl-3-ethyl-pyrazines of 5:222 Atta texana 5:234,125 [3-Attantone 23:830 Attanuatoside C 7:295,296,300 Atta-ur-Rahman synthesis 14:850 of (+)-16-hydroxydihydrocleavamine 14:850 of (+)- 16-methoxycarbonyldihydrocleavamine 14:850 of (+)-coronaridine 14:850 of (+)-dihydrocatharanthine 14:850 of (+)isovincadifformine 14:850 of (+)-c~-dihydrocleavamine s 14:850 of (+)-[3-dihydrocleavamine s 14:850 of anhydrovinblastine 14:857 of vinblastine 14: 850-859 of vincristine 14:850-859 Attenuatodside 7:295 from Hacelia attenuata 7:295 Attenuatoside A-1 7:295-297,299,300 Attenuatoside A-II 7:295,296,300 Attenuatoside B-I 7:295,296,300 Attenuatoside B-II 7:295,296,300 Attenuatoside C 15:61 from Hacelia attenuata 15:61 Atuna racemosa 29:708 Aucubigenin 7:478 Aucubin 7:440,455,465,472,473,476, 478,479,480,481-483 ;29:84 activity in TPA assay system 29:84 6-epi-Aucubin 7:472,473 Auguidine 6:225,226,229 Augustilobine A&B 9:171 Aulacocarpin A 23:799 Aulacocarpin B 23:799 Aulacocarpines A & B 25:259 Aulacocarpinolide 23:799;25:259,266 Aulacophora femoralis 23:66
84
Aulacophora femoralis chinensis 18:771 Aurainvilleol 25:787 (+)-Auranthioclavine 16:438 synthesis of 16:438 Aurantiamide acetate 7:220 from Artemisia anomala 7:220 Aurantinin 5:601,603 Aurantinin A 5:601,604-607 Aurantinin B 5:601,603-606 Aurantoside A 25:763,793;26:1176, 1179 Aurantoside B 25:763;26:1176,1179 Aurantoside C 25:793 Aurantoside F 25:763 Aurantosides 25:757,763 Aurapten 20:497 from Limonia acidissima 20:497 AURELIA 23:30 Aureobasidin A 23:343 Aureobasidin A insitol 22:248 phosphyorylceramide 22:248 Aureobasidins 22:248 Aureobasidium pullulans 5:307,308, 314;21:396;22:248;23:343 Aureobasidium sp. 5:307 Aureol 5:430,431,437,438,444;9:31,32; 15:300,314 Aureolic acid antitumor antibiotics 3:173-206 Aureolic acid 3:173-175 Aureomycin 25:757 Aureothin 5:551 Auricularia auricula-judae 5:290,316, 318,319,733 Auricularia sp. 5:287,317,320 Aurilol 25:763 Auriside 25:757 Auriside A 25:762;27:789 Auriside B 25:762;27:789 Auristain 25:716 Aurones 7:192;22:420;26:744,801; 27:893 Ausantoside E 25:780 (-)-Austalide B 18:32 from Aspergillus ustus 18:32 Austalides A-F 18:32,37 Australine 7:13;10:567;22:183 amyloglucosidase inhibitor of
7:13;10:567 from Castanospermum australe 7:13;10:567 ~-glucosidase inhibition by 7:11 glucosidases I,II inhibition by 7:13 oligosaccharide chain inhibitor 10:567 Austrobailignan-1 26:193 Austrocedru chilensis 19:405 Austrovenus stutchburgi 25:864;28:656 brevetoxin BI from 28:656 Autism 30:368,371,374,375 as neurodevelopmental disorder 30:371 brain parts affected by 30:375 etiology of 30:368 genetic component to 30:375 impairments in reciprocal social interaction in 30:368 in dizygotic (DZ) twins 30:371 in monozygotic (MZ) 30:371 incidence of 30:374 pathogenesis of 30:368 prevalence of 30:374 restricted pattern in 30:368 role ofamygdala in 30:375 role of serotonin (5-HT) 30:368 stereotyped pattern in 30:368 symptoms of 30:371 with multiple etiologies 30:371 Autistic brain 30:376 neuropathological studies of 30:376 Autistic children 30:375,377 cerebellar hypoplasia in 30:375 signal reception in 30:377 Autistic disorder 30:372 diagnostic criteria for 30:372 Autistic features 30:374 in alcohol consumption 30:374 in congenital cytomegalovirus 30:374 in fragile X syndrome 30:374 in hypothyroidism 30:374 in matemal thalidomide 30:374 in phenylketonuria 30:374
85 in rubella infections 30:374 in tuberous sclerosis 30:374 Autistic individuals 30:375 Autistic spectrum disorders 30:374 neurochemical pathway of 30:374 Autoimmunodeficiency syndrome 18:908 Automated synthesis 13:257-294 of oligonucleotides 13:257-294 of oligodeoxyribonucleotides 4:280 reaction cycle 4:281 Automatic DNA synthesizer 4:304 Autooxidation 14:335,336 of 1-methylazulene 14:335,336 ofbenzylic positions 16:571 of guaiazulene 14:316-319 ofphenylhydrazine 9:581 Autoradiographic imaging 30:377 serotonergic innervations in 30:377 Autotoxic effects 28:537 of NO on tumor cells 28:537 Auxarthron unberium 25:794 Auxiliary enolate 21:231 Auxins 17:424;25:367,379,652,656, 657;26:581 effect on root culture growth 17:424 indoleacetic acid as 7:90 naphthalene acetic acid as 7:90 Avarol 5:430,431,438,439;9:30,31; 15:238,252;21:252;25:697;29:111 activity in CRG bioassay system 29:111 activity in TPA bioassay system 29:111 Avarol monoacetate 15:300 Avarone 5:430,431,434,438,439; 15:301,314;21:252;25:697;29:111 activity in CRG bioassay system 29:111 activity in TPA bioassay system 29:111 2-AVD treatment 25:462 Avena fatua L. 27:215-217,218 allelopathic interaction of 27:215
Avena sativa 9:220;23:341;27:216-218 allelopathic interaction of 27:216 Avena strigosa L. 27:215 allelopathic interaction of 27:214-218 Avenacin A-1 25:304-306,314 Avenacinase 25:304-306,308 Avenaciolide 3:259,260;19:485 Avenalumin I 23:341,348 Avencins A1,Az,BI,B2 7:136,137 Avenestergenins A1,Az,BI,B2 7:136,137 Average mass 2:26 Avermectin 12:13,709;26:425,426,442, 453,494 biological activity of 12:709 structure-activity relationship of 12:8 Avermectin A 12:3 Avermectin A~a 12:12,13,15 Dainshefsky synthesis of 12:12,13,15 from D-robosa 12:12,13 from Streptymyces avermitilis 12:6 Avermectin B 12:3 Avermectin B~ 12:9 insecticidal activity of 12:9 Avermectin B~ 1:463-465 synthesis of 1:463-465 Averrhoa carambola 22:359;23:785 Avian hemoglobin 5:849 alkaline denaturation 5:841 allosteric regulator binding sites 5:849 amino acid composition 5:841 carbon dioxide transport 5:853 electrophoretic mobilities 5:839841 heme binding sites 5:869 heterogeneity in 5:856 inositol pentaphosphates in 5:857 oxygen affinity 5:856 oxygen uptake 5:853 physiology 5:854-859 primary structure 5:844-850 structure of 5:835-850 Avicennia alba 7:176,181,182,189,195
86 Avicennia germinas 7:175 Avicennia marina 7:176,180,183,184, 194,195 Avicennia officinalis 7:176,181,182, 189,195 Avicennia resinifera 7:193 Avicennia sp. 7:176 Avicennia tomentosa 7:189 Avicenol 4:372,373 Avicine 14:770;27:156 fagaronine 27:156 sanguilutine 27:156-158,161,162 terihanine 27:156 Avicularia 17:193 Avicularin 26:359 Avidin 18:919 Avidinphosphatase assay 4:284 125I-AVR9 25:400 Avrainvillea longicaulis 25:787 Awamycin 21:420,435;23:62,86 configuration of 23:86 E configuration in 23:62 Z configuration in 23:62 Axamide-1 6:5 fromAxinella cannabina 6:5 synthesis of 6:5,6 Axamide-3 21:330,366 Axane skeleton 25:848,850 Axenomycin 19:555 Axial 2-1ithiotetrahydropyrans 10:380 by reduction with lithium di-tertbutylbiphenylide 10:380 from 2-(phenylthio)tetrahydropyrans 10:380 Axial C-glycopyranosides 10:365,366, 382 Axillarin 7:26 Axillaroside 7:26 Axinella 25:847 Axinella cannabina 6:5;21:329,349,364; 25:848,852,85328:658 axamide-1 from 6:5 axisothiocyanates from 28:658 axisonitrile-1 from 6:5 axisothiocyanate 2 from 28:658 axisothiocyanate 3 from 28:658 axisothiocyanate 4 from 28:658 sesquiterpenoid from 28:658 Axinella carteri 21:254,270;25:714
Axinella sp. 21:270;25:705 Axinella verrucosa 21:270 Axinella weltneri 25:700 Axinellamine B 25:778,779 Axinellamines 25:778 Axinellida 25:847;26:464 Axinellida order 28:658 Axinyssa 25:694,847,848,859 Axinyssa aplysinoides 21:354;25:852, 853,858 Axinyssa fenestratus 25:852;26:463, 464;28:662
10-isothiocyanato-4,6-
amorphadiene from 28:662 4-isothiocyanato-9-amorphene from 28:662
10-isothiocyanato-5-amorphen-4-
ol from 28:662 Axinyssa. sp. 21:351,353,355,356,359, 364,366,367 ;28:661 Axisonitrile 26:810 Axisonitrile- 1 6:5;21:364 fromAxinella cannabina 6:5 synthesis of 6:5,6 Axisonitrile-2 21:349 Axisonitrile-3 21:330,351,356,359,365; 26:812 3-Axisothiocyanate 25:848 4-Axisothiocyanate 25:852 1-Axisothiocyanate 25:852 (+)-Axisothiocyanate-2 25:853 Axisothiocyanate-3 21:330,351,359 Axon terminals 21:7,9,16 Ayamenin A 22:473 Ayamenin B 22:473 Ayani 7:226,411-413 Ayanin 23:798 Ayapin 23:359 Ayobangira 21:595 Aza spirocycle 10:215,216 Aza-[2,3]-Wittig rearrangement 19:22, 45,50 2-Azaallyl anions 1:344-347 by deprotonation of imines 1:344-347 by C-Si of C-Sn bond cleavages 1:344-351,353 from imines 1:344-347 from N-lithioimidazolidines
87 1:344,349-351 from N-metalloaziridines 1:344,348,349 generation of 1:348,350 geometry of 1:348,350 Azaallylic anions 4:547 with aryl halides 4:547 Aza-annulation 18:315-386 of enamine related substrate 18:315-386 Aza-annulation reaction 18:373-386 asymmetric induction in 18:373-386 8-Azabicyclo [3.2.1] octan-3-one 14:573,574 asymmetric cleavage of 14:573,574 N-protected 14:573,574 9-Azabicyclo [3.3.1 ] nonan-3-one 14:571-574 trimethylsilyl enolate 14:572,573 with chiral lithium amide 14:571-574 Azabicyclo [3.3.1] nonane 11:28021-Azabicyclo [4.3.0] nonane (octahydroindolizine) 11:229 Azabicyclo ketone system 14:571-574 asymmetric cleavage of 14:571-574 cis-c~,c~'-disubstituted piperdine by 14:571-574 pyrrolidines by 14:571-574 Azabicyclo[2.2.1] heptane 19:667endo-7-Azabicyclo[2.2.1 ] heptanol 19:71 Azabicyclo[2.2.1] heptanone 19:71 3-Azacephalosporine 12:137 Aza-Claisen rearrangement 16:467 Aza-Cope reaction 16:481 Aza-Cope rearrangement 1:68,69 Mannich directed 1:68,69 Aza-Cope-Mannich strategy 16:435 Aza-Diels-Alder approaches 16:456 Azadiene Diels-Alder 3:311 1-Azadiene Diels-Alder cycloadditions 16:457 2-Azadienes 4:7,10-14,17 metalloenamines from 4:7, 10-14,17
Azadirachta indica 9:293-311;13:644; 15:384 ;22:95 ;26:466,814 ;28:388, 395,389,401,404,414,573,581 azadirachtin from 26:466 Azadirachta indica oil 28:388,395 against bee mites 28:387 against blood sucking ticks 28:395 Azadirachtin 7:397;9:93,94,96, 103-105,297 ;23:488 ;30:696 Azadirachtol 9:308 Azadirol 9:297,298,300,306,308 Azadirone 9:302,304-306 Azafluoranthenes 1:167,169 Azafria 30:528,529 structure of 30:529 Azafulvene 9:596 Azafulvene bilane 9:593,595 Azahexatriene 3:395 thermal cyclization of 3:39522-Azahexatriene 3:395 thermal cyclization of 3:395 Azalides 13:161,162 Azaphilones 23:343;26:450 6-Azaspiro (4,5) decane 25:871 Azasteroids 4:540 Azasugars 14:179 Azatidine acetates 23:195 isomerization of 23:195 Aza-Wittig reaction 1:168,169 Azepine ester 19:99 Azepine-type bromopyrrole 25:799 3-Azetidinol 18:677 from Chara globularis 18:677 Azetidinone 13:87;4:437,441,448,450, 452-454,457,458,461-466;8:264 1-Azetidinone acetic acid 12:138 Azetidione derivatives 13:500 Mori's synthesis of 13:500 Azetidone 5:412-414 Azidation reaction 19:311 asymmetric 19:311 Azides 3:49 dipolar cycloaddition 3:49 thermolytic cyclization of 6:429 1-Azido- 1,2,3-trideoxy-D-arabino-oct-4ulose 12:350 8-Azido- 1-p-menthene 11:288 reduction of 11:288
88
6-Azido- 2,4-di-O-benzyl-3,6-di-deoxyot-D-ribo-hexopyranosyl chloride 14:145 2-Azido-2-deoxy derivative 6:388 of D-glucose 6:388 ofmuramic acid 6:387,388, 402,403 2-Azido-2-deoxy-D-glucose derivative 6:388 3-Azido-3-deoxy- 1,2-O-isopropylidene~x-D-glucofuranose 12:325 Azido-4-deoxy-D-mannose 12:316 5-Azido-5-deacetamido-Neu 30:426 6-Azido-6-deoxy-D-arabino hexulose 10:536 Azido-6-deoxy-L-xylo-hexulose 10:536 1-Azido-abscisic acid 27:330,331 2-Azidobenzaldehyde 13:448 Azidobutenolides 13:448 a-Azidocinnamates 1:165 2-Azido-D-arabino-hexofuranoses 6:369 5-deoxy-5-(phenylphosphinyl) Lfucosamine from 6:369 from D-ribo-hexafuronose 6:363 Azidodeoxy-myo-inositol 18:411 Azido-ene reaction 16:473 Azidonitration 1:420,421 ;10:465 Azido-olefin cyclization 13:447,448 4-Azidosampangine 23:6 Azidothymizine 23:97 Aziridine 10:138,139 from (S)-phenylglycinol 10:138,139 azomethine ylides from 1:328-331 fused 1:189,197 nucleophilic opening 1:201,202 photochemical opening 1:328 synthesis of 1:189,197 thermal opening in 1:328 Azithromycin 13:161,162,183 Azobisisobutyronitrile (AIBN) 10:204, 208;21:746;24:16-18 Azocasein method 30:841 for proteolytic activity 30:841 Azocine 8:210 synthesis of 8:210
Azodicarbonyldipiperidine 19:225 Azodicarboxylate 22:198 Z-Azoene 23:459 Azohydroperoxide 9:580otAzoles 22:58 Azomethine ylide cycloadditions 1:329, 330 by aziridine thermolysis 1:329, 330 intramolecular 1:329,330 Azomethine ylides 1:331-332 by 1,2-H shifts 1:331-332 formation of 1:324-344 generation of 1:324,339 preparation by aziridine opening 1:328-331 preparation by desilylation 1:324-328 preparation from c~-amino acids 1:331-338 Azomonas macrocytogenes 19:814 4-Azoniaspiro [3,3] heptane-2,6 diol 18:677 from Chara globularis 18:677 Azospirillum lipoferum 4:197 Azotobacter vinelandii 26:1151,1152, 1211 Azotobactins 19:812 Azoverdin 19:0" 1 Azukisapogenoi B 25:97 Azukisaponin 25:95 Azukisaponin II 25:95,104,105,115, 116,118,203,226 Azukisaponin V 25:104,115,116,118, 120,203,226 Azukisaponin VI 25:97,104 Azulen 26:305 Azulene quinones 14:314 Azulenes 14:332 autooxidation of 14:332 electrochemical oxidation of 14:325 oxidation of 14:332-334 prostaglandins 16:367 Bsynthesis of 16:367
89 B/C-trans-morphinan 12:464-471 diastereoselective synthesis of 12:464-471 B4-2313 A, B 21:411,412 B-90063 25:842 Baadische Anilin 28:71 vitamin A synthesis by 28:71 Babesia bigemina 28:398 Babesia bovis 28:398 Babesia sp. 26:694,835;28:398 BABS 21:752-754 BABS-M-receptor complex 21:754 Babylonia japonica 11:724 Baccatin I 11:4,9;12:179 Baccatin III 11:3,4,179,180;12:179, 180;20:81 ;22:218;23:490,491 ;25:245 Baccharin 30:735 structure of 30:735 Baccharinoids 30:743 Baccharinol 30:736 structure of 30:736 Bacchariolide A 30:716 structure of 30:716 Bacchariolide B 30:717 structure of 30:717 Baccharis anomala D.C. 30:750 microsomal activation by 30:750 Baccharis articulata 15:22;30:706,708, 723,743,744,750 articulin from 30:708 as antidiabetic 30:706 as decoctions 30:706 as infusions 30:706 bacchotricuneatin A from 30:708 barticulidiol from 30:708 [3-caryophyllene from 30:723 in treatment of rheumatism 30:744 in ulcers 30:744 inhibition of viral infectivity by 30:743 neo-clerodane type 30:708 nerolidol from 30:723 use as raw material for preparation of phytotherapeutic drugs 30:750 Baccharis boliviensis 30:711,712,730, 742
coumaric acids 30:730 ent-clerodane derivatives from 30:711 ent-clerodane furanoditerpenoid from 30:711 labdane-type diterpenes from 30:712 trypanocidal effect of 30:742 Baccharis calliprinos Grised 30:746 Baccharis calvescens D.C. 30:731 p-hydroxyacetophenones from 30:731 Baccharis cassinaefolia 30:708 bacchotricuneatin A from 30:708 Baccharis conferta 30.704,740,748 against Escherichia coli 30:740 antibacterial activity against Micrococcus luteus 30:740 as laxative 30:705 for stimulating urination 30:705 in treatment of baldness 30:705 in treatment of gastrointestinal illnesses 30:748 in treatment of insect bites 30:705 in treatment of stomach aches 30:704 triterpenoid oleanoic acid methyl ester from 30:740 Baccharis cordifolia 22:348;30:705, 717,719,733,743,745,751 as anti-inflammatory 30:705 baccharinoids from 30:717 extract of 30:733 in toxic disease 30:751 in treatment of horse's external parasites 30:705 macrocyclic trichothecenes from 30:743 roridins from 30:717,751 schottenol glucoside from 30:719 to treat horse's distemper 30:705 toxins from 30:751 ursolic acid from 30:719 uvaol from 30:719 verrucarins from 30:717 Baccharis cordobensis 30:722 cadinol from 30:722
90 cubenol from 30:722 essential oil from 30:722 nerolidol from 30:722 Baccharis crispa 30:722,723,739,743, 744,745,750 antibacterial activity against 30:739 antifungal activity against 30:739 essential oil from 30:722 in treatment of liver diseases 30:744 nerolidol from 30:722 as phytotherapeutic drugs 30:750 Baccharis dracunculifolia 30:723,730 dracunculifosides A-J from 30:730 Baccharis floribunda 30:706 Baccharis gaudichaudiana 25:251,269; 27:14,24,25 ;30:706,734 as antidiabetic material 30:706 arabinoside gaudichaudioside A from 15:21 as decoction 30:706 as infusion 30:706 gaudichandioside A from 27" 14, 24,25 in P-388 lymphocytic leukemia cells 30:734 Baccharis genistelloides 25:941; 30:706,711,720,733,739,740,743, 744,746,748-750 against HSV-1/VSV 30:743 against Staphylococcus aureus 30:739 anti-inflammatory constituents from 30:746 against Candida albicans 30:739 against gram-positive bacteria 30:739 antimicrobial activity of 30:740 antimutagen constituents from 30:733 apigenin from 30:733 as anti-inflammatory material 30:750 as antithermic 30:706 cirsimaritin from 30:733 diterpene lactone from 30:740
effects on bile duct 30:750 effects on bone marrow 30:750 effects on cardiac function 30:750 effects on liver 30:750 effects on pancreas 30:750 effects on serum lipids 30:750 genkwanin from 30:733 hispidulin from 30:733 m anaemia 30:706 m diabetes 30:706 m diarrhoea 30:706 m digestive disorders 30:706 m indigestion 30:706 m inflammation 30:706 m intestinal worms 30:706 in leprosy 30:706 an liver disorders 30:706,733,749 in malaria 30:706 in rheumatism 30:733 m sore throat 30:706 m tonisilitis 30:706 in ulcers 30:706 m urinary disorder 30:706 [3-sitosterol from 30:720 stigmasterol from 30:720 structure-activity relationship of 30:733 use in liver diseases 30:749 use in wounds 30:744 Baccharis genus 30:707,733,738 antibacterial activity of 30:738 antifungal activity of 30:738 constituents of 30:707,733 diterpenoids from 30:733 epi-methyltrineracetal from 30:707 flavonoids from 30:733 methyltrineracetal from 30:707 neo-clerodane type diterpene 30:707 secondary metabolites from 30:738 Baccharis glutinosa 30:704,739 antimicrobial activity of 30:739 as contraceptive 30:704 for digestive disorders 30:704 for gynecological disorders 30:704
91
for skin diseases 30:704 in treatment of infectious diseases 30:739 in weight reduction 30:704 to clean wounds 30:704 to treat scalp diseases 30:704 Baccharis grisebachii 30:705,730,733, 739,745 coumaric acids from 30:730 3-(3,3-dimethylallyl)-p-coumaric acid from 30:730 extract of 30:733 for decoctions 30:705 for poultices 30:705 for wound healing 30:705 inhibitory activity of 30:745 spectrum of action of 30:739 Baccharis halimifolia L. 30:718 baccharis oxide from 30:718 Baccharis heterophylla 30:718 oleanolic acid from 30:718 Baccharis incarum 22:352;30:709,744 bincatriol from 30:709 3'-methoxycalicopterin 7'methyl-sudachitin from 22:352 neo-clerodane diterpenoid from 30:709 Baccharis intermixta Gardn. 30:713 Baccharis L. 30:704 biological activities of 30:704 traditional uses of 30:704 Baccharis latifolia 30:721,731 oil from 30:721 p-hydroxyacetophenones from 30:731 Baccharis macraei 30:710 clerodane derivatives of 30:710 hardwickiic acid from 30:710 hautriwaic acid from 30:710 Baccharis magellamica (Lam.) 30:731 Baccharis medullosa 30:712,744 as anti-inflammatory material 30:744 Baccharis megapotamica 30:717,736, 751 activity against P-388 leukemia 30:736 against human carcinoma 30:736 as cytotoxic agents 30:717
baccharin from 30:736 baccharinoids from 30:717 baccharinol from 30:736 bioassay-guided fractionation of 30:736 extract of 30:736 isobaccharin from 30:736 isobaccharinol from 30:736 roridins from 30:717 toxins from 30:751 verrucarins from 30:717 Baccharis multiflora 30:705,713 against catarrhs 30:705 as infusion 30:705 ent-kaurenic acid from 30:713 ent-kaurenol from 30:713 for urinary problems 30:705 kaurane-type diterpenoids from 30:713 Baccharis myriocephala D.C. 750 Baccharis myrsinites 30:709,718,729 clerodane diterpenoid from 30:709 coumaric acid from 30:729 maniladiol from 30:718 oleanolic acid from 30:718 structure elucidation of 30:709 Baccharis myrtilloides 30:723 germacrane D from 30:723 Baccharis notosergilla 30.705,739,740, 742,743 against gram-positive organisms 30:740 against Trypanosoma cruzi 30:742 antibacterial activity of 30:739, 740 antifungal activity of 30:739 as digestive agent 30:705 as diuretic 30:705 essential oil of 30:740 in folk medicine 30:705 Baccharis oxide 30:717 baccharis oxide from 30:706 structure of 30:717 Baccharis oxydonta 30:711,728 ent-labdane diterpenes from 30:711
92 pinobanksin from 30:728 pinocembrin from 30:728 Baccharis paniculata 30:710,712,731, 740 acetylenic lactones from 30:731 against phytopathogenic fungi 30:740 for antifungal activity against human pathogens 30:740 3-methyl ether flavone 30:740 neo-clerodane diterpenoids from 30:710 prenylated coumarin from 30:740 Baccharis pedunelata 25:251 Baccharis petiolata 25:251 Baccharis pingraea 30:712 furolabdane diterpenoids from 30:712 furolabda-6,8-dien- 17-oic acid 30:from 30:712 furolabda-7-en-17-oic acid from 30:712 Baccharis pteroniodes 30:711 ent-clerodane diterpenoids from 30:711 neo-clerodane diterpenoids from 30:711 Baccharis ramoisissima 30:713 ent-kaurenic acid from 30:713 ent-kaurenol from 30:713 Baccharis rhetinoides 30:746 anti-inflammatory flavonoids from 30:746 homoeriodictyol from 30:746 Baccharis rubricaulis 30:706 for treating mucous ailments 30:706 Baccharis rufescens 30:723,744 as anti-inflammatory agent 30:744 limonene from 30:723 nerolidol from 30:723 Baccharis salicifolia 30:705,707,718, 72i,722,731,732 t,accharis oxide from 30:718 e ~t-clerodane derivatives from 30:707 essential oil from 30:722
for diarrhoea 30:705 for dysentery 30:705 for inflammation 30:705 germacrane D from 30:722 oils from 30:721 prenyl derivatives from 30:731 Baccharis salicina 30:715 bacchariolides from 30:715 chemical analysis of 30:715 guaianolides from 30:715 Baccharis santelicis 30:709 Baccharis sarothroides 30:705,710,733 centaureidin from 30:733 cytotoxic flavonols from 30:733 3,4'-dimethoxy-3',5,7trihydroxyflavone from 30:733 hautriwaic acid from 30:710 2[3-hydroxyhautriwaic acid from 30:710 identification of 30:733 inhibitory activity against human carcinoma 30:733 Baccharis scoparia 25:251;30:711,712 labdane aldehyde from 30:712 Baccharis serraefolia 30:705,720,739, 748 against Candida albicans 30:739 against Staphylococcus aureus 30:739 against gram-positive organisms 30:739 mechanism of action of 30:748 phytol from 30:720 [~-sitosterol from 30:720 spasmolytic action of 30:748 to treat diarrhoea 30:705 use in gastrointestinal illnesses 30:705 Baccharis species 29:580;30:706,707, 711,737,740,741,750, antineoplastic activity of 30:737 apigenin from 30:740 assay-guided fractionation of 30:737 for preparation of phytotherapeutic drugs 30:750 genkwanin from 30:740 pentacyclic triterpenoids from 30:737
93 toxicological evaluation of 30:750 Baccharis spartioides 30:715,723 essential oil of 30:723 spartidienedione from 30:715 Baccharis sphaerocephala 30:715 amorphane sesquiterpene y-lactol from 30:715 O-methylbaccharocephol from 30:715 Baccharis sternbergiana 30:712 Baccharis timera 7:427 Baccharis tola 30:714,725 ent-4c~-hydroxy- 19-norbeyer- 15ene from 30:714 ent-beyer- 15-en- 17,19-ol from 30:714 ent-beyerane-type diterpenoids from 30:714 flavone from 30:725 Baccharis tricuneata 30:706,708,719 c~-amyrin acetate from 30:719 bacchotricuneatin A from 30:708 for diabetes 30:706 for skin infections 30:706 friedelin from 30:719 13-sitosterol from 30:719 ursolic acid from 30:719 Baccharis trimera 30:706 as antithermic agent 30:706 for digestive disorders 30:706 for liver disorders 30:706 use in anaemia 30:706 use m diabetes 30:706 use m diarrhoea 30:706 use m indigestion 30:706 use m inflammation 30:706 use m intestinal worms 30:706 use in leprosy 30:706 use m malaria 30:706 use m sore throat 30:706 use m tonsilitis 30:706 use in ulcers 30:706 use m urinary diseases 30:706 Baccharis trinervis 30:705,725,743 against human immunodeficiency virus 30:743 antiviral activity of 30:743
apigenin from 30:725 flavones from 30:725 flavonol from 30:725 for gastrointestinal disorders 30:705 in dizziness 30:705 in MT-2 infected cells 30:743 in treatment of edema 30:705 in treatment of high fever 30:705 in treatment of muscle cramps 30:705 in treatment of sores 30:705 in treatment of typhoid fever 30:705 inhibition of HSV-1 30:743 pectolinaringenin (5,7dihydroxy- 6,4'-dimethoxyflavone) from 30:725 pe dunletin (5,4 '-dihydro x y- 3,6,7trimethoxyflavone) from 30:725 salvigenin (5-hydroxy-6,7,4 'trimethoxyflavone) from 30:725 Baccharis triptera Mart 30:749 in gastrointestinal disorders 30:749 in gastrointestinal hyperactivity 30:749 Baccharis tucumanensis 30:705,733, 744 anti-inflammatory action of 30:745 as abortive agent 30:705 extract of 30:733 in carrageenan foot edema test 30:745 role in croton oil induced mouse ear edema test 30:745 Baccharis uncinella D.C. 30:723 essential oil from 30:723 Baccharis vaccinoides 30:705,710,739 against Candida albicans 30:739 against Staphylococcus aureus 30:739 antimicrobial activity in vitro 30:739 for gastrointestinal disorders 30:705
94 hautriwaic acid from 30:710 2[3-hydroxyhautriwaic acid from 30:710 Baccharis varians 30:728,729 3-acetoxyflavanones from 30:728 Bacchotricuneatin A 30:709 structure of 30:709 Bacillarophyceae 6:13 Bacillus acidcaldarius 23:92 Bacillus antharacis 12:400 Bacillus aurantinus 5:601 Bacillus calmette-Guerin (BCG) 25:462,497 Bacillus cereus 7:413;22:273,274; 23:344,473 ;25:259;26:1091 Bacillus ganera 29:311 Bacillus macerans 27:8,365 Bacillus marinus 23:258 Bacillus megaterium 10:585;12:104; 23:76;27:365 Bacillus pumilis 7:70,308,390;30:693 Bacillus sp. 12:103;21:391,599;25:155 Bacillus stearothermophilus 29:266 Bacillus subtilis 5:302,304,368,418, 308,353;8:353;10:117,104,400,345, 692,290,556,559;18:778;21:237,262, 266,267,284,610;22:627,628;23:41, 344,473 ;24:713;25:220,258-260,765, 770,776-779,782,789,792,863 ;26:79, 333,334,1093 ;28:223,693 ;29:272; 30:629,693,738 antifungal activity against 30:738 caffeic acid inhibition by 30:225 effects of phenols on 28:223 of drummondins A-C 30:629 of phloroglucinols 30:629 role of 30:225 Bacillus thiaminolyticus 15:390 baciphelacin from 15:390 Bacillus thuringiensis vat. kurstaki 28:404 Baciphelacin 15:388,390,409,410 Bacitracin 9:413 ;26:366,374 Backbone rearrangements 7:159, 161-166 Bacogenin A1 23:503,511 transformation of 23:503,511
Bacogenin A3 23:503 Baconipyrones A-D 17:25 Bacopa monnieri L. 22:513 for epilepsy 22:513 Bacopa monnira L. 22:513;23:489,499 for epilepsy 22:513 Bacopasaponin A 23:503,504 13C-NMR chemical shifts of 23:509 ~H-NMR chemical shifts of 23:504 Bacopasaponin B 23:503 ~3C-NMR chemical shifts of 23:509 ~H-NMR chemical shifts of 23:506 Bacopasaponin C 23:503,507 13C-NMR chemical shifts of 23:510 IH-NMR chemical shifts 23:507 Bacopasaponin D 23:503,510 13C-NMR chemical shifts of 23:510 Bacteria 9:537-557 siderophores from 9:537-557 Bacterial cell wall 6:385,395,397,406 Bacterial effects 30:152 of Streptococcus mutans 30:152 Bacterial growth inhibitors 17:101 Bacterial hydrolysis 30:305 of sugar 30:305 Bacterial infections 30:408 Bacterial origin 28:434 acaricidal agents of 28:434 Bacterial polysaccharides 4:195 L-glycero-D-mannoheptose in 4:195 Bacterial reverse mutation test 27:303 Bactericidal effect 26:1095 of HMTP on Sacchomyces epidermidis 26:1095 Bactericidal properties 21:225 Bactericidal/permeability-increasing protein 27:807 Bactericides 28:390 used of essential oil 28:415,390 Bacteriorhodopsin 4:526,720,823 (2S,2'S)-Bacterioruberin 30:517 structure of 30:517
95
Bacterioruberin 7:355-357;20:599; 30:523 as cell membrane stabilisers 30:523 Bacterium pseudomonas 9:322 Bacteroides fragilis 14:107 (-)-Bactobolin 16:22 Bactobolin 16:3 antibacterial activity of 16:3 antitumor antibiotic 16:3 from Pseudomonas yoshitomiensis Y-12278 16:3 total synthesis of 16:3-26 Bademi 23:659 Baekhousia citriodora 25:132 Baeyer-Meerwein rearrangement 24:30-32 Baeyer-Villiger oxidation 21:301,417; 24:30-32,42,43,191,192 Baeyer-Villiger reaction 27:94 9-hydroperoxy- 10,12,15octadecatrienoic acid by 27:74 Baeyer-Villiger rearrangement 4:139, 153,647,667;8:154,597,598;27:74 Baeyer-Villiger ring expansion 13:601 Bafilodides 26:495 Bafilomycin A1 26:453 Bafilomycin B2 26:453 Bafilomycin C1 26:453 Bahiensol 29:253 antimicrobial activity of 29:253 Baicalein 22:509;25:593,595;27:435; 29:572,581,584 ;30:55,69-72,288 anti-inflammatory actions of 30:72 as anti-allergic 30:71,72 biological activity of 27:435 effects on HIV- 1 protease 29:572,581 effects on LELA 29:584 effects on MMP 29:581 inhibitory action of 30:70 Baikal 23:656 Baiyumine A 13:348,349 from Citrus grandis 13:348,349 Baiyumine B 13:350 from Citrus grandis 13:350
(+)-Baiyunol 1:666-669 synthesis of 1:666-669 thermal glycosidation of 8:362 Baiyunoside 27:14,25 structure of 27:15 Baiyunoside 1:666-670 synthesis of 1:666-670 from Phlomis betonicoides 15:20 Bai-yun-shen 1:666 baiyuoside from 1:666 Bakankoside 6:503 from Strychnos vacacoua 6:503 Bakankosine 26:101,102 chemical transformation of 26:101,102 Baker's methodology 21:442 Baker's conditions 12:46,47 Baker's yeast 4:158,263,324,325,340, 341,410,542,543,552,553 ;6:13; 10:410;13:58,59,307,309;20:573, 593,818,820;25:143,145 Baker's yeast reduction 13:662,176 Balaenonol 5:744,747-749,149,150,152 Balam 23:652 Balanitaceae 7:426,427 Balanites aegyptiaca 7:426 Balanocarpol 26:556,561 Balanocarpus zeylanicus 23:547 Balanol (44) 27:868,869 Balanophonin 20:642 from Balanophora japonica 20:642 Balanophora elongata 29:583,586 Balanophorajaponica 1:666 balanophonin from 20:642 Balanus amphirib 25:783,784,785 Balanus amphitrite 21:366 BALB/3T3 12:400 staurosporine activity against 12:400 BALB/c mice 28:534;30:592 epidermal cell culture of 30:592 Meth A sarcoma in 28:534 Balchanolide 7:230 Baldrinal 7:458,459 Baldwin's rule 14:792,793 Baleabuxidine 2:205 Baleabuxoxazine-C 2:205
96
Ballota nigra 30:268 flavonoids from 30:268 Balsamiton 27:591 Balsamodendron mukul 5:695 Balsamodendron sp. 22:513 for epilepsy 22:513 Baluchistamine B 20:270 Bamboo shoots 6:187 GA19 from 6:187 Bamicetin 4:241,243-245 Ban condensation 1:135 Banerjee 29:174 pisiferic acid synthesis by 29:174 Banerjee and Az6car 29:208 triptolide synthesis by 29:208 Banerjee et al. 29:194,215 Carnosic acid synthesis by 29:194 miltirone synthesis by 29:215 Banksia grandis 19:246 Bannucine 5:167-169;9:185,186 Banwell 29:377,378 allocolchicinoids total synthesis by 29:377,378 Baogongteng A 21:751,752 synthesis of 21:751,752 Baogongteng C 21:751 B AP (6-benzylaminopurine) as cytokinin 7:90,94 Baphia nitida 21:616 Baptisiasaponin 25:95 Barbamide 25:757,785,786,889,890 Barbatol 25:250 Barbatosides B 26:56 analgesic activity of 26:56 as anti-inflammatory agent 26:32 Barbatosides A 26:56 analgesic activity of 26:56 as anti-inflammatory agent 26:32 Barbilophzia hatcheri 5:730 Barbilophzia lycopodioides 5:730 Barbiturates 25:528 Barceloneic acids 24:450 as human FPTase inhibitors 24:450 structures of 24:450 Barley 28:260 syringic acid in 28:260 vanillic acid in 28:260
Barley endosperm assay 6:181 Barnacle settlement inhibitors 17:103 Barosma betuling 27:375 Barosma crenulata 27:375 Barrett's approaches 12:9-11 for oxahydrindene subunit 12:9-11 ofavermectins 12:9-11 Barrigenic acid 7:132 from Barringtonia acutangula 7:132 R1-Barrigenol 21,22-di-O-angelate 7:139,141 Barrigenol A1 21:673 Barringtogenic acid 7:132 from Barringtonia racemosa 7:132 Barringtonia acutangula 7:132 barrigenic acid from 7:132 barringtonic acid from 7:132 barrinic acid from 7:132 tangulic acid from 7:132 Barringtonia racemosa 7:132;22:514 barringtogenic acid from 7:132 for epilepsy 22:514 Barringtonia sp. 7:132,133 triterpenes of 7:132,133 Barringtonia speciosa 7:132 anhydrobartogenic acid from 7:132 bartogenic acid from 7:132 19-epi-bartogenic acid from 7:132 Barringtonic acid 7:132 from Barringtonia acutangula 7:132 Barrollier reagent 19:755 Barticulidiol 30:709 structure of 30:709 Bartlett demethylation 8:119 Bartlett method 25:435 Bartlett pear ester 10:152 Bartogenic acid 7:132 from Barringtonia speciosa 7:132 19-epi-Bartogenic acid 7:132 from Barrintgonia speciosa 7:132
97 Barton oxidation 13:72 9-BBN (9-borabicyclo-[3.3.1 ] nonane) 13:72 Barton radical decarboxylation 18:75, 340 Barton reaction 14:160 Barton reduction 12:303 Barton's modification 19:135 Barton-Crich's decarboxylative oxygenation 24:43,44 Barton's procedure 6:282-288,607 Barton's protocol 6:21 in free radical deoxygenation 6:21 Barton's reaction 6:228,230,231 Barton-type deoxygenation 20:71 Base promoted cyclisations 4:541 of aryl halides 4:541 Base-catalysis 16:220 Base-catalyzed equilibration 14:460 Base-induced rearrangement 12:91 mechanism of 14:372-374 of hydroazulene mesylates 14:22-25 of hydronaphthalene- 1,4-diol monosulfonate esters 14:356 of hydronaphthalene tosylates 14:368-370 Basidiomycetes 9:220,317;21:187;
18:813,814;25:129,150
fruiting body formation 1:680 glycosphingolipids of 18:813,814 Basidiomycetous fungus 30:403 in folk medicine 30:403 mode of antiviral activity of 30:403 Basidiomycota 22:246 Basidiomycotina 9:202;23:109 Basilicum polystachyon 22:514 for epilepsy 22:519 Basilicum polystachyon 22:514 for sedative in convulsions and epilepsy 22:514 Bastadin 10:630,632,633-638;25:719, 720 Bastadin-6 10:630,636-638 Bastaxanthin 6:150;10:153
Bastaxanthin B 28:714 as novel carotenoid sulfate 28:714 Bastaxanthin C 28:714;30:526,527 as novel carotenoid sulfate 28:714 structure of 30:526,527 Bastaxanthin D 28:714 as novel carotenoid sulfate 28:714 Bastaxanthin E 28:714 as novel carotenoid sulfate 28:714 Bastaxanthin F 28:714 as novel carotenoid sulfate 28:714 Bastaxanthins 30:526 Bastaxanthins C,B,D,E,F 9-BBN 6:20 reaction with 13-furanone 6:20 Batasin 23:348 Batasin I 23:342 Batrachotoxinin 11:244;21:73 Batramiaflavone 20:283 Batzella sp. 25:708,760,774,790,822, 852;27:881 ;28:715 Batzella sponge 28:685 against Candida albicans 28:686 antifungal activity of 28:686 Batzelladine A 25:709 Batzelladines 25:708 Batzelline A 25:822 Batzelline B 25:822 Batzellines 25:707 Batzellines-isobatzellines 25:822 Baudoin-Gu6ritte 29:407 rhazinilam synthesis by 29:407 Bauhinia bauhinioides 29:603 Bauhinia microstachya 29:573 Bauhinia mollis 29:603 Bauhinia pentandra 29:603 Bauhinia variegata 29:603 Bavachalcone 28:228 biological activity of 28:228 Bayberry 13:660 Bayer-Villager oxidation 25:425 24-epi-catasterone by 25:425 Bayogenin 7:432 molluscicidal activity of 7:432 Bayogenin bidesmosides 21:634
98 Bazzanene 9:212,213,308,309,520,521 Bazzanenone 10:308,309 Bazzania 21:281 BBE (berberine bridge enzyme) 11:204 BBN 4:116,117 reduction with 4:116,117 trans-BC-ring fusion 12:205 stereochemistry of 12:205 BCA method 25:433 BCAs 21:182,191,193,202,203,218, 224,226,229,240 B-cell leukaemia 21:137 BCG/LPS induced hepatotoxicity 25:471 BE-13793C 12:366,370,396 antitumor activity of 12:396 topoisomerase I and II inhibitors of 12:370 Beaucage sulfurizating agent 13:269 Beauvaria bassiana 23:20,21,34; 28:397,404 Beckman fragmentation 19:486 of anti-oxime 19:486 of erythromycin-9-oxime 13:160,161 of oxacyclopentanone ring 16:221 of oxime 16:240,330;19:14,498 Bee parasites 28:387 formic acid in 28:387 Beer's law 15:423 Beesia 25:180 Beet armyworm 12:397 Beewax 19:246 Begonia plebeha 19:764 Behavioral dysfunction 30:368 effect of serotonergic neurotransmission on 30:368 Behilic acids 22:612 Beta-eudesmol 24:883-887 p-phenylene-polymlethylene bisammonium derivatives 24:883-887 Belemnitella sp. 13:330 Belladonna 22:422 Bellis perennis 21:662 Bellus rearrangement 8:205 Bemangovitra 26:1037,1038 Benanomicin A 22:62
Benanomicin B 22:62 Bencimidazol 25:669 Bengamide A&B 26:485 Bengazole A 26:488 Benincasa cerifera Savi 22:514 for epilepsy 22:514 Benincasa hispida 22:513 use for epilepsy and hysteroepilepsy 22:513 Benthiozepines 25:534 diltiazem 25:534 Benz [a] anthracene antibiotics 11:134 antibacterial activity of 11:134 antitumor activity of 11:134 Benzal malonates 9:224-227 inhibitory activity of 9:224-227 synthesis of 9:224-227 Benzaldehyde 28:406 acaricidal properties of 28:406 Benzaldehyde acetal 14:477 chromium tricarbonyl complex 14:477 from (2R,3R)-2,3-butanediol 14:477 with trimethyl aluminum and titanium tetrachloride 14:477 Benzamido-2-deoxy-[3-D-glucopyranosyl)7-2-theophylline 4:238 Benz-annulation reaction 1:505,506 Benzatropine 22:732 3-Benzazepine derivative 6:474,484 Benzazepines 1:169;25:534 3-Benzazocine 6:469,471 synthesis of 6:469 2-Benzazocine N-oxide derivative 6:472 Benzazocines 1:192,193 ;6:468-471,442 3-Benzazonine derivative 6:475,476 Benzene ring 27:355 steric effect of 27:355 Benzene thiol 11:358 1,2-Benzenedithiol 11:357 1,2,4,5-Benzenetetracarboxylate 11:124 Benzidine 7:457 Benzilic-type rearrangement 3:226 Benzimidazole antidote 22:464 Benzimidazoles 12:3 Benzo [a] pyrene 7:8 carcinogenicity of 7:8
99 Benzo [a] pyrene oxides 7:8 absolute configuration of 7:8 from benzo [a] pyrene 7:8 Benzo [a] pyrene-(-)-7R,8R-dihydrodiol 7:8,9 Benzo [a] pyrene-7R,8S-dihydrodiol9S, lOR-epoxide 7:8,9 8,13-Benzo [a]naphthacene quinone 11:123 from naphthacene glutarate 11:123 Benzo [c] phenanthridine alkaloids 14:769-803 biomimetic synthesis of 14:769-803 biosynthesis of 14:771-773 from protoberberines 14:769-803 oxygenative conversion of 14:779-784 Benzo[c]naphta [1,2-E] azonine derivative 6:481 Benzo [c]phenanthridine alkaloids (QBA) 1:187,542;27:819 biological activities of 27:178 chemistry of 27:155 Benzo[c]phenanthridines 5:42 Benzoacetonitriles 25:719 Benzochromones 18:978 Benzocyclobutanol 14:685 Benzocyclobutanone 14:685 synthesis of 14:685 via (2 +2) cycloaddition 14:685 Benzocyclobutenes 3:434-437 Benzodiazapines 21:101 ;22:508,666; 25:528;27:803 Benzodiazepine receptors 22:26 Benzodioxan 8:399,401 1,6,5-Benzodioxazonine 6:472 from 1,5-benzoxazocine N-oxide 6:472 Benzofuran 20:282;29:763 2-(p-hydroxybenzyl)-6-methoxybenzofuran as 29:767 structure of 29:767 Benzofuran lignans 26:253 Benzofuran neolignans 26:202 Benzofuran-2-carboxylic acids 30:221 Benzofuranoid terphenyls 29:279 2,3 ', 8-tri- O- acetylc yc lovariegatin
as 29:283 3 '-demetho xy-6 '-de smethyl- 5 'methoxycandidusin B as 29:282 antifeedant activity of 29:282 as 5-LOX inhibitor 29:280 as antioxidative component 29:281 benzofuranoid arenarin A as 29:282 benzofuranoid ganbajunin B as 29:280 candidusins as 29:281 cycloleucomelone as 29:279,283 cycloleucomelone leucoperacetate as 29:279 cycloleucomelone leuco-tetraacetates as 29:279 cycloleucomelone leucotriacetate as 29:279 desmethylcandidusin B as 29:282 effect on DNA, RNA, protein synthesis 29:281 in antibacterial assay 29:281 rotoleucomelone as 29:279 Benzoic acid 23:744,77125:655,660, 928,929 derivatives of 23:744,771 Benzoic acid-2 hydroxylase 25:660,669 Benzoirithiepin 25:834,835 Benzomorphans 6:471 2,6-bridge 3-benzazocine in 6:471 Benzopentathiepin lissoclinotoxin B 25:833 Benzophenanthridine alkaloids 21:108 Benzophenanthridine skeleton 21:69 Benzophenone 27:331 4H-1-Benzopyran-4-one ring system 21:123 Benzopyranopyrrole chromphore 25:776 1,2-Benzopyrone 23:337 Benzoquinone derivatives 7:183,184 1,4-Benzoquinones 16:547-570 enantiospecifir reactions of 16:547-570
100
stereospecific reactions of 16:547-570 Benzoquinones 5:774-778;20:273; 23:341 Benzosampangine 23:3,5,42 biotransformation of 23:3,5,42 Benzosampangine-[3-glucopyranoside (BZSAMM1) 23:25 Benzothiadiazole 26:846 Benzotrithiane 25:833 Benzotrithiepin S-oxides 25:834 B enzotrithiepin- 5-(methylthio) varacin 25:834 2H-3,6-Benzoxazecine derivatives 6:486 1H-2,6-Benzoxazecine derivatives 6:486 2,3-Benzoxazepine derivative 6:468 from cis-(+)-laudanosine N-oxide 6:468 Benzoxazinoid acetal glucosides 27:191-194 chemical synthesis of 27:196,207-210 enzymatic degradation of 27:191-196 Benzoxazinoids 23:342;27:211 biological activity of 27:211 Benzoxazinone acetal glucosides 27:187-190 Blepharin 27:188 DHBOA-Glc 27:188 DIBOA-Glc 27:188 DIMEBOA-Glc 27:188 DIMBOA-Glc 27:188 GDHBOA 27:188 GDIMBOA 27:188 GHBOA 27:188 GHDMBOA 27:188 GHMEBOA 27:188 GHMBOA 27:188 GIMEBOA 27:188 HBOA-Glc 27:188 HDMBOA-Glc 27:188 HM2BOA-Glc 27:188 HMBOA-GIc 27:188 occurrence of 27:187-190 Benzoxazinone acetal glucosides 27:224,225
biological role of 27:224,225 Benzoxazinones 27:185-225 biological activity of 27:185-225 biological role of 27:224 defoxification of 27:218-222 effects on animal organisms 27:212-214 synthetic access to 27:185-225 Benzoxazione aglucones 27:190-191, 195,196-207 as equilibrium of enantiomeric cyclohemiacetals 27:194 blepharigenin 27:191 chemical synthesis of 27:196-205 chemical synthesis of 27:196-205 DHBOA 27:191 DIBOA 27:191,195,196 DIM2BOA 27:191 DIMBOA 27:191,195,196 HBoA 27:191 HDMBoA 27:191 HMBoA 27:191 synthesis of analogues 27:205-207 TRBoA 27:191 2,4-Benzoxazocine derivatives 6:469 by ring expansion 6:469 Benzoxazocine derivatives 6:468-471 by ring construction 6:468-471 by ring destruction 6:468-471 by ring interconversion 6:468-471 from c~-narcotine N-oxide 6:468 synthesis of 6:468-471 1,5-Benzoxazocine N-oxide 6:472 1,6,5-benzodioxazonine from 6:472 thermolysis of 6:472 Benzoxazolidone derivative 12:164,166 boron enolate of 12:164,166 C4-alkylation by 12:164,166 stereoslective 12:164,166 Benzoxazolin-2(3H)-ones 27:193 4-ABOA 27:193 BOA 27:193 4-C1-DMBOA 27:193 5-C1-DMBOA 27:193
101 DMBoA 27:193 MBOA 27:193 Benzoxazolin-2-one 7:191,192 2(3H)-Benzoxazolone 23:342 Benzoxazolones 23:342 2,5-Benzoxazonine 6:468-471 carbocation intermediate in 6:473 derivatives of 6:476,47 photosolvolysis of 6:475,476 synthesis of 6:473 X-ray analysis of 6:476,477 Benzoxicins 5:798;10:210 N-Benzoyl Cls-phytosphingosine 18:461 Benzoyl compounds 30:236 structure of 30:236 N-Benzoyl phytosphingosine 18:462 3-Benzoyl propionic acid 10:406 Benzo yl- 1,2:5,6-di- O-isoprop ylidene- aD-3-O-glucofuranose 6:285,286 4-O-Benzoyl- 1,2-cyanoethylidene-ot-Lrhamnose 14:242 Benzoyl- 16-(+)-N-acetoxycycloxobuxidine-F 2:200,201 Benzoylation 1:415,417,289,290,341 N-Benzoylbaleabuxidine-F 2:205 N-Benzoylbuxidienine 2:205 N-Benzoylcarbamate 14:569 cyclization of 14:569 from 2,3-epoxy alcohol 14:569 2-oxazolidinone from 14:569 N-6-Benzoyldeoxyadenosine derivatives 4:278 N-B enzoyldihydrocyclomicrophylline-F 2:207 Benzoylgomisin O 26:197 5-( 1-Benzoylindol-3-ylmethyl)pyrrolidinone 13:130,131 Benzoylisogomisin O 26:247 N-B enzoyl-iso-serinate 12:223,225 O-Benzoylnormacusine 13:386 1-B enzo yloxy- 3-[ ( 3- guaiazulenyl) methyl]-5-isopropyl-8-methylazulene 14:324 N-Benzoylpyrrolidinone 13:121 N-Benzoylpyrrolinone 8:212,213 synthesis of 8:212,213 Benzthiazole 25:896
(R)-(+)-Benzyl 1-(2-methoxy)-naphthyl sulfoxide 10:684,685 ot-Benzyl 1-asparaginate 12:121 (S)-Benzyl 2,3-epoxypropyl ether 10:410,411 from D-mannitol 10:410,411 Benzyl 2-O-methanesulfonyl-13-Darabinopyranoside 14:50 Benzyl 5-amino-5-deoxy-2,3-Oisopropylidene-ot-D-mannofuranoside 10:541 Benzyl benzoate 28:416 against Psoroptes 28:416 against Sarcoptes mites 28:416 against Sarcoptes scabiei 28:416 effectiveness of 28:416 in mange control 28:416 Benzyl bromide 22:228 ot-Benzyl glycosides 6:390-395 of N-acetylmuramic acid methyl ester 6:395,399 of MurMAc 8-1actones 6:390-395 reactions of 6:390-395 N-Benzyl lactam (CGP-42700) 12:388 Benzyl sulfinylcarbamate 1:23 Benzyl tolyl sulfone 11:349 1-Benzyl- 1,2,3,4-tetrahydroisoquinolone alkaloids 10:683-685 B enzyl-2,3-anhydro-[3-D-ribopyranoside 14:50 4, 0-Benzyl-2,3-O-bis (methoxy methyl)-L-threitol 11:233 4-O-Benzyl-2,3-O-isopropylidenethreose 10:128-130 1-Benzyl-2,6-dicyanopiperidine 6:433 alkylation of 6:433 decyanation of 6:433 2,6-dialkylpiperidine s from 6:433 6-O-(2- O-B enzyl- 3-de oxy- 3- etho xy carbonyl-amino-4,6-O-isopropylidene-a-D-glucopyranosyl)-N, N'diethoxycarbonyl-2-deoxystreptamino 14:145 1-Benzyl-3-methylnaphthalene 30:217 formation of 30:217 from phenylacetone 30:217
102 1-Benzyl-3-methylnaphthalene 30:217 formation of 30:217 from phenylacetone 30:217 Benzyl-3-oxohexanoate 12:293 with 3-(1-A~-pyrroliniumyl) propanal 12:293 Benzyl-4,6-O-benzylidene-3-deoxy- [3D-ribo-hexopyranoside 14:11,12 synthesis of 14:11,12 3-O-Benzyl-4-O-methyl-dopamine 22:490 Benzyl-5-deoxy-5-(ethyl phosphinothioyl) 3-O-compounds 6:374,375 (+)-8-O-Benzyl-6-deoxy-castanospermine 12:346 6-Benzyl-9-(3,4-anhydro-c~-ltalopyranosyl)a-denine 4:233,234 (R)-( ct-methylbenzyl)B enzylamide 22:286 6-Benzylamino-9-(2-acetamido-2deoxy- f3-D-glucopyra-nosyl) purine 4:238 6-Benzylaminopurine (BAP) 4:227,238; 7:90,94,95 O-Benzylation 12:327 Benzylation 6:268-270,287,288 N-Benzylation 7:41-43 of 1,4-dideoxy- 1,4-imino-Lallitol 7:41-43 Benzylbenzoate 9:399 Benzylcarbamate prodrug HMR 1826 21:176,177 preclinical development of 21:176,177 O-Benzyldiscretine 14:776,777 fagaronine from 14:776,777 Benzylhistamine 26:119 Benzylic hydroperoxide rearrangement 3:316-319 3,5-O-Benzylidenation 12:52,53 of (9S)-9-dihydroerythronolide A 12:52,53 3-Benzylidene camphor 4:663,664 Benzylidene glycal 10:344 N-Benzylideneaniline 10:679,680 2,4-O-B enzylidene-D-threose 6:354 (1R)- 1-[(dimethoxy) phosphinyl]-Dthreitol from 6:354
4,6-O-Benzylidene-ct-D-glucopyranoside 14:157 N-Benzylipiperidine 19:35 Benzylisoquinoline alkaloids 6:472; 24:895-897;25:541 inhibitory effect on tube formation 24:895-897 isoquinoline 25:530 papaverine 25:541 Benzylisoquinoline derivatives 6:477,478,480 dibenz[d,f]azonine derivatives from 6:477,478,480 Benzylisoquinolines 3:422 synthesis of 3:422 3-O-Benzylisovanillin 22:490 N-Benzyl-L-glutamic acid 12:312 Benzyllithium 8:6 alkylation of 8:6 Nb-Benzyloxotryptamine 26:118 2-Benzyloxy glucals 10:346 Benzyloxy(benzyloxycarbonyl)methyl)trimethylphosphonium 30:441 (-)-9-Benzyloxy-9-demethyl-7methoxynogarene 14:82 Benzyloxycarbonylation 12:478 N-Benzyloxycaronyl- 1-proline methyl ester 12:295 exo- 15-Benzyloxyhobartine 11:299,300 15-Benzyloxyhobartine derivative 11:298,299 Benzyloxyisoflavone 27:499 Benzyloxymethyl chloride 6:561 a-(2-Benzyloxypropionyl)-butyrolactone 8:287 N-Benzyl-p-toluensulfonamide 12:323 5-Benzylpyrrol-2(5H)-ones 13:113 4-O-Benzylresacetophenone 27:499 Benzylstrictosidine 26:117 Benzyltetrahydroisoquinoline 18:72,76; 25:824 Benzylthiocrellidone 25:832 N-Benzyltrifluoroacetamide 14:553,554 Benzylvincoside 26:117,138 Benzyne cyclization 4:541-551 Benzyne reaction 16:514 Beogradolide A 27:550 Beogradolide B 27:550 Berbamine 21:57,79,96,98,102;25:472
103
Berbamine alkaloids 25:476 Berbamunin 20:292 Berberidaceae 21:3;27:754 Berberideine 20:265 Berberine 1:212;13:660;21:57,84,96,97, 102,108,109,733 ;22:27,35 ;25: 528; 26:305,821,822,823 APT spectrum of 5:42,43 biosynthesis of 11:201-204 t3C-NMR spectrum 5:44 8,14-cycloberbine from 1:211 from Berberis sp. 7:88 from Berber& vulgaris 13:660 1H-NMR spectrum of 5:40 INEPT spectrum of 5:43,44 Berberine bridge enzyme (BBE) 11:204 Berberis koetineana 11:202 Berberis sp. 7:88 berberine from 7:88 Berberis stolomifera 20:292 Berberis vulgaris 13:660;25:476 Berdy database 19:759 Beresklet 23:655 (+)-[3-cis-Bergamotene 16:235 cis-Bergamotene 16:235,236 c~-Bergamotene 21:607 [3-Bergamotene 26:459 Bergapten 20:497;22:522,539 from Limonia acidissima 20:497 Bergenin 13:660;23:536;27:395 from Ardisajaponica 13:660 regioselective hydroboration of 13:135 Berhamine 21:80 Bersama abyssinica 22:514 for epilepsy 22:514 exo-Bervicorffln 19:126 Bestatin 12:412,434,493 Beta mannosidase I 22:30 Beta vulgaris 15:3;20:721,731,740; 21:666 Betacyanin alkaloid 27:745 Betaenone B 4:601,602,621,17:475 Beta-eudesmol 24:883-887 potentiating effects on neuromuscular blocking action 24:883-887 Betagarin 22:458
Betaine 1:89,92,752,539 Betalaines 20:724,740 Betanidine 20:724-740 Betanine 20:724,731;26:305 Betavulgarin 22:458 Betavulgarosides from 21:666 Bethanecol 25:612 Betula davurica 26:895 Betula ermanii 26:895 Betula maximowicziana 26:895,899 Betula ovalifolia 26:899 Betula pendula 17:361,366 Betula platyphylla 17:361 Betula platyphylla var. japonica 26:255, 887,895,899 Betula sp. 17:358.361 ;26:894,905 Betulaceae 17:358,359,364,366;23:403 Betulatetraol 26:895 Betulifol A&B 26:568 Betulin 7:189,293;22:105;25:60 B etulinaldehyde-3 [3-yl-caffeate 30:646 2D NMR of 30:646 NOESY spectrum of 30:646 stereochemistry of 30:646 structure of 30:646 Betulinic acid 7:189,507;21:664; 25:59-61,66,541 ;26:813,814;28:17, 40,62;29:571,574 anti-microbial activity of 28:62 cytotoxic activity of 28:17 inhibition of Candida albicans aspartic protease 29:571 inhibition of HIV- 1 protease 29:571 Betulinic acid (lupane triterpene) 29:578 effects on aminopeptidase N 29:578 effects on HIV-1 protease 29:574 Betuloside 20:116 ent-Beyer- 15-en- 17,19-ol 30:714 structure of 30:714 Beyerane 15:252 Beyerane ent-3[3-Hydroxy- 15-beyeren2-one 29:100 activity in EBV assay system 29:100 BF3 rearrangement 5:782,783
104 BF3-mediated method 11:117 Bgt A 21:750-754 clinical trials of 21:754 pharmacological study of 21:748,752-754 of BgtA 21:750-754 B haringine 5:174,175 Bhesa paniculata 23:652 Bhilawainol 9:318 Bhimberine 9:170,172,173 BHT 25:792 5,5'-Bi(1,3-di-bromoazulene) 14:334 7,7'-Bi(3-bromoazulene)- 1,1' (7H,7H')dione 14:342 Bianco 29:487 valienamines synthesis by 29:487 9'-Bianthracene-10,10' (9H, 9'H) diones 11:125,1269 from 1,9-anthracenediols 11:125,126 8-Biapigenin 22:645 13,118-Biapigenin 22:662;30:618 structure of 30:618 Bicarbocyclic bridged systems 6:65-74 Bicarbocyclic fused system 6:5-38 Bicarbocyclic lactone 6:80 Bicuculline 21:69,733;22:26,27,508; 26:868 Bicyclic C-glycoside 30:470 cleavage of 30:470 Bicyclic cis-glycols 8:245,246 Bicyclic diterpene 8:220 Bicyclic diterpenoid glycosides 23:158 Bicyclic enone 14:678,679. taxodione from 14:678,679. from monocyclic ketones 10:311-313 Bicyclic gephyrotoxins (indolizidines) 11:244 Bicyclic keto ester 14:509 Bicyclic keto-acid 12:283 Bicyclic lactones 12:150 Bicyclic lupine alkaloids 27:267 Bicyclic olefin 11:371 Bicyclic phloeodictine B 28:688 antibacterial activity of 28:688 cytotoxic activity of 28:688 Bicyclic triene 6:79
Bicyclic [3-1actam 12:172,173 by Diels-Alder reaction 12:172,173 from cyclic imines carboxylic acid 12:117 from 2H-4H, 1,3-dioxin derivatives 12:160,161 synthesis of 12:172,173 Bicyclo [2.2.1] heptanes 8:415 synthesis of 8:415 Bicyclo [2.2.2] octane 6:70,71 (+)-sanadaol from 6:70,71 by double Michael addition 8:422 from Li-cyclohexadienolates 8:422 from c~,[3-unsaturated esters 8:422 synthesis of 8:412-422 B icyclo [2.2.2 ] octane ring 8:166 Bicyclo [3.2.1] octadione 8:161,162 synthesis of 8:161,162 Bicyclo [3.2.1] octane 8:420,421,40; 12:22 Bicyclo [3.2.1] octanone 6:78,79 Bicyclo [3.2.1 ] octenes 10:317,318 from bicyclo [3.3.0] octanones 10:317,318 Bicyclo [3.2.1] system 12:86 Bicyclo [3.2.1] hemithioacetal 8:205 Bicyclo [3.2.2] nonadienone 1:567 Bicyclo [3.2.2] piperazinedione 12:71 synthesis of 12:71 Bicyclo [3.2.2] system 12:85 Bicyclo [3.3.0] octane 10:315 spiro [4.5] decane from 10:315 cis-Bicyclo [3.3.0] octanes 13:4 Bicyclo [3.3.0] octanones 10:310,311, 317,318 Bicyclo [3.3.1] nonane 3:95; 6:65-69,224 conformation of 3:95 fragmentation of 3:74 Bicyclo [3.3.1] nonyl transition state 4:447;10:317,318 Bicyclo [4.2.2] mesylate 12:80 Bicyclo [4.2.2] ring system 12:64,65 Bicyclo [4.3.0] non- 1-en-3-one 10:310
105
Bicyclo [4.3.0] nonane 6:5-11;11:230 Bicyclo [4.3.1] dec-2-en-7-one 6:69 by Grob fragmentation 6:69 by intramolecular [2 + 2] photocycloaddition 6:69 synthesis of 6:69 Bicyclo [4.3.1] decane group 6:69-72 Bicyclo [4.3.1] decanone 6:70 nakafuran-9 from 6:70 synthesis by four carbon polar annulation 6:17,21 Bicyclo [4.4.0] decane 6:10,235 Bicyclo [4.4.1] undecane group 6:72-74 Bicyclo [4.4.1] undecanone 12:238,244 Bicyclo [5.1.0] ontanone 12:243 Bicyclo [5.2.2] piperazinedione 12:84, 85 synthesis of 12:84,85 Bicyclo [5.3.0] decane group 6:11,12 Bicyclo [5.3.1] undecane unit 12:179 Bicyclo [5.4.0] undecane group 6:29-33 Bicyclo [5.4.0] undecanone 12:249 Bicyclo [6.2.1] undecane 12:193 Bicyclo [6.3.0] undecane group 6:33-38 Bicyclo [6.3.0] undecane skeleton 1:568 Bicyclo [6.3.0] undecanone 6:36 from bicyclo [3.2.0] heptanone 6:36 poitediol from 6:36 Bicyclo [6.4.0] dodecyl structures 12:212 Bicyclo[2.2.2] ring system 28:363,370 construction of 28:363,370 Bicycloboranonane 13:1359Bicyclogermacrene 21:282;27:573 Bicyclohumulenone 2:278,279; 8:183-186 from Plagischila acanthophylla subsp, japonica 8:183 synthesis of 8:183-186 Bicyclomycin 12:63 antibiotic activity of 12:63 antimicrobial activity of 12:41 toxicity of 12:63 Bicyrtes ventralis 5:223,224,253 Biczamycin 12:63 Bidens aurea 25:614 Bidens campthotheca 29:682
Bidentatin 23:609,610 13C-NMR data of 23:610 IH-NMR data of 23:610 Bidesethylchloroquine 25:344 Bidesmosides 26:813 Bidesmosidic dammarame oligoglycosides 24:144 Bidesmosidic saponins 7:429,432; 24:133,134,144;27:664,675,671 sandrosaponin 27:671 Bidesmosidic triterpene saponin 24:149 Biellmann coupling 10:6-10 Biemma sp. 25:703 Biflavones 22:644;25:31,125,126,127, 539 amentoflavone 25:539 bilobetin 25:539 sequoiaflavone 25:540 ginkgentin 25:540 Biflavonoids 5:468,756-758;30:207 antinocicieptive effect of 30:207 Biflorin 3:450,451 from Eremophila latrobel 15:258 synthesis of 3:450,451 Biflustra perfragilis 17:81,89,91 ; 21:265 ;25:825 ;28:619-620 2-methyl-6,7-di(methylthio)-2Hisoquinoline-3,5,8-trione from 28:619 2-methyl-6-methylthio-2Hisoquinoline-3,5,8-trione from 28:619 Bifurcanol 20:26 Bifurcaria bifurcata 18:713 Bignoniaceae 7:406 Biguaiazulene 14:315,3193,3'5,5'-Biguaiazulene-3,3' (5 H, 5'H)-dione 14:320 Biguanides 21:459,488 Bigutol 21:205 BII cell bioassay 29:33-38 abutasterone activity in 29:34 24-epi-abutasterone activity in 29:36 ajugalactone activity in 29:34 ajugasterones activity in 29:34 amarasterone A activity in 29:34 atrotosterones activity in 29:34
106 bombycosterol activity in 29:34 calonysterone activity in 29:34 canescesterone activity in 29:34 castasterone activity in 29:34 24-epi-castasterone activity in 29:36 cheilanthone B activity in 29:34 cyasterones activity in 29:34 dacryhainansterone activity in 29:34 2-dansyl-20-hydroxyecdysone activity in 29:34 22-dehydro- 12-hydroxycyasterone activity in 29:34 22-dehydro- 12-hydroxynorsengosterone activity in 29:34 22- dehydr o- 20-iso-ecdysone activity in 29:35 3-dehydro-2-deoxyecdysone: (silenosterone) activity in 29:34 3-dehydro-2-deoxyecdysone 22acetate activity in 29:34
2-dehydro-3-epi-20-hydroxy-
ecdysone activity in 29:34 24(28)-dehydroamarasterone B activity in 29:34 24(28)-dehydromakisterone A activity in 29:35 25 (25 )- dehydropre cyasterone activity in 29:35 2-dehydroshidasterone-22glucoside activity in 29:35 14-dehydroshidasterone activity in 29:35 14-deoxy( 14 [3-H)-20-hydroxyecdysone activity in 29:35 3-deoxy- 113,20-dihydroxy ecdysone activity in 29:35 (20R)22-deoxy-20,21-deoxyecdysone activity in 29:35 2-de oxy- 20,26- dihydroxyecdysone activity in 29:35 22-deoxy-20-hydroxyecdysone (taxisterone) activity in 29:35 2-deoxy-20-hydroxyecdysone 22benzoate activity in 29:35 (14(x-H) 14-deoxy-25-hydroxydacryhainansterone activity in
29:35 2-deoxyecdysone-25-glucoside activity in 29:35 2-deoxyecdysone-3,22-diacetate activity in 29:35 25-deoxyecdysone activity in 29:35 (5 c~-H)2-deoxyintegristerone A activity in 29:35 5-deoxykaladasterone activity in 29:35 2-deoxypolypodine B 3-glucoside activity in 29:35 25,26-didehydroponasterone A activity in 29:35 2,22-dideoxy-20-hydroxyecdysone activityin 29:35 (5 [3-H)-dihydrorubrosterone 29:35 dihydrorubrosterone 17-acetate activity in 29:35 dihyropoststerone tribenzoate activity in 29:35 (22S)20-(2,2'-dimethylfuranyl) ecdysone activity in 29:35 ecdysone 2,3-acetonide activity in 29:36 ecdysone 22-hemisuccinate activity in 29:36 ecdysone 6-carboxymethyloxime activity in 29:36 3-epi-22-iso-ecdysone activity in 29:36 20-iso-22-epi-ecdysone activity in 29:37 25-fluoropolypodine B activity in 29:36 25-fluoroponasterone I3 activity in 29:36 for ecdysteroid-like activities 29:33 22,23-di-epi-geradiasterone activity in 29:35 geradiasterone activity in 29:36 28-homobrassinolide activity in 29:36 iso-homobrassinolide activity in 29:37
107
6f3-hydroxy-20-hydroxyecdysone activity in 29:36 513-hydroxy-25,26-didehydroponasterone A activity in 29:36 5 [3-hydroxyabutasterone activity in 29:36 25-hydroxyatrotosterone B activity in 29:36
3-epi-20-hydroxyecdysone
(coronatasterone) activity in 29:36 20-hydroxyecdysone 22-benzoate activity in 29:36 20-hydroxyecdysone 22hemisuccinate activity in 29:36 20-hydroxyecdysone 2-~-Dglucopyranoside activity in 29:36 20-hydroxyecdysone 3~-Dxylopyranoside activity in 29:36 20-hydroxyecdysone 6-carboxymethyloxime activity in 29:36 ( 5(x-H)20-hydroxyecdysone activity in 29:36
14-epi-20-hydroxyecdysone
activity in 29:36 26-hydroxypolypodine B activity in 29:36 5 [3-hydroxystachysterone C activity in 29:36 inokosterone 26-hemisuccinate integristerone A activity in 29:37 (25R/R) inokosterone-20hydroxy-ecdysone activity in 29:36 1-epi-integristerone A activity in 29:36 isostachysterone C activity in 29:37 kaladasterone activity in 29:37 5Gt-ketodiol activity in 29:37 limnantheoside C activity in 29:37 24-epi-makisterone A activity in 29:36 14-methyl- 12-en- 15,20-
dihydroxy-ecdysone activity in 29:37 14-methyl- 12-en-shidasterone activity in 29:37 24-methylecdysone (20-deoxymakisterone A) activity in 29:37 muristerone A activity in 29:37 29-norcyasterone activity in 29:37 29-norsengosterone activity in 29:37 paxillosterone 20,22-p-hydroxybenzylene acetal activity in 29:37 pinnatasterone activity in 29:37 podecdysone B activity in 29:37 polypodine B activity in 29:37 polyporusterone B activity in 29:37 ponasterone A 22-hemisuccinate activity in 29:37 ponasterone A 3[3-D-xylopyranoside activity in 29:37 ponasterone A 6-carboxymethyloxine activity in 29:37 ponasterone A dimer activity in 29:37 poststerone 20-dansylhydrazine activity in 29:37 punisterone activity in 29:37 rapisterones activity in 29:37 rubrosterone activity in 29:37 sengosterone activity in 29:37 shidasterone activity in 29:37 sidisterone activity in 29:37 silenoside A (20-hydroxyecdysone 22-galactoside) activity in 29:37 silenoside C (integristerone A 22galactoside) activity in 29:38 silenoside D (20-hydroxyecdysone3-galactoside) activity in 29:38 stachysterones activity in 29:38 213,313,20S,25-tetrahydroxy-25fluoro-5 [3-cholest-8,14-dien-6one activity in 29:38
108
2ot,3 ot,22S,25-tetrahydroxy-5acholestan-6-one activity in 29:38 213,3[3,6c~-trihydroxy-5[3cholestane activity in 29:38 turkesterone 11 c~-acetate activity in 29:38 turkesterone 11 ot-arachidate activity in 29:38 turkesterone 11 c~-butanoate activity in 29:38 turkesterone 11 c~-decanoate activity in 29:38 turkesterone 11 a-hexanoate activity in 29:38 turkesterone 11 c~-laurate activity in 29:38 turkesterone 11 a-myristate activity in 29:38 turkesterone-2,11 c~-diacetate activity in 29:38 turkesterone-2,22a-diacetate activity in 29:38 viticosterone E activity in 29:38 Bijvoet difference method 13:434 Bile alcohols 17:207,212 Billheimer method 9:464 Bimolecular [67t+47t] tropone diene 12:241 cycloaddition of 12:241 Bimolecular conjugate addition 24:768 Bimolecular cyclization 24:769 BINAL-H 16:377 SBinandkatsuim A 20:276 BINAP 13:72 (S)-BINAP 19:29 BINAP-Ru-catalyst 4:439 in asymmetric hydrogenation 4:439 Binary indole alkaloids 5:140-151 Binatriol 30:710 structure of 30:710 Binding assay 30:494 of calf-thymus vitamin D receptor 30:494 Binding bioactivity 30:813 of [Tyr)Me)2-Phe] peptides 30:813
of d-Tyr(Me)2-d-Phe-G-V-VNH2 30:813 of d-Tyr(Me)2-d-Phe-NH2 30:813 of d-Tyr(Me)2-Phe-G-V-V-NH2 30:813 of d-Tyr(Me)2-Phe-NH2 30:813 of Tyr(Me)2-d-Phe-G-V-V-NH2 30:813 of Tyr(Me)2-d-Phe-NH2 30:813 of Tyr(Me)2-Phe-G-V-V-NH2 30:813 of Tyr(Me)2-Phe-NH2 30:813 Binding pocket 27:33 Bioactive 3-deoxy-ulosonic acids 30:419 recent advances in 30:419 Bioactive compounds 24:954-956; 28:3,4,9,16,22 from Broussonetia genus 28:3 from Broussonetia kazinoki 28:4,9 from Broussonetia papyrifera 28:16,22 of EMIBD 24:954-956 Bioactive constituents 23:552;30:559 of genus Hernandia 30:559 of monotoideae 23:552 Bioactive diterpenes 24:175-213 Bioactive marine natural products 21:293 biosynthesis of 21:293 Bioactive metabolites 21:364;23:185 from Indo-Pacific marine invertebrates 21:251 from soil-borne fungi 21:181 of symbiotic marine microorganisms 23:185 structure-activity relationships of 21:251 Bioactive monoterpenoids 28:426 carvacrol as 28:426 carvomenthenol as 28:426 carvone as 28:426 citronellol as 28:426 eugenol as 28:426 geraniol as 28:426 perillyl alcohol as 28:426 4-terpineol as 28:426
109
thymol as 28:426 Bioactive natural products 23:488 Chinese medicinal plants 21:729 from bioactive natural products 21:729 from Chinese medicinal plants 21:729 Bioactive oleanane glucurnoides 25:89 Bioactive peptide 25:367 Bioactive saponins 21:633 bioactivity of 21:744 from plants 21:633 licochalcone A 21:744 Bioactive secondary metabolites 23:185-231 from Okinawan sponges 23:185-231 from tunicates 23:185-231 Bioactive terpenes 24:175-213;30:635 from celastraceae 30:635 from Wieland Miescher ketone 24:175-213 Bioactivity 21:744;23:335;24:933972;25:668;26:909,911-914,926; 27:348;30:233,516,520 8'-hydroxyabscisic acid 27:349 bioactivity of 27:348 of 8'-hydroxyabscisic acid 27:349 of carotenoids 30:516,520 of cocumarins 23:335 of EMIBD 24:954-956 of endophytic fungi 24:933-972 of HIRE 24:951-954 of labiatae flavonoids 30:233 oflicochalcone A 21:744 of nitric oxide 26:926 of phenolic compounds 25:668 Bioantimutagenic 21:641 Bioassay-directed fractionation 30:157, 591 of Ozoroa insignis 30:157 use of chromatographic techniques in 30:591 Bioassays 24:863-869;30:801 allelopathy 24:867 anti-feedant 24:866 anti-fungal green house 24:864 anti-inflammatory 24:869
anti-microbial 24:863,864 antioxidant 24:868 brine shrimp 24:864,865 caterpillar data 24:866 corn earworm 24:865 cytotoxicity 24:867 forest Tent caterpillar 24:865 Gypsy moth 24:865 herbicidal 24:867 insecticidal 24:866 mosquitocidal 24:864 neuraticidal 24:866,867 statistical analysis of 24:866 tobacco hornworm 24:865 topoisomerase inhibitory 24:867, 868 Bioautographic methods 21:257 Bioautographic TLC assays 26:255 Bioavailability 23:776;27:312,314 of nutrients 27:312,314 of phenolic antioxidants 23:746, 775 Biochanin A 22:446 Biochemical assays 30:226 activity of natural polyphenols in 30:226 Biochemical studies 27:393 of natural products 27:393 Biocidal activity 21:598 Biocides 25:668 Biocontrol activity 21:187 Biocontrol agents 21:181 Bioconversion 17:470 using Morus alba cell 17:470 Biofilms 17:100 Bioflavours 25:125,128,129,294,300, 329,401,659,661,662 de novo synthesis of 25:128,129, 294,300,329,401,659,661,662 Biogeneration 13:295-345 of flavors 13:295-345 Biogenesis 23:204,211,253,255,395453 ;26:141,142,313,314,405,465, 552,1054;27:515 for Nb-C(21) secocuran alkaloids 26:1054 of diterpenes 26:465 of ecteinascidins 23:253,255
110 of ellagitannin oligomers 23:395-453 of F r a x i n u s ornus 26:313,314 of manzamenone K 23:204,211 of sclareol 26:405 of secologanin type alkaloids 26:142 of some iridoids 26:141 of swainsonine 27:515 of the resveratrol oligomers 26:552 total synthesis of 24:588-605, 656 Biogenetic aspects 21:129 kopsirachin as 21:129 Biogenetic precursor 16:301 ;30:622 of allamandicin 16:301 of plumericin 16:301 of xanthones 30:622 Biogenic amines 15:328 Bioinsecticides 15:381 Bioisosteric replacement 21:257 Biological action 24:875 as anti-angiogenesis 24:875 as anti-hyperglycemic 24:875 as anti-inflammation 24:875 as anti-proliferation 24:875 in blood glucose regulation 24:875 in blood vessel relaxation 24:875 in cardiotonicity 24:875 in neuromuscular blocking 24:875 in smooth muscle relaxation 24:875 Biological activities 21:132,148,162, 223,236,23 8,263,265,269,284,297, 366,388,390,410,419,421,431,571, 578,591,598,601,603,620,694;23:63, 93,95,108,111,129,126,107-152,153, 158,179,267,271,285,395-453, 455-485,491,497,642-643 ;739;24:25, 353-376;799,845;27:178,185-225, 332,377,431,421,443,659693,778, 801,924;28:109,212,228,229,340; 29:743 ;30:4,26,172,175,200,224, 303,310,395,404,483,484,485,495, 496,497,499,562,588,603,637,831, 840,843
acaricidal 24:799 allelopathic 24:845 anti-bacterial 24:25 antibiotic 24:799 anti-feedant 24:845 anti-fungal 24:25,799 anti-inflammatory 24:799 antimalarial 30:561 anti-microbial 24:845 anti-oxidant 24:845 antioxidant 30:561 antiplatelet aggregation 30:560 anti-secretory 24:799 anti-serotonergic 24:799 anti-tumor 24:845 chirality in 7:3-28 choleretic 24:799 cytotoxic 24:799,845 cytotoxic 30:560,561 Decumbenine B 21:735 herbicidal 24:799 H e r n a n d i a species 30:588 in black-sugar 27:409,410 in fat cell 27:393 in human osteosarcoma ~ 30:497 m human osteosarcoma 2 30:497 m red wine 27:430 zn vivo 30:499 inhibition of enzyme 24:845 insecticidal 24:25,799,845 isolation of 4:243 molluscicidal 24:799 of(-)-selin-11-en-4c~-ol 14:450, 451 of (+)-caffeic acid 27:421 of (+)-chlorogenic acid 27:421 of (+)-compactin 11:335,336 of (+)-mevinolin 11:335,336 of (EFEa) 30:831 of[3-glucans 23:107,111,115,135 of 14et-hydroxy-MFA 28:340 of 1-methoxyficifolinol 28:229 of 1-methoxyphaseollidin 28:229 of lcc,25-(OH)2D 30:495 of 1et,25(OH)2D analogues 30:495 of la,25(OH)2D3 30:496 of lot,25(OH)zD4 30:499
111 of 3'-(7,7-dimethylallyl)kievitone 28:228 of 3-hydroxyglabrol 28:228 of 3-hydroxyparatocharpin C g 28:228 of 3-O-methylgancaonin P 28:229 of 4'-O-methylglabridin 28:229 of 6-prenyleriodictyol 28:229 of 6-prenylnaringenin 28:229 of 8-(y,y-dimethylallyl)wighteone 28:228 of 8-prenyleriodictyol 28:229 of abscisic acid 27:331,352 of acetyl-N-Ser-Asp-Lys-Pro 27:806 of agrimoniin 23:398 of agrimoniin 23:398 ofalbanin D 28:229 ofalbanin F 28:230 ofalbanol A 28:230 ofalbanol B 28:229 of alvaxanthone 28:229 of amicoumacins 15:410-412 of Angelica shikokiana 27:429 ofangustone B 28:228 ofantlarone B 28:229 ofantlarone F 28:229 ofantlarone G 28:229 ofantaarone H 28:229 ofannarone I 28:229 ofannarone J 28:229 of Artemisia montana extracts 27:420 of Artemisiae herba 27:413 of artobiloxanthone 28:229 ofartonin E 28:229 of astragalus L. genus 27:443 of avermectins 12:7-9 ofbaciphelacin 15:409,410 of baicalein 27:433,435 of balanol 27:869 of bavachalcone 28:228 of Benzo [c]phenanthridine alkaloids (QBA) 27:819 ofbenzoxazinoids 27:211 ofbenzoxazinones 27:185-225 of bis-indolyl maleimides 12:384-399,133,91
of bombesin 27:797 of bombsin 27:797 ofbroussochalcone B 28:228 ofbroussoflavonol B 28:229 ofbroussoflavonol C 28:229 ofbroussoflavonol E 28:230 of Bupleurum rigidum 27:693 ofBupleurum rigidum L. 27:659 of capsaicin 30:200 of chitosan 27:404 of cholesterol oxides 24:351-398 ofcudraphenone B 28:230 ofcudraphenone D 28:230 of cycloartobiloxanthone 28:230 ofdecumbenine B 21:735 ofdehydroglyasperin C 28:228 of discodermolide 30:4 of dynorphins 27:801 of echinatin 28:228 of edudiol 28:228 of EFE 30:840 of endorphins 27:801 of endotoxin-induced 27:435 ofenkephalins 27:801 oferythrinin B 28:229 of erythromycin 13:155-185 ofEscherichia coli 30:843 of essential oil 21:571 of essential oils 21:571-580,573 offlavonoids 23:739;27:431 of formaononetin 28:228 of free fatty acid 27:404 of fungal [3-glucans 23:108,111, 126 ofgancaoinm S 28:228 of gancaonm C 28:228 of gancaonm E 28:228 of gancaonm G 28:228 of gancaonm H 28:228 of gancaonln I 28:228 of gancaonln O 28:228 of gancaonan P 28:228 of gancaonan Q 28:228 of gancaonm R 28:228 of gancaonm U 28:228 of gancaonm V 28:228 of gancaonln Y 28:228 of garlic 23:468 of Geranii herba 27:413,415
112 of Ginkgo biloba 30:172 ofginsenoside Rgl 27:424 of glabranin 28:228 of glabranine 28:228 of glabrene 28:228 of glabridin 28:228 of glabrocoumarone A 28:229 of glabrol 28:228 of glisoflavanone 28:228 of [3-glucosidases 27:778 ofglyasperin A 28:228 ofglyasperin B 28:228 ofglyasperin C 28:228 ofglyasperin D 28:228 ofglyasperin J 28:228 ofglyasperin K 28:228 of glycycoumarin 28:228 ofglycyrdione A 28:228 of glycyrin 28:228 of glycyrol 28:228 ofglyinflanin A 28:228 of green tea 27:417,420 of Hernandia nymphaeifolia 30:562 of Hernandia species 30:562 of Hernandia voyronii 30:562 of heterophyllin 28:230 of hispaglabridin A 28:228 of hyperlipdaemia 27:405 of indolo [2,3-a] carbazole alkaloids 12:384-399 ofintermedeol 14:450,451 of isoalvaxanthone 28:230 of isoderrone 28:228 of isoglycyrol 28:228 of isoliquiritigenin 28:228 of ivermectin 12:8,9 ofkanzonol B 28:229 ofkanzonol G 28:229 ofkanzonol H 28:229 ofkanzonol P 28:229 ofkanzonol R 28:229 ofkanzonol S 28:229 ofkanzonol U 28:229 ofkanzonol V 28:229 ofkanzonol W 28:229 ofkanzonol X 28:229 ofkanzonol Y 28:229 ofkazinol B 28:230
ofkazinol E 28:230 ofkazinol F 28:230 ofkazinol N 28:230 of KB-1 28:229 of KB-3 28:229 of kumatakenin 28:229 ofkuwanon 28:212 ofkuwanon C 28:230 ofkuwanon G 28:230 ofkuwanon H 28:212 ofkuwanon M 28:212 ofkuwanon R 28:230 of ot-lapachone 29:743 of[3-1apachone 29:743;30:310 oflicochalcone A 28:229 oflicochalcone B 28:229 of licoflavonol 28:229 of licoisoflavanone 28:229 oflicoisoflavone A 28:229 oflicoisoflavone B 28:229 of licorice 27:425 of licoricidin 28:229 of licoricone 28:229 oflicorisoflavan A 28:229 of lipogenesis 27:393 of lipolysis 27:393 of macarangaflavanone B 28:229 of medicarpin 28:229 of medicinal plants 27:393,405 of microcystins 20:896,897 of monoterpenoid enantiomers 27:377 of montanin C 23:643 ofmoracein B 28:230 ofmoracin C 28:230 of morusin 28:212,230 of morusinol 28:230 of mulberrin 28:230 of mulberrochromene 28:230 of mulberrofuran B 28:230 of mulberrofuran G 28:212,230 of naringenin 28:229 of natural products 7:3-29; 27:393,405 of natural steroids 30:485 ofneointermedeol 14:450,451 of nocamycin 14:110 of nodularins 20:896,897 of non-sugar fraction 27:409,410
113 of norartocarpetin 28:230 of oligomeric compound 27:778 of Oolong tea 27:401 of opioid peptides 27:801 of organosulfar compounds 23:455-485 of organosulfur compounds 23:468 of oxydihydromorusin 28:230 ofparatocarpin L 28:229 ofphaseoluteone 28:229 of PI turnover inhibitors 15:461, 462 ofpinocembrin 28:229 of pironetin 30:26 of plasma glucose 27:412 ofpolyene macrolides 6:261 ofPolygonum sp. 27:405 of polyphenols 30:224 ofpolysaccharide (PS) 30:395 of Pseudopterogorgia sp 23:179 of pseudopterosins 23:154,158 of pyranocoumarin 27:429 of quassinoids 23:285-333 of quinones 30:303 of resorcinolic lipids 30:175 of resveratrol 27:430 ofrifamycin B 23:93 ofrifamycin P 23:95 ofrifamycin S 23:94 of saikosaponins 27:693 ofsanggenol C 28:230 ofsanggenol M 28:230 of sanggenon A 28:212,230 ofsanggenon B 28:230 ofsanggenon C 28:212,230 of sanggenon D 28:212 ofsanggenon M 28:230 of saponin 27:859 of Scutellariae radix 27:431 of self-inhibitors 9:222,238 ofsemilicoisoflavone B 28:229 of serum TC 27:420 of serum transaminase 27:415, 417,420,421 of serum triglyceride 27:404 of shinpterocarpin 28:229 ofsigmoidin A 28:229 ofsigmoidin B 28:229
ofsorocein F 28:230 of soyasaponins 27:399 ofspatane diterpenoids 6:39 of spatol 6:39 of sphingolipids 18:459,460 of Spirulina platensis 30:404 of staturosporine 12:399 ofstilbene derivatives 27:405, 409 of streptolydigin 14:108,109 of tannic acid 23:412 of tannin 23:442;27:413,416 of taxanes 11:4-6 of taxodione 14:667 oftenuifolin B 28:229 of tetracyclic pyridoacridine alkaloids 23:271 of tetrahydro-13-carbolines 23:267 of tetramic acid 14:107-110 of tetramic acid-containing compounds 28:109 ofteucjaponin A 23:642 ofteucjaponin B 23:643 of topozolin 28:229 of triterpenes 30:637 of tyrosine kinase inhibitors 15:447,449 of vitamin D analogues 30:485 of vitamin D 2 30:483,484 of vitamin D3 30:483,484 of vitamin D4 30:483,484 of vitamin D5 30:483,484 of vitamin D6 30:483,484 of vitamin D7 30:483,484 of wighteone 28:229 of xenocoumacins 15:408,409 spasmogenic 24:799 spasmolytic 24:799;30:561 stimulatory 24:845 trypanosomal 24:799 Biological activity alteration 24:897 by processing 24:897 Biological behaviour 21:161,169 of galactose prodrugs 21:161 of glucuronic prodrugs 21:169 Biological control 21:182 of soil-born phytopathogens 21:182
114
Biological control fungi 21:187 antifungal metabolities from 21:187 biological behaviour of 21:161 galactose prodrugs 21:161 glucuronic prodrugs 21:169 Biological Diels-Alder reaction 17:451 Biological effects 21:501,524 Biological evaluation 23:591-648 of Genus teucrium 23:591-648 Biological processes 30:420 ofulosonic acids 30:420 Biological properties 10:241-302;23:93; 28:518,519 of ansamycin antibiotic 23:93 of didemnins 10:241-302 of lipid A 28:519 oflipo-CCK 18:857-863 of lipo-gastrin 18:857-863 Biological raw materials 17:601 Biological response 23:12 Biological response modifiers (BRMs) 25:431,434,452-455 Biological role 27:224,225;30:422 of benzoxazinone acetal glucosides 27:224,225 ofbenzoxazinones 27:185-225 of 3-deoxy ulosonic acids 30:422 Biological screening 29:366 allocolchicinoid synthesis for 29:364 Biological significance 24:369 of cholesterol variation number (CVN) 24:351,368,369 biological significance of 24:369 Biological studies 28:35;30:561 of genus Hernandia 30:561 on Licania genus 28:35 Biologically active constituents 17:153; 23:662 of celastraceae 23:662 Biologically active diterpenoids 21:689 from Scoparia dulcis 21:689 Biologically active glycolopoprotein complex (G-90) 30:485,826 species of 30:826 Biologically active metabolites 23:649-738 of celastraceae 23:649-738
Biologically active precursor 23:63 ofdamavaricin D 23:63 of damavaricin C 23:63 Biology 21:364 of marine isocyanides 21:364 Biomedicine 30:827 Biomethylation 9:47 Biomimetic cationic polyene cyclization 12:456 Biomimetic cyclization 14:681-684 ofallylic alcohol 14:681-684 Biomimetic olefin cyclization 1:671-673 Biomimetic polyene cyclizations 7:131 Biomimetic synthesis 24:743 Biomineralization 25:335 of heme 25:334 of hemozoin 25:360 Biomphalaria glabrata 7:432435 ;23:537,849;25:785 Bio-organic chemistry 9:431-445 of ansamycin 9:431-445 of antibiotics 9:431-445 of mitomycin 9:431-445 Biopholaria glabrata 25:792 Biophysical studies 27:334 ofabscisic acid 27:334 Biopolymers 17:481 Bioquercetin 7:226 Biorational plant protectants 21:109 alkaloids as 21:109 Bioregulators 2:377-386 studies with 2:377-386 chiral synthesis of 6:537-566 Biosilica 25:717 BIOSIS 19:758 Biosynthesis 21:293;23:51,79;27:321; 29:295 abscisic aldehyde in 27:321 by Read and Vining 29:295 in Clitocybe subilludens 29:296 in Peniophora sanguinea 29:298 in Phleba strigosozonata 29:296 of ansamycins 23:51,79 of ascocorynin 29:296 of atromentin 29:296 of bioactive marine natural
115 products 21:293 of deoxylapachol 29:736 of ecdysteroids 29:5 of gingerol 23:848 ofisocyanide group 21:349 of isoprenyl- 1,4-naphthoquinones 29:735 oflapachol 29:734 oflawsone 29:736 of lignans 24:742-744 of macrolide antibiotics 29:322 of manool 25:253,254,259 of melanin 26:1019 of menaquinone- 1 29:736 of nitrogen compounds 29:328 of ortho-terphenylquinone phlebiarubrone 29:296 of polyhydroxy-p-terphenyl 29:295-297 of scopadulan-type diterpenoids 21:721-723 ofstreptovaricin D 23:64 of terphenyllin 29:296 of tetracyclines 29:312 ofthelephoric acid 29:296 of triterpenoids 22:97 of volucrisporin 29:295 of xylerithrin 29:298 zeaxanthin in 27:321 Biosynthetic pathways 24:846,847 for production of natural products 24:846,847 Biosynthetic studies 23:266,260 of[3-carbolines 23:260,266 Biota orientalis 25:275;29:102 Biotechnology 13:296,297,299 Biotic stress 23:741 Biotinylated gastrin 18:920 Biotinylated peptides 18:919 Biotoxicity 21:596 Biotransformation 23:3,5,42;24:74-76, 309-318 of benzosampangine 23:3,5,42 of cis-6fl-sesquiterpene 24:74,75 of 6fl-eudesmanolioes 24:76 Biotransformation rates 27:377 Bipendensin 9:256 from Afzelia bipendensis 9:256 Biperezone 20:273
Biphenyl ether,4,4'-diallyl-2,3'dihydroxybiphenyl ether 24:861 anti-fungal activity of 24:861 Biphenyls 23:342 3,3'-Biplumbagin 2:212,214,5:754 ~H-NMR spectrum of 2:227 Bipolar disorder 30:369 effect of circadian activity on 30:369 Bipolaris sorokiniana 4:647;9:238; 21:196,199 Bipolaris zeicola 27:498 2,3'-Bipyridyl alkaloids 5:753 Birch reduction 11:286 of o-toluidine 11:286 of 6-methoxy-l-tetralone 12:235 of 4-methoxytoluene 12:22-24 ofp-cresyl methyl ether 6:83,84 BIRD sequence 9:97,98 12,12'-Bis (11-hydroxycoronaridyl) 5:129 B is (6-formyl-4-hydroxy-2-(2'-n'pentytoxazol-4'-yl)-4-pyridon-3-yl] 25:841 4-Bis (8-hydroxyquinolin-4-yl)butyrolactone 5:7533, (3R,4R)-3,4-bis (Benzyloxy) succinic anhydride 12:295 Bis (di-isoamyl) borane reduction 9:366 Bis (EDTA-DISTAMYCIN) phenoxazone 5:570 Bis (trimethylsilyl) ethylene glycol 1,3-dioxolane formation 1:584 Bis (trimethylsilyl)- 1,2-ethanedithiol 1,3-dithiolanes 1:584 reaction with aldehydes 1:584 reaction with ketones 1:584 Bis allylic bromide 8:16 Bis indole alkaloids 2:370371,387,389, 390,394,398 3'-Bis(2-cyanoethoxy) phosphoryl group 14:291,292 branched RNA from 14:291,292 2'-Bis(2-cyanoethoxy) phosphorylation 14:299,302 Bis-(3,7-diisopropyl- 1-azulenyl) ketone 14:340 Bis(bibenzyls) 2:103, 2:113
116 2,5-Bis(dimethylamino) benzoquinone 13:434 Bis-(EDTA-distamycin) fumaramide 5:569
[Bis(trifluoroacetoxy)iodo]benzene
30:439 as reagent 30:439 2,4-Bis-(trimethylsiloxy)-furan 13:451 Bis(trimethylsilyl) acetylenes 14:473 Bis(trimethylsilyl) butadiyne 14:473 Bis- 1-oxaquinolizidne macrocycles 24:606 structures of 24:606-609 11(15---~1), 1 l(10--~9)Bisabeo taxane 20:80,107 2,10-Bisaboladie- 1-one 26:861 Bisabolane 25:848 Bisabolane xanthorrhizol 29:87 activity in COX assaysystem 29:87 activity in iNOS assay system 29:87 Bisabolane: ar-turmerone 29:87 activity in COX assay system 29:87 activity in iNOS assay system 29:87 Bisabolane: [3-turmerone 29:87 activity in COX assay system 29:87 activity in iNOS assay system 29:87 Bisabolanes 23:830;26:457;27:13 highly sweet compound from 27:13 R-c~-Bisabolene 16:232 6-Bisabolene 17:609 Bisabolene 26:861 Bisabolene diterpenes 15:255-257 Bisabolene isoprenologues 15:277 Bisabolol oxide derivatives 7:218 [3-Bisabolon 20:6 1-Bisabolones 8:39-44,46,48 Bisabulene sesquiterpenes 23:164 Bisacnadinine 20:265 Bisacurol 23:830 Bisacurone 23:830 Bisacurone A 23:830
Bisacurone B 23:830 Bisanhydrobacterioruberin 20:601 Bisaryltetrahydrofurans 17:325 Bisbenzofuranoid terphenyls 29:284 as PEP inhibitors 29:284 in antimicrobial assays 29:284 Bisbenzofuranoid terphenyls 29:284 p-terphenyl benzobisbenzofurans corticin A as 29:285 m-terphenyl corticin C as 29:285 meta-terphenyl kynapcin-9 as 29:284 Bisbenzylisoquinoline 22:22;26:824, 825,826,827 Bisbenzylisoquinoline alkaloids 6:472, 657,525;25:530;30:584 berbamin 25:530 decricine 25:530 isochondroendrine 25:530 macoline 25:530 oxycanthine 25:530 rodiasine 25:530 tubacurarine 25:530 Bisbenzyltetrahydrofurans 17:330 Bisbrusatolyl esters 7:383,384 Bisbrusatolylsebacate 23:305 Bisbrusatolylsuccinate 23:305 Bisbrusatoryladipate 23:305 Biscarbamate 22:220 Bischler-Napieralski condensation 14:763 isokomarovine from 14:763 komarovidine from 14:763 of tryptamine 14:763 with quinoline-5-carboxylic acid 14:763 Bischler-Napieralski cyclization 4:20, 23,444 Bischler-Napieralski reaction 3:460, 93,633,790;8:291 Bisconicasterone 26:1177 Biscumol 23:830 Biscyanopropylhenyl siloxane 9:456 Biscyclolobin 20:283 Bisdehydroneotuberostemonine 21:770 Bisdehydrostemoninine 21:770 Bisdehydrotuberostemonine 21:770 6,10-Bisdeoxyaucubin 7:465,466,474, 476,477
117 Bisdesmosyl saponin 25:108,120
Bis-Fischer indolization 12:376,377 Bishofianin 23:406 Bishopamholide 7:234 Bishopsolicepolide 7:234 Bisindoles 29:225 arcyriacyanin A as 29:226 arcyriaflavin A as 29:225 arcyriaoxocin A as 29:226 arcyriarubin A as 29:225 structures of 29:226 Bisindole-type alkaloids 5:121,129 aceedinine 5:112 aceedinisine 5:112 biomimetic synthesis of 13:404-407 bis (11-hydroxycoronaridyl) 5:121,129 bonafousine 5:122 capuvosine 5:114 conodurine 5:116 16-decarbomethoxy- 19'20'dihydrovoacamine 5:114 16-decarbomethoxyvoacamine 5:114 14,15-dehydrotetrastachyne 12,12'-5:121 dehydroxycapuvosine 5:114 N4-demethylcapuvosine 5:114 11-demethylconoduramine 5:115 N4-demethyltabernamine 5:113 N4'-demethylvoacamine 5:115 20R- 1,2-dihydrocapuvosidine 5:114 20S- 1,2-dihydrocapuvosidine 5:114 20'S- 19',20'-dihydrotabernamine 5:114 divaricatine 5:118 ervafolene 5:120 ervafolidene 5:121 3-epi-ervafolidene 5:121 (3R)-ervafolidine 5:120 3-epi-ervafolidine 5:121 ervafoline 5:120 ervahanine A 5:115 ervahanine B 5:115 ervahanine C 5:115 gabunamine 5:115
gabunine 5:115 hazuntiphylline 5:120,121 3-R/S-hydroxy- 16-decarbomethoxy conodurine 5:115
19'S-hydroxy-3-epi-ervafolidine 5:121
3-R/S-hydroxyconoduramine 5:117
3-R/S-hydroxyconodurine 5:118 19'-hydroxyervafolene 5:120 19'-R-hydroxyervafolidine 5:121 19'-hydroxyervafoline 5:121
3'-R/S-hydroxy-N4-demethylervahanine A 5:115
3'-R/S-hydroxy-N4-demethylervahanine B 5:115
3'-R/S-hydrox y-N4-demethyltabemamine 5:114,124 19R-hydroxytabernaelegantine B 5:117
3'-R/S-hydroxytabernaelegantine B 5:117
3'-R/S-hydroxytabernamine 5:114
3'-3R/S-hydrox yvoacamine 5:117 isobonafousine 5:122 isocapuvosine 5:114 3-methoxyltabemacelegantine C 5:118 moinogagaine 5:119 3-oxo-conodurine 5:116 3-(2-oxopropyl)-conodurine 5:18 pandicine 5:118 pseudo-vobparicine 5:119 tabernaelegantinine A-D 5:175, 118,129 tetrastachyne 5:121 tetrastachynine 5:121 voacamidine 5:116 voacamine 5:116 voacamine-N4-oxide 5:119 vobtusine 5:120 Bisindolymaleimides 29:230 cell-cycle checkpoint inhibition by 29:230 cyclin-dependent kinase (CDK) inhibition by 29:230 protein kinase C inhibition by
118 29:230 rebeccamycin as 29:230 staurosporine as 29:230 topoisomerase I mediated DNA cleavage 29:230 Bisindolymaleimides 29:230 rebeccamycin as 29:230 staurosporine as 29:230 Bisiridoids 7:443 Bisisodiospyrin 20:276 Bisisoquinoline alkaloids 21:79 (-)-5,10-Bisisothiocyanakalihinol G 25:857 a, c0-Bisisothiocyanates 25:857 3,3'-Bisjuglone 20:276 Bisketene 4:349 Bismuth citrate 25:617 15,16-Bisnor- 13-acetoxylabda8(17), 11E-dien- 19-oic acid 29:101 activity in EBV bioassay system 29:101 15,16-Bisnor- 13-oxolabda-8(17)-en- 19oic acid 29:102 activity in EBV bioassay system 29:102 14,15-Bisnor-8ot-hydroxylabd-11E-en13-one 29:101 activity in EBV bioassay system 29:101 26,27-Bisnorbrassinolide 19:263-265 Bisnordihydrotoxiferine 26:1050,1051 Bisnortoxiferine 21:79 26,27-Bisnortyphasterol 19:268 2',4'-Bis-O-(2-methoxy ethoxy methyl)4-O-methyl-7,8-dihydronogarene 14:87 (+)-2',4'-Bis- O-(2-methoxy ethoxymethyl)-7,8-dihydronogarene 14:83,87 (+)-2',4'-Bis-O-(2-methoxy ethoxymethyl)-7-con-O-methylnogarol 14:88 Bisobolane skeleton 25:849 2',3'-Bisphosphoramidite 14:293 2,3'-Bisphosphorylated ribonucleoside 14:284-290 Bis-quinoline antimalarial compounds 25:346
Bis-quinolines 25:345 Bisquinolizidine alkaloid 27:264 13C-NMR of 27:264 IH-NMR of 27:264 Bis-quinolizidnie macrocycles 24:606 structures of 24:606-609 total synthesis of 24:610,611 Bis-seco-dehydrocyclopiazonic acid 28:119 Bisstrictidine 5:140,141 7,7-Bistaxodione 20:678 from Salvia montbretii 20:678 Bistetrahydrofuran 10:439,440 Bistheonellasterone 26:1176,1177 Bis-THF acetogenins 17:270 Bis-THF structures 17:258 Bis-thiazole metabolite 25:790 Bistratamide 10:243 Bistratamide D 25:903 Bistratenes A,B 10:243 Bisubstrate mimetics 24:415 Bivittoside A 7:270,271 Bivittoside A,B,C and D 1:270;15:91 Bivittoside C 28:589,590 structure of 28:590 Bixa orellana 20:721,733,59 Bixin 30:528,529 structure of 30:529 Blaberus discoidalis 9:488,489 Blaberus gigantus 22:381 Black mycelium 21:204 Black vomit 1:679,680 Blackcurrant oil 13:659 Black-sugar 27:409,410 biological activity of 27:409,410 Blasticidin 23:343;28:127 as antibiotic 28:127 Blasticidin H 4:241,243 Blasticidin S 4:242,243 absolute configuration 4:242,243 biosynthesis of 4:243 synthesis of 4:243 Blastobacter sp. 25:841 Blastocladiella emersonii 5:276 Blastocrithidia 2:298 Blastogensis 26:217 inhibitory activity on 26:217 Blastomyces dermatiditis 5:307;22:248 Blastomyces sp. 5:325,328
119 Blastomycosis 2:422;22:60 Blatella germanica 6:53;9:488,489; 27:384 Blatellastanoside 25:757,795 Blatta orientalis 9:488,489 Blechert's construction 12:195 Bledius mandibularis 4:494 Bledius spectabilis 4:494 Bleekeria vitiensis 1:125 Bleekerine 1:125,158 oxidation 1:125,158 Bleomycins 16:573;20:458;24:547,548 antiviral microbial-derived compound 24:547,548 Blepharis edulis 27:188,191,193 Blepharispenum zangubaricum 25:251 Blepharocalyxin A 23:805 Blepharocalyxin B 23:85 Blestrin 20:280 Blighia welwitschii 15:205 Block-type polysaccharides 14:248 Blood chylomicron 30:79 obesity induction 30:79 Blood coagulation 21:670;30:70 role of serine protease in 30:70 role ofthrombin in 30:70 Blood coagulation activity 21:670 Blood glucose 30:58 effect of Ganoderman lucidum 30:58 elevation of 30:58 Blood glucose regulation 24:875 as biological action 24:875 Blood glucose regulatory action 24:875-925 of Kampo medicines 24:875-926 Blood platelet-aggregation 16:373 Blood pressure activity 21:670 Blood schizontocidal activity 22:152 Blood thrombocytopenia 26:265 Blood vessel contraction 24:875-925 of Kampo medicines 24:875-926 Blood vessel relaxation 24:875-925 as biological action 24:875 of Kampo medicines 24:875-926 Blood vessels 30:410 Blood-brain-barrier (BBB) 786,800,813 Blood-high-viscosity-syndrome 30:839 treatment of 30:839
Bloom-forming cyanobacteria 26:352 Anabaena 26:352 Aphanizomenon 26:352 Cylindrospermopsis 26:352 Lyngbya 26:352 Microcystis 26:352 Nodularia 26:352 Nostoc 26:352 Oscillatoria (Planktothrix) 26:352 Umezakia 26:352 Blossom oils 25:165;27:373 Blue cheese flavour 25:129 Blue crustacyanin 30:533 Blue oxonium ions 30:531,532 formation of 30:531 via cyclic hemiketals 30:532 Blue-green algae 21:303,304,367,415 Blumea malcomii 5:678 Blumenkrantz method 25:435 Bmy-41950 12:366,368 from Streptomyces staurosporeus 12:366,368 Boariol 18:743,752 Boat-boat inversion potential 27:343 of 1,4-cyclohexadiene 27:343 Bobolstemma paniculatum 21:665,674 N-BOC (3R,4S)-statine 12:480 from (3R,4S)-statine 12:480 BOC anhydride method 12:121 BOC functionality 4:91,92 deblocking with TMSOT 4:91,92 N-BOC-l-allo-threonine methyl ester 12:430 N-BOC-2-amino alcohol 12:480 (R)-N-BOC-2-amino alcohols 12:435, 436 with thionyl chloride 12:435,436 N-Boc-3-methyl-3-pyrroline-2-one 21:418 (S)-N-BOC-amino alcohols 12:481 O-N-BOC-amino benzaldehyde 18:163 N-Boc-ampullicin 21:418 Bocconia arborea 27:163,170 Bocconia cordata 26:488 Bocconiafrutescens L. 27:163 Bocconia genus 27:162 Bocconia integrifolia 27:163 Bocconia pearcei 27:163
120
Bocconia sp. 27:155 Bocconine 26:488 Bocconoline 27:168 (3 R,4R,5S)-N-BOC-dolaisoleucine 12:486 (• oc-L-phenylalanyl 22:280 N-BOC-L-threonine methyl ester 12:430 from methyl trans (4S,5R)-5methyl 3-tert butoxycarbonyl-2oxo-oxazolidine-4-carboxylates 12:430 N-BOC-proline 19:54 N-BOC-tyrosine 16:609 photooxygenation of 16:609 Boekman-Silver synthesis 6:18 of (-)-[5-gorgonene 6:18 Boerhavia diffusa L. 22:514;26:233 as anticonvulsive agent 22:514 liriodendrin from 26:233 Boerhavia repens L. 22:514 Boesenbergia 23:819 Boesenbergia pandurata 23:819;29:775 Boesenbergin A 23:821 Boesenbergin B 23:821 Bohadschia argus 7:270 bivittoside B,C from 7:270 Bohadschia bivittata 28:589 bivittosides A, B, C and D from 15:91 Bohadschia graffei 7:269 holothurins A,B from 7:269 holothurin A2 from 7:269 Bohadschia marmorata 7:270 bivittoside B,C from 7:270 Bohadschia tenuissima 7:270 bivittoside B,C from 7:270 Bohadschia vitensis 7:270 bivittoside B,C from 7:270 Bolabella auricularia 27:804 Bolbostemma paniculatum 7:143,144; 21:639 tubeimoside I from 21:645,665 Boldine 21:52,57,96,97,102,108 Boletinus cavipes 20:26 Boletopsis grisea (Polyporus griseus) 29:277 Boletopsis leucomelaena 29:284 Boletus edulis 5:289
Bolinea lutea 22:249 Bolivianol 30:711 structure of 30:711 Boll weevil pheromone 1:693 Bombax malabaricum DC. 22:514 for epilepsy 22:514 Bombesin analog 27:797 from emphibianskin 27:797 Bombesin receptor antagonists 28:221 from Morus species 28:221 ofkuwanon G 28:221 of kuwanon H 28:221 Bombesin-induced phospholipase C activity 15:447 Bombina variegata 23.341 Bombsin 27:797 biological activity of 27:797 Bombyx mori 5:832;19:647;22:396; 23:661 ;26:991 ;29:6,10,25 Bonafousine 5:128 Bonanzin 7:226 Bone calcium mobilization 9:514; 30:484 role of vitamin D2 in 30:484 Bone marrow hypoplasia 26:688 Bone mobilization 30:497 assay for 30:497 in vivo 30.'497 Bone resorbing " ~tivity 30:495 of la,25tOH)2D2 30:495 of lct,25(OH)2D4 30:495 of la,25(OH)2D3 30:495 Bone resorption 21:702 inhibitory activity on 21:720 inhibitory effect on 21:702 Bonnet de Pretre 23:655 Boophiline 25:706 Boophilus decoloratus 28:396,400 Boophilus microplus 25:706;28:398,402 essential oils from 28:398 Boophilus sp. 28:401,402 9-Borabicyclo [3.3.1 ] nonane (9-BBN) 13:72 Borage oil 13:659 Boraginaceae 21:3,97 Borane-methyl sulfide complex 11:360 Boration 9:366-368 Bordeaux terpentine 29:83
121 Bordetella pertussis 25:521,538 Borealosides A-D 15:71 Boric acid 25:674 Borjatriol 25:249,250;29:102 activity in CTN bioassay system 29:102 Bormination 4:629,633,634,656,657 of camphor 4:629,633,634, 656,657 of camphor derivatives 4:629632,633,634,636,656-658 1-Borneol 10:52 Borneol 9:530;21:598,601;25:128,154 (+)-Borneol 27:376 structure of 27:376 Born-Oppenheimer approximation 2:155 Borntr~iger reaction 26:644 (+)-Bornyl acetate 4:645,46,648 Boromycin 5:377,414,11:207,208 Boron aldolate 30:23 in situ reduction of 30:23 Boron enolate 13:500 of 3 (R)-3-hydroxybutanethioate 13:500 Boronic ester 11:409 Borophycin 21:303,316 Borrecarpin 11:278 from Borreria capitata 11:278 Borrelia burgdorferi 21:646;26:695 Borreria capitata 11:278 borrecarpin from 11:278 Boschnialactone 8:140,155-157; 20:72,74,76;16:701 Bose reaction 4:440,441 by 3-hydroxybutyric acid 4:440,441 by ketene-imine cycloaddition 4:440 in azetidinone formation 4:440, 441 Boswellia serrata 22:126,136;29:585, 586,691 [3-Boswellic acid (triterpene) 29:585 effects on leukocyte ELA 29:585 Boswellic acids 22:110,116,120 Botanical/ecological description 27:661
Botanical juvenile hormones 18:498 Bothriochloa bladhi 11:278 eudesm- 11-en-4-ols from 14:450 (+)-intermedeol from 14:450 neointermedeol from 14:450 Bothriochloa glabra 14:450 eudesm-11-en-4-ols from 14:450 (+)-intermedeol from 14:450 neointermedeol from 14:450 Bothriochloa grasses 14:450,451 intermedeol from 14:450,451 neointermedeol from 14:450,451 Bothriochloa insculpta 14:450,451 eudesm-11-en-4-ols from 14:450 (+)-intermedeol from 14:450 neointermedeol from 14:450 Bothriochloa intermedia 14:449- 451 eudesm- 11-en-4-ols from 14:449-451 intermedeol from 14:450,451 neointermedeol from 14:450,451 Botryllamide A 23:241 Botryllamide B 23:241 Botryllamide C 23:241 Botryllamide D 23:241 Botrylus leactis 25:706 Botrylus schlosseri 25:719 Botryodiplodia malorum 25:143 Botryospheria obtusa 25:318 Botryotinia fuckeliana 12:400 Botrytis 4:246 Botrytis cinerae 5:598;21:196,213,217; 22:459,45 ;25:138,305,313,314,316, 662;26:404,405,508,553,555 ;27:768 Botrytis fabae 2:434 Botulinum 13 21:16 Botzella sp. 25:790 (-)-[3-Bourbonene 10:405,406 Boussingaultia baselloides 21:666 12,20(29)-diene- 30-noro leano lic acid from 21:666 Bouvardia ternifolia 24:306,309,319 bouvardins from 10:640 Bouvardins 10:640 from Bouvardia ternifolia 10:640 Bovine brain FPTase activity 24:446 of cylindrols 24:445-447 Bovine endothelin 25:841
122
Bovine insulin 2:45 molecular ion region 2:45 Bovine papillomavirus type 1 30:406 microbicidal compound against 30:406 Bovine serum albumin (BSA) 7:114, 115;22:374;27:330;30:837,844 F-II hydrolysis of 30:837 phytolysis of 27:330 Bowlesia 27:661 Bowman-Birk protease barley rootlet BBI 29:599 barley seed BBI as 29:599 bsil (fungus-induced) as 29:599 Coix BBI TI-1 as 29:599 dual function a-amylase/trypsin CM (chloroform-methanol soluble proteins) 29:602 OsBBPI as 29:599 RBBI-8 as 29:600 RBTI as 29:599 WIP1 variants (genes) as 29:600 WTI (BBI Type I), as 29:600 Bowman-Birk serine protease inhibitor proteins 29:598 A-I as 29:598 A-II as 29:598 B-I as 29:598 B-II as 29:598 B-III as 29:598 ATI (alfalfa trypsin inhibitor) as 29:598 BBI-1 as 29:598 BBPIP as 29:598 BTCI as 29:599 C-II as 29:598 CLTI-I as 29:598 CLTI-II as 29:598 CPTIs as 29:599 DATI as 29:598 DE-1 as 29:598 DE-2 as 29:598 DE-3 as 29:598 DE-4 as 29:598 DgTI as 29:598 D-II as 29:598 EBI as 29:598 E-I (PI-I) as 29:598 FBI as 29:599
HGI-III as 29:598 I (ABI-I) as 29:598 I-A, I-B, I-A', II, II', I I-A as 29:598 Boy6/Brossi 29:378 allocolchicinoids total synthesis by 29:378 Boyer and Hanna 29:497 carbaoxirose/carbaoxetoses synthesis by 29:497 Boyer and Lallemand 29:499 homochiral (+)-calystegines B2 synthesis by 29:499 homochiral (-)-calystegines B2 synthesis by 29:499 BPV-4 (Bovine papilloma Virus type 4) 26:761 Brabeium 26:1157 Brachyoside A 25:197 Brachyoside B 25:192 Brachyoside C 25:197 Brachyponera sennaarensis 5:224,225, 254 Bracken carcinogens 26:705 Brackenridgea zanguebarica 7:408; 23:342 Bractazonine 6:478,487,270 Bradsher cycloaddition 24:630,631 Bradycardia 30:191,194 as pain mediator 30:192 due to opioids 30:194 Bradykinin 9:296,298 from Rana nirgomaculata 9:296 from Rana temporaria 9:296 Bradykinin B2 receptor 30:203 interaction with ginseng 203 Bradykinin induced edema 25:46 inhibition of 25:46 Bradykinin receptors 21:73 Bradyrhizobium sp. 26:1154,1155 Brafouedine 9:172 Brain 30:192,383 COX 3 enzyme in 30:192 serotonin (5-HT) receptors in 30:383 Brain development 30:375 serotonin (5-HT) 5A receptor in 30:375
123
Brain enzymes 30:816 resistance to 30:816 Brain membrane synaptosomes 30:814 radioligands from 30:814 Brain neurons 30:371 Brain processes 30:367 role ofserotonin 30:367 Brain stem 30:370 tryptophan hydroxylase (TPH) in 30:370 Bramia monnieri L. 22:513 for epilepsy 22:513 8-Bramodesoxypicropodophyllin 18:593,596 Branched amino sugars 10:421 synthesis of 10:421 Branched chain nucleosides 4:254-257 synthesis of 4:254-257 Branched decarbonucleotide 14:299,302 synthesis of 14:299,302 Branched hexaribonucleotide 14:291, 292 synthesis of 14:291,292 C-Branched nucleoside analogues 19:511-547 stereoselective synthesis of 19:511-547 Branched oligoribonucleotides 14:283-303 synthesis of 14:283-303 Branched RNAs 14:293 synthesis of [A(2'-pX)pX] 14:293 synthesis of [A(2'-pY)pX] 14:293 synthesis of [A(2'-pU)pU 14:293,294 synthesis of [CpUpA(2'-pGpU) pUpC] 14:299,301 synthesis of 14:284-303 via 3'-bis(2-cyanoethoxy) phosphoryl group 14:291,292 via 2',3'-bisphosphorylated ribonucleoside unit 14:284-290 via phosphoramidite approach 14:293,294 Branched tetrasaccharide 10:476,477 synthesis of 10:476,477
Branched triribonucleotide 14:294,295 synthesis of [A(2'-pA)pA] 14:294,295 synthesis of [A(2'-pG)pC] 14:289,290,297-299 synthesis of [A(2'-pG)pU] 14:290,298-300 synthesis of [A(pG)pC] 14:289,290 synthesis of [araA(2'-pU)pU] 14:294 synthesis of [GpA(2'-pG)pC] 14:295-297 synthesis of [pA(2'-pA)pA] 14:294,295 synthesis of [pppA(2'-pA)pA] 14:294,295 synthesis of [U(2'-pA)pU] 14:296,297 Branched trisaccharide 10:476,477 synthesis of 10:476,477 Branch-point specificity 7:32,33 of glycohydrolase 7:32,33 Brasilane sesquiterpene 18:633 from Laurencia implicata 18:633 from Laurencia obtusa 18:625 epi-Brasilenol 6:6 from Aplysia brasiliana 6:6 from Laurencia obtusa 6:6 synthesis of 6:6,7 (+)-Brasilenol 6:7,8 stereoselective reduction of 6:7,8 Brasilenol 6:8 by o~-dimethylation 6:8 by Wacker oxidation 6:6 from Aplysia brasiliana 6:6,249 from brasilenone 6:7,8 fromLaurencia obtusa 6:6 synthesis of 6:6,7,625 Brasilenol acetate 6:8 from Aplysia brasiliana 6:6 from Laurencia obtusa 6:6 synthesis of 6:6,7 Brasilenone 6:7,8 Brasiliensoside 15:55 Brassica (SRK) 25:368,386 Brassica BN 29:618
124
Brassica compestris L. 19:246;26:187, 481 Brassicajuncea 24:57,60 Brassica napus L. 18:495,498;19:245; 25:413 ;27:217;29:603,612,618 Brassica nigra L. 22:514;29:618 for epilepsy 22:514 Brassica oleraceae 26:748;29:603,612 Brassica rapa 28:425 Brassica sp. 23:756 Brassica TIBN 29:618 Brassicasterol 16:324 from canola oil 16:324 Brassin 25:413 Brassino steroid precursors 25:415 Brassinolide 16:321 antiecdysteroid activity of 16:321 biological activity of 19:245,281 chemical structure of 19:245 from Brassica napus 18:495 isolation of 19:245 plant growth promoters 16:321; 19:245 structure-activity relationship of 19:281 Brassinolide 25:415-416 Brassinone 18:500 Brassinosteroid 25:316,413,420,425, 367 Brassinosteroid biosynthesis 18:520 Brassinosteroid intermediates 25:414, 417 Brassinosteroid metabolites 18:534-546 Brassinosteroid pathway 25:421 Brassinosteroids 19:245-287,473 antiecdysteroid activity of 16:321 application of 19:242-287 biological activity of 19:473 biosynthesis of 19:283 construction of side chain of 19:245-287 from Brassica napus 19:473 isolation of 19:473 metabolism of 18:520-533 stereoselective synthesis of 16:321-364
structure novelty of 19:473 synthesis of 19:245-287 Brassinosterol pathway 25:426 Braun homogenizer 19:692 Braxins A1 26:704 Braxins A2 26:704 Brazilin 20:777,780 Brchtold et al. 29:200,203 triptolide synthesis by 29:200, 203 Breast cancer 24:933 Bredereck's reagent 8:262,316 Bredius mandebularis 1:684 Bredius spectabilis 1:684 Bredt's rule 12:72 Brefeldin 26:452 Brefeldin A 8:140,149;27:871 Brein 29:586;30:206 effects on CHY 29:586 use in inflammatory skin conditions 30:206 Brein 3-O-myristate (urs- 12-ene3~,16~-diol 3-O-myristate) (triterpene) 29:586 effects on CHY 29:586 Brein 3-O-palmitate (urs- 12-ene3~, 16~-diol 3-O-palmitate) (triterpene) 29:586 effects on CHY 29:586 Brenania sp. 21:125 Brenzcatechin 15:328 Brettanomyces anomalus 5:283 Brettanomyces bruxellensis 5:283 Brettanomyces dublinensis 5:283 Brettanomycesmyces lambicus 5:283 Brevetoxin 25:730,864 Brevetoxin A 10:208 Brevetoxin B 10:201,203-205 Brevetoxin B1 25:864 Brevetoxin B2 25:864 Brevetoxin B4 28:656 as toxin 28:656 from Perna canaliculus 28:656 in shellfish poisoning 28:656 Brevetoxins 21:300,301 (+)-Brevianamides A and B 17:475 Brevibacterium ammoniagenes 20:32 Brevibacterium divaricatum 6:385
125
exo-Brevicomin 1:637,'11:413 enantioselective synthesis of 1:637 from Dendrocotonus brevicomis 11:413 synthesis of 11:413,414 Brevicomins 13:328 Brevicoryne brassicae 23:66 Brevifoliol 20:100 Brevilin A 26:809 Brewer's wort 25:139 Briareum excavatum 25:670 Brickellia lemmonic 25:230 Brickellia veronicaefolia 5:680 Brickellin 5:673-677 2,6-Bridged 3-benzazocines 6:471 in benzomorphans 6:471 Bridged bicyclo [4.2.2] ring system 12:65 Bridged C-disaccharides 10:367 from (x-methylene lactones 10:367 Bridged systems 6:65-87 Brine shrimp 9:385,387-400;24:864,865 bioassay of 24:864,865 lethality bioassay of 9:385, 387-400 Brine shrimp bioassay 30:733 Brine shrimp toxicity 9:395;24:944-950 of endophytic fungi 24:944-950 of Goniothalamus giganteus 9:395 Bripiodionen 28:117,118 as human cytomegalovirus protease inhibitors 28:118 cytotoxicity of 28:118 Broad spectrum activity 28:332 of anthelmintics 28:332 Brochamin 26:745 Bromelain 30:840 Brominated aminoimidazolinylindole 25:763 Brominated compounds 17:9 amides 17:84 diphenylether 17:9 phenols 17:81 phenylether 17:9 Brominated indole alkaloids 25:712 Brominated phenylethylamine 25:765
Brominated terpenoids 6:24,56 Bromination 14:269 3-bromo-levoglucosenone 14:269 chemoselective 19:314 Bromination-dehydrobromination sequence 12:237 Brominative cyclization 6:24 in brominated terpenoids 6:24 in glanduliferol synthesis 6:63,64 of ( 8R/S,9R/S)-8-brome-9hydroxy-(E)-bisabolene 6:62,63 Brominative rearrangement 4:474 4-Bromo-azetidinone 4:474 Bromine addition 16:336 Bromlactonisation 8:301 ofbromolactone 8:301 of (4S)-3-methylmuconolactone 8:300,301 5-Bromo- 1,2-dihydroacronycine 20:789 3-Bromo-2,5-dimethyloxyanitine 21:442 6-Bromo-2-1ithio-6-methyl-2-phenyl heptane 8:6,7 2-Bromo-3,3-diethoxy-l-propene 2:36 1-Bromo-3E, 5E-decadienoyl bromide 23:191 9-Bromo-3-endo-methyl camphor 4:630,631 acid catalysed rearrangement 4:630,631 reactivity towards bromination 4:629 3-endo-Bromo-3-exo-methyl camphor 4:657,658 2-Bromo-3-hydroxybutyric acid 4:473-475 (R)-l-Bromo-3-methylnonanol 26:66 trans-5-Bromo-4-methoxy derivatives 12:419-421 as 2-amino alcohol synthon 12:418-421 diastereselectivity of 12:419-421 from 3-acyl-2-oxazolone 12:418, 419 from 3(1S)-ketopinyl-2oxazolone 12:419-421 4-Bromo-5-ethoxysampangine 23:6
126
6-Bromo-5-hydroxy indole 25:792 6-(p-Hydroxyphenyl)-2H-3,4dihydro- 1,1,-dioxo-l,4-thiazine 25:862 7-B romo-6,8-dihydro xy-3-propyl-3,4dihydro-isocoumarin 15:386 9-Bromo-6-endo-methylisofenchone 4:630,631,635 synthesis of 4:630,631
(8R/S,9R/S-8-Bromo-9-hydroxy-(E)- T-
bisa bolene 6:62,63 3'-Bromo-ABA 27:353 (E)-[3-Bromoacrylamides 21:382 [3-Bromoacrylates 8:141 (E)-3-Bromoacrylates 8:150,151 synthesis of 8:150,151 Bromoagelifterin 25:779,780 7-p-Bromoanilino-7-demethoxy mitomycin 13:434 X-ray crystal structure of 13:434 Bromoapotrichothecene 6:2342Bromobenzene 25:460 11-Bromobenzoate 7:389 of 11-hydroxycanthin-6-one 7:389 X-ray analysis of 7:389 p-Bromobenzoyl derivative 25:816 N-(p-Bromobenzoyl) palytoxin 5:391,393 4-Bromobenzyltryptamine 26:125 Bromoboronylether 30:214,215 boron tribromide from 30:214 conversion of 30:215 (+)-9-Bromocamphor 16:128 9-Bromocamphor 16:133 (+)-5-Bromocamphor 16:144 (-)-6-Bromocamphor 16:148 (+)- 10-Bromocamphor 4:628,629 from (+)-3,3-dibromocamphor 4:628,629 (+)-endo-3-Bromocamphor 4:628,633, 634 acid catalyzed rearrangement of 4:635,643 bromination of 4:656,657 sulphonation of 4:628,633,634 (+)-9-Bromocamphor 4:633-635,657, 658
8-Bromocamphor 4:640,641;16:135 synthesis of 4:640,641;16:135 (+)-endo-6-Bromocamphor 4:644 from (+)-cx-pinene 4:644 (+)-exo-5-Bromocamphor 4:646 synthesis of 4:646 (+)-3-Bromocamphor- 8-sulfonic acid salt 12:279 Bromocarbenoid procedure 1:263 Bromocarbenoid ring expansion 1:263 Bromochamigrene 6:60,61 by spiroannulation 6:60,61 by Wittig reaction 6:61 from cyclohexanone aldehyde 6:61 from Laurencia majuscula 6:60 from phenolic c~-diazoketone 6:60,61 synthesis of 6:60-62 (Z)-3-Bromo-cinnamate 20:789 Bromoconduritol B epoxide 7:38,39 with [~-glucosidase 7:38,39 Bromoconduritol F 7:38,39 with [3-glucosidase 7:38,39 Bromocontryphan 21:320,321 T-Bromocrotonate 21:383 Bromocryptine 13:658 2-Bromocyclohexanone 12:247 cx-Bromocyclohexenones 4:18,19 hydroindolenones from 4:18,19 2-Bromocyclopentenone 10:48 Bromodecanal 26:83 wittig reaction of 26:83-91 8-Bromodesoxypodophyllotoxin 18:593,595 1-cx-Bromo-desoxypodophyllotoxin 18:598 1-[3-Bromo-desoxypodophyllotoxin 18:598 T-Bromodienamide 21:400 Bromodilactone 8:301 absolute configuration 8:301 X-ray analysis of 8:301 relative configuration of 8:301 2-(2-Bromoethyl)- 1,3-dioxolane 26:80 7-Bromo-eudistomidin D 23:266 Bromohydrin formation 1:523 3-Bromohymenialdisine 21:270
127 6-Bromoindole-3-aldelyde 23:257 Bromolactonization 3:265,336-339,177 3-Bromo-levoglucosenone 14:269 from levoglucosenone 14:269 Bromomesylate 19:229 c~-(Bromomethyl)acrylate 30:470 condensation with 30:470 Bromomethylethoxylate 30:443 4-Bromomethylphenyl 2,3,4,6-tetra-Oacetyl-ot-D-galacto-pyranoside 21:165 4-Bromomethylsampangine 23:6 6-Bromo-Nb-methyl-Nbformyltryptamine 18:691,726 18-Bromo-octadeca- 15,17-diene- 15ynoicacid 25:802 Bromoperoxidase 19:454 Bromophakellin 21:270 o-Bromophenacyl okadaate 5:389 2'-Bromophenoxy ether 21:284 p-Bromophenylboronate derivative 8:19 2'-Bromopodophyllotoxin 18:576 Bromopuupehenone 15:299 2-Bromopyridine 6:312 2-pyridine carboxaldehyde from 6:312 Bromopyrrole alkaloids 25:762 5-Bromopyrrole-2-carbamide 25:780 Bromopyrroles 25:711,712,779,784 Bromorebeccamycin 12:366,368 from Saccharothrix aerocolonigenes 12:366,368 3-Bromosampangine 23:6 4-Bromosampangine 23:6 N-Bromosuccinimide 21:162 (-)-Bromothebaine 18:87 2-Bromothiazole 30:443 Bromotyrosin derivative 25:766 3-Bromotyrosine 21:307 Bromotyrosine 23:241;25:642 derivatives 25:766 Bromotyrosine alkaloids 25:712 Bromoxynil 26:374 o~-Bromo-o~-arylacetic acid 6:321 synthesis of 6:321 10-Bromo-ot-chamigrene 6:60 from geranyl acetone 6:60
from Laurencia species 6:60 synthesis of 6:60 (+)-2-Bromo- [3-chamigrene 6:63 from Laurencia pacifica 6:63 Bronchitis 30:58,88 Ganoderman lucidum in treatment of 30:58 Platycodon grandiflorum in treatment of 30:88 Bronchodilators 5:759 in treatment of asthma 5:759 Broncholytic activities 21:633 Brook-Rubottom-Hassner oxidation 12:25,26 ofenol silane 12:25,26 Brosimone A 28:201 from moraceous plants 28:201 Brosimone D 28:201 from moraceous plants 28:201 Brosimones 17:456 Brosimopsis oblongifolia 28:203 Broussoaurone A 28:16,17 antioxidant activity of 28:16,17 as cyclooxygenase inhibitor 28:16,17 as neutrophils respiratory burst inhibitor 28:16 as nitric oxide production inhibitor 28:16 as platelet aggregation inhibitor 28:16,17 Broussochalcone B 28:228 biological activity of 28:228 Broussoflavan A 28:16 antioxidant activity of 28:16 as platelet aggregation inhibitor 28:16 Broussoflavonol B 28:226,229 anti-human immunodeficiency virus (HIV) activity of 28:226 biological activity of 28:229 Broussoflavonol C 28:226,229 anti-human immunodeficiency virus (HIV) activity of 28:226 biological activity of 28:229 Broussoflavonol E 28:17,230 as platelet aggregation inhibitor 28:17 biological activity of 28:229
128
Broussoflavonol F 28:17 antioxidant activity of 28:17 antiproliferative activity of 28:17 as aromatase inhibitor 28:17 as cyclooxygenase inhibitor 28:17 as platelet aggregation inhibitor 28:17 Broussoflavonol G 28:17 antifungal activity of 28:4 antiinflammatory activity of 28:4 antioxidant activity of 28:4,17 antiproliferative activity of 28:17 antispasmodic activity of 28:4 sexual potency of 28:4 Broussonetia genus 28:3 Broussonetia kazinoki 28:3-5 antifungal activity of 28:4 antiinflammatory activity of 28:4 antioxidant activity of 28:4 antispasmodic activity of 28:4 broussonetine C from 28:5 broussonetine D from 28:5 broussonetine E from 28:5 broussonetine F from 28:5 broussonetine G from 28:5 broussonetine H from 28:5 broussonetine K from 28:5 broussonetine L from 28:5 broussonetine M from 28:5 broussonetine N from 28:5 broussonetine O from 28:5 broussonetine P from 28:5 broussonetine Q from 28:5 broussonetinine A from 28:5 broussonetinine B from 28:5 broussonol A from 28:6 broussonol B from 28:6 broussonol C from 28:6 broussonol D from 28:6 7,4'-dihydroxyflavan from 28:6 for increased vision 28:4 kazinol A from 28:6 kazinol D from 28:5 kazinol E from 28:6 kazinol K from 28:5 kazinol Q from 28:6 kazinol R from 28:6 sexual potency of 28:4
Broussonetia papyrifera 27:834;28:3,4, 16,22;29:793 anti-cancer activity of 28:4 antifungal activity of 28:4 antioxidant activity of 28:4 diaphoretic activity of 28:4 in dyspepsia 28:4 in pregnancy 28:4 laxative activity of 28:4 Broussonetia zeylanica 28:3,4,28 aromatase inhibitory substance from 28:4 broussonetine from 28:28 cytotoxic flavonoids from 28:4 3,4 '- dihydroxy-2,3 '-b ip yridine from 28:28 8-hydroxyquinoline-4carbaldehyde from 28:28 8-hydroxyquino line-4carbaldehyde oxime from 28:28 glycosidase inhibitory alkaloids from 28:4 Broussonetine 2:242,244-246;5:752 Broussonin A 28:16 antifungal activity of 28:16 as aromatase inhibitor 28:16 Broussonin B 28:16 antifungal activity of 28:16 Brown and Robin 29:392 steganes synthesis by 29:392 Brown's crotylboration 18:280 Brownioside 15:191 Broxil 17:616 Bruccantin 5:39-41 Brucea antidysenterica 23:285 quassinoids from 7:374-376 Bruceajavanica 23:292;26:211 bruceoside-A from 7:371 bruceoside-B from 7:377 guaiacylglycerol-~-O-6'-(2methoxy) cinnamyl alcohol from 26:211 quassinoids from 7:377-379 Brucea sumatorana 7:391 Bruceanol-C 23:313 Bruceanol-G 23:289,313 Bruceanol-H 23:313 Bruceantarin 7:374;23:285
129 Bruceantin 7:369-374,383,386-388, 391,392,396,398,71-73,79-95,654, 657;23:285,313 Bruceantin-4,5-epoxide 7:388 Bruceantin-5'-ol 7:388 Bruceantinol 7:374,375,392 4,5-Bruceantinolefin 7:388 Bruceantinoside A-C 7:375-377 Bruceantinoside-A 23:313 Bruceantinoside-B 23:313 Bruceantinoside-C 23:288,313 Brucein A 7:378,392,394-396 Brucein B 7:392,395,396;23:304 Brucein C 7:375,388,394,396;23:304 Brucein D 7:377,391,392,397;23:312 Brucein E 23:312 Bruceolide 7:371,391,392,392 15-[(E)-non-Z-enoyl]-Bruceolide 7:395 Bruceoside-A 7:371 from Bruceajavanica 7:371 Bruceoside-B 7:377;23:312 from Bruceajavanica 7:377 Bruceoside-C 23:312 Brucine 9:189;26:1030,1049 Brucine N-oxide 26:1049 Brugierol 7:193,194 Brugine 7:191,192 Bruguiera conjugata 7:193,194 Bruguiera cylindrica 7:176,193,194 Bruguiera exaristata 7:191 Bruguiera gymorhiza 7:176,180-182, 188,195 Bruguiera parviflora 7:180,195 Bruguiera sexangula 7:176,191 Bruguiera sp. 7:176 Brusatol 7:79,377,383,387,392,394,397, 11:80;26:815,816 Brusatolyl ester 7:377,383 Bryonia alba 20:13 Bryonia dioica 15:24;20:13;22:121; 27:14,25;29:614 bryoclulcoside from 27:14 bryonoside from 27:14 bryoside from 27:14 Bryonolic acid-3-succinatel 22:121 Bryonoside 15:24;27:14,25,26 from Bryonia dioica 15:24 structure of 27:26 Bryophyta 27:735
Bryophytes 2:277;20:468;26:185 sesquiterpenes of 20:468 Bryoside 15:24;27:14,25,26 from Bryonia dioica 15:24 structure of 27:26 Bryostatin 19:572;25:684,726,726; 27:832 as anticancer drugs 19:550,572 derivatives 25:727 pharmacological aspects of 19:572 Bryostatin A and B 18:716 Bryozoa 21:3,316 Bryozoan 17:74;21:360;25:825 ;28:618 as moss animal 28:618 lophophore of 28:619 sulfur-containing 28:618 taxonomy of 17:74 U-shaped gut of 28:619 zooids of 28:619 Bryum argenteum 2:277 BSA (Bovine serum albumin) 7:114, 115 Bt2 cAMP 25:489,496 Bt2 cAMP-treated carrot cells 25:490 Btg C 21:751
Buchenavia capitata 21:132 Buchenavianines 21:132 Biichi and Powell 29:472 carbaaldopyranoses synthesis by 29:472 Buchnera cruciata 22:514 Buddleja davaidii 20:644 buddlenol A from 20:644 Buddleja globosa 29:686 Buddleja madagascariensis 21:660 Buddlejasaponin 27:672,677,688 Buddlenol A 20:644 from Buddleja davidii 20:644 Buddleyasaponin IV 21:656 Budleyasaponin 21:674 Budmunchiamines 22:28 Bufadienolide 25:535 Bufadienolide Scillaren A 25:535 Bufo regularis 2:310,804;26:689 Bufobufo gargarizans 24:904-905 sterols from 24:904-905 Bufogenins 15:328 Bufonidae 21:89
130 Bufonis 24:904 inhibition of capillary permeability by 24:905 Bufotenidin 15:328 Bufotenine 15:328;21:68;25:531 Bugula dentata 17:88 Bugula neritina 5:394,395,153,75,77, 89,92,18:573-574,576,715,716; 21:252,316,317;25:726 bryostatin from 21:252 Bugula trubinata 17:102 Bugula turrita 17:80 Bugularia dissimilis 17:95,101 "Built-in auxiliary" 14:552 (+)-Bulbocapine 16:509 Bulbocapnine 21:733 Bulgarane 15:247 Bulgaria inquinans 26:450 Bulgarian rose oil 25:132 Bulgecinine 14:193 (-)-Bulgecinine 16:706-707 Bulimia 30:369 effect of circadian activity on 369 Bulinus 7:426,432 Bulinus globosus 7:432,434 Bullatacin 9:396-398,252,266,271-272 Bullatacinone 9:396-398,266,278 Bullatalicin 9:397,398 Bullera sp. 5:291 Bulleyanin 15:119,126,133,171 Bulnesol 1:545 (d/)-Bulnesol 10:310,311 (+)-Bulnesol 14:364,365 Bungarotoxins 18:698 c~-Bungrarotoxin 21:52 Buntanin 13:350 from Citrus grandis 13:350 Buntenolides 24:521,522 as antiviral compound 24:521, 522 Bunya virus infection 30:410,411 mouse model for 30:411 treatment of 30:411 Bupalus piniarius 4:566 Buparvaquone 26:804 Buphanisine 4:14-17 asymmetric synthesis of 4:14,15 from Amaryllidaceae 4:3,4 synthesis of 4:13-17
Buplerom falcium 24:146,148
Bupleuroside III,IV,XIII 25:474 hepatoprotective activity of 25:474 Bupleurum bourgeaei spp. 27:662 Bupleurum chinense 27:660 Bupleurum falcatum 21:665,688; 25:474;27:660 saikosaponin from 21:665 Bupleurum fruticosum 17:117,127; 21:656; 27:693 Bupleurum genus 27:687 Bupleurum gibraltaricum 27:660,661 Bupleurum kaoi 27:660,693 Bupleurum marginatum 27:660 Bupleurum radix 21:651 ;25:474 saikosponins from 21:651 Bupleurum rigidum 27:659,662,663665,669,675,678,693 bioactive components of 27:659 biological activity of 27:688,693 roots of 27:665 Bupleurum rotundifolium 27:672 Bupleurum salicifolium 26:229 Bupleurum scorzonerifolium 25:474, 476;27:660,675 triterpene glycosides of 25:474 Bupleurum sp. 21:671,686 from roots 27:686 saikosaponins from 21:671 Bupremorphine (18,19-dehydrobupremorphine) 30:198 dehydroderivative of 30:198 derivative of 30:198 structure of 30:198 Burasaia madagascariensis 26:1038 Burchellin 8:160 synthesis of 8:160 Burgess reagent 1:16,50,53,232,257, 296,601 ;24:178,179 Burkholderia 26:582,605 Burkholderia caryophylli 26:594,599, 601,602,605 Burkholderia cepacia 26:605 Burkitt's lymphoma 26:926 Burning bush 23:655 Bursaphelenchus lignicolus 12:398; 26:429,435,493 Bursaphelenchus xylophylus 26:436,
131 442,466,470,471,474,485,487 Bursaphelocide A&B 26:485 Bursehernin 18:554,556;26:192,229; 30:568,592 as EBV inhibitor 30:592 Bursen 26:191 Bursera ariensis 17:317 Bursera microphylla 17:330 Bursera permollis 26:216-219 cholchicine from 26:216 4 '- de metho xy- 3 ',4 '-methylenedioxy-methyl rocaglate from 26:218 deoxypodophyllotoxin from 26:216 1-oxo-4 '-demethoxy- 3 ',4 'methyl-enedioxyrocaglaol from 26:218 4'-episteganangin from 26:216 (-)-deoxypodophyllotoxin from 26:218 1-O-formyl-4'-methylenedioxymethyl-rocaglaol from 26:218 methyl rocagalate from 26:218 obavatifol from 26:219 obovaten from 26:219 obovatinal from 26:219 [3-peltatin methyl ether from 26:216 perseal A from 26:219 perseal B from 26:219 perseal C from 26:219 perseal D from 26:219 steganangin from 26:216 stegancin from 26:216 steganoate B from 26:216 steganolide A from 26:216 (-)-yatein from 26:218 Bursera schlechtendalii 18:556 Burseraceae 18:558;17:370 Burseran 17:330 trans-Burseran 24:747,748 Bush beans 9:393 (Z)-But-2-ene- 1,4 diol 6:116 1-But-3-enyl-5-hydroxy-5-methylpyrroldin-2-one 12:289 with trans-7-fromyloxy-8amethylindolizidine 12:289
Butadiene 11:341 trans- cyclohexenecarboxylic acid from 11:340,341 (S)-Butan-l,2,4-triol 6:287,289 from (S)-malic acid ester 6:287, 289 Butanal 9:338,339 Butane-l,2,4-triol-l,2-acetonide 21:739 (2R,3R)-2,3-Butanediol 1:639 (2R,3 R)-2,3-Butanediol 14:471 benzaldehyde acetal from 14:477 olefinic dioxolane acetal from 14:471 (R, R)-2,3-Butanediol [(IS)- 1-chloroalkyl] boronates 11:412 (2R,3R)-2,3-Butanediol acetals/ketals 1:591,593 (R,R)-2,3-Butanediol esters 11:412 Butanolides 6:295-297 4- 0-Butanoyl-4'-demethyl podophyllotoxin 24:740,741 4- 0-Butanoyl-4'-demethyl podophyllotoxin 24:740,741 cytotoxicity of 24:740 19'-Butanoylfucoxanthine 6:134,135, 138-141 Butea frondosa 26:457 Butea monosperma (Lam.) 22:514 for epilepsy 22:514 Butein 25:546;29:572 effects on HIV- 1 protease 29:572 Butenolide 23:685 Butenylation 12:458 (E)-2-Butenyldiisopinocampheylborane 13:135 3-Butenylmagnesium bromide 12:29,30 (S)-trans-T-Butenynyl (GABA) 14:473 synthesis of 14:473 N-tert-Butoxycarbonylation 12:478,479 N-tert-Butoxycarbonyl-L-alanyl-Disoglutamine benzyl ester 6:409,410 N- tert-Buto xyc arb onyl-L- alanyl- Disoglutamine methyl ester 6:410 t-Butyl acetate 11:127,129 Claisen condensation of 11:127,129 with naphthalene glutarate 11:127,129
132
t-Butyl anthraqumone 17:561 170-NMR spectrum of 17:561 t-Butyl carbamate 23:190 tert-Butyl ester 6:413-415 of disaccharide dipeptides 6:413-415 t-Butyl hydroperoxide 12:323 tert-Butyl hypochlorite 1:451 addition to olefins 1:451 cyclization with 1:11,12 tert-Butyl tin hydride 1:443,444,451 reduction of chlorides 1:443,444, 451 reduction of dithiocarbonate 1:452,453 cis-5-Butyl-2-heptylpyrrolidine 6:438, 439 from glutamic acid 6:438 synthesis of 6:438,439
trans-5-Butyl-2-heptylp yrrolidine
6:438,439 from glutamic acid 6:438,439 synthesis of 6:438,439 (2S,5 R)-cis-5 -Butyl-2-heptylpyrro lidine 6:438-349 from pyroglutamic acid 6:438-349 synthesis of 6:438-440 3-n-Butyl-4,5-dihydrophthalide 22:537, 512 t-Butyl-5-chloro-3-oxopentanoate 8:268 3-Butyl-5-methyloctahydroindolizidine 6:445,447 as (monomorine I) 6:445,447 from 2,6-1utidine 6:445,447 synthesis of 6:445 2-Butylamino-tetrahydro [3-carboline 14:759 N-t-Butylamodiaquine 25:344 4-tert-Butylcatechol 14:617 Butylcholinesterase 21:748 N-Butyldeox-noj irimycin 10:528 2-tert-Butyldihydroxyoxazole 12:411, 413 2-amino alcohol by 12:411,413 electrophilic addition to 12:411, 413 tert-Butyldimethyl silyl ether 6:264, 268;11:339;12:282
tert-Butyldimethylsilyl (TBDMS) group 4:299,304
tert-Butyldimethylsilyl ketene acetal 1:465
tert-Butyldimethylsilylation 6:119,120 8-O-t-Butyldimethylsilyldehydrononactate 18:242
tert-Butyldimethylsilyldehydropodophyllotoxin 18:565 (+)-8-O-tert-Butyldimethylsilylnonactate 18:242
tert-B utyl dime thyls ilylp icropodop h yl lin 18:564
tert-Butyldimethylsilylpodophyllotoxin 18:563 t-Butyldiphenylsilyl ethers (TBDPS) 24:9-11 tert-Butyldiphenylsilyl trifluoromethanesulfonate 1:707,708 N-I-Butyl diphenylsilyl-S-benzyl-Smethyl sulfoximine 10:686-688 t-Butylformamidines 6:430,431 tert-Butylformamidines 6:430,431 Butylidenephthalide 24:890-892 alleviation of cardiovascularinflammation 24:890-892 inhibitory effect on SMCs 24:890-892 (t-Butylimino)-2- [(diethylamino) ]- 1,3dimethylperhydro- 1,3,2-diazaphosphorine 12:3422 2-(t-Butylimino)-2-[(diethylamino)]-l,3dimethylperhydro- 1,3,2-diazaphosphorine 12:342
t-Butyl-N-chloro-N-argentocarbamate
12:219 3-n-Butylphthalide 22:537,512 N-Butylscopolamine 22:728,735 Butyrine 21:297 Butyrolactone II 30:220 structure of 30:220 Butyrolactones 3:252-225 y-Butyrolactone 16:687-726 Butyrospermol 9:288,289,301 n-Butyryl CoA 11:197 in Streptomyces cinnamonensis 11:197 interconversion of 11:197 stereochemical 11:197
133 6-O-Butyrylcastanospermine 12:332 Butyryl-CoA dehydrogenase 20:835 (+)-Buxabenzamidienine 2:185,186, 204,205 (+)-Buxabenzamidine 2:192 structure of 2:192 Buxaceae 21:3 Buxamine- A 2:205 Buxamine - C 2:205 Buxaminol- B 2:205 Buxaminol- E 2:205 (+)-Buxaminol- G 2:183,184 (+)-Buxaminone 2:201,202,204 (+)-Buxanaldinine 2:188,2:189 (-)-Buxanoldine 2:187,204 (-)-Buxapapinolamine 2:190191 (+)-Buxaprogestine 2:199 (+)-Buxaquamarine 2:178,2:179,205 Buxatine 2:205 Buxenine - G 2:205 Buxenone 2:207 Buxocyclamine - A 2:207 (+)-Buxupapine 2:189,205 Buxus alkaloids 2:175,205 Buxus papilosa 2:175 Byakangelicin 23:351,357 Byrsocarpus coccineus 26:69 Byrsonima crassifolia 24:779,826-835 pharmacological activity of 24:828 phytochemicals of 24:828-830 uses of 24:827,828 BZSAM 23:21,44 ~H-NMR assignments of 23:44 BZSAMM 1 23:43 ~H-NMR assignments of 23:44 structure elucidation of 23:43 ~H and ~3C spectra 26:8,9,22,30,33 of aglycone of dianchinenoside G & H 26:36 ofbisdesmoside 26:41 ofdianchinenoside E 26:33,34 ofdianchinenoside F 26:37 of dianchinenoside G and H 26:35 of SAPO 30 26:41 of SAPO 50 26:41
ofsaponarioside A 26:22 ofvaccaroside F 26:30 13C NMR 30:584,586 of (7R,8S,7'R,8'R)-(+)-7'-acetyl5 '-methoxypicropodophyllin 30:586 ofherveline A 30:583 13C NMR data 23:31,195,509,599; 26:321,324,326,329;1052 13C-NMR assignments of 23:31 ~H-NMR assignments of 23:29 for monoindoles 26:1052 of hydroxyframoside A&B 26:326 ofhydroxyomoside 26:321 ofinsularoside 26:321 of isolugrandoside 26:329 of isolugrandoside acetate 26:329 13C-NMR spectra 23:111 of [3-glucans 23:111 of glucan 23:123 of lentinan 23:122 13C-NMR spectral studies 23:55 of rifamycins 23:55 13C-NMR spectrum 21:731,732,733 ~3C-NMR-spectroscopy 23:64 of streptovaricin D 23:64 13-demethyldysidenin from 28:666 13-demethyldysidenin from 28:666 13-demethylisodysidenin from 28:666 C-14 reductase 25:304 C2-P bond analogs 6:357,358 of D-erythritol 6:357,358 of D-fructofuranose 6:357,358 of D-glucopyranoside 6:357,358 of D-ribohexitol 6:357,358 C3-P bond analogs 6:359,360 of D-allofuranose 6:359 of D-altropyranoside 6:359,360 of D-glucofuranose 6:359,360 of D,L-glyceraldehyde 6:359 of D-xylofuranose 6:359 C4-Oxo group 27:924 of catechins 27:924 C40-Carotenoids 6:110,135,136,143,144
134
C4-alkylations 12:159-172 of D-lactams 12:159-172 with ester enolates 12:163,164 with imide enolates 12:164-168 with other nucleophiles 12:170-172 with thiolester enolates 12:168-170 C-4-O-acetyl derivative 28:117 C4-P bond analogs 6:360,363,364 of D-erythropentose 6:360,363, 364 of D, L-glycero-pentopyranose 6:360,361 of D-talopyranose 6:360 of L-talopranoside 6:360 Cs-P bond analogs 6:365,366 of D-erythropentofuranose 6:365,366 of D-ribofurnose 6:365,366,368 of D-xylofuranose 6:365-367, 375 of D-xylo-hexofuranose 6:365, 366,372 C6 oxidation 25:415,424 of 6-deoxocastasterone 25:415, 424 C6-P bond analogs 6:376 of D-arabino-hexo furanose 6:376 of D-erythro-hexofuranose 6:376 of D-galactopyranose 6:376 of D-glucofuranose 6:376 of D-glucopyranose 6:376 of D-ribo-hexofuranoside 6:376 of D-ribo-hexofuranose 6:376 m-CvN unit 23.79,89 C8-Hexanoate 30:27 C8-hexanoate pironetin 30:27 mitogen responses to 30:27 structure of 30:27 suppressive effects of 30:27 Cs-polyketide 12:290 Ca+* Current 22:508 Ca 2§ channels 25:531;30:194 blockade of 30:194 Ca2*/Calmodulin 25:261 Ca2+/CAM-dependent protein kinases 25:489
Ca2+-ATPase 25:492,493,524,536 Ca2+-ATPase inhibitor 25:536 xanthone a-mangostin as 25:531,536 Ca2+-calmodulin (CAM-dependent protein kinase) 25:261,524 CaZ+-Calmodulin complex 26:920 Ca2+-Cam-activated adenylyl cyclase 25:538 Ca-2+CaM-dependent protein kinase 25:522,544,546,547 CaZ+-channel agonists 28:695 Ianthella basta as 28:695 CaZ+-channel blockers 25:489 CaZ+-channels 25:521 CaZ+-dependent CAM 25:491,540 CaZ+-dependent enzymes 25:517 CaZ+-dependent K + channel 25:534 Ca2+-dependent process 25:487 CaZ+-induced LDL oxidation 25:946 CaZ+-inhibitors 25:487 CaZ+-ionophore A23189 25:487,490, 509 Ca2+-mediated signalling 25:526 CaZ+-mediated signalling targets 25:542 Ca2+-permeable ion channel 25:397 CaZ+-pumping ATPase 25:492 Ca2+-translocating ATPase 25:492 activity of 25:492,496 CaZ+-transporting systems 25:492 Caax peptidomimetics 24:413,414 structure of 24:413 Cabreuva oil 17:609;25:162 Cacachila 22:559 Cacaliahastata 19:149 Cacospongia 6:11 Cacospongia linteiformis 25:698 Cacospongiolide B 25:697 Cactaceae 21:3 5'-d(CACTAG (8-Oxo) TCAC) 8:390, 391 Cacticin 7:226 CAD 25:666 Cadabafarinosa 9:64,65 sesquiterpenes from 9:64,65 Cadabicilone 9:64,65 Cadabicine 9:73 Cadabicine methyl ether 5:209,210 cis-Cadalane 6:548,459
135 Cadalene 14:319 Cadambine tetraacetate 9:171-173 Cadaverine 14:739;26:1259,1260 Cadinane 4:584,585 synthesis of 4:584,585 by [2+2] cycloadditions 6:15 from Artemisia annua 7:217 Cadinane sesquiterpenes 15:278 Cadinene 21:282 10-Cadinol 21:584 Cadinol 30:722 structure of 30:722 Cadinolide A 9:9 biogenesis of 9:9 from Cadlina luteomarginata 9:6 X-ray crystal structure of 9:7-9 Cadlina luteomarginata 9:6;21:318, 334,364 ;24:183,184 ;28:659 sesquiterpene isothiocyanate from 28:659 Cadlinaldehyde 21:318 Cadlinolide A 17:15 cADPR 25:527,535 Caenorhabditis elegans 25:785;26:427, 429,432-434,437,439,441,447-449, 451,453,455,457,460-462,466, 468-471,473,474,481,487,488,490, 494,495,884 ;29:321 Caesalpin J 5:17 Caesalpina braziliensis 19:776 Caesalpinia bonduc L. 22:514 for convulsions 22:514 Caesalpinia echinata Lam. 27:37 Caesalpiniapulcherrima L. 20:475; 22:471,514;26:1142 for convulsions in children 22:514 Caesalpinia sappan 5:17 Caesalpinia vesicaria 26:1142 Caesalpiniaceae 25:92 Caesalpinina digyna 23:520 Cafestol 29:101 activity in CYP bioassay system 29:101 activity in GSH bioassay system 29:101 activity in GST bioassay system 29:101
activity in skin-6 bioassay system 29:101 from green coffee beans 29:101 Caffeate esters 30:651 Caffeic acid 5:467,469,474,479,111, 119,579,36;22:126,346,645,663; 23:537,551,740,744 ;25:655,657,663, 671,919,920,922-927,932-934, 936-938;28:262;29:578 effects on ACE 29:578 in apples 28:262 in blueberries 28:262 in cider 28:262 in coffee beverages 28:262 (+)-Caffeic acid 27:421 biological activity of 27:421 Caffeic acid derivatives 23:753 in artichoke 23:753 Caffeic acid tetramer 24:742,743 anti-HIV activity of 24:742 potassium salt of 24:742 Caffeine 21:72,98,109;22:5,7;25:532, 539;28:422 acaricidal activity of 28:422 3-O-3-Caffeoyl-4-O-feruloylquinic acid 25:920 Caffeoylquinic acid 22:353 3,5-Di-O-Caffeoylquinic acid 22:353 4,5-Di-O-Caffeoylquinic acid 22:353 Caffeoylquinic acid 23:740 3'-Caffeoylquinic acid 23:749,750 4'-Caffeoylquinic acid 23:749 1-Caffeoylquinic acid 23:753 3-Caffeoylquinic acid 23:753 4-Caffeoylquinic acid 23:753 4,5-di-Caffeoylquinic acid 23:753 5-Caffeoylquinic acid 23:753 5-O-Caffeoylquinic acid 25:919,920 3-O-Caffeoylquinic acid 25:920,921 4-O-Caffeoylquinic acid 25:920 Caffeoylquinic acids 25:943,944; 27:419;28:262 derivatives 25:465,662 in apples 28:262 in blueberries 28:262 in body tissues 25:924 in cider 28:262 in coffee beverages 28:262
136 Cage-culture turbidostats (CCT) 26:378,382 Caged ABA 27:331,332 Cailicogorgia granulosa 25:670 Caissarone 25:713 Caj anin 27:498 Calabar bean alkaloids 14:636-638 synthesis of 14:636-638 . Calamanenenes 15:251 biosynthesis of 15:251 1R,4S-Calamanenes 15:260 Calamanin B 23:405 Calamanin C 23:405 (+)-Calamenene 15:244,247 from Eremophila drummondii 15:244 Calamenenes (1R,4R) 15:259 Calamus 21:595 Calarene 25:170 Calathrix WA 26:366 Calcemic effects 30:484,495 of lc~,25(OH)zD2 30:495 of lot,25(OH)2D3 30:484,495 of l~,25(OH)2D4 30:495 Calceolaria andina 28:408 Calceolariode A&B 26:327,328 Calceolsareoside A 25:543 Calceolsareoside B 25:543 Calcicolin A i5"119,126,133,171 Calcidiol (25-hydroxyvitamin D3) 11:380 (-)-Calcimycin 16i712-713 synthesis of 16:712-713 Calcinosis cutis 26:675 Calciol (vitamin D3) 11:380 Calcitonin 27:800 Calcitriol 9:520,521,43 Calcitriol lactone 1:604,607 synthesis of 1:604,607 Calcitroic acid 30:502 Calcium alginate 7:92 Calcium antagonistic activity 23:804 of nootkatol 23:804 Calcium chloride 2:414 Calcium effects 12:397 of staurosporine 12:397 Calcium spirulan 30:400,403 chemical analyses of 30:400
structure-activity relationships of 30:403 Calcium uptake inhibitor 28:119 cyclopiazonic acid as 28:119 Calcium/calmodulin-dependent protein kinase 12:389 Calcium-induced contractions 30:748 Calderiella sp. 11:464 macrocyclic lipids from 11:464 Calderol 9:513 Calditol 11:430,464 Calea prunifolia 5:728 Calebassine 25:528 as immunosuppressive drug 25:528 Caledonin 25:813,814 Calendonian 25:697 Calendula arvensis 17:126;21:665 oleanolic acid glycosides from 21:665 Calendula officinalis 22:109,679;25:58 lutein from 7:361 Calenduladiol (lup-20(29)-ene-3 [3, 1613-diol) 29:586 effects on CHY 29:586 Calf intestinal alkaline phosphatase 14:308,309 Calf-thymus vitamin D receptor 30:494 binding assay for 30:494 Calicheamicin Q 25:796 Calicheamicin 7' 25:796 Calicheamicin yl 25:838 Calicheamicinone 10:150 Calicheamycins 10:153;12:489;24:934; 25:796,838 as anti-cancer agent 24:934 Calicoferols 25:705 California red scale pheromone 4:675, 479 Californian sponge 28:671 antiinflammatory activity of 28:671 antimicrobial activity of 28:671 Californium Delasma Desorption (CDD) 24:138 Calli 30:609 Calliandra portoricensis 22:515 as anticonvulsant agent 22:515
137 Callinectes sapidus 19:647,672 Callipelta sp. 25:775;26:1175,1210, 1211,1213 Callipeltins A-C 26:1211,1212,1213 Callipeltoside A 25:775 Callipeltosides 25:757,775 Callipeltosides A-C 26:1210,1211,1213 Calliphora 27:384 Calliphora bioassay 29:25 [3-acetoxy- 14ct-hydroxy-5 [3cholest-7-en-6-one activity in 29:263 as ecdysteroid activity assay 29:25 22-dehydro-25-deoxy-ecdysone activity in 29:26 3-dehydroecdysone activity in 29:26 2-deoxy-20-hydroxy-ecdysone activity in 29:26 22- de oxy-20-hydro xy-ecdysone [taxisterone] activity in 29:26 3-epi-2-deoxy-20-hydroxyecdysone activity in 29:26 25-deoxy-7,8-dihydro-ecdysone activity in 29:26 2f3,14c~,-dihydroxy-5 a-cholest-7en-6-one activity in 29:27 6-oxo-3 c~,14ot-dihydroxy-5 [3cholenoic acid methyl ester activity in 29:27 3-oxocholest-dihydroxy-cholest4,7-dien-6-one activity in 29:27 313,14c~-4,6,8(14)-triene activity in 29:27 3 [~,7 e-dihydroxychole st- 5-ene activity in 29:27 ( 2 5R/S) 2 0,2 6-dih ydro x yecd yso ne activity in 29:26 20-(2',2'-dimethyl-(22R)furanyl) ecdysone activity in 29:26 6,24-dioxo-3 [3,14t~-dihydroxy513-chol-7-en-24-dimethylamine activity in 29:27 ecdysone activity in 29:26,28 3 [3-ethoxy- 14 ot-hydroxy-5 ~-
cholest-7-en-6-one activity in 29:26 for Bombyx mori pupae's ecdysone 29:25 for Calliphora erythrocephala 29:25 14c~-hydroxy-3c~,5 ~cyclocholest-7-en-6-one activity in 29:27 3-oxo- 14~-hydroxy-5 f3-cholest7-en-6-one activity in 29:26 14~-hydroxy-5 [3-cholest-7-en-6one activity in 29:26 3 [3-hydroxy-5 ~-cholest-7-en-6one activity in 29:26 3 ~-hydroxy-5 [3-cholest-8,14dien-6-one activity in 29:26 ( 14cz-H)3 ~-hydroxy-cho le st-4,7dien-6-one activity in 29:27 14c~-hydroxycholest-4,7-dien3,6- dione activity in 29:27 20-hydroxyecdysone 25-acetate [viticosterone E] activity in 29:26 20-hydroxyecdysone 3-0cinnamate activity in 29:26 22-epi-2O-hydroxy-ecdysone activity in 29:27 20-hydroxyecdysone activity in 29:26 5 ~-hydroxypterosterone activity in 29:26 (25R/S)-inokosterone activity in 29:26 makisterone A activity in 29:26 3 [3-methoxy- 14c~-hydroxy-5 [3cholest-7-en-6-one activity in 29:26 24R-methyl-2 [3,14c~-dihydroxy5~- cholest-7,22-dien-6-one activity in 29:27 3ct-methyl-3 ~, 14c~-dihydroxy5[3- cholest-7-en-6-one activity in 29:26 5 [3-methyl-3 [3,14~-dihyroxycholest-7-en-6-one activity in 29:27 2ct,3 ~, 14ot,20R,22R-pentahyd-
138
roxy-5 [3-cholest-7-en-6-one activity in 29:26 213,313,20R,22R,25-pentahydroxy5 [3-cho 1est- 8,14-di en- 6- one activity in 29:26 polypodine B activity in 29:26 ponasterone A activity in 29:26 poststerone activity in 29:27 2,3-seco-ecdysone activity in 29:27 4-nor-3 [3,14ot,25-trihydroxy-5 [3cholest-7en-6-one activity in 29:27 313,5(x,14c~-trihydroxy-cholest-7en-6-one activity in 29:27 Calliphora erythrocephala 29:25 Calliphora victina 29:31 Callitristic acid 15:172 from Rabdosia kunmingensis 15:172 Callna vulgaris 29:691 Callosobruchus chinensis 21:379; 24:714,715 Callosobruchus maculatus 24:714 Callosobruclus analis 9:299 Callus culture 2:366 growth within 2:366 Callyspongiajohnstorii 25:717 Callyspongia sp. 25:724;28:673 Callyspongia truncata 25:723;28:712 Callyspongin A 28:712 as starfish fertilisation inhibitor 28:712 Callyspongin B 28:712 as starfish fertilisation inhibitor 28:712 Callystatin A 25:724 Calmodulin 1:4,399;22:35;25:706; 26:917,919,920 inhibitor of 25:706 Calmodulin antagonist activity 25:758 Calmodulin domain-containing protein kinase (CDPK) 25:544 Calmodulin inhibitory activity 2:282, 284 Calmodulin kinase III 27:854 Calmodulin-dependentphosphodiesterase (CAM-PDE) 25:509
Calmodulin-dependent phosphodiesterase (CAM-PDE) 25:509 Calmodulin-pathways 26:250 Calocedrus decurrens 28:408 Caloglossa liprieurii 26:478 Calomyrmex sp. 5:223,224,230,253 Calonectrin 6:230,21 ;9:206 deoxynivalenol from 6:230,21 Calonectrin 9:206 Calophylloide 22:542,536 Caloscypha fulgens 7:338 [3,y-carotene from 7:338 Calpurina aurea 7:427;28:400 killing effects on ticks 28:400 Calvin photosynthesis 13:330 Calvularia virdis 25:704 Calycanthoside 7:224 Calyceramide A 28:713 as neuraminidase inhibitors 28:713 Calyceramide B 28:713 as neuraminidase inhibitors 28:713 Calyceramide C 28:713 as neuraminidase inhibitors 28:713 Calycinoxanthon 30:621 structure of 30:621 Calycinum L. 22:656,672 Calycocystis Bunge 27:444 Calycopterin 5:757 Calycosin 27:498,499 Calycotomine 12:449 ent-Calyculin A 26:1234,1235-1239, 1240 total synthesis of 26:1234, 1235-1239,1240 Calyculin A 18:269;27:877,878 as okadaic acid 27:877 Calyculin derivative 25:731 Calyculin J 25:732 Calyculins 5:395,396 Calyculins A-H 26:1204,1205,1240, 1234,1235 Calyculins B&C 26:1240 Calystegia sepium 22:718 Calystegine A3,As-A7 22:184,730 Calystegine BI-B5 22:721 (+)-Calystegine B2 22:734
139 Calystegine Cl,C 2 22:185 Calystegine Nl 22:185 Calysterol 9:38,39,44,45 Calyx nicaeensis 9:37,44 calysterol from 9:38 dihydrocalysterol from 9:37,44 (23R,24 R)-23,24-me thylenecholesterol from 9:37 nicasterol from 9:37 Calyx podatypa 9:38,45;26:64,65 Calyxin A 23:805 Calyxin B 23:805 Calyxin C 23:806 Calyxin D 23:806 Calyxin F 26:902 Calyxin G 26:902 CaM antagonists 25:489,492 CaM dependent kinases 25:543,544 CaM inhibitors 25:491 Camaraside 23:522 Cambogin 22:659 CaM-dependent isoform of PDE (CAM-PDE) 25:490 CaM-dependent PKs I-IV 25:524 CaM-dependent protein kinases 25:493, 527 Camellia japonica 23:404,438 Camellia oleifera 23:406 Camellia sinensis 20:735;21:499; 23:341 ;25:472,478;29:579,582-585, 588,654,655 Camellia sinensis var. sinensis 21:660 Camelliagenine A 21:673 Camelliantannin H 23:405,412 Camelliasaponins 21:675 Camelliatannin D 23:405,438,441 2D J-resolved NMR spectrum of 23:441 structure of 23:438 Camellidin I&II 15:202 Camelliin A 23:404,408 Camelliin B 23:405,411,436 structure of 23:436 Camelliins 23:407 Camellioferin A 23:405 Camelspin 6:140 (-)-Camoensidine 15:520 Camomile 13:660
cAMP 30:192 in regulation of ionotropic receptors 30:192 cAMP formation 30:383 G-protein inhibition 383 cAMP-dependent channels 25:495 cAMP-dependent protein kinase (PKA) 25:488,489,522,547,548 cAMP-dependent protein phosphorylation 25:494 Campestanyl ferulate 9:474 Campesterol 9:454,129,520;20:234; 22:482;30:505 Campesteryl linoleate 9:461 cAMP-gated Na § channels 25:517,523, 524,546 Camphanate method 6:153 (1S)-Camphanic acid 14:179 S-Camphanic acid 16:478 (1S)-(-)-Camphanic chloride 18:607, 613,627 Camphene 21:598,601 (-)-Campherenol 4:675 Campherenone 16:136 enantiospecific synthesis of 16:136 (-)-Campherenone 4:675 (-)-c~-Campholenic acid 16:125,127,148 (+)-Camphor 10:408,123-124 radioimmunoassay of 7:114,115 (-)-Camphor 10:52,123-124 d-Camphor 11:6,7 (+)-Camphor 19:229;20:586 Camphor 7:95;9:530,536;16:123,124; 20:16;25:125,128,154,156,547; 27:376 D-(+)-Camphor 25:156 Camphor enol trimethyl silyl ether 4:656,657,665 Camphor sulfonic acid (CSA) 30:6 (-)-Camphor-10-sulfonate 16:125 D-Camphor-10-sulphonic acid 4:628, 632;19:139 Camphor-10-sulphonyl bromide 4:628, 629 thermolysis of 4:628,629 m-and p-Camphorene 15:227 from Eremophila cuneifolia 15:227
140 Camphorene 5:127,696 Camphoric acid 20:586,597 Camphorquinone 4:660,661,666,149(-)Camphorquinone rearrangement 16:150 (-)-Camphorsulfonic acid 12:417 (+)-10-Camphorsulfonic acid 15:425 Camphorsulfonic acid 6:68,221,205 cAMP-induced Ca2+-influx 25:491 cAMP-induced influx 25:497 of K + 25:497 Campnospermanol 9:323,329 Campnospermum auriculata 9:323 S-Campothecin 16:431 asymmetric synthesis of 16:431 cAMP-phosphodiesterase 25:539 cAMP-response element binding (CREB) 25:523,548 cAMP-sensitive ion channels 25:490, 496,497 Camptotheca acuminata 23:405;24:269; 26:144 (+)-Camptothecin 18:333,349,355 rad52-Camptothecin 20:465 Camptothecin 5:84,85,127;12:283; 13:654 ;20:500;22:28 as anticancer agent 13:654 from Camptotheca acuminata 13:654 synthesis of 12:283 Camptothecine 26:825,827 Camptothecine-type alkaloids 5:84,85 Camptothin A 23:405 Camptothin B 23:405 Campylosporus hypericin 30:609,610 Campylotorpis hirtella 25:94 Canabichromene 4:398,399 synthesis of 4:398,399 from Cannabis sativa 4:398 Canadensene 20:107 Canadensolide 19:463 (-)-Canadensolide 19:485 (R)-(+)-Canadine 10:678 Canadine 21:96 (+)-Canadine 6:489,490 Canadine methiodide 6:491,492 allocryptopine from 6:491,492 cis (trans)-Canadine N-oxide 6:474,475 nitrone from 6:474,475
trans-Canadine N-oxide 6:474,488,489 cleavage product of 6:488,489 photolysis of 6:474 Canagana sinica 27:855 Canaliculatol 23:53,547;26:562 Canavalia gladiata 25:93;29:598 Canavalia lineata 29:598,603,604,607 Canavaline 20:486;26:932 Cancer 17:137;24:404,405;30:55,56, 58,224,732 Aresch. in 30:56 epidemiology of 24:404-405 Ganoderman lucidum in treatment 30:58 prevention of 30:56 role of free radicals 30:224 role of natural products in 30:55 treatment of 30:56 use of Laminaria japonica Cancer cell lines 30:588 cytotoxicity against 30:588 Cancer cell lines inhibition 27:916-918 by biflavonoids 27:916-918 by chalcones 27:913-916 by flavanones 27:908-912 by flavones 27:897,898,899-903 by flavonols 27:903-908 by isoflavones 27:912-913 by 1,2-diphhenylpropane derivatives 27:920-921 by 1,3-diphenylpropane derivatives 27:919-920 Cancer chemoprevention/anti-inflammatory bioassay 29:75;30:588,591 for anti-inflammatory activities 29:76 for anti-mutagenic activity 29:75 for apoptosis induction 29:79 for cancer chemopreventive activity 29:76 for COX-2 iNOS inhibition 29:79 for GSH induction 29:78 for GST formation 29:78 for inhibition of active oxygen species formation 29:78 for inhibition of tumor promotion 29:77 for NF-KB inhibition 29:80
141 for ODC inhibition 29:79 for PKC inhibition 29:80 for TNF-ot inhibition 29:80 Hernandia species for 588 replication initiation in 29:75 Cancer chemopreventive activity 26:507,508,510,511 ;30:591 in rat mammary carcinogenesis model 30:592 in two-stage mouse skin 30:591 Cancer chemopreventive agent 30:591, 593 from Hernandia species 30:593 in vitro 30:593 activity in mouse mammary organ culture assay 30:593 activity in mouse skin carcinogenesis test 30:593 Cancer chemopreventive agents 24:1061-1062;25:43 Cancer chemotherapy 4:544;24:403464;28:559;30:56,64,841 by substituted benzo [c]phenanthridines 4:544 cisplatin for 28:559;30:56 doxorubicin 30:56 famesyl-protein transferase for 24:403-464 side effects of 30:56 Cancer chemotherapy drug 28:559 as doxorubicin 28:559 Cancer growth inhibition 23:290,292 by bruceanol D 23:290,292 ofbruceanol E 23:290,292 ofbruceanol F 23:290 Cancer prevention 30:762 due to green algae 30:762 Cancer related activity 21:634 Cancer target 30:591 chemopreventive drugs as 30:591 Cancerostatic activity 26:452 Cancer-preventing activity 21:641 Candicin 15:328 Candida albicans 2:422,428,438-440, 292,5:233,282,323,324,342,356,369, 400;7:282;19:578;20:712;21:232, 235,237,608,611,662;22:57,61,74, 79,248,299,398,627,628;23:10,114,
123,164,235,335,347 ;25:258,759, 764,773,780,790,822;26:228,402, 403,673,1093,1124,1126,1134,1187, 1203,1216,1217;28:686;29:571,751; 30:739 antibacterial activity against 30:739 antifungal activity against 30:739 Batzella sponge against 28:685 Candida albicans 1463D 28:476 Candida albicans ATCC 90028 28:476 Candida albicans ATCC 90029 28:476 Candida bogoriensis 5:294 Candida boidinii 22:601 Candida curvata 5:292 Candida cylindracea 12:337;18:429 Candida dubliniensis CBS 7987 28:476 Candida genus 29:328 Candida glabrata 22:57;26:1126 Candida guillermondii 2:422;22:57; 26:1126 Candida humicola 5:292 Candida kefyr IFM 46921 28:476 Candida krusei 12:400;22:57;23:115 Candida lipolytica 5:292,308 Candida lusitaniae 5:283 Candida neoformans 22:57 Candida obtusas 5:283,292 Candida parapsilosis 5:292,323,324; 22:57;28:476 Candida patens 2:441 Candida pellicula 25:308 Candida pseudotropicalis 12:400 Candida rugosa 1:694,306 Candida sp. 5:291,292,328;21:192,232, 758;22:248;26.330,331,1087,1126, 1127,1134 Candida tropicalis 2:422,400;22:57 Candida tropicalis IFM 46816 28:476 Candida utilis 7:69,302,235;21:608,611 Candida valida 26:1091 Candidiasis 2:332,425,432;6:261 polyene macrolides in 6:261 Candidissimus 26:457 Candidissiol 20:680 from Salvia candidissima 20:680 Candidoses 6:261 polyene macrolides in 6:261
142 Candsburgia quercifolium 29:722 Canella winterana 2:447 Canellaceae 7:427;17:234 Canellal 2:447,448 Cangorinin 18:760 Cangoronine 23:695 Cangorosa 23:657 Cangorosin B 18:665;30:683 ROESY of 30:683 CD spectral data of 30:683 FAB-MS of 30:683 10-epi-Canin 27:576 Canin 7:234 Canin-8~-isovalerate 27:576 Canin-8ct-methyl butyrate 27:576 Canine-hysteria 7:6 Canna indica 28:425 Cannabidiol 22:538,515 (-)-trans-Cannabidiol dimethyl ether 19:187 Cannabifuran 19:194 Cannabinaceae 30:610 acylphloroglucinols from 30:610 Cannabinoids 19:185-244;30:193,194, 195 anti-nociceptive 194 as analgesic 30:195 anti-nociceptive effects of 30:193 from Cannabis sativa 30:195 role in neuronal excitability 30:194 structure-activity relationships (SAR) of 30:195 Cannabinoid affinity 30:196 for CB2 receptor 30:196 Cannabinoid antagonist 30:198 development of 30:198 Cannabinoid receptor 19:186;30:194 in central nervous system 30:194 in peripheral nervous system 30:194 Cannabinoid receptor (CBl) 19:186 Cannabinoid skeleton 19:186 retrosynthetic disconnection of 19:186 Cannabis 7:7 Cannabis sativa 19:186;22:515;25:532; 30:194,198
as analgesic 30:194 as intoxicant 19:186 as natural therapeutic herb 30:194 cannabinoids from 30:194 therapeutic use of 30:198 (-)-Cannabisativine 16:492-493 synthesis of 16:492-493 (-)-Cannibidiol 16:131 Cannizzaro reduction 19:536 Cannobinoid receptors 25:533 Canophyllol 5:744,748,750;23:702 Canscora decussata 22:515 for epilepsy 22:515 Cantabradienoic acid 7:216,238 from Artemisia cantabrica 7:216,238 Cantaxanthin 21:305 Cantharellus cibarius 5:289;23:343 Cantharellus cinnabarinus 20:721 Cantharidin 26:457 Cantharis vesicatoria 27:882 Canthaxanthin 20:576,725,749;30:520, 536,540,543,544,546 ID/2D ESEEM techniques for 30:540 stretching vibrations in 30:540 studies on 30:536 UV irradiation of 30:540 Canthaxanthin cation radical 30:536, 540 ENDOR spectrum of 30:540 EPR data of 30:540 structures of 30:536 Canthigaster solandri 21:364 Canthin alkaloids 24:282 Canthin-6-one 7:389,390,394 Canthium bibracteatum 22:515 for convulsions in children 22:515 Canthium gueinzii 22:515 for epilepsy 22:515 Cantleyinde derived alkaloids 6:527 Cantleyine 6:503,527,529 from Strychnos muxvomica 6:503,527,529 Cantleyine series 6:522 Cantoniensistriol 25:96
143
Canventol 29:111 activity in skin-5 bioassay system 29:111 activity in RAS bioassay system 29:111 activity in TNF~ bioassay system 29:111 Capal 23:659 Capalliferol A 548 Capellene-8 [3,10a-diol 3:63 Capillanol 7:222 Capillarin 7:202,203,223 Capillene 7:202-204,222 Capnella imbricata 22:209 Ag~Z)-capnellene from 13:34 capnellanes from 6:42 precapnelladiene from 6:33 Capnellanes 6:42 from Capnella imbricata 6:42 from (-)-A9~lZ)-capnellene 6:42 synthesis of 4:588 Capnellen-3[3,8[3,10c~- triol 3:63,64 Capnellene 3:11,13,19,20,22;22:195, 209,215,217 synthesis of 3:11,13,19,20,22 A8/~9)-Capnellene 3:20 synthesis of 3:20 A9<12)-Capnellene 3:7;13:34,35 synthesis of 13:34,35 from Capnella imbricata 13:34, 35 (-)-Ag~12)-Capnellene 6:42 capnellanes from 6:42 (+)-A9~12)-Capnellene 6:45 by ~x-alkaynone cyclization 6:45 by [2+2] cycloaddition reaction 6:43,44 by [4+2] cycloaddition reaction 6:43,44 by cyclopropane sliding reaction 6:48 by Diels-Alder reaction 6:46 by intramolecular alkylation 6:42,43 by intramolecular diyl trapping reaction 6:46 by intramolecular reductive coupling 6:48
by intramolecular type I Mg ene reaction 6:45,46 by methylenation 6:46,47 by 1,2-methyl shift 6:48 by Nazarov cyclization 6:43 by photochemical annulation 6:48 by three-carbon annulation 6:42 Dreiding synthesis of 6:45 from [3-diketone 6:48 from humulene 6:48 Grubb synthesis of 6:46,47 Liu-Kulkarni synthesis of 6:43,44 Oppolzer-Batting synthesis of 6:45,46 Stille synthesis of 6:47 synthesis of 6:42,43 with Tebbe reagent 6:46,47 A 9(m2)-Capnellene 213,813,10a-triol 3:7 A9(lZ)-Capnellene-3[3,813,10c~-triol 3:7 A 9(12) -Capnellene 313,813,10c~-triol 22:209 Capnellene-2[3,8[3,10c~-triol 3:64 Capnellene-3[3,8[3,10c~-14- tetriol 3:64 A 9(12)-Capnellene-3[3,813,10[3-14-tetrol 3:7 Capnellene-5c~,8[3,10c~-triol 3:64 Ag(~2)-Capnellene-5c~,813,10c~-triol 3:7 A9112)-Capnellene-8[3,10c~-diol 3:7 Capnellenols 6:49,50 by aldol cyclization 6:49,50 by three-carbon annulations 6:49,50 synthesis of 6:48-50 Caporal 22:67 Capparis baducca 22:515 Capparis decidua 9:73-75,77 alkaloids from 9:73-75,77 Capparis masaikai Levl. 27:18 mabinlin from 27:18 Capparisine 9:73 Capping reaction 4:279,280 in oligonucleotide synthesis 4:279,280 Capraria biflora 15:259 Capreomycin 2:424 Capric acid 21:595
144 Caprifoliaceae 7:427;25:249,251,259 Capsaicin 7:93;27:747,749;28:436,437; 30:195,201,202,206 as complex I inhibitor 28:436, 437 activity of 30:202 antinociceptive action of 30:206 as natural analgesic product 30:195 as vanilloid receptor agonist 30:202 effect on TRPVI expression 30:206 from Capsicum sp. 7:93 inhibition of NO production by 30:201 Capsaicin analogue 30:193,201 olvanil as 30:193 SDZ 249-665 as 30:193 structure-activity requirements of 30:201 Capsaicin induced edema 25:46 inhibition of 25:46 Capsaicin receptor 30:201 lipophilic part of 30:201 Capsaicine 21:89 Capsanthin 20:726,733,757 Capsazepine 30:201,202 as vanilloid receptor antagonist 30:201,202 effect on iNOS protein synthesis 30:201 nitric oxide inhibition by 30:201 Capsicum annuum 13:320;20:586; 29:610 Capsicum frutescens 20:135 Capsicum sp. 28:400,436;30:193 capsaicin from 7:93 Capsicum species 28:436,400 killing effects of ticks 28:400 Capsid proteins 24:477-479 enzymes of 24:478,479 Capsimycin 23:51;28:138 antifungal activity of 28:138 Capsorubin 20:568,586,726,77 Capulin 22:559 (+)-Capuronidine 5:126 Capuronine 5:124 20R-Capuvosidine 5:125
Capuvosine 5:129 Caraganaphenol A 26:535,563 Caralluma tuberculata 5:212;9:62-64 saponins from 5:212;9:62-64 Carapa abovaa 7:189 Carassius carassius 21:364 Caratuberside A 5:212,213 Caratuberside A-D 9:62-64 Caratuberside B 5:213 Carausius morosus 9:492 5a-Carba -c~-D-glucopyranosylamine cis-2,3,4 trihydroxy-5 (hydroxymethyl) 1-cyclohexylamine] 13:195 Carbaaldofuranoses 29:452 synthetic strategies for 29:452 target-oriented (linear) synthesis of 29:452 Carbaaldopyranoses synthesis 29:467 building-block for 29:469 by Angelaud and Landais 29:467 by Btichi and Powell 29:472 by Emmons-Horner-Wadsworth 29:471 by furan-based Diels-Alder approach 29:470 by Metha and Mohal 29:470 by microbial transformations 29:469 by Sudha and Nagarajan 29:472 by Toyokuni 29:471 by Zanardi and co-workers 29:473 chiral sources for 29:467 conditions for 29:468 diastereoselective routes to 29:471 exploitation of natural carbohydrates for 29:471 ofglycosidase inhibitors 29:467 Carbacepham 8:262;12:121 synthesis of 12:121 Carbachol 25:613;26:267 Carbacyclins 16:388 Carba-disaccharides 13:219-221 synthesis of 13:219-221 Carba-DL-hexopyranose 13:1875aCarbafuranose synthesis 29:452 by agrofoglio 29:461 by D6sir6 and Prandi 29:455
145 by Lowary and Callam 29:457 by Lundt and Horneman 29:456 by Metha and Mohal 29:462 by Monti 29:458 by Rassu 29:453 conditions for 29:453 from c/s-fused bicyclic furanone 29:452 of 2 C-methyl-4c~-carba-[3-Darabinoaldofuranose 29:459 of 2 C-methyl-4o~-carba-~3-Dlyxoaldofuranose 29:459 of 4 ~-carba-ct-D-xylofuranose 29:452 starting from norborn-5-en-2-one 29:452 Carbafuranoses 29:451 aminocarbafuranoses as 29:452 as bioactive compounds 29:451 carbaketofuranoses as 29:452 carbocyclic analogues of 29:451 carbocyclic nucleosides as 29:451 conjugates of 29:451 thiocarbafuranoses as 29:452 unsaturated 29:452 Carbafuranoses 29:451 diversity-oriented synthesis of 29:451 5a-Carba-glycosylamines 13:195-204 synthesis of 13:195-204 5a-Carba-hexopyranoses 13:190-207 synthesis of 13:190-207 Carbaketofuranose synthesis 29:460 by A1-Abed and Seepersaud 29:460 by Wilcox and Gaudino 29:460, 461 conditions for 29:460 Carbaketopyranoses 29:474 as sweeteners 29:474 ketose-type pyranoses as 29:474 stereoconstitutional features of 29:474 5-Carba-levoglucosenone 14:279 1,4-exo-aducts of 14:279 3-deoxy derivative of 14:279 synthesis of 14:279
Carbamate ester 21:168 Carbamazepine 22:507 Carbamoylmethylviologen 20:867,869 Carbanion 16:30 Carbanion reagents 11:439-443 Carbanion rearrangement 16:620 Carbanions 1:351-353 Carbaoctanoses 29:502 functional groups in 29:31 stereocentres in 29:502 Carbaoxirose/carbaoxetoses 29:490 1-deoxy- 1-amino-6(~-c arba- [3-Dglycero-D-gulcoheptoseptanose as 29:495 6cz-carba-[3-D-glycero-Dgulcoheptoseptanose as 29:494 against hepatitis B virus 29:493 against herpes viruses 29:491 against HIV 29:491 as glucosidase inhibitor 29:497 asymmetric synthesis of 29:490 calystegine B2 as 29:496 enantioselective synthesis of 29:492 in cytomegalovirus infections 29:492 synthesis by Boyer and Hanna 29:497 synthesis by Ichikawa 29:492 synthesis by Skaanderup and Madsen 29:496 Carbapenams 8:262,263 synthesis of 8:262,263 Carbapenem 4:434 as asparenomycins 4:434 as carpetimycins 4:434 as KA-antibiotics 4:434 as nor-thienamycin 4:434 as OA-antibiotics 4:434 as pharmacophore 4:434 as pluradomycins 4:434 Carbapenem antibiotics 13:495-507 (+)-6a-Carbaprostaglandin I2 1:698,699 synthesis of 1:698,699 Carbaseptanoses 29:493 total synthesis of 29:493 Carbasugars (alias pseudosugars) 13:187-255;29:449,507
146
analogues of 29:506 basic motif of 29:449 biological effects of 29:449 categories of 29:449 chirality in 29:449 cyclobutane cores of 29:449 cycloheptane cores of 29:449 cyclohexane (pyranoid) motif of 29:449 cyclooctane cores of 29:449 cyclopentane (furanoid) motif of 29:449 cyclopropane motif of 29:449 reviews about 29:506 synthesis of 13:187-255;29:449, 507 Carbazolequinone alkaloid 1:163 5a-Carba-ot-D-galactopyrano se 13:187,191 5a-Carba-ot-D-glucopyranose 13:188, 215,219 5a-Carba-et-D-glucosamine 13:210,212 5a-Carba-ot-DL-galactopyranose pentaacetate 13:188 5a-Carba-ct-D-mannopyranose 13:216 4o~-Carba-ot-D-xylofuranose 29:452 carbafuranose synthesis of 29:452 5a-Carba- [3-DL-mannopyranose derivative 13:191 Carbendazein B 25:6772 Carbendazime 22:462;25:669 Carbene complexes 16:406 Carbene insertion reaction 4:436,438 Carbene-diene cyclization 3:29 Carbene-olefin cyclization 3:325 Carbenoid displacement 1:259 Carbenoid insertion 13:501-503 Carbenoxolone 22:425 (E)-[3-Carbethoxyacroylyl chloride 14:560 Carbethoxycyclohexanone 14:745 isonitramine from 14:745 nitramine from 14:746 Carbinolamides 4:57 Carbinolamine 4:57,269,270
Carboalumination 1:454,455,459 with Me3A1, ZrCp2C12 1:454, 455,459 N-Carboamoyl-Gly-IA human insulin 2:38-41 HPLC of pepsin digest 2:38,39 peptides by LSIMS 2:38-41 structure of 2:37-39 N-Carbobenzyloxyslaframine 12:308 Carbocation intermediate 6:474 in 2,5-benzoxazonines syntheses 6:474 Carbocupration reaction 14:507,508 asymmetric induction in 14:507, 508 diastereoselective 14:507,508 of C2-homochiral cyclopropenes 14:507,508 Carbocycles 8:272 from palladium (+2) complexes 8:272 Carbocyclic nucleoside 8:148 antibiotic activity of 8:148 antitumor activity of 8:148 antiviral activity of 8:148 Carbocyclic oxetanocin A,G 10:620, 621 antiviral activity of 10:620,621 Carbocyclic oxetanocins 10:608-619 synthesis of 10:608-619 Carbocyclic spiro compounds 14:544-546 asymmetric synthesis of 14:544-546 2-Carboethoxy-2-deoxy-2-ulosoic acid esters 30:467 decarboxylation of 30:467 6-Carboethoxyolivetol 4:386,387 with geranyl bromide 4:386,387 Carbohydrate derivative 14:659-664 synthesis of 14:659-664 via Norrish type II reaction 14:659-664 Carbohydrate lactones 10:385 C-glycosides from 10:385 Carbohydrate transporting proteins 7:29 Carbohydrate-molybdate complexes 15:426-435 4-Carbohydroxypatchoulol 25:172
147 [3-Carbolines 23:260,261,266;25:33, 782,902 biosynthetic studies of 23:260, 266 fl-Carboline alkaloid eudistomidins 25:817 [3-Carboline alkaloids 2:369,90 13-Carboline derivative 8:285;25:10,14 ~-Carboline marine alkaloids 25:819 fl-Carboline metabolites 25:818 ~-Carbolines 5:414,415,417,245 [3-Carbolines 5:417,418;21:84 Carbomanoyl oxide 25:261 (+)-Carbomenthone 6:547,548 Robinson annulation of 6:547, 548 2-Carbomethoxycycloheptanone 12:241 with 4-bromobutyraldehyde dimethyl acetate 12:241 dl-Carbomethoxydihydrocleavamine 14:806,807,850-853 Carbomethoxylation 4:36,38 of ketone 4:36,38 Carbomycin 13 10:170 Carbomycins 11:164 Carbon catabolite 25:313 Carbon tetrachloride 25:460 Carbon versus oxygen alkylation 4:367 regioselectivity of 4:367 Carbon-bridged system 12:87 Carbonimidic dichlorides 21:346 Carbonimidoyl dichloride 21:356 Carbonolide B 11:162-166 Carbonolides 11:163-172 stereoselective synthesis of 11:163-172 synthesis of 11:158-172 Carbon-tin bond 1:352,353 conversion to carbon-silicon bond 1:352,353 Carbonyl coupling reaction 8:16-18 titanium induced 8:16-18 Carbonyl reduction 1:622 diastereoselective 1:622 of ~-keto acetals 1:622 Carbonyl tosylhydrazone 30:32 reductive deoxygenation of 30:32
1,2-Carbonyl transposition 3:474,485 1,3-N-Carbonyl-3'-deoxygentamycin X: 14:146;16:432 Carbonylation 19:189,195 palladium catalyzed 19:189,195 N,N'-Carbonyldiimidazole 1:268;4:327 1,1'-Carbonyldiimidazole 8:90;22:291 Carbopalladation 16:374 (-)-Carbovir 10:608,609 antiviral activity of 10:608,609 20-Carboxaldehyde 19:471 3-Carboxamido analogue 30:198,199 of cyclazosine 30:198 structure of 30:199 2S-Carboxy-3R,4R,5S-trihydroxy piperidine 10:549 absolute configuration of 10:549 from Baphia racemosa 10:549 relative configuration of 10:549 Carboxyatractyloside 20:8 3-Carboxy-cis, cis-muconate 8:305 cycloisomerisation 8:305 3-Carboxy-cis, cis-muconic acid 8:295, 296,306 3-Carboxycoumarin 18:978 6-Carboxydihydrochelerythrine 27:167 4'-Carboxyl group 27:330 for photoaffinity 27:330 1-Carboxyl group 27:354 for abscisic acid bioactivity 27:354 (4S)-3-Carboxylactone 8:297 Carboxylation 11:195 (2S)-methylmalonyl CoA by 11:195 of propionyl CoA 11:195 Carboxylic acid 2:4;30:23 debenzylation of 30:23 oxidation of 30:23 Carboxylic acid anhydride variation 4:375 of Claisen condensation 4:375 Carboxylic acid silyl esters 4:564 with silylated phosphonium ylides 4:564 Carboxylic esters 6:334 into aldehydes 6:334 synthesis of 6:326327 8-Carboxylinalool 25:140
148
5-Carboxymellein 15:383 Carboxymethyl glucan (CMG) 23:139 2-Carboxymethyl-3-hexyl maleic acid 21:240 Carboxymethyllated grifolan (CMGRN) 23:140 4-Carboxymuconolactone $:295,296 Carboxypeptidase 9:489;25:375 Carbylamine reaction 12:113 isocyanides by 12:113 Carcinoembryonic antigen (CEA) 29:552 as tumor antigen 29:552 in colorectal cancer 29:552 periodate oxidation of 29:552 Carcinogen 21:97;24:1061,1062; 24:1061,1062;26:1002-1004 HA as 26:1002-1004 Carcinogen MNU 25:66 Carcinogenesis 20:512,513;26:965; 30:524,591,592,762 DMBA 30:762 in experimental animals 30:591 in mammalian cells 30:592 inhibition of 30:591 initiation of 30:592 natural inhibitors of 30:591 progression phases of 30:592 promotion of 30:592 Carcinogenesis research 15:439 Carcinogenic activity 13:532 of fumonisins 13:532 Carcinogenic study 27:306 of stevioside 27:306 Carcinogenicity 7:8,9;26:677;27:302 ofbenzo [1] pyrene 7:8,9 of madder root 26:677 Carcinoid cells 27:797,844 Carcinoma Ehrlich cells 25:836 Carcinomycin 1:498 Carcinus maenas 19:628;25:718 Carcurine 25:528 as immunosuppressive drug 25:528 Cardamine pratensis L. 22:515 for epilepsy 22:515 Cardamonin 23:808,821,802 Cardanol monoene 30:152 skin irritancy due to 30:152
Cardanols 9:313-315,323,326,330,332, 333,335-338,340,341,349,352,358, 363,368-371 ;21:592;30:150-152 biological properties of 30:150-152 [3-Cardene 25:944 Cardenolides 24:289;25:535;30:691 cytotoxic activity of 30:691 against KB cell line 30:691 Cardiac activity 21:98,669 Cardiac depressant 5:750 Cardiac diseases 30:224 role of free radicals in 30:224 Cardiac glycosides 9:293;21:89 Cardiac steroid 25:55,59 Cardiac toxicity 21:158 Cardiopetamine 26:868,869 Cardiotonic 23:499;24:898 aconitine as 24:898 Bacopa monnieri as 499 Cardiotonic activities 21:501 Cardiotonic constituent 17:33 Cardiotonic peptides 5:403 Cardiotonicity 24:875 as biological action 24:875 Cardiovascular activity 21:668 Cardiovascular disease 23:739;30:155, 524 Ginkgoaceae against 30:155 incidence of 30:524 Cardiovascular effects 26:232 Cardiovascular hypertrophy 26:236 Cardiovascular modulating effects 26:507-509 Cardiovascular system 26:183 effect of Schisandra on 26:183 Cardnol methylether 9:338 by azonolysis 9:338 Cardols 9:315,318,324,328,332,333, 335-339,341,347,349,358,359,368, 370;21:592;26:443 ;30:146 by decarboxylation 30:146 Cardwellia sublimis 9:320 Cardyceptin (3'-deoxyadexosin) 24:547 antiviral microbial-derived compound 24:547 Careaborin 7:189 (+)-Carene 12:243 A3-Carene 21:582
149
(+)-trans-Carene epoxide 19:204 Carex kobomugi 26:530 Carex pumila 26:551 (-)-c-viniferin from 26:551 Caribbean collection 28:632 minalemines D from 28:632 minalemines F from 28:632 Caribbean coral 25:690 Caribbean gorgonian 29:103 Caribbean sponge 25:698 Carica papaya 29:592,604 Caries 27:316 Carimbia subgenus 24:233 Carinogenesis 9:583 Carissa edulis 20:619 Carmenin 7:236 Carminative agent 23:642 of Teucrium sp. 23:642 Carminomycin 4:317 Carminomycinone 14:20 (S)-(-)-Carnegine 10:677,679 (R)-(+)-Carnegine 10:677,679,682 Carnegine 21:84 Carnitine palmitoyl transferase (CPT) activity 21:458 Carnosic acid 21:618;29:188 activity against HIV- 1 protease 29:190 antioxidant activities of 29:188 biological activity of 29:188 Carnosic acid synthesis 29:191 by Banerjee et al. 29:194 by Meyer et al. 29:191 by Tiam et al. 29:198 starting material for 29:191 Carnosifloside V 27:14,25,26 structure of 27:26 Carnosifloside VI 27:14,25 structure of 27:26 Carnosol 29:99,574 activity in DNA assay system 29:99 activity in mam-2 assay system 29:99 activity in skin-1 assay system 29:99 activity in NFkB assay system 29:99 activity in iNOS assay system
29:99 activity in NO assay system 29:99 activity in GST assay system 29:99 activity in CYP assay system 29:99 effects on HIV- 1 protease 29:574 Carnosolic acid 29:575 7-O-Methylrosmanol (abietane diterpene) synthesis from 29:575 rosmanol (abietane diterpene) synthesis from 29:575 Carob galactomannan 26:1139,1149 Carolisterol A-C 15:76;25:872 from Styracaster caroli 15:76 Carotadiol esters 5:725.727 Carotan lactone 5:725,726 Carotenal 30:546 (6'R)-13,~-Carotene 20:584 s-Carotene 20:584,721,725;26:299,300 ~3-Carotene 4:559,560;7:20,98,318, 319,334-342,344;17:611,612,708; 20:720,721,725,732,735, 746-748,760;21:304 ;24:215264;25:236;26:299,300,305;30:516,5 20,524,537,539-544,546,548 absorption spectra of 30:539 as electron donor 30:537 charge delocalisation in 30:544 charge distribution of 30:542 clinical use of 30:524 downfield shifts of 30:544 electrolysis of 30:541 in PS2 30:537 NMR analysis of 30:543 protonation of 30:546,548 role of 30:537 structure of 30:516 UV irradiation of 30:540 T-Carotene 7:327-329,333,334,338; 20:721,725 ~,~-Carotene 20:561,564,571,572, 576,584,604,607;23:179 (9Z,9'Z)-T-Carotene 7:332 from (15Z,9Z)-phytofluene
150
7:332 (9Z,7'Z,9'Z)-neurosporene from 7:332 Carotene 7:333,334,337,3526e-Carotene 7:338 (6S,6'S)-e,e carotene 7:338 from Ulua lactuca 7:338 (1R, l'R)-[3-Carotene 7:344 [3-Carotene anion radical 30:550 [3-Carotene dication 30:519,542,543, 545 by 2D ROESY 30:543 by COSY 30:543 by HMBC 30:543 by HSQC 30:543 by 1D NMR 30:543 reactions of 30:545 structure of 30:519 with water 30:545 B-Carotene hydrolase 25:718 [3-Carotene radical cation 30:519,535, 536,537 studies of 30:537 FT-IR of 30:537 ENDOR of 30:537 EPR of 30:537,539 NIR data of 30:539 spectroscopy of 30:537 structure of 30:536 Carotenoid 5,6-epoxides 6:142 Carotenoid anions 30:548,550 hypsochromic shifts in 30:550 radicals anion of 30:550 Carotenoid biosynthesis 7:317-367 Carotenoid carboxylic acids 30:528,529 examples of 30:528 reactions of 30:529 Carotenoid cation radical 30:521, 534-536,538,540,541 characterisation of 30:538 electrochemical properties of 30:541 electronic absorption of 30:538 orientation of 30:540 spectroscopic methods for 30:538 spectroscopic properties of 30:541
theoretical calculations of 30:534-536 use of electron nuclear double resonance spectroscopy (ENDOR) 30:538 use of electron paramagnetic resonance spectroscopy (EPR) 30:538 use of near infrared spectroscopy (NIR) 30:538 use of Raman spectroscopy 30:538 Carotenoid dianions 30:541,543,544, 548 characterisation of 30:543 effect of electrolytes 30:544 effect of temperature 30:544 preparation of 30:543 properties of 30:544 reactions of 30:544 theoretical calculations of 30:541,548 Carotenoid intermediate 4:676 Carotenoid monocations 30:546 theoretical calculations of 30:546 Carotenoid oxonium ions 30:530 Carotenoid phosphates 30:529 Carotenoid radical cations 30:524 Carotenoid sulphate 30:524,526,527 column chromatography of 30:527 field desorption MS of 30:527 1H-NMR spectra of 30:527 IR absorption of 30:527 negative mode FA of 30:527 partial synthesis of 30:527 reverse phase HPLC of 30:527 solubility properties of 30:527 sulphur analysis of 30:527 TLC of 30:527 Carotenoid-5,6-epoxides 30:530,531 colour test for 30:530 reaction mechanism of 30:531 Carotenoids 4:559;5:370,11,133-169, 150,73;7:321,318-321,329;9:559, 583 ;20:561,725,732,745 ;21:305; 23:178;24:216,533-540;25:44,237; 30:516-518,520,521-523,525,526,
151
537,541,516-518,520,521-523,525, 526,537,541 antioxidant action of 30:516 antioxidant properties of 30:525 application of 30:518 as antiviral compound 24:533-540 as protectors 30:522 by photoexcitation 30:537 cis-trans isomerisation of 30:541 de novo 30:518 electrochemical data of 30:537 from fungi 30:518 from phototropic bacteria 30:518 from phytoplankton 30:518 from termeric pigments 24:216 from yeasts 30:518 from [3-carotene 30:516 functions of 30:520 in light harvesting 30:521 in photoprotection 30:521,526 in photosynthesis 30:516,521 in xanthophyll cycle 30:521 mechanism of 30:522 role in camouflage 30:523 role in colour 30:523 role in phototaxis 30:523 role in phototropism 30:523 role in precursor 30:523 role in reproduction 30:523 role ofneoxanthin 30:523 use of cyclic voltammetry (CV) 30:537 with charged functional groups 30:526 Carotenols 6:150 carotenoid sulfates from 6:150 Carotenoprotein crustacyanin 30:518 Carotenoproteins 6:161,162,317;30:533 from crustacyanin 30:533 (+)-Carotol 14:356 Carotol 5:721,725,731,732,734,737 Carotol triol 5:730 Carp (Cyprinus carpio L.) 28:564;30:64 antitumor activity of 28:564 as diuretic 28:564;30:64 as tonic 30:64 for eye fatigue 28:564 use in eye fatigue 30:64
Carp extract 27:439 antitumor effect of 27:439 of gastrointestinal toxicity 27:439 of myelotoxicity 27:439 prevention of 27:439 Carp oil 28:566;30:55,56,64,65,68,69 antimetastatic activity of 30:56, 64,66 anti-tumor activity of 28:560; 30:64 components of 30:65 DHA from 30:65 effect on liver metastasis 30:55 effect on matrigel-induced angiogenesis 30:68 effect on tumor growth 30:55 EPA from 30:65 fatty acid from 30:65 in vivo 30:68 linoleic acid from 30:65 myristic acid from 30:65 oleic acid from 30:65 palmitic acid from 30:65 palmitoleic acid from 30:65 stearic acid from 30:65 use in tumor prevention 30:64 Carpalasionin 15:174 from Rabdosia rugosa 15:174 Carpesium divaricatum 29:89 Carpetimycins 4:434,135;12:135 Carpinus cordata 17:369 Carpinus sp. 17:369 Carpophilus hemipterus 29:282,292 ~-Carrageenan 30:412 1-Carrageenan 120 Carrageenan foot edema test 30:744 Carrageenan induced edema 25:46,220 inhibition of 25:46 Carrageenan induced paw edema 30:744 Carrageenans 30:399,402 mode of action of 30:402 7-Carrageenans 30:406 inhibitory effect of 30:406 K-Carrageenans 30:406 inhibitory effect of 30:406 Carrol conditions 6:122
152 Carrol rearrangement 10:58,60 Carrol-Claisen rearrangement 6:417 Carrot phytocystatin EIP 18 29:592 effects on chymopapain 29:592 effects on chymotrypsin, papain 29:592 effects on papain 29:592 Carssulaceae 21:737 Carthamus lanatus 14:450,451 eudesm-11-en-4-ols from 14:450 intermedeol from 14:450,451 Carthamus tinctorius 26:436 " Caruifolins (germacranolide sesquiterpene) 29:574 effects on HIV- 1 protease 29:574 Carum carvi L. 22:515 as anticonvulsant agent 22:515 Carvacrol 21:599;28:406,426 acaricidal properties of 28:406 as bioactive monoterpenoid 28:426 (R)-Carvane 25:858 Carveol 25:145,147,149;29:83 activity in RAS assay system 29:83 activity in mam-2 assay system 29:83 cis and trans 25:148,150 (+)-trans-Carvol 21:417 R-(+)-p- Carvomenthene 8:49 from R-(+)-limonene 8:49 Carvomenthenol 28:426 as bioactive monoterpenoid 28:426 D-Carvone 10:43,46,47 R-(-)-Carvone 16:155 S-(+)-Carvone 16:155 (+)-Carvone 7:6,732,608;14:517;20:69, 70;21:585 ;27:364 (-)-Carvone 6:66,67,549-551,157,156, 623 ;14:517 ;21:417,585 ;27:364 Carvone 7:114,115;16:123;21:595,590, 622;23:342;25:145-149;27:378; 28:426;29:83 activity in AM assay system 29:83 activity in GST assay system
29:83 activity in RAS assay system 29:83 as bioactive monoterpenoid 28:426 of optical isomers 27:378 D-Carvone epoxide 10:43 Horner-Emmons reaction of 10:43 Lythgoe aldehyde from 10:46 C-Aryl glycoside 10:370 stereoselective synthesis of 10:370 C-Arylglycals 10:344 by palladium catalyzed coupling 10:344 synthesis of 10:344 Caryophyllan 26:601,604 Caryophyllene 18:607;23:535,548; 25:125,168 [3-Caryophyllene 21:585,607;26:409, 413;30:607,723 structure of 30:723 Caryophyllene oxide 20:660;21:616; 23:800;26:397,402;29:91 ;30:607 activity in CRG assay system 29:91 from Salvia sclarea 20:660 (-)-Caryophylle" e-4,5-oxide 25:168 [3-Caryophylleh,z-oxide 21:581,585,580 Caryophyllenol-I 23:800 Caryophyllenol-II 23:800 Caryophyllose 26:600,601 Caryophyllus flos 29:590 Caryopteris clandonensis 4:612 Caryoptoside 7:470 Caryose 26:603,604 Casalpinia sappan 24:275 Casbene 8:16,17,25,181 Casearia sylvestris 24:280-282 Casein kinase 25:545 Casein/CFA 30:775 CVE-treated mice 30:776 immunization with 30:775 Cashew phenols 9:314,332334,338,341,368,372 Casimiroa edulis 22:515 for convulsions in children 22:516
153 Casomorphin 27:803 Casopongia 25:695 Caspase activity 28:320 of TNF-c~ 28:320 Caspase inhibitor 25:2-VAD 25:462 Cassia occidentalis L. for 22:516 Cassia sophera L. for 22:516 Catunaregam nilotica as 22:516 Khaya ivorensis A. as 22:524 Khaya senegalensis as 22:524 Newbouldia leavis as 22:527 Phyllanthus urinaria L. as 22:529 Phyllostachys heterocycla as 22:529 Psidium guyava L. as 22:530 Spilanthes mauritiana as 22:532 Thuja orientalis L. as 22:534 Uncaria rhyncophylla as 22:534 Vernonia chinensis as 22:535 Vemonia hildebrandtii as 22:535 Vitex negundo as 22:535 Ximenia americana L. as 22:535 Caspase-3 26:913 Caspase-3 protease 25:469 Cassaine 21:89 Cassameridine 2:436 Cassane 25:241 Cassane skeleton 19:395 Cassia corymbosa 26:1140 Cassia fistula 29:617 Cassia garrettiana 22:626;28:574 Cassia leptophylla 20:486,487 Cassia occidentalis L. 22:516,580,582 for convulsions in children 22:516 Cassia siamea 1:174,385 Cassia singueana 22:580 Cassia sophera L. 22:516 Cassia sp. 29:420 Cassia torosa 22:580,581 Cassiadine 21:139 Cassigarol A 28:575 effects on tumor growth 28:575 Cassine 18:741
Cassine balae (Elaeodendron balae) 5:743,744,747;7:149,150 Cassine glauca 23:652
Cassine transvaalensis 23:653 Cassinia uncata 24:122 Cassinic acid 23:674 Cassipourea gerrardii 7:192 Cassipourea gummiflura 7:192 Cassipourine 7:192 Cassumins A, B, and C 17:365-367 Cassumunin B 23:845 (+)-Cassythicine 16:509 Castanea crenata 19:246 Castanea sativa 29:592 effects on cathepsin B, chymopapain,ficin and papain 29:592 effects on trypsin 29:592 from chestnut Fagaceae seed 29:592 Castanea sp. 29:585 (+)-6-epi-Castanosperime 12:276,342344 absolute configuration of 12:342 from Alexa leiopetala 12:342 from Castanospermum australa 12:342 from L-gulonolactone 12:342 synthesis of 12:342-344 (+)-Castanosperime 12:337,338 6-acetamido-6-deoxycastanospermine from 12:345 absolute configuration of 12:332 allergic enecphalomyelitis activity of 12:332 asymmetric synthesis of 12:346 castanospermine N-oxide 12:352 chemoenzymatic synthesis of 12:337,338 enzyme-catalyzed acylation of 12:346 fromAlexa leiopetala 12:332 from Castanospermum australa 12:332 inhibitory activity of 12:332 insect antifeedant activity of 12:332 O-acyl derivatives of 12:346 plant growth regulating activity of 12:332 relative configuration of 12:332 stereoselective synthesis of
154 12:353,354 synthesis of 12:321,332-342 X-Ray crystallography of 12:332 Castanospermine 10:553,656;11:267; 27:253 absolute configuration of 10:553, 656 activity against human immunodeficiency virus 27:257 almond emulsin [3-glucosidase inhibitor of 10:553 as an anti-inflammatory agent 27:257 as anti-aids agent 11:267 as anti-hyperglycemic agent 27:257 Baeyer-Villiger oxidation of 10:557,558 biological activities of 27:255, 256 by chiral allylic alcohol 11:267 enantiospecific total synthesis of 10:553 from Alexa leidpetala 10:553; 11:267 from Castanospermum australe 10:553;11:267 ~-glucosidase inhibition by 7:12 [3-glucosidases inhibition by 7:12 glucosidase I inhibitor of 10:527 glucosidase II inhibitor of 10:527 glucosidase inhibitor of 11:267 glucosidases I,II by 7:11-16 glycosidase inhibition by 27:256 lysosomal c~-and [3-glucosidases inhibitor of 10:553 maltase by 7:12 stereoselective 11:267 stereoselective synthesis of 10:557,558 sucrase by 7:12 synthesis of 1:279-281;10:531, 533;11:267-271 Wittig-Horner condensation of 10:557,558
(-)-6-epi-Castanospermine 12:342 from D-gluconolactone 12:342 Castanospermine 22:183,30 6-epi-Castanospermine 27:517 (-)-8-epi-Castanospermine 7:12-15 6-epi-Castanosperrmne 7:12-15 from Castanospermum australe 7:12 from D-galactose 12:344 from L-gulonolactone 7:12 synthesis of 7:12;12:342 ot-glucosidases inhibition by 7:12 epi-Castanospermine 7:44 Castanospermine inhibitor 27:525 of c~,[3,-glucosidases 27:525 Castanospermine N-oxide 12:352 from (+)-castanospermine 12:352 Castanospermine stereomers 12:342 Castanospermum austale 12:342,343; 24:917;27:255 australine from 10:567 (+)-6-epi-castanosperime from 12:342,343 Castasteron 18:495,503,522 Castasterone 16:324 from Castanea sp. 16:668 from cyclasterol 16:324 synthesis of 16:322 Castela texana 23:299 Castela tortuosa 23:296 Castelanone 11:80,81 from chaparrin 11:80,81 Casticin 7:226,411-413;26:803 Castilleja tenuiflora 24:799,835,836; 25:713 iridoids of 24:835,836 Castor fiber 5:221 Casuareinondiol 17:371 Casuarianjunghuhniana 17:371 Casuarianaceae 17:371 CAT 25:674 Catabolism 25:332,348 of haemoglobin 25:332,348 Catabolite repression 25:313 Catalase 9:578 Catalpa ovata 29:733 6,3'-epi-Catalpol 7:484
155
Catalysts 4:302 Catalytic asymmetric aldol reaction 18:485 Catalytic deuteriation 9:476 Catalytic domain 30:830 of plasminogen activator (u-PA) 30:830 Catalytic epoxidation 11:431,432 Catalytic hydrogenation 6:425;19:77; 24:179,180;30:454 ofarabino isomer 30:454 of racemic ketoacid 24:181,182 with raney nickel 6:425 with rhodium 6:424 Catalytic hydrogenolysis 12:163,293; 22:277 Catalytic osmylation 11:431,432 Catalytic receptors 18:694 Catalytic reduction 19:76,91 Catalyzed rearrangement 16:512 Catechin 2:232,233,752,192,144; 21:618;22:317,351,429,609,645,663; 23:749,752,772;25:541,612;26:743, 744,748,757 ;28:41,273 ;29:579,581 (+)-catechin 28:273 effects on ACE 29:579 effects on collagenase 29:581 (-)-epicatechin 28:273 epigallocatechin 28:273 epicatechin-gallate 28:273 epigallocatechin-gallate 28:273 (+)-Catechin 7:192;21:128,498,520, 521-523,525,526,528;23:745,747; 25:612;26:359;27:416,746,774,893; 29:572 effects on HIV- 1 protease 29:572 oxidation of 27:774 c~-Catechin 7:192,193 Catechin 3-gallate (flavan-3-ol) 29:584 effects on proteasome CHYlike activity 29:584 Catechin derivatives 25:612 (+)-Catechin oligomers 27:774 Catechin-3-gallate 26:359 Catechin-based flavones 25:541 Catechol 14:678;21:235;25:613,662, 929 Catechol borane reduction 13:562
Catechol monomethyl ethers 5:449,451 Catechol oxidase 25:654 Catecholamine O-methyltransferase 21:17 Catecholamine-induced vasoconstriction 30:55,56,72,76 Angelica keiskei use in 30:72 effect ofchalcones 30:56 in rat aortic rings 30:56 inhibition by Angelica keiskei 30:55 Catecholamines 22:18,24;25:516; 26:1019 dopamine 25:520 epinephrine 25:520 norepinephrine 25:520 Catecholates 9:537 Catecholborane 11:43,44;12:157,158 Catechol-containing inhibitors 30:226 Catecholic berberines 26:822 pessione 26:822 Catechol-O-methyltrans ferase 5:449; 21:50,57,84;22:665,9 Catechols 5:447,456,318,325,328, 578,579 Caterpillar data 24:866 bioassay of 24:866 Catha edulis 22:427,436;23:652,660 Cathansterone 23 a-hydroxylation 25:421 Catharanthine 2:370373,381,383,385, 390,392,398,39,400,401,402 ;4: 31, 32; 13:663;14:809,810,820,821, 854-859,869-873 ;26:139;27:747,782 15',20'-anhydrovinblastine from 14:820,821,869-873 biosynthesis of 4:66 biosynthetic precursor of 4:31 catalytic hydrogenation of 14:809,810 coupling with vindoline 4:31,32 dihydrocatharanthine from 14:809,810 enzyme catalyzed coupling of 14:820,821 from Catharanthus roseus 13:663 from catharanthus roseus 14:855
156
vinblastine from 14:854-859 vincristine from 14:854-859 with vindoline 14:820,821 Catharanthine N-oxide 2:371,816,187; 3:857,859 (16 'S)-anhydrovinblastine from 14:857,859,816,817 Catharanthus roseus 19:246;22:9; 24:774 ;25:384 ;26:144 ;26:217,828, 829,753 ;27:744,780,782 alkaloid production of 2:370-391 alkaloids of 7:416 catharanthine from 13:663; 14:855 growth inhibitory activity of 7:416 leurosine from 14:860 vinblastine from 8:283;14:805 vincristine from 8:283;14:805 vindoline from 14:805;22:9 Catharine 2:370372,387,390-398 biosynthesis of 14:820,821 from anhydrovinblastine 14:812, 820,821,871 from leurosine 14:812 Catharinine 1:90,91 biosynthesis of 14:820,821 from anhydrovinblastine 14:820, 821,871 from 20'-deoxyleurosidine 14:812 synthesis of 14:847 Cathasterone 25:415,420 Cathedulin K 23:675 (+)-Cathenamine 13:490,491 Cathespin 26:913 Catheters 22:56 Cathinone 21:57,84;22:14 (-)-Cathinone 22:24;23:660 Cation channel 22:25 Cationic cyclization 14:793-795 (+)-chelamine by 14:793-795 (+)-chelidonine by 14:793-795 sanguinarine by 14:793-795 Cationic cyclopentannelation reactions 14:583-630 Cationic polyene polymerization 1:565
Cationic n-cyclization 12:287 of N-acyliminium ion 12:287 Cativic acid 25:254 Catunaregam nilotica 21:660;22:516 for convulsions 22:516 for convulsions in childrens 22:516 Caudatoside 26:719,720 Caudicifolin 9:288 X-ray crystal analysis of 9:288 Caudinoside A 7:278 from Parachaudina ransonetii 7:278 Caulerpa racemosa 18:689,714 Caulerpalean algae 18:688 Caulocyctis cephalornithos 15:386 Caulophyllum thalictroides 27:277 Cavernothiocyanate 25:858;28:662 spectral data of 28:662 (+)-Cavinton 18:331 Cavinton 19:89 Cayaponia tayuya 24:249 CBI cannabinoid receptor 30:196,198 affinity for 30:196 3-alkyl-5-arylimidazolidinediones as 30:198 CBz receptor 25:532,533;30:196 cannabinoid affinity for 30:196 N-Cbz-(S)-leucinal 12:489 Cbz-L-alanine 16:9 C-C bond formation 6:307-349 CC-1065 3:310,302,305 absolute stereochemistry 3:305 antitumor activity of 3:310,302 CDPI dimer 3:331,356-360 DNA sequence selectivity 3:304 formal synthesis of 1:180,184 isolation of 3:301 mechanism of action 3:303,304 molecular mechanic simulation 3:338-351 structure of 3:301 structure-activity relationship 3:338-351 synthesis of 3:331,356-460 synthesis of analogs 3:352 synthetic studies towards 3:301-383 total synthesis of 3:333-337
157 toxicology of 3:302 X-ray crystal structure 3:305 CC57BC-1 24:956,957 bioactive compounds from 24:956,957 CCK hormone 18:834 CCK-10,-12,-13 18:838 CCK-4,-5,-8,-18,-25,-33,-39, and -58 18:825 CCK-A antagonist 18:863 CCK-analog [Thr,Nle]-CCK-9 18:836 CCK-B antagonist 18:863 CCK-peptides 18:825,827,836,852,854, 857,859,860 CCK-radioligand 18:861 CC14-induced cytotoxicity 25:468 CC14-induced liver injury 25:466,469 CC14-induced liver injury model 25:471 CD correlation 6:137 of 19'-hexanoylfucoxanthin 6:137 of peridinin 6:137 with grasshopper ketones 6:137 CD Cotton effects 17:44 CD data 23:433 of agrimoniin 23:433 of casuarictin 23:433 of corilagin 23:433 of geraniin 23:433 ofnobotanin F 23:433 ofoenothein B 23:433 ofpedunculagin 23:433 ofrugosin D 23:433 of tellimagrandin I 23:433 oftellimagrandin II 23:433 CD excition chirality method 17:35,36, 51,53 CD procedure 9:27 absolute stereochemistry by 9:27 CD spectral analysis 6:539 of (+)-epiperiplanol-B benzoate 6:539 CD20 antigen 25:272 CD25 positive cells 25:454 CD4 positive cells 25:454 CD4 receptor 30:398 interaction of 30:398 CD4 T-lymphocytes 30:396
CD4-antigens 25:454 CD4-positive helper T cells 25:450 CD69 positive cells 25:454 CD71 positive cells 25:454 CD8 positive cytotoxic T lymphocytes 25:454 Cd-induced liver injury model 25:471 CDK2 activity 21:638 CDK2 tyrosine phosphorylation 21:136 CD18 antigens 25:454 cDNA clone encoding tomatinase 25:308 cDNA coding 25:61 cDNA copy of the HIV type-1 (H1V-1) genome 25:941 CDPK 25:542,546 inhibitors of 25:544 CD-spectroscopy 23:431 of ellagitannin oligomers 23:431 Ce (OAc)3-BFaOEt2 10:572 Ce (OAc)3-BF3OEt2 10:572 Cebocephaly 7:21;23:570 Cecropia juvenile hormone 3:271 synthesis of 3:271 Cecropia moths 22:82 squalamine from 22:82 Cecropin-B 27:806,807 Cecropins 22:83 Cedecea lapagei 28:404 Cedranolides 5:778-792 5-Cedranone 5:791-792 8,14-Cedranoxide 8:163-165 retrosynthesis of 8:163 synthesis of 8:163,164 total synthesis of 8:163-165 Cedrela tubiflora Bertoni 30:401 antiviral activity of 30:401 c~-Cedrene 15:270,609 A2-Cedrene 19:136 Cedrene 28:406 acaricidal property of 28:406 2-epi-~-Cedrene isoprenologue 15:270 Cedrene isoprenologues 15:269-271 13-Cedrene- 14-ol 8:164,165 Cedrol 5:782,788,790 Cedronia granatensis 23:301 Cedrus deodara 8:415;28:402,416
158
Cedrus odollam 22:516 for epilepsy 22:516 Cefotaxime 26:333 Cefoxitin 6:322 Cefriaxon 25:258 Ceftazidine 25:258 Ceiba pentandra 29:708 Celangulin 18:771;23:667 from Celastrus angulatus 18:771 Celangulin (II) 23:667 Celangulin (III) 667 Celangulin (IV) 23:667 Celapanol 18:744 Celaphanol A 29:91 activity in NFkB assay system 29:91 activity in NO assay system 29:91 Celasdin-B 30:643 NOESY of 30:643 HMBC of 30:643 structure of 30:644 Celasdine A 23:702 Celasdine B 23:702 Celasdine C 23:703 Celastolide 30:640 ~3C NMR spectra of 30:640 ~H spectra of 30:640 IR spectra of 30:640 structure of 30:640 Celastraceae 26:813 Celastraceae family 30:636,642,695 antifeedant activity of 30:695 genera of 30:636 insecticidal activity of 30:695 species of 30:636 triterpenes from 30:642 Celastroids 23:708 basic nucleus of 23:708 Celastrol 5:744-746,757,776;30:664 Celastrolides 30:642,693 against multidrug-resistant strain 30:694 against drug-sensitive strain N 30:694 from celastraceae family 30:642 Celastroloids 23:662 Celastrus angulatus 18:771;23:654,666 antifeedant activity of 23:666
insecticidal activity of 23:666 of spinach phenols 23:765 of tomato peel phenolics 23:766 Celastrus flagellaris 23:667 Celastrus gaumeri 30:691 in treatment of diarrhea 30:691 in treatment of snake bite 30:691 Celastrus gemmatus 23:667 Celastrus glaucophyllus 23:654 Celastrus hindsii 30:690 celasdin A from 30:690 celasdin B from 30:690 celasdin C from 30:690 maytenfolone-A from 30:690 Celastrus orbiculatus 29:88,91,708 Celastrus paniculata 5:743,744,747; 20:521 ;21:614;22:516;23:654 as antiepileptic 22:516 Celastrus pomonella 30:697 mortality of 30:697 Celastrus rosthornianus 23:667 Celastrus scandens 23:655;30:664 celastrol from 30:664 pristimerin from 30:664 Celastrus sp. 18:741,753;23:651 Celastrus stephanotifolius 23:672; 30:646 lupane caffeoyl esters from 30:646 Celecoxib 30:192 as COX-2 inhibitor 30:192 Celenamide 25:757 Celenamide E 25:778 Celery furocoumarins 744 Celestraceae 7:150 Celestrol 7:146,147,150-152 Cell adhesion 24:1085 inhibitors of 24:1085 Cell aggregation factors 24:1062 Cell apoptosis 26:925-926 role of nitric oxide in 26:925-926 Cell cultures 7:94-96 organogenesis of 7:94-96 totipotency of 7:94-96 Cell differenciation 26:926 role of nitric oxide in 26:926 Cell division protein kinases (CDKs) 25:526
159
Cell growth inhibitory agent 30:5 (+)-discodermolide as 30:5 Cell membrane stabilisation 30:523 due to Cs0-carotenoids 30:523 Cell proliferation 30:5,367,495 assessment of 30:495 in vivo inhibition of 30:5 inhibition by 16-desmethyl 30:5 inhibition by (x-thioanomers 30:5 inhibition by [3-thioanomers 30:5 inhibitor of 30:5 role of serotonin (5-HT) 30:367 Cell surface glycoprotein 26:950 Cellaria pilosa 17:95,101 Cellaria sp. 17:89,92 Cell-cell communication 30:523 Cell-free assays 29:40 abutasterone activity in 29:42 ajugalactone activity in 29:42 ajugasterone C activity in 29:42 as gel-shift assays 29:40 as radioligand displacement assays 29:40 cyasterone activity in 29:42 5-deoxykaladasterone activity in 29:42 ecdysone activity in 29:42 22-epi-ecdysone activity in 29:42 24- flur o- 20- hydroxyecdys one activity in 29:42 20-hydroxyecdysone activity in 29:42 inokosterone activity in 29:42 makisterone A activity in 29:42 polypodine B activity in 29:42 ponasterone A activity in 29:42 poststerone activity in 29:42 turkesterone activity in 29:42 Cell-mediated immunity 30:766,768, 773 against Listeria 30:768 macrophage activation in 30:773 role of cytotoxic T lymphocyte (CTL) 30:773 Cellobiohydrolases II 8:351 from Trichoderma reesei 8:351 Cellobiose analogues 7:64-66
c~-Cellobiose from 7:58 [3-Cellobioside 7:52 Cellobioside hydrolase II 7:58 [3-cellobiose from 7:58 [3-Cellobiosyl fluoride 7:58 Cello-oligosaccharides 7:33 Cellular activity 23:168,180 of secosterols 23:168,180 Cellular toxicity 27:876 ofokadaic acid 27:876 2-Cellulases 7:3,37,39,59,349,340, 344,352 Cellulasic 24:983-998 enzymatic activity 24:995-998 Cellulomonas dehydrogenans 7:69 decapenoxanthin from 7:69 Cellulose 5:32,275,276,268,14:268; 23:109 m-Cellulose 7:195 Cellulose 1,4-[3-cellobiosidase 7:3 DEAE-Cellulose chromatography 2:392,393,394 Celmer's model 23:86 Celorbicol 18:743 Celosai argentea 25:476 Celosian 25:476 Celtis cinnamomea 22:516 for convulsions 22:516 Celux pipens 19:481 ~-Cembra-2,7,11-triene-4,6-diol 29:100 activity in EBV assay system 29:100 activity in PKC assay system 29:100 activity in skin-1 assay system 29:100 activity in ODC assay system 29:100 [3-Cembra-2,7,11-triene-4,6-diol 29:100 activity in EBV assay system 29:100 activity in skin-1 assay system 29:100 activity in ODC assay system 29:100 Cembradiene hydroxy ether 15:253 Cembranes 15:253,22,28;23:172 Cembrane precursor 23:175
160
Cembranoid diterpenes 21:277 Cembranoids 8:15 anticancer activity of 8:15 Cembranolide 24:439 as FPTase inhibitor 24:439 as rHFPtase inhibitor 24:440 structures of 24:439 (7E)-Cembranolides 10:16 cis-Cembratriene 15:275 Cembratriene-4,6-diols (c~,[3-CBT) 3:4 cx,[3-CBT (Cembratriene-4,6-diols) 10:3,4 Cembrene 8:16,25 Cembrene A 5:701,702,220,221,255; 8:220;12:181 (-)Cembrene-A 5:701,702 3Z-Cembrene-A 8:221 Cembrenoids 23:176 Cembrolides 23:175 Cenarchaeum symbiosum 25:718 Cendranes 29:87 Centaur X3 7:202,203,221 Centaurea 29:580 Centaurea cyanus 22:679 Centaureidin 7:226;22:481;30:727,728 identification of 30:727 isolation of 30:727 structure of 30:728 Centella asiatica L. 21:674;22:516 asiaticoside from 21:674 Centipeda minima 26:808 Centipeda orbicularis 22:516 for epilepsy 22:516 Centraherin 29:89 activity in NFkB assay system 29:89 Central analgesic activity 30:200 in anilidopiperidines 30:200 Central nervous system 21:581 ;28:315; 30:194,370,384,799 cannabinoid receptors in 30:194 depressent activity on 21:581 effect of Crocus sativus 28:315 on central nervous system 21:581 opioid system in 30:799 parts of 30:370 TPH activity in 30:370
Central opioid receptors 30:816 intrinsic activity of 30:816 Centrifugal Liquid Chromatography (CLC) 24:137 Centrifugal partition chromatography (CPC) 25:207 Centrocerus clavulatum 26:478 (3R,7S)-Centrolobin 17:366 (3R,7R)-Centrolobin 17:367 Centrolobium paraense 17:367 Centrolobium robustum 17:367 Centrolobium sclerophyllum 17:367; 26:902 Centrolobium sp. 17:358,366 Centrolobium tomentosum 17:367 (-)-Centrolobol 17:358,361 (-)-(R)-Centrolobol 17:361 Centrolobol 17:367 Cephaelis ipecacuanha 21:97;26:144, 836 emetine from 21:97 Cephalodiscus gilchristi 18:875,876, 901,902 Cephalomannine 11:4,5,61 ;12:179,180; 20:81;25:245 Cephalosporin-C 11:211,212;22:247 biosynthesis of 11:211,212 from 5-(L-ot-aminoadipoyl)-Lcysteinyl-D-valine (LLD-ACV) 11:211,212 from penicillins 11:211,212 Cephalosporin P1 21:237 Cephalosporium acremonium 11:211, 619;22:263 Cephalosporium aphidicola 21:721; 24:197;25:153,155 aphidicolin from 22:234 Cephalosporium caerulens 5:613 Cephalotaxaceae 26:185 (+)-Cephalotaxine 18:319;19:141 Cephalotaxus alkaloids 24:294 cytotoxicity of 24:294 Cephalotaxus harrington var. drupacea 24:289,291 Cephalotaxus sp. 3:455,483,484;19:141 Cephalothin 6:322 Cephalothrix linearis 18:725 Cepharadione A and B 20:481 ;25:197 Cepharanthine 21:80
161
Cephotaxime 30:693 Ceramide 1-sulfates 28:621 as DNA topoisomerase I inhibitor 28:621 Cerastoma brevicaudatum 28:651 (methylthio) furodysinin from 28:651 dithiofurodysinin disulfide from 28:651 Ceratinamides A and B 25:620,784 Ceratiomyxa fruticulosa 29:237 Ceratitis capitata 5:223 2,5-dimethyl-3-ethyl-pyrazines of 5:223 Ceratocistis fimbriata 5:305,306,351; 23:355;25:485 Ceratocystis 25:129 Ceratocystis brunnea 5:306 Ceratocystis minor 15:385 Ceratocystis paradoxa 5:306,307 Ceratocystis sp. 5:296,305,309,325; 26:1127 Ceratocystis stenocerus 5:305 Ceratocystis ulmi 5:305 Ceratodictyon spongiosum 25:902; 28:683 cis, cis-ceratospongamide of 28:683
trans, trans-ceratospongamide of 28:683 Ceratonia siliqua 21:504;26:1139,1142 Ceratosoma brevicaudatum 25:815 Ceratozamia spinosa 26:1158 C-erbB-2-kinase 25:797,799,870,871 Cerbera mangmas 7:176 Cerbera odollum 7:195;22:516 Cerberalignan A 20:273 Cerbinal 16:302-304 antifungal activity of 16:302-304 from Cerbera manghas L. 16:302 synthesis of 16:302-304 Cercidothrix Bunge 27:444 Cercis siliquastrum 26:1145 Cercospora beticola 15:351;22:459 Cercospora taiwanensis 15:383 Cereale secale 9:328 Cerebellar dysfunciton 26:1130 as syndrome type-lA 26:1130
Cerebellar granule cells 25:268 role in apoptosis 25:268 Cerebellar white matter 30:375 hyperplasia of 30:375 Cerebral cortex 30:193,370,377 serotonergic innervations in 30:377 Cerebral grey matter 30:375 hyperplasia of 30:375 Cerebral thrombus 30:839 fibrinolytic agent in 30:839
Cerebrotendinous xanthomatosis 17:207 Cerebrum rudimentary 23:566 Ceric ammonium nitrate 4:322,323, 331,332;25:821 Ceric chloride 1:552 Ceridimine 5:123 Ceriops decentra 7:192 Ceriops sp. 7:176 Ceriops tagal 7:176,180,195 Cerium (III) chloride 14:753 Cerium ammonium nitrate (CAN) 14:780 Cerium carbanion 1:552 Cemilton 27:212 in treatment of benign prostatic hyperplasia 27:212 Ceroplasteric acid 1:563-564 (+)-Ceroplastol I 18:20-22 Cerotoma trifurcata 9:392 Cerulenin 5:600,609,613-615 Ceruloplasmin 22:9,327;26:1012,1016 Cervical carcinoma 25:268;30:405 Cesium fluoride 1:563,564 Cestode (tapeworm) 12:7 Ceterach officinarum 29:573,580 Cetraria islandica 5:309,310,322 Cetraria richardsonii 5:310,311 N-Cetyl-cysteine 26:993 Ceveratrum group 23:563 Ceylanicine 5:146,147 Ceylanine 5:147-149 (~-C-Glycosides 10:381 by condensation of methylallyl tri-n-butylstannane 10:381 by condensation with furan 10:377 by reaction of acylester 10:371
162
from pyridyl thioglycoside 10:382 from et-tri-n-butyltin glycoside 10:384 stereoselectivity of 10:371 with allyltrimethylsilane 10:371 [3-D-C-Glycosides 10:383,384 from 3,4,6-tri-O-t-butyldimethylsilyl-2-deoxy D-glucopy ranosyl phenylsulfone 10:383, 384 C-Glycosyl compounds 10:373,374 by catalytic siloxymethylation of O-acylglycosides 10:373,374 by reaction with HSi R3/CO/ Co2(CO)s 10:373,374 C-Glycosylarenes 10:380 by reaction of benzoylated Oalkyl glycosides 10:380 C-Glycosylation 10:387 of aromatic ring 10:387 ofheterocyclic ring 10:387 C-Glycosylcyanides 10:355 from acylated bromosugars 10:355 synthesis of 10:355 C-Glycosyl-oxirans 10:361 from acetobromoglucose 10:361 cGMP PDEs 25:523 cGMP-gated ion channel 25:541 cGMP-gated Na+channels 25:517,521 cGMPphosphodiesterase 25:521 cGMP-radioimmunoassay 26:938 CGP-41251 12:388 cyclic AMP-dependent protein kinase inbitor 12:388 $6 kinase inhibitor of 12:388 tyrosine specific protein kinase inhibitor of 12:388 CH3SOCH2 27:512 from dimethylsulphoxide 27:512 a-Chaconinase 25:305 Chaconine 23:575,584 c~-Chaconine 7:190-192,194,195;21:80; 25:300,305,311 ;26.'467,817, 868 Chactomellic acids 24:418-428 2D structure alignment of 24:421 FPP mimetics 24:420
structure-activity relationship of 24:426-428 structures of 24:419 synthesis of 24:421-426 Chaenorhabdtis 26:429 Chaetoglobocins 4:620 Chaetoglobosin D 13:108 Chaetoglobosins 13:108,150,355 Chaetomella acutiseta 21:194 chaetomellic acid A from 21:194 chaetomellic acid B from 21:194 Chaetomellic acid A 21:194 Chaetomin 21:220,240 Chaetomium 5:730,203 Chaetomium cochiliodes 25:168,170 Chaetomium globosum 21:211,220, 221,229;28:125 2-(buta- 1,3-dienyl)-3-hydroxy4(penta- 1,3-dienyl) tetrahydrofurane from 21:211 Chaetomium sp. 21:220,221;27:382 Chagas disease 2:293,302;24:818,819; 26:673,787 ;30:740 by Trypanosoma cruzi 30:740 treatment of 26:787 Chain elongation 4:199 of D-mannopyranose system 4:199 Chaksine 21:139 Chalcomoracin 17:465;28:210 biosynthesis of 17:465 from moraceous plants 28:210 Chalcones 7:427;13:450-452;22:432, 345,420;23:841 ;26:800;27:745,928 antiparasitic activity with 26:800 molluscicidal activity of 7:427 E-Chalcone 26:471 Chalcone derivatives 7:207 in Artemisia palustris 7:207 Chalcone isomerase 25:668 Chalcone reductase 25:653 Chalcone synthase 25:655 malonyl-CoA 25:655 Chalcone synthesis 21:742 Khan's method for 21:742 Chalcone-synthase 25:504 Chalogens 9:109-126 Chamaecaparis nootkatensis 23:341; 28:408
163
Chamaecyparis obtusa 25:246;28:234 Chamaecyparis pisifera Endle 24:206; 29:170 Chamaecyparis sp. 21:615 Chamaesaracha conioides 22:28 Chamberlin 12:445 Chamic acid 23:341,345 (+)-[3-Chamigradiene 6:63 Chamigrane 9:344,59 Chamigrane-type derivative 25:701 Chamigrane-type, halogenated 25:702 Chamigrenal 26:244 as PAF-induced inhibitor 26:244 Chamigrene precursor 6:30 Chaminic acid 23:341,345 Chamomila recutita 22:427 fl-D-glycosyl-7-apigenine from 22:427 luteolin from 22:427 quercetin from 22:427 Chamydosporol 13:543[3toxicity of 13:543 Chan-Brownbridge procedure in (-)-pseudopterosin-A synthesis 6:74,75 Chanoclavine I 11:199,200 Chaparrin 7:381,394,80,81 Chaparrinone 5:38-41,380-381,392, 395-396;23:301 ;26:816,817 Chara globularis 18:677 charamin from 18:677 3-azelidinol from 18:677 4-azoniaspiro [3,3] heptane-2,6diol from 18:677 Charamin 18:677 from Chara globularis 18:677 Charania lampas 15:58,88 Charatoxins 18:697 Charged carotenoid species 30:515 Charonia sauliae 7:306,724 Chartella papyracea 17:85,86,89,92, 692 Chartellamide A & B 17:86 Chartelline A,B & C 17:86 Chaulmoogric acid 8:140 Cheilantes 26:722 Cheimonophyllal 26:457 Cheimonophyllon A&D 26:457
Cheimonophylum candidissimus 26:456,457 (+)-Chelamidine 14:796 from berberine 14:796 synthesis of 14:796 (+)-Chelamine 14:793-795 from coptisine 14:793-795 stereochemistry of 14:793,794 synthesis of 14:793-795 through cationic cyclization 14:793-795 Chelaner antarcticus 6:436,445 pyrrolidine venom alkaloids in 6:436 pyrrolizidine alkaloids in 6:445 Chelate model 11:268,269 Chelating transition state models 12:167 c~-Chelation 11:234 ~-Chelation 11:234 Chelation 12:149,150 Chelation controlled 10:286 Chelation controlled aldol condensation 10:286 Chelation controlled Grignard reaction 1:266 Chelation directed addition 3:271 Chelation-controlled addition 14:50 Chelation-controlled alkylation reaction 30:12 Chelation-controlled reduction 30:11 Chelation-controlled Sakurai reaction 12:333 Chelelactam 27:167 Chelerythrine 14:773-775,796;21:69; 22:26,77 ;26:488;27:158,163,164, 172,863 biological activities of 27:178, 179 from berberine 14:773-775,796 from oxychelerythrine 14:774, 775 synthesis of 14:773-775,796 through enamide-aldehyde cyclization 14:774,775 Chelflutine 22:77 Chelidonieae 27:161 (+)-Chelidonine 14:793-795 biosynthesis of 14:770,771
164 from coptisine 14:793-795 synthesis of 14:793-795 through cationic cyclization 14:793-795 Chelidonine 21:96 Chelidonium majus 27:155,158,159, 162,168,169;29:592 Chelidonium majus L. 27:158 Cheliferoside 15:59 from Lathasterias nanimensis chelifera 15:59 Chelilutine 14:780,781;27:156-166,172 10-hydroxychelerythrine 27:156, 157 10-hydroxysanguinarine 27:156, 157 12-hydroxychelirubine 27:156, 157 biological activities of 27:178, 179 biological activities of 27:178, 179 chemical reactivity of 27:166 from 7-O-demethyl dihydro chelerythrine 14:780,781 isolation of 27:164-166 synthesis of 14:780,781 Chelirubine 14:777,778 biosynthesis of 14:779 from protoberberines 14:777,778 from sanguinarine 14:779 synthesis of 14:777,778 Chelynotus semperi 17:23;21:269; 25:893;28:639 Chemic acid 23:345 Chemical carcinogenesis studies 30:592 in epidermal cell culture 30:592 of BALB/c mice 30:592 Chemical classification 20:136-139 of withanolides 20:136-139 Chemical correlation 26:117 of strictosidine and vincoside 26:117 Chemical defence compounds 21:108 Chemical degradation 23:30; 27:191-196 of benzoxazinoid acetal glucosides 27:191-194 of low density lipoprotein
27:846 ofSAMM 2 23:30 Chemical ionisation (C.I.) 9:466,470, 477 Chemical manganese dioxide (CMD) 4:85 Chemical methods 26:552 of structural analysis 26:552 Chemical properties 27:336,507 of cyclopropane 27:336 ofpolysaccahride F-8 27:507 Chemical reactivity 27:156-166 of chelilutine 27:156-166 Chemical reactivity screening 29:647 colorization reactions of natural products in 29:647 high-performance thin-layer chromotography (HPTLC) in 29:647 Chemical synapses 21:8,9 Chemical synthesis 27:196,207-210 of benzoxazinoid acetal glucosides 27:191-194 of benzoxazione aglucones 27:190-191,195,196-207 Chemical transformation 26:101,102 of bakankosine 26:101,102 of secologanin 26:97,99 of sweroside 26:103,104 Chemical transformation methods 30:591 in vivo 30:591 role in chemopreventive activity 30:591 Chemical-induced edema 12:398 Chemical-induced neoplasia 30:311 solid tumor (sarcoma-180) as 30:311 Ehrlich ascites model as 30:311 juglone against 30:311 plumbagin against 30:311 Chemiluminescence 25:940 Chemoconvulsants 22:508 Chemo-differentiation therapy 30:498 of acute monocytic leukemia 30:498 Chemokines 25:535 Chemo-perception system of plant cell 25:394
165
Chemopreventive activity 30:591,597, 766 in mouse mammary organ culture model 30:591 in vitro 30:597 in vitro bioassays for 30:591 of Chlorella vulgaris 30:766 of isoquinoline alkaloids 30:597 of lignans 30:597 Chemopreventive agent 26:219 genkwanin as 26:219 (+)-lariciresinol as 26:219 sitoindoside II as 26:219 Chemopreventive efficacy 27:386 of limonene carcinogenesis 27:386 Chemoprophylaxis 26:674 Chemoselective epoxidation 14:366 Chemoselective hydroxylation 6:79 ofbicyclic triene 6:79 Chemoselective reduction 10:85;30:25 of unsaturated ester 30:25 with lithium tri -tertbutoxyaluminohydride 10:85 Chemosensitizers 30:595 antimalarial drugs as 30:595 Chemosy stematics 6:133-135 of acetylenic carotenoids 6:147 ofallenic carotenoids 6:133-135 Chemosystematic markers 6:155 acetylenic carotenoids 6:155 Chemotactic tripeptide 25:275 Chemotaxonomic markers 26:1128 Chemotaxonomy 27:369 Chemotherapeutic agent 30:5,330,742 atovaquone 30:330 for colon cancer 30:5 for multi-drug resistant cancers 30:5 for taxol-resistant breast cancer 30:5 Chemotherapeutic intervention 30:397 targets for 30:397 Chemotherapy 26:781,782,783 of malaria 26:781,782,783 Chemotherapy drug 27:436 antitumor activity of 27:436 Chenodeoxycholic acid 17:207 Chenopodium album 7:398
Chenopodium ambrosioides 20:12; 26:431
Chenopodium Chenopodium Chenopodium Chenopodium
anthelminticum 20:12 botrys 21:584 quinoe 9:402
spp. 28:392 Cherimolin 26:441,442 Chest pain 30:203 use of ginseng root in 30:203 Chewed garlic 23:465 Chichipegenin 27:44,45 structure of 27:45 Chida's synthesis 30:38-40 of (-)-pironetin 30:38-40 Childhood disintegrative disorder (CDD) 30:384,372 Chiliophyllin 27:559 Chilo suppressalis 24:715 ;29:25,29 ajugasterone B activity in 29:28 makisterone D activity in 29:28 shidasterone (stachysterone D) activity in 29:28 213,3{3,20R,22R,25-pentahydroxy14[3-methyl-5 [3-cholest-7,12dien-6-one activity in 29:28 Chilomonas paramecium 2:294 Chiloscyph-2,7,9-trione 20:473 Chiloscyph-2,7-dione 20:473 (+)-Chiloscypholone 18:624 Chiloscyphone 18:609;20:473 from Chiloscyphus polyanthos 18:609 Chiloscyphus polyanthos 2:278,279; 18:609 Chiloscyphus rivularis 20:472 Chimanine B&D 26:820,821 Chimeramycin 5:613,614 Chimeramycins A&B 5:614 Chinensinaphthol methyl ether 26:194 Chinese crude drug 28:202 sanggenon A from 28:202 sanggenon C from 28:202 sang-Bai-Pi as 28:202 Chinese medicinal plants 21:729 bioactive natural products from 21:729 Chinese mulberry tree 28:202 isoprenylated flavonoids from 28:202
166
Chippiine 5:128 Chiral 1,3-dioxane 14:480 Chiral 1,4-dihydropyridine 14:744 isonitramine from 14:744 Chiral 1-acylpyridinium salt 12:351 Chiral 2-amino alcohol 12:415,416 synthesis of 12:415,416 Chiral 4-hydroxyoxazolidin-2-ones 12:450 Chiral acetals 14:506,507 asymmetric cyclization of 14:506,507 asymmetric synthesis from 14:496-516 bromination of 14:505,506 diastereoselective 14:505,506 for asymmetric bromolactonizations 4:338,339 from (-)-(2S,3S)- 1,4-dimethoxy2,3-butanediol 14:496 from (2R,4R)-pentanediol 14:473 from (2S,4S)-pentanediol 14:481 from 1,3-diphenylpropane- 1,3diol 14:480 from C2-symmetric diols 14:469-516 from dialkyl tartarate 14:505,506 from perillene 14:506,507 nucleophilic additions of 4:330-332 preparation of 4:324 with methallylsilane 14:481 with trimethylsilyl cyanide 14:473 Chiral acetylenic acetals 14:471 chiral alkoxy-allenes from 14:471 with Grignard reagent 14:480 Chiral acrylates 8:416 Chiral acyclic ~-keto acetals 14:501 from (-)-(2R, 3R)-2,3-butanediol 14:501 LiA1H4-reduction of 14:501 Chiral alcohols 14:470 Chiral alkoxy-allenes 14:480 from chiral acetylenic acetals 14:480 synthesis of 14:480
Chiral alkyl (1,3-butadien-2-yl) methanols 14:474 Chiral allylboronates 11:423,424 synthesis of 11:423,424 Chiral allylic alcohols 4:160-161 Chiral amide bases 10:31-33 [2,3] Wittig ring contraction with 10:31-33 Chiral amines 14:496 from chiral imine 14:496 Chiral aryl Grignard reagents 14:508, 509 diastereoselective addition of 14:508,509 Chiral arylaldehyde acetal chromium tricarbonyl complexes 14:511 asymmetric metallation of 14:511 Chiral auxiliaries 4:327 acetals as 4:327 asymmetric induction with 4:327-345 binaphthyl diols as 4:335 by (R)-(+)-cx-methyl benzylamine 4:324 by 1-(-)-methyl ester 4:323 chiral diamides as 4:335 glycosides as 4:327 in asymmetric Diels-Alder reaction 4:345 in Diels-Alder reactions 4:334-336 oxazolines as 4:327,332,333 preparation of 12:416-418 prolines as 4:327 stereo-differentiating reactions 4:327 sugar as 4:334-336 thiazolidine derived 14:735 Chiral boron reagent 4:609 from B(OCH3)-(R,R)-(+) tartaric acid 4:609 in asymmetric Diels-Alder 4:609 Chiral building blocks 13:73-84;29:419 asymmetric synthesis of 14:551-581 from malonic acid derivatives 13:73-84 in synthesis of 3-piperidinol
167 alkaloids 29:419 6-membered lactam as 29:419 monofluorinated 13:81 preparation of 4:349-359,73-84 stereodivergent process for 29:419 via intramolecular Michael reaction 14:551-567 Chiral carbapenems 12:121 Chiral catalysts 17:479 Chiral chromatography 18:411 Chiral cyclized hemiacetal 14:487 from chiral vinyl ether 14:487 Chiral cycloalkanone acetal 14:486 chiral vinyl ether alcohols from 14:486 from (-)-(2R,4R)-2,4-pentane diol 14:486 Chiral cyclopropanation 14:401-405 of chiral pyrethroid analogues 14:401-405 of thujone 14:401-405 Chiral dienophiles 8:140 cycloaddition of 14:503 ct-hydroxcarboxylic acid derivatives 8:140 isoquinolinium salt with 14:503 Chiral dienyl ether alcohol 14:487,488 (+)-africanol from 14:487,488 cyclopropanation of 14:487,488 Chiral dioxane acetals 14:476 asymmetric nucleophilic cleavage of 14:476 diastereoselective cross-aldol reaction 14:472 from (2S,4S)-2,4-pentanediol 14:471 from (2R,4R)-pentanediol 14:477,478 with organometallic reagents 14:476 with Reformatsky reagents 14:477,478 Chiral enamine 14:553 asymmetric 14:553 intramolecular Michael reaction of 14:553
Chiral enol ethers 14:489 asymmetric 14:489 C-N bond formation 14:489 Chiral enone acetal 14:510 Chiral epoxidizing agent 4:172,173 diastereofacial selectivity of 4:172,173 chiral lactones 4:493 from c~,[3-acetylenic alcohols 4:493 from keto acids 4:493 preparation of 4:493 Chiral ester 14:552 Chiral fragments 6:282 ofamphotericine B 6:282 synthesis of 6:282 Chiral imine 12:161 [2+2] cycloaddition of 12:161 from ethyl (S)-lactate 12:161 addition of organometallic reagents 14:496 chiral amine from 14:496 Chiral imine acetal 14:497,498 with lithium enolate 14:497,498 Chiral inducer 1:73 Chiral induction 18:480 with Schoellkopfreagent 10:653, 655 Chiral isoquinolines 10:671 synthesis of 10:671 Chiral Lewis acids 8:140 Chiral molecules 21:580 Chiral monoterpenes 27:372 3-carene 27:372 Chiral monoterpenoids 27:361,381 antibacterial activity of 27:381 antifungal activity of 27:381 anti-neoplasmatic activity of 27:386 bioactivity of 27:361,377 isomerism of 27:361 Chiral N-acylated 2-oxazolone 12:419 2-amino alcohol synthon from 12:419 electrophilic addition of 12:419 from camphor-derived carboxylic acid 12:419 with bromine and phenyl selenyl
168
chloride 12:419 with DPPO• 12:419 Chiral N-glycosyl nitrones 1:370,371 Chiral nitroolefination 14:631-644 ofenolates 14:631-644 Chiral ortho ester 14:508 from diethyl (L)-tartrate 14:508 Chiral ortho ester vinyl ethers 14:503 Chiral oxazolines 4:333 Chiral piperidines 10:671 synthesis of 10:671 Chiral precursors 6:298,299 aspartic acid as 6:298,299 (S)-3-hydroxybutyrate a 6:300,301 (R)-methyl-p-tolylsulfoxide 6:301,302 Chiral pyrethroid analogues 14:398-405 from thujone 14:398-405 synthesis of 14:398-405 via chiral cyclopropanation 14:401-405 Chiral reduction 1:482 Chiral reproduction 4:346 Chiral sesquiterpenes 14:406-425 synthesis of 14:406-425 via Robinson annulation reaction 14:406-425 Chiral shift reagent 4:326 Chiral steroid analogues 14:431-444 synthesis of 14:431-444 Chiral steroidal acetal 14:481,482 from (2R,4R)-(-)-pentanediol 14:481,482 from (2S,4S)-(+)-pentanediol 14:481,482 with organometallic reagent 14:481,482 Chiral sulfamyloxaziridines 4:489 asymmetric oxidation with 4:489 oxidation of sulfides with 4:489 Chiral sulfoxides 10:671-685 to 3,4-dihydro-6,7-dimethoxyisoquinoline 10:679-685 Chiral sulfoximines 10:671-679 intramolecular addition to 10:671-679 to 3,4-dihydro-6,7-dimethoxyisoquinoline 10:679-685
Chiral sulfur reagents 10:671-689 asymmetric synthesis with 10:671-689 Chiral sulphoxide 14:747 (-)-sibirine from 14:747 Chiral synthesis 12:477 of amino acid 12:477 of 1-(a-hydroxyalkyl)- 1,2,3,4tetrahydroiso quinolines 12:450 ofbioactive natural products 13:84-99 of bioregulators 6:537-566 of semiochemicals 6:537-566 Chiral synthon 1:482;20:817-881 by selective redox reaction 20:817-881 with yeast 1:482 for 2-aminoalcohols 12:416-425 Chiral tartaric amides 4:338,339 trans-acetalization of 4:338,339 Chiral template effect 12:489,500 Chiral templates 14:267-281 Chiral tertiary alcohols 14:491,492 asymmetric synthesis of 14:491, 492 from chiral a-keto acetals 14:491,492 Chiral titanium complexes 4:489 asyrmnetric oxidation with 4:489 oxidation of sulfides with 4:489 Chiral vinyl ether alcohols 14:486 from chiral cycloalkanone acetals 14:486 synthesis of 14:486 Chiral vinyl halide 12:35,36 coupling reaction of 12:35,36 with chiral a-methyl-substituted aldehyde 12:35,36 Chiral vinyl sulfoxides 10:671-679 intramolecular addition to 10:671-679 Chiral vinyllithium compounds 12:35-62 addition reaction of 12:35-62 Chiral ylide 4:125 fromL-malic acid 4:125 Chiral a,[~-ethylenic acetals 14:479 from C2-synmletric diols 14:479
169
with phenyl or alkenyl copperBF3 reagents 14:479 Chiral ~,[3-unsaturated acetals 14:478, 479 from (R, R)-(+)-N, N, N', N'tetramethyl tartaric acid diamide 14:478,479 with organo-aluminum reagents 14:478,479 Chiral (x-aldoxime-ether acetal 14:496 organocerium reagents to 14:496 Chiral (x-amino acetals 14:483 Lewis acid-mediated reaction of 14:483 with silicon-containing nucleophiles 14:483 Chiral (x-keto acetals 14:491,492 chiral tertiary alcohol from 14:491,492 from (-)-(2R, 3R)-2,3-butanediol 14:491 from (-)-(2S,3S)- 1,4-dimethoxy2,3-butanediol 14:491 Chiral (x-methyl-substituted aldehyde 12:35,36 coupling reaction of 12:35,36 with chiral vinyl halide 12:35,36 Chira113-1actams 12:121 synthesis of 12:121 Chiral co-cyano alcohols 14:475 from achiral (x-methoxycycloalkanone oxime acetates 14:475 synthesis of 14:475 via Beckmann fragmentation reaction 14:475 Chiral-o-quinodimethanes 14:502,503 asymmetric intramolecular 14:502,503 Diels-Alder reaction of 14:502, 503 with C2-syrnmetric acetals 14:502,503 Chiriquitoxin 21:73 Chiro-inositol 7:9 (x-glucosidases inhibition by 7:9 [3-glucosidases inhibition by 7:9 invertase binding with 7:10
(+)-Chiro-inositol 7:37,38 from conduritol [3 epoxide 7:38 Chiron approach 17:211 Sharpless oxidation 17:211 Chironomus tentans 29:32 Chironomus tentans epithelial cell line 29:32 Chirons 14:179;24:3 Chiroptical properties 2:153-173 in natural product structure determination 2:153-173 Chirotopicity 7:5 Chitanase 5:289 Chitin 5:280,287,289,291 ;23:107, 109;27:402;30:95 alkaline hydrolysis of 30:95 from shell of crabs 27:402 Chitin synthetase 1:399 Chitinases 22:75 Chitinasic 24:999-1001 enzymatic activity 24:999-1001 Chitin-chitosan 30:95-100 effect on blood pressure 30:95 effect on body weight in mice 30:98 effect on fat excretion 30:97 effect on free fatty acid 30:100 effect on hepatic triacylglycerol 30:100 effect on liver weight 30:100 effect on lipase activity 30:96 effect on pancreatic lipase activity 30:95,96 effect on parametrial adipose tissue weight 30:99 effect on serum triacylglycerol 30:100 effect on total cholesterol 30:100 in mice 30:99,100 in vitro 30:95 inhibitory effects of 30:96 intestinal absorption of 30:95 Chitobiose derivative 6:398,404,413 Chitobiosidases 21:224 Chito-oligosaccharides 7:33 Chitosan 4:720,276;23:109;25:396; 27:402-404,436;28:560,563 anti-obesity action of 27:402,403
170
anti-tumor activity of 28:560 biological activity of 27:404 effects on doxorubicin-induced gastrointestinal toxicity 28:563 of myelotoxicity 27:436 preventive effects of 28:563 prevention of 27:436 structure of 27:403 Chitosan inhibitory effects 28:561 on gastrointestinal toxicity 28:561 on immunocompetent organ toxicity 28:561 on myelotoxicity of 5-FU 28:561 Chitosome 5:276 Chitranone 2:212-215,754,755 Chitin 25:396 Chlamydia 26:1134 Chlamydia trachomatis 13:183 Chlamydomonas reinhardtii 26:364 Chlamydosporol 13:543-545 c~-Chlamydosporol 13:543 toxicity of 13:543 Chlamys hastata 25:813;28:717 Chlidanthine 20:359 Chlonostachys cylindrospora 26:451 Chloramphenicol 25:757;29:310 against bacillary dysentery 29:311 bacteriostatic effects of 29:311 biological activity of 29:310 biosynthesis of 29:310 effects on A erobacter ganera 29:311 effects on Bacillus ganera 29:311 effects on Diplococcus ganera 29:311 effects on pneumonia viruses 29:311 effects on Proteus ganera 29:311 effects on rickettsiae 29:311 effects on Staphylococcus ganera 29:311 effects on Streptococcus ganera 29:311 effects on trachoma viruses 29:311
effects on veneral lymphogranuloma viruses 29:311 effects on Vibrio ganera 29:311 effects on viruses 29:311 Chlordiazepoxide 21:673 Chlorella 25:429;30:762,764,766,787 detoxicating enzyme activity of 30:766 effect on plasma rennin activity 30:787 hypotensive components in 30:787 uses of 30:762 Chlorella cell 30:783,765 GABA in 30:784 glutamic acid in 30:783 Chlorella diet 30:763 effects of 30:763 on fecal excretion 30:763 Chlorella effect 30:787 on plasma rennin activity 30:787 Chlorella emersonii 26:358 Chlorella kessleri 25:430 Chlorella protothecoides 30:766 role in detoxication 30:766 Chlorella vulgaris 25:430,431,450, 452,453,455 ;30:761,762,766,782 against microbial infection 30:782 antitumor activity of 25:452 effect on gluthathione Stransferase 30:765 effect on skin papillomas 30:762 effects on fecal excretion 30:762 host defensive study of 30:761 immune-active acidic glycoprotein from 25:455 immunological effect of 30:782 mechanism of 30:782 pharmacological study of 30:761 role in dioxin excretion 30:762 role on inhibition of cytochrome P-450 30:766 role on inhibition of malondialdehyde levels 30:766 topical application of 30:762 use in colorectal carcinomas 30:762
171 Chlorella vulgaris strain CK 22 (CVs) 25:429-433,436,437,440,447,450 antitumor immuno-activity of 25:432 anti-peptide ulcer effect of 25:430 host-mediated activity of 25:431 immunopotentiating effects 25:429 Chlorhexidine 26:402 Chlorinated cylindrol B~ 25:790 Chlorinated malyngamides K 25:788 Chlorinated PCDD 30:764 c~-Chlorinating reagent 6:310 of sulfoxides 6:310 Chlorination 6:310,340;19:61 trans -5-Chloro- 1-menthen-8-ol 11:307, 308 3'-Chloro-2'hydroxy arguticinine 5:207 3-Chloro-2-hydroxy-arguticinin 9:66 1-Chloro-35-dimethoxy benzene 13:360 3-Chloro-3-deoxy-allo-derivative 14:163 2-Chloro-4-methylphenol 21:165 2-Chloro- 5-nitropyridine 12:309 (23 R)-6a-Chloro- 5 ~, 17c~-dihydroxy12[3-methoxy-1-oxo- 12,22-epoxyergosta-2,24-diene-23,26-olides 20:242 Chloro-8-hydroxy- 1,2-methylene-3[(1E,3E,5E)-5-methyl- 1,3,5heptatrienyl)] octahydroindolizidine 12:301 (1S,2R,3S,7S,8S,8aR)-7-from indolizomycin 12:301 5-Chloro-8-quinolyl 4:286 3'-Chloro-abscisic acid 27:353 Chloroacetoxylation 16:443 Pd(II)-catalysed 16:443 9-Chloroacronycin 20:792 (c~-Chloroalkyl) boronic esters 11:409, 410 synthesis of 11:409,410 Chloroamine 11:307,308 N-Chloroamines 6:437 from N-chlorosuccinimide 6:437 Hoffmann-Loeffier photocyclization of 6:437
Chlorobactene 7:339,361-363 2-(3-Chlorobenzoyloxy)- 1-(2-methoxyphenyl)-2-(4-ethoxyphenyl) ethanol 30:223 structure of 30:223 (Z)-3-Chloro-butenoate 20:830 (Z)-3-Chloro-cinnamate 20:830 (cz-Chlorocrotyl) boronic ester 11:424 (methoxycrotyl) boronic ester from 11:424 from allylic alcohol 11:424 c~-Chlorocyclopentene carboxylate esters 8:225 Favorskii rearrangement of 8:225 3-Chlorodehydroleucodin 29:90 activity in NFkB assay system 29:90 7-Chlorodehydronoraporphine 16:516 6-Chloro-D-tryptophan 15:35 2-Chloroethylphosphonic acid 25:509 Chloroformate ester-induced reaction 6:477,486 ring destruction by 6:477,486 Chlorogenic acid 15:36;22:167,346, 645,663;23:740,744,749,753;25:663, 655,657,667,919-921,930,932-935, 937-940,942-947 ;26:695 antioxidative properties of 25:919,930,935 (+)-Chlorogenic acid 27:421 biological activity of 27:421 3-Chloroguaiazulene 14:331 Chlorohydrins 1:451 Chloroissoclimide 25:270 Chloroklotzchin 7:214 from Artemisia klotzchiana 7:214 p-Chloromercuribenzoate 27:736 Chloromercuric method 4:233 in synthesis of 6-deoxynucleosides 4:233 (Chloromethyl) zinc reagent 14:490 2-Chloromethyl-4-nitrophenylphosphorodichloridate 8:73 2-Chloromethylbenzoate 5:827,828 Chloromethylene dimethylforminium chloride 3:212 6-Chloromethylsalicylate 5:828
172 Chloroorcinols 25:757 m-Chloroperbenzoic acid 2:90-103 Chloroperoxidase 25:767 3-Chloroperoxybenzoic acid 22:203 o-Chlorophenyl group 4:269 p-(Chlorophenyl) sulfinyl acetate 21:380 bis-2-Chlorophenylhydrazones 12:379 Chlorophora tinctoria 22:360;29:582, 573,580,585 Chlorophyceae 6:134,147 Chlorophylls 7:98;20:760-762 Chlorophyllin 30:765 with dioxins 30:765 Chlorophylls a,b,c 20:728 Chlorophyta 27:735 3-Chloroplumbagin 2:212,214,754 Chloropromazine 12:387 (S)-(R)-Z-Chloropropionic acid 6:386 with methyl 2-acetamido-4,6-Obenzylid-ene-2-deoxy-~x-Dglucopyranoside 6:386 Chloropseudomonas ethylica 7:363 Chloropuupehenone 15:299 Chloropyridine 25:792 6-Chloropyridine-3-carboxylate 20:864 to 3-hydroxymethyl-6-chloropyridine 20:864 Chloroquine 20:517,518;22:147;23:301; 25:335,336,337,343,344,345,346, 347,348,349,352,360;26:1030,1035, 1037,1038,1063,1065;30:596 Chondroitin sulfate 30:101-103,105, 107,108,109,397 D-glucuronic acid 30:101 D-N-acetylgalactosamine 30:101 Chloroquine diphosphate 7:393 Chloroquine Fe(III) PPIX 25:346 Chloroquine potentiating antiplasmodial activity 30:597 in vivo 30:597 of laudanosine 30:597 Chloroquine sensitivity 30:595 in resistant Plasmodium species 30:595 Chloroquine-enhancing activity 26:1065 Chloroquine-enhancing effectiveness 30:596
of alkaloids 30:596 Chloroquine-pyrollidinyl 25:344 Chloroquine-resistant parasites 25:352 Chlorosampangine 23:6 N-Chlorosuccinimide 6:310;12:487 DMSO reaction with 6:310 monochlorinated sulfoxide from 6:310 N-chloroamines from 6:437 Chlorosulfolipid 28:655 stereochemistry of 28:655 Chlorosulfonyl isocyanate 4:475,477; 22:275 cycloaddition with 4:475,477
1-acetoxy-2-methylbutadiene
with 12:150,151 [2+2] cycloaddition of 4:475; 12:150,151 Chlorotrimethylsilane 19:445
Chloro-tris-( triphen yphosphine )
rhodium decarbonylation with 5:802 Chlorowithanolides 20:223 Chlorphenamine 26:401 Chlorproguanit-dapsone 26:783 4-Chlorugenic acid 23:757 Chocolate spot disease 4:590 Cholecalciferol (vitamin D3) 9:509-528 Cholecystokinin 18:824;24:910-913 as putative satiety factor 24:910 effect on contraction 24:910-913 effect on relaxation 24:910-913 related peptides 24:910-913 Cholecystokinin effect 27:799,800 Cholelithiasis 27:378 Cholelithiasis therapy 27:378,382 Cholera toxin 25:521,538 Choleretic 22:346;24:799 Achyrocline satureioides as 22:346 biological activity 24:799 Choleretic activity 23:356;26:399,400, 414 of isofraxidine 23:356 5,c~-Cho 1est- 14-dne- 3 [3,6c~,24-trio1 7:288 Cholest-5-en-3[3-ol (cholesterol) 9:5,37, 447,449;9:454,461,462
173 Cholest-5-ene-24-0ne-313,7oc-diol 20:477 Cholest-5-ene-3ot,4[3,21-triol 3,21disulphate 15:98 from Ophiura sarsi 15:98 Cholest-5-ene-3 [3,7ot,diol- 1-oxo 20:707 from Salvia glutinosa 20:707 Cholest-7-enyl linolenate 9:470 5 oc-Cholesta-9(11),24(25)-dien-3 ~, 6or 20,22-tetraol aglycone 15:49 5cx-Cholestan-3-one 2:168 octant rule in 2:168 5cc-Cholestan-3 [~,6cc,8,15o~, 16[3,25hexaol 15:77 from Protoreaster nodosus 15:77 5ot-Cholestane 20:248 Cholestane glycoside 21:636 5ot-Cholestane-3[3,5,6[3,9-tetrol 23:159 5 [3-Cholestane-3 cc,4a, 11 [3,12[3,21pentaol 3,21-disulphate 15:96 5 [3-Cholestane-3 oc,4c~,1113,21-tetraol 3,21-di-sulphate 15:96 (25R) 5 [3-Cholestane-3cx,6[3,15ct, 16[3,26pentaol 15:75 (25R) 5c~-Cholestane-3[3,5,6[3,15c~,1613 26-hexaol 15:75 (24S) 5c~-Cholestane-3 f3,6ct,8,15 [3,24pentaol-aglycone 15:61,68 Cholestanepentols 17:214 5a/513Cholestanols 9:454 steryl palmitates of 9:454 Cholestanyl palmitate 9:454 Cholesterol (cholest-5-en-3[3-ol) 9:5,37, 447,449,454,461,462,464,470 Cholesterol acyltransferase 25:722,797 Cholesterol biosynthesis 23:480 inhibition of 23:480 Cholesterol oxides 24:351-398 biological activities of 24:353-376 biosynthesis of 24:358-360 effect on activity of HMGR 24:373-376 role in coronary heart disease 24:376-381 Cholesterol synthesis inhibition 25:525
Cholesterol variation number (CVN) 24:351,368,369 Cholesterol-(7-dehydrocholesterin) 9:510,512,521 Cholesteryl 3,4,6,-tri-O-acetyl-[3-Dglucopyranoside 8:363,365,366 Cholesteryl acetate 9:464,465 Cholesteryl arachidonte 9:454,459, 461,467 Cholesteryl butyrate 9:464,465 Cholesteryl caproate 9:464,465 Cholesteryl elaidate 9:457 Cholesteryl esters 9:450,453,457,462, 466-478 Cholesteryl laurate 9:465 Cholesteryl linoleate 9:456,461,464,467 Cholesteryl myristate 9:460,465 Cholesteryl oleate 9:456,457,464,467 Cholesteryl palmitate 9:454-456,459, 461,464,465,467, 472,477 Cholesteryl palmitoelaidate 9:457 Cholesteryl palmitoleate 9:456,457,467 Cholesteryl stearate 9:456,461,465 Choline 5:752; 24:1007,1008;25:475, 476 occurrences of 24:1007,1008 Choline sulfate 24:1007,1008 occurrence of 24:1007,1008 Cholinergic activity 21:736 Cholinergic antagonists 21:102,109 Cholinergic decumbenines 21:733 Cholinergic receptor 21:51 ;22:16 Cholinergic transmission 22:15 Cholinesterase 7:18 Cholinesterase inhibitor 21:748,749 Cholinestrase inhibitor huperzine A Cholistane-3fl,5 t~,6p-triols 24:352 cytotoxicity effect of 24:352 Chondocurine 25:472,476 Chondodendron autumnale 25:476 Chondodendrum tomentosum 13:631 Chondostoreium purpureum 21:196 Chondria armata 17:21 ;26:479 Chondria baileyana 26:479 Chondria californica 25:842 Chondria oppositiclada 6:40 cycloeudesmol from 6:40 Chondria sp. 26:488 Chondria tenuissima 25:249
174 Chondriamide A&B 26:488 Chondrilla sp. 18:718 Chondrillin 5:353,354,718;23:211 Chondrococcus hornemanni 5:343 Chondroitin sulfate 30:101-103,105, 107,108,109,397 effect on 2-monooleoylglycerol uptake 30:103 effect on adipose cells diameter 30:109 effect on body weight 30:107 effect on fatty acid uptake 30:101 effect on glucose uptake 30:101 effect on hepatic triacylglycerol 30:109
effect on liver 30:108 effect on palmitic acid absorption 30:103 effect on pancreatic lipase activity 30:101,102 effect on parametrial adipose tissue 30:108 effect on rat plasma triacylglycerol levels 30:105 in HIV therapy 30:397 in mice 30:107,108 in vitro 30:101,103 inhibitory action of 30:101 Chondromyces sp. 25:730 Chondrosia collectrix 18:719 Chonistoneura fumiferana 26:876 Chorda 26:1121 Chordata 21:3 Choriaster granulatus 7:299 Choriocarcinoma 14:805 vinblastine for 14:805 vincristine for 14:805 Chorisia speciosa 26:1157 Chorismate mutase 11:188,189 prephenic acid from 11:188,189 Chorismic acid 11:187 anthranilic acid from 11:187 from 5-enolpyruvylshikimate 3phosphate 11:187,188 phenylalanine from 11:188 tyrosine from 11:188 Choristoneura fumiferana 22:388
6-Choro-9-(3-deoxy-[3-D-xylohexopyranosyl) adenine 4:232 Christofin 26:659 Chromaggin granules 25:536 Chroman 1:644,645 enantioselective synthesis of 1:644,645 Chromanes 4:391 from isoprene 4:391 from phenols 4:394 in prenylation methods 4:394-396 synthesis of 4:374 Chromanones 9:450 Chromatiaceae 7:361 Chromatogaphic analysis 9:450-453 by adsorption chromatrography 9:450-453 by gas chromatography 9:453-460 ofsteryl esters 9:447-486 Chromatogaster scutellaris 6:455-458 Chromatographic analysis 21:535 Chromatographic methods 21:507,525 Chromatographic techniques 30:591 fractionation 30:591 Chromazonarol 15:291,298 ent-Chromazonarol 15:291,299 Chromenes 2:126,368,369,372,373, 376,409,410;13:356,358 Chromenes 7:409,410;20:282;23:342 Chromis chromis 21:364 Chromium (II) reagents 3:81 Chromobacteria 21:298 Chromodoris cavae 9:4,13 Chromodoris elisabethina 28:650 icthyotoxic latrunculin A from 28:650 Chromodoris funarea 17:9,10 Chromodoris lachii 17:13 Chromodoris macfarlandi 17:11 Chromodoris maridadilus 6:69 Chromodoris norrisi 17:12 Chromodoris sp. 17:12,14 Chromodorolide A 9:4;17:13 Chromodorolide B 17:13 Chromodris hamitoni 25:735
175
Chromogenic assay 30:834 of chromogenic substrate 30:834 specificity of 30:834 Chromogenic substrates 7:53 Chromomycins 4:245;17:37 Chromomycin A3 3:173 Chromones 9:113-116;17:574;22:475; 24:499-503 as antiviral compound 24:499-503 Chromone alkaloids 21:123-153 biological activity of 21:123 Chromonocoumarins 7:415 Chromophore 30:534 polarisation of 30:534 Chromophoric oligopeptides 30:835 role in assay 30:835 Chromophoric procedure 30:834,835 role in assay 30:835 Chromosome 30:379 Chromosome exchange 27:304 Chromosome mutation test 27:303 epi-8-Chromozonarol 5:437 antimicrobial activity of 5:437 Chromozym TH 30:840 Chronic diabetes complication 30:697 cataracts in 30:697 peripheral neuropathy in 30:697 retinopathy in 30:697 Chronic experiment 27:313 Chronic inflammation alleviation 24:887-895 by medicinal plants 24:888-895 by neolignan 24:888-890 Chronic leukemia 26:925 Chronic pain model 30:203 activity of ginseng in 30:203 Chronic painful inflammatory diseases 30:206 pro-inflammatory substances in 30:206 Chronic rheumatoid arthritis 30:204 monodesmodides in 30:204 treatment of 30:204 use ofhederaginin 30:204 Chronic toxicity studies 27:308 Chronic viral hepatitis 25:463 Chryosplenoside A 5:682 Chrysamin 27:551
Chrysanolide 27:559 Chrysanthellin 15:209 Chrysanthellin B 15:210
Chrysanthemum cinerarifolium 28:384 pesticide properties of 28:383 secondary metabolites from 28:384 Chrysanthemumfrutescens 9:317 Chrysanthemum golden 20:246 Chrysanthemum mortifolium 22:122; 29:586-588 effects on CHY 29:586 Chrysanthemum parthenium 27:376 Chrysanthemum sp. 7:427 trans-Chrysanthemyl alcohol 7:100,101 Chrysanthemyl alcohol 7:126 cis-Chrysanthenol 9:530 Chrysanthenum coronarium 25:944 cis-Chrysanthenyl acetate 9:530,536 Chrysartemin B 7:235 Chrysazine 25:543,544 Chrysentunone 27:592 Chrysin 26:746,762 Chrysin (5,7-dihydroxyflavone) 29:572, 577 effects on aminopeptidase N 29:577 effects on HIV- 1 protease 29:572 Chrysocephalum ambiguum 25:251 Chrysochromulina species 6:135 Chrysoeriol 7:226;23:742;26:746 Chrysoeriol-7-O-p-coumaroyl glucoside 5:623 Chrysomma sinensis 5:837 hemoglobin components of 5:837 Chrysomycin 10:347 Chrysophanic acid 22:609,617,618; 23:537 Chrysophanoic acid 25:543 Chrysophanol 22:610;23:537,797; 26:637 Chrysophyceae 6:134,135 Chrysoplenium pseudofauriei 5:678 Chrysospermins 26:482 Chrysosplenium americanum 5:682 Chrysospleniumflagelliferum 5:682 Chrysosplenium grayanum 5:682
176 Chrysosplenol-D 7:413 antimicrobial activity of 7:413 Chrysosplenoside E 5:682 Chrysosplin 5:682 Chugaev reaction 4:45 Chukrasia tabularis 9:105 Chymacyparis taiwanesis 29:698 et-Chymotrypsin 2:35 Chymotrypsin 13:56,519,536,537; 30:830,831,837 homologous sequences of 30:831 Leu-X cleavage site of 30:837 Phe-X cleavage site of 30:837 Trp-X cleavage site of 30:837 Tyr-X cleavage site of 30:837 Culmoriuns 13:519,536,537 from Fusarium culmorum 13:536 synergistic effects 13:536 toxicity of 13:536 Chytridiomycetes 9:202 Chytridiomycota 22:246 Chytrids 22:246 Cibarian 27:522 Cicer arietinum 18:719;25:93;26:1268, 1288 Cichoriin 12:145 inhibitor of dehydropeptidase (DHP-1) 12:145 Cichorin 26:314 CIDMS/MS 19:643 Cidofovir 24:486,487 as anti-viral agent 24:486,487 Cieplak's theory 29:127 in sesquiterpenoids drimane-type synthesis 29:127 Ciguatoxins 21:300;25:732,733 Cilastatin 4:432 Cimetidine 25:612 Cimicifuga 25:180;29:582 Cimicifuga dahurica 22:516 Cimicifuga racemosa 27:277 Cimicifugic acid A (phenylpropanoid ester) 29:582 effects on collagenase 29:582 Cimifuga sp. 27:395 Cinachyra sp. 19:581 Cinachyrella alloclada sp. 26:67
Cinachyrolide A 19:580;25:759 13C-INADEQUATE 9:143-146 Cinchomeronic anhydride 6:510,511 Cinchona 21:488;22:146;516;26:835, 836 Cinchona alkaloids 7:444,62 Cinchona ledgeriana 26."144 Cinchona officinalis 25:476 Cinchona robusta 30:344 suspension culture of 30:344 Cinchona succiruba 26:779,780,820 antimalarial activity of 26:779 Cinchonamine 22:147 Cinchonidine 21:96,97,102,108,109; 22:146;26:836 1,8-Cineole 9:530,536;15:225,227; 21:595,621 Cineole 21:595,599,615 1,8-Cineole 25:140;29:83 activity in TNF assay system 29:83 Cinerin I 27:588 Cinerin II 27:588 Cinnabarin 26:1012 Cinnabarinic acid 26:967,1020 Cinnamaldehyde 21:621,622 trans-Cinnamaldehyde 27:16,33 structure of 27:33 Cinnamate 4-hydroxylase (C4H) 23:337 Cinnamate 4-hydroxylase 5:467,468; 25:653,660 Cinnamates 9:530,536 Cinnamic acids 5:459,467-470,473,479; 20:271 ;23:337,744,779;25:652,653, 925;28:261 caffeic (3,4-dihydroxycinnamic) acid as 28:261 (E)-Cinnamic acid 5:467 Cinnamolide 2:287,288,414 (+)-Cinnamolide 6:28 (+)-polygodial from 6:28 Cinnamomm osmophloeum 15:29 Cinnamomum camphora 22:516; 25:140,156 ;26:1039 ;28:419 as anticonvulsant 22:516 for hysteria 22:516 for epilepsy 22:516
177 Cinnamomum cassia 22:427 epicatechol from 22:427 epicatechol-O-glucoside from 22:427 Cinnamomumjaponicum 28:419 Cinnamomum osmopholeum 27:16 trans-cinnamaldehyde from 27:16 Cinnamomum philippinense 26:240,249 cinnamophilin from 26:240,249 meso-dihydroguaiaretic acid from 26:240 Cinnamomum sieboldii Meisner 15:33; 27:18,35 Cinnamtannin B- 1 from 27:18,35 Cinnamtannin D- 1 from 27:18,35 Cinnamomum sp. 24:275;29:588 Cinnamon bark 28:259 gallic acid from 28:259 salicylic acid from 28:259 syringic acid from 28:259 Cinnamonin 25:395 Cinnamonium camphora 18:558 (-)-dimethylmatairesinol from 18:558 Cinnamonum camphora 21:621 ;27:377 Cinnamonum zeyIanicum 27:377 Cinnamophilin 26:240 as PAF-induced inhibitor 26:240 Cinnamophilin 26:240,266,267 10-Cinnamoyl baccatin III 11:61 Cinnamoyl CoA 25:655 Cinnamoyl ester of crassin 8:15 antileukemic activity of 8:15 Cinnamoyl-CoA reductase 5:470 Cinnamoylcocaine 22:722 6N-Cinnamoyl- [3-naltrexamine (CNX) 30:812 molecular model of 30:812 Cinnamtannin 1 27:18,35,36 structure of 27:36 Cinnamtannin B-1 15:33 Cinnamtannin D-1 15:33;27:18,35,36 structure of 27:36 Cinnamyl alcohol dehdrogenase 5:470; 27:763
Cinnamyl alcohols 5:459,463,467, 469-471,473,474,495,497 ;27:760 polymerization of 27:760 Cinnzeylanine 26:853 Cinnzeylanol 26:850 Cinnzeylanone 26:850,853 Ciocalypta sp. 17:16;21:349,355 Ciona intestinalis 5:405,408,249 Ciona savignyi 25:784 Circadian activity 30:369 abnormalities of 30:369 effect on anorexia 30:369 effect on bipolar disorder 30:369 effect on bulimia 30:369 effect on obsessive compulsive disorder 30:369 effect on panic disorder 30:369 effect on schizophrenia 30:369 effect on seasonal affective disorder 30:369 effect on unipolar depression 30:369 Circular dichroic power 17:48 Circular dichroism 2:153,159-61,165, 166,169-173,226,227,137,140, 149,264,390,539,542;15:193,194; 423-438;22:374;26:550,551 ;30:584, 586 of (7R,8S,7'R,8'R)-(+)-7'-acetyl5 '-metho xyp icrop o doph yllin 30:586 of tetrahydrobenzylisoquinolines 30:584 Circular dichroism method (octant rule) 14:743 Circular dichroism spectroscopy 21:403 Circularly polarized light 2:154 Cirrhosis 30:406 Cirsilinol 7:226 Cirsiliol 30:727 structure of 30:727 Cirsimaritin 7:226;30:726,727,748 antispasmodic activity of 30:748 structure of 30:726 Cirsitiol 20:712 from Salvia montbretii 20:712 Cirsiumjaponicum 26:436 Cis and trans-deethyleburnamonines 25:19
178
Cis decalin-tetrahydrofuranyl kalihinol 25:855 Cis-5-hydroxy-4(4'hydroxy-3 '-methoxyphenyl)-4-2"-imidazoyl)-l,2,3trithiane 25:837 Cis-cis-ceratospongamide 25:904,905 Cis-deethylburnamonine 25:6 Cis-deethyldihydroeburnamenine 25:6 Cis-pentacin 22:285,299;23:349 Cisplatin 21:136;26:213;28:559;30:56 cancer chemotherapy drug 30:56 for cancer chemotherapy 28:559 side effects of 30:56 Cissampelos pareira 29:578 Cissua integrifolia 22:517 for epilepsy 22:517 Cistaceae 25:249,252,253 Cistanche deserticola 25:468,476 Cistrus hirusutum 19:246 Cistus clusii 25:250 Cistus creticus 25:246,249,250,252, 255,256,257,266 Cistus creticus ssp. erioocephatus 25:259 essential oils of 25:259 Cistus incanas ssp. creticus 25:258,266 Cistus ladaniferus 25:252 Cistus laurifolius 25:250 Cistus palinhae 25:250 Cistus spp. 29:581 Cistus symphylifolius 25:250 essential oils of 25:255 Citbrasine 13:350 from Citrus sinensis 13:350 Citeromyces matritensis 5:283 Citeromyces sp. 5:280 Citorellamine 25:837 Citpressine I 13:350 from Citrus depressa 13:350 Citpressine II 13:350 from Citrus grandis 13:350 Citracridone I,II 13:348,349 from Citrus depressa 13:348,349 Citral 13:332;20:5;21:595;25:132, 133,136,137,143;29:83 activity in skin-1 assay system 29:83 activity in TPA assay system 29:83
Citramalic acid 8:305 Citranaxanthin 20:606,607,757 Citranellae 25:132,140 Citraurin 20:757-759[~Citreorosein 22:609,610 (-)-Citreoviridin 10:439 Citreoviridine 18:176 Citric acid 7:180;21:192 in mangrove plants 7:180 Citric acid cycle 9:554;21:302,317 Citrobacter 12:63 Citrobacter freundii 26:402 Citrol 25:136,137,140 ~-Citromycinone 14:14 T-Citromycinone 14:8-10 synthesis of 14:8-10 Citronellal 8:47;25:128 S-Citronellal 17:610 (R)-(+)-Citronellal 19:215 R-(+)-Citronellal 8:43-46,57,258,266 S-Citronellate 15:229 (-)-Citronellene 17:605 R-(+)-Citronellic acid 16:344 Citronellic acid 21:589;25:133,136; 26:86 (+)-Citronellol 1:451 ;2:167,168,17,605 (S)-(-)-Citronellol 11:343,344,367; 16:192 (3R)-(+)-Citronellol 13:122,123 (R)-Citronellol 18:26;19:43 Citronellol 7:105,125;21:587,589,590; 25:132,133,136,137,140;28:426 as bioactive monoterpenoid 28:426 Citronellyl acetate 25:136 Citropten 18:979 L-Citrulline 26:931 Citrullus colocynthis 5:750;20:13; 22:517 as antiepileptic agent 22:517 Citrullus vulgaris 29:614 Citrus auranhtium ssp. amara 27:372375,377 petitgrain oil from 27:372-375, 377 Citrus aurantium 15:5;22:517;25:476; 27:17,377;29:573
179
neohesperidin dihydrochalcone from 27:17 Citrus buxifolia 13:350 atalfoline from 13:350 Citrus decumana L. 13:348,349;22:517 Citrus depressa 13:348 citracridones I,II from 13:348 citpressine I from 13:348 Citrus flavonoids 26:744 Citrus genus 27:377 Citrus grandis 13:348,349;22:517 baiyumine A from 13:348,349 baiyumine B from 13:350 butanine from 13:350 citpressin II from 13:350 grandisines I,II from 13:350 grandisinine from 13:350 honyumine from 13:348,349 prenyl-citpressine from 13:350 Citrusjunos 13:348,349 junosidine from 13:348,349 Citrus latifolia 27:372,377 Citrus limon 23:747;25:594;27:375,377 Citrus maxima 22:517 for epilepsy 22:517 for convulsive cough 22:517 Citrus natsudaidai 13:350;27:17,375 natsucitrines I,II from 13:350 Citrus oils 27:372 Citrus paradisi 14:450;23:747 eudesm-11-en-4-ols from 14:450 (+)-intermedeol from 14:450 naringin dihydrochalcone from 27:17 Citrus peel oils 25:145 Citrus reticulata 23:747;27:375;29:573 Citrus sinensis 13:348,350;23:747; 27:375 citbrasine from 13:350 citrusinines I,II from 13:348,350 Citrus sp. 5:651 ;25:128,266,267 Citrus unshiu 18:682 Citrusin B 20:697 Citrusinines I,II 13:348,350 from Citrus sinensis 13:348,350 Civet acid 1:637,638 enantioselective synthesis of 1:637,638
Civetone 8:223,224 acyloin condensation of 8:224 from Viverra civetta 8:219 Wittig reaction of 8:223,224 Ciwujianosides 15:191 Cladinose 13:155,156,158,159,162 L-Cladinose nucleosides 4:256 Cladobotrin 26:449 Cladobotryum rubrobrunnescens (Hyphomycetes) 26:449 Cladobotryum varium 26:449 Cladonia alpestris 5:310,313 Cladonia confusa 5:310,313 Cladonia crispata 5:310 Cladonia mitis 5:310 Cladonia rangiferina 5:310 Cladonia sp. 5:310 Cladonia squamosa 5:310 Cladophora fascicularis 5:367 Cladosporin 11:193;15:382,385-387; 23:343,348 Cladosporium cladosporiodes 11:193; 15:386,193;22:627;23:343,535; 26:553 Cladosporium coccodes 25:305 Cladosporium colocasiae 26:1091,1093 Cladosporium cucumerinum 7:406,409, 411,413 ;15:64,415,421,433 ;21:189, 257,266,275,277,281,283,284,662; 23:347 ;25:776;26:333,673 Cladosporium fulvum 25:302,308,398, 399,400 Cladosporium herbarum 20:245;2:475; 5:302 Cladosporium phlei 21:189 Cladosporium sp. 5:301,325,328,370; 25:145;26:1128 Cladosporium sphaerospermum 26:228 Cladosporium suaveolens 13:309-311, 313,315 Cladosporium wemeckii 5:301 Cladosporum herbanum 7:119 Cladrastis lutea 5:678,683 Claisen condensation 1:49,99,100,174, 243,410;11:114;19:35;20:740; 26:1237 of dicarboxylic acid derivatives 11:114
180
with acetoacetate dianion 11:114 Claisen cyclization 9:341 Claisen disconnection 19:228 Claisen ester enolate rearrangement 10:339 Claisen orthoester rearrangement 26:72 Claisen reaction 6:36 in poitediol synthesis 6:36 Claisen rearrangement 1:43,45,78,91, 172,173,180,181,230,243,251,457, 459,471,563 ;8:180;11:471 ;13:29,30, 135,142,358,417,437,438,443,613; 16:260,340,439,471,623,627,703, 712;19:229;20:66,67 ;24:47,756,758 [3,3]-Claisen rearrangement 10:416-426 applications of 10:416-426 asymmetric quaternization with 10:426-428 carboxylic acid anhydride variation of 4:375 Eschenmoser modification 3:230 in (+)-9-isocyanopupukeanane synthesis 6:82,83 in (+)-africanol synthesis 6:5 in (+)-sinularene synthesis 6:78, 79 in lactone synthesis 3:252-255 indolo [2,3-a] quinolizidines by 14:722-724 internal asymmetric induction 3:234 Ireland modification 3:77,228 of 1,5-anhydro-4,6-O-benzylidene-D-ribo-hex- 1-enitol 10:420 ofallyl ester 14:738 of allyl phenyl ethers 4:368 of carbohydrate derivatives 10:416-426 of carbohydrates 3:226 of chiral allylic alcohols 10:418 of cis 2,5-disubstituted dihydrofuran 10:423,424 of dihydropyran derivative 10:425 of E (3-hydroxy- 1-propenyl)- ~D-glucopyranose tetra acetate
10:422 ofN,O-ketene acetals 3:232 of oxygen substituted systems 3:237-248 of silyl ketene acetals 422,423 of vinyl ether derivative 10:420 of vinyl ketene acetals 10:234, 235 of xanthones 4:368,370-372 ortholactone procedure 3:236 regioselectivity of 4:368,368 Clarithromycin 13:164,183;25:617; 25:617 Clary sage oil 25:252 Class III peroxidase 27:737 Classical cannabinoids 30:195,198 structure-activity relationships of 30:198 Classical Nazarov reaction 14:612 Classification 6:546;28:281 ;30:198,560 by sporulation 6:546 of cannabinoid ligand 30:198 of ellagitannin oligomers 28:281 of ellagitannins 28:281 of fungi 6:546 of gallotannins 28:281 of galloylated proanthocyanidins 28:281 of macroline -related alkaloids 13:384-396 of proanthocyanidins 28:281 of prodelphinidins 28:281 of Rabdosia diterpenoids 15:112 of Strychnos alkaloids 1:32 of tannins 28:281 Clatha palustris 7:427 Clathramides 25:757,777 Clathria pyramida 6:351 ;28:715 Clathria sp. 28:702 Clathridine 17:18 Clathridine B 17:18 Clathrina clathrus 25:870 Clathsterol 28:702 against HIV- 1 reverse transcriptase (RT) 28:702 Clausantalene intermediate 4:675 Clausarin 4:374,375 synthesis of 4:374,375
181 Clausena anisata 22:517 as anticonvulsant 22:517 Clausena harmandiana 9:400 Clausena heptaphylla 2:118 Clausena indica 2:118 Clausena pentaphylla 2:118 Clavalanine 16:708 Clavaric acid 24:440 inhibition rHFPTase 24:440 structures of 24:440 Clavelina cylindrica 25:793,859;28:644 cylindricine F from 28:644 genistic acid 28:259 Clavelina lepadiformis 29:426 Clavelina picta 10:249;29:426 Clavepictines A,B 10:249 Claviceps 21:91,488 Claviceps eurotium 9:203 Claviceps fusiformis 5:278 Claviceps purpurea 13:631 Claviceps sp. 5:278;11:200 Clavicipitales 9:203 Clavosine 27:878,879 Clavukerin A 21:292 Clavularia inflata 6:77 (+)- 12-acetoxysinularene from 6:77 Clavulones 19:551 Cleavage ofolefins 1:445 with t-BuOOHg/HsIO6 1:445 with Mo (CO)6 1:445 Cleavamine-type alkaloids 5:103 capuronine 5:103 (+)-20R- 15,20-dihydrocleavamine 5:103 14S,20R-velbanamine 5:103 Cleislopholis staudtii 22:400 Cleistanthane skeleton 19:395 Cleistanthus collinus 26:204 cleistanthin A&B from 26:204 Cleistopholis patens 2:340;22:400; 23:4,341 Clematis hexapetala 19:125 Clematis sinensis 20:539,540 Clementine 23:747 Clemmensen reduction 12:240,279,697, 698 ;15:197,198 ;24:205 Clemmensen-type deoxygenation 19:18 (+)-Clemeolide 18:28-32
Cleomane 23:489 Cleome cileata 22:517 Cleome icosandra 18:28;23:487 Cleome viscosa 18:28 Cleomeolide 23:488,491 transformation of 23:488,491 synthesis of 23:488,491 Cleomiscosin A 5:5;7:377 Clerodane 25:241 Clerodane cajucarinolide 29:100 activity in TLO assay system 29:100 Clerodane diterpenes 24:280-282; 30:748 principles of spasmolytic drugs 30:748 structure of 30:748 neo-Clerodane diterpenoids 23:592 neo-Clerodanes 23:601 13C-NMR data of 23:604 lH-NMR data of 23:604 structures of 23:603 3~-H-neo-Clerodanes 23:607 13C-NMR data of 23:607 ~H-NMR data of 23:607 Clerodane-type diterpene 2:280 CisClerodendron inerme 20:539,540 Clerodendron wildii 21:662 Clerodendrum uncinatum 7:408,417, 423; 23:343 Climacostol 30:140,162 synthesis of 30:140 Clinical chemoprevention trials 30:592 Clinical development 30:5 for colon cancer 30:5 for multi-drug resistant cancers 30:5 for ovarian cancer 30:5 for taxol-resistant breast cancer 30:5 Clinical studies 30:842 of thrombolytic agents 30:842 Clinical trials 21:750,754 ofBtg A 21:754 ofHup A 21:748-750 Clinical usage 21:138 of flavopiridol 21:138 C-linked glycosyl acetylenes 10:358 from glycosylhalides 10:358
182
Cliona celata 5:411 Cliona chilensis 25:778 Clionamide 5:411 Clitocybe acromelalga 19:163;26:479 Clitocybe geotropa 18:813,814 Clitocybe nebularis 18:813,814 Clitocybe subilludens ( Omphalotus subilludens) 29:296 biosynthesis in 29:296 Clivia miniata 20:351 ;26:619,620 Clivonine 26:620 Clofazimine 2:424 Clomipramine 22:672 Clonal expansion 26:921 of antigen-specific T 26:921 Cloned mammalian adenylylcyclases 27:825 Clonidine 25:530 Cloning 7:114-117 Clonogenic assays 21:259 Closantel 26:440 Clostridium 13:303 Clostridium difficile 5:601 Clostridium formicoaceticum 20:821, 824,861-862,867,869,870,871, 873-879,881 Clostridium kluyveri 20:821,824,831, 834 Clostridium perfringens 5:601,71,81, 86,87;16:108;25:925 Clostridium tetanomorphim 9:598,601; 20:821,824,861-863,867,869,870, 871 Clostridium tyrobutyricum 20:821,824, 829,830,834-839,863,873-877; 25:147 Clotting disease 30:839 fibrinolytic agent in 30:839 Clove buds 28:259 protocatechuic acid in 28:259 syringic acid in 28:259 Clusia nemorosa 22:659 Clusia plukenetii 22:660 Clusia portlandiana 22:659 Clusia rosea 22:659 Clusioidea 30:604 CMB 4:368,369,372,373 CMTP 21:416
CMV infection 30:405 chemotherapy of 30:405 CNBr-induced reaction 6:472-474,476, 477,484,486,488,489,491,492,495, 496 Cnemidocarpa bicornuta 25:765 Cnestis ferruginea 22:517 Cnidaria 21:3,272 Cnidaria 23:153;28:646 corals among 28:646 gorgonians among 28:646 hydrozoans among 28:646 ellyfish among 28:646 living species of 28:646 sea anemones among 28:646 soft corals among 28:646 13C-NMR 5:533,534 incremental effects of 9:275-280 of ~-pipitzol benzoate 5:787 of (+)- 1-acetoxypinoresinol 5:533,534 of (+)- 1-fraxiresinol 5:535 of (+)- 1-hydroxypinoresinol 5:534 of (+)-epi-pinoresinol 5:526 of (+)-pinoresinol 5:526 of 10-demethoxykopsidasinine 5:52,54 of 11-O-methylcaesalpin 5:24 of 13-epi- 11-O-methylcaesalpine 5:24 of 2'-hydroxyflavone 5:4 of 2'-methoxyflavone 5:14 of 4-hydroxy-sapriparaquinone 5:36 of 6-isocedrol 5:789 of acteoside 5:507 of alloaristoteline 11:314 of aquillochin diacetate 5:9 of arguticinin 5:203 of argutinin 5:203 of aristolasicone (aristotelin- 19one) 11:314 of aristoteline 11:314 of artemisinin 5:24 of berberine 5:42,44 of bruceantin 5:39 of cadabicine methyl ether 5:210 of caratuberside A 5:212,213
183
of caratuberside B 5:213 of cedranolides 5:785 of cedrene 5:789 of colchicine 5:47-49 of cyanocycline A 10:106,107 of decitol 4:183 of dendropanoxide derivatives 2:102 of denticulatin 5:21,212 of eupatorenone 5:30 of flavone 5:14 of forsythiaside 5:509 of galactomannan 5:303 of ginamallene 5:369,370 of glucan 5:311 ofgualacm A 5:200 ofgualacln B 5:202 of gualanln A2 5:198 of gualanm B 5:199 of gualanln C 5:199 of gualanln E 5:199 ofheptitol 4:177 of holacanthone 5:39,40 of hortensin 5:15 of indicoside A 5:214 of indocoside B 5:215 of isoaquillochindiacetate 5:9 ofisobrucein A 5:39,40 of isopeduncularine 11:284 ofjuliflorinin 5:211 of L-arabinitol 4:181,182 of lareantin 5:10 of L-glycero-D-mannoheptose 4:219 of lycopene 7:342 of manzamine A 5:349-351 ofmanzamine B 5:349,350 ofmanzamine C 5:349,350 ofmanzamine F 5:351 of matairesinol 5:506 of nirurine 5:51 ofnortrachelogenin 5:531 of nortrachelogenin methyl ether 5:531 of odonticinin 5:209 of oligomers of L-glycero-Dmannohptose 4:219 ofonnamide A 5:365 of perezinone derivatives
5:74-78 of permethylated (meso)-pentitols 4:182 ofpicrasin B 5:39 of pinnatifidone 5:216,217 of pluchecinin 5:205 ofpolysaecharides 5:297,298 ofprionitin 5:31-32 of pullulan 5:288,289 of quinocarcin 10:118 of quinocarcinol 10:118 ofsaframycin A-D,F,G 10:82 of salvinolon 5:33-35 of sanguinarine 5:45 of saprorthoquinone 5:37 of staurosporine 5:61 of staurosporine aglycone 5:61 of suspensaside 5:509,510 ofzeaxanthin 7:342,345,346,351 of (x-chaparrinone 5:39,40 of (z-pipitzol 5:786,787 of [3-hydroxyacteoside 5:509 of [3-1umicolchicine 5:47-49 of x-lumicolchicine 5:47-49 CNS-activity 21:4 CNS-depressant activity 21:582 C-Nucleosides 10:337,338,355,358, 388-394 CoA ligas 25:653,666 Coagulation 26:240-245 role ofplatelet activating factor (PAF) 26:240-245 Co-artemether (lumefantrine/ benflumetol-artemether 26:783 Cobalamin 9:605,606 Cobalamin cofactor 11:210 Cobalt-stablized carbocations 3:83,84 in macrocyclization 3:83,84 coculolidene 3:456,488 synthesis of 3:477,478,488,489 Cobinamide 9:605,606 Cobyrininc acid 9:591,592,597-601, 603,605,606 Cocaethylene 22:7 (+)-Cocaine 22:7,19 (-)-Cocaine 22:7,19,722,723 Cocaine 13:631;21:84,488;26:820 as psychodelic drug 26:820
184
Cocarcinogen 1:547 Coccidiodomycosis 22:60 Coccidioides immitis 22:57 Coccidiomycosis 2:422 Coccinelline 6:447 from tetrahydropyridinium salts 6:447 Cocculus sermentosus 22:517 for epilepsy 22:517 for nocturnal epilepsy 22:517 Cocculus sp. 3:456,478 Cocculus trilobus 3:488 Cochineal 20:729,734,768-771 Cochliobolus lunatus 25:318 Cochliobolus miyabeanus 23:133; 26:460 Cochliophilin A 22:458,460,495 Cochlioquinone A 26:460 Cochlodinium polykrikoides 30:400,408 anti-influenza activity of 30:408 (R)Coclaurin 20:292 Coclaurine 24:887 effect as neuromuscular blocker 24:887 Codeine 13:631;18:47,74,87,91;21:52, 488;22:9,10,24 Codeine-6-glucuronide 22:10 Codeinone 22:10 Codium arabium 25:704 Codium dwarkense 25:725 Codium latum 26:1138 Codonocarpine 9:73 Codonopsis 13:660 Coelenterata 19:549;21:272 Coenenchyme 21:272 Coenzyme A 11:191 Coenzyme A thioester 11:197 coenzyme B ~2-dependent rearrangement 11:197 Coetsoidin A 15:137,145,154,171 Coetsoidin B 15:117,124,131,171 Coetsoidin C 15:137,145,154,171 Coetsoidin D 15:137,145,154,171 Coetsoidin E 15:137,145,154,171 Coetsoidin F 15:138,146,155,171 Coetsoidin G 15:138,146,155,171 Coffea arabica 29:578 Coffea sp. 21:502 Coffee bean 2:116
Coffein 20:6 (-)-trans-Cognac lactone 14:272,273 from levoglucosenone 14:272, 273 synthesis of 14:272,273 Cognitive functions 30:368 role of raphe nuclei in 30:368 Coix lachryma 27:193,212;29:599 Colaphellus loweringi 18:771 Colaptes auantus 5:836 11-epi-Colartin 7:213,232 Colchicine 3:287-299,5,179; 5:4649,798,799;12:179;21:98,109;22:8, 32,471 ;24:269;29:364,357 (-)-(aR,7,S)-colchicine as 29:357 (+)-(aR,7,S)-colchicine as 29:357 allocolchicinoid synthesis from 29:364 as antimitotic agents 29:357 as tubulin assembly inhibitor 29:357 discovery of 29:357 in gout treatment 29:357 NMR of 29:358 SAR of 29:357 X-ray structures cf 29:358 (7S)-Colchicine 3:287-299;13:652 Colchicum autumnale 5:46;25:473; 29:356,358 hepatop,.,tective effect of 25:472 serum ALT activity of 25.473 Colchicum kesselringii 29:356 Colchicum luteum 22:517 for epilepsy 22:517 Colchicum ritchii 29:358 Colchinol analogue 29:378 allocolchicinoids total synthesis of 29:378 Cold press extraction 21:574 Colebrookea oppositifolia 22:517 for epilepsy 22:517 Coleomycetes 9:203 Coleoptera 22:371;26:851 Coleosol 25:252 Colestane 25:49 Coleus amboinicus 22:517 Coleus aromaticus 22:517 for convulsive affections 22:517 for epileptic affections 22:517
185
Coleus forskohlii 19:137;25:252,256, 261,958 forskoline from 13:659 Coleus sativus 25:956 Coleus sp. 7:96,118 Coley's toxin 28:519 anti-tumor activity of 28:519 Collagen 30:594 platelet aggregation induced by 30:594 Collectotrichum coccodes 25:307 Collectotrichum lagenarium 16:302 Colletotrichum dematium 9:230,238, 239 Colletotrichum gloeosporiodes sp. Jussiaea 9:288,229,231-235, 238-241 Colletotrichum gloeosporioides sp. aeschynomene 9:230,238,239 Colletotrichum gloeosporioides (Glomerella cingulaa) 9:228,230, 232,238-240 Colletotrichum graminicola 9:230,238, 239 Colletotrichum heterostrophus 22:267 Colletotrichum lagenarium 12:400; 22:266 Colletotrichum lindemuthianum 9:230, 239 Colletotrichum malvalum 9:230,231, 238,239 Colletotrichum sp. 9:228,230,239,247 Collidine 6:385,396,399,400 S-Collidine 6:549,550 Collins allylic oxidation 6:27 in (-)-dictyolene synthesis 6:27 Collins oxidation 1:16,83,84,210,312, 313,315,316;6:16;11:83,84 ;19:320, 334,467 ;22:277 ;24:7 Collins reagent 6:115,350,317,335; 16:16;22:206,222 Collins-Wege intermediate 6:78,79 in (+)-sinularene synthesis 6:78,79 Collinusin 24:769,770 synthesis of 24:769,770 Collisella limatula 17:26 Collision activation 2:4 Collision induced fragmentation 2:43
Collisional activated decomposition spectrum (CAD) 5:634 Collisional activation (CA) spectra 5:633 Collision-induced decomposition (CID) 9:468,489,494,496 Collision-induced dissociation (CID) 18:195;19:643 Colneleic acid 9:569,570 COLOC 9:147,151,152,268,274,287, 515 COLOC spectrum 24:280 of casearin A 24:280 Colocynthis vulgaris 5:743,744,750 Colon 26 carcinoma 19:609 Colon cancer 23:293;30:5 clinical development for 30:5 chemotherapeutic agent for 30:5 Colon-38 tumor cells 25:761 Coloradocin 17:284,286,304-306 Colorectal carcinomas 30:762 in rat model 30:762 induction by 1,2-dimethylhydrazine (DMH) 30:762 use of Chlorella vulgaris for 30:762 Colorenone 21:285 Colorimetric assays 21:508,511,523, 551 Colourants 20:719-783 Colubrina asiatica 21:673 jujubogenin-3-O-glycosides from 21:673 Colubrinol 23:70 Columbamine 11:201-204,656;21:84 Columbianadin 23:363 Comantheria briareus 7:266 Comantheria perplexa 7:266;28:719 polyketide sulfates of 7:266 Comanthula pectinata 7:266 polyketide sulfates of 7:266 Comanthus parvicirrus 7:266 Comatula pectinata 28:719 anthraquinones from 28:719 Combined effects 27:438;28:562 of chitosan 28:562 of 5-fluorouracil 27:438 of 5-FU 28:562 Combretaceae 23:405;25:180
186
Combretastatin 22:471 Combretastatin A-4 24:406 antimitotic inhibitory activity of 24:406 as tubulin transferase 24:408,409 Combretum 25:180,183;26:1157 Combretum glutinosum 28:424 Combretum micranthum 28:424 Commiphora incisa 22:117 Commiphora molmol 24:119 Commiphora mukul 5:695,700,701 cis-Communic acid 28:456 trans-Communic acid 28:456 Comoramide A 25:883 Comoramide B 25:883 (+)-Compactin 11:335,336 biological activity of 11:335, 336 Compactin 22:251 Compactinervine 1:36 COMPARE 17:495 Competitive inhibitors 7:40,56,69,70 Comphor derivatives 4:628,632 synthesis from camphor- 10sulphonic acid 4:628,632 Comphor-2,8-homoenol 4:638,641,655 Complestatin 10:629,630,667 Complete freunds adjuvant (CFA) 19:702 Complex I inhibitor 28:436,437 annonaceous acetogenins as 28:437 capsaicin as 28:436,437 deguelin as 28:436 monotetrahydrofuranic derivatives 28:437 piericidin A as 28:436 rotenolone as 28:436 rotenone as 28:436 tephrosin as 28:436 Complex imidazole alkaloids 21:68 Complex indole alkaloids 21:79,84 Complex lipids 24:1015 Complexation reactions 21:508,511 Complex-built alkaloids 21:57 Complicatic acid 3:7,64 Complogenin 25:101,184,185,186,204 Comploside I 25:95 Comploside II 25:95,104,203
Comploside III 25:97 Comploside IV 25:97 Comploside V 25:97 Compositae plants 21:373,374;25:921; 30:732 as anti-inflammatory effect of 30:732 as antimicrobial agents 30:732 as antitumoral agents 30:732 as antiviral agents 30:732 biological activity of 30:732 medicinal value 30:732 pharmacological activity of 30:732 Computational molecular modeling 30:195 of AS-tetrahydrocannabinol 30:195 Computational studies 27:338 Compylotropis hirtella 25:93 COMT 21:17 Comutagenic effect 5:477 of estrogens 5:477 Con A 25:227,271,272,436,455,463, 464,477 Con A agarose 25:436 Con A hepatotoxicity 25:464 Con A induced liver injury 25:464,465 Con A model 25:463 Conangium odoratum 24:275 Concanavalin A 26:268,1135;30:4 in vitro 30:4 mitogenesis induction by 30:4 Concephalenol 2:213 ent-fl-epi-Concinndiol 25:249 Conculsive affections 22:511 Allium sativum L. for 22:511 Condensation 24:198 Condensation ofp-coumaroyl-CoA 25:655 Condensed tannins 29:572 effects on HIV- 1 protease 29:572 Conduritol B epoxide (1,2-anhydromyo-inositol) 7:37 c~-glucosidases inhibition by 7:37 [3-glucosidases inhibition by
187 7:37 chiro-inositol from 7:38 invertase binding with 7:38 Conduritol epoxides 7:37 Conduritols 14:179 Condyfolan-type Strychnos alkaloids 1:33 Condylocarpine 1:40,41,45 (+)-Condylocarpine 5:126 Condylocarpine-N4-oxide 5:125 Condylocarpine-type alkaloids 5:88,89 (+)-tubotaiwine 5:88,89 condylocarpine 5:88,89 condylocarpine-N4-oxide 5:89 tubotaiwine-N4-oxide 5:89 Condylomata acuminata 26:151 Conessine 26:837 Confertdiolide 29:90 activity in TPA assay system 29:90 activity in CRG assay system 29:90 activity in EPP assay system 29:90 Confertifolin 22:612 (+)-Confertifolin 4:405-407 (+)-euryfuran from 6:28 from 1-abietic acid 4:405-415 from D-podocarpic acid 4:405407 from Drimys species 4:404 from Drimys winteri Forst 4:418 from manool 4:424,425 in (-)-warburganal synthesis 4:418 synthesis of 4:405-419 1,2-syn-2,3-anti-Configuraiton 12:35,36,41,43,48 syn-Configuration 14:753 Configuration 5:704,706;27:471 of guggultetrol 5:704,706 of secondary hydroxy 27:471 arabino-Configuration 5:704 D[(R)]-Configuration 6:387 ofN-acetyl muramic acid 6:387 Conformational analysis 24:319,342 of astin B 24:342
Conformational control 11:152-158 in macrolactonization 11:152-158 Conformational effects 12:115 Conformational property 27:337 of analogs 27:336 Conformational studies 27:258-259 of (-)-cz-isoparteine 27:259 of (+)-[3-isosparteine 27:259 Conformations 27:335 ofabscisic acid 27:335,337 Conformers 27:340 ofabscisic acid 27:340 cisodial as 27:259 of sparteine 27:259 transoidal as 27:259 Confusameline 21:68 Congarosa 23:656 Congenital cytomegalovirus 30:374 autistic features in 30:374 Congo red 23:119 absorption maximum of 23:119 Congocidine 5:549 alkaline degradation 5:549 Congorinine E- 1 29:91 activity in TNFc~ assay system 29:91 (+)-[3-Conhydrine 13:483 Conicasterol 26:1176,1177 Conicasterone 26:1176,1177 (+)-Coniceine 16:466 ct-Conidendrin 20:108 from Taxus mariei 20:108 (-)-c~-Conidendrin 20:620 Conidia 9:228,230,233,238,240,241 Coniferae 7:99 Coniferaldehyde 5:471 (E)-Coniferaldehyde 5:472,475 Coniferin 5:471 Coniferyl alcohol 5:463,464,466,467, 471,472,475,495-497;25:2,666; 26:156,177 ;27:60,760 polymerization of 27:760 (E)-Coniferyl alcohol 5:472 (Z)-Coniferyl alcohol 5:472 Coniferyl aldehyde 27:763 (+)-Coniine 13:478 Coniine 21:51,97;25:528
188
Coniothyrium minitans 21:207 Coniothyrium palmarum 21:207 Coniothyrium spp. 21:207 Conium maculatum L. 22:517;25:528 for epilepsy 22:517 1,4-Conjugate addition 10:405,406 of electrophile 10:405,406 to a,[3-unsaturated carbocyclic aldimines 10:405,406 Conjugate addition 3:8;14:510;24:12, 188-190,744,747-749,775 Conjugated dienes 8:278 synthesis of 8:278 Conjugated forms 27:354 ofabscisic acid 27:354 Conjugated ketones 2:168 octant rule for 2:168 Conjugation-deconjugation epimerization 12:14 Connium 22:422 Conocarpan 26:202 Conocephalenol 9:249,252,255;18:625, 632 Conocephalum conicum 2:273,277, 278;9:249 Conoduramine 5:123;26:829 Conodurine 5:123;26:829 Con-O-methylnogarol 4:318,357 7Conopeum seuratum 17:79 Conopharyngine 5:128 Conopharyngine (10,11-dimethoxycoronaridine) 9:174,176,177 Conopharyngine hydroxyindolenine 5:128,195 Conopharyngine oxindole 5:128 Conopharyngine pseudoindoxyl 5:128,129 a-Conotoxin 21:52 c0-Conotoxin GVIA 18:722 p-Conotoxins 21:73 Conservula cinisigna 26:698 Consolida 26:868 Consolida orientalis 27:188,191 Constipation 30:194 as opioid's side effect 30:194 Constitutional isomers 27:362 of myrcene 27:363
of ocymene 27:363 structure of 27:363 Contact dermatitis 30:168-169 phenolic lipids role in 30:168169 Contents 27:413,416 of tannins 27:413,416 Conthium guiinzii 22:515 Contotoxins 21:79 Contraction 24:910-913 effect of cholecystokinin 24:910-913 Controlled crisscross annulation 13:442 Conus 25:732 Conus radiatus 21:320 Convergent lactone synthon 13:604 synthesis of 13:604 Conversion 22:135 of cortisone to cortisol 22:135 Conversion of MFA 28:333 to (+)-paraherquamide B 28:333 Conversion of PHB 28:331,335,331, 367367 to paraherquamide A 28:331,367 Convolvulanic acid A and B 15:342 Convolvulol 15:342 Convolvulus arvensis L. 15:341 ;22:518 Convolvulus pluricaulis 22:518 Convorvolus microphyllus 13:312 Convulsions 22:510-536,471,559,580, 582,633,742 Aconitumjaponicum Thunb. for 22:510 Acorus calamus L. in 22:510 Aeolanthus suaveolens in 22:511 Aglaia odorata Lour. in 22:511 Allopylus africanus Beouv. for 22:511 Aloe vera L. for 22:511 Arisaema amurense Maxim for 22:512,513 Arisaema consanguineum for 22:512 Artocarpus helerophyllus for 22:513 Caesalpinia bonduc L. for 22:514 Caesalpinia pulcherrima L. for 22:514,471
189
Canthium bibracteatum for 22:515
Casimiroa edulis for 22:515 Cassia occidentalis for 22:580, 582
Catunaregam nilotica for 22:516 Celtis cinnamomea for 22:516 Curcuma aromatica for 22:518 Deinbollia borbonica for 22:519 Desmodium polycarpum DC. for 22:519
Desmodium triflorum DC. for 22:519
Euphorbia hirta L. for 22:520 Ferulafoetida for 22:521 Ficus capensis for 22:521 Gentiana crassicaulis for 22:521 Gentiana dahurica for 22:521 Gentiana decumbens L. for 22:521
Gentiana dehurica for 22:521 Gentiana fetisowii Regel for 22:521
Gentiana macrophylla for 22:521
Gentiana tibetica King for 22:521
Gentiana wutaiensis for 22:522 Gynandropsis pentaphylla for 22:522
Hedeoma pulegioides L. for 22:522
Hoslundia opposita for 22:523 Hoya austrulis R. for 22:523 Jatropha curcas R. for 22:524 Ledebouriella seseloides for 22:524
Leucas lavandulifolia for 22:525 Lobelia inflata L. for 22:525 Mellittia usaramensis for 22:526 Micromelum compressum for 22:526
Myrica salicifolia for 22:527 Nicotiana tobacum L. for 22:527 Paeonia emodi for 22:527,528 Paeonia officinalis L. for 22:528 Paeonia suffruticosa for 22:528 Palisota ambigua for 22:528 Panax quinquefolius L. for
22:528
Phylanthus emblicata L. for 22:529
Polygonum japonicum for 22:530,633
Pothos scandens L. for 22:530 Psychotria curviflora for 22:530 Randia esculenta for 22:530 Ruta chalespensis for 22:531 Ruta graveolens L. for 22:531 Scopaliajaponica for 22:531, 742
Securidoca longepedunculata for 22:532
Solanum carolinense L. for 22:532
Tetrameles nudiflora for 22:533 use of arnica in 22:559 use of Artocarpus heterophyllus in 22:513 use of Basilicum polystachyon in 22:514 Veratrum nigrum L. for 22:534 Xylotheca tettensis var. fissistyla for 22:535 Zanthoxylum holtzianum for 22:535 Zingiber ottensi for 22:536 Convulsions, in children 22:514-516, 524,527,529,530,532,534,535,580, 582 Caesalpinia pulcherrima L. for 22:514 Canthium bibracteatum for 22:515 Casimiroa edulis for 22:515 Cassia occidentalis for 22:580, 582 Catunaregam nilotica for 22:516 Khaya ivorensis A. for 22:524 Khaya senegalensis A. for 22:524 Newbouldia leavis for 22:527 Phyllanthus urinaria L. for 22:529 Phyllostachys nigra Lodd for 22:529 Psidium guyava L. for 22:530 Spilanthes mauritiana for 22:532
190
Uncaria rhyncophylla as 22:534 Vernonia chinensis for 22:535 Vernonia hildehrandtii for 22:535 Vitex negundo for 22:535 Ximenia americana L. for 22:535 Convulsions, in infants 22:519 Desmodium pulchellum for 22:519 Convulsive affections 22:517,527 Coleus aromaticus for 22:517 Nardostachys jatamansi DC. for 22:527 Convulsive cough 22:517 Citrus maxima for 22:517 Convulsive disorders, of children 22:534 Thuja orientalis L. for 22:534 Conyza dioscoridis 28:425 Conyza filaginoides 29:586 Conyza odentophylla (Pluchea arguta) 9:65-68 sesquiterpenes from 9:65-68 Conyza steudellii 25:25 Conyza trihecatactis 25:252 Cook 29:375 allocolchicinoids total synthesis by 29:375 Cooked garlic 23:464 chemistry of 23:464 Cooke's dianion 13:594 Coomassie 9:453 Cooperia curticei 26:490 Cooxidants 19:270 (+)-Copacamphor 4:675 Copaene 8:33-36;17:608;23:535 c~-Copaene 8:33-36 Copaifera L. 25:168 Copaifera riticulata 22:360 Copalliferol A 23:533;26:561,563 Copalliferol B 23:533;26:561,563 Cope elimination 3:468,470,471,494, 110 Cope reaction 13:109 Cope rearrangement 1:182,236,416, 566,567 ;3:47,98,139,190,191,249, 372;7:216;10:236 Cope ring enlargement 12:193
Copitisine 21:84 Copper (I) catalyzed Grignard additions 10:180 Copper (I) trifluoromethane-sulfonate benzene complex 1:271,272 Copper acetylide 4:396,398 Copper amine oxidases 26:1262,1271, 1272,1275,1283 Copper catalyzed Grignard reaction 11:81,82 Coprinus mcrorhizus var. micro~porus 5:288 Coprotoxins 18:698 Copsychus saularis 5:837 hemoglobin components of 5:837 Coptisjaponica var. dissecta 26:268 Coptisine 14:793-795 conversion to ochrobirine and corydaine 1:289-291 (+)-chelamine from 14:793-795 (+)-chelidonine from 14:793-795 sanguinarine from 14:793-795 Cora islandica 5:313 Cora pavonia 5:313 Cora silandica 5:128 Coracias benghulensis 5:837 hemoglobin components of 5:837 Coracina novachollandiae 5:837 hemoglobin components of 5:837 Corallan 23:163 Corallistes fulvodesmus 25:829; 26:1213;28:688 Corallistes sp. 26:1214 Corallistes undulatus 26:1214 Corallistine 25:829,830;28:688 X-ray crystallography of 28:688 Corallistins A-E 26:1213,1214 Corallydictyals A and B 27:855,856 Corals 18:716 Corbicula sandai 26:1123 Corchorus acutangulus 18:650; 23:487,511 23-hydroxylongispinogenin from 18:650 3[3,1613,23,28-tetrahydroxyolean-
191 12-ene from 18:650 saponins of 23:511 Corchorusins 23:487 Corchorusin A 23:512 Corchorusin B 23:512 Corchorusin C 23:512 Corchorusin C~ 23:512 Corchorusin D 23:512 Corchorusin D I 23:512 Corchorusin D2 23:512 Corchorusin D3 23:512 Corculigo 25:180 Cordia goetzei 7:408,409;23:342 Cordiceps ophioglossoides 5:279,318, 320 Cordiceps sinensis 5:279 Cordigol 7:408,409;23:342 Cordigone 7:408,409;23:342 Cordoa piaca 29:777 Cordycepin 10:357,358 from 3-deoxy-2,5-di-O-(p-nitro-
benzo yl )-f3-D-erythropentosyl bromide 10:357,358 synthesis of 10:357,358 Cordycepin (3'-deoxyadenosine) 10:593 from adenosine 10:593 Cordyceps cicadea 23:115,134 Cordyceps ophioglossoides 23:133 Coreopsis parvifolia 5:800 Corepoxylone 18:195 Corey asymmetric osmylation 26:1232 Corey epoxide 13:568 Corey method 11:154,157 Corey procedure 6:562 Corey reagent 14:268;19:452 Corey's oxazaborolidine catalysts 18:182 Corey-Fuchs protocol 30:43 Corey-Kim oxidation 12:338 Corey-Mukaiyama method 1:271 Corey-Myers synthesis 6:195 Corey-Nicolaou method 12:52,53 Corey's lactone 7:480-482 Coriandrum sativum 27:376 Coriariajaponica 23:404 Coriaria nepalensis 13:311 Coriariaceae 23:404 Coriariin A 23:402 Coriariin D 23:404
Coriariin E 23:404 Coridin display activity 22:202 Corilagin (hydrolysable tannin) 29:572 effects on HIV-1 protease 29:572 Corilous versicolor 452 (S)-Coriolic acid 13:311 Coriolic acid 26:461 Coriolin B 3:7,65 Coriolins 13:6 Coriolus sanguineus 26:1012 Corlumine 21:69 Corn earworm 24:865 bioassay of 24:865 Corn Hageman Factor Inhibitor (CHFI) 29:602 effects on cz-amylase 29:601 effects on ~x-amylase inhibitor 29:602 effects on cereal ~ amylase/ trypsin inhibitor family homologue 29:601 effects on cereal s-amylase 29:602 effects on Factor XIIa 29:602 effects on CM homologues 29:601 effects on trypsin inhibitor homologue 29:602 inhibitor proteins 29:601 RA5 as 29:601 RBI (Ragi bifunctional I) as 29:601 rice allergenic protein as 29:601 SIc~4 as 29:601 Corn syrup 2:355 Cornaceae 23:405 Cornforth's methodology 30:434 Cornitermes ovatus 15:384 Cornitermes pugnax 15:384 Cornoside 16:616 Cornus florida 7:427 Cornus officinalis 23:405 Cornusiin A 23:405 Cornusiin C 23:405,409 Coronaridin 5:127,171 ;25:533;28:234 as immunosuppressive drug 25:533
192 sesterterpenes halisulfate- 1 from 28:672 suvanine from 28:672 Coronaridine hydroxyindolenine 5:127 Coronaridine-type alkaloids 5:93-101 (-)-heyneanine 5:98 (-)-ibogamine 5:93,97 (+)-heyneanine 5:94 (+)-ibogamine 5:97 10-hydroxycoronaridine 5:98 10-hydroxyheyneanine 5:99 11-hydroxycoronaridine 5:98 11-hydroxyheyneanine 5:99 18-hydroxycoronaridine 5:98 18-hydroxyvoacangine 5:1 O0 19-epi-heyneanine 5:98 19-epi-iboxygaine R 5:97 19-epi-iboxygaline 19(R) 5:98 19-epi-voacfistine 5:100 19-oxo-voacangine 5:99 19R-hydroxyconopharyngine 5:101 19S-3,19-oxidovoacangine 5:99 19S-hydroxyconopharyngine 5:101 19S-iboxygaine 5:97 3-(2-oxopropyl-)-coronaridine 5:100 3,19 R-oxide-coronaridine 5:94,98 3-/R/S-hydroxyconopharyngine hydroxyindolenine 5:101 3-cyano-voacangine 5:100 3-ethoxy coronaridine 5:99 3-hydroxycoronaridine 5:98 3-hydroxymethylvoacangine 5:100 3-hydroxyvoacangine 5:100 3-ketopropyl- 19R-heyneanine 5:100 3-oxo-conopharyngine 5:100 3-oxo-coronaridine 5:97 3-oxo-coronaridine hydroxyindolenine 5:99 3-oxo-heyneanine 5:99 3-oxo-voacangine 5:99 3-oxo-voacristine 5:100
3R/S-hydroxyconpharyngine 5:101
3R-hydroxy- 19R-heyneanine 5:94 3-R-hydroxyconopharyngine hydroxyindolenine 5:101 3-R-hydroxyisovoacangine 5:99 3S-3 [3-hydroxyethylcoronaridine 5:99 3S-hydroxy- 19R-heyneanine 5:94 3S-hydroxyvoacangine 5:100 5-oxo-coronaridine 5:98 6-oxo-coronaridine 5:98 6R-3,6-oxidovoacangine Naoxide 5:100 catharanthine 5:97 conopharyngine 5:100 conopharyngine hydroxyindolenine 5:101 coronaridine 5:97 coronaridine hydroxyindolenine 5:98 ibogaine 5:97 ibogaine hydroxyindolenine 5:97 iboxygaine hydroxyindolenine 5:97 isovoacangine 5:99 isovoacristine 5:100 tabernanthine 5:97 voacangine 5:99 voacangine hydroxyindolenine 5:100 voacristine 5:100 voacristine hydroxyindolenine 5:100 Coronarin A 23:838 Coronarin B 23:838 Coronarin E 23:809 Coronarins (A-D) 25:265,266 Coronary artery ligation-reperfusion 25:594 Coronary heart disease 24:376-381, 30:55,72 Angelica keiskei use in 30:72 role of cholesterol oxides 24:351-398 role of natural products in 30:55 Coronatine 4:690 Coronavirus A-59 21:393 Coronilla 27:519
193
Coronopifolia 25:771 Corosolic acid 27:861,862 Corossolin 26:441,442 Corphinoids 9:592 Corphins 9:597,605 Corpora allata 22:377 Corpora cardiaca 2:90,93,94,99,106, 112;9:487,490 Corriander oil 25:140 Cortex eucommia 20:646 Cortical abnormalities 30:378 Corticium caeruleum 18:712 Corticium rolfsii 21:196 A 9(1 lLCorticoids 9:426,427 Corticomimetic activity 21:657 Corticosteroids 22:134 Corticosterone 22:135 Corticum sp. 25:707 Cortinarius odorifer 22:580 Cortinarius sp. 22:556,579 Cortisone 22:135;25:516 conversion to cortisol 22:135 Corvacrol 21:598,601 Corvularia eragrostidis 29:475 Corvus splendens 5:837 (+)-Corydalic acid methyl ester 14:796799 biosynthesis of 14:796 from corysamine 14:796-799 from tetrahydrocorysamine 14:796 synthesis of 14:796-799 via hypothetical enamine 14:796 Corydalis caucasica DC. 27:163 Corydalis decumbens 21:733 Corydalis flabellata 27:169 Corydalis rutifolia 27:170 Corydalis severtzowii RgI. 27:163 Corydalis sp. 22:518 Corydalisol 6:494 from protopine N-oxide 6:494 Corydamine 4:547 Corylus 26:894,905 Corymbellus aureus 6:135 Corymbiu villosum 25:251 Corynan-17-oic acid methyl ester 14:722-724
(+)-Z-geissoschizol from 14:722724 (+)-3-epi-Z-geissoschizol from 14:722-724 using trimethyl orthoacetate 14:725 stereoselective 14:725 using dimethyl acetamide dimethyl acetal 14:722724 Corynane-strychnane series 6:503,520 Corynanthe yohimbe K. 26:143 Corynantheyohimbe alkaloids 8:283 ajmalicine 8:283 yohimbine 8:283 (+)-Corynantheal 18:332 Corynanthean 5:112,113 Corynanthean-type alkaloids 5:71,150163 Corynantheidol 25:24 Corynantheine-type indole alkaloids 25:31 Corynantheine-type oxindole alkaloids 25:26 Corynanthe-type alkaloids 15:378 Corynanthine 21:57 Coryne cassiicola 25:149 Corynebacteirum kutschei 25:452 Corynebacteirum sp. 25:145 Corynebacteriurn bovis 12:400 Corynebacterium fescians 26:618 Corynebacterium glutammicum 13:320 Corynebacteriurn parvum 23:134 Corynebacterium poinsettiae 7:357; 20:594 Corynespora cassiicola 25:149,162,166 Corynine 22:25 Corynocarpin 27:522 Corynoline 14:770 (+)-Corynoline 14:785-787 from corysamine 14:785-787 oxidation of 14:788,789 synthesis of 14:785-787 through enamine-aldehyde cyclization 14:785-788 Corynoline-type alkaloids 4:455 Corynoxine 25:27 Corynoxine B 25:27
194
Corysamine 14:796-799 (+)-corydalic acid methyl ester from 14:796-799 (+)-corynoline from 14:785-787 (+)-isocorynoline from 14:785787 (+)- 11-epicorynoline from 14:785-787 (+)- 11-epiisocorynoline from 14:785-787 Corythuca 26:443 Corytuberine 18:58 (+)-Corytuberine 30:563,589 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:589 Cosciansterias tenuispina 7:298; 15:46,51,52 cosicinasteroside D from 7:298 Coscinasteroside A-C 15:53 Coscinasteroside D 7:298,302,53 Coscinasteroside E-F 15:53 Coscinoderma mathewsi 25:699;28:672 as protein phosphatase inhibitor 28:672 Coscinoderma sp. 28:670 Cosculine 26:824,826 (+)-Costaclavine 18:336 Costaricensis 26:484 Costasiella ocellifera 25:787 Costaticella hasta 17:90;18:726;21:260 harman from 18:726 pavettine from 18:726 3-Costoyloxydehydroleucodin 29:90 activity in NFkB assay system 29:90 Costunolide 7:230;20:471,472; 24:848 ;27:559;29:89 activity in AM assay system 29:89 activity in Colon-1 assay system 29:89 activity in iNOS assay system 29:89 activity in NFkB assay system 29:89
activity in ODC assay system 29:89 activity in RAS assay system 29:89 carcinoma 24:848 topoisomerase inhibitory activity 24:848 Costus speciosus 23:821 1H-Ill-COSY 21:692,732 IH-13C-COSY 21:692 ill-COSY 21:764 COSY 26:16,29,34,37,41 ofbisdesmoside 26:41 ofdianchinenoside E 26:34 of dianchinenoside F 26:37 ofvaccaroside D 26:29 2D-COSY spectrum 21:143 Cosynthetase 9:596 Cotinine 21:51;22:12 Cotinine N-oxide 22:12 Cotonefuran 23:341 Cotoneuster lactea 23:341 Cotton curve 6:542 Cotton effect 2:140,160,161,169,170, 172,173,255,286, 434,435,551,623; 19:259 Cotton pellet granuloma 25:46 inhibition of 25:46 Cottonogenic derivatives 2:166 Cotyledon bioassay 26:583 Coughing spasm 22:525 Leucas tavandulifolia for 22:525 Coulomb interactions 2:165 Coulomb's law 2:164,173 4-Coumarate 25:653,664 4-Coumarate 3-hydroxylase 5:468,469 1,4-Coumarate:CoA ligase 5:470 Coumaric acid 9:279;25:657;30:730 structure of 30:730 4-Coumaric acid 25:652,660 m-Coumaric acid 25:923,925 p-Coumaric acid 23:537,744,745,551, 825 ;25:655,657,920,925,936;28:262 in cereals brans 28:262 in spinach 28:262 in sugar beet fibre 28:262 cis-Coumaric acid 29:101 activity in CRG bioassay system 29:101
195 (E)-4-Coumaric acid 5:467,469,470 m-Coumaric acid glucuronide 25:923, 925 Coumarine isoepoxypteryxin 25:476 Coumarin-hemiterpene ethers 7:205 Coumarinolignan derivatives 5:9 Coumarinolignan isomer 5:5,6 Coumarinolignans 5:3,5,8,9,495,496 Coumarins 4:3,5,8,9,202,204-206,220, 224,225,367,372,375,377,389,391, 399,400,495,496,505,517-521, 574-575,971-1080;9:113-116,529; 20:283,497 ;22:75 ;23:356; 24:499-503 ;25:472;30:729 as antiviral compound 24:499-503 as trans-O-glucosylcinnamic acid 30:729 derivatives of benzo-~-pyrone 30:729 hepatoprotective mechanism of 25:472 structure of 30:729 Coumarin-sesquiterpene ethers 7:269 in Artemisia abrotanum 7:269 Coumarouna odorata 23:337 [3-O-cis-p-coumaroyl alphitolic acid 28:623 anti-microbial activity of 28:62 [3-O-trans-p-coumaroyl alphitolic acid 28:623 anti-microbial activity of 28:62 Coumaroyl CoA Chymo trypsins 25:388 [3-O-cis-p-coumaroyl maslinic acid 28:623 anti-microbial activity of 28:62 p-Coumaroyl tyramine 22:631 p-Coumaroyl-meso-tartaric acid 23:764 11-O-p-Coumaroylnepecticyn 27:477 structure of 27:477 3-O-Coumaroylquinic acid 25:920 4-O-Coumaroylquinic acid 25:920 5-O-Coumaroylquinic acid 25:920 p-Coumaroylquinic acids 28:262 in sweet cherries 28:262 p-Coumaryl alcohol 27:760 polymerization of 27:760
4-Coumaryl alcohol 5:463,467 trans-p-Coumaryl diacetate 23:801 Coumaryl glycosides 25:543 vanicoside A 25:543 vanicoside B 25:543 p-Coumaryl-CoA 25:652;27:768 p-Coumaryl-hydroxy oxyagmatine 27:765 peroxidase-catalyzed dimerization of 27:765 p-Coumaryl-hydroxyagmatine 27:765 peroxidase-catalyzed dimerization of 27:765 Coumermycin A 1 23:357 Coumestrans 27:894 Coumestrol 26:472 3~-O-cis-Coumroylmonogynol A 20:704 from Salvia montbretii 20:704 3~-O-trans-p-Coumroylmonogynol A 20:704 from Salvia montbretii 20:704 Counter-current chromatography (CCC) 25:205 IH-15N Coupling 26:1047 as structural probe 26:1047 Coupling constants 6:128,129 of 18-epi-dialdehydes 6:128,129 Coupling reactions 26:113,114,119 of secologanin 26:113,114,119 Covalent interactions 26:995-1001 of HA with 26:995-1001 Cowania mexicana 24:249 ' Cowaxanthone 26:805,806 Cowdria ruminantium 28:394 as rickettsial pathogens 28:394 COX enzymes 29:672 expression of 29:672 in hormonal production 29:672 in platelet aggregation 29:672 in prostacyclin production 29:672 in wound healing 29:672 inhibitors of 29:673 mechanism of action of 29:673 role in Alzheimer's disease (AD) 29:673 role in kidney function 29:672
196
role in pregnancy 29:672 role in stomach 29:672 COX inhibitor 29:673 ;30:192 allergic attacks-promotion by 29:674 aspirin as 30:192 aspirin-induced asthma (AIA) syndrome by 29:675 assay for 29:677 asthmatic attacks-promotion by 29:674 baicalin as 29:680 cell line based assay for 29:677 enzyme immunoassay (EIA) for 29:677 for familial adenomatous polyposis 29:674 ibuprofen as 30:192 in AD pathogenesis 29:673 in bladder tumor 29:673 in breast tumor 29:673 in cancer treatment 29:673 in cerebrovascular diseases 29:674 in osteoarthritis 29:673 in rheumatoid arthritis 29:673 in skin treatment 29:673 indomethacin as 30:192 naproxen as 29:673 radioimmunoassay for 29:677 rofeCOXib as 29:673 role in broken bone growth 29:674 role in congestive heart failure 29:674 role in exacerbate coronary disease 29:674 role in immune system 29:674 role in renal failure 29:674 role in ulcer healing 29:674 scintillation proximity assay for 29:677 to alleviate symptoms 29:673 to treat pain 29:673 to treat swelling 29:673 toxicity of 29:674 up-regulation of 29:673 wogonin as 29:680
COX/LOX dual inhibitors 29:671,675 as anti-inflammatory agents 29:671 assays for 29:676 cardio-protective functions of 29:676 fromAcacia catechu 29:678 from Scutellaria baicalensis Georgi. (Lamiaceae) 29:678 from Scutellaria lateriflora L. 29:678 natural type of 29:671 nonsteroidal anti-inflammatory drugs (NSAIDs) as 29:672 prostaglandins suppression by 29:676 role in angiotensin II-induced contractions 29:675 role in coronary vasoconstriction 29:675 role in lens protein-induced occular inflammation 29:675 therapeutical benefits of 29:675 COX/LOX natural dual inhibitors 29:681 3 -( 4 '-aceto xy-3 ', 5 '-dime th yl) benzylidene- 1,2-dihydropyrrolo [2,1-[3]quinazoline-9-one as 29:693 acetylenes as 29:682 aethiopinone as 29:688,691 alcohols as 29:681 aliphatic sulfides as 29:684 alkaloids as 29:692 alkamides as 29:683 artonon E as 29:706 atractylochromene as 29:695 aucubin as 29:686 bornyl ferulate as 29:696 ~-boswelic acid 29:692 buddledin A as 29:687 6-(3-carboxybut-2-enyl)-7hydroxy-coumarin as 29:699 catechins as 29:708 centaureidin as 29:704 chalcones as 29:707 chlorogenic acid as 29:697 cis-hexadec- 11-en-7,9-diynote acid as 29:683
197 coumarins as 29:699,700 crysins as 29:702 curcumin as 29:695 daphnetin as 29:699 6-demethyl-vignafuran as 29:709 (2,3-dihydro- 1H-pyrrolizin-5-yl) acetic acid as 29:693 5,3 '- dihydroxy-4 '-methoxy- 7carbomethoxyflavonol as 29:704 11,12-dihydroxy-6-oxo-8,11,13abietatriene as 29:688 11 (S), 16(R)-dihydroxy-octadeca9Z, 17-diene- 12,14-diyn- 1-yl acetate as 29:682 diterpenes as 29:687
dodeca-2E,4E,8Z, 10E/Ztetraenoic acid isobutylamide as 29:684 E-isolinaridial as 29:690 E-isolinaridial methylketoine as 29:690 epigalloactechin-3-gallate (EGCG) as 29:708 falcarindiol as 29:682 fatty acids as 29:681 fisetin as 29:704 flavones as 29:702 flavonoids as 29:700 flavonols as 29:704 from Aaronsohnia 29:683 from Achillea 29:683 from Allium sativum L. 29:684 fromAllium ursinum 29:684 from Anacyclus 29:683 from Angelica pubescens F. Biserrata (Apiaceae) 29:699 from Artocarpus communis 29:706 from Asteraceae 29:703 from Atractylodes lancea 29:694 fromAtuna racemosa 29:708 from Bidens campyltheca Schultz 29:682 from Boswellia serrata Roxb. (Burseraceae) 29:691 from Buddleja globosa Hope (Buddlejaceae) 29:686 from Callna vulgaris 29:691
from Ceiba pentandra 29:708 from Celastrus orbiculatus 29:708 from Chymacyparis taiwanesis 29:698 from Curcuma longa 29:695 from Echinacea angustifolia 29:684 fromEchinacea species 29:683 from Euniceafusca 29:690 from Helichrysum picardii 29:702 from Ircinia spinosula 29:694 from Linaria saxatilis var. glutinosa 29:689 from Macfadyena unguis-cati 29:696 from Morus mongolica 29:705 from Nigella satvia L. (ranunculaceae) 29:694 from Notopterygium incisum T. 29:696 from Peucedanum ostruthium (L.) 29:699 from Phillyrea latifolia L. 29:685 from Piper sarmentosum Roxb. 29:684 from Pseudopterogorgia elizabethae 29:689 from Psoralea corylifolia L. 29:705 from Punica granatum, L. Punicaceae 29:701 from Salvia aethiopis L. (Labiatae) 29:690 from Salvia athiopis (Labiatae) 29:687 from Saposhnikovia divaricata 29:682 from Scrophularia scorodonia L. 29:685 from Sideritis angustifolia 29:687 from Sideritis mugronensis 29:701 from Sophora flavescense 29:705 from Syzygium carynocarpum
198 29:708 from Syzygium malaccense 29:708 from Tanacetum microphyllum 29:703 from Tanacetum parthenium (L.) 29:686,703 from Tanacetum vulgare 29:703 from Teucrium species 29:687 from Urtica dioica L. (Urticaceae) 29:697 from Vantanea peruviana 29:708 from Zanthoxylum chalybeum Engl. 29:692 fuscoside B as 29:691 gnaphalin as 29:704 gossypetin as 29:704 gossypin as 29:704 gossypol as 29:697 harpagosides as 29:686 6-hydro xy-2-(2 hydroxy-4methoxyphenyl)benzo furan as 29:709 3-hydroxy-flavone as 29:704 hypolaetin as 29:702 hypolaetin-8-glucoside as 29:702 iridoids as 29:685 kaempferol as 29:704 kenusanone C as 29:705 kurarinone as 29:705 kuwanon C as 29:702 lagascatriol as 29:688 linoleic acid as 29:682 medicarpin as 29:709 6-methoxy luteolin as 29:702 6-methoxy luteolin-3'-methyl ether as 29:702 6-methoxy-kaempferol-3,4'dimethyl ether as 29:704 methyl 1-propenyl disulfide 5oxide as 29:685 O-methyl-pseudopterosine as 29:689 5-methyl-sophoraflavanone B as 29:705 morin as 29:704 morusin as 29:702 myricetin as 29:704
naphthol as 29:698 naringenin as 29:705 naringin as 29:705 oleic acid as 29:682 palmitic acid as 29:682 parthenolide as 29:687 pentadeca-6,8, lO-triynoic acid as 29:683 phenethyl ferulate as 29:696 phenolic compounds as 29:695 1-propenyl 1-(1-propenyl sulfinyl) propyl disulfide as 29:685 psoralidin as 29:706 quercetagetin 3,6,3'-trimethyl ether as 29:704 quercetin as 29:704 6-(2-quinolinymethoxy)etodolac as 29:693 quinones as 29:694 rutin as 29:704 safynol-2-O-isobutyrate as 29:683 sangenon D as 29:706 sanggenon B as 29:706 sesquiterpenes as 29:686 sophoraflavanone D as 29:705 sophoraflavonone G as 29:705 tanaparthin-ct-peroxide as 29:687 teucrin A as 29:688 thymoquinone as 29:695 triterpenoids as 29:691 tropolone as 29:698 ursolic acid as 29:692 COX- 1 enzyme 30:192 in kidney 30:192 in stomach 30:192 physiological effects of 30:192 role in nflammation 30:192 COX-2 enzyme 30:192 inflammation induction by 30:192 COX-2 gene expression 30:319 in RAW2647 macrophages 30:319 COX-2 inhibitors 30:192 celecoxib as 30:192 in treatment of inflammatory
199 disorders 30:192 in treatment of pain disorders 30:192 rofecoxib as 30:192 COX-3 enzyme 30:192 in brain 30:192 ~SC-oxepane 10:212,213 synthesis of 10:212,213 Coxiella burnetii 28:394 in cattle 28:394 in sheep 28:394 Coxsackievirus 30:412 Aloe barbadensis against 30:412 Coyotillo 22:558 CP-263114 24:434,435 weak inhibitor of 24:435 Cp2ZrC12. AgC104 10:370 aryl C-glycosides from 10:370 CPH82 26:170 for treatment of rheumatoid arthritis 26:170 ~SC-phytosphingosine 18:485,486 enantioselective synthesis of 18:485,486 CPI-CDPI2 3:362,367-370 CPMAS spectra 5:776 of 6-hydroxyperezone 5:776 C-prostaglandins 16:367-368 synthesis of 16:367-368 CPT activity 21:458 CPT-11 20:458 C-pyranosides 10:340 synthesis of 10:340 Cram (1,2-syn) coupling product 12:42, 43,45,48,50,55 Cram ( 1,2-syn)-selective coupling reaction 12:35,36 ofchiralvinyl halide 12:35,36 with A chiral-(x-methylsubstituted aldehyde 12:35,36 Cram addition 16:345 of enolates 16:345 of 2-1ithiofurans 16:346 Cram rule selectivity 1:608 Cram selectivity 19:473 Cram's rule 14:482;16:350 Cram's chelation model 19:320,482 Cram's product 19:471,476 Crambescidine 21:79
Crambesescidin 22:35 Cramer reaction 8:77,80 Cram's cyclic model 4:201,491 of 1,2-asymmetric induction 4:201 Cram-selective aldol-lactonization 14:115 Crassin 8:15,19-30 antitumor activity of 8:15,19 titanium-induced coupling 8:19-30 (+)-Crassin 8:29,30 Crassin acetate 8:15,20 antibiotic activity of 8:15 ~H-NMR spectrum of 8:20 mass spectrometry of 8:20 X-ray analysis of 8:20 synthesis of 10:6,7 Crassin alcohol 10:7 Crataegus monogyna 21:502;22:118; 29:579 Crataegus pinnatifida 27:861 ;29:588 Crataegus sinaica 21:507 Crataegus sp. 21:535 Crataeva nurvala 5:209 Creatine kinase (CK) 25:527;30:837, 844 hydrolysis by F-II 30:837 Crebanine 21:57 Crella sp. 25:704;28:706,707 crellastanin A from 28:706 crellastatins B-M from 28:707 Crella spinulata 25:832;28:708 benzylthiocrellidone from 28:708 dimedone unit of 28:708 Crellastatin 25:704 Crematogaster deformis 15:383 Crematogaster lineolata 6:454 Crematogaster scutellaris 6:422,453, 455 Crenomytilus grayanus 30:408 anti-influenza activity of 30:408 Crepidamine 12:277,285 Crepidine 12:285,287 from Dendrobium crepidatum 12:285 X-ray diffraction studies of 12:285
200
Crescentia cujeta 20:494 furanoaphthoquinones from 20:494 p-Cresyl methyl ether 6:83,84 Birch reduction of 6:83,84 (+)-9-pupukanone synthesis from 6:83,84 Creulide 25:690 Cribochalina sp. 25:900 Cribraria intricata 29:256 fruit bodies of 29:256 Cribraria purpurea 29:258 antimicrobial activity of 29:258 crude extract of 29:258 Cribricellina cribraria 17:79,8990;21:260;25:819;28:619 [3-carboline alkaloid from 28:619 carboline from 28:619 1 -ethyl-4-methyl-sulfone- ~antimicrobial activity of 28:619 Cribrocalina vasculum 9:37 dihydrocalysterol from 9:37 petrosterol from 9:37 Criegee rearrangement 14:128 Crimean-Congo haemorrhagic fever virus (CCHFV) 30:412 Crimmins synthesis 12:11,12 Crinine 20:325,20:351,20:369,20:384 Crinitol 20:25 from Cystoseira crinita 20:25 from marine algae 20:25-37 from Sargassum tortile 20:26,20:27 Crinoidea 7:266,100-103 Crinosterol 16:322,332,334 Crinum americanum 26:616 Crinum asiaticum 18:687 Crinum oliganthum 20:234 mesembrenol from 20:234 Criptococcus neoformans ATCC 90112 28:476 Crisophanol 30:306 structure 30:306 Crispolide 27:560 Cristacarpin 20:496,20:497 Cristaria plicata 25:868
Crithidia deanei 2:296-298 polysaccharides in 2:296-298 Crithidia fasciculata 2:295-297,577 Crithidia guilhermei 18:791,792 Crithidia harmosa 2:298 Crithidia luciliae 2:298,791,792 Critonia quadrangularis 24:103 CRO 25:46 Croalbinecine 1:230,238,484,485 Crocetin 20:726;25:958;26:293297,299,301-303,305,307 ;28:314; 30:529 structure of 28:314;30:529 Crocetin di-(fl-D-digentiobiosy)-ester (crocin) 25:956 Crocetin di-(fl-D-gentiobiosy 1)-(fl-Dglucosyl)-ester 25:956,957 Crocetin di-(fl-D-glucose)-ester 25:956,957 Crocetin diglucose ester 25:955,959 Crocetin gentiobiose glucose 25:955 Crocetin gentiobiose glucose ester 25:959,966 Crocetin glucose esters 25:957;968 Crocetin glucosylation 26:307 Crocetindialdehyde 20:568,20:572 Crocin 25:956,957,959,964,965,968; 26:294,295,299,303,305 ;28:315 artificial pathway of 28:314 Crocin effects 28:316,319 on LTP-blocking effects of ethanol 28:316 on TNF-cz-induced cell 28:319 Crocin-1 26:299,300,301 Crocin-2 26:301 Crocin-3 26:301 Crocin-4 26:301 Crocin-5 26:301 Crocus sativus L. 22:518;26:293, 294,296,302-307;28:313-315 anti-tumor activity of 28:314,315 as coloring agent 28:313 ethanol extract of 28:315 effect on central nervous system 28:315 for flavoring 28:313 for sedative in convulsions
201
22:518 uses in medicine 28:313 Crocus sp. 26:297,299 carotenoids from 26:297,299 derivatives of 26:299 Cromolyn 22:170 Croomiajaponica 21:759 Cross coupling reactions 16:417 intramolecular 10:163 Pd-catalyzed 10:161,162 with (Z)-tributylvinyl-stannanes 10:162 Cross relaxation rates 2:60,61 Cross-aldol reaction 12:297 of (7R, 8aS)-8-hydroxy-8-methyl7-oxoindolizidine 12:297 Cross-aldolisation 12:289,298 Crossandra pungens 27:191 Crossaster papposa 7:298,299;15:61,69 Crossasteroside A 15:61 from Crossaster papposus 15:61 Crossasteroside P~ and P2 15:69 Crossasterosides A-D 7:299,301 Cross-Claisen condensation 11:114 Cross-condensation 30:218,219 products of 30:219 Cross-conjugated hydronaphthalene dienones photochemical 14:356 asymmetric cycloaddition of 14:505 C2-symmetric diols 14:469-518 C2-symmetric ketene acetal 14:505 chiral acetals from 14:469-518 rearrangement of 14:356 to 3-formyl chromone 14:505 Crossed Cannizzaro reaction 4:17,135 Crossed Wittig reaction 4:570 Crossed-Aldol condensation 1:596-603; 4:328,329 asymmetric induction in 4:328, 329 diastereoselective 1:596-603 Johnson-Yamamoto mechanism 1:600 Crossopetalum gaumeri 30:660,662 cytotoxic cardenolide from 30:660,662 Crossopteryx febrifuga 7:417,425
Crossostephium chinese L. 22:518 for infantile convulsions 22:518 Cross-polarization-magic angle spinning (CP/MAS) technique 23:124 application of 23:124 Crosus saliva L. 25:955,956 Crotalaria albida 25:93 Crotalaria madurensis 23:341 ;29:771 Crotalaria sp. 19:499 Crotmadine 23:341 Crotmarine 23:341 Croton 25:242 Croton cajucara 29:100 Croton genera 9:265;27:830 Croton lacciferus 23:341 Croton lechleri 22:361 Croton macrostachys 4:612 Croton oil 12:392;20:19;22:115;25:45 Croton oil induced edema (CRO) 25:45 Croton oil induced edema inhibition 25:46 Croton oil-induced ear edema 25:556 Croton oil-induced inflammator edema 25:55 inhibitory effects on 25:55 Croton tiglium 12:233;20:19;25:242 Croton zedoaria 29:90 trans-Crotonamide 8:156 cis-Crotonamide 8:156,157 Crotonate 8:410-412,427;20:836 trans-Crotonates 8:141,147,155,157 cis-Crotonates 8:155-157 synthesis of 8:155-157 (E)-Crotonic acid 11:340,341,359 (Z)-Crotonic acid 11:340,341,359 Crotonyl boronate addition 1:527 Crotyl halide 12:172 in zinc dust 12:172 with 4-acetoxy [3-1actam 12:172 Crotylborane reagent 12:36 Crotylboration 8:477;21:432 (-)-(E)-Crotyldiisopinocamphenyl borane 18:280,281 [E]-Crotylpotassium 8:477 [Z]-Crotylpotassium 8:477 Crown ether effect 11:234 Crown gall tumors 9:386 Crushed garlic 23:461
202
Crustacea 19:627;28:382;30:533 class of 28:382 Crustacyania 30:519 structure of 30:519 [3-Crustacyanin 30:533,534 Crustacyanin 6:161 Crustecdysone 19:463,627 Crynine-type alkaloids 26:615 Cryoenzymology 7:31 Cryomixture 18:836 Cryosurgery 30:405 Cryptanol 20:661 from Salvia candidissima 20:661 Cryptaustoline 3:423 Cryptaustoline iodide 6:482 Crypthecodinium cohnii 9:47 Cryptocarya caloneura 19:481 Cryptocarya pleurosperma 1:365 Cryptochlorogenic acid 23:744;25:921 Cryptocin 28:123 against phytopathogenic fungi 28:123 Cryptococcosis 2:422,433;22:60 Cryptococcus albicans 21:758 Cryptococcus albidus 5:292, 328;8:336,352 4-thioxylobiose from 8:336,352 Cryptococcus dimennae 26:618 Cryptococcus fagisuga 25:662 Cryptococcus flavescens 5:294 Cryptococcus laurentii 5:292,294,328 Cryptococcus magnus 26:618 Cryptococcus neoformans 2:292,322, 428,446 ;5:326-328,400,408 ;21:758; 22:57;248,299;23:8,10,136,242,481; 26:228,1127 Cryptococcus sp. 5:291,292,294,328; 21:192;22:248 Cryptococcus terreus 26:618 [~-Cryptoeutreptiellanone 6:150,151 Cryptogein 25:395 Cryptoj aponol 20:670 from Salvia napifolia 20:670 Cryptolepine 1:127;5:751,752;21:56; 26:1060 Cryptolepis sanguinolenta 5:751; 26:828,1060 cryptolepine from 26:828 Cryptolestes ferrugineus 8:227;19:154
Cryptoleuridine 1:365
Cryptomeriajaponica 2:402;19:246;
25:257,275;29:101 Cryptonoline iodide 6:482 Cryptophyceae 6:134-155 Cryptophycin 25:789 Cryptopine 21:68 Cryptopleurine 21:97 Cryptoporic acids 29:87 activity in AOS assay system 29:87 activity in TLO assay system 29:87 activity in PLA assay system 29:87 Cryptoporus volvatus 29:87 Cryptosporidiosis 26:788 treatment of 26:788 Cryptothetia crypta 21:252;25:712 spongouridine from 21:252 spongothymidine from 21:252 Cryptotrienolic acid 25:259 ct-Cryptoxanthin 20:727 Crysoeriol 20:712 from Salvia candidissima 20:712 Crystal structure 26:150,155;27:335 for abscisic acid 27:335 of 2'-bromopodophyllotoxin 26:150 Crystal-7 22:154 Crystallization- induced 13:76 asymmetric transformation 13:76 Crystallographic studies 27:821 Crystamidine 3:476 Crytotanshinone 22:175 Crytowolline 3:423 C-S bond 6:307,308 heterolytic dissociation of 6:307,308 homolytic dissociation of 6:307,308 CSF (colony stimulating factor) 25:455, 960,963 C-Sucrose 11:469,470 synthesis of 11:469,470 C-Trichodiene 13:520 14 CTX-3C 21:301 Cu (I)-catalysed 3:8
203
Cu (I)-Semiquinone 26:1273 Cualzorra 22:559 Cuanzin 8:283,284,289,293 antiarrhytmic activity of 8:283 antihypertensive activity of 8:283 Cuauhtemone 9:66 Cubebane skeleton 25:51,848 (+)-Cubebol 21:282 Cubitene 8:230 by c~-thiocarbanion-epoxide 8:230 from Cubitermes umbratus 8:230 synthesis of 8:230 Cubitermes 8:230;21:277 defence secretion of 8:220 Cubitermes umbratus 8:230 cubitene from 8:230 Cubugene 8:221 Cuculus micropterus 5:837 hemoglobin components of 5:837 Cuculus varius vahl 5:837 hemoglobin components of 5:837 Cucumaria echinata 15:94;28:596,720 neuritogenic activity of 28:720 Cucumaria fraudatrix 15:87,92 cucumariosides G1, C1 and C2 from 15:87,92 Cucumaria frondosa 7:277;28:720 2,6-dimethylnonane- 1-sodium sulfate from 28:720 frondogenin from 7:277 2,4,6- trimeth yl-no nane- 1-sodium sulfate from 28:720 Cucumariajaponica 7:275;15:87; 28:595 cucumarioside-A0-3 from 28:595 cucumarioside-A~-2 from 28:595 cucumarioside-A2-1 from 28:595 cucumarioside-A2-2 from 7:275; 15:87;28:595 cucumarioside-A3 from 28:595 cucumarioside-A4-2 from 28:595 cucumarioside-A6-2 from 28:595 cucumarioside-A7-1 from 28:595 cucumarioside-A7-2 from 28:595
Cucumaria koraiensis 28:599 Cucumaria lefevrei 15:92;28:596 from lefevreioside A~ from 28:596 from lefevreioside A2 from 28:596 from lefevreioside B from 28:596 from lefevreioside C from 28:596 Cucumariidae 7:275,277,280 Cucumarioside A2-2 7:275,276,15:87 Cucumarioside C1 & C2 7:275,276 Cucumarioside G~ 7:275,277,281 Cucumarioside G2 15:89 from Eupentacta fraudatrix 15:89 Cucumariosides G1, Ci and C2 15:87,92 from Cucumaria fraudatrix 15:87,92 Cucumis CMCTI-I 29:614 Cucumis CMeTI-A 29:614 Cucumis colocynthis L. 22:518 for epilepsy 22:518,519 Cucumis melo 25:390;29:614 Cucumis sativus 29:614 Cucumis sp. L. 22:518 for epilepsy 22:518 Cucumisin 25:390 Cucurbic acid 6:557 Cucurbita maxima 29:614 Cucurbita pepo 29:615 Cucurbita sp. 29:590 Cucurbitaceae 5:743,744,750; 21:634,730 saponins from 21:645 Cucurbitacin 20:4,13 Cucurbitacin B 5:750;22:97;26:868 glycoside of 5:750 Cucurbitacin D 5:750 Cucurbitacin E 5:750;22:97 glycoside of 5:750 Cucurbitacin F 25:59 Cucurbitacin I 5:744,751 Cucurbitacin J 5:744,751 Cucurbitacin L 5:750 glycoside of 5:750
204
Cucurbitane 25:50,57,59 23,24-dihydrocururbitacin F 25:50,57,59 Cucurbitane 5:744,750;22:95 Cucurbitane triterpenoids 24:249 Cudrania cochinchinenesis 28:203 Cudrania tricuspidata 28:203 Cudraphenone B 28:230 biological activity of 28:230 Cudraphenone D 28:230 biological activity of 28:230 CuI-tributylphosphine complex 4:556, 557 tandem Michael addition with 4:556,557 Culcia novaeguinea 7:298;15:69 Culcitoside C~ 15:69 Culcitoside C4-C8 15:71 Culcitosides C~-C3 7:96,109,110 cumambrin A,B 7:235 cyclases 7:96,109,110 diterpene synthetase 7:109,110 from Culcita novaeguinea 7:298 sesquiterpene synthetase 7:109,110 Culex pipiens fatigans 3:157 Culex pipiens pallens 21:252 Cullmorum 6:219,220;9:206, 207,215,216 Culmorone 6:219,220,536 Culture medium 17:432 effect on prod. of polyphenols 17:432 Cumambrin A 27:576;29:90 activity in NFkB assay system 29:90 Cumambrin A,B 7:235 Cumambrin B 27:576 C27-p-umaroxy-ursolic acid 20:6 Cuminaldehyde 29:83 activity in AM bioassay system 29:83 Cuminum 29:579 Cuminum cyminum 28:427 acaricidal activity of 28:427 Cuminyl alcohol 29:83 activity in AM assay system 29:83 Cumulated ylides 4:658
Cunningham 19:627 Cunninghamella 25:172 Cunninghamella blakesleana 23:22,42;25:172,173 Cunninghamella echinulata 20:792 Cunninghamella elegans 20:214 Cunninghamia lanceolata 25:251; 29:101 Cupalaurenol 5:368,7 Cupalaurenol acetate 5:368,7 Cuparene 8:12 Cuparene-related sesquiterpenes 17:7 (-)-c~-Cuparenone 10:407 (+)-a-Cuparenone 10:407 Cupolamide A 26:1190 Cuprate 1:456,457,459,460 Cupressaceae 21:615;25:246,249 Cupressus sempervirens 25:253 Curacin A 25:732,733,876 Curacin B 25:876 Curacin C 25:876 Curacin D 25:876 Curacins 25:876 Curan-type Strychnos alkaloids 1:33 Curare alkaloids 20:269 (-)-Curcuhydroquinone 23:164 (-)-Curcuhydroquinone- 1-monoacetate 23:164 Curculigo latifolia Dryand. 15:36; 27:18,39 curculin from 27:18,39 Curculigo orchioides 21:651 ;24:145, 146;25:227 Curculigosaponin G 24:145,146;25:227 Curculin 15:36 from Curculigo latifolia 15:36 Curcuma 23:825 Curcuma aromatica 22:518; 24:269;27:852 ;29:577 for convulsions 22:518 Curcuma comosa 26:884 anti-inflammatory activity of 26:884 Curcuma longa 8:52;13:660;17:363, 373,377,379;20:734 ;21:616;24:272, 274 ;25:469,476;26:457,474,882,887; 27:852;29:695 curcumin from 26:887 hepatoprotective activity of
205
25:469 serum transaminase activity of 25:469 Curcuma phaeocaulis 24:274 Curcuma sp. 17:358;26:905 Curcuma tinctoria 17:357 Curcuma xanthorrhiza 17:364;23:836; 24:274,288;26:883,884;27:852;29:87 Curcuma zedoaria 24:272;25:172;29:87 Curcumanolide B 23:827 Curcumene 5:777-778;23:181 ~-Curcumene 5:803-805,20:6;23:830 (+)-y-Curcumene 8:39 Curcumenol 29:90 activity in HPT assay system 29:90 Curcumia longa L. 25:469 hepatoprotective activity of 25:469 serum transaminase activity of 25:469 Curcumin 13:660,357,363,374,379; 17:374;20:729,734,772;21:616; 23:316,832;24:215-264 ;26:305 anti-tumor promoter 24:215-264 Curcumin 1-III 26:474 Curcumin (turmeric yellow) 25:44,469, 470,541 Curcuminoids 24:216 Curcuphenol 5:804;23:164 (-)-Curcuphenol acetate 23:164 (-)-Curcuquinone 23:164 (+)-Curcuquinone 8:39 Curdione 23:825 Curtius degradation 19:145 Curtius reaction 12:448,458 Curtius rearrangement 1:6,51,309,637, 638;19:68,79;21:435,746;26:1237 Curtius-type reaction 13:95 Curtobacterium pusillum 23:92 Curucumanolide A 23:836 Curucumanolide B 23:836 Curvularia lunata 9:412,417,418; 25:254,260,261,263;26:227 Curylus heterophylla 23:403 Curzenone 827 Cuscohygrine 22:724 Cuscuta europea L. 22:518 for fits 22:518
Cuscuta reflexa 25:944,945;29:573 Cushman study 27:925 Cussonia barteri 7:427;21:673 oleanolic acid glycoside from 21:673 Cussonia spicata 7:427,435 Cusumis sativa 24:57,60 Cutaneous leishmaniasis 30:742 treatments for 30:742 use of medicinal plants 30:742 Cutleria multifida 21:306 CVE 30:768,769,770,773,775,776 against Listeria 30:768 against listerial infection 30:768 as therapeutic agent 30:773 as prophylactic 30:773 effect on expression of mRNA 30:770 effect on growth of Listeria monocytogenes 30.769 in antigen-specific response 30:773 in mice 30:773 on IFNy mRNA expression 30:775 on IL- 12 mRNA expression 30:775 therapeutic potential of 30:768 to control allergy 30:776 CVE-treated MAIDS 30:769,770 Listeria antigen in 30:770 DTH response in 30:770 CVS 25:443,445,447,450 antimetastatic effect on 25:441 CVS induced antitumor immunity 25:454 antitumor effect 25:440 resortive effect on progenitor cells 25:448,449 and tumor specificity 25:442 Cyamopsis tetragonolobus 26:1139 (+)-Cyanidanol-3 22:429 Cyanide versus isocyanide formation 3:207 Cyanidin 3-galactoside 23:745,750 Cyanidin 3-glucoside 23:749,752 Cyanidin 3-O-galactosides 22:634 Cyanidin 3-rutinoside 23:746 Cyanidin 3-sophoroside 23:750
206
Cyanidin 3-sophoroside-5-glucoside 23:757 Cyanin chloride 20:738 4-S-Cyano derivative 8:335,336 Cyano trapping 1:105 Cyano [3-C-glycosides 10:372 1,2-O-Cyano (p-metho xy)benzylidene- c~D-galactose 14:252 2-Cyano- 1,1-dimthylethyl 4:285 2-Cyano-4-O- [3-D-glucopyranosyltrans-buten-2-ol 21:738 2-Cyano-6-oxazolo-piperidine 12:351 2-Cyano-azadiene Diels-Alder reaction 16:458 Cyanobacteria 21:303,367;23:234,344 Cyanobacterial hepatotoxins 9:496-499 Cyanobacterial inhibitory compounds 26:357-364 Cyanobacterial origin 20:887-913 Cyanobacterial toxicity 26:376 Cyanobactericides 26:382 c~-Cyanobenzyl alkyl ether 14:473 synthesis of 14:473 Cyanoborohydride 8:205 Cyanocobalamin 9:598,603,606 Cyanocycline A 10:103 antitumor activity of 10:103 Cyanocycline F 10:104 Cyanoepithio alkanes 26:1074 2-Cyanoethyl group 4:285 bis-(2-Cyanoethyl) phosphorochloridate 8:74 Cyanogen bromide 2:34 fragmentation of glucoamylase 2:34 Cyanogen iodide (ICN) 28:336 for cyanation 28:336 for cyanation of aromatic compounds 28:336 of alkenes 28:336 Cyanogenetic glycoside 15:226 Cyanogenic glucosides 21:737;22:75 7-Cyanogenic glycoside 21:738 Cyanoglycosides 30:453 Cyanohydrin 8:198;21:740 cyclization of 8:198 synthesis of 8:225,226
Cyanohydrin ether 8:177 alkylation of 8:177 cyclization of 8:178 Cyanomorpholino sugar 14:21 Cyanonaphthyridinomycin 1O:103,104 Cyanophyceae 6:134 Cyanophyta 10:250 c~-Cyanopiperidine 19:35-36 [3-Cyanopropanal dimethylacetate 21:406 Cyanopropylsiloxane 9:456 15-Cyanopuupehenone 21:363 3-Cyanosampangine 23:6 4-Cyanosampangine 23:6 Cyanosiloxane 9:454,456 (-)-l-Cyanovinyl (1' S)-camphanate 14:179 1-Cyanovinyl (1R)-camphanate 12:340 (+)- 1-Cyanovinyl ( l'R)-camphanate 14:179 from (1' R)-camphanic acid 14:179 1-Cyanovinyl (1S,5R,7S)-3-ethyl-2-oxo6,8-dioxa-3-3-azabicyclo [3.2.1 ] octan-7-exo-carboxylate 2:340 3-Cyanovoacangine 5:124 3-C-(c~-Cyano-c~-ethoxycarbonyl) methylene derivative 10:412 Cyantions 1:612,613 diastereoselective 1:612,613 of acetals 1:612,613 Cyasterone 25:59 Cyathocaline 20:485 Cyathus sp. 24:942 cyathanes from 24:942 Cybister tripunctatus 5:700 Cycadaceae 21:97 Cycas cricinalis 25:529 Cycas revoluta 29:578 Cycasine 21:97 Cyclachaenin 5:728,729 Cyclaradine 8:148 Cyclase 7:109,110 synthesis of 8:298 from sweet marjoram (Marjoram hortensis) 11:222 diterpene synthetase 7:109,110
207
sesquiterpene synthetase 7:109,110 Cyclase activity 30:639 ofMaytenus aquifolium 30:639 ofSalacia campestris 30:639 Cyclazocine 30:198,199 3-carboxamido analogue of 30:198 structure of 30:199 Cyclea atjehens& 20:552 Cyclea barbata 20:522 Cycleahomine (bisbenzylisoquinoline) 29:578 effects on ACE 29:578 Cycleanine 25:472,476;26:824 Cycleatjehenine 26:824 Cycleatjehine 26:824 Cyclic adenosine monophosphate 25:260,509,598 Cyclic adenosine monophosphate (cAMP) phosphodiesterase 24:855 Forsythia suspensa inhibition of 24:855 Cyclic adenosine-5'-diphosphateribose 25:547 Cyclic adenosine-5'-diphosphateribose (CADPR) nicotinic acid adenine dinucteotide phosphate(NAADP) 25:516 Cyclic ADPR 25:517 Cyclic amino acids 13:507-512 synthesis of 13:507-512 Cyclic AMP 7:387 Cyclic AMP phosphodiesterase 5:512, 513,520;25:539 3',5'-Cyclic AMP-dependent protein kinase (PKA) 25:512 Cyclic AMP-dependent protein phosphorylation 25:483 3'-5'-Cyclic AMP-sensitive cation channels 25:483 Cyclic dependent kinase 25:4,798,799 Cyclic depsipeptides 21:296 Cyclic dienes 8:141 Cyclic diterpenoids 30:707 classification of 30:707 Cyclic ene-dione acceptors 4:709,711 in Michael reaction 4:707-709
Cyclic enones 14:502 [2+2] photocycloaddition of 14:502 with chiral ~,[3-unsaturated acetals 14:502 Cyclic GMP-phosphodiesterases 25:54I Cyclic halo ether compounds 19:411461 from marine origin 19:411-461 synthesis of 19:411-461 Cyclic hexadepsipeptides 13:533 Cyclic hexapeptide 22:297 Cyclic hydroxamic acid 27:199 c~-hydroxylation of 27:199 Cyclic ketones 6:313-315,332,333 synthesis of 6:313-315,332,333 Cyclic nucleotide phosphodiesterase 25:512 Cyclic oligopeptides 24:304,307 Cyclic oligosaccharides 27:365 Cyclic peptide 23:341 Cyclic peroxides 5:353-355;23:341 Cyclic polypeptide inhibitors 27:879 Cyclic steroidal glycosides 15:59,60 Cyclic sulfides 8:205 Cyclic systems 6:33-38 synthesis by modifications of 6:33-38 de novo synthesis of 6:33 Cyclic voltammetry 30:543 Cyclic ~-keto esters 1:697-701 reduction with yeast 1:697-701 Cyclic-Cram diastereoselectivity 12:297 Cyclindramide 21:411 Cyclindrocarine 19:112 Cyclindrocarpidine 5:128 Cyclitol derivatives 7:156,157 Cyclitols 13:6 Cyclization 11:221,222;30:213,462,717 (+)-(4R)-~-terpinyl from 11:221,222 acyliminium-mediated 10:125 amide iminium ion 10:87 asymmetric 10:631-633 azido-olefin 13:447,448 bicyclic keto ester from 14:509 by C-C bond formation 10:218-231
208
by C-O bond formation 10:202 by diphenyl phosphoryl azide 10:641,644,652,656,657 by sodium bistrimethylsilylamide 6:540 catalytic 8:278 Dieckmann 13:445 enzymatically controlled 11:287 in silver (I) triflate 12:81 intramolecular 10:631-633; 11:253,254 ;12:156 iodotrimethylsilane mediated 11:109 Lewis acid mediated 10:87 ligase catalyzed 14:304,305 mechanism of 6:314,315;7:335338,358-360 of (-)-(3 R)-linalyldiphosphate 11:221,222 of (L)-glutamic acid 6:438-440 of acyclic nucleoside derivative 10:588,592 of allyl glycidyl ether 10:588, 589 of c~-mono-alkoxylated piperazinediones 12:90 of cyanohydrin ethers 8:194 of epoxy alcohol 10:599,600 of epoxy allylic ether 10:590, 591 of glucose 11:219 ofhexapeptide 10:289,290 of ketoesters 4:328-330 of lycopene 7:334-354 of neurosporene 7:334-354 of nitroketone 6:447,448 of oligoribonucleotides 14:304,305 of 3S isomer of 2,3-epoxy-2,3dihydrosqualene 30:717 of squalene 30:717 of triterpenoids 30:717 of vinyl sulfoxides 10:673-676 of vinyl sulfoximines 10:679 of ot-diazo ~-keto ester acetals 14:509 oxetane ring formation by 10:588,589 oxetanocin A synthesis by
10:588-592 palladium catalysed 1:258 reductive 8:278 regioselectivity of 6:540 Rh (II)-catalyzed 14:509 stereochemistry of 7:338-354 stereoselectivity of 6:540 transannular 13:440 using TFA-water mixture 30:462 via SN2 displacement 11:253, 254 with copper (II) perchlorate 12:85 with diphenyl phosphoryl azide 10:289,290 with Nicolaou reagent 10:121, 122 with pyridinium chlorochromate 11:93,94 Cyclization reaction 6:15,43,44 [2+2] cycloadditions 6:15,43,44 diastereoselective 14:506,507 in (+)-A 9(12)capnellene synthesis 6:43,44 in cadinane synthesis 6:15 in elemane synthesis 6:15 in germacrane synthesis 6:15 of 6-octen-l-al 14:506,507 Rh(I) catalyzed 14:506,507 Cyclized branched oligoribonucleotides 14:486,489 (-)-Cyclizidine 12:305,306 biological activity 12:305,306 Cyclo-( 1-3 )- [3-galactooligosaccharide s 14:237 Cyclo-(1-6)-[3-galactooligosaccharides 14:237 Cyclo-(L-Pro-L-thiopro) 25:829 Cyclo-(L-Pro-Met) 25:829 9[3,19-Cyclo- 11-oxo steroidal alkaloids 2:205,206 9[3,19-Cyclo-20-oxo-(16-17) steroidal alkaloids 2:2079,19-Cyclo-5 ot,9[3-1anostane 27:447 Cycloacanthaside F 25:197 Cycloaddition 16:7,47 1,3-dipolar 1:247-250 asymmetric 1:371-375;11:300
209 by 3-hydroxy- 1-arylthiobutene 4:477 by chlorosulfonyl isocyanate 4:475 E-exo-transition state 1:370,371 enolate induced 1:502-503 intramolecular [3+2] 1:247-250 intramolecular [4+ 1] 1:247-250 intramolecular nitrile oxide [INOC] 1:477,480,481 ionic 5:793 lanthanide catalyzed 1:413,415 MgBr2 mediated 1:474 Ni (O)-catalysed intramolecular 3:78,79 of (N-acryloyl) bornan- 10,2sultam 11:307,308 of alkene 11:468 of levoglucosenone 14:270,271 2+2]-Cycloaddition 1:263,343;4:475; 8:45,185,207;11:15-20,45-47; 12:116,150-152,160,161,173,193, 416;15:266;16:127,470,732,733 carbocyclic oxetanocins synthesis by 10:610-616 enantioselective 10:610-616 in homoerythrinan synthesis 3:481,478 of allene 16:127 photochemical 16:125,469 with dichloroketene 13:6,36 synthesis of quinoline skeleton 3:385-397 4+2]-Cycloaddition 1:282,323,420, 465;8:45,185,207;11:11,13,14,16, 260-267 ;16:4,444,493,732;19:108109,148,221,227 acid catalyzed 4:4 cycloaldolization 4:4,11,17,18, 22,23 diasteroselective 12:424,425 high pressure Eu (fod)3-mediated 4:121,143 in (+)-A -9(12) capnellene synthesis 6:43,44 in lincosamine synthesis 4:154 in purpurosamine C synthesis 4:115 of 2-alkenyltropolones 5:799
of 3-[(1S)-2-exo-alkoxy- 1 apocamphanecarbonyl]-2oxazolones 12:424,425 of c~-amino aldehydes 4:111 ofkojic acid 5:799 reverse stereoselectivity of 4:122 to dialkyl azodicarboxylates 12:424,425 transannular 5:796,797 [3+4]-Cycloaddition 1:378,522,523 1,3-Cycloaddition 1:448,449 [8+2]-Cycloaddition 1:568 [6+3]-Cycloaddition 1:569 [6+4]-Cycloaddition 1:571 intramolecular 1:571 of cyclopentadiene with tropone 1:570 of dienes to tropone 1:569-571 of 2-alkenyltropolones 5:799, 800 [4+4]-Cycloaddition 11:17 [6n+47t]-Cycloaddition 12:238 [2+2]-Cycloaddition 24:190,191 of dichloroketone 24:190,191 [2+3]-Cycloaddition 3:469 4-oxo-erythrinans by 3:469 [5+2]-Cycloaddition 8:160-163,16:552, 553;12:260,261 [3+2]-Cycloaddition 8:402; 19:66,78, 80,174,367 of 2-azaallyl fragments 1:324 of azomethine 8:402 of azomethine ylide 19:80 intramolecular 19:367 stereospecific 19:367 Cycloaddition processes 12:250-261 for tigliane ring system 12:250-261 [3+2]-Cycloaddition reaction 12:155 of nitrone 12:155 to benzyl crotonate 12:155 Cycloaddition reaction 14:502-505,747, 19:226 diastereoselective 14:502-505 with 1-trimethyl silyloxybutadiene 14:747 of quinone monoketals 5:796, 797
210
[2+2]-Cycloaddition-fragmentation 12:194,195 [4n+2n]-Cycloadditions 1:566-571 intramolecular tropone-olefin 1:568 inverse electron demand 1:566 with tropone as diene 1:566-571 Cycloadduct 12:425 chiral synthon of 2-amino alcohol from 12:425 trans-4-me tho x y-2-o xazo lidinone
from 12:425 [5+2]-Cycloadducts 16:555-559 [4+2]-Cycloadducts 16:732 Cycloalliin 23:458,461 Cycloalpegenin 25:179,184, 187,190,201 Cycloalpigenin A 25:184,201 Cycloalpigenin B 25:201 Cycloalpigenin C 25:201 Cycloalpioside A 25:201 Cycloalpioside C 25:201 9,19-Cycloanost-24-ene-3fl-ol 25:190 Cycloanthogenin 25:187 Cycloaraloside A 194 Cycloaraloside B 25:195 Cycloaraloside C 25:195 Cycloaraloside D 25:195 Cycloaraloside E 25:194 Cycloaraloside F 25:195 Cycloarbicoside A 25:202 Cycloart-24-en-3-one 9:288,289 Cycloart-24-en-3 [3-ol 9:288,289 24R-Cycloartan-3fl, 6a, 16/3-24,25pentaol, 6-dehydroxyc yc loastragenol 25:184 Cycloartane 9:267;25:61,52 Cycloartane derivatives 27:448 Cycloartane glycoside 25:221 Cycloartane saponins 25:183 Cycloartane structure 27:4 of genins 27:4 Cycloartane-type triterpene glycoside 27:473 Cycloartene triterpenes 10:151 Cycloartenol 17:622;27:447;29:586 effects on CHY 29:586 Cycloartenol ferulate 25:61
Cycloartenyl linoleate 9:461 Cycloartenyl palmitate 9:461 Cycloartobiloxanthone 28:201,230 biological activity of 28:230 from moraceous plants 28:201 Cycloasgenin C 25:185 Cycloastragenol 25:179,184,185, 186,187,190,191,192,215,217,225 Cycloastragenol-6-O-glucoside 25:224 8,14-Cycloberbines 1:188,189,192-197 Cyclobullatine-A 2:207 [2+2]Cyclobutane formation 10:611, 613 Cyclobutanes 16:553,554 protic acid rearrangement of 16:553 rearrangements of 16:554 Cyclobutanol 14:647 Cyclobutanone 10:618 oxaspiropentane rearrangement by 10:618 Cyclobutanone-ring expansion 3:23,24 (-)-E-Cyclobuxaphylamine 2:197,198 (-)-Z-Cyclobuxaphylamine 2:198,199 Cyclobuxomicreine 2:207 Cyclobuxophylline 2:207 Cyclobuxophylline-O 2:207 Cyclobuxosuffrine 2:207 (+)-Cyclobuxotriene 2:194,195 (-)-Cyclobuxoviricine 2:193,194,204 Cyclobuxoviricine 2:207 Cyclobuxoviridine 2:207 (+)-3,5-Cyclocamphanone 4:646 Cyclocanthaside D 25:197 Cyclocanthogenin 25:184,185,197 Cyclocanthoside A 25:197 Cyclocanthoside E and G 25:227 Cyclocanthoside G 25:197 Cyclocarbamations 12:411,414 Cyclocarbonate group 6:285,286 Cyclocarposide 25:193 Cyclocarposide B 25:193 Cyclocarya paliurus 27:15,28 cyclocarioside A from 27:15 cyclocarioside I from 27:15 Cyclocephaloside 25:200 Cyclocephaloside II 25:193
211 (24S,25S)-24,26-Cyclocholesterol 9:37 from Spheciospongia vagabunda 9:37 Cyclocholesterol 9:41 Cyclocinamide 25:757 Cyclocinamides A 25:761,762 c~-Cyclocitral 28:406 acaricidal properties of 28:406 (R)-(-)-Cyclocitral 6:31 pallescensin-1 from 6:31 [3-Cyclocitrol 14:673-676;20:570; 26:354;28:406 acaricidal properties of 28:406 condensation of 14:673-676 taxodione from 14:673-676 with 3-isopropyl-4-methoxybenzyl chloride 14:673-676 (-)-Cyclocolorenone 14:360 (+)-Cyclocolorenone 21:281 Cyclocolorenone sesquiterpenes 21:281 Cyclocondensation 4:130,145 and threo-selectivity 4:130,145 Lewis acid catalyzed 11:446-451 Mg Brz-catalyzed 1:415,417; 11:451 with Ce(OAc)3-BF3.OEt2 1:420,421 with Danishefsky's diene 4:122,130 with Eu FOD 1:420,421 with L-serinal 4:122 with N, O-protected c~-amino aldehyde 4:130 with silyloxydienes 4:113 Cis-f3-Cyclocostunolide 2:280,281 Cyclocurcumin 17:363;26:902 (E,E)-2,6-Cyclodecadiene 8:177 (E,Z)-2,6-Cyclodecadiene 8:177 Cyclodecadienone 8:247 by [3+3]-Oxy-Cope rearrangement 8:247 by Diels-Alder reaction 8:249 photocycloaddition 8:250 Cyclodepsipeptides 5:419,10:251, 252,263 Cyclodercitin 25:893,894 Cyclodesipeptides 25:768,884
[3-Cyclodextrin 27:368,369 for the separation of enantiomers 27:369 Cyclodextrin-hiba oil 21:620 Cyclodextrins 7:34;27:365,368 chromotographic techniques for 27:368 c~-Cyclodextrins 27:365 y-Cyclodextrins 27:365 structure of 27:366 Cyclodextrin-type compound 27:365 from (+)-a-D-glucose 27:365 Cyclodimerization 4:92,93 with DEPC 4:92,93 of tetrahydroisoquinoline precursors 6:495 7,20-Cyclo-ent-kaurane skeleton 15:167 7,20-Cyclo-ent-kaurenoids 15:112 Cycloeucalenol 9:39 obtusifuluol from 9:39 Cycloeudesmol 6:40 from Chondria oppositiclate 6:40 isocycloeudesmol relation to 6:41 (+)-ct-selinene conversion to 6:40 synthesis of 6:41 Cyclofriedo-oleanone 7:152 X-ray analysis of 7:152 from Euphorbia nerifolia 7:152154 Cyclo functionalization 6:427,428 of ethylurethanes 6:427,428 with phenylselenyl chloride 6:427,428 Cyclogalegenin 25:179,184,187, 191,196,218,225,227 Cyclogalegenoside A 25:196 Cyclogaleginoside B 25:196 Cyclogaleginosides 25:191 Cyclogibberellane 6:207 9,15-Cyclogibberellin 6:206 Cycloglycofoline 13:348,349,370-372 cis-Cyclogonionenin 18:222 trans-Cyclogonionenin 18:222 Cyclohemiacetals 27:196 synthesis of 27:197
212
Cycloheptanone 8:35 Cycloheptatriene 30:473 as achiral non-carbohydrate 30:473 Cycloheptene-6,7-dicarboxylate 9:226 Cycloheptenone enolate 6:29,30 in perforenone synthesis 6:29,30 Robinson annulation of 6:29,30 Cyclohex-2-enone 27:335 ofabscisic acid 27:335 Cyclohexadiene 12:11,12 1,4-Cyclohexadiene 27:342,343 of boat-boat inversion potential 27:343 Cyclohexadienones 5:343-346 Cyclohexane ring system 6:5,6,29,30 annulaton of 6:5,6,29,30 Cyclohexane- 1,2,-diamine 25:345 cis-l,2-Cyclohexanediol 10:324,325 trans- 1,2-Cyclohexanediol 10:324,325 1,2-Cyclohexanediones 12:376,377 bis-Fischer indolization of 12:376,377 Cyclohexanhexaol (inositol) 7:37 Cyclohexanol 11:343 Cyclohexanone 8;36;30:141 aromatization of 14:637,638 by chiral lithium amides 14:571, 572 kinetic deprotonation of 14:571,572 monoacylation of 30:141 prochiral 4-substituted 14:571, 572 Cyclohexanone aldehyde 6:61 bromochamigerene from 6:61 spiroannulation of 6:61 spiro[5.5] undecenone derivatives from 6:61 Cyclohexanone bis-epoxide 1-oxaspiro [4,5] decane ring system 21:389 Cyclohexanone derivatives 27:338 2-Cyclohexen- 1-one 11:337,338 aldols from 11:337,338 kinetic deprotonation 11:337,338 with 4-pentenal 11:337,338 1-Cyclohexene carboxyl CoA 11:190,191
Cyclohexene derivatives 4:581 synthesis of 4:581 Cyclohexene imides 12:378 arcyriaflavin A from 12:378 bis-2-chlorophenylhydrazones from 12:379 N-methylarcyriaflavin A from 12:378 1-Cyclohexenecarboxylic acid 1l: 191 trans-Cyclohexenecarboxylic acid 11:340,341 by Diels-Alder addition 11:340,341 from (E)-crotonic acid 11:340,341 from butadiene 11:340,341 deprotonation of 14:658 with lithium diisopropyl amide 14:658 Cyclohexenone ring 27:344 ofabscisic acid 27:344 Cycloheximide 25:58 Cycloheximide-induced amnesia 25:958 Cyclohexylamine 15:4 Cyclohexylidene 24:883-887 potentiating effects on neuromuscular blocking action 24:883-887 (3S,4S)-Cyclohexylstatine 12:432,433 from (4S,5S)-5-allyl-4-methoxy2-oxazolidinone 12:432,433 Cyclohexylstatine (3S,4S)-4-amino-5cyclohexyl-3-hydroxypentanoic acid) 12:432 renin inhibitor of 12:432 Cyclohexylundecanoic acid 11:190 wCycloisomerization 8:297 of cis, cis-3-carboxymuconic acid 8:297 913,19-Cyclolanost-24-ene-3fl-ol 25:181 Cyclolaurene 17:7 Cyclolaurenol 17:7 Cyclolinteinone 29:111 activity in COX bioassay system 29:111 activity in iNOS bioassay system 29:111 activity in NFkB bioassay system 29:111
213
Cyclolithistide A 26:1190 Cyclolodecene 6:541 Cyclomalyanine - B 2:207 Cyclomicrobuxeine 2:207 Cyclomicrosine 2:207 Cycloneosamandaridin 9:305 Cycloneosamandion 9:305 (1Z,5Z)-l,5-Cyclooctadiene 26:81,88 Cyclo-octanoid terpenes 6:33-36 synthesis of 6:33-36 L-Cyclooligosaccharide 8:359-370 Cycloorbicoside G 25:202 Cycloorbigenin B 25:185,187,202 Cyclooxygenase inhibitor 25:593; 28:16,17 aspirin as 30:594 broussoaurone A as 28:16,17 broussoflavonol F as 28:17 Cyclooxygenase inhibitory activity 26:46,556 ofjenisseensosides A-D 26:46 Cyclooxygenase pathway 25:263, 274,593 Cyclooxygenase/Lipooxygenase 25:615 Cyclooxygenase-2 (COX-2) genes 26:927 Cyclopamine 7:16,17,21,22;21:97; 23:583,563,565,575 structure of 23:583 Cyclopapilosine -D 2:207 Cyclopenta [c] pyran 7:458,459 cis-Cyclopenta [d] pyrimidine-2,4,dione 22:291 Cyclopentadecanones 10:330,331 Cyclopentadiene 2:162,307,308;8:141147,150,153;11:307,308;22:204 Cyclopentane annulation 13:6,16 Cyclopentane ring system 6:6-8,30,31 annulation of 6:6-8,30,31 cis- l,2-Cyclopentanediol 10:324,325 trans- 1,2-Cyclopentanediol 10:324,325 1,2-Cyclopentanediol 8:20 Cyclopentanoid monoterpene alkaloids 7:443,444 Cyclopentanoid natural products 4:581 Cyclopentanoids 8:139 Cyclopentanol 14:647 formation of 14:647
in 6-alkoxy ketones 14:647 ring expansion of 8:245 Cyclopentanone 6:428,429;22:199 1-piperidenines from 6:428,429 Cyclopentanooxazolidine 12:295 Cyclopentendialdehyde 7:465,466 Cyclopentene annulation 13:14 Cyclopentenpolyols 7:475 Cyclopentenyl diene isocyanide acid 21:363 Cyclopentylamine derivative 8:397 (S)-Cyclopentylglycine 13:510,511 Cyclopeptolides 10:280,281 Cyclophellitols 19:351-388 Cyclophosphamide 25:431 Cyclophosphamide treatment 25:447 Cyclopia 7:16 Cyclopiazonic acid 28:119 as calcium uptake inhibitor 28:119 Cyclopic embryo 23:572 Cyclopic lamb 23:567 Cycloposine 7:16,17;23:565 Cycloprodigiosin 8:272 Cyclopropanation 14:489-491 diastereoselective 14:489-491 exo 1:252,253 intramolecular 16:222 of allylic alcohol-acetal 14:490,491 ofdiazo ketones 3:39,40 of ten-membered enones 8:179 of unsaturated acetal 14:490 with Me3S (O)I-NaH 8:186 with oxysulfurane 8:183 cis-Cyclopropane 8:184,185 trans-Cyclopropane 8:183,184 Cyclopropane aldimine 12:287 Cyclopropane methylsteroid 27:470 Cyclopropane ring opening 1:250-253 Cyclopropane- 1,2,3-selenadiazole 9:122,123 Cyclopropanecarbonitrile 12:287 Cyclopropanedicarboxylic acid 10:618 Cyclopropanes 3:288,232,407 Cyclopropanone 8:36 Cyclopropanone sliding reaction 6:37,48
214
(+)-A-9(12)-capnellene from 6:48 in (+)-dactylol formation 6:237 in eight-membered marine compounds 6:37 Cycloproplyalanine 21:297 Cyclopropylimine 1:250,251,296 acid catalysed rearrangement 1:250,251,296 Cyclopropyl ketones 2:168,169 Cyclopropyl-carbinol rearrangement 3:23 Cyclopropylphosphonum salts 12:311 Cycloprotobuxine-C 2:207 Cycloprotobuxine-F 2:207 Cyclopseudohypericin 22:649; 30:607,608 structure of 30:608 Cyclopycnanthoside I 25:198 ~-Cyclopyrethrosin 27:554 Cyclorenierins 25:694 [2+2]-Cycloreversion 15:266 Cycloreversion 4:609 (-)-(2S,3R)-Cyclosarkomycin 8:150,152 D-Cycloserine 26:366 Cyclosieversioside A 25:193 Cyclosleversioside B 25:194 Cyclosieversioside C 25:193 Cyclosieversioside D 25:194 Cyclosieversioside E 25:192 Cyclosieversioside F 25:193 Cyclosieversioside G 25:194 Cyclospongiaqulnone-I 15:299 Cyclo spongiaquinone-II 15:299 Cyclosporine 5:128;21:225,226;22:58, 247,257 Cyclosporine A 10:256-58,299,20:894; 22:245 ;26:486;30:4 Cyclosporine C 21:226 Cyclostellettamines 21:56 Cyclosterol 16:324 Cyclotaxanes 20:3,11,80,100 Cyclotetrapeptides 10:250 Cyclotheonamide A-E 26:1179,1180 Cyclotheonamide B 25:715 Cyclotheonamide E2 26:1180 Cyclotheonamides 25:715 Cyclovirobuxeine-A 2:207 Cyclovirobuxeine-B 2:207 Cyclovirobuxine-D 2:207
Cyclovitamin D3 10:70 Cycloxygenase 25:47 inhibition of 25:47 9[3,19-Cyclo-A(6---~7) steroidal alkaloids 2:207 Cycnomorium songaricum 29:574 Cycopentannulation 1:551,552 Cyctoalpioside B 25:201 Cyerce cristallina 21:317 Cyercenes 21:317 Cylindramide 28:139 cytotoxic activity of 28:139 Cylindricine A and B 25:793 Cylindricines I and J 25:859,860 Cylindricins 25:857,859 Cylindrines F,G and H 25:859,860 Cylindrocarpon olidum 26:471 Cylindrocarpon sp. 27:871 Cylindrocladium ilicicola 21:215 ilicicolin-H from 21:215 Cylindrol B~ 25:790 Cylindrols 24:445-447 bovine brain FPTase activity of 24:446 related compounds 24:445 structures of 24:445 Cylindrospermopsis raciborskii 25:732; 26:352 Cylitol 25:920 [3-Cylodextrin 13:332 Cymbastela coralliophila 25:704 Cymbastela hooperi 25:689,814, 856;28:665 Cymbastela sp. 25:714,768,792,847 Cymbopogan winterianus 21:595 Cymbopogon citratus 28:398 essential oils from 28:398 Cymbopogonflexuosus 14:450,451 eudesm-11-en-4-ols from 14:450 intermedeol from 14:450,451 Cymbopogon nardus 28:398 essential oils from 28:398 p-Cymene 21:585,598,601;25:145 m-Cymene 28:406 acaricidal property of 28:406 Cymicilen 27:483 Cymol 20:13,16 Cynanchum decipiens 22:518 Cynanchum otophyllum 22:518
215
Cynanchum saccatum 22:518 Cynara scholaris 13:660 Cynara scolymus 23:752;25:943 Cynarin 13:660 Cynaropicrin 29:90 activity in NO assay system 29:90 activity in TNFot assay system 29:90 Cyneromycins 26:444,445 Cynidin IdB 25:613 Cynodon dactylon L. Pers. 22:518 for epilepsy and hysteria 22:518 Cynomorium songaricum 29:575 Cypenamine 8:474 Cyperaceae 9:391 ;27:766 Cyperene 23:546 (+)-6-epi-tx-Cyperone 10:408 13-Cyperone 14:406-413 from thujone 14:406-413 synthesis of 14:406-413 trienone from 14:406-413 (-)-7-epi-Cyperone 14:452,453 from (-)-carvone 14:452,453 (+)-intermedeol from 14:452,453 paradisiol from 14:453 Wolff-Kishner reduction of 14:452,453 ~-Cyperone 25:170,171 Cyperus aromaticus 22:399,400 Cyperus esculentus L. 22:518 for epilepsy 22:518 Cyperus iria L. 22:399 Cyperus monophyllus 22:400 Cyperus pilosus 22:400 Cyperus rotundus L. 22:401,518;24:272 for epilepsy 22:518 Cyperus serotinus 22:400 Cyphostemmin A&B 26:567 Cyprinus carpi 27:439;28:564 antitumor activity of 28:564 as diuretic 28:564 for eye fatigue 28:564 Cyproteptadine 26:1063 Cyptanol 20:670 from Salvia napiflia 20:670 [35S]Cysteine 21:322
Cysteine 23:255,468;30:836 (xz-macroglobulin inhibition by 30:836 Cysteine protease falcipain 25:331 Cysteine protease inhibitor 29:592 effects on cysteine protease 29:592 Cysteine proteases 26:800;29:569 aleurain as 29:569 bromelain as 29:569 Ca2+-regulated 29:569 calpains as 29:569 caricain as 29:569 cathepsin B as 29:569 chymopapain as 29:569 ficin as 29:569 from Plasmodium falciparum 29:569 in Alzheimer's disease 29:569 in gastric cancer 29:569 in type 2 diabetes 29:569 inhibition by 29:569 papain-like 29:569 protease actinidin as 29:569 type I pyroglutamyl peptidases as 29:569 Cysteine proteinase 25:375 Cysteine proteinase inhibtor 25:370 Cysteine sulfoxide 25:854 D-Cysteinolic acid 15:76;25:872 Cystic fibrosis 26:1151 Cystobacterfuscus 28:144 Cystodytes 25:894 Cystodytes dellechiajei 10:250 Cystodytes sp. 21:269;25:820;28:638 dehydrokuanoniamine B from 28:638 shermilamine C from 28:638 Cystodytes violatinctus 25:820;28:639 Cystodytin A 23:270 Cystodytin B 23:270 Cystodytins 25:821 Cystodytins A-C 10:250 Cystophora torulosa 9:322 Cystoseira 26:1121 Cystoseira balaerica 20:35 Cystoseira crinita 20:25,28,35 Cystoseira elegans 18:712,713
216
Cystoseira spinosa (var. squarrosa)
9:321 Cytarabin 21:136 Cytidine 5'-triphosphate 27:820 Cytidine diphosphate diacylglycerols 18:433 Cytisine 2:62,63;21:51,91,98,109; 27:276,280 (-)-Cytisine 15:522;26:487;27:281 Cytisus scoparius 15:525 (-)-3,13 a-dihydroxylupanine from 15:525 Cytochalasans 13:107-153 synthesis of 13:107-153 biogenesis of 4:620 Cytochalasin 25:874,875 Cytochalasin (B) bis-tetrahydropyranylether 13:116 Cytochalasin B 10:166;13:116-118,120; 21:96 synthesis of 10:166;13:116118,120 Cytochalasin C 13:148,149 synthesis of 13:148,149 Cytochalasin D 13:107-139 synthesis of 13:107-139 Cytochalasin E 13"107,114 Cytochalasin G 13:130,131 synthesis of 13:130,131 Cytochalasin H 13:125-129,134;15:353 synthesis of 13:125-129,134 Cytochalasin J 15:353 Cytochalasin K 13:107 Cytochalasins 8:213;21:96;24:549 antiviral microbial-derived compound 24:549 synthesis of 8:213 Cytochalasins N 15:353 Cytochalasins O 15:353 Cytochalasins P 15:353 Cytochalasins Q 15:353 Cytochalasins R 15:353 Cytochalasins S 15:353 Cytochrome 7:105 Cytochrome oxidase-inhibiting cyanide 25:513 Cytochrome P450 13:168;27:346 catalyzing aromatic
hydroxylation 5:456 by hydroxylation 27:346 Cytochrome P450 2El 21:654 Cytochrome P450 enzymes 21:654; 27:348 oxidation of 27:348 Cytochrome P-450 inhibitor 4:621 Cytochrome P-450 monooxygenase 25:318,597 Cytochrome P450-dependent monooxygenases 25:413;30:765 inhibition by chlorophyll 30:765 Cytochromes 18:914 Cytokine gene 25:470 Cytokine mRNA 30:771,775 expression in 30:771,775 RT-PCR analysis of 30:771,775 Cytokine production 26:921 ;30:689 inhibitory effect on 30:689 Cytokine receptors 27:825 Cytokine tumour necrosis factor c~ (TNF-ct) 26:916 Cytokine/cell growth factor 30:768 GM-CSF as 30:768 Cytokines 25:463;27:82;30:192,770 as pain mediator 30:192 HODEs induced genesis of 27:82 in mare- -~lians 27:82 neutrophds as 30:192 Cytokinesis-block micronucleus assay 21:642 Cytokinins 4:227-229;7:89,90,94; 20:531 ;25:367,379;26:581,583,584 6-benzylaminopurine (BAP) as 7:90 2,4-dichlorophenoxyacetic acid as 7:90 kinetin (6-furfuryl amino purine) as 7:90 Cytolylic/Cytostatic factors 23:132 Cytolytic activity 30:95 of mouse lymphocytes 30:95 Cytolytic cytostatic factors 23:132 Cytolytic lymphocytes (CTL) 25:273 Cytolytic T cells 25:453 Cytolytic T lymphocytes 25:271 Cytomegalo virus infections 25:431
217 Cytomegalovirus 30:394,404,412 biological properties of 30:404 pathogenetic properties of 30:404 Cytopathic activity 20:442;21:665,744 Cytopathic components 30:397 Cytopathic effect 24:483;30:397 of HIV-1 30:397 of HIV-2 30:397 Cytopathogenicity 15:76 Cytoplasmic guanylate cyclase 25:382 Cytoplasmic inhibitor protein 26:926 Cytoplasmic proteins 28:321 in apoptosis 28:321 Cytoprotective activities 21:655;26:224 Cytosal ascorbate peroxidases 27:736 Cytoseria unsenoides 22:519 Cytosine 19:516 Cytoskeleton 21:96 Cytosolic Ca ++ 30:383 elevation by G-protein 30:383 Cytosolic calcium mobilization 30:339 inhibition of 30:339 Cytosolic dehydrogenase activity 25:423 Cytosolic inositol (tris) phosphate 18:857 Cytosolic PIA2 25:717 Cytosolic sphingosine kinase 25:264 Cytostatic activity 18:775-778;20:796; 21:637;28:146 of eliamid 28:146 Cytostatic effect 26:924 Cytostatic T cells 25:453 Cytotoxic 12:390;24:799,845 against human neurablastoma NB-1 cells 12:390 biological activity 24:799,845 staurosporine 12:390 Cytotoxic action 25:477 of TMB (3,4,5,-trimethoxybenzoy) 25:477 Cytotoxic activity 4:101 ;5:84,342-346, 353 ;21:399,404,634,637,655,675; 23:78,96,172,177,180,186,234,235,2 85,296,299,301,308,313,346,649, 660,679,698,797,800,801; 24:309-318,837;26:216-218,452,470, 485;27:927;28:17,65,217,220,227,
468,470;30:156,589,590,624,691, 692 against KB cell line 30:692 against leukemia cells 23:74,186 demethylsonodione 30:589 of (-)-deoxypodophyllotoxin 30:589 of (-)-hernone 30:590 of (-)-nymphone 30:590 of (-)-yatein 30:590 of (+)-corytuberine 30:589 of (+)-epiaschantin 30:590 of (+)-epimagnolin 30:590 of (+)-epiyangambin 30:590 of (+)-hernovine 30:589 of (+)-laurotetanine 30:589 of (+)-magnoflorine 30:589 of (+)-malekulatine 30:590 of (+)-N- formyldehydroovigerine 30:589 of (+)-N- formylnornantenine 30:589 of (+)-N-formylovigerine 30:589 of (+)-N-hydroxyhernangerine 30:589 of (+)-N-methylhernangerine 30:590 of (+)-ovigerine 30:590 of (+)-ovihernangerine 30:590 of (+)-vateamine-2' [3-N-oxide 30:590 of 15-methoxycarbonyl nagilactone D 28:468 of 15c~-hydroxy-pristimerin 30:692 of 16-hydroxy podolide 28:468 of 1-deoxy-2c~-hydroxyagilactone A 28:468 of 2a-hydroxynagilactone F 28:470 of 3,5-diiodetyramine 23:235 of 3-deoxy-2 cz-hydroxynagilactone E 28:470 of 7-formyldehydrohernangerine 30:589 of 7-formyldehydronornantenine 30:589 of 7-formyldehydroovigerine
218
30:589 of 7-hydroxy-6-methoxy- 1methylisoquinoline 30:589 of 7-oxohernagine 30:590 of 9-methoxycamptothecine 5:84 of Acalycgorgia 5:368,369 of alga 5:342,346 of anacardic acids 30:156 of ansamycin 23:96 of Antiaris toxicaria (Moraceae) 28:220 ofantiarone I 28:227 ofantiarone J 28:220 ofantiarone K 28:220 ofantiarone L 28:220 ofartocarpus flavonoids 28:220 ofartonin A 28:220 ofartonin B 28:220 of artonin E 28:217,227,220 ofartonin H 28:220 ofaulacocarpin A 23:797 ofaulacocarpin B 23:797 of aulacocarpinolide 23:797 ofbetulinic acid 28:17,40 ofbicyclic phloeodictine B 28:688 ofbipinnatins 23:177 ofbroussoflavonol B 28:227 ofbroussoflavonol C 28:227 of camptotheeine 5:84 of celastroloids 23:649 of cembranes 23:180 of cembrones 23" 180 of chaparrin 23:299 of coclenterate 5:342 of cucurbitacin B 28:65 of curcumenes 23:180 of cyclic peptides 4:101,102 of cycloheterophyllin 28:220 of defensins 23:346 of dehydrobruceantin 23:285, 308,313 of dehydrobruceantinol 23:308,313 of doxorubicin 23:299 of eurycomalactone 23:301 of flavonoids 27:927 ofgalanal A 23:801 ofgalanal B 23:801
ofgancaonin R 28:227 of glucarubolone 23:299 ofglyasperin A 28:227 of glycyrol 28:227 ofguaianolides 23:180 of hernandonine 30:589 of hemanymphine 30:589 of heterophyllin 28:220 of holacanthone 23:299,301 ofindaquassin-X 23:296,299 ofinumakilactone A 28:468 ofinumakilactone B 28:468 ofkallilolides 23:180 ofkazinol B 28:227 of Licania genus 28:65 ofLicania heteromorpha 28:65 ofLicania michauxii 28:65 oflicochalcone B 28:227 of licoricidin 28:227 of longilactone 23:301 ofMaytenus amazonica 30:691 of mollusk 5:342 of momsin 28:227 ofnagilactone A 28:468 ofnagilactone B 28:468 ofnagilactone C 28:468 ofnagilactone D 28:468 ofnagilactone E 28:468 ofnagilactone F 28:468 ofnagilactone G 28:468 of N-hydroxyovigerine 30:589 of N-methylcorydaldine 30:589 of N-methylovigerine 30:590 of norartocarpetin 28:227 ofochraceolide A-E 23:698 of Penstemon campanulatus 24:837-838 ofpodolactone E 28:470 ofpseudopterolides 23:180 of samaderine-Y 23:299 of samaderine-Z 23:296,299 of sampsoniones 30:624 of sesquiterpenes 23:180 of sesquiterpenes alkaloids 23:660,679 of sponge 5:342-346,353 of thalifoline 30:590 of tunicate 5:342 of ulithiacyclamide 4:101
219
Cytotoxic agent 2:404,293-303,653; 19:601 ;26:760;30:310 D-aminoacyl-anthraquinone derivatives as 30:310 from Nerium oleander 9:293-303 savinin 13:653 Cytotoxic cardenolide 30:660,662 against KB cell line 30:660 from Crossopetalum gaumeri 30:660,662 Cytotoxic effects 23:531 of resveratrol 23:531 Cytotoxic flavonoids 27:925 Cytotoxic guanidine-alkaloids 25:706 Cytotoxic hydrophilic taxol derivatives 12:221 Cytotoxic peptides 4:83,110 Cytotoxic sesquiterpene alkaloids 23:679 Cytotoxic T cells (CTLS) 24:131; 30:778 Cytotoxic T lymphocytes 26:950 Cytotoxic triterpenes 23:694;30:690 Cytotoxic value 27:930 of flavonoids 27:930 of vinblastine 27:782 Cytotoxicity 5:388;21:134,136,150, 174,257,259,260,262,263,265,267, 269,270,271,273,274,284,311,364, 410,634,643,656,661,690,704,744; 23:96,97,187,218,238,249,250,253, 255,272,274,277,290,292,299,308, 317,701,274 ;24:294,352,740,867; 26:212-213,1185 ;27:94,924,926; 28:118,121 ;30:27,59,226,560,588, 593,596,690 against cancer cell lines 30:588 against marine lymphoma 23:187 against Meth-A 30:59 against uterine carcinoma 30:596 bioassay of 24:867 in COLO-205 (colon carcinoma) 30:690 in KB nasopharynx carcinoma 30:690 of 4'-demethyldeoxypodophyllotoxin 26:213
of (-)-6'-hydroxyyatein 26:212 of (-)-hernone 26:212 of (-)-nymphone 26:212 of (-)-yatein 26:213 of[3-alaninookadaic acid 5:388 of 13-amyrin 23:535 of 8-aminovalcrookadaic acid 5:388 of 7-aminobutyrokadaic acid 5:388 of [3-apopicropodophyllin 26:213 of 4-0-butanoyl-4'-demethyl podo-phyllotoxin 24:740,741 of 5-methoxydehydropodophyllotoxin 26:212 of ailantinol A 23:317 of amarolide 23:299,317 of 3-aminoflavones 27:926 ofamphidinolide B 5:396 of benzopentathiepins 23:238 ofbripiodionen 28:117,118 ofbruceanol C 23:288 ofbruceanol D 23:290,292 ofbruceanol E 23:290,292 of bruceanol F 23:290,292 ofbruceoside-A 23:317 of catechins 27:924 of cephalotaxus alkaloids 24:294 of chaparrin 23:299 of cholistane-3/~,5a,6p-triols 24:352 ofcystodytin A 23:272 ofcystodytin B 23:272 ofcystodytin C 23:272 of cystodytin J 23:272 of dehydro-[3-peltatin methyl ether 26:212 of dehydro-bruceantarin 23:308 of dehydro-bruceantin 23:308 of dehydro-bruceantinol 23:308 of dehydrokuanoniamine B 23:272 of dehydropodophyllotoxin 26:212 of deoxydehydropodophyllotoxin 26:213 of deoxypicropodophyllin 26:213
220
of dercitamide 23:274 of diplamine 23:272 of doxorubicin 23:299 of dysodanthin A 26:212 of dysodanthin B 26:212 of ecteinascidins 23:253,255 of equisetin 28:121 of Etoposide 26:213 of eurycomalactone 23:301 of fatty acid derivatives 23:218 of flavonoids on cancer cell line 27:893 of Ganoderman lucidum 30:59 of glaucarubolone 23:299 ofglycookadaic acid 5:384,385 ofhalichondrin B 5:378,380 ofhalichondrin C 5:380 of holacanthone 23:299 ofhomohalichondrin A 5:380 ofhomohalichondrin B 5:380 of indaquassin B 23:299 of isodeoxypodophyllotoxin 26:213 of isoquinoline alkaloids 30:588 of isoquinolines 30:588 ofkuanoniamine A 23:272 of lamellarins 23:242,245,249, 25O oflignan constituents 30:588 of longilactone 23:301 of macbecin I 23:97 of maytenfolone-A 30:690 of mecbocin I 23:97 of megaphone acetate 26:212 of naphthomycin A 23:66,96 of norhalichondrin A 5:378,380, 383,384 ofokadaic acid 5:384,385,389 of pantherinine 23:272 of penazetidine A 23:194 of quassinoids 23:285-333 of quinones 23:537 ofsamaderine X 23:288,299 ofshermilamine B 23:272 of shinjulactone C 23:317 oftaurookadaic acid 5:388 of theonellamides 26:1185 of mmour necrosis factor 5:387 of varamine A 23:272
of vatdiospyroidol 23:535 of voramine A 23:272 of yadanzioside 23:317 role ofheverlines A-C 30:596 to EL4 cells 30:27 Cytotoxicity assay 21:641 ;30:593 against JB6 cells 30:593 Cytotoxin agents 24:1055,1085 Cytotrienin 23:54 Cytotstatic activity 25:433,434 of Meth A tumor cell antigen 25:444 Cytovaricin 5:607 Cyttaria harioti 5:278;23:127 Czapek-Dox medium 25:154
l(x,25(OH)2D analogue 30:497 in human osteosarcoma 30:497 2D INADEQUATE spectra 9:143-146 1D INADEQUATE spectra 9:145 D-(-)-DIPT 19:490 D-(+)-DIPT 19:445,480,490 D:A-friedo-olean-3,21-dione 7:147,148 D:A-friedo-oleananes 7:150-152 biogenesis of 7:150-152 from Kokoona zeylanica 7:147149 D:B-friedo-oleanane 7:150 D:C-Friedooleanane 22:101 Dl-agonists 21:58 Dl-antagonists 21:68 D ~-receptor 21:18 24-epi-D2 30:490 synthesis of 30:490 1ct,25(OH)zD2 30:494,495 binding affinity of 30:494 bone resorbing activity of 30:495 calcemic effect of 30:495 D2-agonists 21:58 D2-antagonists 21:68 let,25(OH)zD3 30:484,494,495,500 analogues of 30:484 binding affinity of 30:494 bone resorbing activity of 30:495 calcemic activity of 30:484,495 effect on bone maturation 30:484 effect on calcium metabolism
221
regulation 30:484 effect on immune responsiveness 30:484 effect on malignant cell differentiation 30:484 in multifunctional biological responses 30:484 pharmacokinetics parameters of 30:500 use in cancers 30:484 use in immune disorders 30:484 use in psoriasis 30:484 1,25(OH)2D3 calf thymus receptor 30:496 competitive binding to 30:496 lct,25(OH)2D3 metabolites 30:495 D-3-(3,5-Dihydrophenyl) alanine 25:824 D3-receptor 21:18 ltx,25(OH)2D4 30:495,499,500,501,504 bone resorbing activity of 30:495 calcemic effect of 30:495 effect on animal model with osteoporosis 30:499 in rat 30:504 metabolic pathway of 30:504 pharmacokinetics parameters of 30:500 l(x,25(OH)2D4 activity 30:497 affinity of 30:497 bone mobilization of 30:497 on calcium transport 30:497 lo~,25(OH)2D4 drug 30:503 for immune disorders 30:503 for osteoporosis 30:503 for skin diseases 30:503 24-epi-D6 30:490 synthesis of 30:490 D-arabino-hex-2-ulosonate 20:857,859 D-arabino-hex-2-ulosonate sodium salt monohydrates 20:859 (DBU) Diazabicyclo[5.4.0]undec-7-ene 6:126; 127;13:424,425 D-arabitol 9:288 Dacrydium cuprassinum 3:117;13:1922 Dacrydium intermedium 20:619
Dacryhainansterone 29:19 as synthetic ecdysteroid analogues 29:19 Dactomelynes 19:411 Dactylicapnos torulosa 27:177 Dactylocyclines A 29:315 from Dactylosporangium strain ATCC 53693 29:315 stereochemistry of 29:315 sugar moieties of 29:315 Dactylol 3:91-93 synthesis of 3:91-93 from Aplysia dactylomela 6:35 relation to poitediol 6:35 synthesis of 6:36,37 (+)-Dactylol 6:37 cyclopropanone sliding reaction in 6:37 from (+)-africanol 6:37 from tricarbocyclic epoxide 6:37 Dactylomelol 17:8 Dactylopius coccus 20:734 Dactylospongia elegans 25:694 (-)-Dactylosponol 15:297 (-)-Dactylospontriol 15:297 Dactylosporangium ATCC 53693 29:315 Dactylynes 19:411 (-)-Dactylynes 19:411 Dacus cucumis 5:225 2,5-dimethyl-3-, 6-dimetyl pyrazines of 5:225 Dacus cucurbitae 5:225 2,5-dimethyl-3-methylp yrazines of 5:225 methylpyrazines of 5:222 Dacus dorsalis 5:222 2,5-dimethyl-3-methylp yrazines of 5:222 Dacus occfipitalis 5:222,223 2,5-dimethyl-3-ethylpyrazines of 5:222,223 Dacus oleae 4:571,222;14:521,19:131 DAG (diacylglycerol) 27:827-829 DAGO 30:801,802 inhibitory effects of 30:801 DAH 30:444,448,473 precursor of 30:444 stereocontrolled total synthesis of
222
30:473 synthesis of 30:448 4-epi-DAH acetylated esters 30:467 DAH ammonium salt 30:455 by spiroketal glycosides 30:455 Dahlia spp. 29:580 DAHP (3-deoxy-D-arabinoheptulosonate 7-phosphate) 11:183,184;30:420,431,472 in multienzyme system 30:431 structure of 30:420 synthesis of 30:472 DAHP synthetase plasmid 30:431 Daidzein 22:446 Daizein 26:751 Dakaira subovoidea 25:831 ;28:620 6H-anthra[ 1,9-bc] thiophene derivatives of 28:620 Dakin reaction 9:341 (D-Ala,des-Gly2)DYN-A-( 1-11)-NH2 30:809 activity in functional bioassay 30:809 analytical properties of 30:809 Dalbergia hupeana 25:93 Dalbergia parviflora 25:162 Dalbergia stipulacea 29:772 Daldinia concentrica 26:470 Dalea filiciformis 29:581 Daleformis (pterocarpinoid phytoalexin) 29:581 effects on ECE 29:581 from Dalea filiciformis (Fabaceae) 29:581 Daliocarpus dentatus 26:229 (-)-liriorinol B from 26:229 (+)-medioresinol from 26:229 (+)-pinoresinol from 26:229 Dalton's lymphoma ascites 26:303 Damacus carota 25:377,669 Damaliscus dorcas 19:122 Damarane 25:50 ct-Damascenone 13:328 T-Damascenone 14:425 from Rosa damascena 14:425 [3-Damascenone 14:430,431 fromRosa damascena 14:425 from safronitrile 14:430,431
from thujone 14:431,432 synthesis of 14:430,431 Damascones (rose oil ketones) 14:425-431 synthesis of 14:425-431 Damavaricin 21:430;23:54 Damavaricin D 21:435 Damavaricin Fc 23:97 Damiana 13:660 Damirones 25:707 23-(Z)-3,25-dioxo-25-nor-Dammara20,24-diene 30:658 HMBC spectrum of 30:658 Dammaradienol (dammara-20,24-dien313-ol) 29:586 effects on CHY 29:586 Dammarane 22:95;23:692 Dammarane derivatives 2:91-93 Dammarane saponins 24:144,146 Dammarane triterpenoids 2:91-93 Dammarane type saponins 21:651; 23:503 Dammarenediol-I 23:546 Damnacanthal 25:546;26:673,806 c~-Damscone 14:425 fromRosa damascena 14:425 Damsin 1:546 Danaidone 8:223 from Danaus gilippus 8:223 Danaus gilippus 8:223 danaidone from 8:223 Danaus plexippus 21:107 D-and L-2,4-Di-O-benzyl-myo-inositol 18:427 Dandrolasin 17:13 Danishefsky synthesis 12:12,13,15 of mitomycins 13:443 ofavermectin A~a 12:12,13,15 Danishefsky's diene 1:460,474;4:122, 130,132;8:207;13:565;14:18, 636-638;16:474,496,654 Danishefsky's KDO synthesis 30:461 Danishefsky's pyran synthesis 1:460, 407 Danshenol A 22:175 Danshenol B 22:175 Danshensuan B 26:235 3-Dansylamino piperidone 9:549 Dansylation 9:547,549
223
Dansyl-CaM fluorescence 25:544 Dapetes 198 Daphna genkwa 13:660 yuanhuacine from 13:660 Daphnandrine 26:824,826 Daphnane 12:246;25:246 Daphne cannabina 27:833 activator from 27:833 Daphne mezereum 20:22;27:833 activator from 27:833 Daphne odorata 26:465 Daphnetin 7:224;27:847 Daphnetoxin 20:22 Daphniphyllium alkaloid 16:441 synthesis of 16:441 Daphnoretin 25:545 Daphnoretin (4) 27:847 D-arabinose 30:452 D-arabinose derivatives 30:434 methyl dichloroacetate 30:434 D-arabinose-5-phosphate 30:429 irreversible aldol reaction of 30:429 Dartiscin 5:682 Darzens reaction 17:612 Darzens-Nenitzescu condensation 19:235 DAST 19:341 Dasyanthogenin 25:199 Dasycarpidone 1:34,56-58 Dasytricha 2:294 Datisca cannabina 5:678,682 Datiscanin 5:682 Datiscetin 5:678 Datiscoside 5:682 Datumetilin 20:181 Datura aurea 22:742 Datura brugmansia 22:734 Datura candida 22:742 Daturafastuosa L. 22:519,742 for epilepsy 22:519,742 Datura innoxia 11:204;22:742 Datura metel L. 22:519 for epilepsy 22:519 Datura stramonium 20:135;22:742 Datura tatura 20:194 daturataturin A and B from 20:194 Datura. 17:395;21:104,488
Daturadiol 7:164,166 Daturalactone A 20:194,242,246 Daturalactone B 20:194,223,241,246 Daturalactone C 20:180,241 Daturilin 20:181 Dauben-Mincho oxidation 21:714 Daucane diol 21:232 (+)-Daucene 14:356 (-)-Daucene 5:732,734,226 (-)-Daucol 14:356 Daucol 5:721,725,730-732,736,737 Daucus 29:579 Daucus carota W. 5:721,730;22:519; 27:686;29:592 as anticonvulsant agent 22:519 for epilepsy 22:519 Daucus spp. 27:686 Daucyl-d,/-alaninate hydrobromide 5:721 Daunomycin 1:498,371-319,412,474, 475,493;14:474,475;26:802 Daunomycinone 1:500-502;4:321,322, 349;14:24-42 biosynthesis of 11:123 from aklavinone 11:123 synthesis from amino acids 4:345-349 synthesis from hydroxy acids 4:345-349 synthesis of 1:500-502;4:321, 322,349;14:24-42 Daunorubicin 4:317,318,355;14:3; 20:458;21:157,163,165-168,176 L-Daunosamine 1:510-513 synthesis of 1:510-513 3-epi-Daunosamine 4:149 synthesis of 4:149 Daunosamine 4:150;14:4;21:168 synthesis of 4:150 Daunosamine analogues 4:240,241 of adenine 4:240,241 of cytosine 4:240,241 of puromycin 240,241 of thymine 4:240,241 Daurinol 17:335 synthesis of 17:335 Daurisoline 21:72 Davana ether 9:533
224 Davanone 3:58,217,218;7:217; 9:531-533;27:592 Davidiol B&D 26:463,564 Davidsonia pruriens 29:588 Davuriciin D~ 23:404 1,3-Davuriciin T1 23:404 Dawodensin A 15:117,124,131,171 DBU 22:209 DCC-HOSu procedure 6:407,409 2D-COLOC 9:147,151,152 3,5-DCQA 25:942,941 1,5-DCQA 25:944 3,4-3,5-4,5-DCQAs 25:940 1,5-3,4-and 4,5-DCQAs 25:941 DDPM 21:674 DDQ (2,3-dichloro-4,5-dicyanobenzoquinone) 11:156,165;21:735 DDQ oxidation 21:388 DDT 21:110 De novo synthesis 25:128,129,294,300, 329,401,659,661,662 De novo-biosynthesis 25:374 4-Deacetoxy T-2 toxin 9:210 6-Deacetoxy- 14,15-deepoxy-xeniculin 29:103 9-Deacetoxy- 14,15-deepoxyxeniculin 5:369,370 Deacetoxy-3'-chloro-2'-hydroxyarguticinin 5:207 IH-NMR spectrum of 5:207 Deacetoxy-3-chloro-2-hydroxyarguticinin 9:66 12-epi-12-Deacetoxyaplysillin 17:12 Deacetoxycephalosporin C 11:211,212 C-3-hydroxylation of 11:211,212 Deacetoxylakuammiline 9:194,195 10-Deacetyl baccatin III 12:217;25:245 10-Deacetyl cephalomannine 25:245 2 5-Deacetyl-2 5-ep i-hy drox y-rifamycin S 23:56 Deacetyl-8-cyclotulipinolide 27:557 Na-Deacetylaspidospermatine 1:40 Deacetylation 1:10 10-Deacetylbaccatin III 11:3,5,61; 23:490 from Taxus baccata 11:61 6~-Deacetyl-baogongteng A 21:751 28-Deacetylbelamcandal 27:835 10-Deacetyldaphylloside 7:469,470
Deacetyldeformoakuammiline 9:194,195 N-Deacetylisoretuline 1:38,39, 9:183,188 Deacetyllutessine 26:610 Na-Deacetyl-Na methylstrychnobrasiline 26:1064,1066 Deacetylretuline 1:38,39 6-Deacetylsandrasin A 23:624,625 ~H-NMR data of 23:625 ~3C-NMR data of 23:625 3,4-Deacetylsoipecoside 26:115 Na -Deacetylstrychnobrasiline 26:1064-1066 10-Deacetyltaxol 11:61;20:81 ;25:245 7-epi-l O-Deacetyltaxol 20:81 Deacetylvindoline hydrazide 14:808, 863 coupling of 14:808 with 20[3-dihydrocleavamine 14:808 9-Deacetylxenicin 5:370 Deacetyl-[3-cyclo-pyrethrosin 27:555 Deacylgymnemic acid 18:655,656,661 DEAE-Cellulose chromatography 2:392,393,394 N-Dealkylation 27:754 and electron transfer 27:754 O-Dealkylation 27:754 and electron transfer 27:754 Deaminated Neu5Ac analogues 30:427 preparation of 30:427 Deamination 1:681 of (R)-2-aminohexadecanoic acid 1:681 Dean-Stark water separator 19:219 Deazaflavin F420 20:840 Debaryomyces castelli 5:283 Debaryomyces hansenii 5:282,283 Debaryomyces kloeckeri 5:283 Debaryomyces phaffi 5:283 Debaryomyces subglobosus 5:283 Debenzylation 11:253,254;19:110,115; 30:441 Debenzylidenation 12:347 by Hanessian procedure 12:347 Deboronation 11:412,413 Debregeasia salicifolia 29:588 Debromination 4:336,337
225 Debromoaplysiatoxin 18:295,297, 19:219 Debromoeudistomin K 25:816,817 Debromohymemialdisine 25:791 5-Debromooroidin 21:270 (2E,4Z)-2,4-Decadienal 10:151 (2E,4E)-2,4-Decadienal 10:151,155 trans-Decahydro-5,8a-dimethyl- 1,6naphthalenedione derivatives 10:461 Decahydroisoquinolines 12:446 (+)-trans-Decahydroquinoline 219A 19:4,7 Decahydroquinoline-type dartpoison frog synthesis 29:419 by Stereodivergent process 29:419 n-Decane 21:600 ),-Decanoiactone 22:511,537 Decanol 21:589 8-Decanolactone 21:197;22:511,537 (R)-y-Decanolide 13:308,309,315,329 (S)-y-Decanolide 13:311,312 Decanolide 13:312,315 ~/-Decanolide 13:32,310,313,315,328, 332 6-Decapeptides 9:487-489 Decaprenoxanthin 7:355 ;20:596,597 absolute configuration of 7:355; 20:596,597 from Cellulomonas dehydrogenans 7:357 Decarboalkoxylative cyclization 14:720-722 alkaline 14:720-722 indolo-[2,3-c~] quinolizidines from 14:720-722 stereochemical course of 14:720-722 Decarbomethoxy- 15,20,16,17-tetrahydrosecodine 5:124 16-Decarbomethoxy- 19',20'-20'-epivoacamine 5:128 16-Decarbomethoxy- 19',20'dihydrovoacamine 5:124 16'-Decarbomethoxy-20'-deoxyvinblastine 4:30,31
Decarbomethoxycatharanthine 14:870,871 Decarbomethoxydeacetylvinblastine monohydrazide 14:863 from deacetylvindoline hydrazide 14:863 velbanamine from 14:863 Decarbomethoxylation 3:473 with MgC12/DMSO 3:473 with CaClz/DMSO 3:475 16R-Decarbomethoxytacamine 5:125 16S-Decarbomethoxytacamine 5:126 16R, 16'-Decarbomethoxytetrahydrosecamine 5:141,142 16S, 16'-Decarbomethoxytetrahydrosecamine 5:142,143 16-Decarbomethoxyvoacamine 5:125 Decarbonylation 3:308,309 Rh (I)-catalysed 3:308,309 with Wilkinson's catalyst 11:263 with chloro-tris-(triphenyphosphine) rhodium 5:802 Decarbonylation -iminium ion cyclization 4:38,39 Decarboxylase 8:298;21:106 Decarboxylation 16:371 of [3-keto ester 16:371 of anthrones 11:121 of 2-methyl-3-buten-2-yl acetate 11:130 Pd-catalyzed 11:143,144 of vinylogous [3-keto acid 14:678-681 Decarboxylative condensation 11:195 8-Decen-2-1actone 22:511,537 10-Dechlorodysideathiazole 25:890 10-Dechloro-N-methyldysideathiazole 25:890 11-Dechlororebeccamycin 12:366,368 from Saccharothrix aerocolonigenes 12:366,368 L-Decilonitre 19:118 Decilorubicin 19:118 Decinnamoyl taxinine J 11:5 Decipiances 15:263-269 Decitol 4:183 Decoctions 30:704,691 for medicinal purposes 30:704
226
Deconjugation 1:464,465 Deconjugative alkylation 4:38 Decriamide 25:893 Decumbenine 21: 733 Decumbenine B 21:733,734 biological activity of 21:736 synthesis of 21:735 Decumbenine C 21:733,734 Decumbesterone A 25:59 Decursin 23:351 Decyanation 6:431-433 Dedrogyl 9:513 Deepoxyneoxanthin 6:136,143,144 DEET 21:611 20-D eethyl-20- epivinc adifformine 19:109,112 20-Deethyl-3-oxo-20-epivincadifformine 19:110-111 20-Deethyl-3-oxotabersonine 19:112 20-Deethyl-3-oxovincadifformine 19:110-111 20-Deethyl-3-thiooxotabersonine 19:112 16-Deethylapovincamine 19:112 Deethylibophyllidine 9:190 20-Deethyltabersonine 19:112 20-Deethylvincadifformine 19:109,111112 Defence gene activation 25:396 Defence mechanism 23:180 against predation 23:180 Defense proteins 25:370 serine proteinase inhibitor I as 25:370 Defensins 22:75,83 Defluorination 5:453,455,477 of 2-fluroestradiol 5:477,453,455 Degalactosylation 7:55 Deglucosylation 26:110,112 of 7-substituted bakankosine derivative 26:112 of secologanin 26:110 Degradation 9:31,32 of aureol 9:31,32 of enantio-sigmosceptrellin-A 9:28,29 ofgeraniol 7:104,105,116 of nerol 7:105 of c~-pinene 7:106
of S-HPOTE 27:71 of 13S-HPOTE 27:71 Degradation reaction 21:502 Deguelin 28:436 as complex I inhibitor 28:436, 437 Dehomologation 12:95 Dehydration 10:124 with Burgess reagent 10:124 of N-monosubsituted formamides 12:113 of phenyl sulfone derivative 30:486 Dehydrioiridodial 16:290 Dehydro 7- a-hydroxy-tomatidenole (DS-d) 25:318 Dehydroabietic acid 14:685,687-689 abietatriene-7-one from 14:685,687-689 Dehydro-[3-peltatin methyl ether 26:212 cytotoxicity of 26:212 10-Dehydro- 10-deacetyl- 11(15-1 )-abeo baccatin III 20:107 19,20-Dehydro- 10-methoxytalcarpine 13:388 14-Dehydro- 15-phenylsparteine 27:262 structure of 27:262 (+)- 14,15-Dehydro- 16-epi-vincamine 5:126 2-Dehydro- 17[~-isopropyl-2-phenylsparteine 27:264 25-epi-4-Deh ydro-2,3,25,27tetrahydrophysalin A 20:189 3-Dehydro-24-epi-teasterone 25:422, 423 3-Dehydro-24-epi-teasterone-reductase 25:422 2-Dehydro-24-norcholesterol 9:412 26-Dehydro-25-epiaplysterol 9:40 from Petrosia ficiformis 9:40 2-Dehydro-2-phenyl- 17[3methylsparteine 27:264 2-Dehydro- 2-phenylsparte ine 27:260,261 mesomeric form of 27:261 2-phenyl-2-dehydrosparteine salts of 27:260,261
227 9,11-Dehydro-3-deoxy-2-oxa-25hydroxy-vitamin-D3 9:515 9,11-Dehydro-3-deoxy-c~-nor-2-oxa-25hydroxy-vitamin D3 9:515 3-Dehydro-6-deoxoteasterone 25:415 Dehydro-6-hydroxymellein 25:498,499 Dehydro-9,10-aristoteline 9:172 Dehydroabietane 2:402,404 Dehydroabietic acid 15:173;29:99 activity in EBV assay system 29:99 from Rabdosia nervosa 15:173 (+)-Dehydroabietylamine 22:279 1,2-Dehydroacetylretuline 1:38,39 (-)-AS-Dehydroalbine 15:524 from Lupinus termis 15:524 18,19-Dehydro-alloaristoteline 11:319, 320 alloaristoteline from 11:319,320 Dehydroamino acids 16:410 (+)-Dehydroancistrocladine 20:419, 420,426 Dehydro-arachidonic acids 9:568 1,2-Dehydroaspidospermidine 2:370; 14:635,636 Dehydrobromination 11:341,342 Dehydrobruceantarin 23:308 cytotoxicity of 23:308 Dehydrobruceantin 7:374 Dehydrobruceantol 7:374 Dehydrobrucein-B 7:374 Dehydrobrusatol 23:295 (+)-Dehydrocaffeic acid dilactone 26:238 (-)-5,6-Dehydrocamphor 16:144 (+)-5,6-Dehydrocamphor 4:644 7-Dehydrocholesterin (chlolesterol) 9:510,511 7-Dehydrocholesterin reductase 9:512 7-Dehydrocholesterol 5:406 22-Dehydrocholesterol 9:47 7-Dehydrocholesterol (provitamin D3) 9:511,521 7-Dehydrocholesterol-reductase 9:511 18,19-Dehydrocobyrinic acid 9:601 Dehydroconiferyl alcohol 5:497;26:202 11-Dehydrocorticosterone 22:135 (-)-Dehydrocostus 14:368
Dehydrocostus lactone 1:556,559;29:89 activity in AM assay system 29:89 synthesis of 1:556,559 trans-Dehydrocrotonin 29:100 activity in CRG assay system 29:100 Dehydrocurdione 23:825 Dehydrocurvularin 11:193,194 by Alternaria cinerariae 11:193,194 Dehydrocyclospongia quinone-I 15:299 1,2-Dehydrodeacetyl retuline 9:195 1,2,3,4-Dehydrodeoxypodophyllotoxin 30:592 as EBV inhibitor 30:592 11,13-Dehydrodesacetyl matricarin 27:580 Dehydrodesoxypodophyllotoxin 18:553,555 1,2,3,4-Dehydrode soxypodophyl lotoxin 18:557,561 3,4-Dehydrodesoxypodophyllotoxin 18:588 Dehydrodicatechin B4 27:778 from (+)-catechin 27:778 Dehydrodiconiferyl alcohol 5:465,467, 497 Dehydrodigalloyl group 23:397,399 in oligomers 23:399 Dehydroeburiconic acid 25:57 3-Dehydroecdysone 19:634 24-Dehydroechinoside A 7:270 from Actinopyga agassizi 7:270 Dehydroepiandrosterone (DHEA) 24:351-398;25:419 Dehydroepijuvabione 22:387 (-)-10,11-Dehydroepingaione 15:237 5-Dehydroepisterol 25:415 Dehydroerucin 215:481 19,20-Dehydroervatamine 5:124 5,6-Dehydroeurycomalactone 23:301 Dehydrofalcarinone 7:202,222 2-Dehydroferruginol 2:402 Dehydrogeissoschizine 15:486-488 Dehydrogenase enzymes 22:4 Dehydrogenation 2:3,4 in CI(NO) mass spectra 2:3,4 of amines 4:54
228 with CMD 4:85 with DDQ 1:8,9,59 with other oxidants 4:85 with palladium black catalyzed 14:763 with p-toluene sulfinyl chloride 4:54 with selenium reagents 14:440 with sulfur catalysis 14:763 13,18-Dehydroglaucarubinone 7:381 Dehydroglyasperin C 28:228 biological activity of 28:228 22-Dehydrohalitylosides D,D 7:298 from Sphaerodiscus placenta 7:298 Dehydrohernandaline 30:563,594 as platelet aggregation inhibitor 30:594 Dehydroipomeamarone 15:249 Dehydroiridodial 3:136;16:290 from Actinidia polygama Miq. 16:290 Dehydrojuvabione 25:546 5,6-Dehydrokawain 23:808 Dehydroleucodin 29:90 activity in COX assay system 29:90 activity in NFkB assay system 29:90 Dehydroleutodin 27:580 Dehydrologanin 16:294 (+)-5,6-Dehydrolupanine 15:523 from Thermopsis chinensis 15:523 11,12-Dehydromakomakine 11:281,282 (+)-makomakine from 11:281, 282 Dehydromatricaria ester 7:202,203,221 Dehydrometenolic acid 25:57 Dehydromonocrotaline 22:13 Dehydromoracin C 28:210 from moraceous plants 28:210 (-)-ALDehydromultiflorine 15:525 from Lupinus termis 15:525 R-(+)-10,11-Dehydromyoporene 15:229 (-)-Dehydromyoporone 15:229 (-)-10,11-Dehydrongaione 15:237 (E)-8-epi-2,3-Dehydrononactate 18:236
(6S,8R)-(E)-2,3-Dehydrononactate 18:237 Dehydronorglaucine 16:508 Dehydroophioxanthin 15:100;30:526, 527 Dehydrooxoperezinone 5:771,773 Dehydropachymic acid 25:57 Dehydropeptidase- 1 (DHP- 1) 12:145 Dehydropipemonaline 21:379,382 Dehydropodophyllotoxin 18:554; 26:212 cytotoxicity of 26:212 1,2,3,4-Dehydropodophyllotoxin 30:568,592 12-Dehydroporson 26:895 Dehydropreakuammicine 1:31 (-)-20S- 1,2-Dehydropseudoaspidospermidine 5:124 (+)-20R- 1,2-Dehydropseudoaspidospermidine 5:124 3-Dehydroquinate 11:184-186 from 3-deoxy-D-arabinoheptulosonate 7-phosphate 11:184-186 3-Dehydroquinate 23:740 3-Dehydroquinate synthase 11:184,219 Dehydroquinic acid 25:928 1,2-Dehydroreticuline 18:53 1,2-Dehydroreticuline reductase 18:53 1,2-Dehydroreticulinium ion 18:53 Dehydroretronecine 22:13 6,7-Dehydroroyleanone 15:173 from Rabdosia lophanthoides var. gerardiana 15:173 from Rabdosia stracheyi 15:175 Dehydrosalviarin 26:868 Dehydrosalvilimbinol 20:683 from Salvia limbata 20:683 2,3-Dehydrosalvipisone 20:712;26:402 Dehydrosaponin I 25:105 Dehydroschisandrol A 26:245 as PAF-induced inhibitor 26:245 6,7-Dehydroschisandrol A 26:247 Dehydroscoulerine 11:204,205 by S-tetrahydroprotoberberine oxidase 11:204 from scoulerine 11:204,205
229 Dehydrosecodine 14:832 epipandoline from 14:832 pandoline from 14:832 Dehydroshikimate 5:124;11:184,185 3-Dehydroshikimic acid 25:928 Dehydroshowdomycin 10:393 by Wittig reaction 10:393 synthesis of 10:393 Dehydrosoyasaponin I Dehydrosoyasaponin I 21:659;25:97, 104,115,116,118,120 22-Dehydrosterols 21:309 25-Dehydrostichlorogenol 7:272 Dehydrosulfinylation 6:342 19,20-Dehydrotalcarpine 13:411, 427,428 synthesis of 13:411,427,428 3-Dehydroteasteron 18:500;25:415, 422,423 from Distylium racemosum 18:500 from Triticum aestivum 18:500 synthesis of 18:512,513 14,15-Dehydrotetrastachynine 5:129 Dehydrotumulosic acid 25:57 dehydropachymic acid 25:57 16a-hydroxtrametenolic 25:57 pachymic acid 25:57 Dehydroxdycapuvosine 5:124 4'-Dehydroxy-4'-flourotebquine 25:344 Dehydroxyisocapuvosine 5:124 4'-Dehydroxytebuquine 25:344 19,20-Dehydroyohimbine 3:412,415 synthesis of 3:412,415 Dehydroyohimbines 3:399,411,412 Dehydrozaluzanin C 26:371,808,809 Dehydrozingerone 23:798 y-Dehydro-c~-amino acid 11:471,472 synthesis of 11:471,472 1,4-Dehydro-13-1actam 12:159,160,167, 172,173 3-Dehydo-6-deoxoteasterone 25:415 19,20-Dehyrocivetone 8:224 Deinbollia borbonica 22:519 for epilepsy and convulsions 22:519 for convulsions 22:519 for epilepsy 22:519 Deisopropylidenation 4:200,201
Deketalization 14:678,679 Deklamin 9:513 DEL 30:800,814 antinociceptive effects of 30:800 resistance to enzymatic degradation 30:814 DELC 30:816 structural modifications of 30:816 DEL C analogues 30:815 antinociceptive action of 30:815 DEL C peptides 30:814 Delayed COSY spectra 9:151,152 Delayed-type allergy suppressant activity 25:46 ofserotonin agonists 25:46 Delesseria sanguinea 4:712 Delocalised allylic cation 30:547 formation of 30:547 Delonix regia 29:604 Delphinidin (anthocyanidin) 5:646; 23:536,551,742,748 ;29: 582,584 effects on LELA 29:584 effects on MMP 29:582 Delphinin chloride 20:738 Delphinium 20:19;26:868,869,871 Delphinium cardiopetalum 26:868 Delphinium consolida 22:519 Delphinium denudatum Wall 22:519 for epilepsy 22:519 Delta opioid receptor 30:799,800 role in analgesia 30:799 Delta receptors 22:24 Deltorphin B 30:801,804,807,817 activity in RJ bioassay 30:807 agonist activity of 30:817 antinociception activity of 30:804 8-selective opioid agonist 30:817 Deltorphin C 30:813 pharmacological activity of 30:813 Deltorphin II 30:810 activity in Tail flick test 30:810 Deltorphins 30:799,801,814 as 8 agonist 30:799 from frog skin 30:801 ct-Demascone 19:137
230 DeMayo reaction 3:74,75,102,103 (+)-4-Demercuration 1:671,672 with sodium borohydride 1:671,672 Demercuration 1:671,672 with sodium borohydride 1:671,672 4 '- O-Demethyldehdropodophyllotoxin 26:227 antifungal activity of 26:22 6-Demethoxy acronycine 20:795 4-Demethoxy anthracyclinones 14:10 4-Demethoxy daunomycinone 14:17 Na-Demethoxy- 11-methoxy-(19Rhydroxy-gelselselegine 15:513 11-Demethoxy- 12-hydroxymyrtoidine 26:1053 4-Demethoxy- 1-O-methyl daunomycinone 14:5 4 '-D emethoxy-3 ',4 '-methylenedioxymethylrocaglate 26:203 4 '-D emethoxy- 3 ',4 '-methylenedioxy rocaglaol 26:203 4-Demethoxy-6-desoxyadriamycinones 14:8 4-Demethoxy-7-deoxydaunomycinone 1:507,508 7-Demethoxy-7-deoxydaunomycinone 4:342,343 4-Demethoxy-7- O-methyl daunomycinone 14:5 4-Demethoxy-9-deacetyl-9-(hydroxymethyl) daunomycinone 14:12 4-Demethoxyadriamycin 4:317 (+)-Demethoxyaspidospermine 19:143 16'-Demethoxycarbonyl-16'-epideoxyvinblastine 14:850-852 synthesis of 14:850-852 Demethoxycarbonylation 10:308,309 by Welch procedure 10:308,309 Demethoxycarbonyldeoxyvinblastine 5:183,184 synthesis of 5:183,184 12-Demethoxycylindrocarpidine 5:124 4-Demethoxydaunomycin 1:501,505510;4:319,320 synthesis of 1:501,505510;4:319,320,323,324,334, 335
Demethoxydaunomycinone 4:319,320 synthesis of 4:319,320 Demethoxydeoxodihydrocolchicine 3:290 synthesis of 3:290 3-Demethoxyerythratidinone 3:479 synthesis of 3:479 (+)-3-Demethoxyerythratidinone 8:270272 synthesis of 8:270-272 1-Demethoxyfeudomycinone 4:346,347 enantioselective synthesis of 4:346,347 Na-Demethoxyhumantenirine 15:494,495 10-Demethoxykopsidasinine 5:5254;9:186-189 Demethoxykopsidasinine 9:188,189 11-Demethoxymyrtoidine 26:1053 (-)- 12-Demethoxy-N(1)-acetylcyclindrocarine 19:112 12-Demethoxy-N(1)-acetylcyclindrocarine 19:115 Na-Demethoxyrankinidine 15:496 from Gelsemium elegans 15:496 12-Demethoxytabernulosine 5:127 Demethoxyyangonin 22:529,541 4'-Demethycpipodophyllotoxin 26:193 (-)-Nb-Demethyl alstogustine N-oxide 9:190 7-O-Demethyl chelerythrine 14:783 7-O-Demethyl dihydrochelerythrine 14:780,781 Demethyl frutescin 9:317 7-O-Demethyl oxychelerythrine 14:783,784 7,8-demethylene sanguinarine from 14:783,784 N-methyl decarine from 14:783,784 Demethyl zeylasteone 7:147,148 Demethyl zeylasteral 7:147-149 N-Demethyl-16-epi-accedine 5:127 Demethyl-2',4'-bis-O-(2-methoxy ethoxy methyl)-7-con-O-3'-N-methylnogarol 14:88 3'-N-Demethyl-2'-4-b is-O-(2-me tho xy ethoxymethyl)-7,8 dihydronogarene 14:87
231 (-)-9-Demethyl-7,9-dimethoxynogarene 14:82 9-Demethyl-9-hydroxy-7-methoxynogarene 14:82 Nb-Demethylalstophylline oxindole 5:159-161;9:196,197 (+)-Demethylaspidospermidine 5:127 Demethylated gardenin A (5,6,7,8,3',4', 5'-nonahydroxyflavone) 29:572 effects on HIV- 1 protease 29:572 Demethylation 1:8,9 O-Demethylbuchenavianine 21:133,134 N4-Demethylcapuvosine 5:124 11-Demethylconoduramine 5:129 Demethylcryptoj aponol 20:666 from Salvia montbretii 20:666 4'-Demethyldeoxypodophyllotoxin 26:213 cytotoxicity of 26:213 4-Demethyldesoxypodophyllotoxin 5:480-484,488 Demethyldihydrokamebacetal A 15:135 (-)-Nb-Demethylechitamine 9:183,184 5-Demethylene bicyclomycin 12:75,76 synthesis of 12:75,76 7,8-Demethylene sanguinarine 14:783, 784 5-Demethylene-6-deoxy bicyclomycin 12:75,76 synthesis of 12:75,76 6,7-Demethylenedeoxypodophyllotoxin 30:568,592 as EBV inhibitor 30:592 Demethylenepodophyllotoxin dimethyl ether 18:597 3-Demethylgorgosterol 9:372 from Gorgoniaflabellum 9:37 from Gorgonia ventilina 9:37 9-O-Demethylhomolycorine 26:619 13-Demethylisodysidenin 25:889,890; 28:666 Demethylmoracin I 28:18 as aromatase inhibitor 28:17 Na-Demethyl-Na-formylleurosine 14:818,819 O-Demethylpalosine 5:127 5-O-Demethyl-paxanthonin 30:620 structure of 30:620
Demethylpeceyline 5:149-151 4'-Demethylpodophyllotoxin 5:475, 477,479,480-482,488,493 ;26:156, 157,192,210,214 N-Demethylrohitukine 3'-acetate 21 : 141 Demethylsonodione 30:570,589 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:589 high-resolution electron impact mass spectrometry (HREIMS) of 30:570 ~H-NMR spectrum of 30:570 IR spectrum of 30:570 molecular formula of 30:570 UV spectrum of 30:570 (___)-6-Demethylstatine 13:514 synthesis of 13:514 N4-Demethyltabernamine 5:123 N4-Demethylvoacamine 5:128 Demethylyatein 5:488;26:157 4'-Demethylyatein 26:192 Demethylzelasteral 5:744-746 Demethylzeylastrone 5:744-746 Demissidine 7:23;25:536 22R,25S-Demissidine 7:19-21 Demodex genus 28:410 Demospongic acid 25:721 Dendrilla cactos 23:246 Dendrimedric peptide 25:336 Dendrimeric multiple antigenic peptides 25:335 Dendroamides 25:716 Dendrobaena clujensis 30:828 from Lumbricidae family 30:828 Dendrobates alkaloids synthesis 29:433-436 aldehydes synthesis in 29:435 aldol-type cyclization reaction in 29:436 alkyl group installation in 29:43 decahydroquinoline type of 29:433 stereochemical course of 29:434 Dendrobates auratus 27:243 Dendrobates histrionicus 11:294 (+)-indolizidine from 11:294
232
Dendrobates pumilio 12:294;19:4; 27:242;29:439 panamanian population of 19:4 pumiliotoxin B from 12:294 Dendrobates speciosus 11:266;12:294 indolizidines from 11:266 N-oxides of allopumiliotoxin 267 A from 12:294 N-oxides of pumiliotoxin 323 A from 12:294 Dendrobates tricolor 12:294 pumiliotoxin 251 D from 12:294 Dendrobatid toxin 1:286,287 synthesis of 1:286,287 Dendrobatidae 11:244,294;12:294 (-)-Dendrobine 16:435 synthesis of 16:435 Dendrobium crepidatum 12:285 crepidamine from 12:285 crepidine from 12:285 dendrocrepine from 12:285 Dendrocotonus brevicomis 11:413 exo-brevicomin from 11:413 Dendrocrepine 12:277,285,286 Dendroctonus pseudotsugae 22:388 Dendrodoa grossularia 5:412;10:245; 23:257,260;28:633 dendrodoine from 28:633 Dendrodoine 5:412;23:257 cytotoxic activity of 5:412 Dendrodoris grandiflora 17:28 Dendrodoris limbata 17:28 Dendroibatidae 19:3 Dendroid-test method 13:233,234 Dendrolasin 1:666 cyclization of 1:666 Dendropanax trifidus 2:98-103 dendropanoxide from 2:98-103 Dendropanoxide 2:98-103,164,165 Dendrostilbella 21:233 Dendryphiella salina 10:152 Dendryphiellin A 10:149,152 Dendryphion sp. 27:871 Dennstaedtia hirsutu 26:111 Dennstaedtia scabra 26:722 De-N-protection 11:270 via hydrogenolysis 11:270 Densitometry 9:453
Dental surgery 30:192 use of non-steroidal antiinflammatory drugs (N SAIDs) 30:192 use of prostaglandin inhibitors 30:192 Dentatin A 7:232;27:551 Dentatin B 7:230 Denticulatin 5:211,212 Denticulatin A and B 17:24 antimicrobial activity of 17:24 Dentroctonus brevicomin 19:126 Denudatin 26:240 antifeeding activity of 8:160 as PAF-induced inhibitor 26:240 Denudatin B 26:233 De-O-acetylation 14:230,232 De-O-benzylation 12:37,38,52 Deoxdehydropodophyllotoxin 26:194 Deoxmannojirimycin 10:527 13-Deoxo- 13et-acetyloxy- 1-deoxy-nortaxine B 20:80 13-Deoxo- 13ot-acetyloxy- 1-deoxytaxine B 20:80 13-Deoxo-13c~-acetyloxytaxine B 20:80 6-Deoxo-24-epicastasterone 18:503,514 6-Deoxo-28-norcastasterone 18:507 9(R)-9-Deoxo-9-dimethyl-aminoerythromycin A 13:182 6-Deoxocastasteron 18:503 6-Deoxocastasterone 25:415,424 C6 oxidation of 25:415,424 11-Deoxoglycyrrhetinic acid 21:656 11-Deoxoglycyrrhetol 21:656 (-)-Deoxoprosopine 12:475 (+)-Deoxoprosopinine 13:482 Deoxosarcophines 21:280,281 Deoxoscalarin 17:10 6-Deoxoteasterone 25:415 3-Deoxotyphasterol 25:415 5-Deoxy analogue 27:842 of quercetin 27:842 11-Deoxy anthracyclinone 14:49 11-Deoxy daunomycinone 14:472 (-)-7-Deoxy daunomycinone 14:493, 494 synthesis of 14:493,494
233
Deoxy PDE-I 3:355 synthesis of 3:355 Deoxy PDE-II 3:355 synthesis of 3:355 Deoxy PTX 251H alkaloid 27:247-249 structure of 27:249 2-Deoxy [3-arabino pyranosyl cyanides 10:354 2-Deoxy [3-glucose 7:59 3-Deoxy- 1,2,5,6-di- O-isopropylidene-3C-methyl-c~-D-gluco furanose 10:435,436 3-Deoxy-l,2:5,6-di-O-isopropylideneD-xylo-hexofuranose 14:172 3-Deoxy-l,2:5,6-di-O-isopropylidene-otD-ribo-hexofuranose 14:154,155, 157,166-171 1'-Deoxy- 1'-fluoro-ABA 27:334 biological activity of 27:334 9,11-Deoxy- 11-methyl-prostaglandins 7:481 Deoxy- 15(15S')-20'-'-14:814,815 hydroxyleurosidine 14:814,815 acetyl derivative of 14:814,815 20'-deoxyleurosidine from 14:814,815 20'-deoxy- 15'-oxoleurosidine from 14:814,815 from anhydrovinblastine 14:814,815 Moffat oxidation of 14:814,815 thioxobenzoate derivative of 14:814,815 (15R')-20'-Deoxy- 15'-hydroxyleurosidine 14:814,815 acetylderivative of 14:814,815 from 20'-deoxy- 15'oxoleurosidine 14:814,815 20'-Deoxy- 15'-oxoleurosidine 14:814, 815 (15'R)-20'-deoxy- 15'-hydroxyleurosidine from 14:814,815 20'-deoxy- 15'-oxovinblastine from 14:814,815 from (15'S)-20'-deoxy- 15'hydroxy leurosidine 14:814,815 20'-Deoxy- 15'-oxovinblastine 14:814, 815
from 20'-deoxy- 15'oxoleurosidine 14:814,815 ( 15'R)- 15'-hydroxy-20'deoxyvinblastine from 14:814,815 12-Deoxy- 16-epi-acetoxyscalarafuran 6:122,123 synthesis of 6:122,123 2-Deoxy- 1-hydroxysugars 11:141 3-Deoxy- 1a-25-dihydroxyvitamin D3 10:70 synthesis of 10:70 Deoxy-24-epibrassinolide 18:50722-Deoxy-2-desmethlene bicyclomycin 12:87 synthesis of 12:87 2-Deoxy-2-fluoro-~-D-glucopyranoside 7:64 as [3-glucosidase inhibitor 7:64 2-deoxy-2-fluoroglucosyl fluorides 7:64 3-Deoxy-2-keto acids 30:423 formation of 30:423 3-Deoxy-2-oxa-25-hydroxy-vitamin D3 9:515,516 2-Deoxy-2-phosphinyl-D-tetritol 6:357 3-Deoxy-2-ulosonic acid 30:419,420, 434,460 stereoselective synthesis of 30:434 3-Deoxy-2-ulosonic acid 30:419,420, 434,460 family of 30:419 from carbohydrate precursors 30:460 structure of 30:420 1-Deoxy-2~3,3[3-epoxy nagilactone A 28:480 anti-feedant activity of 28:480 Deoxy-3- C-hydroxymethyl-13-Dglucopyranosyl 9-3-adenine 4:255 3-Deoxy-3-fluoro-D-myo-inositol 18:439 3-Deoxy-3-fluoro-sucrose 7:69 11-Deoxy-4-demethoxydaunomycinone 1:501 3-Deo xy-4- metho xy-D-manno-D-gluc ooctulosonic acids 30:450
234 4-Deoxy-4-phosphinyl-D-ribofuranoses 6:363-365 5-Deoxy-5-(alkylphosphinyl)-Dxylopyranoses 6:368 3-[ 5-Deoxy- 5(dimethylar sinoyl)-fl-Dribofuranosyloxy]-2-hydroxypropene-l-sulfonic acid 25:867 5-Deoxy-5-(ethylphosphinyl)-Lidopyranoses 6:373 5-Deoxy-5-(hydroxyphosphinyl)-Dglucopyranoses 6:370,371 5-Deoxy-5-(hydroxyphosphinyl)-Dmannopyranoses 6:374 5-Deoxy-5-(phenylphosphinyl))-Dxylopyranoses 6:368 5-Deoxy-5-(phenylphosphinyl)-Lfucosamine 6:369 from 2-azido-D-arabinohexofuranose 6:369 6-Deoxy-5-enohexopyranoside 10:510 Ferrier reaction of 10:510 5-Deoxy-5-phosphinothioyl-Dxylopyranoes 6:374,375 5-Deoxy-5-phosphinyl-Dglucopyranoses 6:369-372 5-Deoxy-5-phosphinyl-Dmannopyranoses 6:373,374 5-Deoxy-5-phosphinyl-D-ribopyranoses 6:368 5-Deoxy-5-phosphinyl-D-xylopyranoses 6:374,375 5-Deoxy-5-phosphinyl-L-idopyranoses 6:373 6-Deoxy-6-[(ethoxy) alkyl phosphinyl]D-glucopy-ranose 6:377
(+)- l-Deoxy-6-8-Di-epi-
castanospermine 12:350
(+)- 1-Deoxy-6-8a-Di-epi-
castanospermine 12:350 6-Deoxy-6-cobalt(III)-dimethylglyoximatopyridine 30:449 photolysis of 30:449 (+)-7- Deoxy-6-epi-castanospermJne 12:276
(-)- 1-Deoxy-6-epi-castanospermJne 12:350
7-Deoxy-6-epi-castanospermine 27:517 (-)-6-Deoxy-6-fluorocastonospermine 1-Deoxynojirimycin 12:332
6-Deoxy-6-fluoro-sucrose 7:69 as competitive inhibitors 7:69 3-Deoxy-7-phospho-D-arabinoheptulosonic acid 25:928 1-Deoxy-8-epi-ivangustin 7:214 from Artemisia pectinata 7:214 l'-Deoxy-abscisic acid 27:334 2'-Deoxyadenosine 10:592,593 3'-Deoxyadenosine (cordycepin) 10:592,593 11-Deoxyadriamycin 1:498 3'-Deoxy-aminoglycoside antibiotic 14:144-147 6-Deoxyandalusol 25:250 1-Deoxyanthracycline 14:481 Deoxyartemisinin 22:154 10-Deoxyaucubin 7:481 Deoxybouvardin 10:640-642;24:306 synthesis of 10:640-642 Deoxybouvardin methyl ether 10:640642 synthesis of 10:640-642 15-Deoxybruceolide 11:79,80,85,86 bmceantin from 11:79,80,85,86 1-Deoxy-castanosperine 12:347 (+)-6-Deoxycastanospermine 12:337, 338 synthesis of 12:337,338 (-)-6-Deoxy-castanospermine 12:346 2-Deoxychamaedroxide 23:609,610 3C-NMR data of 23: 610 ~H-NMR data of 23:610 Deoxycholate 9:565 2-Deoxycrustecdysone 19:466 8-Deoxycumambrin B 27:577 4-Deoxy-D,L-xylo-hexopyranose 14:178 synthesis of 14:178
6-Deoxy-D-altro-heptop yranoses
11:429 6-Deoxy-D-altroheptose 4:195 synthesis of 4:195 11-Deoxydanucomycinone 3:448,449 synthesis of 3:448,449 10-Deoxydaphylloside 7:470,471 3-Deoxy-D-arabino-2-heptulosonic acid 7-phosphate (DAHP) synthetase 30:424 structure of 30:424
235 3-Deoxy-D-arabino-2-heptulosonic acid methyl ester 30:434 3-Deo x y-D-arab ino-2-heptulosoni c acid-7-phosphate 30:431 from phosphoenolpyruvate and D-erythrose 4-phosphate 30:431 5-Deoxy-D-arabino-heptulosonate-7phosphate (DAHP) synthase 11:183,184 3-Deoxy-D-arabino-heptulosonic acid 7-phosphate 30:472 synthesis of 30:472 3-Deoxy-D-arabino-heptulosunate 7phosphate (DAHP) 740 3-Deo x y-D-arab ino-hexop yranose 14:148 3-Deoxy-D-arabino-hexose 14:143 2-Deoxy-D-arabino-hexose 14:176,177 asymmetric synthesis of 14:176,177 4-Deoxy-D-arabiono-hexose 14:143 11-Deoxydaunomycin 1:498 11-Deoxydaunomycinone 1:500,501 chiral synthesis 4:329,330 enantioselective synthesis of 1:596 synthesis of 1:500,501;4:327 7-Deoxydaunomycinone 3:449,450 synthesis of 3:449,450 3-Deoxydebromoaplysiatoxin 18:295 Deoxydehydropodophyllotoxin 26:213 cytotoxicity of 26:213 3-Deoxy-D-erythro-hexulosonic acid 30:437 by non-chelate-controlled process 30:437 3-Deoxy-D-e~ythro-hexulosonic acid 30:437 by non chelate-controlled process 30:437 1-Deoxy-D-galacto-heptulose 7:60 2-Deoxy-D-glucose 15:435 3-Deoxy-D-glycero -D-galacto-2nonulosonic acid 11:429,467 3-Deo x y-D-glyc ero-D-galacto-2nonulosonic acid (KDN) 30:420 3-Deoxy-D-glycero-D-galactononulosonic acid 30:427
preparation of 30:427 3-Deo x y-D-glyc ero-D-ga la c tononulosonic acid 30:427 preparation of 30:427 7-Deoxy-D-glycero-D-glucoheptose 26:373 4-Deoxy-D-lyxo-hexopyranose 14:176 asymmetric synthesis of 14:176 3-Deoxy-D-lyxo-hexose 14:143 4-Deoxy-D-lyxo-hexose 14:158 synthesis of 14:158 3-Deoxy-D-manno-2-octulosonic acid
11:429,440,441,464
3-Deoxy-D-manno-2-octulosonic acid 20:857 6-Deox y-D-manno-heptop yrano ses 11:429 6-Deoxy-D-mannoheptose 4:195 3-Deoxy-D-manno-octulosonate (KDO) aldolase 30:424 structure of 30:424 3-Deoxy-D-manno-octulosonate 8phosphate (KDO 8-P) synthetase 30:424 structure of 30:424 3-Deoxy-D-manno-octulosonic acid 30:419 2-Deoxy-D-ribofuranose 6:361 3-Deoxy-D-ribo-heptulosonic acid 30:437 3-Deoxy-D-ribo-hexofuranose 14:159 3-Deoxy-D-ribo-hexofuranoside 14:164 synthesis of 14:164 3-Deoxy-D-ribo-hexopyranose 14:148 4-Deo x y- D-ribo-he x op yranos ide 14:164 synthesis of 14:164 4-Deoxy-D-ribo-hexose 14:143,174 3-Deoxy-D-ribo-hexose 14:176,177 asymmetric synthesis of 14:176,177 3-Deoxy-D-ribo-hexose derivative 14:163 synthesis of 14:163 3-Deoxy-D-xylo-hexop yranose derivative 14:164,165 from methyl 13-D-galactopyranoside 14:164,165 4-Deoxy-D-xylo-hexose 14:143,147
236 3-Deoxy-D-xylo-hexose 14:143 9-Deoxyerythromycin A 13:175,176 6-Deoxyerythronolide B synthase 22:265 2-Deoxy-galactose 7:59 1-Deoxy-galactostatin 10:543 Deoxygalactostatin 7:41 Deoxygenation 1:391,392 with AIBN 19:516 with PBr3 1:391,392 of D-glucose 11:219 by zinc-copper couple 4:424 by zinc-dust 4:424 in steroid moiety synthesis 30:486 of ascorbic acid 4:420-423 of tert-alcohol 19:516 with Bu3SnH 19:516 with PBr3 1:391,392 12,13-Deoxygenation 6:234 of verrucarol 6:234 Deoxygeniposide 7:470 Deoxyglycyrrhetol 25:58 Deoxygomisin A 26:197,256 9-Deoxygoniopypyrone 19:463,19:497 5-Deoxygoniopypyrone 9:394 2'-Deoxyguanosine 8:377,378 Deoxyguanosine 8:388-392 Deoxyhemoglobin 26:986 3-Deoxy-hexoaldoses 14:144 4-Deoxy-hexoaldoses 14:144 2-Deoxyhexopyranosyl purimidines 4:229-232 2-Deoxyhexopyranosyl purines 4:229232 (6-Deoxyhexopyranosyl) adenines 4:232,233 3-Deoxy-hexoses 14:143-200 synthesis of 14:143-200 4-Deoxy-hexoses 14:143-200 synthesis of 14:143-200 Deoxyiodo-nucleosides 4:225 14-Deoxyisoamijiol 10:182 3'-Deoxykanamycin A 14:144,145 synthesis of 14:144,145 3'-Deoxykanamycin C 14:186 2-Deoxy-KDO 30:456 hydrogenation in 30:456 transformation of 30:456
2-Deoxy-KDO synthesis 30:470 concept of 30:470 (+)-5-Deoxykievitone 4:378,379 14-Deoxylactucin 29:89 activity in CRO assay system 29:89 Deoxylapachol 29:736 biosynthesis of 29:736 20'-Deoxyleurosidine 14:812 catharinine from 14:812 from anhydrovinblastine 14:871 oxidation of 14:812 3'-oxo-20'-deoxyleurosidine from 14:812 vincristine derivative from 14:818,819 20'-Deoxyleurosidine-N-oxide 14:872,873 5',6'-seco derivatives of 14:872,873 6-epi-7-Deoxylincosamine 11:446 4-Deoxy-lyxo-hexose 14:175 3-Deoxy-magellanol 18:745 4-Deoxy-magellanol 18:745 6-Deoxy-magellanol 18:745 5-epi-2-Deoxymakisterone A 19:468 3-Deoxymaltose derivative 14:163 from 3-chloro-3-deoxy-allo derivative 14:163 Deoxymannojirimycin 7:15,41,42; 10:528-538,540-542 chemico-enzymatic synthesis of 10:541 from Lonchocarpus costaricensis 10:538 from Lonchocarpus sericeus 10:538 from Omphalea dianadra L 10:539 from Streptomyces lavendulae 10:539 golgi c~-mannodiase I,II inhibitor of 10:539 golgi ~-mannosidase I inhibitor of 10:539 intramolecular aminomercuration of 10:540 synthesis of 10:528-538,540-542
237 ~-mannosidase inhibition by 7:15,41,42;10:539 [3-mannosidase inhibitor of 10:539 (+)-Deoxymannoj irimycin 18:347 3-Deoxy-maytol 18:745 5-Deoxymyricanon 17:371 18-Deoxynargenicin 17:298,301 synthesis of 17:298,301 Deoxynivalenol 13:519,538 4-Deoxynivalenol 6:221,224,225,243 Deoxynivalenol (vomitoxin) 6:230,231, 237,240-242;9:204-207,215,216 7-Deoxynogarol 14:47,78,79 (+)-7-Deoxynogarol 14:68-72 9-epi-7-Deoxynogarol 14:78 Deoxynojirimycin 7:14,15,41,42 1-Deoxynoj irimycin (1,5-dideoxy- 1,5imino-D-glucitol) 11:267;12:332 Deoxynucleoside-3-phosphorothioamidates 13:271 3-Deoxynucleosides 4:232 synthesis of 4:232 6-Deoxynucleosides 4:232 synthesis of 4:232 Deoxynucleosides 8:373 Deoxyparguerol acetate 25:788 12-Deoxyphorbol- 13-O-phenylacetate20-acetate 27:830 2-Deoxyphysalolactone 20:223 Deoxypicropodophyllin 26:213 cytotoxicity of 26:213 Deoxypodophyllin 26:193 (-)-Deoxypodophyllotoxin 24:767 synthesis of 24:767 Deoxypodophyllotoxin 26:167,214,215, 216 (-)-Deoxypodophyllotoxin 26:218; 30:568,588,589,595 Deoxypodophyllotoxin (anthricin) 26:193 (-)-Deoxypodorhizone 26:192,215,216 11-Deoxyprostanoids 1:639,640 2-Deoxyribose 6:337 8-Deoxyrifamycin W 23:62 3-Deoxyrosaranolide 11:164 synthesis of 11:164
(+)- 12-Deoxy-scalaradial 6:58,125-129 by Diels-Alder reaction 6:58 synthesis of 6:58,125-129 2-Deoxy-scyllo-inosose 11:217-219 2-deoxystreptamine from 11:217-219 4-Deoxysiastatin B 16:98 Deoxysikkimotoxin 24:767 asymmetric synthesis of 24:768 synthesis of 24:767 3-Deoxysilychristin 26:255 5-Deoxystansioside 7:462,463 2-Deoxystreptamine 11:217,218 from 2-deoxy-scyllo-inosose 11:217,218 14-Deoxystypodiol 6:55 from stypodiolmethyl ether 6:55 synthesis of 6:55 (-)-8-Deoxyswainsonine 12:304,332 14-Deoxy-taondiol methyl ether 6:55 from (+)-manool 6:55 synthesis of 6:55 Deoxytedanolide 19:558 antitumor activity of 19:558 3-Deoxytetrangulol 11:135 Deoxythymidine kinase 30:395 Deoxytrimethylbrazilone (B) 20:777 4-Deoxytromidioside 7:302 2-Deoxy-ulosonic acid analogues 30:467 for synthesis 30:467 3-Deoxy-ulosonic acids 30:435,451 construction of 30:451 synthesis of 30:435 20'-Deoxyvinblastine 14:863,864,871 16'-epi-Deoxyvinblastine 14:870,871
16'-epi-20'-epi-Deoxyvinblastine
14:870,871 from 15,20S-dihydrocatharanthine N-oxide 14:870,871 Deoxyxylulose 25:130
3-Deoxy-c~-D-arabino-2-heptulosonic acid (DHA) 30:420,439 from 1,4-cyclic sulfate and Darabinose 30:439 preparation of 30:439
3-Deoxy-ot-D-arabino-2-heptulosonic
acid-7-phosphate (DAHP) 30:420
238 3 -Deo x y-o~-D-a ra b ino-he x op yranos i de
derivative 14:156 3-Deo x y-(x-D-arab ino-he x op yranos yl-3deoxy-et-D-arabino- hexopyranoside
14:148
3 -Deo x y-et-D-a ra b ino-he x op yranos yl-
(x-D-glucopyranoside 14:148 6-Deoxy-c~-D-galactohexopyranosyl bromide 14:151 [2-Deoxy-(z-D-glyc-2-enopyranosyl] arenes 10:352,353 1-(2-D e oxy- c~-D-rib o-he xopyrano syl) cytosine cis-principle 4:586,587 endo-rule 4:587 in biogenesis 4:615-617 intermolecular 4:587-595 intramolecular 4:595-603 inverse electron demand 4:579, 580,604,605 lysergic acid by 4:504,605 manaomycin A by 4:591-593, 609 mechanism of 4:579,580 monomorine I by 4:606 nanaomycin d by 4:591-593 nepetalactone by 4:604,605 of acylnitroso 4:606 oxazoles in 4:604 palitantin by 4:588-590 prostaglandin by 4:607 pumiliotoxin by 4:584,585 regiochemistry of 4:584-586 retro 4:609-615 solanapyrone 4:598,599 stereochemistry of 4:586,587 stereochemistry of cycloaddition 4:122,123 terramycin 4:609 tetrazines in 4:604 triazines in 4:604 triquinanes by 4:588 vemolepin by 4:584,585 volume of activation 4:112 with heterodiene systems 4:583 with ketenacetals 4:357 with modified cyclohexadienes 4:583 with N-sulfinyl dienophile 4:356
with o-quinodemethone 4:583, 584 with a-amino aldehydes 4:120 [3-santalene by 4:607,608 2-Deoxy-o~-D-ribo-hexopyranosyl-2deoxy-ot-D-ribo-hexop yranoside
14:148 2-Deo x y-cx-D-ribo-he x op yranos yl-o~-D-
glucopyranoside 14:148 3-Deo x y-ot-D-xylo-he xop yranos i de
14:169 2-Deoxy-c~-glucose 7:59,60 2-Deoxy-c~-KDO 30:467 9-(6-Deoxy-ct-L-idopyranosyl) adenine 4:233 synthesis of 4:233 3-Deoxy-ot-L-xylo-hexopyranoside 14:182 1-(2-Deoxy-[3-arabino-hexopyranosyl) thymine 4:230 synthesis of 4:230 9-(6-Deoxy- [3-D-allopyranosyl) adenine 4:233 synthesis of 4:233 7-(2-Deoxy-13-D-arabino-hexopyranosyl) theophylline 4:233 synthesis of 4:230 3-Deoxy-p-D-furanurono-6,1-1actone 14:506 9-(6-Deoxy-[3-D-glucopyranosyl) adenine 4:233 synthesis of 4:233 2-Deoxy-[3-D-lyxo-hexopyranose 4:230 4-Deoxy-[3-D-xylo-hexop yranoside
derivative 14:164 7-( 3-Deoxy- [3-D-xylo-hexop yranos yl )theophylline 4:232 2-Deoxy-p-KDO 30:465 inhibitor of CMD-KDO synthetase 30:465 3-Deoxy-[3-L-hexofuranoside 14:182 2-Deoxy-p-Neu5Ac 30:468 approach to 30:468 4-epi-2-Deoxy-f3-Neu5Ac 30:468 approach to 30:468 6-Deoxy- p-ribohexopyranos-3-ulose 5:602
239
2-Deoxy-~3-ribo-hexopyranose 4:231 2-Deoxy-[3-ribo-pyranosyl cyanides 10:354 1-(3-Deoxy-[3-threo-pentofuranosyl) uracil 19:515 4-Deoxy-y-rhodomycinone 4:354 synthesis from mannose 4:354 synthesis of 4:352 Deoxy-~-santonin 7:212 Deposphoglycogenyl synthase 25:525 DEPC 4:92,93 cyclodimerization with 4:92,93 Dependent aldolases 30:423 synthesis of 30:423 Dephenyl thiolation 14:306 Dephosphorylation of retinoblastoma protein 25:270 Deplancheine 1:118 (+)Deplancheine 18:333Depolarisation 21:8,16,17,19,102 Depolymerisation 21:96 2-Deprenylrheediaxanthone B 30:620 from hypericum 30:620 Depressant activity 21:581 on central nervous system 21:581 Depression 30:368,627 role of hyperforin inhibitor 30:627 role of serotonin (5-HT) 30:368 Deprotection 4:282,283 of oligonucleotides 4:282,283 oftriethyl silyl group 4:533 with tetra-N-butylammonium fluoride 6:119-122 Deprotection alcohol 1:558 with TMSCIfNaI 1:558 Deprotonation 10:425 LDA-mediated 10:425 ofallylic ester 10:425 of 3-C-methyl-3-deoxy-2-ulose derivative 10:414,415 with N-lithio-2,2,6,6tetramethyl-piperidine 10:414, 415 asymmetric 11:241,242 azabicyclic ketone 11:241,242 Depsides 9:317,328
Depsipeptide antibiotics 21:408 Depsipeptides 9:213;10:250,251,256, 259,263,267,284,295-298;23:341 DER 30:800,814 antinociceptive effects of 30:800 resistance to enzymatic degradation 30:814 DER analogue 30:817 DER peptides 30:816 structural modifications of 30:816 Dercitamide 23:274;25:893,894 derivatives of 23:700 Dercitin sp. 25:893,894;28:686 antitumor activity of 28:686 antiviral activity of 28:686 immunomodulatory properties of 28:686 violet acridine alkaloid from 28:686 Dercitus 25:893 Derivatization 21:542 Dermaseptin I 23:341 Dermasterias imbricata 7:306;15:66; 25:824 2,4-di- O-methyl-[3-Dquinovopyranosyl-( 1>>2)-5O- sulphate-[3-D-fucofuranosyl from 15:66 imbricatine from 7:306 Dermatophagoides farinae 28:417
Dermatophagoides pteronyssinus 28:417-430
Dermatophilus congolensis 28:394 skin infection of cattle by 28:394 Dermatophytes 22:61 Dermocanarin I 20:277 Dermocibes sp. 22:556,579 Dermorphin 30:799,801,807,813,814 as 8 agonist 30:814 as ~t agonist 30:799 as ~t-selective agonist 30:807 inhibitory effects of 30:801 pharmacological activity of 30:813 Derris 26:487;27:844 Derris araripensis 7:177,193 Derris laxiflora 29:785
240 Derris Derris Derris Derris Derris Derris
nicou 7:177,193 scandens 27:844 sericea 7:177,193 trifoliata 7:176-178 ulignosa 7:181,182 urucu 7:177,193
Des-(25-28)-thymosin al 8:433,434 15-Desacaetylundulatone 26:816 (+)-Desacetoxymatricarin 14:357,358 Desacetoxymatricin 27:581 Na-Desacetyl- 17-O-acetyl- 18-hydroxyisoretuline 1:38,39 Na-Desacetyl- 18-hydroxyisoretuline 1:38,39 Desacetylakuammiline 5:126 N-Desacetyllappaconitine 25:528 Desacetyllaurenobiolide 27:564 N-Desacetylspermostrychine 26:1052, 1053 Desacetyltacraline 5:126 Desacetyltulipinolide- 1[3,10ot-epoxide 27:572 Desalanyl-N-acetylactinobolin 16:11 synthesis of 16:11 Desangelchrysamin 27:551 N-Desbutyl halofantrine 22:149 16R-Descarbomethoxytacamine 9:179,180 16S-Descarbomethoxytacamine 9:179,180 Descobalto-cobyrinic acid 9:598 15-Desenecioyl bruceoside-A 7:373 Desepo x y-4,5 -didehydro methylenomycin A 14:593 Desepoxymethyl enomycin A 14:602 Deserpidine 3:399,403,412-415;8:283; 9:171 ;13:631 ;19:748;21:84,488;25:8 from Rauwolfia serpentina 3:399,403,412-415 ;8:283; 9:171 ;13:631 ;19:748 synthesis of 3:412-415 Deserpindine (11-demethoxyreserpme) 25:8 Desethyleburnamonine enamine 14:729 17-oxy-20-desethyl-A2~ didehydroebur- namonine from 14:729 20'-Desethyl-20'-deoxyvinblastine 4:32;14:861
20'-Desethyl-20'-deoxyvincovaline 14:861 Desethylflavocarpine 1:137 synthesis of 1:137 Desethylibophyllidine 5:126 Desferrioxamine 22:328;26:992 Desformyl desoxypyoverdin D 9:550 Desformyl pyoverdin D 9:550 Desglucosylstevioside 15:18 from Rubus suavissimus 15:18 Desilylation 8:263 with HF-pyridine 8:263 of N-(trimethylsilyl) methyl iminium ions 1:325,328 with cesium fluoride 1:249 Desipramine 26:1063 D6sir6 and Prandi 29:455 carbafuranose synthesis by 29:455 Deslanoside 15:361,362 Desmal 25:546 Desmarestia menziesii 26:471 Desmethoxy streptonigrin 24:454 FPTase inhibition by 24:454 Desmethoxycuanzine 8:284-292 from 2-acetylbutyrolactone 8:284,285 synthesis from 8:284-292 Desmethoxytullidinol 22:574 Desmethyl quaternine 9:185,186 4-Desmethyl sterols 25:56,57 N-Desmethylacronycine 20:793 C18-Desmethylcytochalasin D 8:212217 synthesis of 8:212-217 5-Desmethylnobiletin 5:654 Desmethylvaracin 23:236 3,4-Desmethylvaracin 25:834 Desmia sp. (red alga) 5:343 Desmodium 21:525 Desmodium adscendence 21:659; 22:519 Desmodium polycarpum DC. 22:519 for convulsions 22:519 Desmodium pulchellum 22:519 for convulsions in infants 22:519 Desmodium styracifloium 25:93 Desmodium triflorum DC. 22:519 for convulsions 22:519
241 Desmopsamma anchorjkata 26:72 Desmotroposantonin 7:237 Desmutagenic activity 21:642 Des-N-methylnoracridones 13:352 Des-N-methylnoracronycine 13:370,371 synthesis of 13:370,371 Des- O-methyllasiodiplodin 9:288,289 Desorption techniques 13:652 Desosamine 5:615,616;13:155,156,159 ~-D-Desosaminyl methymycin 11:151 2-Desoxo- 15a-methyl- 14~-hydroxyMFA 28:347 discovery of 28:347 Desoxoalstonerine 13:402,403 Desoxodehydrolaserpitine 5:725,727 2-Desoxoparaherquamide A 28:331 nematocidal activity of 28:331 2-Desoxo-PHA 28:347 discovery of 28:347 Desoxy- 16-buxidienine 2:205 11-Desoxyanthracyclines 14:22 Desoxyasperdiol 10:29,30 by directed hydromagnesiation 10:29,30 synthesis of 10:29,30 Desoxybenzoin 4:382,384 robustic acid from 4:382,384 isorobustic acid from 4:382,384 11-Desoxydaunomycinone 14:23 asymmetric synthesis of 14:23 7-Desoxydaunomycinone 14:5,6 6-Desoxydaunomycinone 14:7 2-Desoxy-D-glucose 25:613 Desoxynivalenol (vomitoxin) 9:206, 207,217 218 13-Desoxyphomenone 6:552 from Hansfordia pulvinata 6:552 Desoxypicropodophyllin 18:552, 553,555,596 (+)-Desoxypodophyllotoxin 18:586, 588,59O Desoxypodophyllotoxin 5:480,481,483 Desoxyribonucleotides synthesis 26:924 18-Desoxy-Wieland-Gumlich aldehyde 1:36 Dess-Martin oxidation 19:370-371; 26:1244 Dess-Martin periodinane 19:357;23:190
Destomic acid 4:130 Destruxin-A4 chlorohydrin 25:800 Desulfonylation 19:77;11:349 Desulfurization 21:426 (+,-)-DET 6:263,269,271,278 Det2-cDNA 25:419 Detection 27:671 of sulfate groups 27:671 Dethioacetalization 12:348 Detox 28:543 for immunotherapy 28:543 Detoxification 21:4,108,161,165,177; 25:313,334,335,343 ;26:1012 of heme 25:334,335,343 of tomatine 25:313 of xenobiotics 26:1012 Detoxin 12:412 Detoxin B~ 12:412 Detoxin B3 12:412 Detraium microcarpum 21:611 Detritylation 4:276-279,282,284 Deuterated glycerol 11:422,423 asymmetric synthesis of 11:422,423 3-Deuterio-4-methylpyrocatechol 8:309 Deuteriosuccinic acid 8:72 27-Deuterocholesterol 5:774 3-Deuteroisoreserpine 25:8 Deuteromycotina 9:202 Deuteroporphyrin IX (DPIX) 25:355 Deutziol 9:455 Dexamethasone 5:713,714,602,605, 608;25:463,464 as down-regulator of TNF-a 25:465 as immunosuppressive drug 25:464 guggulsterones from 5:713,714, 602,605,608 3'-Dexoyadenosine 19:515 1-Dexoynojirimycin 10:543-546,549 antihyperglycemic activity of 10:526 antiviral activity of 10:529 by enzymatic aldol condensation 10:535,536 from Bacillus polymyxa 10:524 from Bacillus subtilis 10:524
242
from Bacillus amyloliquefaciens 10:524 from Bacillus 10:524 from Morus bombycis 10:524 from nojirimycin 10:524,525 from Omphalea diandra 10:524 from Streptomyces lavendulae 10:524 from Streptomyces lavendulae subsp, trehalostaticus 10:524 glycosidase inhibitors 10:525 intramolecular aminomercuration of 10:532 intramolecular reductive amination of 10:530 synthesis of 10:529-538 Dextran induced edema 25:46 Dextran sulphate 30:397,398 activity in quantitative syncytium formation assay 30:398 in HIV therapy 30:397 in vivo efficacy of 30:398 inhibitory effect of 30:398 on viral binding 30:398 endo-Dextranse 7:35,36 Dextransucrase 7:69 from Streptococcus sanguis 7:69 Dextrinase 10:504 Dextrins 10:463,464acatalytic hemihydrogenation 10:463 D-Glucono-nitriles 10:463,464 Nef reaction of 10:464 24-Dexyoxytrogenin 25:97 Dezoxiben 25:593 D-Gal N 25:466 hepatic intoxication with 25:466 D-Gal N/LPS 25:459-461 liver intoxication with 25:462 D-Gal N/LPS model 25:468 D-Gal N/LPS-induced liver injury 25:460,467,472-474 D-gal N/TNF-a 25:460,461 liver intoxication with 25:462 fl-l,6-D-galactopyranose 25:429 D-galactosamine (D-GaIN) 25:219,461, 463,465,468,471,473,477 ot-D-galactose 21:162,169
cx-D-galactosidase 21:160,161,168 D-GalN/LPS model 25:464 D-GalN/LPS-intoxication 25:468 D-GaiN-induced cytotoxicty 25:468 D-GaiN-induced liver injury 25:463, 469 [3-D-glucans 23:116 regular conformations of 23:116 D-Gluconolactone derivative 30:445 coupling of 30:445 [3-D-glucopyranosyl (1---~2)-[3-D-glucopyranosyl 21:732 D-Glucose 23:107 polymers of 107 D-Glucose aldehyde 30:443 role in aldol reaction 30:443 hydrogenation of 30:443 cyclization of 30:443 [3-1,2-D-glucosidase 25:306 [3-D-glucuronic acid 21:169 [3-D-glucuronidase 21:157,160,161,169 D-Glyceraldehyde derived allylic alcohols 10:436,437 Johnson-Claisen rearrangement of 10:436,437 D-glycero-D-allo/altro 30:442 diastereomeric mixture of 30:442
D-glycero-D-allo-2-nonulosonates 30:468
D-glycero-D-galacto/talo 30:442 diastereomeric mixture of 30:442 D-glycero-D-gluco/mann 30:442 diastereomeric mixture of 30:442
D-glycero-D-manno-2-nonulosonates 30:468
D-glycero-ot-D-talo-octulosonic acid 30:419 DHA 30:65,420 from carp oil 30:65 structure of 30:420 DHA-Chlorella 30:788,789,790 anti-hyperlipidemic effect of 30:788,790 DHEAsulfate (DHEAS) 24:351-398
243
Di(4,4'-hexyloxy-carbonylphenyl) ether 20:709 Diabrotica undecimpunctata 25:792 Diabrotica virgifera 26:867,868 Diacarms 25:688 2,4-Diacetamido-2,4,6-trideoxyhexopiranoses 30:434 condensation of 30:434 2,4-D iac etamido-2,4,6-trideo xyhexopiranoses 30:434 synthesis of 30:434 condensation of 30:434 Diacetone glucose 10:412 2,15-Diacetoxy- 13-hydroxy- 11 -epi APO 13:522 1(x,3[3-Diacetoxy-23,24-dinorchol-5-en22-ol 11:388-390 1c~,3~-Diacetoxy-23,24-dinorchola-5,7dien-22-al 11:398-402 synthesis of 11:398-402 3-( 2',3 '-Diacetoxy-2'-methyl-butyryl)cauhtemone 7:185 1,3-Diacetoxy-5-(2 '-acetoxy- 8 'oxotridecyl)benzene 30:132 structure of 30:132 1,3-Diacetoxy-5-pentadecylbenzene 30:128 structure of 30:128 2(x,7cx-Diacetoxy-6[3-isovaleroxylabda8,13-dien- 15-ol 17:27 1(x,2c~-Diacetoxy-6 p,9 p-difuroyloxy-4 phydroxydihydro- p-agarofuran 29:87 activity in EBV assay system 29:87 2,13-Diacetoxy-8-hydroxy- 11-epi APO 13:522 Diacetoxyavarol 15:300 1cx,3[3-Diacetoxychola-5,7-dien-24-al 11:398-402 synthesis of 11:398-402 1~x,3[3-Diacetoxychola-5,7-dien-24-ol 11:398-402 synthesis of 11:398-402 1c~,3~-Diacetoxychola-5-en-24-ol 11:388-390 5,8-Diacetoxynerolidol 27:587 Diacetoxyscirpenol 21:233
(-)- 15c~,16(x-Diacetoxyspongian 6:108, 109 Diacetyl dimethylbartogenate 7:132,133 3,13-Diacetyl GA3-7-aldehyde 8:128, 129 Diacetylajmaline 9:183,184 Diacetylenic allo-xanthin 6:150,153 C40-Diacetylenic carotenoids 6:149 3,13-Diacetyl-GA3 phenacyl ester 8:133,134 synthesis of 8:133,134 Diacetylirumamycin 5:599 ozonolysis of 5:599 N'~176 trimethylsilylethyl ester 21:394 2,4-Diacetylphloroglucinol 21:186 Diacetylsandwichine 9:183-185 Diacetylsarpagine 9:174 N,O-Diacetylsolasodine 20:490 Diacyglycerol (DAG) 25:271,483,487, 488,516,542 1,2,-Diacyl-3 a-D-glucuronospyranosylsn-glycerol taurieamide 25:873 Diacylglycerol 21:50 Diacylglycerol acyltransferase 25:797 Diacylglycerol- 1-oleolyl-2-acetyt-rac glycerol 25:488 1,3-Diacyloxypropanes 13:53,54 Diadematidae 7:283 Diadinoxanthin 23:178 Diadzein 22:458,460 Diagnostic criteria 30:372 for autistic disorder 30:372 Dialdehyde 8:18,19 18-epi-Dialdehydes 6:129 Dialkoxy anils 4:544 o~,f3-Dialkoxy ketone 11:235 2,6-Dialkoxy ketones 14:647 3,4-Dialkoxyfurans 12:19,20 Diels-Alder cycloaddition 12:19,20 with alkyl coumalates 12:19,20 Dialkyl azodicarboxylates [4+4] cycloaddition 12:424,425 to 3-[(1S)-2-exo-alkoxy- 1apocamphanecarbonyl]2-oxazolones 12:424,425 Dialkyl ethers 2:4
244
Dialkyl tartrates 14:489 2,6-Dialkyl-2-cyanopiperidines 6:431, 432 trans-2 ,5 -D ialkyl-3 ,4-de h ydrop yrro lines 6:441 synthesis of 6:441 trans-2,5-Dialkylated pyrrolidine 11:256,257 cis-c~,ot'-Dialkylated [3,[3'-heterosubstituted-oxocanes 10:214 Dialkylation 6:332,341 Dialkylboranes 9:366 cis-Dialkylpiperidine 19:34 2,6-Dialkylpiperidines 6:424-434 from 1-benzyl-2,6dicyanopiperidine 6:433 synthesis of 6:424-434 cis-2,6-Dialkylpiperidines 6:431,432 trans-2,6-Dialkylpiperidines 6:431,432 2,5-Dialkylpyrrolidine ant alkaloids 6:443 enantioselective synthesis of 6:443 2,5-Dialkylpyrrolidine s 6:437,438 by reductive amination 6:437,438 in Monomorium species 6:436 in thief ants 6:434 synthesis of 6:437,438 2,5-Dialkylresorcinol 9:322 Diallenic carotenoids 6:135,136 Diallyl cuprate 12:425,426 Diallyl disulfide (DADS) 459,469 Diallyl sulfide (DAS) 23:459,469 Diallyl thiosulfinate 23:457,459,467 Diallyl trisulfide (DATS) 341,459,469 3,5'-Diallyl-2'-hydroxy-4-methoxybiphenyl 24:861 anti-fungal activity of 24:861 (E,E)-Diallylic ether 8:196 synthesis of 8:196 Diamagnetic-y-gauche effect 9:119 5,7-Diamino-3,5,7,9-tetradeoxy-2nonulosonic acids 30:420 N-acyl and O-acetyl derivatives of 30:420 2,4-Diaminobutyric acid 9:547,548,553 2,3-Diaminoglucosyl analogs 6:406,407 meso-Diaminopimelic acid 6:404
Diaminopimelic acid-diaminopimelic acid (DAP-DAP) linkage 12:95 Diaminopimely-D-alanine 12:96 Dianchinenoside E 26:37 Dianchinenoside F 26:37 3,4:l',6'-Dianhydromaltose 10:511,512 from 2,3,2',3'-tetra- O-acetyl- 1', 6'anhydro-6-deoxy-4-O-p-tolylsulfonyl-[~-maltose 10:511 1,4:3,6-Dianhydromannitol D~-pbromobenzoate 2:164 1,6:3,4- D ianhydr o-13-D,L-allohexopyranose 14:184 Dianilinophosphoric chloride 18:397 Dianilinophosphoric esters 18:397 Dianilinophosphoryl chloride 14:286 Dianion 11:284,285 alkylation of 11:284,285 condensation of 12:9,10 from 4-[tert-butyldiphenylsilyl)oxy]-2-(tributyl-stannyl)(E)-2-buten- 1-ol 12:9,10 of FAMSO 6:323-325 stereoselective 11:284,285 with 1-TMS-2-pentyne 11:284, 285 with ot,13-epoxy cyclohexanone derivative 12:9,10 Dianion aldol condensation 12:69 Dianosides A-1 26:32 analgesic activity of 26:32 Dianthus barbatus 26:32,56 anti-inflammatory agent from 26:32 Dianthus caryophyllus 26:32,594; 29:593 Dianthus chinensis 26:3,32-34 Dianthus delloides 26:32 Dianthus sp. 5:659 acylated anthocyanins 5:659 malic acid in 5:659 Dianthus superbus var. longicalycinus 26.'56 anti-bleeding activity of 26:56 anti-tumor activity of 26:56 Diaperoecia californica 17:90,92 Diaphoretic agent 23:642 of Teucrium sp. 23:642
245 Diapo-carotenoids 7:317;20:602; 30:517,528 Diaporte helianthi 15:345 Diarrhetic shellfish poisoning (DSP) 28:653 yessotoxin in 28:653 Diarrhetic shellfish poisons 21:301 Diarrhoea 30:394,406,691 Celastrus gaumeri in treatment of 30:691 2,6-Diaryl-3,7-dioxa bicyclo [3.3.0.] octanes 24:740,755-762 Diarylalkanoids 27:852 Diarylbutanes 17:349 Diarylcyclobutanes 17:348 Diarylethanoid derivatives 30:222 moracins as 30:222 norlignans as 30:222 Diarylether 17:388 Diarylheptanoids 20:276;23:802,805; 25:543;27:852 activity of 17:375;27:852 1,7-Diarylheptanoids 26:881 Diarylpyrazoles 30:196,197,198 structure of 30:197 Dias synthesis 30:44-46 of (-)-pironetin 30:44-46 Diasesartemin 7:219 Diastereoconversion 12:479 Diastereodifferentiating isomerization 14:510 4-hydroxy-2-cyclopentenone acetal from 14:510 of meso-3,4-epoxycyclopentanone 14:510 Diastereofacial selection 13:62-70 Diastereofacial selectivity 4:172,173 of chiral epoxidizing agent 4:172,173 Diastereolselective alkylations 1:613-616 Diastereolselective cyclopropanations 1:629-632 of c~,[3-unsaturated acetals 1:629-632 Diastereomeric products 30:547 Diastereomeric resolution 1:585-588 Diastereomers 13:280-282;22:227, 231;27:363,364
Diastereoselection 10:215 1,2-Diastereoselection 4:443,448,451, 472,474 Diastereoselective 4:328,329;12:15,16 Diastereoselective addition 14:508,509 of chiral aryl Grignard reagents 14:508,509 to carbonyl compounds 14:508, 509 of Grignard reagents 1:621 to ketals 1:621 Dlastereoselective aldol reaction 30:431 ofpyruvate 30:431 Diastereoselective alkylation 17:324 Diastereoselective cyanation 14:473 Diastereoselective cyclizations 1:590,591 Diastereoselective cyclopropanation 6:544,545 Diastereoselective eliminative cleavages 1:618,619 Diastereoselective halolactonization 1:620,627-629 Diastereoselective Michael addition 6:86,87,286 Diastereoselective reduction 1:595 Johnson-Yamamoto rationale 1:595 ofcarbonyls 1:622 Diastereoselective routes 29:471 to carbaaldopyranoses synthesis 29:471 Diastereoselective synthesis 12:479-481; 27:208 of(3R,4R)-staine 12:479-481 of 2(c~-hydroxyalkyl) piperidines 12:453 of 4c~-aryldecahydroisoquinolines 12:456-463 of 6-hydroxy-4ct-phenyldecahydro 12:457 of B/C-trans-morphinan 12:464-471 of Blepharin 27:188,208,209 of octahydroisoquinolines 12:457 ofpiperidine derivatives 12:471 ofpyrrolidine derivatives 12:471
246
of methylphosphonate 13:276-278 of phosphorothioate 13:276 Diastereoselectivity 11:359;16:372 Diastereotopic groups 17:481 Diastrovaricin 23:54 Diastrovaricins I 23:67 Diastrovaricins II 23:67 Diatoms 21:300,302 Diatoxanthin 20:579,580;23:179 Diatretyne nitrile 21:190 Diatriba 25:186 1,4-Diazabicyclo [2,2,2]-octane 27:850 1,5-Diazabicyclo [4.3.0] non-5-ene 11:353 Diazabicyclo [5,4.0] undecene 12:466 1,8-Diazabicyclo [5.3.0] undec-7-ene 11:341,342 3,8-Diazabicyclo[3,2,1] octane 10:135137 synthesis of 10:135-137 Diazabicyclo[5.4.0]undec-7-ene (DBU) 424,425 Diazene 3:20;22:196,197,200,204, 213,214,219,220,233 Diazepam binding inhibitor 27:803 Diazidation 10:465 ~x-Diazo [3-keto ester acetal 14:509 2-Diazo-3-oxopentanoic acid derivatives 12:172 with 4-acetoxy [3-1actam 12:172 3,8-Diazobicyclo [3,2,1] octane 10:107,117 Diazoketone 1:492 cyclization of 1:492 from adenosine 10:593-595 preparation of 10:593-595 Wolff rearrangement of 10:593-595 a-Diazoketone 19:18 Diazoketone insertion 1:555,556,564 copper mediated 1:555,556,564 cyclization 1:492 Diazomethane 1:404,405,439 esterification of 1:404,405 methylation with 1:435 ring expansion with 3:12
sugar aglycone linkage cleavage by 7:155,156 Diazosulfone 22:331 Diazotization 3:325,226 Diazotized aniline 19:89 DIBAH reduction 6:428;14:634;19:172 DIBAL 1:177;14:529,530;19:318 reduction with 6:285,286,288, 293,294,299,549,550;11:432, 457;13:456,464,465;20:67 DIBAL reduction 21:391 Dibalanocarpol 23:533;26:556,562 (DIBAL-H) reduction 10:428,429 of ot,[3-unsaturated ester 10:428,429 Dibenz [b,d] oxocin derivative 15:34,35 Dibenz [b,g] azecine derivative 6:492, 493 Dibenz [c,g] azacycloundecine 6:496 Dibenz [c,g] azonine derivartive 6:474, 475 Dibenz [d,f] azonine derivatives 6:477, 478,480 from benzylisoquinoline derivatives 6:477,478,480 from 1-halogenobenzylisoquinoline 6:482 from neoproaporphine intermediates 6:480 from neospirene intermediates 6:480 synthesis of 6:477,478,480,482 Dibenz[b,f] azecine derivative 6:492,493 Dibenzazecine 6:487-493 Dibenzindolizidine 3:425 Dibenzlbutyrolactone enerolactone 26:186 Dibenzo [d,f] azonines 3:468,469 Dibenzo oxazacycloundecine derivatives 6:494 Dibenzoate 10:597 from cis-2-buten-l,4-diol 10:597 from D-glucose 10:597 Dibenzocyclooctadiene 24:775-781 derivatives of 24:775-781 synthesis of 24:775-781 Dibenzocyclooctadiene lactone lignans 29:360
247 araliangin as 29:360 10-demethoxystegane as 29:360 episteganangin as 29:360 (-)-9-episteganol as 29:361 neoisostegane as 29:360 steganolides as 29:360 X-ray structure of 29:361 Dibenzocyclooctadiene lignans 26:196, 197 Dibenzocyclooctadienes 17:346 Dibenzocyclooctanes 20:276 Dibenzopyrrocoline alkaloids 6:482 Dibenzoquinolizine 6:492,493 hexahydrodibenz [d,g] azecines from 6:492,493 Dibenzoyl-p-D-ribopyranose 10:589,590 condensation of 10:589,590 N, N-Dibenzyl benzoyl acetamides 14:650,651 photolysis of 14:650,651 (4S,5R)-3,5-Dibenzyl-4-isobutenyloxazolidin-2-one 12:480 Dibenzylazodicarboxylate (DBAD) 12:157 Dibenzylbutane enterodiol 26:186 Dibenzylbutane lignans 26:191 Dibenzylbutane nordihydroguairetic acid 26:187 2,3-Dibenzylbutane- 1,4-diol 26:191, 234,249,250 inhibition of Ca2+ influx 26:234 Dibenzylbutanes 17:315 Dibenzylbutyrolactone 30:570 Dibenzylbutyrolactone yatein 29:369, 371,380 steganes synthesis from 29:369, 371,380 Dibenzylbutyrolactones 5:485-490,320; 30:587 Dibenzylbutyrolactone-type lignan 30:587 tris-Dibenzylideneacetone dipalladium 8:277,278 (-)-(2S,3S)- 1,4-Dibenzyloxy-2,3butanediol 14:490 unsaturated acetal from 14:490 Dibenzyltrisulfide 28:403 as oviposition inhibitor 28:403
(2S,6R,8R,9R) 2,8-Diboromo-[3chamigrene 6:62,63 from (8R,9R)-8-bromo-9hydroxcy-(E)-y-bisabolene 6:62,63 synthesis of 6:62,63 Dibroinoageliferin 25:779,780 Dibromide synthesis 29:482,483 as fucosidase inhibitors 29:482 by Rassu 29:482,483 2,6-Dibromo-3-methylbenzoquinone 21:434 endo-3 ,9-Dibromo-4-bromomethyl camphor 4:629 reactivity towards bromination 4:629 7-syn-9-Dibromo-6-endomethylisofenchone synthesis 4:629 (-)-(2R, 6S, 8S,9S)-2,8-D ibromo-9hydroxy-c~-chamigrene 6:62,63 by asymmetric carbocyclization 6:62,63 from (E)-~-bisabolene-8(R),9(S) epoxide 6:62,63 from Laurencia nipponica 6:63 synthesis of 6:62,63 (+)-3,9-Dibromocamphor 16:138 (+)-9,10-Dibromocamphor 16:138 (+)-3,3-Dibromocamphor 4:628,629, 638,639;16:144 (+)- 10-bromocamphor from 4:638,639 (+)-endo-3 ,9-Dibromocamphor 4:634,635,643 acid catalysed rearrangement 4:635,643 reactivity towards bromination 4:629,630 (+)-9,10-Dibromocamphor 4:657,658 C(3)-methylation of 4:657,658 Dibromophakellstatin 25:770 2,6-Dibromophenol 17:81 2',4'-Dibromophenoxy ether 21:284 4,5-Dibromopyrole-2-carboxylic acid 26:819 methyl-ester of 26:819 Dibromosceptrin 21:73;25:779 3,5-Dibromotyrosine 21:307
248
Dibromo-tyrosine derivatives 25:719 Dibromotyrosine-derived metabolites 25:719 Dibromoverongiaquinol 21:307 4,5-Dibrompyrrole-2-carbamide 25:784 Dibutyl cAMP 25:271,488,509 Dibutyltin oxide 1:274 for stannoxane preparation 1:274 1,2-Dibutyroyl inositol 18:409 4,5-Dicaffeoyl quinic acid 23:764 Dicaffeoyl tartaric acid 25:663,667,932 Di-caffeoylquinic acid 23:753 1,5-Di-caffeoylquinic acid 23:753 1,4-Di-caffeoylquinic acid 23:753 3,4-Di-caffeoylquinic acid 23:753 3,5-Di-caffeoylquinic acid 23:753 Dicaffeoylquinic derivatives 23:745 Di-C-alkylation 10:413 of D-mannose derivative 10:413 5,7-Dicarbanion 21:746 [3-Dicarbonyl 10:343-348 Dicarbonyl coupling 3:99 by Mukaiyama procedure 3:99 intramolecular 11:345,364-467 with TiC13/LAH 3:80,81 with TiCI3/Zn-Cu 3:80,81 ot-Dicarbonyls 8:262 synthesis of 8:262 Dicentra spectabilis 27:163 Dicentrine 21:73;22:20 Dicerocaryum zanguebricum 26:1158 6,8-Di-C-glucosyldiosmetin 23:747 Dichamanetin 9:399,400 1,3-Dichloro- 1,1,3,3-tetraisopropyldisiloxane 18:409 2,3-Dichloro-4,5-dicyanobenzoquinone (DDQ) 11:156,165 2,3-Dichloro-5,6-dicyano- 1,4-benzoquinone 21:735 Dichlorobis (acetonitrile) palladium (II) 21:381 Dichlorocarbene addition 10:413 Dichloroimine 21:346 2,6-Dichloroisonicotineic acid 26:946 Dichloroketene 13:6 [2+2]cycloaddition with 13:6 Dichlorolissoclimide 25:269,769 (Dichloromethyl) boronic ester 11:409, 410
synthesis of 11:409,410 (Dichloromethyl) lithium 11:410 Dichloromethylenation 3:223 Dichloromethylphosphine 13:276 9,10-Dichloro-N-methyldysideathiazole 25:890 2,6-Dichlorophenol 25:765 2,4-Dichlorophenol 25:767 2,4-Dichlorophenoxy acetic acid 7:90, 97,111;26:306 Dichomine 5:126,183 Dichomine-type alkaloids 5:106 Dichroa febrifuga 20:522;22:146 Dichrostachys cinerea L. 22:519 for epilepsy 22:519 Diclofop 26:374 6,6-Di-C-methyl heptopyranose derivative 10:414 3,3-Di-C-methyl-2-ulose 10:415 2,2-Di-C-methyl-3-deoxy-4-ulose 10:414,415 2,2-Di-C-methyl-3-ulose 10:415 4,4-Di-C-methyl-4-deoxy-D-glycerohexo-pyranoside-2-ulose 10:414,415 Dicoumarol (coumarin) 27:847;29:584 effects as anticoagulant 29:584 Dicraeopetalum stipulare 27:271 Dicranostigma ' .'mchetianum 27:162 Dicranostigma tactucoides 27:155,162 Dicranostigma leptopodum 27:162 Dicrotalic acid 21:730,732;22:169 Dicrotaline 1:271 Dicrotonic acid 7:143,144 Dictamine 3:385,386 Dictamnus albus L. 22:519 for hysteria 22:519 Dictindiol 9:79,80,87 Dictinol 9:79,87 Dictintriol 9:79,80,87 Dictydiaethalium plumbeum 12:366,370 arcyriaflavin-D from 12:366,370 Dictyoceratida 6:107,111;19:568 Dictyoceratidaquinone 15:300 Dictyoceratin-A 5:432,433,292,293 Dictyochromenol 15:294 Dictyodendrilla cavernosa 18:718 Dictyodendrilla sp. 28:691 Dictyodial 5:370
249 (-)-Dictyolene 6:27 by Collins allylic oxidation 6:27 from Dictyota acutiloba 6:27 from 6-epi-c~-santonin 6:27 synthesis of 6:27 Dictyoloma incanescens 26:820 Dictyoloma peruviana 26:820 Dictyoloma vandellianum 26:820 Dictyolomide 26:821 Dictyols 17:97 Dictyoptera 22:371 Dictyopteria genus 25:841 Dictyopteris divaricata 6:16,18 dictyopterone from 6:16 [3-dictyopterol from 6:16,18 (-)-zonarene from 6:15 Dictyopteris undulata 6:17 isozonarol from 6:17 zonarol from 6:17 Dictyopteris zonaroides 6:15 (-)-zonarene from 6:15 13-Dictyopterol 6:18,19 by Peterson olefination 6:18,19 by van de Walle approach 6:16 from Dictyopteris divaricata 6:16,18 synthesis of 6:16,18,19 13-Dictyopterol precursor 6:16 from c~-phenylselenide 6:16 synthesis of 6:16 Dictyopterone 6:16 by van de Walle approach 6:16 from Dictyopteris divaricata 6:16 synthesis of 6:16 Dictyostatin 19:557 Dictyostelium 9:220 Dictyostelium discoideum 5:275,384; 25:523;26:80 Dictyosterol 30:505,507 13C NMR spectra of 30:505 IH NMR spectra of 30:505 synthesis of 30:507 Dictyota 9:78,79,86 Dictyota acutiloba 6:27 (-)-dictyolene from 6:27 Dictyota crenulata 5:370,70;6:70 Dictyota dichotoma 9:86,88
Dictyota divaricata 6:52 Dictyota indicia 9:78-81 Dictyota linearis 6:52 (+)-amijitienol from 6:52 dolasta- 1 (15)-7,9-trien- 14-ol from 6:52 isoamijiol from 6:53 Dictyota spinulosa 5:370 Dictyotaceae 6:52 dolastanes from 6:52 marine diterpenes from 6:52 Dictyotene 21:305 Dicyclic-O-glucoside 22:427 1,2-Dicyclohexyl-l,2-ethanediol 11:423 (S,S)- 1,2-Dicyclohexyl- 1,2-ethanediol dichloromethylboronate 11:423,424 from chiral 1,2-diphenyl ethanediol 11:423,424 (m-methyl crotyl) boronic ester from 11:423,424 Dicyclohexylborane 4:116,117 Dicyclohexylcarbodiimide 12:328 N,N-Di-cyclohexylcarbodiimide (DCC) 8:76 Dicyclohexylideethane 4:521 synthesis of 4:521 1,2:4,5-Dicyclohexylidene-myo-i nosito 1 18:401 Dicyclohexylidene-myo-inositol 18:403 Didanosine 24:474,486,488 as anti-viral agent 24:474,486, 488 Dideacetoxy argutin 9:66 7,8-Didehydro acetylenic analogue 30:521 E-2,3-Didehydroaspartic acid 15:347 1,2-Didehydroaspidospermidine 26:1050 E-2,3-Didehydroisoleucine 15:347 7,8-Didehydroisorenieratene 6:155,156 15,15-Didehydromimulaxanthin 20:580 3,4-Didehydroproline 15:347 3,4-Didehydrovaline 15:347 11,11 '-Didehydroxy-7,7-dihydroxytaxodione 20:680 from Salvia montbretii 20:680 Didemenin 13 21:252 Didemenins 21:321
250 Didemethoxycarbonyltetrahydrosecamine 5:141 Dideminine B 12:455 from Trididemnum species 12:455 Didemnakelal 25:874 Didemnenones A,B 10:244,245 Didemnid tunicate 23:234 Didenmidae 10:250 Didemnimide A 23:258 Didemnimides B 25:802 Didemnin 12:412;25:684,714 Didemnin X 10:250-257 Didemnin A 4:84,102-106,421, 422-258,262,263,266-272,276,277, 281,285,291 ;10:251-256,258-262, 265,266,268-272,275,276,281,285, 291 Didenmin B 5:421;25:713,757,816 antitumor activity of 5:421 antiviral activity of 5:421 immunosuppressive activity of 5:421 Didemnin C 4:103-106,276,281, 285,291 ;5:421 ;10:251,254,271, 272,281,285,291,292 Didemnin D 5:422 Didemnin E 5:422,250-257,299 Didemnin F 5:426-428 Didemnin G 5:427 Didemnin group 4:83 Didemnin Y 10:250-257 Didenmin-B (isodidemnin-I) 10:251-258,262,263,266272,276,277,281,285,291 Didemnins 5:421,254-257 antitumor activity of 5:421, 254-257 antiviral activity of 5:421,253, 254 biological properties of 10:241-302 cytotoxic activity of 5:421 immunosuppressive activity of 10:257,258 Didemnolin A 25:818 Didemnolin C 25:818,863 Didemnolin D 25:818,863 Didemnolines 25:757,816
Didemnum 25:878 Didemnum candidum 23:257,259 Didemnum chartaceum 23:248;28:631 lamellarin G 8-sulfate from 28:631 lamellarin sulfates from 28:631 lamellarin B from 28:631 lamellarin C from 28:631 lamellarin L. from 28:631 Didemnum chartcium 17:22 Didemnum conchylatum 23:258;25:802 Didemnum molle 25:883;28:630 comoramide A from 28:630 comoramide B from 28:630 cyclodidemnamide from 28:630 mayotamide A from 28:630 mayotamide B from 28:630 mollamide from 28:630 Didemnum rodriguesi 25:813, 897;28:632 caledonin from 28:632 Didemnum sp. 10:24;25:765,818,874; 28:631,634 anti-human immunodeficiency virus (anti-HIV) activity of 28:631 didemnaketal C from 28:631 didemnoline A from 28:634 didenmoline D from 28:634 polysaccharide from 28:631 Didemnum ternataum 23:234 Didemnum voeltzkowi 10:244;25:713 Dideoxy C-glycoside 10:389 2,3-Dideoxy ulosonic acids 30:465 as precursors 30:465 importance of 30:465 1,4-Dideoxy- 1,4-imino-L-allitol 7:41-43 N-benzylation of 7:41-43 N-methylation of 7:41-43 1,5-Dideoxy- 1,5-imino-D-glucitol 12:332 from D-glucose 12:332 synthesis of 12:332 1,5-Dideoxy- 1,5-imino-L- fuc itol 7:41,42 2,2-Dideoxy-2,3'-diphthalimido-13,[3trehalose 6:400
251 4,5-Dideoxy-4-phoshinyl-Llyxofuranoses 6:362,363 2,4-Dideoxy-4-phosphinyl-D-erythropento-furanoses 6:361,362 2,4-Dideoxy-4-phosphinyl-L-threopento-furanoses 6:361,362 4,5-Dideoxy-4-phosphinyul-Dribofuranoses 6:362,6:363 5,6-Dideoxy-5-(phenylphosphinyl)-Lidopyranoses 6:372 4,20-Dideoxy-5-hydroxyphorbol derivative 2:267 5,6-Dideoxy-5-phosphinyl-Didopyranoses 6:372 2,3-Dideoxyascorbic acid 4:715-718 7,11-Dideoxydaunomycinone 1:503,504 7,9-Dideoxydaunomycinone 1:505 9-(2,3 D ideo xy-D-erythrohexopyranosyl)-adenine 4:2355,6-Dideoxy-D-glucopyranoses 6:366,367 5,6-Dideoxy-D-idopyranoses 6:366,367 3,13-Dideoxy-evoninol 18:746 Dideoxyforskolin 25:269 1,2-Dideoxy-galactose 7:65 2,3-Dideoxy-hex-2-enopyranoside 10:418 (S,S)-3,4-Dideoxyhexitol 11:251-259 Dideoxyhexoses 11:214,215 by TDP glucose oxidoreductase 11:214,215 from glucose 11:214,215 in Streptomyces violaceoruber 11:214 7,9-3',4'-Dideoxykanamycin B 14:145 2,3-Dideoxy-maytol 18:745 3,4-Dideoxy-maytol 18:745 1,6-Dideoxynoj irimycin derivatives 7:42 Dideoxynucleosides 4:234 4,6-Dideoxynucleosides 4:234 2,3-Dideoxypyranosyl-purines 4:235 4,6-Dideoxy-sucrose 7:42 4,4'-Dideoxy-trehalose derivative 14:165 from 4,4'-diiodide 14:165 from trehalose 14:165
10-(2,6-Dideoxy-13-arabinohexopyranosyl) cytosine 4:234 (-)-(9R)-7,11-Didesoxy- 13deoxodaunomycinone 14:8 10,12-Dideuterated reserpine 25:10 Didicus flavus 23:165 Didrovaltrate 16:295 from Valeriana wallichii D.C. 16:295 synthesis of 16:296-297 Didymium bahiense var. bahiense 29:252 constituents of 29:252 fruit bodies of 29:252 Didymium iridis 29:248 Didymium minus 29:250 clerosterol from 29:251 clionasterol from 29:251 constituents of 29:250 22,23-dihydrobrassicasterol from 29:251 glycoside glucoclionasterol from 29:251 isofucosterol from 29:251 24-methylenecholesterol from 29:251 poliferasterol from 29:251 Didymium squamulosum 29:247 Dieckmann condensation 3:191,289, 338,339;8:192,284,293 of ethyl 2-[ 1-(2-ethoxycarbonylmethyl) piperidinyl]-proponoate 12:284 of ethyl 4-[ 1-(2-ethoxycarbonyl pyrrolidinyl)]butyrate 12:293 Dieckmann cyclization 1:183,340; 10:328,408,410,411;12:126,147, 279,308,445;13:25,26,117,131 - 133; 14:34,35 ;24:3,33-35,42,43 Diels-Alder dimerization 2:122,128 endo Diels-Alder adduct 6:33,34 in (+)-precapnelladiene synthesis 6:33,34 Diels-Alder adduct 4:388,389;6:84,85, 125,340,451 Diels-Alder chemistry 16:9 ofbicyclic intermediate 16:9 Diels-Alder cyclisation strategy 30:220 Diels-Alder equivalents 3:4
252 reaction 8:150; 26:111,138 Diels-Alder reactions 20:769,770; 21:211,434;24:8-10,27-31,195196,762,763,766,768;26:172;30:661 asymmetric 12:26,27;24:768 asymmetric intramolecular 14:502,503 atomic orbital coefficients in 4:585,586 betaenone B by 4:601,602 cadinane by 4:584,585 (+)-capnellene by 4:588 cholesterol by 4:587 (+)-coriolin by 4:588 coronafacic acid 4:590,591, 596,597 cycloaddition 16:7,219,245,422 diastereoelectivity of 4:441 dienes in 4:581-584 dienophiles in 4:584 diplodiatoxin by 4:500-602 effect of Lewis acids 4:586 Eu (fod)3-mediated 4:121,122, 143 exo versus endo transition state 1:373-374 facial selectivity in 10:351 for bicyclic compounds 8:410 frenolicin by 4:591,592,594,609 gephyrotoxin 223AB by 4:606 hetero 1:478 heterodienes in 4:583 heterodienophiles 4:112,583 high pressure 4:112,121,122 (+)-hirsutene by 4:588 imino 1:288,289;4:604,605 iminodienophile in 4:604,605 in (q-)-A 9(12) capnellene synthesis 6:46 in (+)-12-deoxy-scalaradial 6:58 in anthracyclinone synthesis 1:502,503 in synthesis of quinolines 3:387397 intermolecular 12:19,20,380; retro-Diels-Alder
10:409;12:19,20,380;16:4,24
456 intramolecular 1:71,347,478,
479;3:79,80;8:403-406;10:51, 52,155,156;11:11,92,93,99-108; 12:253;13:108,117-141,144, 149;14:735;19:11,464 intramolecular imino 1:385-382 intramolecular nitroso 1:379381,383 inverse electron demand 3:311; 16:433 Lewis-acid catalyzed 8:141; 12:26,27 non-catalyzed reaction 8:142 odd carbon equivalent 3:419 of 1,3-butadiene 19:68 of 3,4-dialkoxyfurans amides 12:19,20 of amine 16:474 of butadiene 11:340,341 of chiral 1;3-dieneacylnitroso 19:11 of chiral o-quinodimethanes 14:502,503 of daunosamine derivative 10:375 of dimethyl acetylenedicarboxylate 12:379,380 of enal 19:66 of enantiomeric tetraenic acid derivative 10:409 ofenedione 16:28,34 of furan 19:366 offuran dienes 12:253 of imines 3:55 of isoprene 19:226 of levoglucosenone 14:270,271 of methyl-(E)-3-acetoxyacrylate 11:306,307 of N-carbomethoxy pyrrole 19:77 of N-furfuryl-~-chloroacryl amides 12:19,20 of N-substituted pyrroles 19:77, 226 of optically active nitroolefin 19:144 of orthoquinodimethane 11:92, 93 of perezone 5:768 of pyranose diene 10:351
253
ofpyridyl dienophile 19:75 of styrene 16:555 precursor of 16:5,261 regioselectivity 12:16,17 retro-Diels-Alder reaction 14:821,822 stereoselectivity 12:16,17 stereospecific 19:6 transition state of 16:5 with (E)-crotonic acid 11:340, 341 with 2-azaallyl anions 1:347 with acetal 14:502,503 with bis (nitrophenyl) butadiene 12:379,380 with butadiene 11:356,357 with Danishefsky diene 16:10; 19:144, 208 with doubly activated butadienes 3:465 with isoprene 11:306,307 with ketoester 19:226 with methyl vinyl ketone 19:208 with nitroso compounds 1:359392;12:16,17,250,253,416 with ~-quinonediimide 3:322323 Diemenensin A 17:24 antibacterial activity of 17:24 Diemenensin B 17:24 (Z,E)-Dienamide 21:436 (2E,4E)-Dienamides 21:374 Dienamides 21:378 E-Diene 16:4 Diene chromophore 11:369 Diene dimerization 3:107 Ni(O)-catalysed 3:107 (Z,E)-Diene ester 12:46,47 Diene isomerization 1:447,448 7,9(11)-Diene seychellogenin 15:91 Diene synthesis 6:308 Diene-carbenoid addition 3:49 [3-Dienes 3:38,39 synthesis of 3:38,39 Dienes 4:525 formation by reductive elimination 4:525
1,3-Dienes 8:278,280 cyclization of 8:278,280 palladium catalyzed 8:280 ~-Dienes 3:38,39 cyclopenthesis from 3:38,39 Dienic acid 3:38,39,41 synthesis of 3:38,39,41 Dienic macrolides 8:240 Z,Z-1,4Dienol disilyl ethers 12:172 Lewis acid cataylzed 12:172 with 4-acetoxy-[3-1actam 12:172 Dienone-phenol rearrangement 2:253, 615,625,628;19:406 Dienophiles 12:17 from L-ascorbic acid derivatives 12:17 synthesis of 12:17 in Diels-Alder reactions 4:583 3-Dienoyl tetramic acid 14:109 Dienoylpyrrol-2(5H)-one 13:120-123 c~,[3~,,6-Dienoyltetramic acids 14:104 8,13-Di-epi-sclareol 25:252 Di-epi-7-con-O-methylnogarol 14:75, 76,78 3,8-Diepialexine 7:14 3,24-Diepibrassinolide 18:530 3,24- Diepibrassinolide- 3[3-laurate 18:533 3,24- Diepibrassinolide- 3 [3-myri state 18:533 3,24-Diepibrassinolide-3[3-palmitate 18:533 (+)- 1,8c~-Di-epi-castanospermine 12:335,336,345 synthesis of 12:335,336,345 (+)-6,7-Di-epi-castanospermine 12:337,338,345 synthesis of 12:337,338,345 (-)- 1,6-Di-epi-castanospermine 12:342344 synthesis of 12:342-344 1,6-Di-epicastanospermine 7:12 from L-gulonolactone 7:12 synthesis of 7:12 3,24-Diepicastasteron 18:496,530 2,3-Di-epi-mannostatin A 19:356 8,13-Di-epi-manoyl oxide 20:691
254 (-)-l-8a Di-epi-slaframine 12:312synthesis of 12:312 (-)-8,8a Di-epi-swainsonine 12:331,332 inhibitory activity of 12:331,332 (-)-1,8- Di-epi-swainsonine 12:325 from (S)-glutamic acid 12:325 from methyl 3-acetamido-2-Oac etyl-3- de oxy-4,6- di- O- me syl(x-D-glucopyranoside 12:326,327 (+)-2,8-Di-epi-swainsonine 12:325 (-)-2,8a-Di-epi-swainsonine 12:325,331 (-)-8,8a-Di-epi-swainsonine 12:331,332 divergent synthesis of 12:330 from 2,3-O-isopropylidene-Lerythrose 12:330,331 inhibitory activity of 12:331,332 synthesis of 12:329-332 Diepomuricanin A 18:212,219 (R,R)-Diepoxide building block 11:251,252 (S,S)-Diepoxide building block 11:251,252 7c~,8 c~,13[3,14[3-Diepoxyabietan- 18-oic acid 29:99 activity in EBV assay system 29:99 1613,23,16c~,24-Diepoxycycloartane compounds 27:472 2,3-Diepoxy-D-arabino-hept-2-enono1,4-1actone 11:457 trans-3,3-Diethofencarb 22:462 Diethoxy- 1,2-cyclobutane dicarboxylate 10:613,614 Diethoxyphosphono acetate 9:525 Diethyl (L)-tartarate 14:508 chiral ortho esters from 14:508 (+)-monomorine I from 6:44 Diethyl [2-2H2, 2-13C] succinate 11:196 Diethyl 2,2'-bi- 1-benzoate 11:125 Diethyl aluminum 2,2,6,6-tetramethyl piperidine 10:48 Diethyl amino (di-t-butoxy) phosphine 14:305 Diethyl phosphorocyanidate (DEPC) 4:83
Diethyl phthalate 11:124 9-oxo-3-fluorenelacetate from 11:124 (R,R)-Diethyl tartarate 11:346 Diethyl-3-oxo-glutarate 6:445 condensation of 6:445 with 4-aminooctanal diethyl acetal 6:45 wit ethanol 6:445 Diethylaluminum cyanide 3:213 Diethylamine 22:220 2'-Diethylamino rifamycin P 23:95 Diethyldithiocarbamate 26:1271 Diethylnitrosamine 12:399 Diethylstilbesterol 22:627 (+)-Diethyltartarate 6:264,268 L-(+)-Diethyltartrate 11:99,132,139 Dietyosphaeriafarulosa 25:898 DIF assay system 29:87 3 [3-acetoxy-8 [3-isobutyrylo xyreynosin activity in 29:87 rac- 1,2-Di-fattyacyi-3-mercaptoglycerol 18:841 5,5'-Diferulic acid 27:759 5,8'-Diferulic acid 27:759 8-O-4'-Diferulic acid 27:759 Diferuloylmethane 27:852 DiffQuick reagent 30:596 Differentiation 30:496 of human HL-60 leukemia cells 30:496 Difficidin 5:606,607 Difforlemenine 9:181 8',8'-Difluoro-abscisic acid 27:347 10,10-Difluoroarachidonic acid 9:551 2,4-Difluoroestradiol 5:451-453 Digalactosyl 1-thio analog 8:317 of ~,[3-trehalose 8:317 synthesis of 8:317 Digeminine A 12:477 from Tridedemnum species 12:477 Digenea simplex 25:846;26:478 Digestive organs motility accelerator 24:900 gingerol as 24:900 Diginatigenin 15:362 Diginatin 15:362 Digioxigenin-3-O-tridigitoxide 25:535
255
Digitalis 2:402,439;21:488;26:174 Digitalis glycosides 22:58 Digitalis lanata 15:367,375,377;25:535 Digitalis purpurea 14:439;25:535; 27:837 steroidal lactones from 14:439 digitoxin from 5:505;5:505 p-Digitatum 25:148,149 Digitolutein 26:806 Digitonin 2:54;25:308 Digitoxigenin 14:443-444,362 Digitoxin 5:505,439,362;21:488; 24:215,258-261 Diglucoside 25:200 Diglucuronate 15:26 Diglycosides 7:272,281,298 Digoxigenin 15:362 Digoxin 15:362;21:488 Digoxin-protein conjugates 15:366-368 Digydrosecurinine 21:69 0~,e0'-Dihalides 4:560-563 1,0~-Dihaloalkanes 6:313,314 ketones from 6:313,314 ct-Dihalomethylcycloheptanones 8:35 Dihalomethylithiation insertion 26:1221 matteson method for 26:1221 2,3-Dihdydroaromaticin 29:90 activity in NFkB assay system 29:90 (S)-(-)-9,10-Dihdyroxygeranylacetone 25:168 Diheptoses 4:196,206 in A eromonas hydrophila 4:196 in Neisseria meningitides 4:196,206 in oligosaccharide synthesis 4:204,205 24,24-Dihomo- 1c~,25-dihydroxy vitamin D3 11:385,386 pharmacological activity of 11:385,386 24,24-Dihomo-24-methylcholesta- 5,7diene-let,3[3, 25-triol 11:387,388 24,24-Dihomo-25-hydroxycholesterol 11:386 Dihydric phenolic lipids, cardol (1,3dihydroxy) type 30:121-137
occurrence of 30:121-122 structures of 30:123-137 Dihydric phenolic lipids, urushiol (1,2dihydroxy) type 117-118 occurrence of 30:117-118 structures of 30:117-118 Dihydro (A22,23) avermectin B l~ (ivermectin) 1:435 Dihydro alpha-agarofuran 25:171 Dihydro-~-agarofuran 23:663 basic skeleton of 23:663 14,15-Dihydro- 12-methoxyvincamine 5:126 20,21-Dihydro- 19-desoxomacroline 13:403,404 19,20-Dihydro- 19-hydroxycondylocarpine 1:40 1,2-Dihydro- 1-arylnaphthalene lignans 17:338 22,23-Dihydro- 1oc,25-dihydroxyvitamin D2 11:395-398 24R-epimer of 11:395-398 synthesis of 11:395-398 2,3-Dihydro-2,5-dihydroxy-6-methyl4H-pyra-4-one 21:674 2' o~-3' ct-Dihydro-2' cz,3 ' o~-epoxy-ABA 27:331 7,8-D ihydro-22 [3-hydroxytingenone 30:674 ~H-~H-COSY experiment of 30:674 ~H-NMR spectrum of 30:674 HMBC of 30:674 HMQC of 30:674 structure of 30:674 2,3-Dihydro-3(1-aziridinyl) withaferin A 20:245 6,7-Dihydro-3-[(3-guauiazulenyl) methylene]-8( 3H)-guaiazule ne 14:344 4,10-Dihydro-3H-naphtho [2,3-c] pyran10-one(yellow pigment) 11:127-129 (+)-nanaomycin from 11:127 synthesis of 11:129 (2R,3R)-2,3-Dihydro-5,7,3',4'tetrahydroxy-6-methoxy-3-Oacetylflavonol 15:32
256 (2R, 3R)-2,3-Dihydro-5,7,3',4'-tetrahydroxy-6-methoxy flavonol 27:17,35 structure of 27:35 (2R, 3R)-2,3-Dihydro-5,7,3',4'-tetrahydroxy-6-methoxy-3-O-acetylflavonol 27:17,35 structure of 27:35 (2R, 3R)-2,3-Dihydro-5,7,4'-trihydroxy6-methoxy-3-O-acetyl flavonol 27:18,35 structure of 27:35 4[3,6c~-Dihydro-5,7aH,8,11~Heudesma-8,12-olide 27:553 3,4-Dihydro-6,7-dimethoxy-isoquinoline 10:679-685 to chiral sulfoxides 10:679-685 to chiral sulfoximines 10:679685 3,4-D ihydro-6,7- dimethoxyisoquinoline-N-oxide 10:684 1,2-Dihydro-6c~-santonin 14:413 (1)-a-santonin from 14:413 7,8-Dihydro-7-oxo-22~hydroxytingenone 30:673 13C NMR of 30:672 DEPT of 30:672 HMBC of 30:672 HMQC of 30:672 Dihydro-8 a-hydroxybalchanin 24:77 9,10-Dihydro-9,10-dihydroxy anthracene 11:124 from anthraquinone 11:124 5,7,12,14-pentacenediquinone from 11:124 synthesis of 11:124 with acetoacetate dianion 11:124 2',3'-Dihydro-ABA 27:353 Dihydroactinidiolide 3:157,158 S-Dihydroaeruginoic acid 21:186 ~-Dihydro-agarofuran skeleton sesquiterpenes 18:775 Dihydroailanthinone 7:379,380 19,20-Dihydroakuammicine 1:32-35,54 2,16-Dihydroakuammicine 1:35 Dihydroalloevodionol 4:386,387 Dihydroalstonerine 13:398,423,424 20-21-Dihydroalstonerine 13:420-423
(+)-Dihydroanatoxin-A 13:493,494 Dihydroancyriacyanin A 12:367,372 fromArcyria nutans 12:367,372 Dihydroangustine 26:1036,1037 Dihydroanils 4:541,545 (+)- 18,19-Dihydroantirhine 14:706-708 (+)- 3 -ep i- 18,19-D ihydro antirhine 14:708 by alkaline decarboalkoxylative cyclization 14:708 from tetrahydropyridine 14:708 stereoselective 14:707,708 synthesis of 14:707,708 2,3-Dihydroapigenin 25:541 Dihydroarcyriaflavin A 12:377 Dihydroarcyriarubin B 12:366,372 Arcyria denudata 12:366,372 Dihydroarcyriarubin C 29:258 as bisindole alkaloid 29:258 Dihydroartemesinin 13:657;22:154; 26:832,833,834 19,20-Dihydroaspidospermatine 1:40 Dihydroastaxanthin diacetate 6:154 22,23-Dihydroavermectin (ivermectin) B! 12:8 from avermectin B~ 12:8 with Wilkinson's catayst 12:8 22,23-Dihydroavermectin B~ aglycones 1:443 conversion to milbemycins 1:443 22,23-Dihydroavermectin B ~b 12:17-19 aglycone of 12:17-19 Julia synthesis of 12:17-19 Dihydroavermectin B1~ 1:470 Dihydrobenzene 12:22-24 Dihydrobenzofuranols 14:651 synthesis of 14:651 via photocyclization of ketone 14:651 2,5-Dihydrobenzoic acid 23:91 Dihydrobetulinic acid 25:61 Dihydrobicyclomycin 12:65,66 16,17-Dihydrobrachycalyxolide 26:811, 812 Dihydrocaffeic acid 25:923,926 [26-3H]-Dihydrocalyesterol 9:44 [28-3H]-Dihydrocalyesterol 9:45
257
Dihydrocalysterol 9:36-38,41-45 from Calyx nicaeensis 9:37,44 from Cribrocalina vasculurn 9:37 from Petrosiaficiformis 9:37 from Petrosia hebes 9:37 20S- 1,2-Dihydrocapuvosidine 5:129 8,9-Dihydrocarotane sesquiterpene 5:728,729 Dihydrocarotol 5:734 Dihydrocarpalasionin 15:143,152, 160,174 (-)-Dihydrocarveol 29:83 activity in AM assay system 29:83 (R)-Dihydrocarvone 13:546 (+)-Dihydrocarvone 14:454;25:145, 146,147 5-epi-paradisiol from 14:454 (-)-Dihydrocarvone 5:721 d/-Dihydrocatharanthine 14:806,807,850-853 Dihydrocatharanthine 14:809,810 dihydrocatharanthinol from 14:809,810 synthesis of 5:182 15,20S-Dihydrocatharanthine N-oxide 14:870,871 decarbomethoxycatharanthine from 14:870,871 deoxyvinblastine from 14:870,871 16'-epi-deoxyvinblastine from 14:870,871 16'-epi-20'-epi-deoxyvinblastine from 14:870,14:871 vindoline-N-methylamide from 14:870,871 with vindoline 14:870,871 Dihydrocatharanthinol 14:810 from dihydrocatharanthine 14:810 3,14-Dihydrocellipticine 5:125 Dihydrocephalostatin 18:902-904 Dihydrochalcone 7:229,30,31;21:520, 522;28:234,271 aspalathin from 28:272 in apple juice 28:271 in cider 28:271
in pomace 28:271 nothofagin from 28:272 Dihydrochelerythrine 14:774,775,796 cyclization 14:774,775 from berberine 14:774,775,796 synthesis of 14:774,775,796 through enamide-aldehyde Dihydrochromones 20:282 (-)-Dihydrochrysanthemolactone 16:257-258 synthesis of 16:257-258 Dihydrocinchonamine 25:28 R-(+)-Dihydrocitronellic acid 15:231 Dihydrocitronellol 25:133 c~/[3-Dihydrocleavamine 14:806, 807,808,850,851,863,864 (-)-20S-15,20-Dihydrocleavamine 5:124 Dihydrocleavamine 5:181,182; 14:807,808 Dihydrocodeinone 18:96,98 Dihydrocompactin 13:580 19,20-Dihydrocondylocarpine 1:34 Dihydrocoptisine 6:491 ~x-Dihydrocomin 7:461 Dihydrocorphinol 9:602 Dihydrocorynantheine 22:19;25:31,32 Dihydrocorynantheol 13:92,93 (+)-Dihydrocorynantheol 18:331 Dihydrocostunolide 17:609 Dihydrocoumarin 7:205,206,225 Dihydrocubebin 17:318;26:191 (-)-Dihydrocubebin 5:753,754 23,24-Dihydrocucurbitacin F 25:59 Dihydrocurcumin 17:363 Dihydrocurecuquinone 5:767 Dihydrocycloakagerine 9:179 Dihydrocycloorbigenin 27:474 Dihydrocyclotheonamide A 26:1194, 1195,1196 Dihydrodaturalactone B 20:2462,3Dihydrodeoxyartemisinin 22:154 (+)-[3-A6-Dihydrodesoxycodeine methyl ether 18:65 Dihydrodesoxyotonecine 1:243 Dihydrodiconiferyl alcohol 27:760 polymerization of 27:760 Dihydrodidemnin 27:804 biological activity of 27:804
258 Dihydrodiisoeugenol 26:226 antibacterial activity of 26:226 11 [3,13-Dihydrodouglanin acetate 7:212,213 3,14-Dihydroellipticine 6:507,516, 518,519 Dihydroeperulic acid 25:248 Dihydroerysodine 3:478 dihydrofurans 3:55-58 from vinyloxiranes 3:55-58 synthesis of 3:478 (9S)-9-Dihydroerythromycin A 12:53,54 erthromycin A from 12:53,54 Dihydroerythromycin A 13:173-176 (9S)-9-Dihydroerythronolide A 12:53,54 ;16:718-719 erthromycin A from 12:53,54;16:718-719 erthronolide A from 12:48-53 (9S)-Dihydroerythronolide A 16:718-719 synthesis of 16:718-719 (9S)-Dihydroerythronolide A seco acid 3:478 synthesis of 3:478 Dihydroferulic acid 25:922-925 2,3-Dihydrofisetin 25:541 1ltx-Dihydroflabellin 27:579 1l~-Dihydroflabellin 27:579 Dihydroflavanoids 7:228;25:469 (+)-ampelosin 25:469 dihydromyricetin 25:469 Dihydroflavonols 15:30,31 ;22:312 Dihydroflavonol reductase 25:653 6,7-Dihydroflavopereirine 1:124,142, 143,150,153,157,158 5,6-Dihydroflavopereirine 26:1060 Dihydroflustramine C 18:691,725 Dihydroflustramine C N-oxide 18:691 Dihydrofolate reductase 7:387 Dihydrofreelingyne 15:235 Dihydrofumariline 1:198,199,207 Dihydrogambirtannine 1:158 oxidation to ourouparine 1:158 synthesis of 1:137 meso-Dihydroguaiaretic acid 26:191, 240,268,271
Dihydroguaiaretic acid 26:219,249,473 meso Dihydroguaiaretic acid 26:240 as PAF-induced inhibitor 26:240 nor-Dihydroguaiaretic acid 9:578,579 Dihydroguayaretic acid 773 Dihydrohalichondramide 17:16 11or,13-Dihydrohelenalin methacrylate 29:90 activity in NFAT assay system 29:90 activity in NFkB assay system 29:90 activity in CRO assay system 29:90 11c~,13-Dihydrohelenalin tigulinate 29:90 activity in NFAT assay system 29:90 activity in NFkB assay system 29:90 (+)- 18,19-Dihydrohunterburnine 14:706,707 (+)- 10-O-methyl- 18,19-dihydro hunterburnine from 14:706,707 synthesis of 14:706-708 with CH2N2 14:706,707 Dihydroindolizidine 11:241,243 6,7-Dihydroindolo [2,3-a] quinolizine 1:151 3,4-Dihydroisocoumarins 15:382 Dihydroisocoumarins 9:267,15:5,30, 31,381-418 Dihydroisodocarpin 15:141,149, 158,174 Dihydroisojacareubin 4:368,370 Dihydro-isokomarovine 14:762 from Nitraria komarovii 14:762 Dihydroisoosajin monomethyl ether 4:393,394 Dihydrojasmone 19:158,19:160 Dihydrojervine 23:575 Dihydrokaempferol 22:363 Dihydrokalafungin 11:128 Dihydrokamebakaurin aldehyde triacetate 15:135 Dihydrokawain 22:529,540 Dihydrokikumycin B 5:557,568 11-Dihydroklaineanone 23:301
259 Dihydrokoempferol 25:653 Dihydrokomarovinine 14:763,764 biosynthesis of 14:763,764 1,2-Dihydrokoumine 15:476 from Gelsemium elegans 15:476 5,6-Dihydrolamellarin H 23:248 Dihydrolanosterol 8:365,366 Dihydrolanosterol ester 9:467 Dihydrolevoglucosenone 14:278 Dihydrolicoisoflavone A 28:243 anti-Helicobacter pylori activity of 28:243 (+)-Dihydrolimonene 6:541,542;8:227 ozonization of 6:541 (-)-periplanone-B from 6:541, 542 2,3-Dihydroluteolin 25:541 3,4-Dihydromanzamine A 21:260, 261,262 Dihydromarthasterone 7:289;15:51 Dihydromethysticin 22:529,540 Dihydromevinolin 13:575,608,609 synthesis of 13:575,608,609 3,4-Dihydromilbemycin E 16:659 from Streptomyces sp. 16:659 Dihydromyoporone 1:604,606 9-Dihydromyoporone 15:229 7S,9R-(-)-9-Dihydromyoporone 15:230 Dihydronapthalenes 24:743,744,765 from oxidative coupling 24:743, 744 of 2,3-dibenzylbutyrolactones 24:744-754 synthesis of 24:765 Dihydronepetalactone 7:477;16:289 (+)Dihydronepetalactone 20:71 3,6-Dihydronicotinic acid 11:206 Dihydronitidine 14:775,776 Dihydronitraraine 14:765 from (S)-glyceraldehyde 14:765 synthesis of 14:765 2,3-Dihydro-N-methylacronycine 13:359 Dihydronodularin 9:496 from nodularin 9:496 (+)-7,8-Dihydronogarene 14:68 7,8-Dihydronogarene 14:78 Dihydronorfluorocurarine 1:46-48 22-Dihydrooccelasterol 9:41
Dihydro-O-methylmacusine B 13:387 Dihydroonychine 2:442 Dihydroparfumidine 1:206-209 Dihydroparthenolide 27:565 Dihydropenicillic acid 26:449 Dihydroperaksine 13:387 Dihydroperezine 5:766,767 Dihydroperillic acid 29:83 activity in RAS assay system 29:83 Dihydroperoxides 9:560 5,6-Dihydro-PGI2 25:595 Dihydrophenanthrenes 20:280 Dihydrophenanthridines 4:541 Dihydrophenoxazine 26:976 Dihydrophymaspermones 15:233 (25S) 25,27Dihydrophysalin A 20:189 Dihydropinidine 1:391,392 (+)-Dihydropinidine 14:572,573 (-)-Dihydropinidine 16:482 2,3-Dihydropiperidine 19:45 Dihydroprotoberberines 14:771-773 Hofmann degradation of 14:771-773 (+)-Dihydroprotoemetine 18:330 (+)-20R- 18,19-Dihydropseudovincadifformine 5:124 Dihydropseurata F 15:117,124,131,174 Dihydropyran 12:158 Dihydropyran derivative 10:425 Dihydropyranocoumarins 18:984 Dihydropyridine receptor 21:17 Dihydropyridines 1:91,92;25:534 Dihydropyridinium 21:308 Dihydropyrrole 10:112,113 synthesis of 10:112,113 2,3,-Dihydroquercetin 25:541 (2R,3R)-Dihydroquercetin (toxifolin) 5:496 Dihydroquercetin 3-acetate 4'-(methyl ether) 15:26 (+)-Dihydroquercetin 3-O-acetate 15:31 Dihydroquercetin 3-O-acetate 4'-methyl ether 27:17,35 structure of 27:35 (2R, 3R)-Dihydroquercetin 3-O-acetate 27:17,34,35 structure of 27:35 Dihydroquinone uncinatone 7:408,423
260
Dihydroridentin 27:567 Dihydrorugosanin 15:142,150,159,174 Dihydrosampangine 23:35 Dihydrosanguinarine 14:793-795 from coptisine 14:793-795 structure of 27:173 synthesis of 14:793-795 through cationic cyclization 14:793-795 bis( 6-Dihydrosanguinarinyl) ether 27:172 bond length & angles in 27:175 crystal data of 27:175 structure of 27:172 X-ray analysis of 27:174 11or,13-Dihydrosantamarin 7:213 1,2-Dihydrosantonin 26:463 Dihydroschelhammeridine 3:484-486 synthesis of 3:484-486 6',7'Dihydro-scutionin ctB 30:685,686CD-spectrum of 30:685 structure of 30:686 Dihydrosecodine 19:90 15,20-Dihydrosecodine 19:91 Dihydrosecurinine 14:657 Dihydroserratenone 11:309 Dihydrosiphonarin A and B 17:25 Dihydrosirohydroochlorin 9:603 Dihydrosolanidine 23:575,584 Dihydrosolasodine 23:575,585 Dihydrosphingosine 18:786 Dihydrospiniferin-1 derivative 6:72 by Birch reduction 6:72 by electrocyclic rearrangement 6:72,73 by Jones oxidation 6:72 by Simmons-Smith cyclopropanation 6:72 from 6-methoxy-l-tetralone 6:72 Marshall synthesis of 6:72,73 Dihydrostemmdenine acetate 1:49 19,20 (-)-11,12-Dihydrostepharine 2:254,258 (+)- 8,9-Dihydrostepharine 2:254,258 20,21-Dihydrostrychnobrasiline 26:1065 Dihydrosweroside 26:104 8,10-Dihydrosweroside aglucone 26:141
20'S- 19',20'-Dihydrotabemamine 5:128 Dihydrotachysterol 4:521-526 synthesis of 4:521-526 Dihydrotanshinone 22:175 (11R)-I 1,13-Dihydrotatridin A 27:571 (11R)-I 1,13-Dihydrotatridin B 27:571 Dihydroteugin 23:609 Dihydrothebainone 18:59 (+)-Dihydrothebainone 18:70,72,73, 77,78 Dihydrothiopyrans 8:207 Dihydrothiopyrone 8:207,208 synthesis of 8:207,208 Dihydrotubastrine 5:360 Dihydroudoteal 18:688 3,4-Dihydroumbelliferone 4:400 12,13-Dihydroursolic acid 9:293,294 5',6'-Dihydrousambarensine 26:1062, 1063 anticancer activity of 26:1060 18,19-Dihydrousambarine 26:1062 anticancer activity of 26:1060 ot-Dihydroverbenol 7:461,462,467,468 Dihydrovincarpine 1:124 Dihydrowisanine 24:704 2,3-Dihydrowithaferin A 20:181, 194,214 Dihydroxanthommatin 26:988,989 3',4'-Dihydroxiflavone 26:757 Dihydroxy phenolic lipids 30:116 umshiol-type 30:116 1ct-25-Dihydroxy-(24R)-fluorocholecalciferol 10:57,69 3,6-Dihydroxy- 1,7-dimethoxyxanthone 30:622 3c~,13-Dihydroxy- 11-epi-apotrichotec-9ene 9:210 3[3,13-Dihydroxy- 11-epi-apotrichotec-9ene 9:210 2ct, 13-Dihydroxy- 11-epiapotrichothecene 13:520 2[3-13-Dihydroxy-11-epiapotrichothecene 13:520 10-Dihydroxy- 11-methoxydracaenone 5:17,18,20,22,556 ent- 12or,16-Dihydroxy- 13 [R]-imar8(14)- ene-3,15- dione 9:283,284
261
1,3-Dihydroxy-2-( 1'-oxotetradecyl)benzene 30:133 struture of 30:133 3,4'-Dihydroxy-2,3'-bipyridine 2:239,753 1,5-Dihydroxy-2,3-dimethoxy- 10methylacridin-9-one 13:348,350,355 from Glycosmis bilocularis 13:348,350,355 synthesis of 13:354,355 (2S)-2,4' Dihydroxy-2"-( 1-hydroxy- 1methylethyl)-dihydrofuro[2,3h]flavanone 28:17 as aromatase inhibitor 28:17 20,22f3-Dihydroxy-20-epi-tingenone 30:669 20,21 a-Dihydroxy-22-oxo-21desoxotingenone 30:669 NMR experiments of 30:669 NOE experiments of 30:669 structure of 30:669 2,3-Dihydroxy-24-norfrieadela-l,3,5,7 tetraen-29-oic acid 25:59 diacetoxy derivatives 25:59 (22R,23 R,24 S)-22,23-D ihydroxy- 28homoergosterol 18:520 2,4-Dihydroxy-2H- 1,4-benzoxazin3(4H)-one-skeleton 27:194-196 1,3-D ihydro xy-2-he xadec ylb enzene 30:129 structure of 30:129 1,3-Dihydroxy-2-hexyl-5-pentylbenzene 30:137 structure of 30:137 4,4'-Dihydroxy-2-methoxy-5-(c~,otdimethylallyl)-chalcone 21:741 1,3-Dihydroxy-2-methyl-5tridecylbenzene 30:126 structure of 30:126 (22 R, 23 R,24 R)- 22,23-D ihydroxy2~,3 c~-epoxy-24-methyl-5 ~cholestan-6-one 18:512 2,13-Dihydroxy-3,11-epoxy APO 13:522 6 a,25-Dihydroxy-3,16-dioxo-9fl,19cyclolanestane 25:184
213,2213-Dihydroxy-3,21-dioxo-24carboxyl-29-nor-ffiedelan methyl ester 30:641 structure of 30:641 4,5-Dihydroxy-3,3,6, 7,8pentamethoxyflavone 30:742 (R)-2,4-Dihydroxy-3,3-dimethylbutanoic acid 10:442,443 5,3-Dihydroxy-3,6,7,4',5'-pentamethoxyflavone 5:757 1,3-Dihydroxy-3,7-dimethytoct-6-ene-2one 25:134 3 [3,20~-Dihydroxy-30-novolenan- 12-en28- oic acid 7:139,140 1,5-Dihydroxy-3-methoxy- 10methylacridin-9-one 13:348,350 2 ',5 '-Dihydroxy- 3-nitrophenylac etic acid 26:592 2c~,19c~-Dihydroxy-3-oxo- 12-ursen-28oic acid (ursane triterpene) 29:574 effects on HIV-1 protease 29:574 4c~,10~-Dihydroxy-3-oxo-8 []-isobutyryloxyguaia- 11(13)-en- 12,6c~-olide 29:90 2,2213-Dihydroxy-3-oxo-olean- 1,12dien-29-oic acid 30:651 13C NMR spectrum of 30:650 IH NMR spectrum of 30:650 HMBC spectra of 30:650 molecular formula of 30:650 structure of 30:651 ent- 13 [S], 14 [S]-Dihydroxy-3-oxo-tis- 15en-17-al 9:268,269,276 1,2-Dihydroxy-3-pentadecyl benzene 9:314,318,343 6,8-Dihydroxy- 3-undec yl-3,4dihydroisocoumarin 15:386 3,6-Dihydroxy-4,5,7-trimethylmellein 15:385 2,6-Dihydroxy-4-methoxyacetophenone 4:386,387 1,3-D ihydroxy- 5- (2 '-hydro xy- 8 'oxotridecyl)benzene 30:131 structure of 30:131 10S, 11R-Dihydroxy-5 (6), 15-rosanedien7-one 20:474
262
1,3-Dihydroxy-5-(nonadec-8Z, 11Zdienyl)benzene 30:125 structure of 30:125 1,3-Dihydroxy-5-(none-2Z-enyl)benzene 30:124 structure of 30:124 3,6-Dihydroxy-5,7-dime thylmellein 15:385 4[3,6c~-Dihydroxy-5,7 c~H,813Heudesman-8,12-olide 27:552 3,10-Dihydroxy-5,8-diacetoxy- 1(2), 1 l(12)-dehydrofamesol 27:586 1,3-Dihydroxy-5 -alkylbenzenes 9:320,321 1,3-Dihydroxy-5-heneicosyl benzenes 9:343 1,3-Dihydroxy-5-hexyl-2-propyl benezene 9:322 1,3-Dihydroxy-5-isotetradecylbenzene 30:130 structure of 30:130 1,3-Dihydroxy-5-nonadecyl benzene 9:343 1,3-Dihydroxy-5-pentyl benzene (olivetol) 9:344 1,3-Dihydroxy-5-tridecyl benzene 9:344 1,3-Dihydroxy-5-tridecyl benzene from 9:344 313,6c~-Dihydroxy-5c~-pregn-9(11)-en20-one 7:156,157;15:45 2o~,313Dih y dro x y- 5 et-pre gnane-6,20dione 18:530,18:534 2,4-Dihydroxy-6-(1-oxooctyl)benzoic acid 30:134 structure of 30:134 5,4'-Dihydroxy-6,7,3'-trimethoxyflavone 5:653,655 5,4'-Dihydroxy-6,7,8,3'-tetramethoxyflavone 5:653,5:655 5,4'-Dihydroxy-6,7,8-trimethoxyflavone 5:653 3,4,'-Dihydroxy-6,7-dimethoxyflavone 5:14,15 5,8-Dihydroxy-6,7-dimethoxyflavone 5:624,627,628,640 5,4'-Dihydroxy-6,7-dimethoxyflavone 5:653,657
213,413-Dihydroxy-6-deoxy-celorbicol 18:744 5,7-Dihydroxy-6-methoxyflavonoid 5:640 11,12-Dihydroxy-6-oxo-8,11,13abietatriene 29:99 activity in COX assay system 29:99 1[3,4c~-Dihydroxy-6a-angeloyloxyeudesm- 11(13)-en-8,12-olide 27:552 113,4c~-Dihydroxy-6o~-isobutyloxyeudesm- 11 (13)-en-8,12-olide 27:552 5,6-Dihydroxy-7,3',4'-trimethoxyflavone 5:655 5,6-Dihydroxy-7,4'-dimethoxyflavone 5:623,653 5,6-Dihydroxy-7,8,3',4'-tetramethoxyflavone 5:655 5,6-Dihydroxy-7,8,4-trimethoxyflavone 5:629,653 15c~,22[3-Dihydroxy-7,8-dehydrotingenol 30:682 ~3C-NMR data 30:682 structure of 30:682 7,8-Dihydroxy-7,8-dihydrobenzo [ 1] pyrene 9:583 7,8-Dihydroxy-7,8-dihydro-vitamin D2 9:522 5,6-Dihydroxy-7,8-dimethoxyflavone 5:624-629,640 9,10-Dihydroxy-7-methoxynaphtho [2,3-c] pyran-l(1H)-one (semivioxanthin) 11:130 antibiotic activity of 11:130 antifungal activity of 11:130 1[3,3[3-Dihydroxy-7ot, 11 [3H-germacra4Z- 10(14)-dien-12,6ct-olide 27:562 1,3[3-Dihydroxy-7a, 11 [3H-germacra4Z,9Z-dien- 12,6o~-olide 27:562 1a,3 [3-Dihydroxy-7c~, 11 [3H-germacra4Z,9Z-dien- 12-6c~-olide 27:561 5,11-Dihydroxy-8,9-dihydro-9,10dehydronerolidol 27:587 2o{,4[~-Dih ydro xy- 8-ep i-cel apano I 18:746
263
5,7-Dihydroxy-8-methoxyflavonoid 5:640 1c~,313-Dihydroxy-9[3,10[3-epoxy7a, 11 [3H-germacra-4Z-en- 12,6o~olide 27:562 7(x, 15-Dihydroxyabieta-8,11,13-trien18-al 29:99 activity in EBV assay system 29:99 from Larix kaempferi 29:99 15,18-Dihydroxyabieta-8,11,13-trien-7one 29:99 activity in EBV assay system 29:99 18-nor-4ct, 15-Dihydroxyabieta-8,11,13trien-7-one 29:99 activity in EBV assay system 29:99 15,18-Dihydroxyabieta-8,11,13-trien-7one-18-acetate 29:99 activity in EBV assay system 29:99 2~-23-Dihydroxyacacic acid 21:643 1,3-Dihydroxyacridin-9-one 13:355,358 9,11-Dihydroxyacronycine 13:366,367 (+)-3,9-Dihydroxyaporphine 16:518 ent- 13 IS], 15 [3-Dihydroxyatis- 16-ene3,14-dione 9:268,269 ent- 13 [S], 18Dihydroxyatis- 16-ene-3,14ione 9:268,269,276,282ent-3 [3,13[S]-Dihydroxyatis-6-ene- 14one 9:268,269,276,280 ent- 16c~,17-Dihydroxyatisan-3-one 9:68,269,276,9:277,168,169,176 1,3-Dihydroxybenzene 14:655 dichlorination of 14:655 with sulfuryl chloride 14:655 3,4-Dihydroxybenzoate 22:322 2,5-Dihydroxybenzoic acid 21:617 2,4-Dihydroxybenzoic acid 2,4-Dihydroxybenzoic acid 4:395,398; 21:7412 Dihydroxybenzoic acid 26:337 2,5-Dihydroxybenzyl 27:870 for inhibitory activity 27:870 2ot,3 [3-Dihydroxy-B-homo-6a-oxa-5etpregnane-6,20-dione 18:530
1ot,25-Dihydroxycalciferol (calcitriol) 9:20,521 Dihydroxychalcones 22:420 1et-25-Dihydroxycholecalciferol-26,23 (S)-lactone 10:59 synthesis of 10:59 20,22-Dihydroxycholesterol 21:309 Dihydroxychromone 21:147 3,4-Dihydroxycinnamate 22:322 Dihydroxyconiferyl-alcohol 25:657 6,7-Dihydroxycoumarin 27:847 7,8-Dihydroxycoumarin 27:847 7,8-Dihydroxycoumarin 4:372,373 3 [3,29-Dihydroxy-D: f3-frie do- o lean- 5ene 5:747 2c~,14-Dihydroxydehydroabietic acid 20:669 Dihydroxyethylated rutoside 22:320 (S)-(-)-I 0,11-Dihydroxyfarnesol 25:166 5,4'-Dihydroxyflavone 25:541,544 5,7-Dihydroxyflavone 25:541,544 3,2'-Dihydroxyflavone 29:572 effects on HIV- 1 protease 29:572 5,8-Dihydroxyflavonoid 5:625,627, 628,658 5,6-Dihydroxyflavonoid 5:625627,629,658 3,4-Dihydroxyflavonoid aroxyl 22:322 5,8-Dihydroxyflavonols 5:627 28,29-Dihydroxyfriedelan-3-one 7:150 1,4-Dihydroxy- germacra- 5E- 10( 14)diene 29:88 activity in CRO assay system 29:88 Dihydroxyheliotridane 1:246,252, 253,52 synthesis of 1:246,252,253,52 1,2-Dihydroxy-hexahydro-3 ( 2H)indolidinones 12:305 3,4-Dihydroxyhomoisoflavan 5:21,22 1,2-Dihydroxyindolizidine 12:303-306 (+)-( 6R,7S, 8aR)-Dihydroxyindolizidine 12:306 6,7-Dihydroxyindolizidine 12:348 from methyl 2-azido-4,6-Obenzylidene-2-deoxy-c~-D-
264 altropyranoside 12:348 synthesis of 12:348 Dihydroxyindolizidine 27:525 from natural sources 27:525 1tx,6c~-Dihydroxyisocostic acid methyl ester 27:557 5,7-Dihydroxyisoflavone 4:382,385 4'-O-methylosajin from 4:382,385 4'-O-methylwaranglone from 4:382,385 with 3,3-dimethylallyl bromide 4:382 14,15[3-Dihydroxyklaineanone 23:301 6,7-Dihydroxylate coumarin 5:516, 517,520 Dihydroxylation 11:423,424 cis-Dihydroxylation 16:332 of AZZ-stigmasterol 16:332 of brassicaterol 16:332 of ergosterol 16:332 (-)-3,13 a-Dihydroxylupanine 15:523 from Cytisus scoparius 15:523 15 2,5-Dihydroxymethyl-3,4dihydroxypyrrolidine(DMDP) 7:13 2R,5R-Dihydroxymethyl-3R,4Rdihydroxypyrrolidine 10:545,546 absolute configuration of 10:545,546 almond emulsin D-glucosidase inhibitor of 10:545 enantioselective synthesis of 10:546,547 from Derris elliptica 10:545 from Lonchocarpus sericeus 10:545 from Omphalea diandra 10:545 [3-galactosidases 10:545 [3-glucosidases 10:545 insect trehalase inhibitor of 10:545 relative configuration of 10:545,546 yeast invertase inhibitor of 10:545 yeast ot-glucosidase inhibitor of 10:545 2-Dihydroxymintlactone 26:456
3,11-Dihydroxymyristic acid 13:312 1,8-Dihydroxynaphthalene 21:208 10,11-Dihydroxynerolidol 25:163 (6R,7R)-6,7-Dihydroxynonan-2-one 11:413,414 3c~,28-Dihydroxy-olean-12-en-29-oic acid 30:649 3 [3,28-Dihydro xy-o lean- 12-en-29-o ic acid 30:649 6,5-Dihydroxyperezone 5:795,796 Dihydroxyphenolic compounds 25:657 L-3,4-Dihydroxyphenylalanine 27:754 from peroxidase 27:754 D-(-)-3,4-Dihydroxyphenylglycine 27:754 from peroxidase 27:754 3,4-Dihydroxyphenyllactic acid 30:216 3 [3,4~-Dihydroxypregn-5-en-20-3sulfate 28:704 5-pregnene skeleton of 28:704 20R- 18,19-Dihydroxypseudovincadifformine 9:190 Dihydroxyserrulatic acid 15:257 from Eremophila serrulata 15:257 3,11-Dihydroxystaurosporine 12:366,370 fromEudistoma sp. 12:366,370 (22R,23R)-22,23-Dihydroxystigmasterol 18:515 Dihydroxythymoquinone 5:776 20,2213-Dihydroxytingenone 30:669
8ct,9~-Dihydroxy-trans,trans-germacra1(10),4(5)-dien-trans-6,12-olide 27:563 14,15-Dihydroxyvincadifformine 5:124 l(x,25-Dihydroxyvitamin D 30:485 structures of 30:485 1,24-Dihydroxyvitamin D2 9:513 1,25-Dihydroxyvitamin D2 9:513 24,25-Dihydroxyvitamin D2 9:513 24,26-Dihydroxyvitamin D2 9:513 25,26-Dihydroxyvitamin D2 9:513 1c~,25-Dihydroxyvitamin D2 (ercalcitriol) 11:393-395 synthesis of 11:393-395 24R-epimer of 11:393-395
265
1Gt,24R-Dihydroxyvitamin D3 11:384,385 synthesis of 11:384,385 1c~,24S-Dihydroxyvitamin D3 11:384,385 synthesis of 11:384,385 1c~,25-Dihydroxyvitamin D3 9:12,514, 516,519;11:379,380,385,395 ;20:669; 30:484 effect on bone maturation 30:484 effect on calcium metabolism regulation 30:484 effect on immune responsiveness 30:484 effect on malignant cells differentiation 30:484 synthesis of 11:384,385,388-423 24R,25-Dihydroxy-vitamin D3 9:512, 514 6tx,7[3-Dihydroxyvouacapan-1713-oic acid 29:103 activity in AOS bioassay system 29:103 1,3-Dihydroxyxanthone 22:664,665 1,7-Dihydroxyxanthone 5:759 2,3-Dihydroxyxanthone 5:759 Dihydroyashabushiketol 26:883 Dihydroyohimbine 15:487 3,4-Dihydro-[3-carboline 13:489,490 Dihydro-13-carboline 8:287,288 Dihydro-[3-cyclo-pyrethrosin 27:554 Dihydro-[3-erythroidine 21:52 20R- 1,2-Dihyrocapuvosidine 5:123125,127,131,129 (+)-20R-15,20-Dihyrocleavamine 5:124 3,8-Dihyroxy-gluco side-2hydroxymethy lanthraquinone 26:657 3,5-Diidotyramine 23:234 Diindole 12:382,383 3'-7,y-Diinethylallylwighteone 25:541 3,5-Diiodo-L-tyrosine 10:653,661,667 Diisobutyl aluminum hydride (DIBAL-H) 1:523,324,353;4:589, 590;22:203,226,228 Diisobutylaluminium 6:115 Diisobutylaluminum hydride-Nbutyllithium "ATE"complex 14:595
7,20-Diisocyanoadociane 21:330 Diisocyanoadociane 21:350,367 7,20-Diisocyanoadociane 6:86,87 by intramolecular [4+2] cycloaddition 6:86,87 by stereospecific intramolecular Diels-Alder cycloaddition 6:86,87 by vinylation 6:86,87 by Wittig coupling 6:86,87 enantioselective synthesis of 6:86,87 fromAdocia species 6:86 from (1R,2S,5R)-(-)menthol 6:86 (+)-Diisopinocamphenylborane 20:587 Diisopropyl (bromomethyl) boronate 11:425 synthesis of 11:425 Diisopropyl aprotinin 30:836 N,N-Diisopropyl carbamoyl chloride 10:15 Diisopropyl ethanediol esters 11:415417 insect pheromones II from 11:415-417 Diisopropyl fluorophosphase (DFP) 30:843 Diisopropyl tartarate 12:282,19:445 3,7-Diisopropyl- 1-azulenecarbaldehyde 14:337,340 Diisopropylamine 12:113 Diisopropylamine borane 4:437 in stereoselective reduction 4:437 Diisopropylethanediol (DIPED) 11:415 (S,S)-Diisopropylethanediol methyl boronate 11:415,416 ( R, R )-D iisoprop yl e thanedi o l
propylboronate 11:415 Diisopropylethylamine 12:46,47 N,N-Diisopropylphosphoramidites 18:398 1,4-Diisothiocyanatobenzene 26:481 [3-Diketone 6:48 in (+)-A9<~Zkcapnellene synthesis 6:48 photochemical annulation of 6:48
266
c~-Diketone 8:165,166 synthesis of 8:165,166 1,3-Diketone enolates 3:74,75 1,4-Diketones 6:437,438 2,5-dialkyl pyrrolidines from 6:437,438 reductive amination of 6:437,438 Diketopiperazines 10:638,96,97,321; 21:310,323,218,221 ;25:901 ;28:362 containing dioxepinoindole ring 28:362 2,2'-Diketospirilloxanthin 20:594 Dilactone 6:301,303 synthesis of 6:301,303 Dilactonic clerodane-diterpene 30:748 Dilaspiralactone 4:712 Dilignan 5:497,498 Dilignols 5:464-466 Dilithium (cyano) dimethyl cuprate 11:361 Dilithium (cyano) divinyl cuprate 11:360,361 Di-/-menthol (acetoxymethylene) malonate 13:66 Dilodia gossypina 25:131,149 Dilophus 25:690 Dilophus ligulatus 25:690 Dilophus okamurai 25:690 DIMBoA 27:213,214 in tritrophic interaction 27:213, 214 Dimeric anthracenones 22:557 Dimeric aporphine 30:584 Dimeric coniferyl alcohol derivatives 27:592 Dimeric tetrahydroisoquinolines 21:57 Dimeric triterpenes 18:764-709 Dimerization 26:532 of resveratrol 26:532 Dimers 26:544,545,546,547,548,549 ampelopsin D&F 26:544 anigopreissin A 26:544 betulifol A&B 26:545 gnetin A&C 26:546 gnetin F&G 26:546,547 leachianol G 26:547 malibatol A 26:547 parthenocissin A 26:548 restrytisol A-C 26:548,458
tricuspidatol A 26:549 viniferifuran 26:549 (+)-e-viniferin 26:545 Dimethomorph 9:226 1,3-10,11-Dimethoxy indolines 9:185,186 1R- 1-Dimethoxy phosphenyl-D-threitol 6:355 3,3-Dimethoxy- 1-(phenylsul fonyl)propane 30:470 (+)-(2R,3 R)- 1,4-Dimethoxy-2,3butanediol 14:499,14:500 1,4-Dimethoxy-2,4 ',4"- trihydrox y-pterphenyl 29:267 as cytotoxic principle 29:267 2-( 4,5-Dimethoxy-2-nitrobenzyl)20-hydroxyecdysone 29:19 as synthetic ecdysteroid analogues 29:19 3,4 '-Dimethoxy-3 ', 5,7trihydroxyflavone 30:728 structure of 30:728 2,4-Dimethoxy-3-methyl-phenol 13:437,438 1,2-Dimethoxy-4-(E-3'-methyloxiranyl) benzene 26:362 2,6-Dimethoxy-4-hydroxyacetophenone 4:386,387 2,3-Dimethoxy-4-pyridyl-N,Ndiisopropyl carbamate 21:214 Dimethoxy-5-(7-hydroxyheptyl)benzene 9:345 1,3-Dimethoxy-5-( 9-phenylnonyl)benzene 30:135 structure of 30:135 1,3-Dimethoxy- 5- (unde c- 3Zenyl)benzene 30:127 structure of 30:127 3,4- Dime thoxy-6-(2'N,N-dimethylaminoethyl)-5-(methylthio)benzotrithiane 25:833 2,12-D imetho xy-6,7,8,9-tetrahydro- 5-Hdibenz [d,f] azonine-3,11-diol 6:478 synthesis of 6:478 Dimethoxyabieta-8,11,13-triene 14:676, 677 demethoxylation of 14:676,677 to taxodione 14:676,677 transformation of 14:676,677
267 Dimethoxyabietatriene 14:697,698 10,11-Dimethoxyacronycine 20:792, 798 5,7-Dimethoxyanthracene 11:120 Dimethoxyanthracene 11:126 Claisen condensation of 11:126 5,5'-dipentacene 14,14' (5H,5'H) dione from 11:126 with methyl acetoacetate dianion 11:126 with Pb (OAc)2 11:126 Dimethoxybenzaldehyde 9:343,354 Dimethoxybenzene 14:670-674,681,682 1,3-Dimethoxybenzene 4:389 3,4-Dimethoxybenzoic acid 26:1013 3,5-Dimethoxybenzoic acid 9:344 2,6-Dimethoxybenzoquinone 23:341,797 3,5-Dimethoxybenzoyl chloride 9:344 N-(2,4-Dimethoxybenzyl) tirandamycin 14:138 (-)-trans-2-( 3 ,4-Dimetho x ybenzyl )- 3(3,4-methylene-dioxybenzyl)T-butyrolactone 18:556 4,4-Dimethoxybutyronitrile 6:319 1,11-Dimethoxycanthin-6-one 7:389,390 10-11-Dimethoxycoronaridine (conopharyngine) 9:174,176,177 (2R)-5,6-D imetho xydehyrois o-cxlapachone 20:494 Dimethoxyethane (DME) 8:16,166 6', 8'-Dimethoxyfeselol 27:592 5,7-Dimethoxyflavone 5:413,652 3,5-Dimethoxyfluorobenzene 9:346 ix,ct-Dimethoxylation 3:474 1,8-Dimethoxynaphthalene glutarate 11:120 Dimethoxyolivetol 19:187 3,4-Dimethoxyphenethyl alcohol 12:448 3,4-Dimethoxyphenol 8:170 anodic oxidation of 8:170 (3,4-Dimethoxyphenyl) methyl methyl ketone 6:334 from veratraldehyde 6:334 methyl-DOPA from 6:334
8-(3,5-Dimethoxyphenyl) octan- 1-ol 9:339 synthesis of 9:339 2-( 3',4'-Dimethoxyphe nyl)- 1,3-thian 12:466 3,4-Dimethoxyphenylacetone 30:219 condensation of 30:214 reactions of 30:219 2,3-Dimethoxyphenylethanal 30:215, 216 3,4-Dimethoxyphenylethanal 30:215 3,4-Dimethoxyphenyl- O-D-glucoside 27:410 3,4-Dimethoxyphenylpropionic acid 12:448 3,4-Dimethoxypyridine 21:214 2,5-Dimethoxytetrahydrofuran 19:18,19 2,6-Dimethoxytoluene 13:437,438,448 Dimethoxytrityloxyethylsulfonylethyl 4:285 Dimethyl (methylthio) sulfonium triflate (DMTST) 10:467 Dimethyl 2-amino- 1,3-azulenedicarboxylate 14:339 Dimethyl 2-amino-6-formyl- 1,3azulenedicar-boxylate 14:339 Dimethyl 3,5,10,13-tetraoxotetra decanedioate 11:116 Dimethyl 6-substituted 3,5,9,11tetraoxodo-decanedioatel 1:118 Dimethyl azodicarboxylate 22:211 3,5-Dimethyl benzylalcohol 9:225 2,2-Dimethyl chromanes 9:115,116 Dimethyl diazene 22:196 Dimethyl ketal 11:347 2',6'-Dimethyl L-tyrosine (Dmt ~) 30:801 Dimethyl N-boc-threo-f3-hydroxy-Lglutamate 12:431,432 Dimethyl phosphorochloridite 18:399402 Dimethyl polysiloxane 9:454,456 (R, R)-2,5-Dimethyl pyrrolidine 14:555,556 Dimethyl sulfoxide (DMSO) oxidation 10:413,414 4,4-Dimethyl thiazolidin-2-thione derivative 12:164,166 Dimethyl thiosulfinate 23:467
268
3,7-Dimethyl-(E)-2,6-octadien-l-ol 25:132 4,6-Dimethyl- 1,3-cyclohexadiene 6:83,84 2,8-Dimethyl- 1,7-dioxaspiro [5.5] undecane 1:692 3,7-D imethyl- 1,7-octanedio1 25:133,136 2,6-Dimethyl-l,8-octanediol 25:135,138 12,7-Dimethyl- 1,1,6-dioxaspiro [4.4]nonanes 19:129 1,2-Dimethyl- 1-carboxymethyl-2-phenyl cyclopentane 8:13 6,7-Dimethyl- 1-hydroxyxanthone 5:759 4,4-Dimethyl- 1-mesityl-2-pentyn- 1-one 14:615 1,2-Dimethyl- 1-phenyl cyclopentane 8:6,7 cis- 1,2-Dimethyl- 1-phenyl cyclopentane 8:8 trans- 1,2-Dimethyl- 1-phenyl cyclopentane 8:8,9 4,7-Dimethyl-2-(4,6,, 8-trimethyl- 1azulenyl)- 1H-inden- 1-ones 14:342 (2E,5 E)-3,7-Dimethyl-2,5-octadiene1,7-diol 25:138 (Z)-2,6-Dimethyl-2,7-octadiene- 1,6,-diol 25:138,142 (E)-2,6-Dimethyl-2,7-octadiene- 1,6,diol 25:142,138 1,3-Dimethyl-2-arylnaphthalenes 30:217 3,5-Dimethyl-2-cyclohexan- 1-one 6:82,83 (+)-9-isocyanopupukeanane from 6:82,83 5,5-Dimethyl-2-cyclpentenone 13:16 (Z)-2,6-Dimethyl-2-octene- 1,8-diol 25:136 (E)-2,6-Dimethyl-2-octene- 1,8-diol 25:138 (Z)-3,7-Dime thyl-2-octene- 3,8-dio1 25:138 (E)-3,7-Dimethyl-2-octene-l,8-diol 25:138 4,4-Dimethyl-2-oxazolidone derivative 12:164,166
1,3-Dimethyl-2-oxohexahydrop yrimidine 8:316,343 1,3-Dimethyl-2-phenylnaphthalene skeleton 30:219 2,5-Dimethyl-3-(1-hydroxyisopentyl)-6(1-oxoisopent-2-enyl)-pyrazines 5:227,247,266 2,5-Dimethyl-3-( 1-oxoisopentyl)- 6-( 1hydroxyisopentyl)-pyrazines 5:226,246,247,266 2,5-D imethyl-3-( 1-oxoisopentyl)- 6-( 1oxoisopent-2-enyl)-pyrazinesm 5:226,247,266 2,5-Dimethyl-3-(2-methylbutyl)pyrazines 5:224,228,230,231,243, 244,259,260 2,5-Dimethyl-3,6-di(1-hydroxyisopentyl) pyrazines 5:226,246,247 2,5-Dimethyl-3,6-di-(1-oxoisopentyl) 5:226,246,247,266 2,5-Dimethyl-3,6-diisopentylpyrazine s 5:225,227,229,246 2,5-Dimethyl-3,6-dimethylpyrazines 5:225,227,236 (2S*,3S*,6R*) 2,6-Dimethyl-3,6-epoxyocta-7-enoic acid 27:594 2,6-Dimethyl-3-alkylpyrazines 5:227,237,238 2,5-Dimethyl-3-alkylpyrazines 5:227 2,5-Dimethyl-3-citronellylpyrazines 5:225,230,239,246,261 2,5-Dimethyl-3-ethylpyrazines 5:222,225,231-237,249-251 2,6-Dimethyl-3- ethylpyrazine s 5:223,237,238 2,5-Dimethyl-3-isobutylpyrazines 5:223,228,230-232,238 2,6-Dimethyl- 3-i sobutylp yrazine s 5:223,237,238 2,5-Dimethyl- 3- isopentyl- 6-( 1-hydroxyisopentyl)-pyrazine 5:226, 246,247,266 2,5-Dimethyl-3-isopentyl-6-(E-isopent1-enyl)-pyrazines 5:226,245 2,5-Dimethyl-3-isopentyl-6-(isopent-2enyl)-pyrazines 5:226,245,266 2,5-Dimethyl-3-isopentylpyrazines 5:223,224,227-233,237,238,240, 243,244,246,251,259-261
269 2,6-Dimethyl-3-isopentylpyrazines 5:224,227,237 2,5-Dimethyl-3-methylpyrazine s 5:222, 228,232-237 2,5-Dimethyl-3-n-alkylpyrazines 5:232-237 2,5-Dimethyl-3-n-butyl-pyrazines 5:224,232,237,238 2,6-Dimethyl-3-n-hexylpyrazine 5:225,237,238 2,5-Dimethyl-3-n-pentylpyrazines 5:225,228,232,259,260 2,6-Dimethyl-3-n-pentylpyrazines 5:225,237,238 2,5-Dimethyl-3-n-propylpyrazines 5:223,228,229,232, 233,240 2,6-Dimethyl-3-n-propylpyrazines 5:223,232,237 3,7-Dimethyl-3-phenyl-7-octene 8:10 cyclization of 8:10 2,5-Dimethyl-3-phenylethylpyrazine 5:257 2, 6-D ime th y l- 3 -s ec-butyl-p yrazines
5:223,237,238 2,5-Dimethyl-3-sec-butyl-pyrazines 5:223,238 (3S,4R)-3,7-Dimethyl-4-hydroxyo ct-6enoic acid 11:414 3,3-Dimethyl-4-pentenoic acid 22:203 2,3-Dimethyl-5-isobutylppyrazines 5:223,227,232 2,2-Dimethyl-5-nitromethylpyrrolidin- 1ol 12:284 (E)-3,7-D imethyl-5-oc tene-1,7-diol 25:138 (E)-2,6-Dimethyl-6-hydroxy-2,7octadienoic acid 25:140 3,7-Dimethyl-6-octene-l-al 25:132 3,7-Dimethyl-7-octene-l,6-diol 25:138 3,3-Dimethyl-8-nitro-4-oxyoctahydroindolizidine-5-ol 12:284,285 10,13-Dimethyl-9-tetradecen- 1-ol 26:66 hydrogenation of 26:66 10,13-Dimethyl-9-tetradecen-l-ol 26:66 Dimethylacetamide dimethylacetal 14:722-724 3,3-Dimethylallyl alcohol 7:100
3,3-Dimethylallyl bromide 8:70 Dimethylallyl diphosphate 7:323,324,330,348,352 Dimethylallyl pyrophosphate 22:255 4-(y,T-Dimethylallyl) tryptophan synthase 11:200 3-(1,1-Dimethylallyl) xanthyletin 4:374,375,399,400 synthesis of 4:374,375,399,400 1-(3,3-Dimethylallyl)-2hydroxynaphthalene 4:394 6-(3,3-Dimethylallyl)-7hydroxycoumarin 4:385,386 3 '-(T,T-dimethylallyl)-kievitone 28:228 biological activity of 28:228 8-(T,T-dimethylallyl)-wighteone 28:228 biological activity of 28:228 3-c~,c~-Dimethylallyl-4-hydroxy-6methoxy benzaldehyde 21:741 3,3-Dimethylallyldilaurylsulfonium perchlorate 8:40 Dimethylallylindole 2:447 Dimethylallylkaemp feride 26:802 8-y,y-Dimethylallylwighteone 25:541 Dimethylaluminium benzenethiolate 14:755 Dimethylaluminium complex 14:750 Dimethylaluminium tert-butyl sulphide 1:271,272 Dimethylaluminum amide 1:288 Dimethylamino pyridine 21:739 D4-(imethylamino) pyridine 12:328,473 2-Dimethylamino- 1,2-dihydroacronycine 20:800 2-Dimethylamino-5-methoxy-benzoquinone 13:434 (9R)-Dimethylamino-9-deoxyerythromycin A 13:181 Dimethylaminocinnamaldehyde 21:542, 546,550 Dimethylaminocinnanaldehyde assay 21:511,521 4-Dimethylaminopyridine (DMAP) 11:154;24:24,25 a-Dimethylation 6:8 in (+)-brasilenol synthesis 6:8 7-12-Dimethylben[a] anthracene (DMBA) 10:4;25:937;20:508;25:44
270 Dimethylbenz[a]anthracene 21:7,12,705 7,12-Dimethylbenzanthracene (DMBA) 21:744;30:762 effect on skin papillomas 30:762 4,5-Dimethylbenzo [b] furan 5:277,278 7,12-Dimethylbenzyl [a] anthracene (DMBA) 24:217 N,N-Dimethylbenzylamine 5:827,828 endo-7,7-Dimethylbicyclo-[3.3.1 ]nonane-3-ol-9-one 15:135 Dimethylchlorosulfonium chloride 9:526 4,4-Dimethylcholestane 25:56 4,4,-Dimethylcholestane-3 a,5 a-diol 25:56 2,2-Dimethylchromans 13:367 Dimethylcopper lithium 1:263 Dimethylcrocetin 26:303 4,4-Dimethylcyclopentene 13:36 4,4-Dimethylcyclopentenone 13:9,14 5,9-D imethyl-dec a-2,4,8-trienoate 20:839 2,5-Dimethyl-E- styryl-pyrazines 5:225 3,7-Dimethylet- 6- ene- 1,2,3 ,-triol 25:134 N,N-Dimethylethanolamine 5:229 Dimethylformamide 21:597 Dimethylformylpyrazine 5:240,241 2,5-Dimethylfuran 27:850 (+)-Dimethylisoariciesinol-2-a-xylose 26:195 ot,cx-Dimethylisobutyric acid 21:224 (3R,4S)-N, O-Dimethylisostatine 12:477 3,7-Dimethyl-l,6-octadien-3-ol 25:140 3,7-Dimethyl-l-octene-3,8-diol 25:138 (-)-Dimethylmatairesinol 18:558 (3Z)-4,8-Dimethylnon-3-en- 1-yl sodium sulfate 28:721 as sulfated alkene 28:721 N, O-Dimethylnorbelladine 20:359 from Pancratium maritimum 20:359 ( 1'E, 5'E)-2-(2', 6'-Dimethylocta- 1', 5', 7'trienyl)-4-furoic acid 29:91 activity in PLA assay system 29:91 ( 1'E, 5'Z)-2-(2', 6'-Dimethylocta- 1', 5',7'trienyl)-4-furoic acid 29:91
activity in PLA assay system 29:91 2E-6E-2,6-D imethylocta-2,6,-diene-1,8diol 25:138 2E-6Z- 2,6-D imethylo cta-2,6,-die ne-1,8diol 25:138 7,11-Dimethyloleoside 26:334,343 4,4-Dimethyloxazolidin-2-thione derivative 12:164,166 (2R,3R)/(2S,3S)-2,3-Dimethylpentane1,2-diol-enantiomeric pair 15:86 Dimethylphenylethylpyrazine 5:241 ( 1S,R)- 1-Dimethylphosphinyl-2,3- Oisopropylidene-D-glycerols 6:353,355 3- ~-cx-Dimethylpropyl-4,6dimethoxybenzoic acid 21:741 2,5-Dimethylpyrazines 5:222,228,233, 237 2,6-Dimethylpyridine 6:424-426 5,5-Dimethyl-pyrroline-N-oxide 22:316 Dimethylsodium 4:322,323 4,4,-Dimethylsterols 25:56 (+)-(R)-3,3-Dimethylsulfonio-2methoxy-pyropanoate 25:846 5-Dimethylsulfonio-2-methoxypropanoate 25:846 3-Dimethylsulfoniumpropionate(DMSP) 25:846 Dimethylsulfoxonum methylide 6:550, 551 Dimethylsulphoxide 21:597;27:512 CH3SOCH2 from 27:512 10,13-Dimethyltetradecanoic acid 26:65-67 total synthesis of 26:67 9,13-Dimethyltetradecanoic acid 26:65,66 total synthesis of 26:66 2,2'-N, N-D imethyltetrandinium dichloride (bisbenzylisoquinoline) 29:578 effects on ACE 29:578 3-(4,5-Dimethylthiazol-2-yl)-2,5diphenyltetrazolium bromide method (MTT) method 25:266 Dimethyltryptamine 2:395 N,N-Dimethyltryptamine 21:68,84 1,3-Dimethyluric acid 22:6
271 1,7-Dimethylxanthine 22:5,6 2,5- Dime thyl-Z- 3- styryl-p yrazine s 5:225,239-241,257,262 Dimethyl-j%propiothein 25:846 2,6-Dimethyoxy-l,4-benzoquinone 23:537 5,8-Dimethyoxyisocoumarin 7:227,228 from Artemisia carvifolia 7:206 from soyasaponin I 7:227,228 3,5'-di-O-methyl-myricetin 7:227 3',4'-Dimetoxyflavone 5:653 Diminazene (berenil) 26:786 Dimnoline B 25:818 Dimoracin 20:282 Dimorphecolic acid 1:533,534 synthesis of 1:533,534 Dimsyl sodium 6:482,492,493 Di-myristoylphosphatidylcholine (DMPC) 18:839 2,4-Dinitro-phenylhydrazone 8:43,319 bis-Dinitrophenylhydrazone derivative 15:228 of myoporone 15:228 Dinklageine 15:228 from Strychnos dinklagei 6:522 spectral data of 15:228 synthesis of 6:526 Dinocophylline B&C 26:822,823 Dinoflagellates 17:20;21:300,301; 23:178,185;27:875;30:521 Dinophyceae 6:134,135 Dinophysis 21:301;27:875 Dinophysis acuminata 5:384 Dinophysis fortii 17:20;25:729 Dinophysistoxin-1 17:19,269 Dinophysistoxin-2 17:20 Dinophysistoxin-3 17:19 Dinoponera grandis 5:223,224,229,254 Dinorcholenic acid 16:323 Dinor-sesquiterpenes 9:65 26,27-Dinortyphasterol 16:352 Dinosterol 9:47;23:169 Dinoxanthin 23:179 1,6-Di-O-3-Nitropropanoyl-13-Dglucopyransoide 27:522 3,4-Di- O-acetyl- 1,2:5,6-di- Ocyclohexylidene-myoinositol 18:426
2,3-Di-O-acetyl- 1,6-anhydro-3-Otrifluoromethylsulfonyl- f3-Dgalactopyranoside 8:331,341 Di-O-acetyl-2,3-dideoxy-[3-D-threo-hex2, 1-(4,6-enopyranosyl) uracil 4:236,237 synthesis of 4:236,237 4,6-Di-O-acetyl-3-deoxy-D-glucal 14:146 3,4-Di- O-acetyl-6- O-trityl- 1,2cyanoethylidene-a-D-galactose 14:241 3,4-Di- O-acetyl-6- O-trityl- 1,2-Ocyanoethylidene-13-D-manno se 14:240,246 (+)-2',4'-Di-O-acetyl-7,8-dihydronogarene 14:67,68
(+)-2',4'-Di-O-acetyl-7,9-di-epi-7-con-
O-methylnogarol 14:75 (+)-2',4'-Di-O-acetyl-7-con-Omethylnogarol 14:75 (+)-2',4'-Di-O-acetyl-7-methoxynogarene 14:80 (+)-2',4'Di-O-acetyl-9-benzyloxy-9demethyl-9-methoxynogarene 14:82(+)-2',4'-Di-O-acetyl-9-demethyl-7,9dimethoxy-nogarene 14:82 (+)-2',4'-Di-O-acetyl-9-demethyl-7methoxynogarene 14:80 (-)-2',4'-Di-O-acetyl-9-demethyl-9hydroxy-7-methoxynogarene 14:82
(+)-2',4'-Di-O-acetyl-9-epi-7-
deoxynogarol 14:71 2',4'-Di-O-acetyl-con-nogarol 14:74 3,6-Di-O-acyl-4-deoxy-[3-D-glycerohex-3-enopyranosyl-2-ulose 10:353 3,4-Di-O-benzoyl-2-O-trityl-a-Lrhamnopyranoside 14:242 6,7-Di-O-benzoylcastonospermine hydrochloride 12:345 1,4-Di-O-benzoyl-myo-inositol 18:421 4,6- Di- O-b enzylide ne- 2,3- O-p arato luenesulfonyl-c~-D- glucopyranoside 14:154 4,6:4 ',6'-D i- O-benzylidene-~-c~'trehalose 14:149
272
1,6-Di-O-benzyl-N-acetyl-muramic acid methyl ester 6:388,389 1,3-Di-O-caffeoylquinic acid 25:920 3,4-Di-O-caffeoylquinic acid 25:920 3,5-Di-O-caffeoylquinic acid 25:920; 27:418 3,6-Di-O-caffeoylquinic acid (3,5DCQA) 25:938 4,5-Di-O-caffeoylquinic acid (AQAs) 25:920,938,939;27:418 Di-O-caffeoylquinic acids 25:921,947, 948 Dioclea glabra (Dioclea leiophylla) 29:598 1,2:3,4- Di- O-c yclohex ylidene-myoinositol 18:428 ent-3fl-6fl-Dihydroxy- 13-manoyl oxide 25:261 Di-O-hemiphthalates of olean- 12- ene-3 fl,30-diol (deoxyglycyrrhetol) 25:58 3:5,9:11-Di-O-isoproplidene derivative 6:264,265 Di-O-isopropylidene-cx-D-glucofuranose 1,2:5,6;6:282,283 1,2: 5-Di-O-isopropylidene-Dglucofuranose 14:159 Di-O-isopropylidene-(+)-valienamine 10:507 4,7: 5,6-Di- O-isopropylidene-( 1,4,6/5)4,5,6-trihydroxy- 3-hydro xymethyl- 2cyclohexenylamine 10:511,512 1,2:5,6-Di- O-is opropylidene- 3- O-ptoluenesulfonyl- D- glucofuranose 14:171 1,2:5,6-Di- O-isopropylidene-3- Otrifluoro-methyl-sulfonyl-cx-Dallofuranose 8:329 1,2:3,4-Di-O-isopropylidene-6-O-ptolylsulfonyl-cx-D-galactopyranose 8:339,340 1,2:5,6-D i- O-isopropylidene-Dglucofuranose 14:168 1,2:4,6-Di- O-is opropylidene-Dhexofuranose 14:160 from D-allose 14:160 from D-altrose 14:160 from D-galactose 14:160
from D-glucose 14:160 from D-gulose 14:160 from D-idose 14:160 from D-mannose 14:160 from D-talose 14:160 Di-O-isopropylideneglucofuranose 14:157 S-methyl dithiocarbonate 14:157 1,2:3,4-Di-O-isopropylidene-cx-Dgalactopyrano se 10:476 1,2:5,6-Di-O-isopropyli dene-cx-Dglucofuranose 14:152 2,3: 5,6-Di-O-isopropylidene-cx-Dmannofuranosidel0:541 2,3:4,5-Di-O-isopropylidene- f3-Dfructopyranose 12:350 (+)- 1-deoxy-6-8a-Di-epicastanospermine from 12:350 (-)- 1-deoxy-epi-castanospermine from 12:350 1,3-Diol monotosylate 3:73 vic-Diols 2:173 22,24-Di-O-methyl soya-sapogenol B 7:157,158 from soyasaponin I 7:157,158 3-O-Di-O-methyl xylose 7:298 2,4-Di- O-methyl- [3-D-quinovopyranosyl-( 1>>2)-5-O- sulphate-f3D-fucofuranosyl 15:66 from Dermasterias imbricata 15:66 ent-8,9-Di-sclareol 25:252 ent-8,9-Di-epi-sclareol 25:252 Dioncopeltine A 26:822,823 antiplasmodial activity of 26:822,823 Dioncopeltine B 26:822,823 antiplasmodial activity of 26:822,823 Dioncophyllaceae 20:407-409,417 Dioncophylline 20:265 Dioncophylline A and C 20:408, 418,437,438,440 DIOP 13:72 2,6-Di-O-penthyl-3-O-trifluoroacetyl 27:368 Dioscin 21:636
273
Dioscorea batatas 23:342 Dioscorea collettii var. Hypoglauca 21:636 Dioscoreajaponica 21:584 Dioscoreophyllum cumminsii 27:19 monellin from 27:19 Diosgenin 2:443,444;7:19;23:573,821 Diosma crenulata 29:579 Diosmetin 20:712;22:328;25:618; 26:746,756;27:844 from Salvia candidissima 20:712 Diosmetin (5,7, 3'-trihydroxy-4'methoxyflavone) 29:577 effects on aminopeptidase N 29:577 Diosmin (3', 5,7-trihydroxy-4'-methoxy7-O-rutoside) 29:579 effects on ACE 29:579 Diosmin 23:747;26:752,755-757,759, 766 Diospyrin 26:804 Diospyros 7:406,423 Diospyros abssinica 7:417 Diospyros canaiculata 2:224 Diospyros kaki Thunb 19:246;21:498; 29:588 Diospyros leucomelas 22:105,119,125 Diospyros montana (Ebeaceae) 2:231,754;26:804 Diospyros perigrina 29:578 Diospyros usmabarensis F. 7:427, 435;22:520 for epilepsy 22:520 Diospyros zombensis 7:417,427,429 2,9-Dioxabicyclo [3.3.1] nonane 14:108 2,7-Dioxabicylo [4,3.o] honane 25:803 Dioxacyclohexenone 1:642 Dioxanone 12:15,16 Dioxapyrrolomycin 25:757,794;26:488 1,6-Dioxaspiri[4,4]nonane 19:128 (R/S) 1,6-Dioxaspiro [4.5] decane 14:523,524 asymmetric synthesis of 14:523,524 (R/S) 1,7-Dioxaspiro [5.5]-undecane 14:521-526 asymmetric synthesis of 14:521526 from Dacus oleae 14:521
from (S)-malic acid 14:521,522 from (-)-menthyl (S)-p-toluene sulfinate 14:522,523 Dioxepane 10:218,219 synthesis of 10:218,219 Dioxepinooxindole ring system 28:360 construction of 28:360 Dioxin 26:756 antagonist effect of 26:756 2H,4H, 1,3-Dioxin derivative 12:160,161 1,3-Dioxo-7c~, 11[3H-2,3-secogermacra4Z,9Z-dien- 12,6cz-olide 27:573 Dioxoabieta-8,13-diene 20:670,11,12 3,5-Dioxoalkanoates 11:114 Dioxoaporphines 20:480 (Z)- 1,4-Dioxodec-7-ene 19:161 Dioxoester 11:117 1,1,-Dioxo-l,4-thiazine ring 25:861 1,3-Dioxolan-4-ones 1:603,609 1,3-Dioxolanes 1:584 Dioxolanes 1:644 Dioxopiperazenes 24:1034-1040,1080 10,17-Dioxosparteine skeleton 27:272 9~, 13c~-epi dioxyabiet-8( 14)-en- 18-oic acid 29:99 activity in EBV assay system 29:99 Dioxygenases 9:559 3,4-Dioxygenated flavones 30:240 3,2'-Dioxygenated flavonoids 5:673694 Dioxygenation 9:560,561,566,567, 570,573,575 R-Dioxygenation 9:574,575 Di-palmitoylphosphatidylcholine (DPPC) 18:839 5,5'-Dipentacene 14,14' (5H,5'H)-dione 11:126 Dipeptide 26:1224 Panek's synthesis of 26:1224 Dipetallolema viteae 26:487 Diphenol-oxygen oxide reductase 25:654 Diphenols 17:368 o-Diphenols 25:654,670 Diphenyl phosphane chloride 9:524 Diphenyl phosphorazidate (DPPA) 4:83
274
2,2-Diphenyl- 1-picrylhydrozyl (DPPH) 23:769 1,1-Diphenyl-2-picryl-hydrazyl (DPPH) 22:318;23:534;25:934,948 (S, S)- 1,2-Diphenylethane- 1,2-diol 11:423,424 1,7-Diphenylhept-4-en-3-one 23:803 Diphenylphosphoryl azide 10:289,290, 641,644,645,652,656,657 1,2-Diphenylpropane derivatives 27:894 Diphosgene 12:113 Diphospha adamantane 9:528 1,3-Diphospha-heterocycles 9:529 Diphyilin asioside 26:226 Diphylleia 26:172 Diphylleia cymosa 5:492 Diphyllin 5:461,462,493 ;26:226 Diphyllin acetate 26:194 Diphyllin acetyl apioside 26:263 Diphyllin apioside-5-acetatc 26:226 Diphyllin natural products 26:166 Diphyllinin 26:194 Diphyllinin crotonate 26:194 Diphyllinin monoacetate 26:194 Diphyllin-O-apioside 26:194 Diphyllin-O-apioside-5-acetate 26:194 Dipiperidine 21:107 Dipiperidine spiroalkaloids 14:748 biosynthesis of 14:748 hypothetical 14:748 Dipiperidine-[~-carbolines 14:759-765 Dipladenia martiana 29:578 Diplamine 10:244;25:820,821,893 Diplococcus ganera 29:311 Diplodia gossypina 25:162,166,168,170 Diplodia maydis 4:600 Diplodiatoxine 4:600-602 biomimetic synthesis of 4:620 synthesis of 4:600-602 Diplodiosis 4:600 Diplophyllin 2:278,279 Ent-Diplophyllolide 2:278,279 Diplophyllum albicans 2:278;24."183 Diploptera punctata 22:376,382 Diplorhoptrum 6:422,423 Diplosoma sp. 25:821 ;28:636 diplamine from 28:636
Diplosoma virens 23:244;25:888; 28:644,645
Dipodascus sp. 12:337
Dipolar [3+2]cycloaddition 19:155 1,3-Dipolar addition 1:230,231,291 1,3-Dipolar cycloaddition 1:227,278, 284,285,324-344 ;4:435 ;10:65,66, 138,139,215,216,11:238-41,264,283 [3+2]-Dipolar cycloaddition 13:191,500 Dipolar cycloaddition 13:84-86;19:42 intramolecular 13:84-86;19:42 of methyl acrylate 19:309 of alkenes 16:463 of nitrile oxide 16:464 to 3-oxidopyrazinium 10:135 Dipolar learsiae 25:788 Dipole LUMO control 1:363 Dipole moment 30:534 Diprenylated chalcones 29:773 antileishmanial activity of 29:774 Diprenylated flavanones 29:781 abyssinone III as 29:781 6,8-diprenyleriodictyol as 29:781 dorsmanine E as 29:781 dorspoinsettifolin as 29:781 epidorsmanin F as 29:782 7,8-[2"-(1-hydroxy-1methylethyl)-dihydrofurano]-6prenyl-5,3 ',4 '-trihydrox yflavone as 29:782 linklagin A as 29:781 lonchocarpols C derivatives as 29:782 6,8-Diprenylflavanone 4:378,380 from 7-hydroxy-flavanone 4:378,380 in azetidinone synthesis 4:437 6,8-Diprenylnoreugenin 4:382,384 6,8-Diprenylorobol 28:243 anti-Helicobacter pylori activity of 28:243 Diprian pini 27:384 Dipropyl disulfide (DPDS) 23:469 Dipropyl sulfide (DPS) 23:459,469,476 N,N-Diprotected 4:124 L-alaninals 4:124 Gt-amino aldehydes 4:124
275
Dipsacus afer 21:672 D-(+)-DIPT 19:445,480,490 D-(-)-DIPT 19:490 DIPT 4:172-174,179,186,187 Dipterocarpaceae 23:531-561 bioactive constituents of 23:531561 genera in 23:532 Dipterocarpaceae sp. 27:766 Dipterocarpus alatus 23:532 Dipteryx alata 29:598 Dipyranoside 21:432 Dipyrone 30:192 as analgesic/antipyretic 30:192 Dipyrromethane 9:592,593 Diquat 26:374 Diquinane 13:3-52 diterpenes 13:3-52 sesquiterpenes 13:3-52 sesterterpenes 13:3-52 synthesis of 13:3-52 Diradical trapping 3:20 Dirca occidentalis 26:219 genkwanin from 26:219 (+)-lariciresinol from 26:219 sitoindoside II from 26:219 Direct cis-hydroxylation 14:183 Direct-acting mutagen 30:174 daunorubicin as 30:174 methyl methanesulfonate as 30:174 Directed hydromagnesiation 10:29,30 Directed-aldol condensation 15:15 Dirhodium tetrakis (trifluoroacetate) 10:210 Diribonucleoside 2',3'-cyclic phosphates 14:285 Dirithromycin 13:171,172 Dirman 17:28 c~-l,4-Disacccharide 8:369,370 Disaccharide 6:377,29,33,50,53,60, 62,70;10:338;11:469 synthesis of 11:469 semi-synthesis of 17:636 Disaccharide acids 6:401,407,412,413 Disaccharide dipeptides 6:395,396, 398,406-409,41-416 anomeric characterisation of 6:413,416
anomeric deprotection of 6:413416 tert butyl ester of 6:413-415 2D COSY spectrum of 6:407,408 synthesis of 6:397,398,406,407 Disaccharide lactone 6:395,396,407 Disaccharide methyl ester 6:395,396 synthesis of 6:395,396 Disaccharide thioether 8:342 Disaccharide-L-alanyl-D-isoglutamine benzyl ester 6:410,411 C-Disaccharides 3:223,224 synthesis of 3:223,224 c~-Disaccharides 30:459 yield of 30:459 1,2-Disaccharides 8:362 synthesis of 8:362 Discadenine 9:220 Disc-diffusion method 20:712 Discobahamin A 23:341 Discobahamin B 23:341 Discobahamins A&B 26:1202 Discodermia 25:867;26:1175;28:138, 679 antifungal activity of 28:139 cytotoxic activity of 28:139,679 deepwater species of 28:679 polydiscamide A from 28:679 Discodermia calyx 5:396;25:731; 26:1204;27:877;28:713 Discodermia dissoluta 21:411 ;26:1205 discodermide from 21:411 Discodermia kiiensis 26:1201,1204 Discodermia polydiscus 25:763 Discodermia sp. 21:252;26:1201,1202 calyculins E,F from 21:252 Discodermide 26:1206 Discodermin-halicylindramide 25:864 Discodermins A-D 26:1201,1202 Discodermins E-H 26:1201,3202 Discodermis A-H 25:665,865 Discodermolide 26:1205,1206,1243, 1245-1248;30:3,4,5,6,10-12, 13-19,17,19-21,22-26 against human lung carcinoma cell 30:5 as antitumor agent 30:3 as immunosuppressive agent
276
30:3 as microtubule stabilizing agent 30:5 biological activity of 30:4 crystal X-ray crystallography of 30:4 inhibition of host-splenomegaly response 30:4 1D/2D NMR spectra of 30:4 isolation of 30:4 Marshall's synthesis of 30:19-22 Myles' s synthesis of 30:10-12 olefinic linkages of 30:13 Paterson's synthesis of 30:22-26 Schreiber's synthesis of 30:6-10 reverse-phase chromatography of 30:4 silica gel chromatography of 30:4 Smith's synthesis of 30:13-19 suppression of two-way mixedlymphocyte reaction 30:4 structure elucidation of 30:4 structure of 30:3 synthetic routes of 30:3 total synthesis of 30:5,13 Discokiolide A-C 26:1203 Discorhabdin 25:824 Discorhabdin A 25:760,761,822 Discorhabdin alkaloids 25:708 Discorhabdin B 21:311 ;25:760, 761,822,823 Discorhabdin C 25:760,776 Discorhabdin D 25:822,823 Discorhabdin P 25:760,761 Discorhabdin Q 25:760,761,822,823 Discorhabdins 21:311 ;25:823 Discorhaines 25:707 Discovery 30:799 of natural opioid peptides 30:799 Discriminative functionalization 10:415 in hexopyranoses 10:415 of geminal dimethyl groups 10:415 Diseases 30:70 arteriosclerosis 30:70 asthma 30:70 atopic dermatitis 30:70 hyperlipidemia 30:70
Disiamyl borane (bis(3-methyl-2-butyl) borane 14:183 Disiamylborane 4:116,117 Dismosin 25:469 Disodium salt of phosphocombretastatin A-4 24:406 angiogenesis inhibitory activity of 24:406 anti-tumor vascular inhibition of 24:406 7-Dis-O-methylnogarol 14:78 (+)-Disparlure 16:695-696;19:481 synthesis of 16:695-696 Dispermol 23:682 Dispermone 23:682 Dispermoquinone 23:709;30:672 ~H NMR spectrum of 30:672 molecular formula of 30:672 structure of 30:673 Dispsacus saponin C 30:204 antinociceptive effects of 30:204 Dispuupehedione 25:715 Dissymmetrization 19:45 enzymatic 19:45 of meso compound 19:45 Distamycin 5:551,552 Distamycin analogues 5:558-564,567 synthesis of 5:558-564,567 Distamycins (pyrrole amidines) 24:546 antiviral microbial-derived compound 24:546 Distemonanthus benthamianus 5:676681 Distichol 23:533,535;26:1562 Distillation solvent extraction 21:575 Distolasteria nipon 7:299;15:55 Distortionless enhancement by polarization transfer (DEPT) 30:587 of (-)-hemone 30:587 Distratamide A 25:881,882 Distratamide B 25:881,882 Distratamide C 25:881,882 Distratamide D 25:881,882 Distyophaeria sericea 25:722 Distyostelium 25:526 Distyota ciliolata 25:722 1,3-Disubsituted tetrahydro fl-carboline 25:16,17
277 c&, 2,5-Disubstituted 2,5dihydrothiophene- 1,1-dioxides 21:387 ~,c~'-Disubstituted 3-piperidinol alkaloids 29:420 absolute stereochemistry of 29:421 trans-selectivity of 29:423 stereochemical control of 29:422 stereoselectivity of 29:422 N,N-Disubstituted amides 4:389 2,5-Disubstituted ant pyrrolidines 6:441,442 synthesis of 6:441,442 Di-substituted azulenes 14:336-338 oxidation of 14:336-338 N,N-Disubstituted benzyl amines 4:389 in metallation reactions 4:389 cis-Disubstituted butyrolactones 24:751,753 by Stobbe condensation 24:751 2,5-Disubstituted decahydroquinoline 19:3-13 3,5-Disubstituted indolizidines 11:245 absolute configuration of 11:245 from dendrobatid flogs 11:245 synthesis of 11:245-259 5,8-Disubstituted indolizidines 11:260267 via hetero Diels-Alder approach 11:260-267 synthesis of 11:260-267 3,5-Disubstituted indolizidines 19:24-37 ;27:236,240 conformers of 27:237 FTIR spectral analyses of 27:241 3-hexyl-5-methylindolizidines 27:241 (-)-myrmicarin 237A as 27:240 (+)-myrmicarin 237B as 27:240 structure identification of 27:240 synthesis of 19:24-37 5,8-Disubstituted indolizidines 19:3851;27:235,238 conformers of 27:237 mass fragmentation pathway of 27:238 synthesis of 19:38-51 cis-2,8-Disubstituted oxocane 10:232
2,8-Disubstituted oxocene 10:223 synthesis of 10:223 cis-2,5-Disubstituted piperidine 19:36 cis-ct, cx'-Disubstituted piperidines 14:571-574 synthesis of 14:571-574 2,6-Disubstituted piperidines 6:430,431 cis-~, ~'-Disubstituted pyrolidine 14:571-574 synthesis of 14:571-574 cis-2,5-Disubstituted pyrrolidine 11:241,242 by ozonolysis 11:241,242 (+)-monomorine I from 11:241,242 2,3-Disubstituted quinolines 3:393,394,396 synthesis of 3:393,394,396 2,4-Disubstituted quinolines 3:394,396 synthesis of 3:394,396 1,4-Disubstituted quinolizidine 27:235,238,244 mass fragmentation pathway of 27:238 NMR characterization of 27:244 qulnolizidine 217A 27:244 quinolizidine 231A 27:245 quinolizidine 233A 27:245 quinolizidine 207I 27:245 quinolizidine 235E 27:245 quinolizidine 275A 27:246 3,5-Disubstituted-2-formylpyrrolidine 19:316 4,5-Disubstituted-2-oxazo lidinone 12:427,428 from 4-methoxy-2-oxazolidinone 12:427 N,N'-Disuccinimidylcarbonate 21:165 Disulfide bond 2:28,30 Disulfide-containing peptides 2:36 Diterpene 30:748 Diterpene acid 27:13,23 from pine tree 27:13 structure of 27:23 Diterpene alcohol 5:3,31-37 Diterpene derivatives 30:706 Diterpene dibenzoates 20:475 of Caesalpinia pulcherrima 20:475
278 Diterpene isothiocyanates 25:853 Diterpene lactone 30:739 structure of 30:739 Diterpene synthetase (cyclase) 7:109,110 Diterpenes 2:402,403,404;5:3,3137;6:110,7:102,121,122,187189;15:252-260;17:8,11-15,27,148; 18:756 ;21:234 ;22:379;23:488,682; 24:196-202,284,799;27:830 reduction of 27:830 synthesis of 24:197-202 Diterpenes, bioactive 29:169 carnosic acid as 29:169 miltirone as 29:169 pisiferic acid as 29:169 stereoselective synthesis of 29:169 triptolide as 29:169 synthesis of 29:169 Diterpenoid alkaloid 25:534 aconifine 25:534 ajacine 25:534 avadharidine 25:528 bikhaconitine 25:534 cassaidine 25:535 cassaine 25:535 condephine 25:528 delcoline 25:528 delcorine 25:528 delphinine 25:534 falaconitine 25:534 indaconitine 25:534 Jesaconitine 25:534 lappaconitine 25:534 mesaconitine 25:534 N-deacetyllappaconitine 25:534 pseudoconitine 25:534 raynodine 25:535 Diterpenoids 9:78,265,272,283,293, 295,297,298,639-642; 14:63964;15:111-185;20:660;23:799; 27:857;30:707 biological activity of 30:707 from 2E, 5E, l OE-geranylgeranyl pyrophosphate 30:707 Diterpenoids (Di) 29:98 2,6-Di-tert-butyl-4-methylphenol 9:579 Dithaiothreitol 4:101
1,3-Dithialane system 1:537 synthesis of 1:537 1,3-Dithiane 6:307-309,332,338 Dithiane-epoxide coupling 30:14 1,3-Dithianyl derivative 30:434 acylation of 30:434 2-(1,3-Dithianyl)-lithium 30:458 1,2-Dithietane 10:229 synthesis of 10:229 Dithiins dipsaci 26:437 Dithioacetal 11:357;30:439,458 transformation of 30:439 ylides gene from 30:458 Dithioacetal S,S-dioxides 6:307-349 Dithioacetal S-oxides 6:307-349 Dithiocarbonates 1:452-453;26:1091, 1092 antimicrobial activity of 26:1091,1092 1,4-Dithiocello-thiocellobioside 8:348,349 1,4-Dithiodisaccharide 8:348,349 Dithioerythritol (DTE) 2:20 Dithiofurodysinin disulfate 25:815 4,4'-Dithiomaltotrioside 8:331 Dithiomethyl lissoclinotoxin C 25:833 Dithiothreitol 2:20,579;25:836 1,4-Dithio-D-cellobiose 8:347,349 Di-trans-polycis-ct-saturated prenols (dolichols) 8:66 Di-trans-polyscis-prenols 8:66 Dittrichia viscosa 22:428;25:613 quercetin from 22:428 3-O-methylquercetin from 22:428 7-O-methylaromadendrine from 22:428 Ditylenchus destructor 26:460 Ditylenchus dipsaci 26:493 Diuranthera major 21:675 diuranthoside B from 21:675 Diuretic 23:499 Bacopa monnira as 23:499 Diuretic activity 12:398;17:451;28:200 of genus Morus 28:200 Diuretic agent 23:642 of Teucrium sp. 23:642 (-)-3,4- Divanillyltetrahydrofuran 26:191
279 Divarine 26:1056 Diveprisine 2:125 Divergent synthesis 12:330 Diversifolin 29:89 activity in NFkB assay system 29:89 Diversifolin methyl ether 29:89 activity in NFkB assay system 29:89 Diversity-oriented synthesis 29:452, 463 ofaminocarbafuranoses 29:463 of carbafuranoses 29:452 Divinyl cyclopropane rearrangement 12:246,247 cis- 1,2-Divinylcyclobutanols 11:45,47 D ivinylc yc loprop ane-c y c loheptadiene conversion 3:287 Divinylketone 8:412 Diydronaphthalene 8:402,403 synthesis of 8:402,403 L-Djenkolic acid 26:481 Di dopamine receptor 25:529 DL-3-( 3,4-Dihydroxyphenyl) alanine 6:312 synthesis of 6:312 DL-Dopa (DL-3-(3,4-dihydroxyphenyl) alanine) 6:312 synthesis of 6:312 DL-epiisopodophyllotoxin 18:600 DL-myo-inositol 1,3,4,5tetrakisphosphate 18:413 D-lyxo-hexulosonic acid 30:419 DMACA assay 21:511,522,524,525 DMACA protocols 21:522,523 DMACA reagent 21:522,523 D-manno epimer 30:433 oxalacetic acid 30:433 D-mannono-nitriles 10:463 catalytic hemihydrogenation of 10:463 Nefreaction of 10:464 D-manno-octulosonic acid (KDO) 30:434 stereoselective synthesis of 30:434 D-mannosamine 30:452 D-mannose 30:433 reaction of 30:433
DMAP (4-dimethylaminopyridine) 11:154,157;21:739 DMAPP 7:98,110,11:201,202,19:520 DMAT synthase 11:202 DMBA 21:744;25:45,48,61,62,65 DMBA/TPA induced skin tumor 25:48 inhibition of 25:48 DMBA-TPA 21:642,643,645 DM-CCK sonication 18:844 DMDP (2,5-dihydroxymethyl-3,4dihydroxy-pyrrolidines) 7:13,14 DMSO 6:310,329,330 (Dmtl, Tic2)DYN-A-(1-11)-NH2 30:809 activity in functional bioassay 30:809 743-DNA 25:826 DNA 7:9 DNA complex 5:575-581 DNA polymerase 21:96;25:895 DNA polymerase activity 23:218 DNA polymerase B 25:871 DNA polymerase inhibitors 25:868 DNA synthesis 30:61,67 (R)-8-DNA synthesiser 19:539 DNA topoisomerase 21:96 DNA topoisomerase I inhibitors 28:621 ceramide 1-sulfates as 28:621 DNA viruses 30:395 DNA-damaging activity 20:467 DNA-damaging agents 20:460,20:461 DNA-damaging antitumor activity 25:796 DNA-damaging natural products 20:457-500 coumarin as 23:335,356,357, 393,550,553 18,19-dihydrousambarine as 26:1062 5', 6'-dihydrousambarensine as 26:1062 ecteinascidins as 23:253,255 flavopiridol as 21:135,136 magainin-2 as 27:807 strychnopentamine as 26:1062 strychnos bisindole as 26:1062 usambarensine as 26:1062 usambarine as 26:1062 vinblastine as 14:805 vincristine as 14:805
280
(Ac-D-Nal(2)-D-Phe(4CL)2-Pal(3)3-DCit6,D-Alal0) 27:795 DNA-methyl green assay 30:733 DNA-scission 30:164 by alkylresorcinol 30:164 DNA-virus 30:394 hepatitis B type of 30:394 D-NMR 21:584,1992 3-(2',3'-Doacetoxy-2'-methyl-butyryl) cauhtemone 7:141 Docosahexaenoic acid 28:565 in fish oils 28:565 y-Dodec-(6Z)-enolide 13:315 3Z,6Z,9Z-Dodeca-3,6,9-trienoic acid 21:306 Dodecahydro benz[f]indolo [2,3,-a] quinolizidine 25:20 Dodecanol 22:663 4-Dodecanolide 1:683,684 synthesis of 1:683,684 y-Dodecanolides 13:314 Dodecanoylphloroglucinol 5:753,754 Dodecapentaenedioic acid 21:408 Dodecatetraeneamide 21:385 6-Dodecynoic acid methyl ester 2:17 Dodonaea glabra 24:151,152 dodonosides A from 24:151,152 dodonosides B from 24:151,152 Dodonaea saponins 15:191;21:657 Dodonaea viscosa 7:139,427;25:276 Doebher-von Miller quinoline synthesis 1:171 Dolabelides A 19:557 Dolabella 25:724 Dolabella auricularia 4:87,420,421; 19:557,601 ;25:716,760,763,878, 887;28:648,649 sequence of 28:648 Dolabellane 25:690,790,791,888 Dolabrane akendo 1 29:100 activity in TPA bioassay system 29:100 [3-Dolabrin (tropolone monoterpene) 1:527;29:583 effects on carboxypeptidase A collagenase 29:583 synthesis of 1:527
Dolaisoleucine 12:477,483-486 synthesis of 12:477,483-486 Dolasta-1 (15),7,9-trien-14-ol 6:52 by intermolecular [2+ 1] cycloaddition 6:52 by intermolecular reductive coupling 6:52 by three-carbon annulation 6:52 from Dictyota divaricata 6:52 from Dictyota linearis 6:52 synthesis of 6:52 (+)-Dolasta-1 (15),8-dien-1413-ol 6:54 stereoselective synthesis of 6:54 Dolastane 6:52,54,79,182 Dolastatin 5:421 ;12:10,477,485,486; 12:10,477,485,486;5:421 ;25:10,716, 802,886,887 Dolastatin 10 28:145,649 antiproliferative activity of 28:145 as antineoplastic agent 28:649 Dolastatin 15 28:145 antiproliferative activity of 28:145 Dolastatin 3 28:648;4:87-89 as antineoplastic agent 28:648 synthesis of 4:87-89 Dolastatin F 25:887 Dolastatin I 25~87 Dolastatin-15 2/:806,804 Dolichodenis clarkii 5:224,253 Dolichol 22:253 Dolicholide 19:258 synthesis of 19:258 Dolichos biflorus 29:598 Dolichos kilimandscharicus 7:432,433 Dolichos lablab L. 19:247 Dolichos marginata ssp. erecta 7:413,414 Dolichyl [[3-33p] diphosphate 8" 107 Dolichyl phosphates 8:73,106 Domesticine 3:428 synthesis of 3:428 Domoic acid 1"/:21;21:70,302;26:479 DOPA 21:323;23:241 l-Dopa 21:587 Dopamine 18:53 ;21:10,18,50,57,68,84, 91,95,101,104 ;22:5,18,308,669,671,
281
673 ;24:55 ;25:516,530,535,536,538, 662 Dopamine D1 receptors 21:101;25:531 Dopamine D2 receptors 21:101;25:530, 532 type of G-protein-linked receptor 25:530 Dopamine receptors 21:95;22:22; 25:531 Dopamine signalling 25:531 Dopaminergic receptors 21:68 Dorestenia sp. 29:780 Dorimidazole A 17:18 Doris verrucosa 25:829;28:651 9-( 5-deoxy-5-methylthio- ~-Dxylo furanosyl)adenine from 28:651 digestive glands of 28:651 Dorstenia 29:793 Dorstenia barnimiana 29:795 Dorstenia barteri 29:777 Dorstenia brasiliensis 29:795 anticancer activities of 29:797 antileukodermic activities of 29:797 antimutagenic activities of 29:797 anti-tumor activities of 29:797 artemicide activities of 29:797 bacteriophagicide activities of 29:797 cytotoxic activities of 29:797 hepatoprotective activities of 29:797 radical-scavenging activities of 29:797 uses of 29:798 viricide activities of 29:797 Dorstenia bryioniaefolia 29:795 Dorstenia ciliata 29:772 Dorstenia contrajerva 29:763 Dorstenia dinklagei 29:787 Dorstenia drakena 29:763 Dorstenia elliptica 29:763 Dorstenia excentrica 29:763 Dorstenia gigas 29:763,767 Dorstenia kameruniana 29:783 Dorstenia lindeniana 29:763 Dorstenia mannii 29:781,782
Dorstenia poinsettifolia 29:795 Dorstenia proropens 29:774 Dorstenia psilurus 29:792 Dorstenia sp. 29:763 Dorstenia tayloriana 29:793 Dorstenia zenkeri 29:786 Dorylinae 6:421 Double cyclization reaction 10:121,122 Double dioxygenation 9:560,561 Double indolization 1:8,9 Double Michael addition 8:414,415 with extended acceptors 8:414, 415 with substituted ~,[3-unsaturated esters 8:412-414 with 2-trimethylsiloxycyclohexadienes 8:417 with c~,[3-unsaturated ketones 8:418 Double Michael reaction 3:143,144,735 Double-helical polynucleotides 23:120 Douglanin 7:232;27:551 Dounomycin 24:547 antiviral microbial-derived compound 24:547 Dowex 50(H § resin column 19:527 Dowex resin 22:285 Down-regulators (TNF-a) 25:465 PGE2 as 25:463 dexamethasone as 25:463 Doxorubicin 4:317-319;12:396,13:378, 379,14:3,21 ;21:136,157,174,177, 642;24:547 ;28:559,560,562;30:56 antiviral microbial-derived compound 24:547 as cancer chemotherapy drug 28:559;30:56 gastrointestinal toxicity by 28:562 immunotoxicity by 28:562 myelotoxicity by 28:562 Doxorubicin 14-O-~-D-galactoside 21:16t Doxorubicin 14-O-[~-D-glucuronide 21:161 Doxorubicin phosphate 21:160
282 Doxorubicin plus chitosan 28:560 tumor growth inhibition by 28:560 Doxorubicin-induced gastrointestinal toxicity 28:563 effects of chitosan 28:563 preventive effects of 28:563 12-Doxylstearate 30:170 mobility of 30:170 3-Doxysilychristin 26:255 as antihepatotoxic agent 26:255 DPDPE 30:817 analgesic activity of 30:817 DPY-4189 25:669 Dracaena loureiri 5:17;28:234 in apple juice 28:271 in cider 28:271 in pomace 28:271 nothofagin from 28:272 Dracaenones 5:19,20 APT spectrum of 5:19,20 biosynthesis of 5:20 ~3C-NMR spectrum of 5:20 CSCM 1D spectrum of 5:19,20 ~H-NMR spectrum of 5:17-20 INEPT spectrum of 5:19,20 synthesis spectrum of 5:20,21 Dracena mannii 21.'660 spiroconzole A from 21:660 Dracunculifosides 30:731 structure of 30:731 Dracunculin 7:225 Dragendorffs reagent 21:129,144 Dragmacidin 25:765 Dragmacidine D and E 25:798,799 Drechslera gigantea 6:555 Drechslera rostrata 26:227 Drechslera spp. 26:468 Dregamine 5:125 Dregaminol 5:125 Dregaminol methylether 5:127 Dreiding molecular models 30:196 Dreiding synthesis 6:45 DRH 30:448 synthesis of 30:448 D-ribo-2-heptulosonate 30:451 D-ribo-Deh ydrophytosphingosines 18:465 D-ribose 30:452
Driman-8,11-diol 1:663 synthesis of 1:663 Drimane 7:100,154,408;18:607;22:635, 636 Drimanic sesquiterpenes 6:108 Drimanolides 2:280 Drimartol A 7:224 Drimenin 4:407,408;20:469 (-)-Drimenin 6:14-15 Drimenin isomerisation 4:407,408 Drimenol 7:100,103,110,122,123 Drimenyl pyrophosphate 22:635,636 Drimys sp. 4:404 Drimys winteri Forst. 4:418 Drop method 22:493 Droplet counter current chromatography (DCCC) 24:137;25:205,206 Drosera capensis L. 26:115;830:345 cell suspensions of 30:345 Droserone 2:212-215,754,755 Drosophila 22:682;25:389;30:777 Drosophila melanogaster 18:698; 29:55;29:31 activity of alkaloids in 29:56 activity of ampelopsin B (distilbene) in 29:55 activity ofapiole in 29:56 activity ofbisphenol A in 29:56 activity of carnosiflosides in 29:55 activity of cis-resveratrol (monostilbene) in 29:55 activity of croweacin in 29:56 activity of cucurbitacins in 29:55 activity of deacetylpicracin in 29:55 activity of diethylphthalate in 29:56 activity of 2,3-dihydro-3[3methoxyichromolide in 29:55 activity of 2,3-dihydro-313methoxywithacnistine in 29:55 activity of 2,3-dihydro-3[3methoxy withaferin A in 29:55 activity of 23,24-dihydrocucurbitacin F in 29:55 activity of 2,6-dimethoxy-3,4methyl-enedioxy- 1-(2-
283
propenyl)-benzene in 29:56 activity of ecdysteroiods in 29:55 activity of 24-hydroxycarthamo sterone in 29:55 activity of industrial compounds in 29:56 activity of isoasarone in 29:56 activity of 3-epi-isocucurbitacin D in 29:55 activity of isomitraphylline in 29:56 activity of isopteropodine in 29:56 activity of kobophenol B (tetrastilbene) in 29:56 activity oflimonoids in 29:55 activity of lindane in 29:56 activity of marginatine in 29:56 activity of cis-nflyabenols (tristilbene) in 29:55 activity of phenylalkanoids in 29:56 activity of pipermargine in 29:56 activity of prieurianin in 29:55 activity of rohitukin in 29:55 activity of stilbenoids in 29:55 activity of suffruticosols (tristilbene) in 29:55 activity of ~-viniferin tristilbene in 29:55 activity of withanolides in 29:55 Drosophila melanogaster BI~ bioassay 29:55 alkaloids activity in 29:56 ampelopsin B (distilbene) activity in 29:55 apiole activity in 29:56 bisphenol A activity in 29:56 carnosiflosides activity in 29:55 cis-resveratrol (monostilbene) activity in 29:55 croweacin activity in 29:56 cucurbitacins activity in 29:55 deacetylpicracin activity in 29:55 diethylphthalate activity in 29:56 2,3-dihydro-3[3-methoxyichromolide activity in 29:55
2,3-dihydro-3 [5-methoxywithacnistine activity in 29:55 2,3-dihydro-3 [3-methoxywithaferin A activity in 29:55 23,24-dihydrocucurbitacin F activity in 29:55 2,6-dimethoxy-3,4-methylenedioxy- 1-(2-propenyl)benzene activity in 29:56 ecdysteroiods activity in 29:55 24-hydroxycarthamosterone activity in 29:55 industrial bioactive compounds from 29:56 isoasarone activity in 29:56 3-epi-isocucurbitacin D activity in 29:55 isomitraphylline activity in 29:56 isopteropodine activity in 29:56 kobophenol B (tetrastilbene) activity in 29:56 limonoids activity in 29:55 lindane activity in 29:56 marginatine activity in 29:56 cis-miyabenols (tristilbene) activity in 29:55 phenylalkanoids activity in 29:56 pipermargine activity in 29:56 prieurianin activity in 29:55 rohitukin activity in 29:55 stilbenoids activity in 29:55 suffruticosols (tristilbene) activity in 29:55 c~-viniferin (tristilbene) activity in 29:55 withanolides activity in 29:55 Drosophila melanogaster imaginal disc cell lines 29:33 Drug delivery system 21:615 Drug-DNA complex 23:9 Drug-effiux pump 21:158 Drummondins A-F 22:656 Drupellafragum 25:792 Drymis winteri 30:206 anti-inflammatory properties of 30:207
284
antinociceptive properties of 30:206 Dryophanta divisa 29:589 Dryopteris filixmas 26:431 DSM-IV 30:384 DSP values 17:118 Ds-penaustroside A 28:599 from sea cucumber 28:599 Ds-penaustroside B 28:599 from sea cucumber 28:599 DSPs 21:301 DTAOH 30:810,811 antagonistic effect of 30:810 8 antagonist activity of 30:811 DTAOH+DEL II 30:810 activity in tail flick test 30:810 Dt-B 25:118 Dt-C 25:118 Dt-E 25:118 DTH response 30:768,769 after infection 30:768 mononuclear cell infiltration due to 30:769 swelling due to 30:769 DTOH 30:810,811 8-antagonist activity of 30:811 antagonistic effect of 30:810 physiochemical properties of 30:811 DTOH+DEL II 30:810 activity in fail flick test 30:810 DTX-1,2,3 and 4 21:301 Duasmodactyla kurilensis 7:279,91,153 Dubamine 3:392,393 synthesis of 3:392,393 Dubinine 22:522,539 Dubioside F 15:211 Duboisia 17:395 Duboisia leichhardtii 22:742 Duboisia myoporoides 22:742 Duckweed (Lemna minor) 9:383, 384,386,387,389,390 Ducrosia anethifolia 23:341 Duct cell carcinoma of breast 1:276 Dufour glands 6:421,422, 453,454,457,458 Duguetia panamensis 9:402
Duhram 29:466 pyranoid carbasugars synthesis by 29:466 Dulcioic acid 21:690 Dulcitol 5:779 Dulucoside A 15:16;27:13,22;29:101 activity in TPA bioassay system 29:101 structure of 27:23 Dumasia truncata 25:106 Dunalia australis 20:191,194 Dunawithanine A,B 20:191 from Dunalis australis 20:191 Duocarmycin A 10:248 Duocarmycin C1 29:339 against Gram-positive bacteria 29:339 against Staphylococcus aureus 29:339 as anticancer antibiotics 29:339 in lymphocyte leukemia 29:339 in sarcoma 29:339 Duocarmycin C1 29:339 structure of 29:339 2cz,3[3-Dyhdroxy-olean- 12-ene-22,29lactone 648 13C-NMR data of 30:648 1H-NMR spectrum of 30:648 2D-NMR experiments of 30:649 HMBC spectrum of 30:649 structure of 30:649 DYN A analogues 30:818 DYN-A-(1-11)-NH2 30:809 activity in functional bioassay 30:809 (tic2)DYN-A-(1-11)-NH2 30:809 activity in functional bioassay 30:809 analytical properties of 30:809 (tic2)DYN-A-(1-13-)-NH2 30:809 activity in functional bioassay 30:809 analytical properties of 30:809 Dynorphin A 27:803 Dynorphins 22:24;27:801 ;30:806,193 as endogenous peptide opioids 30:193 biological activity of 27:801 effects of TIC insertion 30:806
285
Dysamide K 25:801 Dysamides 25:801 Dysazecine 6:487 from Dysoxylum lenticellare 6:487 synthesis of 6:487,488 Dysdercus chaluensis 22:387 Dysdercus cingulatus 22:387 Dysdercusfluvoniger 22:387 Dysdercus intermedius 22:387 Dysdercus supersetitisus 22:387 Dysidea 17:10,11;28:676 Dysidea arenaria 25:714 Dysidea avara 5:433,438;21:252; 25:693,814,815;28:668 Dysidea fragilis 6:69;28:702 nakafuran-9 from 6:69 (+)-upial from 6:65 Dysidea herbacea 4:404;21:283,284, 310,365;25:691,692,697,776,801, 815 ;26:463 ;28:142,665,666 dysideathiazole from 28:665 13-demethylisodysidenin from 28:666 13-demethyldysidenin from 28:666 isodysidenir from 28:665 immunosuppressant activity of 28:142 molluscidal activity of 28:142 9-monodechloro- 13-demethylisodysidenin from 28:666 11-monodechloro- 13-demethylisodysidenin from 28:666 polychlorinated peptides from 28:665 (22R,23 R)-22,23-methylene cholesterol from 9:37 Dysidea sp. 21:301 ;25:264,692,693, 698,815,869,896;28:666 15-acetylthioxyfurodysinin lactone from 28:667 [3-adrenoreceptor agonist from 28:668 barbaleucamide A from 28:668 benzothiazole S 1319 from 28:668 dysideaproline A from 28:668 dysideaproline B from 28:668
dysideaproline C from 28:668 dysideaproline D from 28:668 dysideaproline E from 28:668 dysideaproline F from 28:668 from Okinawa 28:668 proline-derived analogues of dysidenin from 28:668 (+)-Dysideapalaunic 6:20 aldose reductase inhibition of 6:20 from Dysidea species 6:20 synthesis of 6:21 Dysideathiazole 25:890 Dysideathiazole A 28:667 as polychlorinated amino acid derivative 28:667 X-ray analysis of 28:667 Dysideathiazole B 28:667 as polychlorinated amino acid derivative 28:667 X-ray analysis of 28:667 Dysideathiazole C 28:667 as polychlorinated amino acid derivative 28:667 X-ray analysis of 28:667 Dysideathiazole D 28:667 as polychlorinated amino acid derivative 28:667 X-ray analysis of 28:667 Dysideathiazole E 28:667 as polychlorinated amino acid derivative 28:667 X-ray analysis of 28:667 Dysideathiazole series 25:889 Dysidenin 25:889,890 Dysidia chlorea 25:801 Dysidin 28:142 antifeedant activity of 28:142 immunosuppressant activity of 28:142 molluscidal activity of 28:142 Dysinin 25:814 Dysmorphogenic 23:572 Dysodanthin A 26:212 cytotoxicity of 26:212 Dysodanthin B 26:212 cytotoxicity of 26:212 Dysosma 26:172 Dysoxylum 3:456;21:124,127
286
Dysoxylum binectariferum 21:134,147 Dysoxylum lenticellare 6:487 Dysoxylum malabaricum 21:134,152 Dyspepsia 5:754
Dytiscus marginalis 5:700 D-B cell proliferation 25:273 effect of prehispanolone on 25:273 D[3E blockers 27:283
E864-861 21:412 Earthworm 30:825,840 as antipyretic 30:825 as antitumor extract of 30:840 as diuretic 30:825 to treat clotting diseases 30:825 use in folk remedy 30:825 Earthworm fibrinolytic enzymes 30:826, 832,836,837,839,840,843 as fibrinolytic agent 30:839 as medicine 30:843 as plasmin-activator 30:839 biological function of 30:840 from Lumbricus rubellus 30:826 gene expression of 30:843 immunological results of 30:840 structure-based inhibitor modeling of 30:832 Earthworm plasminogen activator (e-PA) 30:826,843 Earthworm serine protease 30:830 Earthworm species 30:829 homologs from 30:829 site-mutation in 30:829 Earthworms 30:826 active components from 30:826 Earthworm-tissue plasminogen activator (e-TPA) 30:826,843 EBA-EA activation inhibition assay 25:58 Ebeinone 22:19 Ebelin lactone 23:503 Ebenifoline E-1 29:91 activity in TNFct assay system 29:91 Eburnamenine 13:94 Eburnamine 1:112,93,94
(+)-Ebumamine 14:636 synthesis of 14:636 Ebumamonine 5:187,189,190,632-636; 8:266;25:19 synthesis of 5:187,189,190, 632-636;8:266 (+)-Eburnamonine 14:728 from indoloquinolizidine enamine 14: 728 synthesis of 14:728 (-)-Eburnamonine 8:283;9:180;16:709710;19:143 from Vinca minor 8:283 synthesis of 16:709-710 Eburnan-type alkaloid 5:71,107-110 (-)-Eburunamenine 14:636 synthesis of 14:636 EBV 25:46 EBV assay system 25:45;29:87,88, 99,100 19-nor-Abieta-4(18),8,11,13tetraen-7-one activity in 29:100 abieta-8,11,13-trien-7-one activity in 29:99 abieta-8,11,13-triene-7(x, 15,18triol 7-acetate 29:99 cedrol activity in 29:87 10[3-hydroxycedrol activity in 29:87 12-hydroxycedrol activity in 29:87 methyl 8c~,14or, 12or,13otdiepoxy-abietan- 18-oate activity in 29:99 EBV bioassay systems 29:100 EBV genome 30:592 expression of 30:592 EBV inducer 30:592 n-butyrate as 30:592 EBV inhibitor 30:592 1,2,3,4-dehydrodeoxypo dophyllotoxin as 30:592 1,2,3,4-dehydropodophyllotoxin as 30:592 6,7-demethylenedeoxypodophyllotoxin as 30:592 bursehernin as 30:592 epimagnolin as 30:592
287
Hernandia ovigera as 30:592 podorhizol as 30:592 EBV-EA activation 21:642,643,645; 25:59 induced by TPA 25:59 EBV-EV activation 30:695 effect of Tripterygium wilfordii 30:695 inhibition of 30:695 Ecballium EETI-II 29:615 Ecballium elaterium 20:13 ;29:615 Ecdysone 2:169;25:515 ot-/[3-Ecdysone 20:248 c~-Ecdysone 26:700 Ecdysone synthesis 25:242 Ecdysteroid agonists 29:22 8-O-acetylharpagide as 29:24 against diphtera 29:22 against lepidoptera 29:22 as elicitors 29:23 as insecticides 29:22 bisacylhydrazines as 29:22 disadvantages of 29:22 3,5-di-tert-4-hydroxy-Nisobutylbenzamide as 29:24 from Ajuga reptans 29:24 in gene switch systems 29:23 maocrystal as 29:23,24 nonsteroidal 29:22 4-phenylamino- 1,2,3,4tetrahydroquinolines as 29:24 QSAR studies of 29:22 RG-102240 (GS-E) as 29:23 RH-0345 (halofenozide) as 29:23 RH-2485 (methoxyfenozide) as 29:23 RH-5992 (tebufenozide) as 29:23 2 [3,313,20R,22R-tetrahydro xy-25fluoro-5 [3-cholest-8,14-dien-6one as 29:18,19 Ecdysteroid antagonists 26:555 Ecdysteroid antagonists ampelopsin B 29:54 activity in BH bioassay 29:52 applications of 29:56 as pest control agents 29:56
biomedical applications of 29:59 bisphenol A as 29:54 classes of 29:52 cucurbitacins as 29:53 diethylphthalate as 29:54 2,3-dihydro- 3 [3-hydro x y withacnistine as 29:54 environmental protection by 29:59 from Hemsleya carnosiflora 29:53 from Iberis umbellata 29:53 24-hydroxycarthamosterone as 29:54 lindane as 29:54 pipermargine as 29:54 preurianin as 29:54 cis-resveratrol as 29:54 rohitukin as 29:54 use in crop species 29:57 use in gene switching technology 29:59 c~-viniferin as 29:54 Ecdysteroid phosphates 19:641 Ecdysteroids 19:631;26:699,700;29:3 accumulation in spinach 29:8 affinity labelling of 29:20 allelochemical properties of 29:8 analogues of 29:21 as chemical defence 29:8 biosynthesis of 19:629-634 chemistry of 29:17 3-dehydroecdysone as 29:7 25-deoxyecdysone as 29:7 detection in invertebrates 29:4 dimeric type of 29:21 docking studies of 29:49 effects in Homosapiens 29:9 effects on bile acid production 29:9 effects on cellular proliferation 29:9 effects on differentiation 29:9 effects on insect growth 29:7 effects on mammalian cells 29:39 effects on physical performance 29:9 effects on vertebrates 29:60
288 for gene-switching systems 29:21 from Ajuga decumbens 29:60 fluorescently-tagged 29:20 hormonal roles of 29:61 4a-hydroxy-7en-6-one chromophore of 29:4 20-hydroxyecdysone as 29:4 makisterones as 29:7 mode of action of 29:4 molecular modeling studies of 29:44,45 natural analogues of 29:18 non-natural analogues of 29:18,19 of arthropods 29:4 pharmacophore hypothesis for 29:46 polypodine B as 29:7 ponasterone A as 29:7 poststerone as 29:7 potency of 29:46 pterosterone as 29:7 QSAR of 29:4,43 receptors of 29:14 role in crop protection 29:17 role in metamorphosis 29:5 role in moulting 29:5 role in reproduction 29:5 rubrosterone as 29:7 taste receptors for 29:17 SAR of 29:3,16 structural diversity of 29:4,18 titres of 29:6 total synthesis of 29:17 turkesterone as 29:7 3-epi-Ecdysteroids 19:634 Ecdysterone 20:114;26:700 Ecgonine 22:7,722 (-)-Ecgonine 22:721 Echiguanine 15:458-461 Echiguanine A and B 15:459 Echimidine 26:874,876 Echinacea augustifolia DC. 22:393; 24:689;29:684 Echinacea sp. 29:683 Echinaster brasiliensis 15:55 Echinaster luzonicus 7:294 Echinaster sepositus 7:294,298;15:59
Echinasterosides BI,B2 7:298,300 Echinatin 28:228 biological activity of 28:228 Echinatine N-oxide 1:275 Echinocandin B 22:249 Echinocandins 22:62,248 Echinocaulone 22:634 Echinochloa crusgalli (L.) 27:217 Echinochloa frumentacea 24:57,60 Echinoclasterol sulfate 28:705 as antifungal substance 28:705 as cytotoxic steroid 28:705 from Echinoclathria subhispida 28:705 phenethylammonium salt 28:705 Echinoclathria sp. 25:814 Echinoclathria subhispida 28:705 Echinoclathrine B 25:814 Echinoclathrine C 25:814 Echinocystic acid 7:434;21:634,643; 25:60;30:747 structure of 30:747 Echinocystic acid glycoside 21:657 Echinocystis lobata 29:615 Echinocystis macrocarpa 7:330 Echinodermata 7:265,266 Echinoderms 7:265-316;21:314;28:716; 30:526 classes of 28:716 histidine derivatives from 28:716 living species of 28:716 metabolites of 28:716 Echinodictyum sp. 25:900;28:697 echinosulfonic acid A from 28:697 echinosulfonic acid B from 28:697 echinosulfonic acid C from 28:697 echinosulfone from 28:697 Echinoidea 7:43,103,104,265,282-285 Echinolactones A,B 7:136 from Echinophora lamellose 7:136 Echinolone 22:384,393,395 Echinophora lamellosa 7:136 echinolactones A,B from 7:136 glycyrrhetic acid from 7:136 smilagenin from 7" 136
289
Echinops echinatas 22:117,119 Echinoside A 7:269,271,280 Echinoside B 7:269,271,280 Echinosulfone A 25:900 Echinosulfonic acid A 25:900 Echinothuridae 7:283 Echitamidine 1:36 20-epi-Echitamidine 1:36 Echium piantagineum 19:247 Echium sp. 26:872 Echium vulgare 22:520 Echium wildpretti 26:874 Eciton hamatum 5:250 Ecklonia stolonifera 19:553 Ecklonialactone A 19:554 cytotoxic activity of 19:554 isolation of 19:553 relative stereochemistry of 19:553 Ecklonialactone B 19:553 Ecklonialactones 19:552 Ecological consequences 21:108 Ecology 21:364 of marine isocyanides 21:364 Economic viability 28:345 of 14[3-methyl- 14-c~-hydroxyMFA 28:345 of 15cx-methyl- 14et-hydroxyMFA 28:345 ECs 24:888-890 by magnosalin 24:888-890 Ecteinascidia turbinata 21:322;23:253; 25:707,825;28:640,641 antitumor activity of 28:640 ecteinascidins from 28:640,641 Ecteinascidins 10:248,249;21:321, 322,323,743 ;23:253,255 ;25:707,825 biogenesis of 23:253,255 Ectocarpene 21:305,306 Ectocarpus siliculosus 21:305,306 Ectoprotein CD38 25:535 Ectyoplasia ferox 26:66 ED-71 30:492 synthesis of 30:492 Edema 22:115;25:46 induced by 25:46 Edema inhibition (HPA) 25:46 by 12-O-hexadecanoyl- 16-
hydroxy phorbol- 13-acetate (HHPA) 25:45 Edema relief 23:362 by coumarin 23:335,353,356, 357,368,376,393,550,553 Edgar-Greene-Crabbe' intermediate 14:365 ' Edman degradation 2:33;9:489,499,549, 551 ;19:797;25:437 Edmonston A 21:665 EDTA 21:540;30:836 Edudiol 28:228 biological activity of 28:228 y-Eduesmol 21:583,584 Edulinic acid 23:674 Edulinine 22:536,542 (+)-Edunal 4:385,386 Eedeoma pulegioides L. 22:522 EFE 30:835,838,840-842 as plasminogen activator inhibitor 30:842 assays of 30:835 by photoreaction 30:841 fibrinolytic medicine from 30:842 in acute cerebral thrombosis 30:842 in acute diseases 30:842 in cerebrovascular thrombus 30:842 in peripheral limbs arteriovenous thrombus 30:842 in prevention of blood clotting 30:842 in radiation therapy 30:841 inhibition by fibrin 30:838 role in dissolution of thrombus 30:842 to treat AMI 30:842 use of antitumor drugs 30:840 EFEa 30:830,831 crystallization of 30:831 homology of 30:830 X-ray analyses 30:831 EFE-immobilized polyurethane surface 30:841 as antithrombogenic agent 30:841 effect on platelet activation
290
30:841 effect on platelet adhesion 30:841 Effective insect growth inhibitors 26:858 calopeptin as 26:858 dehydrodiisoeugenol as 26:858 galbacin as 26:858 galbegin as 26:858 licarin as 26:858 licarin B as 26:858 sesamin as 26:858 sesamolin as 26:858 veragensin as 26:858 Effector-receptor complexes 27:379 Effusanin A 15:173 from Rabdosia nervosa 15:173 Effusanin B 15:173 from Rabdosia langituba 15:173 from Rabdosia ternifolia 15:175 Effusanin E 15:173 from Rabdosia nervosa 15:173 from Rabdosia ternifolia 15:175 Eflornithine 26:787,792 EGb 28:185 activity against MPTP 28:184 effects on neuroendocrine system 28:185 effects on phospholipid metabolism 28:185 protective activity of 28:184 EGF receptor kinase 25:797,870 Egg white lysozyme 2:31,32,34,36 Egregia menziessi 19:554 EGTA 25:490 EGTA-Ca 2+ buffer system 25:490 EGTA-containing buffer 25:491,492 EGTA-treated plasma membrane 25:492 Ehrlich ascites carcinoma 25:939,957; 26:303 Ehrlich ascitis tumor cells 21:664 Ehrlich carcinoma 19:609;23:130 Ehrlich products 13:300 Ehrlich's reagent 9:592;19:755;26:1277 Ehuazulene 14:315 Eichhornia crassipes 26:359 (5Z,9Z)-5,9-Eicosadienoic acid 26:80
(11Z,15Z)-I 1,15-Eicosadienoic acid 26:89 (10Z, 15Z)-I 0,15-Eicosadienoic acid 26:90 total synthesis of 26:90 Eicosanoid 25:274,520,693,939 Eicosanoid production 25:615 Eicosanoid signalling 25:374 Eicosanoids 22:4 Eicosatetrainoic acid 22:126 9-Eicosene 26:361 Eicospentaenoic acid 19:552 biosynthesis of 19:552 4-Eicosphingenin 18:786 Eicosyl ferulate 26:666 elF4E-dependent mRNA translation 25:526 Eight-carbon sugars 4:172-175 by epoxide route 4:172-175 by osmylation 4:163-175 synthesis of 4:163-175 Eight-membered marine compounds 6:37 biosynthesis of 6:37 by cyclopropanone sliding reaction 6:37,210,218-220, 224-226,234 Eight-membered rings 3:77 by anionic oxy-Cope rearrangement 3:77 by [4+4] annulation 3:78 by dicarbonyl coupling 3:81 by Michael additions 3:83 by Nicholas reactions 3:83,84 by retroaldolization of enonenephotoadducts 3:74,75 by ring contractions 3:76,77 by transannular acylation 3:81, 82 from allylchromium-carbonyl coupling 3:81 synthesis of 3:73-111 Eilatian 25:532 Eilatin 10:247;23:276 Eimeria 26:804 Eimeria tenella 17:376 EIMS 30:584,587 of (-)-hernone 30:587 ofherveline A 30:583
291
Eiocosapentaenoic acid 28:565 in fish oils 28:565 Eisenia andrei 30:828 from Lumbricidae family 30:828 Eisenia fetida 30:826,828,829,832 EFE component A of 30:829 F-II homolog of 30:832 fibrinolytic activity of 30:826 from Lumbricidae family 30:828 isozymes of 30:826 Ekebergia senegalensis A. 2:117,118, 120,269;22:520 for epilepsy 22:520 Ekeberginine 2:117-120,95 Ekebergolactone A 2:269,270 Ekebergolactone B 2:269,270 long range dd correlation spectrum 2:269,270 NOE difference spectra 2:272 2D NOESY spectrum 2:272 Ekesenin 2:117 Elabunin 23:703 Elaeocanine 12:277;454 synthesis of 12:454 Elaeocarpus ganitrus 22:520 for epileptic fits 22:520 Elaeocarpus sphaericus 22:520 for epilepsy 22:520 Elaeocarpus tuberculantus 22:520 for epilepsy 22:520 Elaeocarpusin 4:718 thermolysis of 4:718 Elaeodendrol 7:152 from Elaeodendron glaucum 7:152 Elaeodendron buchananii 23:669 insect antifeedant sesquiterpenes from 23:669 Elaeodendron capense 23:655 Elaeodendron glaucum 5:152,757; 23:655 Elaeodendron schiveinfurthianum 23:655 (+)-Elaeokanine A 1:283,284,286,288, 289;12:189 asymmetric synthesis of 12:351, 352 from (+)-elaeokanine C 12:352 synthesis of 1:283,284,286,
288,289:12:189;13:487,488; 16:460 Elaeokanine B 1:284,286,289 synthesis of 1:284,286,289 (+)-Elaeokanine C 12:277,351,352 asymmetric synthesis of 12:277,351,352 (+)-elaeokanine A from 12:352 synthesis of 16:476 Elaeokanine C 12:289 from Elaeocarpus kaniensis 12:289 from 1-(methoxycarbonyl)-2methoxy pyrroline 12:292 synthesis of 1:277,278,282,284286;12:289-293 Elaeokanine E 12:277 Elaiophylin 16:713-714;26:453 synthesis of 16:713-714 ELAM-1 expression 30:70,71,291 baicalein effect on 30:291 induction by TRAP 30:70,71 Elaodendrum 18:741 Elasnin 5:590,591 Elastase 2:35; 30:832 characteristic of 30:832 of chymotrypsin 5:590 of human granulocyte 5:590 ofpancrea 5:590 of trypsin 5:590 Elastase inhibitor 5:590 from Streptomyces noboritoensis KM-2753 5:590 Elastatinal 30:836 Elatian 25:709 Elatosides 21:675 Eldana saccharina 11:414 eldanolide from 3:168;11:414 Eldanolide 11:414 from Eldana saccharina 11:414 from (R)-pinanediol methylboronate 11:414 synthesis of 11:414 (-)-Eldanolide 14:272,273;16:240,692 from levoglucosenone 14:272, 273 synthesis of 14:272,273;16:240, 692
292 (+)-Eldanolide 16:692 synthesis of 16:692 Electrically evoked contractions 30:801 Electrochemical detection 21:50 Electrochemical oxidation 14:325 of azulenes 14:325 of guaiazulene 14:325,326 Electrocyclic rearrangement 6:72 Electroenzymic reactions 20:877 Electrolysis 19:35 Electromicrobial dehydrogenation 20:867 Electromicrobial reductions 20:877 Electron chains 21:98 Electron mediators 20:821-824 n-Electron SCF-CI-DV MO method 17:39-40,45,47 Electron transfer 27:749 4,4'-bis-jatrorrhizine (v) 27:749 oxidative halogenation 27:750 oxygen transfer 27:751 N-dealkylation 27:754 O-dealkylation 27:754 Electron-demand 17:553 Electrophile-Responsive Element 26:951 Electrophiles 19:464;30:431 1,4-Electrophilic addition 1:487,488 Electrophoresis 19:648 Electrophoretic mobility 9:541 Electrophoretic patterns 5:838 Electrophoretic studies 5:836 Electrospray ionization 9:487,499,502 Electrospray Ionization Interface (ESI) 19:750 Electrospray ionization mass spectrometry 21:556 Eledoisin 27:800 Eleganediol 20:26 Elegansamine 15:484 from Gelsemium elegans 15:484 Elemane 7:168,216 by [2+2] cycloadditions 6:15 Elemanolide 7:216;23:160 from Artemisia hispanica 7:216 Elemanolides 24:72,91-98,103,104 [3-Elemene 21:276;23:545 Elemol 15:244;21:595
[3-Elemol 14:406-413 synthesis of 14:406-413 Elenoic acid 3:254,255 synthesis of 3:254,255 Elenolide 7:442,477,478 Eleocarpus 27:250 Eleocharis microcarpa 26:361 Eletrophoretic mobilities 5:839-841 Elettaria cardamonum 21:614; 26:474;27:374 Elettaria sp. 21:599 Eleusine coracana 29:601,617 Eleuterin 4:591,592 Eleutherobia aurea 25:690 Eleutherobin 30:5 as microtubule stabilizing agent 30:5 Eleutherococcus senticosus Harms (A canthopanaxsenticosus) 5:505,514,515,521,523,524,544 Eleven-carbon sugars 4:188 by osmylation 4:188 synthesis of 4:187-190 Eliamid 28:146 cytostatic activity of 28:146 fungicidal activities of 28:146 nematocidal activity of 28:146 Elicitins 25:395,396 Elicitins receptor 25:396 Elicitor activity 25:397 Elicitor-active structure 25:394 Elicitors 25:393,394;27:61 syn-Elimination 11:184,188 [3-Elimination 11:184;24:8,9,10,13,15, 23 antiperiplanar 12:17 of 3-mesyloxy-l-threonate 12:17 stereoselective 12:17 Hfinnig base-mediated 14:291, 292 1,4-Elimination 11:187 Elimination 6:540;16:366,416 by molybdenum (VI) oxodiperoxo complexes 4:344, 345 by Sharpless procedure 4:29,30 enantioselective epoxidation 4:29,30,343-345 of non-functionalised olefins
293
4:344,345 thermal 4:44,45 ~{-Elimination 19:165 [3-Elimination reaction 10:593 Elimination with KN(SiMe3)2 1:440 Elimination-addition mechanism 14:457 Eliminative cleavages 1:618,619 ELISA 15:363-366;30:774 Elkin-Ahn-Houk model 30:437 for asymmetric induction 30:437 Ellagetannins 20:276 Ellagic 20:276 Ellagic acid 23:536,550,746,750; 25:545,938;26:359;27:413,755; 28:280;29:571,579 as inhibitor of PKA 25:550 as inhibitor of PKC 25:550 derivatives of 23:536,550 effects on ACE 29:579 inhibition of Candida albicans aspartic protease 29:751 inhibition of pepsin by 29:571 structure of 28:280 Ellagitannin oligomers 23:395-453 ~3C-NMR data of 428 ~H-NMR data of 23:426 biogenesis of 23:395-453 chemical perspective of 23:395453 classification of 23:398 discovery of 23:395 CD data of 23:433 CD spectroscopy of 431 mass spectroscopy of 423 structure elucidation of 23:423 Ellagitannine 17:360;23:750,752 Elliptically polarized light 2:154 Ellipticine 22:9,27;26:828,829 Ellipticine derivatives 6:510,511, 515,516,520 Ellipticine derived alkaloids 6:506-520 Ellipticine-type alkaloids 5:89,90 Ellipticity 2:153,2:160 Elliptinium acetate 22:28 Elliptinone 2:212,214,754 Elsinan 5:278,754 Elsinoe leucospila 5:278 R-(+)-Eludanolide 19:134 Elymoclavine 11:200
Emaciation 26:690 Emanthidine 26:614 Emarginatine A 23:679 Emarginatine B 23:679 Emarginatine C 23:679 Emarginatine D 23:679 Emarginatine E 23:679 Emarginatine F 23:679 Emarginatine G 23:679 Emarginatinine 23:679 EMBASE 19:758 Embelia schimperi 30:325 5-O-methylembelin from 30:325 Embelin 7:182 Embryolethality 23:577 ofjervanes 23:577 of solanidanes 23:577 of spirosolanes 23:577 Embryonic central nervous system 30:378 role of serotonin (5-HT) in 30:378 Embryonic development 23:563-589 of Veratrum alkaloids 23:563-589 Ememogin 15:143,152,160,175 Emericalla uniquis 25:780 Emericellopsis sp. 21:224 Emetic effect 26:239 Emetine 13:92;22:29 (-)-Emetine 14:565 synthesis of 14:565 (+)-Emetine 18:330 amoebicidal activity of 6:485 EMIBD 24:954-956 bioactive compounds of 24:954-956 bioactivity of 24:954-956 Emicarpus anacardium L. 22:532 Emmons-Horner-Wadsworth 29:471 carbaaldopyranoses synthesis 29:471 Emodin 9:400;22:467-480,608,609,610, 617,620,623 ;23:798;25:543,544,547, 546;26:637 ;30:306 structure of 30:306 Emodin-8-D-glucoside 22:609,610 Emodin-8-O-fl-D-glucoside 22:617,618,619
294
Emphibian skin 27:797 bombesin analog from 27:797 Empidonnax hammondii 5:836 Enamide photocyclization 3:404-406 non-oxidative 3:404-406 reductive 3:407-410,414 Enamide-aldehyde cyclization 14:772-779 Enamidines 6:430,431 Enamine formation 1:452 Enamine related substrates 18:315-386 Enamine-aldehyde cyclization 14:785-787 (+)-corynoline by 14:785-787 (+)-11-epicorynoline by 14:785-787 (+)- 11-epiisocorynoline by 14:785-787 (+)-isocorynoline by 14:785-787 Enamines 14:791-793 acid-catalyzed 14:791-793 cyclization 14:791-793 reactions with acetylenes 3:95,96 singlet oxygen cleavage of 8:261 [3-Enamino imine substrate 18:343,366 [3-Enaminoesters 14:738 cyclization of 14:738 dehydropyrrolizidines from 14:738 Enaminosulfoxides 6:317,318 in c~-ketoacid derivatives synthesis 6:317,318 Enantio-13-epi-labdanolic acid 25:252 Enantiofacial selection 13:70-73 asymmetric synthesis by 13:70-73 Enantiomeric chiral auxiliary 12:342 Enantiomeric composition 27:374, 377,385 in conifers 27:370 of monoterpenoids 27:370,374 of et-pinene 27:385 Enantiopinifolic acid 25:252 Enantioselective- 6:445,446 epoxidation 6:445,446 fermentative reduction 6:158 hydrolysis 13:54 Michael addition 6:86
oxidation 13:54 reduction 13:54 Enantioselective chromatographic analysis 27:361 Enantioselective hydrolysis 12:337 with Candida cylindracea 12:337 with Pseudomonas sp. 12:337 Enantioselective reactions 16:559 Enantioselective reduction 18:288 Enantioselective synthesis 6:39,40,86, 87,443;12:281,311,312;14:14-17, 546,741,742 ;22:235 ;24:185 ;29:244, 490,492 of (-)-( 1R-8aS)-1-hydroxyindolizidine 12:281 of (-)-slaframine 12:311,312 of (-)-y-rhodomycinone 14:14-17 of (+)-( 1S,8aS)-1-hydroxyindolizidine 12:281 of (+)-stoechospermol 6:39,40 of 2,5-dialkylpyprrolidine ant alkaloids 6:443 of 7,20-diisocyanoadociane 6:86,87 ofepi-lupinamine 14:741,742 of kaurane-type diterpenes 14:546 o f lupinamine 14: 741,742 ofsolenopsin B 6:429,430 of spirovetivane-type sesquiterpene 14:546 of (+)-albicanol 24:185 of carbaoxirose/carbaoxetoses 29:490,492 of Physarum polycephalum 29:244 Enantioselective yeast hydrolysis 12:338 Enantioseparations 27:387 of monoterpenoids 27:387 Enantio-sigmosceptrellin-A 9:28,29 Enantiospecific dehydrogenation 24:742 Enantiospecific reduction 24:742 Enantiospecific synthesis 4:625;12:313, 314,317,318
295 Enantiotopic discrimination 13:60-62 asymmetric synthesis by 13:60-62 Encephalartos 26:1157
Encephalartos friderici-guilielmi 26:1158
Encephalartos longifolius 26:157 Encephalitis 30:408 vaccination against 30:408 Encephalitizoon inteslinalis 26:788 Encephalocele 7:20,21;23:570 Endecaphyllins 27:522 Enders 29:389 steganes synthesis by 29:389 Enders reagent 4:327 Endiyne antibiotic 10:154 Endlicheria dysodantha 26:211 dysodanthin A&B from 26:212 megaphone acetate from 26:212 Endo and exo-bicyclic compounds 10:138,139 Endo benzyloxy group 12:340 Endo-anhydroverticillol 12:182 Endocannabinoid analogues 30:198 as cannabinoid ligand 30:198 Endocrine control 19:628 Endocrine function 27:314 Endocrine system 22:369 10-Endoe endon cyclization 10:219 8-Endoe endon cyclization 10:219 Endogenous abscisic acid 27:322 Endogenous defense signal system 25:397 Endogenous hepatoprotective factor 25:471 Endogenous peptide opioids 30:193 role of dynorphins 30:193 role of endorphins 30:193 role of enkephalins 30:193 role of nociceptin 30:193 role of OLR- 1 30:194 role of opioid receptors 30:193 Endomorphins 30:799 Endomyces spp. 2:323 Endomycopsisfibuliger 5:280,282 Endonuclease 13:290 Endonuclease restriction map 2:354 Endoperoxide rearrangement 4:419,420 Endoperoxide synthase 9:571
Endophytic fungi 21:91;24:933-972 bioactivity of 24:944-950 brine shrimp toxicity of 24:944-950 Endoplasmic reticulum 25:548 Endopolygalacturoase 26:1133 Endoproteinases 25:375 Endoproteolytic proceesing 25:387 ENDOR spectroscopic method 30:540 in free radical studies 30:540 [~-Endorphin 27:802,803 Endorphins 22:23;27:20,72,801 ;30:193 as endogenous peptide opioids 30:193 biological activity of 27:801 Endospermum diadenum 29:100 Endosymbiosis 6:134 Endothelial leukocyte adhesion molecule-1 (ELAM-1) 30:70 expression of 30:70 Endothelin A 25:841 Endothelin antagonism 26:237 Endothelin converting enzyme (ECE) assay 28:699 activity of halistanol disulfate B in 28:699 Endothelin-I 25:841;26:267 Endothelium 30:410 Endothelium-dependent NO/EDFR 30:76 production of 30:76 Endothelium-Derived Relaxing Factor 26:951 Endotoxemia 25:463 Endotoxin-mediated pathway 23:140 Endotoxins 28:518 chemistry of 28:518 Endo-fl-l,6-galactanase 25:438 Endo-fl-galactosidase 25:436 Ene cyclization 1:17,159,294 Ene reaction 10:59 of 17(20) Z/E pregnenes 10:59 intramolecular 3:21;11:91,108; 16:17,246 of acryloyl chloride 16:246 of N-sulfoxyl imines 16:17 metallo-variant of 3:21 of malondialdehyde 6:225,226 Enediyne chromophore 25:796
296
Ene-quinone-methide 5:744,747,749 E-Nerotidol 25:164 Ene-type reactions 1:616,617 Engelhardtia chrysolepis 15:31; 27:18;29:583 huangqioside E from 27:18,35 neoastilbin from 27:18,35 Engler synthesis 14:692-695 Engorged toxicity 28:400 from Hibiscus rosa-sinensis 28:400 from Nicotiana tabacum 28:400 from Ocimum micranthum 28:400 from Quassia simarouba 28:400 fromRicinus communis 28:400 from Salvia serotina 28:400 from Spigelia anthelmia 28:400 from Symphytum officinale 28:400 from Stachytarpheta jamaicensis 28:400 Enkephalins 21:72;22:23;25:533; 27:801 ;30:193,817 analgesic activity of 30:817 as endogenous peptide opioids 30:193 biological activity of 27:801 Enmein 15:173 from Rabdosia lophanthoides 15:173 from Rabdosia sculponeata 15:174 Enmenol 15:172 from Rabdosiajaponica 15:172 Enniatin A&B 26:482 Enniatins 6:219,220,213,519,5339535;13:533 Enoate triol 12:15 enantioselective 12:15 from (-)-quinic acid 12:15 synthesis of 12:15 ENOD40 25:368,379 ENOD40 peptide 25:381 Enol ether 30:441 cleavage of 30:441 Enol ether reaction 4:437 with azetidinone 4:437
enterobacteriaceae 4:196 triheptoses in 4:196 Enol lactone 8:297 Enol silyl C-glycoside 10:342 Enol silyl ether (enolate) 12:160,161, 163,164 3-Enol- 17,21-triacetate 9:416-418 Enol-acetate nucleosides 4:237 synthesis of 4:237 Enolacetylation 30:486 of trienone 30:486 Enolate alkylation 14:738 Enolate Claisen rearrangement 10:340 Enolate formation 10:410,411 LDA-mediated 10:410,411 of 7-1actone 10:410,411 5-Enolpyruvylshikimate 3- phosphate synthase 11:185,187 A2,3Enone 12:25 ~,[3-Enone 30:444 derived from D-mannose 30:444 Enone 8:176-178,181,183-186,191; 11:344 E-Enone 8:177 Z-Enone 8:177 Enone epoxidation 10:36 Enone-alkene photocycloadditions 6:33,34 Enones 10:352-354 Enopeptins 21:374 Enopeptins B 21:409 Enoyl CoA reductase 11:191 from Streptomyces collinus 11:191 Entada 15:191,214 Entagenic acid 25:60 Entamoeba histolytica 6:398,485; 23:473 ;26:836,1063 Entandrophragma 9:102 Entandrophragma utile 9:95 Enterobacter cloacae 12:63;25:258, 259;26:402,1091 Enterobacter sp. 25:170,171 Enterobactin 9:537 Enterococcus faecalis 10:117,400; 20:712 ;25:776,778 Enterococcus faecium 25:776 Enterodiol 26:191
297
Enterofuran 26:191 Enterolactone 5:461 ;26:192 Enterolactone lignans 26:209 Enterolobium contorsiliquum 29:604 Enterolobium EcTI 29:604 Enukokurin 2:262,265 Enveloped virus 21:662,665;30:395,401 inhibitor of 30:395 Enyne 8:277-281 Enyne carbocyclization 12:263 Enzymatic activities 21:168; 24:981-1006,1077 alginasic 24:995-998 amylase 24:995-998 arabinosidasic 24:994-998 cellulasic 24:983-998 chitinasic 24:999-1001 galactosidasic 24:994-998 gelatinasic 24:999-1001 lipases 24:1005 lipasic 24:999-1001 nitrate reductases 24:999-1001, 1005 pectinasic 24:995-998 polysaccharides 24:1003-1004, 1009,1077 proteases 24:1005 redox enzymes 24:983-987,1003 xylanasic 24:983-993 Enzymatic aldol condensation 10:535, 536;11:216 Enzymatic cleavage 21:167 Enzymatic coupling 2:392,394,396, 398,399,401 Enzymatic cyclization 7:100 Enzymatic degradation 27:191-196 of benzoxazinoid acetal glucosides 27:191-194 Enzymatic enantiotopic differentiation 13:624 Enzymatic hydrolysis 6:150;7:268,270; 13:54,56,57 ;16:291 ;21:165 of geniposide 16:291 of diacetylenic allo-xanthin 6:150 of soya bean flour 9:412,413 Enzymatic oxidation 21:499 of sulfides 14:517,518 sulfoxides from 14:517,518
Enzymatic reaction 16:108,110,111 Enzymatic reduction 12:338,58 Enzymatic synthesis 30:423 of oligonucleotides 13:279,280 Enzymatic transesterification 13:55 Enzymatically controlled 11:287 Enzyme 23:377;27:378;30:423,430, 835,840 activity of 27:378 coumarin effect on 23:335,356, 357,353,368,376,393,550,553 for synthesis of carbohydrates 30:423 inhibition of 30:154-156 Enzyme activities 2:389,390,392,394, 396,399;21:748;23:12 Enzyme activity inhibition 21:589 Enzyme catalyzed conversion 2:3.72 Enzyme catalyzed reactions 7:29 Enzyme inhibition 24:845 biological activity 24:845 Enzyme inhibitors 22:29 Enzyme inhibitory activity 21:398,585; 27:850 Enzyme intermediates 27:740 reactivity of 27:740 ENZYME program 17:493-494,500 Enzyme-aided enantioselective acylation 18:428 Enzyme-aided enantioselective hydrolysis 18:426-428 Enzyme-carbohydrate interactions 7:29-86 Enzyme-catalyzed acylation 12:346 Enzyme-catalyzed reactions 9:612,176 Enzyme-inhibitory properties 7:14 Enzyme-linked immunosorbent assay 24:142;26:1125 Enzymic activity 28:257 of plant polyphenols 28:257 Enzymic galactosylation 10:469 Enzymic generation 27:77 oftrihydroxy fatty acids 27:77 Enzymic metabolism 23:12 EPA 30:65 from carp oil 30:65 Epatorenone 5:28-30 Epchrosine 6:505,521
298 Epchrosine (19R,20R-epoxy-apparicine) 9:172,173 (-)-Epedradine A 9:76 Epeolus cruciger 5:223,224,231,253 Epeolus variegatus 5:223,224,231,253 Ephedra sinica 5:505 Ephedra spp. 26:235 ephedradine B from 26:235 Ephedradine A 9:75 Ephedradine B 26:235 /-Ephedrine 18:601 Ephedrine 21:57,84 (-)-Ephedrine 22:279 1-Ephedrine 5:505 Ephedrine 5:751,752 W-Ephedrine 5:752 24-Epi-l a,25(OH)2D2 30:494 binding affinity of 30:494 23-Epi-25-deacetylrifamycine 23:56 10', 1 l'-Epiabsinthin (guaine sesquiterpene dimer) 29:574 effects on HIV- 1 protease 29:574 Epiacetylaleuritolic acid 7:144,145 16-Epiaffinine 9:181,182 19-Epiajmalicine 9:171 (+)-Epialloyohimbane 14:710,711 synthesis of 14:710,711 Epialloyohimbane 25:5,20 Epialpinolide 23:815 (+)- 12-Epiaplysistatin 16:705 synthesis of 16:705 Epiapotrichothecenes 13:520 3-Epi-aristoserratenine 9:185,194 (-)-Epiasarinin 26:260 Epiaschantin 18:552 from Hernandia ovigera 18:552 (+)-Epiaschantin 26:201,267;30:568, 590,595 as platelet aggregation inhibitor 30:594 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:589 1-Epiaustraline 10:567,568 3-Epiaustraline 10:567,568
2-Epiavermectin Bla derivatives 12:15 (-)-Epibatidine 19:69;21:95 synthesis of 19:69 (+)-Epibatidine 19:69 synthesis of 19:69 Epibatidine 21:51;22:18;25:757,791, 792 Epibionts 22:79 24-Epibrassinolide 16:322;18:509,511, 529,530,533,534 24-Epibrassinolide 19:247;25:425,426 3-Epibryonol 22:124 Epi-calyxin B 23:805 Epi-calyxin C 23:806 Epi-calyxin D 23:806 Epi-calyxin G 26:902 7-Epicarminomycinone 14:20 1-Epicastanospermine 10:556 synthesis of 10:556 6-Epicastanospermine 10:567 24-Epicastasteron 18:503,511,514, 529,530,533 24-Epi-catasterone 25:425 by Bayer-Villager oxidation 25:425 (-)-Epicatechin 21:498,499,503; 22:319;23:745,747;25:541 Epicatechin 20:782;22:362,645, 663 ;23:743,749 ;30: 83 as tannin 30:83 (-)-Epicatechin (2R,3R, 5,7,3 ',4'tetrahydroxyflavan-3-ol) 29:579 effects on ACE 29:579 Epicatechin 3-gallate (flavan-3-ol) 29:585 effects on proteasome CHY-like activity 29:585 (-)-Epicatechine gallate 22:319;25:612; 27:416;26:770 Epicatechin-3-gallate 26:359 (-)-Epicatechin-3-O-gallate (flavan-3-ol, gallotannin) 29:579,582 effects on ACE 29:579 effects on collagenase 29:582 effects on MMP (gelatinase) 29:582 Epicatechins 26:748,75] Epicathenamine 9:171 (+)-A2-8-Epicedrene 19:136-137
299 8-Epichromazonarol 15:291,298 Epicinnzeylanol 26:850,853 Epicoccum purpurascens 21:221 Epicodisterol 9:42 Epicorazine A,B 21:221 (+)-3-Epicorynanthediol 14:709,710 synthesis of 14:709,710 13-Epicorynantheidol 25:24 (+)-11-Epicorynoline 14:785-787 cyclization 14:785-788 from corysamine 14:785-787 oxidation of 14:788,789 synthesis of 14:785-787 through enamine-aldehyde 2'-Epicycloisobrachycoumarinone epoxide 26:798 Epidaunomycinone 14:7 7Epidermal growth factor 21:135;25:766 Epidermal growth factor receptor 27:847 Epidermoid carcinoma 25:266 Epidermophyton fluccosum 26:227,228 Epididymal sperum 27:311 14-Epidihydrocochlioquinone B 26:460 Epidihydrophysalin C 20:189,20:247 from Witharingia cocculolides 20:189 4E- 1-Epidihydroridentin 27:567 4Z- 1-Epidihydroridentin 27:567 Epidioxy-substituted non-diterpenes 25:688 Epidithodioxopiperazines 25:901 16-Epi-E-isositsirikine 9:170,171,173 11-Epi-ephedradine A 9:75,76,78 Epiepoformine 4:612,613 synthesis of 4:612,613 Epiepoxydon 4:612 synthesis of 4:612 (-)-Epieudesmin 26:201 Epifrenolicin 4:592,594,595 Epigallocatechin 22:325,362;30:83 as tannin 30:83 (-)-Epigallocatechin gallate (EGCG) 25:470,546 (-)-Epigallocatechin 23:745;27:416 structure of 27:418 Epigallocatechin (413-+8, 2[3-+0-7)epicatechin 29:572
effects on HIV- 1 protease 29:572 Epigallocatechin 26:748;29:585 effects on proteasome CHYlike activity 29:585 (-)-Epigallocatechin 3-O-gallate 29:579,582,585,588 effects on ACE 29:579 effects on collagenase 29:582 effects on MMP (gelatinase) 29:582 effects on PEP 29:588 effects on proteasome CHYlike activity 29:585 (-)-Epigallocatechin gallate 22:319; 27:416,839 Epigallocatechin gallate 30:83 as tannin 30:83 Epigallocathechin-3-gallate 26:755 (+)-11-Epigigantenone 6:555,556 synthesis of 6:555,556 Epigloeosporone 9:241-243 synthesis of 9:241-243 7-Epigloeosporone 9:245 Epiguadalupol 6:30 from Laurencia snyderae 6:30 from perforenone 6:30 synthesis of 6:30 Epihaemanthamina 20:352 10-Epihengazole A 26:488 4-Epihenryine A 15:114,121,128,172 19R-Epiheyneanine 9:171 20-Epi-ibophyllidine 9:190,192 E(+)-I 1-piisocorynoline 14:785-787 cyclization of 14:785-788 from corysamine 14:785-787 oxidation of 14:788,789 synthesis of 14:785-787 (-)- 10-Epi-isokalihinol 25:4,856 4-Epi-isopimaric acid 15:172 Epiisopodophyllotoxin 24:762,766,771 synthesis of 24:762,766 13,14-bis-Epijeunicin 8:15,16 (+)- 10-Epijujenol 16:264 synthesis of 16:264 Epijuvabione 22:387 (-)-10-Epi-kalihinol H 25:854 (-)-lO-Epi-kalihinol I 25:856 3-EpikarounidioI 22:124
300
Epilachna varibestis 7:396; 22:398;30:333 (-)-Epilamprolobine 15:524 from Sophora tomentosa 15:524 (+)-Epilamprolobine 18:367 (+)-Epilamprolobine N-oxide 15:524 from Sophora tomentosa 15:524 7,8-Epilantolactone 10:187 Epilepsy 21:19;22:510-535,720,742 Abrus precatorius L for. 22:510 Acalyphafruticosa Forsk. for 22:510 Acorus calamus L. for 22:510 Albizzia harvey Fourn for 22:511 Allium cepa L. for 22:511 Aloe vera L. for 22:511 Alstonia scholaris R. Br. for 22:512 Alstonia venenata R. Br. for 22:512 Anagallis arvensis L. for 22:512 Annonidium monni for 22:512 Arisalema heterophyllum B. for 22:512 Arrabidaea platyphylla for 22:513 Asparagus recemosus for 22:513 Bacopa monnieri L. for 22:513 Balsamodendron sp. for 22:513 Barringtonia recemosa for 22:514 Basilicum polystachyon for 22:514 Benincasa cerifera for 22:514 Benincasa cerifera savi for 22:514 Benincasa hispida for 22:513 Bersama abyssinica for 22:514 Bombax malabaricum DC. for 22:514 Bramia monnieri L. for 22:513 Brassica nigra L. for 22:514 Butea monosperma (Lam.) Kuntze for 22:514 Canscora decussata for 22:515 Canthium gueinzii for 22:515 Cardamine pratensis L. for 22:515 Cedrus odollam for 22:516
Centipeda orbicularis for 22:516 Cinnamomum camphora for 22:516
Cissus integrifolia for 22:517 Citrus maxima for 22:517 Cocculus sermentosus for 22:517
Colchicum luteum for 22:517 Colebrookea oppositifolia for 22:517
Coleus aromaticus for 22:517 Conium maculatum L. for 22:517
Conthium guiinzii for 22:515 Cucumis colocynthis L. for 22:518
Cucumis sp. L. for 22:518 Cynodon dactylon L. for 22:518 Cyperus esculentus L. for 22:518 Cyperus rotundus L. for 22:401, 518
Daturafastuosa L.for 22:519, 742
Datura metel L. for 22:519 Daucus carota W. for 22:519 Deinbollia borbonica for 22:519 Delphinium denudatum Wall for 22:519
Dichrostachys cinerea L. for 22:519
Diospyros usmabarensis F. White for 22:520
Ekebergia senegalensis A. for 22:520
Elaeocarpus sphaericus for 22:520
Elaeocarpus tuberculantus for 22:520
Erythrina stricta for 22:520 Euphorbia nyikae Pax. for 22:520
Euphorbia tirucalli L. for 22:520 Euphorblaceae phyllantus for 22:720
Excoecaria agallocha L. for 22:520
Ferula alliacea for 22:521 Ferula galbaniflua for 22:521 Flemingia strobilifera for 22:521
301
Flueggea virosa for 22:521 Galium verum L. for 22:521 Galphimia glauca for 22:521 Gos~ypium herbaceum L. for 22:521,522
Gyrocarpus americanus Jacq. for 22:552
Helichrysum setosum for 22:522 Hemidesma indicus R. for 22:522
Herpestis monniera for 22:513, 522
Hesperethusa crenulata for 22:522
Hiptage benghalensis for 22:522 Hoslundia opposita for 22:523 Humboldtia vahliana for 22:523 Hyoscyamus niger for 22:523 Ilex aquifolium L. for 22:523 Impatiens repens for 22:523 Indigofera tinctoria L. for 22:523
lpomoea hederaceae L. for 22:523
Ipomoea hispida for 22:523 Launaea cornuta for 22:524 Leonurus cardiaca L. for 22:525 Limonia acidissima L. for 22:525
Limonia crenulata for 22:525 Lobelia inflata L. for 22:525 Maerua angolensis DC. for 22:525
Mangifera odorata L. for 22:525 Martynia annua L. for 22:526 Melissa officinalis L. for 22:526 Moghania strobilifera L. for 22:526
Moringa oleifera for 22:526 Musa paradisiaca L. for 22:526 Mylitta lapidescens for 22:527 Myrmicacin for 22:81,527 Nardostachys jatamansi DC. for 22:527 Nerium oleander L. for 22:527 Ocimum basilicum L. for 22:527 Origanum vulgare L. for 22:528 Ormocarpum kirkii for 22:528 Paeonia emodi for 22:528
Paeonia officinalis L. for 22:528 Palisota ambigua for 22:528 Paris polyphylla for 22:528 Phoenix reclinata for 22:529 Phyllanthus emblicata k. for 22:529
Phyllanthus urinaria L. for 22:529
Pongamsa glabra Vent. for 22:530
Psidium guyava L. for 22:530 Punica granatum L. for 22:530 Quercus infectoria for 22:530 Rabidaea platyphylla for 22:513 Rauwolfia serpentina L. for 22:531
Rauwolfia vomitoria L. for 22:531
Ruta graveolens L. for 22:531 Sapindus mukorossi for 22:531 Sapindus trifoliatus L. for 22:531
Saussurea lappa for 22:531 Scutellaria galericulata L. for 22:532
Semecarpus anacardium L. for 22:532
Solanum carolinense L. for 22:532
Solanum incanum L. for 22:532 Solunum xanthocarpum for 22:532
Stephania cepharantha for 22:533
Strychnos cinnamomifolia for 22:533
Synaptolepis kirkii for 22:533 Tamarix articulata for 22:533 Tamarix gallica L. for 22:533 Taxus baccata L. for 22:533 Terminalia chebula for 22:533 Trema guineensis for 22:534 Trema orientalis for 22:534 Trichosanthes anguins L. for 22:534
Valeriana hardwickii for 22:534 Valeriana officinalis L. for 22:534
Valeriana wallichii for 22:534
302
Xanthoxylon hostile for 22:535 Ximeni caffra for 22:535 Ximenia caffra for 22:535
Epileptic affections 22:517 Coleus aromaticus for 22:517 Epileptic attacks 22:526 Martynia diandra for 22:526 Epileptic children 30:377 Epileptic convulsive seizures 22:512 Annona muricata L. for 22:512 Epileptic fits 22:520,522,526,531 Elaeocarpus ganitrus for 22:520 Hiptage benghalensis for 22:522 Sapindus emarginatus L. for 22:531 Epileptic seizure 22:525 Leucas lavandulifolia for 22:525 Epilobium capense 23:404 Epilupinine 14:732-737 diastereoselectivity of 14:732737 from piperdine acetic acid 14:738 stereochemistry of 14:734 synthesis of 14:732-737 (+)-Epilupinine 16:467 synthesis of 13:483,484;16:467 Epimagnolin 18:552 from Hernandia ovigera 18:552 (+)-Epimagnolin 26:201 ;30:568, 590,595 as platelet aggregation inhibitor 30:594 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:589 (+)-Epimalyngolide 19:494 13-Epi-manool 25:252 Epimephrine 25:896 Epimerase 11:195,196 Epimeric 2,3-epoxy brassinosteroids 18:512 synthesis of 18:512 (22S,23S)-Epimeric 24-epicastasterone 18:509 Epimerization 6:558,559,367
Epi-Methyltrineracetal 30:708 structure of 30:708 (19R)-Epimisiline 5:173 (19S)-Epimisiline 5:173,174 Epimodhephene 13:39 Epimukulol 10:25-29 Epinephrine 25:516,536,538,896 L-Epinephrine 27:754 Epingaione 28:402 growth regulatory activities of 28:402 Epinodosin 15:171 from Rabdosia gaponica vat. glaucocalyx 15:171 from Rabdosia henryi 15:172 from Rabdosiajaponica 15:172 from Rabdosia sculponeata 15:174 Epinodosinol 15:172 from Rabdosiajaponica 15:172 from Rabdosia parvifolia 15:173 8-Epinonactic acid 18:235 (-)-7-Epi-nootkatone 16:239 Epipactis helleborine 30:405 (+)-20-Epipandoline 9:190 3-Epi-paraherquamide A 28:354 antihelmintic activity of 28:354 Epipedobates tricolor 19:66,146; 25:791;27:247 Epiperiplanol-13-benzoate 6:539 (+)Epiphyas postvittana 26:231 Epipinoresinol 20:620 (+)-Epipinoresinol 26:201 dimethyl ether 26:201,241 (+)-Epipinoresinol dimethyl ether 26:241 as PAF-induced inhibitor 26:241 Epipinorisenol 4'-O-glucoside 5:490, 491,494 (+)-Epiplasin-B 25:852 Epipodophyllotoxin 18:561,597-601; 26:155,210 synthesis of 18:561,597-601 4-Epipodophyllotoxin 26:193 Epipodorhizol 26:192 Epipolases kushimotoensis 25:898 Epipolasin 21:330 Epipolasin-A 21:351,354;25:853
303
Epipolasis kushimotoensis 25:853;
28:662 [3-phenylethylamine of 28:662 epipolasins A of 28:662 epipolasins B of 28:662 Epipolasis sp. 28:699 Epipolythiodioxopiperazines 25:839 Epipomolic acid (triterpene) 29:574 effects on HIV- 1 protease 29:574 14-Epipseudovincadifformine 19:105, 107 20-Epipseudovincadifformine 19:105, 107 (+)-5-Epipumiliotoxin 18:340 synthesis of 18:340 Epiquinine complexes 25:347 (+)-Epiresinol 26:268 16-Epi-rhazinaline 9:195 Epirubicin-4'-O-[3-D-glucuronide 21:175 13-Epi-sclareol 25:252;26:397 xylopyranoside 25:252 (-)-Episesamin 26:201 (+)-Episesamin 26:260 Episesartemin-B 7:219 Episesmin 26:246 (-)-6-Epislaframine 18:386 Epistatine 12:430,431 Episteganangin 26:196,216 Episterol 25:415 (-)-I-Epi-swainsonine 16:675 synthesis of 16:675 16-Epitacamine 9:179,180 Epitaondiol 17:8;25:690 (+)-5-Epitashiromine 18:345,353 22R-Epitautomycin 18:294 24-Epi-teasterone 25:422,433 12-Epi-teucvidin 601 13C-N MR data of 23:602 ~H-NMR data of 23:602 Epitheaflavic acid 28:274 formation of 28:274 Epithelial NO synthase 25:525 Epithelizing effect 26:335 Epithienamycin A,B,E,F 4:434 Epithienamycin C,D 4:434,450 7-Epithydroxylogonin 20:62
10-Epitrewiasine 70 14-Epi-triptolide 23:684 24-Epi-typhasterol 25:422,423
1-Epivalidamine 13:197,198 Epivincadine 14:634,636 synthesis of 14:634,636 Epiyangambin 26:242 as PAF-induced inhibitor 26:242 (+)-Epiyangambin 26:201 ;30:569,590, 593,595 activity in human cancer cell lines 30:589 activity in murine cancer cell lines 30:589 as platelet aggregation inhibitor 30:594 cytotoxic effect of 30:589 use of soft agar transformation assay 30:593 16-Epi-Z-isositsirikine 9:171 (+)-Epi-[3-necrodol 16:147 Epi-13-necrodol 16:153 (+)-Epi-13-santalene 16:131 Epobenzoxocin system 4:358 synthesis of 4:358 Epoformine 4:339-354,396,505 epoxidation 4:339-354,396,505 asymmetric 4:339-345 Sharpless asymmetric 4:496 stereospecific 4:505 synthesis of 4:612 Epomuricenin 17:277 Epomuricenin A 18:212,219 Epothilione 26:811 ;30:5 as microtubule stabilizing agent 30:5 Epothilone A 26:810 Epothiolones 24:406 as anti-fungal agents 24:406 Epoxidase 7:103,104 Epoxidase-epoxide hydratase system 7:107 C (2,3)-~-Epoxidation 10:39,40 ofallylic alcohols 10:39,40 Sharpless 10:39,40 with VO (acac)2-TBHP 10:39, 40 ct-Epoxidation 11:383
304 Epoxidation 11:470;16:571;24:30-32, 62,63,65,66,68,72,73,87,110-112, 175,188-190;27:753 enantioselective 16:571 hydroxy-directed 19:259 ofallylic alcohol 16:342 of cannabidiol 19:236 of enol 19:259 ofenolsilyl ether 16:332 of ketone 8:182 of limonene 16:229 of methyl perillate 6:545 of stigmasterol 16:334 of vinylsilane moiety 16:268 of c~,[3-unsaturated ketones 16:571 of c~-patchoulene 16:151 of styrene 27:753 regioselective 1:436,439 Sharpless 12:236 Sharpless asymmetric 1:278,279, 507,508,510 stereoselective 8:179-182; 16:349;19:372 with alkaline hydrogen peroxide 16:349 with t-BuOOH-KH 8:180-182 with t-BuOOH-Ti (OPr-i)4' 3:100,101 with Vo(acac)2/t-BuOOH 1:436,439 Epoxide alkylation 14:746 Epoxide hydrolase (EH) 23:476;25:150 Epoxide opening 1:439 acid catalysed 1:439 cuprate mediated 1:536 organo cuprate mediated 1:536 with cuprate 1:456,457 with dimethyl cuprate 1:523 with Redal 1:538 Epoxide rearrangement 6:136,550,551 ot-Epoxide reduction 4:418 Epoxide-furanoid rearrangement 6:162 Epoxides 1:681-684;2:4;27:79,80 generation of 27:80 oflinoleic acid 27:80 Epoxidisation system 7:105 Epoxisolancerotetrol 5:736
ent-15,16-Epoxy-9aH-labdane- 13( 16)-
14-diene 3fl,3a-diol 25:276 2,3-Epoxy alcohol 14:569 N-benzoylcarbamate from 14:569 pyrrolidine derivative from 14:570 with benzoyl isocyanate 14:569 13,~'-Epoxy alcohols 10:412 Epoxy allylic ether 10:590,591 cyclization 10:590,591 from D-ribose 10:590 synthesis of 10:589,590 Epoxy amide 12:161,162 4-benzoyloxy-b-lactam 12:161,162 from L-threonine 12:161,162 Epoxy peroxide 4:422,423 Epoxy resins 9:370 Epoxy sterol 17:22 Epoxy sulfoxide 6:310 1,2-Epoxy- 1-(2-methoxyphenyl)-2-(4methoxyphenyl)ethane 30:223 structure of 30:223 1[3,10c~-Epoxy-1,10H-desacetyllaurenobiolide 27:565 10,13-Epoxy- 11-methyloctadeca- 10,12dienoic acid 26:69 413,5[3-Epoxy- 17[3-hydroxyestran-3-one 5:449 513,6[3-Epoxy-1-oxocholist-2-ene-4[3 -ol 20:245 5[3,613-Epoxy-1a, 14(x,17[3,20tetrahydroxy-with-24-enolide 20:245 5 [3,613-Epoxy-27-hydroxy- 1,4dioxowitha-2,24-dienolide 20:234 (+)-7,8-Epoxy-2-basemen-6-one 16:226 Epoxy-3 [3,4a, 10a-trihydroxyguaian6or, 12-olide 27:579 1[3,10o~-Epoxy-3[3-hydroxy-7o~,11(xHgermacra-4Z-en- 12,613-olide 27:563 2~,5-Epoxy-5,10-dihydroxy-6~angeloy-loxy-913-isobutyloxygermacran-8c~, 12-olide 29:89 activity in iNOS assay system 29:89
305 activity in NFkB assay system 29:89 7c~,8ot-Epoxy- 6 c~-hydroxyabieta9(11), 13-dien- 12-one 29:99 activity in EBV assay system 29:99 3,4-8c~-Epoxy-8-deoxycumambrin 27:577 9,10a-Epoxy-9,10-seco-abieta-8,11,13trien-18-oic acid 29:99 activity in EBV 29:99 (20( R),24)S- Epo xy-9fl, 19-cyc lo lanostan3fl,16fl-25,tetrol 25:217 Ent-8a,14c~-Epoxyabiea- 11,13(15)dien- 16,12-olide (jolkinolide A) 9:283,284,290 ?,6-Epoxyacrylate 21:412 19R,20S- 19,20-Epoxyakuammicine (stictine) 9:192 ot,13-Epoxy-aldehyde 30:473 synthesis of 30:473 Epoxyaldehydes 27:82 generation of 27:82 hydrolysis products of 27:82 cis-c~,f3-Epoxyaldehydes 30:473 Epoxyalkyl glycosides 7:39 4 '(R )-3 '-Epoxyangeloyloxy-4 '-acetoxy3'-4'-dihydroseselin 27:429 19R-20R-Epoxy-apparicine (apparicine) 9:172,173 9a,11 a-Epoxycholest-7-ene 313,5c~,6f3tetrol-6-acetate 5:410 19',20'-Epoxy-conoduramine 5:128 (20(S),24)R-(Epoxycycloartane) 25:227 20,24-Epoxycycloartane derivatives 27:449 1c~,1013-Epoxydeacetyl laurenobiolide 27:564 3,4-Epoxydehydroleucodin 29:90 activity in NFkB assay system 29:90 Epoxydibenzocyclooctene 30:226 Epoxydihydroartemisitene 22:161 15 [3,20[3-Epoxydihydrocatharanthine 14:811,871,872 leurosine from 14:811,871,872 N-oxide derivative of 14:811 with vindoline 14:811,871,872
Epoxydilactone 17:608 Epoxydon 4:612 synthesis of 4:612 2,3-Epoxyeleganolone 18:713 or, [3-Epoxyenone 14:678-681 l[3,2f3-Epoxy-enone intermediate 5:447 3,20-Epoxy-ent-kaurenes 15:136 24,28-Epoxyergost- 5-ene- 3 [3,7ct-diol 20:476,477 Epoxyfatty acid 23:341 Epoxyflabellin 27:578 (7S)-4~3,5a-Epoxygermacr- 1( 10)E-en213,613-diol 29:88 activity in PLA assay system 29:88 activity in TPA assay system 29:88 Epoxyguaianolide 14:362 16,23-Epoxyhalosta-7,24-dien-3 ~-ol 7:277 Epoxyindenone 1:189 Epoxyjaeschkeanadiol 5:724,725,731, 732,735 Epoxyketone 15:167 Epoxyketonucleosides 4:248 synthesis of 4:248 8,13-Epoxy-labd-14-en-oic acid 25:249 (E)-8 [3,17-Epoxylabol- 12-ene- 15,16-dial 23:798 Epoxylactone 17:10 6,7-Epoxy-Lat A 25:874 6,7-Epoxylinalool 25:141 Epoxylobatrenol 21:276 (S)- 1,2-Epoxylycopene 20:593 1,2-Epoxylycopene 20:593 413,15-Epoxymiller-9E-nolide 29:89 activity in NFkB assay system 29:89 activity in TNFc~ assay system 29:89 4[3,15-Epoxymiller-9Z-enolide 29:89 activity in NFkB assay system 29:89 Epoxy-nucleosides 4:225 Epoxypironetin 30:27,28 as mitotic arrester 30:27 effect on G2/M phase 30:28 structure of 30:28
306
7,20-Epoxyroyleanone 20:670 Epoxysantamarine 27:556 1,2-Epoxy-S-carotene 20:593 Epoxysesquipellandrene 8:58 synthesis of 8:58 Epoxyshikoccin 15:163-165,174 22,23-Epoxysteroids 15:48 24,25-Epoxywithanolide D 20:246 6 [3,7[3-Epoxywithanone 20:204 7,8-Epoxyzahavin A 29:103 activity in AOS bioassay system 29:103 Epoxy-13-carotenes 30:840 EPR Spectroscopy 25:340 Epstein-Barr virus (EBV) 10:4;12:234, 390,395 ;22:616;24:215,849;25:45; 30:394,592 in raji cells (EBV genomecarrying human lymphoblastoid cells) 30:592 Epstein-Barr virus early antigen 21:642; 24:215-217;25:46;30:592 activation inhibition of 30:592 inhibition of 25:46 Epstein-Barr virus inhibition 30:560 due to lignans 30:560 due to isoquinoline alkaloids 30:560 Equatorial side-chain 27:341 Equisetin 28:121 antibiotic activity of 28:121 cytotoxicity of 28:121 HIV inhibitory activity of 28:121 ER ryanodine receptor Ca2+ channels 25:517 Eragrostis curvula 26:469 pyrocathecol from 26:469 Erbstatin 15:441 Ercalcidiol (25-hydroxyvitamin D2) 11:381 Ercalcitriol (1 c~,25-hydroxy vitamin D2) 11:381 Eremane diterpenes 15:271-274 (-)-Eremanthin 14:368 Eremanths elegnus 24:6 Eremanthus glomerulatus 7:427 Eremanthus mattogrossensis 29:90
Eremmophla aureonontata 5:223,225,253 Eremoacetal 15:238 Eremofrullanolide 2:280,281 (+)-Eremolactone 15:252,271 synthesis of 8:425 from Eremophilafreelingii 15:252,271 from Eremophilafraseri 15:252,271 synthesis of 15:272 Eremophila 15:225-282 Eremophila abietina 15:227 Eremophila alternifolia 15:225,232 Eremophila caerulea 15:227,281 (+)-fenchone from 15:227 oleanolic acid from 15:281 ursolic acid from 15:281 Eremophila clarkei 15:253 Eremophila cuneifolia 15:227,248 Eremophila dalyana 15:225,227 Eremophila decipiens 15:263 Eremophila dempsteri 15:227,254 Eremophila drummondii 15:244,248 (+)-calamenene from 15:244 serrulatane from 15:259 (+)-spathulenol from 15:248 Eremophila duttonii 15:225 Eremophila elderi 15:225 Eremophila exilifolia 15:252 Eremophilafoliosissima 15:255 Eremophilafraserii 15:248,252,271 Eremophilafreelingii 15:252,271 eremolactone from 15:252,271 freelingyne from 15:233 Eremophila georgei 15:269,271 Eremophila gilessi 15:225 Eremophila glutinosa 15:252 Eremophila granitica 15:254 Eremophila inflate 15:229 Eremophila interstans 15:245,247 Eremophila latrobei 15:229,232,258 biflorin from 15:258 Eremophila longifolia 15:225 Eremophila maculata 15:226,229 Eremophila miniata 15:229 Eremophila mitchelli 15:226,281 Eremophila paisley 15:248 Eremophila petrophila 15:252
307
Eremophila platycalyx 15:281 Eremophila racemosa 15:248 (+)-spathulenol from 15:248
Eremophila rotundifolia 15:233 freelingyne from 15:233
Eremophila scoparia 15:227,232,244 Eremophila serrulata 15:257,259 Eremophila spp. 8:423 (+)-isoeremolactone from 8:423
Eremophila virgata 15:245 Eremophila viscida 15:260
Eremophilane sesquiterpenes 6:554-556 Eremophilanes 7:214,216,152,227,243 Eremophilane-type sesquiterpene 18:639 Eremophilanolide 20:660 7-epi-Eremophilene 15:250 Eremophilone 10:436,437 Claisen rearrangement by 10:436,437 from Eremophila mirchelli 15:238 synthesis of 10:436,437;15:243 stereoselective synthesis of 15:240 Ergine 25:531 Ergocalciferol (vitamin D2) 9:510,521 Ergoclavine 21:91 Ergocornine 21:68 r 4:605,606 synthesis of 4:605,606 Ergolide 29:90 activity in COX assay system 29:90 activity in NFkB assay system 29:90 activity in iNOS assay system 29:90 Ergoline alkaloids 25:706 Ergometrine 21:68,91,96,98,102,109 Ergonovine 13:631;21:488 from Clavicieps purpurea 13:631 Ergosine 21:68 Ergost-5,24 (28)-diene-313,7c~-diol 20:476,477 Ergost-5-en-1 c~,313-diol 11:381
Ergo st-5 -ene- 313,7r tetrao 1 20:476 Ergosta-5,24 (28)-diene-3 [3,713-diol 20:477 Ergostane 16:332;25:49,61 Ergosterin (ergosterol) 9:509,510 Ergosterol 5:406,261,322,509;9:447; 22:59;28:570,572 ;30:489,506,508 as antitumor substance 28:570 effect on neovacularization 28:572 from lanosterol 30:506 ozonolysis of 30:489 Ergosterol biosynthesis 30:485 Ergosterol derivative 30:506 22,23-dihydroergosterol (provitamin D4) as 30:506
24-epi-22,2 3-dihydroergosterol
as 30:506 Ergosterol esters 9:456 Ergosterol mesylate 18:509 Ergosterol mutants 25:304 of Nenrasapora crassa 25:304 Ergosterol peroxide 25:61 Ergosterol-5,8-peroxide 7:218 from Artemisiafeddei 7:218 Ergot 21:91 Ergot alkaloids 11:199-207; 21:57,68,91 ;22:247 biosynthesis of 11:199-207 Ergotamine 13:631 ;21:68,91, 488;25:531 Ergothioneine 25:813 Ergovaline 21:68 Ergoxanthine 20:282 Eria ravanica 23:522 Erica andevalensis 22:428;25:612 myricetin-3-O-D-galactoside from 22:428 Ericaceae 25:246 Erigeron philadelphicus 26:436 Eriobotryajaponica 17:115,118-119; 19:247 Eriocalxin A,B 15:176 Eriocitrin 23:747;26:744;29:579 effects on ACE 29:579 Eriodictyol 30:286 13C-NMR data of 30:286
308 Eriodictyol-3',4'-dimethylether 30:746 structure of 30:746 Eriodyctiol 22:351;26:757 Eriosema compound B (prenylated xanthone) 29:579,581 effects on ACE 29:579 effects on NEP 29:581 Eriosema tuberosum 29:579 Erithrodiol 20:705 Erithrodiol-28-acetate 20:707 Erivanin 7:232;27:51 3-epi-Ervafolidene 5:129 Ervafolidine 5:129 Ervafoline 5:129,172 Ervahanine 5:123 Ervahanine C 5:129 Ervatamia coronaria 5:135,136, 158,171,172 Ervatamine 5:125 20-epi-Ervatamine 5:127 Ervatamine-type alkaloids 5:80-82 19,20-dehyroervatamine 5:81 ervatamine 5:80-82 20-epi-ervatamine 5:81 isomethuenine 5:81 methuenine 5:81 methuenine-Na-oxide 5:81 6-oxo-methuenine 5:81 silicine 5:81 6-oxo-16-epi-silicine 5:81 20-epi-silicine 5:81 iso-6-oxo-silicine 5:81 Ervaticine 5:87,88,124,135,136 Ervima coli 25:220,258,259,394, 450,821,928 Ervincidine 13:393 Ervinidinine 9:190 Ervitsine 5:126 Ervitsine-type alkaloids 5:81,82 Erwinia 4:434 Erwinia amylovra 25:394 Erwinia carotovora 25:394 Erwinia chrysanthemi 25:394 Erwinia herbicola 17:637 Erybidine 6:478 synthesis of 6:478 Erycibe elliptilimba 21:751 Erycibe obtusifolia 21:751 baogongteng A from 21:750
Erylus formosus 26:80,85 Eryocalyxin A 15:171 Eryocalyxin B 15:171 from Rabdosia eriocalyx 15:171 from Rabdosia eriocalyx var. laxiflora 15:171 Erysodienone 3:468 synthesis of 3:468 Erysodine 3:455;21:52 Erysotinone 3:478 Erysotramidine 3:471-476 synthesis of 3:471-476 Erysotrine 3:470,474,475 synthesis of 3:470,474,475 Erytharbine 3:476 synthesis of 3:476 Erythema infectiosum 30:394 Erythraline 3:474 synthesis of 3:474 Erythramine 3:455 Erythratidine 3:455 Erythratidinone 3:455 Erythrina 3:455-493 Erythrina abyssinica 29:781 Erythrina arborescens 3:455-493 Erythrina berteroana 7:417 Erythrina burana 20:496 Erythrina caffra 29:604 Erythrina crysta-galli L. 3:476 Erythrina ETI-a ETI-b 29:604 Erythrina isoquinoline alkaloids 25:528 dehydro-fl-erythroidine 25:528 erysinine 25:528 erysotrine 25:528 erythratidine 25:528 a-erythroidine 25:528 fl-erythroidine 25:528 Erythrina latissima 29:604 Erythrina lithosperma 3:479 Erythrina melinoniana 22:27 Erythrina stricta 22:520 for epilepsy 22:520 Erythrina type 11:229 Erythrina variegata L. 22:520; 29:598,604 Erythrinan-3-one 6:477,478 Erythrinane skeleton 1:327 synthesis of 1:327
309
Erythrinin B 28:229 biological activity of 28:229 D-Erythritol 6:357,358 Erythritol 9:288 Erythro compounds 12:415,416 (15S,16S)-Erythro diasteromer of pumiliotoxin B 12:294 Erythro ethyl [3-hydroxy-[3-(2- piperidyl) propanoate 12:279 Erythro-2-amino alcohols 12:430,431 Erythrodiol 22:126;25:57,60,64;29:586 effects on LELA 29:586 Erythro-glycal 10:341 D-Erythro-hexofuranose 6:376 [3-Erythroidine 3:455-456 Erythroidine alkaloids 3:487,488 synthesis of 3:487,488 Erythro-monopivaloate 23:188 Erythromycin 5:613 Erythromycin A 11:196,197;22:265 biological activity of 12:48 from (9S)-9-dihydroerythronolide A 12:53,54 total synthesis of 12:53,54 X-ray crystal studies of 13:156 Erythromycin A aglycone 3:233 Erythromycin B 11:196,197 Erythromycin-9-oxime 13:160,161 Beckmann rearrangement of 13:160,161 Erythromycylamine 13:170,171 Erythronolide 13:155,156 Erythronolide A 3:233-278,280 synthesis of 11:152,153,157 Erythronolide A enol ether 13:165 Erythronolide A seco-acid 11:154-156 synthesis of 11:154-156 Erythronolide B 16:660-661 by dioxanone-to-dihydropyrane enolate Claisen rearrangement 10:340 seco acid of 16:660 synthesis of 3:278-280;16:660661 D-Erythropentofuranose 6:365,366 D-Erythropentose 6:360,463,364 Erythropoietic protoporphyria 30:524 use of[3-carotene 30:524
Erythropoietin (EPO) 29:547 antibodies against 29:547 as hormone 29:547 in red blood cells production 29:547 inhibition of 29:548 oxidation of 29:547 periodate oxidation of 29:548 reaction with lectins 29:548 reaction with serum 29:548 recombinant type of 29:547 structure of 29:547 Erythrose 4-phosphate (E4P) 23:83,741 Erythroskyrine 21:413 D-(+)-Erythro-sphingosine 192 L-(-)-Erythro-sphingosine 192 Erythroxanthin sulphate 30:526,527 structure of 30:527 Erythroxylaceae 22:718,720 Erythroxylon 21:488 Erythroxylon monogynum 10:180 Erythroxylum spp. 22:520,718,721 D-Erythro-[3-methylaspartic acid 9:496 Esbericum 22:698 Escallonia spp. 29:572 Eschenmoser reaction 8:211 Eschenmoser ring contraction 9:601,602 Eschenmoser-Claisen rearrangement 10:417,419-421,427,428 Eschenmoser's salt 4:665,10:164,19:94 Escherichia chrysanthemi 25:394 Escherichia coli 4:433;5:367,429,434; 7:39,44,46,50,52,54 ;9:293,308,537,5 92,593,596,603,604,606;8:102;11:18 2,214;12:63,95-109;13:157,162,164, 261,262,283;17:378;18:709,722,727, 921 ;19:601 ;20:712;21:174,175,299, 573,600;22:623,627;23:67,137,235, 474,533;24:713;25:257,319,765,775, 925,948;26:330,331,333,402,556, 605,802,1092,1093,1135,1263,1269, 1271,1272,1274,1278;27:305; 28:519;30:739,843 antibacterial activity against 30:739 antifungal activity against 30:739 biological activity of 30:843
310
Escherichia coli BFI-ATPase 10:439 Escherichia faecilis 25:259 Eschscholtzia 27:163 Eschscholtzia californica 27:159 Eschweiler-Clarke methylation 10:84, 165 Eschweiler-Clarke reaction 1:203, 384,385 Escins (triterpene saponin) 29:574 effects on HIV- 1 protease 29:574 Escobedria scabrifolia 30:528 azafrin from 30:528 Esculetin 5:515,517,521,579;22:168; 23:356;26:314,315,317,318,330-334, 336-340,342,344 Esculin 5:515,521;26:317,318,330-342 Eseramine 21:84;25:536 as immunosuppressive drug 25:536 Eserethole 1:326 synthesis of 1:326 (-)-Eserethole 14:637,638 (-)-physostigmine from 14:637,638 synthesis of 14:636-638 Eseridine 25:536 as immunosuppressive drug 25:536 Eserine 21:84,753 (-)-Esermethole 14:639 synthesis of 14:639 (-)-Estafiatin 14:358,359 ESP 21:555 Esperamycin 10:150,153 Espintanol 26:797,798,807 Espulegol 23:342 Essential oil 21:596;24:232;28:412,415, 427,390,408,421,426;30:605,607 acaricidal activity of 28:412,427 against sarcoptic mange 28:415 antimicrobial activity of 21:235 from limonene 30:607 from nonane 30:607 from c~-gurjunene 30:607 from a-pinene 30:607 from ~-pinene 30:607 lethality tests of 28:392
of hypericum 30:605 use as bactericides 28:390 use as fungicides 28:390 use as insecticides 28:390 Estafiatin 1:546,558,235 Esteinascidin 25:825 Ester enolate Claisen rearrangement. 3:236,246,259,261-265,267-270, 274-276,278-280;14:497 Ester epimerization 1:466 Ester exchange reaction 4:519 Ester type glycoside linkage 7:154,155 Esterase 13:303 Esterification 4:91,92,276,292,391,409, 412,413 Estogen-sensitive tissues 5:447 Estradiol 3:435;6:222 synthesis of 3:435 fluorinated derivatives of 5:451 Estragole 13:335;1:600 Estreogen 5:477,499,456;17:625-526 Estrogen 2-hydroxylases 5:449 Estrogen agonist/antagonist properties 26:210 secoisolariciresinol diglycoside 26:210 Estrogen hormones 9:411 Estrogen responsive kidney 5:447 Estrogenic activity 21:759;23:353 of coumarin 23:335,356,357, 353,368,376,393,550,553; 26:760 Estrogen-like activity 28:227 of phenols from moraceous plants 28:227 of Glycyrrhiza species 28:227 Estrogen-receptor antagonists 25:797 Estrone 4:501,502 asymmetric synthesis of 4:501,502 synthesis of 3:435 (-)-Estrone 4:675 (+)-Estrone 7:6 Et 722 25:826 Et 743 N 12oxide 25:825,827 Et's 25:595,581,592,826 Eteromorpha prolifera 25:691 Ethambutol 2:424,20:714 1,2-Ethanedithiol 11:357
311
Ethanoflurene 6:175 Ethanol 25:966 LTP-blocking effect of 25:966 [3H]-Ethanolamine 25:342 Ethanolamine 5:299 Ethanophenanthrene 6:173,174 5 5,10[3-Ethanophenanthridine nucleus 4:4 S,S'-l,2-Ethendiyl O,O'-diisobutyl 25:898 Etherification 4:718-720 Ethionamide 2:424 Ethisolide 3:261,19:485 Ethnoarcheological studies 13:630 Ethnomedical uses 23:652 of celastraceae 23:652 Ethnopharmacology 13:640 3-Ethoxcarbonyl-2-benzylideneproanoic acid 22:295 3-[cz-Ethoxy(ct-methyl-thio)]methyl-2thionopyrolidine 26:1083 5c~-Ethoxy-4,5-dihydrojabarosalactone B 20:223 a-Ethoxyacrylonitrile 30:449 photolysis of 30:449 3-Ethoxycarbonyl pyrrolidinone 13:131,132 2-(Ethoxycarbonyl)-tryptamine 19:89 19-Ethoxycarbonyl- 19-demethylvincadifformine 19:112,115 Ethoxycarbonylation 6:541 MIN-([3-Ethoxycarbonylethyl)-5oxopyrrolidine-2-carboxylate 12:308 Ethoxycarbonylmethylene (triphenyl) phosphorane 12:315;21:416 (3-Ethoxycarbonylpropyl) triphenylphosphoniumbromide 12:318 3-Ethoxycarbonylpyrrol- 2(5H)-ones 13:131,132 3-Ethoxy-coronaridine 5:126 bis-Ethoxyethyl olivetol 19:225 13-Ethoxylabda-8(17), 11,14-trien- 19oic acid N-(methyl)phthalamide 29:101 activity in EBV bioassay system 29:101 [3-Ethoxypropiophenone 14:648
1-Ethoxyvinyl lithium 30:458 reaction with 30:458 ozonolysis of 30:458 Ethoxyvinyllithium 30:458 as reagents 30:458 Ethyl (1R,2S)-5,5-ethyienedioxy-2hydroxycyclohexane- 1-carboxylate 6:552,553 Ethyl (2E,4E)- 12-hydroxy-2,4dodecadienoate 10:152 Ethyl (S)-lactate 12:161 Ethyl 1,6-dithiogentiobioside 8:341 synthesis of 8:341 Ethyl 2-(bromomethyl)-acrylate 30:451 nucleophilic addition of 30:451 Ethyl 2-[ 1-(2-ethoxycarbonylmethyl) piperidinyl]-propanoate 12:284 Ethyl 2-diazoacetate 30:446 reaction with 30:446 Ethyl 2-methoxy-6-methyl benzoate 9:346,347 synthesis of 9:346,347 Ethyl 3-(S)-hydroxybutyrate 6:263 Ethyl 3-hydroxybutanoate 1:689, 690,707 (S)-Ethyl 3-hydroxybutyrate 4:439, 440,448,449,452,453,455,464 Ethyl 4-[ 1-(2-ethoxycarbonylpyrrolidinyl)] butyrate 12:293 Dieckmann condensation of 12:293 Ethyl 8'-apo-f3-caroten-8'-oate 20:606 Ethyl benzamalonate 9:224 Ethyl benzimidates 22:292 Ethyl catechol 25:925-927 Ethyl diazoacetate 14:402 Ethyl fructofuranoside 8:324,325 (S)-Ethyl lactate 8:133,136 Ethyl malonyl CoA 11:194 Ethyl phenylpropiolate (EPP) induced edema 25:46 (+)-Ethyl picolate 12:279 Ethyl sorbate 8:410,414,148,149 24-Ethyl thomasterol A 15:48 Ethyl ~-bromocrotonate 8:418,419 Ethyl ~-trifluoroacetoxy acrylate 30:450
312 radical conditions 30:450 reaction with 30:450 Ethyl [3-apo-8'-carotenate 20:756 Ethyl-2-(diethoxyphosphonyl) propinoate 20:595 24-Ethyl-24,28-methylene-cholesterol 9:36,37 24-Ethyl-26-hydroxysteroids 15:84 2-Ethyl-2-hydroxyindolizidine 12:284 2-Ethyl-2-propen- 1-ol 14:828 (2S,3S)-2-Ethyl-3,4-isopropylidenedioxy-propan-l-ol 30:39 from L-malic acid 30:39 role in (-)-pironetin synthesis 30:39 2-Ethyl-3-vinylcyclopentanone enolate 8:192,193 9-Ethyl-4-hydroxy-3-hydroxy-methyl1,7-dio xasp iro-[ 5.5 ]-undec ane 14:531 1-Ethyl-4-methylsulfone-fl-carboline 25:819 2-Ethyl-5-heptyl- 1-nitrosopyrrolidine 6:439,440 synthesis of 6:439,440 3-Ethyl-5-methylindolizidine 6:450 2-Ethyl-5-pentylpyrrolidine 6:437,444 7-Ethyl-7-hydroxyindolizidine 12:286 3-Ethyl-allohobartine 11:318,319 24-Ethylbrassinone 18:500 5 '-N- Ethylc arb oxamidoadeno sine 27:878 (24S)-24-Ethylcholest-5,22-dien-313-01 (stigmasterol) 9:447 (24R)-24-Ethylcholest- 5-en-3 [3-ol (sitosterol) 9:447 (+)-3-Ethylcompactin 11:371 O-Ethylcryptaustoline iodide 6:482 (-)-N-Ethylcytisine 15:525 from Echinosophora koreensis 15:525 Ethyldeoxynojirimycin 10:527,528 NEthylene biosynthesis 25:657 Ethylene diamine tetraacetic acid (EDTA) 21:540;30:844 Ethylenediamine tetraacetic acid 21:540 N-Ethylene-methylketone 21:265,266
3-Ethylidene- 1,3-dihydro-indol-2-one 9:236,237 24-Ethylidenecholesterol 20:234 4,6- O-Ethylidene-N-benzoyl-Dglucosamine 18:462 Ethyllithium 14:510 Ethylmalonic acid 13:76 Ethylmaltol 22:540,528 Ethylphenyl acetate 6:323 2-Ethylpropane-l,3 diols 13:88-93 2-Ethylpropanol 14:840,841 7-O-Ethylrosmanol (abietane diterpene) 29:575 effects on HIV- 1 protease 29:575 synthesis from carnosolic acid 29:575 Ethyltetradecatrienoate 23:191 q 5-Ethyltetramethylcyclopentadienyl-dig-thiocynato rhodium complexes 21:222 Ethylurethanes 6:427,428 Ethylvinyl ketone 6:19 Etlatol 25:787 EtN 12oxide 25:826 Etopophosphate 26:160 Etoposide 5:461,462,13:364,365,654, 20:458;21:136,160;26:160-163,171, 172,212,21 -~ cytotoxiclty of 26:213 use in combination therapy 26:171 Etoposide phosphatase 21:160 Etoposide phosphate 26:160 in lymphoid cancer 26:171 in myeloid leukemia 26:171 in refractory testicular cancer 26:171 m stomach cancer 26:171 m ovarian cancer 26:171 m brain cancer 26:171 m breast cancer 26:171 in pancreatic cancer 26:171 m small/non-small lung cancer 26:171 Etzionin 10:247 Etzionine 240 Eu (fod)3-mediated 4:121,122,143 [4+2] cycloaddition 4:121,
313 122,143 Diels-Alder reaction 4:121,122 Eu (fod)3-mediated [4+2] cycloaddition 4:121,122,143 Diels-Alder reaction 4:121,122 Eu (hfc)3 4:326 Eubacterium saburreum 4:195 Eucalbanin B 23:405 Eucalbanin C 23:405,414 Eucalyptol 13:337 Eucalyptus 27:755;29:589 Eucalptus citriodora 25:32 Eucalyptus alba 23:405,413 Eucalyptus amplifolia 24:234;29:111 Eucalyptus blakelyi 24:234;29:111 activity in EBV bioassay system 29:111 from Euglobal-BI-1 29:111 Eucalyptus calophylla 19:247 Eucalyptus camaldulensis 28:427 acaricidal activity of 28:427 Eucalyptus globulus 24:232;28:402 Eucalyptus grandis 24:234,240; 26:445;29:111 Eucalyptus grandis 29:111 activity in EBV bioassay system 29:111 activity in EBV, lung-2, skin-l, skin-3 bioassay systems 29:111 activity in lung-2 bioassay system 29:111 activity in skin-1 bioassay system 29:111 activity in skin-3 bioassay system 29:111 euglobals from 29:111 Eucalyptus haemastoma 26:696 Eucalyptus incrassata 24:234 Eucalyptus marinata 19:247 Eucalyptus polybractea 24:232 Eucalyptus robusta 23:405 Eucalyptus' smithii 24:232 Eucalyptus sp. 21:526,527;29:83 Eucalyptus spathulata 15:248 (+)-spathulenol from 15:248 Eucaryote signals-regulated protein kinase (PK's) 25:521,522 (2S)-Euchrenone 28:17 as aromatase inhibitor 28:17
Euchresta formosana 29:781 Euclabanins 23:407 Euclea natalensis 30:328 isodiospyrin from 30:328 Eucommia ulmoides 5:505,521525,530,544 ;20:613,647-648;26:235 (+)-pinoresinol diglucoside from 26:235 Eucommiol 7:441,442,472-474 Eucryphin 27:395 Eudesm-11-en-4-ols 14:451 from Amitermes excellens 14:451 from Artemisia schmidtiana 14:450 from Bothriochloa bladhi 14:450 from Bothriochloa glabra 14:450 from Bothriochloa intermedia 14:449 from Bothriochloa insculpta 14:450 from Carthamus lanatus 14:450 from Citrus paradisi swingle 14:450 from Cymbopogon flexuosus 14:450 from Euginia uniflora 14:450 from Geigeria burkei 14:450 from Humulus lupulus 14:450 fromMyrica gale 14:450 from Pisidium guajava 14:450 from Podocarpus dacrydioides 14:450 from Riccardia jackii 14:450 from secretion of termite soldier 14:451 from Senecio amplexicaulus 14:450 from Subulitermes bailey 14:451 from Subulitermes oculatissimus 14:451 from Subulitermes parvellus sp. A+B 14:451 from Velocitermes velox 14:451 7-epi-Eudesm-4( 15)-ene- 1[3,6~-diol 21:584;23:635 Eudesmaafraglaucolide 7:232 Eudesman-12,6-olides 7:212,231-233
314
Eudesmane alcohol 14:456-465 from (-)-c~-santonin 14:456-465 synthesis of 14:456-465 Eudesmane sesquiterpenes 2:280 Eudesmanes 7:208,214,168,181,187; 25:848,849 activity in EBV bioassay system 29:87 1,2,6,8,15-pentaacetoxy-9benzoyloxy-4-hydroxy-dihydro[3-agarofuran as 29:88 1c~,2c~,15-triacetoxy-6[3,9[3difuroyloxy-4 ~-hydroxydihydro-[3-agarofuran as 29:88 1c~-acetoxy-2 ot-benzoyloxy6[3,9~3-difuroyloxy-4[3-dehydro13-agarofuran as 29:87 1c~-acetoxy-6a,9[3-difuroyloxy2a-( 2-methylbutyroyloxy)-4 [3hydro xy-dihydro- [3-agarofuran as 29:88 1c~-acetoxy-6~3,913-difuroyloxy2a,4[3-dihydroxy-dihydro-[3agarofuran as 29:87 1c~-acetoxy-6[3,913-difuroyloxy2c~-propyonyloxy-4 [3-hydroxydihydro-[3-agarofuran as 29:88 eumaytenol as 29:88 euonymine as 29:88 from Wieland-Miescher ketone 6:18,19 synthesis of 6:18,19 2,3-seco-Eudesmanes 7:216 4,5-seco-Eudesmanolide 7:215 6fl-Eudesmanolides 24:72,73 Eudesmanolides 6:18,19;24:56,806 from Wieland-Miescher ketone 6:18,19 synthesis of 6:18 Eudesmin 24:755;26:268 synthesis of 24:755 (-)-Eudesmin 26:200 (+)-ot-Eudesmol 14:406-413 synthesis of 14:406-413 (+)-13-Eudesmol 14:490;21:584 synthesis of 1:632;14:490
via asymmetric cyclopropanation 14:490 [3-Eudesmol 15:243,244;23:811 neointermedeol from 14:453,454 ozonolysis of 14:453,454 ElO-epi-~[-udesmol 21:583,584 7-epi-cz-Eudesmol 21:583,584 ot-Eudesmol 21:583,584 lO-epi-~/-Eudesmol 23:811 [3-Eudesmol 21:583,584;29:87 activity in AM assay system 29:87 Eudesnols 21:583,584,585 Eudestomins 8:274 Eudistoidin E and F 25:818 Eudistoma 19:660 Eudistoma album 23:263 Eudistoma cf. rigida 10:247;28:635 iejimalide C from 28:635 iejimalide D from 28:635 Eudistoma divaceum 25:902 Eudistoma fragum 23:257 Eudistoma gilboverde 28:634 methyleudistomidin C from 28:634 Eudistoma glaucus 5:353;23:262,263; 25:758,817;28:634 eudistomidin C from 28:634 Eudistoma olivaceum 5:100,417,418, 246;21:260,321 ;25:816;28:633 [3-carboline alkaloids from 28:633 eudistomins from 21:260 N(10)-methyleudistomin E from 28:633 Eudistoma sp. 12:366,370;10:247; 25:820,834 ;28:637 desmethylvaracin from 28:637 Eudistoma taoelensis 21:260 N-demethyl staurosporine from 21:264 3-hydroxy staurosporine from 21:264 staurosporine from 21:254,264 Eudistomidin A 23:261 ;5:758 Eudistomidin B 25:759 Eudistomidin C 25:758 Eudistomidin D 25:758,759
315 Eudistomidin F 25:863 Eudistomin A 5:418;23:261 Eudistomin C 5:417,418;25:782 Eudistomin D 5:418;23:261 Eudistomin E 5:417,418;25:782 Eudistomin F 5:418 Eudistomin G 5:418;23:261 Eudistomin H 5:418;23:261 Eudistomin I 5:418;23:261 Eudistomin J 5:418;23:261 Eudistomin K 5:418;23:261 Eudistomin K sulfoxide 25:863 Eudistomin L 5:417-418 Eudistomin M 5:418;23:261 Eudistomin N 5:418;23:261 Eudistomin O 5:418;23:261 Eudistomin P 5:418;23:261 Eudistomin Q 5:418;23:261 Eudistomin R 5:418 Eudistomin S 5:418 Eudistomin sulphide 25:816,817 Eudistomin T 5:418 Eudistomins 23:233,262,268;25:782, 815,817 occurrance of 23:265 oxathiazepine ring of 23:265 Eudistomins A-Q, S,T 10:246,247 Eudistomins C,E,F and L 25:816,817 Eudistomins D,J,N and O 25:782 Eudistomins H&I 21:321 Eudynamis scolopacea 5:837 Eugenia 21:600;27:755 Eugenia caryophyllata 21:585 Eugenia uniflora 14:450;23:405 Eugeniflorin D1 23:405,410 Eugeniflorin D2 23:418 Eugenol 5:473,474;21:572,586,594, 595,600,602,613 ;25:126;28:403 acaricidal activity of 28:403 as bioactive monoterpenoid 28:426 Euglena gracilis 23:124;26:363;30:397 (1-3)-~-D-glucan from 30:397 Euglena viridis 6:150 Euglenophyta 27:735 Euglenopyceae 6:134,147,150,151 Euglobals 29:111 activity in EBV bioassay system 29:111
Euhypericum 30:610 hypericin from 30:609 Eukaryate signal transduction 25:512 components 25:512 inhibition of 25:512 Eukaryotes 22:57;23:14 Eukaryotic genes 4:268 Eukaryots 27:736 Eumelanins 26:1018 Eumenes fraternus 5:224,225,232,253 Eumycota 9:202 Eunicea 10:9 Eunicea fusca 21:276;29:690 Eunicea succinea 26:83 Eunicea taurneforti 20:492;25:690 Eunicella cavolinii 25:690 Eunicia succinea 10:7 Euniolide 10:7 Euodynrus fuscus 5:224,253 Euoniminol 18:747 Euonomynus 18:741 Euonymine 29:88 activity in EBV assay system 29:88 Euonyminol 23:663,674 (+)-Euonyminol 23:664 Euonymus 18:753 Euonymus alatus 23:655 Euonymus atropurpureus 23:655 Euonymus bungeanus 23:668 antifeedant sesquiterpenes from 23:668 insecticidal sesquiterpenes from 23:668 Euonymus europaeas 23:655,674 Euonymus fortunei 23:668 Euonymus tingens 30:668 tingenone from 30:668 Euonymus verrucosus 23:656 Eupafolin 7:226 Eupatilin 20:712 from Salvia limbata 20:712 from Salvia nemorosa 20:712 Eupatin 7:227 Eupatorenone 5:28-30;7:275,276 Eupatorium adenophorum 5:28 Eupatorium articulatum 22:353 Eupatorium fortunei 24:273 Eupatorium gracile 29:573
316
Eupatorium maculatum 20:145 Eupatorium quadrangulare 24:103 Eupatorium trapezoideum 15:247 Eupatorsum inulaefolium 22:349 5,6,3 '-trihydroxy-7,4 '- dimethyoxyflavone pedalitin from 22:349 Eupatrin 30:726,727 structure of 30:726 Eupentactafraudatrix 7:275,276; 21:314;28:598 from calcigeroside B 28:598 from calcigeroside CI 28:598 from calcigeroside DI 28:598 from cucumarioside G2 28:598 Euphane 25:50 Euphanes (tirucallanes) 9:267,297, 302,307 (-)-Euphococcine 16:481 synthesis of 16:481 Euphol 25:61 Euphorabia characias 26:1263,1277 Euphorbia 12:233,234;25:242 Euphorbia acaulis 9:265,267,288 Euphorbia brachypoda 28:400 Euphorbia caudicifolia 9:265 Euphorbiafidjiana 9:265-292;15:385 Euphorbiafisheriana 22:520 Euphorbia genera 27:830 Euphorbia helioscopia 9:265;23:406 Euphorbia hirta L. 22:520;23:405 for convulsions 22:520 Euphorbiajolkinii 9:265 Euphorbia lagascae 9:391 Euphorbia laterifolia 2:262 Euphorbia lathyris 24:273 Euphorbia maculata 23:406 Euphorbia maddeni 25:594 Euphorbia milii 5:678 Euphorbia myikae 22:520 Euphorbia nerifolia 7:152-15.4 Euphorbia nyikae Pax. 22:520 for epilepsy 22:520 Euphorbia obovalifolia"s latex 28:400 acaricidal properties of 28:400 Euphorbia pallasii 9:265,288 Euphorbia pekinensis 29:579 Euphorbia poisonii 2:261 Euphorbia prostrata 23:406
Euphorbia quiquecostata 29:103 Euphorbia resinifera 30:193 resiniferatoxin from 30:193
Euphorbia sp. 9:265,267,20:19 Euphorbia tirucalli L. 22:520;23:406 Euphorbia triaculeata 9:265 Euphorbia watanabei 23:406 Euphorbiaceae 23:405;25:242,243,245 Euphorbin A 23:405,413 Euphorbin C 23:405 Euphorblaceaephyllantus 22:720 Euphoria 21:101 Euplaxaura erecta 14:315 Eupomatenoid-5 26:202 Eupomatenoid-6 26:232 Eupomatia laurina 24:790 Euponera sp. 5:224 Euretaster insignis "/:304,94,45 Eurobustin A 23:405 Eurobustin B 23:405 Euroglyphus maynei 28:417 Europhthalma 6:422-434 Europine 26:874 Europine N-oxide 1:275 Europium sp. 5:325 Eurotium chevalieri 26:1091,1093, 1094,1097-1099 Eurycoma longifolia 7:393;23:300; 24:282 Eurycomalactone 7:393;11:71 Eurycomanol 7:393 Eurycomanone 7:393 (-)-Euryfuran 4:404 from Hysselodoris califomiensis 4:404 from Hysselodorisporterea 4:404 (+)-Euryfuran 6:28 from (+)-confertifoline 6:28 from (+)-manool 6:28 from Dysidia herbacea 4:404 from Euryspongia species 4:404; 6:20 from Hypselodoris califorensis 6:20 from Hypselodorisporterae 6:20 from manool 4:422-424 from trimethyl decalone 6:20
317 synthesis of 6:20,28,116,403, 422-424 Euryspongia 28:667 15-acetylthioxyfurodysin from 28:667 Euryspongia arenaria 25:703 Euryspongia deliculata 25:694 Euryspongia sp. 4:404 Euscaphic acid 29:575 effects on HIV- 1 protease 29:575 Eustigmatophyceae 6:134 Euterpe spp. 22:355 Euthyneura 21:3 Euthyroideones A-C 25:862,863 Euthyroideones 25:862 Euthyroides episcopalis 25:862;28:621 euthyroideones from 28:621 Eutreptiellanone 6:150,151,153 Eutypa lata 21:204 Euxanmodin A 20:277 Euxlophorine A 1:127 Evan's alkylation 19:62 Evan's reduction 18:253 Evans aldol methodology 16:483 Evans aldol-condensation reaction 30:13,33 Evans asymmetric alkylation 1:455,456, 469,604 Evans asymmetric induction procedure 14:534 Evan's asymmetric strategy 12:435,436 Evan's chiral auxiliaries 12:435-438 Evans chiral oxazolidine 26:1226 Evans oxazolidinone-mediated syn-aldol condensations 30:44 Evan's rearrangement 16:296 Evan's-Cope reaction 12:193 Evan's-Cope ring expansion 12:192 Evasoteria troschelii 25:813 Evening primrose oil 13:658,659 Evernia prunastri 5:310-312,322 L-Evernitrose 19:118 Evodia rutaecarpa 26:487 Evodiopanax innovans 29:573 Evolution 18:677-728 Evolutionary aspects 9:591-609 of vitamin B ~2biosynthesis 9:591-609
Evolutionary molecular modeling 21:3,5,104,107 of alkaloids 21:102 Evonine 23:678 Evoninic acid 23:674 Evoninol 18:747;23:674 Evuncifer ether 14:452,463 from Amitermes evuncifer 14:452,463 from Amitermes excellens 14:452 from Amitermes messinae 14:452 Exact vs. nominal mass 2:44 Exaltolide 19:118 Excelsin 7:398 Excisanin A 15:171;29:101 activity in EBV bioassay system 29:102 activity in NFkB bioassay system 29:101 activity in NO bioassay system 29:101 constiutents activity in skin-1 bioassay system 29:102 from Rabdosia excisa 15:171 from Rabdosia inflexa 15:172 from Rabdosia macrocalyx var. jiuhua 15:173 from Rabdosia serra 15:174 Excisanin B 15:171 from Rabdosia excisa 15:171 from Rabdosia macrocalyx var. jiuhua 15:173 Excisanin C 15:115,121,129,171 Exciton interaction 2:164 Exciton-chirality method 18:748 Excoecaria agallocha 7:176178,180,183,195 ;22:520;29:102 activity in EBV/skin-1 bioassay systems 29:102 (13R,14R)-ent-8a,13;14,15diepoxy- 13-epi-labdan-3p-ol from 29:102 ent- 13-epi-8,13-epoxy-2,3secolabd- 14-ene-2,3- dioic acid 3-methyl ester from 29:102 ent- 13-epi-8,13-epoxy-2-hydoxylabd- 1-en-3-one from 29:102
318
ent- 13-epi-8,13-epoxy-2-oxa-3oxolabd- 14-ene- 1R-carboxylic acid methyl from 29:102 excoecarin A from 29:102 excoecarin B from 29:102 excoecarin F dimethyl ester from 29:102 excoecarin H methyl ester from 29:102 excoecarin from 29:102 ent- 16-hydroxy-3-oxo- 13-epimanoyloxide from 29:102 11 [3-hydroxy-ribenone from 29:102 ent- 13-epi-manoyloxide from 29:102 for epilepsy 22:520 Excoecaria kawakamii 23:406 Excoecarianin A 23:406 Excoecarianin B 23:406 Excoecarin D 29:100 activity in EBV assay system 29:100 Excoecarin E 29:100 activity in EBV assay system 29:100 Excoecarin M dimethyl ester 29:101 activity in EBV bioassay system 29:101 Excoecarin-N-dimethyl ester 29:100 activity in EBV assay system 29:100 Exelsine 23:710 Exencephalic hamster fetuses 23:570 Exencephaly 7:20,21 Exidonin (rabdosin B) 15:143,152, 160,172,173 from Rabdosia henryi 15:172 from Rabdosiajaponica 15:172 from Rabdosia longituba 15:173 Exifone 25:349,350,351 2,3,4,3',4',5'-hexahydroxybenzophenone 25:349 Exiguaflavanone 26:801,803 Exo addition 8:160,161 Exo orientation 14:753 Exo-enamine system 30:443
(+)-C-2'-ara-Exo-enol tautomer 14:101 fluoroguanosine 10:609 antiviral activity of 10:609 Exoerythrocytic cycle 26:781 Exogenous compounds 22:4 Exogenous peptide signals 25:393 exo-glycal 30:458 conversion to labile epoxide 30:458 Exons 13:290 3'-Exonuclease 13:288,291 Exonucleases 13:290,291 Exophiala dermatitidis 28:476 Exophilin A 25:723 Exophiola pisciphila 25:723 f. sp. gladioli 25:307 f. sp. melonis 25:307,411 f. sp. niveum 25:307 f. sp. tuberosi 25:307 sp. lycopersici 25:295,299,307, 312-314,316,318 Exopolyphosphatase 25:718 Exoproteases 25:331 5-exo-Trig aryl radical-alkene cyclization 3:327,328 Exo-a-galactosidase 25:438 Exo- a-mannosidase 25:436 Exo-fl-l,3-glucanase 10:526 Exo-fl-galactosidase 25:438 Expectorant 17:451 Expectorant activity 21:633;28:200 of genus Morus 28:200 Extracellular LRR domains 25:401 Extracellular polysaccharides 30:421 Extracellular promastigote 26:790 toxicity assays for 26:790 Extracellular signal regulated kinases 25:526 Extrachromosomal HBV DNA 20:541,544 Extraction 9:449,450;21:502-505 of essential oil 21:573-577 Extracts of Geranii 27:414 effects on serum total cholesterol 27:414 Eye fatigue 30:64 use of carp in 30:64 Ezoalantonin 7:233
319 Ezomontanin 7:235 Ezomycin A-1 4:246,247 Ezomycin A-2 4:245,247 Ezomycins 1:422,431 synthesis of 1:422,431 for preparation of phytotherapeutic drugs 30:750 z-Facial selection 12:419-422 in methoxybromination 12:419-422 in methoxyselenylation 12:421, 422 reversed 12:419-422 Facial selectivity 10:36 F-Actin 22:33 Factor-a-dependent inflammatory liver injury 25:459 Fagaceae 23:403 Fagara macrophylla 7:427;27:168 Fagara sp. 27:164 Fagara xanthoxyloides Lam. 27:159 Fagaridine 14:783 ),-Fagarine 20:539,540 a-Fagarine 25:539 Fagarine I 21:68 Fagaronine 3:430;14:769,776,777; 13:656,769,770,775-777;22:27 Fagaropsis angolensis 27:164 Faglis sylvatica 25:662 Fagomine 7:15,10:543,544;22:184 Fagopyrum esculentum 21:527;29:608 Fagraea racemosa 26:268 (+)-epiresinol from 26:268 (+)-isolariciresinol from 26:268 (+)-pinresinol from 26:268 Falcaria sp. 27:686 Falcaria vulgaris 27:422 Falcarindiol 7:415;25:471,476 Falcipain 25:331 inhibition of 25:331 Fallacinol 22:609,610 Fallopiajaponica 22:608 Fallopia sachalinenesis 22:608 Falvanones 23:742 Famciclovir 20:534 Fames spp. 24:172 a-Famesene 25:546
fl-Famesene 25:546 Famotidine 25:612 FAMSO 6:311-313 aldehyde synthesis by 6:311-313 alkylation of 6:313,315,316 dianion of 6:323-325 methyl methylthiomethyl sulfoxide in 6:309-325 organic synthesis by 6:311-323 oxidation of 6:311 preparation of 6:309-311 Fana zava 23:659 Fangchinoline (bisbenzylisoquinoline) 29:578 effects on ACE 29:578 Faradiol (taraxast-20-ene-3 p, 16[~-diol) 25:57,58,62,63 ;29:586 effects on CHY 29:586 Faradiol 3-O-myristate (taraxast-20-ene313,16f3-diol 3-O-myristate) 25:58; 29:586 effects on CHY 29:586 Farensyl pyrophosphate 25:237 (+)-Fargesin 26:201,267 Fargesin 26:241 as PAF-induced inhibitor 26:241 Fargesone A-C 26:233 Farmosan gorgonian 25:690 Farnesal 8:19;22:379 E isomer 8:19 oxidation with SeO4/t-BuOOH 8:19 oxidation with BaMnO4 8:19 reaction with ethyl 1-diethylphosphono-2-methylbutanoate 8:18,19 reduction with LiA1H4 8:19 Z isomer 8:19 Farnesane 23:546 Farnesane sesquiterpenes 17:155 [3-Farnesene 7:100,101,103,121123;27:586 Farnesoic acid 22:379 E,E-Farnesol 1:656 Farnesol 7:108,125,8:222,20:88; 21:589,595;22:401 ;25:125,162,165168;26:331,332;27:586 trans-trans-Farnesol 23:802
320
(E,E)-Famesol derivatives 1:657 cis, trans-Famesol pyrophospate 5:730,731 (Z,E)-Famesols 8:75 (E,E)-Famesols 8:75,77 (E,E)-Famesyl acetate 1:663 Famesyl acetate 8:197,198 cis-Famesyl diphosphate 21:230 Famesyl diphosphate 7:324;22:253 Famesyl isothicyanate 21:346;25:854 Famesyl pyrophosphate 6:247,248; 22:253,635,636,637 Famesylation 24:409-410 of protein 24:409-410 Famesyl-protein transferase 24:403-464 as natural product inhibitor 24:403-464 for cancer chemotherapy 24:403-464 (E,E)-Famesylsulfone 1:657 Famesyltransferase 22:257 Famochrol 7:224 Fascaplysin 5:411,412 Fascaplysinopsis sp. 5:411 Fasciospongia cavernosa 25:688, 697,703 Fasciospongia rimosa 19:568;25:874 Fasicularin 25:860 Fast Atom Bombardment (FAB) 24:138 of saponins 24:138 Fast oligonucleotide deprotection (FOD) 13:266 Fat 27:402 hydrolysis of 27:402 Fat cell 27:393 biological activity of 27:393 Fatty acid 11:191;21:187,196 antileukemic activity of 7:24 biosynthesis of 11:191 by condensation of malonyl unit 11:191 metabolites derived from 21:187,196 oxidative degradation of 13:303306 stereochemical course of 11:191 Fatty acid components 28:565 of carp oil 28:565 of tuna oil 28:565
Fatty acid synthase type-I 25:500,501 Favorskii reaction 6:335 Favorskii rearrangement 8:225 ;10:410; 16:242;20:69,70 (+)-Faxiresinol- 1-[3-D-glucoside 5:524, 538,542,543 FDP aldolase 14:176 Fe(IlI) protoporphyrin 25:332 FeCla-induced epilepsy 22:509 Feist's acid 10:618 Felbamate 22:508 Felidae 7:7 Felikiol 5:736 Feline leukemia virus (FeLV) 21:646 anti-Felkin product 30:17 Felkin-AHN model 11:234,440,474, 643 ;12:21 ;19:474 Felkin-ANH conformation 3:255,134 Felkin-ANH transition state 1:402,406, 423 Felkin-Nguyen (Anh) 8:213 a-Fenchol 25:154 (+)-Fenchone 16:268 from Eremophila caerulea 15:227 Fenchone 4:649;20:16;21:599 Fenestrene (lauren-l-ene) 3:117-124 synthesis of 3:117-124 Fenfangjine A (bisbenzylisoquinoline) 29:578 effects on ACE 29:578 Fenoprofen 6:323 Fentanyl 30:198 Fenton process 25:931 Fenton reaction 22:316,327;25:330,634, 644;26:975,995 Fercolide 5:723,724 Fercomin 5:723,724,728 Fernenol 7:218 fromArtemisia vulgaris 7:218 Feronia elephatum 21:600 Ferredoxin-NAD oxidoreductase 20:835 Ferrichrome 9:551,555 Ferrier reaction 10:347,419,433-437, 510 Ferrier rearrangement 13:191,200,201, 203,210
321
Ferrier-type reactions 3:212,213 elimination-addition by 3:212, 213 filifolone by 3:40 synthesis of 3:40 Ferrihemoglobin 26:985,986,991 -mediated oxidation 26:991 Ferri-pyoverdins 9:553 Ferritin 22:327 Ferroprotoporphyrin IX 20:518 Ferrous sulphate reduction 4:422,432 Ferruginol 2:402,403;14:668,670, 674,689,690 from Salvia candidissima 20:660 from Salvia limbata 20:673 from Salvia montbretii 20:666 from Salvia napifolia 20:670 Ferruginyl 12-methyl ether 20:665,666 from Salvia pomifera 20:665,666 Ferry linyoglobin 25:934 Fertility regulation 13:658 Fertility-regulating agent 13:658 Ferugin 5:725,726 Ferula akitschkensis 5:723 Ferula alliacea 22:521 for epilepsy,hysteria and infantile convulsions 22:521 Ferula arrigonii 24:81 Ferula communis subsp, communis 5:723; 8:57 Ferula elaeochytris 5:723 Ferula foetida 22:521 for convulsions 22:521 Ferula galbaniflua 19:157-158;22:521 for epilepsy 22:521 Ferulajaeschkeana 5:725 Ferulakaratavika 1:660 Ferula lancerottensis 5:725,727 Ferula lapidosa 5:723 Ferula linkii 5:725,734;29:91 Ferula pallida 5:723 Ferula rubicaulis 19:158 Ferula sp. 5:721,732 Ferula tenuisecta 5:723 Ferula tingitana 5:723 Ferulamide derivative 22:490 Ferulate 5-hydroxylase 5:468,469 ferulic (3-methoxy-4-hydroxy) as 28:261
p-coumaric (4-hydroxy) acid as 28:261 sinapic (3,5-dimethoxy-4hydroxy) as 28:261 Ferulic acid 5:469,470,474,475,479, 495 ;21:618 ;23:537,551,744,745; 25:56,57,653,662,665,671,920; 27:746;28:262 in citrus juices 28:262 in cereal brans 28:262 in coffee 28:262 in sugar beet fibre 28:262 E-Ferulic acid 5:472 Z-Ferulic acid 5:472 Ferulic acid dimers 27:757 structure of 27:757 Ferulic acid ester 25:655,665 Ferulic and p-coumaric acid 25:920 Ferulidin acetate 7:236 Feruloyl CoA 25:653 Feruloyl malate 23:761 Feruloyl quinic acid 23:745 3-O-Femloyl-4-O-caffeoylquinic acid 25:920 Feruloylglycine 25:923 3-O-Feruloylquinic acid 25:920 Feruone 5:724,725 Ferutidin 5:622,623 Ferutinin 5:722,723,731,732 Festigiolide 5:728 (+)-Festuclavine 18:386 Fetizon oxidation 4:340,343,370 Fetizon's intermediate 12:196,198 Fetizon's photochemical route 12:195 Fetizon's reagent 1:349,366,508,570; 18:28 Fever 22:532 Sida cordifolia L. for 22:532 Feverfew 13:660 F-gitonin 25:308 F-I 30:826 as isozyme 30:826 F-I-0 30:826 as isozyme 30:826 F-I-2 30:826 as isozyme 30:826 FIavonol glycoside 22:644
322
Fibrinogen 30:834,838 conversion of 30:834 fibrin from 30:834 Fibrinolysis rate 30:841 effect of G-90 30:841 Fibrinolytic activity 21:670;30:826,827 from earthworm Eisenia fetida 30:826 Fibrinolytic agent 30:839 in disease prevention 30:839 in treatment of clotting disease 30:839 in acute myocardial infarction 30:839 in cerebral thrombus 30:839 Fibrinolytic effect 30:840 of lyophilized powder 30:840 Fibrinolytic efficacy 30:839 in vitro 30:839 Fibrinolytic enzyme 30:825,827,839 from Lumbricus rubellus 30.'825 from Lumbricus bimastus 30:827 in thrombosis treatment 30:839 recombinant prourokinase (proUK) as 30:839 recombinant tissue-type plasminogen activator as 30:839 staphylokinase as 30:839 streptokinase (SK) as 30:839 urokinase (UK) 30:839 Fibrinolytic mechanism 30:837 Fibrinolytic medicine 30:842 activity of 30:842 half life of 30:842 immunogencitity of 30:842 properties of 30:842 re-occlusion rate of 30:842 Fibroblast growth factor 30:56 angiogenesis by 30:56 Ficin flavonoids 26:744 Ficisterol 9:40 biosynthesis of 9:40 Ficus brachypoda's latex 28:400 acaricidal properties of 28:400 Ficus capensis 22:521 for convulsions 22:521 Ficus costata 2:231 Ficus diversiformis 2:231
Ficus elastica 8:66 Ficus fergusoni 2:231 Ficus microcarpa 29:788 Ficus pyrifolia 20:522 Field desorption (FD) 2:46-48,632,645, 467,487;24:138 of saponins 24:138 Field-collected samples 29:254 cytotoxic activity of 29:256 Fieser's solution 19:653 Figepitope 25:394,395 F-I-I 30:826 as isozyme 30:826 F-II 30:830,836,838 C-terminal region of 30:838 inhibition of 30:836 N-terminal region of 30:838 secondary structure of 30:830 F-II cleavage 30:838 of human plasminogen 30:838 F-Ill 30:826 as isozyme 30:826 F-III- 1 30:826,828,830,833,836 as isozyme 30:826 caseinolytic activity of 30:833 inhibition by Soybean trypsin inhibitors (SBTI) 30:836 inhibition of 30:836 N-terminal sequences of 30:828 secondary structures of 30:830 F-III-l(2) 30:831 homologous sequences of 30:831 F-III-2 30:826,828,830,833 as isozymes 30:826 fibrinolytic activity of 30:833 N-terminal sequences of 30:828 secondary structures of 30:830 Fijian sample 28:337 varacin from 28:637 Filamentous fungi 9:203 Filifolide A 7:208 from Artemisiafilifolia 7:208 Filifolone 7:208 fromArtemisia filifolia 7:208 Filipendula ulmaria 23:397 Filipin 24:548 antiviral microbial-derived compound 24:548
323
Filospadin flavonoids 26:744 Filter-sterilized pectinase 25:485 Finavarrene 21:305 Finitin 7:212,232 Finkelstein substitution 6:310 Fire ant 1:682;6:422 First-order kinetics 30:786 Fischer carbene complexes 1:505,506 Fischer indole reaction 14:845 Fischer indole synthesis 1:79,144,152, 284;11:285,492 Fischer indolization 1:15,51,60 Fischer projection 11:422,423 Fischerella 26:366 Fischerella ambigua 23:342; 25:792;26:364 Fischerella major 25:802 Fischerella muscicola 25:802; 26:364,366 Fischerellin 26:370,374 Fischerellin A 26:364,368 Fischer-Helferich procedure 4:222 Fischer-Kiliani synthesis 4:157-159, 175,179 Fisetin (3,7,3',4'-tetrahydroxyflavone) 22:322,326;25:541,543,544;26:757, 758;29:579 effects on ACE 29:579 Fisetin 29:572,581,582,585 effects on HIV- 1 protease 29:572 effects on LELA 29:585 effects on MMP 29:582 effects on NEP 29:581 Fish oils 28:566 anti-tumor activity of 28:566 Fisher-Irwin test 9:386 Fits 22:518,524 Cuscuta europea L. for 22:518 Jatropha curcas L. for 22:524 Fits in children 22:531 Ruta graveolens L. for 22:531 Fitzsimmon cycloaddition 11:447 FK 22:257,258,506 FK 508 25:464 as immunosuppressive drug 25:464 FK-506 8:273 FKBP12 22:258
FL3-27 gene proprotein 29:592 effects on cysteine protease 29:592 Flabellin 25:394;27:578 Flagellin protein 25:394 Flagpole type interaction 14:736 Flammulina velutipes 5:289 Flash pyrolysis 1:250 Flash vacuum pyrolysis 3:27,588 Flash vacuum thermolysis 1:337 Flatulence 5:754 Flavan-3-diols (leucocyanidins) 22:420 Flavan-3-ols 22:420;23:742,749, 772;28:273 (+)-catechin 28:273 epicatechin 28:273 Flavanolols (dihydroflavonols) 22:421 Flavanols 22:420,421 ;28:272 structure of 28:272 Flavanones 17:143-144,580;22:312, 420,432;28:270 eriodictyol 28:270 hesperetin 28:270 hesperidin 28:270 in chick peas 28:271 m citrus fruits 28:271 m cumin 28:271 in hawthorn berry 28:271 in licorice 28:271 in peppermint 28:271 in rowanberry 28:271 isosalipurpurin (chalcone) as 28:271 phloretin (dihydrochalcone) as 28:271 Flavans 7:192;22:420, Flavin adenine dinucleotide 26:917,918, 951 Flavin mononucleotide 26:917,918,951 Flavobacter dehydrogenans 9:417,418 Flavobacterium 4:432 Flavobacterium sp. 7:330,336,341345,347-351,358,360,363 ;25:868 Flavocarpine 1:124,135,153,156 Flavocristamides A and B 25:868,869, 903 Flavoglaucin 9:313 Flavokawin B 23:808 Flavologlycan polymer 7:193
324
3,5,7,4'-Flavone 27:844 Flavone 4:377,12,13,622,624,634,737639,643,651,653,252 Flavone glycosides 30:235 acidic hydrolysis of 30:235 sugar moieties of 30:235 Flavones 23:742,772;28:266,267, 285;30:236,285 absorption of 28:285 apigenin 28:267 as plant tissue color 28:267 chrysin 28:267 diosmetin 28:267 isoorientin 28:267 isovitexin 28:267 lutcolin 28:267 orientin 28:267 pinocembrin 28:267 ~3C-NMR spectral data of 30:285 UV spectra of 30:236 vitexin 28:267 Flavonoid aglycones 21:552 Flavonoid C-glycosides 5:643;10:362 Flavonoid disulphates 5:655 Flavonoid glucuronide 5:643 Flavonoid glycosides 5:632,633, 641,645,649,656,658,664,665; 23:487,521 Flavonoid p-coumaroyl glycosides 30:274 genkwanin from 30:274 Flavonoid sulphate 5:655,663,664 Flavonoid-6,7-disulphate 5:648 Flavonoidal alkaloids 21:130 synthesis of 21:130 Flavonoids 4:367,5:3,12,467,510,511, 621-624,627,630,632,637,641,642, 645,649-652,659-662,666,757,756; 7:202,206,208,220,226-228,411-413, 427;9:390,15:30;17:341 ;20:283,709; 21:457,459;22:419,307,311,344;23:3 42,536,553,638,747,802;24:215,218228,799;25:607 ;27:425,504 ;30:56, 70,233,234,238,241,272-277,284285,619,628,629,724,725,562 activity of 27:504 against Staphyllococcus aureus 30:629 anti-thrombic actions of 30:70
as glycosides 30:724 biogenetically formation of 30:233 biological activity of 27:425 effect on prostaglandin E2dependent cytoprotection 25:607 from luteolin 30:619 from miscellaneous genera 30:272-277 1H-NMR spectra of 30:238,284 identification of 30:234,235 inhibitory activity of 30:629 isolation of 30:233-236,619 methoxyl protons of 30:241 purification of 30:233,234 of citrus fruits 23:747 wound-healing effect of 30:628 Flavonols 5:192,622,624,626,628,634, 637;17:117,139-141;22:312;23:553, 742,772;26:744 ;28:264,265,284; 30:616 amentoflavone 30:616 as sulfated glycolipid 28:718 biflavones 13-biapigenin 30:616 eicosane- 1,16-disulfate from 28:718 Forbesin 28:718 from onions 28:284 glycoside derivatives 30:616 glycosides of 28:284 hyperoside 30:616 in kaempferol 28:265 in plant foods 28:265 in quercetin 28:265 isoquercitin 30:616 quercitin 30:616 rutin 30:616 structure of 28:264 Flavonol 3-methyl ethers 7:411,412 Flavonol glycosides 23:758 Flavonol methyl ethers 7:411,412 Flavonol myricetin 770 Flavonol quercetin 26:753 Flavonone 5:643;26:743,744;27:893 Flavopereirine 1:124,129-136,141143,145,147,149,153,155,156
325
Flavopiridol 21:153 anticancer activity of 21:135,136 clinical usage of 21:138 Flavopiridol-induced cytotoxicity 21:136 Flavoprotein 22:12 Flavoprotein oxidase 22:5 Flavors 13:322-345 analysis of 13:322-345 biogeneration of 13:295-345 legislation of 13:337-340 Flavour materials 27:374 from Labiatae 27:374 Flavoxanthin 20:727 Flavylium salts 22:420 Flemingia congesta 29:775 Flemingia rhodocarpa 29:775 Flemingia strobilifera 22:521 for epilepsy, hysteria and nocturnal epilepsy 22:521 Flemingia wallichi 29:775 Flexibacter elegans 9:323 Flexibilene 8:16,17 synthesis of 8:16,17 Flexicaulin A 15:117,124,131,171 Flexirubin 9:314,323,328,329,368 Flexuosol A 26:569 Florisil column chromatography 14:661 Flourinated erythromycin 25:780 5-Flourouracil (5FU)-induced lethality 25:447,448 protective effect 25:447,448 Flouro-[3-1actone 16:727-744 Flow cytometry analysis 24:220-239 Flu 30:691 Maytenus amazonica for 30:691 Fluconazole 22:60,248 Flucytosine Flueggea virosa 22:521 for epilepsy 22:521 Fluometuron 25:669 Fluorene 6:173 Fluorenone 6:176-181;26:655 N(2-Fluorenyl) guanidine 8:382,383 Fluorenylguanidine 8:382 N-9-Fluorenylmethyloxycarbonyl (fmoc) 4:289 Fluorescence indicator fura-2 18:856 Fluorescence inducing reagents 9:453
Fluorescence spectrometry 26:378 Fluorescent antibodies 30:841 Fluoresein 5'-isothiocynate (FITC) 25:446 4-Fluorestradiol 5:447,448,451-454 8'-Fluorinated abscisic acid analogs 27:346 Fluorinated analogues 9:517,518 Fluorinated compounds 29:343 4-fluorothreonine as 29:343 fluoroacetate as 29:343 Fluorinated probes 27:333 activity of 27:333 Fluorination 13:81-83 of alkylmalonate 13:83 of chiral half-esters 13:81 of monalkyl malonic acid 13:81 with 1-fluoro-2,4,6-trimethylp yridinum- trifluoro me thane sulfonate 13:82 4-Fluoro-2-hydroxyestradiol 5:454 4-Fluoro-2-methoxyestradiol-3-methyl ether 5:453 5-Fluoro-6-fluoro-substituted alkaloids 29:344 as synthetic fluorinated compounds 29:344 8'-Fluoro-abscisic acid 27:335 3'-Fluoro-abscisic acid 27:349 16-Fluoroaphidicolin 22:235 Fluorocarbon extraction 21:577 C-Fluorocurarine 1:36 Fluorocurarine 1:41,46-48 synthesis of 1:41,46-48 5-Fluorocytosine 22:60 8-Fluoroerythromycin A (flurithromycin) 13:166 synthesis of 13:166 3-Fluoroestr- 1,3,5 (10)-trien- 17~-ol 5:449 2-Fluoroestradiol 5:447-456 Fluoroestrogen 5:451,453,454 Fluoroglycosides 10:368-370 6-Fluoroheptulosonic analogues 30:473 ct-Fluoroketone 5:449 13-Fluoroketone 5:4502 ct-Fluoromethylamino acids 10:147,148
326 5-Fluoro-Nb-acetyltryptamine 29:344 as synthetic fluorinated compounds 29:344 25-Fluoroponasterone A 29:19 as synthetic ecdysteroid analogues 29:19 Fluoropyrimidines 22:58,63 Fluorosampangine 23:64Fluorosugars 10:368-370 Fluorosulfonic acid 30:215 1-Fluorotetrahydrocannabinol 30:196 Fluorotryptamines 29:344 as synthetic fluorinated compounds 29:344 5-Fluorouracil (5-FU) 21:136;22:60; 23:306;25:447,448;27:436;795; 28:562,559 as cancer drug 28:559 gastrointestinal toxicity by 28:562 immunotoxicity by 28:562 levels in mice plasma 28:567 myelotoxicity by 28:562 prophylactic effect against mylosuppression 25:447,448 5-Fluorouracil-induced myelosuppression 25:429 6-Fluoro-13-hydroxy-Nb-acetyltryptamine 29:344 synthetic fluorinated compounds 29:344 5-Fluoro-13-hydroxy-Nb-acetyltryptamine 29:344 as synthetic fluorinated compounds 29:344 Fluoxetine 22:672 Flurithromycin (8-fluroroerythromycin A) 13:166 synthesis of 13:166 Fluromalonate 13:82 Flustra foliacea 17:80,85,87,102,103; 18:689,692,693,708,725 Flustra papyracea 17:86 Flustrabromine 18:691 Flustramide A 18:691 Flustramide B 18:691 Flustramines 17:87 Flustramine A 18:690,691 Flustramine B 18:690,691
Flustramlne C 18:690,691 Flustramlne D 18:690,691 Flustramlne E 18:690,691 Flustramlne D-N-oxide 18:691 Flustraminol A 18:691 Flustraminol B 18:691 Flustrarine B 18:690 Flustriidae 18:690-693 Flutropium 22:738 FMBoA 27:211 FMDV 24:524 activity of actinoplanic acids against 24:524 FMN-binding domain 26:920 FNE 8:396 FOD (fast oligonucleotide deprotection) 13:361,267,268 Foenicuioside 1-IV 26:556,560 Foeniculum 21:619 oil of 21:619 Foeniculum vulgare Mill 5:473;21:599; 27:16;28:408 Foens-forming units (FFU) 24:483 Fogomine 10:567 Fogs grandifolia 5:472 Foliacraline 13:394 Folin-Ciocalteu method 21:508 Foliol 29:100 activity in NFkB bioassay system 29:100 Folk medicine 28:202;30:203,603 from genus Hypericum 30:603 use of Artocarpus venenosa in 28:202 use of ginseng root in 30:203 Follicle-stimulating hormone 27:796 Fomes annosus 21:212,232 Fommanosin 13:6 Food mutagens 8:378,388,389 Food preservation 21:617 Footprinting 5:580 Forbeside A (versicoside A) 7:288,293 Forbeside B (glycoside B2) 7:288,293 Forbeside C (asterosaponin 1) 7:288, 293 Forbesides A-C 7:292 Force field method 9:281 Forest tent caterpillar 24:865 bioassay of 24:865
327 Formaldehyde dimethyl dithioacetal 6:311 (S)-Formaldehyde di-p-tolyl dithoacetal S-oxide 6:346,437 in (S)-propranolol synthesis 6:346,437 synthesis of 6:343,344 Formaldehyde induced arthritis 25:46 Formalin 30:205 inflammatory pain induction by 30:205 neurogenic pain induction by 30:205 Formalin test 30:207 activity of 13-narin-II8-4'-OMeeridictoyol in 30:207 role ofbiflavonoid 30:207 Formamidokalihinols 21:366 Formaononetin 28:228 biological activity of 28:228 Formation 27:346,877 of(+)-abscisic acid 27:346 of(-)-abscisic acid 27:346 of (HOABA) 27:346 ofphaseic acid 27:346 Formic acid 28:384 as miticide 28:384 Formica 6:454 Formicids 6:421 (+)-N-Formylcyclomicrobuxeine 2:196,197 Formononetin 26:745;28:224,241 anti-microbial activity of 28:224 anti-Helicobacter pylori activity of 28:241 Formosanin C 21:651 Formosanine 25:25,26 Formycins A 10:356 Formycins B 10:356,357 Formylation 6:74 N-Formyl lactam 12:390,392 Formyl methionyl-leucyl phenylalanine (fMLP) 25:275 Formyl piperzinedione 12:66 3-Formyl rifamycin SV 21:421 1-Formyl- 1,4a-trans-isoquinolines 12:469 Na-Formyl- 12-methoxyechitamidine 1:36
3-Formyl-34a-trans-isoquinolines 12:469 2-Formyl-4,5-diphenyloxazole 14:598 1-O-Formyl-4'-Demethoxy-3',4'-methylenedioxymethylrocaglate 26:203 6-Formyl-5-isopropyl-3,7-dimethyl- 1Hinden- 1-one 14:328 4-Formyl- 8-hydroxyquinoline 2:232, 233;5:752,753 Formylation-diazotrans fer procedure 10:594,595 Formylchromane 4:495 7-Formyldehydrohernangerine 30:563, 589 activity in human cancer cell lines 30:589 cytotoxic effect of 30:589 from genus Hernandia 30:563 from Hernandia nymphaeiJolia 30.563 (+)-N-Formyldehydroovigerine 30:563, 589 activity in human cancer cell lines 30:589 activity in murine cancer cell lines 30:589 cytotoxic effect of 30:589 7-Formyldehydroovigerine 30:581 activity in human cancer cell lines 30:589 activity in murine cancer cell lines 30:589 cytotoxic effect of 30:589 ~H-NMR spectrum of 30:581 HREIMS of 30:581 hydrogen-bonding of 30:581 IR spectrum of 30:581 isolation of 30:581 molecular formula of 30:581 UV absorptions of 30:581 Na-Formylechitamidine 1:36 3-Formylguaiazulene 14:315 (+)-N-Formylharappamine 2:177,178 N'-Formyl-kynurenine 26:966,998 N-Formylnornantenine 30:563 from genus Hernandia 30:563 from Hernandia sonora 30:563 (+)-N-Formylnornantenine 30:563,589 activity in human cancer cell
328
lines 30:589 activity in murine cancer cell lines 30:589 cytotoxic effect of 30:589 8-Formyloct-5-enoate 26:86 wittig reaction of 26:65,66,70, 72,73,75,81,83-91 (+)-N-Formylovigerine 30:563,582,589 activity in human cancer cell lines 30:589 activity in murine cancer cell lines 30:589 cytotoxic effect of 30:589 Formyloxy compound 11:298,299
trans-7-Formyloxy-8amethylindolizidine 12:288,289 (+)-Formylpapilicine 2:182,183,204 3-Formylrifamycin SV 12:37 N-Formylvinamidine 2:398 ct-Formyl-tx-phenyl acetic acid 10:408 Forosamine 5:614 Foroxymithine 15:449 Forscarnet 24:486,487 as anti-viral agent 24:486,487 Forskalinone 20:672 from Salviaforskahlei 20:672 from Salvia hierosolymitana 20:672 Forskolin 10:183;13:659;23:488; 25:256,261,262,264,265,268,270272,275,276,489,490,496,539; 29:102 activity in APO bioassay system 29:102 Forsythia 26:327 Forsythia intermedia 5:489-491,492, 494;26:156,174,177,223 (-)-arctigenin from 26:223 Forsythia koreana 26:237 Forsythia mandshurica Rupr. var. japonica Maxim 5:505,514516,520,523-525,531 Forsythia spp. 5:511-513,521;26:156, 157,235 pinoresinol monoglucoside from 26:235 Forsythia suspensa 5:489,506,522, 592,616;21:595;24:855;26:156,237,2 41
inhibition of cyclic adenosine monophosphate (c-AMP) phosphodiesterase 24:855 Forsythia suspensa var. fortunei 5:475 Forsythia viridissima Lindley 5:505, 506,514,522;26:237 Forsythiaside 5:506,509,512-514;25:543 Forsythosides A 16:628 Fortimicin 4:118 Fortunellin (5-hydroxy-7-glucosylrhamnosyl-4'-methoxyflavone) 29:572 effects on HIV- 1 protease 29:572 Forward mutation test 27:303 Forysthide aglycone dimethyl ester 16:294-295 synthesis 16:294-295 Fosarium oxysporum 25:314 Fosfonomycin 6:352 Fostreus 27:883 as phosphatase inhibitor 27:883 Four component condensation 12:11, 115,117 Four-carbon polar annulation 6:17,21, 29,30 Fourier transform methods 5:3 FPP 7:110,122 FPP mimetics 24:414,415 structures of 24:414,415 FPTase inhibition 24:403-464 by andrastins 24:452,453 by arteminolide 24:457 by desmethoxy streptonigrin 24:454 by gliotoxin 24:452 by lupane triterpenoides 24:457 by monoterpenes 24:461 by patulin 24:458 by rhombenone 24:456 by saquayamycnis 24:480 by SCH 24:58,207,278,450,451 by solandelactones 24:455 by valinuoctins 24:459 FPTase inhibitor 24:439 cembranolide as 24:439 structures of 24:444 Fractional distillation 21:578 Fragaria spp. 29:571,579,582
329
Fragmentation 25:255 ofmanoyl oxide 25:245, 248-250,253-255 Fragmentation-recombination 10:412 of e~,[3-unsaturated methoxymethyl ester 10:412 to c~-hydroxymethyl unsaturated ester 10:412 Fragranol 7:208 from Artemisiafragrans 7:208 Fragrant odor 2:278 of liverworts 2:278 Framework molecular models 17:490 Framoside 26:327,334,343 Frangufoline 22:8 Frangula-emodin 22:646 FRAP 22:258 Fraser-Reid synthesis 12:13,14 Fraxetin 5:497,515-519;23:356;26:314, 315,318,331-334,336-340,342 Fraxetin dimethyl ether 5:516 Fraxidin 5:516,225;26:315 Fraxin 5:515,516,520,521;26:314,317, 318,331-334,336,338-340,342 Fraxin methyl ether 5:516 Fraxinol 5:516,517,519;26:315 Fraxinol methyl ether 5:516 Fraxinus 26:327,333,343 Fraxinus bungeana 26:317 Fraxinus chinensis 26:317 Fraxinus formosana 26:327 Fraxinus insularis 26:321 insularoside from 26:321 Fraxinusjaponica Blume 5:505,514, 515,520,521,523-525,531 Fraxinus ornus 26:313-319,327,328, 330,332,334-340,341,343-345 antimicrobial activity of 26:334 Fraxinus rhyncehophyllus 13:660 Fraxinus spp. 26:315-318 Fraxinus stylosa 26:317 cichorin from 26:314 esculetin from 26:314 fraxetin from 26:314 hydroxycoumarin esculin from 26:314 quercetin from 26:314 quercetin-3,7-digalactoside from 26:314
quercetin-3-galactoside from 26:314 quercetin-3-glucoside from 26:314 rhamnetin from 26:314 rutin from 26:314 Fraxinus uhdei 26:321 uhoside from 26:321 ;28:598 from calcigeroside C! 28:598 from calcigeroside D~ 28:598 from cucumarioside G2 28:598 (+)-Fraxiresinol 5:524,535-538,542 (+)-6-epi-Fraxiresinol 5:542 (+)-Fraxiresinol dimethyl ether 5:542 Fredericamycin A 16:27 antitumor agent 16:27 antitumor antibiotic 16:27 synthesis of 16:27-74 Free bases 27:170 of QBA 27:170 preparation methods of 27:170 pseudobase of 27:171 Free fatty acid 27:404 biological activity of 27:404 Free radical condensation 10:355 Free radical cyclization 3:326 Free radical deoxygenation 6:21 Free radical scavenging activity 22:314 Free radicals 30:221,224 role in aging 30:224 role in atherosclerosis 30:224 role in cancer 30:224 role in cardiac diseases 30:224 role in diabetes 30:224 role in human diseases 30:224 role in inflammation 30:224 role in intestinal diseases 30:224 role in neurodegeneration 30:224 role in reperfusion injuries 30:224 role in respiratory disorders 30:224 Free sugars 10:389-394 Free-energy 27:340 of ABA 27:340 Freelingyne 10:167 synthesis of 10:167 from Eremophila freelingii
330 15:233 from E. rotundifolia 15:233 Fremy's salt 9:456,457,10:120,121; 14:780;19:653 French paradox effect 27:430 French research groups 29:498 homochiral (+)/(-)-calystegines B2 synthesis by 29:498 Frenolicin 4:591,592,594,609 synthesis of 4:591,592,594,609 5-O-Freuloylquinic acid 25:920 4-O-Freuloylquinic acid 25:920 Fridelane-type triterpene 30:697 Fridelin 27:590 4,9-Fridodriane 25:867 Frido-oleane 23:692 Friedal-Crafts acylation 8:16,13:448, 18:234 Friedal-Crafts reaction 1:499-501; 5:485;10:312,313;11:140,318,319; 14:7,670-676,681-684 ;19:306; 20:692 intramolecular 10:312,313, 11:140 Friedelane 25:54,59 Friedelan-3,21-dione 5:744,746 Friedelan-3fl-ol 7:167,168;22:536,542 Friedel-Crafts alkylation 6:61,62,74, 75;10:376;18:231 Friedel-Crafts annulation 18:70 Friedel-Crafts products 6:309 Friedelin 5:744,746;7:147,148,150, 161,162,189;18:770;21:690;23:702; 30:719 structure of 30:719 synthesis of 3:435 Friedelin derived triterpenes 7:145-153 epi-Friedelinol 27:590 Friedlander reaction 3:386 2 4 ,3 0-dino r-D: A-Friedoo l eanane 22:102 24-nor-D:A-Friedooleanane 22:102 Friedo-oleanenes 7:149,150 from Cassine balae 7:149,150 Fritsch-Buttenberg-Wiechell rearrangement 18:171 from anacardic acid 9:341 Fromia monilis 15:60 Frondogenin 7:277
Frondoside A 15:92 Frondoside B 15:94 Frondoside C 28:599 from sea cucumber 28:599 Frontal cortex 30:377 serotonin synthesis in 30:377 D-Fructofuranose 6:352,355,357,358 [~-D-Fructofuranosyl 1-thio-ct-Dglucopyranoside 8:322,325 a-D-Fructofuranosyl 1-thio-ct-Dglucopyranoside 8:323,326 synthesis of 8:323,326 D-Fructose 6:355 phosphorous analogues of 6:355 Fructose 7:181 Fructose content 27:311 Fructose-2,6-biphosphate 25:523 Fructose-6-phosphate-2-kinase 25:523 C-Fructosides 3:217 synthesis of 3:217 Fructus schisandraei 26:233 Fruit lactones 13:297 Fruit phenolics 23:745 in apples 745 in apricot 23:745 m cherry 23:746 m citrus 23:747 in grapefruit 23:747 in grapes 23:748 in lemon 23:747 in olive 23:749 in orange 23:747 in peach 23:749 in pear 23:750 m plums 23:750 in raspberry 23:750 in strawberry 23:752 Frullania dilatata 2:280,607 Frullania nisquallensis 2:280,471 Frullania tamarisci 2:278,280;9:254; 18:607,614,623 (-)-Frullanolide 18:607;20:471,472 Frullanolide 2:280,281 Frutescin 9:317 (+)-Fruticosonine 11:278,279,286 Frutinone A-C 7:415 5-FU (5-flourouracil) 25:450,453 5-FU derivatives 27:436
331 5-FU plus carp oil 28:566,568 effects on tumor growth 28:566 in sarcoma 180-bearing mice 28:566 5-FU plus tuna oil 28:566,568 effects on tumor growth 28:566 in sarcoma 180-bearing mice 28:566 5-FU treatment 25:449 Fuchs synthesis 18:892-895 Fuchsia 29:572 Fuchsiaefoline 5:128,387 Fucogalactomannans 5:289 Fucoidan 30:55-57,399,405 against human CMV 30:405 antitumor activity of 30:56 as antiviral agent 30:405 effect on angiogenesis 30:56 effect on body 30:56,57 effect on liver metastasis 30:55 effect on spleen or adipose tissue weight 30:56,57 effect on thymus 30:56,57 effect on tumor growth 30:55-57 from Fucus vesiculosus 30:399 from Laminariajaponica 30:56 9-(13-D-Fucopyranosyl) adenine 4:232 Fucosanthin 7:320,321 L-Fucose 23:163 et-L-Fucose 29:557 affinity chromatography of anti29:557 agar diffusion pattern of 29:558 as glycoconjugate 29:557 isoelectrofocusing of 29:559 Fucose 286-289,292-294,302 ~-L-Fucosidase 12:349 Fucosidases 7:41 Fucosterol 5:408,7:124 Fucosyltransferase 10:500,501 Fucoxanthin 6:133-137,139,141,142, 146;10:153 ;20:583,584;30:531 Fucoxanthin oxonium ion 30:518,519 structure of 30:519 Fucoxanthinol 6:135,136,142,143 Fucus garderi 26:1152 Fucus vesiculosus 25:717,725 Fuerstione 19:405
5-FU-induced adverse effect 25:449 5-FU-induced suppression of bone marrow hematopoiesis 25:454 Fukiic acid (phenolic acid) 29:582 effects on collagenase 29:582 synthesis from fukinolic acid 29:582 Fukinolic acid (phenylpropanoid ester) 29:582 effects on collagenase 29:582 (+)-Fukugetin (morelloflavone) 5:758 Fukumoto's approach 22:235 Fulica atra 5:837 Fuligo septica 21:413,29:236 fuligorubia A from 21:413 Fulvene 22:197,204,210,220 Fulvine 1:272,273 synthesis of 1:272,273 Fulvinic acid 1:263 synthesis of 1:263 Fulvoderivatives 7:459,460 Fulvoharpagide 7:459,460 Fulvoipolamiide 7:458,459 Fulvoiridoids 7:458 Fulvolamiol 7:459,460 Fulvoplumeirin 7:441,458,459,656 Fumagillin 22:261 ;26:458,459 Fumagillol 26:459 Fumarate dehydrogenase 26:800 Fumarates 8:142-144 Fumaric acid 7:180 Fumaricine 1:198,199,219 Fumaritridine 1:208,209 Fumaritrine 1:208,209,211,212 Fumarofine 1:207,209-211 Fumonisins 6:219,220,252;9:203, 204,214,215;13:530-533 Funco oreganus 5:836 Functional bioactivity 30:813 of [Tyr)Me)2-Phe] peptides 30:813 of Tyr(Me)2-Phe-NH2 30:813 of d-Tyr(Me)2-Phe-NH2 30:813 of Tyr(Me)z-d-Phe-NH2 30:813 of d-Tyr(Me)2-d-Phe-NH2 30:813 of Tyr(Me)2-Phe-G-V-V-NH2 30:813 of d-Tyr(Me)2-Phe-G-V-V-NH2
332
30:813 of Tyr(Me)2-d-Phe-G-V-V-NH2 30:813 of d-Tyr(Me)2-d-Phe-G-V-VNH2 30:813 Functional bioassay 30:809 activity of Tyr-Tic-NH2 in 30:809 activity of (Tic 2, LeuS)enkephalin in 30:809 activity of (Tic2)dermorphin in 30:809 activity of (tic2)DYN-A-(1-11)NH2 in 30:809 activity of (D-Ala,desGly2)DYN-A-(1-11)-NH2 in 30:809 activity of DYN-A-(1-11)-NH2 in 30:809 activity of (tic2)DYN-A-(1-13-)NH2 in 30:809 Functional group assays 21:508,511 Fungal [3-glucans 23:114,115 structure characteristic of 23:115 Fungal glycoprotein 25:396 Fungal polysaccharides 26:1124-1129 Fungal spore 9:219-248 Fungal tomatinase 25:316,321 Fungal toxin 1:289 synthesis of 1:289 Fungal-tomato pathogens 25:295,312 Fungi 2:341 Fungi and protozoa 18:785-814 Fungicidal activities 17:243;21:182, 192,266,275,276,277,285 ;28:146 of eliamid 28:146 Fungicidal isoflavans 27:498 Fungicidal properties 21:225 Fungicidal saponins 7:433 Fungicide thiazole 25:321 Fungicides 9:226;28:390 used of essential oil 28:415,390 Fungistatic activity 21:189,238 Fungitoxic compounds 22:73 Furan C-glycosides 10:349 Furan-based Diels-Alder approach 29:470 carbaaldopyranoses synthesis by 29:470
Furane 3:443 Furaneol 13:318,319 Furano flavonoids 26:744 1-Furano glycal derivative 30:455 conversion into 30:455 Furanoaphthoquinones 20:494 from Crescentia cujeta 20:494 Furanocoumarin 4:388,389,396,398; 7:433 ;9:402;18:978,979,985 ;20:497; 23:337,354 ;25:666 Furanodiene 29:88 activity in HPT assay system 29:88 activity in COX assay system 29:87 activity in iNOS assay system 29:87 activity in NFkB assay system 29:87 activity in NO assay system 29:87 activity in TPA bioassay system 29:103 Furano-guaian-4-ene 23:161 Furanoheliangolide sesquiterpenes 24:3,7,11-47 Furanoheliangolides 26:808 Furanoid 30:570 Furanoid C-glycosides 10:343,344 Furanoid compounds 3:55-58 synthesis of 3:55-58 Furanoid linalool oxide 25:141 cis and trans 25:143 Furanonaphthoquinones 5:16,17;30:314 13-Furanone 6:20 reaction wih 9-BBN 6:20 synthesis of 10:384 Furanosesquiterpenes 15:197,227-238; 23:202 Furanosyl C-glycosides 10:367 synthesis of 10:367 C~2-Furanoterpene furospongolide 25:697 Furanoterpene sulfates 25:688 Furanoterpenes 5:371,107;25:688 Furanoxides 30:530 Furans 17:324,585 Furanurono-6,1-1actone 14:180 Furanyl C-glycoside 10:391,392
333 Furfuryl (E)-2-(sulfonyl) acrylates 12:19 N-Furfuryl acryl amide cycloaddition 12:19 6-Furfurylaminopurine (kinetin) 7:90 Furfuryllithium 4:141,142 Furin 25:389 Furo [3,2-C]pyrid-4 (2H)-one 8:286 Furobenzazonine derivative 6:473,474 Furoclerodanes 30:709 Furodysin 21:361 (-)-Furodysin 6:28 from Dysidea species 6:28 oxy-Cope rearrangement in 6:28,29 synthesis of 6:28,29 Furodysinin 6:28;25:815 from Dysidea species 6:28 oxy-Cope rearrangement in 6:28,29 synthesis of 6:28,29 Furodysinin lactone thioacetate 25:815 Furofoline II 13:371,372,374 Furofuran lignans 26:200,201 ;30:594 antiplatelet activity of 30:594 Furofurans 24:756-762 Furoguaiacidin diethyl ether 17:325 synthesis of 17:325 Furohyperforin 30:611,613 structure of 30:613 Furohyperforin hydroperoxide 30:611, 613 as artifacts 30:611 structure of 30:613 2-Furoic acid 30:456 Furo-indoloquinolizine derivative 8:285 Furolabda-6,8-dien-17-oic acid 30:712 structure of 30:712 Furolabda-7-en- 17-oic acid 30:713 structure of 30:713 Furopelargone 23:815 Furopelargone A 23:813 Furopelargone B 23:813 Furopyridones 8:288,289 Furosin 30:208 analgesic effect of 30:208 Furospongolide 25:698 Furostane glycosides 17:136 Furostane-type saponin 21:675
Furostanol glycosides 17:116,135; 21:636 Furostanol saponin 21:636 Furst-Plattner effect 19:357 Furuta 29:466 pyranoid carbasugars synthesis by 29:466 2-Furycarbinol 19:464,19:473 Furyl alcohol 16:655 Furyl carbinols 16:639,648,651 2-(2-Furyl)-3-(5-nitro-2furyl)acrylamide 21:584 23-Furylbrassinolide 19:280 2-Furylcarbinols 19:463-509 Furylfuramide 21:584 2-Furyllithium 30:458 Furyllithium reagents 11:440 Fusarentin-6,7-dimethyl ether 15:387 Fusarentin-6-methyl ether 15:387 Fusaria sp. 24:942 fusicoccins from 24:942 Fusaric acid 6:219,220;21:587 Fusarin A,C,D,E,F 13:526,527 Fusarin C 9:203,204,214,215 Fusarins 6:250,252 biosynthesis of 6:250,252 from Fusarium moniliforme 6:250,252 Fusarium 6:201-259;9:201-208;13:519, 524-529;21:213,216,227,233 ;22:57; 26:464,482;27:158 Fusarium acuminatum 9:204,213; 13:535 Fusarium avenaceum 9:204,205, 213,214;13:526,535 Fusarium compactum 13:536;29:575 Fusarium crookwellense 9:205;13:526 fusarin C from 13:526 Fusarium culmorum 4:250,204-208, 212,648;13:519,520,526;27:225,382 Fusarium equiseti 9:204;13:543, 545;28:121 HIV inhibitory activity of 28:121 Fusarium graminearum 9:204-208,216, 524,543 Fusarium heterosporum 29:111 Fusarium larvarum 15:381,386
334
Fusarium lini 18:807
monohexosylceramides from 18:807 Fusarium merismoides 9:204 Fusarium moniliformes 9:203205,214,215;13:524,526,530 Fusarium nygamai 13:530 Fusarium oxysporum 9:204;21:189,196, 199,210,217,223,232 ;23:139,355 ;25: 293,295,296,299,305,311,312,313, 317,319,320,322 Fusarium oxysporum f. sp. cucumerinum 9:238 Fusarium poae 9:204,314,315,526 Fusarium proliferatum 13:530 Fusarium roseum 13:543 Fusarium sambucinum 9:204; 13:526,543; 25:317 Fusarium semitectum 9:204 Fusarium solani 9:204;25:303,305, 307,314,316,317;26:404,405,418 monohexosylceramides from 18:807 Fusarium sporotrichioides 6:247,204, 205,208-213;13:526 Fusarium subglutinans 13:530 Fusarium toxins 9:201-208 Fusarium tricinctum 9:205 Fusarium udum 21:240 Fuscoside B 29:103 andalusol as 29:109 andrographolide as 29:109 cafestol as 29:108 kahweol as 29:108 sarcophytol A as 29:104 structures of 29:105 Fused azacycloundecine systems 6:496 synthesis of 6:496 cis-Fused bicyclic furanone 29:452 carbafuranose synthesis from 29:452 cis/trans-Fused decalones 14:460 Fused eight-membered ring systems 6:468-474 Fused eleven-membered ring system 6:494-497 Fused lactone nucleoside synthesis 4:252
Fused nine-membered ring system 6:472-482,483-493 Fusicoccin 25:374 Fusicoccum amygdali 15:385 Fusicoplagins A-D 2:81 Fusidic acid 21:237;22:247 Fusidienols 24:443 Fusidium coccineum 21:231 Fusioccane 3:93,94 Fusion reactions 4:236,38 Fusion technique 4:222 Fusobacterium nucleatum 4:195 Futoenone 8:159;26:245 synthesis of 8:159 Futoquinol 8:169,170;26:245 synthesis of 8:169,170 G-90 30:841 as ot plasminogen activator 30:841 (+)-GAI 6:178-181 synthesis of 6:178-181 GAI2 6:172,194 GAI2 aldehyde 6:171,172,186 GAI3 72,187 GAi9 6:188 biogenesis of 6:188 from bamboo shoots 6:187 GA24from 6:188 GA44 from 6:188,189 GA20 6:186 from GAs3 6:186 GA24 6:188,189 GA3 methyl ester 8:117 synthesis of 8:117 GA31 8:117 synthesis of 8:117 GAg2 6:191-193 synthesis of 6:191-193 GA36 6:172,189 GA37 6:184,185 synthesis of 6:184,185 GA38 6:184,185 synthesis of 6:184,185 GA4 6:172,176,168,202,209 (+)-GA4 6:178-181 synthesis of 6:178-181 GA44 6:186,188
335 GAs3 6:186,188 GA69 6:191 GA7 6:172,186,195,201,202,209 GAT0 6:191 GA9 6:172,194 GA9 methyl ester 6:204 GABA (,/-aminobutyric acid) 1:89; 13:514;21:84 ;25:30,536,537;30:627, 782,783,787 effect on blood pressure 30:783 effects of glutamic acid decarboxylase (GAD) 30:783 effects of hyperforin inhibitor 30:627 hypotensive effect of 30:782 in spontaneously hypertensive rats 30:783 in systolic blood pressure in SHR 30:783 synthesis of 13:514 GABA agonist 25:528 GABA antagonists 21:69 GABA gated Cl-channels 25:528 GABA receptors 21:69,95;25:531 GABA transporter 25:537 GABAA 21:672,673;22:666 GABAA receptor 21:14,19,101,269,270; 25:529,895 ;30:203 interaction with ginseng 203 GABAB 21:14,672;22:666 GABAB receptor 21:20;25:530; 30:203,787 effect in SHR 30:787 G-protein-linked receptor type 25:530 interaction with ginseng 30:203 GABA-benzodiazepin-chloride channel receptor 21:672 (+)-Gabaculine 13:509,510 synthesis 13:509,510 GABA-ergic neuroreceptors 21:5 GABA-ergic receptor 21:68 Gabapentin 22:508 Gabunamine 5:124 Gabunine 5:124 G-Actin 22:33 GADPH 21:229 Gaeumannomyces graminis 25:304
Gaeumannomyces graminis vat tritici 21:186,196,199,204,210 GaINAcfll --~4[NeuAc a2--~3)Galfll 4Glcfll--+' 1 Cer 5:488 Gajasmin 16:298 [3-Galabioside 14:149 Galactal 7:59 [3-D-Galactan 5:275,278,279 Galactan 5:276,300 Galactinol 18:396 Galacto-configuration 4:147,148 D-Galacto-hexodialdopyranose 4:163,164 Witting olefination of 4:163,164 Galactomannan 5:279,286,289,290, 292,293,295,301,302,306-309,312, 313,325;26:148;27:511 Galactonic acid 8-1actone 2:163 Dc~-D-Galactopyranose 27:511 D-Galactopyranose 6:376 Galactopyranose 7:47 Galactopyranosides 5:657 [3-D-Galactopyranosides derivatives 7:52-54 3-O-[3-D-Galactopyranosyde 27:477
4-S-~-D-Galactopyranosyl-4-thio-Dgalactose 8:335 4-S- [3-D-Galactopyranosyl-4-thio- s-Dgalactopyran-oside 8:335 4-S-[~-D-Galactopyranosyl-4-thio-Dglucose 8:335 6-S-[3-D-Galactopyranosyl-6-thio-Dglucose 8:338,339 synthesis of 8:338,339
3-O-~-D-Galactopyranosyl-D-galactose
7:137 4-O-c~-D-Galactopyranosyl-~-Dgalactopyranoside 14:149 Galactose 7:153,158,294;22:312 D-Galactose 4:29,130,197,198,'27:506 L-Galactose 4:197,198 Galactose oxidase 7:71,72 Galactose prodrugs 21:161 biological behaviour of 21:161 synthesis of 21:161 Galactose rich acidic glycoprotein 25:453,454
336
D-Galactose-molybdate complex 15:429 ot-Galactosidase 7:38,39,567,568; 21:161,167 [3-Galactosidase 7:40;10:470,471, 567,568;22:739;25:210 inactivation by [3-galactoside analogue 7:40 inhibition by aminoglycopyranoses 7:47 inhibition by conduritol C cisepoxide 7:38 inhibition by conduritol C transepoxide 7:38 inhibition by [3-galactosyl amines 7:44 inhibition by nitrophenylthiogalactoside 7:48 Galactosidases 7:39,50,52,65 fromE, coli 7:39,50,52,65 Galactosidasic 24:999-1001 enzymatic activity 24:999-1001 ot-D-Galactosidation 14:150 of methyl 2-O-benzyl-4,6-Obenzylidene- 13-D-galactopyranosides 14:150 [3-Galactoside analogue 7:39,40 13-Galactoside derivatives 7:52,55 Galactosides 7:48 [3-Galactosides 8:315 Galactostain 7:41,42,267 from Streptomyces lydicus 10:542 mammalian [3-galactosidase inhibitor of 10:542 Galactostatin lactam 10:543,550 ot-D-Galactosyl prodrug 21:176 Galactosyl transferase 10:468,500,501 [3-Galactosylation 10:470 t~-Galactosylceramides 18:460 6-O-[3-D-Galactosyl-D-glucose 27:521 [3-(1-4)Galactosyltransferase 10:484 D-Galacturonic acid 4:198;6:363;7:181; 27:506 Galacturonorhamnans 26:1156 Galangin 22:328;25:541;26:752 Galanin effect 27:799,800 Galanin receptor antagonists 27:799
Galanolactone 23:801 Galanthamine 4:3,4,13,21;20:325,346, 370,385 ;21:52,84,102,748 ;22:5,30; 26:614 Galanthine 26:614 Galantinic acid 12:487 Galaxura marginate 25:704 Galeon 17:371 (+)-Galeon 26:899 Galeopsis angustifolia 25:251 Galeopsis ladanum L. 22:521 Galinum sinaicum 26:220 bis-glucoside derivatives from 26:220 Galiosin 26:657 Galipine 3:385,386 Galium 4:400;26:631 Galium sylvaticum 22:521 Galium verum L. 22:521 for epilepsy and hysteria 22:521 Galleria mellonella 22:384 Gallic acid 23:537,551,740,746; 26:359,798;28:280;30:208 analgesic effect of 30:208 derivatives of 30:208 design of 30:208 structure of 28:280 Gallic Wars 19:140 Gallicin 7:230 Gallic-p-coumaric acid 26:359 Gallic-sinapic acid 26:359 Gallocatechin 22:362;23:743,749; 25:943;26:748 (+)-Gallocatechin 23:745 Gallocatechin 3-gallate (flavan-3-ol) 29:585 effects on proteasome CHYlike activity 29:585 Gallocatechin-3-gallate 23:743 Gallotannins 23:750,752 Galloylation 21:543 Gal-N cyctotoxicity 21:656 Galphimia glauca 22:521 for epilepsy 22:521 Galpinone 20:276 Galsky potato disc method 9:386 Gambierdiscus toxicus 21:300;25:730 Gambirtannine 1:100,101 Gambusia affinis 21:365
337 Gametocyte 25:329 Gamma aminobutyric acid 21:10,19 Gamma linoleic acid 13:659 Gamma-elimination 8:420 Gancaonin C 28:228 biological activity of 28:228 Gancaonin E 28:228 biological activity of 28:228 Gancaonin G 28:228 biological activity of 28:228 Gancaonin H 28:228 biological activity of 28:228 Gancaonin I 28:228,243 anti-Helicobacter pylori activity of 28:243 anti-microbial activity of 28:224 biological activity of 28:228 Gancaonin O 28:228 biological activity of 28:228 Gancaonin P 28:228 biological activity of 28:228 Gancaonin Q 28:228 biological activity of 28:228 Gancaonin R 28:226 anti-human immunodeficiency virus (HIV) activity of 28:226 biological activity of 28:228 Gancaonin S 28:228 biological activity of 28:228 Gancaonin U 28:228 biological activity of 28:228 Gancaonin V 28:228 biological activity of 28:228 Gancaonin Y 28:228 biological activity of 28:228 Gancaonol B 28:224,243 anti-Helicobacter pylori activity of 28:243 anti-microbial activity of 28:224 Gancaonol C 28:243 anti-Helicobacter pylori activity of 28:243 Ganciclovir 21:698;24:474,486 as anti-viral agent 24:474,486 synergistic interaction with 21:698 Ganervosin A 15:138,146,155,173 Ganervosin B 15:141,173
Ganglionic-type nicotinic receptor 21:95 Ganglioside 18:486,786,788 Ganglioside GM3 16:88 Ganglioside GM4 8:343-344 Ganglioside GM5 18:486 from Anthocidaris crassispina 18:486 Gangliosides 7:307,10:459 Ganoderic acid F (12-acetoxy3,7,11,15,23-pentaoxolanost-8en-oic acid) 30:64 13C-NMR of 30:64 effects of 30:63 effects on hemoglobin 30:63 H-NMR of 30:64 IR data of 30:64 MS analyses of 30:64 structure of 30:64 Ganoderma japonicum 23:115 Ganoderma lucidum 22:132;23:126,
133;26:449;30:56,58,60
antimetastatic effect of 30:58,60 antitumor effect of 30:58 effect on blood glucose 30:58 in treatment of arteriosclerosis 30:58 in treatment of arthritis 30:58 in treatment of bronchitis 30:58 in treatment of cancer 30:58 in treatment of diabetes 30:58 in treatment of hyperlipidemia 30:58 in treatment of hypertension 30:58 triterpenoid fractions of 30:60 triterpenoid from 30:56 Garaniol 20:20,31 Garbanzol 26:745 Garcigerrin A 7:444,445,457 Garcinia 7:444;22:658 Garcinia cambogia 22:658 Garcinia cowa 26:805 Garcinia gerrardii 7:444,445,457 Garcinia huillensis 22:658 Garcinia indica 22:658 Garcinia livingstonei 22:659 Garcinia mangostana 4:382,384; 27:902;29:573
338
Garcinia mannii 22:658 Garcinia ovalifolia 22:658,659 Garcinia polyantha 22:658 Garcinia spicata 5:757,758 Garcinia staudtii 22:658 Garcinia subelliptica 22:660 Garcinia thwaitesii 5:757,758 Garcinia xishuanbannanensis 22:658 Garcinol 22:658 Garcinone A 4:382,284 Gardenia cramerii 5:756,757 Gardenia fosbergii 5:756,757 Gardeniajasminoides Ellis 16:298 Gardenia sp. 5:756,757 Gardeniae 21:124 Gardenin A (flavone) 29:572 effects on HIV- 1 protease 29:572 Gardenin B 5:654 Gardenin D 7:227 Gardenoside 16:298 Gardneria nutans 15:491 Gardnerine 15:491 from Gardneria nutans 15:491 Gargugamblins 17:370 Garjasmidin 16:298 Garjasmin 16:298,299 Garlic 23:455,467 supercritical fluid extraction of 23:467 Garlic bulbs 23:460 Garlic clove 23:462 cross-section of 23:462 Garrya 6:174 Garryine 3:435 synthesis of 3:435 Garsubellin A 22:660 Garuga gamblei 17:370, Garuga pinnata 17:370,375-376;26:899 Garuga sp. 17:375;26:899 Garugamblins 17:378 Garugamblin- 1 17:386,389 Garugamblin-2 17:386 Garuganin 26:111,899 Garuganins 17:370,378 Garuganin III 17:386 synthesis of 17:386 Gas chromatography 21:536,578 Gas phase B3LYP calculation 30:549
GASPE spectrum 5:145 Gassman oxindole synthesis 3:320 Gasteria 22:580 Gasteromycetes 9:202 Gastric acid secretion 21:701 inhibitory effect on 21:701 St-4Gastric carcinoma 19:298 Gastric H+,K+-ATPase 25:612 Gastric hemorrhagic erosions 22:443 Gastric tubing 27:314 for gastrointestinal absorption 27:314 Gastrin receptor 25:611 Gastrin releasing peptide 27:800 Gastritis 17:137 Gastrodia elata 25:529 Gastrointestinal cancer 1:275 Gastrointestinal depression 30:799 due to analgesic alkaloid 30:799 Gastrointestinal diseases 30:56,691,747 use of Maytenus amazonica for 30:691 Gastrointestinal disorder 25:607 effect offlavonoids 25:607 effect on gastrointestinal disorder of 25:607,615 Gastrointestinal hormones 27:794 Gastrointestinal peptide-hormones 27:797 Gastrointestinal toxicity 27:436;28:559, 560-562;30:56 by doxorubicin 28:562 chitosan inhibitory effect on 28:561 due to cancer drugs chemotherapy 30:56 of 5-fluorouracil (5-FU) 28:560 of bilobalide 28:171 of chitosan 28:559 of fish oils 28:559 Gastroprotective agents 25:614 Gaucher's disease 7:39 Gaudichandioside A 27:14,24,25; 30:734 against certain cancer cells 30:734 medicinal uses of 27:447 Gaudichaudioside B 15:22 Gaudichaudioside C 15:22
339
Gaudichaudioside F 15:22;25:251 Gaudichaudol 25:269 Gaudichaudols A-C 30:734 structure of 30:734 Gaultheria procumbens 21:619 GB-2a 5:758 GB-I 5:758 GB-Ia 5:758 GC-mass spectrometry 21:579 GC-MS 21:579,583,584,607 G-coupled proteins 30:808 phosphorylation of 30:808 GDIBOA 27:188,209 synthesis of 27:210 GDIM2BOA 27:188,209 synthesis of 27:210 Gedunin 7:190,191 Geigeria burkei 14:450 Geigeria sp. 20:10 Geigerin 20:10 Geissman-Waiss lactone 13:484,485 Geissochizol 5:73,126;9:171 Geissoschizine 1:21,31 ;5:126,520,171 (+)-Geissoschizine 13:490,491 Geissoschizine-type alkaloids 5:71,73 (+)-3-epi-Z-Geissoschizol 14:722-724 (+)-Z-Geissoschizol 722-724 Geissoschizoline 1:34,38,39,41,42, 46,48 Geissoschyzine 26:97 Geissospermum laeve 1:124 Geissospermum vellosii 1:124 Geiwiz and Hasslinger 29:185 pisiferic acid synthesis by 29:185 Gel electrophoresis 2:19,114 Gelatinasic 24:999-1001 enzymatic activity 24:999-1001 Geldanamycin 5:434,592;21:420,435; 23:54,72,89,90,91 absolute configuration of 23:90 ansa moieties of 23:91 biosynthetic units of 23:90 related compounds 23:72 Gelliusins A,B 21:72 Gelonium multiflorum 9:265 Gelsamydine 15:483-486 Gelsedine 15:481,482 Gelsedine-type alkaloids 15:481-483
Gelselegine 15:483,484 Gelselegine-type oxindole alkaloids 15:483-485 Gelsemamide 15:472,473 Gelsemicine 15:482 Gelsemide 7:441;15:478,479 Gelsemine N-oxide 15:479 Gelsemine-type oxindole alkaloids 15:478-481,504,505 Gelsemium 15:465-515 Gelsemium elegans 15:466,472,473 akuammidine from 15:466 gelsemamide from 15:472,473 humantenine from 15:472 koumine from 15:475,476 11-methoxygelsemamide from 15:472,473 16-epi-voacarpine from 15:469 Gelsemium rankinii 15:465 Gelsemium sempervirens 1:125,465467 Gelsemoxonine 15:481,482 Gelsenicine 15:481,482 Gelsevirine 15:479 from Gelsemium elegans 15:479 from Gelsemium rankinii 15:479 from Gelsemium sempervirens 15:479 Gemin A 23:397 Gemin B 23:397 Genanial 25:133 Genatiana macrophylla 25:476 Gene experession control 5:580,581 Gene expression 30:373 Gene SLC18A2 30:380 role in vesicular monoaminetransporter type 2 (VMAT2) 30:380 General skeleton 26:190 of lignans 26:190 Generation 27:64,69-71,73,74,75,78, 79,83 of 13-oxo-9,11-octadecadienoic acid 27:73 of 13-oxo-9-hydroxy- 10octadecenoic acid 27:73 of 9S-hydroperoxy 10E, 12Z, 16Zoctadecatrienoic acid from 27:70,71
340 ofjasmonic acid 27:64,71-73 of 16S-hydroperoxy-9Z, 12Z, 14Eocta-decatrienoic acid (16SHPOTE) 27:70 of 13-hydroperoxy-9Z-11Eoctadecaenoic acid 27:69-71 of 2E-4-hydroperoxy-2-nonenal (4-HNE) 27:74,75,83 of 16-hydroperoxy- 10,12,14octa-decatrienoic acid 27:71 of LO" radicals 27:78,79 of traumatic acid 27:75 of epoxyaldehydes 27:82 of salicylic acid 27:63 Genes 4:267 synthesis of 4:267 Geneserine 21:84 Genetic duplication 30:370 of ancestral gene 30:370 Genetic mapping 9:606,607 (+)-Genipin 16:290,20:56 Genipin 7:441 Genista cinerea 27:272 Genista rumelica 22:428;25:612 luteolin, luteolin-7-glucoside and genistein from 22:428 Genistein 22:424,428,458,460,495; 25:544,546,593,613;26:750,751,754, 757,760,802,803 ;27:843,844 Genistein (4', 5,7-trihydroxy-isoflavone) 29:577 effects on aminopeptidase N 29:577 Genital warts 30:405 Genkwanin 26:219;30:727 as chemopreventive agent 26:219 structure of 30:727 Genotoxic agent 30:316 from Rubia tinctorum L. 30:316 Genotoxicity assays 26:675 Gentamicin C2 4:188 Gentamycin C la 115 Gentamycin X2 14:145 Gentiana compestris 22:521 Gentiana crassicaulis 22:521 for convulsions 22:521 Gentiana dahurica 22:521 for convulsions 22:521
Gentiana decumbens L. 22:521 for convulsions 22:521 Gentianafetisowii Regel 22:521 for convulsions 22:521 Gentiana macrophylla 22:521 for convulsions 22:521 Gentiana sp. 5:651;23:564;25:471 Gentiana tibetica King 22:521 for convulsions 22:521 Gentiana wutaiensis 22:522 for convulsions 22:522 Gentianaceae 25:471 Gentianine 6:528,529,444 Gentianine derived alkaloids 6:528,529 Gentianine series 6:522 Gentiobiose 8:349;15:436;25:968 Gentiopicroside 7:442;25:471 effect of gentiopicroside 25:471 serum ALT activity of 25:471 Gentisic acid 21:617 Gentosamine 14:50 Genus Astragalus 27:251,443,446 abrisapogenol B from 27:443,453 astragenol from 27:449 complogenin from 27:453 9,19-cyclo-5(x,9[3-1anostane from 27:447 cyclocanthogenin from 27:448 cycloalpigenin from 27:452 cycloalpigenin B from 27:449 cycloalpigenin C from 27:449 cycloalpigenin D from 27:449 cycloasgenin A from 27:449 cycloasgenin B from 27:558 cycloasgenin C from 27:448 cycloastragenol from 27:449 cyclogalegenin from 27:450 cycloorbigenin A from 27:452 cycloorbigenin B from 27:452 cyclopycnanthogenin from 27:450 dasyanthogenin from 27:451 3-dehydrocycloasgenin from 27:448 dihydroycloorbigenin A from 27:452 glycyrrhetic acid from 27:453 medicinal uses of 27:447
341
oleanolic acid from 27:453 oxytrogenin from 27:453 quisvagenin from 27:450 sapogenin from 27:448 sapogenin II from 27:453 saponins from 27:446 soyasapogenol B from 27:453 terpenoid sapogenins from 27:446 Genus Bupleurum L. 27:660 Genus Dorstenia 29:761 analgesic activities of 29:761 anti-infective principles from 29:761 anti-inflammatory activities of 29:761 anti-oxidant activities of 29:761 anti-rheumatic remedies from 29:761 anti-snakebite principles from 29:761 as chalcone source 29:761 as flavanone source 29:761 as flavone source 29:761 as flavonol source 29:761 as geranyl-substituted coumarin source 29:761 as prenyl-substituted coumarin source 29:761 chemistry of 29:761 cytotoxic activities of 29:761 5,3'-digeranyl-3,4,2',4'-tetrahydroxychalcone from 29:761 O-[3-(2,2-dimethyl-3-oxo-211furan-5-yl)butyl]bergaptol from 29:761 7,8-(2,2-dimethylpyrano-4'methoxyflavanone (dorspoinscttifolin) from 29:761 3 ', 4 '-( 2,2-dimethylp yrano-6prenyl-7-hydroxyflavonone from 29:761 ethnomedical information of 29:762 fig family of 29:762 in skin diseases 29:762 mulberry family of 29:762 occurrence of 29:761
pharmacology of 29:761 to treat rattlesnake bites 29:765 Genus Dorstenia (Moraceae) 29:761 analgesic activities of 29:761 anti-infective principles from 29:761 anti-inflammatory activities of 29:761 anti-oxidant activities of 29:761 anti-rheumatic remedies from 29:761 anti-snakebite principles from 29:761 cytotoxic activities of 29:761 in skin diseases 29:762 pharmacology of 29:761 to treat rattlesnake bites 29:765 Genus Hernandia 30:563-580 (-)-laetine from 30:564 (+)-actinodaphnine from 30:563 (+)-corytuberine from 30:563 (+)-hemagine from 30:563 (+)-hemandaline from 30:563 (+)-hemovine from 30:564 (+)-isoboldine from 30:564 (+)-isocorydine from 30:564 (+)-laurotetanine from 30:564 (+)-magnoflorine from 30:564 (+)-N-formyldehydroovigerine from 30:563 (+)-N-formylnornantenine from 30:563 (+)-N-formylovigerine from 30:563 (+)-N-hydroxyhernangerine from 30:564 (+)-N-me thyl-6,7- dime tho x yi soquinolone from 30:564 (+)-N-methylactinodaphnine from 30:564 5,6-dimethoxy-N-methylphthalimide from 30:563 6,7- dimetho xy-N-methylis oquinoline from 30:563 7-formyldehydrohernangerine from 30:563 7-formyldehydronornantenine from 30:563 7-formyldehydroovigerine from
342
30:563 7-hydroxy-6-methoxy- 1methylisoquinoline from 30:564 alkaloids from 30:563 antiplatelet aggregation effect of 30:560 atheroline from 30:563 backebergine from 30:563 benzenoids from 30:567 constituents of 30:563-570 dehydrohernandaline from 30:563 demethylsonodione from 30:563 hernandonine from 30:564 hernangerine from 30:564 hernanymphine from 30:564 isoindole from 30:563 isoquinoline from 30:563-567 laetanine from 30:564 laudanosine from 30:564 lignans from 30:567 lindearpine from 30:564 monoterpene from 30:569 N-(N-methylcarbamoyl)-Omethylbulbocapnine from 30:564 N-formylnornantenine from 30:563 N-hydroxyovigerine from 30:564 N-methylcorydaldine from 30:564 pyridine from 30:567 sterols from 30:569-570 Genus Hypericum 30:607,619 hypericin from 30:607 isohypericin from 30:607 pseudohypericin from 30:607 xanthones from 30:619 Genus Mortonia 23:665 Genus Morus 28:200 anti-inflammatory activity of 28:200 anti-tussive activity of 28:200 anti-pyretic activity of 28:200 Genus Ononis 30:138 resorcinolic from 30:138 Genus Pseudomonas 29:329 Genus Tanacetum 27:547
Genus Teucrium 23:591-648 biological evaluation of 23:591648 chemical evaluation of 23:591648 Geodia 25:768;26:488,1210 Geodia cydonium 25:718 Geodiamolide A 25:769 Geodiamolide C 25:769 Geodiamolide D 25:769 Geodiamolide E 25:769 Geodiamolide F 25:769 Geodiamolides 25:757,768 Geodiamolides A-T 25:768 Geosmin 26:353,354 Geothelphusa dehaai 19:647 Geothricum penicillatum 13:302 Geotrichum candidum 23:349;26:673 Geotrichum louberi 26:673 Geotrichum penicillatum 25:129 Gephyrotoxin 1:23,223,287,288,292, 385-389;4:606;6:449;7:11,10:186, 453;16:453;21:56 3-Gerandyloxy-6-methyl- 1,8dihydroxyanthrone 7:418-420,424 Geranial 13:333,17:433 Geranic acid 20:5;25:132,133,134 Geranii 27:413 corilagin from 27:413 Geranii herba 27:413,415 biological activity of 27:413,415 Geranii herba 27:415 Geraniin 27:840;29:572;30:208 analgesic effect of 30:208 effects on HIV-1 protease 29:572 Geraniol 7:100,101,104,105,107,108, 116,117,125,19:83;20:5;21:589,590, 612;22:392;25:125,132,134,136138,140,142,143,163,165;28:406,42 6;29:83 acaricidal properties of 28:406 activity in ODC assay system 29:83 activity in RAS assay system 29:83 as bioactive monoterpenoid 28:426 E-Geraniol 8:77
343 Z-Geraniol 8:77 Geraniol acetate 10:9,14 Geranium 29:572 Geranium macrorhizum 5:679 Geranium oil 25:132 Geranium thunbergii 17:421,428, 433;27:413 Geranyl acetate 15:227;25:136,164 from Eremophila abietina 15:227 Geranyl acetone 6:60 Geranyl bromide 4:386,386,391 Geranyl diphosphate 7:324;11:219-221 (+)-bornyl diphosphate from 11:219-221 (1R)/( IS)-[ 1-3H]Geranyl diphosphate 11:220,221 Geranyl geraniol 25:239 Geranyl geranyl phosphate 11:4 Geranyl geranyl pyrophosphate 11:24 Geranyl hydroquinone 5:440 Geranyl linalool 25:254 Geranyl linalyl pyrophosphate coaplyl PP 25:239,240 3-Geranyl-2,4,6-trihydroxy-benzophenone (phenolic ketone) 29:571 inhibition of Candida albicans aspartic protease 29:571 (5)-(+)-Geranylacetol 25:163,164 Geranylacetol 25:168,169 (E)-Geranylacetone 28:406 acaricidal properties of 28:406 8-Geranylapigenin 28:234 synthesis of 28:234 Geranylated monochalcones 29:774 5,3 '-(3,7-dimethyl-2,6- octadienyl)-3,4,2',4'-tetrahydroxychalcone as 29:775 4'-geranyloxy-4,2'-dihydroxychalcones as 29:775 poinsettiflin B as 29:774 proropensin as 29:774 Geranylfarnesol 6:111 Geranylgeraniol 15:253,20:26,28,30 Geranylgeranyl diphosphate 5:701; 7:321,322,324,325,327,330,348,351; 21:721 ;25:237,240,244 (E,E,E)-Geranylgneraniol derivatives 1:662-665
trans-Geranyllinalool 20:590 Geranyllinalool isonitrile 21:330 3-Geranyloxyemodin 7:418-420 9-Geranyl-a-terpineol 30:615 structure of 30:615 Gerinimum genera 27:755 Gerlach's procedure 6:542,543 (7S)-Germacra-1 ( 10)E,4( 15)-dien2[3,5cz,6~-triol 29:88 activity in TPA assay system 29:88 activity in PLA assay system 29:88 (7S)-Germacra-4( 15)Z,9-diene- 1or,2[3, 6[3-triol 29:88 activity in TPA assay system 29:88 Germacradiene 8:59 Germacradienolides 7:210 cis, cis-Germacradienolides 7:210,211 Germacrane 6:15,607;7:209,211, 212,214,216;29:88 activity in CRG assay system 29:88 activity in HPT assay system 29:88 curdione as 29:88 dehydrocurdione as 29:88 germacrone as 29:88 neocurdione as 29:88 Germacrane D 30:607,715,722 structure of 30:722 Germacrane lactone 8:195-201 Germacrane- 12,8-olides 7:231 Germacranolides 2:280,210,211 ;27:560 6,12-Germacranolides 24:806 Germacrene D 9:531,534;26:409, 413;27:573 Germacrene isoprenologue 15:278 (-)-Germacrene-D 6:540 Germacrenes 23:160 Germacrenoid structure 6:538,539 Germacrolides 7:210 Germacrone 8:178;23:825,833; 25:172,173 synthesis of 8:178 Germanocrenolide 26:808 Germination 9:219-248
344
Germination inhibitor 1:684 synthesis of 1:684 Gernaiol 25:132 Gernayl geranyl pyrophosphate 25:248 Gerrardine 7:192 Geseneriaceae 25:251 Gestogens 17:623 semi-synthesis of 17:623 Geumjaponicum 23:397;29:574 GF-109203 X 12:389 Ghosez cyclization 26:1230,1231 8-C-Ghycosylflavones 5:644 Giardia intestinalis 26:1063 C20Gibberelins 6:184-190 Gibberella cyanea 25:162,166 Gibberella fujikuroi 8:115,117; 24:938,942,954 ;25:253,255 diterpenes from 24:938 gibberellins from 24:938 Gibberella gaminis var. avenae 25:304,305,306,308,310 Gibberella pluicaris 25:293, 305,307,311,317,319 Gibberellane 25:241 Gibberellenic acid 6:199;25:245 as gibberellin 6:171,172,181-184 as gibberellin A3 6:171,172 from gibberellic acid 6:199 gibberellenic acid from 6:199 growth effect on root culture 17:425 total synthesis of 6:181-183 synthesis of 8:116 Gibberellic acid (GA3) 6:181-183,209, 100;7:100;8:115-120 C20 gibberellins from 6:186190 from Gibberella fujikuroi 6:172,186 in gibberellic acid 6:171 Gibberellins 6:171,194-209;8:115-135; 22:67,247 ;25:367,657 ;27:305 antheridiogens from 6:171,194209 partial synthesis of 6:186, 194-209 from gibberellic acid 8:115 homonuclear 8: ~H-IH-shift 8:117
mass spectrum of 8:117 synthesis of 3:435;8:115-137 Gibberellin A7 6:197-201 Gibberellin oxo esters 8:128 Gibberellin thioanalogs 8:123-127 Gibberellin-7-aldehydes 8:128 Gibberellins AI,A3,A4,Av,A9 7:188 Gibberellins GA4 8:115,119,120 Gibberellins GAs5 8:121,122 from 1[3-azido-3[3-hydroxy compound 8:121,122 synthesis of 8:119,121,122 Gibberellins GAs7 8:121,122 from GA3 8:121,122 synthesis of 8:115,121,122 Gibberellins GA60 8:121,122 from GA3 8:122 synthesis of 8:115,121,122 Gibberellins GA7 8:119 from GA3 8:119 synthesis of 8:115,119,120 allo-Gibberic acid 8:117 synthesis of 8:117 Gibberic acid 8:117 synthesis of 8:117 Gibbonsia elegans 17:94;25:787 Gibbs test 22:489 Giffordene 21:306 Giffordia mitct~ "ae 21:306 Gigantecin 9:3~,5-397;17:277;18:221, 222 Gigantenone 6:554-556 (+)-Gigantenone 6:555,556 Gigantetronenin 18:221 Gigartina skottsbergii 30:402 carrageenans from 30:402 Gilben's reagent 26:1245 Gilman reagent 22:206 Gilvocarcin 10:343,374 Ginamallene 5:369,370 Gindarine 21:56,57 Gingenoside Ro (chikusetsusaponin V) 24:147,148 Ginger glycolipid A 23:851 Ginger glycolipid B 23:851 Gingerenone A 23:849 Gingerenones A, B and C 17:378 (6)-Gingerol 23:818 (8)-Gingerol 23:818
345 Gingerol 9:321,328;23:846; 24:900;26:475 as an accelerator of the motility of digestive organs 24:900 as an antiemetic agent 24:900 biosynthesis of 23:848 effect of gingerol analogues on NA-contraction 24:902 effect of gingerol analogues on PGF2a- contraction 24:902 related compounds 24:900-902 Gingkolides 13:659 Ginkgo biloba L. 9:317,321,323,659, 660;21:591 ;24:297 ;26:929;28:165, 170;29:571 anti-depressant effect of 28:177 anti-oxidant activity of 28:179 anti-stress effects of 28:177 amentoflavone from 28:166 apigenin from 28:167 biological activities of 28:165 3 '-O-methylmyricetin-3-Orutinoside from 28:167 5'-methoxybilobetin from 28:166
Ginkgol 9:323 Ginkgolic acid 5:826-828,355,436,317; 21:590 Ginseng 13:660;25:182;30:203 activity in chronic pain model 30:203 as analgesic 30:203 interaction with bradykinin B2 receptor 30:203 interaction with GABAA receptor 30:203 interaction with GABAB receptor 30:203 interaction with neurokinin NK~ receptor 30:203 Ginseng root 30:203 use in abdonminal pain 30:203 use in chest pain 30:203 use in folk medicine 30:203 use in neuralgia 30:203 use in pain 203 use in toothache 30:203 Ginseng rubra 21:675 ginsenosides from 21:675
Ginseng saponins 21:651 ;30:203 action of 30:203 Ginsenoside Rb~ 21:645,653,667,669, 670;25:958;27:859,860 Ginsenoside Rb2 21:638,645,653,666, 669,670 Ginsenoside Rb3 21:669 Ginsenoside Rg~ 24:146;27:424 biological activity of 27:424 Ginsenoside Ro 21:651,657,670 Ginsenoside Ryl 25:958 Ginsenoside-Re 21:645,653,669,670 Ginsenoside-Rg~ 21:645,653,669-671 Ginsenoside-Rg2 21:670,671 (20S)-Ginsenoside-Rg2 21:672 20(R)-Ginsenoside-Rg3 21:638 20(S)-Ginsenoside-Rg3 21:638 Ginsenosides 15:191;30:203 action of 30:203 effect on central nervous system 30:203 effect on nociception 30:203 effect on spinal region 30:203 effect on supraspinal region 30:203 voltage-sensitive calcium channels blockade by 30:203 Ginsenosides-Rc 21:653 Ginsenosides-Rd 21:645,653 Gissampelos insularis 25:478 Gitaloxigenin 15:362 Gitaloxin 15:362 Gitoxigenin 15:362 Gitoxin 15:362 6-Glucuronide 22:10,24 Gizzerosine 1:679,780 synthesis of 1:679,780 GL-311 26:162 used for anticancer treatment 26:162 Glabranin 28:228 biological activity of 28:228 Glabrene 28:224,228 anti-Helicobacter pylori activity of 28:241 anti-microbial activity of 28:62,224,228,257,293 biological activity of 28:228
346
Glabridin 27:846;28:228,241 anti-Helicobacter pylori activity of 28:241 anti-microbial activity of 28:224 biological activity of 28:228 Glabrocoumarone A 28:229 biological activity of 28:229 Glabrol 28:228 biological activity of 28:228 (+)-Glabrol 4:378,380 synthesis of 4:378,380 Glacialosides A,B 7:299 from Marthasterias glacialis 7:299 Glaciolide 17:14,15 Glanduliferol 6:63,64 Glaucarubin 7:394,398,660;13:660; 26:837 Glaucarubinone 7:379,383,392,394, 395,396,7:398,72,79,80,105;11:79, 80,105 Glaucarubol 7:394 Glaucasterol (papakusterol) 7:396,398; 9:37;23:299,301,304 from Pseudothesis species 9:37 from Sarcophyton glaucum 9:37 Glaucine 3:424,425;21:79 synthesis of 3:424,425 (+)-Glaucine 16:506,514 S-Glaucine 16:507 Glaucium genera 27:163 Glaucocalactone 15:141,149,158,172 Glaucocalyxin A 15:172 Glaucocalyxin B 15:172 Glaucocalyxin C 15:112 Glaucocalyxin D 15:114,121,128,172 Glaucocalyxin E 15:114,121,128,172 GLC method 25:435 (-)-Glechomafuran 20:660 Gleditsiajaponica 15:195;21:643; 24:241,243,246 saponin C from 21:643 Gleditsia macracantha 26:1140 Gleditsia saponins 15:191 Gleditsia triacanthos 26:1115,1116, 1139,1143 Gleditsiasaponin C 21:643,664 Gleicheniajaponica 25:251,276 Gleosporium fructigenum 18:715
y-Gliadin 25:320 Glial cell 27:806 Gliocadin A, C 21:235 Gliocadium virens 21:238 Gliocadium virens deliquescens 21:238 Gliocadium virens fimbriatum 21:238 Gliocladic acid 21:230 Gliocladium deliquescens 21:225 Gliocladium fimbriatum 21:182,218 viridol from 21:238 Gliocladium flavofuscum 21:238 Gliocladium fujikuroi 21:227 Gliocladium sp. 5:370;21:198,203, 215,224,227,235,237,238 gliocladins A-C from 21:235 Gliocladium vermoesenii 21:207 nectriapyron from 21:207 vermopyrone from 21:207 Gliocladium virens 21:218,229,232,239 gliodeliquescins from 21:225 viridin from 21:238 viridol from 21:238 Glioma cells 27:797 Gliotoxin 24:452,545 antiviral microbial-derived compound 24:545 FPTase inhibition by 24:452 Gliovictin 25:828 Gliovirin 21:218,219,238 Glisoflavanone 28:228 biological activity of 28:228 Globicin 7:235 Globodera 26:429,432,467,471 Globodera pallida 26:229,474 Globodera rostochiensis 26:229,430, 461,474,477,486,487 Globularidin 7:440 (-)-4-epi-Globulol 14:359 Globulol 30:724 Gloemerella cingulata 25:64,166-168 Gloeoplyllum sepiarium 23:354 Gloeosporium lacticolor 15:351 Gloeosporone 9:220,229,234,240243,245-247;10:233 synthesis of 10:233 Glomerella cingulata 5:278,415,228, 230,240;23:112,115;29:590 extracellular polysaccharide of 23:112
347
Glomerella fructigene 9:230,239 Glomerella glycines 9:230,239 Glomerella gossypii 9:230,239 Glomerella sp. 9:228,230,239 Glomerella tucumanensis 9:230,239 Glomerellan 23:115 Gloria superba 5:47 Glossina spp. 26:785 Glossodoris quadricolor 28:650 latrunculin B from 28:650 Glossostemon bruguieri 28:425 D-Glucal 2:162 Glucal triacetate 11:356,357 1,3-fl-D-Glucan 22:62 Glucan 5:276-280,287,288,291,292, 295,299,305,307,308,310-312,316, 321;23:107,115,123,126 13C-NMR assignments of 23:123 Glucanase 7:32-36,59,60;22:75 ot-Glucanase 7:60 endo-Glucanase (take-amylase) 7:34,35,42 13-1,3-Glucanasis 21:224 Glucanhydrolases 21:224 Glucan-polyolalcohol 5:318,319 [3-Glucans 23:107,111,115,135 13C-NMR spectra of 23:111 chemical structure of 23:111 functional derivative of 23:125 isolation of 23:110 occurrance of 23:108 structure-functional activity of 23:139 supramolecular structure of 23:115 c~-Glucans 23:109 Glucans 25:396 [3-D-Glucans 5:287,292,295,307,308, 310-315,316,320,321 c~-D-Glucans 5:287,307,309,310 exo-~-Glucans 7:59,60 D-[3-Glucans 107-152 of fungi 23:107-152 of yeast 23:107-152 Glucansucrase 7:69 Glucantime 26:828 Glucoamylase 29:548 affinity chromatography of
29:550 affinity purification of 29:549 electrophoresis of 29:551 gel electrophoresis of 29:549 in beverages 29:548 in confectionaries 29:548 in industrial process 29:548 in processed foods 29:548 isoelectric focusing of 29:550,551 molecular structure of 29:550 purification of 29:549 use of 29:552 Glucoamylases 2:49,50,58,62,63, 321-360;7:49,34 ;10:497,504 Glucobioses 7:69 Glucocorticoid degradation 21:657 Glucocorticoids 22:97,115;25:463,516 Glucodextranase 7:58 Glucoferulic acid 5:476 D-Glucofuranose 6:359,360,369, 370,376 Glucogitaloxin 15:362 Glucomannan 5:306 Glucono-l,4-1actone 21:239 Gluconobacter oxydans 10:530 Gluconolactone 10:386,387;30.447 Gluco-octenitol 7:60,69 23-0-,8-D-Glucophyranosyl-25methyldolichosterone 18:495 2-O-fl-D-Glucophyranosyl-3,24diepicastasterone 18:529,532 3-0-,8-D-Glucophyranosyl-3,24diepicastasterone 18:529,541 23-0-,8- D- G lucoph yranos y 1-bras s ino Iide 18:522 Gct-D-Glucopyranans 5:307,310,317 D-Glucopyranose 6:352,355,370, 373,376 Glucopyranose 7:47 ~-D-Glucopyranose 1-thiolate derivative 8:318 D-Glucopyranose 3-O-triflate 8:343,344 [3-D-Glucopyranose monoester 27:522 c~-Glucopyranoside 19:369 p-Glucopyranoside 19:369 6-O-fl-D-Glucopyranoside 25:224
348 D-Glucopyranoside 6:357-359 N-(Glucopyranoside-3-yl)-peptide ester 6:406,407 Glucopyranosides 5:657 [3-Glucopyranosyl 23:113 structure of 23:113 Glucopyranosyl 1-deoxynojirimycin derivatives 7:42 et-D-Glucopyranosyl 1-thio-c~-Dmannopyranoside 8:347 13-D-Glucopyranosyl 1-thio-[3-Dglucopyranoside ([3,13-1thiotrehalose) 8:317 4'-fl-D-Glucopyranosyl 4-hydrogen7',8'-dihydro-4,4'-diapocarotene4,4'-dioate 30:528 4-S-c~-D-Glucopyranosyl 4-thio-Dglucose 8:331,332 6-S-13-D-Glucopyranosyl 6-thio-Dglucose 8:338,339 Glucopyranosyl fluoride 7:58 D-Glucopyranosyl moiety 30:813 pharmacological activity of 30:813 ot-D-Glucopyranosyl phosphate 14:151,152 23- O-fl- D- Glucopyrano syl-2-epi- 25methyldolicho-sterone 18:495 6-S-[3-D-Glucopyranosyl-6thiocyclomalto heptaose 8:340 6-S-c~-D-G lucop yranos yl-6thiocyclomaltoheptaose 8:340 6-S-[3-D-Glucopyranosyl-6-thio-c~-Dglucopyranoside heptaacetate 8:337,338 9-D-Glucopyranosyl-adenine 4:224,225 25-fl-D-Glucopyranosyloxy-24-epibrassinolide 18:539 26-fl-D-Glucopyranosyloxy-24-epibrassinolide 18:541 (-)-( trans-4 '-f3-D-Glucop yranos ylo x y- 3 'methoxycinnamoyl) lupinine 15:521 from Lupinus luteus 15:521 (-)-( trans-4 '- [3-Glucopyranosyloxycinnamoyl)lupinine 15:521 from Lupinus luteus 15:521 5'- 13-D-Glucopyranosyloxyepij asmonic acid 6:557
[3-Glucopyranosylvalienamine 13:233 c~-D-Glucopyranosyl-ot-D-mannopyranoside 8:347,8:348 synthesis of 8:347,348 D-Glucoronic acid 23:163 13-Glucoronidase inhibitor 25:263 [3-Glucoronidases 25:313 Glucoronides 5:645 Glucosaccharo-l,4-1actone 25:263 D-Glucosamine 14:186,461 Glucosamine 30:95 Glucosaminyl-chiro-inositol phosphate 18:434 Glucose 2:321,332,262,276-278,282284 ;7:136,139,142,181 ;27:394;30:58 propranol from 27:394 D-Glucose 23:163 a-Glucose 29:555 affinity patterns for 29:555 agar diffusion of 29:555 electrophoresis of 29:556 inhibition of 29:556 Glucose ester 27:520 ofnitropropanoic acid 27:520 Glucose isomerase 2:321 Glucose oxidase 7:71,104,105,111, 112;19:701;21:239 Glucose transporter 30:817 Glucose-l-phosphate 27:821 Glucose-6-phosphate 11:216,217 a-Glucosidase 10:498,514,526,431, 247-250,86-87;19:369-370 [3-Glucosidase 2:352,379,514,526,567; 10:568,249,250;19:357,365,369; 25:210,211,308,957,968 3,8-diepialexine inhibition with 7:14 6-epi-castanospermine inhibition with 7:12 australine inhibition with 7:15 castanospermine inhibition with 7:12 DMDP inhibition with 7:15 inhibition by 2-deoxy-2-fluoro-13D-glucopyranoside 7:36 inhibition by acarbose 7:47 inhibition by conduritol B epoxide 7:38,39
349
inhibition by nojirimycin heptitol derivative 7:43 inhibition by validamycin 7:47 Glucosidase 16:108;19:356;21:590 2[3-Glucosidase 5:471 Glucosidase 1 10:526,527 Glucosidase II 10:499,526,527 a-Glucosidase I 10:501 c~-Glucosidase II 10:501 c~-Glucosidase inhibition 21:592 [3-Glucosidase inhibitor 19:369 Glucosidase inhibitors 22:30 c~-Glucosidase inhibitors 7:46,48; 13:235-246;10:496 c~-Glucosidase inhibitory activity 21:592 [3-Glucosidases 22:739;27:778 biological activity of 27:778 Glucosidases I,II 7:12,13 Glucosidation 16:296 [3-Glucoside 23:27 1 '-O-Glucoside 27:354 3-O-[3-D-Glucoside 27:517 ot-D-Glucosides 2:330 13-D-Glucosides 27:520 of nitropropanol 27:520,521 a-Glucosides 8:226,359,361,366 Glucosidic bond 16:588 Glucosinolates 25:513,514;26:1074 enzymatic breakdown of 26:1074 Glucosyl chloride 8:359-362 9-Glucosyl derivative 4:224 9-Glucosyl derivative of theophylline 4:224 1-O-Glucosyl ester 27:354 fl-Glucosyl hydrolases 25:308 Glucosyl mannoside- 1-thio-a,ecdisaccharide 8:319,8:320 24-O-[3-D-Glucosyl officigenin 7:139,140 2-O-Glucosyl samaderine-C 23:299 Glucosyl stevioside 15:19 (11R)-6-O-f3-D-Glucosyl- 11,13-dihydrotatridin B 27:572 O-Glucosylation 5:516,520,525532,545
6-C-Glucosyldiosmetin 23:747 7-O-[3-Glucosylisofraxidin 5:515 Glucosyltransferase 2:322;27:354,778 Gluco-triflate 14:155 Glucotropolin 26:481 fl-D-Glucronides 25:263 D-Gluctol 6:357,358 ~-Glucuronic acid 16:81,84 Glucuronic acid 7:156;15:26,77;22:10; 25:89,94,102-104,119,465 D-Glucuronic acid 7:294 Glucuronic acid-based inhibitor 16:115 Glucuronic prodrugs 21:169 biological behaviour of 21:169 synthesis of 21:169 [3- Glucuronidase 16:81,82,84,88,90; 21:162,690;28:283 [3-D-Glucuronidase 21:175,176 [3-Glucuronidase activity 21:177 Glucuronidation 21:138 3-Glucuronide 22:10,24 Glucuronide 22:8 Glucuronide linkage 7:156-158 Glucuronide saponins 7:156-158 Glucuronides 28:288 bioactive phenolic compounds from 28:223 in urine 28:288 glyasperin D from 28:206 glycyrrhizic acid from 28:239 glyinflanin G from 28:206 glyinflanin K from 28:206 hispaglabridin A from 28:206 3-hydroxyglabrol from 28:206 3-hydroxyparatocarpin C from 28:206 isoderone semilicoisoflavone B from 28:206 kanzonol U from 28:206 kanzonol V from 28:206 kanzonol W from 28:206 kanzonol X from 28:206 kanzonol Y from 28:206 kanzonol Z from 28:206 licorice-saponin G2 from 28:239 liquiritigenin from 28:239 medicarpin from 28:206 1-methoxyphaseollidin from
350
28:206 4'-O-methylglabridin from 28:206 shinpterocarpin from 28:206 uses as licorice 28:204 D-Glucurono-6,3-1actone 18:396,442 D-Glucuronolactone 21:170 Glucuronomannan 26:1156 Glucuronomanno-protein 23:109 D-Glucuronopyranosyl 15:7 Glucuronoxylans 2:300 Glucuroxylomannans 5:294,326,327 (R)-Glumatic acid 12:322,325 Glunapin 26:481 Gluta renghas 9:319 Glutaconaldehyde 21:386 Glutamate 21:10,14,19,101 L-Glutamate 22:668,669 [3H]-Glutamate 30:208 Glutamate N-methyl-D-aspartate receptor (NMDA) 25:519 Glutamate /NMDA receptor 21:70 Glutamate receptors 30:208 Glutamate transporters 25:536 (S)-Glutamic acid 12:322,325,19:325 Glutamic acid 2:357;11:419 L-Glutamic acid 4:148,252,438,439; 6:438,439;13:607;14:633 Glutamic pyruvic transaminase (S-GDT) 21:651;25:935 Glutamine 6:409-413;25:320 Glutamine synthetase 7:6 y-Glutamyl cysteines 23:457,460 Glutamyl peptides 6:409,410 T-Glutamyl transpeptidase 23:460,461 T-Glutamylcysteine synthetase 26:913,951 Glutarate-CoA reductase 21:212 Glutarenghol 9:319 Glutaric acid derivative 11:118 Glutaric anhydride 13:540 Glutaric dialdehyde 14:739 Glutarimide 14:740,749 Glutarimide intermediate 6:410,411 Glutarimide rings 1:313 Glutathinonylspermidine 26:808 Glutathione 22:9,10;25:219,614,831, 930
Glutathione 5-transferase (GST) activity 21:585 Glutathione peroxidase (GPx) 9:109; 23:480 Glutathione peroxidase 9:109 Glutathione peroxidase (GSHPx) 22:309 Glutathione reductase (GRd) 23:480 Glutathione reductase inhibition 26:1036 Glutathione S-transferase (GST) 9:562,576,577;21:356;23:480;25:718 Glutathionyldehydroretronecine 22:13 Glutin-5-ene 25:59 Glutinane 25:53,59;30:65 Glutinol 7:150;21:690 Glutinopallane 17:154 Glutinosin 15:167-170,172;17:199 Glyasperin A 28:226,228 anti-human immunodeficiency virus (HIV) activity of 28:226 biological activity of 28:228 Glyasperin B 28:228 biological activity of 28:228 Glyasperin C 28:228 biological activity of 28:228 Glyasperin D 28:224,228,243 anti-Helicobacter pylori activity of 28:243 anti-microbial activity of 28:62,224,257,293 biological activity of 28:228 Glyasperin J 28:228 biological activity of 28:228 Glyasperin K 28:228 biological activity of 28:228 Glycals 4:223,59-62,337-352; 10:338-341 ;30:453-458 homologation of 30:455 synthesis from 30:453-458 Glycan 6:397-404;27:506 Glycanases 8:347-351 Glycanoxylans 26:1156 Glyceollin 26:473 Glyceollin I-III 26:473 (S)-Glyceraldehyde 14:765 L-Glyceraldehyde 16:99 D,L-Glyceraldehyde 6:359
351 Glyceraldehyde-3-phosphate dehydrogenase 21:229;26:913,951 Glyceraldehyde-3-phosphate (GAP) 25:134 D-Glycero-D-galactoheptose 4:195, 198,199 L-Glycero-D-manno-heptop yranose 11:429 D-Glycero-D-manno-heptose 4:195, 202,203 Glyceroglycol lipids 25:431 (1R,2R) [1-2H1, 3H]Glycerol 11:208 Glycerol 2:20 Glycerol tri-myristate 2:48,49 Glycerol-3-phosphate dehydrogenase inhibitory activity 21:591 L-Glycero-L-manno-heptose 4:195,197202,207,209 D-Glycero-L-manno-heptose 4:197,198 D,L-Glycero-pentopyranose 6:360,361 Glyceryl [3-galactoside 7:65 Glycidol 13:70 Glycine 4:115-118;21:10,14,19,50 Glycine max 15:196;25:93,105,669; 26:930;29:578,581,593,595,604 soyasaponin A3 from 15:196 Glycine receptor 21:72;25:530 Glycine soya 25:93,101 Glycine-gated Cl-channels 25:530 Glycine-modulatory site 22:25 Glycine-rich protein 25:394 Glycinoeclepin A 22:96;26:466 D-Glycitol 6:355 Glyco analogues activity 30:817 in vivo 30:817 Glycoaldehyde 25:163,164,296,314,318 Glycoalkaloid 7:427;24:132,133; 25:296,311,317-319 from potato 25:305 molluscicidal activity of 7:427 Glycobismine A 13:371,372,374,380 Glycocitrine I,II 13:338,350,357, 358,372,373 from Glycosmis citrifolia 13:348,350 Glycocyamidine 5:549 Glycocyamine 5:549 Glycoenkephalins 30:817
Glycofoline 13:348-351 from Glycosmis citrifolia 13:348-351 Glycoforms 26:1131 Glycogen 7:32 Glycogen phosphorylase 7:29,30 Glycogen phosphorylase molecule 27:821 Glycohydrolase 7:29-37,40,47,50, 58,59,65,69 Glycohydrolase lysozyme 7:31 Glycolamide 16:84 Glycolipid biosynthesis 1:417 Glycolipids 18:785-814,143;24:799 N-Glycolylneuraminic acid 18:786 Glycolysis (GADPH inhibition) 26:924 Glycookadaic acid 5:385-386,388,389 Glycopeptide 5:279;13:202 Glycopeptide antibiotics 10:657-669 Glycopeptides aeruginosin 27:205 P-Glycoprotein 22:24 Glycoprotein 5:282-285,12,457,458, 461 ;10:143,462,479;27:736;29:547; 30:841 from earthworm 30:841 Glycoprotein biosynthesis 1:417 Glycopyranoside analogs 7:14,15 Glycopyranosyl-pyrimidines 4:224 3-O-D-Glycoronide (MGGR,7) 27:6,29 ct-Glycosidase 7:59;27:256 [3-Glycosidase 7:27,28,31 Glycosidase 7:36-48,53,55-57,60,72; 8:347,351,337-403,470,471 ;10:495573,86;16:86;19:351 Glycosidase activity 28:281 ofpolyphenols 28:281 Glycosidase inhibitors 29:467 carbaaldopyranoses synthesis of 29:467 N-Glycosidation 10:595-607 oxetanocin-A synthesis by 10:595-607 with 1-O-acyl-oxetanose 10:597-604 with oxetanosyl derivative 10:595-607 with oxetanosyl halide 10:604-607
352
Glycosidation 6:276,277;24:40,41 by mycosamine 6:276,277 by silicon ether 6:262,276,277 in (-)-pseudopterosin-A synthesis 6:74,75 Noyori's 1:671,672 of 1-O-acetyl-oxetanose 10:603 of adenine 10:605 of amphoteronolide B 6:276,277 regioselective 6:262 stereochemistry of 3:197 with oxetanosyl chloride 10:605 with silver triflate/TMU 1:670, 671 [3-directing 2-bromosugars 3:202 Glycosidation-induced shift method 26:8 a-Glycoside 21:162 Glycoside 7:133,134,136 O-Glycoside 8:315;10:344,370-380 intramolecular rearrangement 10:379 stereoselective synthesis of 10:340 Glycoside B2 (forbeside B) 7:287,288,293 from Asterias amurensis 7:287 Glycoside naringin 28:288 in urine 28:288 Glycoside structural elucidation 27:484 S-Glycosides 10:380 synthesis of 10:380 C(1)-Glycosides 10:383 Glycosides 8:359-363,337-403;17:115; 21:215,241-249,258-261,457,459; 30:203 6,8-di-C-Glycosides 5:644 ~-Glycosides 8:359,361,366 H-glycosides from 3:228 Glycosides of polyhydroxysteroids 15:60-72 1,2-cis-Glycosidic bond 14:202 1,2-trans-Glycosidic bond 14:202,204 13-Glycosidic bonds 27:314 Glycosidic linkage 16:93 Glycosidic lupine alkaloid 27:268 Glycosilation effect 27:475 Glycosmic cyanocarpa 23:343
Glycosmis bilocularis 13:348,350,355 Glycosmis citrifolia 13:348,349,361 cycloglycofoline from 13:348,349 glycocitrine I from 13:348,350 glycofoline from 13:348,349,361 pyranofoline from 13:348,350 Glycosphingolipids 10:503;26:1123 biodegradation of 10:503 biosynthesis of 10:503 from denteromycetes 18:806 from zygomycetes 18:806 isolation and purification of 18:786-797 metabolism of 10:502,503 of basidiomycetes 18:806 of fungi 18:806 of Trypanosoma cruzi 18:796802 Glycosyl amines 7:44-47 Glycosyl chlorides 8:359-361 C-Glycosyl compounds 3:213-228 Glycosyl cyanide 10:358 Glycosyl fluorides 7:58,59 Glycosyl free redicals 3:221-223 Glycosyl halides substrates 7:50-59 fl-Glycosyl hydrolase 25:304 Glycosyl hydrolases 25:306,308,321 glycosylated 25:543 Glycosyl isocyanides 3:209,210 Glycosyl manganese pentacarbonyl 10:364 Glycosyl phosphates 8:83 Glycosyl phosphatidyl inositol (GPI) 23:108 Glycosyl pyridinium salts 7:57 [3-glycosidases inhibition by 7:57 glycosidases reaction with 7:5557 Glycosyl thioformimidates 10:357 from glycosyl nitriles 10:357 Glycosyl transferases 7:69 4-O-Glycosyl-2-deoxystreptamine 14:144,145 Glycosylalkynes 10:359 Glycosylated prodrug 21:161 C-Glycosylation 1:429,430,513,514 a-Glycosylation 13:217;30:457
353
1,2-cis-Glycosylation 14:209
1,2-trans-Glycosylation 14:209
O-Glycosylation 30:814 role in 6 receptor affinity 30:814 role in ~t receptor affinity 30:814 Glycosylation 6:395,397,398,400;
10:470,471,472,474-486 cis-Glycosylation procedures 14:202
Glycosylation reactions 14:201-259 Glycosylceramidase 19:352 O-Glycosyl-C-glycosylflavone 5:644 a-Glycosyl-chiro-inositol 18:434 Glycosylcobaltoxime 10:366 6-C-Glycosylflavones 5:644 Glycosylhalides 10:355 Glycosyl-O-trichloroacetimidate 14:211 7-Glycosyl-purines 4:224 Glycosyltransferase 10:115,459,461, 495-573 Glycowithanolides 20:247 from Withania somnifera 20:247 Glycoxylon huberi 15:31 2-Glyculosonates 20:857 Glycycoumarin 28:228 biological activity of 28:228 Glycycrrhizin 25:114 Glycyphylla smilax 15:31 Glycyphyllin 15:31 ;27:17,33,34 structure of 27:34 Glycyrdione A 28:228 biological activity of 28:228 Glycyrin 28:224,228,243 anti-Helicobacter pylori activity of 28:243 anti-microbial activity of 28:224 biological activity of 28:228 Glycyrol 28:224,226,241 anti-Helicobacter pylori activity of 28:241 anti-human immunodeficiency virus (HIV) activity of 28:226 anti-microbial activity of 28:224 biological activity of 28:228 Glycyrrhetic acid 7:136,138;21:642, 645,651,655 ;22:425 ;24:215264 ;25:57,59,60,65 ;28:241
anti-Helicobacter pylori activity of 28:241 from licorice 24:216 Glycyrrhetin 24:245 G 18-fl-Glycyrrhetinic acid 25:551 18a-Glycyrrhetinic acid 25:64,551; 27:858,859 18-[~-Glycyrrhetinic acid (glycyrrhetic acid) 29:586 effects on LELA 29:586 Glycyrrhiza aspera 28:204 Glycyrrhiza eurycarpa 28:204 Glycyrrhiza glabra 15:5;21:742;22:96, 422;24:151,275,919;25:465,476;26:8 00;27:6,15,29;28:204,206,234,239; 29:589 8-(?,T-dimethyallyl)-wighteone from 28:206 3 '-(?,T-dimethylallyl)-kievitone from 28:206 edudiol (3,9-dihydroxy- 1metho xy-2-prenylpterocarpan) from 28:206 euchrenone from 28:206 flavanone from 28:239 gancaonin G from 28:206 gancaonin H from 28:206 glabrene from 28:206 glabridin from 28:206 glabrone from 28:206 glisoflavanone from 28:206 glyasperin A from 28:206 glyasperin C from 28:206 glyasperin D from 28:206 glycyrrhizic acid from 28:239 glycyrrhizin from 27:6,15,29 glyinflanin G from 28:206 glyinflanin K from 28:206 hispaglabridin A from 28:206 3-hydroxyglabrol from 28:206 3-hydroxyparatocarpin C from 28:206 isoderone semilicoisoflavone I3 from 28:206 kanzonol U from 28:206 kanzonol V from 28:206 kanzonol W from 28:206 kanzonol X from 28:206
354
kanzonol Y from 28:206 kanzonol Z from 28:206 licorice-saponin G2 from 28:239 liquiritigenin from 28:239 medicarpin from 28:206 1-methoxyphaseollidin from 28:206 4'-O-methylglabridin from 28:206 shinpterocarpin from 28:206 uses as licorice 28:204 Glycyrrhiza inflata 15:26;21:740;27:15, 29,30,425;28:204 apioglycyrrhizin from 27:15,29,30 araboglycyrrhizin from 27:15, 29,30 Glycyrrhiza korshinskyi 28:204 Glycyrrhiza pallidiflora 28:234 Glycyrrhiza species 28:223,226 anti-HIV flavonoids from 28:226 bioactive phenolic compounds from 28:223 Glycyrrhiza uralensis 21:740;28:204, 234,242;29:771 4'-O-methylglabridin from 28:242 1-methoxyphaseollidin from 28:242 3-O-methylglycyrol from 28:242 6,8-diprenylorobol from 28:242 dihydroisoflavone A from 28:242 gancaonin I from 28:242 gancaonol C from 28:242 gancaonol from 28:242 glycyrin from 28:242 hispaglabridin A from 28:242 isoglycyrol from 28:242 isolicoflavonol from 28:242 licoricone from 28:242 shinflavanone from 28:242 vestitol from 28:242 Glycyrrhizic acid 21:651 ;28:241 anti-~elicobacter pylori activity of 28:241 J Glycyrrhizin 7:142,4,22,25;21:642,655, 664,675,743 ;22:136;23:316;24:151,
880-883 ;25:90,99,103,465,467; 27:5,6,15,29;29:586 as neuromuscular blocker 24:880-883 derivatives of 24:880-883 effects on thrombin interactions 29:586 hepatoprotective effect of 25:466 structure of 27:6 Glyfoline 13:375-380 antitumor activity of 13:375-380 Glyinflanin A 28:228 biological activity of 28:228 Glyoxylate carboanion 30:452 Glyoxylic acid ester 30:466 Glyphosat 25:669 Glyptopetalum sclerocarpum 30:656, 668,670
20-hdroxy-22-oxo-20-epi-
tingenone from 30:670 20-hydroxy-22-0xotingenone from 30:670 21 c~-hydroxy-20,22-dioxo30(20--->21) abeo-21desoxotingenone from 30:670 glyptopetolide from 30:656 Glyptopetolide 30:656 13C NMR spectral data of 3i):656 ~H-NMR spectrum of 30:656 HMBC spectrum of 30:656 NOESY experiment of 30:656 stereochemistry of 30:656 structure of 30:656,657 Gm ENOD 46 25:380 Gmelanone 24:785,786 biomimetic synthesis of 24:785,786 --" Gmelina arborea 17:33~2 Gnaphalin 23:614 Gnathotricus retusus 25:143 Gnathotricus sp. 25:143 Gnathotricus sulcatus 25:143 Gnetaceae spp. 27:766 Gnetifolin 20:280 Gnetin A-C 26:535,565 Gnetin E-1 26:565 Gnetum parvifolium 26:530 Gnetum ula 9:258,263 Gnidimacrin 25:543
355
Gnoderma applantum 25:131 Gobius criniger 18:48 Gogonane skeleton 25:850 Gogonian 21:312 Goiazensolide 29:89 activity in NFkB assay system 29:89 Golden hampster 5:747 Golgi mannosidase 1A 10:559 Golgi mannosidase 1B 10:559 Golgi mannosidase II 10:559 Golgi (x-mannosidase I 10:501 Gomaline 5:154 Gomberg-Batchman-Hey reaction 20:310 Gomeraldehyde (ent-8,13,epoxylabd-15-al) 25:249 Gomeric acid 25:249,268 Gomerol 25:249 Gomisin A-C 26:197,247,256-258,263, 265 Gomisin G 26:223 Gomisin J 26:197,224,247,263 Gomisin K 26:197,247 Gomisin L 26:197,247 Gomisin M 26:197,240 as PAF-induced inhibitor 26:240 Gomisin N 26:197,247,249 Gomojosidae 25:259 Gomojosides A-J 25:251 Gomophia watsoni 15:61 Gomophioside Ai9 15:61 Gonadotrophic cycle 22:376 Gonadotropin hormone 27:795 Gonadotropin-releasing harmone 27:795,796 Gonadotropins 27:796 Goniocin 18:193 Goniodiol 19:463 8-epi-Goniodiol 19:497 Goniodomin A 19:578 antifungal activity 19:578 antifungal metabolite 19:578 (+)-Goniofufurone 19:463 Goniofufurone 9:394 Goniopypyrone 9:394,19:463 Goniothalamicin 9:395 (6R)-(+)-Goniothalamin 19:479 antifungal activity of 19:479
antitumor activity of 19:479 insect antifeedant activity of 19:479 isolation of 19:481 plant growth inhibitory effect of 19:479 (R)-(+)-Goniothalamin 19:463 Goniothalamin 9:393;19:463 Goniothalamus giganteus 9:393,395; 18:221,222 ;19:498 Goniothalamus sesquipedalis 9:393 Goniothalenol (altholactone) 9:393 (+)-Goniotriol 19:464 Goniotriol 9:393,394 Gonomia kamassi 1:124 Gonorrhea 22:607,608 Gonyaulax polyedra 25:845 Gonyaulax tamarensis 17:4 Gonyauxtoxins 21:73 Gonystylus keithii 19:764 Gorgiacerone 23:173 synthesis of 23:173 Gorgonane 18:607;25:848;23:162 (+)-[3-Gorgonene 23:162 biogenetic process towards 23:163 (-)-~3-Gorgonene 6:18,27,28 Boekman-Silver synthesis of 6:18 by Robinson annulation 6:18 from maaliol 6:28 from Pseudopterogorgia americana 6:18,27 synthesis of 6:27,28 Gorgonia flabellum 9:37 23-demethylgorgosterol from 9:37 Gorgonia ventilina 9:37 23-demthylgorgosterol from 9:37 Gorgonian octacorals 23:153-184 metabolites derived from 23:153-184 plumes of 23:153-184 pseudopterogorgia species of 23:153-184 Gorgoniidae 23:153 Gorgosterol 9:35-37,45-47;21:313; 23:169
356
Goriolus versicolor 23:132 Gorman's synthesis 14:862-864 Gorytes campestris 5:251 Gorytes mystaceu 5:251 Gossypin (gossypetin 8-O-glucoside, 3,5,7,8,3',4'-hexahydroxyflavone 8O-glucoside) 29:572 Gossypium herbaceum L. 22:521; 27:855;29:579 for epilepsy 22:522 Gossypium hirsutum 26:463;29:586 Gossypium indicum 29:572 Gossypium sp. 29:581 Gossypol 13:652,659,251;25:541,543, 544;29:586 effects on acrosin, azocoll proteinase 29:586 Gosypetone reaction 5:625 GOTO cells 21:637 Gougerotin 4:241,242 Govedine 21:57 GPI bioassay 30:807,812,814 activity of k-agonist U-50,488 in 30:807 activity of glycopeptide in 30:814 activity of Tyr-(Me)2-D-Phe-GlyVal-Val-NH2 in 30:812 activity of Tyr-(Me)2-D-Phe-NH2 in 30:812 GPP 7:110,122 G-protein 30:383 effects on inositol phosphate hydrolysis 30:383 elevation of cytosolic Ca++by 30:383 inhibition of cAMP formation by 30:383 G-protein coupled-receptor 27:825; 30:383,384 association with behavioral phenotypes 30:384 G-protein-linked receptors 21:11,14; 25:530,531,539 G-proteins 18:861 Gpysophila paniculata 24:154 GR133487 (5,5-trans-fused cyclic lactone euphane triterpene) 29:586
effects on a-chymotrypsin 29:586 effects on ot-thrombin 29:586 effects on factor XIa 29:586 effects on plasmin 29:586 effects on trypsin 29:586 Gracilaria 25:769 Gracilaria coronopifolia 25:729 Gracilaria edulis 19:570 Gracilaria verrucosa 19:571 Gracillin 23:821,824 Gracula religiosa 5:837 Gradient hetero single quantum correlation 27:470 Gradient hetero multibond correlation 27:470 Grahamamycin 4:575,576 Gralactose-rich acidic glycoprotein 25:451,452 Gram positive anaerobic bacteria 21:607 Gramicidin 10:256 Gramilaurone 13:522 Graminae 9:320,328 Gramine 21:98,109;25:531 Graminone B 26:233,235 Gram-negative bacteria 16:3;21:430, 435,599,600,607,610;30:693 Maytenus species against 30:693 Gram-positive bacteria 12:48;21:186, 235,401,403,404,405,414,599,607; 23:68;30:629,693 actamycin against 23:68 Granaticin 11:213-222 2,6-dideoxyhexose moiety of 11:214,215 Grandiflorolic acid 19:389;29:100 activity in EBV bioassay system 29:100 Grandiflorolic acid angelate 29:100 activity in EBV bioassay system 29:100 Grandisin 26:198,230,799 trypanosomicidal activity of 26:230 Grandisines I,II 13:350 Grandisinine 13:350 from Citrus grandis 13:350
357 (+)-Grandisol 1:236,643,693 synthesis of 1:643,693 Grandmal seizures 22:508 Granilin 7:212,233 Granny bush 23:657 Granulaterosides A 7:299,301 Granulatoside A 15:63 Granulocyte phagocytosis 26:47,55 ofjenisseensosides C 26:47,55 ofjenisseensosides D 26:47,55 Grape fruit oil 14:449 (+)-paradisiol from 14:449 Grape stilbenoids 23:744 Grapefriut 747 Graphium sp. 5:307,309,325 Grapholitha molesta 6:557;15:384 guidongnin from 15:142,150, 159,174 Graphosoma italicum 22:387 Grasshopper ketone 6:137,143,144,158 CD correlation with 6:137 synthesis of 6:143,144 Grateloupia filicina 25:862 Gravelliferone 4:371,372 synthesis of 4:371,372 Gravimetrical methods 21:508 Grayanotoxin 1:546,547;25:242 Grayanotoxin- 1 19:397 Graynatoxin 20:17 Greanylactone 25:166 Green fluorescent protein (GFP) 25:380 Green tea 27:417,420 biological activity of 27:417,420 Green tea polyphenols 25:470 Green's procedure 6:548 Grenadadiene 25:757,771 Grevillea banskii 9:319,320 Grevillea hilliana 9:320 Grevillea pteridifolia 9:320 Grevillea pyramidalis 9:319,354 Grevillea robusta 9:320;26:1157; 27:839 extract of 27:839 Grevillea sp. 9:329 Grevillol 9:320 Griffithine 9:149,150 Grifola frondosa 5:287;23:115,124,133 Grifola umberllata 5:287,317 Grifolan 23:115
Grifolin 9:313 Grignard addition 10:147,167,180; 16:380;19:39,45,62,541 Grignard coupling 19:45 Grignard cross coupling reaction 14:575 Grignard reaction 1:261,262,533;4:330332,353,354 ;6:159,549,550;8:165, 166;9:344,345,352,527;11:81,82, 248,249;14:670;18:473,630;20:571, 589,592,595,599,600,604 Grignard reagent 4:160;19:33,35-36,38, 513,518;20:569,585,596,598;21:384; 30:30 Grindalia haverrdii 25:252 Grindelic acid 6:107 Grindella sp. 25:251 Gringerol 24:900-902;25:757 effect of general analogues on PGF2 NA- induced contraction 24:902 Gripe-bush 23:657 Griseofulvin 4:581 ;24:934;25:757 as anti-fungal agents 24:934 synthesis of 4:581 Griseogenin 7:269 Grob-type fragmentation 24:728,731 Gromphadorhina portentosa 9:488,489 Grosshemin 1:556,559-563 Grossularine- 1 5:414-417;10:245; 23:260 Grossularine-2 5:414-417;23:260 Group transfer polymerization 8:409 Growth 30:61 of tumor cells 30:61 Growth inhibition 17:142 Growth inhibitor activity 7:407, 416-419,423 ;23:297;24:859 of cyclocolorenone 24:859 of samaderines 23:297 Grubb synthesis 6:46,47 Grubbs ruthenium catalyst 30:463 Grundmann ketone 10:54,55,68,69,71 Gryllus bimaculatus 9:492;29:6 Gryllus domesticus 22:387 GST activity 21:585 GTP-binding protein 25:385 GTP-bound stimulatory G protein 25:262 Guadalupol 6:30
358
Guaiacin A,B 5:197,200 Guaiacins A-F 9:51,58,59 Guaiacol 9:467;25:126 Guaiacum officinale 5:197,139,319, 324;9:51-59 Guaiacyl subunits 25:653 Guaiacylglycerol-~-coniferyl alcohol ether diferulate 20:634 Guaiacylglycerol-13-coniferyl ether 5:464,465 Guaiacylglycerol- ~-O-6'- (2-methoxy) cinnamyl alcohol 26:211 Guaiacylglycerol-f3-O-coniferyl alcohol 27:760 polymerization of 27:760 Guaian- 1,10-epoxide 23:813 Guaian- 12,16-olides 7:214,234-236 Guaian- 12,8-olides 7:214,236 Guaiane 7:209,214,355,607;17:154 Guaiane alcohol 14:375 ' from Nardostachysjatamansi 14:375 synthesis of 14:375 trans-Guaiane sesquiterpenes 6:546,547 Guaiane skeleton 23:161 ;25:850 Guaiane system 3:44,45 synthesis of 3:44,45 Guaiane-type diterpenes 6:11 Guaiane-type sesquiterpenes 23:814 Guaianin A 5:197,198 Guaianin A2 5:197,198 Guaianin B 5:197-199 Guaianin C 5:197,199 Guaianin E 5:199,200 Guaianins A-L 9:51,52,54-58 Guaianolide 2:280,214,215,548;6:548 from (-) a-santonin 2:280,214,215,548;6:548 6,12-Guaianolides 24:806 Guaianolides 24:80-91 Guaiazulene 5:363,369 as an anti-inflammatory agent 14:315 pigments of 25:690 Guaiazulene sesquiterpenes 1:545 Guaiazulene quinone 14:315,319,321 6-(3-Guaiazulenyl)- 1(6H)guaiazulenenone 14:320
6-(3-Guaiazulenyl)-3(6H)guaiazulenone 14:328 8-(3-Guaiazulenyl)-3,7dimethylbenzofulvene-4carbaldehyde 14:343 8-(3-Guaiazulenyl)-5-(1-hydroxy- 1methyl-ethyl)-3,7-dimethyl benzofulvene 14:343 1-(3-Guaiazulenyl)-6a-isopropyl-2,5dimethyl- 1,1 a,3,6a-tetrahydrocyclopropa [f] inden-3-one 14:320 Guaiazulenylindenones 14:315 3-(3-Guaiazulenylmethyl)-8(8aH)guaiazulenone 14:344 Guainine sesquiterpenes 23:161 Guaiol 14:313 (__)-Guaiol 14:356 Guaione 25:848 Guanidine 21:254;23:343 Guanidine alkaloids 20:488 Guanidine derivatives 21:270 Guanidinoacetic acid 5:549 Guanine-cytosine 22:27 Guanosine analong 4:237 Guanosine diphosphate 22:18 Guanosine nucleotide 22:259 Guanosine triphosphate 22:33,18; 25:598 Guanyl nucleotide exchange factor 25:548 Guar 29:545 as galacto-mannan type polysaccharide 29:545 Guayabillo 22:559 Guayacasin 23:773;26:249 Guettarda platypada 17:116,125 Guggullignan-I 5:703 Guggullignan-II 5:703 Z-Guggulsterol 5:699,700 Guggulsterol-I 5:699,700 Guggulsterol-II 5:699,700 Guggulsterol-III 5:699,700 Guggulsterol-IV 5:701 Guggulsterol-V 5:701 Guggulsterol-VI 5:699,700 Guggulsterones 5:699-701 E-Guggulsterone 5:699,700 Z-Guggulsterone 5:699,700 D-lyxo-Guggultertrol-18 5:705,706
359
D-arabino-Guggultetrol $:704,706 Guggultetrol 5:705,707 synthesis of $:705,707 Guggultetrol configurations $:704,706 Guggultetrol esters $:704-709 D-ribo-Guggultetrol-18 5:704,706,708 D-xylo-Guggultetrol- 18 5:704,706,708 Guggultetrol- 18 5:710 Guggultetrol-20 $:708 D-xylo-Guggultetrol-20-ferulate $:708 Guggulu $:695-714 constituents of $:695-714 fractionation of $:697 lignans from $:703 steroidal compounds from $:698-703 steroids of 5:709-717 Guggulu steroids $:709,712 biogenesis of 5:709,712 D-xylo-Guggulutetrol-18 ferulate $:708 Gugulipid $:715,716 Guiaflavine 26:1055,1056 Guianensine 26:1055,1056 Guianin 8:159 synthesis of 8:159 Guidimacrin 27:831 antitumor mechanism of 27:831 Guillain-Barre syndrome 22:584 Guinea-pig ileum bioassay 30:802 activity of ~t-opioid receptor in 30:802 in vitro 30:802 L-Gulonolactone 7:12 6-epi-castanospermine from 7:12 1,6-di-epi-castanospermine from 7:12 L-Gulopyranose analogs 6:373-375 Gum japonica 29:575 Gum mesquite 29:546 as acidic polysaccharide 29:546 chemical structure of 29:309,310 from mesquite tree 29:546 Gum resin $:700 Gundelia toumefortii 7:427 Gurjar's syntheses 30:33-37 of (-)-pironetin 30:33-37 or 23:535,549 Gurmarin 27:42 as sweetness inhibitor
Gutierrezia grandis 5:680;25:251 Gutierrezia microcephala 5:680,681 Gutierrezia spathulata 25:251 Gutierrezia sphacrocephala 25:251 Gutierrezia texana $:679 Gutierrezia-xanthocephahum 5:676 Guttiferae 7:409-411,417,418,420-423, 19:768;22:646,650,654,661,662 Guttiferone A 22:659 Guvacine 21:84 Gycolic acid 16:84 Gyminda 18:741 Gymnema alternifolium 27:41,43,44 alternoside I-V from 27:41 Gymnema sylvestre 15:36;18:649,650, 653,661,671,673 ;21:666,674 ;23:519; 27:40-43,48,49 gymnemasoponin III,IV,V from 27:41 gynmemic acid II-VI,VIII-XVIII from 27:41 Gymnemagenin 18:649,650;27:42,44 structure of 27:44 Gymnemanol 18:650,665 Gymnemasaponins III-V 27:41,43 as sweetness inhibitors 27:41 Gymnemasides 18:650 Gymnemic acid I-VI,VIII,XVIII 27:41, 43,44 as sweetness inhibitors 27:41 structures of 27:44 Gymnemic acid V 21:667 Gymnemic acid VII 21:666 Gymnemic acids 18:649-676 biological activity of 18:670-674 from Gymnema ~ylvestre 18:649-676 biological activity of 18:670-674 Gyrnnemoside b 21:666 Gymnestrogenin 18:649,650,656 from Gymnema sylvestre 18:649,650,656 Gymnestrogenin-type aglycone 27:47 structure of 27:47 Gymnochromes A-D 15:105-107 Gymnocladus chinensis 21:643 saponin D from 21:643 Gymnocladussaponin G 21:643,664 Gymnocolea inflata 2:280
360
Gymnocrinus richeri 15:105;28:719
gymnochrome C from 28:719 Gymnodinium 25:864 Gymnodinium breve 17:20;19:430; 21:300,301 Gymnolaemata 17:106 Gymnomitrion obtusum 13:39 Gymnomitrol 13:39-41 Gymnosperma glutinosum 5:679-681 Gymnospermae 9:317,321,323 Gymnosporia montana 23:656 Gymnotroches axillaris 7:192 Gynandropsis gynandra (L.) 28:395,405 repellent properties of 28:395 Gynandropsis pentaphylla 22:522 for convulsions 22:522 Gynostemma pentaphyllum 18:662; 21:675;24:144;27:15,28 gypenoside XX from 27:15 Gypenosides 18:650;21:675 Gypsogenic acid 24:151-153;26:29,36 mimonosides Ma from 24:151, 152 mimonosides Mb from 24:151, 152 mimonosides Mc from 24:151, 152 Gypsogenin 17:121 Gypsophila 26:55 of adjuvant activity 26:55 Gypsophila arrostii 26:38,39,40 Gypsophila bermejoi 26:44,52 Gypsophila capillaris 26:42,43 Gypsophila capitala 26:44 Gypsophilafastigiata 26:38 Gypsophila oldhamiana 26:41 Gypsophila paniculata 26:38-40,42,53 hemolytic activity of 26:41 spermicidal activity of 26:53 Gypsophila perfoliata 26:38 Gypsophila saponins 26:55 immunomodulatory effect of 55 Gypsophila sp. 24:131,144,149, ,155,161;26:55 Gypsophiloides 26:3 Gypsy moth 24:865 bioassay of 24:865 Gyrocarpine 26:824,826
Gyrocarpus americanus Jacq. 22:552 for epilepsy 22:522
Gyrophora aureolum 6:135 Gyrophora esculenta 5:311,322;23:123 Gyrostroma missouriense 15:351,383
nectriapyrone from 21:207 Gyroxanthal 6:162,163 Gyroxanthin 6:162-164
1H-NMR data 23:599-634;26:321,324, 326,329;538,539,540,541,542,543 of (+)-e-viniferin 26:540 of lO-epi-teuclatriol 23:635 of 11-hydroxy-valenc 1(10)-en-2one 23:635 of 12-epi-teucvidin 23:601 of 2-deoxychamaedroxide 23:609,610 of 3~-H-neo-clerodanes 23:607 of3-deacetylalysine B 23:634 of6-deacetylsandrasin A 23:624 of 7-epi-eudesm-4(15)-ene-1[3, 6c~-diol 23:635 of 7-epi-eudesm-4(15)-ene-1D, 613-diol 23:635 ofalysine B 23:634 ofalysine D 23:634 ofalysine E 23:634 ofampelopsin A 26:538 ofampelopsin D 26:538 ofampelopsin F 26:538 ofanigopreissin A 26:538 of balanocarpol 26:539 ofbetulifol A 26:539 ofbetulifol B 26:539 of bidentatin 23:609 of corilagin 23:426 ofcyphostemmin A 26:539 ofcyphostemmin B 26:540 of ellagitannin oligomers 23:426 of e-viniferin diol 26:540 of geraniin 23:426 of gnaphalin 23:614 ofgnetin A 26:540 of gnetin BV 26:541 of gnetin C 26:541 of gnetin F 26:541
361
of gnetin G 26:541 of hydroxyframoside A&B 26:326 ofhydroxyomoside 26:321 ofinsularoside 26:321 of isolugrandosidc acetate 26:329 of isolugrandoside 26:329 of isostrictinin 23:426 ofleachinol G 26:542 ofmalibatol A 26:542 of montanin H 23:617 of neo-clerodanes 23:601 ofnupharin A 23:426 ofparthenocissin A 26:542 ofplectrinone A 23:630 of potentillin 23:426 ofpraecoxin B 23:426 ofrestrytisol A 26:541 ofrestrytisol B 26:543 ofrestrytisol C 26:543 ofsandrasin A 23:624,625 ofsandrasin B 23:625 of strictinin 23:426 of tellimagarandin I 23:426 oftellimagarandin II 23:426 of teuchamaedrin C 23:618,619 of teucladiol 23:635 of teuclatriol 23:635 ofteucrolivin A 23:627 ofteucrolivin F 23:627 of teucvidin 23:597,599 of teucvin 23:597,599 of teuflidin 23:597,599 of teuflin 23:596,599 ofteugnaphalodin 23:619 ofteupernin A 23:607,610 of teupernin B 23:610 of teupyrin A 23:619 of teuvlncenone A 23:630 of teuvlncenone B 23:630 of teuvlncenone C 23:630 of teuvlncenone D 23:630 of teuvlncenone E 23:630 of teuvlncenone F 23:630 of teuvlncenone G 23:630 of teuvmcenone H 23:630 of teuvlncenone I 23:630 of tricuspidatol A 26:543
of vaticaffinol 23:544 of vescalagin 23:426 ofvillosin A 23:632 ofvillosin B 23:632 ofvillosin C 23:632 of viniferifuran 26:543 H +, K+-ATPase 25:613 H+/K+-ATPase inhibitor 25:612;28:676 hexaprenyl-hydroquinone sulfate as 28:676 ~H homonuclear correlation spectroscopy (COSY) 30:584 ofherveline A 30:583 IH-IH COSY 30:587 of (-)-hernone 30:587 (-)-6'-hydroxyyatein 30:587 ~H-NMR assignments 23:29 ofAc-SAMM 2 23:29 of BZSAM 23:44 ofBZSAMM 1 23:44 of ~H-NMR assignments of 23:44 of SAM 23:29 of SAM MM 1 23:29 ofSAMM 1 23:29 1H-NMR chemical shifts 23:499-507 ofbacopasaponin A 23:504 ofbacopasaponin B 506 ofbacopasaponin C 23:507 IH-NMR spectra 27:339 of abscisic acid in acetone-d6 27:339 ~H-NMR spectrum 21:733,745;27:176, 350;30:570,581-584,586,587 of (7R,8S,7'R,8'R)-(+)-7'-acetyl5 '-methoxypicropodophyllin 30:586 of (-)-6'-hydroxyyatein 30:587 of (-)-hernone 30:587 of (+)-malekulatine 30:584 of (+)-N-formylovigerine 30:582 of 7-formyldehydroovigerine 30:581 of chelerythrine free base 27:176 of demethylsonodione 30:570 of ernamymphine 30:582 ofherveline A 30:583 ofphaseic acid 27:350
362
tH-NMR studies 27:338 of abscisic acid 27:338 HIV inhibitors 25:942 H2 receptors 25:612 H202-induced apoptosis 25:269 HA 26:1002-1004 antibacterial activity of 26:1002 as a carcinogen 26:1002-1004 HA inhibitors 27:116-129 2 ~-chlori-peracetyl-Neu methyl ester 27:124,127 4-(8-morpholin) capriloylNeu5Ac-~x2Me 27:126,127 4,7-di-O-acetyl-Neu5 Ac-cz2Me 27:123 4-capriloyl-Neu5 Ac-cz2Me 27:125-127 4-O-acetyl-Neu5 Ac-cz2Me 27:123 4-O-capriloyl-Neu5 Ac-2Me 27:125 4-O-phenyl-2-propionylNeu5Ac-cz2Me 27:123 4-t-butyl-dimethyl-silyl ether 27:127 5-azido-5-deamino-Neu5Accz2Me 27:119 5-N-benzyloxycarbonyl-Neuot2Me 27:119 5-N-propionyl-Neu-cz2Me 27:119 7-deoxy-Neu5 Ac-(x2Me 27:123,127 8-amino-8-deoxy-Neu5Ac 27:121,122 8-azido-8-deoxy-Neu5Ac 27:121,122 8-tosyl-Neu5AcMe ester 27:121,122 9-amino-9-deoxy-Neu5 Ac 27:121,122 9-amino-9-deoxy-Neu5Ac-cz2Me 27:119 9-azido-9-deoxy-Neu5 Ac 27:121,22 9-azido-9-deoxy-Neu5 Ac-cx2Me 27:119 9-O-acetyl-Neu5 Ac-ot2Me
27:119 9-tosyl-Neu5AcMe ester 27:121,122 Neu 5Ac methyl ester 27:120-122 Neu5Ac-cz2Me 27:119-121 Neu5Ac-(x2Me amide 27:119, 120 Neu5Ac-cz2Me benzyl ester 27:125-127 Neu5Ac-o~2Me methyl ester 27:125-127 Neu5Ac-[32Me methyl ester 313 27:125,127 peracetyl-Neu-cz2Me acid methyl ester 27:124,127 Haageanolide 8:195-201 Haber-Weiss reaction 22:327,435; 26:975 Hacelia attenuata 7:290,295,304-306; 15:61 (+)-Haedoxan A 26:231,232 (+)-Haedoxan B 26:231,232 (-)-Haedoxan D 26:231 (+)-Haedoxan D 26:231 Haemagglutinin (HA) 16:93,102; 27:103,107 for influenza infection 27:103 inhibitors of 27:117-129 Haemagglutinin-based inhibitors 16:111 Haemanthamine 20:325,353,356,369, 383 Haemanthidine 20:352 Haemaphysalis intermedia 28:400 Haematococcus pluvialis 21:305 Haematoxylin 15:34,20:781,782-784 Haematoxylon campechainum 15:34, 20:776;27:18 hematoxylin from 27:18 Haemodoraceae 17:372 Haemolymph 22:374,382,391 Haemolytic activity 23:512 of saikosaponins 23:512 Haemonchus 26:425 Haemonchus contortus 22:401 ;25:794; 26:429,431,432,440,446,451,453,45 7,470,482,484,488,490,491 ;28:342, 349
363
Haemophilus influenzae 4:195 ;25:781 Haemopoietic stem cells 30:766 Haemorrhagic fever virus (CCHFV) 30:410 Hairy root cultures 17:426 Hakamori method 2:336;15:192 Hakamori permethylation 5:199 Hakea 26:1157 Hakea amplexicaulis 9:320 tlakea gibbosa 29:576 Hakea persihana 9:320 Hakea trifurcata 9:320 Hakomori's procedure 27:512 Halcyon smyrnensis 5:837 Halenaquinol 6:4;25:694 Halenaquinol dimethyl ether 17:40 Halenaquinol sulfate 28:677 absolute stereochemistry of 28:677 as pentacyclic hydroquinone 28:677 as yellow pigment 28:677 Halenaquinone 17:33;25:861 (+)-Halenequinol 17:48-50,55-61 (+)-Halenequinone 17:48-50,55-61 Haliangolides 7:210,211 Haliangolidin 7:230 Halicerebroside A 18:459 Halichlorine 25:799 Halichondria 27:875;28:658 Halichondria cf. moorei 28:698 Halichondria cylindrata 23:341 ;28:139, 680 Halichondriajaponica 18:475;25:718 Halichondria melanodocia 5:387 Halichondria okadai 5:378,379,383, 384;21:411;25:799 Halichondria panicea 17:719;25:852; 28:661 Halichondria sp. 17:17;21:329,330; 25:716,847,848,852,854 ;28:659,660 diterpenoid from 28:659 from Marshall islands 28:660 guai-6-ene skeleton of 28:660 sesqui- and diterpenoids from 28:659 Halichondria sponge 21:252;28:663 isothiocyanates from 28:663 Halichondrida order 28:658
Halichondride antitumor activity of 5:378,380 Halichondriidae 28:671 Halichondrin 25:728 Halichondrin I3 25:727 Halichondrins B,C 5:377-382 Haliclona exigua 21:267 Haliclona nigra 28:684 from Papua New Guinea 28:684 haligramides A of 28:684 Haliclona rubens 21:308 Haliclona sp. 5:346,347,459,706; 21:260,674 ;25:694,695,709,710,725, 728;28:706 haliclostanone sulfate from 28:706 Haliclonacyclamines 25:710 Haliclonadiamine 24:573,650,659 Halicona kormella 25:722 Halicona oxigua 25:732 Halicyclamine A 21:308 Halicylindramide A 23:341;25:867; 28:680 as antifungal substance 28:680 as cytotoxic substance 28:680 Halicylindramide B 23:341 ;25:867; 28:680 as antifungal substance 28:680 as cytotoxic substance 28:680 Halicylindramide C 23:341 ;25:865,867; 28:680 as antifungal substance 28:680 as cytotoxic substance 28:680 Halicylindramides E 25:866,867 Halimeda incrassata 18:689 Halimeda tuna 689 Haliotis discus hannai 25:788 (-)-Halipanicine 25:852 Halipanicine 28:661 total synthesis of 28:661 Halistanol disulfate B 25:704;28:699 in endothelin converting enzyme (ECE) assay 28:699 Halistanol sulfate 28:698 antimicrobial activity of 28:698 hemolytic activity of 28:698 ichthyotoxic activity of 28:698 pp60v-src protein tyrosine kinase inhibition activity 28:698
364 Halistanol trisulphate 25:704;27:861 Halisulphate 25:263,799 derivative 25:699 Halitunal 16:302 antiviral activity of 16:302 Halityle regularis 7:297;15:61 halityloside D and I from 15:61 gomophioside A from 15:61 halitylosides A,B,D,E,F,H,I from 7:297 Halityloside A, I 15:61 from Halityle regularis 15:61 Halitylosides A,B,D,E,F,H,I 7:298 from Halityle regularis 7:297 from Nordoa gomophia 7:298 from Nordona novaecaledonia 7:298 from Sphaerodiscus placenta 7:298 Hallerone 16:616 Hallucinogenic agent 21:101 w-Halo-acids 8:239 (c~-Haloalkyl) (alkyl) boronic ester 11:409 (c~-Haloalkyl) boronic ester 11:409,410 amino acids from 11:417-420 carbohydrates from 11:420-422 from alkenyl boronic esters 11:409,410 synthesis of 11:409,410 Haloamidation 14:568 Halobacterium sp. 7:355 bacterioruberin from 7:355 Halocyamine A 23:243 Halocyamine B 23:243 Halocynthia papillosa 28:642 6-methylheptyl sulfate from 28:642 (E)-oct-5-enyl sulfate from 28:642 Halocynthia roretzi 6:152;23:243; 25:704,784 ;28:642 halocynthiaxanthin from 6:152 mytiloxanthinone from 6:152 Halocynthiaxanthin 6:142,143,152 from Halocynthia roretzi 6:152 et-Haloester 11:117 dioxoester from 11:117
Halofantrine 20:516;22:148 Halogenated analogues 12:398 Halogenated cyclic peptides 23:341 Halogenated quinones 4:331,332 coupling of 4:331,332 Halogenation 27:749,752 of olefins 27:749,752 Halogen-containing antibiotics 29:309 biological effects of 29:309 chemical structure of 29:309,310 chloramphenicol as 29:309 chlorinated derivatives as 29:309 fluoroacetate as 29:310 4-fluorothreonine as 29:310 from Streptomyces venezuelae 29:309 from streptomycetes 29:309 in aquatic organisms 29:309 in terrestrial organisms 29:309 isolation of 29:309 occurrence of 29:309 Halogene-nucleophile 19:438 Halogen-free malyngamide J 25:788 (E)-13-Halogenoacrylamides 21:381 1-Halogenobenzyl isoquinoline derivatives 6:482 dibenz [d,f] azonine derivatives from 6:482 Halohydrin formation 11:141 2-deoxy-l-hydroxy sugars from 11:141 Halolactonizations 1:627-629 of cycloalkene ketals 1:627-629 a-Halomethylcycloheptanone 8:35,36 synthesis of 8:35,36 c~-Halomethyltetrahydroeucarvones 8:36 Halomicin 23:54 Halomon 25:702 Halopappus parvifolus 25:255 Halopappus sp. 25:251 Haloperoxidase 25:758 Halophilic bacteria 30:520 Halophylidin 22:522,539 Halopuupehenones 6:26:233 from Heteronema 6:26:233 synthesis of 6:23,24
365
Halotyrosine-derived metabolites 21:307 Halymenia porphyroides 9:85,86,88 marine N-acylsphingosine from 9:85,86,88 Halyminine 9:85,86,88 Hamamelis virginiana 21:543;29:588 (+)-Hamatine 20:422-424 Hamigera tarangaensis 25:803 Hamigeran B 25:803 Haminaea templadoi 26:90 Hamioea cymbalum 25:787 Hamster assay 21:671 Hamster fetus 23:570 encephalocele in 23:570 Hamycin 26:794,795 Hanacantha sp. 25:705 Hanalpinol 23:813,814 Hanalpinone 814 Hanamyol 23:813 Hanessian reaction 1:511,512 Hanessian's deconj ugation-epimerization 12:13 of avermectin Bla derivatives 12:13 Hanessian's epimerization 12:28 macrocyclization with 12:28 Hanessian's procedure 12:347 from debenzylidenation 12:347 Hanessian's synthesis 12:12-15 ofavermeetin Bla 12:12-15 Hanfillin 27:564 Hanging drop vapor-diffusion technique 30:831 of EFEa 30:831 Hannoa klaineana 18:726;23:302 Hannoa quassiaundulata 26:466 Hannokinin 17:360 Hannokinol 17:360 Hanphyllin 7:230 Hanseniaspora osmophila 5:283 Hansenula beijerinkii 5:287 Hansenula bimundalis var. americana 5:287 Hansenula capsulata 5:280,284,315 Hansenula ciferii 5:287 Hansenula fabianii 5:287 Hansenula minuta 5:315 Hansenula mrakii 5:287;25:129
Hansenula polymorpha 22:601; 26:1263,1267,1270,1272,1274
Hansenula saturnus 5:287 Hansenula sp. 5:281,282,315 ;26:1087 mannans from 5:282
Hansenula subpelliculosa 5:282 Hansenula wingei 5:282 Hansfordia pulvinata 6:413-415 IH, laC-NMR of analogs 6:413-415 of MurNAc 6:413-415 Hantzsch synthesis 4:86 racemization during 4:86 Hapalindole A 21:362;26:363 (+)-Hapalindole Q 16:131 Hapalindoles 11:278 from Hapalosiphon fontinalis 11:278 Hapalochlaena maculosa 18:724 Hapalopilus nidulans 29:265 Hapalopilus rutilans 29:265 Hapalosin 25:714 Hapalosiphon fontinalis 11:278;21:362; 26:363 hapalindoles from 11:278 Hapalosiphon intricatus 26:363 Hapatocyte necrosis 25:462 Hapatotoxins 25:461 Haplopappus 29:577 Haplopappus canescens 29:577,580, 581 Haplophyllum dauricum 17:335 Haplophyllum dubium 22:522 Haplophyllum glabruinum 22:522 Haplophyllum hispanicum 26:263 diphyllin acetyl apioside from 26:263 tuberculatin from 26:263 Haplophyllum perforatum 22:522 Haplosamate A 25:898;28:703 as HIV- 1 integrase inhibitor 28:703 Haplosamate B 25:898 Happlopappus arbutoides 25:251 Happlopappus pulchellus 25:251 Hapten-carrier protein conjugated 25:434 Harappamine 2:176,177 Hard acids/bases 3:409
366
Hardwickiic acid 30:710,711 structure of 30:710,711 Harmaline 5:190;21:68,89,96,97,102, 108,109;22:24,36;25:533,537; 26:828,829 as immunosuppressive drug 25:537 tautomerism of 5:190 Harman 5:353;18:726;26:828,829 from Costaticella hastata 18:726 Harmine 21:68,80,96,97,102,108;22:28; 25:533,537 as immunosuppressive drug 25:537 Harpagide 7:455,459,460-466,477; 29:83 activity in EBV assay system 29:83 Harringtonine 21:97 Harzianic acid 21:216;28:135 antibiotic activity of 28:136 Harzianopyridone 21:213,214 Haslinger and Michel synthesis 14:689-692 of taxodione 14:689-692 Hasnenula holstii 5:280,285,315 Hastanecine 1:245,246,252,253 synthesis of 1:245,246,252,253 (+)-Hastanecine 12:472 Hastatoside 7:455 Hatanecine 3:54 Hatch-Slack metabolism 13:330 Haticondria cylindrata 25:867 Hatistanol sulfates 25:703 Hattalin 26:216,269 ouabain receptor 26:216 Hazimycin 21:362 Hazuntine 9:193 Hazuntinine 5:124 Hazuntiphylline 5:129 HBsAg 21:648;20:533 HBsAg secretion 20:539 HBV 30:406 immunization against 30:406 HBV infection 20:528-530 HBV infectivity 30:406 HCMV 21:665,666 HCT 15(cdon) 22:621
H-Dmt-Tic-Ala-OH (DTA) 30:804 as 5-opioid receptor antagonist 30:804 H-D-Phe-c-(Cys-Tyr-D-Trp-Arg-ThrPen)Thr-NH2 30:813 from somatostatin 30:813 Headache 30:192 use of non-steroidal antiinflammatory drugs (N SAIDs) 30:192 use of prostaglandin inhibitors 30:192 Head-to-tail polymerization 27:774 Healing properties 22:361 of 3',4-O-dimethylcedrusin 22:361 Heamanthidine 4:3,4 from amaryllidaceae 4:3,4 pretazettine from 4:17 synthesis of 4:17-20 Heart diseases 30:55 role of natural products in 30:55 Heart rate 26:183 effect of Schisandra on 26:183 Heartworm 1:435 Heat-activated channel TRPVI 30:193 type of ionotropic receptor 30:193 Heathcock's asymmetric aldol reaction 18:283 Heat-inactivated proteases 25:439 Hebesterol 9:43 biosynthesis of 9:43 from Petrosia hebes 9:37 Heck arylation 19:274,19:277 Heck coupling 19:276 Heck reaction 16:367,391,400,412,416, 418,427,429,430,432,435,438,439, 447;18:96;19:22,78,279,284 asymmetric 19:22 intramolecular 16:429,430,438, 439 of olefin 19:279 palladium-catalyzed 19:78 Pd(0) catalyzed 16:439 silver modifaction of 16:429 with 1-octen-3-one 16:391 Heck reaction conditions 19:227,279
367 Heck vinylation 16:432 intramolecular 16:432 Hecubine 5:172 Hedamycin 11:136 Hedeoma pulegioides L. 22:522 for convulsions and spasms 22:522 Hedera helix 7:427,20:6;21:642,662, 674 ;24:132,133 ;26:813 ;29:586 Hederagenin 7:134,135,429,431-433, 9:61,62;21:656,665 ;22:97;25:60 molluscicidal activity of 7:432 Hederagenin (triterpene) 29:586 effects on LELA 29:586 Hederagenin monodesmosides 30.'203, 204 agglutination inhibition by 30:204 anti-rheumatoidal effect of 30:204 edema inhibition by 30:204 effect on trypsin activity 30:204 kalopanaxsaponins-A 30:203 kalopanaxsaponins-I 30:203 trypsin production inhibition by 30:204 use in chronic rheumatoidal arthritis 30:204 vascular permeability inhibition by 30:204 Hederagin 26:814 c~-Hederin 21:642,656;20:6;26:814 [3-Hederin 20:6;26:814 Hedychenone 23:838 Hedychium 23:837 Hedychium coronarium 23:836;24:284; 25:265 Hedychium flavum 27:377 Heimerlein 27:564 Heinsia crinata 151 Heinsiagenin A,B 10:151 Heisteria pallida 22:360 HeLa 25:301 cells 25:268 HeLa 229 cells 21:718 HeLa assay 25:45 HeLa cells inhibition 25:45,46 HeLa $3 cells 21:263;25:790 Heldrichinic acid 20:670 from Salvia napifolia 20:670
Helenalin 20:10;29:90 activity in CRG assay system 29:90 activity in NFkB assay system 29:90 Helenalin acetate 29:90 activity in NFAT assay system 29:90 activity in NFkB assay system 29:90 Helenalin isobutyrate 29:90 activity in NFAT assay system 29:90 activity in NFkB assay system 29:90 Helenalin tigulinate 29:90 activity in NFAT assay system 29:90 activity in NFkB assay system 29:90 Helenanes 16:664 antiinflammatory activity of 16:664 antileukemic activity of 16:664 cyctotoxic activity of 16:664 Helenanolide 16:133 synthesis of 16:133 Helenanolide intermediate 4:674 Helenium 26:436 Helenium amarum 20:10 Helenium microce 20:10 Heliangolides 24:806 Helianthus 29:589 Helianthus annuus 19:247;21:634,660; 25:391,670;29:593,600 Heliantriol C 25:57,62 Heliantriol C (taraxast-20-ene-3~,1613, 22c~-triol) 29:587 effects on CHY 29:587 Heliantriol C 3-O-myristate (taraxast20-ene-3[~,16~,22~-triol 3-0myristate) 29:587 effects on TRY 29:587 Heliantroil Bo 22:122 Heliantroil B2 22:122 Heliantroil C 22:122 Heliantrol B2 25:57 Helicacus kanaloanus 15:383
368
Helichrysum gymnocephalum 27:377 Helichrysum nitens 5:413 antifungal flavonoids from 5:651
Helichrysum picardii 29:702 Helichrysum rupestre 25:259 Helichrysum setosum 22:522
for epilepsy 22:522 Helicity rules 2:164,165 Helicobacter pylori 13:183;22:432; 25:611,617,618,778;26:693;30:338 Helicobacter pylori inhibition 30:338 by chrysophanol 30:338 by emodin 30:338 by rhein 30:338 Helicondria sp. 9:37 petrosterol from 9:37 Heliconius pachinus 8:222 macrolide from 8:222 Helicostylium piriforme 25:317 Helicoverpa zea 26:697;29:292 Helicteres isora 26:226 helisorin from 26:226 helisterculin A&B from 26:226 Heliettin 22:517,538 Heliocidaris erythrogramma 17:95 Heliocide B 4:618,619 biosynthesis of 4:618,619 Helioporuns A-E 25:690 Heliopsis buphthalmoides 17:319 Heliopsis helianthoide 5:334,728 hemoglobin components of 5:836-839 in bird species 5:836-839 Heliopsis longipes 7:427;24:689 Heliothis armigera 23:66;26:850,851 Heliothis virescens 7:395;21:252; 25:768;26:439,485 Heliotridane 1:54,239,243,256,258 synthesis of 1:54,239,243,256, 258 (+)-Heliotridane 16:444 synthesis of 16:444 Heliotridine 1:231,232,246 synthesis of 1:231,232,246 (+)-Heliotridine 12:472-474 synthesis of 12:472-474 Heliotrine 1:267,268 synthesis of 1:267,268 Heliotropium bovei 26:874
Heliotropium floridum 26:874 Heliotropium megalantum 26:874 Heliotropium sinuatum 26:874 Heliotropium sp. 26:872 Heliotropium strygosum 19:145 Helioxanthin 17:334;26:194,232 synthesis of 17:334 Helisorin 26:226 Helisterculin A&B 26:226 Helix promatia 18:655;19:636;25:210; 27:468 Helleborus purpurescens 21:657 Helmchen's camphor 8:416 Helmindiol 26:451 (+)-Helminthosporal 16:265 synthesis of 16:265 Helminthosporal 8:162,163 Helminthosporin teres 2:434 Helrninthosporium 25:828 Helminthosporium carbonum 22:459; 27:498,499 Helminthosporium gramieu 26:1210 Helminthosporium oryzae 9:237 Helminthosporium sativum 4:23,24,192 Helminthosporium sigmoideum 22:273 Helvella gyomitra 9:203 Hemacytometer 9:232 Hemagglutinins 24:478-483,484 assay 24:483-480 Hemandezine 21:79 Hemangiomas 26:693 Hemanthamine 21:97 [3-Hematin 25:343 fl-Hematin aggregation 25:342,354 inhibition of 25:342,354 Hematologic toxicity 27:436;28:559 with immunosuppression 28:559 with leukopenia 28:559 Hematopoietic cancer cells apoptosis 26:925 Hematoporetic stem cell 27:806 Hematoporphyrin 25:354 Hematoporphyrin IX 25:355 (+)-Hematoxylin 27:18,37,38 structure of 27:38 Heme aggregation 25:329,343,349,351, 352,353,355,356 Heme aggregation activity 25:341
369
Heme aggregation assays 25:348,352, 354 Heme aggregation efficacy 25:355 Heme aggregation inhibitor 25:327,329, 343,352,359 Heme detoxification 25:329,331 Heme polymerase 25:30,333 Heme polymerization 25:334,348 inhibition of 25:348 Heme polymerization assay 25:334,354 Heme polymerization inhibitor 25:327, 343,347,348 Heme polymerization inhibitory activity 25:345 Heme proteolysis 25:331 Heme sequestration 25:348 inhibition of 25:384 13-Hemetin 25:31,38,332,333,340,356, 357,358,360 inhibitor of 25:357 [3-Hemetin aggregation 25:357 [3-Hemetin assay 25:355 11,15-Hemiacetal 25:266 Hemiacetal 7:465 Hemiacetal ethers 27:189 retrosynthetic analysis of 27:189 Hemiacetal isomers 21:143 Hemiacetal moiety 30:450 reduction of 30:450 ozonolysis process 30:450 Hemiacetalization reaction 30:437 Hemibiotrophic tomato pathogen 25:302,308 Hemicellulose 7:195 Hemicentrotus pulcherrimus 26:1188; 28:717;29:268 Hemicryptophyte plant 27:663 Hemidesmus indicus R. 22:522 for epilepsy and nocturnal epilepsy 22:522 Hemimetabolous 22:376 Hemin 25:337 Heminitidulan 4:391,392 synthesis of 4:391,392 Hemiptera 22:398 Hemisphere rule 2:165 Hemi-synthesis 18:219,220 of acetogenins 18:219-222 of solamin 18:219,220
of reticulatacin 18:219,220 of corrossolone 18:220,221 of isodeacetyl uvariein 18:221 of gigantccin 18:221,222 Hemodynamic changes 23:12 Hemoglobin 30:59,60,65-67,69 carp oil effects on 30:66 effect of oleic acid on 30:65 effects of triterpenoid fractions on 59 oleic acid effects on 30:67 Hemoglobin proteolytic enzyme 25:360 Hemoglobin/HA interactions 26:985-987 Hemoglobinase 25:330 Hemolysins 9:317 Hemolysis 25:180,464 Hemolytic activity 21:660,661;26:41, 42;28:698 of Gypsophila paniculata 26:41 ofhalistanol sulfate 28:698 of SAPO 30 26:41 of SAPO 50 26:4I Hemophilus influenzae 13:162,177,181 Hemorrhage complication 30:839 Hemorrhage-inducing activity 23:139 Hemosiderin 22:327 Hemostatic process 30:593 role of platelets in 30:593 Hemozoin 25:354 inhibition of 25:354 Hemozoin aggregation 25:334,337 Hemozoin aggregation inhibition 25:342 Hemozoin inhibition 25:341,342,356 Hemozoin inhibitor drugs 25:360 Hemozoin nucleation 25:334 Hemozoins composition 25:338 Hemsleya carnosiflora 24:249;27:14; 29:53 carnosifloside V from 27:14 carnosifloside VI from 27:14 Hemsleya panacisscandens 24:249; 27:15,25 scandenoside R6 from 27:15,25 scandenoside R11 from 27:15,25 (Z)-Heneicos-6-en-11-one 19:124,126 sex pheromone of 19:124,126 (Z)-4-Heneicosenal 26:81
370
Henricia laeviuscola 15:48,55;28:718 henricioside from 15:48,55 Henricioside A 15:48 from Henricia laeviuscola 15:48 Henry condensation 1:408,409 Henry reaction 19:120,165,173 pyperidine-catalyzed 19:165 Henrycine A 15:115,122,129,171,172 13C-NMR of 15:129 from Rabdosia flexicaulis 15:171 from Rabdosia henryi 15:172 ~H-NMR of 15:122 Henryin (reniformin A) 15:172 J3C-NMR of 15:131 from Rabdosia henryi 15:172 from Rabdosia latifolia var. reniformis 15:172 lH-NMR of 15:124 Hep-2 (human carcinoma of larynx) 30:692 Heparanase activity 16:90 in malignant cells 16:90 Heparin 30:58,397,404 against pseudorabies virus 30:404 in HIV therapy 30:397 Heparin derivatives 30:399 anticoagulant activity of 30:399 Hepatic activity 26:253 Hepatic apoptosis 25:468 Hepatic DNA fragmentation 25:466, 467,468,469,472 Hepatic information 25:479 Hepatic intoxication 25:466 with D-Gal N 25:466 with LPS 25:466 Hepatic mRNA induction 25:468 Hepatic total cholesterol concentration 30:93 effects of Platycodi radix on 30:93 Hepatic triacylglycerol 30:81,93 accumulation of 30:93 effect of high-fat diet on 30:93 Hepatic triyglyceride 30:81 Hepaticae 2:277;9:249 Hepatitis 26:183;30:207 effect of Schisandra in 26:183
treatment of 30:207 use of Phyllanthus (genus) in 207 Hepatitis A virus 30:406 Hepatitis A 21:662 Hepatitis B 21:662 Hepatitis C 21:662 Hepatitis B capsid 30:406 Hepatitis B surface antigen 20:537 Hepatitis B virus 20:227,528;21:648, 656;25:114 Hepatitis D agent 30:406 Hepatitis-B surface antigen 30:840 bromelain 30:840 Hepatocarcinogenesis 26:257 Hepatocellular uridine phosphate UDP and UTP 25:461 Hepatocyte apoptosis 25:459,460,462, 464,468,469 Hepatocyte necrosis 25:466,468,476 Hepatocytes 23:14 Hepatoma cell 27:806 Hepatoma cell line PLC/PRF/5 30:406 Hepatopretective agent 22:358 ursolic acid as 22:358 Hepatoprotective agent 22:346,358; 23:753;25:462,465 Achyrocline satureioides as 22:346 ursolic acid as 22:358 Hepatoprotective activity 20:116; 25:90,103,106,467,469,474 ;26:255, 257 ;28:257,293 ;30:291 ofbaicalein 30:291 ofbaicalin 30:291 of bupleuroside III,IV,XIII 25:474 of Curcumia longa L. 25:469 of ornithine glucuronides 25:90,103 of palustroside III 25:106 of plant polyphenols 28:257,293 of tetrahydroswertianolin (THS) 25:467 of wogonin 30:291 Hepatoprotective drugs 25:100,103 Hepatoprotective effect 25:100,106, 466,472 assay method for 25:100 of Colchicum autumnale 25:472
371 of glycyrrhizin 25:466 of oleanolic acid-type glucuronide saponins 25:106 of plants 25:459 of sinomenine 25:472,476 Hepatoprotective mechanism 25:472 of coumarins 25:472 Hepatoprotective natural products 25:465 Hepatoprotective phytoconstituents 25:477 Hepatoprotective proteins 25:461 Hepatoprotective saponin 25:465 Hepatosplenomegaly 26:785 Hepatotoxcity 21:651,654 Hepatotoxic cyclic peptides 20:887-913 of cyanobacterial origin 20:887-913 Hepatotoxic principle 27:879 of Anabaena genera 27:879 of Microcystis genera 27:879 of Oscillatoria genera 27:879 Hepatotoxicity 22:8;25:461,471 cyanobacterial 9:496-499 Hepelidic acid 21:230 Hepoxilin 9:576 Hepoxilins (hydro-epoxides) 9:577 Heptaacetyl tunicaminyl uracil 1:420, 421,572 5,9-Heptacosadienoic 25:721 Heptacyclic tropone 11:125 (8 E)-Heptadeca- 1,8,dien-4,6-diyn-3,10diol 27:422 structure of 27:422 1,Z-8-Heptadecadiene 2:8 9-Heptadecenoic acid 21:189 2,3,4,5,2',3'.4'-Heptahydroxybenzophenone 25:351 Heptaketide 21:209,311 Heptamethoxyflavone 23:747;26:752 Heptanal 9:338,339 Heptanedioic acid derivative 11:117 tetraoxoalkanedioates 11:117 Heptanoic acid 26:361 Heptanolide 10:232 from Baeyer-Villiger reaction 10:232 Heptanone 30:41 oxidation of 30:41
Heptapeptide lissodinamide 25:878 Heptapeptides 25:715,883 Heptaphylline 2:118,2:119 (+)-Heptelidic acid 21:229-231 Heptenes 9:400 Heptitol 4:17;11:429 Heptobioses 4:205,206 Heptodialdopyranose derivative 4:180, 181 Wittig olefination of 4:180,181 Heptose region of oligosacchardies 4:195-216 synthesis of 4:195-216 Heptuloses 11:429 Heptulosonic 30:473 synthesis of 30:473 Heptulosonic acid analogues 30:473 Mukaiyama reaction of 30:473 15[3-Heptylachaparrinone 26:815 Heracleum L. 21:615 Heracleum sibiricum 22:522 Heracleum verticillatum 22:522 (+)-Herandulcin 16:229 synthesis of 16:229 Herbacetin-3,8-dimethyl ether 5:624 Herbacetin-8-methyl ether 3-diglucoside 5:623 Herbadysidolide 21:310 Herbal antidepressant 30:333 Hypericum perforatum as 30:333 Herbal drugs 25:44 as antitumor-promotor 25:44 Herbal formulation AV/EPP/14 28:401 against larvae 28:402 against nymphs of Boophilus microplus 28:402 Herbal medicines 24:261 activities of 24:261 HerbamideA 25:900 Herbasolide 25:692 Herbasterol 5:410 antimicrobial activity of 5:410 cytotoxic activity of 5:410 Herbicidal 24:799,867 bioassay of 24:867 biological activity 24:799 Herbicidal activity 21:435;23:73;24:819 against dicotyledonous plants 23:73
372 against monocotyledonous plants 23:73 of Piqueria trinervia 24:779, 817-819 Herbicidal antibiotic 5:592,607 Herbicides 7:398,383,384,387;25:668 Herbimycin 5:592;21:420,435;23:54 as an antitumor antibiotic 5:592 as herbicidal agent 5:592 Herbimycin A 21:442 Herbivorous crustacean zooplankton 26:355 Herbolide A-F,H,I 7:230,233 Hercynolactone 5:729,730 Herdmania curvata 21:366 Heritianin 7:185-187 Heritiera littoralis 7:176,177,180,181, 185,187,190 Heritol 7:185,187 Heritonin 7:185,187 Hernamymphine 30:582 HREIMS of 30:582 ~H-NMR spectrum of 30:582 IR spectrum of 30:582 molecular formula of 30:582 UV absorptions of 30:582 (+)-Hernandaline 30:563,594 as platelet aggregation inhibitor 30:594 Hemandezine 22:35 Hernandia 30:559-561,563-580 benzenoids from 30:562 bioactive constituents of 30:559 biological studies of 30:561 classification of 30:560 division of 30:560 economic applications of 30:559 ethnobotanical studies of 30:561 family of 30:560 flavonoids from 30:562 genus of 30:560 hemandiaceae family of 30:559 isoindole from 30:562 isoquinoline alkaloids from 30:560,562 lignans from 30:560,562 monoterpenoids from 30:562 pyridine from 30:562 species of 30:559
sterols from 30:562 subclass of 30:560 subfamily of 30:560 Hernandia albiflora 30:560 (-)-laetine from 30:564 (+)-actinodaphnine from 30:563 (+)-corytuberine from 30:563 (+)-hemagine from 30:563 (+)-hernandaline from 30:563 (+)-hernovine from 30:564 (+)-isoboldine from 30:564 (+)-isocorydine from 30:564 (+)-laurotetanine from 30:564 (+)-magnofiorine from 30:564 (+)-N-formyldehydroovigerine from 30:563 (+)-N- formylnornantenine from 30:563 (+)-N- formylovigerine from 30:563 (+)-N-hydroxyhernangerine from 30:564 (+)-N-methyl-6,7-dimethoxyisoquinolone from 30:564 (+)-N-methylactinodaphnine from 30:564 5,6-Dimethoxy-N-methylphthalimide from 30:563 6,7-dimethoxy-N-methylisoquinoline from 30:563 7- formyldehydrohemangerine from 30:563 7-formyldehydronomantenine from 30:563 7-formyldehydroovigerine from 30:563 7-hydroxy-6-methoxy- 1methylisoquinoline from 30:564 atheroline from 30:563 backebergine from 30:563 dehydrohemandaline 30:563 demethylsonodione from 30:563 hernandonine from 30:564 hemangerine from 30:564 hemanymphine from 30:564 laetanine from 30:564 laudanosine from 30:564 lindearpine from 30:564
373 monoterpene from 30:569 N-(N-methylcarbamoyl)-Omethylbulbocapnine from 30:564 N-formylnornantenine from 30:563 N-hydroxyovigerine from 30:564 N-methylcorydaldine from 30:564 sterols from 30:569 Hernandia beninensis sp. 30:560 Hernandia bivalves sp. 30:560 Hernandia catalpifolia sp. 30:560 Hernandia cordigera 5:485,561; 30:562-566,568,569 (-)-yatein from 30:569 (+)-actinodaphnine from 30:563 (+)-hernagine from 30:563 (+)-isoboldine from 30:564 (+)-isocorydine from 30:564 (+)-laurotetanine from 30:564 (+)-nandigerine (hernangerine) from 30:565 (+)-neolitsine from 30:565 (+)-N-methylactinodaphnine from 30:564 (+)-N-methyllaurotetanine from 30:565 (+)-norisocorydine from 30:565 (+)-nornantenine from 30:565 (+)-ovigerine from 30:565 (+)-reticuline (S)-reticuline from 30:566 5'-methoxypodorhizol from 18:561;30:569 5'-methoxyyatein from 30:569 anthricin from 30:568 bursehernin from 30:568 cordigerin from 30:568 hernandin from 30:569 podorhizol from 30:569 Hernandia cubensis sp. 30:560 Hernandia didymantha sp. 30:560 Hernandia drakeana sp. 30:560 Hernandia guianensis 30:562-566, 568-570 (+)-actinodaphnine from 30:563 (+)-hernovine from 30:564
(+)-laurotetanine from 30:564 (+)-nandigerine (hernangerine) from 30:565 (+)-ovigerine from 30:565 (+)-reticuline from 30:566 acetylpodophyllotoxin from 30:568 anthricin from 30:568 bursehernin from 30:568 N-methylhernovine from 30:565 N-methylnandigerine from 30:565 picropodophyllin from 30:569 podorhizol from 30:569 stigmasterol from 30:570 [3-sitosterol from 30:570 Hernandiajamaicensis sp. 30:560 Hernandia mascarenensis sp. 30:560 Hernandia moerenhoutiana 30.561,597 antimalarial activity of 30:561 antioxidant activity of 30:561 biological activities of 30:562 cytotoxic activity of 30:561 spasmolytic activity of 30:561 to retain placenta 30:561 to treat malaria 30:561 use in morning sickness 30:561 use in postpartum hemorrhage 30:561 use in treament of malaria 30:597 use in treament of morning sickness 30:597 use in treament of postpartum hemorrhage 30:597 Hernandia nukuhivensis sp. 30:560 Hernandia nymphaeifolia 26:212; 30:561,563-570,597 atheroline from 30:563 biological activities of 30:562 3-cyano-4-methoxypyridine from 30:567 dehydrohernandaline from 30:563 (-)-deoxypodophyllotoxin from 26:218;30:568 5,6-dimethoxy-N-methylphthalimide from 30:563 (+)-epiaschantin from 26:218;
374 30:568 (+)-epimagnolin from 26:218; 30:568 (+)-epiyangambin from 26:218; 30:568 7-formyldehydrohernangerine from 30:563 7- formyldehydronornantenine from 30:563 7-formyldehydroovigerine from 30:563 hernandial from 30:567 hernandonine from 30:564 hernanymphine from 30:564 (-)-hemone from 30:569 (+)-hernovine from 30:564 7-hydroxy-6-methoxy- 1-methyl lisoquinoline from 30:564 6~x-hydroxystigmast-4,22-dien-3one from 30:570 6~x-hydroxystigmast-4-en-3-one from 30:570 3~-hydroxystigmast-5,22-dien-7one from 30:569 3 [3-hydroxystigmast-5-en-7-one from 30:570 (-)-6'-hydroxyyatein from 30:569 (+)-isocorydine from 30:564 (+)-laurotetanine from 30:564 (+)-magnoflorine from 30:564 5'-methoxypodorhizol from 30:569 N-(N-methylcarbamoyl)-Omethylbulbocapnine from 30:564 (+)-nandigerine (hernangerine) from 30:565 (+)-N-hydroxyhernangerine from 30:564 N-hydroxyovigerine from 30:564 N-methylcorydaldine from 30:564 N-methylhernovine from 30:565 (+)-N-methyllaurotetanine from 30:565 (+)-N-methylovigerine from
30:565 (+)-nornantenine from 30:565 northalifoline from 30:565 nymphaeol C from 30:567 (-)-nymphone from 30:569 ovigeridimerine from 30:566 (+)-ovigerine from 30:565 ovihernangerine from 30:566 oviisocorydine from 30:567 7-oxohernagine from 30:565 oxohemandaline from 30:565 oxonantenine from 30:566 stigmasta-4,22-dien-3-one from 30:570 (+)-thalicarpine from 30:567 thalifoline from 30:566 to retain placenta 30:561 to treat malaria 30:561,597 use in postpartum hemorrhage 30:561,597 use in treament of morning sickness 30:597 (+)-vateamine-2' 13-N-oxide from 30:567 (-)-yatein from 26:218;30:569 ~-sitosterone from 30:570 Hernandia obovata sp. 30:561 Hernandia olivacea sp. 30:561 Hernandia ovigera 5:485;30:563-569 (-)-deoxypodophyllotoxin from 30:568 (-)-dimethylmataire sinol from 30:568 (-)-yatein from 30:569 (+)-epimagnolin A from 30:568 (+)-epimagnolin from 30:568 (+)-epiyangambin from 30:569 (+)-nandigerine (hemangerine) from 30:565 (+)-ovigerine from 30:565 (+)-thalicarpine from 30:567 (7R,SS,7'R,8'R)-(+)-7'-acetyl-5 'methoxypicropodophyllin from 30:567 ( 7R, 8S,7'R, 8 'R)-( +)-7 '-acetylpicropodophyllin from 30:568 1,2,3,4-dehydro de oxypodophyllotoxin from 30:568 1,2,3,4-dehydropodophyllotoxin
375
from 30:568 5'-methoxypodorhizol from 30:569 5'-methoxyyatein from 30:569 6,7-demethylenedeoxypodophyllotoxin from 30:568 6,7-dime tho xy-N-methylisoquinoline from 30:563 anthricin from 30:568 bursehernin from 30:568 caruilignan C from 30:568 dehydrothalicarpine from 30:566 deoxypicropodophyllin from 30:568 desoxypicropodophyllin from 18:600 diasesartemin from 30:568 diayangambin from 30:568 epiaschantin from 18:600 epimagnolin from 18:600 hernandin from 30:569 hernandonine from 18:600; 30:564 hemolactone from 30:569 isohernandion from 18:600 N-methylcorydaldine from 30:564 oxocrebanine from 30:565 oxothalicarpine from 30:567 ~-hydroquinone from 30:567 podophyllotoxin from 30:569 podorhizol from 30:569 Hernandia ovigera var. mascarenensis 30:562-565,568,569 (-)-yatein from 30:569 (+)-actinodaphnine from 30:563 (+)-epimagnolin from 30:568 (+)-hernagine from 30:563 (+)-hernovine from 30:564 (+)-nandigerine (hemangerine) from 30:565 bursehernin from 30:568 hemandonine from 30:564 N-methylnandigerine from 30:565 Hernandia peltata 20:522;30:562,564, 566-569 (-)-laetine from 30:564 (-)-yatein from 30:569
(+)-6-northalicarpine from 30:566 (+)-ambrimine from 30:566 (+)-efatine from 30:566 (+)-epiaschantin from 30:568 (+)-epimagnolin from 30:568 (+)-epiyangambin from 30:569 (+)-hebridamine from 30:566 (+)-malekulatine from 30:566 (+)-reticuline (S)-reticuline from 30:566 (+)-thalicarpine from 30:567 (+)-thalicarpine-2 '-N-oxide from 30:567 (+)-thalmelatine from 30:567 (+)-vanuatine from 30:567 (+)-vilaportine from 30:567 6(x,7-dehydrothalmelatine from 30:566 bursehernin from 30:568 epieudesmin from 30:568 vateamine from 30:567 Hernandia rostrata sp. 30:561 Hernandia sonora 30:562-569 (+)-corytuberine from 30:563 (+)-hernagine from 30:563 (+)-hernandaline from 30:563 (+)-malekulatine from 30:566 (+)-N-formyldehydroovigerine from 30:563 (+)-N-formylnornantenine from 30:563 (+)-N-formylovigerine from 30:563 (+)-N-methyl-6,7-dimethoxyisoquinolone from 30:564 (+)-ovigerine from 30:565 5'-methoxypodorhizol acetate from 30:569 5-methoxypodophylloton acetate from 30:569 5-methoxypodophyllotoxin from 30:569 acetylpodophyllotoxin from 30:568 anthricin from 30:568 atheroline from 30:563 backebergine from 30:563 dehydrohemandaline from
376
30:563 demethylsonodione from 30:563 hernandin from 30:569 hernandonine from 30:564 hemangerine from 30:564 isovanillin from 30:567 N-formylnornantenine from 30:563 N-methylhernangerine from 30:565 norsonodione from 30:565 picropodophyllin from 30:569 podophyllotoxin from 30:569 sonodione from 30:566 Hernandia sp. 30:561,562,588,589, 594,597 activity in antiplatelet aggregation turbidimetry assay 30:594 activity in human murine cancer cell line 30:589 activity in human tumor xenograft system 30:589 activity in mouse model 30:589 antimalarial activities of 30:588 antioxidant activity of 30:597 antiplatelet aggregation activity of 30:588 anti-tumor activity of 30:589 benzenoids from 30:562 biological activities of 30:562 cancer chemopreventive activity of 30:588 constituents of 30:562 cytotoxic activity of 30:588, 589,597 dehydrohernandaline from 30:594 (-)-deoxypodophyllotoxin from 30:595 (+)-epiaschantin from 30:595 flavonoids from 30:562 hernangerine from 30:594 (-)-hernone from 30:595 (+)-hernandaline from 30:594 in vitro 30:588 in vivo 30:589 inhibitory effects of 30:594 isoindole from 30:562
isolates from 30:594 isoquinoline alkaloids from 30:562 isovanillin from 30:594 (+)-laurotetanine from 30:594 lignans from 30:562 (+)-malekulatine from 30:594 monoterpenoids from 30:562 N-methylhernangerine from 30:594 (+)-ovigerine from 30:594 7-oxohernagine from 30:595 phytochemical studies of 30:597 pyridine from 30:562 (+)-reticuline from 30:595 role in morning sickness 30:561 role in placenta 30:561 role in postpartum hemorrhage 30:561 spasmodic activity of 30:597 sterols from 30:562 (+)-thalicarpine from 30:595 to treat malaria 30:561 (+)-vateamine-2' [3-N-oxide from 30:595 (-)-yatein from 30:595 Hernandia stenura sp. 30:561 Hernandia stokesii sp. 30:561 Hernandia tahi' nsis sp. 30:561 Hernandia tem,,'ii sp. 30:561 Hernandia voyronii 30:561,562, 564-566,569,597 (-)-laetine from 30:564 (-)-pallidine from 30:566 (-)-pallidine from 30:566 (-)-yatein from 30:569 (+)-6-northalicarpine from 30:566 (+)-ambrimine from 30:566 (+)-efatine from 30:566 (+)-epiaschantin from 30:568 (+)-epimagnolin from 30:568 (+)-epiyangambin from 30:569 (+)-hebridamine from 30:566 (+)-malekulatine from 30:566 (+)-N-methyllaurotetanine from 30:565 (+)-norisocorydine from 30:565 (+)-perillaldehyde from 30:569
377
(+)-reticuline from 30:566 (+)-thalicarpine from 30:567 (+)-thalicarpine-2'-N-oxide from 30:567 (+)-thalmelatine from 30:567 (+)-vanuatine from 30:567 (+)-vilaportine from 30:567 6ct, 7-dehydrothalmelatine from 30:566 antimalarial activity of 30:561 antioxidant activity of 30:561 biological activities of 30:562 bursehernin from 30:568 cytotoxic activity of 30:561 epieudesmin from 30:568 herveline A from 30:566 herveline B from 30:566 herveline C from 30:566 herveline D from 30:566 laetanine from 30:564 laudanosine from 30:564 lindearpine from 30:564 norpredicentrine from 30:565 ocobotrine from 30:565 spasmolytic activity of 30:561 to retain placenta 30:561 to treat malaria 30:561 use in morning sickness 30:561 use in postpartum hemorrhage 30:561 use in treament of malaria 30:597 use in treament of morning sickness 30:597 use in treament of postpartum hemorrhage 30:597 vateamine from 30:567 Hernandiaceae 18:558 Hernandin 18:579-594 synthesis of 18:579-594 Hernandion 18:552,555 from Hernandia ovigera 18:552 Hernandonine 30:564,589 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:589 (+)-Hernandulcin 15:14-16
6S, l'S-Hernandulcin 15:14 (+)-Hernaudulcin 27:13,21 structure of 27:21 Herniaria fontanesii 26:52,54 litholytic properties of 26:52,54 Herniaria glabra 26:50,51 Herniaria hirsuta 26:50 in arrthritis 26:50 in infections of urinary tract 26:50 in infections of respiratory tract 26:50 in kidney disorders 26:50 in neural catarrh 26:50 in neuritis 26:50 in purifying blood 26:50 in rheumatism 26:50 Herniaria saponins A-D 26:50-52 Herniarin 7:204,205,224;18:974,976; 23:354 Hernolactone 18:554,565,569,566 from Hernandia ovigera 18:569 (-)-Hernone 26:212,199;30:569,587, 590,595 activity in human cancer cell lines 30:589 as platelet aggregation inhibitor 30:594 cytotoxicity of 26:212 cytotoxic effect of 30:589 (+)-Hernovine 30:564,589 cytotoxic effect of 30:589 Heroin 18:48 Herpes infection 30:400,401 role of vericella-zoster virus in 30:400 Herpes simplex virus 26:223 ;30:394, 395,400,412 cause of 30:394 inhibitor of 30:395 type 1 (HSV-1) 30:394,400 virus type II (HSV-2) 30:394, 400 Herpes simplex virus type 1 (HSV-1) 30:743,752 antiviral activity 30:743 Herpes simplex virus type II 30:752
378 Herpestis monniera 22:513 for epilepsy and noctumal epilepsy 22:513 Herpesviridae family 30:401 infections caused by 30:401 Herpetomonas curzi 2:298 Herpetomonas mmuscarum 2:298,301 Herpetomonas samuelpessoai 2:298; 26:138 polysaccharides in 2:299-301 Hertellin A 23:403 Hertellin C 23:403 Herveline A 30:566,583,597 13C NMR of 30:584 ~H homonuclear correlation spectroscopy (COSY) of 30:584 1H NMR of 30:583,584 EIMS of 30:584 heteronuclear multiple-bond coherence (HMBC) spectrum of 30:584 heteronuclear multiple-bond quantum coherence (HMQC) spectrum of 30:584 in murine model 30:597 in vivo 30:597 molecular formula of 30:583 UV absorptions of 30:583 Hervelines A-D 30:595,596 antimalarial activity of 30:595 antiplasmodial activity of 30:596 Hesperethusa crenulata 22:522 for epilepsy 22:522 Hesperetin 25:469,541,618;26:757,762 Hesperidin 22:325,423,429,436;23:747; 26:744,745,752,759,766,768 Hesperidin (3',5,7-trihydroxy-4'methoxyflavanone-7-rutinoside) 29:579 effects on ACE 29:579 Hesperidinase 7:270;25:210 Hesperiphona vespertina 5:836;8:151, 152;9:152 hemoglobin components of 5:836 of ot-cedrene 5:790 of artemisinin 5:25,26 of angelic acid 5:778
oftiglic acid 5:778 of 7-hydroxyfrullanolide 9:152 spectra of 8:151,152 HETCOR 21:764;26:11,13,34,37 ofbisdesmoside 26:41 ofdianchinenoside E&F 26:34 of SAPO 26:30,41,50 Heteonuclear correlation 21:764 Heterakis spumosa 26:482 Hetero Diels-Alder reaction 16:654 addition of 16:654 approaches to 16:456 asymmetric 11:260-267 diastereoselective 12:424,425 enantioselective 11:260-267 for nepetalactone synthesis 4:604,605 for tylophorine synthesis 4:604,605 gephyrotoxin 223AB by 4:606 gephyrotoxin by 4:606 iminodienophile in 4:604,605 intramolecular 6:449;14:757, 758;19:43,223 intramolecular Lewis acid catalysed 1:553 lysergic acid by 4:604,605 monomorine I by 4:606 of 2-methoxybutadiene 12:257 oxazoles in 4:604 pyran adduct from 12:257 reaction of 16:439 tetrazines in 4:604 triazines in 4:604 using nitroso dienophiles 1:378 with ethyl glyoxalate 12:257; 13:69,177,187,490,625,757,758 [3-amino acid by 12:158 Hetero Diels-Alder type cycloaddition 24:235 1 [3-Heteroatom-substituted carbapenems 12:165 synthesis of 12:165 Heterobasidion annosum 21:212 Heterocentron roseum 23:404,405 Heteroclitin F&G 26:259 Hetero-Cope rearrangement 8:205 Heterocyclic bicyclic substrate 17:497
379 Heterocyclic compound 17:614-622 semi-synthesis of 17:614-622 N-Heterocyclic compounds 12:445 Heterocycloaddition 1:359-392 Heterodera 26:429,432 Heterodera cajani 26:469 Heterodera glycines 26:429,454,456, 466,467,473,477 Heterodera rostochiensis 26:437 Heterodera schuchiti 26:481 retro-Hetero-Diels Alder reaction 26:113 Heterodienophiles 4:143 in D-allo-threonimal 4:143 in Diels-Alder reaction 4:563 Heterolytic dissociation 6:307,308 Heterolytic fragmentation 13:575 Heteromercuration 1:382 ofcarbamates 1:382 Heteromorpha trifoliata 7:415;21:600; 22:97; 23:341 Heteronema 6:23 halopuupehenones from 6:23 puupehenones from 6:23 Heteronuclear correlated spectroscopy (HETCOR) 5:4,749;30:587 of (-)-hernone 30:587 Heteronuclear correlation (HETCOR) 23:27 Heteronuclear Multiple Bond (HMBC) Connectivity spectra 9:147-153 of griffithine 9:149,150 Heteronuclear multiple bond correlation (HMBC) 23:27 Heteronuclear multiple-bond coherence (HMBC) 30:584 ofherveline A 30:583 Heteronuclear multiple-bond quantum coherence (HMQC) 30:584 ofherveline A 5:314;21:764; 30:583 Heteronuclear shift correlated spectra 9:127,151-154,156-157 Heteropappus altaicus 21:634,660 Heteropappus biennis 21:660 Heterophyllae 7:205 coumarine-hemiterpene ethers in 7:205 Heterophylliin A 23:403
Heterophylliin B 23:403,410 Heterophylliin G 23:403 Heterophyllin 28:230 biological activity of 28:230 Heteropolysaccharides 5:289,290,292, 294 Heteropora alaskensis 17:90,92 Heteropsylla cubana 21:595 Heteropyxis natalensis 21:599 Heterorhahditis nematodes 26:471 Heterostilbene photocyclization 3:355 Heterotropa takaoi 17:348 Heterotrophic cell lines 7:205 Heteroxanthin 6:150 Heteroxenia fuscescens 21:282 Heteroyohimbine alkaloids 25:30 Hexaacetate 6:400 of 2,2-dideoxy-2,2'-diphtalimido,13-trehalose 6:400 Hexabranchus sanguineus 17:16,19:609 Hexacarbonyldicobalt 12:175 5,9-Hexacosadienoic 25:721 (5Z,9Z)-5,9-Hexacosadienoic 26:82 total synthesis of 26:82 5,5 '-Hexadecamethylene- 1,1 ',3-trihydroxy-4,3'-diphenylether 30:136 structure of 30:136 12-O-Hexadecanoyl- 16-hydroxyphorbol-13-acetate (HHPA) 25:45 induced edema inhibition (HPA) 25:46 (Z)-9-Hexadecenoic acid 26:70 methanolysis of 26:65 Hexadecyltrimethylammonium hydroxide (CTAH) 18:832 6-Hexadecyn- 1-ol 2:15 CI(NO) spectrum 2:15 3,4,5,6,18,19-Hexadehydroochropposinine 1:124 Hexadeuterated abscisic acid 27:353 Hexadeutrarated reserpine 25:9 (2E,4E)-2,4-Hexadienoic acid (sorbic acid) 10:149 Hexaenal 6:264-267 acylation of 6:264-267 from N-acetyl amphotericin B methyl 6:264-267 Hexaenoic acid 9:568
380 Hexaflouroacetylacetonate derivative 16:384 Hexafluoro-25-hydroxy-vitamin D2 derivatives 9:518 Hexaglycosides 7:272,278,281,288-290 Hexahydrobenzofuran component 12:24 of avermectins 12:24 parsons approach for 12:24 (-)-Hexahydrocannabinol 19:215 9-nor-9-OH-Hexahydrocannobinol (HHC) 30:195,196 analgesic activity of 30:195 structure of 30:197 Hexahydrocurcumin 17:363,368 (S)-Hexahydrocurcumin 17:365 Hexahydrodibenz [d,g] azecines 6:492, 493 [1] benzothieno analogues of 6:492 from dibenzothieno analogues of 6:492 synthesis of 6:492,493 (S)-Hexahydromandelic acid 6:291,292 Hexahydronaphthalene portion of compactin 11:340-343 Hexahydronaphthalene portion of mevinolin 11:343-345 Hexahydroporphinoids 9:603 Hexahydroporphyrins 9:605 Hexahydroproaporphines 2:255 Hexahydropyrrolocarbazole 1:72 synthesis of 1:72 (+)-a-Hexahydrostepharine 2:256 (+)-[3-Hexahydrostepharine 2:256 Hexahydroxydiphenic acid 15:33 4,4',5,5',6,6'-Hexahydroxydiphenic acid dilactone 27:755 3,5,7,8,3',4'-Hexahydroxyflavone 8-0glucoside) 29:572 313,1613,2113,22cx,23,28-Hexahydroxyolean- 12-ene 18:649 Hexaketide 21:208 Hexalin alcohol 13:601 asymmetric synthesis 13:601 Hexalone 15:241 Hexamer 8:369,370 cyclization reaction of 8:369,370
Hexamethyl phosphoric triamide 11:353 Hexamethyl phosphoric triamide (HMPA) 13:63 Hexamethylphosphoric acid (HMPA) 8:316,318-321,324,326,330,331, 333-336,341-343,346 Hexanortriterpenoid 9:102,297,298 Hexanoyl CoA 11:194 19'-Hexanoylfucoxanthin 6:134,135 CD correlation of 6:137 distribution of 6:134,135 ozonolytic degradation of 6:137 19'-Hexanoyloxyfucoxanthin 6:142,143 19'-Hexanoyloxyisomytiloxanthin 6:142,143,151 19'-Hexanoylparacentrone 6:136 Hexapeptide 10:289;25:887 cyclization of 10:289 Hexapeptide biotratamide 25:878 Hexaphenylhydrazone 9:580,581 Hexaploid 22:608 Hexaprenyl-hydroquinone sulfate 28:676 as H+/K+-ATPase inhibitor 28:676 Hexapyranose nucleosides 4:6 in synthesis of 4:6 deoxynucleosides 4:237 Hexasaccharides 7:31 trans-Hexenal 6:282,284 synthesis of 6:282,284 Hexepi-uvaricin 18:207-211 synthesis of 18:207-211 Hexitols 7:181 Hexodialdopyranoside derivative 4:171 Wittig olefination of 4:171 Hexokinase 7:387 Hexopyranose derivatives 10:426-428 Hexopyranose nucleosides 4:222-225 synthesis of 4:222-225 Hexopyranose-purines 4:224 Hexopyranosyl-pyrimidines 4:224 Hexosamines 22:441 fl-Hexosaminidase 25:939 3-Hexyl-4,5-dithiacycloheptanone 25:842 3-Hexyl-5-methylindolizidine 27:241 diastereomers of 27:241
381 (5Z,9Z)-3-Hexyl-5-methylindolizidine 6:450,451 synthesis of 6:450,451 (+)-Hexylitaconic acid 21:240 Heynea trijuga 2:267 (-)-Heyneanine 5:127 (-)- 19S-Heyneanine 5:127 (+)-Heyneanine 5:127 Heyneanine 9:171 Heyneanol A 26:568 Hezahydrozydiphenic acid 746 Hg(H) mediated Ritter reaction 11:281, 282 m-HHA 25:925 HHPA 25:55 inhibitory effects on 25:55 HHPA induced edema (HPA) 25:45 HHPA-induced inflammation 25:56 Hibiscones A-D 7:185,186 Hibiscoquinones A-D 7:185,186 Hibiscus abelmoschus L. 22:522 for hysteria 22:522 Hibiscus rosa-chinensis 7:180,183,195; 28:400 Hibiscus tiliaceus 7:185 Hibiscus vitifolis 29:572 Hiburipyranone 15:386 9,11-Hidechtoro- 13-demotheylisodysidenin 25:889 (+)-313-Hidroxinagilactone F 28:503 synthesis of 28:503 Higenamine 21:57 High dilution technique 11:153,154 High fat-diet-treated group 27:401 High performance liquid chromatography (HPLC) 2:368,375,393, 397,404;5:621,622,624,648-650; 9:460-464 High pressure technique 4:121 [4+2] cycloaddition by 4:121 in Diels-Alder reaction 4:112 High resolution mass spectrometry 21:584 High sugar diet-treated group 27:410 High TEQ 30:764 High-accumulating lines 7:98-103 Higher plants 7:121-123 gene transfer in 7:121-123
High-fat diet-induced model 30:80 of obesity 30:80 High-fat diet-induced obesity 30:82 prevention of 30:80,82 High-performances liquid chromatography 21:537 High-resolution electron impact mass spectrometry (HREIMS) 30:570 of demethylsonodione 30:570 High-temperature short-time (HTST) treatment 23:786 Hikizimycin 1:398,410-417 ;4:241,245; 11:430,449;26:493 Hikosamine 11:449 Hilbert-Johnson reaction 1:399,400; 4:223,224,230,239 Himandravine 21:56 Himax 28:416 acaricidal action of 28:416 against demodectic mites 28:416 against psoroptic mites 28:416 against sarcoptic mites 28:416 Himbacine 21:56;22:19 Himerometra robustipinna 7:266 Himeyoshin 7:233 Himi-ketal formation 2:237,238 Hinckdentine A 17:88 Hincksinoflustra denticulata 17:85,88 (+)-Hinesol 16:239 Hinge-peptide 18:930-958 Hinokinin 18:566;26:216,231 (-)-Hinokinin 26:192,215,216 Hinokiol 2:403;29:101 activity in CRG bioassay system 29:101 Hinokitiol 21:621 Hippamine 26:610,614 Hippeastrine 22:522,539 Hippeastrine 26:614 Hippeastrum sp. 26:614 Hippeastrum vittatum 22:522 Hippocampal neurons 22:26;30:376 in infantile autism 30:376 morphology of 30:376 Hippocampus 22:508,509 Hippocasculin 7:143 from Aesculus hippocastanum 7:143 Hippocratea 18:741,754;23:651,652
382
Hippocratea indica 5:749 Hippocratea volubilis 30:661,646 lupane caffeoyl esters from 30:646 volubilide from 30:661 Hippocrateine I 23:680 Hippocrateine II 23:680 Hippocrepis balearica 19:117
Hippocrepis comosa 117 Hippodiplosia insculpta 17:90,92 Hippospongia A-F 25:688
Hippospongia metachromia 5:430 Hippospongia sp. 5:432;25:698,721, 871;28:690 Hippospongin 3:157,158 Hippuric acid 9:387;25:928,929 Hiptagamadablota 19:117 Hiptage benghalensis 22:522 for epileptic fits 22:522 Hiptagin 27:522 Hirama synthesis 12:15,16 biomimetic 12:16 of avermectin oxahydrindene subunit 12:15,16 Hiravanone 23:552 Hircinol acid 23:342 HIRE 24:951-954 antibiotic activity of 24:953-954 bioactive compounds from 24:951-954 bioactivity of 24:951-954 Hirsutanonol 25:543 Hirsutene 3:7,12;22:195,201 synthesis of 3:7,12,13,17,18, 20,22,40,65;4:588;13:34-37 (+)-Hirsutene 4:588 Hirsutenone 25:543 Hirsutic acid 3:5,7,12,65 (+)-Hirsutine 13:67 Hirsutine 21:52,79;25:31,32 chromotropic and oxidole alkaloids 25:32 His215 family inhibitors 26:368 Hispaglabridin A 28:228 biological activity of 28:228 Hispidulin 7:227;19:773;30:750 structure of 30:750 Hispidulin-7,4'-disulphate 5:655 Hispidulin-7-sulphate 5:655
Histamine 15:328;21:10,14,19,50,660; 22:111,136,437;25:516,520,532,536, 538,612,613,701,719;30:192 as pain mediator 30:192 from vessels 30:192 Histamine induced edema 25:46 Histamine production 25:611 Histamine receptor 25:611,34 Histamine release 25:47 inhibition of 25:47 Histamine release inhibition 23:357; 24:914-917 by coumarine 23:357 by oosponal 24:914-917 of Morus spp. 24:914-917 Histamine release inhibitor 28:257,293 polyphenols as 28:257,293 Histamine secretion 25:936 Histamine/peptide leukotriene C4 (LCT4) 25:275 Histamine-induced hind paw edema 26:401 Histanecine 19:149 isolation of 19:149 necine base 19:149 Histidine 22:20;25:334,335,526,813; 27:78 Histidine decarboxylase 25:612 Histidine kinases 25:526;27:824 Histidine-rich protein (HRP) 25:334, 342,360 Histidine-rich proteins II and III 25:334 Histiopteris incisa 26:122 Histological examination 27:310 of consuming stevioside effects 27:310 of reproduction tissue 27:310 Histone HI 25:526 Histone phosphorylation 7:387 Histones 30:79 Histoplasma capsulatum 5:307;22:57, 248;23:382 Histoplasma duboisii 5:307 Histoplasma farcinosum 5:307 Histoplasma sp. 5:325,328 Histoplasmosis 2:422 (-)-Histrionicotoxin 16:427,432,453, 19,14,15-16
383 Histrionicotoxins 11:244;18:698,19:3, 14-17;21:70,73 Hitachi high throughput purification (HTP) 29:651 advantages of 29:656 COX-1 inhibition profile by 29:657 for mushroom tyrosinase inhibition 29:656 high-pressure type by 29:654 hit rate in 29:656 HTP/MS spectrum with 29:655 HTP/UV chromatograms with 29:654 via chromatography system 29:654 Hitachimycin 10:153;23:51 HIV (human immuno deficiency virus) 7:12 HIV- assay 19:757 HIV enzymes 30:397 HIV reverse transcriptase 30:397 HIV integrase 30:397 HIV infection treatment 30:396 role of carbohydrates in 30:396 role of sulphated polysaccharide (PS) in 30:396 HIV infections 30:396 chemotherapy of 30:396 HIV inhibition 23:704;30:399 by salaspermic acid 23:704 in vitro 30:399 HIV inhibitory activity 28:121 of equisetin 28:121 HIV inhibitory effects 23:706 ofbetulinic acid 23:706 HIV integrase (IN) 25:941,942;30:226 against AIDS 30:226 mechanism of action 30:226 HIV protease 30:397 role in integration 30:397 HIV replication cycle 30:226 role ifintegrase in 30:226 role ofprotease in 30:226 role of reverse transcriptase in 30:226 HIV therapy 30:397 dextran sulphate in 30:397 pentosan sulphate in 30:397
chondroitin sulphate in 30:397 heparin in 30:397 HIV whole cell assay 19:757 HIV-1 22:675;30:397 inhibitor of 30:397 in vitro 30:397 HIV-1 IN inhibitor 30:228 trifluoromethyl pharmacophore as 30:228 HIV-1 infected H9 cells 30:226 lithospermic acids effect on 30:226 HIV-1 infection 30:399 inhibitory effects on 30:399 HIV-1 integrase 30:226 effect of natural polyphenols on 30:226 HIV-1 integrase inhibition 30:226 in vitro 30:226 HIV-1 integrase inhibitors 30:218,227 lithospermic acid A type of 30:227 lithospermic acid B type of 30:227 HIV-1 p24 antigen 30:396 inhibitor of 30:396 HIV-1 protease 29:574 absinthin (guaine sesquiterpene dimer) effects on 29:574 absintholide (guaine sesquiterpene dimer) effects on 29:574 HIV-1 protease inhibitor 24:489 indinavir as 24:489 HIV-1 reverse transcriptase (RT) 28:702 clathsterol against 28:702 HIV-1 RT inhibition 26:224 by anolignan A&B 26:224 HIV-protease 25:941,942 HIV-protease inhibitor 24:489 ritonavir as 24:489 saquinavir as 24:489 HIV-reverse transcriptase inhibitor 30:412,400 Hiyama reagent 12:36 Hiyama-Ozaki reaction 3:99 HK-mediated neurotoxicity 26:992 HL-60 cells 22:616,617 HL-60 leukemia cell 21:637
384
HLADH 17:479,481 HLADH-catalyzed reactions 17:483 HMB (hydroxymethylbilane) 9:591, 592,595 HMBC 21:764,767 HMBC and NOE correlations 28:26 of 5,7,2 ',4'-tetrahydroxy-3geranylflavone 28:26 HMBC correlations 26:9,13,15,21,25, 29,34 ofbisdesmoside 26:41 of dianchinenoside E 26:34 of SAPO 26:30,41,50 of saponarioside C 26:15,25 of saponaside A 26:21 ofvaccaroside D 26:29 HMG-CoA reductase 5:407;7:108,109, 111,112;15:450 HMGR 24:373-376 role of cholesterol oxides 24:351-398 HMPA 19:415-416 HMPT 26:1091,1092 antimicrobial activity of 26:1091,1092 HMQC 21:764,767 HMQC/HSQC experiment 26:11,34,37 ofbisdesmoside 26:41 ofdianchinenoside E&F 26:34 of SAPO 26:30,41,50 HMR1826 21:176,177 preclinical development of 21:176 HMTP 26:1099 antimicrobial activity of 26:1099 Ho oils 25:140 HOABA 27:346 formation of 27:346 exo-Hobartin- 15-ol 11:299,300 Hobartin- 19-ol 11:305 aristolasicol from 11:305 aristolasicolone from 11:305 aristolasicone from 11:305 aristotelinine from 11:305 oxidation of 11:309 serratenone from 11:305 sorelline from 11:305 synthesis of 11:309
(-)-Hobartine 11:290 absolute configuration of 11:290 (+)-aristoteline from 11:292-295 biomimetic synthesis of 11:287-291 from Aristotelia serrata 11:278 from (-)-[3-pinene 11:281,282 synthesis of 11:280-283 Hobartine 9:178 Hobartine derivative 11:298,299 19-substituted 11:309,310 synthesis of 11:309,310 Hobartine-aristoteline 11:292-295 transformation of 11:292-295 Hodgkin's disease 4:29;22:343 vinblastine for 14:805 vincristine for 14:805 Hodgkinsin 30:205 antinociceptive activity of 30:205 in pin model 30:205 in thermal model 30:205 Hoffmann degradation 18:51 Hoffmann rearrangement 1:410,411; 3:313;19:14 Hoffmann's cycloaddition 18:257 Hoffmann-LaRoche 28:71 vitamin A synthesis by 28:71 Hoffmann-Loeffler photocyclization 6:437 of N-chloroamines 6:437 Hofmann degradation 6:480,489;9:547, 548;14:771-773,793-795 Hofmann elimination 6:481,488;16:53 Hofmann reaction 14:868 HOHAHA spectrum 26:10,21,29,34 ofbisdesmoside 26:41 ofdianchinenoside E 26:34 of saponariosides A&C 26:10,21 ofvaccaroside D 26:29 Holacanthone 7:396;5:38-41 Holarrhena floribunda 22:523 Holarrhena sp. 26:837 Hollocellulose 7:195 Holometamolous 22:398 Holostane 17:118 Holostanol 7:267,268;28:588 structure of 28:588
385
Holothuria atra 7:269 holothurin A from 7:269 holothurin B from 7:269 holothurin Bl from 7:269 Holothuria edulis 7:269 holothurin A2 from 7:269 Holothuria floridana 7:269 holothurin A~ from 7:269 holothurin A2 from 7:269 holothurin B~ from 7:269 Holothuria floridea 21:315 Holothuria forskali 28:592 Holothuria grisea 7:269 holothurin AI from 7:269 Holothuria leucospilota 7:268;15:87 holothurin A from 7:268 holothurin B from 7:268 holothurin from 7:268 Holothuria lubrica 7:269 holothurin A from 7:269 holothurin B from 7:269 Holothuria mexicana 7:281 ;26:72 Holothuria pervicax 15:92;28:720 ganglioside HPG-8 from 28:720 Holothuria scabra 7:270 Holothuria squamiera 7:269 holothurin A from 7:269 holothurin B from 7:269 Holothuria tubulosa 15:104;17:134 Holothuria vagabunda 7:267,268 Holothuriidae 7:268,280 Holothurin 7:267-282,303;15:87 Holothurin A 21:315;28:592 Holothuria leucospilota 28:592 Holothurin A 7:268 from Holothuria atra 7:268 from Holothuria graeffei 7:269 from Holothuria leucospilota 7:268 from Holothuria lubrica 7:269 from Holothuria squamifera 7:269 LDs0 of 7:280 Holothurin A~ 7:269 from Holothuriafloridane 7:269 from Holothuria grisea 7:269 Holothurin A2 7:269 from Bohadschia graeffei 7:269
from Holothuria edulis 7:269 from Holothuriafloridana 7:269 Holothurin B 7:269 from Holothuria atra 7:269 from Holothuria graeffei 7:269 from Holothuria leucospilota 7:268 from Holothuria lubrica 7:269 from Holothuria squamifera 7:269 Holothurin B! 7:269 from Holothuria atra 7:269 from Holothuriafloridana 7:269 Holothurinogenin 7:267,268 Holothuroidea 7:265,267-282;15:43, 87-94;21:314 Holotoxigenol 7:277,278 Holotoxin A 7:277-279 from Stichopusjaponicus 7:277 Holotoxin A2 7:277-279 Holotoxin B 7:277-279 from Stichopus japonicus 7:277-279 Holotoxin B1 7:277-279 Holotoxin C 7:280 Holotoxins A, AI, B and Bl 15:87 from Parastichopus californicus 15:87 from Stichopusjaponicus 15:87 Holstiine 26:1048 Holton's taxol synthesis 12:220 Homanindole A 25:863 Homarus americanus 19:668 Homatropine 22:732,738 Homidium 26:786 Homoaldol reaction 8:156,157 Homoallylic alcohol 11:346,347 from epoxide 11:346,347 with vinylmagnesium bromide 11:346,347 Homoallylic coupling 10:118 Homoarginine 9:499 Homobautrachotoxin 22:35 25-Homobrassinolide 16:352;19:253, 225 synthesis of 19:258 (+)-Homobuxaquamarine 2:179,2:180, 205 (-)-Homocamphor 16:149
386
(+)-cis-Homocaronic acid 16:221 Homocarotenoids 7:317,318,355-364 25-Homocastasterone 16:337 from acetonide 16:337 ]3-Homochelidone 25:539 (+)-Homochelidonine 14:769,796 from berberine 14:796 synthesis of 14:796 Homochiral (+) synthesis 29:498 by Boyer and Lallemand 29:499 by French research groups 29:498 Homochiral auxiliary 1:578 C2-Homochiral cyclopropenes 14:507, 508 Homochiral diol auxiliaries 1:579-582 Homochiral ketone auxiliaries 1:579, 583,584 Homoconjugated oxo compounds 2:170 Cotton effect of 2:170 helicity in 2:170 Homocoriolic acid 13:315 Homocylindrocarpidine 5:127 Homoditerpene 17:22 Homodolastain 25:3;25:902 28-Homodolicholide 16:335 28-Homodolichosterone 16:335 Homoenolate ions 3:217 from allylic esters 3:217 Homoeriodictyol 7:228;30:746 structure of 30:746 Homoerythrinan alkaloids 3:480-486 synthesis of 3:480-486 Homogeranoitrile bromohydrin 6:64 spirolaureone from 6:64 Homohalichondrins A 5:378,380,382 Homohalichondrins B 5:378,380,382 Homohalichondrins C 5:378,382 Homoharringtonine 21:97;22:29 Homoisoflavan 5:17,18,20,23,24 Homoisopavine base system 6:471 synthesis of 6:471 Homologation 6:32;11:257,258, 462-464;12:82;14:175 Homologous sequences 30:831 of chymotrypsin 30:831 of earthworm chymotrypsinogen 30:831 of F-III- 1(2) 30:831
of human leukocyte elastase (HLE) 30:831 of lugworm chymotrypsinogen 30:831 of pocine pancreatic elastase (PPE) 30:831 of trypsin 30:831 ofU(t)-PA, plasmin 30:831 Homolycorine 20:325,347,353,468; 26:618 25-Homolyphasterol 16:352 Homolytic dissociation 6:307,308 c~-Homonojirimycin 10:544,545 from Omphalea diandra 10:544 Homonojirimycin 11:267 (+)-~-Homonojirimycin 11:431,432 synthesis of 11:431,432 (+)-Homononactate 18:253 Homonuclear 2D J-resolved spectra 9:139,140 Homonuclear correlation spectroscopy (IH-IH COSY) 5:3 Homonuclear Hartmann-Hahn spectroscopy (HOHAHA) 9:146,149, 151-153,158,159 of griffithine 9:149 Homooligomers 27:768 of trans-resveratrol 27:768 Homophthalate 11:119 Claisen condensation of 11:119 with acetoacetate dinion 11:119 Homophthalic acid amide 11:117 (R)/(S)-Homoproline 13:507,508 synthesis of 13:507,508 Homoptera 22:398 Homopterocarpin 20:730,20:774 Homopumiliotoxins 19:52 Homoricinoleic acid 13:315 31-Homorifamcin W 23:61 Homosapiens 21:101 Homostatine derivatives 12:477 Homoteasterone 18:507 from Raphanus sativus 18:507 Homothallin II 21:223 Homothienamycin 8:262 synthesis of 8:262 Homotriterpenes 9:267 Homovanillic acid 22:671
387
Homphymia conferta 25:793 Honey 28:385 formic acid in 28:385 Hongshengma 27:395 Honokiol 26:217,227,240,249,254 inhibitory activity of 26:217 as PAF-induced inhibitor 26:240 Honokiol (lignan) 29:582 effects on MMP 29:582 Honyumine 13:348,349 Hop-17-ene 25:59,65 Hopane triterpenes 22:107 Hopanes 22:95,107 Hopea brevipetiolaris 23:547 Hopea malibato 23:547 Hopeaphenol 23:533;26:561 (-)-Hopeaphenol 26:561 (+)-Hopeaphenol 26:561 Hoppe coupling 10:15 Hordatines 27:765 Hordenine 25:531 Hordeum 29:593 Hordeum lipid transfer proteins 29:593 effects on barley malt cysteine endoproteinases 29:593 Hordeum vulgare 21:91,504;27:191, 765;29:593 Horeau's method 5:146,149;9:25,26,28, 402;12:313;15:76,270,475;20:27; 21:751 Horeau's partial resolution method 5:371 Horhammerinine 2:375 Horminone 20:673 from Salvia acetobulosa 20:673 from Salvia candidissima 20:660 from Salvia multicaulis 20:673 from Salvia napifolia 20:670 from Salvia tomentosa 20:667 from Rabdosia lophanthoides var. gerardiana 15:173 Horminone-18-oic acid 20:661 from Salvia divaricata 20:661 Hormodendrum sp. 5:325 Hormone-activated guanylate cyclase (GC) 25:519 Hormone-activated receptor tyrosine kinase 25:518
Hormone-like substances 6:538 Hormones 18:819-866;19:627-687; 22:25 bioactive conformations of 18:819-866 Hormosira banksii 26:440 Hormosirene 21:305 Homer Bestmann oxidation 8:207 Homer reaction 6:285,286 Horner-Emmons carbon elongations 29:127 in sesquiterpenoids drimane-type synthesis 29:127 Horner-Emmons condensation 1:410, 411;10:13-17,19;11:432;14:129; 16:655;18:288 Horner-Emmons coupling 14:115,123 Horner-Emmons olefination 10:534, 441,442;14:126;16:460;18:288, 633 Horner-Emmons olefination procedure 30:458 for ketene dithioacetals 30:458 Horner-Emmons reaction 1:448,450; 5:828;8:16,209,270,271 ;9:356;10:43; 13:175,210,570;14:593 ;18:481,586; 19:14,45,62;20:567,575,580,585, 588,591,595,596,599,606;30:32 Horner-Wadsworth-Emmons condensation 19:529 Horner-Wadsworth-Emmons olefination 20:567;21:432 Horner-Wadsworth-Emmons reaction 12:30;20:72-74;30:34,46 Horner-Wittig olefination 6:545;9:525; 546;10:157,159,164;16:673 ;19:448; 20:702 Horner-Wittig-type reagent 19:452 Horseradish peroxidase (HRP) 5:497, 498;6:519;14:820,821 ;15:366; 26:1133;30:844 Horsfieldia iryaghedhi 5:753 Horsfieldin 5:753,754 Hortensin 5:14,15 Hortia arborea 4:400 furanocoumarin from 4:398 Hortia regia 22:400
388
Hortiolone 4:396,398 from furanocoumarin 4:396,398 synthesis of 4:396,398 Hoslundal 2:129,2:135 Hoslundia opposita 2:129;22:523 for epilepsy 22:523 for convulsions 22:523 Hoslundin 2:129,133,135 Hoslundiol 2:129,134,135 Host microorganism selectivity 23:42 Hosta longipes 21:643 Hosta plantaginea 21:637 Host-guest complexes 13:328 Host-mediated activity 25:431 of Chlorella vulgaris strain CK 22 (CVs) 25:431 Host-mediated antitumor activity 23:445 of tannic acid 23:445 Host-mediated immuno-modulator 30:768 CVE as 30:768 Host-splenomegaly response 30:4 inhibition by (+)-discodermolide 30:4 Hot CNSL bat process 9:330,331 Hot plate test 30:207,802,804,581 activity of (-)-menthol in 30:207 for determination of antinociception 30:802 ofpeptide 30:804 Houk's "inside crowded" model 12:57 Houk's "outside crowded" model 12:58 Houk's concept 11:240 House dust 24:914-917 contraction with tachyphylaxis 24:914-917 House dust mites 28:417 Actinodaphne lancifolia against 28:419 benzyl benzoate against 28:418 Cinnamomum camphora against 28:419 Cinnamomum japonicum against 28:419
Dermatophagoides farinae against 28:417
Dermatophagoides pteronyssinus against 28:417
Euroglyphus maynei against 28:417
Lindera umbellata against 28:419
Melaleuca acacoides against 28:419
Melaleuca symphycarpa against 28:419
Neolitsea sericea against 28:419 Persia thunbergii against 28:419 Taiwania cryptomerioides against 28:418 tannic acid against 28:418 treatment of 28:418 House procedure 10:308,309 House's conditions 12:46,47 Hovenia dulcis Thumb. 15:36;21:659, 674 ;24:273 ;27:40 gymaemasaponin III from 27:41, 43 gymaemasaponin IV from 27:41, 43 gymaemasaponin V from 27:41, 43 gymnemic acid I from 27:41,42 gymnemic acid II from 27:41,42 gymnemic acid III from 27:41, 42 gymnemic acid IV from 27:41, 42 gymnemic acid V from 27:41,42 gynmemic acid VI from 27:41, 42 gynmemic acid VIII from 27:41, 42 gymnemic acid IX from 27:41, 42 gymnemic acid X from 27:41,42 gymnemic acid XI from 27:41, 42 gymnemic acid XII from 27:41, 42 gymnemic acid XIII from 27:42, 42 gymnemic acid XIV from 27:41, 42 gymnemic acid XV from 27:41, 42,45 gynmemic acid XVI from 27:41,
389 42,45 gymnemic acid XVII from 27:41,42,45 gymnemic acid XVIII from 27:41,42,45 hoduloside I from 27:41 hoduloside II from 27:41 hoduloside III from 27:41 hoduloside IV from 27:41 hoduloside IX from 27:41 hoduloside V from 27:41 hoduloside VII from 27:41 hoduloside VIII from 27:41 hoduloside X from 27:41 hovenoside I from 27:41 jujubasaponm II from 27:41 jujubasaponln III from 27:41 jujubasaponm IV from 27:41 jujubasaponm V from 27:41 jujubasaponan VI from 27:41 jujubasaponin Zizyphus saponin III from 27:41 jujuboside B from 27:41 jujuboside B from 27:41 saponin C2 from 27:41 saponin E from 27:41 saponin H from 27:41 16,17-seco-dammarane triterpene glycoside from 21:659 sitakisoside XIII from 27:41 sitakisoside XVI from 27:41 sitakisoside XVIII from 27:41 sltakisoside I from 27:41 sitakisoside II from 27:41 sitakisoside III from 27:41 sitakisoside IV from 27:41 sitakisoside IX from 27:41 sitakisoside V from 27:41 sitakisoside VI from 27:41 sitakisoside VII from 27:41 sitakisoside VIII from 27:41 sitakisoside X from 27:41 sitakisoside XI from 27:41 sitakisoside XII from 27:41 zlziphin from 27:41 Zizyphus saponin I from 27:41 Zizyphus saponin II from 27:41 Hoveniodulciosides A1,A2,B 1 and B2 21:658
Hovenolactone 27:45,47 structure of 27:47 Hovenosdie I 27:41,45,46 structure of 27:46 Hoxax inella sp. 25:762 Hoya austrulis R. 22:523; for convulsions 22:523 Hoye's 1:672 of (+)-3,3-dibromocamphor 16:135 of levoglucosenone 14:269 with NBS 19:314 Hoye's bromination 1:678 Hoye's procedure 6:56,57 HPA 25:46 y-HPKC 25:61 HPLC 4:283 anion exchange 4:283 for oligonucleotide purification 4:283 of diastereomers 13:280-282 oftryptic peptides 2:34 reversed phase 4:283 HPLC chromatogram 23:748,751,759, 760 ofLollo rosso 23:759 of lemon juice phenolics 23:748 of red lettuce anthocyanins 23:760 of red onoin anthocyanins 23:762 of Romaine lettuce phenols 23:761 of spinach phenols 23:765 of tomato peel phenolics 23:766 m-HPPA 25:925,927 (5Z,8E)-3-Hptyl-5-methylpyrrolizidine 6:445,446 from 3-(5-methyl-2-furyl) propional-dehyde 6:445,446 HREIMS 30:582,584,586,587 of (-)-6'-hydroxyyatein 30:587 of (-)-hernone 30:587 of (+)-N-formylovigerine 30:582 of (7R,8S,7'R,8'R)-(+)-7'-acetyl5 '-methoxypicropodophyllin 30:586 of 7-formyldehydroovigerine 30:581
390
of ernamymphine 30:582 of ovihernangerine 30:584 HRFAB-MS 26:20,33 ofbisdesmoside 26:41 of dianchinenoside E 26:33 of SAPO 26:30,50,41 of saponarioside A 26:20 HRMS 21:584,734 HRP II inhibition 25:336 HRP II mediated hemozoin synthesis assays 25:352 HRV inhibitors 30:407 in vitro 30:407 from Stevia rebaudiana 30:407 HRV replication inhibitor 30:407 in vitro 30:407 mechanism of 30:407 HSV infections 30:401 acyclovir-resistance in 30:401 antiviral medications for 30:401 symptoms of 30:401 HSV-1 24:524;30:402,403 activity of actinoplanic acids against 24:524 antiviral activity against 30:403 in vivo 30:403 inhibitor of 30:402 HSV-1 corneal infection 21:697 therapeutic efficacy against 21:697 HSV- 1 infection 21:694 HSV-1 replication 21:695 inhibitory effect on 21:695 HSV-2 30:402,403 in vitro 30:402 inhibitors of 30:402 HSV-2-virus 4:237;19:289 antiviral activity against 4:237 Co-3-human colon carcinoma 19:289 HT-29 (human colon carcinoma) 30:588,691 activity of (-)-deoxypodophyllotoxin against 30:588 activity of (-)-yatein against 30:588 phenolic triterpenes against 30:691 5-HT3 class receptors 25:529
5-HT3 receptor 27:286 5-HT4 receptor 27:286 Huang-Minlon modification 14:684 Huang-Minlon reduction 14:674,676, 677 Huangqioside E 27:18,35 structure of 27:35 Huangqmyegenin 25:1 25:195 Huangqmyegenin A 25:195 Huangqulyegenin B 25:202 Huangqmyegenin II 25:202 Huangqmyenin 25:184 Huangqmyenin D 25:192 Hudson lactone rule 10:262 Hugonia 26:172 Huiliste 22:560 Huisgen pyrrole synthesis 13:445 Human breast cancer cell line MCF-7 30:314 human cancer cell lines 30:589,590 activity of (-)-deoxypodophyllotoxin in 30:589 activity of (-)-hernone in 30:590 activity of (-)-nymphone in 30:590 activity of (-)-yatein in 30:590 activity of (+)-corytuberine in 30:589 actwity of (+)-epiaschantin in 30:590 actwlty of (+)-epimagnolin in 30:590 actwlty of (+)-epiyangambin in 30:590 actwlty of (+)-hernovine in 30:589 actwlty of (+)-laurotetanine in 30:589 actwlty of (+)-magnoflorine in 30:589 activity of (+)-malekulatine in 30:590 activity of (+)-N- activity of hydroxyhernangerine in 30:589 activity of (+)-N- formylnornantenine in 30:589 activity of (+)-N-formyldehydroovigerine in 30:589
391
activity of (+)-N-formylovigerine in 30:589 activity of (+)-ovigerine in 30:590 activity of (+)-ovihernangerine in 30:590 activity of (+)-vateamine-2'~-Noxide in 30:590 activity of 7-formyldehydrohemangerine in 30:589 activity of 7-formyldehydronornantenine in 30:589 activity of 7-formyldehydroovigerine in 30:589 activity of 7-hydroxy-6-methoxy1-methylisoquinoline in 30:589 activity of 7-oxohernagine in 30:590 activity of demethylsonodione in 30:589 activity of hernandonine in 30:589 activity of hernanymphine in 30:589 activity of N-hydroxyovigerine in 30:589 activity of N-methylcorydaldine in 30:589 activity of N-methylovigerine in 30:590 activity ofthalifoline in 30:590 Human carcinoma 24:6 of nasopharynx (KB) 24:6 Human chemopreventives 30:592 Human colon adenocarcinoma cell cultures 25:903 Human colon carcinoma 23:255,290 Human cytomegalovirus 30:395 inhibitor of 30:395 Human cytomegalovirus (HCMV) 21:646 Human cytomegalovirus protease inhibitors 28:118 bripiodionen as 28:117,118 Human diseases 30:224 aging 30:224 atherosclerosis 30:224 cancer 30:224 cardiac diseases 30:224
diabetes inflammation 30:224 intestinal diseases 30:224 neurodegeneration 30:224 reperfusion injuries 30:224 respiratory disorders 30:224 role of free radicals in 30:224 Human growth hormone 4:271 Human HEK 293 cell line 30:781 biological response of 30:781 Human HL-60 leukemia cells 30:496 differentiation of 30:496 inhibition of 30:496 proliferation of 30:496 Human IgG! Hinge-fragment 18:907-958 Human immunodeficiency virus 7:12, 396;21:149;26:223 ;30:226,395,396, 412 inhibitor of 30:395 Human immunodeficiency virus type-1 25:948 Human interleukin-[3 21:404 Human leucocyte elastase 25:47 inhibition of 25:47 Human leukemia cells 18:269 Human leukocyte elastase 16:727 inhibitor of 16:727 Human leukocyte elastase (HLE) 30:830,831,843 homologous sequences of 30:831 plasminogen activator (u-PA) 30:830 Human lung carcinoma 23:290;30:5 discodermolide against 30:5 A-549(Human lung carcinoma) 30:691 phenolic triterpenes against 30:691 Human medulloblastoma 23:290 Human melanoma 23:255 Human mesangial cell proliferation 30:308 in vitro 30:308 Human monoblastic leukemia cells 30:498 effect of hydroxyurea (HU) 30:498 growth inhibition of 30:498
392
Human monoblastic leukemia U937 cells 30:498 growth inhibition of 30:498 Human nasopharyngeal KB 12:390 staurosporine activity against 12:390 Human neuroblastoma NB- 1 cells 12:390 cytotoxic against staurosporine 12:390 Human neuroblastoma nbla-N-5 cells tamoxifen activity against 12:390 Human neuroblastoma SH-SY-5Y cells 12:390 Human neutrophils 12:390 Human neutropil protein kinase C 12:389 Human onchocerciasis 12:9 ivermectin for 12:9 Human papilloma virus 23:97;26:223; 30:394 pathogenesis of 30:394 cause of hepatocellular carcinoma 30:394 Human papilloma virus type 11 30:406 microbicidal compound against 30:406 Human papilloma virus type 40 30:406 microbicidal compound against 30:406 Human platelets 12:390 study of protein kinase C in 12:390 by staurosporine 12:390 Human rotavirus (HRV) 30:406,412 cause of dehydrating gastroenteritis 30:406 member of 30:406 reoviridae type of 30:406 Human serotonin transporter gene (SLC6A4) 30:376 regulation of neuronal activity 30:376 Human spermatozoa motility 21:675 Human synovial PLA2 25:697 inhibitor of 25:697 Human xenografted carcinomas 19:330
Humantenine 15:472 from Gelsemium elegans 15:472 Humantenine-type oxindole alkaloids 15:472-474 Humantenirine 9:196,197;15:472 Humboldlia vahliana 22:523 use for epilepsy 22:523 Humicola spp. 2:323 et-Humulene 21:586,594 Humulene 3:77,78;6:37,48;13:6;23:545, 852;25:168,170 (+)-africanol from 6:37 (+)-A9~12)-capnellene from 6:48 c~-Humulene epoxide 21:586 Humulones 23:342,348;24:902-904 anti-glycemic effects 24:902-904 anti-hyperglycemic effects of 24:902-904 Humulus lupulus 7:121;14:450;21:521, 584 ;23:342 ;24:902 [3-farnesene from 7:121 eudesm- 11-en-4-ols from 14:450 (-)-selin-11-en-4a-ol from 14:450 Hunnemannia genera 27:163 Hunteria 13:70,93 indole alkaloids 13:70,93 2-Huoro-ABA 27:355 Hup A 21:748-750 clinical trials of 21:750 Huperzia serrata 21:744 (+)-Huperzine A 18:321,324 Huperzine A 21:746-748;22:30 synthesis of 21:746-748 Huperzine B 21:748 Hura crepitans 20:19 Huratoxin 20:19 Hv-CPI phytocystatin 29:593 effects on chymopapain 29:593 effects on ficin papain 29:593 Hyalbidone 17:400 Hyalodendron pyrium 5:305 Hyalodendron sp. 5:305;21:218 Hyalomma anatolicum 28:405 Hyalomma genera 28:404 Hyalomma sp. 28:396,407 Hyalophora cecropia 1:206;22:381 Hyalurnidase-inhibitory activity 25:939
393
Hyaluronidase 25:939 Hyattella 19:568 Hybrimycins 5:615 Hydalhodes 25:391 Hyderabadine 5:124,158 Hydnellum (Hydnum) 29:271 Hydnocarpin 5:496 Hydnocarpus wightiana 5:496 Hydnum suaveolens 29:284 Hydoxybenzoic acid 22:630 pHydractinia echinata 18:701 Hydrangea macrophylla 2:286;13:660; 15:5,30,387;27:7,17 phylloduclin from 13:660;15:30 Hydrangea macrophylla Seringe var. thunbergii 27:17 Hydrangenol 2:288,289,387 Hydrangenol glucoside 2:288,289 a-Hydrastine 1:191,192 synthesis of 1:191,192 Hydrastine 21:69 (-)13-Hydrastine 26:868 (+)[3-Hydrastine 26:868 [3-Hydrastine 1:191,192 synthesis of 1:191,192 13-Hydrastine N-oxide 6:468 1,2-H shift in 6:468 thermally-induced rearrangement of 6:468 Hydration 4:332 mercury catalysed 4:332 of acetylenes 4:332 Hydrato-pyrrhoxanthinol 6:151,152 Hydrazine 1:20 reduction with 1:20 Hydrazine acetate 21:168 Hydrazinolysis 25:438 Hydrazoic acid 22:283 Hydrazone 18:67 Hydrellia sp. 22:401 1,4-Hydride reduction 12:154 Hydride reduction 14:153;19:372 of sulfonates 14:153 [ 1,2]-Hydride shift 10:216,222;19:518 Hydride shift 9:45,46 2,6-Hydride shifts 4:626,627,634,643 in camphor derivative 4:634,643
in rearrangement of camphor 4:626,627 Hydride transfer 17:486-487 6,2-Hydride-shift 4:650,651 trans-Hydrindane 10:51 synthesis of 10:51 Hydrindane 13:24 trans-Hydrindane system 14:552 cis-Hydrindane system 9:526 Hydrindanol 10:55,56 Hydrindanone 9:249-252;10:51,56 in (+)-9-isocyanopupukenanane 6:80 Hydroalanation 10:21,24,29 cis-Hydroazulene 12:251 from tropone 12:251 Hydroazulene mesylates 14:376-379 Hydroazulene sesquiterpenes 14:355-387 Hydroazulene skeleton 1:553 synthesis of 1:553 Hydroazulenes 10:181 Hydroboration 8:470-473,475,478; 10:15;11:83,84,316,317,319;14:456, 681,682;16:472;19:367 highly stereoselective 12:151, 152 of allylic ethers 4:116 of olefin 12:151,152 of vinylic ethers 4:116 regioselectivity 4:116 stereoselective 19:367 to alcohol 12:151,152 Hydroboration-oxidation 14:773,774; 24:203,204,210 Hydrocarbons 27:700 from olive oil 27:700 Hydrochalcones 7:192 Hydrocholeretic effect 26:391,399,415 Hydrocortisone 9:17,411,416,418-423, 428,429;22:122,123 ;25:56,57 e~-acetate 9:17,416 Hydrocotile genera 27:661 Hydrocotyloideae 27:661 Hydrodictyon reticulatum 18:495,507; 19:247 Hydrodicyclopenta [a,d] cyclooctane 1:563-565 Hydroformylation 16:409
394
Hydrogen abstraction 16:41 Hydrogen bonding 17:562 Hydrogen peroxide oxidation 14:324, 325 Hydrogen phosphonate method 4:274-276 of oligonucleotide synthesis 4:274-276 mechanism of 4:275 1,5-Hydrogen shift 1:327 A~-Hydrogenase activity 9:420 stereoselective 16:345 ofazide group 16:78 Hydrogenation 24:36,37,100,101,104, 119,182;30:486 2,3-anti selective 12:35,36 heterogenous 12:36 homogenous 12:35,36 of double bond 19:45;19:307 ofketones 19:27 of methyl acetoacetate 13:72,73 of phenyl sulfone derivative 30:486 of pyranone 19:468 of [3-ketoester 19:29 on naphthalene-Cr (CO)3 complex 4:343,344 stereoselective 12:151,152; 19:296,301 using Adam's catalyst 19:70 1-Hydrogenation 26:66 of 10,13-dimethyl-9-tetradecenol 26:66 Hydrogen-bonding 30:581 of 7-formyldehydroovigerine 30:581 Hydrogenocobyrinic acid 9:601 Hydrogenolysis 6:276,426,435,451,168, 169; 19:6,36,38,42,104,332,362, 367-368,371 ;21:200;30:17 of PMB group 30:17 Hydrogenomonas eutropha 4:439 Hydroindane (bicyclo [4.3.0] nonane) 11:230 Hydroindanone 19:10 cisHydroindolenones 4:17-19 from a'-bromocyclohexenones 4:17-19
Hydrolapachol (2-hydroxy- 1,4naphthoquinone) 26:803 Hydrolysable tannins 23:750;27:840 activity of 27:840 Hydrolysis 1:678,679,682;27:354 asymmetric 1:678,679,682 by Candida cylindracea lipase 1:685 by lipases 1:684,685 by pig liver esterase 1:685 by pig pancreatic lipase 1:685 by Pseudomonas fluorescens lipase 1:685 ofabscisic acid-GE 27:354 of fat 27:402 of N-acetyl (x-amino acids 1:678,679,684,685 acid-catalyzed 11:361 enantioselective 13:54 ofabscisic acid-GE 27:354 of fat 27:402 of phosphate 27:872 photochemical 6:331,333 selective 6:285,286 Hydrolysis products 27:82 of epoxyaldehydes 27:82 Hydrolytic cleavage 12:428-430 Hydrolytic fragmentation 12:198 Hydrolyzable tannins 25:541 Hydronaphthalene 22:253 Hydronaphthalene tosylates 14:368-370 Hydronaphthalene- 1,10-diol monosulfonate esters 14:356 Pinacol rearrangement of 14:356 Hydroperoxide 17:9 R-Hydroperoxide 9:574 Hydroperoxide initiated 22:346 chemiluminescence 22:346 Hydroperoxide dehydrase 9:526,577 Hydroperoxide isomerases 9:577,578 Hydroperoxide lyase 9:577;13:11 Hydroperoxide oxidation 4:559 Hydroperoxides 5:409;16:608 cyctotoxic activity of 5:409 photodecomposition of 16:608 9/13-Hydroperoxo-),-linolenic acids 9:582
395
10-epi-5~-Hydroperoxy-[3-eudesmol 23:811 16-Hydroperoxy-10,12,14-octadecatrienoic acid 27:71 generation of 27:71 9-Hydroperoxy- 10,12,15-octadecatrienoic acid 27:74 by Baeyer-Villiger reaction 27:94 transformation of 27:74 (6S, 7S, 10R)-2-Hydroperoxy-2,6,10trimethyl-7,10-epoxydodeca-3,11dien-5-one 27:594 24-Hydroperoxy-24-vinyl-cholesterol (saringosterol) 10:249 2E-4-Hydroperoxy-2-nonenal (4-HNE) 27:74,75,83 generation of 27:75 25-Hydroperoxy-2c~,313,12~,20Stetrahydroxydammar-23-ene 18:650 5-Hydroperoxy-6,8,11,14-eicosatetraenoic acid (5-HPETE) 5:513,514 13S-Hydroperoxy-9Z, 11E-octadecadienoate 9:563,565 13R-Hydroperoxy-9Z, 12E-octadecadienoate 9:566 13-Hydroperoxy-9Z- 11E-octadecaenoic acid 27:69-71 generation of 27:69,70 Hydroperoxycadiforin 22:653,654; 30:611,612 structure of 30:612 5-Hydroperoxy-eicosatetraenoic acid 26:265 5S-Hydroperoxy-icsatetraenoic acid 9:562 Hydrophobic metabolites 27:447,484 Hydrophobicity 27:333 Hydroprene 10:149;22:395 1,4-Hydroquinone 23:53 Hydroquinone 5:439,440;9:579;25:658 Hydrothermolysis 26:40 Hydroxamates 9:537,580 Hydroxamic acid 1:296;9:549 (S)-Hydroxamic acid 19:11 (4S)-Hydroxmethylbutanolide 6:292 from L-glutamic acid 6:292 from D-ribonolactone 6:292
13-Hydroxy 3or,11-epoxy-apotrichothec9-ene 9:210 c~-Hydroxy acids 1:446,447 as chiral building blocks 1:680,681 3-Hydroxy acids 4:625 as chiral synthons 4:625 ent -8c~-Hydroxy- 13,14-dien- 18-oic acid methyl ester 25:261 w-Hydroxy acids 8:176,233,234,236 cyclization of 8:234 intramolecular esterification of 8:176 lactonization of 8:233,234,236 Hydroxy amino acids 12:431-438 synthesis of 12:431-438 c0-Hydroxy Ct4 30:145 synthesis of 30:145 (R)-2-Hydroxy carboxylates 20:840-842,853 dehydrogenation of 20:840-842 to 2-oxo-carboxylates 20:840-842,853 preparation of 20:842 Hydroxy cinnamoyl-CoA esters 25:652 8-Hydroxy citronellol 25:136 N-Hydroxy compounds 8:376 cis,cis-2c~-Hydroxy costunolide 27:560 3~-Hydroxy costunolide 27:560 7-Hydroxy coumarin 23:337 Hydroxy dithioketal 10:203,204 trans-Hydroxy epoxide 10:205,206 cyclization of 10:205,206 Hydroxy epoxides 10:205-207 cis-Hydroxy epoxides 10:207 [3-Hydroxy ester 1:689-701 as chiral building blocks 1:689-701 from (a-bromoalkyl) boronic ester 11:425 synthesis of 11:425 2-(1-Hydroxy ethyl)-naptho [2,3-b] furan-4,9-dione 20:494 14-Hydroxy ferruginol 20:666 from Salvia montbretii 20:666 3-Hydroxy flavanones 23:798 4,5-cis-3 [3-Hydroxy germacranolide 27:561
396 2-Hydroxy glycal 10:349 4-Hydroxy isopiperitenone 25:151 [3-Hydroxy ketones 1:701-707 Hydroxy ketones 10:205 syn selectivity of 10:205 13-Hydroxy lactone 12:29,30 10-Hydroxy liriodenine 20:483 Hydroxy methylglutarylcoenzyme A synthetase 25:525 2-Hydroxy muconate 10:152 7-Hydroxy muurollene 21:282 4-Hydroxy N-(3,7-octaienly) oxazolidin2-one 12:468 10-Hydroxy octadec-(8E)-enoic acid 13:313 13-Hydroxy octadeca-(9Z, 11E)-dienoic acid 13:311 11-Hydroxy palmitic acid 13:312 Hydroxy pyrrolidinone carboxylate 8:269 713-Hydroxy sandracopimaric acid 20:690 from Salvia heldrichiana 20:690 3fl-Hydroxy sterols ~25:306 16-o~-Hydroxy tubeimoside I 21:732 25-Hydroxy vitamin D2 10:63,65,66, 68,69 synthesis of 10:69 25E,26-Hydroxy vitamin D2 10:65 (24R)- 1ot-Hydroxy vitamin D2 10:66 1a-Hydroxy vitamin D3 10:43,59,69 synthesis of 10:59,69 25-Hydroxy vitamin D3 10:67 4[3-Hydroxy withanolide E 20:214,245 17[3-Hydroxy withanolide K 20:246 16a-Hydroxy-(-)-kauronoic acid 9:397 15-(2-Hydroxy)-isobutyryloxy-micrantholide 29:89 activity in TNFct assay system 29:89 3-(Hydroxy)methylene-2-thioxopyrrolidine (HMTP) 26:1073,1077-1079, 1083,1084,1087,1092,1093,1095, 1096,1099,1100,1102,1103 3fl-Hydroxy[6a-acetoxy,23-ethoxy, 16fl, 23(R) epoxy-24,25,26,27-tetranor]9fl,19-cyclolanostane 25:185
20S-Hydroxy- 1,2-dehydropseudoaspidospermidine 5:126;9:195 4-Hydroxy- 1,2-dithiolane 7:193,194 5-Hydroxy- 1,4-naphthoquinone 14:49 2-Hydroxy- 1,4-naphthoquione 26:804 1[3-Hydroxy-10,14-dehydro- 1,10Hparthenolide 27:566 6-Hydroxy- 10-formamido- 15-isothiocyano-kalihinene 25:856 11-Hydroxy- 10-methoxynoracronycine 13:348,349 from Citrus decumna 13:348,349 (E)-trans- 1-Hydroxy- 10-vinyl-2cyclodecene 8:196 synthesis of 8:196 (Z)-trans- 1-Hydroxy- 10-vinyl-2cyclodecene 8:196 synthesis of 8:196 6et-Hydroxy- 11,13-dihydro-5,7ctH,8, 11~H-eudesm-4(15)-en-8,12-olide 27:552 1-Hydroxy- 11-methoxycanthin-6-one 7:389,390 12-Hydroxy- 11-methoxydiaboline 9:189 10-Hydroxy- 11-methoxydracaenone 5:17-20 12-Hydroxy- 11-methoxyhenningsamine 9:27 12-Hydroxy- 11-methoxy-N-acetyl-norC-fluorocurarimine 26:1052,1053 12-Hydroxy- 11-methoxy-nor-Cflourocurarine 26:1052 19-Hydroxy- 11-methoxytabersonine 2:375 10-Hydroxy- 11-methoxytabersonine 5:128 6-Hydroxy-12-tridecene 9:241,243 3[3-Hydroxy-13,14,15,16-tetranorlabda7,9( 11)-dien-( 19,613),(12,17)-diolide 28:508 synthesis of 28:508 Ent- 16-Hydroxy- 13[R]-pimar-8( 14)ene-3,15-dione 9:283-287,290 Ent- 13[S]-Hydroxy- 14-oxo-3,4-secoatis-16-en-3,4-olide 9:268,269,276 14-Hydroxy- 15-isovaleroyloxy-9-oxomelampolide 29:89
397 activity in NFkB assay system 29:89 Hydroxy- 15[3-aristoline 9:172 16 (S)-Hydroxy-16,17-dihydroapparicine 6:505,506 16S-Hydroxy- 16,22-dihydroapparicine 5:124 16S-Hydroxy- 16,22-dihydroapparicine 9:171,172 3fl,7a 22-Hydroxy- 16,23-epoxy-24,25, 26,27-tetranor-9fl, 19-cyclolanostane 25:184 3R/S-Hydroxy- 16-decarbomethoxyconodurine 5:125 10-Hydroxy-16-epi-affinine 5:124 19(R)-Hydroxy- 18,19-dihydrokoumine 15:476,477 19(S)-Hydroxy- 18,19-dihydrokoumine 15:476 from Gelsemium elegans 15:476 X-ray analysis of 15:477 18-Hydroxy- 19(Z)- anhydrovobasinediol 15:500 Hydroxy- 1-arylthiobutenes 4:477,478 cycloaddition with 4:477,478 1c~-Hydroxy-1-desoxoarglamine 27:549 1c~-Hydroxy-1-desoxochrysanolide 27:559 1[3-Hydroxy- 1-desoxochrysanolide 27:559 lct-Hydroxy- 1-desoxo-tamirin 27:568 1~-Hydroxy- 1-desoxo-tamirin 27:568 11-Hydroxy- 1-methoxycanthin-6-one 7:389,390 1-Hydroxy- 1-methylindolizidines 12:282 4-Hydroxy- 1-oxo- 1,2,3,4-tetrahydronaphthalene 11:118 1-Hydroxy- 1-phenylindolizidines 12:282 E-(3-Hydroxy- 1-propenyl)[3-Dglucopyranosetetraacetate 10:422 (6S*,7S*, 10R*)-3-Hydroxy-2,10,10trimethyl-7,10-epoxy-dodeca- 1,11dien-5-one 27:594 13-Hydroxy-2,15-diacetoxy- 11-epiapotrichothec-9-ene 9:210
23-Hydroxy-2,16-dehydroretuline 1:38,39;9:186 Cis (3 S, 5R)-2-Hydroxy-2,2,6-trimethyltetrahydropyran 25:143 (4R,6R)-4-H ydro xy-2,2,6-trime thylcyclohexanone 6:143,144,158 synthesis of 6:158 3-Hydroxy-2,2,6-trimethyltetrahydropyran 25:144 6-Hydroxy-2,2-dimethyl chromene 10:248 (4S)-4-Hydroxy-2,6,6-trimethyl-2cyclohexen-l-one 6:159 synthesis of 6:159 7-Hydroxy-2 '-metho xy-4 '5 '-methylenedioxyisoflavan 256 27:499 structure 27:473 of 25-Hydroxy-20,24-epoxy 27:473 3 [3-Hydroxy-20 -methoxy-30-norolean12-en-28-oic acid 7:139,140 21 ct-Hydroxy-20,22-dioxo-30(20~21) abeo-21-desoxotingenone 30:670 13C-NMR of 30:670 HMBC of 30:670 molecular formula of 30:670 MS of 30:670 NOE of 30:670 (15R)- 15'-Hydroxy-20'-deoxyvinblastine 14:814,815 acetyl derivative of 14:814,815 from 20'deoxy- 15 '-oxovinblastine 14:814,815
19R-Hydroxy-20-epi-ibophyllidine 5:127
19S-Hydroxy-20-epi-ibophyllidine 5:127;9:190,192
18-Hydroxy-20-epi-ibophyllidine 9:190 19R-Hydroxy-20-epi-ibophyllidine 9:190
(+)-19-Hydroxy-20-epi-pandoline 5:124 19-Hydroxy-20-epipandoline 9:190
20-Hydroxy-22-oxo-20-epi-tingenone 30:670 13C-NMR of 30:670 HMBC of 30:670 molecular formula of 30:670 MS of 30:670 NOE of 30:670
398
20-Hydroxy-22-oxotingenone 30:670 13C-NMR of 30:670 HMBC of 30:670 molecular formula of 30:670 MS of 30:670 NOE of 30:670 25-Hydroxy-24-epicastasterone 18:529 26-Hydroxy-24-epicastasterone 18:529 1cx-Hydroxy-25-oxa-25-phosphavitamin D3 9:520 4-Hydroxy-2-cyclopentenone acetal from meso-3,4-epoxycyclopentanone 14:510 8-Hydroxy-2'-deoxyguanosine 26:253 (+)-1-Hydroxy-2-epi-pinoresinol 5:538 (3S)-3-Hydroxy-2-ethyl-butyronitriles 13:59 3-Hydroxy-2-hydroxymethyl pyrrolidine 14:570 hydrochloride 14:570 from pyrrolidine derivative 14:570 3-Hydroxy-2-hydroxymethyl-6substituted piperidines 12:474 1-Hydroxy-2-hydroxymethylanthraquinone 26:660 9-Hydroxy-2-methyl ellipticine 22:9 1-Hydroxy-2-methyl-anthraquinone 26:660 7-Hydroxy-2-methyl-anthraquinone 26:676 Hydroxy-2-methylantraquinone 26:676 12-Hydroxy-2-methyldodecanal 26:70 wittig reaction of 26:70 (R)-3-Hydroxy-2-methylpropionate 6:292,293 (S)-5-Hydroxy-2-penten-4-olide 14:273,274 from levoglucosenone 14:273, 274 4-Hydroxy-2-pyridone chromophore 21:215 2-Hydroxy-3-(2-methoxyphenyl) propenoic acids 30:222 cyclisation of 30:222 7-Hydroxy-3-(3-hydroxy-4methoxybenzyl) chromane 5:20-22 13-Hydroxy-3,11-epoxy APO 13:522
(20R)-Hydroxy-3,24-diepibrassinolide 18:531 25-Hydroxy-3,24-diepibrassinolide 18:532 (20R)-Hydroxy-3,24-diepicastasteron 18:531,539,542 8-Hydroxy-3,4-dihydroisocoumarin 15:384 7-Hydroxy-3,4-epoxy-laurane (laurol) 9:193,194,199 6-Hydroxy-3,5,9,11-tetraoxodo-decanedioate 11:118 from c~-hydroxyglutarate 11:118 (E)-6-H ydroxy-3,7-dimethyl-2,7ocatdienyl xanthoangelol B 30:76 1-Hydroxy-3,7-dimethyl- 6- octen- 2- one 25:133 (+)-(4'-Hydroxy-3'-methoxycinnamoyl)-epil-upinine 27:268 3-Hydroxy-30-norolean- 12,19-dien-28oic acid 7:139,140 3 [3-Hydroxy-30-nor-olean- 12,20(29)dien-28-oic-acid 9:51 ent-8c~-Hydroxy-labda-13 (16), 14-diene 25:273,274 19'S-Hydroxy-3-epi-ervafolidine 5:129 2-Hydroxy-3-methoxy strychnine 26:1030,1052 2213-Hydroxy-3-methoxy-6-oxotingenol 30:680,681 ~H-NMR spectrum of 30:680 molecular formula of 30:680,681 ROESY experiment of 30:681 structure of 30:681 3,4-bis(4-Hydroxy-3-methoxy-benzyl) tetrahydrofuran 26:255 1-Hydroxy-3-methoxyxanthone 25:467 2-Hydroxy-3-methoxyxanthone 5:759 (-)-8-Hydroxy-3-methyl-3,4-dihydroisocumarin 15:383 3-Hydroxy-3-methylglutaryl CoA 25:130 3-Hydroxy-3-methylglutarate 21:634 S-3-Hydroxy-3-methylglutaryl 27:383 3-Hydroxy-3-methyl-glutaryl coenzyme A reductase 11:335
399 3-Hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase 24:351-398 fungal metabolism of 24:361,362 in metabolism 24:359-361 regulation of 24:361,362 3-Hydroxy-3-methylglutarylcoenzyme 27:386 22[~-Hydroxy-3-oxo- 12-ursen-30-oic acid 30:654 ~3C NMR spectrum of 30:654 stereochemistry of 30:654 28-Hydroxy-3-oxo- 12-ursen-30-oic acid 30:654 ~3C NMR spectrum of 30:654 2D NMR spectral analysis of 30:654 7-Hydroxy-3-oxoindolizidine 12:287, 288 synthesis of 12:287,288 15'-Hydroxy-3'-oxoleurosidine 14:812, 813 from anhydrovinblastine N-oxide 14:812,813 28-Hydroxy-3-oxo-olean- 12-en-29-oic acid 30:649 2D NMR spectroscopic of 30:649 17-Hydroxy-3-oxotabersonine 4:58,59 reaction with nitrogen nucleophiles 4:58,59 reaction with sulfur nucleophiles 4:58,59
N-2-Hydroxy-3-trans-octadecenoyl- 1-
O-D-glucosyl-9-methyl-cis-4,8sphingadienine 18:807 8-Hydroxy-3-undecyl-3,4dihydroisocoumarin 15:386 2-Hydroxy-4-(O-prenyl)-benzaldehyde 21:742 3 [3-Hydroxy-4,4,14-trimethylpregna9(11), 16-diene-20-one 7:279 Ent- 13 [S]-Hydroxy-4,5-oxy-4,5-oxy4,5-seco-atis- 16-ene-3,14-dione 9:268,269,276 1'-Hydroxy-4'-oxo-c~-ionone 27:330 6-Hydroxy-4a-aryl-cis-decahydroisoquinolines 12:458,459
synthesis of 12:458,459 6-Hydroxy-4a-aryl-transdecahydroisoquinolines 12:457 3-Hydroxy-4-alkoxy substitution 15:30 6'-Hydroxy-4'-methoxyavarone 15:301 2-Hydroxy-4-methyl acetophenone 23:165 (+)-5-Hydroxy-4-oxonorvaline(+)HON 13:512,513 5-Hydroxy-4-oxyindolizidines 12:284 3-Hydroxy-4-pentenyl amines 14:568 stereoselective cyclization of 14:568 to pyrrolidines 14:568 6-Hydroxy-4ot-phenyldecahydro 12:457 from 6-hydroxy-4a-aryl-transdecahydroisoquinoline 12:457 11-Hydroxy-5,14-diacetoxy-9,10dehydrofarnesol acetate 27:586 6c~-Hydroxy-5,7~H,8[3H-eudesm-4( 15)en-8,12-olide 27:552 6'-Hydroxy-5'-acetyl-avarol 15:301 6-Hydroxy-5-methylmellein 9:288,289 5-Hydroxy-5-vinyl-2-cyclopenten- 1ones 14:625 2-Hydroxy-6-(2-oxoheptyl) benzoic acid 9:328 (E)- 10-Hydroxy-6,10-dimethyl-5undecen-2-one 25:168 5-Hydroxy-6,7,3',4',5'-pentamethoxyflavone 5:756,757 5-Hydroxy-6,7,4-trimethoxyflavone 5:653 5-H ydroxy-6,7,8,4'-tetramethoxyflavone 5:653 5-H ydroxy-6,7,8-trimethoxyflavo ne 5:652 5-Hydroxy-6,7-dimethoxyflavone 5:652
12-Hydroxy-6,7-seco-abieta-8,11,13-
trien-6,7-dial 29:99 activity in EBV assay system 29:99 2-Hydroxy-6-[(Z)-heptadec-8-enyl] benzoic acid 9:316 4[3-Hydroxy-6-deoxy-6-deoxycelorbicol 18:743 (+)- 1-Hydroxy-6-epi-pinoresinol 5:538, 540,541
400
7-Hydroxy-6-methoxy- 1-methylisoquinoline 30:564,589 activity in human cancer cell line 30:589 cytotoxic effect of 30:589 7-Hydroxy-6-methoxycoumarin 9:288, 289 2-Hydroxy-6-methylbenzoic acid 9:341, 347,350 7-Hydroxy-6-methylhept-5-en-2-one 25:138 7-Hydroxy-6-methylhept-5-ene-2-one- 1ol 25:136 7-Hydroxy-6-methylheptan-2-one 25:138 5-Hydroxy-6-oxo-coronaridine 5:127 23-nor-22f3-Hydroxy-6-oxotingenol 30:680 13C-NMR of 30:680 DEPT of 30:680 1H-NMR spectrum of 30:680 HMBC experiment of 30:680 molecular formula of 30:680 2-Hydroxy-6-pentadecylbenzoic acid (15:0-anacardic acid) 9:336,345, 346,372 2-Hydroxy-6-tetradecylbenzoic acid 9:317 2-Hydroxy-6-undecylbenzoic acid (anagigantic acid) 9:316 1J3-Hydroxy-6c~-angeloyl-oxyeudesm4(15), 1l(13)-dien-8,12-olide 27:552 1~-Hydroxy-6c~-angeloyl-oxygermacra4(5), 10(14), 1l(13)-trien-8,12-olide 27:561 (2 S,6S)-2 ~-Hydroxy-613-acetoxynortropane 21:751 2213-Hydroxy- 7,8- dihydro- 6-oxotinge no 1 30:681 IH-NMR spectrum of 30:681 molecular formula of 30:681 5-Hydroxy-7,8-dimethoxyflavone 5:640 4-Hydroxy-7[ I -hydroxy-7-[ 1-hydroxy2-methylamino)ethyl]-l,3-benzothiazole-2(3H)-one 25:896
( 1R*,3S*,4R*,7 S*, 8S, 12R*, 13R*)- 12Hydroxy-7-isothiocyanatoamphilecta-1 l(20),14-dlene 25:853 1-Hydroxy-7-methoxyxanthone 5:759 7-Hydroxy-7-methyl-5-oxoindolizidine 12:289 configuration of 12:289 synthesis of 12:289 7-Hydroxy-7-phenylindolizidines 12:286 8a-Hydroxy-7ct(H)-eremophila- 1,11diene-9-one 15:242 ent- 16-Hydroxy- 13-epi-manoyl oxide 25:250 ent- 19-Hydroxy- 13-epi-manoyl oxide 25:253 ent-3a-Hydroxy- 13-epi-manoyl oxide 25:250 ent-3fl-Hydroxy- 13-epi-manoyl oxide 25:253,254,267,263 Hydroxy-8-methoxyflavonoid 5:64062-Hydroxy-8-p-mehthen-7-oic acid 25:149 9c~-Hydroxy-813-methacryloyloxy- 14oxo-acanthopsermolide-4a,5 [3epoxide 29:89 activity in NFkB assay system 29:89 ent-4ot-Hydroxy- 19-nor-Beyer- 15-ene 30:714 structure of 30:714 7-Hydroxy-9(11)-secogorgosterol 21:312 13-Hydroxy-9,11-octadecadienoic acid 21:197 5-Hydroxy-9-acetoxynerolidol 27:586 8~-Hydroxy-9c~-methacryloyloxy- 14oxo-acanthospermolide 29:89 activity in NFkB assay system 29:89 from Milleria quiqueflora 29:89 Ent- 17-Hydroxyabieta- 8(14), 13( 15)dien-16-al 9:83,284 Ent- 11ot-Hydroxyabieta-8(14),3( 15)dien- 16,12-olide 9:283,284-290 7'-Hydroxyabscisic acid 27:348 8'-Hydroxyabscisic acid 27:345,350 isomerization rates of 27:350
401 ot-Hydroxyacetophenone 21:147 p-Hydroxyacetophenone 21:741;30:731 structure of 30:731 8ot-Hydroxyachillin 27:574 Hydroxyachillin 29:89 activity in TPA assay system 29:89 activity in PKC assay system 29:89 activity in CRG assay system 29:89 1-Hydroxyacridin-9-one (N-methylnoracridin)-9-one 13:348,362,363 11-Hydroxyacronycine 13:357,358,366, 367 [3-Hydroxyacteoside 5:506,509,511, 513,514 2-Hydroxyaklavinone 11:120 12-Hydroxyakuammicine 5:123;9:193 4[3-Hydroxy-alatol 18:747 o~-Hydroxyaldehyde derivatives 6:316,317 synthesis of 6:316,317 oc-Hydroxyaldehydes 6:336,337 synthesis of 6:336,337 [3-Hydroxyalkyl selenides 8:4 from cyclohexanone 2,2,6,6tetramethyl 8:4 from deoxybenzoine 8:4 2,2,6-trimethyl cyclohexanone 8:4 1-(c~-Hydroxyalkyl) isoquinolines 12:449 2-(o~-Hydroxyalkyl) piperidines 12:453 diastereoselective synthesis of 12:453 synthesis of 12:453-456 2-(c~-Hydroxyalkyl) pyrrolidines 12:473 synthesis of 12:473 1-(ot-Hydroxyalkyl)- 1,2,3,4-tetrahydroisoquinolines 12:450 chiral synthesis of 12:450 c~-(ot'-Hydroxyalkyl)-N- heterocycles 12:447 5-Hydroxyalkylbutan-4-olides 3:160-161 synthesis of 3:160-161
(+)- 16-Hydroxy-allo-ibogamine 6:503 biogenesis of 6:503 Hydroxyalpinolide 23:814 6Hydroxyamide 8:231,234 12ot-Hydroxyamorphigenin 27:574 8-Hydroxyanamycins B,O,S,W 9:443 15-Hydroxy-angustilobien A 9:171 8a-Hydroxyanhydroverlotorin 27:572 313-Hydroxyanhydroverlotorin 27:573 18-Hydroxyanhydrovobasinediol 15:503 9-Hydroxyanthracene 11:119 from homophthalate 11:119 synthesis of 11:119 Hydroxyanthracenones 22:580,582 3-Hydroxyanthranilic acid 26:965,966, 978,1015 5-Hydroxyanthranilic acid 26:971 2-Hydroxyanthraquinone 26:659 Hydroxyanthraquinones 22:556,564 (+)-2 ~-Hydroxyaphylline 27:273 4-Hydroxyaporphines 16:510 synthesis of 16:510 1[3-Hydroxyarbusculin A 27:549 8c~-Hydroxyarbusculin A 27:549 2~-Hydroxyartemorin 7:211 from Artemisia hispanica 7:211 2-Hydroxyarylpropenoic acids 30:221 4'-and 5'-Hydroxyasperentin 15:386 Ent- 18-Hydroxyatis- 16-ene-3,14-dione 9:268,269,279 Ent- 13[S]-Hydroxyatis- 16-ene-3,14dione 9:268-276,9:279,280,286, 290 6'-Hydroxyavarol 15:301 3'-Hydroxyavarone 15:301 1-13-Hydroxybaccatin I 11:5 5-Hydroxy-benzoquinone-l-(2'-hydroxy6'-carboxyanil)-4-imide 26:1003 m-Hydroxybenzaldehyde 10:121,125 Hydroxybenzoate 25:660 Hydroxybenzoic acid 25:655,660,661, 922,923,947 Hydroxybenzoic acid derivatives 28:259 benzoic acid as 28:259 gallic acid as 28:259 4-hydroxybenzoic acid as 28:259
402 isovanillic acid as 28:259 protocatechuic acid as 28:259 salicylic acid as 28:259 syringic acid as 28:259 vanillic acid as 28:259 p-Hydroxybenzoic acids 23:750 glucosides of 23:750 ortho-Hydroxybenzyl 21:162 para-Hydroxybenzyl 21:162 p-Hydroxybenzyl isothiocyanate 26:1076 S-(4-Hydroxybenzyl) glutathione 25:820 Hydroxybenzyloxycarbamoyl 21:168 3fl-Hydroxybiformene 25:249 (-)-3-exo-Hydroxyborneol 4:647,648 (-)-5-endo-Hydroxybomeol 4:647,648 (-)-6-exo-Hydroxyborneol 4:647,648 (+)-5-exo-Hydroxyborneol 4:647,648 (+)-5-endo-Hydroxyborneol 4:648 (3R)-3-Hydroxybutanethioate 13:500 boron enolate of 13:500 (R)-3-Hydroxybutanoic acid acetals 1:610 diasteroselective allylation of 1:610 [3-Hydroxybutanoic acid ester 10:410 3-(4-Hydroxybutyl)-5-propylindolizidine 11:253 absolute stereochemistry of 11:253 biological activity of 11:253 synthesis of 11:253-256 (S)-(-)-3-Hydroxybutylate 23:214 (R)-3-Hydroxybutyrate 12:154 (S)-3-Hydroxybutyrate 6:300,301 as chiral precursor 6:300,301 3-Hydroxybutyrates 4:439 anti-products formation 4:439 in thienamycin synthesis 4:431 [3-1actam formation 4:446 lithio dianions of 4:441 3-Hydroxybutyric acid 4:431,438,440, 465,471,479,480 acid chlorides of 4:471 in thienamicin synthesis of 4:438-440 6-Hydroxycalyxin F 26:902
22a-Hydroxycampesterol 25:415,418, 420 conversion of 25:418 endo-3-Hydroxycamphor 4:660 exo-3-Hydroxycamphor 4:660 11-Hydroxycanthin-6-one 7:389,390 11-bromobenzoate of 7:389,390 10-Hydroxycanthine-6-one 7:393 (z-Hydroxycarboxylic acid 8:140 derivatives of 8:140 6a-Hydroxycatasterone 25:424 (15R)-15'-Hydroxycatharinine 14:820, 821 biosynthesis of 14:820,821 from anhydrovinblastine 14:813,814 from leurosine 14:813,814 25-Hydroxy-celapanol 18:744 4f3-Hydroxy-celapanol 18:744 4[3-Hydroxy-celorbicol 18:743 Hydroxychavicol 23:801 Hydroxychloroquine 22:148 25-Hydroxycholesterol 24:352 cytotoxicity effect of 24:352 2-Hydroxychrysophanol 9:400,401 Hydroxycinnamates 25:656 Hydroxycinnamic acid 23:744,771; 25:652,657,666,919,920 derivatives of 23:744 Hydroxycinnamic acid derivatives 23:771;28:260
(-)-(trans-4'-Hydrox y-c innamoyl ) lupinine 15:521
from Luplnus luteus 15:521 25-Hydroxycolecalciferol 9:521 1f3-Hydroxycolecalciferol (alfacalcidol) 9:521 Hydroxy-colorenone 21:281 5-Hydroxyconiferaldehyde 5:470 3-R/S-Hydroxyconoduramine 5:125 3-R/S-Hydroxyconopharyngine 5:128 19R-Hydroxyconopharyngine 5:128 19S-Hydroxyconopharyngine 5:128 3R-Hydroxyconopharyngine 9:174 3-R-Hydroxyconopharynginehydroxyindolenine 5:.128 3S-Hydroxyconopharynginehydroxyindolenine 9:195
403 19-Hydroxycoronaridine 5:126 3-R/S-Hydroxycoronaridine 5:126 10-Hydroxycoronaridine 5:127;9:174 11-Hydroxycoronaridine 5:127;9:174, 176,177 3R-Hydroxycoronaridine 9:171 10-Hydroxycorynanthediol 14:709,710 synthesis of 14:709,710 7-Hydroxycostunolide 29:89 activity in NFkB assay system 29:89 7-Hydroxycoumarin 23:338 3-Hydroxycoumarin 30:220,221,225 antioxidant properties of 30:225 structure of 30:220 7-Hydroxycoumarin (umbelliferone) 9:114 Hydroxycoumarin esculin 26:314 Hydroxycoumarins 26:330 antimicrobial activity of 26:330 (+)-4-Hydroxycrebanine 16:510 synthesis of 16:510 12-Hydroxyculmorins 13:536 15-Hydroxyculmorins 13:536 5-Hydroxyculmorins 13:536 from Fusarium culmorum 13:536 15-Hydroxyculmorons 13:536 313-Hydroxycycloar-25-en-24-one 9:288,289 21-Hydroxycyclolochnerine 13:389 R,S-4-Hydroxycyclopentenones 6:315 absolute configuration 6:315 asymmetric synthesis 6:315 from D,L-tataric acid 6:315 21 a-Hydroxy-D :A-friedo-olean-3-one 7:147,148 20(S)-Hydroxydamaran-3 [3-yl acetate 2:91,92 oxidation with m-CPBA 2:91,92 20(S)-Hydroxydammaran-3-oen 2:94 Hydroxydammarenone-I 23:546 Hydroxydavanone 27:592 10-Hydroxydeacetylakuammiline 9:195 4-Hydroxydecanoic acid 13:308,315 10-Hydroxydecanoic acid 26:65 methanolysis of 26:65
12-Hydroxydehydroabietic acid 29:99 activity in EBV assay system 29:99 4S-Hydroxy-dendrolasin 15:233 4-Hydroxyderricin 30:74,76 effect on catecholamine-induced vasoconstriction 30:74 inhibitory action of 30:76 inhibitory mechanism of 30:74 1~-Hydroxy-desacetylirinol-4c~,5 [3epoxide 27:565 Hydroxydictyodial 5:370 20-Hydroxydihydrocatharanthinic acid lactone 14:815,816 6-Hydroxydihydrochelerythrine 14:773-775 (+)- 16-Hydroxydihydrocleavamine 14:850-853 synthesis of 14:850-853 6-Hydroxydihydrocleavamine 4:291 coupling with vindoline 4:29 16-Hydroxydihydrocleavamine 5:183,184 synthesis of 5:183,184 Hydroxydihydroeremophilone 15:239,241 A3~4)-15-Hydroxydihydroflabellin 27:579 19(S)-Hydroxydihydrogelsemine 15:479 from Gelsemium elegans 15:479 from Gelsemium rankinii 15:479 19(R)-Hydroxydihydrogelsemine 15:481 from Gelsemium rankinii 15:481 from Gelsemium sempervirens 15:481 19(S)-Hydroxydihydrogelsevirine 15:479 19(R)-Hydroxydihydrogelsevirine 15:479 from Gelsemium elegans 15:479 19(S)-Hydroxydihydrokoumine 15:475 (-)-( 10R)-Hydroxydihydroquinine 14:464,465 synthesis of 14:464,465 20-Hydroxydihydrorankinidine 15:472, 473
404 X-ray analysis of 15:472,473 6-Hydroxydihydrosanguinarine 27:173 structure of 27:173 Ent-7 c~-Hydroxydiplophyllolide 2:278,279 Hydroxy-directed epoxidation 12:300 of trifluoracetate salt 12:300 2-Hydroxydiscorhabdin D 25:823 12-Hydroxy-E-T-bisabolene 23:166 20-Hydroxyecdysone 22:376;25:413 Hydroxyeicosatetraenoic acids 22:112 Hydroxyeicosatrienoic acids 26:759 10-Hydroxyellipticine 6:507 anticancer activity of 6:507 from Strychnos dinklagei 6:509 spectral data of 6:518 17-Hydroxyellipticine 6:513-515 from Strychnos dinklagei 6:515 spectral data of 6:515,519 18-Hydroxyellipticine 6:515,516,519 m-Hydroxy-E-nerolidol 25:162 endo-2-Hydroxyepicamphor 4:660 Hydroxy-epoxides (hepoxilins) 9:577 8ot-Hydroxyeremophilone 15:242 (22 S-24R)-22-Hydroxyergos-4-en-3-one 418 19'-Hydroxyervafolen 5:129 8(x-Hydroxyestafiafin 27:578 1,3,5-tris-(2-Hydroxyethyl) cyanuric acid 12:411,415 2-oxazolidinone from 12:411, 415 2-(l'-Hydroxyethyl) propenoates 4:479 nuceophilic conjugate addition to 4:479 24-(13-Hydroxyethyl)-and 24-(carboxymethyl) steroids 15:79-81 absolute configuration of 15:79-81 3-([3-Hydroxyethyl)-coronaridine 9:171 (S)- 1-(1 '-Hydroxyethyl)-[3-carboline 18:726 3S-3D-Hydroxyethylcoronaridine 5:126 5-Hydroxyethylmellein 9:288,289 (N-2-Hydroxyethylpiperazine-N'-2ethane-sulfonic acid) buffer 15:443 Hydroxyethylrutosides 22:437;26:756 6a-Hydroxyeurycomalactone 23:301
12-Hydroxyfarnesol 25:165,166 4-Hydroxyfarnesolacetate 27:586 5-Hydroxy-ferulic acid 5:469,470 Hydroxyferuloyl-CoA 5:470 7-Hydroxyflavanone 4:378,380 3-Hydroxyflavanones 7:192 3-Hydroxyflavone 22:327;26:757, 761-764,768,769 5-Hydroxyflavone 5:630;22:327;25:543 2'-Hydroxyflavone 5:12-14 2'-Hydroxyflavonoids 5:640 2'-Hydroxyflavonol-3-methyl ethers 5:640 Hydroxyframoside A&B 26:325,326, 333 2 lot-Hydroxyfriedela-3-one 5:744,746 7-Hydroxyfrullanolide 9:143-145 from Spharanthus indicus 9:143 2-Hydroxyfuran-2-one 30:222,224 as ascorbic acid analogue 30:224 decarboxylation of 30:222 lactonisation of 30:222 18-Hydroxygardnutine 15:502 10-Hydroxygeissoschizol 5:126 10-Hydroxygeissoschizol diacetate 9:174 14-Hydroxygelsedine 15:482 from Gelsemium elegans 15:482 from Gelsemium sempervirens 15:482 14[3-Hydroxygelsedine 9:196 14-Hydroxygelsemicine 15:481 from Gelsemium sempervirens 15:482 14-Hydroxygelsemicine 9:196,197; 15:481,482 from Gelsemium elegans 15:482 8-Hydroxygeraniol 25:140 11-Hydroxygeranylacetone 25:165,168 13-Hydroxygibberellins 6:181 preparation of 6:181 12-Hydroxygibberellins 6:190-194 preparation of 6:190-194 3-Hydroxyglabrol 28:228 biological activity of 28:228 (+)-7 ct-Hydroxyglaucines 16:504 (+)-7 [3-Hydroxyglaucines 16:504
405 (2R,3R)-3-Hydroxyglutamic acid 12:477 synthesis of 12:477 13-Hydroxyglutarate 11:127 naphthalenediol from 11:127 3-Hydroxyglycals 3:228 3a-Hydroxy-gomeric acid 25:249 3-Hydroxyguaiazulene 14:321,324 413-Hydroxyhernandulcin 15:15; 27:13,21 structure of 27:21 (+)-N-Hydroxyhernangerine 30:564,589 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:589 (R)-2-Hydroxyhexadecanoic acid 1:681 8-Hydroxyhexadecanoic acid 1:683,684 synthesis of 1:683,684 6-Hydroxyhexadecanoic acid 21:188 Hydroxyhexadecanoic acid (tricolorin A) 25:543 2 '-Hydroxyhexadecanoyl- 1-O-[3-Dgluc op yrano syl-9-methyl-4,8-Derytho-sphingadienine 18:814 10-Hydroxyheyneanine 5:127; 9:174-176 11-Hydroxyheyneanine 5:127 (+)-20-Hydroxyhobartine 11:323 (+)-aristocarbinol from 11:323 (+)-aristolasene from 11:323 aristolarine from 11:323 sorelline from 11:323 3[3-Hydroxyholosta-7,25-dien- 16-one 7:275,279 3 [3-Hydroxyholosta-9(11),25-dien- 16one 7:277,278 15-Hydroxyhumantenine 15:472,473 7[3-Hydroxyhyoscyamine 17:397-399 6[3-Hydroxyhyoscyamine 17:398-399 Hydroxyhyperforin 30:613 structure of 30:613 14-Hydroxyhypocretenolide 29:90 activity in NFkB assay system 29:90 activity in CRO assay system 29:90
14-Hydroxyhypocretenolide- [3-Dglucoside-4',4"-hydroxy-hypocretenoate 29:90 activity in CRO assay system 29:90 activity in iNOS assay system 29:90 activity in NFkB assay system 29:90 12-Hydroxyibogaine 21:72,84 19R-19-Hydroxyibogamine 5:126 19R-Hydroxyibogamine pseudoindoxyl 5:123 19R-Hydroxyibophyllidine 5:127 19-Hydroxyibophyllidine 9:190,192 5-Hydroxyindole acetic acid 22:670 1-Hydroxyindolizidine 12:278,279 diastereomers of 12:278,279 (-)-( 1R, 8aS)- 1-Hydroxyindolizidine 12:278,281 enantioselective synthesis of 12:281 from Astragalus oxyphysus 12:278 from Rhizoctonia leguminicola 12:278 (+)-cis-l-Hydroxyindolizidine 12:279, 280 synthesis of 12:279,280 (+)-( 1S,8aS)- 1-Hydroxyindolizidine 12:281 enantioselective synthesis of 12:281 from Rhizoctonia leguminicola 12:278 (+)-cis-2-Hydroxyindolizidine 12:284 (+)-trans-2-Hydroxyindolizidine 12:284 2-Hydroxyindolizidine 12:284 relative configuration of 12:284 synthesis of 12:283,284 6-Hydroxyindolizidine 12:285,286 synthesis of 12:285,286 7-Hydroxyindolizidine 12:285,286 antitremorine action of 12:286 synthesis of 12:286-289 cis-8-Hydroxyindolizidine 12:293 8a-Hydroxyindolizidine 12:300-303
406 1-Hydroxyindolizidine-6-carboxylic aid 12:283
17-Hydroxy-ingeno120-hexadecanoate
29:102 activity in mam-2 bioassay system 29:102 6ot-Hydroxyiridomyremcin 7:476 [3-Hydroxyisobutyric acid 13:87 (S)-[3-Hydroxyisobutyric acid 18:172 28-Hydroxyisoiguesterine 30:667 molecular formula of 30:667 Hydroxyisoindolone 13:114 3-Hydroxyisoleucine 15:347 Hydroxyisopiperitenone 25:151 Cis (3 S, 5R)-2-(2-Hydroxyisopropyl)-5methyltetrahydrofuran 25:143 16-Hydroxyisoretulinal 1:36;9:186 12-Hydroxyisoretulinal 1:36 18-Hydroxyisoretuline 1:38,39 c~-Hydroxy-isovaleric acid 13:533 3-R/S-Hydroxyisovoacangine 5:127 [3-Hydroxyketone 14:458,459;17:365; 30:23 1,3-anti reduction of 30:23 synthesis of 17:365;14:458,459 ot-Hydroxyketone 6:337;8:224,225; 14:458,459 synthesis of 6:337;8:224,225; 14:458,459 3-Hydroxykynurenine 26:965-967,988, 997,999 Hydroxyl inversion 1:204,205 13-Hydroxyl ofbaccatin III 12:218 Hydroxyl removal 1:454,456 3fl-Hydroxyl, A5'6 steroids 25:419 6-Hydroxy-l,2,3,4-tetrahydropyrrole (1,2-a) pyrimidinum skeleton 25:829 12S-Hydroxylabda- 8(17), 13(16), 14trien- 19-oic acid 29:101 activity in EBV bioassay system 29:101 ent- 15-Hydroxy-labda-8 (17), 13E-dien3-one 29:102 activity in EBV bioassay system 29:102 lc~-Hydroxylase 9:515 inhibitors of 9:515 25-Hydroxylase 9:520
Hydroxylated germacrene C2 23:160 Hydroxylated germacrene C5 23:160 Hydroxylated indolizidines 12:275-363 trans-Hydroxylation 1:413,414 of olefin 1:413,414 ofolefinic double bond 16:16 with H202 1:260 with WO3 1:260 cis-Hydroxylation 1:413,415;4:45,145, 204,205,344 lincosamine derivative from 4:145 of acrylates 4:45 of E-allylic alcohol 4:204 of Z-allylic alcohol 4:205 stereoselective 1:413,415,4:511 stereospecific 4:503,504 Whiteside's procedure 1:668 with Ba(CLO3)2 1:260 with CuC12/Cu/O2 5:827 with osmium tetroxide 4:508,509 with OSO4 1:260 with OsO4-chiral base 4:344 12~-Hydroxylation 13:663 t0-Hydroxylation 25:136,138,162,163, 166,168 c~-Hydroxylation 4:331,333;13:43; 27:199 of cyclic hydroxamic acid 27:199 Hydroxylation 5:827;24:70-72,76,178, 179;27:346,749,754;28:335 by cytochrome P450 27:346 by stereospecific double bond 11:464 of (1 'R)-(-)-Abscisic acid 27:348 of arenes 27:749 of indoles 27:754 of MFA 28:335 of paraherquamide A 28:331,367 o-Hydroxylation 5:826 of 2-alkylbenzoic acids 5:826 C-3Hydroxylation 7:359-361 1 l[3-Hydroxylation 9:417 Hydroxylation of tomatidine 25:318 15c~-Hydroxyleurosidine 14:812,813 from anhydrovinblastine N oxide 14:812,813
407 (15'R)-15-Hydroxyleurosidine 14:814, 815 (15'S)- 15'-hydroxyleurosidine from 14:814,815 Moffatt oxidation of 14:814,815 (2S,3R)-~-Hydroxy-L-glutamic acid 12:431,432 synthesis of 12:431,432 10-Hydroxyligstroside 26:334,343 8-Hydroxylinalool 25:136,140,142 8R-Hydroxylinoleic acid 21:187 9Z,12Z-8-Hydroxylinoleic acid 21:187 18-Hydroxylochnerine 13:386 23-Hydroxylongispinogenin 18:650,656 from Corchorus acutangulus 18:650 4-Hydroxy-L-proline 13:445 trans-4-Hydroxy-L-proline 13:485 (-)-6c~-Hydroxylupanine 15:524 (+)- 12ct-Hydroxylupanine 15:524 from Lygos raetam 15:524 313-Hydroxylupanine 21:80 6-Hydroxyluteolin 5:654,665 6-Hydroxyluteolin-6,7-disulphate 5:655 6-Hydroxyluteolin-7-O-(6"-caffeoyl)sophoroside 5:654 6-Hydroxyluteolin-7-sophoroside 5:624 6-Hydroxyluteolin-7-sulphate 5:655 18-endo-Hydroxymakomakine 11:326, 327 12-Hydroxymalagashanine 26:1053 (+)- 1313-Hydroxymamanine 15:523 from Maackia amurensis 15:523 13[3-Hydroxymamanine 27:267 X-ray analysis of 27:267 (-)-baptifoline 27:267 6-3a-Hydroxymanool 25:275 14o~-Hydroxymarcfortine A 28:338 synthesis of 28:338 15ct-Hydroxymarcfortine A 28:338 synthesis of 28:338 16(x-Hydroxymarcfortine A 28:338 synthesis of 28:338 5-Hydroxymatairesinol 18:601 5-allo-Hydroxymatairesinol 18:601 cis-( 3R,4R )-(-)-4-Hydroxyme llein 15:383 (R)-(-)-5-Hydroxymellein 15:383
3-Hydroxymellein 15:383 4-Hydroxymellein 15:383 trans and c&-(3S,4S)-4-Hydroxymellein 15:531 6-Hydroxymellein 25:498,499,506,507 Hydroxymellein synthase 25:483,506 6-Hydroxyme llein-O-methyltrans ferase 25:483 Hydroxymenthol 25:155 5-Hydroxymethlmellein 9:288,289 Hydroxymethyl C-glycoside 10:338 reaction with butyl lithium 10:338 from glycal 10:338 reactions with tributyltinmethyl iodide 10:338 3-Hydroxymethyl cyclopentanone 6:558 from 3-oxocyclopentane carboxylic acid 6:558 cis-2-Hydroxymethyl cyclopentylamine 22:294 trans-2-Hydroxymethyl cyclopentylamine 22:294 Hydroxymethyl indole 4:7153in Mannich reaction 4:715 cis-Hydroxymethyl oxocane 10:233 synthesis of 10:233 24-Hydroxymethyl steroids 15:79 absolute configuration of 15:79 (24S,22E)-24-Hydroxymethyl-(cholesta5,22-dien-3 [3-ol 15:98 (R)-l-(Hydroxymethyl) ethyl 2-glyceryl ether 6:387 from 2-amino-2-deoxy-3-O-(R)[hydroxymethyl) ethyl]-c~-Dglucopyranose 6:387 (S)-5-(Hydroxymethyl)-2-pyrrolidinone 11:264 from (S) pyroglutamic acid 11:264 Ent- 12[3-Hydroxymethyl-3-oxo- 16norpimar-8( 14)-ene- 15,21carbolactone 9:283,284 2R-Hydroxymethyl-3R,4S-dihydroxypyrrolidine 10:549 chemico-enzymatic synthesis 10:549
408
from Angylocalyx boutiqveanus 10:547 from Arachiodes standishii 10:547 synthesis of 10:548-549 yeast c~-glucosidase inhibitor of 10:547 2-Hydroxymethyl- 8-hydroxanthraqu inone-3-O-[3-D-glucoside 26:660 Hydroxymethylacylfulvene 22:260 2-Hydroxymethylanthraquinone 3glucoside 26:657 2-Hydroxymethylanythraquinone-3-O[3-D-glucoside 26:660 Hydroxymethylbilane (preurog'en) (HMB) 9:591,592,595 24(S)-Hydroxymethyl-chole sta-5,22(E)dien-3[3-ols 15:51 Hydroxymethylglutaryl coenzyme A reductase 13:553 4-Hydroxymethyl-iridoids 7:467,468 2-Hydroxymethylquinizarin 26:661 3-Hydroxymethylvoacangine 5:128 14c~-Hydroxy-MFA 28:340 biological activity of 28:340 Hydroxymycotrienin 23:54 Hydroxymycotrienin A 23:76 34-Hydroxymycotrienin II 23:76 12-Hydroxy-myricanone 26:895 4-Hydroxymyrtenal 23:819 5-Hydroxy-N,N-dimehtyl tryptamine 25:531 3'-R/S-H ydro x y-N 4-demethyl erv ahanine 5:125 3'-R/S-Hydroxy-Na-demethyltabernamine 5:124 Hydroxynagilactone F 28:4752anti-fungal activity of 28:475 1,4-Hydroxynaphthalene 23:53 Hydroxynaphthoquinone atovaquone 26:783 Hydroxynaphthoquinone metal complexes 30:314 as antitumor agent 30:314 8-Hydroxy-naringenin 28:64 antioxidant activity of 28:64 16-Hydroxy-Nb-demethylalstophylline oxindole 9:196,197
O-Hydroxynitropapuline 26:593 2'-Hydroxy-N-methylschumannificine 21:140 Hydroxynomuciferine 26:825 11-Hydroxynoracronycine 13:348,349, 356-358,366,367,370 fromAtalantia ceylanica 13:348, 349,356-358 synthesis of 13:356-358 18-Hydroxynorfluorocurarine 1:38,39 4-Hydroxyochratoxin A 15:388 Hydroxy-octadecandienoates 9:566 Hydroxyoctadecatrienoic acid 1:534536 synthesis of 1:534-536 Hydroxyomoside 26:318,321,322,325, 333,343 N-Hydroxyovigerine 30:564,589 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 cytotoxic effect of 30:599 3 [3-Hydroxy-oxo-7c~,11[3H-germacra4Z, 10(14)-diene- 12,6c~-olide 27:561 (4E, 8E)-N-D-2 '-Hydroxypalmitoyl- 1-O[3-D-gluc op yrano syl-9-methyl-4,8sphingadienine 18:813 O-Hydroxypap' ~ne 26:592,593 3-Hydroxyparatocharpin Cg 28:228 biological activity of 28:228 313-Hydroxyparthenolide 27:566 10-Hydroxypatchoulol 25:171,172 7-Hydroxypeganine 25:532 6[3-Hydroxy-pentahydroxy-agarofurano 18:746 6-Hydroxyperezone 5:766,794,795 ~3C-NMR spectrum of 5:766, 794,795 transformations of 5:794,795 15-Hydroxyperezone 5:795,796 transformations of 5:795,796 1-Hydroxyphenazine 26:365 Hydroxyphenolic acid 25:657 4(4-Hydroxyphenyl)-2-butanone 4'-0-[3D-(2,6-di-O-galloyl) glucopyranoside 29:588 as phenolic glycoside 29:588
409 4(4-Hydroxyphenyl)-2-butanone 4'-O-13D-( 2- O-galloyl-6-O-cinnamoyl)glucoside 29:569 as phenolic glycoside 29:589 p-Hydroxyphenyl- 1-bromoheptadecane 26:73 (x-Hydroxyphenylacetaldehyde 6:316,317 synthesis of 6:316,317 Hydroxyphenylethanol 15:351 4m-Hydroxyphenylpropionic acid (m-HHA) 25:922,923,947 4-Hydroxyphenylpyruvic acid 30:221 dimerisation of 30:221 15-c~-Hydroxypristimerin 30:665,692 ~3C heteronuclear correlation of 30:665 13C NMR of 30:665 ~H heteronuclear correlation of 30:665 IH NMR of 30:665 MS of 30:665 ROESY experiment of 30:666 (+)- 1-Hydroxypinoresinol 5:523,533, 537,538,542;26:200,270 (+)- 1-Hydroxypinoresinol dimethyl ether 5:533-534,536 (+)- 1-Hydroxypinoresinol- 1- 13-Dglucoside 5:523,538,542 (+)- 1-Hydroxypinoresinol-4'-O-methyl ether 5:523,533-536 (+)- 1-Hydroxypinoresinol-4'- f3-Dglucoside 5:523 (+)- 1-Hydroxypinoresinol-di- [3-Dglucoside 5:523 10-Hydroxy-p-methoxybenzoate 5:725, 726 15-c~-Hydroxypristimerin 30:665,692 against HeLa (human carcinoma of cervix) 30:692 cytotoxic activity of 30:692 Hydroxypristimerinene 5:747,749 17c~-Hydroxyprogesterone 9:415,416 from androstenedione 9:415 6a-Hydroxypterocarpans sphenostylins B 7:413,414
6a-Hydroxypterocarpans sphenostylins C 7:413,414 6-Hydroxypyrano [2,3-c] acridin-7-ones (noracronycines) 13:348 Hydroxypyrrol-2(5H)-one 13:117,11833-Hydroxypyrrole-2-carboxylates 8:272 8-Hydroxyquinaldic acid 26:991 microbial transformation of 26:991 8-Hydroxyquinaldic acid 26:991 8-Hydroxyquinoline 2:244;5:752;9:540 12-Hydroxyretulinal 1:36 3c~-Hydroxyreynosin 27:555 3-Hydroxyrifamycin S 23:61,81 30-Hydroxyrifamycin W 23:61 18-Hydroxysacculatal 2:278,279 19-Hydroxysacculatal 2:278,279 3-Hydroxysampangine 23:3,6 4-Hydroxysampangine 23:6 8etHydroxysantamarine 27:556 15-Hydroxysantonin 24:124,125 Hydroxysantonin 24:54,55 (+)- 13a-Hydroxysepticine 12:278 5-Hydroxysiastatin 16:86 from bovine liver 16:86 7~-Hydroxysitosterol 25:56 diacetate 25:56 2313-Hydroxysolanidine (leptinidine) 7:18,22 13a-Hydroxyspeticine 12:301 12(x-Hydroxyspongia- 13(16), 14-diene 1:662,663 synthesis of 1:682,683 (+)- 12(x-Hydroxyspongia- 13(16), 14diene 6:111,116 synthesis of 6:111,112,115,116 7-Hydroxystaurosperine 12:366,368 from Streptomyces sp. N- 126 12:366,368 11-Hydroxystaurosperine 12:366,370 from Eudistoma sp. 12:366,370 7c~-Hydroxystaurosporine 21:264 11-Hydroxystaurosporine 23:259 8-Hydroxystearic acid 21:188 24-Hydroxysteroids 15:76,77 absolute configuration of 15:76,77
410 26-Hydroxysteroids 15:77,78 absolute configuration of 15:77,78 313-Hydroxy-sterols 25:96,299,303 3-Hydroxystigmastan-6-one 9:288,289 N-Hydroxysuccinimidocarbonate 21:162 6a-Hydroxysugiol 29:99 activity in EBV assay system 29:99 (+)- 1-Hydroxysyringaresinol 5:524, 535-538 3-Hydroxytabernaelegantine 5:129 19R-Hydroxytabernaelegantine B 5:129 17-Hydroxytabersonine 4:57,58 19S-Hydroxytacamine 5:128;9:179 17-Hydroxytacamonine 5:126;9:180 7-Hydroxytectoquinone 26:661 2-Hydroxytetradecanoic acid 21:188 5-Hydroxytetrahydroharmane 5:125 Hydroxythymoquinone 5:763 3-Hydroxythymoquinone 5:767 6-Hydroxythymoquinone 5:767 20-Hydroxytingenone 30:668 IH NMR spectral data of 30:668 13C NMR spectral data of 30:668 NOE experiments of 30:668 stereochemistry of 30:668 20Gt-Hydroxy-tingenone 30:696 assay of 30:696 structure of 30:696 Hydroxy-tingenone 30:696 effect on feeding activity 30:696 effect on larvae development 30:696 effect on mortality 30:696 20-Hydroxytingenone 5:744,746,747 22-Hydroxytingenone 7:146 Hydroxytingenone 7:149 25-chloro-24-Hydroxytiruc all-7-en-3one 30:658 13C NMR of 30:658 HMBC spectrum of 30:658 molecular formula of 30:658 7-a-Hydroxy-tomatidine 25:318 16a-Hydroxytrametenolic acid 3-Oacetate lanostanes 25:63 I6a-Hydroxytrametenolic acid-3-Oacetate 25:61
3a-Hydroxytrichothecene 6:229,247 from 3-ketotrichothecene 6:229 6a-Hydroxytriptocalline A 30:641 structure of 30:641 3c~-Hydroxytropane 22:717 Hydroxytryptamine 30:37 structure of 30:370 Hydroxytropylium ion 1:568 5-Hydroxytryptamine 21:10;22:21; 30:370,384 [3H]-5-Hydroxytryptamine 25:31 5-Hydroxytryptamine 5:125;15:328; 25:529,531 5-Hydroxytryptophan 6:319;30:369, 370,371 structure of 30:369,370 5-Hydroxytryptophan 5-Hydroxytryptophan(5-HT) 30:384 3ot-Hydroxy-urs-12-ene 22:103 fl-Hydroxy-urs-12-ene 22:1033 11-Hydroxy-valenc- 1( 10)-en-2-one 23:635 Hydroxyvalidamine 10:518;13:189, 195,197 19-Hydroxyvandrikine 9:193 Hydroxyverniladin 26:808 Hydroxyvinamidine 2:389,390,398 14c~/14[~-Hydroxyvincadifformine 14:831 12-Hydroxyvincadifformine 5:124 15[~-Hydroxyvincadifformine 5:169-171 19-Hydroxyvincamajine 5:155,156 lc~-Hydroxy-vitamin D 10:45,49 1a-Hydroxyvitamin D analogues 30:485 structures of 30:485 1c~-Hydroxyvitamin D2 11:381-383, 385,395,402 l[3-Hydroxyvitamin D2 11:402-404 synthesis of 11:402-404 25-Hydroxyvitamin D2 9:512,513,515, 520,521;11:381 24-Hydroxyvitamin D2 9:513 1[~-Hydroxyvitamin D3 11:402-404 25-Hydroxyvitamin D3 12:401 1a-Hydroxy-vitamin D3 9:518,519
411 1a-Hydroxyvitamin D3 ((1 S)hydroxycalciol) 11:380,381,385, 395,402 25-Hydroxyvitamin D3 (calcidiol) 11:380,388-393 11-Hydroxyvittatine 26:610 3-Hydroxyvoacangine 5:124 6ot-Hydroxyvouacapan- 17,713-1actone 29:103 activity in AOS bioassay system 29:103 Hydroxywilfordic acid 23:674 4-Hydroxywithanolide E 20:223 14[3-Hydroxywithanone 20:180,242 Hydroxyxanthone 25:327,349,354,361 (-)-6'-Hydroxyyatein 26:192,212; 30:569,587 cytotoxicity of 26:212 dibenzylbutyrolactone-type lignan 30:587 ~H NMR spectrum of 30:587 lH-1H COSY of 30:587 HREIMS of 30:587 IR spectrum of 30:587 molecular formula of 30:587 NOESY of 30:587 UV absorption of 30:587 11-Hydroxyyohimbine 22:9 15-Hydroxy-Z-5,Z-8, Z- 11,E- 13eicosatetraenic acid methyl ester 2:12 2-Hydroxyzanthone 5:759 x-Hydroxy-c~,13- unsaturated aldehydes 7:459,460 8-Hydroxy-a-humulene 29:91 activity in EBV assay system 29:91 o~-Hydroxy-13-amino acid 12:493 synthesis of 12:493 [3-Hydroxy-[3-eudesmol 27:558 (R)-c~-Hydroxy-[3-phenyl propionate 12:479 (3R,4S) statine from 12:479 Hydrozirconation 10:59;13:486 Hydrozyindolizidine 12:293 8Hygrine 22:724 (+)-Hygroline 7:192
Hylauronidase 25:47 inhibition of 25:47 Hylobius abietis 27:385 Hylomecon genera 27:163 Hylophora cecropia 22:383 Hymenaceae sp. 25:252 Hymenaea ablongifolia 25:252 Hymenaea courbaril 22:66 Hymenaea parvifolia 25:252 Hymenamide F 25:830,863 Hymeniacidon aldus 21:270 Hymeniacidon sp. 21:349;25:713,797, 798,799,830 Hymenialdisine 21:270,271,285; 25:711,787,795 Hymenidin 21:270 Hymenin 21:68;29:91 activity in TPA assay system 29:91 Hymenolepis nana 26:484 Hymenomycetes 9:202,203 Hymenoptera 21:612;22:371 Hymenoxys turneri K. Parker 15:32; 27:17,18,35 (2R, 3R)-Dihydroquercetin 3-0acetate from 27:17 (2R, 3R)-2,3-Dihydro-5,7,3 '-4'tetrahydroxy-6-methoxy-3-Oacetylflavanol from 27:17 (2R, 3R)-2,3-Dihydro-5,7,3 ',4'tetrahydroxy-6-methoxyflavanol from 27:17 (2R, 3R)-2,3-Dihydro-5,7,4'trihydroxy-6-methoxy-3-Oacetylflavanol from 27:18 Hymeriacidon sp. 25:870 Hyodeoxycholic acid 16:352 Hyophyllanthin 26:233 Hyosciamus 22:422 Hyoscyamine 11:204,206;13:662; 17:398-400,417 from phenyl alanine 11:204,206 (S)-tropic acid moiety of 11:204,206 613-Hyoscyamine 13:662 L-Hyoscyamine 21:104 Hyoscyamine 21:56,98,109 (+)-Hyoscyamine 22:718,726,730,735, 741,742
412
Hyoscyamus albus L. 17:398;22:742 Hyoscyamus genus 17:395 Hyoscyamus muticus 22:742 Hyoscyamus niger 13:631;22:523,721, 732,734,742 for epilepsy 22:523 Hyoscyamus niger 22:523 for epilepsy 22:523 Hyoscyamus sp. 21:104,488 Hypaconite 24:898-899 neuromuscular blocking effect 24:898-899 Hypaconitine 24:898-900 in neuromuscular blocking effect 24:898,899 Hypecoideae 27:161 Hypecorine 6:494 Hypecoum genera 27:163 Hypecoum imberbe 27:167,168 Hypecoum leptocarpum 27:168 Hyperbrasilone 23:343 Hypercalcemic activity 30:497 of 24-epi-1 et,25(OH)2Dz 30:497 of lc~,25(OH)zD7 30:497 Hypercholesterolemia 21:212,669; 22:250,252 c-rt-Hyperconjugation 12:454 Hypercytokinemia 25:463 Hyperenone-A 5:759 Hyperenone-B 5:759 Hyperevolutin A 22:656 Hyperevolutin B 22:656 Hyperforat 22:691 Hyperforin 22:645,646,650,652,654, 658,669,678,696;25:537,538;30:611, 627,628 against Bacillus cereus 30:628 against Bacillus subtilis 30:628 against gram-positive bacteria 30:628 against Staphyllococcus aureus 30:628 alkylation of 30:627 by acylation 30:627 chemical structure of 30:611 cleavage of 30:611 effect on re-uptake of neurotransmitters 30:627
HPLC-ESI analysis of 30:611 MS n analysis of 30:611 oxidation of 30:627 Hyperforin derivatives 7:420,421 Hyperforin inhibitors 30:627 in depression 30:627 serotonin as 30:627 dopamine as 30:627 noradrenaline as 30:627 GABA as 30:627 Hyperici oleum 22:652 Hypericin 22:644,648,664,670,673,675, 678,683,684,685 ;26:375 ;27:850,851; 30:345,607,608,624,626-628 against herpes simplex virus types I and II 30:627 against retrovirus 30:627 against vesicular stomatitis 30:627 as antibiotic from 30:628 as inhibitor 30:626 as inhibitor of virus replication 30:628 as photoreceptor 30:607 as virucidal agents 30:627 in vivo virucidal efficacy 30:628 mechanism of action of 30:626 minimum inhibitory concentrations (MIC) 30:628 retroviral activity of 7:421 use for mild depression 30:345 use for moderate depression 30:345 virucidal effect of 30:627 Hypericoideae 30:604 Hypericum annulatum 7:417;30:611, 616,619,624 acetylannulatophenonoside from 30:624 annulatophenonoside from 30:624 glycosilated benzophenone from 30:624 phloroglucinol from 30:616 phytochemical studies of 30:611 terpenoid moieties from 30:616 Hypericum ascyron 30:620 in treatment of abscesses 30:620 in treatment of headache 30:620
413
in treatment of nausea 30:620 xanthones from 30:620 Hypericum barbatum 22:656;23:343; 30:607,611,629 against Bacillus subtilis 30:629 hydrocarbons from 30:607 prenylated phloroglucinols from 30:611 phloroglucinols from 30:629 terpenes from 30:607 Hypericum calycinum 7:422;26:797; 30:619 calycinoxanthon D from 30:619 phloroglucinol from 26:797 xanthones from 30:619 Hypericum chinense 7:422;22:656 Hypericum compound H8 (prenylated xanthone) 29:579,581 effects on ACE 29:579 effects on NEP 29:581 Hypericum drummondii 22:657;30:611 prenylated phloroglucinols from 30:611 Hypericum elegans 30:606 tlypericum erectum 24:273 Hypericum extracts 30:626 in vitro 30:626 inhibitor of dopamine 30:626 inhibitor ofnoradrenaline 30:626 inhibitor of monoamine neurotransmitters 30:626 inhibitor of serotonin 30:626 Hypericum geminiflorum 30:622 2,3-dihydroxy- 1,6,7-trimethoxyxanthone from 30:622 3,6-dihydroxy- 1,5,7-trimethoxyxanthone from 30:622 6,7-dihydroxy- 1,3-dimethoxyxanthone from 30:622 gemixanthone from 30:622 Hypericum genus 30:603 bioactivity of 30:603 secondary metabolites from 30:603 Hypericum hirsutum 22:675,647; 30:606,619 biflavone from 30:619 flavonoids from 30:619
Hypericum humifusum 30:606,619 flavonoids from 30:619
Hypericum hyssopifolium 22:672 Hypericum inodorum 30:619 xanthones from 30:619
Hypericumjaponicum 5:758;22:657; 30:611,614,629 antimicrobial activity of 30:629 as herbal drug 30:614 for gastrointestinal disorders 30:614 for hepatitis 30:614 in diseases 30:614 in treatment of bacterial infections 30:614 prenylated phloroglucinols from 30:611 Hypericum maculatum 22:647;30:619 flavonoids from 30:619 Hypericum montanum 30:606,619 biflavone from 30:619 flavonoids from 30:619 Hypericum mysorense 5:758,759; 30:629 against Bacillus coagulans 30:629 against Bacillus megatorium 30:629 against Bacillus subtilis 30:629 against gram-positive organisms 30:629 against Staphyloccus aureus 30:629 Hypericum nummularium 22:647 Hypericum olympicum 30:619 flavonoids from 30:619 Hypericum papuanum 30:616 in treatment of sores 30:616 papuaforins A-E from 30:616 prenylated phloroglucinols from 30:616 tricyclic acylphloroglucinols from 30:616 Hypericum patulum 30:619,622,629 against Eisenia coli 30:629 against Pseudomonas cepacia 30:629 flavonoids from 30:619
414
Hypericum perforatum 5:656,758; 21:541 ;22:643,653,661,664,666,672, 673,675,676,679-690;25:557;29:580; 30:407,603,604,605,609,610,616, 618,619,622,624,626-629 against infected wounds 30:628 against skin lesions 30:628 antimicrobial activity of 30:628 antiviral activity of 30:407,627 biflavone from 30:619 cell cultures of 30:609 chemotaxonomic study of 30:619 constituents of 30:605 extract of 30:624 flavonoids from 30:616,618 HPLC of 30:624,626 hyperoside from 30:618 m depression treatment 30:624, 629 in treatment of abdominal pain 30:603 in treatment of isoquercitrin from 30:618 in treatment of melancholia 30:603 m treatment of ulcerated burns 30:603 in treatment of urogenital pain 30:603 lsovaleric acid from 30:605 mechanism of action of 30:624 parts of 30:609 paxanthone from 30:622 pharmacology of 30:624 phenotypic characters of 30:604 phloroglucinols from 30:610 c~-pinene from 30:605 quercetin from 30:618 quercetin-arabinoside from 30:616 quercetin-galacturonide from 30:616 quercitrin from 30:618 rutin content of 30:616 rutin from 30:618 subspecies of 30:604 var. angustifolium 30:604 var. microphyllum 30:604
var. perforatum 30:604 varieties of 30:604 veronense from 30:604 volatile oil from 30:605 xanthones from 30:619 Hypericum pulchrum 30:606 Hypericum revolutum 7:409,410,417, 420-422;22:655 ;23:342 Hypericum roeperanum 29:581 ;30:619, 620 (5-O-demethyl paxanthonin) from 30:620 calycinoxanthon D from 30:619 roeperanone from 30:619 xanthones from 30:619 Hypericum sampsonii 30:622 against diarrhoea 30:622 against snake bites 30:622 against swellings 30:622 Hypericum sarothra 30:605 n-nonane from 30:605 Hypericum scabrum 30:616 hyperibones A-I from 30:616 Hypericum sp. 27:850 Hypericum tatrapterum 30:606,619 flavonoids from 30:619 Hypericum triquetrifolium 22:647,673 Hypericum uliginosum 22:657 Hyperin 7:227 Hyperkinetic ventricular arrhythmias 25:594 Hyperlipemia 22:607,608 Hyperlipidaemia 27:405;30:55,56,58, 70,83,88,98,101 biological activity of 27:405 due to high-fat diet 30:98 in mice 30:101 prevention of 30:56 role of natural products in 30:55 treatment of 30:56 use of Ganoderman lucidum in 30:58 use of Laminaria japonica Aresch in 30:56 use of orlistat (Ro 18-0647) in 30:83 use of Platycodi radix 30:88 Hyperosid 22:645;26:666
415 Hyperplasia 30:375 of cerebral grey matter 30:375 of cerebellae white matter 30:375 Hyperpolarisation 21:101 Hypersensitive response 25:394,402; 27:61 Hyperserotonemia 30:381,368 in autism 30:381 Hyperstable olefins 12:207 Hypertension 30:55,58,72,201,368 role of Angelica keiskei in 30:72 role of Ganoderman lucidum in 30:58 role of natural products in 30:55 role of serotonin (5-HT) in 30:368 Hypertrehalosaemic hormones 9:487 Hyphochytridimycetes 9:202 Hyphomonasjannaschiana 25:873 Hyphomycetes 9:203 Hypnophilin 3:7,65;22:195,202,208 Hypocholesterdemic effects 25:222 ofsoyabean saponins 25:222,223 Hypocholesterolemic agent 13:554; 21:616;26:246 Hypocholesterolemic atherosclerosis 26:248,249 Hypocholesterolemic drug 5:195 Hypocholesterolemic effect 26:44,54, 205 of Gypsophila capitala 26:44 Hypocholesterolic effects 26:233 Hypocholorous acid 25:931 Hypocrea muroiana 21:225 hypomurocins A,B from 21:225 Hypocrea sp. 21:203,224 Hypodiol 30:646 IH-IH COSY of 30:647 HMQC of 30:647 HOHAHA spectra of 30:647 NMR spectroscopic data of 30:646 NOESY spectrum of 30:647 stereochemistry of 30:647 structure of 30:647 Hypoglottis 27:61 Hypoglycemic effect 30:80,94,294 of Ajuga iva (L.) 30:294
of saponon 30:94 of tea saponin 30:80 Hypoglycemic activity 18:672;21:460, 488,666;26:398 Hypoglycemic agent 21:459,488 phytochemicals as 21:457 Hypoglycemic effects 17:139 Hypoglycin A 26:476 Hypolactin-6-glucoside 25:613 Hypolactin-8-glucoside 25:612,616 Hypolaetin 5:665;22:434,440 Hypolaetin-3'-methyl ether-7-glycosides 5:658 Hypolaetin-8-glucoside 22:434,440 Hypolepis puncatata 26:122 Hypolipaemic drug 5:695 Hypolipidaemic effects 27:400 Hypolipidemic action 26:887 Hypolipidemic activity 23:357;26:247 of scoparone 23:357 Hypoloside A&B 26:722 Hypooxidaceae 25:180 Hypoponera opacior 5:224,230,254 Hypopyhyllanthin 17:344 synthesis of 17:344 Hyporeales 9:203 Hypotensive action 28:200,209,207; 30:787 of isoprenylated flavonoids 28:207 ofkuwanon G 28:209 ofkuwanon H 28:200,209 mechanism of 30:787 ofMorus alba 28:200 of Morus species 28:207 ofmulberrofuran C 28:209 of mulberrofuran F 28:209 of mulberrofuran G 28:209 Hypotensive activities 17:451 ;21:690; 27:481 of Astragalus membranaceus roots 27:481,483 of cryptolepine 5:752 Hypotensive alkaloid 5:751,752 Hypothalamic neuropeptide 27:794 Hypothalamus 22:25 Hypothalamus-pituitary 27:794
416
Hypothermal activity 23:353 of Coumarin 23:335,353,356, 357,368,376,393,550,553 Hypothermia 30:194 due to opioids 30:194 Hypothermic activity 23:800 Hypothetical incorporation 11:195 of methylmalonyl CoA 11:195 with macrolide antibiotic 11:195 with polyether antibiotic 11:195 Hypothyroidism 30:374 autistic features in 30:374 Hypotriglyceridemic effect 26:246,261 Hypoxanthine 15:460;22:314 [G-H]Hypoxanthine 25:348 Hypoxanthine-guanine-phosphoribosyltransferase 15:371 Hypoxanthine-H 23:199 9-D-Hypoxanthines 4:224,225 Hypoxylon oceanicum 25:717 Hypselodoris californensis 6:20 curyfuran from 6:20 Hypselodoris godefroyana 6:69 curyfuran from 6:20 nakafuran-9 from 6:29 Hypselodoris nana 25:815 Hypselodoris porterae 6:20 Hypselodoris webbi 21:361 Hypselodory nana 26:463 Hypsochromic shift 30:539 Hyptis verticillata 21:599;26:212; 28:402 dehydro-[3-peltatin methyl ether from 26:212 5-methoxypodophyllotoxin from 26:212 Hyriopsis schlegelii 26:1123 Hyrtiomanzamine 25:710,819;28:691 immunosuppressive activity of 28:691 Hyrtios altum 25:727 Hyrtios erecta 25:696,698,710,819; 28:691 Hyrtios eubamma 6:23 puupehenone from 6:23 Hyrtios sp. 25:716 Hyrtios spicigora 25:276 Hysistozoa fasmeriana 28:635 Hysselodoris californiensis 4:404
Hysselodoris porterae 4:404 Hyssopus 26:746;29:579 Hyssopus officinalis 7:119 Hysteria 22:510,512,513,516,518,519, 521,522,525-529,531,534
A chyranthes aspera L. for 22:510
Acorus calamus L. in 22:510 Anagallis arvensis L. for 22:512 Asarum maranthuym Hook. for 22:513
Cinnamomum camphora for 22:516
Cynodon dactylon L. for 22:516, 518
Dictamnus albus L. 22:519,521 Ferula alliacea for 22:521 Flemingia strobilifera for 22:521 Galium verum L. for 22:521 Hibiscus abelmoschus L. for 22:522
Linum usitatissimum L. for 22:525
Lobelia inflata L. for 22:525 Martynia chamomilla L. for 22:526
Matricaria aurea L. for 22:526 Melissa offlcinalis L. for 22:526 Moringa oleifera for 22:526 Musa paradisiaca L. for 22:526 Nordostachysjatamansi DC. For 22.'527 Olacaceae for 22:720 Paeonia emodi for 22:528 Paeonia officinalis L. for 22:528,529 Peganum harmala L. for 22:529 Ruta graveolens L. for 22:531 Sapindus trifoliatus L. for 22:531 Valeriana hardwickii for 22:534 Valeriana officinalis L. for 22:534 Valeriana wallichii for 22:534 Hysterin 29:90 activity in TPA assay system 29:90 Hystero-epilepsy 22:513,525,527,528, 531,532,534
417
Benincasa hispida use for 22:513 Mangifera odorata L. for 22:525 Nardostachysjatamansi DC. For 22:527 Paeonia emodi for 22:528 Sapindus trifoliatus L. for 22:531 Semecarpus anacardium L. for 22:532 Valeriana hardwickii for 22:534 Valeriana officinalis L. for 22:534 Valeriana wallichii for 22:534 Hystiomanzamin 25:819 Hytakerol 9:513 Hytis spicigora 25:276 IAA oxidase 25:657 Ianchinenoside E 26:38 c-AMP phosphodiesterase inhibitory activity of 26:38 Ianthella basta 25:719;28:695,714 as Ca2+-channel agonists 28:695 Ianthella flabelliformis 28:714 Ianthella sp. 28:695 Iantheran A 28:695 as Na+/K+-ATPase inhibitor 28:695 Iberis amara 19:762,20:12 Iberis umbellata 29:53 Ibhaynid 25:802 Ibisterol sulfate 28:700 against HIV-1 28:700 Iboga alkaloids 1:112,93-96,163165,422 Ibogaine 5:101,126,174;21:70,72,95; 22:18,24,435,542;25:533,537 as immunosuppressive drug 25:533,537 Ibogaine hydroxyindolenine 5:101,126 Ibogaine pseudoindoxyl 5:126 Ibogaline 5:127,174 dl-Ibogamine 14:806,807 Ibogamine 25:533,537 as immunosuppressive drug 25:533,537 (-)-Ibogamine 5:124
(+)-Ibogamine 5:125 Ibogamine pseudoindoxyl 5:126 Ibogan 26:139 Ibogan-type alkaloids 5:71 Ibophyllidine 5:126,847;9:190,192 synthesis of 14:847 2--epi-Ibophyllidine 5:126 Ibophyllidine-Na-oxide 5:126 Ibophyllidine-type alkaloids 5:100 desethylibophyllidine 5:100 19-hydroxyibophyllidine 5:106 18-hydroxy-20-epiibophyllidine 5:106 19R- 19-hydroxy-20-epiibophyllidine 5:106 19S-19-hydroxy-20-epiibophyllidine 5:106 ibophyllidine 5:106 20-epi-ibophyllidine 5:106 19S-iboxygaine 5:106 Ibotenate 25:531 19-epi-Iboxygaine 5:126 Iboxygaine hydroxyindolenine 5:127 19-epi-Iboxygaline 5:127 Iboxyphylline 14:847 synthesis of 14:847 Ibuprofen 30:192 as cyclooxygenase enzyme (COX) inhibitor 30:192 Ibuprophen 6:322,323 ICAM-1 expression 30:70,71 inhibitory effect on 30:70,71 Ichikawa 29:492 carbaoxirose/carbaoxetoses synthesis by 29:492 Ichorati 17:200 Ichthyotoxic 21:267,275,365 Ichthyotoxic activity 28:698 ofhalistanol sulfate 28:698 Ichthyotoxic agent 21:267,275,365 Ichthyotoxic malyngomides 25:757 Ichthyotoxicity 17:24;18:607,716 Ichthytoxic activity 25:768;26:485 Ichtyotoxic agent 25:730 Icosanoid 25:945 all, cis-5,8,11,14,17-Icosapentaenoic acid 21:306 Icosapolyenoic acids 9:559 Icosatetraenoates 9:566
418 (5,8,11,14Z)-Icosatetraenoic acid 9:560 Icosatetraynoic acid 9:564 8,11,14-Icosatrienoic acid 9:577 Icsatrienoic acid (dihomo-T-linolenic acid) 9:564 Ictalurus punctatus 26:353 IDDM 21:458 Idicol 26:850 L-Idopyranose analogs 6:369,370,372, 373 Iedania ignis 28:692 Iejimalides (A-D) 10:247,19:606 IFN- T 21:651,666;25:465 IFN-c~ 21:651,656 IG isotypes 24:168-170 IgE production 30:773 inhibition of 30:773 against casein 30:773 IgE/anti Ig E complexes IgGl-antibodies 21:646 IgG2a-antibodies 21:646 Iguesterin 5:747,18:757,776 (+)-Ikarugamycin 21:411 Ikarugamycin 4:620;10:153,18:10-17; 23:51 ;28:138,140 anti-bacterial activity of 28:140 antiprotozoal activity of 28:138 biosynthesis of 4:620 Ikegami 29:485 valiolamine synthesis by 29:485 IL (Interleukin) 25:455 IL- 1ct 30:689,771 inhibitory activity of 30:689 IL-113 30:689 inhibitory activity of 30:689 IL-2 production 30:782 by macrophages/dendritic cells 30:782 by TLR2 signaling 30:782 Ileostylus micranthus 28:454,464 Ilex aquifolium L. 20:6;22:523 for epilepsy 22:523 Ilex crenata 21:657 ilexosides A,B,C and D from 21:657 18,19-seco-ursane glycosides from 21:657 Ilex lactone 20:6
Ilex paraguariensis 20:6;21:671;27:299 Ilex verticillata 9:402 Ilicic acid 29:87 activity in TPA, AA, EPP assay systems 29:87 Ilicicolin H 4:620 biogenesis of 4:620 Ilicifoline 23:695 Ilimaquinone 5:430;15:291,314 absolute configuration of 5:430 antimicrobial activity of 5:434, 437 5-epi-Ilimaquinone 9:31;15:315,319 oxidative degradation of 9:31 Illicic acid (vachanic acid) 7:212 Illicium verum Hook f. 21:596;27:16 trans-anethole from 27:16 Illudanes 26:705 Illudin M 22:260;26:706 Illudin S 22:260 Ilybius fenestratus 5:780 Imanine 30:628 antibacterial properties of 30:628 Imberic acid derivatives 25:183 Imbricatine 7:306,307 Imbricatosides A 15:64 Imelutine 1:167 Imidazole 12:152;25:335 Imidazole [4,5-e-]-l,2-thiazine 25:897 Imidazolidines 1:349-351 2-azaallyl anions from 1:349-351 Imidazolidinone 8:156 Imidazolo [4,3-a] isoquinoline 12:447 Imidazolone 5:412 cytotoxic activity of 5:413,415 Imide enolates 12:164-168 4-acetoxy-13-1actam with 12:164-168 C4-alkylation with 12:164-168 from propionic acid derivatives 12:164-168 Imidoyl chloride 14:157 Imidoyl phosphate 8:79 synthesis of 8:79 Imine 12:173 [2+2] cycloaddition of 12:173 azaallyl anions from 1:331-344 cis reduction of 6:428
419
deprotonation of 1:331-344 preparation by Standinger reaction 1:352-353 trans reduction of 6:428 trans-3-acetyl-[3-1actam from 12:173 with diketene 12:173 ylides from 1:331-334 9-N- [2- Sulfoethyl)Imine 25:870 Iminium 'A' 2:390,2:398,402 Iminium 'B' 2:390,390 Iminium cyclization 1:243 Iminium ion cyclization 1:286,287 to vinylsilanes 1:286,287 Iminium ion-vinylsilane 19:52 Iminium ion-vinylsilane cyclization 12:454 ~-Imino carboxylic acid 8:384 2-Imino cyclic ethers 10:215 synthesis of 10:215 Imino Diels-Alder approach 14:732,733 Imino Diels-Alder reaction 4:36,37,604 13-Imino sulfoxide substrate 18:382 5,8- Imino- 7- O-me syl- 2,3,5,8-tetradeoxy-D-glucooctano- 1,4-1actone 12:325 Iminodienophile 4:604 in Diels-Alder reaction 4:604 Iminogalactitol 7:42 Imipenem 4:432;12:145 antibiotic potency of 4:432 N-formimidoly derivative of theienamycin 12:145 PBP-2 affinity for 4:433 Imipramine 22:672 Immobilised cultures 7:92 Immobilized glucoamylase 2:356 Immune disorders 30:484 use of l cx,25(OH)2D3 30:484 Immune response 30:766,770 against Listeria monocytogenes 30:770 by cx~ T cells 30:766 Immune-active acidic glycoprotein 25:455 from Chlorellavulgaris 25:455 Immune-mediated cytotoxicity 21:656; 25:467
Immune-suppression mycosis 22:56 Immunization 30:408 against measles 30:408 Immunoadjuvants 21:646 saponins as 21:646 Immunoadjuvant monophosphoryl lipid A in 18:918 Immunoadjuvant properties 6:385 Immunoadjuvant saponins 21:646 Immunoaffinity chromatography 25:382 Immunoassay screen 19:188 Immunoblotting 25:499 Immunocompetent organ toxicity 28:561 chitosan inhibitory effect on 28:561 Immunocompetent organic toxicity 27:436;28:560 of5-fluorouracil (5-FU) 28:560 Immunodeficiency syndrome 30:226, 394 causative agent of 30:394 Immuno-deficiency virus 22:646,648; 25:734;30:397 use of HIV-1 30:397 use of HIV-2 30:397 Immunodulatory activity 30:395 ofpolysaccharide (PS) 30:395 Immunofluorescence detection 26:935 of the putative NOS 26:935 Immunofluorescence microscopy 26:932 Immunogens 18:909-920 Immunoglobulin G 22:374;30:837 F-II hydrolysis of 30:837 Immunoglobulins 24:140-144 Immunohistochemical staining 25:442 Immunohistopathology 26:792 Immunological activity 23:107 of fungal [3-glucans 23:107 Immunological assays 15:361 Immunological role 30:422 of 3-deoxyulosonic acids 30:422 stereocontrolled chemical syntheses in 30:422 Immunomodulating action 24:131, 149-152 Immunomodulator activity 21:316,645; 23:129,687
420
of fungal B-glucans 23:129 Immunomodulation 7:16 by swainsonne 7:16 Immunomodulatory actions 26:1036 Immunomodulatory effect 21:134; 26:31,50,55 of Acanthophyllum squarrosum 26:55 of Gypsophila saponins 26:55 of squarroside A 26:31 ofVaccaria segetalis 26:50 Immunopathological reactions 26:787 Immunopharmacology 30:766 of Chlorella 30:766 of green algae 766 Immunopotentiating effects 25:429 of Chlorella vulgaris strain CK 22 (CVs) 25:429 Immunoprecipitated CDK2 kinase 21:136 Immunoreactive polypeptide 25:383 Immunosorbent assay 15:361 Immunostimulant effect 27:513 ofpolysaccharide 27:513 of Astragalus membranaceus 27:513 Immunostimulant saponins 21:646,651 Immunostimulating action 24:131, 144-148,153,171 Immunostimulating complexes 21:648 Immunostimulating saponins 24:131-171 Immunosuppressant agents 16:561 Immunosuppressants 22:248 Immunosuppressive activity 18:739, 921 ;23:522,649,681 ;26:214,482 of didenmins 10:257,258 of diterpene triepoxides 23:649 of euonine 23:681 of sesquiterpene pyridine alkaloids 23:649 of verbascoside 23:522 of wilfortine 23:681 of [3-apopicoropodophyllin 26:214 Immunosuppressive agent 22:527;30:3 discodermolide as 30:3 pironetin as 30:3 Immunosuppressive disease 30:396
Immunosuppressive drugs 21:661 ; 25:464 FK 508 as 25:464 dexamethasone as 25:464 amphetamine as 25:537 calebassine as 25:528 carcurine as 25:528 coronaridine as 25:533 eseramine as 25:536 eseridine as 25:536 harmaline as 25:537 harmine as 25:537 ibogaine as 25:533,537 ibogamine as 25:533,537 physostigmine as 25:536 physovenine as 25:536 reserpine as 25:538 sapargine as 25:528 strychnine as 25:530 tabemanthine as 25:533 toxiferine as 25:528 yohimbine as 25:530 Immunosuppressive effect 26:486;30:26 on blastogenesis 30:27 of pironetin 30:26 Immunosuppressive therapy 20:528 Immunotherapy 28:543 detox for 28:543 Immunotoxicity 28:562;30:56 by doxorubicin 28:562 due to cancer drug chemotherapy 30:56 Immunstimulatory activity 26:797 Impatiens repens 22:523 for epilepsy 22:523 Imperata cylindrica 26:233 graminone B from 26:233 Imperialine 21:56;22:19 in regulation of methyl CpG binding protein 30:373 In vitro 28:470,467;30:59,61,396,594, 596,810,815,816 antiplasmodial activity 30:596 antiplasmodial activity of chloroquine 30:596 antiplatelet aggregation turbidimetry assay 30:594 DNA synthesis 30:61 glycopeptides 30:815
421
HIV replication 30:396 Lewis lung carcinoma 30:59 of glycopeptides 30:816 of milanjilactone A 28:470 ofmilanjilactone B 28:470 ofnagilactone F 28:470 ofnagilactone G 28:470 ofpodolactones 28:467 receptor binding assay 30:810 In vitro bioassay 30:591 for chemopreventive activity 30:591 In vitro studies 30:61,195,203,593,597, 805,815 of anandamide 30:195 ofangiogenesis 30:61 of antinociception 30:805 of chloroquine potentiating antiplasmodial activity 30:597 of ginseng extract 30:203 of ginsenosides 30:203 of glyco analogues activity 30:817 ofherveline A 30:597 of mouse fail-flick assay 30:815 of parasitemia inhibitor 30:597 of tetrahydrocannabinol (THC) 30:195 of tumor-promotion 30:593 In vivo testing 24:491 of anti-viral agent 24:491 Inactivation pathway 27:321,345 of ABA 27:345 INADEQUATE 21:692 2D INADEQUATE spectrum 2:96,98 of dammmaran-20 (S) of 2:96,98 of salculaplagin triacetate 2:88 INADEQUATE spectrum 24:237,280 of euglobal-G2 24:237 Incartine 20:351 from Lycoris incarnata 20:351 Incarvillateine 30:204 as antinociceptive agent 30:205 from Incarvillea sinensis 30:204 inflammatory pain inhibition by 30:205 neurogenic pain inhibition by 205 Incarvillea sinensis 30:204 incarvillateine from 30:204
Indanoaziridine 1:189 from isoquinolinium betaine 1:109 Indanomycin 10:348 synthesis of 3:275,276 Indanone 11:115 Indaquassin-C 23:299 Indazole dione 2:215,217 Indenobenzazepine 1:218,219 biogenesis of 1:218,219 from 8,14-cycloberbines 1:209-211 from spirobenzylisoquinolines 1:207-208 oxidation of 1:216 reaction with Lewis acids 1:196,197 rearrangement to spirobenzylisoquinoline 1:205,206 synthesis of 1:196,197,205,206 trans-to-cis-isomerization 1:210 anti-Indenofluorenone 11:124 from 1,2,4,5-benzenetetra carboxylate 11:124 ~H-NMR of 11:124 syn-Indenofluorenone 11:124 from 1,2,4,5-benzenetetra carboxylate 11:124 lH-NMR of 11:124 Indicarol acetate 9:79,81,87 Indicine 1:269,270,325,326 synthesis of 1:270,325,326 Indicol 9:79,80,87 Indicoside A 15:61 fromAstropecten indicus 15:61 ~3C-NMR spectrum of 5:214 FAB mass spectrum of 5:214 ~H-NMR spectrum of 5:214 Indicoside B 5:215 Indicoside C 5:215 Indicosides A-C 7:299,301,302 from Astropecten indicus 7:299 Indicuminone 27:593 Indigo 1:20 reduction with hydrazine 1:20 Indigofera endecaphylla 19:117;27:522 Indigofera genera 27:519 Indigofera swaziensis 7:417
422
Indigofera tinctoria L. 22:523 for epilepsy 22:523 Indinavir 24:489 inhibitor of HIV- 1 protease 24:489 Indirect immunofluorescence 24:217 INDO MO method 18:981,985 Indobine 9:178 Indolalkylamines 9:510 Indole [2,3-a] carbazole alkaloid 5:55 Indole acetic acid 7:90,114 Indole alkaloids 1:31-34;2:172,173;5:3, 69-134,389,390,443,444 ;9:85, 163-199;13:70,92,93;10:407,411; 14:703-730 aspidosperma 13:70,92,93 Aspidosperma type 10:407,411 bisynthesis of 1:31-34 carbon 13 NMR of 9:165 CD of 2:172,173 Cotton effects in 2:172,173 hunteria 13:70,93 Hunteria type 10:407;13:70,93 identification of 9:163-199 mass spectroscopy of 9:165 synthesis of 14:703-730 thin layer chromatography of 9:164 UV spectroscopy of 9:164,173 Indole alkaloids 27:862;21:57,68,72,73, 84,107 Indole hallucinogens 25:531 psilocin 25:531 Indole N-tert-butyloxycarbonyl 3:309, 310 thermolytic deprotection 3:309, 310 Indole-2,3-quinodimethane 1:16,17 Indole-3-acetic acid 27:747 Indole-3-carboxaldehyde 21:240 Indole-3-pyruvic acid 12:374,375 biotransformation of 12:374 3-Indolecarbaldehyde 22:485 Indole-monoterpene alkaloids from Strychons dinklagei 6:503-522 from Strychnos species 6:503 of corynane strychnane series 6:503-520
Indoles 27:754 hydroxylation of 27:749,754 Indole synthesis 1:79,144,152 Fischer 1:79,144,152 Smith 1:360,365 Indoline derivatives 9:183-191 Indolizidine 9:72;21:56 2,3-Indolinone 22:79 (-)-(R)-Indolizidine 11:246-267;12:280 (+)-(S)-Indolizidine 12:280 (-)-Indolizidine 209D 16:489 synthesis of 16:489 Indolizidine 223A 27:242,243,287 GG-MS fragments of 27:242 Indolizidine 249H 27:243 structure of 27:244 Indolizidine 251M 27:242,243 mass spectrum of 27:243 Indolizidine 267J 27:242,243 5E,9E stereochemistry of 27:243 Indolizidine alkaloids 7:11-13,453-502; 25:190;27:233,235,236-238 1,4-disubstituted quinolizidines 27:238 3,5-disubstituted indolizidines 27:235,236 5,8-disubstituted indolizidines 27:235,238 from amphibians 27:234 from ants 27:234 pumiliotoxin alkaloids 27:238, 239 quinolizidine alkaloid 27:235, 236-238 spectral features of 27:236 structure identification of 27:240-247 structure identification of 27:247-249 structure of 27:233 synthesis of 1:360-365;10:556, 561;16:453-502 (+)/(-)Indolizidine alkaloids 11:246 absolute stereochemistry of 11:246 spectral data of 11:246,249,254, 255,11:264 synthesis of 11:246-267 asymmetric synthesis of 6:442,
423
443 in Solenopsis conjurata 6:450 synthesis of 6:442,443,445-451 (-)-( 1S, 2R, 8aS)-Indolizidine- 1,2-diol 12:303 configuration of 12:303 from Rhizoctonia leguminicola 12:303 (-)-swainsonine from 12:303 synthesis of 12:303-305 (1S,2R,8aR)-Indolizidine-1,2-diol 12:303,304 synthesis of 12:303,304 Indolizidine-7-one 19:33 Indolizidinediol 13:488 Indolizidines 19:25,32,38,45-46,48-51 synthesis of 19:42,32 enantioselective synthesis of 19:50 (-)-Indolizidines 205 A 16:479 synthesis of 16:479 (-)-Indolizidines 235B 16:479 synthesis of 16:479 Indolizidone 12:298 cross-aldolisation of 12:298 from L-proline thioester 12:297 (-)-Indolizomycin 12:301 absolute configuration of 12:301 antibiotic activity of 12:301 from Streptomyces grisline 12:300 from Streptomyces teryimanensis 12:300 reduction of 12:301 synthesis of 12:301-303 (+)-Indolizomycin 12:301-303 ;16:461 synthesis of 16:461 Indolo [2,3-a] carbazole alkaloids 12:365-409 biological activity of 12:384-399 synthesis of 12:375-383 Indolo [2,3-a] carbazoles 12:366,370 against Herpes simplex type 12:366,370 cytotoxic against human cancer ceU lines 12:370 from Nostoc sphaericum 12:366,370
Indolo [2,3-a] pyrido [a] quinolizine 3:404 1H-Indolo [2,3-a] pyrrolo [3,4-c] carbazole 12:365 Indolo [2,3-a] quinolizine 1:142,144, 153,155 synthesis of 1:142,144,153,155 Indolo [2,3-a] quinolizine alkaloids 8:288 synthesis of 1:123,159 Indolo-[2,3-a] quinolizidine 14:722-724 by alkaline decarboxylative cyclization 14:722-724 by Claisen rearrangement 14:722-724 preparation of 14:704-706, 720-724 Indoloazacyclodecane 14:862 Indoloazepine 14:831,832 14c~ and 14[3-hydroxyvincadifformine from 14:831,832 condensation of 14:831 epi-pandoline from 14:831 pandoline from 14:831,832 with 4-ethyl-4,5-epoxy pentanal 14:831 Indolocarbazole 21:263 Indolocarbazole alkaloids 1:6 biosynthesis of 1:6 Indoloquinolizidine 1:115,116;1:99, 100,712;15:497;25:4,28 Indoloquinolizidine aldehydes 1:111 Indoloquinolizidine enamines 14:727 preparation of 14:727 Indoloquinolizidine iminium salts 14:715-718 by Polonovski reaction 14:715-718 from indolo [2,3-ot] quinolizidine N b oxides 14:715-718 Indoloquinolizidine Nb-metho salts 14:718,719 preparation of 14:718,719 stereoselective 14:718,719 Indoloquinolizidine Nb-oxides 14:712 conformational equilibrium of 14:712 preparation of 14:711-714
424
stereoselective synthesis 14:711-714 3-Indolyl acetic acid 9:236 bis-Indolyl maleic anhydride 12:381 bis-Indolyl maleimides 12:365,372, 375-383 biological activity of 12:384-399 protein kinase activity of 12:389 1-[ 2-(3- Indo lyl) ethyl]- 3-methoxy carbonyl 1,4,5,6-tetrahydro pyridines 14:720 alkaline decarboalkoxylative cyclization of 14:720 indolo [2,3-a] quinolizidines from 14:720 2-(2-Indolyl)-propionic acid 9:236,237 3-Indolylacetaldehyde 11:288 2-Indolylacetaldehyde 11:315,316 from N-(p-MPS) indole 11:315, 316 preparation of 11:315,316 3-Indolyl-acetonitrile 11:281,282 Ritter reaction of 11:281,282 with (-)-13-pinene 11:281,282 Indolylmagnesium iodide 1:7 Indomethacin 7:397;20:514;25:56,58, 593,595,613,616;27:689,690;30:192 as cyclooxygenase enzyme (COX) inhibitor 30:192 Indo-pacific marine invertebrates 21:251 bioactive metabolites from 21:251 Induced skin tumor 29:76 by DMBA/fumonsin-B 1 29:76 by DMBA/mineral oil 29:76 by DMBA/okadaic acid 29:76 by DMBA/teleocidin B 29:76 by DMBA/TPA 29:76 by NOR-1/TPA 29:76 Inducible cyclooxygenase 25:47 inhibition of 25:47 Inducible nitric oxide synthase 25:47 inhibition of 25:47 Inductive action 23:579 of sonic hedgehog 23:579 Industrial applications 21:619 INEPT spectra 2:92,93 of 4-hydroxysapriparaquinone
5:36 of aquillochin 5:6 of artemisinin 5:27 of berberine 5:43,44 of colchicine 5:47 of damaran-20(S)-ol 2:92,93 of eupatorenone 5:30 of larreantin 5:10,11 of prionitin 5:31 of salvinolone 5:34,35 of sanguinarine 5:43 Infantile autism 30:376 hippocampal neurons in 30:376 Infantile convulsion 22:511,512,518, 519,521,535 Allium cepa L. for 22:511 Aneilema scapiflorum for 22:512 Arossostephium chinese L. for 22:518 Crossostephium chinese L. for 22:518 Desmodium pulchellum for 22:519 Ferula alliacea for 22:521 Ficus capensis for 22:521 role of HMG-CoA-Inhibitors in 22:250 Verbasum thapsus L. for 22:535 Infesting microorganisms 21:103 Infetroban 25:593 Inflammation 24:893-895;28:202; 30:192,224,225,732 COX-2 enzyme in 30:192 isoliquirtin in 24:893-895 pro-nociceptive prostaglandins in 30:192 role of free radicals in 30:224 role ofleukotrienes in 30:225 use of Artocarpus venenosa against 28:202 Inflammation mediators 30:225 leukotrienes as 30:225 Inflammatory activity 20:531 Inflammatory disorder 30:192 treament by COX-2 inhibitor 30:192 Inflammatory genes 30:319 COX-2 as 30:319 expression of 30:319
425 interleukin-2 as 30:319 interferon-), as 30:319 TNF-a as 30:319 Inflammatory pain 30:205,204 induction by formalin 30:205 inhibition by incarvillateine 30:204 Inflammatory skin condition 30:206 use ofbrein in 30:206 use of amyrin in 30:206 Inflexanin A 15:112,115 from Rabdosia inflexa 15:172 ~H-NMR of 15:122 Inflexanin B 15:112,117,124 from Rabdosia inflexa 15:172 IH-NMR of 15:124 Inflexarabdonin A 15:120 13C-NMR of 15:133 from Rabdosia inflexa 15:172 ~H-NMR of 15:126 Inflexarabdonin B 15:117 13C-NMR of 15:131 from Rabdosia inflexa 15:172 ~H-NMR of 15:124 Inflexarabdonin C 15:114 13C-NMR of 15:128 from Rabdosia inflexa 15:172 ~H-NMR of 15:121 Inflexarabdonin D 15:120 13C-NMR of 15:133 from Rabdosia inflexa 15:172 1H-NMR of 15:126 Inflexarabdonin E 15:115 13C-NMR of 15:129 from Rabdosia inflexa 15:172 1H-NMR of 15:122 Inflexarabdonin F 15:120 13C-NMR of 15:134 from Rabdosia inflexa 15:172 1H-NMR of 15:127 Inflexarabdonin G 15:115 13C-NMR of 15:129 from Rabdosia inflexa 15:172 ~H-NMR of 15:122 Inflexarabdonin H 15:115 13C-NMR of 15:129 from Rabdosia inflexa 15:172 ~H-NMR of 15:122
Inflexin 15:112,115 13C-NMR of 15:129 from Rabdosia inflexa 15:172 ~H-NMR of 15:122 Inflexinol 15:112,117 from Rabdosia inflexa 15:172 ~H-NMR of 15:124 Influence ofphytohormones 17:408,410 Influenza 30:407 therapy of 30:407 preventive medicines for 30:407 use of phytochemicals in 30:407 Influenza A treatment 27:108 role of amantadine 27:108 Influenza B 27:108 Influenza infection 27:103 Influenza virus 27:107,108;30:289,395, 407,408 enzyme mechanism of 27:114 in vitro 30:408 inhibitor of 30:395 representation of 27:107 Influenza virus replication 30:408 effect of sulphated polysaccharide (PS) 30:408 Infuscaside 2:280,281 Ingenane 12:233-245;25:243,246 synthesis of 12:233-245 Ingenane system 1:547 Ingenol 1:546,547,571;2:261;12:233245 IH-NMR of 12:234 synthesis of 1:547 synthesis of ring system 1:571 synthesis of 12:233-245 X-Ray crystallography of 12:234 Ingenol 20-hexadecanoate 29:103 activity in mam-2 bioassay system 29:103 Ingenol diterpenoids 17-hydroxyingenol-20-hexa-decanoate 25:543 ingenol-20-hexadecanoate 25:543 Ingenol type diterpenes 24:288 anti-tumor activity of 24:288 Ingol 2:261 Inhibitins 7:119 of aminoglycopyranoses 7:47
426
of 1 thio fI-D-galactopyranosides 7:48 Inhibition 7:47,48;9:581;23:239; 25:45-46,66,313,331,344,477,512, 615 of 4-(methylnitrosamino)-l-(3pyridyl)- 1-butanone (NNK) induced lung tumors 25:46 of 5-1ipoxygenase 25:47 of 12-1ipoxygenase 25:47 of 15-1ipoxygenase 25:47 ofadenylyl cyclase 25:532 of adjurant induced polyarthritis 25:46 of arachidonic acid 25:66 of arachidonic acid induced edema 25:46 offl-hematin aggregation 25:342,354 of bradykinin induced edema 25:46 of capsaicin induced edema 25:46 of carrageenan induced edema 25:46 of cotton pellet granuloma 25:46 of cycloxygenase 25:47 of Epstein-Barr virus early 25:46 of eukaryate signal transduction components 25:512 of falcipain 25:331 of heme polymerizations 25:348 of heme sequestration 25:348 of hemozoin 25:354 of histamine release 25:47 ofhepatocyte apoptosis 25:477 of human leucocyte elastase 25:47 of hylauronidase 25:47 of inducible cyclooxygenase 25:47 of inducible nitric oxide synthase 25:47 of DMBA/TPA induced skin tumor 25:48 of LDL oxidation 25:946 of lyso PAP acetyltransferase activity 25:615 4-( me thylni trosamino)- 1-(3-
pyridyl)- 1-butanone (NNK) induced lung tumors 25:46 of pisatin 12:399 of protein kinase C 23:239 Inhibition, of LTCa-release 27:691 Inhibition, of PGE2-release 27:690 from peritoneal macrophages 27:690 Inhibitor 23:68;24:1085;25:542,544, 546;30:836 of 1AA oxidation 25:657 of calmodulin 25:706 of CDPK 25:542,546 of cell adhesion 24:1085 of EFEs 30:836 of enzymes 9:515 of gram-positive bacteria 23:68 of human synovial PLA2 25:697 ofkinesin motors 25:695 of PKA 25:541 of PMA 25:938 of protein phosphatases 25:707 ofsterol biosynthesis 25:303 of vitamin-D-metobolism 9:515 offl-hemetin 25:357 Inhibitory action 27:402 of chitosan 27:402 Inhibitory activity 12:332;21:98,193, 263,270,312,398,430,585,589,591, 594,643,659,670, 673,675,690 ;23:59, 216,808;26:217;28:481 ;30:629 against bone resorption 21:720, 721 against H§247 21:719 against Staphyllococcus aureus 30:629 mechanism of action of 30:225 of (-)-(8,Sa-di-epi-swainsonine 12:325 of (-)-swainsonine 12:327 of (+)-castanospermine 12:332 of benzalmalonates 9:225-227 of honokiol 26:217 of inumakilactone A 28:481 of inumakilactone/3 28:481 of inumakilactone C 28:481 of machilin A 26:217 of matairesinol 26:217 of mitogen-induced arctigenin
427 26:217 of nagilactone A 28:481 ofnagilactone B 28:481 ofnagilactone C 28:481 ofpodolactone A 28:481 ofpodolactone B 28:481 ofpodolactone C 28:481 ofpodolactone D 28:481 ofpodolactone E 28:481 of rifamycine-type ansamycine antibiotics 23:59 of taurospongin A 23:216 on blastogensis 26:217 Inhibitory activity, against human epidermoid carcinoma 24:848 Inhibitory effect 21:695,701,719; 23:311-316,318,445,673,721; 24:215-264,849;25:55 ;27:437; 30:396,594,801 ofcelafoin C-1 23:673 ofcelafolin D-2 23:673 in vitro 30:396 of ailanthone 23:318 ofailantinol A 23:315 ofalienanin B 23:445 of amarolide 23:315,318 ofbrucein D 23:312 ofbudlejasaponin IV 27:689, 690,691 of carp extract 27:440,689 ofcelafolins B-2 23:673 ofcelafolins C-1 23:673 ofcelafolins D-2 23:673 on chemical carcinogenesis 24:215-264 of chitosan 27:437,440 of curcumine 23:316 of DAGO 30:801 of dermorphin 30:801 of dihydroagarofuran sesquiterpenes 23:673 of flavonoids 24:215-264 of ginseng saponins 27:423 of H+,K+-ATPase 21:701,719 ofHernandia sp. 30:594 ofmaytansinoids 23:721 of morphine 30:801 of natural quassinoids 23:311 ofneoquassin 23:314,318
ofnigakihemiacetal D 23:318 ofnigakilactone F 23:313 of picrasin B 23:313 ofrotenoids 24:215-264 ofsandrosaponin I 27:689,690, 691,693 of SDB 21:695 of semi-synthetic quassinoid 23:311,319 of shinjudilactone 23:318 of shinjulactone A 23:315 of steroids 24:215-264 oftriptofordin F-2 23:673 oftriptogelin A-1 23:673 oftriterpenoids 24:215-264 ofyadanziolide C 23:312 of ~t-agonists 30:801 on bone resorption 21:702 on croton oil-induced inflammatory edema 25:55 on Epstein-Barr virus activation 24:849 on gastric acid secretion 21:701 on H+,K+-ATPase 21:701 on HHPA 25:55 on HIV replication 30:396 on HSV-1 replication 21:695 on TPA 25:55 Inhibitory mechanisms 30:318 of emodine 30:318 Inhoffen-Lythgoe diol 1:591,592 synthesis of 1:592 I-nitropyrene (I-NP) 22:623,624 Injection techniques 9:457 Inlet systems 2:45 Innzeylanine 26:850 INOC reaction 1:480,481 Inones 25:125 Inosine (x-L-fucopyranoside-H 23:199 Inosine H 23:199 Inosine monophosphate 22:259 myo-Inositol 7:181;13:190;18:391; 19:352-353 D-chiro-Inositol 18:439 Inositol (cyclohexanhexaol) 7:37 myo-Inositol 1-phosphate 11:216,217 by myo-inositol- 1-phosphate synthase 11:216,217
428
from glucose-6-phosphate 11:216,217 L-chiro-Inositol 2,3,5-trisphosphate 18:416 Inositol lipids 22:21 Inositol phosphates 18:393-451 Myo-Inositol triflates 18:439 Inositol triphosphate 22:666 Inositol triphosphate (IP3) 25:483,487, 488,509,524 radioactive 25:487 Inositol- 1,4,5-triphosphate 22:21 Inositol- 1,4,5-triphosphate (IP3) 25:522, 547,548 Myo-Inositol- 1-phosphate synthase 11:216 from beef testes 11:216 from Lilium longifolium 11:216 myo-mositol 1-phosphate by 11:216,217 Inostamycin 15:453-456,461 Inouye's photochemical route 12:198 Inqayi 23:656 Insect antifeedant activity 23:319 of natural quassinoids 23:319 of semi-synthetic quassinoid 23:319 Insect cell-based bioassays 29:30 cyasterone activity in 29:32 2-deoxy-20-hyroxyecdysone activity in 29:32 14-deoxymuristerone A activity in 29:32 2 [3,3[3-dihydroxy- 5 [3-cholest-7en-6-one activity in 29:32 3 [3,14cx-dihydroxy-5 [~-cholest-7en-6-one activity in 29:32 ecdysone activity in 29:32 3 [3-hydroxy-5 [3-cholest-6-one activity in 29:32 20-hydroxyecdysone activity in 29:32 inokosterone activity in 29:32 Kc cell bioassay as 29:30 makisterone A activity in 29:32 muristerone A activity in 29:32 podecdysone A activity in 29:32 ponasterones activity in 29:32
213,3[3,5[3,14cx-tetrahydroxycholest-7-en-6-one activity in 29:32 2[3,3[3,25-tridihydroxy-5 [3cholest-6-one activity in 29:32 viticosterone E activity in 29:32 Insect control 21:611 Insect juvenile hormone analogues 14:395-397 from thujone 14:391-397 synthesis of 14:391-397 via [3-1actone route 14:395-397 Insect neuropeptides 9:487-493 Insect pheromones 11:415-417 via diisopropylethanediol esters 11:415-417 via pinanediol esters 11:412-414 synthesis of 3:270-273,493,494; 11:412-417 Insect repellant 5:757 Insecticidal activity 18:229,704;21:252, 254,262,266,267,269,270,271,278, 285,379,595,611 ;23:666;667,670, 677,678;24:25,799,845,866;26:231, 232,426,471,479,485;28:477; 30:153-154,695 biological activity 24:25,799,845 bioassay of 24:866 of 14-epi-ponolactone A 28:477 of anacardic acid 30:153-154 of celastrus angulatus 23:666 ofhallactone A 28:477 ofhallactone B 28:477 of lemon juice phenolics 23:748 oflollo rosso 23:759 ofnagilactone A 28:477 ofnagilactone C 28:477 ofnagilactone D 28:477 ofnagilactone E 28:477 ofpodolactone A 28:477 ofpodolactone C 28:477 ofpodolide 28:477 of quinone methides 30:695 of red lettuce anthocyanins 23:760 of red onion anthocyanins 23:762 of Romaine lettuce phenols
429
23:761 ofsellowin A 28:477 of sesquiterpene alkaloids 23:678 of sesquiterpenes 23:667,670 Insecticidal assay 21:273,276,281,284 Insecticidal effects 26:852,1136 of ryanodol-type diterpenes 26:852 of isoryanodol-type diterpenes 26:852 Insecticidal properties 21:225 Insecticidal sesquiterpenes 23:668 from Euonymus bungeanus 23:668 Insecticidal Stemona alkaloids 21:759 Insecticides 7:395-397;21:110;28:390 used of essential oil 28:415,390 Insect-plant relationship 27:384 Insomula 21:101 Insositol- 1,4,5-triphosphate (IP3) receptor 25:534 Insularoside 26:321-323,325,327,333, 343 Insulin 2:25 bovine 2:23-25 gene synthesis 4:271 isotopic distribution of (MMH +) 2:25 Insulin B chain 2:23-25;25:390 Insulin signalling activated protein kinase 25:522 Insulin-responsive protein kinase (PKB) 25:517 Integerrimine 1:272-274 synthesis of 1:272-274 Integerrinecic acid 1:263-267 synthesis of 1:263,264,266,267 Integramycin 28:147 as HIV-integrase inhibitor 28:147 Integrase 30:226 cleaveage of 30:226 role in HIV 30:226 Integrins 27:825 Inter alia 26:481 Interaction of THS 25:468 with a-TNF 25:468 Interconversion 27:336 of abscisic acid ring 27:336,338
Interferon 4:273;25:519 LPS induction of 4:199 Interferon gamma (IFN-~,) 30:689 inhibitory effect on 30:689 production of 30:689 Interferon production 12:390 by human cell cultures 12:390 protein kinase in 12:390 Interferon 3' (IFN-?,) 25:431,464,477; 26:951 Interferones (INFs) 24:489 Interferon-ct-[3 and y 20:531-533;26:951 Interiotherin A 26:197,223,224 Interiotherin B 26:197 Interleukin 25:271,540;26:951 Interleukin I 5:388 Interleukin I induction 4:197 by LPS 4:197 Interleukin-1 22:110;30:689 by synovium 30:689 production of 30:689 Interleukin-2 25:536 Interleukin-2-dependent (IL-2) 25:271 Interleukin-6 cytokine family 25:717 Interleukin-8 25:711 (+)-Intermedeol 14:449-451 biological activity of 14:450,451 from ot-agarofuran 14:453 from Bothriochloa bladhi 14:450 from Bothriochloa glabra 14:450 from Bothriochloa intermedia 14:449-451 from Bothriochloa insculpta 14:450 from Carthamus lanatus 14:450,451 from Citrus paradisi 14:450 from Cymbopogon flexuosus 14:450,451 from (-)-7-epi-cyperone 14:452, 453 from Senecio amplexicaulus 14:450 from Velocitermes velox 14:451, 452 synthesis of 14:456-465 total synthesis of 14:452,453
430 (+)-Intermedeol 14:450,451;23:800 biological activity of 14:450,451 Intermedine 1:269 Intermedine N-oxide 1:270 Intermolecular additions 24:201 Intermolecular aldol condensation 10:318-320 Intermolecular cationic [5+2] cycloaddition 8:160,161 Intermolecular cyclization 6:59 spirosystems construction by 6:59 Intermolecular Diels-Alder cycloadditions 24:33 Intermolecular Diels-Alder reaction 6:549,550;24:768 Intermolecular Knoevenagel type cyclization 24:33-40 Intermolecular Michael reaction 14:552 enantioselective 14:552 Intermolecular O-alkylation 8:198,199 Internal aldolization 6:81 in (+)-2-isocyanopupukeanane synthesis 6:81 Internal alkylation 6:74 in (+)-9-isocyanopupukeanane synthesis 6:80 Internal Diels-Alder reaction 6:86,87 International council of harmonization 27:304 Internuclear distance 2:60,61 and cross-relaxation rates 2:60, 61 from NOE rations 2:61 Interproton distances 2:70,71 Intersystem crossing 22:214 Intestinal calcium transport 30:484,497 assay for 30:497 of lot,25(OH)2D3 30:497 role of vitamin D2 in 30:484 Intestinal diseases 30:224 role of free radicals in 30:224 Intestinal worms 1:435 Intraerythrocytic antimalarial activity 25:343 Intraerythrocytic cycle 25:329 Intraerythrocytic phase 25:327,328,329 Intramolecular [2+1 ] cycloaddition 6:52
Intramolecular [2+2] cycloaddition 12:193 Intramolecular [2+2] photoaddition 12:210 Intramolecular [2+2] photocycloaddition 6:69 Intramolecular [4+ 1] pyrroline annulation 1:250 Intramolecular [4+2] cycloaddition 6:85 in (+)-sinularene synthesis 6:85 in 7,20-diisocyanoadociane synthesis 6:86,87 olefin tropolone 5:799 Intramolecular 1,3-dipolar cycloaddition 12:318 Intramolecular acetalization 14:60 Intramolecular acylinitroso Diels-Alder reaction 1:386 Intramolecular addition 10:3-11 to chiral sulfoximines 10:3-11 to chiral vinyl sulfoxides 10:3-11 Intramolecular Alder ene reaction 10:222,224 Intramolecular aldol condensation 6:549,550,231 ;15:235,269,297; 24:779,780 Intramolecular aldol cyclization 6:36, 66,67;18:633 in poitediol synthesis 6:36 in (-)-upial synthesis 6:66,77 Intramolecular aldol reaction 24:15,24, 25;26:111 Intramolecular alkylation 6:42,43; 8:225-233,540,558;24:13 Intramolecular amidoalkylation 1:246 Intramolecular aminomercuration 10:532,540;12:333 Intramolecular arylation 12:447-452 Intramolecular base-induced rearrangement 14:374 Intramolecular C-alkyation 24:9-11 Intramolecular carbenoid displacement 1:259 Intramolecular carbocyclization 24:15 Intramolecular chelation 14:53 Intramolecular Claisen condensation 18:299 Intramolecular coupling 6:546,547
431 Intramolecular cyclization 2:282; 21:36,37,398 nickel-catalyzed 2:282 spirosystems construction by 6:59 in (+)-9-isocyanopupukeanane synthesis 6:82,83 Intramolecular cycloalkylation 6:6; 24:9,10 in (+)-amjitrienol synthesis 6:53 in tricyclic natural products synthesis 6:74 Intramolecular cyclopropanation 6:73, 74 Intramolecular Diels-Alder reaction 4:601,602 betaenone B by 4:601,602 coronafacic acid by 4:596,597 diplodiatoxin by 4:600-602 endo rule 4:18 fused versus bridged product 4:565 in biosynthesis 4:616,621 kinetic selectivity 4:601 solanapyrone A by 4:598 stereoselectivity 4:595,596 Intramolecular displacement reaction 12:311,344 Intramolecular diyl trapping reaction 6:46 Intramolecular double Michael addition 8:418 Intramolecular ene reaction 24:29,30, 759,760 Intramolecular glycosylation 14:236 Intramolecular heteroene reaction 12:295 Intramolecular Homer-Emmons condensation 12:341 Intramolecular Homer-Emmons reaction 24:15 Intramolecular Michael addition 6:70, 71 in (+)-sanadaol ([3-crenutal) synthesis 6:70,71 Intramolecular Michael cyclization 14:552 of an acyclic compound 14:552
Intramolecular Michael reaction 6:178, 184,196 asymmetric 14:551-567 by chiral enamine 14:551-567 enantioselective 14:551-567 Intramolecular oxidative coupling 6:480 Intramolecular photocycloaddition 6:34, 35,54 in (+)-epi-precapnelladiene synthesis 6:34,35 in isoamijiol synthesis 6:54 Intramolecular Pinner reaction 15:415 Intramolecular Prins reaction 24:64,65 Intramolecular radical-induced carbocyclization 24:15-18 Intramolecular reaction 11:45-47 (2+2) cycloaddition 11:45-47 [4+4] cycloaddition 11:17 1,3-dipolar cycloaddition 11:283-285 aldehyde-ketophosphonate condensation 6:264,265 aldol condensation 11:90,108, 113,115;12:82 alkylation of 8:176,177 amidoalkylation 10:108 amidomercuration 12:281 aminolysis 12:279 annulation 10:407 asymmetric hydrosilylation 13:72 azido-olefin cyclization 13:447, 448 Biellmann coupling 10:6-10 C-C bond formation 12:65 cross-coupling reaction 10:163 cross-aldolisation 12:289 cyclization 10:631-633;12:281, 327 dicarbonyl coupling 11:345, 364-367 Diels-Alder reaction 10:51,52, 155,409;11:11,92,93,99,108; 13:108-115;14:745 double cyclization 10:83 displacement 12:347 ene reaction 11:91-108 epoxide alkylation 14:746 esterification of 8:176
432
etherification 12:65 Friedal-Crafts acylation 10:131 Friedal-Crafts reaction 10:312, 313 hetero Diels-Alder reaction 6:449 Horner-Emmons condensation 10:13-17 imino Diels-Alder approach 14:732,733 Michael addition 11:312;14:736 Michael reaction 9:435,437; 10:51,52;13:180-443 mixed Claisen condensation 12:104 Mukaiyama condensation 10:181,182 N-acyliminium ion cyclization 11:284,285 nitrile oxide cyclization 14:745 nitrone cycloaddition 14:744 O-C bond formation 12:83 P ~-allyl Pd alkylation 10:10-13 photocycloaddition 11:20 photoreduction 12:283 proton transfer 12:102 Pummerer reaction 10:682 rhodium II mediated 10:407 ring contraction 11:42,43 ring-opening 12:83 Sakurai reaction 10:182 S-alkylation 13:145 SE' additions 10:17-25 SN2 cyclization 12:85 SN'-process 11:323 stereoselective cyclization 10:92 translactonization 13:159 trans-sulfenylation 12:69,72 Ulmann reaction 10:640 Wadsworth-Emmons reaction 12:328 Wittig Homer reaction 11:152, 153 Wittig reaction 13:601 Wittig-Horner cyclization 12:292 Wittig-type reaction 12:147 cz-diazo-13-keto ester synthesis 10:407
Intramolecular reduction 14:153 Intramolecular reductive amination 12:316 Intramolecular reductive coupling 6:48, 52,54 in (-4-)-A9(12) capnellene synthesis 6:48 in dolasta-1 (15),7,9-trien-14-ol synthesis 6:52 in isoamijiol synthesis 6:54 Intramolecular ring closure reaction 6:492 Intramolecular trans-ketalization 10:211 Intramolecular type I-"Mg-ene" reaction 6:45,46,76-78 in (+)-A 9(12) capnellene synthesis 6:45,46 in (+)-sinularene synthesis 6:76,77 Intramolecular vinylogous aldol reaction 24:14,22,23 Intramolecular Wittig reaction 1:234, 235,573 Intramolecular rt-alkylation 6:184,185 Intrapetacin A 28:66 anti-fungal activity of 28:66 Intrapetacin B 28:66 anti-fungal activity of 28:66 Intrasinusoidal hematosis 25:464 Intrinsic activity 30:596,816 in vivo 30:596 of alkaloids 30:596 of central opioid receptors 30:816 of DER 30:816 of glycopeptides 30:816 Introns 13:290 Inula britannica 29:90 lnula cappa 5:678 Inula crithmoides 5:728 Inula nervosa 19:125 Inula viscose 29:87 Inuviscolide 29:90 activity in TPA assay system 29:90 Inverse electron demand 4:579,580,604 in Diels-Alder reaction 4:579,
433
580,604 using enamines 4:604 using enols 4:604 using ketone dithioacetal 4:604 Inversion 1:459 of alcohol center 1:204,205,456, 457,459 Mitsunobu protocol 1:459 Invertase inhibition 21:593 Invictolide 1:681-683;3:272,273 ent-Invictolide 16:711-712 synthesis of 16:711-712 Iodination 27:751 oftyrosine 27:751 Iodine pentoxide 1:51 oxidation of indoles to acylindoles 1:151 Iodine-catalyzed 6:139-141,153,154 stereomutation mixtures 6:139-141,154 isomerization 6:141,153,154 5-Iodo ketones 8:245 4'-Iodo-4'-desoxydoxorubicin 14:21 w-I o do alkyl-2-phenylthiomethyl-4,6dimethoxy-benzoate 8:176,177 p-Iodoanilide 23:55 Iodobenzene diacetate 4:331 c~-hydroxylation of ketones 4:331 Iodocarbonate 11:361 enantiomerically pure oil from 11:346,347 with p-toluene sulfonic acid monohydrates 11:346,347 8-Iodocoumarin 4:372 Iodocoumarin 4:396,398 with copper acetylide 4:396,398 Iodocyclisation 10:391 of alkene 10:391 Iodocyclocarbamation 4:126 Iodoetherification 10:21,24 Iodolactone 8:153,154 Iodolactonization 1: 199,204-206, 254,526;13:208,622 by m-chloroperbenzoic acid 11:358,359 by iodine 11:358,359 Iodomagnesium salt 14:750
Iodomethylphenyl sulfide 4:463 alkylation with 4:462 5-Iodopentadienoic acid 21:393 p-Iodophenyl 4-O-triflygalactopyranosylglucoside 8:343,345 D-Iodopyranoside 19:367 Iodosobenzene 14:780 N-Iodosuccinimide 26:1162 Iodosulfonation 21:384 Iodotrimethyl silane 1:390;11:528 cyclization with 11:109 Iodotyrosine 23:241 125I-Iodotyrosine 25:373 Ion channel blockers 22:16 Ion channels 21:73,98 alkaloids with 21:3-111 Ion gradient generating ATPase 25:512 Ion-channel complex 21:18 Ion-exchange column chromatography 19:519 Ionic cycloaddition 5:793 Ionization energy 2:3 Ionoization behaviour 21:556 of procyanides 21:556 (+)-Ionomycin 16:715-716 synthesis of 16:715-716 Ionomycin 3:58 ~-Ionone 13:328,330;20:576,584; 28:406 acaricidal properties of 28:406 [3-Ionone 17:612 ~-Ionone 20:589 (R)-(+)-ct-Ionones 20:584 Ionophone A23189 25:274,275,940 Ionophore 3:273-277;21:414;25:374 synthesis of 3:273-277 Ionophore activity 4:93;18:857 Ionophore X-14547 A 10:425 synthesis of 10:425 Ionophores 16:711 Ionophoric antibiotics 21:303 IP3-Ionositol-l,4,5-triphosphate 25:516 Ionotropic glutamate receptors 25:528 Ionotropic serotonin receptors 25:529 Ionotropic receptor 25:528;30:192,193 heat-activated channel TRPVI type 30:193 role in nociceptor depolarisation
434
30:192 role in tetrodotoxin-resistant sodium channels 30:193 role in vanilloid receptors 30:193 TRPM8 type of 30:193 "Ionoxide" principal 14:424,425 Iophotoxins 18:697,698 IP3 receptors Ca 2+ channel 25:534 IPa-gated Ca 2+channels 25:517 IPa-induced release of Ca 2+ 25:488 IPa-Inositol- 1,4,5-triphosphate 25:516 Ipalbidine 1:283,293,363-365 synthesis of 1:283,293,363-365 Ipalbine 1:362 Ipc2BC1 8:476 as chiral reducing agent 8:476 IpcBH2 8:475,476 as chiral reducing agent 8:475, 476 Ipecacuanha alkaloids 7:444,92 Ipolamiide 7:458,459,463;29:84 activity in CRG, BRK, HST assay systems 29:84 Ipolamiidol 7:467 (+)-Ipomeamarone 15:236,237 Ipomeamarone 15:249 biosynthesis of 15:249 synthesis of 3:57-58 (-)-Ipomearone 15:237 Ipomine 1:362 Ipomoea 2:369 tissue cultures of 2:369 Ipomoea alba 1:362 alkaloids of 1:362 Ipomoea batatas 29:604 lpomoea cairica 26:223 Ipomoea hederaceae L. 22:523 for epilepsy 22:523 Ipomoea hispida 22:523 for epilepsy 22:523 Ipomoea muricata 1:362 Ipomopsis aggregata 23:96 lponuga 27:250 IPP-DMAPP isomerase 7:108,109 Ipratropium 22:738 S-(+)-Ipsdienol 16:242 Ipsenol 1O: 188 synthesis of 10:188 Ipstypographus 27:384,385
IR spectrum 27:177 of sanguilutine free base 27:177 Ircenals 24:573,615,667,669 anti-bacterial activity of 24:573 anti-leukemic activity of 24:573 Ircinia dendroides 25:885;28:684 lrcinia fasiculata 28:673 fasiculatin for 28:673 Ircinia sp. 21:260;25:688,703,705,709; 28:670,714 Ircinia spinulosa 28:676;29:694 brine shrimp toxicity of 28:676 2-prenylhydroquinones of 28:676 Ircinia sponges 25:695 Ircinia variabilis 28:673 22-O-sulfates of palinurin from 28:673 sulfate esters from 28:673 Ircinia wistarii 6:8 ircinianin from 6:8 wistarin from 6:8 Ircinianin 4:618,619 biosynthesis of 4:618,619 from Ircinia wistarii 6:8 from methyl g-oxosenecioate 6:8 synthesis of 6:8 Irciniasulfonic acid 28:714 reverses multidrug resistance 28:714 Ircinin 25:688 (-)-Ireland alcohol 14:119,120 synthesis of 14:119,120 Ireland approach 12:16,17 Ireland-Claisen rearrangement 3:268, 614;10:416,417,424-425,429;18:230, 231,259;20:67,1227 in nonactic acid synthesis 3:228 Kazmaier's modification of 26:1227 ofallylic glycolate esters 10:437 ofsilyl ketene acetal 10:423 Iridium black 6:83,85 selective hydrogenation with 6:83,85 Iridium complexes 21:386 Iridodial 7:441,442 Iridodiols 7:442,482 Iridoid boschnialactone 8:133
435
Iridoid glucoside 6:529,114,439,440, 445,457;7:461,469,472,475 chemistry of 7:455-486 classification 7:454,455 nomenclature 7:451,452 structural characteristics 7:453, 454 Iridoid precursor 6:503,529 Iridoids 7:439-492;24:799,510-521 13C-NMR spectrum of 7:486,487 diuretic activity of 7:490 IH-NMR spectrum of 7:486,487 4-hydroxymethyl-substituted iridoids 7:467 5-hydroxy-substituted iridoids 7:463,464 acid catalysed transformations 7:456-468 acid hydrolysis of 7:462 aglycone 7:458,461,465,486 analgesic activity of 7:490 antidote for ot-amanitin poisoning 7:490 antileukemic activity of 7:490 antiphlogistic activity of 7:490 antitumor activity of 7:490 as chiral templates 7:468 biogenesis of 7:488,489 biological activity of 7:490 bisiridoids 7:443 chemistry of 7:439-492 choleretic activity of 7:490 chromatography of 7:488 definition of 7:439 diuretic activity of 7:490 gentiopicroside type 7:443 glycosides 7:439,457,461,468, 469,472,475 glycosylation of 7:488 hypotensive activity of 7:490 trifluoromethane-sulfonate (TMS-triflate) 7:488 hepatoprotectivity of 7:490 interconversion of 7:469 iridodiols 7:442 laxative activity of 7:490 miscellaneous-type 7:442 NaBH4 reduction of 7:466 oleuropein type 7:443
partial synthesis of 7:478-486 plumeria-type 7:442 secoiridoids 7:442,443 secologanin type 7:443 sedative activity of 7:490 simple 7:440,441 stability of dihydropyranic ring 7:455 synthesis of 7:487,488; 16:289-320 uterine contracting activity of 7:490 valeriana-type 7:442 Iridolactam alkaloids 6:503,529 Iridolactam derivatives 6:522-527 Iridomyrmecin 7:441,442;16:289; 20:70,74 Iridomyrmecin derivatives 7:476,477 Iridomyrmex humilis 5:223,225,240, 241,245,253 Iridomyrmex nitidus 5:222-224,233,253 Iridomyrmex purpureus 5:222,224,233, 253 Iridomyrmex rufoniger sp.gr. 5:223, 237,253 Irilin A 22:473 Irilin B 22:473 Irilin C 22:473 Iris germinica 10:152 Iris japonica 26:433 Iron pentacarbonyl 14:689,690 Iron responsive element 26:951 Iron tricarbonyl derivatives 1:572 acylation of 1:572 oftropone 1:572 [3-Irone 10:152 lrpex lacteus 26:439,468 Irreversible cytotoxicity 15:447 Irreversible inhibitors (suicide substrates) 7:36-40 Irritable bowel syndrome 30:368 role of serotonin (5-HT) 30:368 Irritant terpenoids 2:287 from liversorts 2:287 Irumamycin 5:467-471 Irumanolide I 5:599 Irumanolide II 5:599 Iryanthera lancifolia 22:356 dihydrochalcones from 22:356
436
flavonolignoids from 22:356 tocotrienols from 22:356 Iryanthera sagotiana 22:355 Isatis tinctoria 26:632 Ischaemia reperfusion 22:438;25:61 O, 614 (+_)-ent-Iscoent-Isocopal-12-ene- 15,16dial 6:119-122 synthesis of 6:119-122 ISCOMs 21:648,650 Ismine 20:356,369 Iso- 1-cytochrome 18:915,916 Iso-l-cytochrome C 18:832,838 Iso-6-canavaline 20:486 Iso-6-cassine synthesis 29:419 by stereodivergent process 29:419 Isoacronycine (pyrano[3,2-b] acridin-6one) dervatives 13:348,356 E-Isoafrol 8:160 Isoagatholactone 1:56,57,107,108,662 synthesis of 1:662 from (+)-labda-8(20), 13-diene15-oic acid 6:65,57 from Spongia officinalis 6:56, 107 (+)-Isoagatholactone 6:56,57 from (+)-Isoagatholactone 6:56, 57 from ent-methyl isocopolate 6:56,57 synthesis of 6:56,57 (-)-Isoagatholactone 6:57 synthesis of 6:57 Isoagatmic acid 6:107,108 S-Isoajmalicine 9:171 Isoajmaline 9:183,185,403 Isoalatol 18:745 (+)-Iso-allamandicin 16:301 synthesis of 16:301 Isoalliin 23:458,461 Isoalvaxanthone 28:230 biological activity of 28:230 (+)-Iso-Ambrox 14:420-425 synthesis of 14:420-425 Isoamericanol A 26:270 Isoamijiol 6:53,54 Isoampelopsin F 26:568 Isoamyl acetate 25:129
Isoamylases 10:498 Isoanacardic acid 9:371 Isoanacardic aldehyde 9:370 Isoannonacin- 10-one 17:270 Isoantibodies 29:542 antigen of 29:542 synthesis of 29:542 (+)-Isoaplysin-20 1:663,664 synthesis of 1:663,664 Isoaplysin-20 6:56 (_)-Isoaplysin-20 6:56,57 Isoaquillochin diacetate 5:7,8 Isoarcapillin 227 Isoastragaloside I 25:193 Isoavenaciolide 19:485 synthesis of 3:260,261 Isobaccharin 30:737 structure of 30:737 Isobaccharinol 30:736 structure of 30:736 Isobacteriochlorins 9:591,597,604 Isobalchanolide 7:231 Isobatzeiline A 25:822,790 Isobatzelline B 25:822,790 Isobatzeiline D 25:822 Isobazellines 25:707 Isobergapten 22:539 Isobetanidine 20:724,731 (+)-Isoboldine 16:509,512 Isoboldine 18:58 Isobonafousine 5:128 Isoborneol 25:154 (+)-Isobornyl acetate 4:645,646 remote oxidation of 4:645,646 Isobrafouedine 6:172 biosynthesis of 6:521 spectral data of 6:403-506 from Strychmos dinklagei 6:503 Isobrucein 5:38-41 Isobrucein-A 7:396,397,72;23:304 Isobrucein-B 7:374,381;23:285,304,313 Isobrucine 26:1051,1052 Isobrucine-N-oxide 26:1051,1052 Isobrugierol 7:193,194 8~-Isobutycyloxyestafafin 27:578 Isobutyl (2E,4E)-2,4,8-nonatrienamide 10:151 Isobutyl (2E,4E, 8Z)-2,4,8-decatrienamide 10:151
437 Isobutyl (2E,4E,8Z)-2,4,8-eicosatrienamide 10:151 Isobutyl (2E,4E,8Z, 10E)-2,4,8,10dodecatetraenamide 10:152 Isobutyl chloroformate 22:281 Isobutylamides 21:378 Isobutylamine 21:378 Isobutyl-methoxy pyrazine 13:320 Iosobutylmethylxanthine 25:275 6-Isobutyloxycarbonyl derivative 25:829 Isobutyrate 11:197 in Streptomyces cinnamonensis 11:197 monensin A with 11:197 [1-13C] Isobutyrate 5:608 Isobutyric acid 22:210 N-Isobutyrolycycloxobuxine 2:205 N-Isobutyroylcycloxobuxidine-H 2:205 Isobutyryl CoA 11:197 in Streptomyces cinnamonensis 11:197 interconversion of 11:197 stereochemical 11:197 Isocajucarinolide 29:100 activity in TLO assay system 29:100 (23R)-23H-Isocalysterol 9:38 (24S)-24H-Isocalysterol 9:38,44,45 (23S)-23H-Isocalysterol 9:38,45 from Calyx podatypa 9:38 2-Isocaproyl-3R-hydroxymethyl-),butyro lactone 18:700 Isocarbacyclin 1:639-641 enantioselective synthesis of 1:639-641 synthesis of 14:509 (+)-Isocarbacyclin 6:315 synthesis of 6:315 preparation of 16:388 Isocarotene 30:544 (+)-Isocorydine 30:564 5,6-dimethoxy-n-methylphthalimide 30:563 Isocaryophyllene 3:73,74,84-89 synthesis of 3:73,74,84-89 6-Isocassine 9:50,53 Isocedranes 13:41 Isocedranol 15:270
5-Isocedranone 5:791,792 Isocedrene 13:46 6-Isocedrol 5:789 Isocelorbicol 18:743 2-Isocephems 12:126 antibiotic activity of 12:126 Isochiloscyphone 18:614 Isochlorogenic acid 22:346;23:740 Isochlorogenic acid 'a' 23:744 Isochlorogenic acid 'b' 23:744 Isochlorogenic acid 'c' 23:744 Isochromazonarol 15:299 Isochromophilones 25:797 (2R,3S)-Isocitrate 20:872 Isococculidine 25:528 Isocodonocarpine 9:53,54,57 epi-Isocomene 3:41 [3-Isocomene 3:6,20 Isocomene 3:6,9,15,21,24,60;13:4-6 synthesis of 3:6,9,15,21,24,60 ISOCOMS (Immunostimulating complexes) 24:163 (+)-Isoconcinndiol 6:26 from Laurencia snyderae 6:26 (+)-14-epi-Isocopal- 12-ene- 15,16-dial 6:108,110 (+)-ent-Isocopal- 12-ene- 15,16-dial 6:108,110 (+)-14-epi-ent-Isocopal- 12-ene- 15,16dial 6:111,119,122 synthesis of 6:119-112 ent-Isocopalane 6:108 Isocopalane-type diterpenes 6:119-122 (+)-Isocorynoline 14:785-789 from corysamine 14:785-789 oxidation of 14:785-789 synthesis of 14:785-789 through enamine-aldehyde cyclization 14:785-788 Isocoumarins 7:266,267,270,287; 20:283;23:343 Isocrepidamine 12:286 Isocrispatine 1:272,273 Isocurcumenol 29:90 activity in HPT assay system 29:90 Isocyanate intermediate 27:330 Isocyanide
438 Isocyanides 12:113;21:329-331,346, 349-367 by alkylation of silver cyanide 12:113 by carbylamine reaction 12:113 by dehydration of N-minosubstituted formamides 12:113 from diphosgene 12:113 from phosgene 12:113 from triphosgene 12:113 isodendrocrepine 12:286 from dendrocrepine 12:286 in nudibranchs 21:358 Isocyanide group 21:349 biosynthesis of 21:349 lsocyano derivatives 21:221 10-Isocyano-4-cadinene 21:366 2-Isocyanoallopupukeanane 21:354,365 9-Isocyanoneopupukeanane 21:351,356 9-Isocyanopupukeanane 17:16;21:365 2-Isocyanopupukeanane 21:349,351 (-)-4-lsocyanopupukeanane 21:354 (+)-9-Isocyanopupukenanane 6:82-83 by Claisen rearrangement 6:82-83 by intramolecular cyclization 6:82-83 by internal alkylation 6:80 by selective hydrogenation 6:83 from bicarbocyclic lactone 6:80 from 3,5-dimethyl-2-cyclohexan1-one 6:82-83 from hydrindanone 6:80 from Phyllidia varicosa 6:79 synthesis of 6:80,81 (+)-2-Isocyanopupukenane 6:81 by internal aldolization 6:81 from becarbocyclic lactone 6:80 from 2-ketopupukenanone 6:82 from Phyllidia 6:80 synthesis of 6:80,81 3-Isocyanotheonellin 21:366 2-Isocyanotrachyopsane 21:354 Isocycloamphilectanes 25:853 (+)-Isocycloeudesmol 6:41,42 by olefin-ketocarbene cyclization reaction 6:41 relation to cycloeudesmol 6:41
from Laurencia nipponica 6:41 synthesis of 6:41,42 Isodactylol 3:91-93 synthesis of 3:91-93 epi-Isodasycarpidone 1:58 synthesis of 1:58 Isodasycarpidone 1:58 synthesis of 1:58 Isodaucane 25:848,850 Isodeacetyl uvaricin 18:221 from Annona bullata 18:221 from Uvaria narum 18:221 hemi synthesis of 18:221,222 Isodeoxybouvardin 10:640-642 synthesis of 10:644,645 Isodeoxybouvardin methyl ether 10:640-642 synthesis of 10:644,645 Isodeoxypodophyllotoxin 26:93,213 cytotoxicity of 26:213 Isoderrone 28:228 biological activity of 28:228 Isodesoxypicropodophyllin 18:588 Isodesoxypodophyllotoxin 5:485 Isodictya setifera 25:828 Isodidemnin-1 5:422-426;10:251,253, 262,263 Isodihydrofutoquinol A 8:169,170 synthesis of 8:169,170 Isodihydrofutoquinol B 8:170 Isodihydroiridodiol 3:193 Isodihydronepelactone 16:289 Isodiospyrin 7:423 Isodityrosine 10:629-669 synthesis of 10:630 Isodocarpin 15:174 from Rabdosia ragosa 15:174 Isodomedin 15:174,175 from Rabdosia pseudo-irrorata 15:174 from Rabdosia umbrosa 15:175 from Rabdosia umbrosa var. hakusanensis 15:175 from Rabdosia umbrosa var. latifolia 15:175 Isodomoic acid E3 17:21 Isodomoic acid G&H 26:479 Isodonjaponicus 24:273;29:101
439
Isodonal 15:142,150,159,162,172,173 13C-NMR of 15:159 from Rabdosiajaponica 15:172 from Rabdosia macrophylla 15:173 IH-NMR of 15:152 Isodonoiol 15:143,152,160,172 13C-NMR of 15:160 from Rabdosiajaponica 15:172 IH-NMR of 15:152 Isodopharicin A 15:115,122,129,174 13C-NMR of 15:129 from Rabdosia pharicus 15:174 ~H-NMR of 15:122 Isodopharicin I3 15:115,122,129,174 13C-NMR of 15:129 from Rabdosia pharicus 15:174 ~H-NMR of 15:122 Isodopharicin C 15:115,122,129,174 (+)-Isodrimenin 4:403-415,419 from Drimys species 4:404 from 1-abietic acid 4:405 from dpodocarpic acid 4:405 isomerisation from drimenin 4:407,408 synthesis of 4:405-415 Isodunnianol 20:271 Isodurene disulfonyl dichloride (DDS) 14:288 Isodysidenin 25:889 Isoeburnamine 14:635,636 synthesis of 14:635,636 (-)-Isoeburnamine 9:179 Isoekebergolactone B 2:273 Isoekerbergolactone 9:95 Isoelaeocarpicine 1:283 synthesis of 1:283 (+)-Isoelaeocarpine 12:277 Isoelectric focusing 2:19,347 Isoeleuterin 4:591 (+)-Isoepicampherenol 4:674 Isoepoxyteryxin 25:471 Isoeremolactone 15:210 synthesis of 8:425-428 (+)-Isoeremolactone 15:272,273 synthesis of 15:272,273 Isoeremophilone 15:243 Isoergosterol 18:509 Isoerivanin 7:232
Isoescin Ia (triterpene saponin) 29:575 effects on HIV- 1 protease 29:575 Isoetin 5'-glucoside 7:206,207,227 Isoeucommiol 7:472,473,475,485 6-epi-Isoeucommiol 7:473 Isoeugenol 5:473,497;21:595,607; 26:227 antibacterial activity of 26:226 Isoeuonyminol 18:747;23:663,674 Isoevoninic acid 23:674 Isofagaridine 27:159 6-methoxy adduct of 27:159 Isoflavan 4:388,389,391,392 Isoflavanones 27:893 Isoflavanquinone 24:221
Isoflavone synthase 25.655 Isoflavones 4:377,378,381-385,391-394; 17:19;22:314 ;23:742;27:484,745; 28:268,269,286,287 acetyldaidzein 28:269 acetylgenistin 28:269 aglycones 28:269 bioavailibity of 28:286 daidzein 28:269 genistein 28:269 glycosides 28:269 m green split peas 28:269 m miso 28:269 in plant foods 28:269 m soy foods 28:287 m soy cheese 28:269 m soy flour 28:269 in soy sauce 28:269 m soya bean 28:269 m soya milk 28:269 in textured soya protein 28:269 in tofu 28:269 in tofu yoghurt 28:269 Isoprenylated flavonoids 28:199,203, 244 chemistry of 28:244 kuwanon C as 28:245 kuwanon E as 28:245 kuwanon G as 28:245 kuwanon H as 28:245 kuwanon L as 28:245 morusin as 28:245 mulberrofuran A as 28:245
440
mulberrofuran G as 28:245 oestrogenic activity of 28:268 oxydihydromorusin as 28:245 synthesis of 4:377,378,381-385, 391-394;17:19 Isoflavonoids 7:193;22:459;27:841 Isoflustramine D 18:691 Isofraxidin 5:515,520;7:117,120,204, 224 anticancer activity of 5:521 sedative activity of 5:521 Isofraxidin drimenylether 27:593 28-Isofucosterol 20:234 Isofulvine 1:272,273 synthesis 1:272,273 Isofutoquinol 8:170 X-ray crystallography of 8:170 Isofutoquinol B 8:170 Isogemichalcone C 28:16 as aromatase inhibitor 28:16 Isogingerenone B 17:378 Isoglutamine 6:410 isomerisation of 6:410 rearrangement to glutamine 6:409-413 Isoglycyrol 28:224,228,241 anti-Helicobacter pylori activity of 28:241 anti-microbial activity of 28:224 biological activity of 28:228 (+)-Isogmelinol 26:200,241 as PAF-induced inhibitor 26:241 Isogmelinol 5:533 Isogmenolin 26:241 as PAF-induced inhibitor 26:241 Isoguanine 15:460 Isoguattouredigine 26:825,827 Isogyrrmochrome D 15:105-107 Isogymnomitrol 13:41 Isohanalpinone 23:814 Isoharziandione 21:234 Isohelenin 29:87 activity in EBV assay system 29:87 activity in iNOS, NFkB assay systems 29:87 activity in TPA, AA, PLA assay systems 29:91 Isohemandin 18:586
Isohemandion 18:552 from Heerandia ovigera 18:552 (-)-Isohopeaphenol 26:561 Isohoslundin 2:129,134 Isohumulen 27:574 Isohumulones 24:902-904 anti-hyperglycemic effects 24:902-904 Isoiguesterim 18:776 nor-Isoiguesterin 30:694 Isoiguesterine 30:665,667 structure of 30:665 Isoiguesterol 30:693-695 against drug-sensitive strain NF54 30:694 against multidrug-resistant strain K1 30:694 structure of 30:695 Isoimperatorin 9:402 Isoindoline 8:397-403 as a2 agonists 8:397-403 synthesis of 8:400-402 Isoindoline alpha-2 antagonists 8:400 Isoindolone 8:212,217 synthesis of 8:212;13:108-115; 142 Isoingenol 1:571I synthesis 12:234-245 Isointermediol " 9:473 (x-H-Isoipecosiue 26:973 Isoiridomymercin 16:289,20:68,69,74 Isojacareubin 30:620 from hypericum 30:620 Isojuliprosine 5:211 Isokaemferide 7:411-413 trans-Isokielcorin B 26:259 Isokomarovine 14:762 from Nitraria komarovii 14:762 from quinoline-5-carboxylic acid 14:763 synthesis of 14:763 via Bischler-Napieralski condensation 14:763 Isolactarane 17:154 Isolancerotriol 5:736 13C-NMR spectrum of 5:736 5-isovalerate of 5:736 Isolariciresinol 20:108,620;26:195,205 (+)-Isolariciresinol 26:268
441
Isolasalocid A 11:152 Isolaserpitine 5:725 Isolation 27:164-166 of chelilutine 27:156-166 Isolaulimalide 19:568 Isolaurenterol 25:787 Isolaurepinnacin 19:411 synthesis of 10:210,213 (2S,3S)-Isoleucine 10:277,278; 22:33,381 (2R,3S)-alloisoleucine from 10:277,278 Isolevoglucosenone 14:279 synthesis of 14:279 Isolexins 5:578 Isolichenan 5:309,310,322 Isolicoflavonol 28:17,224,243 anti-Helicobacter pylori activity of 28:243 anti-microbial activity of 28:224 as aromatase inhibitor 28:17 Isolimonen 20:13 (+)-trans-Isolimonene 29:83 activity in AM assay system 29:83 6-epi-Isolincosamine 11:446 Isoliquiretin 22:425 Isoliquiritigenin 22:425;28:228 biological activity of 28:228 Isoliquiritoside 22:424 Isoliquirtin 24:893-895 inhibitory effect in inflammation 24:893-895 Isoliquirtogenin 25:537,539 Isolobophytolide 8:15,19-32;10:10-13 antitumor activity 8:15,19-32 synthesis of 8:19-32 from Labophytum crassum 8:20 ~H-NMR spectrum of 8:20 X-ray analysis of 8:20 synthesis of 10:10-13 Isolongifolene 4:639 Isolongirabdiol 15:142 13C-NMR of 15:159 from Rabdosia longituba 15:172 tH-NMR of 15:151 Isolugrandoside 26:328,329 acetate of 26:329 Isomagellanol 18:746
Isomagnolin 26:201,241 Isomagnolol 26:227 Isomalabaricane triterpenes 21:254,273, 285 Isomaltase 499,504,505,38:7:57 Isomaltose 15:436 Isomaltoside 11:469-471 synthesis of 11:469-471 Isomarchantin C 2:283,284 (+)-Isomedicarpin 4:382,383 tuberostan from 4:382,383 synthesis of 4:382,383 Isomelodienone 9:400 Isomenthol 17:605;25:155 (+)-Isomenthol 21:585;29:83 activity in AM assay system 29:83 (+)-Isomenthone 21:585 Isomenthone 27:375 (-)-Isomenthone 29:83 activity in AM assay system 29:83 c~-Isomer 10:349 from enone 10:352 [3-Isomer 10:354 by 1,4-addition of thiolane anion 10:354 cis-Isomer 30:549 radical anions of 30:549 D-lyxo-Isomer 5:705,706 Isomerase 17:480 IDP-Isomerase 7:324 Isomerism 27:361 of monoterpenoids 27:361 Isomerization 1:189,413,414,447,448, 532;6:117,126,153-155,157,221, 541,542,556;10:410;16:236,371,615; 23:195 acid catalyzed 16:236 iodine catalysed 6:141 of carbon-carbon double bond 16:371 of cyclosterol 16:332 ofdiene 1:447,448 of glutamine 6:410 of isoglutamine 6:410 of N-cyclohexylisopropylamine (MMA) 1:532 of olefins 1:413,414
442
of azatidine acetates 23:195 photochemical 413,414 silylatropic 10:111 to catechol 16:615 with camphorsulfonic acid 6:222 with iodine/benzene 1:447,448 with methyl magnesium derivative 1:532 R,S Isomerization 6:141 cis-Isomerization 6:153,162 trans, cis-Isomerization 6:141,142 Isomerization process 27:350 kinetic characteristics of 27:350 Isomerization rates 27:350 of 8'-hydroxyabscisic acid 27:350 ofphaseic acid (PA) 27:350 Isomers 14:526-531 of 2-methyl-l,6-dioxaspiro [4.5] decane 14:526-531 synthesis of 14:526-531 Isomethuenine 5:126 Isomethuenine-N-oxide 5:126 (+)-Isomintlactone 19:153 preparation of 19:152 Isomitocins 13:445-467 mitomycins from 13:445-467 Isomitomycin A 13:434,445,446,453 from Streptomyces caespitosus 13:2 synthesis of 13:460-469 Isomitraphylline 25:25,26 Isomolvizarin 18:193 Isomucronulatol 7,2'-di-O-13-Dglucoside 27:499 Isomultiflorenol 7:164,165 Isomuramic acid 6:386 Isomycorhodin 2:140 DEPT spectra 2:142 hetero COSY spectra 2:142,143 sugar residue of 2:143 Isomyricanon 17:372 Isonaamidine 17:17 Isonaamine A 17:17,18 Ag'9-Isonakafuran-9 6:70 synthesis of 6:70 Isonakafuran-type sesquiterpenes 25:692 Isonaringin 26:744
Isoneriucoumaric acid 9:293-299 Isongaione acetate 15:237 Isoniazid 2:424 Isonicotinic acid hydrazide (INAH) 23:94 7-cis-Isonieratene 6:155,156 Isonimocinolide 9:297-299 Isonitramine 14:742-750 13C-NMR of 14:742 diastereoselectivity in 14:743-747 enantioselective synthesis of 14:743-747 from L-prolinol 14:743-747 from Nitaria sibricia 14:541 1H-NMR of 14:742 synthesis of 14:543 Isonitrarine (3-epinitrarine) 14:760 biosynthesis of 14:760 Isonitrile 12:411,414 aldol reaction of 12:411,414 2-amino alcohol by 12:411,414 with aldehyde 12:411,414 Isonitrile 17:14 Isonitrile reduction chemistry 12:211 (-)-Isonootkatone 16:239 Isonovaldal 25:152 Isonoyanine 20:265 Isoorientin (luteolin 6-C-glucoside) 29:579 effects on ACE 29:579 2-Iso-oxacephems 12:126 antibiotic activity of 12:126 Isooxazolidine-4-carboxylic acid 12:156 (-)-c~-Isoparteine 27:259 conformational studies of 27:258-259 Isoparvifolinone 5:800,801 formation from parvifoline 5:800,801 ozonolysis 5:800,801 (+)-Isopeduncularine 11:284,285 13C-NMR of 11:285 synthesis of 11:284,285 Isopelletierine 12:284 Isopenicillin 11:211 Isopenicillin-N-synthase 11:212,213 Isopentalenene 3:6,61
443 Isopentaquine 22:150 Isopentenol 7:104;8:70 Isopententenyl diphosphate 11:219-222 farnesyl diphosphate from 11:219-222 formation of 11:219-222 from mevalonate 5-diphosphate 11:219-222 geranyl diphosphate from 11:219-222 Isopentenyl diphosphate 7:322-324,330, 348,352 Isopentenyl pyrophosphate 21:721; 22:255 Isopentenyl tRNA 22:255 Isopentenyl-diphosphate: dimethylallyl diphosphate isomerase 11:201 from Saccharomyces cerevisae 11:201 Isopentyl diphosphate (IPP) 25:130 2-Isopentyl-3-(E-4-methylpent- 1-enyl)5-methyl-pyrazine 5:265,266 Isoperoxisomicines 22:568,582,593, 594,596 Isopetasin 29:87 activity in 5LOX, PLA assay systems 29:87 Isophorone 26:297,298,307 microbial transformation of 26:307 Isophysodic acid 20:283 Isophytolaccagenin 7:144,145 Isophytolaccinic acid A 7:144,145 Isopicropodophyllone 5:481,483;26:193 Isopicrostegane 26:196 ent-Isopimar- 15-en-6a, 7 c~,8c~-triol 15:170 13C-NMR of 15:170 from Rabdosia parvifolia 15:173 IH-NMR of 15:169 ent-Isopimarane 15:112 Isopimaric acid 20:690 from Salvia candidissima 20:690 from Salvia heldrichiana 20:690 from Salvia wiedemanni 20:690 Isopimpinellin 22:522,539;23:352 Isopinocampheyl borane 13:71 Isopiperitenol 25:150
(+)-Iso-plumericin 16:301 synthesis of 16:301 L-Isopodophyllotoxone 18:600 Isopregnomisin 23:773;26:249 Isoprene 4:394 chromanes from 4:391,396,398 (Z)-Isoprene 8:65 Isoprene intermediate 22:379 Isoprene-rule diterpenes 11:4 Isoprenoid biosynthesis 17:471 Isoprenoid metabolites 11:219-222 Isoprenoid pathway 21:276 metabolites derived from 21:276 Isoprenoid quinones 30:304 in arthropods 30:304 in sea lichens 30:304 Isoprenoid unit 25:513 Isoprenoids 6:133,185;16:662-670 synthesis of 16:662-670 Isoprenyl- 1,4-naphthoquinones 29:735 biosynthesis of 29:735 Isoprenylated flavonoids 28:199,203, 207,244 biological activity of 28:199 effect on testosterone 5~reductase 28:244 from medicinal plants 28:199 hypotensive action of 28:207 Isoprenylation 11:200 by 4-(y,y-dimethylallyl) tryptophan synthase 11:200 of tryptophan 11:200 Isoprenylphenols 17:451,20:271 biosynthesis of 17:747 Isopristimerin III 7:149,760 2-Isopropenylnaphtho [2,3-b] furan-4,9dione 20:494 Isopropyl 1-thio-[3-D-galactopyranoside 8:315 13-Isopropyl pimelic acid 25:154 8-Isopropyl-2,5-dimethyl- 1,4-naphthoquinone 14:319 5-Isopropyl-3,7-dimethyl- 1H-inden- 1one 14:328,329 5-Isopropyl-3,7-dimethyl- 1-oxo- 1Hindene-6-carbaldehyde 14:319 7-Isopropyl-4-methyl- 1-azulenecarbaldehyde 14:319
444 3-I sopropyl- 8-(3,7- diisopropyl- 1azulenyl) benzofulvene 14:340 Isopropylcatechol 14:684-686 taxodione from 14:684-686 (R)-2,3-Isopropyliden 12:21,22 glyceraldehyde 12:21,22 O-Isopropylidene 6:269,270 protection with 6:269,270 5,6-O-Isopropylidene 1,2-(methoxycarbonyl)ethylidene-ot-Dgalactofuranose 14:233 1,2-O-Isopropylidene derivative 6:279,280,285,286 from D-xylose 6:269,270 from L-xylose 6:269,270 (R)-2,3-Isopropylidene glyceraldehyde 18:181 D-Isopropylidene glycerldehyde 19:166
1,2-O-Isopropylidene-(-)-swainsonine
12:317 2,3-O-Isopropylidene-l,6-di-O-ptoluenesulfonyl-c~-L-sorbofuranose 10:528 4,5, O-I sopropylidene-2-methylpent-2ene- 1,4,5-triol 10:436,437 Claisen rearrangement of 10:436,437 with triethyl orthoacetate 10:436,437 2,3-O-Isopropylidene-D-erythrose 12:318 1,2:5,6-Di- O-Isopropylidene-D-glucose 12:41 vinyl iodide from 12:41 1,2-O-Isopropylidene-D-glyceraldehyde (1,3-dioxolane) 10:437,438 Isopropylidene-D-glyceraldehyde 30:469 addition of 30:469 2,3-O-Isopropylidene-D-glyceraldehyde 6:353 2,3:5,6-di-O-Isopropylidene-D-mannose 30:452 nucleophilic acylation of 30:452 2,3-O-Isopropylidene-L-erythrose 12:330,331 (-)-8-epi-swainsonine from 12:330,331 (-)-8a-epi-swainsonine from
12:330,331
(-)-8,8a-di-epi-swainsonine from
12:330,331 Isopropylidene-L-threitol 19:1672,31,8-O-Isopropylidenylcastanospermine 12:345 (-)-Isoprosopinine 12:435 (-)-Isoprosopinine A 12:475 Isoprostane F2a 25:596 Isoproterenol 25:594,896 Isoprotostemonine 21:770 Isoptaquiloside 26:719,722 Isoptera 19:118;22:371 (+)-Isopteropodine 13:490,491 Isopteryxin 25:471,476 (-)-Isopulegol 16:268 Isopulegol 25:136 (-)-Isopulegole 21:585 Isopulmericin 16:299 antifungal activity of 16:299 antileukemic activity of 16:299 cytotoxic activity of 16:299 3,4-O-Isopyrilidene-3,3,4,5'-tetrahydroxy-stilbene 22:626 Isopyrilidene-derivative 22:626 Isopyrum thalictroides 29:578 Isoquercitin 7:227;22:645;29:573,579 effects on ACE 29:579 effects on HIV-1 protease 29:573 Isoquinoline 10:185,673,674;25:4,542, 824,825 ;30:563-567,588 against cancer cell lines 30:588 based PKA inhibitor 25:542 from genus Hernandia 30:563-567 Isoquinoline alkaloids 1:168;5:3,42, 494,265,266;13:642;21:107,733; 27:819,863;30:560,562,588,590,594, 597 (-)-salsolinol 25:531 (+)-corytuberine 30:589 (+)-hemovine 30:589 (+)-laurotetanine 30:589 (+)-magnoflorme 30:589 (+)-N-formyldehydroovigerine 30:589 (+)-N-formylnomantenine 30:589
445
(+)-N- formylovigerine 30:589 (+)-N-hydroxyhemangerine 30:589 (+)-N-methylhernangerine 30:590 (+)-ovigerine 30:590 7-formyldehydrohernangerine 30:589 7- formyldehydroovigerine 30:589 7-hydroxy-6-methoxy- 1methylisoquinoline 30:589 7-oxohernagine 30:590 against cancer cell lines 30:588 annelated benzazecines from 6:483 antiplatelet aggregation activity of 30:560 atherosperminine 25:540 cytotoxicity of 30:560 benzoxanecines from 6:483 demethylsonodione 30:589 dihydropyranocoumarins 25:540 dopamine 25:531 Epstein-Barr virus inhibition due 30:560 hernandonine 30:589 hernanymphine 30:589 Isoquinoline derivatives 6:495,496 Isovanillin 30:567,594 methano-bridged benzoxaxecines from 6:483 narceine 25:533 N-hydroxyovigerine 30:589 N-methylcorydaldine 30:589 N-methylovigerine 30:590 phenylpropanoid glycosides 25:540 synthesis of 1:187-226 thalifoline 30:590 Isoquinoline N-oxides 6:468 pyrolysis of 6:468 Isoquinoline-derived alkaloids synthesis of 6:467-502 Isoquinolinequinones 10:77-145 ;21:265 as antibiotics 10:77-145 from actinomycetes 10:77-145 from marine sponges 10:77-145 naphthyridinomycin type
10:77,103-115 saframycin type 10:77-103 synthesis of 10:77-145 Isoquinolines 17:91 Isoquinolines synthesis of 1:168 Isoquinolinium betaine 1:189 Isoquinolinium salt 14:503 cycloaddition of 14:503 with chiral dienophiles 14:503 Isoquinolino-pyrrolinedione 3:465,466 photochemical reaction of 3:465, 466 Isoquinuclidine 1:112 (+)-3-Isorauniticin 16:437 synthesis of 16:437 Isorauniticine 9:171 3Isorenieracistene 6:155,156 Isoreserpic acid lactone 25:24 conformation 25:24 Isoreserpiline 1:158;5:128 conversiont to bleckerine 1:158 Isoreserpine 13:410;25:3,13,29 conformation 25:23 Isoretronecanol 1:231,233,235-237,241, 244,247-251,253,256,257,259,260, 325,326,339 (+)-Isoretronecanol 13:483,484 synthesis of 13:483,484 Isoretronecanol 3:54;14:737 from dihydrofuran 14:737 synthesis of 14:737 Isoretronecanolate 1:248 synthesis of 1:248 Isoretronecic acid 1:265,266 synthesis of 1:265,266 Isoretulinal 1:36 Isoretuline 1:38,39 Isorhamnetin 5:652;7:206,227;29:577 effects on N-aminopeptidase 29:577 [3-Isorhodomycinone 4:318 by C-prenylation 4:382,384 from desoxybenzoin 4:383,384 Isorhodoptilometrin-2'-sulfate 28:718 Isorhynchophylline 25:26 Isoriccardin C 2:283,284 Isoridentin 7:230 (-)-Isoroemerialinone 2:257 Isorugosin D 23:405,408
446
Isorugosin E 23:405,408 Isoryanodol-type diterpenes 26:852 insecticidal effects of 26:852, 1136 Isosabandin 7:225 Isosaccharinolactone Isosacculatal 2:278,279 Z-Isosafrol 8:161 Isosakuranetin 7:228;23:747;26:744 Isosalutaridine 18:58 Isosandwichine 9:183,185 Isosarmentosin 21:738,740 Isoschaftoside 7:227 Isoschumanniophytine 21:145 Isoscopoletin 5:515,516;26:315,332, 333,334,342 Isoscopoletin-13-D-glucoside 5:515,516 Isoscutellarein 5:624,627,658 Isoscutellarein-4'-methyl ether 7glycosides 5:658 Isosegoline A 23:276 Isoshinanolone 2:213,215,216,222,225, 227,228;5:754,755 biosynthesis of 2:227,228 CD curve of 2:226,227 chemical interconversion of 2:222,223 configuration of 2:224 ~H-NMR spectrum of 2:227 oxidation with DDQ 2:227 physical data of isomers 2:225 stereoisomers of 2:222 structure and stereochemistry 2:222-225 UV spectra of 2:226 epi-Isoshinanolone 2:213,215,216, 222-224 neo-Isoshinanolone 2:222,224 Isosilymarin 5:496 Isosinensetin 23:747 Isositsirikine 2:375,125;9:168 16-epi-Isositsirikine 5:125 E-Isositsirikine 9:171 Z-Isositsirikine 9:171 Isosolenopsin A 1:389,390 synthesis of 1:389,390 (+)-Isosophoramine 18:323
(+)-~-Isosparteine 27:259 conformational studies of 27:258-259 Isospiciformin 27:568 5-epi-Isospongiaquinone 15:315,318 Isospongiaquinone 15:315,418 Isostatine 10:263,266-269,272-275, 278-284 (3S,4R,5S)-Isostatine 12:476,477 (-)-Isostegane 29:389 steganes synthesis of 29:389 Isostemotinine 21:759,762 Isosterism 13:165 Iso-steviol activity 29:100,101 Isostigamasterol 18:515 Isostrychinine 26:1051,1052 Isostrychnine-N-oxide 26:1051 Isoswertianoline 22:533,541 Isoswinholide A 26:1197,1198,1229 paterson's synthesis of 26:1229 Isotaxiresinol 20:108 Isotaxiresinol-6-methyl ether 20:107 Isotelekin 7:233 Isotenulin 20:10 Isotetracenone antibiotics 5:596,597 (+)-Isothebaine 16:512 Isothiocyanate 17:14;21:329-331,346, 349-367;25:514;28:658 as terpenes 28:658 as precursor of formamido group 28:658 in nudibranchs 21:358 (+)- 10-Isothiocyanato-4,6-amorphadiene 25:852 7-Isothiocyanato-7,8-dihydro- abisabolene 25:848 (+)-4-Isothiocyanato-9-amporphene 25:852 (+)-l-Isothiocyanatoaromadendrene 25:853 10-Isothiocyanatobiflora-4.15 diene 25:854,856 (+)-Isothiocyanatocubebane 25:853 (-)- 10-Isothiocyanatoguaia-6-ene 25:852 (-)- 10-Isothiocyanatokalihiniol G 25:856
(-)- 15-Isothiocyanato-l-epi-kalihinene 25:856
447
Isothiocyanato-N-(4-nitrophenyl) benzeneamine (amoscanate) 26:481 (+)-5-Isothiocyanatopapukeanane 25:853 2-Isothiocyanatopupukeanane 21:346, 349 (-)-9-Isothiocyanatopupukeanane 21:354 5-Isothiocyanatopupukeanane 21:365 (+)-6a-Isothiocyano-5aH,7aH, 10aendesm-4-(14) ene 25:852 (-)- 11-Isothiocyano-7-flH-endesm-5ene 25:852 (+)- 10R-Isothiocyanoalloaromadendrane 25:853 (-)- 10a-Isothiocyanoalloaromadendrane 25:853 2-Isothiocyanotopupukeanane 21:356 9-Isothiocyanotopupukeanane 21:356 (+)-(1R, 6S, 7S, 1OR)-10-Isothiocynato-4amorphene 25:852 (-)-(IS, 6R, 7R, 10R)- 10-Isothiocynato-4amorphene 25:852 2-Isothiocynoto-6-axene 25:850 Isothiouronium salts 8:316 (-)-4a-Isothioyanatogorgon-11 -ene 25:852 (-)-3-Isothuj one 27:384 Isothujone 7:95,98,99,101 Isotingenone 18:760 Isotingenone III 18:760 (-)-Isotirucallol 16:211 biomimetic synthesis of 16:211 Isotissoclinotoxin A 25:833,834 Isotope effect 9:96,102-106,475,476; 27:348 Isotope pattern 2:43,44 Isotope shifts 9:106 Isotopic analysis 13:334-337 Isotopic distribution 2:2,25 lsotricha 2:294 Isotrichodiol 13:524 Isotriptophenolide 23:685 Isotussilagin 1:230,231 synthesis of 1:230,231 Isovaleraldehyde 4:396,398 5-Isovalerate 5:725,727 of ferutriol 5:725,727
of isolancerotriol 5:725,727 of lapiferol 5:725 Isovalerate 5:735 13C-NMR spectrum of 5:735 of erpoxyisolancerotetrol 5:725,727 of epoxyjaesehkeanandiol 5:735 of isolancerotetrol 5:725,727 6[3-Isovaleroxylabda-8,13-dien-7c~, 15diol 17:27 Isovallesiachotamine 5:125 Isovangustin 7:233 Isovanihuperzine A 21:747 Isovanillin 30:567,594 as platelet aggregation inhibitor 30:594 Isovanilline 21:747 Isovelbanamine 14:866-867 from 1-glutamic acid 14:866-867 synthesis of 14:865-867 via thio Claisen rearrangement 14:865-867 Isovelleral 26:461 Isovincadifformine 14:850-853 synthesis of 14:850-853 Isovincoside (strictosidine) 6:520 Isovitexin (apigenin 6-C-glucoside) 7:227;29:579 effects on ACE 29:579 Isovoacangine 5:127;9:174 7S-Isovoacristine 5:128 Isowildordic acid 23:674 17-Isowithanolide 20:246 Iso-Withasomine 1:343 synthesis of 1:343 Isoxaben 26:370 Isoxanthochymol 22:659 Isoxazolidine 1:230,231 ;19:42 synthesis of 1:230,231 [3-aminoalcohol from 12:290 hydrogenation of 12:290 Isoxazolines 12:20-22 Isoxazopodophyllic acid 26:214,215 Isoyangambin 26:242 as PAF-induced inhibitor 26:242 Isozeylanone 2:212 Isozonarol 6:17 from Dictyopteris undulata 6:17 Rau synthesis of 6:17
448 synthesis of 6:17,18 Welch synthesis of 6:17 Isozonarone 15:297 Isozymes 17:481 ;30:827,828,843,826, 829 F-I as 30:826 F-I-0 as 30:826 F-I-2 as 30:826 F-II as 30:826 F-I-I as 30:826 F-II as 30:843 F-Ill as 30:826 F-III-1 as 30:826,843 F-III-2 as 30:826,843 from Phaseolus vulgaris 9:563 immunological analyses of 30:829 Iso-[3-peltatin B methyl ether 18:59 ISP 21:555 Istanbuline D 20:660 from Salvia yosgadensis 20:660 ltersonilia tilletiopsis 5:291 Itocyclization 10:6 Itodulosides I-V 27:41,45,46,47 structures of 27:46,47 Itraconazole 22:60 Iva xanthifolia 5:728 (+)-Ivalin 10:405,406 Ivermectin 12:8,9;26:441,447,453,457, 468;28:396 as macrolide antibiotic 28:396 biological activity of 12:8,9 Ivy PNP 25:383 Ixocarpalactone 20:241,242 Ixocarpalactone A 20:185,194,223 Ixocarpalactone B 20:181,194 Ixodes ricinus 26:695
(+)-Jaborol 20:181 Jaborosa bergii 20:180 Jaborosalactone A 20:234 Jaborosalactone F 20:223,20:242 Jaborosalactone M 20:181 Jacaranda acutifolia 5:682 Jacaranone 16:616 Jaceidin 7:227 Jaceosidin 7:227 Jaceosidin-7-sulphate 5:655
Jaceosidine-7,4'-disulphate 5:655 Jadiffine 9:172 Jaeschferin 5:722,725 Jaeschkeanadiol 5:722,723,730-332 JAK/STAT- linked receptors 25:520 JAK/STAT pathway 25:519 Janolus cristatus 28:146 Janolusimide 28:146 from Janolus cristatus 28:146 neurotoxic lipophilic activity of 28:146 Janua bioticus 17:100 Japonenyne A and B 25:802 Jarsin (L1 160) 22:693,694-700 Jasmin flowers 19:158 Jasmin-flower oil 6:557 Jasminin 7:443 Jasminum grandiflorum 19:152, 158-159;29:581 Jasminum officinale 7:218,222,223 Jasminum sp. 7:218,219 Jasmolin I 27:588 Jasmolin II 27:588 Jasmonates 25:367,373 Jasmone 9:534,536 cisJasmonic acid 6:557;25:374;27:64, 71-73 biological activities of 27:72,73 generation of 27:71,72 Jasonia candicans 21:599 Jasonia montana 21:599 Jaspamide 5:429;25:757,768;26:485 anthelmintic activity of 5:429 antifungal activity of 5:428 derivative 25:768 insecticidal activity of 5:428 Jaspis 5:428;19:580;613;21:273; 25:700,714 ;26:485,488,1210;28:697 Jaspis coriaceae 25:725 Jaspis splendans 25:768 Jaspis sponges 21:252 jaspamide from 21:252 Jaspisamides 25:727 Jaspisin 28:697 sea urchin hatching inhibition by 28:697 Jasplakinolide 26:485 Jaspsamide A 25:727 Jasus lalandii 29:10
449 Jatamansone 22:527,540 Jatorrhizine 11:201-204 by Berberis cell cultures 11:201-204 formation of 11:201-204 from columbamine 11:201-204 Jatrihizine 21:733 Jatrogrossidione 26:809,811 Jatropha curcas L. 22:524 for convulsions and fits 22:524 Jatropha gossypifolia L. 10:152;22:524 as anticonvulsant 22:524 Jatropha grossidentata 26:809,810 Jatropha isabelli 26:810 Jatropha multifida L. 22:524 as anticonvulsant 22:524 Jatrophane 2:262 Jatrophone 10:152,155,156;26:809 Jatrorrhiza palmata 27:749 Jatrorrhizine 21:84 4,4'-bis-Jatrorrhizine (v) 27:749 and electron transfer 27:749 Jauch 29:127 sesquiterpenoids drimane-type synthesis by 29:127 Jaundice 22:643 JB6 cell line 30:593 tumor-promotion in 30:593 JB6 cell line transformation 30:592 inhibition of 30:592 Jegosapogenol 21-(2,3-dihydroxy-2methyl)-butanoate)-22-angelate 7:139,141 Jeiranbatanolide 7:235 Jeitacin A&B 26:442 Jenisseensoside C 26:47,55 granulocyte phagocytosis of 26:47,55 Jenisseensoside D 26:47,55 granulocyte phagocytosis of 26:47,55 Jenisseensosides A-D 26:46 cyclooxygenase inhibitory activity of 26:46 Jenkins's synthesis 12:185,186 Jereicopsis 26:1175 Jereicopsis graphidiophora 26:1206, 1207,1214 Jereisterol B 26:1206,1207
Jerumanis method 21:511 metal complexing assays 21:511 (+)-Jerusalemine 29:377 allocolchicinoids total synthesis of 29:377 Jerveratrum group 23:563 Jervine 7:16,17,21,22;21:97;23:563, 565,575 Jessie acid 25:182 Jessie acid arabinoside 25:182 Jessie acid xyloside 25:182 Jeunicin 17:22 JICST-E 19:758 Jinbricatime 25:824 Jinyinhouside A 21:656 Jiuhuanin A 15:130 13C-NMR of 15:155 from Rabdosia macrocalyx var. jiuhua 15:173 lH-NMR of 15:146 Johnson synthesis 14:681-684 oftaxodione 14:681-684 Johnson-Claisen rearrangement 10:428-438 ofallylic alcohols 10:428-438 of aldoheptofuranoses 10:432-436 of D-glyceraldehyde derived allylic alcohols 10:436,437 of 4-(3-hydroxy- 1-propenyl) derivatives 10:436-438 of L-lyxofuranose derivatives 10:431,432 Johnson-Lemieux reaction 3:328 Jones map 17:539 of amino acid residues 17:539 Jones model 17:507 Jones oxidation 4:50,456,465,470, 490-492;16:29,30,72,323,248,235, 514,595,627,641,551,558;19:252, 304,320-321 ;21:715 ;22:277 ;26:1209, 1225 Jones reagent 6:17,25,55,78,509,515, 461 ;12:466,508,613; 14:818;19:173, 428 reaction with stypodiol methyl ether 6:55 Jorunna funebris 21:265 Jospis sp. 25:704,719,727,731
450
Jotismati 23:654 Joullie method 10:283 Jourdan-Ullman condensation 13:353-355 Ju-Fang synthesis 6:14 of (+)-polygodial 6:14 of (-)-polygodial 6:14 of (• 6:14 Juglans 26:905 Juglans mandshurica 26:899 Juglans regia 21:503;23:342;28:424 Juglone 9:258;26:363,370,470,638, 868;30:313 structure of 30:313 Juglone derivative 4:396,398 synthesis of 4:396,398 Jujubasaponins II-VI 27:42,48-50 structures of 27:49,50 Jujuboside B 27:41,42,45,46 structure of 27:46 Julandine 1:363 synthesis of 1:365,367 Julia coupling 1:457,458,461-464 Julia olefination 16:230;21:397 ;26:1219 Julia reaction 1:454,456 Julia sulfone 1:463 Julia synthesis 9:356 of 22,23-dihydroavermectin B ~b 12:17-19 Julibroside I 25:208 Julibroside II 25:208 Julibroside III 25:208 Julichrome Q1 20:277 Julifirosine 5:211 Julifloridine 5:211 ;9:70 Juliflorine 5:211 Juliflorinine 5:211 Juliprosine 9:72 Juliprosinene 9:71,72,77 Juliprosopine 9:70 Jungermannia infusca 2:280 Jungermanniaceae 25:252 Juniper communis 21:616 Juniperus 27:372 (+)-limonene in 27:372 Juniperus communis 5:485;20:16 Juniperus foetidissma 8:163 8,14-cedranoxide from 8:163 Juniperus macropoda. 22:524
Juniperus occidenatalis 28:408 Juniperus procera 25:257,259 Juniperus sabina 20:16;26:214 Juniperus virginiana 15:346;20:16; 28:408 Junosidine 13:348,349 from Citrusjunos 13:348,349 Junosine 13:348,349 from Citrusjunos 13:348,349 Juriperus communis 27:370,372 essential oils from 27:370 Jusiaea decurrens 9:214 Justicia procumbens 17:333;26:226, 235,243,265 justicidin B from 26:243 justicidin E from 26:243 neojusticin A from 26:243 taiwanin E from 26:243 taiwanin E methyl ether from 26:243 diphyllin apioside-5-acetate from 26:226 diphyllin asioside from 26:226 diphyllin from 26:226 justicidin A&B from 26:226 Justicia procumbens var. leucantha 26:226 diphyllin apioside-5-acetate from 26:226 diphyllin asioside from 26:226 diphyllin from 26:226 justicidin A&B from 26:226 Justicia prostata 17:335 Justicidin B 26:243 as PAF-induced inhibitor 26:243 Justicidin D (neojusticin A) 26:194 Justicidin E 26:243,265 as PAF-induced inhibitor 26:243 (+)-Juvabione 16:211 synthesis of 16:211 Juvabione 22:383;25:546 Juvenile hormone (JHI) 1:704-707 synthesis of 1:704-707 Juvenile hormone III 1:704,705;22:369, 370,371 from Coleoptera 22:371 from Dictyoptera 22:371 from Hymenoptera 22:371 from lsoptesa 22:371
451 from Lepidoptera 22:371 from Orthoptera 22:371 synthesis of 1:704,705 Juvenoid activity 22:384 Juvenoid effects 22:386 ofjuvabione 22:386 Juvenoids 22:383,395 Juvocimene I 22:392 Juvocimene II 22:354,392,395 K + channels 25:530-531,534 K+-channel mediated ion transport 25:497 K-252a ("SF-2370") 12:366,368 K-252b 12:384 from Nocardiopsis sp. K-290 12:366,368 protein kinase C inhibitor of 12:384 K-252c (staurosporinone) 12:366,368, 369 from Nocardiopsis sp. K-290 12:366,368,369 protein kinase inhibitor of 12:386 synthesis of 12:379-381 K-252d 12:366,368,369,386 Nocardiopsis sp. K-290 12:366, 368 protein kinase inhibitor of 12:386 K-25a 12:366,368,369,384,390,395, 396,398,399 anihypertensive activity of 12:398 antaillergic effect of 12:398 antiinflammatory effect of 12:398 antitumor activity of 12:395 effect on nerve growth factor 12:396 porcine spleen protein kinases inhibitor of 12:390 prostaglandin production by 12:399 protein kinase A inhibitor of 12:384 protein kinase C inhibitor of
12:384,390 protein kinase G inhibitor of 12:384 K562 cells study 27:877 KA-antibiotcs 4:434 in carbapenem 4:434 Kabalka's procedure 6:547,548 Kadsura heterocollita 26:240,249,259 burchellin from 26:249 gomisin M from 26:240 heteroclitin F from 26:259 heterociitin G from 26:259 kadsurenone from 26:249 Kadsura interior 26:223 gomisin-G from 26:223 interiotherin A from 26:223 schisantherin D from 26:223 Kadsura sp. 17:346 Kadsuranin 26:197,224 Kadsurenin H 26:240 as PAF-induced inhibitor 26:240 Kadsurenone 16:561 ;26:240,241,249 as PAF-induced inhibitor 26:240 Kadsurujaponica 26:255 Kaemferol 30:224 from natural flavonol 30:224 Kaempferia 23:840 Kaempferia galanga 23:840;24:273 Kaempferol 7:206,227;22:317,615, 661 ;25:541,544,546,594,615;26:747, 748,750,763,764,769;29:573 effects on HIV- 1 protease 29:573 Kaempferol-3,7,4'-trimethyl ether 23:797 Kaempferol 3-glucoside 23:761 Kaempferol 3-methyl ether 20:712 from Salvia yosgadenis 20:712 Kaempferol 3-O-(2"-f3-D- xylopyranosyl)-cz-L- rhamnopyranoside 28:64, 65 anti-oxidant activity of 28:64,65 Kaempferol 3-O-(6"-O-rhamnopyranosyl)galactopyranoside 7-0glucopyranoside 5:633 Kaempferol 3-O-a-L-rhamnopyranoside 28:64 Kaempferol 3-rutinoside 23:747
452 Kaempferol-3-O-(2"- O-galloyl)glucoside 29:579 effects on ACE 29:579 Kagan' s ether 30:215 cyclisation of 30:215 mechanism of formation of 30:215 Kahweol 29:101 activity in skin-6 bioassay system 29:101 activity in CYP bioassay system 29:101 activity in GSH bioassay system 29:101 activity in GST bioassay system 29:101 Kaikasaponin I 25:111,112,115,116,118 Kaikasaponin III 25:95,99,104,115,116, 118 allo-Kainic acid 1:328,329,334,335 synthesis of 1:328,329,334,335 Kainic acid 12:446;21:70,302;25:529 (-)-ct-Kainic acid 26:478 Kainic acid-binding glutamate receptors 25:529 Kainoids 21:302 Kairomones 8:219;22:95 Kakkasaponin I 25:95,104 Kakkasaponin III 25:111,112 Kala-azar 2:302 Kalafungin 4:591,617,618,128 Kalecide 21:381 Kalihinane diterpenes 26:810 cycloamphilectanes 26:810 7,20-diisocanoisocycloamphilec tane 26:810 epiamphilecladienc 26:810 7-isocyano- 11 (20), 14,7isocyano-cyclo-amphilect-10ene 26:810 isocycloamphilectanes 26:810 Kalihinane diterpenoids 25:689 Kalihinanes terpenoids 27:877 Kalihinenes X,Y and Z 21:366 (+)-Kalihinol 25:856 Kalihinol A 21:331,366;25:757; 26:466,810,812 Kalihinol E 21:331,366 Kalihinol-F 21:331.351
Kalihinols 25:854 (-)-Kalilinol G 25:856 Kalinanes 25:782 (-)-Kalinihol 25:856 Kalinihol I 25:856 Kalinihol J 25:856 Kalipyran B 25:783 Kalization 24:194 Kallilolides 23:180 Kalopanax pictus 30:203 use in folk medicine 30:203 use in rheumatoid arthritis 30:203 Kalopanax pictus 30:203 use in rheumatoid arthritis 30:203 Kalopanax saponins 15:191 Kalopanaxsaponins-A 30:203 antinociceptive effect of 30:204 Kalopanaxsaponins-I 30:203 antinociceptive effect of 30:204 kappa-opioid receptor 30:205 activation by (+)-allomatrine 30:205 activation by (+)-matrine 30:205 kappa-opioid receptor activation 30:207 by menthol 30:207 Kamebacetal A 15:135,137;29:101 activity in NFkB bioassay system 29:101 activity in NO bioassay system 29:101 from Rabdosia excisa 15:171 from Rabdosia henryi 15:172 from Rabdosia latifolia var. reniformis 15:172 from Rabdosia umbrosa var. leucantha 15:175 IH-NMR of 15:145 Kamebacetal B 15:137 from Rabdosia umbrosa var. leucantha 15:175 IH-NMR of 15:148 Kamebakaurin 15:117,125,131,175; 29:101 activity in NFkB bioassay system 29:101 activity in NO bioassay system
453 29:101
~3C-NMR of 15:131 IH-NMR of 15:125 from Rabdosia excisa 15:171 from Rabdosia henryi 15:172 from Rabdosia inflexa 15:172 from Rabdosia longituba 15:173 from Rabdosia serra 15:174 from Rabdosia umbrosa 15:175 from Rabdosia umbrosa var. leucantha 15:175 Kamebanin 15:171;29:101 activity in NFkB bioassay system 29:101 activity in NO bioassay system 29:101 from Rabdosia excisa 15:171 from Rabdosia inflexa 15:172 from Rabdosia umbrosa 15:175 from Rabdosia umbrosa var. hakusanensis 15:175 from Rabdosia umbrosa var. latifolia 15:175 from Rabdosia umbrosa var. leucantha 15:175 Kameda 29:481 validamine synthesis by 29:481 Kampanols 24:449-450 biological activity of 24:450 structures of 24:449 Kampo medicines 24:875-926 active compounds of 24:878 anti-angiogenesis action of 24:875-925 anti-hyperglycemic action of 24:875-925 anti-inflammation action of 24:875-925 anti-proliferation action of 24:875-925 blood glucose regulatory action of 24:875-925 blood vessel contraction of 24:875-925 blood vessel relaxation of 24:875-925 chemical-structure-activity of 24:875-925 neuromuscular blocking action of
24:875-925 pharmacological activity of 24:875-926 smooth muscle contraction of 24:875-925 smooth muscle relaxation of 24:875-925 Kanamycins 14:144;20:714 Kanedelia candel 7:180,181,183,184, 194,195 Kanerin 9:293,294 Kanerodione 9:293,294 Kanerol 9:293 Kaneroside 9:293,294 Kanglemycin 23:54 Kanglemycin A 23:59 Kansuinine B 2:262,264,266 Kanzonol B 28:229 biological activity of 28:229 Kanzonol G 28:229 biological activity of 28:229 Kanzonol H 28:229 biological activity of 28:229 Kanzonol P 28:229 biological activity of 28:229 Kanzonol R 28:229 biological activity of 28:229 Kanzonol S 28:229 biological activity of 28:229 Kanzonol U 28:229 biological activity of 28:229 Kanzonol V 28:229 biological activity of 28:229 Kanzonol W 28:229 biological activity of 28:229 Kanzonol X 28:229 biological activity of 28:229 Kanzonol Y 28:229 biological activity of 28:229 Kaposis sarcoma 2:421 Kappa receptors 22:24 Kappa-carrageenan 26:1148 Karachicine 2:180,181 Karacoline 25:528 Karakin 27:522 Karamatsu 20:613 Karamatsuic acid methyl ester 29:99 activity in EBV assay system 29:99
454
Karatavic acid 1:660,662 from Ferula karatavika 1:660 synthesis of 1:660-662 cis-Karenin 9:295,296 trans-Karenin 9:295,296 Karounidiol 25:61 Karpluspople expression 17:552 Karvi 23:652 Karviskione 20:277 Karwinskii 22:555,583,585,586,589, 591-592,600 Karwinskii calderonii 22:556,560,589 Karwinskii humboldtiana 22:556,558, 559,563,570,572,577,583,585-590, 600 Karwinskiijohnstonii 22:556,559,572, 578,585,589 Karwinskii latifolia 22:556,583,589 Karwinskii mollis 22:556,559,572,589 Karwinskii parvifolia 22:56,559,562, 563,567,573,577,583,588,589,592, 593,596,600 Karwinskii rzedowskii 22:556,559,589 Karwinskii subcordata 22:556,559,572, 589 Karwinskii tehuacana 22:556,559,570, 571,589 Karwinskii umbellate 22:556,559,570, 572,588 Karwinskii venturae 22:556,559,589 Kassinin (KAS) 27:800 Kasugamycin 23:343 (-)-Katihinol L 25:856 Kato's synthesis 12:181,182 of seco-taxane 12:181,182 KATpchannels 25:534 Katsuki-Sharpless epoxidation 12:324, 481 Kauniolide 7:235 ent-Kaur- 16-en- 19-oic acid 29:100 activity in NFkB bioassay system 29:100 activity in EBV bioassay system 29:100 (-)-Kaur-16-en-19-oic acid 9:396,397 ent-Kaur-16a-ol-19-oic acid 26:811 ent-Kauran-1613,17-diol 15:172 from Rabdosia glutinosa 15:172 ent-Kauran- 16-en- 19-oic acid 26:811
8,9-seco-ent-Kaurane 15:162 (-)-Kaurane 19:387 ent-Kaurenic acid 30:713 structure of 30:713 Kaurane 9:271;25:241,246 6,7-seco-ent-Kaurane skeleton 15:136, 162 Kaurane skeleton 19:387 6,7-seco-ent-Kauranes 15:112 Kaurane-type diterpenes 14:546 enantioselective synthesis of 14:546 ent-Kaurenate 27:305 ent-Kaurene 15:16,135 ent-Kaurene glycoside 15:16-18;27:14, 22 from Stevia rebaudiana 15:16-18 suavloside A 27:14,22 suavloside B 27:14,22 suavioside G 27:14,22 suavioside H 27:14,22 suavloside I 27:14,22 suavloside J 27:14,22 Kaurene-type diterpenoids 2:280 Kaurenoic acid 6:186;25:242 GA12 aldehyde from 6:171,172 6,7-seco-ent-Kaurenoid diterpenoid 15:136 ent-Kaurenoids 15:112 8,9-seco-ent-Kaurenoids 15:112 ent-Kaurenol 30:713 structure of 30:713 Kawada's synthesis 30:30-33 of (-)-pironetin 30:30-33 Kawain 22:540,529 Kawin 13:660 from Piper methysticum 13:660 Kazinol A 28:17 antioxidant activity of 28:17 as tyrosinase inhibitor 28:17 as platelet aggregation inhibitor 28:17 Kazinol B 28:17,226,230 anti-human immunodeficiency virus (HIV) activity of 28:226 as cyclooxygenase 28:17 as platelet aggregation inhibitor
455
28:17 biological activity of 28:230 Kazinol C 28:210 from moraceous plants 28:210 Kazinol E 28:210 from moraceous plants 28:210 Kazinol F 28:16,210,230 antioxidant activity of 28:16 as tyrosinase by inhibitor 28:16 biological activity of 28:230 from moraceous plants 28:210 Kazinol J 28:210 from moraceous plants 28:210 Kazinol M 28:210 from moraceous plants 28:210 Kazinol N 28:210;28:230 from moraceous plants 28:210 biological activity of 28:230 Kazmaier's modification 26:1227 of Ireland-Claisen rearrangement 26:1227 KB activities 20:81 KB cells cytotoxicity assay 30:733 determination of cytotoxic activity 30:733 KB-1 28:229 biological activity of 28:229 KB-3 28:229 biological activity of 28:229 KB-16 (human oral epidermal carcinoma) 30:588 activity of (-)-deoxypodophyllotoxin against 30:588 activity of (-)-yatein against 30:588 K-cells-IL2-activated killer cells 25:273 effect of Actinoplanes sp. 25:777 KCI-depolarized rat portal vein 30:748 KDG 30:441,431 from glyceraldehyde 30:431 KDN 30:421,422,433,440,444,448,462 configuration of 30:463 conversion of 30:462 from membrane polysialoglycoproteins 30:422 from non-carbohydrate sources 30:462 from oxalacetic acid 30:433
from rainbow trout eggs 30:422 in cancer cells 30:422 in human fetal card red blood cells 30:422 oncotetal antigen properties of 30:422 preparation of 30:440 structure of 30:421 KDO 13:207,210;30:421,441,449, 465,471 Aug6 synthesis of 30:465 debenzylation of 30:441 hydrogenolysis in 30:441 intramolecular cyclization of 30:441 modifications of 30:465 Pettus synthesis of 30:471 synthesis of 30:441 via cobaltoxime 30:449 structure of 30:421 KDO analogs 30:430 synthesis of 30:430 KDO derivative 30:433,438,455 anomeric mixture of 30:433 KDO synthesis 30:448,450,456 photochemical 30:448 radical cross-coupling in 30:448 radical elongation process in 30:450 via exo-glycals 30:456 Keck DCC protocol 26:1230 Keck method 11:157 Kedarcidin 25:796 Kedarcidin chromophore 25:797 Kedde reagent 19:753 Keenamide A 25:887,888;28:652 as cyclic hexapeptide 28:652 as cytotoxic agent 28:652 Kelly procedure 10:111 Kemebakaurin 15:135 Kende 29:380,384 steganes synthesis by 29:380,384 Kent method 6:386 Keramadine 21:68 Keramakide D 23:220 Keramamide A 23:220 Keramamide B 23:220 Keramamide C 23:220 Keramamide F 23:220
456
Keramamide K 26:1183 Keramamide L 26:1183 Keramamides 25:885 Keramamides B-J 26:1181-1183 Keramamides F 25:884 Keramamides G 25:884 Keramamides H 25:884 Keramamides J 25:884 Keramamides K 25:884 Keratinocytes 12:393 by staurosporine 12:393 tumor promoter in 12:393 Kermesic acid 20:768 Kerriamycin 5:596 isotetracenon antibiotic 5:596 ' Kerriamycin A 5:596 (+)-Kessane 14:365 Ketal 8:160 trans-Ketalization 4:8,9 acid catalyzed 4:8,9 Ketalization 6:73,82,83,85 regioselective 11:41,42 Ketalized Diels-Alder type adducts 17:458 Ketamine 18:680 Keten acetals 4:357 Diels-Alder reaction with 4:357 Ketene complex 16:406 Ketene dithioacetal derivative 12:156,157 preparation of 12:156,157 Ketene dithioacetal S,S-diozides 6:733 synthesis of 6:33,334 Ketene silyl acetals 4:463,464 Ketene-imine cycloaddition 4:440,470472,474 1,2-diastereoselection 4:472 in Bose reaction 4:440,470 Ketenylidene-triphenylphosphorane 4:569,572 ec-Keto acetals 14:500,501 diastereoselective reduction of 1:622 from (-)-(2S,3S)- 1,4-dimethoxy2,3-butanediol LiAIHareduction of 14:500,501 Michael addition of 14:500,501 with methyl addition of 14:510
~-Keto acetals 14:497-499 addition of organometallic reagents to 14:497-499 diastereoselective 14:497,498 from (+)-(2R,3R)- 1,4-dimethoxy2,3-butanediol 14:497-500 from (R, R)-2,4-pentanediol 14:497,499 LiAIH4-reduction of 14:499,500 NaBH4-reduction of 14:500 13-Keto acid 8:384 ;25:165 decarboxylation of 8:297 trans-f3-Keto ester 4:437 from azetidinone 4:437 [3-Keto esters 4:436,439 in asymmetric hydrogenation 4:439 13-Keto thioester 11:195 reduction of 11:195 2-Keto-3-deoxy-6-phosphogluconate (KDPG) aldolase 30:424 structure of 30:424 2-Keto-3-deoxy-gluconate (KDG) aldolase 30:424 structure of 30:424 3-Keto-4c~-H-germacran- 1(10), 11( 13)dien-6,12-olide 27:563 4-Keto-5-methyl-trans-decalins 9:30 2-Keto-8 c~-hydroxy-5c~,6cx,7 ~H- guaian1(10),3 (4), 11( 13)-trien-6,12-olide 27:580 [3-Ketoacyl-ACP reductase 22:265 dehydratase (DH) 22:265 [3-Ketoacyl-ACP synthase 22:265 3-Ketoadociaquinone A 17:33;25:861 ot-Ketoamide 11:286 from aminoketal 11:286 [3-Ketoamide 12:162;25:785 asymmetric hydrogenation of 12:162 4-unsubstituted [3-1actam from 12:162 cx-Ketobutyric acid 13:319 Ketocarotenoids 21:305 Ketoconazole 22:60 Ketodeoxoscalarin 17:10 3-Ketodociaquinone A 25:862 3-Ketoepitaondiol 17:8
457 [3-Ketoester 6:429,430;14:652,653 [3-Ketoester enolization 14:734 c~-Ketoglutaric acid 9:542,543,553 c~-Ketogluturate 26:638 4-Ketoheptanolide 19:422 Ketohexopyranose nucleosides 4:248-253 5-Keto-imine intermediate 6:480,481 benzodiazonin-3-one from 6:480,481 7-Ketoisodrimenin 20:469 7-Ketoisodrimenin-5-ene 20:469 bis-c~-Ketol astaxanthin 6:152,153,161 cx-Ketol rearrangement 11:53,54 Ketolactam 6:510-513,602 ellipticine derivatives from 6:510,511 Ketologanin 7:470 cx-Ketols 27:72 y-Ketols 27:72 ent- 13-epi-Ketomanoyl oxides 25:260 Ketone 5:782,783 formation by epoxide rearrangement 5:782,783 Ketone reduction 1:415,417 Luche's conditions 1:415,417 stereoselective 1:415,417 to equatorial alcohol 1:415,417 with axial hydride attack 1:413, 415 with NaBHa-CeC13 1:413,419 Ketonucleosides 19:512 biological activity in 4:253 synthesis of 19:512 3'-Ketonucleosides 19:513 Ketopelenolide 27:564 Ketopelenolide A 7:231 6-Keto-PGFza 25:595 Ketophosphonate 6:275-277 from lithiomethylphosphonate 6:276 macrolide from 6:276,277 (1S)-Ketopinic acid 12:417 from (-)-camphorsulfonic acid 12:417 Ketopinic acid 12:417 reduction of 12:417 4-subsituted 2-oxazolidinones
from 12:416,417 with L-Selectride 12:417 (+)-trans-Ketopinic acid 4:640,641 3-(IS)-Ketopinyl-2-oxazolone 12:419-422 methoxybromination of 12:419-422 methoxyselenylation of 12:421,422
trans-5-bromo-4-methoxy
derivatives from 12:419-421 reversed zt facial selection in 12:419-422 Ketoprofen 6:323 3-Ketopropyl- 19R-heyneanine 9:171 2-Ketopupukeanone 6:82 (+)-2-isocyanopupukeanane from 6:82 Ketopyranose nucleosides 4:248 3-Ketoreductase 19:648 Ketoreductase 25:501 Ketoresorcinol 19:226 19-Keto-soyasapogenol B 25:184 A-nor-Ketosteroid 2:163 A-seco-6-Ketosteroid 2:169 Cotton effect of 2:169 N-Keto-stypodiol diacetate 25:591 Ketosugars 4:353,354 Grignard reactions with 4:353, 354 f3-Ketosulfoxides 4:502 reaction with enolate anions 4:502 reduction of 4:502-504 synthesis of carbohydrates 4:504-512 synthesis of macrolides 4:513-512 3-Ketotrichothecene 6:229 3cx-hydroxytrichothecene from 6:229 reduction of 6:229 8-Ketotrichothecenes 6:230,231,234, 235 Ketotriol asadanin 17:369 Ketourethane 12:303 11-Keto-fl-boswellic acid 22:128
458 cx-Keto-[3,y-unsaturated acetal 14:496 addition of Grignard reagents 14:496 Kexin 25:390 Kexin-like subtilases 25:389,390 Khan's method 21:742 for synthesis of chalcone 21:742 Khaya grandifoliola 5:700 Khaya ivorensis A. 22:524 for convulsions in children 22:524 Khaya senegalensis A. 22:524 for convulsions in children 22:524 KHMDS 22:229 Khusimone 3:32 synthesis of 3:32 (+)-Khusimone 4:674 Kibayashi' s group 29:432 marine alkaloids synthesis by 29:432 Kidamycin "aglycone" 11:136 antitumor antibiotics 11:136 O-methyl derivative of 11:137 1-oxabenz [a] anthracene 11:136 synthesis of 11:135-139 Kidney disorders 26:50 Herniaria hirsuta in 26:50 Kidney disturbances 30:207 use of Phyllanthus (genus) in 207 trans-Kielcorin B 26:259 Kievetone 25:546 Kigelia africana 7:406 Kigelia pinnata 23:342;29:747 Kiheisterone C 25:795 Kijanimicin 19:118 L-Kijanose 19:118 Kikumycin 5:553,554 Kikumycin B 5:553 Kinesin motors 25:695 inhibitor of 25:695 Kinetic characteristics 27:350 ofisomerization process 27:350 Kinetic deprotonation 11:337,338 of 2 cycl0hexen-l-one 11:337, 338 of enone 11:368 Kinetic isotope effect 7:56,57
Kinetic parameters 7:65,66;27:351 ofcellobiose analogues 7:65,66 of lactose analogues 7:67.68 of methyl [3-gentiobioside 7:52 of methyl [~-lactoside 7:52,54 of phenyl [3-D-glucopyranoside derivatives 7:55,56 Kinetic resolution 1:508,698;3:23, 19:478 by Sharpless epoxidation 4:342 of secondary 2-furylcarbinols 19:478 under Sharpless epoxidation conditions 19:478 Kinetic studies 27:857 of cell 27:857 Kinetin 26:640 Kinetin (6-furfurylaminopurine) 7:90 Kinetoplastid flagellates 2:298 polysaccharides as markers 2:298 Kingiside 16:307 from Lonicera morrowii A. Gray 16:307 Kinin formation 30:204 inhibition of 30:204 Kinin system 22:115 Kinoprene 13:667 Kirby reaction 8:76 Kirk-Petrow reaction 10:409 Kirschsteinin 22:72 Kishi synthesis 13:436-442,443,457, 458,461 of mitomycins 13:4-10,25,26,29 Kishi's retrosynthesis 26:1231 of onnamide 26:1231 Kishi's rule 1:404,130,163,167,168,171, 175;4:178,181,183,184,188,197,202, 203,705 Kishi's-model 4:503,504 Klaineanone 11:74-76 synthesis of 11:74-76 Klebsiella 12:63;26:1155 Klebsiella aerogenes 26:1263,1269 Klebsiella pneumoniae 5:106,308,325; 12:400;20:712;23:136,474 ;25:258, 259;26:402 Klemer fragmentation 3:201,202
459
Klemer-Rhodomeyer reaction 1:510, 511 Kloechera corticis 25:143 Kloeckera africana 5:283 Kloeckera magna 1:283,701 in microbial reduction 6:13 Kluyveromices sp. 13:302 Kluyveromyces fragilis 26:338 Kluyveromyces lactis 26:1127 Klyne's rule 26:8 of molecular rotation 26:8 Klyne-Hudson rule 15:207 Km values 30:95 oflipase activity 30:95 Knapp and Sharma 29:214 miltirone synthesis by 29:214 Knema elegans 21:591 Knemidocoptes pilae 28:415 Knoevenagel condensation 6:53,67,68, 316,320,328,331,334;24:36,37 in 14-epi-upial synthesis 6:67,68 Knoevenagel condition 11:140 Knoevenagel cyclisation 9:341 Knoevenagel reaction 13:109 Knoevenagel-Doebner condensation 24:717,718 Knoevenagel-type reaction 7:475 KO 30:421 structure of 30:421 Kobophenol A&B 26:535,558,560,561 Kobusin 26:200,231 Kochia prostrata 22:524 Kochia scoparia 24:273 Kocienski-Lythgoe condensation 4:602, 603 Kocienski-Lythgoe-Julia olefination reaction 11:393-395 Kodo-cytochalasin-1 and 2 15:353 Koelreuteria henryi 27:842;29:581 Koenigs-Knorr condensation 3:199 modification of 3:199 Koenigs-Knorr coupling (AgzCO3AgCLO4) 1:419,420 Koenigs-Knorr procedure 10:571 Koenigs-Knorr reaction 6:395;8:206, 258,359,363 Koenigs-Knorr synthesis 10:466 Koga 29:386 steganes synthesis by 29:386
Koga's method 11:241,242 of asymmetrization 11:241,242 of ~-symmetric ketones 11:241,242 Koidzumiol 7:218 Kojic acid 12:269;21:587 O-alkylation of 12:269 with allylic bromide 12:269 [4+2] cycloaddition of 5:799 from Taxus mairei 20:118 Kokoona zeylanica 5:743-745;30:642, 674 celastrahydride from 30:642 D:A-friedo oleananes from 7:147-149 phenolic triterpenes from 7:147-149 triterpene quinone methide from 7:147-149 Kokoondiol 5:744-746,147,148 Kokoonol 7:147,148 3,27-diozy derivative 5:745 3,21,27-trioxy derivative 5:745 Kokum soap 23:656 Kokusagine 21:68 Kokzeylanol 5:744-746,147,148 Kokzeylanonol 7:147,148 Kolavenic acid 6:28 agelasin B from 6:28 from Solidago species 6:28 Kolbe reaction 9:371 Koltin 22:62 Komaroine 14:762 from Nitraria komarovii 14:762 Komarovicine 14:762 from Nitraria komarovii 14:762 from quinoline-8-carboxaldehyde 14:763 komarovidine from 14:763 komarovine from 14:763 synthesis of 14:763 via Pictet-Spengler reaction 14:763 Komarovidine 14:758,763,764 biosynthesis of 14:763,764 from komarovicine 14:763 from Nitraria komarovii 14:762 from quinoline-5-carboxylic acid 14:763
460
synthesis of 14:763 via Bischler-Napieralski condensation 14:763 Komarovine 14:763,764 biosynthesis of 14:763,764 from komarovicine 14:763 from Nitraria komarovii 14:762 Komarovinine 14:763,764 biosynthesis of 14:763,764 from Nitraria komarovii 14:762 from quinoline-6-carboxaldehyde 14:763 synthesis of 14:763 via Pictet-Spengler reaction 14:763 Komayum 23:655 Kombamide 26:1184 Konbuacidin 25:798 Konbuacidin A 25:711,798 Konevenagel-type reaction 11:139 K6nigs-Knorr coupling 21:170 Koningic acid 21:229 Konjac glucomannan 26:1149 Kopsia dasyrachis Ridl. 21:128;29:363 kopsirachin from 21:128 Kopsidasinine 5:53,9:188,189 Kororamels 25:902 Korundamide A 26:822,823 Korupensamine C 20:449,451 from Ancistrocladus kerupensis 20:447 ent-Korupensamine D 20:440 Korupensamines A and B 20:443,451 from Ancistrocladus kerupensis 20:442 Koshikamide A 26:1193 Kotalagenin 16-acetate 30:645 ~3C NMR data of 30:645 ~H NMR data of 30:645 HMBC spectrum of 30:645 NOESY spectrum of 30:645 stereochemistry of 645 structure of 30:645 Koteconazole 2:423,441 Koumicin N-oxide 15:466,467 Koumicine 15:466,467 19(E)-Koumidine 15:466,467 from gardnerine 15:469
Koumine 15:475,476 from Gelsemium elegans 15:475,476 Koumine Nb-oxide 15:475 from Gelsemium elegans 15:475 Koumine-type alkaloids 15:475-477, 500-503 synthetic studies of 15:500-503 Kouminol 15:475 Kozikowski approach 12:20-22 for avermectin oxahydrindene subunit 12:20-22 Kozikowski's nitrile oxide 12:21,22 Kozikowski's retrosynthetic analysis 13:588 kP6 preprotoxin 25:389 Krameria triandra 26:204 scavenging activity of 26:204 Krapcho decarboxylation 18:246 Krapcho's thermal dealkoxycarbonylation 24:39 cx-Kratin 26:667 Kraus method 6:225,226;11:129 Krebs cycle 7:112,117,387;26:924,940 Krebs cycle enzymes 11:197 Krebs tricarboxylic acid cycle 6:252 Kresoxim methyl 22:250 Krohncke reaction 20:602 Krohncke's procedure 6:513 Krow 29:384 steganes synthesis by 29:384 Krukovine A 23:693 Krukovine B 23:693 Krukovine C 23:693 Krukovine D 23:693 Krukovine E 23:693 Kryptogenin 5:774 KSD assay 25:862 KT-5720 12:384-386 KT-5822 12:384-386 KT-5926 12:388 myosin inhibitor of 12:388 protein kinase inhibitor of 12:385,386 Kuanoniamine alkaloids 21:285 Kuanoniamine B 23:272 Kuanoniamines A-D 17:23;25:893,894, 995 Kuanoniamines C,D 21:269,220
461 Kudzusapogenol A 25:95 Kudzusapogenol A glycoside 25:103, 105 Kudzusapogenol B 25:97 Kudzusapogenol C 25:96 Kudzusaponln Ai 25:95 Kudzusaponln A2 25:95,104 Kudzusaponln A3 25:95,104 Kudzusaponln A4 25:95,104 Kudzusaponm A5 25:95,104 Kudzusaponm C~ 25:96,103 Kudzusaponln PA3 25:118 Kudzusaponln SAI 25:95 Kudzusaponln SA2 25:104 Kudzusaponln SA3 25:95 Kudzusaponln SA4 25:104 Kudzusaponm SB1 25:95 Kuehneromycin A 29:128,129 absolute stereochemistry of 29:129 effect on reverse transcriptases 29:128 related natural compounds 29:129 synthesis by Jauch 29:159 synthetic strategies of 29:129, 130 total synthesis of 29:148 transition states in synthesis of 29:161 Kuehne's synthesis 14:831-849 ofvinblastine 14:831-849 of vincristine 14:831-849 Kuepaloxane 25:787 Kuhn-Roth oxidation 11:210 Kulactone 9:300,305,308 Kumatakenin 28:226,229 anti-human immunodeficiency virus (HIV) activity of 28:226 biological activity of 28:229 Kumusine 26:1201 Kupffer celts 25:464,475 Kurarmine 9:150 Kurilogenin 7:280 from Duasmodactyla kurilensis 7:279 Kuriloside A 15:89 from Duasmodactyla kurilensis 15:89
Kurospongin 5:371 Kutney's synthesis 14:806-821 ofvinblastine 14:806-821 ofvincristine 14:806-821 Kuwajima's B-ring cyclization route 12:190 Kuwanon 28:212 biological activity of 28:212 Kuwanon C 28:210,230 biological activity of 28:230 from moraceous plants 28:210 Kuwanon E 28:210 from moraceous plants 28:210 Kuwanon G 17:451 ;28:201,209,221, 230 biological activity of 28:230 biosynthesis of 17:165 bombesin receptor antagonist of 28:221 from moraceous plants 28:201 hypotensive action of 28:209 optical rotation of 17:464 Kuwanon H 28:200,201,209,212,221, 222,223,225 anti-human immunodeficiency virus (HIV) activity of 28:226 as bombesin receptor antagonists 28:223 as GRP-induced DNA synthesis inhibitor 28:222 biological activity of 28:212 bombesin receptor antagonist of 28:221 from moraceous plants 28:201 hypotensive action of 28:200, 209 Kuwanon L 28:210 from moraceous plants 28:210 Kuwanon M 28:210,212 biological activity of 28:212 from moraceous plants 28:210 Kuwanon R 28:230 biological activity of 28:230 Kuwanons J 17:455 Kynurenic acid 26:965-968,970 Kynurenine 21:70;26:966,968-971,990, 998 Kyurenic acid 25:529
462
L-1210 leukemia cell 21:403,414 L-653,150 26:242 as PAF-induced inhibitor 26:242 Labd- 13(E)-en-8a, 15-diol 25:267 (E)-Labda-8(17), 12-diene- 15,16-dial 23:809 Labda-8(17), 13-dien- 15,12R-olid- 19-oic acid 29:101 activity in EBV bioassay system 29:101 (+)-Labda-8(20), 13-dien- 15-oic acid 6:56,57,111,117,120,125 (E)-8(17), 12-Labdadiene-15,16-dial 23:801 Labdadiene- 15,16-diol 11,15-hemiacetal (11-OH-8(17),12(E)-) 25:266 8(17), 12(E)-Labdadiene- 15,16-diol 25:265,266 Labdadienoic acid 25:248 5R, 8R,9R, 10R-Labdan- 13(6)-ene-8d, 15diol 25:258 Labdan-8(17), 13-dien-3fl- 15,18-triol 25:251 ent-Labdane 15:252;25:251 ent-Labd-8,13(E)-dien- 15-ol 25:249 ent-Labdane oxides 25:249 Labdane 25:241,244,256,259,261,266, 275,276,277 activities of 25:257 Labdane 13-O-glycosides 25:251 Labdane diterpenes 23:810 Labdane diterpenoids 1:662 Labdane F2 29:102 activity in PLA bioassay system 29:102 Labdane glycoside 25:251;27:14,22,24 baiyunoside 27:14,24 gandichandioside A 27:14,25 phlomisoside I 27:14,24 Labdane S 25:246,249 Labdane xylosides 25:252 Labdanes 10:408 Labdane-type diterpenoids 20:691; 21:692,721 Labdanum oil 25:253 (+)-(13E)-13-Labdene-8,15-diol 1:671, 672 Labiatae 7:96,118-120;21:605;25:921
Labiatae pinaceae 27:361 Labopghora variegata 25:729 Labophorins A and B 25:729 Laburnine 1:248,339 synthesis of 1:248,339 Lacarol 7:224 Laccaic acid C 20:277 Laccol 9:319 Lachnanthes tinctoria 4:618 Lachnanthocarpone 17:372 Lachnanthocarpone formation 4:618 Lachnates 17:372 Lachnella 26:462 Lachnophyllum ester 7:221 Lachnum papyraceum 25:781,785; 26:446 Lachnumol 25:785 Lachnumol A 26:446,447 Lachnumon 25:781,782 Lachnumore 25:757 Lacinartin 7:204,205,224 Laciniata furanone 9:532,533 Lac-permease 8:353 Lactam 1:325,326 O-methylation 1:325,326 13-Lactam 12:115,159-172;22:245 by 4CC 12:115 from [3-amino acids 12:115 C4-alkylation of 12:159-172 Lactam analogues 12:388 Lactam carbonyl 3:474 selective reduction of 3:474 [~-Lactam compounds 12:155-159 from D-amino acid 12:155-159 synthesis of 12:155-159 Lactam sulfoxide 3:109 cyclization of 3:109 [3-Lactamase 16:727 [3-Lactams 11:706-213 biosynthesis of 11:207-213 Lactams 17:573 170-NMR 17:573 8-Lactams 18:315 synthesis of 18:315 Lactarane 17:154 Lactarazulene 14:315 Lactarius camphoratus 17:156 Lactarius chrysorrheus 17:196
463
Lactarius circellatus 17:197 Lactarius controversus 17:198 Lactarius deceptivus 17:198 Lactarius deliciosus 17:198 Lactarius deterrimus 17:198 Lactarius flavidulus 17:198,201 Lactarius fuliginosus 17:153,201 Lactarius fulvissimus 17:200 Lactarius genus 17:153,156 sesquiterpenes from 17:159 Lactarius glaucescens 17:198 Lactarius glutinopallens 17:199 Lactarius glyciosmus 17:199 Lactarius helvus 17:199 Lactarius indigo 17:199 Lactarius lignyotus 17:200 Lactarius mitissimus 17:200;26:461 Lactarius necator 17:199 Lactarius pergamenus 17:198 Lactarius picinus 196,201 Lactarius piperatus 17:197,198 Lactarius quietus 17:196 Lactarius rufus 17:199 Lactarius scrobiculatus 17:153,196,197 Lactarius subvellereus 17:198 Lactarius thejogalus 17:200 Lactarius torminosus 17:196,197 Lactarius vellereus 17:153,196,197 Lactarius, metabolites 17:154 Lactase 10:498 Lactase phlorizin hydrolase 25:609 Lactate 12:223 synthesis of 12:223 (R)-Lactates 8:140 (S)-Lactates 8:140 Lactic acid 2:163;28:386 in honey 28:386 Lactiflorasyne 7:204 from Artemisia lactiflora 7:203 X-ray analysis of 7:203 Lactiflorenol 7:218 from Artemisia lactiflora 7:218 Lactobacillus helveticus 13:319 Lactobacillus plantarum 23:474 Lactobocillus sp. 25:257,924,927,928 Lactoferrin 22:327 [3-Lactoglobulin 30:840 Lactol 11:140,141
Lacto-N-biose I 10:459,461,467-471, 476 synthesis of 10:474,475 Lacto-N-biose II [GlcNAcl3(1-3) Gal] from oxazoline 10:474,475 y-Lactone 17:270;19:470 reduction of 19:470 Lactone 30:17,457 hydroboration-oxidation reaction of 30:457 hydrogenation of 19:469 methylation of 19:469 synthesis of 30:17 (4S,5S)-Lactone 8:296 S-Lactone 8:298,306 syn addition of 8:306 (4R)-Lactone 8:305,306 anti addition of 8:305,306 Lactone annulation 13:29-31 Lactone Claisen rearrangement 13:544, 596 Lactone methyl-isomerase 8:300 Lactone rearrangement fragmentation 3:96 Lactone synthesis 13:615-626 asymmetric synthesis of 13:621, 622 Lactone triflate 10:60 ring contraction reaction 10:605 to oxetane-2-carboxylate 10:605 Lactone unit 11:345-347 construction of 11:345-347 model studies on 11:345-347 of compactin and mevinoline 11:345-347 2,3-seco-22,29-Lactone-oleane- 12-ene2,3-dioic acid 3-methyl ester 30:650 structure of 30:650 5-Lactones 10:218 Lactones 3,157,171;10:385-388;14:557, 558 CD of 2:171 saturated 17:275 synthesis of 3,157,171; 10:385-388;14:557,558 unsaturated 17:27I via intramolecular hetero-DielsAlder reaction 14:557,558
464
Lactonisation 12:157,158 acid-catalyzed 12:157,158 by Gerlach's procedure 6:542, 543 of N-acetyl muramic acid 6:389, 390,395 of co-hydroxy-acids 8:233 with pyridinium acetate 11:84,85 Lacto-N-iso-octaosyl ceramide 10:461 Lacto-N-neo-hexaose 10:478,480 by double glycosylation 10:478 Lacto-N-neo-tetraose 10:462 from oxazoline 10:478 Lacto-N-tetraose 10:468 from Lactobacillus bifidus 10:468 Lactoperoxidase 19:455 Lactoquinomycin 11:128 Lactosamine 10:462 N-acetylation of 10:462 catalytic hydrogenation of 10:462 from 3-O-13-D-galactopyranosylD-arabinose 10:463 from D-lactal hexaacetate 10:464 from lactose 10:462-466 from monosaccharides 10:466,467 synthesis of 10:461,467,471 Lactosaminoglycan 10:460 Lactose 1:508,509,499 Lactose analogues 7:67,68 Lactosylceramide 18:796 N-(S)-Lactoyl-(S)-proline 13:482 Lactuca sativa L. 26:187;27:215,217 allelopathic interaction of 27:215 Lactuca virosa 20:8 Lactucin 20:8 Lactucopicrin 20:8 16-Oxo-8(17), 12(E)-Ladadiene- 15-oic acid 25:266 Ladenburg prism mechanism 7:362,263 Ladybird alkaloid 6:447 Laetisaria arvalis 21:187 Laetisaric acid 21:188,189 Laevigatoside 7:293 from Linckia laevigata 7:290 Laeviuscolosides F,G,H and I 15:64
Laevoglucosan 1:453 Lagascatriol 29:103 activity in COX bioassay system 29:103 activity in NO bioassay system 29:103 Lagenaria leucantha 29:615 Lagenidium callinectes 22:79 Lagerstoroemia 23:405 Lagerstroemia subcostata Koehne 1:368 Lagochilus sp. 22:524 Laguncularia racemosa 7:175 Lahoramine 1:207 synthesis of 1:207 Lahoricine 5:125,158,159 Lahorine 1:207 Lamalbid 7:471 Lambertianin A 23:416 (+)-Lambertic acid 10:407,640-642 synthesis of 14:640-642 Lamellariidae 17:21,22 Lamellarins A-D 17:22 Lamellarin A 23:248 Lamellarin B 23:248 Lamellarin C 23:248 Lamellarin D 23:248 Lamellarin E 23:248 Lamellarin F 23:248 Lamellarin G 23:248 Lamellarin H 23:248 Lamellarin M-triacetate 23:250 Lamellarin N 23:249 Lamellarin O 23:246 Lamellarin P 23:246 Lamellarin Q 23:246 Lamellarin R 23:246 Lamellarin T 23:249 Lamellarins 25:706 Lamellomorpha strongylata 26:1189 Lamiacea 21:584 Lamiide 7:463 acid rearrangement of 7:463 aglycone 7:463 Lamiide aglycone 7:475 reduction of 7:475 Lamiidol 7:467 Laminaceae 25:171
465
Laminarabiose 8:349 hydrolysis of 8:349 Laminaran 26:1121 from brown algae 26:1121 Laminaria abyssalis 30:400 sulphated polysaccharide (PS) from 30:400 Laminariajaponica Aresch. 30:56 fucoidan from 30:56 in arteriosclerosis treatment 30:56 in cancer treatment 30:56 in hyperlipidemia treatment 30:56 Laminaria ochroleuca 22:524 Laminaria pedicularioides 25:868 Laminaria sp. 25:724;26:1121 Laminariales 26:478 Laminin a~ 27:806 Laminine 26:478 (-)-Laminitol 18:434 Lamiol 7:440,455,459,460,464-466 Lamiol aglycone 7:475 reduction of 7:475 Lamium 26:392 Lamivudine 24:488 as anti-viral agent 24:488 Lamorouxia multifida 24:839 glucoside iridoid of 24:839 Lamorouxia rhinanthifolia 24:839 Lamorouxia sp. 24:839 Lamotrigine 22:507 (+)-Lamprolobine 18:367 Lampteromyces 29:271 Lampteromyces japonicus 26:706 Lanatoside A-E 15:362 Lancerodiol 5:724,725,731 p-methoxybenzoate of 5:724, 725,731 Lancerotriol ester 5:732 Lancet-shaped follicular mites 28:410 as cause of demodectic mange 28:410 Langmuir-Blodgett films 25:334 Lankacidin 21:316 Lankaumycin 4:255 Lanoslane 25:49,57 Lanosprazol 25:612 Lanost-9(11)-ene 27:468
Lanostane 9:267,302 16a-Lanostane carboxylic acids hydroxydehydrotrametenolic acid 25:57 Lanostane triterpenes 22:105,117 Lanostanes 25:61 O- 16a-hydroxytrametenolic acid3-acetate 25:61 pachymic acid 25:61 poricoic acid B 25:61 abiesonic acid methyl ester 25:64 Lanostene triterpenes 10:151 Lanosterol 7:266;21:314;22:59,255 Lanosterol ester 9:467 Lanosterol glycosides 21:644 Lansic acid 1:658-660 synthesis of 1:658-660 Lansiolic acid 1:648-660 synthesis of 1:648-660 Lansioside A,B,C 1:658 Lansium domesticum 1:658 Lantadene A 25:64 Lantadene B 25:59,64,66 Lantadene C 25:59 Lantana camara L. 22:524;23:487,521, 523 ;27:377,836,29:586 as anticonvulsant agent 22:524 polar constituents from 23:523 Lanthella 25:719 Lanthella basta 10:632 bastaxanthins from 6:150 Lanularic acid 2:287,288 Lapachol 27:851 ;29:734;30:317 biosynthesis of 734 [3-1apachone (21) 27:851 teratogenic potential of 30:317 Lapachol methylether 26:66 [3-Lapachone 27:851 Lapachone 30:310 structure of 30:310 Lapachone antitumor effects 29:744 against A549 human breast cancer cell 29:745 against Cdc25 phosphatases 29:745 against DNA topoisomerase 29:746 against human cancer cell lines
466
29:744 against ovarian adenocarcinoma 29:744 via DNA modification 29:745 of 2-methyl-(Z)-4-phenylimino) naphth[2,3-d]oxazol-9-one 29:744 proteasome inhibition by 29:746 through multistage carcinogenesis 29:746 Lapdap 26:783 Lapidin 5:722,723;29:91 activity in CRG assay system 29:91 Lapidolin 5:722,723 Lapiferine 5:722,723 Lapiferinin 5:722,723 Lapiferol 5:736 ~3C-NMR spectrum of 5:736 isovalerate 5:736 Lapinone 26:803 Lappaconitine 25:528 Lappaconititine 25:528 Lappaol B 5:497,498 c~-1,5-L-arabino-[3-3,6-D-galactan 27:510 Lardoglyphus konoi 1:696;14:487 (-)-lardolure from 14:487 pheromone of 1:696 Lardolure 1:696 from acarid mite 1:696 synthesis of 1:696 (-)-Lardolure 14:487 from Lardoglyphus konoi 14:487 synthesis of 14:487 L-arginineanalogues 25:471 (+)-Lariciresinol 20:620;26:177,188, 205,219 Lariciresinol 26:199 (+)-Lariciresinol 26:219;27:503 as chemopreventive agent 26:219 (+)-Lariciresinol ferulate 20:620 (+)-Lariciresinol p-coumarate 20:620 7S, 8R, 8' R-(-)- Laric ires ino 1-4,4' -bis-O[3-D-glucopyranoside 26:199 Lariciresinol-4[3-D-glucoside 26:199
Larikaempferic acid methyl ester 29:100 activity in EBV assay system 29:100 Larix decidua 17:332 Larix kaempferi 29:99 Larix leptolepis 20:613;26:185 Larmor frequency 9:127,131 Larrea divaricata 17:315 Larrea tridentata 5:9;26:187,205,249 Larreantin 5:9-11 Larus asrgentatus 5:837 hemoglobin components of 5:837 Larus philadelphia 5:837 hemoglobin components of 5:837 Larvotoxic 17:102 Lasallia papulosa 5:311 Lasallia pensylvania 5:311 Lasalocid A 11:196 synthesis of 10:424,715 Laser desorption 9:487 Laser desorption mass spectrometry 5:632,633;25:330,331 Laser Field Desorption (LD) 24:138 of saponins 24:138 Laserpitine 5:725,727,734 Laserpitium halleri subsp, halleri 5:728 Laserpitium latifolium 5:725,727 Lasiantheae fruticosa 5:728 Lasidiol angelate 5:728,729 Lasioderma serricorne (cigarette beetle) 1:695,275 serricomin from 14:275 Lasiodiplodia theobromae 6:557,290, 477 Lasiodiplodin 9:288,289 Lasiodonin 15:172,173 from Rabdosia gaponica var. glaucocalyx 15:172 from Rabdosia macrophylla 15:173 from Rabdosia parvifolia 15:173 Lasioglossumze phyrum 8:222 Lasiokaurin 15:172 from Rabdosia henryi 15:172 from Rabdosiajaponica 15:172 from Rabdosia longituba 15:172
467
from Rabdosia macrophylla 15:172 Lasiokaurinol 15:172 Lasius niger 6:454 Laspeyresia pomonella 26:231 (-)-Lasubine 16:477 synthesis of 16:477 Lasubine I 1:367-370 synthesis of 1:367-370 Lasubine II 1:367 4-epi-Lasubine II 1:368 2-epi-Lasubine II 1:369 (+)-Lat A 25:874 (+)-Lat B 25:874 Lat C 25:875 Lat D 25:875 Lat M 25:874,875 Lat S 25:874,875 "Latent Michael-acceptor" 12:99 Laternula elliptica 25:723 Lathyrus odoratus 26:1268 Lathyrus palustris var. pilosus 25:93 Lathyrus satives 25:529;26:1268 Latrunculi B 25:732 Latrunculia apicalis 18:716;25:708 Latrunculia brevis 9:20;25:822 trunculin-A,B from 9:20 Latrunculia rnagnifica 21:96;25:874; 28:688 6,7-epoxy-latrunculin from 28:689 latrunculin B from 21:96 latrunculin M from 28:689 Latrunculia purpurea 25:760,822 Latrunculia sp. 21:311;25:758,822; 28:685 discorhabdin A from 28:686 Latrunculin A 17:13;19:568;25:733; 28:688 as ichthyotoxins 28:688 2-thiazolidinone moiety of 28:688 Latrunculin magnifica 17:14 Latrunculins 19:550;25:874 Latrunulia monocytogenes 25:450 Lats A and B 25:874,875 Laucopolargonidin 25:653 Laudanine 18:49,73
(+)-Laudanosine 16:506 oxidation of 16:506 S-Laudanosine 16:507 Laudanosine 21:57;22:9;30:564,595, 596 antimalarial activity of 30:595 antiplasmodial activity of 30:596 effect on antiplasmodial activity 30:596 (+)-Laudanosine methiodide 6:475,476 cis-Laudanosine N-oxide 6:468 2,3-benzoxazepine derivative from 6:468 Meisenheimer rearrangement product from 6:468 (+)-Laudanosine N-oxide 6:472 preparation of 6:472 themolysis of 6:472 Laulimalide 19:568;30:5 as microtubule stabilizing agent 30:5 Launaea cornuta 22:524 for epilepsy 22:524 Lauraceae 25:943 Laurales 30:560 order of 30:560 Laurane 9:81 Laurediols 19:454 Laureline 3:424,425 synthesis of 3:424,425 Laurenan 10:232 Laurence genus 25:249 Laurencenynes 19:454 Laurencia brongriartii 25:863 Laurencia concinna 6:24 concinnidiol from 6:24 Laurencia glandulifera 6:63 glanduliferol from 6:63 Laurencia implicata 18:633;26:808,809 brasilane sesquiterpene from 18:633 Laurenciajaponensis 25:803 Laurencia majuscula 6:60 bromochamigrene from 6:60 Laurencia nipponica 6:41,63 (-)-(2R, 6S, 9S)-2,8-dibromo- 9hydroxy-o~-chamigrene from 6:63
468
(+)-isocycloeudesomol from 6:41 Laurencia obtusa 5:363;8:625 brasilenol from 6:6 brasilenol acetate from 6:6 epi-brasilenol from 6:6 Laurencia okamurai 19:454 Laurencia pacifica 6:63 (+)-2-bromo- [3-chamigrene from 6:63 Laurencia perforata 6:29,30,56 Laurencia pinnata 6:9,26;21:252 laurepinnacin from 21:252 Laurencia pinnatifida 5:216,363,81-8 marine sesquiterpenes from 9:81-83 Laurencia poitei 6:35 poitediol from 6:35 Laurencia rigida 25:783 Laurencia saitoi 25:788 Laurencia snyderae 6:6,30 epiguadalupol from 6:30 guadalupol from 6:30 isoconcinndiol from 6:30 Laurencia sp. 5:361-363,368,370; 25:701 ;6:24,59,60;9:8;10:231 (-)-aplysin-20 from 6:24 10-bromo-c~-chamigrene from 6:60 spirobicarbocyclic chamigranes from 6:59 Laurencia subopposita 6:10 oppositol from 6:9 prepinnaterpene from 6:9 Laurencia venusia 5:361 Laurencin 10:201;19:411 total synthesis of 10:202 absolute stereochemistry of 19:422 EI-HRMS of 19:422 IR spectrum of 19:422 isolation of 19:421 Laurenene 3:6,25,61,117;13:19 from Dacrydium cuprassinum 13:19 X-ray crystal analysis of 13:19, 20 Laurenica 25:701 Laurenica majuscula 25:702
Laurenica nidifica 25:702 Laurenica nipponica 25:702 Laurenobiolide 7:231 (-)-Laurenyne 10:225 synthesis of 10:225 Laurenyne 19:411 Lauric acid 21:595 Laurifine 6:477,478 synthesis of 6:477,478 Laurifinine 6:477,478 synthesis of 6:477,478 Laurilia tsugicola 26:703 Laurinterol 17:7 Laurol (7-hydroxy-3,4-epoxy-laurane) 9:81,82,87 Laurolenal 2:170 (+)-Laurotetanine 30:563,564,589,594 activity in human cancer cell line 30:589 activity in murine cancer cell line 30:589 as platelet aggregation inhibitor 30:594 cytotoxic effect of 30:589 N-Lauroylvaline 6:320 synthesis of 6:320 Laurus azorica 26:850 Laurus nobilis 21:599 Laurycolactone A 11:71 Lauryl chloride 6:429 protection with 6:429 N-Lauryl-6-methyl-2-piperidone 6:430, 431 pyrolysis of 6:430,431 Lauthisan 10:213 synthesis of 10:213 (+)-Lauthisan 10:232;19:412,420 synthesis of 10:232;19:412 cis-Lauthisan 10:235 synthesis of 10:235 Lavandula angustifolia 7:94,95,108, 109,118,119,125,126;21:612;27:374; 28:411,412 acaricidal activity of 28:412 essential oil of 28:411 constituents of 28:411 Lavandula latifolia 29:91 Lavandula sp. 7:125;21:617;22:524 Lavandulol 7:126
469
Lavendamycin 3:385 synthesis of 3:387 Lavendustin 15:444-447 Lavendustin A and B 15:445 Lawencia clavidormis 25:770 Lawesson's reagent 3:354,355;8:126, 127 ;10:565 ;12:301,305,322 Lawsone 26:638;29:736;30:314 biosynthesis of 29:736 structure of 30:314 Lawsonia alba 26:837 Lawsonia inermis 30:336 for decoration 30:336 Laxative 30:72 use of Angelica keiskei as 30:72 Laxative activity 30:304-307 of anthranoid compounds 30:304-307 Laxative drugs 30:303 aloes as 30:303 caseara as 30:303 rhubarb as 30:303 senna as 30:303 Laxative effect 30:305 of aglycones 30:305 by damaging epithelial cells 30:305 LC chromatogram 19:771 LC/ESI-MS analyses 28:290 of sulfated tea catechins 28:290 of urinary glucuronid 28:290 LC/MS total ion chromatograms with 29:666 low cost operation of 29:656 of aqueous extracts 29:653 TLC analysis of 29:652 weight distribution in 29:653 L-Camavanine 341 LC-mass spectrometry 21:579 LC-MS 21:555,556.557 LC-MS-MS 21:555,558 LDs0 7:280,284,306 LDL peroxidation 30:224 induction by AAPH 30:224 induction by Cu 2+ 30:224 Leachianol A-G 26:535,555,563,564 Lead tetraacetate 1:439 oxidation of diol 1:439 oxidation of ring C of yohimbine
1:158,439 glucuronide linkage cleavage by 7:156-158 Lead tetraacetate oxidation 5:788 Leaf spot disease 4:601 Leathesia difformis 30:405 Lebistes retculatus 26:689 Leccinum 29:271 Lectins 7:129;24:523,524 inactivation of(HVF) 24:523, 524 Ledebouriella seseloides 22:524 for convulsions and spasms 22:524 Ledol 20:17,19 Ledum palustre 20:17 Leech repellent 5:745 Leepacine 5:150-152 Lefevreiosides A~, A2, C and D 15:96 NO-Leghemoglobin complex 26:937 Legionella pneumophila 13:155 Legislation 13:337-340 Legumes 23:341 Leguminosae 21:3,91,139,611;25:92, 180,186,188,246,248,465;26:637, 871,931 ;27:443,766 saponins from 21:642 Leguminous isoflavone reductase (IFRs) 25:319 Leishma braziliensis 2:311 Leishmania 2:311-314;18:791,793,794; 26:779,780,783,786,789,790,793, 801,803,805,807,808,810,821,822, 824,828,830 glycocomplexes of 2:311-314 polysaccharides of 2:311-314 Leishmania adleria 2:311,313 against kala-azar 2:313 immunity against kala-azar 2:313 Leishmania amazonensis 2:298,794; 23:707 ;26:229,887 amastigotes of 26:828 promastigotes of 26:828 Leishmania braziliensis 29:749 Leishmania decemlineata 26:851859,860,863-866 Leishmania donovani 2:311,312; 21:744 ;25:254,260;26:791,794,797,
470 800,804,805,806,819,821,828; 29:749 glycopetidophosphophingolipid of 2:312 polysaccharides of 2:311,312 Leishmania enrietti 2:314;29:749 carbohydrates in 2:314 Leishmania infantum 21:674;26:810; 29:749 Leishmania major 26:230,784,791,800, 805,810,811 ;29:749 Leishmania mexicana amazonensis 2:314 carbohydrates in 2:314 Leishmania panamensis 21:674;26:821, 822 Leishmania tarentolae 2:298,311 carbohydrates in 2:311,314 Leishmania tropica 21:674;26:802 Leishmania tropica major 2:314 polysaccharides in 2:314 Leishmaniases 2:293;26:781,783, 784,785,793 LELA 29:585 effects on acetyl-11-keto-13boswellic acid (triter-pene) 29:585 Lemieuix oxidation 18:171 Lemieuix-Johnson oxidation 4:592,593; 10:591-592;13:613;18:81 Lemieux-Nagabhushan reaction 14:145 Lemieux-von Rudloff oxidation 1:261-262;6:291,292 Lemmatoxin 7:428 molluscicidal activity of 7:428 Lemmatoxin-C 7:428 molluscicidal activity of 7:428 Lemna bioassay 9:386,387,389,390; 15:344 Lemna gibba 27:330 Lemna minor (duckweed) 9:383,384, 386,387,389,390 Lemnalia africana 25:695 Lemon 23:747 Lemon juice phenolics 23:748 HPLC chromatogram of 23:748 Lendenfeldia chondrodes 25:703 Lennoxamine 1:163,164 synthesis of 1:176,177
Lens culinaris 21:526;26:1263 Lens esculenta 25:93 Lentinan 5:279;25:450;23:115,122,123 antitumor activity of 5:317 13C-NMR spectra of 23:122 Lentinus edodes 5:287,288,316;23:111, 115,131;25:450 Lenzites betulina 29:266;291 Leocarpus fragilis 21:414 Leontice leontopetalum 9:153 Leontodon hispidus 29:90 Leonurus cardiaca L. 22:525;30:273 for epilepsy 22:525 isoquercitrin from 30:273 Leonurus hereteropyllus 25:272 Lepidine 3:396 Lepidium sativum 21:98,109;25:781; 27:217;28:400 in tick toxicity 28:400 Lepidoglyphus 28:432 Lepidoptera 9:322,772;22:371 ;22:376, 381 Leprae 26:1155 c~,13-Leprosols 9:322,338,345 Leptine I 7:18;21:84 Leptinidine (23 [3-hydroxysolanidine) 7:18,22 Leptinotarsa decemlineata 26:850,854, 855,869-872,874,876 Leptochilus acolhuus 5:223,224,253 Leptoclinides dubius 25:719 Leptocoris trivittatus 22:386 Leptodactylin 15:328 Leptodontium elatius 21:193;22:253; 23:344 Leptogenys diminuta 11:415 (3R,4S)-4-methyl-3-heptanol from 11:415 Leptogorgia virgulata 17:99 Leptomonas collosoma 2:301 Leptomonas samueli 2:298 polysaccharides of 2:301 Leptophyllin-A 20:486,487 Leptophyllin-B 20:486,487 Leptosin B 25:839 Leptosin C 25:839,840 Leptosin D 25:839 Leptosin E 25:839 Leptosin F 25:839
471
Leptosin G 25:839 Leptosin G~ 25:839 Leptosin G2 25:839 Leptosin H 25:839 Leptosin I 25:839 Leptosin J 25:839 Leptosin K 25:839,840 Leptosin K2 25:839 Leptosin KI 25:839 Leptosins 25:838,839 Leptosm A 25:839,840 Leptosphaeria oraemasis 22:72 Leptosphaeria sp. 25:839,901 Lepto~phaerisa oraemaris 23:344 LeSBTI 25:392 Lesion 22:441 Lespedeza capitata 29:580 Lespedeza sericea 22:95 Lesquerella sp. 13:310 Lethality bioassay 9:385,387,388, of brine shrimp 9:385,387,388, 399,400 Lethaloxin 26:451 Letharia vulpina 5:310,311,313 Lethasterias nanimensis chelifera 15:59 Leucadendron 4:712 Leucaena leucocephala 26:1142,1148 galactomannans from 26:1148 Leucaena spp. 26:1139 Leucas lavandulifolia 22:525 for convulsion, epileptic seizures and coughing spasms 22:525 Leucas zeylanica R. Br. 22:525 Leucetta chagosensis 17:17 Leucetta microraphis 25:705 Leucettamine A 25:705 tert-Leucine 21:297 Leucine 21:738;23:97;25:331 Leucine aminopeptidase 12:434;25:375 Leucine aminopeptidase A 12:434 Leucine rich repeat (LRR.) domain 25:398,402 Leucine-enkephalin (L-ENK) 27:798 Leucocyclusformosus 10:151 ;21:378 Leucodopachrome 16:614 Leucodrin 4:712 Leucogyrophana 29:271 Leucojum aestivum 20:359 Leucojum vernum 20:359
Leucomelone 29:299 synthesis of 29:299 Leucomitomycin C 13:436 Leucomycin A3 5:611,612 Leucomycins 11:164 Leuconitis eugenifolia A. 29:362 Leuconolide A~ 11:163,170 Leuconolide A3 11:163,170 Leuconolides 11:160,163-172 stereoselective synthesis of 11:163-172 Leuconostoc measenteroides 2:350,314, 325;7:69 Leuconotis 29:363 Leucopaxillus albissimus 26:493 Leucopaxilus cerealis var. piceina 21:190 Leucophaea maderae 9:488,489 Leucoquinazirine 4:351 Leucosceptoside 27:837 Leucotriene B4 10:168 synthesis of 10:168 (+)-Leucoxylonine 16:505 Leudrin 4:712 Leu-enkephalin 27:802,803 Leukamenin E 15:175 from Rabdosia umbrosa var. latifolia 15:175 Leukemia 1:275 P-388Leukemia 24:190 Leukemia cells 23:74,186 cytotoxic activity against 23:78, 172,177,180,186,234,649,679, 797,800 ofherbimycin A 23:72,74,90 Leukemia HL-60 cells 21:636 Leukemia P-388 19:558;25:760 Leukocyte activity 26:510 Leukocyte degranulation 30:70 inhibitory action on 30:70 Leukocytes 22:112,437;30:59,60,64,66, 67,70 effect of carp oil on 30:66 effect of oleic acid on 30:65 effect of triterpenoid fraction on 30:60 in LLC-bearing mice 30:59,64 inhibitory action on 30:70 Leukocytopenia 26:243
472 Leukoencephalmalacia 9:215 Leukopenia 5:135;25:431 Leukotriene B4 25:275,617,815,939; 30:70 qinhibitory action on 30:70 Leukotriene B4 production 25:615 Leukotriene B3 10:159,12:399 synthesis of 10:159,12:399 Leukotriene B4 receptor 25:705 Leukotriene biosynthesis 30:225 inhibition of 30:225 Leukotrienes 1:528;5:513,9:368,559, 560;17:642;22:126,434,437;25:274, 275,939-940;30:192,225 and macrophages 30:192 as pain mediator 30:192 biosynthesis of 9:562,576 from arachadonic acid 30:225 LTC4 type of 30:225 LTD4 type of 30:225 LTE4 type of 30:225 peptidoleukotrienes type of 30:225 role in allergy processes 30:225 role in inflammation 30:225 semi-synthesis of 17:642 Leuocylus formosus 24:686,689 Leurocristine 13:655 from Catharanthus roseus 13:655 Leurosidine 14:813,840-846 enantioseletive synthesis of 14:840-846 from anhydrovinblastine 14:871 oxidation of 14:813 3'-oxoleurosidine from 14:813 Leurosine 14:820,821 biosynthesis of 14:820,821 cleavamine from 14:862,863 conversion to anhydrovinblastine 5:186,189 deacetylvindoline from 14:862, 863 20'-deoxyvinblastine from 14:863,864 Na-demethyl-Na-formylleurosine from 14:818,819 from anhydrovinblastine 14:820, 821,871,872
from Catharanthus roseus 14:859 from 15[3,20[3-epoxydihydrocatharanthine 14:871,872 from leurosine N-oxide 14:864 (15'R)- 15'-hydroxycatharinine 14:813,814 oxidation of 14:813,814 3'-oxoleurosine from 14:813,814 21'-oxoleurosine from 14:813, 814 synthesis of 14:811 vinblastine from 14:860 Leurosine N-oxide 14:864 leurosine from 14:864 Leurosinone 5:144-146 Leuteoline 22:423 Leutiginoside alkaloid 27:251 structure of 27:251 Levamisole 26:440,454,485 Levansucrase 8:353 from Bacillus subtilis 8:353 Levisticum 29:581,582 Levoglucosan 12:44,45 c~-methyl aldehyde from 12:45 Levoglucosenone 14:267,276,277 (-)-allo-yohimbane from 14;267, 276,277 (-)-eldar ~ide from 14:272,273 (-)-trans-cognac lactone from 14:272,273 (-)-trans-whisky lactone from 14:272,273 (-)-6-multistriatin from 14:273, 274 (+)-multistriatin from 14:267 (S)- 5-hydroxy- 2-penten-4-o lide from 14:273,274 cycloaddition of 14:270,271 from D-galactose 14:267 Michael addition reaction of 14:271,272 oligomerization of 14:271,272, 274 Prelog-Djerassi lactonic acid from 14:267 preparation of 14:268 purpurosamine C from 14:268
473 reaction of carbonyl group 14:268,269 reaction of double bond 14:269, 270 reserpine from 14:267 serricornin from 14:267,275 synthesis of 14:267,268 tetrodotoxin from 14:267,276, 277 Lbvy and co-workers 29:373,401 rhazinilam synthesis by 29:373, 401 Lew and Kim 29:488 thiocarbapyranoses synthesis by 29:488 Lewis acid catalysis 11:446-451 Lewis lung carcinoma 19:609;30:59 in vitro 30:59 Lexitropsins 5:567,578 Ley synthesis 12:22-24 ofavermectin Bla 12:22-24 Ley's procedure 6:13 in (+)-polygodial synthesis 6:13 Leyssera guaphaloides 25:250 LIA-0788 21:414 Liangshanin A 15:114 n3C-NMR of 15:128 from Rabdosia liangshanica 15:172 ~H-NMR of 15:121 Liangshanin B 15:114 Liangshanin C 15:114 Liangshanin D 15:115 from Rabdosia liangshanica 15:172 nH-NMR of 15:122 Liangshanin E 15:115 n3C-NMR of 15:129 from Rabdosia liangshanica 15:172 IH-NMR of 15:122 Liangshanin F 15:116 t3C-NMR of 15:129 from Rabdosia liangshanica 15:172 ~H-NMR of 15:123 Liangshanin G 15:114 X3C-NMR of 15:128 from Rabdosia liangshanica
15:172 IH-NMR of 15:121 Liatris cylindracea 24:103 Liatris platylepis 24:103 Libinia emarginata 1:704 juvenile hormone from 1:704 Libium maximowiczii 25:788 Libocedrus bidwilli 26:231 Licania apetala vat. apetala 28:41,58 Licania carii 28:38,40-42,60 betulinic acid from 28:42 2ot-hydroxyursolic acid from 28:42 maslinic acid from 28:42 myricetin 3'-methyl-3-Orutinoside from 28:42 myricetin 3-O-(2"-O-fS-Dxylop yrano syl )-cx-L-rha mn opyranoside from 28:42 myricetin 3-O-rutinoside from 28:42 myricetin 3-O-f3-Dgalactopyranoside from 28:42 myricetin 3-O-~-Dglucopyranoside from 28:42 phytochemical studies of 28:38 quercetin 3-O-(2"-O-~-Dxylopyranosyl)-c~-Lrhamnopyranoside from 28:42 quercetin 3-O-rutinoside from 28:42 quercetin 3-O-~-Dgalactopyranoside from 28:42 quercetin 3-O-~-Dglucopyranoside from 28:42 p-sitosterol 3-O-fS-Dglucupyranoside from 28:42 ursolic acid from 28:42 Licania densiflora 28:38,49 3',4'-dimethylmyricetin-3-O-[3D-glucopyranoside from 28:49 myricetin 3 ',5'-dimethylether-3O-cx-L-rhamnoside from 28:49 myricetin 3 ',5'-dimethylether-3O-[3-D-glucopyranoside from 28:49 myricetin 3'-methylether-3-O-13D-galactopyranoside from
474 28:49 myricetin 3-O-( 2"-O-ct-Lrhamnopyranosyl)-ec-Lrhamnopyranoside from 28:49 myricetin 4'-methylether-3-O-etL-rhamnopyranoside from 28:49 naringenin 8-hydroxy-4'-methyl ether from 28:49 phytochemical studies of 28:38 Licania genus 28:35,65 biological studies on 28:35 Licania heteromorpha 28:65 Licania heteromorpha var. heteromorpha 28:38,40,53, 62 alphitolic acid from 28:53 betulinic acid from 28:53 myricetin 3,4'-di-O-ct-Lrhamnopyranoside from 28:53 myricetin 3-O-ct-Lrhamnopyranoside from 28:53 myricetin 3-O-~-Dgalactopyranoside from 28:53 myricetin 4'-methylether-3-O-ctL-rhamnopyranoside from 28:53 myricetin 4'-methylether-3-O-[3D-galactopyranoside from 28:53 myricetin 4'-methylether-3-O-13D-glucopyranoside from 28:53 myricetin 7-methylether 3,4'-diO-c~-L-rhamnopyranoside from 28:53 3 f3-O-cis-p-coumaro yl alphitolic acid from 28:53 3 ~-O-cis-p-coumaro yl maslinic acid from 28:53 3 ~-O-cis-p- coumaroyl-2 c~hydroxy-urs- 12-en-28-oic acid from 28:53 3 ~-O-trans-p-coumaro yl alphitolic acid from 28:53 3 ~-O-trans-p-coumaro yl maslinic acid from 28:53 3 f3-O-trans-p- coumaro yl-2 ahydroxy-urs- 12-en-28-oic acid
from 28:53 phytochemical studies of 28:38 Licania heteromorpha var. heteromorpha 28:62 anti-microbial activity of 28:62 Licania intrapetiolaris 28:38 cucurbitacin B from 28:59 intrapetacin A from 28:59 intrapetacin B from 28:59 phytochemical studies of 28:38 Licania licaniaeflora 28:38,40,56,63 anti-oxidant activity of 28:63 arjunic acid 28-D-D-glucosyl ester from 28:57 betulinic acid from 28:57 maslinic acid from 28:57 olean- 12-ene-2c~,3[3-diol from 28:57 oleanolic acid 3-O-~-Larabinopyranoside from 28:57 oleanolic acid from 28:57 pomolic acid from 28:57 phytochemical studies on 28:38 tormentic acid 28-[3-D-glucosyl ester from 28:57 ursolic acid from 28:57 Licania michauxii 28:65 Licania pittieri 28:38,42,60 catechin from 28:42 epicatechin from 28:42 phytochemical studies of 28:38 quercetin from 28:42 quercetin 3-O-ct-Larabinopyranoside from 28:42 quercetin 3-O-c~-Lrhanmopyranoside from 28:42 quercetin 3-O-fS-Dgalactopyranoside from 28:42 quercetin 3-O-[5-Dglucopyranoside from 28:42 ursolic acid from 28:42 Licania pyrifolia 28:38,40,42 ct-amyrin from 28:42 betulin from 28:42 betulinic acid from 28:44 2,3-dihydroxylup- 12-en-28-oic acid 3-(3 ',4'-dihydroxy-benzoyl ester) from 28:44,45
475
2a,3 c~-dihydroxyurs- 12-ene-28oic acid from 28:45 euscaphic acid 28-[3-Dglucopyranosyl ester from 28:45 euscaphic acid from 28:45 11c~-hydroxybetulinic acid from 28:44 613-hydroxybetulinic acid from 28:44 2c~-hydroxyursolic acid from 28:45 lupeol from 28:42 maslinic acid from 28:45 oleanolic acid from 28:44 phytochemical studies of 28:38 13-sitosterol 3-O-[3-Dglucopyranoside from 28:45 [3-sitosterol from 28:42 tormentic acid 28-[3-Dglucopyranosyl ester from 28:45 tormentic acid from 28:45 2,3,27-trihydroxylup- 12-en-28oic acid 3-(3 '-4'-dihydroxybenzoyl ester) from 28:45 ursolic acid 3-O-a-Larabinopyranoside from 28:45 ursolic acid from 28:44 uvaol from 28:44 Licaria puchury 22:525 Licarin A 26:247 Licarin B 26:858 Licarin C 26:202 Licarin D 26:247 Lichenan 5:309-311,322 Lichenan polysaccharide (PS) 30:412 from moss 30:412 Lichens 9:317,328 LiC104 8:166,167 as supporting electrolyte 8:166, 167 Licochalcone 21:740-744 bioactivity of 21:744 synthesis of 21:741-743 Licochalcone A 26:800,801 ;28:224 anti-Helicobacter pylori activity of 28:241
anti-microbial activity of 28:224 biological activity of 28:229 Licochalcone B 28:226 anti-human immunodeficiency virus (HIV) activity of 28:226 anti-Helicobacter pylori activity of 28:241 anti-microbial activity of 28:224 biological activity of 28:229 Licochalcones A and B 27:425 structure of 27:427,428 Licoflavonol 28:229 biological activity of 28:229 Licohalcone A 21:742,743,744 Licoisoflavanone 28:229 biological activity of 28:229 Licoisoflavone 4:378,383 synthesis of 4:378,383 Licoisoflavone A 28:229 biological activity of 28:229 Licoisoflavone B 28:224 anti-Helicobacter pylori activity of 28:241 anti-microbial activity of 28:224 biological activity of 28:229 ~,-Licorane 3:431 synthesis of 3:431 Licorice 21:740;26:745;28:204,205 anti-hepatitic principles from 28:205 antitussives from 28:205 anti-ulcer compounds from 28:205 dihydrophenanthrene from 28:205 dihydrostilbenes from 28:205 flavor from 28:205 isoliquiritigenin from 28:205 isoliquiritin from 28:205 liquiritigenin glycosides from 28:205 liquiritin apioside from 28:205 liquiritin from 28:205 sweetening agents from 28:205 Licorice flavonoids 28:224 anti-Helicobacter pylori activity of 28:234 anti-microbial activity of 28:62, 224,257,293
476 Licorice root 22:422 Licorice-saponin 28:241 anti-Helicobacter pylori activity of 28:241 Licoricidin 28:241 anti-Helicobacter pylori activity of 28:241 anti-microbial activity of 28:62,224,257,293 biological activity of 28:229 Licoricone 4:378,383;28:224 anti-Helicobacter pylori activity of 28:243 anti-microbial activity of 28:224 biological activity of 28:229 synthesis of 4:378,383 Licorisoflavan A 28:229 biological activity of 28:229 Lienomycin 6:261 relative configuration of 6:251 Liensinine 21:79 Ligand 30:799,808 opioid receptivity of 30:808 Ligand-gated channel 21:11,14,20 Ligand-gated ion channel 25:527 neurotransmitter receptor 25:527 Ligand-receptor interactions 19:240 Ligase 17:480 Light 2:155,156 circularly polarized 2:154 interactions with molecules 2:155,156 linearly polarized 2:153 Light scanning detection (LSD) 18:195 Liginine 25:126 Ligistrum 26:327 Lignan constituents 30:588 against cancer cell lines 30:588 Lignan podophyllotoxin 13:654 Lignans 5:9,459,503,753,754,311; 17:313,441 ;20:108-113,273,613; 24:215,228-232,503-509,739-798; 26:229,790,813,887 ;30:560,562,567, 570,590,594 ;24:215,228-232,739798;26:206,207 antileishmanial activity of 26:229,790,813,887 antiperoxidative effects of 26:249-255
antiplatelet aggregation due to 30:560 as antiviral compound 24:503-509 as phytoestrogens 26:206,207 biological activity of 5:505,544, 545;24:739 cytotoxicity due to 30:560 Epstein-Barr virus inhibition due to 30:560 from Abies sachalinesis 20:613-620 from Hernandia ovigera 18:551 from Salix sachalinensis 20:627 parasiticidal activity of 26:229 synthesis of 18:551;24:739 transformations of 24:739 turbidimetry assay 30:594 Lignarenones A,B 10:152,167,171 synthesis of 10:167,171 Lignicolous fungi 22:69,74,72 Lignin 5:309-311,322,461-463,467, 472;26:1262 Lignin polymer 27:760 Lignincola laenis 25:899 Lignothioglycolic acid 25:668 Ligstroside 26:318,333,334,343 Ligularia fischeri 29:87 Ligularone 4:615 synthesis of 4:615 Liliaceae 6:487;7:427;17:130;21:129, 644,668,673,674 saponin from 21:643 Lilium candidum 21:128 lilaline from 21:128 Lilium longifolium 18:507;21:643; 25:391 teasterone myristate from 18:507 teasterone 3-myristate from 18:495,522 Lilium nobilissimum 21:643 Lilium speciosum 21:643 Lillium candidum 21:128 Lillium maximowezii 23:341 Limatine 1:40 Limatinine 1:40 Limatulone 17:26,27
477
Limbic brain regions 30:383 serotonin (5-HT) receptors in 30:383 Limbinol 20:683 from Salvia limbata 20:683 Li-methylsulfynil carbanion 27:512 Limettin 23:352 Limnocorrals 26:381 Limnophila chinensis 22:525 as antispasmodic 22:525 Limocin A 9:300,302,303 Limocin B 9:300,302,303 Limocinin 9:300,304,305 Limocinol (tirucalla-7,24-dien 1613-ol) 9:300,301 Limocinone 9:300-303 Limocitrin rhamnoside 25:594 Limocrocine 21:374,405,407 Limonen 20:6,13,16 Limonen- 1,2-oxide 29:83 activity in lung-1, RAS bioassay system 29:83 (+)-Limonene 5:702;10:412;15:257; 21:585;27:372 Nazarov cyclization of 10:412 (-)-Limonene 16:211,216;21:585 Limonene 16:211,221,260;20:6,13,16; 21:574,599,600,607,614 ;25:44,125, 133,140,145-147,149,150,15130:723 structure of 30:723 (d)-Limonene 21:585,618,621 8-Limonene 23:818 d-Limonene 27:386;29:83 activity in AM assay system 29:83 activity in GPx assay system 29:83 activity in GST assay system 29:83 activity in NFkB assay system 29:83 activity in RAS assay system 29:83 activity in mam-1 assay system 29:83 activity in mam-2 assay system 29:83 activity in stoma assay system 29:83
activity in AM assay system 29:83 activity in TPA assay system 29:83 activity in liver-1 assay system 29:83 activity in lung-1 assay system 29:83 activity in AM assay system 29:83 R-(+)-Limonene 5:732,733;8:48;16:208 S-(-)-Limonene 6:74,75;16:208,225 (-)-pseudopterosin A from 6:74, 75 (+)-Limonene oxide 19:205 Limonene- 1,2-diol 29:83 activity in RAS assay system 29:83 Limonene- 1,2-epoxide 25:150 Limonene- 1,2-epoxide hydrolase 25:150 Limonene- 1,2-oxide 16:208,217 (+)-Limonene-l,2-(-)trans-diol 25:147, 150 Limonia acidissima L. 20:497;22:525 for epilepsy 22:525 Limonia crenulata 22:525 for epilepsy 22:525 Limonin 9:307 D-seco-Limonoids 26:815 Limonoids 9:307,20:492;22:146 from Trichilia emetica 20:492 Linalool 13:332;20:587;21:589,600, 602,607,612,615;22:509,511,537; 25:125,136,140,142,162;26:396,397; 28:406,413;29:83 acaricidal activity of 28:412 acaricidal properties of 28:406 activity in RAS assay system 29:83 activity in TPA assay system 29:83 analysis of 28:413 epoxide of 26:397 O-Linalool 25:141,147 (R)-(-)-Linalool 25:143 (+)-Linalool 27:384 Linalool enantiomers 27:379 Linalool epoxide 25:143
478 Linalool-8-carboxylic acid 25:141 Linalyl acetate 17:604;25:136,140,141; 27:374 structure of 27:374 (-)-(3R)-Linalyl diphosphate 11:220 Linaria saxatilis var.glutinosa 29:689 Linarioside 7:440 Linckia guildingi 7:298 Linckia laevigata 7:290,295,46,61 laevigatoside from 7:290 maculatoside from 7:290 marthasteroside A1 from 7:290 ophidianoside F from 7:290 thornasteroside A from 7:290 Lincomycin 1:429 Lincosamine 11:429 and galacto configuration 4:147, 148 by [4+2] cycloaddition 4:145 from D-threonine 4:140-143, 145,147,148,: 140,141 synthesis of 4:140-143,145,147, 148 Lincosamine derivative 4:145 by cis-hydroxylation 4:145 Lindbladia tubulina 29:254 Lindelofine 1:267 synthesis of 1:267 Lindera umbellata 28:419 Linderazulene 5:368,369;14:315 Lindlar catalyst 6:79,157,559;19:42,594 triple bond reduction 4:532 Linear conformation 11:115 of polyketide 11:115 Linear diterpene 24:282 Linear triquinane 13:34-46 synthesis of 3:14 Linearly polarized light 2:154 Linearol 29:100 activity in NFkB bioassay system 29:100 Lineus fuscoviridis 18:725 Lingbya majuscula 25:876,902 a-Linked 3'-deoxycyclitol 14:147 synthesis of 14:147 13-(1~ 1)-Linked 4,4'-dithiotrisaccharides 8:344-346 synthesis of 8:344-346
[3 (1-~6)-Linked 6-thiodissacharides 8:339 synthesis of 8:339 [3-(1-6)-Linked disaccharides 6:395, 396,403 fl, l-Linked galactose 25:295,316 c~-D-Linked glucans 5:288 Linked scan mass spectra 2:43 1-~2-Linked thiodisaccharides 8:327, 328 synthesis of 8:327,328 1-+3-Linked thiodisaccharides 8:329 synthesis of 8:329 1--~4-Linked thiodisaccharides 8:329-337 1--~6-Linked thiodisaccharides 8:340 1--~6-Linked thiosaccharides 8:338-340 S-Linked thiotrisaccharides 8:340 Linkiol 5:725,727 Linkitriol 5:725,727 p-methoxybenzoate of 5:725,727 Linoleic acid 13:304,305,311,313,659; 21:187,189;22:317;26:361,433,434, 461;27:68;30:65 from carp oil 30:65 lipid peroxidation of 27:59,68, 85,504,505 Linoleic acid (9,12Z)-octadecadienoic acid 9:560-563,565-567,573-575, 581 8-Linolenic acid 26:361 Linolenic acid 23:342;27:70 generation of 16S-hydroperoxy9Z, 12Z, 14E-octa-decatrienoic acid (16S-HPOTE) from 27:70 generation of 9S-hydroperoxy10E, 12Z, 16Z-octadecatrienoic acid from 27:70,71 Linolenic methyl ester 2:11 Linone-l,2-diol 25:146 Linonene epoxide 25:146,147 Lintenolide F & G 25:700 Linum 26:172,173 Linum album 26:173 Linum flavum 26:173,212 5-methoxypodophyllotoxin from 26:212
479 Linum usitatissimum L. 22:525;26:206;
29:608 for hysteria 22:525 Lipase P 1:687,19:153 Lipase PS 16:703 Lipases 13:9,14;24:1005;27:66 enzymatic activity 24:1005 Lipasic enzymatic activity 24:999-1001 Lipid A 28:518,519,523,525,526, 529,534,537,538 acute effects of 28:523 antitumor activities of 28:518 association with immunomodulators 28:534 biological properties of 28:519 effect on acquired immunity 28:529 effect on cytokine production 28:526 effect on innate immunity 28:525 in cancer vaccination 28:537 to treat tumor-bearing animals 28:538 treatment with 28:534 Lipid A DT 5461 28:534 for C38 colon carcinoma 28:535 for Lewis lung carcinoma 28:535 for MH134 hepatoma 28:535 for MM46 mammary carcinoma 28:535 for murine Meth A fibrosarcoma 28:535 treatment with 28:534 Lipid A OM-174 28:536 antitumor activity of 28:536 treatment with 28:536 Lipid A ONO-4007 28:535 treatment with 28:535 Lipid A tolerance 28:521 by anti-LPS antibodies 28:522 Lipid disorders 5:695 Lipid hydroperoxides (LOOHs) 27:59, 67,68, 73,78 degradation products of 27:68 Lipid oxidation 23:767 measurment of 23:768 Lipid oxidation system 23:773
Lipid peroxidation 4:495;27:59,68,85, 504,505 inhibitor of 4:495 oflinoleic acid 27:68 relation with apoptosis 27:86-88 Lipid peroxidation activity 26:253 Lipid peroxidation products 27:84-86 in biological materials 27:84-86 relation with cell death 27:86-88 Lipid storage disease (phytoesterolemia) 9:478 Lipid-diphosphooligo-saccharide 26:1131 Lipid-linked high-mannose oligosaccharide (IV) 10:499 Lipids 24:1009-1015,1050;28:517; 29:233 anti-rumor activity of 28:517 absolute structures of 29:233 lycogarides as 29:233 total fatty acids of 24:1009-1015 triglyceride of 24:1009-1015; 29:233 Lipid-soluble antioxidant 30:322 uniquinone as 30:322 Lipitor atorvastatin 22:252 Lipo-CCK 18:844-848 biological properties of 18:857-863 physical properties of 18:844-848 biological properties of 18:857-863 Lipo-gastrin 18:844-848 biological properties of 18:844848 physical properties of 18:844848 Lipogenesis 27:393 biological activity of 27:393 insulin-induced 27:397 Lipohilicity 15:355 R(+)-ot-Lipoic acid 1:536-538 synthesis of 1:536-538 Lipoic acid 1:600,602 synthesis of 1:600,602 Lipolysis 27:393 biological activity of 27:393
480 Lipolytic action 27:394 activity of 27:394 Lipolytic activity 23:364 of coumarin 23:335,356,357, 353,3 68,376,393,550,553 Lipomannan 26:1155 [3-Lipomycin 28:135 as antibacterial agent 28:135 c~-Lipomycin 28:135 as antibacterial agent 28:135 Lipooxygenase pathway 25:263 Lipooxygenases 25:597,939,940 Lipopeptidophosphoglycan (LPPG) 2:302-309 Lipoperoxidation assay 25:940 Lipoperoxidation process 25:614 Lipophilic antioxidant 30:224 design of 30:224 Lipophilic derivatives 18:840-851 Lipophilicity 4:369 Lipophosphoglycan (LPG) 2:312 from Leishmania donovani 2:312 Lipopolysaccharides (LPS) 25:477,460; 26:597,951,1152;27:856;28:518,520, 521,523,528,533,539;30:420 acute effects of 28:523 antigenic properties of 28:518 biological properties of 28:518 by PROb colon cancer cells 28:533 components of 30:420 effects on angiogenesis 28:528 effects on blood flow 28:528 in human macrophages 28:521 in peritoneal carcinomatosis 28:533 of gram-negative bacteria 30:420 phase I trials with 28:539 receptor for 28:520 role in immunospecificity 30:420 Lipoxins 9:559 biosynthesis of 9:561,575-578 Lipoxygenase 5:521,559-589;13:303, 305,311;21:134 12-Lipoxygenase 25:47 inhibition of 25:47
15-Lipoxygenase 25:47 inhibition of 25:47 5-Lipoxygenase 5:513,514,820;25:47; 30:225 inhibition of 25:47 redox inhibitors of 30:225 Lipoxygenase catalysis 9:559-589 products of 9:559-589 substrate of 9:559-589 5-Lipoxygenase inhibition 30:225 effect of polyhydroxylated 2phenylnaphthalenes 30:225 effect of tetrahydroxypavinan 30:225 5-Lipoxygenase inhibitor 28:215; 30:226 artonin E as 28:201,215 IC50 values of 30:226 5-Lipoxygenase inhibitory activity 2:282,284,335;24:855 of Magnolia liliflora 24:855 Lipoxygenases 27:59,67-69,88 from soybean 27:69,70 of tomatoes 27:70 Lipoxygenation 9:573 oflinoleic acid 13:311 R-Lipoxygenation 9:574,575 Lipozyme activity 20:845 Lippa dulcis Trev. 24:799;27:13,21 (+)-hernandulcin from 27:13,21 4[3-hydroxyheman dulcin from 27:13,21 Lippia alba 21:617 Lippia dauensis 21:595 Lippia grandifolia 21:595 Lippia javanica 21:595 Lippia multiflora 21:613 Lippia nodiflora 5:647,648,655 Lippia somalensis 21:595 Lippia sp. 7:427 Lippia ukambensis 21:595 Lippia wilmsii 21:595 Lipria dulcis 15:14 Liquid chromatography 21:579 Liquid chromatography-mass spectrometry 21:555 Liquid secondary ion mass spectrometry (LIMS) 2:20
481
dispersing matrices 2:20 effect of salts 2:24 of bovine insulin 2:23-25 of methionyl-enkephalin 2:21-23 of peptides 2:20-30 spectrometry (LIMS) 2:20-41 Liquid secondary ionization LSI MS 9:487 Liquid sodium amalgam 11:371 Liquid sodium-potassium alloy 11:371 Liquidamber formosana 23:405 Liquid-Liquid extraction 21:526,527 Liquiritigenin 26:745;28:241 anti-Helicobacter pylori activity of 28:241 anti-microbial activity of 28:224 Liquiritin 28:241 anti-Helicobacter pylori activity of 28:241 anti-microbial activity of 28:224 Liquiritoside 22:423 Lirinidine 21:68,73;22:22 Liriodendrin 26:233 Liriodendron tulipifera 5:476 Liriodenine 2:435-439;9:396,398, 20:483 activity in 2:435,437,439 Lirioresinolglycoside 26:268 13-dimethyl ether of 26:233,268 (-)-Liriorinol B 26:229 Lirodendrin 5:475,476 Lisianthoside 7:443 Lissochinotoxin A 23:236 Lissoclin C 23:263 Lissoclin disulfoxide 25:834,863 Lissoclinamide 1 25:880 Lissoclinamide 2 25:880 Lissoclinamide 3 25:880 Lissoclinamide 4 25:880 Lissoclinamide 5 25:880 Lissoclinamide 6 25:880 Lissoclinamide 7 25:880 Lissoclinamides (1-5) 10:242,243 Lissoclinium patella 25:879,880 Lissoclinotoxins 23:236 Lissoclinotoxin A 10:244;25:834 Lissoclinotoxin B 25:835
Lissoclinotoxin C 23:237;25:835 tris(methylthio) derivatives 25:835 Lissoclinotoxin D 23:237;25:833,835 Lissoclins 25:821 Lissoclinum 25:707,821,833,834,862, 878 Lissoclinum bistratum 10:243;25:881, 882;28:628 bistratamide A from 28:628 bistratamide B from 28:628 bistratamide C from 28:628 bistratamide D from 28:628 Lissoclinum fragile 23:262;25:782 Lissoclinum genus 25:833 Lissoclinumjaponicum 25:833;28:637 dimethyl-5-(methylthio) varaein from 28:637 Lissoclinum lisschlinotoxin A 25:833 Lissoclinum patella 4:89,93,99;5:419, 420;10:242,243 ;25:878,891; 28:622-629 ascidiacyclamide from 28:622 heptapeptide ulicyclamide from 28:622 patellamide A from 28:623 patellamide B from 28:623 patellamide C from 28:623 patellamide E from 28:627 patellamide F from 28:627 patellamide G from 28:627 patellazole A from 28:625 patellazole B from 28:625 patellazole C from 28:625 patellins 1-6 from 28:629 prepatellamide A from 28:626 tawicyclamide A from 28:629 tawicyclamide B from 28:629 trunkamide A from 28:629 ulithiacyclamide from 28:622 ulithiacyclamide B from 28:623 Lissoclinum perforatum 10:244;23:236; 25:833;28:636 1,2,3-trithiane derivative from 28:636 Lissoclinum sp. 28:636 lissoclinotoxin A from 28:636 lissoclinotoxin C from 28:636
482
lissoclinotoxin D from 28:636 trithiane from 28:637 Lissoclinum tunicate 28:715 Lissoclinum vareau 10:243;23:236; 25:871,833 varacin from 28:637 varamine A from 28:638 Lissoclinum voeltakowi Michaelson 25:269 Lissodendoryx isodactyalis 5:395, 13:168;18:715,716 Lissodinum 25:833,834 (-)-Listenolide C~ and C2 16:698-699 Listera ovata 26:1135 Listeria infection 25:431 ;30:766,768 host defense against 30:766 late phase of 30:769 protective mechanism against 30:766 stage of 30:768 with LP-BM5 MuLV 30:766 with murine leukemia viruses 30:766 Listeria monocytogenes 21:618;27:381; 30:766,767,773 host defense against 30:766 in immune response 30:773 Listeria-specific antigens 30:770 Listeria-specific cell-mediated immunity 25:431;30:768 development of 30:768 Litalin flavonoids 26:744 Lithiated 2-acetylthiazole 30:437 Lithiated trimethylsilylacetonitrile 1:311,312 Lithiation 5:827 of 2-methoxy-N, N-diethylbenzamide 5:827 of 3-methoxy-N, N-dimethylbenzylamine 5:828,829 with sec-butyllithium 5:827,828 1-Lithio glycals 10:345 by direct lithiation 10:345 from tributyltin 10:345 2-Lithio-2-phenyl-6-heptene 8:7,8 synthesis of 8:7,8 2-Lithio-3,3-diethoxy- 1-propene 12:36, 40,43
Lithiodianion-imine condensation 4:433,443-448,450,464 2-Lithiofuran 30:469 addition of 30:469 Lithioglycal 10:346 N-Lithioimidazolidines 1:349-351 anionic cycloreversion of 1:349-351 2-azaallyl anions from 1:349-351 Lithistid sponges 26:1175,1176 Lithistida 28:658 Lithium/4,4'-di (tert. butyl) biphenyl (DTBBP) 11:309 Lithium 2-thienylcyanocuprate 21:393 Lithium aluminium hydride 22:288,293 Lithium di (c~-ethoxyvinyl) cuprate addition of 12:25 BF3 OEt2 promoted 12:25 to m 2'3 e n o n e 12:25 (E)-Lithium enolate 30:25,469 oxidation of 30:469 Lithium hexamethydisilazide (LHMDS) 24:9,10 Lithium isopropylcyclohexylamide (LICA) 10:410 Lithium methylcrotyl aluminate 6:298, 299 condensation with 6:298,299 Lithium organocuprates 4:555,556 1,4-addition 4:555,556 Lithium organyls 4:556-558 1,2-addition 4:556-558 Lithium triethyl borohydride 11:423 reduction with 11:83,84 Lithium tri-sec butylborohydride (Lselectride) 11:234 Lithocholic acid 27:858,859 Litholytic properties 26:52,54 of Herniariafontanesii 26:52,54 Lithontriptic 20:79 Lithospermic acid A 30:227 as HIV-1 integrase inhibitors 30:227 structure of 30:227 Lithospermic acid B 30:227 as HIV- 1 integrase inhibitors 30:227 structure of 30:227
483
Lithospermic acids 30:226 effect on HIV-1 infected H9 cells 30:226 Lithospermum 22:76 Lithospermum erythrorhizon 7:88; 30:345 BK-39 callus culture of 30:345 shikonin from 7:88 Lithramine 20:276 L-itronellol 25:125 Litsea cubeha 25:132 Litsea odorifer 24:275 Littorine 17:397;21:56;22:728 Lituaria australasiae 19:596 Lituarines A-C 19:596 Liu-Kulkarni synthesis 6:43,44 Liver 30:64 metastasis in 30:64 Liver cancer 20:528 Liver carcinoma 30:406 Liver disorders 30:637 role of oleanolic acids in 30:637 Liver hepatocytes 30:406 Liver injury 25:461 ;30:637 effect of LPS toxicity on 25:461 effect of TNF-a 25:470 role of oleanolic acids in 30:637 Liver insufficiency 26:1130 as syndrome type-lA 26:1130 Liver intoxication 25:459-462 with D-Gal N/LPS 25:459-461 with D-gal N/TNF-a 25:460,461 Liver metastatic tumor colonies 30:66 effect of oleic acid on 30:65 Liver necrosis 30:406 Liver tumor model (H22) 30:841 effect of Eisenia fetida 30:841 Liver-derived NO 25:471 Liverwort sesquiterpenoids 18:607-646 absolute configuration of 18:607-646 Liverworts 1:719,81,273,277-290 Livestock 30:751 toxic disease 30:751 Lividomycin A 14:186 Lividomycin B 14:145,186 L-Lividosamine 14:144 D-Lividosamine 14:144,186-193 synthesis of 14:186-193
LLC cells 30:65 intrasplenic implantation of 30:65 LLC cells DNA synthesis 30:67,68 effect of oleic acid on 30:67,68 LLC tumor metastasis 30:60 effect of triterpenoid fraction on 30:60 inhibition of 30:60 LLC-bearing mice 30:59,61 leukocytes in 30:59 tumor in 30:61 llludane-dienone 26:716 LL-Z1271a 28:473,495 anti-fungal activity of 28:473 synthesis of 28:495 L-malic acid 30:38,39 (2S,3S)-2-ethyl-3,4-isopropylidene dioxypropan-l-ol from 30:39 role in (-)-pironetin synthesis 30:38 L-norepinephrine 25:530 lnositol-l,3,4,5-tetraphosphate acid 25:516 LO" radicals 27:78,79 generation of 27:78 Lobane diterpenes 21:276 Lobaria retigera 13:22 (-)-retigeranic acid from 13:22 Lobatetraene 21:276 3,4-Lobatin 26:808 Lobatin A&B 26:808,809 Lobatoside B-E 21:634 Lobatosides 15:191 Lobatrienediol 21:276,277 Lobelia inflata L. 22:525;29:583 for epilepsy, hysteria and convulsions 22:525 Lobeline 21:96,97,102,109,108 (-)-Lobeline 22:17 c~-Lobeline 27:283 (7E)-Lobohedleolide 10:13,14 Lobohedleolide 8:15,14,5,13,14 inhibition of hela cells growth 8:16 ofhela cells 8:16 Lobophylum crassum 8:11 isolobophytolide from 8:20
484
Lobophytum pauciflorum 21:276 Lobophytum sp. 21:276 Lochneram 13:387 Lochnericine 2:375 20-epi-Lochneridine 1:32,127 Lochneridine 1:36;5:172 Lochnerine 9:174,386,429 Loco syndrome 7:71 Locois 27:523 Locomotor activity 21:749 Locusta 9:489 Locusta migratoria 22:387,398;24:115, 116;29:6 Locusta migratoria manilensis 18:771 Locusta migratoria migratorides 7:395, 18:771 Lodoperoxidase 25:758 Lofentanil 30:200 as morphine analogue 30:200 Loganiaceae 6:520,530 pyrido [4,3B] carbazole alkaloids in 6:507 (+)-Loganin 16:294 synthesis of 16:294 Loganin 6:503,529;7:440,455,470; 20:47 strychonovoine from 6:524 Loganin aglycone silyl ether 16:293 from Strychons nux vomica 16:293 synthesis of 16:293-294 Loganin derivatives 6:524 Loliolide 29:111 activity in EBV bioassay system 29:111 Lolium multiflorum Lam. 27:217 Lolium perenne L. 26:696;27:217 Lollo rosso 23:759 HPLC chromatogram 23:759 Lombardo methylenation 6:209 Lombardo reagent 11:40,41 methylenation with 11:40,41 Lonchocarpus 26:487 Lonchocarpus capassa 29:598 Lonchocarpus minimiflorus 29:782 Lonchocarpus subglauscescens 29:780 Lonchocarpus urucu 28:435
Lonchura malabarica 5:837 hemoglobin components of 5:837 Lonchura malacca 5:837 hemoglobin components of 5:837 Lonchura punctulata 5:837 hemoglobin components of 5:837 Long range heteronuclear COSY spectrum 2:147-151 isomycorhodin 2:150 Long range 13C-1H-COSY spectrum 2:93,95 of 20 (S)-hydroxydammaran-3one 2:39,94 of dendropanoxide 2:100 of marchantin A trimethyl ether 2:107,112 ofsacculaplagin triacetate 2:87 Long range HETCOR 9:147,151,153 Longamide B 25:777,778 Longamides 25:757 Long-chain sugars 14:179 (+)-Longiborneol 4:675 (+)-Longicamphor 4:675 Longicaudatine 26:1051 Longicaudosides A,B 7:309,94 from Ophiderma longicaudum 7:308 Longifolene 4:675;7:110;16:136,608 to isologifolene 4:639 Longifolin 21:361 Longikaurin A 15:138,145 13C-NMR of 15:155 from Rabdosia longituba 15:173 from Rabdosia ternifolia 15:175 ~H-NMR of 15:156 Longikaurin B 15:139 ~3C-NMR of 15:156 from Rabdosia longituba 15:173 ~H-NMR of 15:147 Longikaurin D 15:175 from Rabdosia trichocarpa 15:175 Longikaurin G 15:139 13C-NMR of 15:156 from Rabdosia longituba 15:172 ~H-NMR of 15:147
485
Longilactone 23:301 Longilobol 7:218 from Artemisia longiloba 7:218 Longipinane derivatives 7:218 cis-Longipinane-2,7-dione 27:587 trans-Longipinane-2,7-dione 27:587 Longipinen 8:33,37 synthesis of 8:33,37 Longipinen-7-ol 9:534 NOED spectra of 9:534 c~-Longipinene 8:33,37 synthesis of 8:33,37 [~-Longipinene 8:33,37 synthesis of 8:33,37 (+)-c~-Longipinene 8:37 synthesis of 8:37 (+)-[3-Longipinene 8:37 synthesis of 8:37 Longirabdosin 15:116,123,135,173 from Rabdosia longituba 15:173 ~H-NMR of 15:123 Longispinogein 22:122 Longitin 30:285 1H-NMR spectral data of 30:285 Long-rang 8C/8H COSYspectrum 2:115, 261,263 Long-range ~3C-~H-shift correlation spectrum 5:507 of acteoside 5:507 Long-range C-H couplings 2:115-135 in aromatic compounds 2:115-135 Lonicera fulvotomentosa 21:656 fulvotomentosides from 21:656 Lonicera nigra 7:427 Lonomycin 19:128 Loperamide 30:200 antidiarrheoal activity of 30:200 Lophanthoidin A 15:167,168-170 13C-NMR of 15:170 from Rabdosia lophanthoides 15:173 tH-NMR of 15:169 Lophanthoidin B 15:168-170 13C-NMR of 15:170 from Rabdosia lophanthoides 15:173 ~H-NMR of 15:169
Lophanthoidin C 15:168 from Rabdosia lophanthoides 15:173 IH-NMR of 15:169 Lophanthoidin D 15:168 from Rabdosia lophanthoides 15:173 tH-NMR of 15:169 Lophanthoidin E 15:168-170 13C-NMR of 15:170 from Rabdosia lophanthoides 15:173 ~H-NMR of 15:169 Lophanthoidin F 15:168-170 13C-NMR of 15:170 from Rabdosia lophanthoides 15:173 ~H-NMR of 15:169 Lopharia papyracea 29:265 Lophozozymus pictor 5:393 Loreainide 30:200 antiarrhythmic activity of 30:200 Loropetalin A 23:407 Loropetalin B 23:405 Loropetalum chinense 23:405 Lossen rearrangement 26:1074 Lotus corriculatus 25:93 Lotus uliginous 19:117 Lovastatin 21:211,212;22:255;23:582 LoVo tumor cell 21:165 Low density lipoprotein 27:846 chemical degradation of 27:846 Lowary and Callam 29:457 carbafuranose synthesis by 29:457 Lowry method 25:435 Low-temperature NMR analysis 27:344 Low-valent titanium 4:521-535 from reductive elimination 4:521-535 Low-valent titanium reagent 11:364 keto aldehydes with 11:364 preparation of 11:364 3 [3-H-Lpecoside 26:97 LPLC 7:407,408,410,415,418 antigenic specificity of 4:195 6-deoxy-D-mannoheptose in 4:195 interleukin I induction by 4:197
486
LPS 25:466 hepatic intoxication with 25:466 LPS hepatotoxicity 25:461,462 LPS induced liver injury 25:475 LPS stimulation 25:475 LPS toxicity 25:461 effects on liver injury 25:461 LPS-beated macrophages 25:473 LPS-elicited hepatocyte apoptosis 25:463 LPS-elicited liver injury 25:463 LPS-induced Ca 2§ elevation 25:475 LPS-induced hepatocyte apoptosis 25:463,471 LPS-induced nitric oxide 25:471 LPS-induced TNFa production 25:470 LPS-related liver injury models 25:463 (+)-lsopiperitenone 25:150 [3-1sopropenyl pimelicacid 25:145 10-1sothiocyanato-5-amorphene-4-ol 25:852 (-)- 13-1sothiocyanatocubebane 25:853 (-)- 10-1sothiocyanatokalihinol C 25:852 (-)-9-1sothiocyanatotrachyopsane 25:853 LSPD experiments 2:111 ofmarchantin A 2:108,112 p-Ltalicum 25:145 LTP-blocking effect 25:966 of ethanol 25:966 L-Tryptophan 25:652 L-Tyrosine 25:652 Luaraceae 21:616 Lucenin 2 7:207 Luche reaction 1:474 Luche reduction 14:126,19:372-373 Luche-type reduction 4:130 with (x,13-unsaturated ketone 4:130 Lucidene 751 Lucidin 26:640,657,661,674,675,670 Lucidin glucoside 26:661 Lucidin primeveroside 26:642,662,676 Lucidin 03-ethylether 26:661,676 Lucidin 03-methylether 26:662,676 Lucosceptoside 25:543 Ludalbin 7:232 Ludongnin 15:112
Ludongnin A 15:112,141 13C-NMR of 15:158 from Rabdosia rubescens 15:174 from Rabdosia rubescens var. lushiensis 15:174 IH-NMR of 15:149 Ludongnin B 15:141 13C-NMR of 15:158 from Rabdosia rubescens 15:174 from Rabdosia rubescens vat. lushiensis 15:174 ~H-NMR of 15:149 Ludovicin A 27:553 Ludovicin A-C 7:232 Ludovicin B 27:553 1-epi-Ludovicin C 27:554 Luffa acutangula 29:615 Luffa cylindrica 21:671 ;22:116,120; 29:575,587,615 Luffariella variabilis 17:10;18:717; 21:252;25:696 Luffariellin A and B 18:717 Luffariellin A-D 17:10 Lugrandoside 26:328 Luidia maculata 7:303-306,15:46 luidiaglycosides A-D from 7:288 maculatoside from 7:289 marthasterosides from 7:289 thomasteroside A from 7:289 Luidiaglycosides A-D 7:288,289,293 from Luidia maculata 7:288 Lukes-Sorm dilactam 6:441,442,444 Lukianols 23:242,245 Lumbricus 30:828 from Lumbricidae family 30:828 Lumbricus bimastus 30:827,828 from Lumbricidae family 30:828 Lumbricus castaneus 30:828 from Lumbricidae family 30:828 Lumbricus rubellus (humus earthworm) 30:826-828,833 assay of 30:833 earthworm fibrinolytic enzymes from 30:826 from Lumbricidae family 30:828 isozymes of 30:826 lyophilized powder of 30:840 Lumbricus terrestris (common earthworm) 30:828
487
from Lumbricidae family 30:828 ~-Lumicolchicine 5:47-49 [3-Lumicolchicine 5:47-49 Luminol-enhanced chemiluminescence 22:346 Lumnitzera sp. 7:176 Lupeol 7:189 Lunacarine 3:385,386 Lunaric acid 2:288,289;22:630,631 Lundt and Horneman 29:456 carbafuranose synthesis by 29:456 Lung tumors 25:46 induced by 4-(methylnitrosamino)-l-(3- pyridyl)- 1butanone (NNK) 25:46 Lungshengrabdosin 15:120 13C-NMR of 15:134 from Rabdosia lungshengensis 15:173 ~H-NMR of 15:127 Lupane 23:692 Lupane triterpenes 22:105,117 Lupane triterpenoids 24:457;25:60,61 FPTase inhibition by 24:457 Lupanes 22:94;25:61 betulin 25:61 (+)-Lupanine 15:520 Lupanine 21:73,91,95,98 (+)-Lupanine N-oxide 15:523 Lupenyl cation 25:176 Lupeol 9:267,20:698;27:478;29:587 effects on CHY 29:587 from Salvia glutinosa 20:707 from Salvia montbretii 20:704 from Salvia pomifera 20:702 Lupeol acetate 25:62 Lupeol palmitate (lupeol hexadecanoic acid ester) 29:587 effects on CHY 29:587 synthesis from lupeol 29:587 Lupeyl acetate 27:590 Lupin alkaloids 15:519-549 epi-Lupinamine 14:739,742 biomimetic synthesis of 14:739, 742 enantioselective synthesis of 14:741,742
Lupinamine 14:739,742 biomimetic synthesis of 14:739, 742 enantioselective synthesis of 14:741,742 Lupine alkaloids 14:731-768;27:258 biological activity of 27:258 structure of 27:258 synthesis of 14:731-768 Lupinine 14:731,732 from dihydropyran 14:737 from piperidine acetic acid 14:738 selectivity of 14:737,738 synthesis of 14:731,737,738 (-)-Lupinine 15:520 (+)-Lupinine 16:462;18:345,356,370 synthesis of 16:462 Lupinoside PA~ 25:95,104,105,118 Lupinoside PA2 25:95 Lupinoside PA3 25:118 Lupinoside PA4 25:95,104,105,118 Lupinoside PA5 25:95 Lupins 21:98 Lupinus albus 26:931 ;27:271,276 Lupinus anagyroides 27:283 Lupinus angustifolius 27:276 Lupinus hartwegii 27:273 Lupinus luteus 15:521 ;27:267;29:587, 782 (-)-( trans-4'-[3-Oglucopyranosyloxy-cinnamoyl) lupinine from 15:521 (-)-(trans-4'-[3-Dglucopyranosyloxy-3 'methoxycinnamoyl) lupinine from 15:521 (- )-( tra ns-4 ' -hydro x y-c inna mo yl ) lupinine from 15:521 (-)-( trans-4 ' -rhamnos ylo x ycinnamoyl) lupinine from 15:521 (-)-(trans-4 '-rhamnos yloxy-3 'methoxy-cinnamoyl) lupinine from 15:521 Lupinus mutabilis 27:278 Lupinus polyphylus 25:94 Lupinus sp. 27:273,268
488
Lupinus termis 15:524,525 (-)-AS-dehydroalbine from 15:524 (-)-ALdehydromultiflorine from 15:525 Lupinus varius 27:273 Lupinyl moiety 27:285 Lupus nephritis 26:269 Lushanrubescensin A 15:120 13C-NMR of 15:134 from Rabdosia rubescens 15:174 from Rabdosia rubescens var. lushiensis 15:174 IH-NMR of 15:127 Lushanrubescensin B 15:120 t3C-NMR of 15:134 from Rabdosia rubescens var. lushiensis 15:174 ~H-NMR of 15:127 Lushanrubescensin C 15:118 13C-NMR of 15:131 from Rabdosia rubescens 15:173 from Rabdosia rubescens var. lushiensis 15:174 ~H-NMR of 15:125 Lushanrubescensin D 15:118 13C-
